P/EPA
United States
Environmental Protection
Agency :
Off ice of
Pesticides and Toxic Substances
Washington, DC 20460
tfA 560/5-83-Oo»
October 1983
Pesticides and Toxic Substances
Chemicals Identified
in Human Breast Milk
A Literature Search
-------
This report is available from the National Technical
Information Service, U.S. Department of Commerce, 5285 Port Royal
Road, Springfield, Virginia 22161.
-------
EPA 560/5-83-009
October 1983
CHEMICALS IDENTIFIED IN HUMAN BREAST MILK,
A LITERATURE SEARCH
Compiled by
M. Virginia Cone, Margaret F. Baldauf,
Dennis M. Opresko and Mary S. Uziel
Chemical Effects Information Center
Information Center Complex/Information Division
Oak Ridge National Laboratory
Oak Ridge, Tennessee 37830
EPA/DOE IAG# DW930139-01-1
Cindy Stroup, EPA Project Officer
Joseph Breen and Janet Remitters, FSB Task Managers
Design and Development Branch
Field Studies Branch
Exposure Evaluation Division
Office of Pesticides and Toxic Substances
401 M Street, S.W.
Washington, D.C. 20460
-------
11
DISCLAIMER
This report was prepared under contract to an agency of the
United States Government. Neither the United States Government
nor any of their employees, contractors, subcontractors, or their
employees, makes any warranty, expressed or implied, nor assumes
any legal liability or responsibility for any third party's use
or the results of such use of any information, apparatus,
product, or process disclosed in th'is report, nor represents that
its use by such third party would not infringe privately-owned
rights.
Publication of the data in this document does not signify
that the contents necessarily reflect the joint or separate views
and policies of each sponsoring agency. Mention of trade names
or commercial products does not constitute endorsement or
recommendation for use.
-------
iii
TABLE OF CONTENTS
Page
INTRODUCTION v
BACKGROUND ON THE COMPREHENSIVE DATA BASE 1
USERS' GUIDE 3
ABBREVIATIONS FOR ANALYTICAL METHODS 5
DATA TABLE 7
REFERENCES FOR DATA TABLE 93
INDICES
CAS PREFERRED NAME INDEX 103
CAS REGISTRY NUNBER 107
CHEMICAL SYNONYM NAME 109
KEYWORD INDEX 122
-------
INTRODUCTION
This computerized literature search for data on chemicals
identified in human breast milk was accomplished for the Office
of Toxic Substances' Exposure Evaluation Division, Environmental
Protection Agency. These data were collected from a
comprehensive human body-burden data base being developed under
the direction of the Environmental Protection Agency and the
National Cancer Institute. The comprehensive data base was
searched for data on chemicals identified in four tissues—the
mammary gland, milk, milk fat and whole milk.
This search is provided to aid in the planning stages of a
National Human Milk Monitoring Study. An objective of this study
will be to obtain national baseline estimates of certain
chemicals in milk.
-------
BACKGROUND ON THE COMPREHENSIVE DATA BASE
A comprehensive human body-burden data base has been
established through the US Environmental Protection Agency/
National Cancer Institute Collaborative Program. The objective
of this effort is to provide a centralized source of information
on chemicals that been identified in human biological media.
Body-burden data are needed by the US government and domestic and
foreign scientists involved in human health research.
Data were obtained primarily from £he open literature
through manual searches (retrospective to 1974) of approximately
85 journals. Data from almost 2400 of the 4400 body-burden
documents collected to date have been entered in the data base as
of October 1982. Over 1000 different chemicals were identified
in human biological media from those sources.
The data base is published annually in tabular format with
indices and chemical listings that allow specific searching. The
file is now available online in the U.S. Department of Energy's
RECON and in Lockheed's DIALOG. The fourth annual report,
October 1982, of "Chemicals Identified in Human Biological Media:
A Data Base" is available.
The comprehensive data was established under aegis of the
Interagency Collaborative Group on Environmental Carcinogensis
(ICGEC), National Cancer Institute. Funding is through the
National Cancer Institute-Environmental Protection Agency
Collaborative Program. The work is being done by the Oak Ridge
National Laboratory's Chemical Effects Information Center,
Information Center Complex, through interagency agreements
involving the National Cancer Institute, the Environmental
Protection Agency, and the Department of Energy. Members of the
ICGEC Task Group on Chemicals in Human Tissues provide support to
the program's activities. Agencies represented by members of the
task group include the Armed Forces Institute of Pathology, the
Center for Disease Control, the Department of Agriculture, the
Department of Energy, the Enviromental Protection Agency, the
Food and Drug Administration, the National Bureau of Standards,
the National Cancer Institute, the National Center for
Toxicological Research, the National Institute for Environmental
Health Sciences, the National Institute for Occupational Safety
and Health, and the National Library of Medicine.
-------
2
To obtain additional information about the comprehensive
data base and copies of the most recent annual report, write to:
Cindy Stroup, Project Officer
Design and Development Branch
Exposure Evaluation Division (TS-798)
Office of Toxic Substances
U.S. Environmental Protection Agency
401 M Street, SW
Washington, DC 20460
Telephone (202) 382-3891
-------
USERS' GUIDE
The emphasis on including recent literature and significant
research documents has resulted in a chronological mix of
articles from 1974 to the present. When body-burden articles are
identified, data are extracted and entered in the data base by
chemical and tissue/body fluid. Each data entry comprises a
single record (or line entry) and is assigned a record number.
If a particular document deals with more than one chemical and/or
tissue, there will be multiple records for that document. For
example, a study of 5 chemicals in each of 3 tissues has 15
different records (or 15 line entries) in the data base with 15
record numbers. Record numbers are assigned consecutively
throughout the entire data base and appear in the upper left
corner of the first column for each record.
The data base is presented in tabular form by chemical,
arranged alphabetically by Chemical Abstracts Service (CAS)
perferred name. The chemical is given along with its CAS
registry number, formula, atomic weight, melting point, boiling
point, and vapor pressure. Tissues are listed alphabetically in
the first column with the record number.
Information in the five columns- EXPOSURE ROUTE, ANALYTICAL
METHOD, NUMBER OF CASES, RANGE, and MEAN- is self-explanatory and
is provided when available in the source document. A list of
abbreviations used for analytical method is provided on page 5.
Exponential values are written as in the following examples:
5 x 10 ~1 is 5 x 10 (E-15). All means are arithmetic unless
designated geometric. When included, standard error is indicated
by S.E. However, values for standard deviations, when given,
have no such designations. When only graphically displayed data
were available, values have been estimated by the extractor and
so indicated in the table under GENERAL INFORMATION.
In the column headed GENERAL INFORMATION, a variety of
information may be included such as that pertinent to the range
and mean as well as experimental design, demography, health
effects, pathology, morphology, toxicity, source, half-life, and
use. Keywords (in uppercase letters) are provided for further
insight into important aspects of the source documents. The use
of a different chemical or tissue as a keyword indicates that
studies in that chemical or tissue were also reporting in the
same document. In general, all supporting information deemed
important for understanding the data presented will appear in
this column.
-------
Review articles are included in the data base; however, no
data have been extracted from such documents since the original
research articles are included. Review articles are designated
in the GENERAL INFORMATION column by the word "Review."
-------
ABBREVIATIONS FOR ANALYTICAL METHODS
AAS Atomic absorption spectrometry
CC Column chromatography
ES Emission spectrometry
GC Gas chromatography
GC-EC Gas chromatography; electron-capture
detection
GC/MS Gas chromatography coupled with mass
spectrometry
HPLC High-pressure liquid chromatography
MS Mass spectrometry
NA Neutron activation
RIA Radioimmunoassay
TLC Thin-layer chromatography
UV Ultraviolet analysis
-------
DATA TABLE
-------
I2S«
11097-69-1
EXACT COHPOSITIOM 0II KM OH V OR OBDETEBBIBED
TISSUE
1
flilk
HPOSDBB BOOT*
..
aBALTTICAL
HBTHOD
CC
GC/HS
BONBEB
OF CASES
a) 6
b) 9
BABGB
a) 0.0 15-0. 03C ppa
b) 0.011-0.032 ppe
BBAB
a) 0.022 ppa
b) 0.018 ppa
GEIEBAl IBFOBKATIOB
a) lev Brunsvick voaen
b) Bova Scotia VOMD
Six lactating aethers learn Ben
Brunsvick and 9 tea* ffova Scotia.
HIM; BBB1ST; CANADA; PESTICIDES;
CBLOBIIMBO HIDPOCABBOBS: CBLOBIIB
OBGABIC COBCOOHOS; BIOACCOHDLATIOI;
LACTATIOIJ POLICBURIBATED BIPBEBTLS;
DDT; DDE
BEFEB8BC5
Husial. C.J.
Hatzinqei. o.
Zitko, T.
Ccockar, J.
197*
Bulletin of
Environmental.
Cootaaination aiid
Toxicology
12(3) : 258-267
Benza&a, cbloco-
108-90-7
C6-H5-C1
C6-H5-C1
HB 112.56, HP -«S C, BP 131.7 C. TP 10 « Bg at 22.2 C
TISSUE
2
Bilk
EIPOSOBB BOOTE
"iMLTTICll
HETBOD
QC/BS
IOBBEB"
OF CaSES
«2
SAUCE
0.1-0.2 ag/al
0.1-0.3 ng/Bl
Traca-0.4 ng/ai
0.1-0.3 nq/al
0.1-10 ng/ai
Tcace-IO ng/al
HBAI
a) 0.12 »oc- 0.1
ng/al
b) 0.16 »or- 0.089
ag/al
c| 0.12 *or- 0. II
ag/al
4) o.16 «or- 0.096
ng/al
a) 1.20 tor- 3.30
ng/al
f) 0.37 »oc- 1.53
ng/al
SE1BBAI 1IFOBBAIIOI
•) fiaronna, U, 6 aaaplea
b) Jacaay City. BJ, 5 Maples
c) Pittsburgh. PA, 12 saaplss
d) Batoa Boaga, LI, 10 saaplas
a) Charlaaton, BT, 9 saaplsa
f) Total a)-a)
Dos to saall aaapla siza and
BODcandoa smspling, data cannot ba
aztrapolated to antire population
Study naasorad anTironaantal
pollutants in ailk, evaluated using
ailk in pollutant studies near
chasieal aanofactoring plants and/or
indaatrlal lacilitias. Additional
data, U.S. and foreign, ratiauad.
For additional inforaation contact
BnTiconnantal Protaction agancr,
Bxposura Evaluation Division, Office
of Toxic Substances, Washington, DC
20*61
Lactating volnntaars, residing in
arum >12 so, no travel oat of area
during preceding *k
IODISIAIA; BEB JEBSET; PBi.STtfAlIA;
BEST TIBBIBIA; ADOtTS; BILK]
BEASOBEBEBT BEXBODS; BBBSEBBS;
CBXOBIIATED BTDBOCABBOBS;
CB10BOBEBSBBBS; DDE; IBDOSTBUL
ABEAS; IBDOSTBIA1 BBISSIOBS;
LACTATIOB; PESTICIDE RESIDDBS; OBBAB
ABE1S; XBDOSTBIAI. CHEHICALS; SOLTEBTS
BBFEBEICE
Erickson, a.D.
Barris, B.S.B.. Ill
Palliszari, B.D.
Tonar, K.B.
Haddell, B.D.
Bhitakar, D.A.
1980
EPA 560/13-89-029. 153
pp.
-------
Beiaene, dichloco-
25321-22-6
C6-H»-C12
HI 147.01, BP 173-180 C
TISSOB
3
Rilk
— - -
EXPOSOBB BOOTS'"
V,
-v.'X.
* Ti
;*' r; '
BBTHOD
OC/HS
in i •
— -
•URBBB
3F CASES
42
URCB
a) 0.2-66 nq/ml
b) 0.9-66 ng/nl
c\ 0.2-8.9 aq/al
d) 0.2-44 ng/al
e) 0.0«-26 nq/sl
f) 0.04-68 nq/al
___
BEAB
a) 19.37 »or- 25. Sit
ng/al
b) 24. *8 or- 31.69
nj/al
c) 1.71 »oc- 2.41
ng/al
d) 8 »ac- 13.98 ng/Bl
e) ». 30 »sr- 8.25
ng/al
f( 9. 15 *oc- 17.3
ng/al
SBBBBit IBPORHlTIOB
a) Bavoaae, BJ, 6 saaple*
b) Jersey City. "J, 5 saiplea
c) Pltt«burqb. PA, U saipl««
d) Baton Boage. LI, 10 aaiples
e) Ch«rlB«ton, VI. 9 saiples
f| total a)-*)
DM to Mail MI pic size and
noncando* sampling, data cannot be
extrapolated to entire population
Study minted ea*lroniental
pollutants in ailk, eralnated using
nilk la pollutant studies Ticlnitf of
cheelcal Mnofactaclnq plants and/or
indaatcial facilities, kdditional
data, 0.3. and foreign, reviewed.
For additional Information contact
BnfltonaeDtai Protection igency.
Ezposoce Evaluation Division, Office
of Toxic Substances, lashington, DC
20*61
Lactatiag volunteers, residing in
area >12 10, no travel oat of area
daring preceding vk
tODISHVl; NN JEBSEI; PEIISUT1IIA;
VEST TliCIIIHj 1DDLT5; BZtK;
HEISOBEHBII BBTBODS; BBKBBBSt
CBlOBIIlTED BTDBOClBBOBSi
CBIABOBEIZBIBS; DDBj IIDDSIBIIL
iBMS; IBDDSTBItl BBISSIOBS;
UCTMIOB; PBSTICZDB BBSIDDBS; OBB1I
ABBiSl ZBDOSTRIlL CBBHICUS: SOLTBITS
REPEBEBCE
Erlckson, N.D.
Harris, B.S.H., III
Pellizzari, E.D.
Toner, K.8.
Baddell, P.D.
Whi taker, D.I.
1980
EPt 560/13-80-029, 1-S3
pp.
Benzene, bexachloro-
C6-C16
HI 28*. 80, BP 231 C. BP 323-326 C, TP I •• Bg at II*. a c
IISSOB
«
Bilk
J,
s
•ilk
BIPOSOBB BOOTS
-
- -
..
tlaLITIClI.
BBTBOD
TL:
oc
GC
BOBBEB
3P CkSBS
a) 59
b) IS
cl 97
BaBCB
a) 1.0-17 agAg
b) 2.4-31 agAg
e} 1.4-7.2 ag/kg
a) 9.0-10-7 ppb
b) 3.7-4.1 ppb
BBaB
at 4.0 agAg
b) 6.3 agAg
c) 3. 3 agAg
a) Bot given
b) B>t given
(BBXT PaGB)
6BBBBU IBPOBB1TIOB
a) Bov 1971-Dec 1972
b) Jane-IOT 1974
c) Bar 1976-flar 1977
Bach case represents a pooled sanple
fro* 10-20 aothers.
Sasples f ron nosen in Stockhols,
Sweden
PESTICIDES; S1EDEII HIKj BIPBEITL
COBPOOBDS; CBLOBIBB OB61BIC
COBPOOBDS; CBLOBOBBBSBBBS;
P01TCBLOBIB4TBD BIPBEBILS; DIELDBII;
DDT: DDE; BEUCBLOSOCICLOBEXtlE
a) Saaple 1
b) Sample 2
Repeated deterainations
PBSTICIDBSs CBLOBOBBBSBBES; DDES BILK
BBFEBE1CE
Bestoo, 6.
Bores, K.
1978
labio 7(2) :62-64
Brevik, B.B.
1978
Bulletin of
BaTiroaaeatal
Contaaination and
Toxicology 19:281-286
-------
Bensene, hexachloro-
118-74-1
C6-C16
BB 281.80, HP 231 C. BP 323-326 C, vp I •• Bg at 114.4 C
(COBTIIOBD)
TISSUE
6
•ilk
7
•ilk
8
Bilk
9
•ilk
—
EXPOSURE ROOTE
ARALTTICAL
BETHOD
GC
CC/BS
8C-BC
OC/H3
6C-BC
RUBBER
DF CASES
2
•1 10
b) 25
c) 35
d) 10
e) 20
f) lot
given
10
a| 14
b) It
e) 10
d) 9
HUGE
0.09-0.23 ug
a) lot given
b) Bot given
c) lot given
d) lot given
•) BOt given
C) 1-21 ng/g
1.6-17.1 agAg
a) Mot given
b) Bot given
c) Bot given
d) Bot given
' ' " TiBxf
HEAR
0. 16 ug
•I 1 ng/g
b| 1 ng/g
c) 2 ng/g
d) 1 ng/g
•) * ng/g
f) 2 »g/g
5.9 ag/kg
a) 5.5 » sc - 3.7
ag/kg
b) 9.2 » or - 4.0
ag/kg
o) 2.7 » oc - 1.0
ag/kg
d) 3.2 » oc - 1.2
ag/kg
PAGE)
GEEERAL IBPOBBHIOB
iBoanta varied foe dilfetant
feedings. Values ace daily total.
Sanples f con donon at vacions tin*s
of bceast feeding and at different
tines of the day.
BILK; PESTICIDES; PESTICIDE RESIDUES;
MITCBIORIB1TED BIPBEBTLS;
BIOaCCDHOLUIOB; BEUCBLOBOBEBZEBE:
DDT; BKUCBLOROCfCLOHEXalB;
BEPT1CHLOR BPOXIOE; OXTCBLORDtiE;
BOB1CBLOR; DDE; DIBLORIB
a) Eastern Canada '
b) Quebec
c) Ontario
d) Central Canada
e) lestecn Canada
f) Rational average, sanples above 1
ng/g
Rational Surrey, 1975
BiraiRTL COBWOBDS; UBaDl; CBLORIRE
ORG1IIC CORPOORDS; DDE; DDT;
DIELDRIR; BEPTACBtOR EPOXIOE;
BBIICBLOROBBRIBBE;
•BUCBLOBOCTCtOBEXaBEi BILK;
•OBaCBlOR; OEtCBLORDME; PESTICIDES;
niICBIOBIB»BD BIPBEHILS:
MUCBLOBIBftTED TERPBEBTLS
tactatiag nothecs
17-41 yc olds fron Slavonia Province,
Yugoslavia.
TDOOSuna; UCTitlOR; BUK;
BZOkCCDBOlHIOBt lORal aBBaS;
CBZOIIBaTED B1DROC4RBOBS; CBLORIRB
OR6IRIC COBPOORDS; CBLOROBERtEIBS;
DDE; ODI; BEXtCHlOROCtClOBEXlRB;
PESTICIDES
a) Oslo, large industrialised city
b) Bergen, large ladnstcialisad city
c) Bars tad, snaller city witk large
chenical/petrochenical conplex
d) Porsgroan, non-industrlaliied
fishing connnnity
1976 sarvey. Significant difference
(P < 0.05) betveen saspling sites;
Bergen > Oslo > Hacstad, Poragrun
Honegiaa nothers, ages 25-26 yr.
ADIPOSE TISSOE; BILK; COBPUHIfB
BVU01TIOBS; RORRU; aDOLTS;
AUTOPSIES; BBRBORI; CHLOBIRATBD
BTDROCaBBORS; DDT; PESTICIDES;
POnCHLORIBaTED BIPBBBTLS
REFERBRCE
Res, J.
Da vies, D.J.
1976
Cbenosphere
7 (9): 699-706
Bes, J.
Davies, D.J.
1979
Bulletin of
Environmental
Contnninntion and
Toxicology 21:381-387
Kodcic-Snit, a.
Snit, z.
Olie, R.
1980
Pesticides Ronitoring
Journal 14(1) :1-2
Brevik, E.B.
Bjerk, J.B.
1978
Acta Pharnacologica at
Toxicologica
43(1)959-63
-------
Benzene, hexachloro-
118-74-1
C6-C16
B» 28*.80. at 231 C. BP 323-326 C. vp 1 .. Hg at IU.4 c
TISSOE
10
Bilk
11
Bilk
12
Bilk
13
Bilk, fat
14
Bilk.
viol*
BXPOSDBE BOOTE
»
ABAtTtlCAL ~~
BBTBOO
GC
1
GC-EC
GC-BC
GC-EC
ioBBBi"
OF CASES
14
50
'.,
Li.
ai 21
b) 24
c| 45
33
22
(CONIIHOED)
BABGE
0-0.25 ppn
18-63 ppb
a) 0.161-10.388 pp»
b) 1.146-9.445 pp»
c) 0.161-10.388 ppi
Trace-5.13 ppi
0.012-0.034 pp>
NEAI
0. 10 ppi
•0 ppb
a) 3.735 »or- 0.69*
ppi
b) 3.322 »or- 0.528
ppi
c| 3.515 or- 0.«25
ppi
0.091 ppi
0.025 ppi
GEIEBAL IBPOBBATIOII
Collected ID 1973, 1974
Ontario residents, ieao age 24 jc.
IBDOSTBIAL CBEfllCALS; CAIADA; ICE;
AUTOPSIES; ADIPOSE TISSUE; HILK;
CBLOBIBE OHGAIIC COHPOD1DS;
CBLOBOBBIZEVES; DDT; OIELDBII;
BBXACBLOBOBE1ZEIIE; PESTICIDES;
POLICHLOB MATED BIPBEITLS; PESTICIDE
RESIDDESj POPOL1TIOI EXPOSOBE
Extracted lipids. Jan 1979 to Peb
1980, 3-46 days poatpartui. lo
significant correlation «ith
reaideoca, age, weight, naiber of
children previously nursed, household
use of non-persistent pesticides, or
occupation of spouse. Higher, bat
nonsignificant levels in voaen vith
higher frequency of ieat conniption,
and in those in hoaea with pest
control treatient.
Healthy 18-37 yr old Hanalins
ADDITS; AGE; Bii»II; SILK;
CBLOBHtTED BIDBOCiBBOIS; DDE; DDT;
DIELDBII; BEUCB10BOCIC10BBXUE;
BEPT1CBLOB BPOXIDE;
BBXiCBLOBOBBIEEIEt LI»D»IE;
•OlaCBLOBt OXZCBLOBDklE; PESTICIDES;
POIICBLOBIIITBD BIPBBITLS; DIETS;
UCT1TIOI; PESTICIDE BESIDOES;
POPOlaTIOl BXPOSOBE
a) Boral residents
b) Ocban residents
c) Coablned, rural and urban
residents
Spain
SPUI; BILK; COHPiBiTITE ETaUUTIOIS;
P010ICIDES; BEXaCBLOBOBEIZElE; HElltH
BaUBDS; POPOLITIOI EZPOSOBB; BOBtL
1BE1S; OBBtM 1BE1S
1977-1978 study
Patients at public health offices,
alberta, 17-309 days postpartni. 24
voien lived in Bdaooton.
BILK; PESTICIDES;
BEXaCBLOBOCICLOBEXllE; ODD; DDE; DDT;
DIZLDBIB; BBPTkCBLOB BPOXIDE;
BEUCBLOBOBEBZEBB: ClIlDt;
POHCBXOBIIaTED BIPBBBTIS;
COBPaBATIVE BfALOKIOBS
Survey, Hestern Australia, 1970-1971
22 nursing lothers, «t 46-66 kg,
living Kithln a 30 si radios of
Perth, Bestern Australia
BIU; PESTICIDES; AOSTBAIIA; DDT;
DDE; DIEtDBIB; BBXACBXOBOBBlZBlB
BEfEBEBCE
Holdrinet, fl.T.B.
Brann, H. E.
Prank, B.
Stopps, G.J.
Sioat, M.S.
flcvade, J.«.
1977
Canadian Journal of
Public Health 66:74-80
Takahashi. v.
Saidin, D.
Takel, G.
Bong. L.
1981
Bulletin of
Environmental
Contaiination and
Toxicology 27:506-511
Polo Tillar, L.B.
Berrera Harteache, A.
PozoLora, B.
Lopez Oinenez, B.
Jodral Tillarejo, a.
Iglesias Perez, J.
1979
Bevista Espanola de
Pediatria
35(207-208):271-274
Carrie, B.A.
Kadis, T.B.
Breitkreitz, ».E.
Cunninghai, G.B.
Brans, G.I.
1979
Pesticides Bonitorlig
Journal 13 (2): 52-55
Stacey. C.I.
Thoias, B.B.
1975
Pesticides Bonitoring
Journal 9 (2): 64-66
-------
Benzene, pentachloro-
608-93-5
C6-H-C15
BB 250.3», HP 86 C, BP 277 C
TXSSOB
IS
Bilk
ZXPOSORE BOOTE
1ULTTIC1L
1BTBOO
GC-EC
GC/BS
B0BBEB
OF CUES
BilGE
0-3.1 ng/kg
HE* I
2.0 ug/kg
GEIEBAL HPOBBATIOH
Lactnting aethers
17-41 ic olds froa slavoain Province.
Yugoslavia.
LACTATIOB; BILK;
BIOACCOBOLATIOI; BOBAL ABBAS;
CBLOBIBATED BIDBOCABBOVS; CBLOHIBE
OBGABIC COBPOOBDS; CBLOBOBEBZERES;
DDB; ODI: BEUCHLOBOCICLOBEXUE;
PESTICIDES
REFBBSHCS
Kodric-Ssit. a.
Slit, Z.
Olie. It.
1980
Pesticides Bonitoring
Journal 1«(1) :1-2
Benzenesnlfonaaide, 2-chloro-5-(l-hydroxy-3-oxo-t-isoindollnyl)- (6 CI|
Benzenasilfounide. 2-chlato-S-(2. 3-dihydco-l-hydrory-3-o«o-1B-i«oindol-l-yU- (9 CI)
77-36-1
CU-HII-Cl-«2-0»-S
Bl 338.78, BP 22*-226 C (deconp)
TISSOE
16
Bilk
EXPOSOBE BODTB
Ingeetion
- -
tllLTIICll
HBIBOD
ac-BC
_
•OBBEB
OF CASES
7
0.09-0
BUGB
BEiB
0.37 ag/al
BBBEBtL IIFOBNHXOB
•anen with toxenia of pregnancy.
Values 3 days alter delivery.
DBWSl CBLOBIBB OBG1BIC COBPOOIOS)
DXOBRICS; PUCEBTki FBECIAICT;
DBBXLXCat COBD; BILK; BLOOD: tBBXOTXC
FtBIO
8EFEBEICE
Bailey. B.I.
Pare, G.D.
Pan, B.I.
Bye, B.fl.
Boeld, J.J.
Siddle, B.C.
1978
European Journal of
Clinical Pharmacology
13:129-131
BBC, Total (Bo post lag a in CBBBLIBE).
BB 290.85
TISSUE
17
Bilk
18
Bilk
EXPOSOBE BOOTE
GC
1 of 51
BABCE
a) 1.7-V5.5 ppb
b) lot given
c) Bot given
lot given
RBAB
a) 9.«« ppb
b) 12.8 ppb
C) 6.8 ppb
0.003 ppn
GBBBBA1 XBFOBBATXOB
a) All saaples
b) Colostme
c) 9-16 «k after birtfc of infant
Bilk saaples, hospitals la urban
Oslo. * •aaples fcon Ballingdal, a
valley in southern lorvay. Bo
occupational exposure.
BXIB; IBSECTICIDES; LACTATIOB;
CBLOBIBATED BIDBOCABBOBS; CBIOBII8
OBOARXC COBPOOBDSt PESTICIDES; BOB8AI
Bandoa subjects of greater St. Louis.
BO. Mtcopolitan area. Talnes are
total of alpha, beta, and delta
liadane.
PESTICIDES; CBLOBIBE OBGAIIC
COBPOOBDS; DDT: DDE; DXELDBXBl
BBXACBLOBOCTCLOBEXABB: BBPIACBLOB
EPoxiDE: BILK: aissooti: COBPABATITB
BVALOATIOBS
BEPEBEBCE
Bakkea, l.F.
Seip, fl.
1976
Acta Paediatrica
Seandlnavica 65:535-539
Jonsson, T.
Lin, G.J.I.
Ambraster, J.
Kattelhat, L.I.
Or acker, B.
1977
Anerican Journal of
Clinical Bntritioa
30:1106-1109
(BBXT PAGE)
-------
P08tln'8 ln
(COITIIOBD)
TISSDB
19
•ilk
20
Bilk
21
•ilk.
•hole
'YDAQIIDB Drtltw
C&rU9UHfi BODTE
AEALYTICAL
HBTBOD
K
t
GC
GC
TIC
IOBBBB
OP CASES
a) 27
b) 9
c| 10
4) 40
SO
25
BARGE
a) 0-0.019 ppi
b) 0-0.057 ppi
c) 0.010-0.035 ppi
d) 0.00 1-0. OHO ppi
0-480 ppb
0.0326-0.2384 ppi
mi
a) 0.006 ppi
b) O.OIS pp.
c) 0.024 ppi
d) 0.012 ppa
86 ppb
0. 1077 »oc- 1.0124
ppi
S.B.
GE»mi IBFOBBATIOR
a) Cotton, coCDt and sesase-groviag
area
b) Corn and cotton area
c) Coco acea
d) Coffee-groMing area. El Salvador
a)-c) IB Guatemala. Highest use of
pesticides on cotton.
Bothers fros lov-incoie faiill«s in
Goataiala and Bl Salvador, areas
chosen to ce present different degrees
of use of pesticides.
Overuse of pesticides a particular
p rob lea in tropical countries.
Prevalence of aalnutrition aav
contribute to health effects.
iGBICDLIOBE; CHLOBIIB OBGIKIC
COBPOO»DS: CHOP ODSTIBG; DDT;
DIELOBII; BL SALT1DOB; FOOD
CORlRXBaTIOV} GDKBULA;
BBXiCUOBOCTClOBEXtlE; BBPT1CBLOB
BPOIIDEt IISECTXCXDES; BILK;
BOTBITXOItt DEFICIEICIES; PESTICtDBS;
PESTICIDE BBSIDOES
BJttracted lipids. Jan 1979 to Feb
1980, 3-46 day* postpartui. BO
significant correlation residence.
age. Height, nuiber of children
previousli lursed, household use of
ooo persistent pesticides, or
occupation of spouse. Big her, bat
nonsignificant levels in voien with
higher frequency of Beat consumption.
and in those living in hoses treated
by pest control operators
Bealthy 18-37 yc old HaMaiiaas
aDDLTS; ICE; Hi»AII; NILKl
CBLOBIIaTED BIOBOC1BBOBS} DDE; DDU
DIELDBII; BBUCBLOBOCTCLOBBZUE;
HEPTACHLOB BEOZIDZ;
BEUCBLOBODBBZEBE; LIBDtBB;
ICMCHlOBj OZTCBLOBDUE; PESTICIDES;
P01TCBLOBIB1TED BIPBEBILS; DIETS;
LaCTktIOl; PESTICIDE BESIDOBS;
POPDLKIOI EZPOSDBE
-
24 he after parturition
19-35 yr old sothars, no history of
exposure to pesticides. India
DOC; DOB; DDT; BEXaCBLOBOCTCLOBEXIf B;
LIBDklE; aiOACCOBOLATIOE; PESTICIDE
BESIOOES; BLOOD; BILK; IIDIA; A DDL IS;
BEUOSB
BEFEBBICZ
de Caipos, H.
Olszyna-Haczys, A.E.
1979
Archives of
Environiental
Coataiination and
Toxicologr 8:43-58
Takahashl. u.
Saidin, D.
Takei, G.
Bong. l.
1981
Bulletin of
Enrlrosiental
Contamination and
toxicology 27:506-511
Siddigal. B.K.J.
Saxena. B.C.
Bhargava, A. 1C.
Seth. T.D.
Krishna Burti, C.B.
Kutty. D.
1981
Environmental Besearch
24:24-32
-------
Bipheayl, chloco (6 CI)'
t,1'-Biph«nyl, chloco derive (9 CI)
1336-36-3
BHCt COBFOSITIOI OBM01N OB OIDETEBBIIIED
TISSOE
22
Basiary
gland
23
Bilk
24
Bilk
25
Bilk
BIPOSOBE BOOTS
Xngestion
ANALYTICAL
SETHOD
CC
GC-EC
TLC
GC
CC
NOHBEB
OF CASES
a» 5
bl 9
c| 9
I. 119
b) 59
c) t5
d) 97
BANGS
a) 2.38-3.92 ppi
b) 4.34-11.25 ppi
c) l.33-«.2« ppi
>ot given
a) 10-20 ug/kg
b) 20-40 aq/kg
c) 10-30 ag/kg
d) 20-40 og/kg
1.17-1.77 ug
NBA II
a) 2.9849 ppi
b) 9. 1430 ppi
c) 2.7680 ppi
0.093 ppi
a) 14 ag/kg
b) 26 ugAg
c) 24 ag/kg
d) 30 ag/kg
1.47 ug
CEIERAL IIFOBRATIOX
a) Control
b) Balignaat
c) Breast tissue adjacent to
•alignaacy
Values represent the concentrations
in extracted lipids.
BaUgnant tissue, adjacent to
apparently noraal glandular and
adipose tissue of nine voien nit*
adeoocarcinow of the breast.
obtained fros the i.e. Canargo
Hospital in Sao Paulo. Baniarr gland
and adjacent adipose tisane fron $
healthy vosen vho died accidentally
used Cor controls.
BE EAST; BARBABI CLAUDS; BBOPLASRS;
ADIPOSE TISSDE; CAECIIOHAS;
PESTICIDES; LIPIDS: CBLOBIBaTED
HTDiOCABBOIS; CHIOBINB OBG1IIC
COHPOOIDS; BIOACCOHOLATIOK; BIPBBIIL
COBPOOB05; OIELOBII; POLICHLOBIIATED
BIPBEIIIS; DOT; DDE;
HBUCBLOBOCICLOBEUBE; 000;
BBPTtCBLOB EPOIIDE
70 cases had values greater than 0.10
ppi.
Saiples troi narsing lathers in
hospitals in 45 states
CHIOBIIB OBGMIC COBPOOBDS; nFABTS;
POOO COItaBIUTIOB; BILK; BIHHABt
OL1BD3
a) Apr-July 1967
b) Bo* 1971-Dec 1972
c) Juae-BOf 1974
d) Bar 1976-nar 1977
Bach case represents a pooled saiple
froi 10-20 lotheri.
Saiples froi noiei in Stockhole,
Svedei
PESTICIDES; SIBDBB; HIIK; BIPBEIIL
COBPOOBDS; CBLOBIIB OBGAIIC
COBPOOBOS; CBLOBOBBBZBBBS;
POIICHLOBIIATED BIPBBIILS; DIELDBIB;
DDT; ODB; BBUCBLOBOCICLOBBXUE
Aaounts varied for different
feedings. Values are daily total.
Sasples froi donors at various tines
of breast feeding and at different
tins of the day.
BILK; PESTICIDES; PESTICIDE HBSIDOBS;
POLTCBLOBIBITBD BIPBBBTLS;
BIOACCOBOLATION; BBIACBLOBOBEIZEBE;
DDT; BEXACBLOBOCTCLOBBXAIE;
BBPTaCBLOB BPOXIDB; OXICBLOBDIBB;
BOIICBLOB; DDE; DIBLDBIB
(BBXT P1GBI
FEFEBERCE
lasseriann, N.
logueira, D.p
Toiatis, L.
Blrra. A.P.
Shibata, R.
Arie, C.
Cucos, s.
Hasseriann, D,
1976
Bulletin of
Enviroanental
Contaiination
Toxicology
15 (4): 478-484
and
Anon
1978a
Cheaical Begulation
Beporter 2(24):9
U1
lestoo, G.
Boren, K.
1978
Albio 7(2) :62-64
Bes. J.
Davies, D.J.
1978
Cheaosphare
7(9):699-706
-------
Biphenyl, chloco (8 Cl)
1,1«-Biph«iyl, chloro derlvs (9 cl)
1336*36** 3
BMCT COHPOSniOV OBKBOBE OR OBDBTEBBIBBD
(COBTIIOED)
TISSDE
26 '
•1U
27
Bilk
28
Bilk
29
Bilk
30
Bilk
EXPOSURE BOOtB
•
IIlLTTICiL
BBTBOD
GC
GC
--
GC/BS
OC
IOBBBB
OP C1SBS
29
a) 40
b) 38
c| 19
d| 20
a) 19
•1 10
b) 25
c| 35
d| 10
•) 20
f) lot
given
17
BINGE
lot given
a) Bot given
b) Bot gUen
e) Bot given
d) Bot givan
•) lot givan
«) Bot givan
b) Bot givan
c) Bot givan
d) Bot givan
a) Bot givan
t) 1-68 ng/g
a) Bot given
b| Bot given
e) Bot given
d) Bot givan
/
/
BEaB
0.0««2 pps
a) 2.* ppn,
b) 2.4 ppa,
c) 3.2 ppa,
d) 2.0 ppa.
a) 1.8 ppi.
a| 8 ng/g
b) 10 ng/g
c| 17 ng/g
d) 8 ag/g
e) 15 ng/g
1C) 12 ng/g
a) 612. 5 ppl
b| 680.0 pp)
C) 482.5 ppl
d) 530.0 ppl
Fat basis
" / (BHt P1BB)
fat basis
GEBEB1L IBPOBBaTIOB
Bigber percentages of organochlorine
insecticides and PCS'* in silk of
•others 20-29 raars than 10-39.
although the forner had lover levels
in plassa. Overweight nosen had
lover levels thaa VOMB of aornal
Height. Besidnes concentrated in
attracted llpids of plasia and ailk.
Israeli voaen 2-« days after norsal
delivery.
PESTICIDES; BLOOD PLISBA; BILK;
FOPOLaTIOB EXPOSUBE; ISRAEL;
CHLOBII4IKD HIDBOCIBBOKSJ LI PI OS;
iOI; DOT; ODD; DDE; POLICBLOBIBITBD
BIPBBBILS; BEPtlCRLOB BPOIIDB;
BntCBLOBOCTCLOBIXtlE
a) 1973
b) 197«
1975
1976
a) 1977
Estimated fro* graph
Bothers in Osaka prefectare
BIPBBBTL COBPOOBDSi C8LOBIBB OROillC
COBPODBDSl DDE; DDT; DXELDBIB;
BBUCBLOBOCICI.OBBZaBB; JIPaB; BILK;
POLTCBLOBIBaTSD BIPBEBTLS
a) Eastern Canada
b) Quebec
c) Ontario
d) Central Canada
a) Bastera Canada
C) latiooal average, sasple* above I
•9/4
flaasored as arochlor 1260
Bational Sarrer. 1975
BUBBBTL COBPOOBDS; CkBlDa; CBLOBIBB
OBGaBIC COBPOOBDS; DDE; DDT;
DIELDBII; BBPTtCBLOB EP01IOB;
BBUCnoBOBBBCEBB;
BBZlCBLOBOCiaOBBZiBE: BUI;
IOHCBLOB; onCBLOBDtBB: PESTICIDES;
MIYCBLOBIBaTED BIPBEBTLS;
POLICBLOBIBATED TEBPBEBTLS
Baviav
BEVIEB; POLICBLOBIBITED BIPHBIIL3;
BITSB POLIDTIOB; POPOLUIOB BXPOSDBB;
aZB POLIOTIOB; BBUTB BU1BDS;
C1BCIBOGBB; BILK
a) I sonth
b) 2 sonths
cj 5 souths
4) 7 souths
after partnritloa in 1977. EstUated
(cos graph.
Boraal, pregnant voaen la Japan.
P01ICBLOBIBUBD BIPBEBILS) BBBBOBBl
pBEOBtici; jmi; BLOOD; BILK;
UCTUIOB
Polishak, l.V.
Bon, N.
Bassereann, .1.
Cucos, s.
Vasseraana, D.
lesesch, C.
1977
Pesticides Bonitoring
Journal 10 (t): 121-129
Xaknsbijl. T.
Batanabe, I.
Kuvabara, K.
loshida, S.
Bori. S.
Pnkushisa. s.
Kashiaoto. T.
Royaaa, K.
Kunita, B.
1979
Archives of
BavironBental
CoataBinatioa and
Toxicology 8s59-66
Baa, J.
Davies, D.J.
1979
Bulletin of
Environmental
Contaaination and
Toxicology 21:381-387
Ol
Bayle, B.B.
Bighlaad, J.B.
1979
Boviroaeent
21(5)16-13,37.38
Kodasa, B.
Ota, B.
1980
archives of
Environmental Health
35(2X95-100
-------
Biphanrlt chloro (8 CX|
I.t'-Biphenyl, chloro derivs (9 ci)
1336-36-3
EX1CI COH POSITION DIKHOBI 08 OBDBiEBHIBED
(COITIIOBD)
TISSUE
, -
31
Hilk
32
•ilk
33
Hilk
.
34
•ilk
35
Bilk
'
BXPOSOBB BOOT!
AIALYTICAL
BBIBOD
OC-EC
GC
nc
oc
•OBBBB
OF CUBS
a) 14
b| II
c) 10
d) 9
8
1,057
«) 43
b) 3«
e| 19
RUGB
•) not given
b) Hot given
c) lot given
d) lot given
<0.04-0.l ppn
•) Tr«ce-5.100 ppn
b) 0-< 1 ppn
e) 1-< 2 ppn
d) 2-< 3 ppn
e) > 3 ppn
Fnt Kt basin
a) 0.7-1.2 ppn
b) 0.2-3.0 ppn
c) 0.1-2.5 ppn
(•EXT
mi
a) 24 * or -
b) 2» » oc -
c) 29 » or -
d) 19 » oc -
0.05 pp»
a) 1.496 ppn
b) Rot given
cj lot given
d| lot given
ej lot given
Pat »t bails
a) 1.0 ppn
b) 1.2 ppn
c) 1.2 ppn
PUB)
- ng/kg
- 8 ngAg
GEIERAL XMFOBBATIOI
a) Oslo, large industrialized city
b) Bergen, large industrialized city
c) Barstad, smaller city Kith large
chenleal/petroehenical conplex
d) Porsgronn, Bon-industrialized
fishing eonnonitr
1976 survey. Significant increase (P
< 0.05) in Oslo, Bergen, and Barstad
sasples coaparad to a 1969/70 survey.
Bonegian nothers, ages 25-28 yr.
ADIPOSE TISSUE! BILK] COBPARATITE
BVALOATIOIS; BORBAI; ADULTS;
AUTOPSIES; BERBOBBs DOT; CHLORIIAtBD
HTDROCARBOIS; PESTICIDES;
POLXCHLOBIIATED BIPHEBIIS
Beviev of biological inpact of PCBs
on breast-fed infants and
ceconnendatlona for noraiag nothers
JAPAB; ADULTS; IBFARS; SKII
DISUSES; HIIK: BEVIEl;
POLTBBOHII1TBD BIPBBIILS;
KIICBXOBIBATBD BIPBBIILS;
BIOlCCOHOlaTIOBi FIRE EHTtBDilTS;
POOD co»a»B»ioB; NODS; LICTAIIOB;
MPOUTXOI EXPOSOIE
Higkest 2 levels in honseviven «ho
bad never lived oatside Colorado.
19-26 yc olds in 2 Colorado
coaauitles nitfc popalatlona of abont
•3.000, prinarlly agricnltoral, light
industry.
COLORADO; ADOLI5; BILK;
POItCBLOBIIAXED BIPREBXLS; POPDLATIOB
BXPOSOBE; BUBAL ABBAS
a) Total, 1977-1978
b) 27S of sanples
c) «9.5* of saaples
d) 17.»« of sasples
e) 6.IX of sanples
Besideats of Blchigan
BICHIOAB; ADULTS; BILK;
POLTCHLOBIBATED BIPBBBTLS; flBALTB
BAXABDS; IBDDSIBIAL AREAS
a) 1969-70
b) 1971-72
c) 1973-7*
Sanpling periods
Level of exposure unkoova
Ontario residents, nean age 24-28 yr.
IBDOSTBIAL CBBHICALS: CAIADA; ABB;
AUTOPSIES; ADIPOSE TISSUE; BILK;
CHLORIIB OBGABIC COBPOOIDS;
CBLOROBEIIBIES; DOT: DIELDBII;
BBXACBLOROBBBZBIE; PESTICIDES;
POLICBLOBIBATED BIPBEBILS; PESTICIDE
RESIDUES; POPOLATIOH BIPOSOB!
BBFBBBBCB
Brevik, E.N.
Bjeck, J.B.
1978 .
Acta Phacnacologica et
Toxicologica
43(1) :59-63
fllller, B.M.
Finberg, L.
1977
Journal of Pediatrics
90(31:510-512
Savage, E.P.
Tessari, J.D.
Balberg. J.I.
•heeler, B.I.
1973
Bulletin of
Baviroanental
Contamination and
Toxicology 9 (4): 222-226
•ickiier, T.B.
Brilliant, L.B.
Copeland, B.
Tildea, R.
1981
Anerican Journal of
Pablic Health
71 (2): 132-137
Boldrlnet. B.T.B.
Brnan, B.I.
Prank, B.
Stopps, G.J.
Saout, B.S.
Bclade, J.i.
1977
Canadian Journal of
Pablic Bealth 68:74-80
-------
Blpkenyl, chloco (0 CI)
I.l'-Blphenyl, chloro dad** |9 CX)
1336—36—3
EXACT COBPOSXIXOR 01KIMK OB OSDETEBBIHED
(CO»riHDBD)
tISSDE
36
Bilk
37
•ilk
38
Bilk
39
Bilk
KfOSOBE ROOTS
Ingestion
i
ARAlYtXCAl
METHOD
GC/BS
„_„_„_ »_,_,_,.
OC-8C
ROBBER
or cists
80
1
IS«
RARGE
»| lot given
b) Not given
lot applicable
a) 0-9. 3 > eg/kg Cat
b) lot given
c) lot given
„.._„„,„
""" ™™m (I2XI
SBAH
a| 1.80 pp«
b) 2.64 pp«
62« 1. 1 ppb
a) 0.837 »or- 0.529
•g/kg Cat
b) 0.59 tor- 0.32
•g/kg fat
c) O.S6 »oc- 0.40
•g/kg Cat
'
P»G!)
a) til sabjecta, fco> II states
b) north Carolina resident*, state
Hitb highest aeaa
stadias b; D.S. Environmental
Protection igencv
•OETH CliOtI»»; UNITED STATES; MILK;
POIICHLOBIKITED BIPHEKItS
PCB norkec
37 yr old Japanese
tDOLTS; tDTOPSIES; CRILDBEN;
DISEiSBS; 401 POSE TISSOE;
BLOOD; I»TESTI»ES; LIVES; milt;
COHP»E»TI»E BHLOH108S: CHLOEIBE
OSGKIC COBPODKOS: POLTCHlORIHiTED
BXP82IU5; POITCHLOKI»»TED
QO»TEBPHE»T13; FOOD COBTIBIB1TIOH:
HZILTH HaZlBBS
a) 153 saiple*, 0.029 tor- 0.019
•g/kg vhole «ilk
b) Rural residents, 19 *a*plea
c) Orban resident*. 51 saiples
3-6 days postpartna. b) and c)
signifies Dtly different. Positive
correlation vith age. 93X exceeded
the OSa acceptable daily intake.
18-38 yr old*. Canada
ClHDii tOE; BILK; DDE: DDT;
CBLOBIIE OB6MXC COHMOIDS;
HBZaCBLOIlOCICLOBIUIE; LXIDllE;
POLICBLOBIIiTED BIPBE1TLS; POPOL1IIOII
BIPOSDBE; BOR1L 1BE*S; SNOKXIG; OBB4S
IBEtS
Review
BecoiBeodation* for breast lilk
testing and infant feeding sade
following discovery of PCBs in breast
•ilk of Bichigan residents.
tDOLTS; xmns; BILK; BEfXEl;
CBLORX1E OBGaNIC COBPODRDS:
POLICBLOIXMTED BIPBEVILS; BE*LTB
BaSAROS; UCTATXOR; alCHIGM
BEfEBEBCE
anon
1977C
Pollution 7(1) :6
Ptashi.oto, T.
liyata, H.
Kunlta, I.
1981
Food and Cosaetica
Toxicology I9:335-3«0
Billon, J.C.
Battle, G.B.
O'Erten, fl.T.
1981
Food and Cosaetics
Toxicology l9:«37-»«2
00
•ickizer, T.B.
Brilliant, L.8.
1981
Pediatrics
68(3>:411-UI5
-------
Blphen;!, chloEo (8 CI)
I.l'-Biphenyl, chlaro dsrivs (9 CI)
1336-36-3
EXACT COBPOSXTIO* OBIMOHI OR 01IDET2BHIBED
(COBTIHDED)
TISSUE
»0
•ilk
81
Bilk
•2
Bilk, f*t
«3
•ilk, fat
EXPOSDBS BOOT!
AIALYT1CAL
METHOD
/US
-1C
HOBBEB
OF C»SBS
SO
I
52
33
BANSE
16-1800 ppb
—
a) 6.6-8.6 ng/q
b) 578-607 ng/g
30-870 ppb
lot d»tectable-0.7SI ppa
BEAU
780 ppb
a) lot given
b) B»t given
350 ppb
0.085 ppl
GEKEBAL mrOBKATXOI
Extracted lipids, Jan 1979 to Feb
1980, 3-116 days postpactoa. No
significant correlation uith
resilience, age, ueight, nuib«r o£
children prerlously nursed, household
use of oon persistent pesticides, oc
occupation of spouse. Higher, but
nonsignificant levels in woaen with
and in those in homes with pest
control treatment.
Healthy 18-37 yr old Baxaiians
»DDLTS; AGE; HUB. 11; BILK;
CBLORXIaTSD BIDSOCAEBOIS; ODE; DDT;
DIZLDBII; HEUCHLOEOCICLOHEI»«E;
BEPTACdLOB IPOIIDE;
BEXaCBlOIOBERZElB; LIlDAlC;
•CWICHLOB; OIICRLOBDiBE; PESTICIDES;
EOIICBLOBIK1TED BUBBITLS; DIETS;
L1CT1TI01; tESTICIOE BESIDOES;
POPOL»TIO« BIPOSBSE
a) Ihole silk
b) rat
aange foe *-6 OTtcaction techniques.
Of total by lit in ailk, *-10( tras
trichlorobiphenyl, 15-28)1
tetcachlocobipbenyl, 10-161
pectachlocobiphenyl, 12-13*
herachlocobiphenyl, 27-«9«
heptacblocobiphenyl, and 7-9f
ootachlotoblphenyl
IIOOSIBIlt CBEBIC4LS; CilaOI; iDBLTS;
BILK; RBaSHBHEIT BETHODS; r»Si
POIICHlOBIilTED BUBEIfLS
Bothecs of 2-12 ao old infants
Baalthy aothers f roa Karme, Japan
and their breast fed infants (2-12 «o
old).
PESTICIDES: POLICHLOBIHTED
BIPHEITLS; BIPBEin COBMOIDSi
CHLOBIBE OBOlBlC COBPOOIIDS; ID I POSE
TISSOE; ADBEIAL GUBDS; BLOOD; LITER;
HILIC; ADULTS; XiralTS; fETDS; J4P»«
1977-1978 study
Patients at public health offices.
Alberta, 17-309 days postpactna. 21
uocen lived in tdsooton.
MILK; PESTICIDES!
BKACBLOBOCICLOHEIAME; ODD; DDE; DDT;
DIELDBII; HEPTACBIOB EPOIIDB;
HEIACBLOBOBEIZEBB; C1XADA;
POLICBLOEIIATED BIPBESYLS;
COBPABATITE ETAIBATIOHS
PEFEEENCE
Takahashi, I.
Saidin, D.
takei, G.
Wong, L.
1981
Bulletin of
Environaental
Contaaination and
Res, J.
Davies, D.J.
Lao, P.-T.
1980
Cheaosphere 9:763-769
Basuda, X.
Kagava, B.
Kuroki, B.
Kuratsune, n.
foshisura, T.
Takl, I.
Rasuda, a.
Xaaasbita, f.
Hayasni, >.
1978
Food and Cosaetics
Toxicology 16:S43-S«6
Curcie, B.A.
Kadis, *.«.
Bceitkceiti, B.E.
Cnnnicghaa, S.B.
Bcuns, 0. H.
1979
pesticides Bonitocing
Journal 13(21:52-55
" " """ """ (NEXT PAGE)
CO
-------
Bipaenyl, chloco (6 ci)
!sU"fip5*B!rlf ckloro a«i»« o CD
•3jo~36"3
BliCT COHPCsmOl OHRIOHI OB OBDEtEBRIEBD
(COITIEOED)
TISSUE
«*
Hi Ik
•hole
45
Hllk,
•hole
•6
Bilk.
•hole
4XPOSOBB BODTB
*
Ingest ion
BETHOD
GC-BC
GC
- —- .-
GC-BC
•OHBBB
OP CASES
57
52
•UIGE
Trace
,
1-36 ppb
a) 0.01-0.10 ppi
b) lot given
c) lot given
d) 0.01-0. U pps
a) 0.01-0. 10 ppi
f) 0.01-0.2* ppi
RE'AB
13 ppb
a) 0.032 » oc - 0.019
PP«
b) 0.038 * oc - 0.025
ppi
c) 0.0«0 » oc - 0.026
ppi
d) 0.036 » or - 0.023
ppa
•) 0.033 » oc - 0.017
ppi
f) 0.039 » oc - 0.02
ppi
GEREEAL IIFOBHATIOI
Saaples fro* 17 Keg toes and «0
caacaiiaaa in hospitals in Arkansas
and Hisstssippi.
PESTICIDES; PESTICIDE BE5IDOES; BILK;
BIOlCCOROLaTIOl; POPOLATIOH EZPOSOEE;
flaBRABI 6L1KDS; L»CT»TIO»: PLlCBVTli
tBKilSIS; BISSISSIPPI
Hothtcs of 2-12 so old infanta.
Expressed as total illk.
Baaltkr lothats Ccoi Kacaia, Japan
and their bcwst fed infants (2-12 so
old).
PESTICIDES; POLICBLOBI BATED
BIPBEBTLS] BIPHBItt COBPODBDS;
CHLOBIIE OBCUIC COHMOBDS; ADIPOSE
TISSUE; ADBENAL 61ABDS; BLOOD; LITEB;
BIU; ADULTS; I IF AITS; FETUS; JAPAI
a) 1972, Ml saaplea
b) 1973, 123 saaples
c) 1974, 119 saaples
d) 1975. 113 saaplea
•) 1976, 100 saaples
2) 1977, 101 sa spies
Levels highest in 1st parity Bothers.
100- Ul lactating vosan, 2 sontbs
attar dalivary. Besidents of Osaka
Prefectace, Japan, varied diets and
eiTironsental conditions.
JAPAI; LACTATIOI; BLOOD; BILK;
BIOACCOBDLATIOB; PESTICIDES;
FOLICBLOBI1ATED BIPBEBILS; OBGABIC
CBLOBIBE COBPODBDS
KEFEBEVCE
Strasssan, S.c.
Kutr, F.v.
1977
Pesticides Nonitorlng
Journal 10(«) : 130-133
Rasoda, T.
Kagava, P.
Knroki, N.
Kuratsone, i.
loshiiora, T.
Taki, I.
Knsoda, a.
Tasashita, F.
Bayashi, B.
1978
Food and Cosaetics
Toxicologr !6:5«3-Sa«
Taknsbiji. T.
latanabe, I.
Knwabaca, K.
Tosbida, S.
Koyaaa, K.
Kanita, I.
1979
International Archives
of Occupational and
En*ironiental Health
•3:1-15
Cadiiae
7««0-«3-9
Cd
At! 112.40, RP 321 C, BP 765 C, fp 1 is Bg at 394 C, 10 as Bg at 486 C
TISSUE
47
Bilk
EIPOSOBE BOOTS
Ingestion
_
1BAITTICAL
BBTHOD
- -
BOBBBB
OF CASES
„ ,, . „.
BABGE
BBAB
GBREBAL IIFOBBATIOI
Bevieii. profile of healthy subjects.
Baseline data Cor detecainlng changes
in nutritional status froi indostrlal
food processing techniques.
BBI ZBALABD; ADULTS; FBTOS; IIFAITS;
BLOOD SEBOB; BAIB; KIDRETS; UTEB;
BILK; BEVIES; DIETS; FOODS; SOILS;
T8GBTATIOB; CADBIOR; COPPBB;
BABGABBSE; BBTALS; TBACE ELBBBRTS;
IMC
BEFEBBICE
Gathrie, B.B.
Bobinson, 8.F.
1978
lev Zealand Bedical
Journal 87(603X3-8
-------
Caffeine (8 CI>
1B-Parine-2,6-4ione, 3,7-dihjdro-l, 3.7-triaethf 1- (9 CI)
58-08-2
C8-B 10-14-02
HI.194.19, HP 238 C
TISSUE
«8
Bilk
ET.P050BE BOOTE
mLTTICAL
HBTBOD
-
HM.C
or
as
IOHBEB
OF C.SES
28
B»GE
<0.5-4.S Bg/1
.
HE»H
Nat given
GEIEBaL XIFOBRHIOI
M
Only 6 of 28 •••pies exceeded
detectable aidants of > or » 0.5
•9/l>
28 randoa saiples
PB1ICE; Cal«Dl; TEEOPBTLLIIBS; DBDGS;
OBOO THEBaPI; IIFAITS; ADOLTS; BLOOD;
BLOOD PUSBI; COBPlBaTXfE
BfaLOlTIOIS; LOIGSi HBTaBOLXTES;
IEHBOBI; IEOBOHOSCOL1B DISEASES;
CiFFEIlE; OBBILICtL COBD
BEFEREBCE
Botj, C.
Baltasaat, P.
Porthaalt, B.
Bathenod. r.
Fcedeclcb, A.
Icanda, J.v.
1979
Journal of Pudiatrlcs
9«(6) :988-993
Calciu
7ea0-70-2
Ca
at« 40.08. HP 850 C, BP 1MO C, TP 10 •• Rg at 983 C
TISSUE
•9
•ilk
50
Hilk
BXPOSOBB BODTE
1 MLTTIC1L
HBTBOD
iaS
ES
IOHBEB
OF CaSBS
,,
a) 28
b) 39
C| 23
i) 13
•1 28
(I 30
BAIGE
a) lot giYOB
b) lot gi»en
c) lot given
d) lot given
•) lot given
f) lot given
lot given
HBtl
- --
a) 257 » or •
ag/ai
b) 236 « oc •
ng/Bl
e) 175 * oc •
ag/al
d) 170 * oc •
09/1!
•) 196 » oc
ag/al
f) ISO * oc
ag/al
29 oc- 2.3
GBIBBIL IIFOBHaTIOl
a) 1-3 ao lactation
b) •-« ao lactation
c) 7-9 ao lactation
d) 10-12 ao lactation
•) 13-18 ao lactation
f) 19-31 ao lactation
•hit* »oa«n, !9-*2 vc age, 22
pcialpacae.
BLOOD SBBOB; BILK; BBTaLSt LiCTlTIOI;
BUI! CaLCIOBi BaOIBSIOBl HalGIIBSB;
I Ml; COPPEB; IIIC
Bilk fcoa aothera of 12 pcetaca and 2
Ion birth Mt infanta, or fcoa Baaaa
Hilk Bucaau, St. David's Boapital,
Cardiff, «al«a
OIITBD UIGDOR; ZIFalTS; lOTUTIOIIL
DBFICIEICIBS; BILK; OBIIE; CU.CIOB;
DIETS
BEFEBEICE
Taaghant L.l.
••bee. C.I.
Keabacliag, S.B.
1979
taecican Journal of
Clinical late it ion
32:2301-2306
Shan. J.C.L.
1976
Pedlatcica 57 (1|! 16-25
N>
-------
Chlordane
12789-03-6
C10-H6-C18
BB «09.8. DP 175 C at 2 •• Hg, TP 1X10(8-5) •• Hg at 25 C
TISSUE
51
Bilk
BXPOSOU BOOTB
IngeitiOQ
AIALTTICAL
HBTBOD
or
IDHBEB
OF CASES
a) 21
b) 2«
c) US
d) «S
BAIGE
a) 0-0. ISO ppi
b) 0-0.723 ppi
c) 0-0.723 ppi
d) Bot given
HEM
a) 0.0IS ppi
b) 0.026 ppi
c) 0.026 ppi
d) 0.0003 ppi
GEIEBAL IIPOBBATIOI
a) Bural nothers, fat basis
b) Urban nothers, fat basis
c) All Bothers, fat basis
d) All nothers, vhole silk basis
Data for ana of all pesticides and
comparisons Kith values of other
investigators given
luraing nothers fron Cordoba region.
Spain
SPAII; ADULTS; MILK; CHLOBIIE OBG1IIC
COBPOOIDS; PESTICIDES; AGBICOLTOBE;
BUBAL ABBAS; DBBAB ABBAS
SEFIRBNCB
Pozo Lora. B.
Becrerd Barteache, A.
Polo Vlllar, L.H.
Lopez-?iaenez, R.
Jodcal villarejo, II.
Iglesias Perez, J.
1979
Bevista Espanola de
Pediatria
35(206) :93-110
Chlorofora (8 CI)
Be thane. tri.chloro- (9 ci)
67-66-3
C-H-C13
Bl 119.39, BP -63.5 C. IP 100 •• Bg at 10.» C
TXSSDE I
1
52
Bilk
BXPOSOBE BOOIB
4HLIIIC1L
BBTBOD
GC/BS
BOBBEB
OP CASKS
•2
UBOB
a) Bot detected-1.3 09/1!
b) 1.7-65 ag/sl
e) 0.6-6.7 ng/il
d) 0.3-21 ng/al
e) 5.0-12 ng/Ml
C) lot detect»d-65 ng/il
BEII
a) 0.52 tor- 0.«8
ng/el
b) 23.3« or- 2«.3
ng/el
c) 1.S3 »or- l.7«
ng/el
d| 3.09 «or- 6.3«
ng/il
e) 7.21 *or- 3.55
ng/il
f| 5.57 «or- 10.9
ng/el
6EIBUL XIPOIBATIOB
•) Baronne, U, 6 saiples
b) Jersey City, IJ. 5 sasples
c) Pittsborgh. PI, 12 saeples
d) Baton Boige, 11, 10 saiples
e) Chacleston. If, 9 saeples
f| total a)-e)
Dae to siall caiple size and
aonrandoi saipling, data cannot be
extrapolated to entire popalation
StadT leasared entriconiental
pollutants la illk, evaluated aaing
•ilk in pollutant stadias near
cheaical nanofaetoring plants and/or
industrial facilities. Additional
data, O.s. and foreign, reviewed.
For additional information contact
Environmental Protection Agency.
Exposure Evaluation Division, Office
of toxic Substances, lashington, DC
20*61
lactating volunteers, residing in
area >12 so, no travel out of area
during preceding *k
LOOISIAIA; IN JBBSBI; PBIBSTLTAHA;
•ESI TIBGIIIA: ADULTS; BILK;
BEASOBEBEIT (IBTBODS; BBIZBIES;
CBLOBII1TBD BTDBOCABBOIS;
CBLOBOBEBSEBBS; DOB; IIDOSTBI1L
ABB1S] IIOOStBIAL BBISSIOIS;
LACTAtlOl; PESTICIDE BB3XDOES; OBBAI
ABEASl XIOOStBIAL CBEBXC11S; SOtTEITS
BBFBBEICE
Erickson, B.D.
Barris. B.S.B.. Ill
Pellizzari, E.D.
Toner, IC.B.
Vaadell, B.D.
Bbitnker, D.A.
1980
EPA 560/13-80-029.
PP-
153
-------
CbTOBiUS
7««0-«7-3
Cc
ItB 51.996. HP 1900 C, BP 26*2 C, fP I •• fig at 1616 C, 10 •• 89 at 1B«0 C
TISSUE
53
Ulk
54
Bilk
EXPOSOBB BOOH
'
Ingest ion
AE1LITIC1L
HETBOO
115
US ,
IONBEB
OF CASES
.^
'
a) 5
b» 5
BU61
a) 0.23-0.66 ni
b) 0. 14-0.45 a
c) 0.19-0.69 D
d) 0.13-0.44 a
a) 0.19-0.69 0
b) 0.24-0.54 a
nil
a) 0.43 » or - 0.13
ng/al
b) 0.27 » or - 0.10
ag/day
c) 0.39 * or - 0.21
ng/nl
d) 0.26 * or - 0.14
ag/day
a) 0.39 ag/al
b) 0.34 ag/Bl
GBIEB1L IIFOBH1TIOI
-
a) 10 Bothers, 8-18 days lactation
b) 10 Infants. 8-18 days old
c) 5 Bothers, 47-54 days lactation
d) 5 infants. 47-54 days old
Mothers and their breast-fed infants
in Finland.
Bill; LICTITIOK; flMLllO; CBKOBIUH;
BEtlLS; CODP1R1TIVB EflLOaTXOIS;
IIF1ITS
a) 6 to 8 iik postpartas
b) 17 to 22 Mk post par tua
Bean saternal dietary intake, 31
ag/day. lo correlation with breast
silk.
Lactating Fianisa Bothers
CHBOBIOBi BET1LS; BIOICCOBOLITIOI;
DIRS; FOOD COIT1HI1TXOI: L1CT1TXOI;
aiLK| FIltllD
REFEBEICE |
Kaspolainen. J.
fuorl. E.
1980
aserican Journal of
Clinical nutrition
33:2299-2302
Kaapnlainen. J.
vnori, E.
Rakinan, S.
Kara, B.
1980
British Joarnal of
Nutrition 4*: 257-263
Copper
7MO-SO-8
Co
»ti 63.5*6, BP 1083 C, BP 2S9S C, TP 1 •• Bg at 1628 C, 10 BB Bg at 1870 C
XIS5DB
55
•ilk
«
56
•ilk
_ ._
EIPOSOBB BOOTE
'
, -
-'
1I1LTIIC11
HETBOD
IIS
US
•OBBBI
OF CUBS
SO
a) 28
b| 39
e| 23
d) 13
e) 28
fl 30
BaBGE
0.09-0.63 ug/nl
lot given
lot giren
lot given
d) lot given
e) lot given
f) lot given
•Ell
0.24 ag/al
a) 0.43 » or - O.OS
ag/al
b) 0.33 » or - 0.03
ng/al
c) 0.30 » or - 0.03
ag/al
d) 0.24 » or - 0.04
og/al
e) 0.29 » or - 0.08
og/«l
f) 0.28 » or - 0.06
ag/nl
OEIBIll IirOBRHIOl
analysis of variance indicates that
several saaples taken over periods of
days and weeks are necessary to
famish a reliable estiaate of C«
content foran iadivldaal.
Sasples froB Pennsylvania Bothers.
42 subjects vere between the ages of
20 and 30, vhile 8 were over 30.
all subjects had healthy, fall-tern
infants.
COPPBB; IBOIJ ZIK; BBtllSt MIBUlSj
BBTlBOLISRf L1CT1IIOI; DIETS; RIUs
IBRBOBl! PBIISTLT1II1
a) 1-3 ao lactation
b) 4-6 ao lactation
c) 7-9 BO lactation
d) 10-12 aonths lactation
e) 13-18 BO lactation
f) 19-31 BO lactation
Ihite vonen, 19-42 yr age, 22
prlBiparae and 16 saltiparae, 1-31 ac
postpartoa.
BLOOD SBBOB; BILK; BETllS; L1CI1T10I;
HUB; CILCIOB; BIOIESIDBJ UKIIBSEI
IBOli COPPER} SIBC
BBFEBBICB
Picciano, H.F.
Gothrie, B.I.
1976
•sericaa Joarnal of
Clinical latrltioB
29:242-254
faaghan, L.l.
leber. C.I.
Reaberling, S.B.
1979
laeriean Joarnal of
Clinical latrltion
32(2301-2306
(IBIT PaOB)
-------
Copper
7*40-50-8
Co
AM 63.5*6. HP 1083 C. BP 2595 C. It I •• 89 at 1628 C, 10 •• Bg at 1870 C
(COITIROED)
TISSUE
57
Bilk
SB
Bilk
59
Bilk
EXPOSDBB SOOTH
9
Ingest ion
ARALTTICAL
SETHOD
AAS
•
ROBBER
OP CISBS
a) 76
b) 77
0 23
i| 77
•) 25
BARGE
a) lot given
b) lot. given
c) lot given
d) lot given
•) Rot given
BEAI
0.«6 ng/ai
0.29 ug/il
c) 0. 16 ng/*l
d) 0.29 ug/al
a) 0.36 ug/*l
6EIISAI. IiroBIUTZOI
a) Colostru*. high and lo« IOCOM
groups
b) llt«t lactation 1-3 eonth*, higk
and Ion inco*e group*
c) After lactation > or • 13 noaths.
high and Ion incoae group*
d) After lactation 1-3 souths, lo*
incoae group
e) liter lactation 1-3 *oaths. high
incoae gcoap
Significant difference (P3.«>5>6-hexachl3CO-. (1alph«,2»lpha,3bet«,K«lph«,5bat«.6bata| - (9 CI)
319-8»-6
C6-H6-C16
BB 290.83, at 159.5-160 C. BP 288 C. »P 0.02 •• Hg at 20 C
IISSOE
60
Bilk
EXPOSOBB BOOTS
BBTHOD
TLS
GC
RORBEB
OP CASES
a) 59
b| 15
c| 97
BARGE
a) Rot given
b) Rot given
c) Rot given
(HEII
BEAI
a) <0.25 ngAg
b) <0.25 ngAg
c) <0.25 ngAg
PISE)
GBIBBA1 IHPOEHATIOI
a) lov 1971-Dec 1972
b) June-Rov 197*
c) Bnr 1976-Har 1977
Bach case represents a pooled sasple
fro* 10-20 *other*.
Saaples f ros «o*en In Stockhol*.
Sveden
PESTICIDES; SBEDEI; BILK; BIPBBin
CORPOOIDS; CBLOBIIB ORGAIIC
COBPODIDS; CBLOBOBBIZBIBS;
POIICBLOBIMMED BIPBEIILS; DIELDBXI;
DOT; DDE! BEX1CBLOBOCICLOBBXUE
BBPEBEICE
lestoo, G.
lore*. K.
1978
Aablo 7(2):62-64
-------
Cyclohexane, 1.2,3,4,5,6-hexachloro-, alpha- (8 CI)
Cyclohexane, l,2.3,a,5,6-hsxachloro-, (lalpha,2alpha.3beta,aalpha.5beta.6bata)- (9 CD
C6-B6-C16
BB 290.83. BP 159.5-160 C, BP 28B C. TP 0.02 •> 89 at 20 C
fCONTIIOED)
TISSUE
61
Bilk
62
Bilk
£3
Bilk, fat
6«
Bilk, fat
65
Bilk, fat
.
EIFOSOII SOOTB
MU.TTIC1L
BETBOO
OC
nc
.__ _.,,.
OC-BC
OC/HS
6C-BC
.
6C-BC
,
10 HBER
OF C1SES
IT
s
a) 53
b) 33
a) 3D
b| 6
BilCE
0.1-1.9 ppb
< 0.1 agAg
-
lot gl*aa
a) lot detectable-0.733
ppa
b) lot detectable-0.016
ppa
a) 0-0.27 ppa
b) 0-0.01 ppa
DEI*
O.S8 ppb
Nat applicable
0. 12 a9/k9
a) 0.107 ppa
b) 0.002 ppa
a) 0.02 ppa
b) 0.003 ppa
ti
I
GEHEBAL HFOBBATIOI
Bilk sasplea. hospitals In urban
Oalo. • aaaplas fcoa Ballingdal, a
valley in southern HOCK*7. Ho
occupational exposur*.
BILK; IISECTXCXDESt LiCTMXOI;
CBXOIXEaTBO BXOBOC1BBOIS; CBIOBIIE
OBG1IXC COBPOIIIDS: PESTICIDES; IOBH1I
LactatiB9 aothers
17-si it olds Ccoa Sla«onia Pco*iace,
Tagoslavia.
TOGOStlTIl; UCTlTIOl; BILK;
BIOaCCDBOLaTIOl; RDBtL IIBIS;
CBLOBXIaTED BTOBOCAKBOIS; CBLOBIIB
OBGaBIC COBPOOIDS; CBLOBOBEIZEIES;
DDE; DDt; HEXiCHLOBOCTCtOHEIilE;
PBSflCIDBS
85 saapl«a-«ack la avacaga tcoa 20
aothara. Bilk obtalaafl Ccoa lactacla
IB Slovakia. 1971-1973. Taluaa
•atlaatai fcoa graph.
PESTICIDES; BILK; raTS)
CIECBOSIO«KI»J
BBMCBLOBOCTCLOBEI1IE; DOT: DOB;
BBUCBIOBOBBIZBIE
a) 1966-1970 study
b) 1977-1978 study
1966-70 patients. (Oniversity of
alberta Hospital), 2-10 days
postpartus. 1977-78 patleata (public
health offices of alberta), 17-309
days postpartua. Besideaces, Edaoaton
or alberta.
BI1K; PESTICIDES;
BEUCBLOIOCyCLOBIIalB; DDD; DDE; DDT;
DIUDBIl; BEPMCBLOB BPOKDE;
BEXaCBLOIOBEIIIIE; CUaDai
PO1TCBLOBXI1TED BXPBEITIS)
COBPiBaTIIE ETtLPHIOIS
a) Bigb pesticide usage area
b) lov pesticide usage area
loaen liTlng la Stark*illa,
Bissisalppl (lo« pesticide usage) aad
Delta area (high peatlcide usage).
Saaplea la 1973-1975.
BILK; PESTICIDES; DDE; DDD; DDT;
BBHCHLOBOCTCLOBEIKB; BEPT1CB10B
EPOIXDBl OXXCBLOBDABE; DIBIDIII;
BISSISSIPPI; COBPIBaTIVB BTllOaTIOIS;
BBaSOIEBBIT BBTBODS
BEFEEEICB
Bakken. A.F.
Seip. B.
1976
acta Pavdiatrica
Scandinaflca 65:5J5-539
Kodric-Sait. II.
Salt, Z.
Olie, K.
1980
Pesticides HoaitoriD9
Journal It (I): 1-2
Szokolay. a.
Boslval. L.
Ohnak. J.
Badaric. t.
1977
Icotoslcology and
Bnvlronaental Safi
1:3*9-359
Safety
Carrie. B.a.
Kadis, T.I.
Braitkreitx, I.E.
Coaningfcaa, G.B.
Brans, 6.1.
1979
Pesticides Bonitoriag
Journal 13 (2): 52-55
Baraett, B.I.
D'Brcole, a.J.
Cain. J.D.
trthnr. B.D.
1979
Pesticides Bonitoring
Journal 13 (2):« 7-51
-------
Cycloaeiane. 1,2.3.a.5.6-hexachloro-. beta- (8 CI)
CTClohexane. l,],3.a.5,6-hexachloro-. (Ulpha,2bata,3alpha.abata,5alpl>a.6beta| - (9
C6-B6-CU
nw 290.83, RP 3M-315 C (snbllees) , B? 60 C at 0.58 •• B«. TP 0.005 •• 89 at 20 C
TISSUE
66
Bilk
67
Bilk
•8
811k
69
Bilk
70
8Uk
IIMSDU IOOTB
%
aULTTiciL
RETROD
TU
ec
6C
- -
6C
tic
cc
I08BII
OP CJLSSS
a) 59
b| IS
e| 97
2
57
• 9
•I 23
b) 20
c) 12
d| »0
•) 38
f» 19
91 20
h) 19
E*IGB
• ) 0.7-21 BgAq
b) 1.7-5.7 nq/kg
c) 1.9-7.7 aq/kq
0.07-0.10 ag
trace-O.OI PPB
1.2-17.8 ppb
a) Bot given
b) Bot given
c) Bot given
d| lot given
•) Bat given
f) Bot given
q) Bot given
k) Bot given
(•SIT
BEtB
«( 6.« aq/kq
b) 3.6 sg/kq
c) 3.8 ag/kq
0.09 a]
2-6«
Res. J.
Defies, O.J.
1978
Chesospkere
7(9) : 699-706
(Btz. F.B.
Strassaaa, S.C.
Tobs, k.B.
1976
International Rorkshop
OB Biological Speclsea
Collection, tprll.
1976. Lozeaboarg
Bakkea. ».F.
Selp. R.
1976
Icta Paedlatrlca
ScaBdlaa*lca 65:535-539
zaknskljl. T.
Ratanabe, I.
Ennabara. K.
Toshlda. S.
florl. S.
Fakaskiaa, S.
KasklBOto, T.
Koyasa, B.
Malta, 1.
1979
archives of
Envlronseatal
Coataalnatlon and
Toxicology 8:59-66
-------
Cvclokexane. l,2,3.«.5.6-kexackloro-. beta- (8 CI)
Crclokaxane. 1.2,3.«.S,6-kexackloco-, (1«lpnn.2bota,3alpka.«bata,5alpka,6beta|- (9 CI|
C6-B6-C16
Bl 290.83. HP 3I«-315 C (aabllBM), at 60 C at 0.58 aa Rg. TP 0.005 aa H
-------
Ciclokazaa*. l,2.3.»,5.6-k*zackloro-. Data- (8 ci)
CTCloaetan.. 1,l.l.«.3,C-kanckloro-. (1alpka.2bata.3alpka.«bata,5«lplia.6bata)- (9 CH
319-85-7
C6-BC-C16
n MO. 83, BP 3K-3IS C (aabliaaat, 3P 60 C »t 0.58 • » 19. TP O.OOS »• Bg at 20 C
(COITII>E3)
TISSBE
It
Ulk, fat
77
Bilk.
•aol*
78
Bilk.
•koto
EIPOSORE nn<
IttLTTXCaL
1ST BOD
SC-BC
GC-EC
n:
ec/Bs
ec-K
IDBBEI
OP CaSBS
57
57
UtCE
a) lot givaa
b) lot gi*aa
c) lot giTaa
41 lot glvaa
•1 lot giTaa
f) lot gi*aa
Traca-0.01 ppa
Traca-0.01 ppa
at«i
a| a.B3 • ar - 2.99
ppa
b) 3.25 .or - 1.59
PP»
e| «.S» • at - 2.73
PC"
4) «.78 « 3t - 2.«5
pp.
«) 3. 10 » or - 1.51
pp*
f) 2.«7 « or - 1.00
ft*
0.01* ppi
<0.01 pp«
CEISttL IlfOiBlTIOI
•) 1972, »0 uaplci
b) 1973. 38 c*Bpl*s
c) 197* , 19 l»pl*«
4) 1975. 20 tuples
•) 1976. 19 suplos
f) 1977. 20 mpUs
100- Ul lact*tl>9 COMB. 2 aoatks
*(t«r dclinry. l««id»t* of Osaka
Pnf«ct*r«. J«p*», ««ri«4 4i«t« aid
••TiromM »tal co*4ltiou.
JaPil; 1DILTS; LICT1TIOI; BIL»;
BIOaCCIBILtTIOl ; PESTICIOBS; OtCMIC
CBIOUIB COBPOCIDS; POLICILOUI1TEB
BXMMTLS
l»«14»« !•*•!• ••» b*lo« ia*tr«M&t
•nmlUvitT and coald »ot b*
eotflrtH«.
SMplas f ro> 17 l«gro«« aad *0
CMCKBiBB* la koapitals ia ackamsas
ui «i«»i»»ippi.
rasnczns: PESTICIDE BBSIMES; am:
BHkiocnrL4Tioi; MMUTIOI BSPOS«IE:
BAHMT 6UIDS; LICTUIOI: PLaCEKa:
UUBSaS; BISSZSSIPPI
36.81 pOSlUt* MBplM
Saipl** froa lactatiag wo*«* i>
••lactat ac«as of ickamsas aad
Bi«aimmippi.
PBSTICIOES; UIPOSE tXSSOI; BILK:
tint; Biotccnn.aTioi: Btmrn.
couoan; CBLOSIUTIB mtoattois:
uciBsas; BISSISSIPPI
tifCTticr
Tataxaiji. T.
lataaaDc, I.
(••atara. I.
losiida, S.
Eoyaaa, «.
(aiita. 1.
1979
iBteraatioaai itd>i»cs
of Ocopatloaal aa4
EBTirouaatal Bcaltk
•3s 1-15
Stcama&aa, S.c.
Intl. r.i.
1977
Puticlo** Boaltoclaj
Joanal 10 («l : 130-133
latz, P.I.
Stra«»»aa, S.C.
lobs. a.l.
1977
Pacticid* Baaagnaat
u4 Iaa«cticioa
•••istaac*. Ica4aaic
Pcoaa. lac.. ••• lock.
Saa Praaciaca. Ioa4oa,
(BP. S23-S39J
CycloaazaM. 1,2.3.a.5.6-k«xachloro-, 4«lta- (8 :q
CTCloaaxaaa. l.2.3.«.S.6-a«uckloco-. |1alpka.2alpka.3alpka.«b*ta,5alpha.6l»tal - (9
CE-M-CU
0> MO.83. BP UI.S-U2.0 C. BP 60 C at 0.3* aa Bg. IP 0.02 aa Eg at 20 C
Ttssn
19
Bilk
izposnt torn
4U1TTIOL
IITBOD
sc
nc
BBBBEI
OP Casts
3*
tllCE
0.3-3.2 ppb
(IEIT
nil
l.ia ppb
PISE)
CERaal KPOIBinol
Bilk aaaplaa, aoapitala ia arbaa
Oalo. a aaaplaa ftoa lalliagdal. a
nlla? la aoataara Boraay. lo
occmpatioaal axpoaara.
BILK: BIBaST; IBSimcniS;
UCTAXIOl: CBLMintU BTIBOCaUOIS:
OLOBIII
-------
CTclokaxaa*. l.2.3.*.S.6-kaxackloro-, dalta- ft CD
Cjclokcxaoc. 1.2.3.«.S.6-kancklaco-, |1alpka.2alpk*.3alBht.*bata.Salpka.6bata)- (9 CD
319-86-6
C6-M-C16
•I 290.03. a? 1*1.5-1*2.0 C, BP 60 C »t 0.3* u 19. »p 0.02 aa Bg at 20 C
TXSSOZ
80
•ilk, (at
EIPOS8EE BOBTC
1
1
BBTBOO
-
•BBBU
or cases
SilCE
Bot gi*«a
IE* I
0.10 ag/kg
,
CEBEBU. XBFOBB1TZOB
BS «aa|>l«a-*ack i* a*ora«o (COB 20
aetaara. Bilk obtaiaad (FOB lactaria
IB Slovakia. 1971-1973. falaas
•stlaatad froa grapk.
pesucuss; alii: PITS:
csEcaosiovaEii;
BBIaCBtOBOCTCLOBmBB; BDT; BOB:
BBUCSlOfOBEIIEl B
EEPEieic:
SzokolaT. >.
Bosiral. I.
Bkaak. J.
Badaric. ».
1977
Bcotoslcology aad
Eavlroaaaatal Sa£aty
1:3*9-359
5M9-9
!. l,2.3,*.S.6-kasacalx»ro^.
>. l.2.3.a.5.6-haxackloco-.
(8 CQ
- (9 CI)
cO Bj6~Tlt>
88 290.8S, B» gaaaa-iaoBor cryatals 112.S C. BP 323.* C. 176.2 C at 10 aa Bg. it 0.i* aa Bg at «0 C
1
1
81
olMd^
9£BMa
•2
•1U
•tTKkO
CC
SC-EC
TU
CC
or CASES
a. S
c| 9
a) 59
b| IS
c| 97
a| 0.19-0.81 ppa
b| 0.21-1.28 pp*
c) 0.10-2.57 PP*
a) Bat g-lvoB
b) Bot gl»a»
c) Bot gl*«
(IEIT
a) 0.3905 ppa
b) 0.6100 ppa
ct 0.5698 ppa
a) < or » O.S B9/kg
b| < or • 0.5 ag/kg
e) < or « 0.2 *9/kg
PiSE)
CIBBSU IBFOBUtXOI
a) coatrol
c} Bf**Bl tiavBo ad)ae*Bt to
•alias* acr
Talaaa rapraaaat tka coBcaBtcatioaa
la extracted It pi dm.
BaUgBaat tlawaa« adjaoaat to
appacoatlT auraal glaBdvlar aad
adiBoa* ti»««a of aiaa woaca altk
•flaBiiTBit lanaM of tka tcaaat.
obtBlBad (COB tao 4.C. CBBBKOB
aad ad)acaat adlooaa tlama (COB 5
baaltkr loaaa «ko dlad BecldOBtallr
aaad for coatrola.
BIBaSS; BAB8A8I 8UBBS: BBOPUSBS;
1BZPOSE TISSM; CUCZ808M;
PBSTXCIOES; 1IPI8S: CBtOBIBaTBB
•t88OCa8B08S; CHOBID OBUBIC
COBPOMBS: BXMCCOBBUtXOB: BIPUBTl
008PO8B8S: OtBlBBIB; POllCBlOBIBaTSB
BIPUBTLS; 8M; BM:
HZaCBIABOCTaOBEUBB: BBO;
BBUCnOB BPOXXBB
B) BO* I97I-BBC 1972
b) Jaao-BoT 197*
c) Bar 1976-Bar 1977
Back CBBO copraaaata * poolad aaapl*
(COB 10-20 BotkacB.
SBBplaa (COB la Stockkola,
PESTICIDES; StBHB; DtK: BIPBE1H
COBPOB1BS; CBtOBIIB O8UBIC
COBPOBBBS: CBMBOUUEBBS;
POUCBLOIH1TEB BirBBTLS; DIBUBIB;
BOT: BOB; 8BUC8U>BaCTCM8BX4BB
BBVBBBBCS
»t»aara»«a. B.
Bogaaira. 8.P.
toaatla. t.
Birra. ».P.
Skibata. B.
ad*, c.
Cvcos. S.
•BBavcaaaB. B.
1976
MUMtia o(
BaTlroaaaatal
1*Wxltxlfj1 xlxl^lfTn 1x1^1
Toxicolog)
15|*):<78-*8*
•aatoo. C.
fora*. I.
1978
lablo 7(2):62-6*
-------
CTCloharane, l.2,3.a,5,6-hexachloco-, qaaaa- (6 CI)
Crclohaxaoe. 1,2,3,1,5,6-hexachloro-, (1alpha.2alpha, 3beta,(alpha.5alpka.6betal - (9 CI)
5B-89-9
C6-B6-C16
•V 290.85. HP gaaaa-isoaer crystals 112.S C, 8P 323.« C, 176.2 C at 10 •• H«, TP 0.10 •• Bq at «0 C
(COITIIDED)
TISSOE
83
Bilk
8«
Bilk
85
Bilk
86
Bilk
EIPOSOBE BOOIE
*
'
Ingastion
iULTTICll
BETBOD
cc
oc
TIC
GC
OC
IUBBEI
OF CASES
2*
17
2 Of 51
•I 21
b) 2*
c| «5
d) 05
BalGE
lot giran
1.0-35.8 ppb
1
lot glTen
a) 0-0.061 ppi
b) 0-0.270 ppa
c) 0-0.270 ppi
d) lot gi»»n
NEal
0.0101 ppi
10.91 ppb
0.00* ppi
a) 0.01 1 ppa
b) 0.037 ppi
c) 0.025 pp>
d) O.OOOa ppi
GEIEEU. IirOCBITIOl
Blgher percentages of orgaaochlorlae
iBMctlcldc* and PCF's la all* of
aothaca 20-29 fears than 30-39.
althoogk the focier had lomr l«f«l»
IB plaaat. ot«r«*lqht >oian had
lov«c !•*•!• than «oi«n of nocul
wight. l«*idaaa coBcaatratcd la
•xtcactad llplda of plasaa and illk.
Israeli HOBCB 2-i day* after aoraal
deUvery.
PESTICIDES; BLOOD PLaSMi BILK;
POPOLUIOI HfOSOBE; ISB1EL;
CBLOIII1TBO BIDBOC1BBOIS; LIPIDS;
AGE; DDT; ODD; ODE; P01TCBLOUIHED
BIPBEIILS; BEPT1CHLOB BMXZDE;
BBUCBLOIOCICLOBmiE
Bilk uiplei, aocpltali IB acbaa
Oslo. » sacples fcoa Balllagdal, a
valley IB Soithern looaf. lo
occapatloul ecponce.
BUKl IISBCTICIDES; UCT1TXOI;
CBLOIIIaTBO BTDIOC1BMIS; CBU»IIB
OlSallC COBFOOIDS; PESTICIDES! lOBIal
Baodoi subjects of greater St. Louis.
BO. aetropolitan area.
PESTICIDES; CBtOIIIB OBGtUC
COBPODIDS; DDT; DOE; OIBLOBIll
BBXiCBLOBOCTClOBEUIE: BBPTtCBLOS
EPOIIDE; BIUl BISSOOII; COHPlBlTIfE
BfUDMIOIS
a) Baral aothers. Cat basis
b) Orbmn Bothers, fat basis
c) all aothera, fat basis
d) 111 aothera, nhole silk basis
Data foe sue of all peatlcldea aad
cosparlaons with raloas of other
IsTsatlgators given
larsiag aothers fcoa Cordoba region,
Spain
ID BITS; BIU; CBLOBIIE OBGIIIC
COIPOOIOS; PESTICIDES; 1CBICOLTOBI;
BOBaL »BE1S; OBBil ABIiS
tEFEDEICE
Pollshuk. ?..*.
Don, n.
Rasseraann, 1.
Coco*, S.
lasseriaan. D.
tcaesch. C.
1977
Pesticides lonltoriog
journal 10 (•): 121-129
Bakken, l.r.
seip, H.
1976
acta Paediatrlca
Scindina»lca 65:535-534
Jonsson, ».
Lia. O.J.It.
Inbrnster, J.
Kettelhnt, L.L.
oracker, B.
1977
leerican Journal of
Clinical lutrltloa
30:1106-1109
Pozo Lora, B.
Baccara lartaache, t.
polo Tillar, L.H.
topez-Glaanaz, B.
Jodral Tillare]o. n.
Iglaaias Perez, J.
1979
Bevista Bspanola de
pediatria
35(206):93-HO
-------
Cyclohaxane. l,2.3,*,S,6-kexackloro-, gaaaa- (8 CI)
CTClokexane, 1.2,3.«,S,6-kexackloro-. (1alpka,2alpha,3beta,«alpka,Snlpkt,6bota|- (9 CD
58-89-9
C6-H6-C16
HI 290.85, IP ganna-isoner crystals 112.5 C. IIP 323.* C, 176.2 C »t 10 •• Bg. fp 0.1* u Bg at «0 C
(COITIIOZD)
TISSUE
87
Bilk
88
Bilk. fat
89
Bilk, fat
90
Bilk. Cat
91
Bilk,
•koto
BTP030BE IOOTB
IHLTTIC1L
BBTBOD
OC-EC
SC-BC
CC-BC
GC
nc
BDBBEI
OF CISBS
IS*
•1 53
b) 33
•1 3*
b) 6
25
UIGE
a) 0-1.56 sg/kg f«
b) lot given
c) lot given
lot given
a) lot detectable-0.3*0
b) lot applicable
'
a) 0-0.29 ppa
b) 0-0.03 ppa
0.0106-0.810 PP«
•MI
at 0.0*7 »or- 0.131
ag/kg fat
b) 0.0* tor- 0.07
ng/kg fat
O 0.03 »or- 0.03
ng/kg fat
0.33 ag/kg
a) 0.006 ppa
b| lot detectable
a) 0.03 ppn
b| 0.008 ppn
0.0*02 «or- 0.0051
PPS
S.E.
GEIEIU, XIFOBIaTXOB
BEFEBEIC!
«) 0.002 »oc- 0.0001 eg/kg nkole I
•ilk, all sanples. 31 exceeded Units I
set by Codex llieaatarin* Consisslon I
b) Roral cesidenta, 19 sasples I
c) Ocbaa residents, 51 snsples I
3-6 dnys postpartoa. Previous breast I
feeding Inversely correlated vitk I
lindaae levels, lo correlation vltk I
age or place of residence I
I
18-38 yr olds, Canada I
ALOIXI: CMlOi; ME; HILI; CBLOHIE I
OH1IIC COBPODIDS; ODE; ODIi I
BBUCBIOIOCTCLOBEUIE; LIIC1IE; I
FOLTCBLOIIUTED BIFBEITL5; POPOtlTIOl |
EZMSOIE; BOBll ARElS; SBOHIC; OBBM I
»IElS I
I.
Dillon. J.C.
Bartln. C.B.
O'Brien. B.T.
1981
Food and Co»etlcs
Toxicology 19:O7-««2
85 sasples-eack is average froa 20
eotkera. Bilk obtained froa lactarla
la Slovakia, 1971-1973. Valnes
estiaated froa graph
PtSTXCXDBSl Mil: FITS;
CXBCBOSLOTalll:
BBUCB10IOCTCI«BnilEi DDT: DDE;
BBZACBMIOBBISBIE
I Szokolay. 1.
I Besival. L.
I Okaak. J.
I Badaric. ».
I 1977
I Bcotoxicology and
I Environmental Safety
I 1(3*9-359
a) 1966-1970 stady
b) 1977-1978 stady
19*6-70 patients (Oglverslty of
Ubertn Bospitali, 2-10 days
postpartan. 1977-78 patients (poblic
kealtk offices of klbertnl. 17-309
days postpartan. lesidences. Edsontan
or nlbertn.
BXLC; PESTICIDES;
BBUCBtOIOCiaOBEXilE; ODD; DDE] DO*;
DXELDBII; HBPTlCHtOB BPOIIDB;
BBUCBLOIOBBItBIE; CtllDt;
POUCBLOIXUTEO BXFBEITLS:
COIPlliTITE EVlLOtTIOIS
Carrie, l.l.
Kadis, T.I.
Breitkreltx, v.E.
Caaningban, G.B.
Brans, G.I.
1979
Pesticides Bonitocing
Joarnnl 13(2):52-55
CO
a) Blgk pesticide usage area
b) Lo* pesticide usage area
I Baraett, B.I.
I D'Brcole, l.J-
I Cain, J.D.
lonen living in starkvllle. I Irtkor, 1.0.
Blsslsslppi (lov pesticide nsage) and I 1979
Delta area (kigk pesticide nsage). I Pesticides lonitorlng
Sanplss in 1973-1975.
I Joaranl 13(2):»7-51
PESTICIDES; DDE; ODD: DDT:
BEiaCBLOiocicLoamiz: HEPTICBUJB
EPOIIDB; orlCHLOlDlIB; DXBLDBXIt
RXSSXSSXPPXl COBFiBtTXTZ BTatOltXOIS;
BE1SOBBBEIT HETBODS
2* kr after parturition
19-35 yr old aethers, no history of
exposore to pesticides. India
DDE; DDE; DDT; BBIlCHLOBOCIdOBEIllE;
E; BIOiCCOmillTIOl; PISTXCXDB
I Siddlgal, i.I.J.
I snxenn, B.C.
I Bkargava, l.K.
I Seth, T.D.
I Krishnn Barti, C.B.
I Batty, D.
I 1981
B.AB«Val*»t n«We»««*»i* «*"•»•»•—•—• -™— •— — .
• ESIDOBS; BLOOD; Bill: IIDI1; kDOLTS; I Bnvironnentnl Besenrch
HIBOII
2*:2*-32
-------
DDT. Total (Bo posting* In CHBRLIBE).
50-29-3
CII-B9-C15
BR 35*.SO
IISSOB
92
Bauary
gland
93
Baaaary
gland
EXPOSOBE BOOTH
ff
AB1LTTICAL
BETBOD
CC
GC-EC
CC
GC-EC
IORBER
OP CUES
«> 5
b| 9
c| 9
«) S
b| 9
01 9
RUSE
a) 8.29-18.30 PP.
b) a. 07-29. 39
c) 1.99-13.56 pps
a) 8.01-16.78 ppa
b) 1.8»-I2.38 ppa
c) 0.82-7.50 ppa
(»EXt
~BBAl
a) 12.4910 ppi
b) 13.5091 ppi
o) 6.3001 pp*
a) 11.5309 ppa
b) 7.4237 ppa
c) 3.9327 ppa
PISE)
(SEVERAL XRFOBBtTXOI
a) Control
b) Ballgnaat
c) Breast tissue adjacent to
saliguncy
Balignnnt tissue, adjacent to
apparently nocnal glandular and
adipose tlssM of nine noa«n Kith
adsaocarcinosa of the breastt
obtained fros the I.e. Casargo
Hospital In Sao Paulo. Haasarr gland
and adjacent adipose tissue froa S
healthy vonen vho died accldentallr
used for controls.
BREaST; H1BBART GLilDS; lEOPtiSRS;
1DIPOSE TISSUE; CUCIIOBtSl
PSSTICIOBS: LIPIDS; CHLOBIBttBO
BTDBOCtRBOBS: CBL08IIE OR01IIC
C08POOI05: BIOtCCOBOUTIOB; BIPBBISL
COaPODIDSt OIBLOBIl; POLTCB10IIIMED
BUBBBTUl DDT; ODE;
BBUCBlOBOCTdOBEZilBt HEPT1CULOB
ZPOHOE
a) Control
b) Ballgnant
c) Breast tissue adjacent to
•alignaocr
Baligaant tissue, adjacent to
apparently norsal glandular and
adipose tissue of nine nosen with
adenocarcinosa of the breast.
obtained fros the a.C. Caaacgo
Bospltal In Sao Paulo. Bassary gland
and adjacent adipose tissue froa S
healthy voaea »ho died accidentally
used for controls.
BtBAST; B1BB&BI OLtlDS; IEOPUSBS;
aDUOSB IISSOB: CUCIBOBIS;
PBSTICIDBSt LIPIDS; CBLORXBatED
BIDSOClBBOBSl CBLOBIBB OBOtllC
COBPOOIOS] BX01CCOBUUTXOB; BIPBSITL
COBMOBDSl DIElDRIBt POIICBIOBIBATBO
BIPBBBILSl ODT; DOB;
BEI1CBLOBOCTCLOHE»IE; BBPMCBLOI
BPOXIDB
8EFBBEICE
Vasseraann, n.
logaelra, D.p.
Toaatis, L.
llicra, k. P.
Shibata, H.
ACie, G.
CUCOS. S.
Vasseraann. 0.
1976
Bulletin of
Environaental
Coataalnatioii and
Toxicology
15(«):«78->8*
lasseraann, n.
Bogueira, O.P.
Toaatis. L.
Blrra, A. P.
Snibata, B.
trie, G.
Cucos. s.
Basseraaaa, D.
1976
Bulletin of
Bafironaental
Contaainatlon and
Toxicology
l5(«)>«78-«8«
-------
DOT, tattl
50-29-3
CU-B9-C15
HI 35*.SO
(to postings is CBENLIIE) .
(COHT1IUID)
TISSOB
9*
•••ucy
gland
95
•Ilk
96
•ilk
97
•ilk
EXPOS DIB SOOTB
AI1LYTXC1L
BBIBOD
cc
OC-BC
6C-BC
IOBBEB
OF CASES
a| S
b| 9
cl 9
•1 5
b| 5
57
29
B1IOB
a) 0.28-1.52 ppa
b) 2.2J-I7.0I pps
c) 0.*0-8.»5 pps
•| lot given
b) lot given
0.02-2.76 PP«
lot given
nut
a) 0.9601 ppa
b) 6.085* ppn
c) 2.3670 ppa
a) 223 gassa/day
b) 167 gassa/day
0.3* ppn
0.0717 ppa
. (KBIT FACE)
GEIBBIL IIFOBBiTZOI
a) Control
b) Malignant
c) Bna*t tissue adjacent to
salignaDcy
(aloes represent the concentrations
in extracted llplds.
Balignant tissue, adjacent to
apparently norsal glandular and
adipose tissue of nine vonen Kith
adeaocarclnoaa of the breast,
obtained Iron the i.e. casargo
Hospital in Sao Paulo. Baasary gland
and adjacent adipose tissue froe 5
healthy noaen *ho died accidentally
used for controls.
BBB1ST; BIRBIBY GLtlDS; IBOPLaSBS;
ADIPOSE TISSOE: CABCIIOBAS;
PESTICIDES; LXPIDS; CBLOBIIATED
BIDBOCABBOIS; CB10BXIB OIG1IIC
COBPODIDS; BIO»CCOBOUTIOI; blPHBIIL
COBPOniDS; OIBLDBIR; POLTC8LOBIIHBD
BIPBEITtS; DDT; DDE;
BEMCBlOBOCTClOBEXlie; ODD;
BIPTtCBlOB EPOIIDB
a) Breast-feeding a others tilth one
child
b) Breast-feeding nothers nith tvlss
Data for 197*.
Tiro groups of breast-feeding not hies,
one group feeding one infant and the
other group feeding twins.
PESTICIDES; CBLOBIIB OBGallC
COBPOOIDSl CBLOBXIaTBD BIDBOMBBOIS;
BBB1ST; IIP1ITS; POODS
Lactatlag •osen in selected areas of
Arkansas and Blssisslppi.
BILK) PESTICIDES: aDIPOSE TISSOB:
BBT4BOLITES; CBLOBIIB OIG1IIC
COBPOOIDSl CBLOIIIiTBD BTDBOCttBOIS;
ttCTATIOl; OXICBIOBD1IE: DDT:
IOI1CBLOI; BEPT1CBLOB BPOXXDE:
DIO.DBII; BEXlCBLOBOCICtOBEXMBt DOB;
1BUIS1S; BISSISSIPPI
Bigher percentages of organochlorine
insecticides and PCB's in ailk of
Bothers 20-29 years than 30-39.
although the forner bad loner levels
in plassa. Ovarueignt nonen had
loner levels than voaan of noraal
might. Besldues concentrated in
extracted lipids of plassa and silk.
Israeli noses 2-* days after aoreal
delivery.
PESTICIDES; BLOOD PLtSBkt BILK;
POPOHTIOI EXPOSOBE; ISBtEL!
CBLOBII1TBD BTDBOCtBBOIS; LIPIDS;
AGE; DDT; DEO; DDE; POLICBLOBIIHBD
BIPBIIILS) BBPTiCHLOB BPOXIDE;
BBUCBLOIOCICLOBZXIIE
BEfEBEICE
•assersann, s.
logueira, D.P.
Tosatls. L.
Birra, I.P.
Shibata, H.
Xrie. G.
Cncos, s.
•asseraann, D.
1976
Bulletin of
Environnental
Contanination and
Toxicology
I5(«):*7B-<8«
Idasovic, T.a.
Sokic, B.
Sslljanski, H-J
1978
Bulletin of
Environnental
Contanination and
Toxicology 20:280-265
Kutx. r.v.
Strasssaa, S.c.
lobs, A.B.
1976
International workshop
on Biological speciaen
collection. April,
1976, Luxesbourg
Polishuk. t.u.
Bon, B.
vassersann, n.
Cacos, S.
lassernaan, D.
Lenesch. C.
1977
Pesticides Bonitoring
Journal 10(«) : 121-129
-------
DM, Total (lo posting* in CRBBLIBB).
50-29-3
CI4-H9-C15
BB 3M.50
(COBTIKUBD)
TISSOE
96
Bilk
99
•ilk
100
Bilk
101
Bilk
EXPOSDBE BOOTE
aBALTTXCAL
BETBOD
GC
TtC
GC
HO BBSS
or CASES
•1 55
b) U2
c) 13
a) SO
b) 15
C) 6
a) 27
b| 9
c) 10
d) IS
e| 10
f) 10
91 «0
a) 48
b) 3D
c) 19
HUGE
a) 0.0-0.298 ag/9
b) Rot given
c) Hot given
a) 5.2-3*9.0 ppb
b) lot given
c) Hot given
a) 0.342-4.97 ppa
b) 1.57-6.68 ppi
c) O.«11-1.77 ppa
4) 0.02S-1.03 ppa
a) 1.14-6.60 ppa
f) 0.600-9.26 ppa
9) 0.062-1.96 ppa
a) 0.1I-11.« ppa
b) 0.33- IS. 8 ppa
c) 0.22-2.58 ppa
tIEAl
a) 0. 114 ug/g
b) 0. 10 1 ug/g
e) 0. 146 ag/g
a) 81.74 ppb
b) 99.0 ppb
e) 55.6 ppb
a) 1.84 ppa
b) 3.06 ppa
c) 1.11 ppa
d) 0.480 ppa
•) 2.55 ppa
f| 3.54 ppa
9) 0.69S ppa
a) 3.48 ppa
b) 3.48 ppa
c) 1.39 ppa
GENERAL mroiniTios
a) Saokers plus nonaaokeca
b) Bonssokfcts
e) Saokers
•oaaa in eaatero Pennsylvania.
predoainatelf alddle class, eean
•dacatioa la. 4 yr
DOT) PESTICIDES: BILKj
SBOK1EG
a) all saspies
b) Colostra*
c) 9-16 Kk after blctk of Infant
Bilk uaplea. hospital* in arban
Oslo. 4 caaples fros Blellagdal, a
valley in southern locvay. >o
occupational exposure.
BXLKi IISZCTICIDES; tlCTlTIOl;
CHLORXIaTED HIDBOCiBBOISj CBLOIIIE
OlOinc COBPOOIDS; PESTICIDES! IOBBW
a) Cotton, corn, and aesaae-grovlng
area
b) Corn and cotton area
c} Corn area
d) Onateaala City
e) Banana area
f) Cottoa area
g) Coffae-groniag area, Bl Salvador
a)-f) in Gnateeala. Highest use of
pesticides on cotton.
Bothers froa lov-incoae faailies in
Gnateaala and Bl Salvador, areas
chosen to represent different degrees
of ase of pesticides.
Overuse of pesticides a particular
problea in tropical countries.
Prevalence of salaatritioa nay
contribute to health effects.
AGilCOtTOBE: CBLOBIBE OBGABIC
COBPOOIDS; CHOP DOSTXBG; DDT:
DmOBIlI Bl SALTADOB: FOOD
COIXlBIBKIOBl GOATBBALA;
BBIACBtOROCIClOHBIAIE! BEPTACBLOB
BPOIIDE: IISECTICIDESi BILB;
lOSBXIXOEAL DEPICIEICIBS: PESTICIDES;
PESTICIDE BESIDOES
a) 1969-70
b) 1971-72
C) 1973-74
Percentages of aetabolite p,p'-ODB
iacraaaed froa 75.0 t 81.6 to 88.5
daring sampling periods 1969-70,
1971-72 and 1973-74 respectively.
p.p'-DDD and p.p'-DDT declined daring
the saae tise periods.
Ontario residents, aean age 24-28 ji.
IIDOSTBZ11 CBE8IC4LS; CaBiDa: *GB!
tOTOPSIESi ADIPOSE TISSOEj BILK;
CBLOUBB OBGtIIC COBPODIDS;
CBIOBOBBBSBIBS; DDT; DIELDBII;
BBUCfflOBOBBKEIE: PESTICIDES!
POLTCHtOBIIaTBD BIPBBIIlSt PESTICIDE
BBSIDDES! POPDLATIOI EIPOSOBE
(BBXT P1GB)
Dradt, P.T.
HerrenKohl, S.c.
1976
Science of the Totil
Bnvironaent
Bakken, t.r.
Selp, 1.
1976
Icta Paediatrlca
Scaadluavica 65:Sl',-539
de Caapos, .1.
Olcxjna-Barxrs, ».E.
1979
trchiws of
Eavironaental
Contaainatlon and
Toxicology 8:43-58
Boldrinet. n.».a.
Braun, B;B.
Frank, B.
Stopps, G.J.
Snout, B.S.
Bc'ade, J.v.
1977
Canadian Journal of
Public Health 68]74-80
-------
DDT, total (lo porting* la CBEBLIIE) .
50-29-3
CU-B9-C15
HI 35*.SO
(COITXIOED)
TISSOE
102
Bilk
103
Bilk, fat
104
Bilk,
•hole
105
Bilk.
•hole
106
Bilk,
•hole
E IPOS DM ROUTE
AULTTXCU
BET HOD
OC-EC
tie
OC/BS
OC-EC
OC
GC
TIC
lonBia
or CASES
154
a) 14
b) 5
o) 18
57
a) U
b) 5
c| 18
25
RMGE
a) 0.01-6.81 agAg Cat
b) lot given
c) lot given
a) lot given
b) lot given
c) lot given
_
0.02-2.76 ppe
a) lot given
b) Bot given
cl lot given
0.0211-0.3039 pps
BEll
a) 1.087 »or- 0.880
•g/kg fat
b| 0.72 «or- 0.«3
ng/kg fat
c) 1. 17 »or- 1.02
eg/kg fat
a) 3.5 ag/kg
b| 2.9 ng/kg
c) 2.8 ag/kg
0.3* pps
a) 0. II ag/k]
b) 0.088 agAg
c) 0.086 ngAg
0. 1272 «or- 0.0198
S.B.
GEEEEIL IIFORIUTIOI
a) 15* Msples. 0.039 »or- 0.031
eg/kg whole nilk
b| Rural seaidente, 19 Maple*
c) ocban cecident*. 51 saaples
3-6 dav« poetpactna. 30X exceedel
Codex lliMntarios Coaalsslon Units.
Level* iacreamd «itb acban re«idenca
and sacking
18-38 yc old*, Canada
alOIXIi CMkOa; iGE; BILK; CBLORXIB
OBGIIIC COBPODIDSi ODE; ODT;
BEIaCBLOROCiaoamiEi LIIDWEI
POUCBLORIIITEO BIPREISLSi POPOL1HOI
EXPOSURE; RDBU tBElS; SBOXXIG; OIBII
1BM5
a) Pooled saaple*, 1967
b) Pooled *aaple*, 1968-1969
C) Pooled samples, 1971-1972
Voaea in Stockholm, Siieden
PBSTICIDBSl POPDLUIOI EZPOSDRBi
BIlRi DDT; DDE; BIOaCCOBOLaTIOl;
SIBDII
100* positive sasplas
Saaples fro* teeldent* of tckansas
and Hississippi
PESTICIDES) IDIPOSB TISSOE; BUR:
ORIIE; BIOaCCOBOLUIOl; BIPBBIIL
COBPOOIOS; CBtOIIIkTEO HTDROCABBOIS;
UUBUS; BISSISSIPPI
a) Pooled saaples. 1967
b) Pooled Maple*. 1968-1969
c) Pooled saaplas, 1971-1972
Vonen in Stockhole, Sweden
PESTICIDES; POPOIMIOI BXPOSDREl
BILK; DDT; DDE; BXOkCCOBOLaTIOl;
SIBDBB
2* he after parturition
19-35 rr old aothers, no history or
•xposar* to pesticide*. India
ODD; DDB; DDT; BBUCHLOROCYCLOBmiB;
LXIDalB; BIOaCCOBOLKIOl; PESTICIDE
RESIDOES; BLOOD: BILK; XIDIa; >DOLTS;
IEIBOBI
SBfCTEICE
Dillon, J.c.
Bartin, G.B.
O'Brien, B.T.
1981
Food and Cosnetics
Toxicology 19:437-4(2
•estoo, G.
197»
labio 3(2):79-83
Kate, I.I.
strasssiQ. s.c.
lobs, I.R.
1977
Pesticide Banageaent
and Xnseoticide
Realatance, icadeaie
Press, Inc., lev Torn,
San Francisco, London,
(pp. 523-539)
lestoo. G.
1974
anbio 3(2) :79-83
SiddifBi. B.K.J.
Saxena, B.C.
Bhargava, a.K.
seth. T.D.
Krishna Burti, C.B.
KUttv. 0.
1981
Environnental Kesearch
24:21-32
-------
Dtgoxln (8 ci)
C«rd-20(22)-enollde, 3-( (0-2.6-did«o«r-b«t«-D-ribo-hBlopyr«no«rl- (1-») -0-2,6-114«oiy-beta-D-rlbo-h«roprrinosyl-( l
(3beta,5beta, 12beta|- (9 CI)
20830-75-5
C«r-H6»-014
HI 780.92. HP about 265 C (decoap)
-« | -2.6-dUeoxy-beta-D-ribo-hexopyranosyl) oxy) -12, 14-dlhydroxy.
TISSUE
107
Hi Ik
108
Bilk
EXPOS DUE BOUTS
9*
- - -
ANALYTICAL
BET HOD
BU
BIA
IDHBER
OP C1SES
1
2
BAICE
Dot given
•) 0.6-0.96 ng/al
b) 0.28-0.61 09/1!
HE1N
1.9 ng/.l
a) 0.78 ng/al
b) 0.41 ng/nl
GEIEBAL HrORHATIOl
Level 7 lay post partnn. Patient
received 0.75 a
-------
Ethane, l,1-aichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)- (8 CI|
Banana, 1-chloro-2-(2.2-dlchloro-1-(«-chloropheayl)athyl)- (9 CX)
CU-BIO-C14
HI 320.05, HP 76-76 C
(CORTIROED)
TX550S
no
Bilk
EXPOSOIB IOOTE
ANALYTICAL
IETBOD
GC
.
RORBER
OF CASES
BARGE
Rot given
REAI
0.0060 ppa
GEREEAL IRFOIBATIOR
Signer percentages ot organochlorine
insecticides and PCB's in silk of
aothera 20-29 years than 30-39,
although the foraer had lover levels
is plasna. Over Height voaen had
lover levels than woaan of noraal
Might. Bealdaas concentrated in
extracted lipids of plasaa and allk.
Israeli vosen 2-4 days after norual
delivery.
PESTICIDES; BLOOD PUSHA; BILK;
POPOLATIOB HPOSDIE; ISBAEL;
CKLOBIIATED RIDBOCABEORS; LIPIDS;
ASEl DDT; ODD; DDE; POLTCBtORIRATED
8IPBERTLS; BEPTACBLOB EPOXIDE;
BEXACBLOBOCICLOREXAIE
BEFEBBRCE
Polishak, Z.«.
Bon, a.
•asseraann, n.
Cucos, S.
lasaaraoan, D.
Lenesch, C.
1977
Pesticides nonltoring
Journal 1 0 (4) : 121-129
Bthane, I, l-dichloro-2,2-bis(p-chlorphanyl)- (SCI)
Benzene. 1.1<-(2,2-dichloroeth/Udene|bis(«-chloro- (9 CI)
72-S«-B
C14-B10-C1*
BR 3SO.«6. BP 221-222 C
tISSOB
111
flaaaarr
gland
112
Bilk
BIPOSOBE BOOTE
HiLITICiL
RETBOD
cc
6C-BC
OC-BC
_
IIOBBBI
OF CISES
a) S
b) 9
a) S
b) 5
lilGE
a) 0.33-0. 86 ppa
b) 0-0. 8» ppa
a) lot given
b) Bot given
(IBxf
H81I
a) 0.5493 ppi
b) 0.2426 ppa
a|
-------
Ethan*, 1,t-dichloro-2,2-bis(p-chlorphenyl)- (8 CI|
Benzene. I, l'-(2,2-dichloroethylidene) bis(4-cbloro- (9 CI)
72-54-8
CM-HIO-C14
HR 350.«6, HP 221-222 C
TISSUE
113
Silk
11*
Bilk
115 .
Bilk
116
•ilk, fat
BXPOSOBE BOOTS
Ingestion
aULTTICIL
BETBOD
OC
OC-EC
GC/BS
oc
GC-BC
•OBBBR
DP CUES
29
5
a) 21
b) 2«
c) 45
d) 45
a) 53
b) 33
BJLIGE
lot gi fen
< 1 ug/kg
a) 0-0.980 ppa
b) 0-0. U9 ppa
c) 0-0.980 ppa
d) lot given
a) lot detectable- 1.45
ppa
b) Not detectable-0.346
ppn
BEX
0.0099 ppi
Dot applicable
a) 0. 100 ppa
b) 0.020 ppa
c) 0.057 ppa
d) 0.001 ppn
a) 0. 151 ppa
b) 0.023 ppa
GEIUAL I* FOR Kill 0»
Higher percentages of organochlorine
insecticides and PCB's In allk of
nothcca 20-29 years than 30-39,
although the tor air had lover levels
In plasaa. Overweight voaen had
lower levels than voaen of noraal
weight. Besidues concentrated in
extracted llpids of plasaa and nllk.
Israeli voaen 2-4 days after noraal
delivery.
PESTICIDES; B10OO PUSH*; BILK;
POPOLaTXOI EXPOSOBB; XSBIBL;
CBLOUI1TEO BtDBOCtBBOVS; LtPIOS;
*GZ; DM: ODD; DOB; POLICB10EH1TED
BXPBBITtS: BEPTtCBLOk BPOZXDE;
BBXkCBLOROCtaOB K» HE
Lactating aothers
17-41 fr olds froa Slavonia Province,
Tagoslavia.
TOGOSUfXa; UCTHTIOI; BXLRi
BX01CCOB01HXOI; BOB1L tBBASj
CBLOBXIaTED BTDBOCtBBOISi CBtOBIiE
OBGAIXC COHPODIDS; CBLOBOBMCBIBS:
DDE; DDT| BEXiCBLOBOCTCLOBESalK:
PESTICIDES
a) Bnral (others, fat basis
b) Orban aothers, fat basis
c) ill Bothers, fat basis
d) all Bothers, Dhole silk basis
Data for SUB of all pesticides and
coapacisona with nines of other
investigators given
Barsing aothers froa Cordoba region.
Spain
SPall; aDOLTS; BILK; CBLOBXIE OBSAIIC
COBPOOIDS; PESTICIDES: IGBICOlTOBBl
IDBaL 1BB1S; OBB1I IBBaS
a) 1966-1970 study
b) 1977-1978 study
1966-70 patients, (University of
alberta Boapltal), 2-10 days
postpartas. 1977-78 pntinets (pnblic
health offices of llberta), 17-309
days postpartas. Besidences, Bdaontoa
or alberta.
BILK: PESTICIDES;
BBXaCBLOROCSCLOBEXilE; ODD; DDE; DDT;
DIEIDBIl; BEPTtCBlOB BPOXXDB;
BBI4CBWBOBBIZBIE: C»«»D»;
POIICBlOBIIaTEO BXPBBinSt
COBPlBITIfB EV1LOUXOBS
BEfEBEVCE
Poliahak, z.u.
Bon, n.
Haasersann, n.
Cncos, S.
Vassersann, D.
Leaeach, C.
1977
Pesticides Monitoring
Joarnal 10(4) : 121-129
Kodrlc-Sait, n.
Salt, I.
Olie, K.
1980
Pesticides Honitoring
Journal 14(1) : 1-2
Poxo Lora, B.
Berrera Rarteache, 1.
Polo vlllar. L.B.
Lopez-Gleeaez, B.
Jodral Vlllarejo, B.
Xglesias Perex, J.
1979
Bevista Espanola de
Pedlatria
35(206):93-IIO
Carrie, B.t.
Kadis. '.I.
Breitkreitx. B.E.
Cannlnghaa, G.B.
Brans. G.B.
1979
Pesticides Bonltoring
Joarnal 13 (2): 52-55
(»EIT P1GE)
-------
Ethane, 1,1-dichloro-2,2-bla(p-chlorphenyl|- (SCI)
Bentena, 1, 1«- (2.2-dichloroethrlldane) bU(4-chloro- (9 CI)
72~5e—fl
C14-B10-CK
HI 350.46, as 221-222 C
(CORTIRDED)
tISSOE
117
Bilk, fat
118
Bilk.
vhole
1
1
EXPOSURE ROUTE
-
ARumcAL
RBTBOD
DC-EC
QC
TLC
BOBBER
OF C1SES
a) 34
b) 6
25
») 0
b| 0
0.00
BARGE
0.0027-0.0370 ppa
HEAB
a) 0.0» ppe
b) 0.002 ppn
0.0129 tor- 0.0018
ppe
S.E.
GEEEm IBrORBATIOR
a) Blgh pesticide usage ace*
b) to* pesticide usage area
Rolen living in StarkTille,
Bississippi (Ion pesticide usage) and
Delta area (nigh pesticide usage).
Saeples in 1973-1975.
BILK: PESTICIDES; DDE; ODD; DDT)
amcBioRoctcLoaEXAEE: BEPTACBLOB
EPOZIDE; OtyCRLORDARE: DIELDRIII:
BISSISSIPPI: COBPABATITE EYALOATIOVS;
BEASOREBEET BETBODS
24 hr after parturition
19-35 yr old eothers, no hlstorr of
exposure to pesticides. India
DDC: DDE; DDT: HEXACBLOROCTCLOBEXAIE;
LIRDAEE; BIOACCOBOLATIOR; PESTICIDE
BESIDOES; BLOOD; BILK: IRDIA; t DOLTS;
BERBOBB
REPKEECE
Barnett, S.f.
D'Ercole. ».J.
Cain. J.3.
Arthur, R.D.
1979
Pesticides flonltorini)
Journal 13(2) :47-5l
Siddlqui, n.r.J.
Saxena, .i.e.
Bharqava, ».K.
Seth, T.D.
Krishna ilurti, C.B.
Kutty, D.
1981
Enrironaantal Beaaarch
24:2«-32
Ethane, 1,1,1-trichloro-2-(o-chloropl>enrl)-2-(p-chlorophenrl)- (SCI)
Benzene, l-chloro-2-(2,2,2-trichloro-l-(4-chlorophenrD ethyll - (9 CI)
789-02-6
CU-H9-C15
B* 354.49. BP 74-74.5 C (cor)
TISSOE
119
Raaearr
gland
EIPOSDBE SOOTE
imiTXCaL
BETBOD
CC
GC-BC
BVBBBR
or CASES
a) 5
b) 9
c) 9
BAtfGE
a) 0.21-1. 17 PP«
b) 0-12.19 Pp"
c) 0-2.28 ppa
(BEIT
HEAR
I) 0.7775 ppn
b) 2.8487 ppa
c) 1.0044 ppn
P»GB)
GZREBAL IirORNATIOR
a) control
b) Balignant
c) Bceast tissue adjacent to
uli<]n> DC 7
Balignant tissue, adjacent to
apparent IT noreal glandular and
adipose tissue of nine vonen vith
adenocarcinoea of the breast.
obtained fros the A.C. Caeargo
Hospital in Sao Paulo. Bassary gland
and adjacent adipose tiaane fees 5
healthy *oeen *ho died accidentally
used for controls.
BBEAST; BABBART GLARDS; REOPLASBS;
ADIPOSE TISSDE; CARCIROBAS)
PESTICIDES; L1PIOS; CBLORIBATED
HIDROCABBOIS; CBlORIlB OBflARIC
COBPOOIDS; BlOACCOaOLAIIOII BIPBBRIL
COBPOORDS; DIELORIR: POLTCBLORIRATED
BIPRERTLS; DM; DDE;
HEXACHLOBOCICIOBHARE; ODD;
BBPTACHLOE EPOXIDE
iEFBRERCE
lassereann. B.
Rogaelra, D.P.
Toaatii, L.
Birra, A. P.
Shibata, B.
Arie, c.
Cucos, s.
lasseraann, D.
1976
Bulletin of
Enviroaeental
Contaaiaatlon and
Toxicology
1S(»):478-484
-------
Ethane, 1,1, l-trichloro-2-(o-chlorophenyl|-2-(p-chlorophenyl)- (8 CI)
Benzene. 1-chloro-2-(2,2,2-trichl3ro-1- (4-chlorophenyl) ethyl}- (9 CI)
789-02-6
CU-B9-C15
BB 35*.49. BP T*-7«.S C (cor)
(COBTIBOED)
TISSUE
120
Bilk
121
Bilk
122
Bilk
123
Bilk
EXPOSOBB BOOTE
IBaLTTICaL
BBTHOD
OC-EC
OC
GC
TLC
GC/BS
BOHB8B
OF C1SBS
a) 5
b) 5
29
»9
a) 10
b) 25
c) 35
11 10
•) 20
C| Bat
given
BMGE
a) lot given
b) Bot given
Bat given
1.6-120.9 ppb
a) Bot given
b) Bot given
c) Bot given
d) Bot given
e) Bot given
f) 1-aa ng/g
BEtB
a) 2.8 gaaaa/day
b) 3. 3 gaaaa/day
0.0073 ppn
18.53 ppb
a) 3 ag/g
b) I ng/g
e) 6 ng/g
a) Bat detectable
e) 1 ng/g
tt 3 ng/g
GEBEBaL IHPOKflATIOM
a) Breast-feeding aethers with one
child
b) Breast-feeding eotbers tilth tulns
Data for 197«
TDC groups of breast-feeding Bothers,
one groap feeding one infant and the
other group feeding tuins.
PESTICIDES; CBLOBIBE OBG1BXC
COBPOOBDS; CBLOBIMTZD HTDBOCtBBOBS;
BBEaST: IBFaBTS; FOODS
Higher percentages of organochlorlne
insecticides and PCB's in silk of
a others 20-29 rears than 30-39,
although the foraer had lover levels
in plasu. Overveight vosen had
loner levels than voaen of normal
•eight. Besidnes concentrated in
extracted lipids of plasaa and eilk.
Israeli vosen 2-* days after aorsal
delivery.
PESTICIDES; BLOOD PLISBM BILK;
POPOLMIOB EZPOSOBB: ISB1EL;
CBLOBIB1TED BTDBOCiBBOBSt LIPIDS;
aGEj DDT; ODD; DDE; POLTCBLOBIBatED
BIPHBBTLS; BEPTaCBLOB EPOZIDE;
BBUCBLOBOCTCLOBEIaBE
Bilk sasples, hospitals in urban
Oslo. * sasples froa Balliagdal. a
valley in southern Borvay. Bo
occupational exposure.
BILK; IBSECTICIDES; UCTaTIOB;
CHLOBIBiTED BIDBOC1 BBOBS ; CBLOBIBE
OBGaBIC COBPOHBDS; PESTICIDES; BOBBaT
a) Eastern Canada
b) Quebec
c) Ontario
d) Central Canada
e) Bestern Canada
f) latiooal average, sasples above 1
ng/g
Bational Survey. 1975
BIPBEBTL COBPOOBDS; CiBaDa; CBLOBIBE
OBGaBIC COBPOOBDS; DDE; DDT;
DXELDBIE: BBPTiCBLOB EPOXIDB;
BEXtCBLOBOBEBZEBE:
BBXACBLOBOCXCLOBEX1BE; BILK;
BOEaCBLOB; OIICBLOBD»IE! PESTICIDES;
POIICBLOBIBMCD BIPBEBTLS;
POLTCBLOBXBaTED TEBPHBBILS
CrE9E¥CE
Adaaovic. T.n.
Soklc, B.
Selljanskl, i-j
1978
Bulletin of
Envltonatntal
Contasiaation and
Toxicology 20:280-28%
Polishuk, Z-W.
Bon, It.
Basseraann, H.
Cncos, S.
vasseraann, 0.
Leaesch, C.
1977
Pesticides Bonitoriug
Journal 10 («) : 121-129
Bakkea, 1. P.
selp. N.
1976
icta Paediatrlca
Scandiaavica 65:535-539
Bes, J.
Davles, D.J.
1979
Bulletin of
Environaental
Contaslnation and
Toxicology 21:381-387
(•EXT PAGE)
-------
Ethane, 1.1,1-trichloro-2-(o-chlorophenyl)-2-(p-chlocophenyl)- (8 CI)
Benxena, l-chloro-2-(2,2,2-trichloro-l- (4-chlorophenylt ethyl)- (9 CI)
789—02—6
C14-B9-C15
BB 354.49, BP 74-74.5 C (cor)
(COBTIEOBD)
TISSUE
I2«
•ilk. fat
125
Bilk, fat
.,,
EXPOSURE iODIE
IIUTTIC1L
HETBOD
GC-EC
6C-BC
EDBBEB
OP CASES
•1 53
b) 33
«) 31
b) 6
BUGE
a) irot detactabla-0.072
ppi
b) lot detect»ble-0. 169
PP«
a) 0-1. OB ppa
b) 0.02-0. I* ppa
BE
a) 0.003 p
b) 0.031 p
a) 0.21 pp
b) 0.050 p
GEBEB1L IRPORBtTIOl
a) 1966-1970 stair
b) 1977-1976 study
1966-70 patients (Oniraralty of
llbarta Bospital). 2-10 days
postpartaa. I977-7B patieats (public
health offices of llberta), 17-309
day* poatpartua. Residences. Edaonton
or ilberta.
BILK; PESTICIDES;
BEXlCBLOROCycLOBEXiBE; ODD; DOB; DDT;
DIELOBIB; BEPTftCBLOR EPOXIDE;
BEXaCBLOBOBEnBEE; C»«iD»:
POIICBlOBIKiTED BIPBBRILS;
COBPaBATXTE ETiLOMIOIS
a) High p«>ticlde usaga area
b) Lo« paatlcid* uaag* ac«a
Boaan liTing la Stackvllla.
Hiaaiaaippi (low peaticld* aaagc) and
Delta area (high paatlclda uaagaj.
Saaplaa in 1973-1975.
BILK; PESTICIDES; DDE: ODD; DDT:
BEXaCBLOBOCICLOBmEE; BEPT1CBLOB
BPOXIOB; OXTCBLOBD&BBt OIELDBIB;
BISSISSIPPI; COBPMaTItB EfUaaTIOBS;
BE1SOBBBEBT BETBODS
BEPEBEBCE
Carrie, B.«.
Kadis, r.i.
Bcaitkraitz, H.E.
Cuaninghaa, G.B.
Ecaas, C.B.
1979
Pasticldas lonltorlng
Journal 13(2) : 52-51
Barnatt, B.u.
O'Ercole, ».J.
Cain, J.D.
arthnr, R.O.
1979
Pcsticldas Bonitorlag
Journal 13(2) : a 7-51
Ethana, I, I, t-trlchloro-2,2-bla(p-cbloropbanfl) - (SCI)
Bauana, I, I1-(2,2,2-tcickloro«thrlUana| bla(«-c»loro- (9 CI)
50-29-3
CU-B9-C15
BB 354.50. BP 108.5-109 C. BP 260 C, TP 1.5X10(8-7) aa Bg at 20 C
TISSOE
126
Baaaarr
gland
EXPOSURE BOOTH
ilALTTICIL
HBTHOD
CC
CC-BC
BOBBER
OP CiSES
a) 5
b) 9
Cl 9
BUGE
a) 1.58-8. 2» ppa
b) 1.35-6.40 ppa
c) 0.39-2.81 ppa
(IEII
HEtR
a) 3.5516 ppi
b) 4.3978 ppa
c) 1.4266 ppa
PIGE)
aBBBBtL IBPORBHIOB
a) Control
b) flalignaat
c) Braaat tisaua adjacaat to
aallgnancT
Tha Talnaa raptaaant tha
coDcaatcatlona la axtractad llpida.
Baligaaat tiaaae, adjacent to
appacantly noraal glandular and
adlposa tissaa of nioa noaan with
adeaocarcinoaa of tha braast.
obtalnad froa tba I.e. Caaargo
Bospltal in Sao Paulo. Baaaarj gland
and adjaeant adipoa* tiaana froa 5
haalthy voaan *ho diad accidentallT
aaad for controls.
BBE1ST; HiBBIBI 6L1BDS; BBOPL1SBS;
tOIPOSB TISSOB; CkRCIBOBtS:
PESTICIDES; LIPIDS; CBLOBIEaTBD
BTDBOCtBBOBS; CBLOBIBB OBOaBIC
COBPOOBOS; BIOtCCOBOUTIOB; BIPBBBTL
COBPOOBDS; DIE1DBIB; POLICBLORIBtTED
BIPBBBIIS; DDT> DDE;
BBHCBLOBOCTCLOankBE: BBPTkCBLOB
BPOXIDE; ODD
REPEBBICE
Vaasaraaan, B.
Eognaira, D.P.
Toaatls. L.
Birra, 1. P.
Sbibata, B.
aria, G.
Cucos, S.
Bassaraann. 0.
1976
Bulletin ot
Eavironaaatal
CoataainatlOD and
Toxicology
15 (U) :478-«8l
-------
Ethan*, 1,1, l-trichloro-2,2-bis(p-chlorophenYl) - (B CI)
Benzene, I, I1-(2,2, 2-trichloroethylidene) bis(»-chloro- (9 CI)
50-29-3
CU-H9-C15
HI 35«.50, HP 108.5-109 C, BF 260 C. TP 1.5XIO(E-7) mm Hq at 20 C
(CONTIBUED)
TISSOE
127
Bilk
128
Bilk
129
Bilk
130
Bilk
131
•ilk
EXPOSOKE BOOTI
'
AIALTTICU
HETBOD
CC
OC/BS
CC
GC-EC
TIC
GC
..
GC
GC-EC
BOHBBB
or CISES
a) 6
b) 9
6
at 1*
b| 59
c) 15
d) 97
2
a) 5
b) 5
BINGE
a) 0.006-0.030 ppi
b) 0.002-0.011 pp«
a) Bot detectable-2.«5
Ppa
b) Bot detectabl«-0.20
ppa
28-61 agAg
10-35 agAg
9-19 agAg
6.6-19 agAg
0.2*-0.71 ag
a) Bot given
b) Bot given
a) 0.013 ppa
b) 0.006 ppa
O.tl ppa
0.03 ppa
*0 agAg
18 agAg
13.5 og/kj
10 agAg
0.*8 ag
a) 01 gaaaa/lay
b) 3« gaaaa/iay
GEBEBAL XBFOBHiTXOK
a) Ben Brunsvick mean
b) Bova Scotia voaen
Six lactating Bothers froa Sen
Broasvlck and 9 froa Bova Scotia.
BILK; BEE 1ST; CAKADA; PESTICIDES;
CBLOBIRATED BIOBOCABBOBS: CHLOfilBE
OBOABIC CORPOOBDS: BIOACCUROLATIOB;
LACTATIOR; POLTCBLOBIEATED BIPHEHIIS;
DDT; ODE
a) values for ailk fat
b) Values lot vhole ailk
Saaplas froa residents ot Ravaii
collected froa 1964-1973
PESTICIDES: 81»»II: KIDS; fETAL
RERBBAEBS; BILK; OTEHOS; BLOOD SEBOK;
DDT; DDE; DIELDBIB
a) Apr-Jaly 1967
b) Bov 1971-pec 1972
c) Jaae-Bov 197*
d) Bar 1976-Bar 1977
Each cane represents a pooled eaaple
froa 10-20 Bothers.
Saaplas fros voaen in Stockholi,
Svedea
PESTICIDES; SBEDEB; BILK; BIPBEBIL
COBPOOBDS; CBLOBIBE OBGAEIC
COBPOOBDS: CBLOBOBBBZEIES;
POLYCBLOBIBAIBD BIPHEBTLS; DIELDBIB;
DDT; DDE; BEXACRLOBOCICLOBEXAIE
Aiaants varied for different
feedings. Talnes are daily total.
Sanples froa donors at various tiaes
of breast feeding and at different
tiaas of the day.
SILK; PESTICIDES; PESTICIDE BESIDOESi
rOirCBZOBIEATED BIPBEBTLS;
BIOACCOHOLATIOE; BEXACBLOBOBEBZBBB;
DDT; BBUCBLOBOCTCLOBEXaBE;
BEPI1CBLOB BPOXIDE; OXYCBLOBDAEE;
EOBACBLOB; DDE; DIELDBIB
a) Breast-feeding aothers "ith one
child
b) Breast-feeding aethers vita tvins
Data tor 197«
Tvo groups of breast-feeding aothers,
one group feeding one infant and the
ether group feeding tvins.
PESTICIDES; CHLOBIBB OBGABIC
CORPOOBDS; CBLOBIBATEO BTDBOCABBOIS;
BBBAST; IBPABTS; POODS
BEfEBEBCE
Rasial, C.J.
Rntzlnger, n.
zitko. v.
Crocker, 3.
197*
Bulletin of
Environmental
Contaalaation and
Toxicology
12(31:258-267
Klaaaar, H.w.
Budy. ».B.
Takahashi, H.
Haley, I.J.
1977
Clinical Toxicology
Bestoo, G.
loran, n.
1978
Anbio 7(2):62-64
Res, J.
Oavlea, o.J.
1978
Cheaosphere
7(91:699-706
Adaaovic, T.H.
Sokic, B.
Sailjanski, H-J
1978
Bulletin of
Bnvironaental
Contaainatioa and
Toxicology 20:280-285
(IEIT PAGE)
-------
Ethan*, I. 1, l-trichloro-2.2-t>i«(p-chioroph«nrl) - (8 CI)
Beazana, I, |i-(2.2,2-trichloroethrlldene)bis(*-chloro- (9 CI)
CU-H9-O.5
I* 354.50, RP 108.5-109 C, BP 260 C, TP 1.5X10(1-7) a> 89 at 20 C
(coiriioiD)
TISSOE
132
Bilk
133
•ilk
13*
Bilk
135
•Ilk
136
Bilk
ETPOSOBE BOOTS
AIALTTICAL
METHOD
CC
GC
TLC
DC
OC
IOBBBI
OF CASES
57
29
50
,
•
•
2 of 51
a) 23
b) 20
c) 12
d) *0
e) 38
t\ 19
9) 20
b) 19
BAIGE
0.01-0.8* ppa
lot given
2.3-138.3 ppb
lot given
a) lot glren
b) lot given
c) lot given
d) lot given
a) lot given
f) lot given
g) lot given
h) lot given
- • • (izn
BB1I
0.09 ppa
0.0122 ppa
17.89 ppb
0.008 ppa
a) 1.3 ppa, 1
b) 1.« ppa, 1
c) 1.3 ppa, 1
d) 0.9 ppa, 1
•) 0.9 ppa, 1
f) 0.8 ppa, 1
9) 0.9 ppa,
h| 1.0 ppa,
<
PAGE)
fat basis
fat basis
fat basis
fat baals
tat basis
fat bails
tat basis
fat basis
OEIBBlt IirOIBATIOl
Lactatlng voeea In (elected areas of
Arkansas and Blssissippi.
BILK; PESTICIDES; ADIPOSE TISSOE;
BBTABOLITES; CBLORIBE OBGAIIC
COBMOIOS: CBLOIIIATED BIDROCARBOIS;
1ACTATIOI; OITCBLOBDAIE; DDT;
IOIACBLOB; BEPTACBLOI BPOIZOB;
DinORIl; aESACBLOBOCtClOBIXAlE; ODE;
ARKAISAS; RIS5ISSIPPI
Biqhar percentages of organochlorina
insecticides and PCB's ID allk of
•others 20-29 rears taan 30-39,
although the foreer had lover levels
la plasaa. Overvelght voaen had
loner levels than voaea of naraal
velght. lesldues in extracted llplds
of plasaa and ellk.
Israeli voaen 2-a dava after noraal
delivery.
PESTICIDES: BLOOD PLASRA; HILKj
POPOIMIOI BXPOSDBB; ISRAEL;
CBLORIIATED BIDROCABBOIS; LIPIDS;
A6B; DDT; ODD; DDE; POLtCBLOIXIaTBD
BIPBBITtS; BBPTACBZOR BPOXXOB;
BIXACBLOROCICLOIUAIE
Bilk saaplea, hospital* in urban
Oslo, a saaples fro* Bailingdal, a
valley la the central pact of
southern Borvav. Bo occapational
exposure.
BILKi IISECTICIDBS; IACTATIOI;
CBLOBIIATED BTDROCABBOIS; CBLOUII
OBGAIIC COBPOOIDSi PESTICIDES; 101IAT
Randoa subjects of greater St. Louis.
BO, eetropolitan area.
PESTICIDES: CHLOBIIE OBSAIIC
COHPOUIDS; DDT; DDE; DIBLDRII;
BBXtCBLOIOCTCLOBEXABB; BBPTACBLOI
EPOXIOBl BILIt HISSOOBI; CORPAIATITE
EVALOATIOIS
1970
1971
1972
1973
197«
1975
1976
1977
Batisated froa graph
Rothara in Osaka Prefectare
BIPBBBIL COBPOOIDS; CHLORIIB OROAIIC
COHPOOIDS; DDE! DDT; DIBLDRII;
BBXaCRLOBOCICLOBEXalB; JAPAI; BILK;
POIICBLOBIIMBD BIPBBITLS
BSPBEEBCE
Ktttx, F.H.
Straaaaao, S.C.
tobs, A.R.
1976
International VorkJhop
on Biological Speclaea
Collection, April,
1976, Luxeabaarg
Polishak. Z.v.
Boa, a.
Baseeraann, R.
Cacos, s.
Hasseraann, D.
Lenesch, C.
1977
Pesticides Ronltoring
Journal 10(«) : 121-129
Bakkea, A.r.
selp. R.
1976
Acta Paediatrica
scandlnavlca 65:535-539
joauoa, T.
Liu, G.J.I.
Arabrastac, J.
Kettelhat, L.I.
Drucker, a.
1977
Aaerlcan Joacnal of
Clinical lateIt Ion
30:1106-1109
lakashljl, T.
latanaba, I.
Kawabara, x.
loahida, s.
Boil, s.
paknshiaa, S.
Kashlaoto. T.
Rovaaa, It.
innita. I.
1979
Archives of
Bnvlconaaatal
contaaiaatioa and
Toxicology 8159-66
-------
Bthane, 1.1. l-trlchloro-2,2-bla(p-chlorophenyl)- (8 CI)
Beazeu, 1.11- (2,2, 2-trlchloroethylidene)bls(4-chloro- (9 CI)
50-29-3
C1I-B9-C1S
(K 354.50. HP 108.5-109 C, BP 260 C. VP 1.5X10(E-7) an Hq at 20 C
(COITIIOBD)
TISSUE
137
111 lit
138
Milk
139
Bilk
.
1*0
Bilk
141
Bilk
i
EIPOrOBE BOOTS
lagestioa
AlALTTICAt
HETBOD
OC/BS
*
GC-BC
6C/BS
— -
GC-EC
GC
I
IOHBEB
or CASES
a) 10
b| 25
oj 35
d) 10
a) 20
f) lot
given
10
25
a) 14
b) 11
c| 10
d) 9
a) 21
b) 24
c) 45
d) 45
BAIGE
a) lot given
b) lot given
c) lot given
d) lot given
e) lot given
f) 1-21 ng/g
8.0-135.4 og/kg
Bot given
a) lot given
b) lot given
c) lot given
d) lot given
a) 0.095-33.122 ppa
b) 0-10.361 ppa
c) 0-33.122 ppa
d) lot given
MAI
a) 5 nj/g
b) 7 ng/g
c) 6 ng/g
d) 5 ng/g
e) 8 ng/g
f) 6 ng/g
•>
50.8 ag/kg
180 » at - UO ppb
a) 50 » or - 38 ngAg
b) 49 * or - 31 ug/kj
c) 39 » or - 17 ag/kg
d) 29 » or - 13 agA]
a) a. 223 ppa
b) 2.795 ppa
e) 3.461 ppa
d) 0.065 ppa
GLHE6AI MrOBIUTIOl
a) Eaatern Canada
b) Quebec
c) Ontario
d) Central Canada
e) Vestern Canada
f) latlonal average, saaplea above 1
ng/g
latioaal Survey, 1975
BIPBEIT1 COBPODBDS; CHAD*; CHLORIIE
ORGAHC COBPOOIDS; DOE; DDT;
OIELOBII; HEPTkCBLOa EPOIIDB;
BBXtCBLOKOBEIZEBE;
BEUCBLOEOCICLOHEX1IE; SILK;
IOI1CHLOB; onCBLOIOMB; PESTICIDES;
SOITCBLORIIJITID BIPBEITLS;
POLXCBlOBIiaTED TBBPBEIILS
Lac tat ing aothers
17-41 vr olds froa Slavonia Province,
Yugoslavia.
TOGOSL1TI1; UCTMIOl: BILRl
BIOaCCOBOlaTIOl ; BOBaL IBBaS;
CBtOBIBHED BIOIOCABBOIS; CBIOBZIE
OBGABIC COBPOOBDS; CRtOBOBEICBIESt
DOB; 001; HEJUCBUJBOCTCIOHNMB;
PESTICIDES
Bilk bank donor*
California
CillrOBBIk; IDOITS; SILK!
BIOtCCOBOLlTIOB; LtCUTIOl; DDE] DDT;
PESTICIDES
a) Oslo, large industrialized city
b) Bergen, large indoatrialixed city
c) Barstad, ssaller city vith large
cheaical/petcocheaical coaplax
d) Porsgronn, non-industrialized
fishing coHunitv
1976 survey. Significant decrease at
all aaapling locations compared to a
1969/70 snrvev.
lonegiaa (others, ages 25-28 yr.
ADIPOSE TISSOE; BILK; COBPABATITB
BTAtOATIOIS; NOBIAT; AD01TS;
AUTOPSIES ; IBIBOBI; DDT; CBIORIBATBD
BTDBOCABBOIS; DDT; PESTICIDES;
P01TCBLOBIIATEO BIPBEITLS
a) Rural aothers, fat basis
b) Urban aethers, fat basis
e) All sothers. fat basis
d) All Bothers, vhole silk basis
Data for SUB of all pesticides and
coaparlsons ulth values of other
investigators given
lursiag aethers fcoa Cordoba regioa,
Spain
SPAU> ADDLTS; BXUE: CBLOBKB OR6AIIC
coavoonost PESTICIDKSI *eaxcnTO»>
REFMSSCf:
lies, J.
Daviea, D.J.
1979
Bulletin of
Envlronaental
contaalnatloa and
Toxicology 21:381-387
Kodrlc-Salt, it.
Sait. I.
Olio, K.
1980
Pesticide* Honitoriag
Journal lk(l| : 1-2
Barrod, J.R.
Asgulth, B.T.
1980
leu England Journal of
Bedicine
303(16) :945-946
Brevik, E.I.
Bjerk. J.E.
1978
Acta Pharaacologica et
Tosicologica
43(l|>59-63
Pozo Lora, I.
Berrera Barteache, A.
Polo Tillar, I. a.
lopez-eiaenei, B.
Jodral Tillarejo, B.
Iglesias Perez, J.
1979
Revista Espanola d«
Pedlatria
35(206)193-110
^
-------
Ethane, 1,1,1-trichloro-2,2-bls(p-chlorophenyl)- (6 CZ)
Benzana, I. l'-(2,2,2-trichloroethylldeno)bi8(«-chloro- (9 CI)
50-29-3
CI*-B9-C15
at 35*.SO. HP 108.5-109 C. BP 260 C, TP 1.5X10(8-7) ni Hg at 20 C
(CONTIROED)
TISSUE
U2
Bilk
1*3
Hllk
•
U*
Ulk, fat
1*5
HiUt. fat
EIPOSOBB ROOTB
1ULTTIC1L
HBTHOO
CC-8C
h
CC
ec
10 HUB
OF CUBS
154
50
a) 1«
b) 5
c) 18
81HGB
a) 0-2.51 ig/kg fat
b) lot given
c) lot given
32-520 ppb
t
lot given
a) lot given
b) lot given
c} lot given
" ' (MBIT
Bill
a) 0.204 »oc- 0.262
•9/kg Cat
b) 0. l« »or- 0.11
•g/kg fat
el 0. 18 «or- 0.12
•g/kg Cat
160 ppb
2287 ig/kg
*
a) 1.3 eg/kg
b) 1.0 ig/kq
c) 0.63 ig/k]
PAGE)
GEHEBil IIFOBBATIOB
a) 15* «»«pl«s, 0.007 »or- 0.009
•g/kg whole allk
b) Bual, residents 19 aaepleii
c) Drban, residents SI aaeples
3-6 lays pastpactoa
18-38 jt olds, Canada
ILDBIli CtltOt; AGE; BILK; CHLOBIIE
OI61IXC COBPODIDS; DDE; DOT;
BEIICUOBOCTCIOHBUX; IZIOtlE;
P01TCBLOBIIITEO B1PBBITLS; POPOLUIOI
EIPOSOBB; BBB11 »BE«S; SBOKIKi DBBtl
1BB*S
extracted llplds. Jan 1979 to Feb
1980, 3-»6 days postpartna. lo
significant correlation vlth
residence, age. Height, naaber of
children previously nursed, household
ase of non-persistsnt pesticides, or
occupation of spouse . Higher, but
nonsignificant levels in WO»D with
higher frequency of neat conniption,
and in those in hones vith pest
control treatment.
Bealthy 18-37 yr old lavaiians
lODlTSl »GBJ BAWilll MILK;
CBLO1II1TED BTDBOC1BBOIS; DOE; ODt)
DIELDBIli BEUCBLOROCICLOBBXUE;
HBPI»CBIOB BPOiroB;
BEI1CKLOBOBEIXEIB; LIID1IB;
•OlaCBlOBt OXICHLOBD1IB! PESTICIDES;
POITCBLOBII4TEO BIPBEITLS; DIETS;
UCT1TIO*; PESTICIDE RESIDUES;
POPOL1TIOI BXCOSOIB
85 sasples-each is average froa 20
•others. Bilk obtained fro* lactaria
in Slovakia, 1971-1973. Values
estiuted fron graph.
PESTICIDES; BILK; FITS;
CZBCBOSLOTIKIi:
BBX*CHtOBOCIC10BSX*IB: DDT; DDE;
BBXiCBlOBOBEIZIIE
a) Pooled sasples, 1967
b) Pooled sanples, 1968-1969
c) Pooled saiples, 1971-1972
Honan in Stockholi, Sveden
PESTICIDES; POPOL1TIOI BIPOSOBE;
BIUC; OOTj ODB; BIOiCCODOLlTIOl;
SIBDBI
BEFEBEICF.
Dillon. J.C.
Martin. G.B.
O'Brien, H.T.
1981
Food and cosnetics
toxicology l9:«37-*«2
Takahashl. 1.
Saldia. 0.
takel. G.
Bong, L.
1981
Ball* tin of
Environmental
Contaalnation and
Toxicology 27:506-511
sxokolay, 1.
Bocival, L.
Ohnak. J.
Badaric, i.
1977
Ecotoxicology and
Bnvironaental Safety
1:3*9-359
Bestoo, G.
197*
inbio 3 (2): 79-83
-------
Ethan*. 1,l,1-trichloro-2,2-bls(p-chlorophenyl|- (6 CI)
Benzene, I, l»-(2.2,2-trichloroethyltdenn)bis(«-chloro- (9 CI)
50-29-3
CM-B9-C15
HI 15*.SO. HP 108.5-109 C, BP 260 C. YP 1.5X10(8-7) •• Sg at 20 C
TISSUE
U6
Hilk. fat
1*7
Bilk, fat
U8
Hilk, eat
U9
Bilk.
*" * m 9
•hole
BIPOSOBB IODTB
»
alaLYTICIL
RETBOD
6C-2C
8C-BC
6C-EC
CC-BC
""lOBBEB™
OF CUES
at 53
b) 33
a| 3*
b) 6
290
HUGE
a) tot detectable- 1 1.25
ft*
b) Tcace-6.35 ppa
a) 0.3«-18.*S pp»
b) 0.26-0.53 ppn
a) lot given
b) lot given
c) lot given
d) lot given
•) Bat given
f) lot given
0.003-5.686 ppn
BB»i"
a) I.I* ppn
b) 0.*37 ppn
a) 1.25 ppa
b) 0.390 ppn
a) 0.*S * or - 0.22
PPn
b) 0.*2 » at - 0.*6
PPn
c) 0.38 » or - 0.16
PPn
4) 0.** » or - 0.15
PPn
•) 0.«9 » or - 0. IS
ppn
H 0.29 » or - 0.09
PPn
0.378 ppn
CEIEBU IIFORRlTIO*
a) 1966-1970 study
b) 1977-1978 study
1966-70 patients (Onlverslty of
alberta Bospltal), 2-10 darn
pMtpattan. 1977-78 patients (public
health offices of lib. eta), 17-309
days postpactun. Residences. Ednontoo
or alberta.
BILK; PESTICIDES;
BBUCRLOiocictoantBB: ODD; DOE; DDT;
01 EID BID BEPMCHtOB BPOXIPB;
BEX1CBLOROBEIZEIE; CallOa;
POUCUOEIBaTED BIPBBBILSi
COBPUHIfE ETIL01TIOIS
a) Blgh pesticide usage area
bj Lou pesticide osage acea
tones living In Starkville,
Blssissippi (Ion pesticide asage) and
Delta acea (kigk pesticide nsage).
Saaples In 1973-1975.
ant; PESTICIDES; DDE: ODD; DDT;
BEZlCBLOIOCTCtOBEUIE; BEPT1CBLOI
EPOSIDE; OXICBLOID1IE; OIELOUI;
USSISSIFH; COBPM1TITB EfliaaTIOBS;
BEaSOBEBBBt BBtBOOS
a) 1972, «0 staples
b) 1973. 38 saaples
e) 197*. 19 sanples
d) 1975. 20 sanples
e) 1976. 19 sanples
f) 1977, 20 sanples
100-UI lactating vonen. 2 nontfes
after delivery. Residents of Osakn
Prefecture, Japan, varied diets and
ecviroane ntal conditions.
PESTICIDES; DDT; OR6MIC CBLOIIIE
COITOOIDS; JiPM; 1 DOLTS; UCtaTIOB:
BUK: BI01CCDBD11TIOI:
POITCRLOIIIITED BIP BOILS
all 290 eanples skoeed neasarable
gnaatltles of p.p'-ODT and p.p'DOE.
sone skoned o.p'-DOt and p>p*-DDD.
p.p'-DOB and p.p'-DDD anoants >ere
adlnsted to their a gain lent ppa DDT
in naking np the total. Differences
in levels in coananities associated
•1th nse of DDT by latloaal Balarla
Eradication Service. Conparlson done
of levels in nother's allk fron 3
connnnltles in 1970 nnd 197*.
Bilk sanples collected fros 290
lactating noaen by naaaal expression
uadar snpervislon. Eight eonnuities
studied.
BZLK; 6D4TEBALI; IISBCTICIDBS;
L1CT1TIOI) CBLOIIUTED BTDBOCilBOBS:
PESTICIDES
blltfdtCt
Cnrrie, S.I.
Kadis, V.I.
Brcltkr«itz, I.E.
Canniaghan, n.t.
Brans, G.a.
1979
Pesticides Monitoring
Journal 13(2) : 52-55
Baraett. B.I.
D'Ercole, l.J.
Cain, J.D.
Arthur, R.D.
1979
Pesticides Honitoring
Journal 13(2) :«7-Sl
Taknshi}!, T.
latanabe, I.
Knuabara, I.
Toshida. S.
(oyana. I.
Konita. I.
1979
International Archives
of Occupational and
Bnvironnental Bealth
«3>I-I5
linter. B.
Thonas, B.
leraick, S.
Levin, S.
Par vac, a.T.
1976
Bulletin of
Eavironnentnl
Contasiantion aad
Toxicology
16 (6): 652-657
(IBXT PICE)
-------
•than*, 1,1, l-trlchloro-2,2-bis(p-cklorophenyl)- (a CI1
Bantene, 1,l'-(2,2,2-trichloroethylldene)bls(«-chloro- (9 CI|
50-29-3
CU-B9-C1S
81 35*.SO, BP 108.5-109 C, Bt 260 C. fP 1.5110(8-7) •• Bg it 20 C
(COITIIOBO)
TISSOE
ISO
Bilk,
•hole
151
Bilk,
•hoi.
152
Bilk,
•hoi*
153
Bilk,
vkole
15*
Bilk.
•hoi*
155
Bilk,
•kole
BXPOSOBI MOTE
AIALITXCAL
1ETBOD
OC-EC
MS. '
OC/BS
GC-EC
6C-EC
OC-EC
GC
OC
nc
IOBBBB
or CASES
57
57
•I 39
b) 92
C) 3*
22
•t 1*
b) 5
C) IB
25
BAIGE
0.01-0.8* ppi
0.01-0.9* ppi
a) 0.029-0.3*5 ppi
b) 0.00*-0.158 ppi
c) 0.012-0.273 ppi
0.002-0.025 PPI
a) lot giT«n
b) lot given
c) «ot glfen
0.0072-0.113* ppi
SEA*
0.092 ppi
0.09 ppi
•) 0.119 ppi
b) 0.033 ppi
c) 0.073 ppi
0.010 ppi
•| 0.0*0 igAg
b) 0.030 ig/kg
c) 0.020 ig/kg
0.0*91 »oc- 9.0091
ppi
S.B.
GENERAL IIFORBATXOI
Saaplas Ixom 17 legroes aid *0
Caucasians in hospitals in Arkansas
and Bississippi.
PESTICIDES; PESTICIDE BESIDOES: SILK;
POPOLATIOI EXCOSORE; RABBABI GLAIDS;
LACTATION BiOACcanaiATioi:
BISSISSIPPI; ARKAISASt PLtCEITA
1001 poaltlie saiplu
saiplca Horn c««iteit* of trfcauai
aad Biaiiislppl
PESTICIDES; ADIPOSE TZSSDE; BILK;
ORIIB) BIOACCOBOIATIOI ; BIPBEItl
COBPOOIOS; CBIOIIIATED BIDIOCABBOIS;
ABUBSAS) BISSISSIPPI
a) Both«t« liom lliboo aid Araico,
Portagal
b) Botk«r* ftoc Bragaica. faco,
Goacda, Porto, Tiana do Caitolo, Tila
Bial, and Tina, Portugal
e) Bothicc f roi Brora, Port«l*gc«,
aad Sctobal, Portagal
Saaplas tak«i in 1972.
PESTICIDES; DDT; DOB; DIBLD1II: U1K;
POBTOGAt
S or ray. t«it«ro Australia, 1970-1971
22 nunlng aothiri, «t *6-«6 kg,
liviag nithla a 30 ii radiu of
Porth, liit«CD Australia
BllSt PBSIICIDBS; AOSTBAtll; BDT;
DPS; DIBIDIIB; BBUCBLOBOBBBSBBB
a) Poolod saiplM, 1967
b) Poolod •aipll'l, 1968-1969
c) Pooled »aiple«, 1971-1972
BOM ID Stockkoli, S««d«a
PBSTICIDBSl POPOLATIOI BXMSOBIi
BXLK; DDT! DOB; BIOACCDBOLATIOIl
SIEDEI
2* he after parturition
19-35 rr old lotbcrs. DO history of
•xpoinro to posticidis. India
ODt) DDE; DOTt 8EXACBLOROCICLOBIXAIE;
LIlDAIEl BIOACCaaOLATIOIt PESTICIDE
B 831 DOES; BLOOD; BILK; IIDIA; ADOLTS;
IIIBOBI
BBPEBEICB
Strasuan, S.C.
Kutz. •-».
1977
Pisticido* Bonitoring
Journal I0(*|: 130-133
Kutl, F.H.
Strassian, S.C.
lobs, A.t.
1977
Pestlcid* Baaagomt
and Inmctieidi
R*ii*tanc«, Acadaiic
Priss, Inc., !•* York,
San Francisco. Lonion.
(pp. 523-5391
Graca, I.
Fernandas, A.n.s.s.
Boarao, B.C.
197*
Pesticides Bonitoriag
Journal 8(3): 1*8-156
Stacsy. C.I.
Thoias. B.«.
1975
Pesticides Boaitoring
Journal 9(2):6«-66
•estoo, G.
197*
Aublo 3(2)179-83
Siddiqnl, D.K.J.
Sazena, B.C.
Bhargava, A.K.
Seth. T.D.
(riskna Burti, c.l.
rutty, D.
1981
Environmental Bessarck
2»:2»-32
-------
Ethrlene, t«tr«chloro- (8 CI)
Bthene, tetrachloro- (9 CI)
!27-IB-«
C2-CM
BV 165.85. 8P 121 C
TISSDB
156
BiU
BXPOSDIE BOOTB
AIALTTICAL
BBTBOO
6C/NS
• OflBBR
OF CASES
«2
SAUCE
a) 0.9-6.3 ng/al
b) 0.0-03 ag/al
c) 0.7-26 ag/al
d) 0.1-2.5 ng/al
•) 0.«->19 ng/al
f) 0.1-»3 ng/al
RBI*
a) 2.52 «or- 2.13
Bg/al
b) 15.9 »or- 15.9
ng/al
e) 3. HI »or- 7. 13
ng/al
d) 0.79 »or- 0.7%
ng/al
•) 3.21 »oc- 6.02
ag/al
I) *. 10 »oc- 8.15
og/al
GENEBAL IBFOBBATIO*
a) BaroaBe, M, 6 saaples
b) J«rmr city, U, 5 8
C) Total a)-«)
DM to saall saapli alia and
nouaadoi aaapllng, data cannot b*
•ztrapolatcd to cot Ira population
Staiy aaasarad •ntlronacntal
pollitaat* In allk, avaluatcd ualng
allk la pollutant stadia* near
chtalcal aaaufactarlng plants and/or
ladostrial facilities, tddltlonal
data, O.S. aad foreign, c«*l«*«d.
rot additional Intotaatlon contact
Bnvlronaantal Protection tgancy.
Biposac* Evaluation Olvlsloa, Office
of lode Substance*, Rasklagtoa, DC
20i6l
Lactatlng >olnnt*ers, residing la
area >I2 ao, no tra»«l oat of area
doting preceding nk
LODISItIA; IB! JEBSBI; PEBISItf till)
•EST TltelllA; tDOlTS; IILK;
BBtSOiBHER BBTBODS: BBBtBBBS;
CB10BIBMBO BIOIOC1IBOIS;
CBIOBOBEBSBBBS; ODE I IIODSTBUL
UBaS| IBDPSTBItL KUSSIOIS;
UCttTXOB; PESTICIDE BESIDOBSl OBBaB
ABBaS; IBDOSTBIAL CBEBICALS; SOITEBTS
BEfEBEUCE
1 • • *
Erlckson, H.o.
Barrls, 3.s.n., in
Pelllzzari, E.D.
Toat-r, K.B.
Vaddell, B.D.
Uhltaker, D.».
1930
EPA &60/I3-80-029. 153
PP.
Btarlaaa. 1, l-dichloro-2-(o-cblotopaaarl)-2-(p-chlor>phenrl)- (SCI)
Benzeni, t-ckloro-2-(2,2-dichloro-l-(l-chlorophenrl)athenrl)- (9 CI)
3*2*-82-6
CU-BB-C1*
Bl 318.03
XISSDB
157
Haaaarr
gland
BZPOSOBB BOOTB
•
ABALTTICAL
HBTBOD
.
CC
6C-BC
BOBBEB
or CASES
al 5
b) 9
c) 9
RAIGE
a) 0.06-0.32 ppa
b) 0.3«-«.70 ppa
c| 0.07-1.47 ppa
(IEH
BEAI
a) 0. 1639 ppa
b) 1.8589 ppa
c) 0.5689 ppa
PAGE)
GEIBBAL IirOBBATIOl
a) Coatrol
b) flalignant
c) Breast tissue adjacent to
aallgaancT
Baligaant tissue, adjacent to
appatentlT norsal glandular and
adipose tissue of nine vosea iiltb
adenocacciaoaa of the breast,
obtained froa the A.c. Caaargo
Bospital in Sao Paulo. Raaaarr gland
aad adjacent adipose tissue ftoa 5
healthr noaen "ho dlad accidentally
used lot controls.
BBEAST; BABBABT OLAIDSJ IBOPtASBSj
ADIPOSE TISSUE; CABCIBOBAS;
PBSTICIDBS; UPIDS; CBIOBIBATBD
BTDBOCABBOBS; CBLOBIBB OB6ABIC
COBPOOBDSl BIOACCDBOLATIOB; BIPBBfU
COBPODIDS; DIELDIII: POLICBLOBIBATBD
BIPBBBTLS: DOT; DDE;
BBIACBtOBOCrCLOBEZABB; ODD:
IBPTACB10B EVOZIDB
BEFEBEICE
lassstaaaa, n.
logueira, D.P.
Toaatis, L.
Sirra, A.P.
Shlbata, B.
Arie, G.
Cucoa, S.
lasseraann, D.
1976
Bulletin of
EnTiconaeatal
Contaaiaation and
Toxicology
1S|4):«78-B8«
-------
Ethylene. I, l-dichloro-2-(o-chlorophenyl)-2-(p-chlorophanyl)- (8 CI)
Manna, 1-chloto-2- 12,2-dlcaloro-1-(H-chlocophenyllethenyl)- (9 CI)
3*.2«-82-6
Cia-88-CH
BB 316.03
(COBIXBOBD)
TISSUE
158
Bilk
159
Bilk
EXPOSOBE BOOTB
1I1LTTIC1L
BET BOD
OC
oc
tic
•DBBEB
OF C15IS
,
29
30
UIGE
lot given
l.6-«3.8 ppb
BE*B
0.0095 pp.
18.02 ppb
GEBEE1L IBPOIBITXOE
Biqher percentages of organochlorina
insecticides and PCB's la allk of
sothars 20-29 r«n than 10-39.
although the foraer had lomr leva la
In plaaaa. Ovnrnalght vosen had
lorar levels thaa noaen of noraal
•eight. Besidues concentrated in
extracted llpU* of plaaaa and ail It.
Israeli *oaea 2-» days aftac noraal
dallvacy.
PESTICIDES; BIOOO PL1SIU; BltX;
POPOtlTIOl BIPOSOIE; ISBIBI;
CUOBZBITED BTD10CABBOBS; LIPIDS;
lOIl DOT; ODD; ODB; POLICBLOBIB1TED
BIMBBTLS; BEFT1CBLOB EPOXXDB;
BBXaCBLOBOCICLOB EX» BE
Bilk aaaplaa, hoapltala In urban
Oalo. « aaaplaa froa Balllaqdal, a
Tallay in aonthaca locttar- Bo
occapatlonal azpoaara.
BZIB; XBSBCTXCXOBS) LtCTlTIOBl
CBtOBXBHBD BIDBOCIBBOBS; CHLOBIIE
OIQ1IIC COBPOOBDSj PESTICIDES; BOBRM
BErneicE
Pollahak, Z.I.
Bon, H.
Basaacaann, i.
Cocos, s.
Baasacnaon, D.
Laaaacb, C.
1977
Paatlcidaa Bonitorin.)
Joacnal 10 (1) : 121-129
Bakken, ».P.
Saip, n.
1976
tcta Paadlatclca
Scandlna*lca 65:53Ii-c39
Ethylana, I,l-dickloco-2,2-bla(p-chlorophanyl)- (8 CI)
Banxma, 1,1«-{dlchlotoathanylldene|bls<«-chloco- (9 CX)
72-55-9
CU-B8-C1B
BB 318.02, BP B8.« C
TISSUE
160
Banaary
gland
HPOSQU BOOT!
iULTTICAL
HBTHOD
CC
CC-EC
*
IOHBEH
OP CASKS
a| 5
b) 9
c) 9
BUGS
a} •.81-8.7*1 pp.i
b) O.M-6.61 pp«
c) 0.22-5.35 PP«
(MBIT
BE1B
a) 6.6697 ppa
b) 2.7U9 ppa
c) 2.0276 ppa
P10B)
OEBEItL XBrOBBlTXOB
a) Control
b) Ballgnant
c) Braaat tlaaaa adjacent to
aallgnancy
Taloaa capraaant tha concantration*
in aitractad llpidn.
Ballgnant tlaana, adjacant to
apparently nornal glaadnlar and
adipose tlaaae of nine tonen vitk
adenocarcinoBB of the breast.
obtained (cos the I.e. caaargo
Boapltal in Sao Paulo. Banaary gland
and adjacent adipose tlaaaa fron 5
healthy vonen *ho died accidentally
used for controls.
BBBaST; BiBBaBT GtiBDSt lEOPliSHS;
aDIPOSB TISSOE; CiBCXBOBISl
PESTICIDES; LIPIDS; CBLOBIBtTED
BTDBOCUBOBS; CBLOBXBB 08SAIIC
COBPOOBDS) BIOACCOBOUTIOI; BXPBEBTL
COHPODIDS; DIBlDill; POITCBLOEIBIIBD
BXPBBBTISi DDT; DDE;
BBIkCHLOBOCICLOBntBE; BBPTaCBLOB
BPOXIDE
BEFEBEBCE
Baseernann, B.
Bogaeira, D.P.
Tosatia, L.
Blcra, *.p.
Shlbata, B.
arle, 6.
cncos, S.
Haaaaraaan, D.
1976
Bulletin of
Environ aental
Contanlnation and
Toxicology
15(«) i»78-«8«
-------
S thy leu*, 1,l-dlchloro-2,2-bls(p-chlorophenyl|- (8 CI)
Benzene. 1,1'- (dichloroethentlldene)blB(>-chloro- (9 CI)
72-55-9
C14-H8-C14
Bl 318.02. HP 88.* C
(coiTiiOED)
TISSOE
161
Kllk
i
162
Hilk
163
HI Ik
. ,
16»
Bilk
16S
Bilk
166
Bilk
EXPOSOBB BOOTE
AIALITICAL
BETBOO
CC
OCSH3
_.
ce
OC-EC
TIC
BC
oc
6C
OC-BC
IDflBEB
OF CASES
•1 6
b| 9
6
a) 14
b) 59
c) 15
4) 97
>
2
2
•) 5
b) 5
RANGE
0.017-0.068 ppa
0.009-0.0*0 ppa
0.09-10.85 ppa
0.01-0.18 ppi
•) 90-93 ug/kg
b) 30-88 U9Yk9
c) 32-70 ug/kg
d) 21-8* ugAg
a) 29-32 ppb
b) (6-52 ppb
1.44-4.49 ng
a) lot given
b) lot given
USA I
a) 0.035 ppa
b) 0.019 ppa
a) 1.88 ppa
b) 0. 10 ppa
a) 65 ag/kg
b) 59 ugAg
c) 52 agAg
d) «a ag/kg
a) lot given
b) lot given
2.96 uj
a) 161 gaaaa/day
b) US gaaaa/day
GZEEEAL IIFOBNATIOI
a) lev Bronsvlck voaan
b) lora Scotia voaen
Sis lactatlng nothars fcoa la*
Bruosvick and 9 (COB io*a Scotia.
BILK; BkEASTi CAIAOA; PESTICIDES;
CB10BIIATEO RTOROCABBOISj CHLOBIIE
ORGAIIC CODPOOIDS; BIOACCOBULATIOI;
LACTATIOI; FOLICBIOBIIAIEO BIPBEIII.S;
ODT| DOE
a) Values are for alik fat
b) Values are for vhole silk
Sasples fros resldeats of aavaii
collected froa 1964-1973
PESTICIDES; BAIAII; FBTOS; fCTAL
HEBBBAIES; BILK; VTERaS; BLOOD SEBOH;
DDT; DDE; DIELDIII
a) Apr-July 1967
b) IOT 1971-Dac 1972
c) Jane-BOT M74
d) Bar 1976-Sar 1977
Back case represents a pooled saaple
froa 10-20 aotaers.
Sasples froa vosen in Stockholm,
S«eden
PESTICIDES; SSEDEI; MW; BIPBEIIL
COBPOOIDS; CBLOBIIE OSGAIIC
COBPOOIDS; CBLOBOBEIJSIIES;
POUCBLOIIIATED BIPBEinS; DIELD1IB;
DM; DDE; BEUCBLOBOCTCtOBBIAIE
a) Saaple I
b) Saaple 2
Bepeated detersinations
PESTICIDES; CBLOBOBEIZEIES; DDE; BILK
Aaoiuts varied for dlffereat
feedings. Talaes arc daily total.
Sasples f ros donors at various tlaes
of breast feeding and at different
tises of the day.
HIM; PESTICIDES; PESTICIDE 1ESIODES;
KUCB10IIIATZD BIPHCTYLS;
BIOACCDB01ATIOI; BBZACBLOBOBEIZEIE;
DDT; BBZACBIOROCICLOBBXABB;
BEPTACBIOB EPOIIDE; OZtCBLOBDABB;
IOIACHIOB; DDE; DIELDBII
a) Breast-feeding aothara Kith one
child
b) Breast-feeding aethers tilth tnlna
Data for 1974
Tvo groups of breast-feeding Bothers,
one group feeding one Infant and the
other group feeding twins.
PESTICIDES; CB10BIIB OBGaBIC
COBFODBDS; CBLOBIIATBD HTDBOCABBOIS;
BBEAST; IBFAITS; FOODS
Husial, C.J.
Hutzlnger. 0.
Zltko. V.
Crocket, J.
1974
Bulletin of
Enrironaental
ContaalnatloD
Toxicology
12(3| :258-2«7
ind
Kleaaer, H.u.
Budy, A.II.
Tanahashi, w.
Baley, T.J.
1977
Clinical Toxicology
•eatoo, G.
loren, X.
1978
Asbio 7(2) :62-60
BraTik, E.H.
1978
Bulletin of
Environaental
ContaaiaatioD and
Toxicology 19:281-286
D.J.
Bes, J.
Davies,
1978
chesosphere
7 (9): 699-706
Adaaoric, T.B.
Soklc, B.
salljanskl, B-J
1978
Bulletin of
EaTlronaantal
Contaslnstion and
Toxicology 20:280-285
-------
EthYlent, l,1-dichloro-2.2-bis(p-chlorophenvl|- (8 CI)
Benzene, t, ('-(dlchloroethenvlldene) bis(a-chloro- (9 CI)
72-55-9
CU-H8-C1H
«• 318.02. HP 8B.» C
(COITIROED)
tissue
167
•ilk
168
Bilk
169
Bilk
170
Bilk
171
Bilk
BIPOSOBB ROOTE
-
.
AULTTICaL
HETBOD
OC
.
OC
TIC
ec
GC
IOBBBB
OF CUBS
57
29
50
__T ..
36 of 51
a) 23
b) 20
c) 12
d) «0
e) 38
f) 19
91 20
b) 19
RANGE
._.
0.01-1.72 ppa
lot given
0.9-113.2 ppb
lot given
a) lot given
b) lot given
c) lot given
d) Mot given
e) lot given
f) lot given
g) lot given
h) lot given
(•BIT
mi
0.22 ppi
0.0217 ppn
65.10 ppb
0.035 ppi
a) 2.8 ppi, (
b) 2.1 ppi, <
c) «. 1 ppi. I
d) 3.3 ppi, 1
e| 3.8 ppn, 1
f) 3.7 pp«, (
g) 3.8 ppi, (
h) 4.0 ppi, 1
P16E)
fat basis
fat basis
fat basis
fat basis
fat basis
fat basis
Cat basis
fat basis
GBIEBAL IIFOBHATXOI
Lactating vosen in selected areas of
Arkansas and Blssisslppi.
BrW; PESTICIDES; ADIPOSE TISSDE:
IETABOLXTBS; CHLOBIIE ORG1IIC
COBPODIDS; CBLOBIfATBD BTDBOCARBOIS;
LICTATXOI; OIICHLOBDUE; POT;
IOIACBLOB; BEPT1CHLOB EPOXXDE;
DlttDFIIj BEUCBLOBOCTCLOBBXAIE: ODE;
ARKANSAS; BISSISSIPPI
Bigher percentage* ot organochlorine
iosecticide* and PCB's In lillt of
aothecs 20-29 fears than 30-39,
although the focner had loner levels
in plasaa. Overveight vonen had
lover levels than Honen of norial
•eight. Besldues concentrated in
extracted liplds of plasaa and ailk.
Israeli voien 2-» days after nornal
delivery.
PEStlCIDZS; BtOOB PUSBa; BIUC;
POPtlLlTIOl mosOBB; ISBML;
CBLOBIIaTBO HtOEOCiBBOIS; tlHOS:
aBIt DOT; DOOi DOB; MtTCBLORIIaTEO
BIPBEITLS; HEPIACHLOB EPOXIDB;
BBXaCBlOROCICLOB fZi IB
Bilk saaples, hospitals in urban
Oslo. * saiples froi Ballingdal, a
vallev In soathern lornar. lo
occupational ezposare.
BZlKt IISECIICIDtS; L1CT1TIOI;
CBtOBXIAtBO BTDIOCaBBOIS; CBLOBIII
OIMIIC COBPOOIOS; PESTICIDES; IOBIU
Bandoi subjects of greater St. Louis.
80, ntropollton area.
PESTICIDES; CBLOBIIE OBStBIC
COBPODIDS; DDT: DOB: DIILDBII;
BBUCBIABOCTCLOBEUIBi BBPflCBLOB
EPOXIDE; BILK; BXSSOOBIt COBPaBaTITB
BtalOaTIOIS
1) 1970
b) 1971
c) 1972
d) 1973
e) 197»
f) 1975
g) 1976
h) 1977
Bstiuted fcoa graph
Bothers in Osaka Prefecture
BIPBSR1 COBPOOIDS; CBLOBIIE OBOallC
COBPOOIOS; DDE! DDT; DIELDBII;
BEXaCBLOROCiaOBIXaEE; JkPM: BlUt;
POITCBIOBIIaTBD BIPBBITLS
BEPEtEICB
KutZ. P.H.
Straassaa, S.c.
lobs. 4.B.
1976
International Workshop
on Biological Speciifto
Collection. Ipril.
1976. Luxembourg
Polishuk. 2.H.
Bon. H.
•assersann. n.
Cncos, S.
lasseriann, D.
Leiesch. C.
1977
Pesticides Honltoring
Journal I0(«l : 121-129
Bakken. a.F.
Seip, B.
1976
acta Paediatrlca
Scaadinavlca 65:535-539
Joasson, V.
Lin, C.J.It.
arabruster, J.
Kettelhnt, L.L.
Drucker, B.
1977
anerican Journal of
Clinical lutrition
30:1106-1109
Takoshili, T.
latanabe, I.
Knvabara, K.
Toshlda, S.
Bori. S.
Pukashisa, S.
Rashiaoto, T.
Kovasa. K.
Konita, 1.
1979
Archives of
Bnvironnental
Contasinatioa and
Toxicology 8:59-66
01
-------
Ithrlene, l,1-dlcaloro-2,2-bia(p-cblorophenrl)- (8 CI)
Benzene, I, l«-(dichloroethenylideoe)bia(»-chloro- (9 CI)
72-55-9
CU-H8-C1H
HI 3*8.02, tit 88.« C
(COItllOSD)
TISSOB
172
Bilk
173
Bilk
m
Bilk
175
Bilk
BSPOSOIE BOOTS
aULTTICll
BEIHOD
6C/P1S
GC-8C
GC/BS
IDBBBI
or CUBS
1) 10
b) 25
C| 35
4) 10
•) 20
f) lot
given
10
25
lalGE
•) Mot given
b) lot given
C) lot given
d) lot given
e) lot gl»«o
f) 1-1 1« no/q
«2. 0-418.5 u
-------
Btbyleae, 1, l-dlchloro-2.2-bls(p-CBloropheayl)- (SCI)
Benxenc. 1, 1 •- (dlchloroothenylldene) bis («-cbloro- (9 CI)
72—55—9
CU-BS-C14 '
HI 318.02, HP 88.* C
(COBTIBOBD)
TISSOB
176
Bilk
1T7
fltlk
178
• 4 fk
OeV&JL
"•"*-
179
Ulk
EXPOS OBE BOOTE
Xngestion
*
inLTTXCftL
HBTBOD
GC
GC-BC
GC
cc/iis
—
EDRBEB
or cists
•1 21
b) 2*
c) »5
d) *S
IS*
50
5
BIBCE
•) 0.935-26.106 pps
b) 0.535-13.107 ppa
a) 0.535-26.406 ppa
d) lot given
•) 0.01-6.79 sg/kg fat
b) lot given
c) Bot given
260-5700 ppb
a) 45-73 ng/al
b) 38-101 ng/sl
c) 38-101 ng/sl
BE* I
a) 6.698 ppa
b) 5.833 pp»
c) 6.263 ppa
d) 0.11* ppa
a) 0.883 »or- 0.773
ag/kg Cat
b) 0.58 «or- 0.35
•g/kg lat
c) 0.99 »or- 0.99
•g/kg fat
2000 ppb
a) 59 ng/al
b) 78 ng/al
c) 71 ag/al
GENEBIL I«rOKB»IIO»
a) Bacal lotbecs. fat bail*
b) OcbiD aothacs, fat bail*
c) all (other*, fat baals
d) »ll aotbacs, vkol* ailk ba*i>
Data foe «o» of all p»tlotd*s aod
coipaclaou «ltk raliws of otk«t
investigator* gl**o
Inratag actbcra fcoa Cordoba cagioa.
Spain
sen*: iDOLTs; HIM: CBIOBIBB OBCIIIC
COWOOBOS; PBSTICIDESj lOBXCOLTOBB;
BOBU aBBISi OBBiB ABBaS
a) 15* *aapl**, 0.032 »or- 0.028
ag/kg «hol« ailk
b) Bual ra«id*nt*, 19 aaapl**
c) Urban r«*id*nt«, 51 «aapl«*
3-6 day* poatpacttfa. Blghar !•*•!•
Kith aaoking and urban r««id«nc«
18-38 yr old*. Canada
11DBII; CtBADIl ME; BILK; CR10BIBE
OBG1BIC COBPOOIDSJ ODB; DDT;
BBIACBUBOCICIOBEUBES LIBDlBBl
POUtCBLOBIBaTEO BXPBBBIU; POP011TXOI
BIPOSOBB! iOBil 1BB1S; 9BOKIBQI OBBAB
1BEIS
Eztractad llpid*. Jan 1979 to Fab
1980, 3-* 6 days poatpartaa. Bo
significant correlation with
CMidanc*, age. Height, naaber of
children preTioaaly naraed, hoaaehold
as* of non-pscsistsnt paatieidaa, or
ocenpatlon of *po«ae. Bigher, bat
nonsignificant levels in voaan »lth
higher Cregaency of Mat consnaptioa.
and in those in hoee* litk pest
control treataent.
Bealthy 18-37 yr old Bavallan*
aODltS; »SBi Bivill; RUB;
CBLOBII1TEO BtOBOClBBOBS« DDE; DDt;
OIBtDBIB) BBMCBLOaOCIClOBKUB;
aimcnoB BPOZIDBI
BBXtCHlOROBBBZElE: UBDtBB;
BOBtCBLOBt OnCBtOBDkBBt PBSIICIDBS;
P01TCBLOBIB1TBD BIPBBBILSl DIETS;
LlCtUIOVl PESTICIDE BBSIDOBSl
POPOLHIOB BUOSOBE
a) Pittsburgh, Pi, 2 saaples
b) Charleaon, IT. 3 Maple*
c) Total, a)-b)
Selected saaples
Lactatlng folontears, residing in
area >I2 *o, no tr«»el oat of area
daring preceding vk
LOOISIlBi; BEN JBBSEI) PBBBSTlTiBIt;
BBST TIBOIBIt; »OOLtSj BIIK!
BBiSOBBBEBT BETBOOS; BBBIBBESl
CBLOilBitED BIDBOUBBOBSl
CBLOBOBEBIBBBS; DDE; IBDOSTBUL
UUS; IBDOSTBXtl EBISSIOBSl
UCtltIO»! PESTICIDE BBSIDOBS; OBB1B
1BB1S; IBDOSTBItL CBEBICltS; S01TBBTS
kPPEBEICE
Poza Lara, B.
Berreca Hacteache, ».
Polo rillac, L.d.
Lopez-Glaenex, B.
Jodral Tillarejo, X.
Igleslas Pervz, J.
1979
Batista Espauola Ju
Pediatrla
35(206) :93-110
Dillon. J.C.
Bartin. 6.B.
O'Brien. H.T.
1981
Food and Cosaetics
Toxicology l9:«37-««2
Takahashi. H.
Saidla, D.
takei, 6.
Bong, L.
1981
Balletln of
Environmental
coataslaatloa and
toxicology 27:506-511
Brickson, B.D.
Harris, B.S.B., HI
Pelliixarl, B.D.
Toner, B..B.
(addell, B.D.
Ihitaker, D.k.
1980
BPa 560/13-80-029, 153
PP.
(MBit PiSB)
-------
EthTlane. 1.l-dlchloro-2,2-bl*(p-c61orophenYl|- (6 CI|
Benxene. 1, l'-{dichloroethenyllde*e)bls<«-cliloro- (SCI)
72-55-9
CI«-B8-C1«
HI 118.02. HP 88.« C
(COITIlagD)
TISSOE
180
Bilk, fat
181
Bilk, fat
182
Hi Ik. fat
183
Bilk, fat
184
Bilk, fat
EXPOSURE BOOTS
, , .
ANALYTICAL
BETBOD
GC
GC-SC
GC-EC
GC-EC
IDRBEB
OP CASES
al l«
b) 5
c| 18
a) 53
b) 33
a) 3«
b) 6
BAIGE
lot given
a) lot given
b) lot given
c) lot given
a) 0.173-8.12 ppa
b) 0.258-5.18 ppa
a) 2.46-73.83 ppa
b) 1.47-2.45 ppa
a) lot given
b) lot given
c| lot given
d) lot given
e) Hot given
f) lot given
HEAI
4497 ag/kg
a) 2.0 ag/kg
b) 1.7 agAg
c) 1.9 ag/kg
a) 2.23 ppa
b) 1.09 ppa
a) 14.67 ppa
b) 1.920 ppa
a) 1.71 » or - 0.88
ppa
b| 1.98 » or - 1.51
ppa
c) 1.94 * or - 1.04
ppa
d) 1.92 * or - 0.79
Ppa
e) 2.02 * or - 0.99
f) 1.60 * or - 0.64
ppa
GEIEBAL IR'ORHATIOI
85 saaplea-each is average froa 20
aethers. Bilk obtained froa lactaria
la Slovakia. 1971-1973. Values
estlaated froa graph.
PESTICIDES; BILK; PATS:
CZECHOSLOVAKIA;
BEXaCBLOIOCYClOBEXAlE; DDT: DOS;
BBXaCBlOROBEIZEIB
a) Pooled saaples. 1967
b) Pooled saaple*. 1968-1969
c) Pooled saaples. 1971-1972
Voaen in Stockkola, Sneden
PESTICIDES; POPULATION EXPOSURE;
BILK; DDT; DOE; BIOACCOBULATIOI:
SIEDBI
a) 1966-1970 study
b) 1977-1978 study
1966-70 patients (University of
Alberta Hospital), 2-10 days
postpartuu. 1977-78 patients (public
health offices of Alberta), 17-309
days postpartua. Residences, Edsoatoa
or Alberta.
BI1CI PESTICIDES;
BBXACBLOIOCTCIOBEXAIE; ODD: DDE; DDT;
DIELDRIB; BEPTACBLOI BPOXIDE;
BMACHLOBOBBIZEIE: CAIADA;
POITCBLOBIIATED BIP8EITLS;
COHPAIATIVE EVALDATIOIS
-
a) Bigh pesticide usage area
b) Low pesticide usage area
loses living in Stark villa.
Bisslssippl (lo« pesticide usage) and
Delta area (high pesticide usage).
Sasplea in 1973-1975.
BILK: PESTICIDES; DDE; ODD; DDT;
BEXACBLOBOCTClOBEXAIEt BEPTACBLOI
EPOXIDE; OXXCBLOBDABB; DIBLDRTI;
BISSISSIPPli COBPABATI'B IVALOATIOIS;
BBASUREBEBT HETHODS
a) 1972, 40 saaples
b) 1973, 38 Maples
c) 1974, 19 saaples
d) 1975, 20 saaplas
e) 1976, 19 Maple*
f) 1977, 20 Maples
100-141 lactatiag voaen, 2 souths
after delivery. Residents of Osaka
Prefecture, Japan, varied diets and
enviroasental conditions.
JAPAl; ADULTS; LACIATIOI; BILK:
BIOACCDBULATIOl; PESTICIDES; DDE;
ORGABIC CB10RIIB COBPOOIDS;
POIICBLOBIIATED BIPBEIILS
EEPEBEICE
Szokolay. ».
Rosival, L.
Uhnak. J.
Hadarlc. A.
1977
Ecotoxicologr and
Eavironaental Safety
1:349-359
Veatoo. G.
1974
Aabio 3(2):7»-83
carri*. B.A.
Kadis, V.I.
Breitkreltz. I.E.
Cnnnlnghaa, G.B.
Brans, G.v.
1979
pesticides Bonitoring
journal 13(2|:52-55
Barnett, H.I.
D'Brcole, A.J.
Cain. J.D.
Arthur, R.D.
1979
Pesticides aonitoring
Journal 13(2) -.47-51
Takeshi]!. T.
latanabe, I.
Kuwabara, K.
loshida, S.
Koyaaa, K.
Knaita, f.
International Archive*
of Occupational and
Eavlronaental Health
43JI-15
• "" " _..-...,. (BBXT P1GB)
-------
1.1-dichloro-2.2-bis(p-chlorophen7l}- (8 CI|
Banana, I, I'- (dichloroethanylidane|bis(a-chloro- (9 CI)
72-55-9
CU-Hfl-Cla
HI 318.02, BP 88.* C
(coETiioeoi
TISSDE
185
Bilk.
•hole
186
Bilk,
•hole
187
Bilk,
•hoi*
IBS
Bilk.
•hole
189
Bilk,
•hoi*
190
Bilk.
•hoi*
EIPOSOHB BOBTE
1I1LTTIC1L
BBTBOD
GC-EC
tic
GC/BS
GC-BC
6C-BC
OC-BC
ac
oc
nc
BDBBBB
or CISBS
57
57
a) 3»
b| 38
e| 39
4) 5«
22
a) U
b) 5
e| 18
25
UBGB
0.01-1.72 ppa
0.01-1.72 ppi
- - . -- Ll-r
a| 0.025-0.516 pp*
b| 0.006-0.109 pp*
e| 0.019-0.699 pp*
d) 0.007-0.282 pp*
0.015-0.112 pp*
•) lot given
b) Bot giT*n
c| lot given
0.0095-0.1590 pp*
REll
0.227 pp*
0.22 pp*
•I 0. 178 pp*
b) 0.035 pp*
c) 0.220 pp*
d| 0.095 pp*
0.061 pp*
•) 0.065 *g/l
b) 0.052 »g/l
e| O.OS9 ag/1
0.0717 »or-
PP*
s.s.
f
GEREB1L INFORB1TIOE
S**pl*« f roe 17 B*gco** **d «0
C*ae**i*a* in hospitals in Ickanns
•ad Bi*«i*alppi.
PESTICIDES; PESTICIDE BESIDDBS; HI Lit ;
BIOICCOBDL1TIOI; WPOUTIOB BIPOSOBE;
BimtlT OliiDS; L1CTUIOB; PtACERTl;
•BIttBSIS: HISSIS3IPPI
I00( pocitl** *a*pl**.
S**pl* fco* l*ct«ting *o**n in
selected *c*u of IrkuiBia and
Hiniraippi.
PESTICIDES; UIPOSB TISSOB; BILK:
OBIIB: BIOlCCaaOLMIOl! BIPRBBTL
COBPOD10S; CHIOS III TED BTDBOCIBBOBS;
1RUBS1S; BISSZSSIPPI
•I Bothcc* fro* iniro. Poct*l*gra,
•*d S*tab*l, Portogal
b) Batbic* fro* Tia*a and Braganca,
Poctagal
c| Both*E* f co* ETOca and U.*bon,
Portugal
d| Bother* fro* Paro, Goacda, Porto,
Tiana do CMtelo, and Tlla leal.
Portugal
Saaple* take* in 1972.
PESTICIOBS; BOX; DOB; DIELDBII: BILK;
POBTOOal
SOEMJ. lutaro tutnlla. 1970-1971
22 nursing aotber*, vt 46-66 kg.
living •ithin a 30 *1 radios of
Perth, Bestora »a*tralia
HUB; PBSTICUES: 10STE»LI»! ODT;
DDE; DIB1DBIB; BBIkCBIOBOBBBZBIE
•I Pooled uiple*. 1967
b) Pooled Miplas, 1968-1969
c) Pooled s**ple*. 1971-1972
•OMB in Stockhol*. s»edea
PESTICIDES; POPOHIIOI BZPOSOBB;
BIU{ DDT; DDE; BIOlCCOBOLlTIOB;
SBBDBB
2* he after parturition
19-35 yr old aothara, no hiatocy of
ezposare to peaticid**. India
DDE; DDE! DDT; HEIiCHLOBOCICLOHBtHE;
1IBD1BB; BI01CCOBOL1TIOB! PESTIdOE
BBSIDOBS; BLOOD; BILK; IBDIi; tDOLTS;
BBIBOIB
BErEBEICE
Strasaaan, S.c.
Kntx. r.B.
1977
Peaticide* Ronitoeing
Journal 10 (*) s 130-133
Kutz, P.R.
Strasanaa, S.c.
Toba. l.B.
1977
Pesticide Banageaent
and Insacticid*
Resistance, tcadeeic
Press, Inc., !*• York,
San Francisco, London.
(pp. 523-5391
Graca. I.
Fernandas, l.B. s.s.
Bourao. B.C.
197a
Pesticides Bonitoring
Journal 8 (3|: 1*8-156
Stacey, C.I.
Thoiaa, B.R.
1975
Festicides Bonitoring
Journal 9 (2) : 61-66
Bestoo, G.
197«
labio 3(21:79-83
Siddigni, B.H.J.
Sazeoa. B.C.
Bhargara. l.K.
Seth, T.D.
Kciabna Bartl, C.R.
Katty. D.
1981
B»*iron**ntal Research
2*i2«-32
-------
Flaccid*
t698«-«e-B
t
Atl 18.998*
TISSDB
191
Bilk
,-
192
Bilk
1
EXFOSOHB BOOTB
,_
Inhalation
AlAlYTICAt
HETBOD
IOBB1E
OF CUBS
BAIGE
2.1-15.9 ag/dl
a) 2.4-7.8 OH
b) 38.0-85.0 an
mat
1st 9 If en
t) Dot given
bl lot given
GEHE64L INFOBBATXOI
•OMB in Biralnghae. Bristol,
Cardiff. Edinburgh, and levcaatle.
SODIDH: nooiiit; IODIIE; BBTALS;
UU) OBITED KINGOOB
a) laocgtolc F
b) Organic F
L*nl« 21.S-M.5 hr afttr
a«thoiTflac*D* «•• qifcn a«
an«atk*tic daring labor.
Patient at a tocfeatar, IT hospital
B806S| FLOOBIBE CORPODIDS;
ICUBOLITES; BLOOD; BILK; IIFlIfSj
ici tosrj ADOITS
SEftKEHC!
Anon
1977
Lancvt I(8017):«IH
Fry, B.I.
Ta»s( D.B.
197*
Isarican Journal of
Obstetrics and
Gyoecoloqr
119(2) : 199-20*
Bexachlorobanzol (Bo postings in CBBBLIIB).
fISSOB
193
Bilk
BSPOSOBS IOOTE
, ,.
aBallTXCil
BBTBOD
GC
TIC
, _
BDBBBB
OF CASKS
a) 50
b) 15
c) 6
BalGE
a) 1.7-60.5 ppb
b) lot given
c) lot givsn
BBAI
a) 9.7 ppb
b) 7.7 ppb
c) 10.0 ppb
GBIEBAL IIFOBIUTXOI
a) all saaplu
b) Colostros
c) 9-16 *k after birth of infant
Bilk aaaplea. hospitals in orbao
Oslo. « aaaplea fros Ballingdal. a
TSll«)r la aoathern larnay. Bo
occupational eipoaare.
Bill; IISECtlCIDBSi LACTATIOI;
CSLOBXItTEO BIDBOCARBOISj CILOBXIE
010 A nc coflpoaios; PESTICIDES* WBIAT
BEFEBEDCE
-
Bakken. A.r.
Seip, H.
1976
Acta Paediatrica
Scaadinarlca 65:535-539
Iodide
20«61-S«-5
X
Atl 127.9
TISSDB
19*
Bilk
EIPOSOBB BOOTB
AIALTTICAL
BETBOD
IDBBEB
OF CaSBS
UIGE
2-12 ag/dl
BEAI
lot giren
GEIBB1L HFOBBATIOB
•oaen in Biraiagbaa. Bristol.
Cardiff. Edinburgh, and lereaatle.
SODXOB; FLOOBXIE; XODXIE; BBtALSJ
SO.fl OBITBD KIIGDOB
BEFEBEICE
Anon
1977
Lancet I(80I7(:9I8
-------
Itoa
7*39-89-6
Pe
itl 55.8*7. HP 1535 C (pace). 1000-1300 C (cut). 1500 C ((caught), 1300 C (steel) . BP 3000 C. »p 1 •• Bg at 17BJ c, 10 BB Bg at 20*0 C
TISSOE
195
Bilk
196
Bilk
197
Bilk
198
Bilk
EXPOS01B IOOTB
-
IMLTTXClL
RETBOO
its
ilS
us
IOB8H
or CUBS
50
•1 28
b) 39
c) 23
d) 13
e) 28
f) 30
IS
HUGE
Less than 0.1-1.6 og/sl
a) lot given
b) lot given
c) lot given
d) Hot given
•) lot given
f) lot given
0.26-0.73 ag/nl
BEil
0.21 •]/•!
a) 0.*9 * or - 0.0?
ng/Bl
b) 0.*3 » DC - 0.0»
ng/sl
e) 0.*2 » or - 0.06
ug/«l
1) 0.38 * or - 0.05
ng/sl
•) 0.39 » or - 0.09
ug/al
f) 0.«2 • or - 0.08
og/«l
O.*t og/al
GEIEBll IIFOIMTIOI
iaalr*i« of variance mggests one
•anple of nilk/inlividdal does not
Fcovide a cepcesentative esticate of
Pe content. Oat* given foe
variations bv aatecnal aqe. pacitv.
lactation history and for several
eiperlnental periods.
Sasples fros Pennsrlvanla sothers.
•2 sobjects Here betveen the ages of
20 and 30, vhile 8 vere over 30.
til subjects had healthy, fall-tern
infants.
COPIES; itoi: txic; mils; HIIEB*LS;
BETtBOLISB; L1CTAT10I; DIETS; BILK;
INBOB1; PEIISILVAII1
a) 1-3 eo lactation
b) «-6 no lactation
c) 7-9 no lactation
d) 10-12 no lactation
e) 13-18 no lactation
f) 19-31 no lactation
•hits Hoaen, 19-42 yr age, 22
pcialparae and 16 naltiparae.
B1000 SEEOB; BILK; BETiLS; LaCTHXOI;
BUI: C4LCIOB; BMIBSIOB; BIKIIESE:
1101; COPPER: ZIIC
0.1-19 no post parton. 15-»6I bmad
to lipid fraction.
Healthy Snedish nothers.
Bill; HOI; BBtalS: SIEDE1; MICE
BLEB El TS
levies. Research leading to present
understanding of husan requirements.
BIOICCDBDLKIOI; DIETS; POOD
1DDITITES; FOODS; LiCTlTXOI;
BBISTB01TXOI: PBBGlilCT;
ItOIOISOTOPES; RATS; PIGS; IBOI;
BBXUS; BLOOO) BOOT; HaXli LXTBR;
BILK; liltS; SKII; SPLEEl; OBIIB;
BBTIBI: iDOLBSCBITS; IDOLTS; tOB;
CULDIBI; IIP1ITS; 1IEBI1
BBFEBEICE
Picciano, B.r.
Gathrie. H.i.
1976
aeericu Joornal of
Clinical Intritien
29:2«2-25»
-
Vanghan, L.I.
leber, C.I.
Keaberling, S.B.
1979
tnerican Jonrnal of
Clinical latrition
32x2301-2306
Franssor, G-B .
tonnerdal, B.
1980
Journal of Pediatrics
96 (3): 380-38*
Severing, J.
Sanchez, ».B.
Xrvin, B.I.
1976
Journal of lutritioa
I06(7):985-I07«
-------
L-A>corblc acid
50-91-7
C6-BB-06
HI 176.12, HP 190-192 C
TISSDE
199
Bilk
El MS DEE BOOTS
. . ., ,. ,. .
ABALtTICAL
HEtBOD
BOHBEB
or cists
..
HICK
GEIEE1L XIPOBBATIOB
Batiav. Beaaarch laading to praaant
undaratanding of fcuaan raguiraaaata.
Data on satacatlon lerala In plaaaa,
aarai and vblta blood cells. Lafala
In body, ailk and at la* a Ho
taportad.
GOXBBA PIGS; ADOLESCEBTS; ADULTS;
tOI; CHILDfcBB; IHPABTSl SEX: OBAL
DISEASES: SKIM DISEASES; BLOODS BDDI;
Hiu; OBIBE; DBOGS; OBAL
COBTBACEPTIVES: BETXSil; VITAUB C;
DIETS; FOODS; LACTATXOBi
HEBSTIOATIOB; METABOLITES; PBBGBAUCT;
BADIOISOTOPES; SBOKIK
BEFEBEBCE
levin, i.l.
Hatching, B.K.
197C
Journal of Vatritlir.
106(6):823-879
Hagnaalaa
7»3S-95-«
19
Jltl 24.305, HP 651 C. BP 1100 C, If 1 aa Kg at 621 C, 10 aa Hg at 7*0 C
TXSSOE
200
Bilk
201
Bilk
EXPOSDBE BOOTB
IMLITICit
HETHOD
liS
US
IOHBEB
OP CASES
a) 28
b) 39
c) 23
d) 13
a) 28
f) 30
a) 76
b| 77
c) 23
d| 78
•) 29
BAIOB
a) Dot gi»«n
b) Hot 9 If an
e) Bot glvan
d) Bot gi»eo
•) Hot gl»«n
f) lot given
a) Bot gl*«a
b) Bot ijlran
e] Bot 9i»en
d) Bot giren
•1 Bot gt»«n
BEAR
a) 31 » or - 1.7
»9/al
b) 37 » or - 2.7
ag/al
e) 26 » or - 3.3
og/al
d) 29 » or - «.7
ag/al
a) 30 • or - ».6
ag/al
f) 26 » or - 5.1
ag/al
a) «0.38 ag/al
b) 31.65 ag/al
c) 29.13 ag/al
d) 32.0 ag/al
e) 29.0 ag/al
GEBEBAL XBPOBHATIOB
.
a) 1-3 ao lactation
b) 4-6 ao lactation
c) 7-9 ao lactation
d) 10-12 10 lactation
a) 13-18 ao lactation
f) 19-31 ao lactation
Shit a noaan, 19-42 rr ag«, 22
pcialparaa and 16 aoltlparaa.
BLOOD SEIOB! BILK; HEIALS; LACTATIOB;
BAH: CALCIBH; BASBESIOBt HABGABESE;
IBOB; COPPBB; ZIBC
a) Coloatraa, high and lo* incoaa
groups
b) Aftac lactation 1-3 aontha, high
and low incoaa groapa
c) Aftac lactation > or - 13 aontha,
high and Ion iacoaa groapa
d) Aftar lactation 1-3 aontha, lo»
Iacoaa group
•) Aftar lactation 1-3 aontha, high
Incoaa groap
Additional data awilabla. Bo
algnificant dlffaranca batvoan incoae
group*.
loaan fcoa arbaa and rural India.
BBTALS; TBACB EtlBBBTS; COPPEIi
HAGBBSIOB: ZIBC; BILK; COBPABATITB
BTALDATIOBS; OBBAB ABBAS; BUBAL
ABBAS; IBOIA
BEPEItEBCE
Taaghan, L.A.
(abar, C.I.
Kaabarllng, s.B.
1979
Aaarlcan Journal of
Clinical Butrition
32:2301-2306
Bajalakahai, K.
Srikantia, s.s.
1980
Aaerican Journal of
Clinical Batrltion
33:664-669
-------
Banganasa
7«39-9«-S
Bn
AM 5*.9380. HP I2«« C, BP 209S C. »P I aa Bq at 1292 C. 10 » Bg at 1510 C
tissoe
202
II ilk
203
Bilk
20*
Milk
EZPOSOBE BOOTI
-
XngastioD
AVALTTICIL
BET BOD
AAS
BOBBEB
OF CASES
.
a| 28
b| 39
c) 23
i| 13
•1 28
It 30
BAIGE
a) lot glvaa
b) Bot givan
e) Bot gl»aa
d) Bot gl»«n
•) Bot givan
() Bot gl»«n
BEAB
a) 1.98 » or - 0.21
ug/100 al
b) 2.38 » or - 0.33
ug/100 al
O 2.53 * or - 0.39
ug/100 >1
d| 1.75 * or - 0.27
ug/100 al
•) l.«l » or - O.SI
f) 1.99 » or - 0.86
ag/100 al
GEMEBAL XiFOBBATZOI
a) 1-3 ao lactation
b) •-« ao lactation
c) 7-9 ao lactatioa
d) 10-12 ao lactation
•) 13-18 ao lactation
t) 19-31 ao lactation
Hhita itoaen, 19-*2 jr age. 22
prlaipatae and 16 Baltipacaa.
BLOOD SBBUfl: BILK; BBIALS; L1CI1TIOB;
BalB: ClLCIOBj BaGBBSIDB; BkBBiBBSBi
IBOB; COPPBB; ZIBC
B«ian
IETI2I; BBTILS: TRACE BLBBBIIS;
COmt: BIB«ABBSB; SBLBIIOB;
CIQOBIOB; BBBBOBB; FETOS; BLOOD
PL1SB1; BBITBKOCTTBS; BILK; LIVBB;
DUTED KIBGOOB: BOTBITIOBaL
OCnCIBBCIBS; ABBIOtIC FLO ID
BaviBv. Profila of aaaltar mbjKti.
Baaalioa data (or datvcaialng changes
IB natritional atatos .
(aabacliag, S.p.
1979
Aaacican Joacaal of
Clinical latcition
32:2301-2306
Shan, J.C.L.
1980
Aaarican Journal of
Dlaaaaaa of Children
131:74-81
Cathria, B.B.
Eobinson. B.f.
1978
!•« Zaalaad fladical
Joacnal 87 (603): 3-8
Mrcorr
7*39-97-6
Bg
AtS 200.59, HP -38.87 C. BP 356.72 C. TP 2ZIO(B-3) aa Bg at 25 C, 100 aa Rg at 260 C
TISSUE
205
Bilk
iZPOSOBE BODTE
lagaatlon
ABALTTICAL
BBTBOD
AAS
BOBBEB
OF CUBS
__
76
BABGE
a) lot glvan
b) lot giTan
(•BIT
BBAI
a) 7.6 ng/al
b) 3.3 ng/al
PAGE)
OBBBBAL IBFOBBATIOB
a) coastal area
b) Urban araa
Saaplaa (ton 38 aatarnal-lnfant paira
froa Anchoraga and tha
tnkon-Kukokvia Delta aoapitalliail
tor childbirth.
tffacta on naabora naight or vital
algna not a*idant.
BBiCOBI; BBVBOIBl PBBOMBCT;
PLACBBtA; BBtALS; FOODS; FISBBS;
SBAIS) BLOOD PtASBAl BiTTBEOCITES;
BILK; B1IB; IBFABTS; ALASKA; DIRS;
BIRDS
IBFBREBCB
Galatac, I. A.
1976
XBTicouaatal Baalth
Puspactl*«B 15: 135- HO
-------
Bercary
7*39-97-6
Bg
at« 200.59, HP -38.87 C. BP 356.72 C. It 2110(8-3) an Hg at 25 C, 100 •• Hq at 260 C
(COITXXOED)
TXSSOE
206
207
Milk
208
Hlllt
209
Bilk,
vhole
BtPOSnae BOOTS
Ingestion
Placental
Xagestioa
AVALITXCAL
BETBOD
iiS
us
us
BORBE8
OF CiSES
32
3*
3«
Since
Hot given
0.1-9.8 ppb
0.1-9.8 ppb
BEAR
0.93 ppb
3.6 ppb
3.6 ppb
GERER1L XIFORBATIOH
100 saternal-aabilical cord blood
pairs, 38 placentae, and 32 breast
silk saeplea froa patients at tbe
university of lout Hospitals.
BLOOD: OHBILXCAL coso; LACTATXOH;
BBEAST; BILK; BEBCORT; BETALS;
PLICEHTi; 10 Hi
Levels represent background of Bg in
breast silk of Japanese nosen.
study at Suaida Obstetric Hospital
and oshisa Clinic of Toko University,
Tokyo, Japan, July - Roveaber, 197«.
OBBil AREAS; HERCORT; HBtHYl BBRCDRT
COBPOORDS; DIETS; BETALS; JAPAH;
FET0S: BLOOD; BILK; BAXR
._
Review. Bercary poisoning la
pregnancy, data based oa sources of
coataalaatloB, asternal uptake, and
distribution.
flental confusion, convulsion*, C COBS
IB adolts. Chi Id ran born «itb brain
daoage, chorea, atazla, tresors.
selsores, and seatal retardation.
lOiAj IRAQ; JAPAB: 1EI BUICO;
SIEDEI; TBRHESSBE: FEIOS; XBFABTS;
BBBTAL RETUOATXOR: BBTiL POISORIRG;
ABIXOTXC FID ID; BLOOD; BOOT; BRiXH;
BAXR; nii.lt PLACEBTA; ORXBE; HEBCOBI;
BETALS; BXOaCCOBOUTXOH; DBXBKXBO
IATBR; FOOD COHTAHIHATIOR;
IHBiLlTIOB; LiCTATIOI; PBBCRARCr;
Levels represent background of Bg in
breast silk of Japanese noaen.
study at Snalda obstetric Bospital
and osnlsa Cllaic of Toho Onlversity,
Tokyo, Japan, July - Bovcaber, 197*.
OIBAH AREAS; HMCORI; BETBIL BERCORT
COBV00103; DIRS; BETALS; JAMB;
PROS; BLOOD; BILK; Ball
REFEREICE
Pltkln, R.B.
Bahna, J.A.
Filer, L. J. , Jr.
Reynolds, I. A.
1976
Proceedings of the
Society for
Experlsental Biology
aad Bedicine
151:565-567
Fujita, fl.
Takabatake, E.
1977
Ballet in of
Envlronaeatal
Contaalnation and
Toxicology
18(2) :205-209
Koos, 8.J.
Longo, L. D.
1976
Aaerican Journal of
Obstetrics and
Gynecology
126(3) :390-»09
Fujita, B.
Takabatake, R.
1977
Bulletin of
Environaantal
Contaalnation and
Toxicology
18(2|:20S-209
-------
Betkylaalfone PCB (Mo poatiaga in CBMLXIE).
TISSOE
210
Bilk. fat
EXPOSOH BOOH
amnxctL
HBIHOD
sc
, L - - -
•DHB2B
or CASES
1
HICB
_
a) lot applicable
b) lot applicable
c) lot applicable
d) lot applicable
e) lot applicable
f) lot applicable
9) lot applicable
a) lot applicable
i) lot applicable
HB*I
a) 0.59 ppa
b) 0.77 ppa
c) 0.7* ppa
d) 0.61 ppa
e) 0.37 ppa
() 0.17 ppa
9) 0.22 ppa
h) 0. 17 ppa
i) 0.15 ppa
GEiBBai iiFOBiiTioi
a) aag, 1975
b) Sept. 1975
c) Oct. 1975
d) Dec. 1975
e) Feb. 1976
f) Ape, 1976
9) Jane, 1976
h) aag, 1976
i) IOT. 1976
Saaplea (COB a roaan nko kad Coraerly
been employed IB a capacitor factory
for font jean haadliag Ranechlor
(KC| 300 and 500.
CHLOBIIE OB61IXC COBPOOIDS;
BBMBOLXTBS; IXLKi CCCBPaTXOIlt
B1S1BDS; POLTCBIOBIIITED BIPBEITLS
BIFBBBICE
Yoshlda, s.
lakaaaca. t.
-- 1979
Bulletin of
BnTironaaatal
coetaalaatloa aad
toxicology 21:111-115
llcotine (8 CX)
Pyrldlna, 3-(1-aethJl-2-pTrrolldiayl|-, (S)- (9 CI)
CIO-BU-12
BR 162.23, BP <-80 C. BP 2*7 c (partial decoap) at 7«S BB Hg, 123-125 C at 17 aa Bj, TP 1 aa Ig at 61.8
(XSSOB
211
Bilk
EXPOSOBE ioom
Xahalatloa
.
tllLTTICtl
BBTBOD
GC
IDIBBI
OP CiSBS
15
SHOE
a) <20-5I2 ppb
b) 0
BSlI
a) 91 ppb
b) 0
GEIEB1L XIFOBBMXOI
a) Saokers
b) loaaaokera
Saaplu declag Oct 1973-July 197*
ven ftoa (kite, or baa, elddle-clau
doaon froa aetcopolitan laakvllla.
CoBceatratioiM la ailk ahoali aot
contraiDdicate breaet feed lag by
Bother iko aaokaa
tte iBfaot eiposoze, kevevec la not
Halted to tkat alcotiae la ailk.
Tke reaalta offer oae t artker reaaoa
for Botkera to reduce or atop
•Bokisg.
SBOKXia; Bill; IIFIITS ; BXCOTXIBt
OBoes
IBFEIEICE
- -
PergaBon. B.B.
BilBOB. O.J.
Sckaffaer, I.
1976
laericaa Joernal
of
Diaeaaes of children
1301837-839
Pkeaol. 2.2'-aatbylenabia(3,*,6-trichloro-
70-30-*
C13-B6-OL6-02
BB 406.92. BP 164-165 C
IWtYTICiL
BEtBOD
tXSSOB
212
Bilk
EIPOSOiE BOOTS
C
g
8C-EC
IDBBEB
OF C1SES
BAIGB
a) "trace" (
-------
Polybrosinated blpheayls (lo postings IB CBBBLIIB).
nssoB
213
Bilk
21*
•ilk
215
Bilk
216
Bilk, fat
EXPOSURE 1OOTE
IngeStlOB
Ingeatlon
alUTTICll
RBTBOO
6C
IORBBI
OP CUBS
5)
«2
BalGE
0.21-92.66 ppa
lot detected-1.2 ppe
lot detected-O.S ppB
25.63 pp.
4) lot
b) lot given
GEIBStl IIPOIBkTIOl
Residents of dairy turn* in
Bid-Blchigaa nko h»d beea e I posed to
PBB*. Control* (COB fang IB the sasa
geographical area.
BBOBIIB OEGkBIC CO a POO IDS: PURS;
PUB BEtaBDARTS; POOO COItlRIIaTZOI;
BLOOD) BIOICCOROLHXOI ; CHUM El;
t DOLTS; ADIPOSE T1SSDE; A 11(111
POFOIATIORS) POLTBIOB1 BATED
BIPBBIILS; BiORIIATEO BIOtOCJtIBOIS ;
BOBU tBEkS
B«»i«»
Person* IB RickigBB •zpoB«d to
coatBBiaatBd products.
lo Beat* or •aact-t«n lllasa coald
b* cl«Bcly Bttcibatcd to ssposac* to
PBB.
POlIBIOimTBD BIPBEIILS; FOOD
COITlBIBtTIOB: 1K811 MPDIMIOIS;
RICBIGtl; PIBB BBTABMBTS; BLOOD;
1DIPOSE TISSOB; BUB; BBTISI
B«*i» Of Pll»B««t«r COBtBBiBBtiOB Of
CBtti* feed ID BickigBB *sd
c«coBM(ditiOBS tor narsini Bathtrs
JAPtB; 1POLT5! IBP1IT5) SBIB
DISEiSESJ BILK; RBVIEV;
»0»BBOBIB1TBD BIPBEItLSl
POLTCfltOBIBlTZD BIPBBBILS;
BioicctiBaikHOB : PIBB IBTIIDIITS;
POOO COBTMIBHIOB; POODS; tkCtlTIOli
POPOLITIOI BIPOSOIE
-
B) lorar pBBiuaU-SI/53 bad
datectsbl* !•*•!*
b) Opp*c psnlnsol*- IB/42 bad
d«t*ct«bl« l«»ls
l«sid»ts of 2 distinct trass of
Blcbigu, sgss 1* to «5 yrf vho ga*e
birth daring tagast 1976.
BIPBEIIL COBPO01DS; BBOBXBBl B1U;
BKBIQ4B
BEPBIEICE
Baspkrsr* B.E.B.
Bsrnvr, l.S.
1975
T»c* Sabstsness in
EBflronssatd Hasltk -
II, D.D. Resphlll
(Ed.) , Proceedings ot
University at
Rissourl's 9tk Annual
Cooter*nce on Trsce
Substances In
Barlronaentil Bealtti.
Oniversltr ot alssourl.
Columbia, HO pp. S7-63
Danckel. ».J.
1975
Journal of tke laertcan
Veterinary Medical
association
167(91 :638-8«l
Billar. I.I.
Pin berg, L.
1977
Journal of Pediatrics
90(31:510-512
-
Brilliant. L.B.
ksbarg, C.T.
Isblster, J.
Buspbrey, B.
•llcox. B.
Eyster, J.
Blooser, k.B.
Price. B.
1978
Lancet 2 (809 1) : 6*3-646
Polychlorluted gaatecpkenyls (Bo postings la cflBBLXBBl.
XZSSOB
217
Bilk
UFOSOBK BOdTB
ABUTTICli
HBTBOD
OC/BS
BOBBEB
OP CaSBS
1
BiBCB
lot applicable
BEkl
0.3 ppb
CBBSBkL DPOIB4TIOB
PCB nocker
37 TC old Japaaeee
JaFll; aOOLTSt IOTOPSIBS; CBILDIEI;
Units; DISI15BS; kOIMSB TISSUE;
BLOOD; IITBS1IIBS; LITBB; BtlBi
CORPtUTIfS ITklOaTIOBS: CBLOBXBB
OBUBZC COBKWBDS; POlICBlOBIIiTBD
BUUmSt POLICBIO Bill TED
OUTBIPOITLS: MOD COBTUZBaTIOB;
RULTB UUBOS
BBP1
Kasbisoto.
Hiyata, B.
Kaaita, 1.
1981
Pood and Ci
toxicology
iBBBCB
T.
Mastics
19:335-3*0
-------
Seleniaa
77B2-«9-2
Se
ktv 78.96, HP 170-217 C, BP 685 C, VP I •• Bg at 356 C. 10 •• Bg at «29 C
TXS9DE
218.
Bilk
219
Bilk
220
Bilk
EXFOSOBI IOOTE
AlALTTICtL
HITBOD
Flaoroaatrr
6C
BOBBEI
OF CASES
2*1
13
SAI6E
0.007-0.060 ppa
a) 8-34 ng/al
b) lot given
c) lot given
d) lot given
e) lot given
f) lot given
g) lot given
M lot given
BEAI
0.018 ppa
a) 16.3 «or- «.9
ng/al
b) 11.2 *or- 17.3
ag/al
b| 15.7 «or- *.9
d| 16.3 »or- ".8
ng/al
e) !».» «or- 1.6
ng/al
f) 15.2 »or- 3.2
ng/al
g| It.l *or- 3.2
h) 15.9 »or- 3. •
ng/Bl
CFIEB1I. IIFOlaiTIOl
The nag* of «Tec>9*
fro« radoai citiu m« fco« 0.013
ppi !• UCOB, Okio. to 0.028 ppa i«
SioBX PBllC, SO. BOBt »«C« HitkiB
0.016 to 0.02* pp> S«. OBlr 3 me*
in the no4« of 0.052 to 0.060 ppl
SB.
fb» 211 salilvctB who dOBBtcd Bilk
•BBplU »«r« BOCBBl.
aOBiBBtltBtiOBBliXOd, BOBpEBgBBBt
•OMB, «kO liMd KltkiO «00 kB Of
tkaic r««p*ctl*« dtlBB fot at
on* i«»r. l*«EBg« tqm of tk« Bilk
dOBOCB' •»• 27. « jc. «Bd B*«r«g«
BBBbBTB Of d«J« DOBtpBFtBB >k«D
collected ••• 183 itj*.
BllJt: BBBIST: OBBII lilts; SB.1IXOB;
UULS; SOOIH DMOTAt OT»B{ MITMli
OBBCOIi PEJISTLTlHAl AUSOM;
axssoou; lORi; ckLiroMU; GIOICIA;
iioaiic; nzts; oauoBa: COMMDO;
•El 1011! COIIECTKOT: OBIO
••*!••
BBTIBIi BEMLS: tUCB BtBSBITS;
COPPEI; BilCMBSBi SHBIIOB;
CBBOBIDBl IBIBOII; FITOS; BLOOD
P.LISB1; BBIIBSOCIKS; BILK; LITEI;
DIITED RIBCDOBt IRIXTIOMI.
nau
•) 8 BOtkvc*. BBBplM 3l/d«j b«foc»
Bacoiag, at I. 2. Bad 3 BO paBtpartaa
b) • BOtkaci. coloBtna aaaplaa fcoa
aack braaat, I-* daya poatpartaa
c) Saaplad bafore nacalBg at 2 »k
lactation
d) Saaplad attar aacalag at 2 vk
lactatloa
•) Saaplad bafoca nacalnq at 1 BO
lactation
f) Saaplad altar aacaiag at 1 ao
lactation
g) Saaplad before nvralag at 2 ao
lactation
k) Saaplad after nacaing at 2 ao
lactation
e)-k) 5 BOtkera aaaplad 2z/daT a) aad
b). g) aad k) differed, p <0.05.
Sigalfleant poaitiTe correlation «ith
protein COBteat, r • 0.«9
tdditlonal data praeantad
Lactatlng aothara, I day-3 BO
poatpartaa, H
lUXIOIS; *00»S; IIFklTS; BIO00
SBBOB; BILIti EBTIU; SBllBIOBi DIETS;
FOODS; LtCtmoi
REFBBICE
Skearer, t.i.
Badjlaarkcoa. D'.S.
1975
irchliaa of
Ba*iroBBeatal Bealtk
3015) 1230-233
Ska*, J.C.L.
1980
Aaericaa Jograal of
Olseaaea of cklldrea
13«:7a-8i
Salth. l.a.
Picciuo, B.F.
Bllaer, J.i.
1982
iaerican joaraal of
Clinical latritlon
35:521-526
-------
Sodlua, ion {!»(!•))
173*1-25-2
la
atB 22.98977
tissor
221
•ilk
EIPOSOBE ROOTS
UaLTTICll
HETHOD
10 BBSS
or CASES
BUGE
11-20 ag/dl
•>#
flEM
I9t given
GEIEI1L IIPOBI1TIOI
loses in Blralaghaa. Bristol,
Cardiff. Edinburgh, and Mucastle
SODIOl; PLOOBIIE; IODIIEI HETaLS;
Hill: OIITED KIIODOR
BEFEREICE
Anon
1977
Lancet I (8017) :9 18
Tecbnetins. isotope of iasa 99
U133-76-7
TC
*tR 98.9062, HP about 2250 C
TISSOZ
222
flilk
BIPOSOBB BOOTE
Injection
AHlTTICaL
RBTBOD
Badioietcr
iOHBSR
OF CUES
1
B1MOE
a) 1 X 10(E»6) cp« ri.0»
ucil/t ni
b) 1.96 x 10(E»2) cpi
C2.0* x 10(B-«) UCIV* «1
a) lot
b) lot
GEIE11L IIFOIHITIOI
a) Peak 7 be after adiinlatration
b) 48 br after adaioUttation
(•ligktlT above backgroanl)
1.9 x IO(-B»IO) cp» (or 20 xCi)
iojectel. specific activity not
givea. Data available for
iateraediate-tiae poiats.
29 rr old iactating aother, 7 »k
poatpartoa.
UCNTIOli BU.K; UTILS; TBCBIBIIOB;
IkOIOISOTOPBS; OHIO
BEFEIEICE
Pittard. v.B.
Bill, K.
Fletcher. B.O.
1979
Journal of Pediatrics
9»(Q) :60S-607
Tocopberol
U06-66-2
BlaCt COHPOSITIOI OIKI01I OR OIOETEIIXIED
TISSOB
223
Bilk
EIPOSORZ BOOTE
1ULITIC4L
RBTBOD
IOHBEB
OF CASES
8
BIHCE
0.22-0.50 ag/il
RBI I
lot given
OZIBBAL IirOIUTIOl
6 aaaplea of breaet ailk
Bother* of preaatare infante
fllalllSi IEIBOBI; BIOOD PLASBA;
BILK; COHPitlllfB EV1LOATIOIS;
IIUITS; DIETS J BOTIITIOIkl
DBFICIEICIZS; IOTBITIOI1L DIMIDBBS
BBFEIEICE
Bell. E.B.
Broun, B.J.
Rilner, 1.
Sinclair, J.c.
teporskv, 1.
1979
Pediatrics
63 (6): 830-832
-------
Ocacil, 6-propyl-2-thio- (6 CI)
»('•)-PreiaidiBOB*, 2,3-dihydro-6-propyl-2-thioxo- (9 CI)
51-52-5
C7-HIO-I2-0-S
81 170.25
TISSUE
22*
Bilk
BIPOSOBB BODTE
— - -
Ingastloa
IIILTTICIL
8ETHOD
Coloriaetry
-
IOHBEB
OF CUBS
9
BMGB
O.T-0.5 ag/al
BE* I
131 given
GZIIEBlL IBrOBUTIOl
1.5 and * he MIDI. Initial value.
0.55 ag/al at 0.5 he. Don, «00 ag.
» he excretion, aetn of 0.025S of
doM. Estiaatad ftOB graph*.
Lactating, euthicold healthy voaea,
1-8 eon tha aftec dellTery, ages 21-3»
jr. 2 treated foe Craves diaeaae.
DBOOS; BIIK; BLOOD SEB0H; IICTITIOI:
DEBBABI; BBaLiB BIZtEOS
IIEFBIISICB
Kaapaaaa. J.P.
Baasca, J.fl.
JohUMD, K.
HBl««g. J.
1980
Laacct 1(81711:736-738
Valeric acid. 2-pcopyl- (8 CI)
PcntADOlc acid, 2-propjl- (9 CI)
99-66-1
C8-B16-02
HB 14*.21. BP 120-121 C at U aa Rg. 128-130 C at 20 aa Bg
TISSOE
225
Bilk
BXMSOBB BOOTH
XagcstioB
IBUITICtL
NBTBOD
GC
BOHBEB
OP CkSBS
1
BIKE
a) lot gi»«n
b) dot givea
HEm
a) 0. IB ug/al
b) 0.«6 ag/al
GBBEBtL
a) 62 hr aft«r birth, 16 he attcc
250-ag doa«
b) 130 he aft«c bieth, 3 he aftac
250-ag doa*
27-yc-olA «oaaa »lth patit aal, focal
aotoe aalxacaa, aid oocaaioaal grand
BB! flrat aaaa at 33 «k gactatloa.
lafaat d«li*Bcad at 39 «k.
OBBOOB; OB08S! DMfl TBBB1PT;
PlaCHTai PnOS( BIXJC; BBiBOll:
IIPlBISi BEOtOHOSCOUB DUIaSIS;
BLOOD! BLOOD SEBOB; IRICOnOLSMtSi
LaCUTIOB i OOBILICil COBD
BEPEBBBCB
Dickinaon, B.C.
Barlaad, B.C.
LTBB. B.It.
Salth. B.
Garbar, B.
1979
Jooraal of Padiatrlcs
9* (5): 832-835
Vanadiua
•vs. k JB ._«•*_"»
7MO-62-2
»t« 50.9*14, HP 1917 C, BP 3000 C, TP 1 aa Bg at 2290 C, 10 aa Bg at 2570 C
TISSOE
226
Bilk
BXPOSOBB BOOTS
iBhalatioa
Ingaatlon
1I1LTTIC1L
RETHOD
M
BOHBER
OP C1SES
5
BMOE
0.5-1.2 ng/9 dry «t
BBil
Ot given
OBBBBIL nrOBBlTIOB
Total body pool is aatiaatw) at 106
ag. baaad oa orgaa weight of tha ICBP
Bafartaoa Baa (10 kg boaa at 3 ag/g,
5 kg blood at < oc » 0.2. 28 kg
aoacla at 0.5. 15 kg fat at 0.7, 1.8
kg lirar at 10, 1.* kg braia at 0.7,
1 kg loag at 30, 0.3 kidaay at 5).
Taaadlaa, gaaccallr conaidarad
auaatial foe gcovth in aaaaala, ia
aaaallr Ion in foodatafta. Tha ion
l«?el ia Bilk, agga, and SOB* othar
tiaaoaa iaply that its c*gair*a*at
foe growth la aiaiaal aad probably
laaa than pr*»ioaaly aatiaatad.
BETiLS; TllaOIOBi 0 Bills PBCESl BalB;
BOIISl TBBTBj (IDUISl LITBll 8B*II|
tanoiD auiDSi BUB.TI ADIPOSE
TISSOli BOSCISS; 3PLEEI) PlICBEiSl
LOI8S) BLOOD
BirniicB
Byrna, *.B.
Kocta, L.
1978
Sclanca of th* Total
EaTicoaaaat 10: 17-30
-------
line
7MO-66-6
Zn
AtW 65.38, It I HI9.5 c, BP 908 C, It I •• Hg at 487 C, 10 •• Hg at 590 C
Tissue
227
811k
226
Rllk
-
229
Bilk
230
•Ilk
EIPOSOBE BOBTE
* *
Ingestlon
ANALYTICAL
RETBOD
AAS
115
US
.
IOHBBB
or cases
so
•
a) 28
b| 39
e| 23
d| 13
•) 28
f| 30
a) 76
b| 77
c| 23
d| 79
•t 25
BARGE
0. U-3.9S ug/*l
a) lot given
b) lot given
c) Hot given
4| lot given
•) Mot given
fj Not given
•) lot given
b) lot given
c) lot given
d) lot given
e| lot given
HBAI
1.62 uj/sl
a| 1.60 t 01 - 0.23
ug/Bl
b) 1.05 » or - 0.1S
ng/Bl
e) 0.75 ' oc - 0.11
ug/al
1) 0.63 » or - 0.09
ug/Bl
e) 0.69 » or - 0.18
ug/al
f) 0.60 » oc - 0.19
ng/sl
a) 5.32 ug/el
b) 2.00 ug/Bl
c) 1.16 ug/al
41 2.0 ug/Bl
e) 2.5 ng/al
GEIEBAL IIFOBRATIOI
Since lost obaarve.1 variances vere
accounted foe by variation* asong
aethers, a representative estinate
could probably be obtained Iron
analrai* ot one sacple.
Saaplas free Pennarlvanla Bothers.
«2 sabjecti vere between the ages of
20 and 30, while 8 vore over 30.
All subjects had healthy, fall-turn
infants.
COPPEB; IROI; ZIIC: RETiLS; IIIBULS:
BBTtBOLlSH; tlCTATIOI; DIETS; 8II.lt;
IBIBOBI; PeilSTLValll
a| 1-3 BO lactation
b) •-« so lactation
c) 7-9 so lactation
d) 10-12 so lactation
e) 13-18 so lactation
f) 19-31 BO lactation
Ihite «OB«n, !9-*2 re *ge. 22
priaiparae and 16 saltlparae.
BtOOD SEE OH; HI IK; HUB; URALS;
LlCTaTIOl; CUCIOH; H40IESIOH;
BalfiilESE; IBOl; coPPBi; ZIIC
a) Colostras, high and low incose
groups
b) after lactation 1-3 souths, high
and low iacose groups
e) iftec lactation > or - 13 aontka.
high and lov ioeose groups
d) Iftec lactation 1-3 aoaths, lov
incoae group
e) tftar lactation 1-3 nonths. high
incoae groap
Significant difference betveen Incase
groups at 1-3 souths but not at »-6
souths. Uditional data available.
loaen fCOB urban and cural India.
SETILS; TlaCE ELEHEITS; COPPEB!
HACIBSIDIl ZIIC; UIK; COHP1UTIVE
BVlLOmOIS; OBBAI ABBAS; BOBAL
AiEAS; IIDIA
Beviev. Profile of healthy subjects.
Baaelin* data for detecalBing changes
in nutritional status fros industrial
food poisoning technignes.
IE! UUllDl ADOITS; FETOS; IlfAITS;
81OOO SBIDBi HAIB; K10IBIS; IITBI)
•ILK: lETXBt: DIETS; POODS; SOILS;
IEOBIATIOB; C10HIOBJ COPPSI:
BliaAIESE) BETALS; TBACE ELIHBITS;
rue
(EFE&EILE
plcciano, n.r.
Guthrlc, H.A.
1976
Ascrlcan Journal of
Clinical Nutrition
29:2*2-25*
Vaughan, L.A.
Reber, c.H.
Keaberling, s.R.
1979
aaerican Journal at
Clinical lutrition
32:2301-2306
Bajalakshsl, K.
Srlkantia, S.6.
1980
Aaarlcan Journal of
clinical lutrition
33:661-669
Gathrie, e.E.
lobiason, R.P.
1978
lev Zealaad Radical
Journal 87(603) :3-8
-------
,l,3.4-Betheno-IH-crclobiita(cd) peatalene, I, U.2.2,3>3t,4,5,5.5a.Sb,6-dodecachlocooctihrdi:o-
2385-85-5
CIO-C112
Bl 5*5.6, He »85 c. fP 6X10 (B-6) •• Bg «t 50 C
TISSOB
231
Hilk, fat
EIMSORB BODtB
alUITXCIL
IETBOO
BPLC
as
GC-BC
.
•OHBBI
OF USES
It
UIGE
-
a) 6.4-21.5 ag/g fat
b) 2.3-11. 1 ng/g fat
BBAI
a) lot given
b) lot glvea
GBIEBal XIFOIItTXOI
a) Baas *pectroeetrlc aethod (HS)
b) Ot* chroaatographic aethod (OC|
Poor agreeeant betneea BS and GC
reaalta. Data fcoa GC are
qaeatioBBble. airex la 3 of 14
staples aaalyzed.
1* hneaa ailk staples (5 froa
Ontario, 2 froa BastarB, 3 froa
Central aad 4 fcoa the Vest en
region)
BI«! F»TSl PESTICIDES; OLTIIVIOLET
BaDXlTXOI; CBLOBXMTED HTDBOCaBBOIS;
ClIlDig BIE1SI
IEFCSEICE
Baa. J.
oavies, D.J.
Bile*. «.
1978
Bulletin of
Environaeatal
Contaaioation and
Toxicology 19:564-570
,«:S,8-Diaethanon>phtbaleoa, 1,2.3,*, 10. 10-hexa:hloro- 1.4. 4a,5,B.8a-hexahydro-. eado.exo- (8 CI)
.*s5,8-DlaetauOBBpathalono. 1.2.3.4.10, I0-hoxachloro-1,4,4a,5,8,8a-hoxahydro-, (!alpha,*alpha.*abota,5&lpba,8&lpha,8abata)- (9 CX)
309-00-2
CI2-H8-C16
ai 365.93, BP 10* C, TP 6X10 (E-6) aa Bg at 25 C
IISSOE
232
BiU
233
•ilk
23*
•ilk
EXP030BE IOOTB
lagaatioa
IMLTTICiI.
BETBOD
GC
tic
CC
6C-BC
ID BEER
OF CISES
1
a| 21
b) 2*
c| *5
d) «5
IS*
BalOB
lot applicable
a) lot datactad
b) 0-0.090 ppa
c| 0-0.090 ppa
d) lot given
a) 0-0.74 agAg (at
b) lot given
c) lot gives
' ' (IBXt
HBII
21.8 ppb
a) lot detected
b) 0.00* ppn
c) 0.002 ppa
d) 0.00004 ppa
a) 0.011 »oc- 0.068
eg/kg lat
b) 0.03 »oc- 0.03
ag/kg fat
c) 0.05 «oc- 0.10
Bg/kg fat
PiOB)
8BIIUL nrOIBIHOI
Bilk Miplea, hoapitala in arbaa
Oslo. 4 aaaples froa Balliagdal, a
taller IB aaataern lomai. lo
ocoapatioaal eipoaare.
•UK; XISBcncXDBS; UCTMXOI;
CBLOlXlaTIO BIDROCiBBOISl CUOIIIE
OBOalXC COBPOOIDS; PB3TICXBIS) BOBIaT
a) Baral aothera. fat b«ai«
b) Orbaa Bother*, fat btaU
c) all aotkera, fat baaie
d) all Bother*, "hole Bilk baaie
Data for aa* of all peatic idea and
coapariaooa «ith valaea of other
investigates* given
Inning Bother* froa Cordoba region,
Spaia
SPilli JLDOLTS; BlUtl CBLOIXIB OBOtlXC
COBPONOSl MSTZCXDBS) iSBXCOLtOBBi
BOBiL ilBaSi OBB1I aBSaS
a) 0.001 »or- 0.003 ig/kg naola Bilk,
all aaaple*
b) lural cealdanta, 19 aaaplea
c) Orban reaidenta, SI aaaplea
3-6 dare poatpactna. 31 exceeded
codex tliBBBtariB* Coaaiaaion liaita.
lo correlation vith age or place of
raaldence.
18-38 ir old*. Canada
UDBXI; C.IADlj MB I IZLC CBLOBZII
OiailXC COBPOOIOS; DOB; DOT)
BBIaCnOBOCIClOBIUBB: LIIP1IE;
POUCBLOBXI1TBO BXPBBIILSl POPOLMIOI
BIMSOIB; BOBiL »«E1S; SBOKIIOl OIB1I
aBlaS
BBFBIBICB
Bakkea. l.r.
Seip, H.
1976
leta Paediatrica
Scaaaiaavica 65:535-539
Poxo Lot*. B.
Berrera aartaache, I.
Polo Tillar, L.B.
Lopez-Glaanaz, I.
Jodctl Tlllacejo, a.
Igle*ia* perex. J.
1979
levieta Mpaaola de
Pediatria
35(206):93-IIO
Dillon. J.C.
Hartia, G.B.
O'Brien. fl.T.
1981
Food and Coeaetlce
Toxicology 19:437-442
-------
1.«j5,8-Dla«thaDOnapbtbal«na, 1,2. 3,». 10, 10-b«i«c»loro-1,«.»a, 5. 8,8«-hai«bTa 89 at 20 C
TISSUE
236
Hauarf
9! And
237
Ulk
238
•ilk
EXPOS DIE BOOT!
tlUITICU
BBTBOD
CC
SC-EC
CC-BC
CC
GC-BC
IOHBEI
OF CtSBS
•) 5
b) 9
CI 9
57
6
MICE
a) O.I6-0.47 ppi
b) 0-2.67 ppa
C) 0-1.25 pp»
trac«-0.05 ppa
•| lot detcctable-0.25
ppa
b) lot detectabla-0.012
ppa
BEkl
a) 0.2891 ppa
b) 0.9056 ppa
c) O.»590 ppa
0.012 ppa
a) 0.05 ppa
b) 0.003 pp«
P&CEI
GEIEBAL IirOBBATIOI
a) Control
b) aalignant
c) Braaat tlaaaa adjacent to
aallgnancr
Baligoant tiaaaa, adjacent to
apparently norul glandular and
adlpoaa tlaana of nine vonen nitk
adeaocarcinoaa of the breast.
obtained froa the A.C. Caaargo
Boapital in Sao Paalo. Baaaary gland
and adjacent adipoae tiaaaa froa 5
healthy voaen »ho died accidentally
aaed for coatrola.
BBBAST; BABBABT GLABDS; IMPLASBSi
ADIPOSE TISSBB; CUCIIOBAS;
PESTICIDES; LIPIDSt CBLOBIIATED
BtDBOCABJOBS; CBLOBXBB OB0.ABXC
COBPOOIDS: BXOACCaaOLATIOE; BIPBBIIL
CORP001DS; DZBUBXB; POLTCBLOBIBATED
BIPBEITLS: DDT; DOB:
BEXACBLOBOCyCLOBEIAlE: ODD;
BBPTACBLOB EPOXIDE
BeaidM levala nece balov laatrraaat
sensitivity and eoeld not be
coaf icaed .
Saaplaa froa 17 Begroea and no
Caacaalana in koapltala ia Arkaaaa*
and Blaaiaaippl.
PESTICIDES; PESTICIDE BBSIDOES; BILB;
BIOACCOBOLATIOI: lOMLATIOl EZPOSSBE;
BABBABT 6LAIDS; LACTATIOI; PLACEBTA;
ABUBSAS; BZSSISSIPPI
a) Taluaa foe Bilk fat
b) Talaaa for ikola ailk
Saaplea f COB resident* of Baeaii
collected froa I9*«-I973
PESTICIDES; BAIAII; FBTBS; FETAL
BEBBBABES; BUB; BTEBDS; BLOOD SBBOB;
DM: DDIt DIBLDBIB
BEFEREBCE
lasaeraann, R.
Bognaira, D.P.
Toaatia, L.
airra, A. P.
Shibata. B.
aria. G.
Cacoa, s.
Baaaeraana, D.
1976
Bulletin of
BnTiroaaental
contaainatlon aad
Toxlcolog y
I5(«) : (78-48*
Straaaaaa, S.C.
BMx, F.B.
1977
peatlcldea Boaitoring
Joarnal 10(41:130-133
Kleaaer, B.I.
Budy, A. a.
TakaJiaahl, I.
•aley. T.J.
1977
Cllalcal Toxicology
11f1)s71-82
-------
l.aiS.S-DiBBtbaBOBapatBalan*. 1.2.1.*, 10,10-BeiacBloco-6~.7-apoxy-1,«,aa,5,6,7,8.Ba-octahySro-, •ada.mta- (8 CI)
2.7t3,6-DiBathaBOBaphtb(2,3-b) oxicana, 3,a,5,6.9,9-haxacU.aco* la,2,2a, 3.6,6a,7,7a-octaBydro-, (laalpha,2bata,2aalpha.3bata,6b«ta,6aalpaa,7Bata.7aalpBa)- (9 CI)
60-57-1
CI2-HS-C16-0
B» 380.93, BP 176-177 C. »P 7.78I10(E-7) BB Hg at 20 C
(COITIIOSD)
TISSDE
239
Hilk
2*0
Hilk
2«1
•ilk
2*2
Bilk
2*3
aiik
BXFOSDIE iOUTB
aUlTXICal,
BETBOO
IL:
GC
GC
OC-BC
oc
TIC
IDHBM
or CUBS
a) 59
b) IS
c| 97
2
•1 5
b) 5
57
6 of 50
UICE
•) 0.9-2.6 og/kq
b) 0.8-1.8 ag/kq
C) 0.1-1.3 ug/k*
0.10-0.13 09
•) lot giT«n
b) lot gi»an
Tcac«-0.05 ppa
0.3-3.6 ppb
BBl*
«) 1.* ag/kq
b) 1. 1 ag/kg
C) 0.7 ag/kq
0.12 04
•| 1 gaaaa/diy
b) ui«d foe dlf («C*Bt
fMdlags. T«la» «r« daily total.
MiplM CEOB doBora at *aciou ti«««
of bccaat twdiog and at dittecmt
tlMS of ta« day.
BIU: PESTICIDES: PB5TICIOB USIDOES;
POUCHLOIIIaTED BIPBEII1S:
BIO1CCVBOUTIOI i BKaCBLOlOBElXIIB;
ODTl BBUCEtOIOCIdOBEItlE;
amkcnoB EPOIIDI: oitcBLoiDaii;
BOIaCBMR: DOB; OIILOBII
a) B»a«t-f««dl»g aothcc* »ith ou
ckild
b) Bna«t-f*adlag lotkaca nita tuias
Data for 197«
two gcoup* of bnast-foodiag aothaca,
o>* gronp fa«ding on* iafaat aad ta«
otter gcoap f*adlag t«iu.
pmxcuis: CBLOIIIE oiemc
COBPOOIOSi CBLOIIUTEO BIPROCalBOIS:
BtBUT: IBFaBTS; POODS
Lactatlag WOMB ia a«l*ct«d aria* of
ickaacaa and BluUalppi.
BIU; PESTICIDES; IDIPOSE TISSDEt
BtTaBOLITES; CUOIIIE OlOaBXC
COBPOOBDSl CBLOBXMHD BTDBOCaUOBS;
LaCIiTIOlI OIICBLOfcDUE; pDt;
lOIlCBLOtl BKPTICBLOB IPOIIDEl
DIELDBI1; BEUCBIOtOCICLOBBIllE; DDE;
alUBStS; BIS3ISSIPPI
Bilk aaapl**, hoapltals ia irbaa
Oalo. a aaaplca fcoa Balliagdal, a
*all«T IB ao»th«rn lornaf. Bo
occupational •xpoaar*.
Bill; IBSBCTICIOES; UCtatlOl;
CB101IBMBD BtDtOCAlBOMl CBIOU1B
OBOAHC COBP001DS: PESTICIOES; Mil IT
EBFESEICB
iMtOO, C.
loraa, K.
1978
a«blo 7(2) :62-«a
Bo», J.
Datics. D.J.
1978
Ch*ao>ph«r*
7 19|:699-706
Idaaotic. V.I.
Sokic. B.
SailjaBakl, a-J
1978
Bollatla of
B>Ticoaa«atal
CoataalaatioB aad
Toxicology 20s 280-285
Ruts. P.I.
Strauaaa, S.c.
lob*, l.B.
1976
XBtaraatioaal fockaaop
OB Biological SpaclaBB
OollKtioB. apcll,
1976, taxvaboarg
Bakkaa, a.f.
s«lp. a.
1976
let a paadlatciea
ScaadiBBTlca 65:535-539
-------
I.«s5,8-Dlnetkanoupktkalone, 1,2,3.*, 10, IO-hexackloro-6,7-opoxy-1,a,aa,5,6.7.e,8a-octakydro-. eud3,e»- (8 CI)
2,7«3,6-Dlnetbanonapfctfc (2. 3-b| oxirane. 3>a,5.6.9.9-ko»cliloro-1a,2.2a,3.6,6a,7,7a-octakydro-, (1aalpka,2beta,2aalpha,3beta.6beta.6aalpha.7beta,7aalpka) - (9 CI)
C12-B8-C16-O
H« 380.93, HP 176-177 c, VP 7.78IIO(E-7) u 89 at 20 C
(COITIIOED)
TISSUE
2»*
Bilk
2«5
Bilk
2*6
•ilk
2«7
•ilk
EXP0501E BOOTS
IMLYTICiL
HBiaoo
GC
GC
GC/BS
,
GC
BDHBEB
or CASES
2 of SI
a) 20
b| 12
el «0
d) 38
•1 19
l\ 20
«l 19
•) 10
b) 25
e| 3S
d) 10
•1 20
(I lot
given
a) 27
b) 10
c) 10
d) «0
BklGE
lot given
a) lot given
b) lot given
c) lot given
d) lot given
•) lot given
f) lot given
g) lot given
.
a) lot given
b) lot given
c) lot given
4) lot given
•) lot given
f) 1-6 ng/g
.
a) 0-0.010 pp»
b) lot given
c) lot given
d| 0. 001-0. 015 ppn
~~ — — — — — C»B*T
IIEll
0.01V ppn
a) 0. 1 ppn. Cat basis
b) 0.15 ppn, fat
basil
c) 0. 17 ppn, fat
basl*
d| 0. 18 ppa, fat
basis
e) 0.20 ppn, fat
basis
f) 0. 1 ppn, f nt basis
g) 0. 1» ppn, fat
basis
a) 2 ng/g
b) 1 ng/g
c) 2/ ng/g
d) 1 ng/g
e) 2 ng/g
f) 2 ng/g
a) 0.002 ppn
b) 0.005 ppn
c) 0.070 ppn
d) 0.005 ppn
PJkCB)
GEIEBtl IiroBIUTIOl
landos sub-facts of greater St. Louis,
HO, netcopoliton area.
PESTICIDES: CHLORIIE 0161IIC
CORPODIDSi DDT; DOE; OIELORII;
HBXACBLOIOCTCLOBIUIE: BBPTICBLOI
BPOIIOBi BILIti BISSOUBI; COSPlRiTHf
ETA1D1TIOIS
a) 1971
b) 1972
c) 1973
d) I97«
e) 1975
f) 1976
9) "977
Estlnated fron graph
Botkers In Osaka Prefectnre
BIPBEIIt COHTOOIDS; CHLOBIIE OiOillC
COBFOOIOS; DDE; 001; DIELOIIli
BBXaCBtOBOCXdOBEIllEs J1P»I| BI1C:
FOIICBLOIIIITED BlfBEIILS
a) Eastern canndn
b) Qaebec
c) Ontario
d) Ceatrnl Canada
e) fester n Canada
f) latlonal average, sanples above I
•9/9
latlonal Sszvev, 1975
BIPBBIH COBPOOIDS! CMIOk! CBtOBIIB
OIG1IIC COBPOOIDS: DDE; DOT;
DIELD1II: BEPTtCBLOR EPOXIDE;
BBXaCUOIOBBISIIB ;
BBUCBlOIOCICLOBnalBj Sill]
lOlaCHlOt: OHCBLOI01I8; PBSTICIDIS;
POIICBLOIIIITED BIPBEITtS)
POLTCBtOIIIitEO TMPBBITLS
a) Cotton, corn, and aesaae-gconing
are*
b) Banana area
c) Cotton area
d) Coffee-gronlng area, Bl Salvador
a)-o) IB Gnatenala. Blgkest use of
pesticides oa cotton.
Botkera fron lon-incoae Canilles in
Gnntesala and El Salvador, anas
chcsen to represent different degree*
of use of pelticides.
Ovecose of pesticides a particular
problen in tropical countries.
Prevalence of sains trltion say
contribute to kealtk effects.
iGSXCOltOBE; CHIOMIE OIGAIIC
COBPOOIDS; CBOP OOSTXBG; ODt;
DXELDBXB; Bl SlLTlDOl; fOOD
conuniTioi: couBBaui
BBXACBLOBOCICLOBEUIE; BBFTaCBLOB
IPOXXDB; IISBCTICIDS3: BII.IS
•OtUnOBlL DBFXCXBICXBSi PBSTICIDBS;
PESTICIDE BB5XDOIS
BErEOEIICE
Jonsson, V.
LlU. G.J.K.
trnbrnster, J.
I«tt«lhut, L.I.
Dracker. 8.
1977
tieclcdn Journal of
Clinical latrltloa
30:1106-1109
takusklji, T.
•atanabu, I.
Kanabara, K.
Yoskida. S.
Bori, S.
rnkoskiaa, S.
Kashlnoto, T.
Rorasa, K.
Knnita, 1.
1979
Irckives of
Environ aental
Contaslaatlon and
Toxicology 8:59-66
Res. J.
Davies, D.J.
1979
Bulletin of
Environmental
Contamination and
Toxicology 21:381-387
de Canpos, B.
Olscyna-Barcys, i.S.
1979
ircklves of
Environmental
Coatanination and
Toxicology 8:«3-sa
-------
1,415,8-DiBathaBoaaphtkalaaa. 1,2.3,4. 10, IO-h«xaakloro-6,7-apoxr-l,*,«a,5,6.7,8.8a-oct«hylro-. sada.aso- (8 CI|
2,7t3,6-DiaathaBOaaphth(2,3-b)oxicana, 3,*.5,6,9,9-keiachloro-la.2,2a,3,6.6a,7,7a-octahTdro-. (laalpka,2bata,2aalpha.3bata,6bata,6aalpha.7bata,7aalpka)- (9
60-57-1
CI2-B8-C16-0
Bf 380.93, HP 176-177 C. »P 7.78XIOfB-7) » Hg at 20 C
(COmiOED)
TISSUE
2*8
Bilk
249
•Ilk
250
Bilk
251
Bilk
252
Bilk
EXMS0BB IOSIB
lagastioa
ABAtrtXCAL
HETROD
OC
6C
EOBBEB
OF CASSS
•) 21
bl 2«
c) »S
d| IS
1136
a) «8
b) 3«
el 19
l,*36
saapla*
RAIGE
a) 0-0.384 ppa
b) 0-0.112 ppa
c) 0-0.381 ppa
d) lot gliaa
97.9-2*2.3 ppb
, ,
a) <0. 01-0.25 ppa
b) <0. 01-0. 17 ppa
c) <0. 01 -0.08 ppa
a) lot glfen
b) lot gl»ea
mi
a) 0.031 ppa
b) 0.010 ppa
c) 0.020 ppa
d) O.OOOS ppa
16*. 2 * or - «36.2
PPb
a) 0.09 ppa
b) 0.0* ppa
c) 0.0* ppa
a) 97.9 ppb
b) 2*2.3 ppb
(IEIT P«BB|
GBBEBAL XBFOBHATIOB
a) Baral aothera, {at baaia
b) ocbaa aotktrs, fat basic
c) All aota«rs, fat basis
d) all aotkara. ahola •ilk bails
Data foe aoa of all pasticidas aad
cospadsoas Hitk ralaaa of otkac
gitaa
Inralag aotbacs (roa Cordoba ragion,
Spaia
SPMBi iDDLIS; BILK; CBLOBIBB OJGAIIC
COBFODIDS; PBSTICIOCS; IBIICOlTqiE;
cotu ABBAS: OBBIB ABBAS
OB fat adjoatad basis
Baaga of aaans foe all oaogcapklc
ragioaa
BaisiBg aotfcara. n.s.A.
DBZtBD STUBS: ADULTS; BILK;
COBPABATITB BTALOAIIOIS; CBLOBIBB
OBOABXC COBPOOIDS; DIBLDUB;
LACTATXOB
a) 1969-70
b) 1971-72
e) 1973-7*
Saaplia.g pacioda
Laval of aipoaara aakaoia
Oatacio raaidaata, BMB ago 2*-28 jt
IBDOSTBIAL CBBBICALS: CABADAi A6B;
AOTOPSJBS; ABXPOSS TISSUE; BUB.;
CBLOBIBB OBflABIC COBMOBDS;
CBLOBOBCBSBBBS; DDT; DIBLDBIB;
BBXACBLOBOBBBtBBB; PESTICIDES;
fOIICBLOlIBATBO BXPBBBTLS; PESTICIDE
1BSIDOBS; POPOLATIOB BMOSOBB
la*ia«. Data iadicata a dacliaa ia
naidna larala la aBTiroaaaatal
Bobatntaa aiaca tka aid-1960s, bat
BO coccaapoBdiag daclina la kuaaa
Uasa* !•¥•!•.
Basidaats of tka D.S.. Caaada. Daltad
KlagdoB. Tk* Batharlands, 1963-1976
CABAOAl BBtBBBLABDS; OIITED KXBaoOB;
01ITED STATES; ADIPOSE TXSSOB; BILK;
1ETISI; PESTICIDES; AGBICOLTOBB; AIB
tOLLOTIOB) BIOACCOBOLATIOB; DBIBUBG
HATBB; FOOD COBTABXBATIOI; PESTICIDE
BBSIDOBS; POPOLATIOB BXPOSOBB; VATBR
POLLOTXOB
a) Bortkaaat
b) Soatkaaat. kigkaat !•*•! 12.300
ppb
tan la X.7SO ppb found ia Soatkaaat,
Berth, South, aad Bidvast
OBITBD STATES; BILK; DISLDBIBl
BBPTACBLOB BPOXIDBl OXTCBLOBDABB;
PESTICIOt BBSIDOBS
BBFEBBBCB
foco Loca. B.
Bacrera Bactaacha, ».
Polo Tillac. L.B.
Lopez-Giaaaax, B.
Jodral Tillacajo, n.
Iglasias Par«z, J.
1979
Baviata Bspaaola da
Padlatria
3S(206):93-IIO
Safaga, E.P.
Baafa, T.J.
fassari, J.D.
Baaalar, B.I.
Applakaas, F. n.
Coas, B.A.
Focd. S.A.
1981
Aaacicaa Joacaal of
Bpidaaiologr
133(«):*13-«22
Roldriaat, B.T.B.
Bcaoa, B.B.
Frank, B.
Stopp*. O.J.
Saout, B.S.
Hciada, J.B.
1977
CaaadiaB Journal of
Public Bvaltb 68:7«-80
AekacBBB. L.
1980
Paaticidaa BoBltoclag
Joucaal 1«(2|:6«-«9
Aaoa
197 7a
Postidda S Toiic
Ckaaical Bans
5 (8): 10-11
-------
l,l:S,8-Dlaathanonaphthalene, 1.2, 3,», 10, 10-hecachloro-6.7-epoxy-1,*,«a,5,6,7,e.8a-octahydro-. end3,a»- (3 CI)
2,7i3.6-Dlaethanoaaphth(2.3-b)oxiraoe. 3.*. 5.6,9,9-hoxachloro-la,2.2a,3.6,6a.7.7a-octahydro-, (laalpha,2b*ta,2aalpha.3beta,6beta.6aalpha,7beta.7aalplia) - (9 cil
60-57-1
C12-B8-C16-0
N 380.93, BP 176-177 c. 11 7.78X10(1-7) » Bg at 20 C
TXSSOB
253
Rilk
25*
Bilk; fat
255
Bilk, fat
256
Bilk, fat
EXPOSURE 10UTE
AIALIT1CAL
BBTHOD
GC
GC-EC
GC-BC
GC-EC
IOHBBB
or CASES
50
a) S3
b) 33
a) 3*
b) 6
BARGE
0-95 ppb
a) Not detectable-*. 66
ppa
b) lot deteetable-O.OB 1
ppe
a) 0.0*-0.62 ppa
b) 0.03-0.17 ppa
a) lot given
b) lot given
c) lot given
d) lot given
e) lot given
CHIT
HEll
«2 ppb
a) 0.180 pp«
b) 0.025 ppa
a) 0. 15 ppa
b) 0. 120 ppa
a) 0.086 » or - 0.06
ppa
b) 0.095 » oc - 0.07
ppa
e) 0.050 » or - 0.0«
ppa
d) 0.062 » oc - 0.02
ppa
e) 0.052 » or - 0.02
ppa
P»OE)
Eitcacted liplds, Jan 1979 to P«b
1980, 3-«6 days postpartaa. lo
significant corn la t Ion tilth
residence, age, veight, nuabec ol
children previously aaraed, household
aae of non-persistent pesticides, or
occupation of spouse. Higher, but
nonsignificant levels in woaen vitb
higher freguency of aeat conniption,
and in those in bones vita pest
control treataent.
Bealthy 18-37 yr old Bavallaas
AOOLTS; ICE; BAIAIXi BILK;
CBLOBXIATBD BIOIOClRBOISj DOE; BOT;
DIEIDBII; BEXACBLOBOCICLOBEXABE;
BEPTACBLOB EPOXIDEj
BBXACBLOBOBBItllB; LIIOAIE;
IOIACBLOB; OXICBL0101IE; PESTICIDES:
PO KC BLOB I BIT ED BIPBBITLS; DXBTS;
LaCTiTIOl; PESTICIDE 1ESIOOES;
POPOLMXOI SXPOSOIE
a) 1966-1970 etady
b) 1977-1978 study
1966-70 patients (University of
Alberta Boapital), 2-10 days
postpartua. 1977-76 patieats (pablic
health offices of Albertal , 17-309
days poatpartoa. lesidencea, Edaoaton
OE Alberta.
BlUt PBSIZCXOES;
BBXACBlOlOCICtOBUAlEi ODD; DOB; DDT:
DIElOtill BBKACBMB EPOIIDI;
BBUCBlOBOBBISBIBi CAIADA;
ICnCBMIIBaTBP BIfBBBnS;
COBPAIATIVB ITALOATIOIS
at Bigh pesticide usage area
b) Lo» pesticide usage area
BOMB living in SUrkvllle.
BisslsslpFl (Low pesticide usage) and
Delta area (high pesticide usage).
Saaplea in 1973-1975.
BILK? PESTICIDES) DDE) ODD: DDT;
BBXICBIABOCTCtOBnAIBl BEPtACBLOB
EPOXIOBi OXTCBL01DAIE; OIILDUI;
BXSSISSUPIl COBPASATIVE BTIIBATIOIS;
BBASOBBBBBT BBTBODS
100-1*1 lactatlag iioaan, 2 aoaths
after delivery. Besideats of Osaka
Prefecture, Japan, varied diets and
environmental conditions.
PBSTICIDBS; DIBLDBIB; OBBAIIC
CBUBXBB COBPOOIDS; JAPAH AOOLTSi
LACTATIOl; BUK; BIOACCOBDLAHOU
POUCBLOBXBUBD BWBMTW
BEfEIEICE
Takakasbl, u.
Saldin, D.
Takel, G.
long, L.
1981
Bulletin ol
Enviionaantal
Contaaination and
Toxicology 27:506-511
Currie, a.A.
Kadis, T.I.
Breitkreitz, I.E.
Caaaiaghaa, O.B.
Brans, G.I.
1979
Pesticides Bonitorlng
Journal 13(2):52-55
Barnett, B.I.
0
-------
l,*:S,a-DiMtaBnouphtBBl«B*, I.2,3.«, 10. IO-kua=klaro-6,7-ipoxr-l.*.«a.S,6.7.8.ea-octahriEO-. a«do,«xo- (8 CI)
2.7:3.6-DiMtha.noiaphth(2,3-b)oxicBB«. 3,«.S,6,9.9-B«xachlOEO-lB,2,2B.3.6,6a.7.7a-octah7dro-, (laalpha,2b«ta,2aalpha.3b«ta,6b«ta,6aalpha,7b«ta,7aalpka) - (9
C12-B8-C16-0
n 3B0.93. HP 176-177 C. »P 7.78110(8-7) mm Bg at 20 C
(COETXBOBD)
TISSUE
257
Bilk.
MBOla
258
Bilk,
vkola
259
Bilk.
•hole
BXPOSOEB ROOTS
IMLYTICJl
BBTBOD
tic
aC/BS
OC-BC
GC-IC
-
OC-EC
IONBER
OF CUBS
-
57
155
22
UIOE
TcBca-o.05 ppB
0.005-0.021 ppB
0.003-0.011 ppi
'BMi
<0.01 ppB
I3t giVVB
0.00« ppa
GBEERAL iiroifltTiOB
-
2B.1t pail tin aanplw
Saipla* tram lactBtiag HOBS* la
•«l«ct«d «c«u of Ickusu «nd
BlniMlppi.
PESTICIDES; ADIPOSE TISSDE: BILK!
OBIBBi BIOlCCOBOttTIOl; BIPBBBIL
COBPOOIOS; CBLOBIIJITEO BTOBOCABBOBS:
MBIBS1S; IISSISSIPPI
»art«9«M VOMB. OicIicU d«t«ct«4
IB 11 o>u. SBiplM tak«B in 1972.
PESTICIDES; DOT; DDE; DISLDUI; BIJ.lt;
POMDOU
Surer. »««t«rn lastrBliB, 1970-1971
22 aiming Botkws. «t «6-66 kg,
li*iag vlthiB B 30 mi CBUu at
P*ctk, iMtcn JlutrBliB
BTlt; •BSTXCZOIS; lOSTBkLIi: DOT;
DOB; OIBtOBIB: BBItCBLOlOBEItllE
BBrBBEBCB
Intl. F.B.
StCBMBBB. S.C.
lobs. t.B.
1977
PMticil* BBBBg«HBt
BBd iBMCticid*
B«*!BUBC«. ie«d«Bic
tern**, lac.. B«v lark.
SBB FrBBciseo, Loadoa,
(pp. 523-539)
Brae*. I.
F«rB«Bd«», t.a.s.s.
BoarBo. B.C.
197*
P«»ticld*i BoBitoriag
JaarBBl B(3|:Ue-15«
_
stBc«r. c.i.
ThOBB*. B.I.
1975
PBStlcidBB BOBltOCiBg
JoaCBBl 9 (2) : 6«-(C
,7-BBtBBBO-1B-lBd»B«. 1.2,l.».5,6.7.8.8-BOBBCBl»r«»-2.3.3B,».7.7B-h«BfcldrO-, (UlpllB.2b«tB.3BlphB.3BBlphB.«lMtB.7b«tB»«UlpkB)-
f7«S-80-5
10-B5-C19
TISSOE
260
Bilk
261
Bilk
BIMSOBB BOOTS
1B1LTTIC1L
BBTBOD
6C
BDBBBB
OF CaSBS
2
57
BkBOE
0.08-0.16 ag
TtBca-0.01 ppa
(BBM
BSkB
0. 12 ng
<0.01 ppa
P10B)
6EIBI1L nrOBBMZOB
iBOBBtl TBTiBd fOC UtfUVBt
(••dings. TBlB«B Bra daily total.
SBBPI** frOB dOBOCB Bt TBCiOOB U.B*»
at bcwBt fMdiag BBd Bt dUteruk
tiBU of tk« day.
BILK) MStXCIDBSi PESTICIDE USIDOIS;
POLTCBLOBIIITED BIPBHILS;
BI01CCOBBLATIOB; BBULCBLOBOBEIItBB;
DDTj lUaCBLOIOCtCLOBEIAIS;
BBRKBUB MOZZDSl OIICB10ID»1B|
BOBkCaiOli DDE; OXBUBIB
tactatiag VOB*B in B*l«ct«d ac«a« of
irkaasa* and BUaUalppi.
BILIl PESTICIDES; tDIPOSE TISSDE;
BBIiBOlXTBS; CBLOBIBB OBB1BIC
coarooBDSi CBIOIH»TED BIDBOCIIEOISS
ItCIITIOB; OUCBMBDtBE; DDT;
BOBtCBtOBl BBPTkCBlOB EPOIIDB;
DiaDBIB; BBIiCBlOtOCTClOBBIllE: DOB;
•mists; BISSISSIPPI
BBFBBBBCB
B«>. J.
Dari«s. D.J.
1978
CkCBOBpkBEB
7(9)1699-706
Bats, r.l.
StCBUBBB. S.C.
lobs. k.B.
1976
International lorkahop
on Biological spcclBM
ColUetion. IpclU
1976, Lonaboacg
-------
a.7-Rethano-18-lndene, l,2,3,a,5,6, 7,8,8-noaachloro-2,3,3«, «,7,7«-h«x«br not
given
50
S7
57
BAIGE
a) Rot given
b) Rot given
c) lot qtTen
4) lot given
e) Hot given
f) 1-2 ng/g
0-150 ppb
Trace- 0.01 ppa
Trace- 0.01 ppi
HEtl
at ag/g
b) ng/g
c) ng/g
4) ng/g
•) ng/g
f) ng/g
81 ppb
0.010 ppe
<0.0! ppi
OEREBAL HPOBBATIOB
e) Eastern Canada
b) Quebec
c} Ontario
d) Central Canada
e) testern Canada
f) Rational average, sasples above 1
ng/g
Rational Sarvev, 1975
BIPBSRTL COBPOOIDS; ClIlDti CBLOBIRE
OBGARIC COBPOORDS; DDE; DOT;
DIELDIXR; BEPTACBLOI EPOSIDE:
BBIACBLOtOBEEZBEE;
BUACBLOIOCICLOBEIAEE; BILK;
EORACBLOB; OZICBLOBDARE: PESTICIDES;
POLTCBLOBIRATED BIPBERTLS;
POLTCBL01IRATIO TBBPBERILS
Extracted llplds, Jan 1979 to reb
I960. 3-»6 day* postpartai. la
•Ignifleant correlation tilth
reeidence, age, veignt, naeber of
children previoaely nened, hoaeekold
aee of non-pec*l«tent peeticide>, or
occoMtian of epoase. Bigber, bet
nonelgnlfleant levels in no««» vlth
higher frequency of eeat eonmeptlon,
and In those in hones tilth pest
control treataent.
Bealthr 18-37 rr old Bavaiias
* DOLTS; «OI| UVAII; BILC
CBZORZBaTBD BTDBOC1BBORS; DDE: DDT;
DIZLDUE; BIUCBLOROCIC10HM1RI;
BSPTtCRLOI EPOCIDE;
BBZiCBlOlOBEBCBBB; URDIBB;
ROUCBIOB; OXTCBLOBD1RE; PESTICIDES;
mUCfltOaiElTEP BIPBERIIS; DIETS;
L1CT1TIOI; PESTICIDE BBSIDOZS;
POPOLtTIOl EXPOSOBB
Besidae levels «ere belon Instraeent
sensitivlti and could not be
confirmed.
Sasples fros 17 Begroes and 40
Caecasians in hospitals is irkansas
and aisslsslppi.
PESTICIDES; PESTICIDE BBSIDOBS; BILK;
POPOLMIOR EXPOSOBB; BaBfltlT SLMDS;
LlCtUIOBl BI01CCOBPL1TIOB;
HISSISSIPPI; 1BURSIS; PL1CERT1
It.11 positive saeples
Sasplss fron residents of irkansas
and Bississippi
PESTICIDES; ADIPOSE TISSUE; BILBl
ORIBB; BI01CCOIDLUIOR; BIPBBBXL
COBPODIDS; CBLOIIRlTBD BTDROCaBBORS;
1BURSAS; BISSISSIPPI
KEFERZIICE
Bee, J.
Davies, D.J.
1979
Balletic of
Environcental
contaelnatlon
and
Toxicology 21:381-387
Takahashl, ».
Saldln, D.
Takel. G.
long, L.
1981
Bulletin of
Environeental
Coataslnation and
Toxlcologr 27:506-511
Strassaaa, S.c.
lotx. r.v.
1977
Pesticides Ronitoring
Joarnal I0(«l:130-133
tat*, P.I.
Strasssaa. S.C.
tobs, A.I.
1977
Pesticide Banagesest
and Insecticide
Beslstance, Acadeslc
Press. Inc., Ren York,
Saa Prsaeisco, London,
(pp. 523-539)
-------
a,7-lethanolndaa, l.2,«,5,6,7.8.8-actnchloro-l.2-epoxv-3a,«.7.7a-tetrahvdro- (8 cil
- (9
C10-B4-C18-0
•• 423.77
tXSSUE
266
Bilk
267
Bilk
268
Bilk
269
Bilk
270
Bilk
BXPOSOBB BOOTS
ABAIITXCAL
BETBOD
GC
-
.
ac/as
ec
HOUSES
OF CASES
2
57
a) 10
b) 25
e| 35
4| 10
e) 20
f) Bot
given
1»36
1,436
•anple*
BABOB
0.09-0.17 ng
Trace-0.02 pp*
a) lot given
b) lot given
c) lot given
d) lot given
e) lot given
t) 1-2 ng/g
75.4-116.3 ppb
a) lot given
b) lot given
e) 13.2-5700 ppb
(IBXT
IEAB
0. 13 ag
S.C.
tobn, 4.B.
1976
International lorluhop
on Biological Speciaea
Collection. April.
1976, Laxenbonrg
Be*. J.
Oavie*, D.J.
1979
Bulletin of
Bavironaeatal
Contuinatlon aad
toxicology 21:381-387
Savage, B.P.
leefe, T.J.
Te**ari, J.D.
Iheeler. B.I.
Ipplehana, F.B.
Go**, B.I.
Ford, S.i.
1981
aierlcaa Jonraal of
Bpideniology
13S(*|:ai3-«22
•non
1977n
Peaticid* S toxic
Chanlcal lev*
5(8)110-11
-------
•,7-flethanoindan, 1 ,2,*.5.6.7,B,8-octachloro-1,2-epoxr-3a,*,7,7a-tetrihvdro- (B CI)
2,5-Bathano-2B-lndeno(l,2-b)OIirene, la,2.3,a,S,ta.7.7-octaehloro- la, lb,S, 5a.6,6a-hexahTdro- (9 CI)
26880-«8-8
CIO-BR-C18-O
HI B2J.77
(COITIROF.D)
TISSOE
271
Hi Ik
272
ail*, fat
273
•ilk.
dhole
27*
Bilk.
•hoi*
EXPOSOBE BOOT!!
UALTTICAL
ftBTHOD
GC
OC-EC
6C-BC
TI£
ec/ns
SC-BC
IOBBEB
OF CiSES
SO
•I 3*
b) 6
57
57
HINGE
11-160 ppb
a) 0.03-0.70 pp*
b) 0-0. 12 ppa
Trace- 0.02 ppa
Trace-0.02 ppa
SEAR
59 ppb
a) 0. 13 ppi
b) 0.050 PPB
0.012 ppB
<0.01 ppB
GEIEIAL IirOBBATIOI
Extracted liplds, Jan 1979 to F«b
1980, 3-16 days pOBtpartaa. «o
significant correlation »ith
residence, age. Height, auBber of
children previously naraed, household
am* of non-persistent pesticide*, or
occupation of spouse. Blgher, but
nonsignificant levels in losen vlth
higher frequency of eeat consnaption.
and in those la hoses vith pest
control treataent.
Healthy 18-37 yc old Havailans
ADDLTS; IGEj BAVAII; BILK;
CHtOIIIATEO BIDHOCalBOISl DOE; ODT;
DIILOHXI; BEZaCHlOIOCTCLOBEZU;
BBFTaCflLOl EPOXZDI)
BEIICBLOIOBEIZEIE; UIDlIEj
lOBtCBLOl; OZTCBLORD1IE: PESTICIDES;
•OHCHLOEZIkTEO BIPBEIILS; DIETS;
UCTITICM; PESTICIDE SZSIDITES;
POPDLiTIO EZPOSOIS
a) Bigh pesticide usage area
b) too pesticide usage area
Vosen living in SUrkvllle.
Mississippi (Ion pesticide usage) and
Delta area (high pesticide usage).
Saaples in 1973-1975.
BZlKi PESTICIDES; DDE; ODD; DDT;
BEZaCBLOROCZCLOBIZalEs BBPT1CBLOB
EPOZIDS) OZICBLOIOalB; DIZlDtll)
BISSISSIPPI; COaPiBlTITE BftLOaTIOIS;
8E1S08ERER BETBODS
Saaples fros 17 leg roes asd ao
Caucasians la hospitals in Arkansas
and Bississippi.
PESTICIDES; PESTICIDE RESZDOES; BTtlt;
POPDLHIOI EZPOSOIB: BABBalT filllDS;
LaCTlTZOI; BIOaCCOBOUTIOl;
BISSISSIPPI; UK1IS1S; PtlCBRI
•5.6 positive saaples
Sasples fros residents of irkaasas
asd Bississippi
PESTICIDES; ADIPOSE TISSUE; Bill;
OIIIB; BIOACCOBOLATIOI; BIPBEITt
COBPOOIDS; CBLOBIIATBO BIDBOCaRBOISl
AIUIS1S; BISSISSIPPI
KEFEHEICE
Takahashl. «.
Saldln, 0.
Takei, G.
long, L.
1981
Bulletin of
Bnvironsental
Contasinatlon and
Toxicology 27:506-^11
Barnett, B.I.
O'Ercole, A.J.
Cain. J.D.
Arthur. R.D.
1979
Pesticides Boaltorlng
Journal 13(2):* 7-51
Strassaaa, S.c.
Cats. r.l.
1977
Pesticides BositariBg
Journal 10 («) : 130-133
Zutl, F.I.
strassaan, S.c.
lobs, A.I.
1977
Pesticide Banageseat
end Insecticide
leslstance, Acadesic
Press, Inc.. le« Tork,
San Francisco. London,
(pp. 523-539)
-------
a,7-R*tkanolndan, I,«,5,6.7.8,8-aeptachloco-2.3-apo»r-3a,»,7.7«-t«tcabrdro- (8 CI)
2,S~Bathino-2H-iadeno(l.2-b)oxlrana. 2,3,«.5,6.7.7-heptachloco-1a.lb,5,5a,6,6a-h«xahydco- (9
l02«-57-3
C10-H5-C17-0
•I 389.32
nssoB
275
Bauacy
gland
276
Bilk
277
Bilk
276
•ilk
BXPOSOEB IOOTB
imTTXCll
SETHOD
CC
OC-BC
ec-BC
6C
IOHBB1
or cuss
•I 5
b| 9
c| 9
57
2
57
BaEGE
•) 0-0.59 ppa
b) 0-1.61 ppa
c) 0-0.51 ppa
Tcaca-0.03 ppa
0.05-0.10 ug
TracB-0.03 ppa
mi
a) 0.2336 ppa
b) 0.3506 ppa
o) 0.1282 ppa
0.012 ppa
0.08 og
<0.01 ppa
"" ~ (IBS! *»»«!
GEIEtAL IirORHlTIOl
a) Control
b) aallgoaat
c) Beaut Una* adjacut
uligaancy
•Baucaloc* apoxlda. nan* wad In
table, trail* baptachloc la aMd la
t«Kt.
to
t Isaac, adjacent to
appacaatly nocaal glandolac and
adipoM tlaaw at aloa iioaaa vlth
adaBocacclnoaa of t»« bccaat,
obtalnad fcoa the ».C. Caaacgo
Boapltal la Sao Paulo, laaaacr gland
and adjacaat adlpoa* tlsaa*
-------
•,7-lethanolndaa. I,e,S,6,7,8.8-heptachloro-2,3-epoiJ-3a.il, 7,7a-tetrahjdro- (8 CD
2>5-Bothano-2B-lndeno(t,2-b)oxiren<), 2.3,»,5.6,7,7-heptachloro-la,1b,5.5a,6,6a-hel«hydro- (9 CI)
!02»-57-3
C10-B3-C17-0
Bi 389.32
(CONTIIOED)
TISSUE
279
Hi Ik
280
Milk
281
Bilk
282
Bilk
ESPOSOEE BOOTS
UALYTICIL
BETHOD
GC
_
cc
tic
cc
GC/HS
IOBBBB
OF CiSBS
29
18
12 of 51
•1 10
b) 25
c) 35
d) 10
•) 20
f) lot
given
BalGF
lot given
0.6-2.6 ppb
lot given
a) lot given
b) lot given
c) lot given
d) lot given
•) lot given
f) 1-3 ng/g
NEAI
0.0091 ppa
1.57 ppb
0.0027 ppa
«) 1 ng/g
b) I ag/g
c) I Bg/g
d) 1 ng/g
a) 2 ng/g
f) 1 ag/g
GEIERAL IirOBHATIOR
Higher percentages of organochlorine
insecticides and PCB's In (ilk of
aotkers 20-29 years than 30-39.
although the Corner had loner levels
in plassa. Otarnalght nonea had
lover letela than vonan of Boreal
weight, lasidaea concentrated in
extracted liplda of plasea and ailk.
laraali vonan 2-* day* after nocnal
deliTery.
PESTICIDES: BLOOD PLiSBi; BILK;
fOPOLATIOl BXPOSDII; ISBIEL;
CB10UI1TBD BIDBOCalBOIS; IIPIDS;
AGE] DDT; DOD; DOB; POLTCBLOBII1TBO
BIFBEITLS; BBCT1CBLOI EMI IDE;
HEIlCBLOtOCICLOUIUHE
Bilk nanplee. honpltale in urban
Oslo. • manplen Iron Balllagdal, a
Taller in soathern larva r- lo
occapational axpoanre.
BILK: IISECT1CIDBS; UCTltlOl;
CBLOBZI1TID BI010C1RBOI3; CBLOBIIB
OIGaBIC COBPOOIDS; PESTICIDES; WllaT
landon eobjecta of greater St. Loais.
BO. Mtropoliton area.
PESTICIDES; CBLOIIIE ORGallC
COBfoaiDS; DDT j DDBj DIELDRII;
BIZiCBLOIOCTCLOBIUIBl BIK1CBLOR
BPOXIDE; BIU; BISSOOBI; COBFlBaTITB
STaLOlTIOIS
n) Eaetarn Canada
b) Qaebec
c) Ontario
d) Central Canada
a) lantern Canada
fj latlonal average , aaeplea abofe 1
ng/g
lational Sirvay. 1975
UVBniL COBPODIOS; CAIlDti CBLOIIIB
OBOallC COHPOOIDS; DOB; DDT;
DIBLDBII: BBPTICBLOB EPOIIDI;
BBXACBLOBOBBBZBIB;
BEI1CBLOKOCTO.OBIX1IE; BILE;
•OlaCBLOB; OITCBLOEDUE; PESTICIDES;
MUCBLOBIHTED BIPBBITLSi
POLTCBLOIXBalED TB1PBBIILS
BErEBEVCE
Pollahuk, Z.H.
Bon, H.
uaasereaan, n.
Coco«, S.
Kaiaarnann, D.
Leneaeh, c.
1977
Pesticides Bonitorlng
Journal 10 («) : 12 1-129
Bakken, A.r.
Selp. H.
1976
acta Paadiatrlca
Scandina*iea 65:535-539
Jonason, T.
Lla. O.J.I.
Irebraster, J.
(ettelhat, L.L.
Dracker. B.
1977
inerican Journal of
Clinical latrition
30:1106-1109
Ben. J.
Darie*, O.J.
1979
Bulletin of
EnTironeental
Contaaination and
Toxicologr 21:381-387
(IBXI PAGE)
-------
4,7-HatkanoiBdaB, l,*,5,6.7,8>B-kaptacblora-2.3-apozf-3a,*.7,7a-tatcakvdro- (8 CI)
2,5-aathaBO-2B-lnaaao(l,2-b)ozirana, 2.3.«.5,6,7,7-haptBCkloco-la,1b,S,5a.6.6a-hazahrdro- (9 CX|
!02»-57-3
cio-as-a.7-0
IB 389.32
(COlTIIOED)
TISSUE
283
Bilk
28*
Bilk
285
Bilk
286
Bilk
EXPOSDBE BOOTS
Xngastion
AULTTICAL
BBTBOO
GC
GC
GC
IOHBBB
OF CASES
a) 27
b) 10
c) 10
d) «0
a) 21
b) 2«
c) «S
d) «S
1436
l,«36
PAIGE
a) 0-0.008 ppa
b) 0-0.21 pps
c) Bot givaa
4) 0.001-0.00* pps
,,,.,,
a) 0-0.296 ppa
b) 0-1.002 ppa
c) 0-1.002 pps
d) Bot givan
66.1-128 PPB
a) lot givaB
b) lot glvaa
c) IS. 2-20 SO ppb
BEAI
a) 0.007 ppa
b) 0.003 pps
c) 0.002 pps
d) 0.003 ppa
-
a) 0.017 ppa
b) 0.051 ppB
c) 0.035 ppB
d) 0.0003 ppa
91.* » oc - 125.2 PPB
a) 66. 1 ppb
b) 128 ppb
c) lot givan
GEIEBAL XirOIBATXOI
a) Cotton, cocn, and sasasa-groniBg
araa
b) Con araa
c) Baaana acaa
d) Coffaa-groning acaa. El Salvador
a)-c) in Gnataaala. Bighast asa of
pasticidas OB cotton
VOSBB f cos Ion lacoaa fasiilass in
Oaatasala and El Salvador, ckosaa to
raprasBBt diffarant dagraas of us* of
pasticidas.
Ovarasa of pasticidas a particalar
problaa in tropical cooatrias.
Prevalence of aalautritlon aaj
CQBtribata to kaaltk effects.
AGBXCOLTOBE; CBLOBXBB OBGABIC
COBPOOIDS; CBOP DUSTIlO; an;
DIBLDIII; EL SALTADOB; fOOD
COtTABIIATIOl; GOATBBALA;
BEXACBLOIOCTCLOBIXAII; BEPTACBLOB
EPOXIDX; XISBCTXCIDBS; BXLK;
lOtBXTXOlU DEPXCIBICXBS; PESTICIDES;
PESTICIDE BBSXDOES
B) lacal Botkacs, fat basis
b) Orbaa sotbsrs. fat basis
c) All aotkaca. fat basis
d) All aotkars. nhole silk basis
Oats Cot sas of all pasticidas and
coapaciaoss «ltk valoas of otkar
invaatigatoca glvaa
iBrsing sotkars f COB Cordoba cagloa.
Spaia
SPAII; ADULTS; BILK; CBlOzIlE OBGAIIC
COBPODIDS; PESTICIDES; A8BICOLTOBB:
IDIAL ABBAS! OBBIB ABBAS
coapatad oa fat adjnstad basis
Bange of aaans for all gaogcapkic
regies*
Incsiog aotkars, O.S.A.
OBXIBO STATES: ADULTS; BILK;
COHPAIATITB ETALOAIXOBS; CBLOIXBB
OBOABXC COBPOOIDS; DIBLDBIB;
PESTICIDES; LACTATIOI
.
a) Eortknest, U.S.
b) Southeast. U.S.
c) latloaiida saapla, bigkast laval
fros tka Soatkaast region
OIXTBD STATES; BILK; DIBLDBII)
BBPTACBLOB EPOXXOB; OXICBLOBDAIE;
PESTICIDE BESXDOBS; POPOLATIOI
BXPOSOBB
BEFEBEICE
4* Caapos. 1.
Olsxrna-BanTs. A.E.
1979
Arcklvas of
BBVlCOBBBBtal
Contaaination and
Tozicologv B:«3-58
Pozo Loca, B.
Baccara Hacteacka. A.
Polo Tillar, L.a.
Lopaz-Oiaaaaz, 1.
Jodral fillacejo. <|.
Xglasias Paras, J.
1979
Bavista Bspanola da
Padiatrla
35(206)593-110
Savaga, E.P.
Kaafa, T.J.
Tassari, J.D.
Bbaalar, B.l.
Applakaas, T.a.
Goes, B.A.
Ford, S.A.
1981
Asaricaa jotcnal of
BpideBiologv
133 (*):« 13-422
Anoa
1977s
Pasticlda 8 Toilc
Ckasical lava
5(8)110-11
(KBIT PAGE)
-------
a,7-Bethanolndan, I,»,5,6,7,8,8-heptachloro-2,3-epoxy-3a.»,7,7a-tetrahy4ro- (8 CI)
2,S-Bethano-2fl-iBdeno(l.2-b)o«lrene. 2,3,*.5,6,7.7-heptachloro-1a.1b.S.5a,6,6a-hexahydro- (9 CI|
I02S-S7-3
C10-B5-C17-0
NV 389.32
(coiniaeo)
TISSOB
287
Bilk
288
Bilk, fat
289
Bilk, fat
290
•ilk.
!•>*•,
•hole
EXPOSORE BOOTE
ABALTTXCAL
HBTBOD
GC
OC-BC
GC-EC
TIC
GC/BS
GC-EC
BOBBEB
or CASES
50
a) 53
b) 33
a) 3«
b) 6
57
RANGE
1-67 ppb
a) Not detectable-0.060
Ppa
b) lot detectable-0. 113
ppi
a) 0.02-0.37 ppa
b) 0.01-0.08 ppa
Traee-0.03 ppi
HB1N
35 ppb
a) 0.002 ppi
b) 0.028 ppi
a) 0.08 ppi
b) 0.050 ppi
-------
a,7-Rethanoiaaea«. l.a,5,6,7,8, a-hept«chloro-3a.».7,7a-tetraliraro- (a CD
«,7-BathaBO-IB-iadaM. I,«.5,6.7,8. e-heptachloro-3a,«.7.7a-tetrahrdco- (9
CIO-B5-C17
MB 373.35. Hf 95-96 C. »P 3X10(B-«) an 89 at 25 C
cil
TISSOE
291
BlU
292
Ulk
UPOSOSB BOOIB
- -
Ingeation
MUnZCU.
RETROD
OC
OC
IOHBBB
OF CA3BS
3 of 51
al 21
b| 2«
C> as
4| «5
B1ICE
lot given
a) O.«05-I0.823 ppa
b) 0.615-11.686 ppa
e) 0.105-11.686 ppa
d) Not given
. ._,
mi
0.019 ppa
a) 2.556 ppa
b) 2.«62 ppa
c) 2.505 ppa
d| 0.0390 ppa
GEIERAL UrOERATIOl
Raodoa subjects ol greater St. tool*.
10, aetropolitan «r«a.
PESTICIDES! C8LORKB ORGAIIC
couponDS; DOT; OOB; DIELORH:
BBUCBLOIOCIClOBnaVBi HEPItCHlOB
IMIUBi BIIJC; SlSSOoai: COBPJIRUIVE
ETU.01TIOIS
a) local aotbaca, fat baala
b) Ocbaa aothar*, fat bail*
c) all aotaecc. Cat bails
d) all aothaca, «hol« aiUt basl*
Data foe an* of all paaticIdea aad
coapaciaocB vlth Talma of othac
lanattga tor* gi«w
lacaing aothars fcoa Cordoba ragioa,
Spain
SPkll; iDOLTSt BlUCi CB1OIIIB ORGtIIC
COBVOnOS; PESTICIDES: aclZCOlTOBB;
BOUL AREAS 1 OR BAR AREAS
(EfEREICE
Joauoa, 1,
Lin. G.J.K.
Acabrntac, J.
(cttelhat. t.l.
J>raek*c. B.
1977
Aaaclctn Journal of
Clinical lutrltloD
30:1106-1109
Peso Loca, R.
Bacceca Bacteach*. A.
Polo Tillar, L.B.
lopaz-Oiaaaax, R.
Jodcal TllUrajo, n.
Igleaiaa Paces, J.
1979
Rariata Bapaaola d«
Padiatcia
35(206):93-IIO
5-Xhia-1-axabicyclo (*. 2.0)oct-2-ena-2-oacboryltc acU, 3- (((5-aathyl-1,3,a-thiadiazol-2-rU thio) aathylt -B-oio-7-(J- (IR-tatraxol-t-fl) acataaido) - (8 CI)
5-thia-1-azablcjclo(».2.0)oct-2-»na-2-cacboijUc acid, 3-(((5-aothyl-l.3.«-thiadlaiol-2-rl)thio)aatliTlt-8-oxo-7-((1H-tatta«ol-1-rlac«til)aaiao)-, (6R-tcana|- (9 CI|
25953-19-9
cii-HU-ne-oa-33
RB «S*.S, HP 198-200 C
TXSSOE
293
Bilk
,,
EXPOSDBE SOOTB
Injection
AIALITICAL
BBTBOO
Hl:cobio logical
IOHBBR
or CASES
20
RAISE
1.16-1.51 ug/al
BBAf
tat given
.
OEIIRAL IirORBATIOR
2-* he after injection of 2 g. Peak
at 3 he.
lactating •oaan in Japaa
AITIBIOTIC5: MOOS: DRUG TBBRAPI;
ADO-TSi JAPAl; BUMP SBROBI HLH:
LACTATIOI
REFEBEICE
loahioka, B.
Cho, K.
Takiaoto, B.
Bacayaaa, S.
Shiai*a. T.
1979
Journal of Pediatrics
9»(1): 151-152
00
acrtanlllde. «'-hrdcoir- (S d)
acataalda, •-(t-hrdcoijphanrl) - (9 CI)
103*90-2
C6-B9-B-02
flf 151.16, HP 169-170.5 C
zxasoB
29*
Bilk
_
EIPOSOBE IOOTB
Ingaation
ARALITICAl
BETHOD
BS
•oasER
or CASES
3
RUGB
26.5-29. 1 u aol/1
BEI*
27 u aol/1
GBIBRAL IirORBATIOl
Peak laral vitaia 2 he after 500 eg,
f Bating. Bean acea under
concentration- tine cor»e, 115. 0 «oc-
29.3 naoi hc/1
Beeaat feeding ne«d not be
diacontinoed vitb con>antioaal doaaa
Lactating voaan, ages 2*. 29, and 31
I*
AOOITS; BLOOD PL ASK A; Hill:
1IALSBSICS1 ARTIPTBETICSj OROG
TBERAPIl DROOSI lACIATIOl
--
RErEREBCB
Bitian, P.-O.
Gaatafaaoa, B.
Joatell. t.G.
Belander, A.
tahlin-Boll, B.
1981
Buopeaa Joacnal of
Clinical Phacaacologr
201123-125
-------
Caffeine (8 CI)
1B-Purln«-2,6-dione. 3.7-dihrdro-l,j.T-triiethrl- (9 CI)
58-08-2
C8-B10-14-02
H» 19*.19, HP 238 C
TISSOB
295
ailk
BXPOSOBB ROOTS
Ingestion
9
AIALTTICAL
HETBOS
TL:
oc
.
IOHBBR
OF CASES
a) 1
b) 1
RAIGE
a) 1300-400 ng/el
b) 1600-200 ng/nl
&) dot appllziblo
b) lot applicable
GEIERAL IIFORHATZOI
a) I.S and 12 hr. Initial
aeaenresent 600 ng/el at O.S hr
b) 3 and 48 hr. Initial aeasnreaent
1000 ng/el at O.S hr
Estimated froa graph
Dose 64 ag, plus 324 ng phenacetln,
454 *g aspirin and 60 ag codelae
phosphate
30 and 32 yr old nursing eothers
ADULTS; BLOOD PLASMA; BILK;
AIALOESICS; OROGS; IARCOTICS;
LACTATIOI
REFERBICE
J.U.A.
I. R.L.
B.F.
HelCh. B.3.
Findlay, J.n.
1961
Clinical Pharaacology
and Therapeutics
29 (5): 625-633
Batradiol (8 CI)
B«tra-1.3.S(10)-trl«na-3,n-dlol, (17b«ta|- (9 CI)
50-28-2
C18-H24-02
HR 272.«2. HP 173-179 C
TISSUE
296
Bilk
8XPOSOSB BOOTS
-
fajinal
alaLTTICal
HBTROO
Bit
BOHBBB
or CUBS
a| 3
b) 3
HUGE
a) 27-1000 pg/sl
b) «0-250 pg/U.
IE1B
a) lot applicable
b) lot applicable
CEIBRtL IirORBaTIOl
a) 50 19 ••ppoiitoty. Paaki at 3- It
kr
b) 100 ag suppository. Peaks at 3-6
hr
Ranq* of observed Talaes ap to 23 hr
after dose.
Bealthr lactatlng voluteecs.
StBBOIDS; BOIBOIES) HIUl LaCIiTIOl)
BE1SVREBBIT BET BODS; BBtLTB BAIUDS
_
RBrBS£BCE
Bilsson, S.
lyoren K-6.
Johansson, B.D.B.
1978
aserieaa Joarnal of
Obstetrics and
Sfaecologr
132 (6): 653-657
Ieidaxole-1-ethanol, alpha-(Bethoxyaethrl)-2-nitro- (8 CI)
IB-Iiidaxole-l-ethanol, alpha- (neithoxraetbrl)-2-nltro- (9 CI)
13551-87-6
C7-HI1-13-04
ai 201.11
1 TISSUE
297
Bannarr
gland
BXPOSORE ROOTE
-
Ingestion
1IU.TTICU,
BETBOD
BPLC
„ _
IUHBEB
OF CASES
t
.
RAISE
3-«2 ug/g
_ .
BEAK
lot applicable
e
OBIBRAL IirORBATIOl
I and 4.3 he after noraalizad dose of
1 g/«q •
Estiaated froa graph. Biopsies of
toaor
Patient nith breast otrciaoaa
ADOLTS; CARCIIOBASi BELAIOBASl BLOOD
PLASBA) CERBBSOSPIIAL PLOID; BABBAIT
CLAID3; DB04 THBRAPI; DR08SJ
CORPallTITB ETALOATIOISl CHBBOTHIRAPT
RBFBSEICE
Dische, S.
Saaadera, H.I.
Biley. P.J.
Baock, J.
Bennett. a.B.
Stratford, a. R.I.
Hinchlaton, A.I.
1981
British Journal of
Cancer 43:344-349
-------
L-Prolina, 1-(3-Mrcapto-2-aethTl-l-oxopEOpTl|-, (S)-
62571-86-2
C9-BIS-B-03-S
•• 217.31
TXSSOE
298
•ilk
EXPOS OU BOOTS
lagastion
llaLITICAL
BBTBOD
1LL
6C/BS
BOBBEB
OF CUBS
11
BAH6B
•) 1.8-3.0 ng/nl
b) Bat given
e) 2.2-5.5 ng/sl
niB
a) lot given
b) 2.0 ng/sl
c) Bot given
SEIBRIL IIFORRaTIOB
s) 1 hr after doses 1, a, 7
b) about 8 hr after dose 6
c) 0.5 and « he after dose 7. Final
seasueMst 3.0 *9/al at 8 hr
Range of seans. estimated (roe graph
100 ng 3i/day |7 louts). Bean peak
level 1.7 ng/sl at eeaa tiee of 3.8
hr. Bean ADC 22.9 ng hr/nl
Levels slgnif icantlv lo«ec than those
in blood
Bealthr 21-35 jr olds. «t 50-86 kg
ADULTS; BLOOD: BILK; aBTIBIPEBtBISITS
aflntSi OBOG TBBBaPTi OBOBS;
laCTMZOB
REFBBEBCE
Oevlia, t.G.
Fleiss, P. 8.
1981
Journal of Clinical
Fhacsacologr 21:110-11)
Borphinan-6alpaa-ol. 7,8-didebT (5«lpha.6alpha)- (9 CI)
76-57-3
CI8-B2I-B-03
BI 299.36. HP I5*-1S6 C (after drying at 80 C|
I'" TH8SOB I
299
Bilk
nnsoBK soon
Ingestion
tBtLTTICaL
IBTBOO
Bla
., ,, , . , . ,.
•09BEB
OF C1SES
2
BaBGB
a| 500-20 ng/nl
b) 2-20 ng/nl
c) 500-5 ng/nl
d) 8-3 ng/nl
BBiB
a) lot applisable
b) Hot applicable
c) Hot aprlisable
d) Dot applicable
BBIIBM. IBVOIBHIOB
a) 1 and 12 hr. Initial neasuresent
105 ng/nl at O.S hr. subject 1
b) 0.5 and 12 hr. Betabolit*
(norphine). subject 1
c) 1.5 and la he. Initial seasvrmeat
300 ng/nl at 1.0 hr, subject 2
d) 1.5 and 36 kr. Betabolite
(norphine), subject 2
Dos* 60 ng as phosphate, pins 45* ng
aspirin. 32* ng phenacetin and 6* ng
caffeine
Estinated froe graph
30 and 32 vr old narsing nothers
aOOLTS; B10OD FL1SB1; BILK;
UUBtSICS; OBOOS) BAICOTICS;
UHBIBI: LiCTaTIOB
RBFBBBBCB
Findlaj, J.B.a.
OeUgelle, I.I.
Kenraer. B.F.
HelCh, B.B.
Findlay, J.H.
1981
Clinical Fharnacologr
and Therapeutics
29(51:625-633
-------
p-icetophenetidide |8 CI)
acetaaide, l-(«-ethoxyphenyl)- (9 CI)
62-4I-2
C10-B13-I-02
B* 179.21, HP I3*-I3S C
TISSUE
300
Milk
EXfOSUBE BOOTE
Ingestion
UILTTICIL
NETaOD
li
IOBBEB
OP ClStS
2
R1RGE
- .
•) 500-3 oq/nl
b) ISOO-SOO ng/sl
c) 2000-15 ng/al
d) 1500-50 nq/el
HgiN
a) Hot applicable
b) Dot appll:able
s) lot applicable
d) lot applicable
GEIEBAL IIFOtllTIOl
a) O.S and 12 he, subject 1
b) 3 and 12 he. Initial aeasureaent
700 ng/al at O.S or. Pheaacetln
aetabolite (acetasinophen, subject 1)
c) I and 7 he, subject 2
d) 2 and 2* he. Initial seasuresant
800 ng/sl at 0.5 he. Phenacetin
setabolite (ac H.P.
Belch, B.H.
Pindlar, J.fl.
1981
Clinical Pharaacologr
and Thecapautlcs
29(5(1625-633
Ijcidozol (8 CI)
3,«-PrcidlnedisetaaDOl, S-hrdcoxr-6-aethrl- (9 CI)
65-23-6
C«-BU-W-03
•I 169.18. IP 160 C
TISSOE
301
Bilk
EXPOSDBE BODTE
Ingestioo
UlLItlCiL
BETBOD
Btecobio logic*!
IOBBRB
OP CUBS
a| 6
b) 8
e) i
UIGE
a) 67-177 ug/1
b) 189-3*8 ug/1
c) 256-(5* ng/1
mi
•I 129 » oc -
b) 239 » or •
c) 31* • oc -
6EIEI1L IIPORHaTIOl
a) < 2.5 •« B-6/daT
b) 2.5-5.0 sg B-6/day
c) > 5.0 sg B-6/dar
Bo effect of stage of lactation.
Bealthf, lactatlng 2«-*2 re olds.
Hill; IBOIaBa; flTlUISi DIETS i
UOaTIOl
BEPB1EICE
lest. K.D.
Klekser, 1.
1976
isecican Joacnal of
clinical latcitioa
29:961-969
Salicylic acid (8 CI)
ic acid, 2-hTdcoir- (9 CI)
69-72-7
C7-B6-03
BB 138.12, BP 157-159 C, BP about 211 C at 20 ea Bg
TISSOE
302
Bilk
EIPOSOBB BOOTB
.
Ingestion
allLTTICal.
BETHOD
1
|
IOBBEB
OP CaSBS
*) 1
b) 1
RkBGE
a) 0.27-1.0 ag/al
b) 1.5-0.2 ug/sl
BEkl
a) lot applicable
b) lot applicable
CEIEI1L IBFOgBaTIOl
a) 0.5 and 2 he after «5« sg. Pinal
•easaceaent 0.8 ug/sl at 12 fee
b) 1.5 and 2* he after *s« sg.
laitial seasureaent 0.9 ag/sl at 0.5
he
Estisated fcos gcaph
Dose included 32* ag phenantin, 6*
ag caffeine and 60 sg codeiae
phosphate
30 and 32 ye old nursing aothecs
aOOLISi BtOOD PLaSBl; BILK;
aBUOBSICS} MOBS) lUCOTICSj
CtPPBTIB; LaCMTIOl
UPEIEICB
Findlay, J.I.I.
Oeangelis. B.L.
Kearney, H.P.
Belch. B.B.
Pindlay. J.B.
1981
Clinical Pharnacology
and Therapeutics
29 (5) S6 25-633
-------
Salicylic acid, lon(l-) (8 CI)
Benioic acid. 2-kvdroxj-, ion(l-) (9 CI| (Til)
63-36-5
C7-B5-03
RB 138.12, IIP 157-159 C. BP aboat 211 C at 20 •• Bg
TISSUE
303
Bilk
BIFOSOU iOOTE
Inga*tion
A1U.TTXC1L
BBTBOO
HPLC
BOBBEB
OP CaSBS
6
BalGE
a) 0. (2-0. 78 ag*
b) 1.20-2. II ng«
C) 1.80-0.81 aqf
RE1I
a) 0.5S agl
b) 1.60 ag«
c| 3.87 19%
GElim nroBBlTIOl
a) 2-« hr after 500 ag
b) 2-6 kr afMr 1000 ag
c) 2-* hr after 1500 19
Idaiaiaterad aa 500 eg acetyaallcylic
add tablet* 1 kr after breakfaat
Peak level*
Healthy naming aotken, 24-32 yr old
(Man 29 yr). «6-65 kg (Man 58 kg).
2-8 ao poat-partu (MM 5 ao)
ADOLtS; BILK; U1LOE5ICS;
ainPTRBTICSi DI08S; ttCTatlOB;
BETtBOLITBS
kBPEBEICB
Jaaall, F.
taakavacx. B.
1981
Iat«raatlonal Jooridl
of Pkataacaatlca
8:285-290
Salicylic acid, S-((p-(2-pyridylaalfaaoyl)pk«nrl)axa) - (8 CI)
Baniolc acid, 2-hyiroxy-5-((«-((J-pyrldlnylaaUo) aoltoayl) pkanyl)azo)- (9 CI)
599-79-1
CI8-HU-»«-05-S
Bfl 398.39, BP 2«0-2*S C (dacoip)
TISSOB
30*
BXPOSOBB BOOTB
Ingentlon
IHLTTIClt
BBTBOD
IDBBBI
or CISBS
3
BaBBB
a) Bot given
b) lot given
c) lot given
d) lot given
aiki
a) 2.7 » or - I.B
eg/el
b) 10.3 » or - 1.6
ng/al
c) l.» » or - 0.7
ug/al
d) 0.8 » or - 1.0
ug/al
GBBnil nrOBBlTXO*
a) Solpkacalasine
b) total nlphapvrldlM
c) aeetflated •olpkapycldlaa
d) aeatvlated aolpkapvcldlM
gloewonlde
Beanxed 1 *k after delivery. Ooee,
0.5 g *z/day daring pregnancy and
pMrperlaa.
Patients witk aloerative eolitl* vho
becaae pregnant vnile on taecapy.
tlHOTIC VLOIOl BLOOD SBBOBi
015TIOIII85TU1I. SISTBBi BILK;
OBBUIUL COM! D»06 TBBBkPI; DBOS3;
BBTkBOLISBi BBTkBOtlTBSt PBB«BkICTi
UCT4TIOI
BBPBBBKB
Kkan, *.(.*.
Troelove, s.c.
1979
Brltiah Medical Journal
2(620*1:1553
Snlfaallanlde, B(l|-(3,*-dlaetkyl-5-iaozazolrl|- (8 CI)
Beneneealfonnnlde, a-amlBO-B-(3.*-dinetkyl-5-laoxaiolyl)- (9 CI)
127-69-5
C11-B13-B3-03-S
B« 267.30, BP 19* C (alao reported 195-198 C. 192-195 C)
TISSUE
305
Bilk
EIPOSOII BOOT!
IngMtlon
1I1LTTIC1L
BBTBOD
BORBBB
OF CISBS
6
BlaGZ
n| Dot given
b) lot given
c) Hot given
d) lot given
mi
a) 18 » or - 8.1 ng
b) Q.*S » or - 0.21*
c) 22.8 » or - II. 5«
d) 77.1 « or - 11. 5«
GBBmi nrOBBkTIOB
a) Total aaitlnozaiole
b) S of aaternal doee
c) * of total aalfinotaxole recovarad
ae •alfinozasole
d) * of total nalfiaoxatole recovered
an B«-acetyl ealfUonsole
DOM 1.0 g every 6 kr far 2* kr, *8
kr collection period
CnncnaUnn, agee 19-27 yr
SOtFOIiBI DBS ; BIOICCOBOtaTIOB i
UCUTIOIt BtTlBOLITBSi UBStS;
aDOUSl BUR) DROSS
IBrBIIICE
Kauffnaa, I.B.
O'Brien. C.
Ollford, P.
1980
Pedlatric*
97 (5)1 839-8*1
-------
Theobcoelce (8 CI)
1B-Parlne-2.6-dlone, 3.7-dlhrdro-3,7-dlaethrl- (9 CI)
63-67-0
C7-B8-I»-02
III 180.17, DP 357 c, BP 290 C (Sabllaes)
TISSUE
306
ailk
EXPOSOBE EOOTE
iBgestiOB
-
AlaLTTIClL
BBTROD
HPLC
--
IORBE8
OF CUBS
_
6
BJUGE
3.7-7.5 ag/1
HE ill
5.3 my/1
GEIEBiL IRFOBH1TIOI
After 113 9 ailk chocolate containing
2*0 ag theobroaine sad 16 ag
caffelae. Peaks at 2.1-3.3 he.
Caucasian*. ages 21-36 re. »t 55-70
kg, nursing th«ic lataats 3-37 vk.
Slight nausea IB 3 Bothers, BO
adverse effects OB infants.
BLOOD PLASBA; BILK; SALIVAl DROGS;
UCtltlOI; IIFAITSl FOODS
REFE8CICE
Bessan, B.H.
Bluseathal, H.p.
Josko, I.J.
1977
Journal of Pediatrics
91(3J:«77-«80
Theophrllin* (8 CI)
IB-ParlB«-2.6-dlOBe, 3,7-dihydro-1,3-diMthrl- (9
58-55-9
C7-B8-I4-02
Bi 180.17, IIP 270-27* C
CII
nssaz
307
Bilk
EIPOSOU BOOTt
iBJSCtiOB
-
alUTTICIL
BBIHOD
HPLC
IOBBEB
OF CASES
a) I
b) I
c) 1
HUGE
a) 12-6.5 ug/al
b) IO-«.5 ug/sl
c) 5.7-2.7 og/Bl
RBkl
a) lot giren
b) lot given
c) lot glran
GEIEItL IirOBBtTIOl
a) 30 and 330 sin after 3.2-5.3 ng/kg
b) 30 and 330 sin after 3.2-5.3 sg/kg
c) 30 and 300 sin after 3.2-5.3 sg/kg
2S-32 yr old asthsatics
BLOOD FLJLSIi; BIUC; DRUGS) lotOIda 1C
DIOBBWCS
BBFEIEIC8
Stec. G.P.
aceenberger, P.
lao, T.I.
Beathorn. T.
Borito. I.
atkinson. a.J., Jr.
pattersoo, I.
1980
Clinical Pharsacologr
and Therapeatics
28(3):«0«-«08
Oracil, 6-propjl-2-thio- (8 CII
*(1B)-Prcieidinone, 2,3-dihldco-6-propyl-2-thioxo- (9 CI)
51-52-5
C7-BIO-I2-O-S
B* 170.25
TISSOE
308
Bilk
EXPOS DIE SO DTE
IngsstioB
allLTTICaL
BITBOD
Badloaetrf
, -
• DBBEB
OF C1SIS
1
UIGB
0.0003-0.000 IX
radioactive dose/Hi
BBtl
lot gifea
GBIBB1L IIFOBB1TIOI
6 sad 2« BE after 100 ag
propTlthiaaradl coatalalag 100 uci
labelled drag
Bilk: serna non-proteia bound S
acti»iti ratio • 0.55.
Lactating Bother
DB06S; D«DC TBBUPTl BLOOD SBBOB;
BILKl L1CT1TIOI; SCOTLalD
BBFEJBICS
LOU, L.C.K.
Lang, J.
Ilezander, l.D.
1979
Lancet 2(8ISO): 1011
-------
TaUrlc acid, 2-propyl- (8 CI)
Pentanoic acid. 2-propyl- (9 CI)
99-66-t
C8-B16-02
Hi 1M.21. BP 120-121 C at 1« •• g9> 128-130 C at 20 » flg
TISSDE
309
Bilk
BIPOSOHB BOOTB
Xagaatioa
IBktlTXCat
1BTBOD
OC/HS
BOHBBB
OF CUBS
a|
b)
el
41
•1
fl 1
BIBGE
a) 2.2-5.4 ng/al
b) 0.034-4.7 ng/al
c) 0.«5-O.T2 ag/al
d| 0.12-1. OS ag/al
•I 1.2-1.5 ug/Bl
I| 0.18-1.6 ug/Bl
BB1«
a) Vat given
b) 1st gl*en
c) tot gi»«B
d) lot gi**n
•I lot given
f| lot glT«n
GUEltL HrOBBlTIOl
•) 4-20 d«T« postnatal (pn). Do«a
31.0 ig/kg/a>T> S»co» levels
83.3-102.2 »g/»l
b) 5-29 day* p». Don 10.1 ig/kg/dar.
Secu, «.74-96.3 ag/il
c) 3-25 day* pa. Don 9.6 aq/k«/day.
SUU, 10.2-32.8 ag/il
d) 38-»7 day« pi. DOM 9.5
ag/kg/day. Saraa 7.6-26.8 ag/al
•I 4-12 day* pa. Don 26.7
ag/kg/day. plo> 7.« pc
Seraa 33.3-«4.6 «g/al
f) 7-82 day* pn. Dos* 25.8 ag/kg/day
pin 5.0 ag pnaaytoln/kg/day. Scraa
15.2-73.8 ag/al
Data alao glvea for aetabollta.
lpil*ptica
6 cf 8 Monataa developed ictacu
aacaatocaa. Hlnoi abaocaalltiaa »ec«
hacalaa, dlaataals of anacnlas caotaa
abdoalaia aad vaak abdoalaal valla.
2 vece alcrocephallc
IDUtTS) rmS| IBIBOM! CIRUL
H1TOOS STSTIB DZSMSIS; BUHW SBBORi
UUi aBHOOBfOUaRSt DIBS I88BWI;
DBOOS; UCT1TIOI; BBTkBOLItES;
BBFBBBICE
laa, B.
Bating, D.
Koch, s.
Bauaec, I.
Ralge. B.
1981
Journal of Paacaacology
aad Bipaciaantal
Therapeutics
219 (3): 768-777
S3
l-Plparasineetkanol, «-(3-(2-(tcieiaocoMthyl)-9B-thioiantken-9-ylidana)propyl-. (II-
53772-82-0
C2*-B25-F3-»2-0-S
n «3«.5«
XXSSDB
310
•ilk
BXPOSOBB BOOTB
IBtLITICaL
BBIBOO
BIk
BORBBB
OF CUBS
3
B1BGE
0.8-1.8 ng/al
BBH
1.6 ng/al
UBBB1L IBFOBBtXIOB
»-»! day a poatpartaa. Secua levels
1.3-1.5 ag/al. Doaa. 2 ag/day or »0
ag/2 »k or 60 ag/3 ak
BBIBOBB; MBIOtIC rtOIDi BIOOD SBBOBl
BlUtl DB08 IIBBaVZ; DlOflS;
TBUQUIlinBSi UCTMIOB: PBMBUCI
BIFBMBCB
Kirk. i.
Jorgaaaan, a.
1980
Psychopharaacology
72:107-108
-------
1.2-Propaaedlol, 3-(2-Bitroiaidaxol-l-yl)- (8 CI)
1.2-Bropaeediol, 3- (2-Bltro-1B-lalda»ol-1-rl- (9 CD
13551-92-3
C6-B9-B3-O*
HI 187. IB
TISSUE
311
Baaaarr
gland
EIPOSORE SOOTK
lagastioa
AEALTTICAL
SSTHOD
BPIC
H01BBB
OP CASES
23-33 ttg/g
nit
lot applicable
GEBBBAL IEP08BATIOI
1 and « he after BOraaliztfd dose of 1
g/sg •> final aaasareaeat 27 «g/g at
».5 hr
Bstiaatad Croc graph. Biopsies of
tiuor
Patient vita boast catclaoM
ADULTS: CABCIBOflAS; UlABOBAS; BIOOO
PLASBA: CBBBBBOSPMAL PtOID: BABBABI
GIABD3: D10B TBEIlPI: DBDSSi
COBMUTITB BIlLDitlOBS; CBMOTBBB1PI
lEPBBEICK
.
Oi»ck«, S.
S*aBd«ci, fl.l.
Pil«T, P.J.
Hauck, J.
B«DD«tt, U.S.
Stratford, a. E.I.
BlbChiatOB, a. I.
1981
British Joaraal of
Caac*r *3:3*«-3*9
18, l9-DiBor-nalp«a-pr«gn-a-«n-20-7n-3-oa«, l3-«thfl-IT-krdrozr-, (»-)- (8 CII
l8,19-DloocpragB-«-«B-20-TB-3-OBa, l3-«tBJl-17-Brdro«r-. (Halphal-(»-| - (9 CI)
6533-00-2
C2I-B2B-02
BB 312.a*. HP 2)8-2*2 C (» foral. 239-2*1 C (- fora)
TISSOE
312
•ilk
Binsou BOOTS
iBqostioa
AHLTTIC1L
BBTBOD
Bit
IOBBB1
OP C1SIS
15
B1B8B
a) 0.16-1.50 ng/Bl
b) 0.29-2.50 ag/Bl
C) 0.08-0. *S Bg/al
d) 0.16-0.63 ng/al
•I 0.11-0.66 acj/sl
£) 0.22-1.10 nq/al
g) 0.06-0.20 nq/al
a| 0.10-0.30 Bq/al
11 Boaa da tact *d
1) BOB* dstactafl
BB1B
a) 0.51 ag/al
b| I.OS ag/Bl
c) 0.22 og/al
1| 0.38 ng/al
•I 0.3* ag/al
f) 0.5* Bg/Bl
g) 0. II ag/al
h) O.IT Bg/al
1) Bot applicable
j) Bot applicable
6EIU1L IIPOEBtTIOl
a) Pnaualag. 3 hr after 250 ag » 50
ag etklarl estradlol
b) Postaarsing, 3 kr after 250 ag •
50 ag etaiarl estradiol
c) PreaarsiBg, 23 he after 250 ag »
50 ag etkUyl estradiol
d) Postasrsiag, 23 he after 250 ag •
50 ag ethiBTl estradiol
•} Presarsiag. 3 he after ISO ag • 30
•9 ataiarl estradiol
f| Postaarsiag, 3 hr after 150 ag »
30 ag etaiayl estradiol
g) Preaarslag, 23 hr alter 150 ag »
30 ag ethlail estradiol
h) PoetaersiBg, 23 hr after ISO ag »
30 ag ethisil estradiol
i) freaarsiBg. 3 hr after 30 ag
j) Poataarsiag, 3 hr after 30 ag
•ilk expressed before aad after
reediag tise
Lactatlag Ceaales la Svedea
SHOBI; AOOLS; BIOOD PLASBAi BUJt;
PBO«B3TO6nS; COBPABAtlfl
ETAlOAtlOBS; LACtAIIOI
BBrBBBBCB
IllMOB, S.
Brgrea, I.
JoaasssoB. B.O.B.
1977
Aaerlcaa Joaraal of
Obstetrics aad
Craecologr 129:178-IB*
-------
3-B*ptBBOB«, 6- (dia*thrl«aiBO) -*>»-diph«ajl-
76-99-3
C2l-B27-i-0
Hf 309.«9
TISSUE
313
Hllk
BXKSOBE tooiE
lagMtloa
APILYTXCU
IZTBOD
oc
fOBBEI
or cuss
19
UME
0.05-0.57 og/»l
_.
BE1B
lot gi* «thyl «»t«r (S CI)
1B-Imld«zol«-1*c«cbozrllc «cld. 2,3-Ukrdxo-3-Mthrl-2-tUoio-. (tkyl
22232-5*-S
C7-H10-B2-O2-S
» 186.23. BP 122-125 C
(9 cl)
TISSOB
3U
•ilk
IXPOSOBB ROOTS
ABU. TTICll
BETHOO
Badloaatcr
_.
BURBEB
OP CA5BS
1
BAI6Z
0.003-0. 0006S radloactlva
dOM/Bl
HBIB
Bet gi»«n
8EBBUL nPOIUTXOB
1 aad 2* br aftar 10 ag carblaacol*
coatataiig 100 ad labaUod drag
Blllu MCIB Boa-protalB booad s
actl*itr ratio » 1.05.
lactatlag aotkor
DBBBSi DBOO TBMAPT; BLOOD SEBOli
BXII; llcntXOB; SCOTlaBD
BEPEBEBCB
Lo«. t.C.K.
1979
Laacat 2(8150): 101 1
•-S*t«-1-«Mblejclo(3.2.0|li»BtM«-2-c«rboxTllc acid. 6-(2-«»l«o-2-(p-hTdto«ipfc»«yl|«e«t«mldo|-3.3-dl««t»il-7-oxa-. 0- (8 C1J
«-Thi.-l-««blcrclo{3.2.0|h.pt.M-2-c.rboxiuc acid. 6- ((••iBO(»-lirdro«TPk««Tll«e«tjl| .miBo|-3.3-oi.i«tkrl-7-«o, (2S-|2«lpk«.S«lPk«,6b.t«(S»JM- (9 Cl|
26787-78-0
Ct«-B19-B3-O5-$
HI 36S.ll, IP 19* : (b*ta-Bapkthtl«BMoUoB«t« tcikrd»t«|
TXS9DB
315
Bilk
BXPOSOBB ROOTB
lagMtioa
iliLTTICU.
BBTBOO
BO BBBS
OP CUBS
6
UB6B
0.10-0.81 og/Bl
nil
13 1 gi»B
dlBAL IBFOBB1TXOB
1 ud S kr «ft«r 1 g. rlaal
••••mnMDt. 0.60 tg/mi at 6 kr
luo* of msaas
UOtTS; BLOOD SBBOB; BUB;
IBTIBIOTICS: OB003; UCT1TIOB
BBPBSBBCB
Bafvtslc. 0-».
siafu, c.i.
eaorgakopovloa. P.I.
Papadatoa, C.J.
1981
icta Pa«diatrtea
ScudlaMlca 70:285-288
-------
5-Thla-l-azablcvclo(*. 2. 0|oct-2-»a«-2-caeboxrllc acid, 3-((acatyloiy) aathyll-7-(((2-«alno-0-thlaiolyl| (a»tho«yialno | acatyll aaloo)-8-oro -, (6B-tr«na)-
60M6-21-1
C16-B17-R5-07-S2
•g (55.20
TISSOE
316
Hi Ik
EXPOSOBE BOOTE
Injection
ARALTTICAL
NBTBOD
Microbiological
ROHBEB
or CASES
12
BARGE
0.32-0.13 ug/al
HEAR
Kit given
GSREBAL IRPOBHATIOI
2 and 6 he alter 1 q. Initial
neaaaceaent, 0.15 ug/al at 0.5 he
Bange of aaana
ADOLfS; BLOOD SEBOH; HILK;
AETIBIOTICS: OROGS; LACTATIOR
REFERERCE
Katetzia, O.A.
Slafas, C.A.
Geoeqakoponlos. P.A.
Papadatoa. C.J.
1981
Acta Pavdlatelca
Scandinavica 70:285-288
S-ma-l-azabicrclo(*t 2.0)oct-2-*oa-2-carboirlic acid, 3-(hrdroifaethrl| -8-oio-7-(2-(2-tblanyl| acataaldoi - acetite (aatac) (8 CI)
5-ThU-1-aublerclo^v2.0)oct-2-«B«-2-carboirlic acid. 3-((acatrloxy) aathrl)-8-oio-7-( (2-thienylacetrl) aaino) -, (6H-tcan»>- (9 Cl
**
Cl)
C16-B16-B2-O6-S2
BW 396.aa
TISSOB
317
Bilk
BJPOSOEE KOOTB
lojection
kllLTTICAL
BEIHOO
Hlccobio logical
ROSBEB
or CASES
6
B1IGE
0.»7-0.16 og/al
HEAR
Rot glien
GEREBAL IRFOBBATIOR
2 and 6 he after 1 g. Initial
aeaaaroaent, 0.27 ag/nl at 0.5 he
Bange of neana
AOOLTS; BLOOO SBBOB; BILKl
ABTIBIOTICS; OR DOS I LACTATIOR
REPEBEKCE
Eafetxin, D.A.
Slataa. c.A.
Oeocgakopouloa ,
Papadatoa, C.J.
1981
Acta Paedlatcica
Scandinavica 70:
P.A.
285-288
5-Thia-1-axabicycL>(4.2.0) oct-2-ana-2-carbox7lic acid. 3-(hrdcoxr»thrl) -B-oxo-7-(2-(a-prrldrlthio) acataaldo)-, >c«tat« (ut«c) (BCD
S-Thla-1-azabicrclo(a.2.0)oct-2-aB«-2-carboxrUc «ci4, 3-|(ac«trloxr)a«thTl)-8-oxo-7-( ((H-pyrldinylthlolicatyl) jalno)-, (6R-trana)- |9
C17-B17-R3-06-S2
BB »23.»9
TISSOB
316
Bilk
._
BXMSOBB ROOTS
Injection
AEALITICAL
BBTBOD
BlcEObiologica 1
•OBBBR
OF CASBS
6
BABGE
O.H3-0. 16 ug/al
RB1R
tat gl»«n
OERERAL IRFORUTIOR
2 and 6 kr after 1 g. Initial
Ma*o»Mnt, 0.26 ag/nl at O.S he
Bang* of aaana
ADOITS) BLOOO SBBOB; BILK:
ABTIBIOTICSi OR08S| UCtATIOB
BBFESERCB
Kafatzis, O.A.
siafas, C.A.
e*ocgakopoalos, P.A.
Papadatoa, C.J.
1981
Acta Pacdlatrica
ScandinaTlca 70:285-288
S-Tkla-1-axabicTClo(il. 2.0)oct-2-ana-2'cacbozrllc acid. 7-((aalao (0-hydcoiyphenyl) acetyl) salno)-3-a«thyl-8-o«o-, (6B-(6alpka.7b«ta(l*M>-
90370-12-2
CI6-HI7-B3-05-S
BB 363.«2
TI3SOE
319
B1U
__
BKNSOBB ROOTB
Ingawtlon
ABALITICAL
BBTBOD
Blccobiological
BOHBBB
OF CASES
6
0.10-
BARGE
BEAR
Rot given
GEREBAL IRFOBRATIOR
1 and 6 aft«e I g. Final
awaiaranatnt. 1.16 ag/nl at 8 he
Bang* of Mann
ADDLTS: BLOOO SBIOB; BILE;
ABTIBIOIICSl DROOSi LACTATIOR
BBFEBERCB
Kafetxl*. O.A.
Siafan. C.A.
Gaocgakoponlo*, P.A.
Papadatoa. C.J.
19BI
Acta Paadiatcica
Scandinavian 70:285-288
-------
5-Thia-1-axabicyclo(«.2.0)oct-2-«n«-2-c«rboiyllc add, 7-(2-aalno-2-phanylacetaaldo)-3-a«th7l-8-oxo-, 0- (8 CZ)
S-Thia-l-axabicycloja. 2.0)oct-2-aBa-2-carboxylic acid, 7-((a*lBopheBylac«tyl)aaino)-3-a*thyl-B-oxo-, (6B-(6alpha.7b*ta(k*)))- (9 CI)
i5686"'1~2
ci6-an-ij-o»-s
BS 3*7.«
TISSUE
320
Bilk
-
1IP030RB BOOTS
Xngaatlon
HULTTICIL
SET BOD
fllccobio logical
IONBBB
OF CiSBS
6
BaBGE
0.20-0. SO ug/al
BE* I
lot gl»B
GEIBBU. XIFOBBaTXOB
1 and » he altar 1 g. Flaal
m«a«araMnt 0.32 og/al at 6 he
Bang* of MA»
tDOltS; BLOOD SIB OB; IILX;
1RIBIOTICS; DEOGS; LICtiTIOl
BBFESBNCB
KaC«txi<. D.a.
Sla(a«, C.I.
(••ocgtkopoulo*, p.i.
Papadatoi, C.J.
1981
icta PMdiatclea
ScandUavlca 70:285-288
SB-Dlbens (b,C) axapiac-5-cacboxaBia*
298-4C-*
C1S-BI2-B2-O
BB 236.26. HP 20«-206 C
tissue
321
Bilk
BXPOSOBZ BOOTS
tHLITICat
BBIBOD
IOBBBR
OF CISBS
1
BalGE
. ._ .
a) lot glT«n
b) lot gl*en
c) lot gi»«o
d) lot gl*«B
•1 lot gl*«n
1} lot gi»«n
HBal
a) 7.5 a aol/1
b) 2.6 a 10 VI
c) 5. 5 a col/1
a) 1.8 a lol/l
•) 7.5 a BOl/1
f) ».* a BOl/1
GBIBAI. IIPOIUHOI
•) Cacba>«z«pln«> 2nd day
b) >0. ll-«poiy cacbaaaMpln*
(Mtabolltc) . 2nd d»
c) Cacbaiauple*. 3rd day
d) 10, 1 1-«poiy carbauxapin*, 3rd day
•) Cacbaiax«pln«, 30th day
f) 10,11-«poxy carbaaazapina. 30th
day
Patient took 8 agAg c«cbaaaxapln«
aad 6 «g/kg dlphaaylhydaatloB daily
dorlag gcstatloa aad lactatloa.
OBOES; BLOOD; laCTaTIOli IBVBOBI;
BBTaBOLXTBSl BILK
BBPBIBICB
Pyanoaan, S.
Slllanpaa, n.
1975
LaneMt 2|793*):S63
-------
REFERENCES FOR THE DATA TABLE
t.
I960
Baaans: Overview of Busan Exposure to Dieldrln Residues ID the Environment and Currant Trends ol Besilue
Levels in Tissue
Pesticides Bonitoriag Joarnal 10(2): 64-69
idasovic. T.H.j Sokic, B.; Ssiljanski. a-J
1978 •
Sose Observations Concerning the Batio of the Intake of Organochlorlne Insecticides Through Food and
mounts Excreted in the Bilk of Breast-feeding Bothers
Bnllatin of Environmental Contaaination and Toxicology 20:280-285
toon
1977
•hat's in Br«a«t Bilk?
Lancet 1(80I7):918
1977a
Breastfed Babies at Bi«k in Beavy Pesticide Ose areas. Survey Shows
Pesticide 6 toxic Cheaical ie«s 5(8): 10-11
1977c
PCBs and child Bearing
Foliation 7(1) :6
1978a
BP1 Survey Shows Chesicals in Breast Bilk of larsing O.S. Rosen
Chesical Bagnlation Reporter 2(24) :9
Bakken. l.F.; Seip, B.
1976
Insecticides in Bnsan Breast Bilk
»cta Paediatrica Scandinavica 65:535-539
Barnett, B.I.; O'Brcole, ».J. 5 Cain, J.D.: Arthur, B.D.
1979
Hasans. Organochlorine Pesticide Besidaes in Hasan Hilk Sasples fros Rosen Living in Borthvest and
Bortheast Blssissippi, 1973-1975
Pesticides Bonitoring Joarnal 13(2):»7-51
Bell, B.B. ; Brown, 8.J.; Bilner, B.t Sinclair, J.C.; Zapursky, k.
1979
Titasin B absorption in Saall presature Infants
Pediatrics 63 (6): 830-832
Bitxen, P.-0.; Gastafsson, B.; Jostell, K.e.; Mlander, t.; Rahlin-Boll, B.
1981
Excretion of ParacetasoX in Hasan Breast Bilk
European Joarnal of Clinical Pharsacology 20:123-125
Blinick, O.j Znturrisi, C.B.; Jerex. B.j Ballach, B.C.
1975
Bethadone assays in Pregnant Bosen and Progeny
aserican Journal of Obstetrics and Gynecology 121(5):617-621
Bory. C.: Baltassat, P.; Port ha alt, H.; Bethenod, B.; Frederich, 1.; aranda, J.T.
1979
Betaboliss of Taaopkylline to Caffeine in Presatnre Bewborn Infants
Journal of Pediatrics 9« (6):988-993
Bowering, J.; Sanehex, a.B.t Irwin, H.I.
1976
I Conspectus of Research on Iron Begnireaents of Ban
Joarnal of Botrition 106(7) :985-107*
Boyle* B.H.; Highland, J.B.
1979
The Persistence of PCBs
Bnvironsent 21 (5) :6-13,37, 38
Bradt, P.T.; BerrenkoU, B.C.
1976
ODT in Busan Hilk - ihat Detersines the Levels?
Science of the Total Bnvironsent 6:161-163
-------
94
Srevik, E. H.
1978
Gas Chroaatograpaic Method foe the Determination of Organochlorine Pesticides in Hasan Bilk
Bulletin of Environmental Contamination and Toxicology 19:281-286
Brevik. E. R.; B jerk, J. E.
1978
Organochlorine compounds ia Borvegian Hasan Pat and Bilk
Acta Pharmacologica et Toxicologica a3(1):59-63
Brilliant, L.B.; Aaburg, 6.V.; isbister, J.; Buaphrey, B.; iilcox, K.; E rater, J.: Blooaer, I.R.; Price, B.
1978
Breast-Bilk Honitoring to Beasare Bichigan's Contaaination with Polybrominated Bipheayls
Lancet 2 (8091): 643-606
Byrne, I.E.; Kosta, L.
1978
Vaaadiua in Foods and in Hasan Body Plaids and Tissues
Science of the Total Environment 10:17-30
Carrie, H.A.; Kadis, f. B.: Breitkreitx, i.E.; Cunningham, 0.B.; Brans, O.I.
1979
Pesticide Residues in Hasan Bilk, Alberta, Canada-1966-70, 1977-78
Pesticides Monitoring Journal 13 (2):52-55
de Caspos, B.; Olszyna-Barzys, 1.8.
1979
Contamination of Hasan Bilk vith Chlorinated Pesticides IB Guatemala and in El SalTador
archives of EnTironsental Contaaination and Toxicology 8:43-58
Deichmana, B.B.: HacDonald, i.E.
1977
Organochlorine Pesticides and Liver Cancer Deaths in the United States, 1930-1972
Ecotozicology and Environmental Safety 1:89-110
Devlin, B.6.: Pleiss, P.B.
1981
Captopril in Hasan Blood and Breast Bilk
Journal of Clinical Pharaacology 21:110-113
Dickinson, B.C.; Borland, B.C.; Lynn, B.K.; Smith, B. s Gerber, B.
1979
Transmission of Talproic Icid (Depakene) across the Placenta: Half-life of the Drag in Bother and Baby
Journal of Pediatrics 9« (5):832-835
Dillon, J.C.; Bartin, C.B.; O'Brien, B.T.
1981
pesticide aesidues in Hasan Bilk
pood and Cosaetics Toxicology l9:«37-«»2
Dische, S.; Saanders, B.I. j Biley, P.J.; Baack, J. ; Bennett, fl. H.; Stratford, B.B.L. : Binchinton, I.I.
1981
The concentration of Dessethylsisoaidazole in Haaao Tosoars and in Cerebrospinal Plaid
British Journal of Cancer 13:300-319
Donckel, I.E.
1975
In Updating on the Polybroainated Biphenyl Disaster in Hichigan
Journal of the Iserican Veterinary Hedical Association 167(9): 838-841
Erickson, H.D.; Harris, B.S.B., ZXZ; Pellizzari, E.D.; Toser, K.B.; Haddell, B.D.i Bhitaker, D.I.
1980
Acquisition and Chesical analysis of Bother's Bilk for Selected Toxic Sabstances
EPi 560/13-80-029, 153 pp.
Ferguson, B.B.; Ills on, DuJ.; Schaffner, I.
1976
Deter si nation of Bicotine Concentrations in Hasan Bilk
laerican Journal of Diseases of Children 130:837-839
riadlay. J.i.i.; Delngelis, H.L.; Kearney, B.F.; Belch, B.H.; Pindlay, J.H.
1981
Analgesic Drugs in Breast Bilk and Plassa
Clinical Pharsacology and Therapeutics 29 (5)-.625-633
-------
95
Finley, J.P.: Ba»an, I.B.; Song, P.T.; Lickrish, G.B.
1979
Dlgoiin Biccetioo In Hunan Hilk
Journal of Pediatrics 94 (2) :339-340
Franssor, G-B.; Lonnerdal, B.
I9SO
Iron in Hasan Hilk
Joarnal of Pediatrics 96 (3): 380-384
Fry, B.H.; laves, D.B.
1974
Haternal and Fetal Flaoroaetabolite Concentrations after Exposure to Hethoxyflorane
kserican Joarnal of Obstetrics and Gyaecology 119(2): 199-204
Fujita, B.; Takabatake, E.
1977
Bercurr Levels in Hasan Haternal and leonatal Blood, Bale and Hilk
Balletic of Environmental Contasination and Toxicology 18(2):205-209
Galster, w.i.
1976
Bercury in Alaskan Bskiso Bothers and Infants
Environmental Health Perspectives 15:135-140
Graca, I.; Fernandas, A.B.S.S.; Boarao, B.C.
1974
Organochloriae Insecticide BesiAaes ia Hasan Hilk ia Portugal
Pesticides Hoaitoring Joarnal 8(3): 148-156
Gathrie, B.E.; Bobinson, H.F.
1978
The latritional Status of leu zealanders vith Respect to Hanganese, Copper, Zinc and Cadaiaa - 1 Berle»
lev Zealand Redical Journal 87 (6 03): 3-8
Harrod, J.B.; asgnith, B.T.
I960
Pollutants in Breast Bilk
Hen England Joarnal of aediciae 303(16):945-946
Boldrinet, H.T.H.; Brann, H.E.; Frank, R.; Stopps, o.J.; Saoat, H.S.; Bciade, J.B.
1977
Organochloriae Besidues in Hunan adipose Tissue and Bilk fros Ontario Residents, 1969-1974
Canadian Joarnal of Public Health 68:74-80
Haaphrey, H.2.B.; Bayner, I.S.
1975
Polybrosinated Biphenyls: an igricnltnral Incident and Its Consequences. II. In Bpideniological
Investigation of Hasan Exposure
Trace Substances in Environmental Health - IX, 0.0. Heaphlll (Bd.), Proceedings of University of
Hissouri'8 9th Annual Conference on Trace Snbstaaces in Environsental Health. University of Hissoari,
Colasbia, HO pp. 57-63
Irvia, H.I.; Hntchias, B.K.
1976
* conspectus of Research on Titaain c Requirements of Baa
Joarnal of Butrition 106 (6): 823-879
Janali, F.; Keshavarz, B.
1981
Salicylate Excretion in Breast Bilk
International Joarnal of Pharnaceutics 8:285-290
Jonsaon, T.; Lin, G.J.K.; Arabraster. J.; Kettelhat, L.L.; Or acker, B.
1977
Chlorahydrocarbon Pesticide Residues in Hasan Bilk in Greater St. Louis, Hissouri 1977
aserican Journal of Clinical lutritioa 30:1106-1109
Kafetzis, O.I.; Siafaa, c.l.; Ceorgakopoulos, P.I.; Papadatos, C.J.
1981
Passage of Cephalosporins and Isoxicillin into the Breast Bilk
Acta Paediatrica Scandinavica 70:285-286
-------
96
Kamp-.ann, j.*.: Haasen, J. H. ; Johansen, K.; Heliteg, J.
1980
Propylthiouracil in HUB an Bilk. Eerisioo of a Dogma
Laacet 1 (8 171) : 736-738
Kashimoto, I.; Niyata, H.; Kunita, H.
1981
The Presence of Polychlorinated Quaterphenyls in the Tissues of Tusho Victims
Food and Cosmetics Toxicology 19:335-340
Kanffman, E.E.; O'Brien, C.; Gilford, P.
1980
Sulfisoxazole Secretion into Human Bilk
Pediatrics 97 (5): 839-801
Khan, l.K. t. ; Truelove, S.C.
1979
Placental and Bammary Transfer of Salphasalazine
British Bedical Journal 2 (6204): 1553
Kirk, l.; Jorgensen, *.
1980
concentrations of Cis(Z)-flupentixol in Maternal Serai, Inniotic Flaid, Osbilical Cord Serus, and Rilk
Paychop barmacology 72:107-108
Kleaser, H.n.; Body, 1. H. ; Takahashi, I.; Ha ley, T.J.
1977
Human Tissue Distribation of Cyclodiene Pesticides—Hawaii 1960-1973
Clinical Toxicology 11(1):71-82
Kodasa, B.; Ota, B.
1980
Transfer of Polychlorinated Biphenyls to Infants fros Their Bothers
archives of Environmental Health 35 (2):95-100
Kodric-Ssit, B.; Slit, Z. ; Oil*, K.
1980
Organochlorine Contaminants in Baian Bilk froi Slafonia Province, lagoslavia, 1978
Pesticides Honitoring Journal 14(1): 1-2
(Coos, B.J. : Longo, L.O.
1976
Hercury Toiicity in the Pregnant Bosan, Fetus, and levborn Infant
American Journal of Obstetrics and Gynacology 126(3):390-409
Kuipolainen, J.; Tuori, E.
1980
Longitudinal Stud; of Chromiai in Hnian Bilk
imerican Journal of Clinical lotrition 33:2299-2302
KQipnlainen, J.; Toori, B.; flakiaen, S.; Kara, B.
1980
Dietary Chromium Intake of Lactmting Finnish Bothers: Effect on the Cr Content of Their Breast Bilk
British Journal of Intrition 44:257-263
Kutz, F.I.; Strassiaa, S.c.; lobs, i.B.
1976
Surrey of Pesticide Besidues and Their Hetabolites in the General Population of the Onited States
International Borkshop on Biological Specimen Collection, Ipril, 1976, Luxelbourg
1977
Survey of Pesticide Besidnes and Their Betabolites in Humans
Pesticide Banageient and Insecticide Besistance, Academic Press, Inc., Rev lock, San Francisco, London,
(pp. 523-539)
Longhnan, P.B.
1978
ffigoxin Excretion is Human Breast Bilk
Journal of Pediatrics 92 (6): 1019-1020
Lou, L.C.K.; Lang, J.: Alexander, B.D.
1979
Excretion of Carbisazole and Propylthionracil in Breast Bilk
Lancet 2(8150): 1011
-------
97
Mamj.. i, T. ; Kagava, B.: Kuroki, H.; Kuratauna, H.; Yoabiaura, T.; Taki, I.; Kusnda, H.: Tasaahita, t.;
flayaahi, 0.
1978
Transfer at Polyshlorinatad Biphanyls fros Bothers to Foetuses cod Infants
Food and Coaaatlca Toxicology 16:543-546
HUB. a.} Davies, D.J.
1978
Variation in the Polychlorlnated Blphenyl and arganochlorina Pesticide Residues During Hnaaa aceastfeellng
and It« Diurnal Pattern
Chaaoaphera 7 (9): 699-706
1979
Presence of Polychlorlnated Btphanyl and Organochlorine Pa at lei da Besidnes and the Absence of
Polychlorinated Tarphenyls In Canadian Buaan Bilk Sasplas
Bulletin of Environmental Contaaination and Toxicology 2It381-387
N«a, J.; Daviaa, O.J.; Lao, P.-I.
I960
Tha Effact of Extraction Tachnig.ua on tha rat Contact, Polrchlorinatad Bipbanyl Laval and Ttl- to
Octabiphanyl Diatcibution in Buaan Bilk
Chaaoaphata 9:763-769
Maa. J.; Oavlaa, D.J.; Milaa, H.
1978
Tracan of Hire i in Soaa Canadian Huaan Bilk Saaplaa
Bulletin of Bnviconaantal Contaaination and Toxicology 19j564-570
aillar. B.H.; Pinbarg, L.
1977
Pollutant* in Braaat Bilk
Journal ot Padiatcica 90 (3): 510-512
Ballay, B.i.; Pace, 0.0.; Pan, 0.R. ; Bya, R.B.; Bonld. J.J.; Siddla, B.C.
1978
Placenta 1 Iranafar of Chlorthalidooa and ita Bliaination in Batacnal Bilk
Bnropaan Journal of Clinical Pharmacology 13:129-131
Buaial, C.J.; Bntziagac, 0.; Zitko, T.; Crockar, J.
1974
Praoance of PCB, ODE, and DOT in Buaan Bilk in tha Prorinca* of Bav Brunswick and Bova Scotia, Canada
Bullatin of Environaantal Contaaination and Toxicology 12(3):258-267
Ban, B. j Bating, D.; Koch, S.; Hanaar, I.; Halga, B.
1981
Talproic acid and Its Batabolitea: Placantal Transfer, Baonatal Pharaacokinatics, Tranafac via lother's
Bilk and Clinical Status in laonataa of Epileptic Bothers
Journal of Pharsacology and Ezpariaantal Therapeutics 219 (3) :768-777
lilsson, S.; Bygren K-C.j Johansson, E.O.B.
1978
Transfai of Bstradiol to Bnsan Bilk
inerican Journal of Obstetrics and Synecology 132(6): 653-657
Bilsson, S.; Bygren, K.; Johansson, E.D.B.
1977
d-Borgestrel Concentrations in Batarnal Plasaa, Bilk, and Child Plassa During Idainistration of Oral
Contraceptives to Bnrsing Roeen
aserican Journal of obstetrics and Gynecology 129:178-184
Picclano, B.F.; Guthrie, H.I.
1976
Copper. Iron, and Cine Contents of Batnre Bnaan Bilk
aserican Journal of clinical Bntrltion 29:242-254
Pit kin, B.B.; Bahns, J.I.; Filer, L.J., Jr.; Beynolds, H.A.
1976
Bercnry in Buaan Baternal and Cord Blood, Placenta, and Bilk
Proceedings of the Society for Bxperlsental Biology and Bedicine 151:565-567
Pittard, ».B.; Bill, K.; Fletcher, B.D.
1979
Excretion of Technetius in Bnnan Bilk
Journal of Pediatrics 94 (4): 605-607
-------
98
Polis! uk, Z.l.; Bon. M. ; iassermann. H.: Cucos, S. ; Rassermann, 0.; Lemesch, C.
IS77
Pesticides in People
Pesticides Monitoring Journal 10 (U) : 121-129
Polo Villar, L.H.; Hecrera Harteache, A.; PozoLora, E.; Lopez Gimmenez, B.; Jodcal Vlllarejo, H.; Iglesias
Perez, J.
1979
Bexachlorobenzeno (HCB) en Lecbas Humanas Espanolas
Bevista Espanola de Pediatria 35(207-208) :271-278
Pozo Loca, B. ; Hecreca Harteache, A. ; Polo 7iliar. L.S., Lopez-Gimenez, 8.; Jodral Tillacejo, H.; Iglesias
Perez, J.
1979
Plagaicidas Organoclocados en Leches Humanas Bapanoloa
Berista Espanola de Pediatria 35 (206):93-110
Pynnonen, S.; Sillanpaa, B.
1975
Carbamazepine and Bother's Bilk
Lancet 2(7930) :563
Bajalakshmi. K.: Srikantia, S.G.
1980
Copper, Zinc, and Hagneaiam content of Breast Bilk of Indian Vomen
American Journal of Clinical nutrition 33:669-669
Besman, B.B.; Blnmenthal, H.P.; Josko, >.J.
1977
Breast Bilk Distribution of Theobroiine froi Chocolate
Journal of Pediatrics 9 1 (3) :477-«80
Savage, B.P.; Keefe, T.J.; Tessari, J.D.; Hheeler, H.W.; Ipplehans, r.H.; Goes, E.I.; Pord, 5.1.
I9S1
Rational stud; of Chlorinated Hydrocarbon Insecticide Residues in Hasan Bilk, OS1
Iserican Journal of Epidesiology 133(4) :a 13-422
Sarage, E.P.; Tessari, J.D. ; Halbcrg, J.i.; Bbeeler, H.B.
1973
1 Search for Polychlorinated Biphenyls in Hasan Bilk in Bural Colorado
Bulletin of Environmental Contamination and Toxicology 9 (*): 222-226
Shan, J.c.i.
1976
Evidence for Defective Skeletal Bineralizatlon in Lo*-Birth»eight Infants: The Absorption of Calcium and
Fat
Pediatrics 57(1): 16-25
1980
Trace Elements in the Fetus and loung Infant II. Copper, Manganese, Selenium, and Chromium
American Journal of Diseases of Children 134:74-81
Shearer, T.B.; Hadjimarkcos, D.H.
1975
Geographic Distribution of Selenium in Human Bilk
Archives of Environmental Health 30(5): 230-233
Siddigoi, H.K.J.; Saxena, B.C.; Bhargava, A.K.; Seth, T.D.; Krishna Horti, C.R.: Ratty, D.
1981
Agrochemicals in the Haternal Blood, Bilk, and Cord Blood: A Source of Toxicants for Prenates and Heonates
Environmental Research 24:24-32
Smith, A.B.; Picciano, B.P.; Bilaer, J.A.
1982
Selenium Intakes and Status of Human Bilk and Formula Fed Infants
American Journal of Clinical Butrition 35:521-526
Stacey, t.I.; Thomas, B.B.
1975
organ ochlorine Pesticide Residues in Human Bilk, He stern Australia - 1970-1971
Pesticides Monitoring Journal 9(2):64-66
-------
99
St«c, G.P. ; Greenberger, P.; Ruo, 1.1.; Henthorn, T.; Horito, I.; Atkinson, A.J.. Jr.; Patterson, H.
I960
Kinetics of Theophylline Transfer to Breast Bilk
Clinical Pharmacology and Therapeutics 28 (3) : 104-908
Strassman, S.C.; Kutz, P. H.
1977
Insecticide Residues In Haman Hi Ik from Arkansas and Hississippi, 1973-79
Pesticides Honitoring Journal 10 (4): 130-133
Szokolay, A.; Boaival, L. ; Ohnak, J.; Badacie. A.
1977
Dynamics of Benzene Hexachloridm (BBC) Isomers and Other Chlorinated Pesticides in the Food Chain and in
Susan Pat
Ecotozicology and Environmental Safety 1:349-359
Takahashi. i. ; Saidin, D. ; Takei, 6.; Hong. L.
1981
Organochloride Pesticide Besidaes in Hasan Bilk in Hawaii, 1979-80
Bulletin of Environmental Contaaination and Toxicology 27:506-511
faughan, L.*.; Beber, C.R.: Kemberling, S.B.
1979
Longitudinal Changes in the Hineral Content of Huaan Bilk
Asecican Journal of Clinical nutrition 32:2301-2306
Bassermann, 0.; logneira, O.P.; Tomatis, L.; flicra, l.P.; Shibata, B.; Acie, G.; Cncos, S.; iassersann, D.
1976
Organochlorine Compounds in Beoplastic and Adjacent Apparently lorsal Breast Tissue
Bulletin of Environmental Contasination and Toxicology 15(4) :478-484
Best, K.D.; Kirksey, A.
1976
Influence of Vita Bin B6 Intake on the Content of the Titaein in Hasan Bilk
Aserican Journal of clinical lutrition 29:961-969
Best, B.8. ; Bilson, D.J.; Schaffner, I.
1975
Hezachlorophene concentrations in Hasan Hilk
Bulletin of Environmental Contamination and Toxicology 13(2): 167-169
Restoo, G.
1974
Changes in the Levels of Environmental Pollutants (Hg, DDT, Dieldria, PCS) in Some Swedish Poods
Ambio 3(2) :79-83
Bestoo, G.; Boren, K.
1978
Organochlorine Contaminants in Human Hilk, Stockholm 1967-1977
Ambio 7 (2) :62-64
Bickizer, T. B.; Brilliant, L.B.
1981
Testing for Polychlorinated Biphenyls in Human Hilk
Pediatrics 68 (3): 411-415
Bickizer, T.H.; Brilliant, L.B.; Copeland, B.; Tilden, B.
1981
PolTchlorinated Biphenvl Contamination of Bur sing Bothers' Bilk in Hichigan
American Journal of Public Health 71 (2): 132-137
Binter, H.; Thomas, H.; Bernick, S. ; Levin. S.; Farvar, H.T.
1976
Analysis of Pesticide Besidaes in 290 Samples of Guatemalan Bother's Hilk
Bulletin of Environmental Contamination and Toxicology 16(6) :652-657
lakushiji, T.; Bmtanabe. I.; Knwabara, K.; Toshida, S.; Hori, S.; Fnknshima, S.; Kashimoto, T.; Kayama, K.;
tunita, B.
1979
Levels of Organochlorine Pesticides and Polychlorinated Biphenyls (PCBs) in Bothers' Hilk Collected in
Osaka Prefecture from 1969-1976
Archives of Environmental Contamination and Toxicology 8:59-66
-------
100
rakushiji, T. ; iMtanabe, I.; Kuuabara, ».| Yoehida, a.; Koyaia, K.j Kunita, I.
1979
Level* el Polychlorlnated Biphenyla (PCBe) and Organochlocine Peatioidee in Hunan Milk tad Blood Col*«ct«d
in o»«k« Pr«f«ctur« fro* 1972 to 1977
Int*caatioaal tcchi*«> of Occupational and EnTironaaotal Health M3i1-1S
Toahida, 3.; Rakaaura, ».
1979
Residual atatua after Parturition of Rathylaalfone Netabolltee of Polfchlorlnated Bliihenyl* in the Brent
Milk of a Foriec Ziployee in • capacitor ractorr
Balletic of Bnvironiental Contamination and Toilcology 21:111-11}
roihioka, H. ; cho, n. j Takieoto, H. i Harofaia, 3.| ahliixu, T.
1979
Transfer of Cefaxolin into Hunan Milk
Journal of Pediatrice 94 (1): 151-152
-------
101
INDICES
CAS Preferred Name, page 103
CAS Registry Number, page 107
Chemical Synonym Name, page 109
Keyword, page 122
-------
103
C»S tCftUttfi N«B« lBd«I
Aotanillda, 4«-hydroiy- (8 CI) | loaUald*, B- (4-hydroiypbanjri) - |« ci| 29«
Atocblor 1254 I
Baoxaoa, cbloco- 2
B«ni*na, dlohloro- J
B«nz«o«, baiaobloco- 4-1«
Baniana, pcotacbloco- IS
B«Bi«aaaulfonaalda, 2-ohloco-S- (1-hydroiy-3-oxo-1-taalodollayl) - (• CIJ i B«o«anaaalfon«al«», i-ohloro-5- (2, 3-
dlbydro-l-bydroiy-3-oio-11-l*olodol*1-yl)- (9 CI) 16
BBC, Total (10 poatinga lo CHBHUIE) . 17-21
Bipbanyl, chloro (8 CI) | I, l«-Biph»nyl, ohlovo d«eif» (• CI) 22-*i
Ctdilai «7
C«ff«ln» (8 CI) | IH-Purin«-2,6-dion«, 3, 7-dl hydro- l,3,7-tcil«th;l- (9 CI) «8, 29S
C»lcltt« 49, SO
Cblcrd«n« SI
Chlorofoc. (8 Cl)| B«tb«B«, triobloco- (9 CI) S2
Cbio»iu« S3, 5«
Copp»r SS-S9
Crolob«x*o«, 1,2,1,*, S,6-h«Mohloca-, alpha- (8 CI) I CyolobasaB*. l,2,3,*,S,6-kasaakioco-, (1alpha,2alpk«,
3b«ta,«alpba,Sb«ta,6b«ta)- (9 CI) 60-69
Cyolohcsan*, l,2,3,«, S, 6-b«uobloco-, b«ta- (8 CI) I Cyelok«saa«, 1,2, 3,*,S, 6-bataobloco-, (1alpha,2b«ta,
3«lph«,Kb»t«,S«lph«,*b«ta)- (9 CI) 66-76
Cyclobaxaoe, 1,2,3,«,S, i-b«iaohloco-, delta- (8 CI) | Cyolob«iaoa, I,], 3>a,3,6-b«saobloro-, ( lalpba,2alpba,
3alpbi.«b«t«,3alpba,»b«ta)- (4 CI) 79, 80
CyolohaxaD*, l,2,3,4,S,6-haiacaloio-, gaaaa- (6 CI) I Cy«lok«iaa«, 1,2,1, *, 9, 6-b«*aoaloro-, (1alpka,2alpka,
3bata,«alpha,3alpha,6b«ta)- {9 CI) 61-91
DDT, total (lo poatlnga lo CHULIII). 92-106
Dlgoiio (8 CI) | citd-20 (22)-anoH4«, 3-((0-2,6-dld«otj-b«ta-l>-clb0-b«Mpynao«yl-(l-«)-0-.2,6-did«o«y-b«ta-D-
rlbo-b«Kopytano»yl- (l-«)-2,6-41d«oiy-b«ta-0-clbo-h««opynao«7l)oiy)-l2, 14-dikydroiy-, <3b«ta,Sb«ta, I2b«ta|-
(9 CI) 107, 108
Eatradlol (8 CI) » Iitca-1,3,S (10)-tcl«o«-J,17-diOl, (17b«ta|- (9 CX) 296
Ithao*, 1, l-dicbloro-2- (o-obloropkanyl) -2- (p-okloropfc«nyl)- (8 CI) | B«DS«M, 1-chloio-2-(2,2-dlchloco-f- («-
oblocoph«nyl)«tbyl)- (9 CI) 109, MO
Ethina, I, l-dlobloro-2, 2-bla(p-ablocpb«Byl|- (8 CI| j B«BMM, I, I'- (2»2-dlohloro«tkylld«B«) bi«(»-ohlof<»- (9
CI) 111-118
Btbao*, 1, 1, 1-tciobloro-2-(o-chlocopB«ayl)-2-(p-obloropk»yl)- (8 CI) j Muaa*, »-ckloro-2- <2,2,2-trlo»loro- »-
(tt-chloropb«nyD«thyl)- (9 a) 1 19- 125
BtbaM, I, 1, 1-tclobloco-2,2-bi«(p-oklocopb«ayl)- <8CI)j MAMM, I, !•- (2,2,i-trleklor»«thTlid«B«) bi«(»-
ebloro- (9 CI) 126-155
Btbyl«a«, t«tcaobloro- (8 CI) I ItbaiM, tatrachloro- (9 CI) 156
Etbylana, 1, 1-dlcbloco-2- (o-oblocopk«ayl)-2- (p-cklocoph«ayl) - (8 CI) j B«BZ«M, l-8bloto-2-|2,2-diohloco- I- (4-
obloropb«nyl)«tb«nyl(- (9 CI) 157-159
Etbyl«B«, 1. l-dicbloro-2, 2-bia(p-cklotoptMByl) - OCX); BMMBA, 1, 1'-(«icfcloro«tb«BTUd«n«» bla (•-eklovo- (9
CI) 160-190
Floorld* 191, 192
R«xachlocob«DSOl (lo poatlaga ID CRIHLIII) . 193
l*- 1-«tbaaol, alpha- (Mtboiya«tbyl) -2-altto- (8 CI); IB-IaUaxol«- t-«thaaol, alpba-(Mtkoxya*tbyl)-2-
nitco- (9 CI) 297
lodid* 194
Icon 195- 198
L-*»corbic acid 199
L-Ptollo*, l-(3-B«ccapto-2-B«tbyl-l-oropropyl)-, (fl)- 298
Hagnaaina 200, 201
-------
104
.AS Preferred Nase Index
,1ar.qa;.ese 202-204
lercury 205-209
Nethylsulfcne PCB (No postings in CBEHLINE). 210
Hocpbinan-6alpba-ol, 7,8-didehydro-4,5alpha-epoxy-3-Bethoxy-17-iethyl- (SCI); Rorphinan-6-ol, 7,8-didehylro-
4,5-epoxy-3-»ethoxy-17-«ethyl-. (5alpha,6alpha) - (9 CI) 299
Nicotine (8 CI) ; Pyridine. 3- (1-«ethyl-2-pycrolidinyl) -, (S) - (9 CI) 211
p-lcetopbenetidide (SCI); Icetaaide, R-(4-ethoxypbenyl) - (9 CI) 300
Phenol. 2,2'-iethylenebis(3,4,6-trichloro- 212
Polybrominated biphenyls (lo postings in CBEHLIME) . 213-216
Polycblorioated guaterphenyls (lo postings in CBEHLIHE). 217
Pyridoxol (SCI); 3,4-Pyridinediiethanol, S-hydroxy-6-ietbyl- (9 CI) 301
Salicylic acid (8 CI) ; Benzoic add, 2-hydroxy- (9 CI) 302
Salicylic acid, ion (1-) (8 CI) ; Benzoic acid, 2-hydrory-, ion(l-) (9 CI) (Til) 303
Salicylic acid, 5-((p-(2-pyridylsalfa«oyl) phenyl) azo) - (SCI); Banzoic acid, 2-hydroxj-S- ((»- ((2-
pyridinylaaino) sul(onyl) phenyl(azo)- (9 CI) 304
Selenlu. 218-220
Sodiu*, ion (Ba(l»)) 221
Sulfanilaiide, 8 (I) - (3, «-di«ethyl-5-isoxazolyl) - (SCI); Benzenesulf onamide, U-aiino-H-(3,4-diiethyl-5-
isoxazolyl)- (9 CI) 305
Tecbnetiui, isotope of BBSS 99 222
Ibeobroiioe (SCI); IH-Purine-2,6-dione, 3,7-dlhydro-3,7-di»ethrl- (9 CI) 306
Tbeopbylline (8 CI); 1H-Purine-2,6-dione, 3,7-dihydro-1, 3-di«ethyl- (9 CI) 307
Tocopbecol 223
Oracil, 6-jropyl-2-tbio- (8 CI) ; 4( 1H)-Pyri»idinone, 2,3-dihydro-6-propyl-2-thioxo- (9 CI) 224, 308
Valeric acid, 2-propyl- (8 CI); Pentanoic acid, 2-propyl- (9 CI) 225, 309
Vanadiui 226
Zinc 227-230
l-Piperazioeethanol, 4-(3-(2-(trif luoroiethyl)-9H-thioxanthen-9-ylidene) pcopyl-, (Z) - 310
1,2-Propanediol, 3-(2-nitroi«idazol-1-yl)- (SCI); 1,2-Propanediol, 3-(2-nitro-1B-i«idazol-1-yl- (9 CI) 311
1.3,4-Hetheno-1H-cyclobuta (cd)pentaleoe, I, 1a,2,2,3,3a,4,5,5,Sa,5b,6-dodacacblocooctahydro- 231
1,4:5,8-Diwtbanonaphtbalena. 1,2,3,4, 10, 10-hexachloro-1,4,4a,5,8,8a-hexahydro-, endo,exo- (SCI); 1,4:5,8-
Diiethanonapbthalene, 1,2,3,1,10, 10-h«xachloro-1,4,4a, E,8,8a-hexabydro-, (lalpba,4alpha,4abeta,5alpha,
Salpha.Sabeta)- (9 CI) 232-235
1,4:5,S-Oi*ethanonapbtlialene, 1,2,3(4, 10,10-h«xachloro-6,7-epoxy- 1,4,4a,5,6,7,8,8a-octahydro-, endo.exo- (8
CI) ; 2,7:3,6-DiBetbanonaphtb(2,3-b)oxic«ne, 3,tt,5,6,9,9-hexachloro-la,2,2a,3,6,6a,7,7a-octahydro-f (laalpha,
2beta, 2aalpha, 3beta,6beta,6aalpha,7beta,7aalpha) - (9 CI) 236-259
18,19-oinot-17alpha-pregn-4-en-20-yn-3-on*, 13-ethyl-17-hydroxy-, (»-)- (8 CI); 18,19-Dinorpregn-9-en-20-yn-3-
one, l3-etbyl-17-bydcozy-, (17alpha)-(»-)- (9 CI) 312
3-Heptacone, 6-(di««thylaaino)-4,4-diphenyl- 313
4-Iiidazoline-l-cacboxrlic acid, 3-«ethyl-2-thioxo-, ethyl ester (8 CI) ; IH-Iaidazola-1-carboxylic acid, 2,3-
dibydro-3-*etbyl-2-thioxo-. ethyl aster (9 CI) 310
4-Thia-l-azabicyclo(3.2.0)heptane-2-carboxylic add, 6-(2-a»ino-2-(p-hydroxyphenyl)acetaiido) -3,3-di«ethyl-7-
oxo-, 0- (8 CI); 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((a«ino(4-
hydroiyphenyl)acetyl)a«ino)-3,>diiethyl-7-oxo, (2S- (2alpha,5alpha,6bata (S*|)) - (9 CI) 315
9,7-Sethano-lB-indene, 1,2,3,4, 5,6, 7,8, 8-nonachloro-2,3,3a, 4, 7, 7a-hexahydro-, (1 alpha,2beta,3alpba,3aalphi,
4teta.7beta,7aalpha)- 260-265
4,7-Betbanoindan, 1,2,4,5,6,7,8,8-octachloro-l,2-epoxy-3a,4,7,7a-tetrahydro- (6 CI); 2,5-Hethano-2H-inden3 (I,
2-b)oxirene, 1a,2,3,4,5,6a,7,7-octachloro-1a, 1b,5,5a,6,6a-hexahydro- (9 CI) 266-274
4,7-Betbanoindan, 1,4,5,6,7,8,8-heptachloro-2,3-epoxy-3a,4,7,7a-tetrahydro- (8 CI); 2,5-!iethano-2B-indeno( 1,2-
bloxicene, 2,3,4,5.6, 7,7-heptachloro-1a, 1b,5,5a,6,6a-hexabydco- (9 CI) 275-290
-,7-fletbanciodene, 1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro- (SCI): 4.7-Hethaoo-IB-indene, 1,4,5,6,7,8,
8-heptachlcro-3a.a,7,7a-tetrahydro- (9 CI) 291, 292
-------
105
CAS Preferred yaie Index
5-Thia- 1-a zabicyclo(d.2.0) oct-2-ene-2-carboxylic acid. 3- (((5-sethyl- 1,3, »-thiadiazol-2-yl| thio) lethyl) -8-oxo-
7-(2-(1H-tetrazol-1-yl)acetaiido)- (8 CI) ; 5-Thia-l-azabicyclo(H.2.0) oct-2-ene-2-carboxylic acid. 3-(((5-
•ethyl-1,3,«-thiadiazol-2-yl) thio) •ethyl)-8-oxo-7-((1H-tetcazol-1-ylacetyl) asino)-. (6H-tran»)- (9 CI) 293
5-Thia-1-azabicyclo(«.2.0)oct-2-ene-2-cacboxylic acid, 3- ((aotyloxy) Mthyl)-7- ( ( (2-a»ino-«-
thiazolyl) (•etboxyiiino)acetyl)aaino)-8-oxo -, (6B-traos>- 316
5-Thia-l-azabicyclo(a.2.0)oct-2-ena-2-carboxylic acid, 3- (hydroxymethyl)-8-oxo-7-(2-(2-thienyl| aceta»ido)-
ac«tate (ester) (8CI); 5-Thia-J-azabicyclo(a.2.0)oct-2-ene-2-carboxylic acid, 3-( (acetyloxy) •ethyl)-8-axo-
7-((2-thienylacetyl)a«ino)-, (6B-trans>- (9 CI) 317
5-Thia-1-azabicyclo(«.2.0)oct-2-ene-2-carboxylic acid, 3- (hydcoxy«ethyl)-8-oxo-7-(2- (i»-pyridylthio» acetaiido) -
, acetate (ester) (8 CI) ; 5-Thia- l-azabicyclo(tt.2.0)oct-2-ene-2-cacboxylic acid, 3-((acetyloxy) aethyl) -8-
oxo-7-(( (0-pycidinylthio|acetyl)aiiDO)-, (SB-trans) - (9 CI) 318
5-Thia-t-azabicyclo(«.2.0)oct-2-eoe-2-carboxylic acid, 7-((a»ino(4-hydrojcyphenyl)acetyl)a«ino)-3-«ethyl-8-oxo-
, (6B-(6alpha,7beta(B*)»- 319
5-Thia-l-aiabicyclo(«l.2.0)oct-2-ene-2-carboxylic acid, 7-(2-a«ino-2-phenylac«ta»ido)-3-«ethyl-8-oxo-, D- (8
CI) ; 5-Thia-l-azabicyclo(tt.2.0)oct-2-ene-2-carboxylic acid, 7-((««inophenylacetyl) aiino)-3-Bethyl-8-oxo-,
(6B-(6alpha,7beta(B«)))- (9 CI) 320
SB-Oibenz (b,f)azepine-5-cacboxaiide 321
-------
107
CAS aegiatrj Nuibec Index
I02U-57-3 275-290
103-90-2 294
108-90-7 2
11097-69-1 I
118-70-1 0-10
127-18-0 156
127-69-5 305
12769-03-6 51
1336-36-3 22-«6
13551-87-6 297
13551-92-3 311
1006-66-2 223
10133-76-7 222
153-61-7 317
15686-71-2 320
16980-08-8 191, 192
17301-25-2 221
20061-50-5 199
20830-75-5 107, 108
21593-23-7 318
22232-50-8 310
2385-85-5 231
25321-22-6 3
25953-19-9 293
26787-78-0 315
26880-08-8 266-270
298-06-0 321
309-00-2 232-235
319-80-6 60-65
319-85-7 66-78
319-86-8 79, 80
3020-82-6 157-159
39765-80-5 260-265
50-28-2 296
50-29-3 92-106, 126-155
50-81-7 199
50370-12-2 319
51-52-5 220, 308
53-19-0 109, 110
53772-82-0 310
50-11-5 211
58-08-2 08, 295
58-55-9 307
58-89-9 19-21, 81-91
599-79-1 300
60-57-1 236-259
608-93-5 IS
60806-21-1 316
62-04-2 300
62571-86-2 298
63-36-5 303
65-23-6 301
6533-00-2 312
67-66-3 52
69-72-7 302
70-30-0 212
72-50-8 111-118
72-55-9 160-190
7039-89-6 195-198
7039-95-0 200, 201
7039-96-5 202-200
7039-97-6 205-209
7000-03-9 07
7000-07-3 53, 50
7000-50-8 55-59
7000-62-2 226
7000-66-6 227-230
7000-70-2 09. 50
76-00-8 291, 292
76-57-3 299
76-99-3 313
77-36-1 16
7782-09-2 218-220
789-02-6 119- 125
83-67-0 306
99-66-1 225, 309
-------
109
Chelical Synonya Index
(»-)-Horgeitrel 312
(-)-Nicotine 211
Aafc«pta 291, 292
Aalindan 81-91
Aa»€to-extra 126-155
Atenaanil 294
Acaiol 294
Acet-p-phenetidin 300
Acetagesic 291
Acotalgln 294
Acetaiinofen 294
AcataiioopbeD 294
Acetic acid, dipropyl- 225, 309
Acetophenetidin 300
Acetophenetidine 300
Icetophenetio 300
Acigena 212
Adenex 199
AdereiD 301
Afield* 8 1-9 I
Agritan 126-155
Agrocecea 291, 292
Agiocide 81-91
Agrocide III 81-91
Agrocide HP 81-91
Aldocit 232-235
Aldrin 232-235
Aldrin Bpoiide 236-259
Alert-Pap 46, 295
Algottopil 294
AlgOTetin 313
Allbri Hataral Copper 55-59
Allercorb 199
AlMdem 212
alpha-Benzene bexachloride 60-65
alpba-BHC 60-65
alpha-Flupenthixol 310
alpha-HCH 60-65
alpha-Hexachlocan 60-65
alpha-Beiachloraoe 60-65
alpba-Bexacblorcyclob«xaoe 60-65
alpha-Bexachlorocyclohaxaoe 60-65
alpba-Lindane 60-65
alpha-Vocgcatcel 312
alpba-1,2,3,4,5,6-Hexachlorcycloh«ian« 60-65
alpha-1,2,3,4,5,6-Hexachlorocyclohexane 60-6S
alpha,alpha-Bis (p-chlocophenyl) -beta,beta, beta-
tcichlorethane 126-155
Alphazole 305
Altcad 296
Airedon 294
AlTlt 55 236-259
Aiadll 294
Aiatio 4-14
A«ei«en«ittel leek 81-91
Aaeisentod 81-91
Alidon 313
Aaidone 313
Alidoxal 305
Aaisia-aottancchatz 3
Aioxicillin 315
Aaoxil 315
Aeoxycillin 315
Anac 110 55-59
Anaflon 294
Anelix 294
•nkilMtin 156
Anticacle 4-14
Antiaal 1 156
Anti»cocbic »ita«in 199
Antiscorbutic »ita«in 199
Apaaid 294
Apaiida 294
APAP 294
Aparaain 81-91
Aphtiria 81-91
Aplidal 81-91
Aqoadiol 296
Arbitex 81-9 I
Arkotine 126-155
Araco iron 195-198
Arochlor 1254 1
Aruood copper 55-59
Ascoltin 199
Ascocbajao 199
ascorbic acid 199
Aacorbutina 199
iacorin 199
Ascorteal 199
ascorvit 199
-------
110
Cbeiical Synonym Index
XI 7 212
Athyroiaxole 314
l7opTrin 304
Azopyrine 304
Azotox H-33 126-155
Azulfidine 304
B 32 212
Ba 2796 194
Batdiol 296
Basolest 314
BEH 81-91
Belt 51
Ben-Hex 81-91
Ben-u-ron 294
Bentox 10 81-91
Benzosalfa 304
beta-Benzene bexachloride 66-78
beta-BBC 66-78
beta-Estradiol 296
beta-BCH 66-78
beta-Hexachlocobenzene 66-78
beta-Hexachlorocyclohexane 66-78
beta-Linda He 66-78
beta-Pyridyl-alpha-H-BethylpyrroUdina 211
beta-1,2,3,4,5,6-Hexachlorocyclohexane 66-78
Bexol 81-91
Bezatin 301
BBC 81-91
BBC. total 17-21
Bickie-iol 294
Bilevon 212
Bipoenyl, chlorinated 22-46
Bis(2-hjdroxi-3,5,6-trichlorophenyl) •ethane 212
Bis (3,5,6-1 rich lor o- 2-hydroxyphenyl) •« thane 212
BI-S 578 319
BLE 1410 315
Bine powder 227-230
Boaan supra 126-155
Bovideool 126-155
BS1 2333 315
Boot-cure 4-14
Bnnt-no-ioce 4-14
C.6. 1 314
C.I. PigieDt Hetal 2 55-59
C.I. 77180 47
C.I. 77400 55-59
C.I. 77805 218-220
C-Quin 199
C-Vl«in 199
Cadaiut 47
Cafeina 48, 295
Caffein 48, 295
Caffeine 48, 295
Cafipel 48, 295
Calciai 49, 50
Calpol 294
Cantan 199
Cantaxin 199
Captopril 298
Carbaiazepen 321
Carbacazepine 321
Carbazepine 321
Carbethoxriethiiazole 314
Carbiaazol 314
Carbiiazole 314
Catarin C 199
CB 313 109, 110
CD-68 51
CDA 101 55-59
CDA 102 55-59
CDA 110 55-59
CDA 122 55-59
Ce-Hi-Lin 199
Ce-Vi-Sol 199
Cebicure 199
Cebion 199
Cebione 199
Cecon 199
Cefadroxil 319
Cefalexin 320
cefalotin 317
Cefaloto 320
Cefaaezin 293
Cefaiezine 293
Cefazolin 293
Cefazoline 293
CeCotaziie 316
Cegiolan 199
Ceglion 199
Celanex 81-91
-------
111
Chelical Sjnooya Index
Celaakan 199
Cello 199
C«nagjl 199
Ceoetone 199
Cepbalexin 320
cepbalosporanic acid 318
Cepbalothin 317
Cepbalotin 317
Cepbapicin 318
Cepbaxolin 293
Cepbazoline 293
Cepotez 320
Ceporexine 320
Ceieoo 199
Cecgona 199
Ceacocbat 199
Cetadol 29«
Cetaaid 199
Ceteaican 199
Ce»alin 199
Cevatine 199
Cevex 199
Cevlain 199
Ce*ltal 199
Cevitaaic acid 199
Cefltaain 199
Cevitan 199
Ce»itez 199
CIZ 293
C6-1283 231
Cbeaonag 305
Cbloditan 109. 110
Cbloditbane 109, 110
Chloc Kil 51
Chlcrdan 51
Chlotdane 51
Cblordane (Technical) 51
Cbloceaene 8 1-9 1
Cblocinated diphenjl 22-46
Cblorobenzcne 2
Cbloroforiic digitalin 107, 108
ChloEOphenotbane 126-155
Cblorotbalidone 16
Chlorphenothan 126-155
Cblocphanotoiaa 126-155
Chlotpbtahlidolone 16
Cblorpbthalidone 16
Cbloctalidone 16
Chloctbalidon 16
Cblocthalidone 16
Cbroaiui 53, 5«
Ciaaio 199
Clpca 199
cia-(Z)-Flopenthizol 310
cl«-Batradiol 296
cU-Plapentbizol 310
cia-Plapeotijcol 310
Citoz 126-155
Claiozyl 315
Clixodyne 294
CloCenotan 126-155
Clofenotane 126-155
Co-op Baza 4-14
Codecbine 81-91
Codeine 299
Coffeine 48, 295
Colascor 199
Colloidal aanganeea 202-204
Coepoand 118 232-235
Compound 497 236-259
Conceain 199
Condicept 299
Capper 55-59
Copper B 1 55-59
Copper ponder S5-59
Cordiozil 107, 108
Corodane 51
Corpageo 296
Cotofili 212
CT 317
CO S3 55-59
CuEP 55-59
CoBPP 55-59
Cutaval 202-204
D-{-)-alpha-laino-p-hrdrozybenzjl penicillin 315
D- (alpba-taino-p-hrdrozrbenzrl) penicillin 315
D-2-*Bino-2-(4-hydrox7phenyl) acetaaidopenicillanic acid
d-3,17beta-Bstcadiol 296
Oavitaaor C 199
-------
112
uhelical Synonya Index
Davoxin IC7. 108
OBH 81-91
DCE 3
DCuPI 55-59
ODD 111-118
DDE 160-190
DDT 126-155
DDT. total 92-106
Decblocane 231
Decblocane Plus 231
Decblorane Plus 515 231
Dechlorane V070 231
Decblorane 515 231
delta-(aeeee)-1,2.3,4,5,6-Hexacblorocyclobexane 79, 80
delta-Benzene bexachlori.de 79, 80
delta-BHC 79, 80
delta-BCH 79, 80
delta-Bexachlorocyclohexane 79, 80
delta-Lindane 79, 80
delta-1.2.3,4,5,6-BexachlOEOCyclohexane 79, 80
Deietbyliiaonidazole 3 11
Deo»al 126-155
Depakine 225, 309
Desiethyltisonidazole 311
Det«ol-Extrakt 81-91
Detox 126-155
Detoxan 126-155
Devoran 81-91
Dial-a-gesic 294
Diaiinon 313
Dibovin 126-155
Dicblocobenzene 3
Dicblorodiphenyl dichlocoetbane 111-118
DichlorodipbeDyltrlchloroethane 126-155
Dicopbaae 126-155
Didakene 156
Dieldrex 236-259
Dieldrio 236-259
Dieliotb 236-259
Dietary ealciu «9, 50
Digacin 107, 108
Digitalis glycoaide 107, 108
Dihydrofolliculac boraone 296
Dihydrofolliculin 296
Dibydcoienfonon 296
Dihydcotheelin 296
Dibydroxyestcin 296
Dildcin 236-259
Dileoe 111-118
Dlienforion 296
Diogyn 296
Diogynets 296
Dipcopylacetic acid 225, 309
Dtcox 29«
Distodin 212
Diurobroaine 306
Dixina 107, 108
dl-lorgestrel 312
Dodat 126-155
Dodecachlorooctahydro-1,3,4-«etheno-2B-
cyclobuta (cd) pentalene 231
Dol Granalo 81-91
Dolophin 313
Dorsaltan larthaaeen 305
Dorytox 236-259
DPI 22S, 309
Drilltox-Spezial Iglnkon 81-91
Dykol 126-155
Dyiadon 294
E 3314 291, 292
B-CU57 55-59
Elixophyllin 307
Elixophylline 307
Elzogra* 293
Eneril 294
BIT 15,152 291, 292
KIT 15.949 232-235
EHT 25.584 275-290
BKT 25.719 231
Ell 7,796 81-91
BIT-1506 126-155
EIT-16225 236-259
Entoioxan 81-91
Bntasil 305
Entasal 305
ZOS1 195-198
Epoxyheptachlor 275-290
Brgenyl 225, 309
Estonate 126-155
Estra-1,3, 5 (10) -triene-3,17-beta-diol 296
-------
113
chelical Synonya Index
3£tra-l.3.5(10)-triene-3, 17-diol. (I7bnta)- 296
E«tra-1,3,5-tciene 296
Eitiol 296
Ectrovite 296
Ethane, I, I. l-tricbloro-2,2-bia(4-cblocophenyl) 126-
Bthyl-3-«ethyl-2-thioimidazoline-1-carboxylate 314
Btbylene tetcachlotlde 156
Exofene 212
Petrilix 294
Febro-Geaic 294
Petrolin 294
Pedal-Do 156
Peieatcal 296
Peiogen 296
Peodon 294
Penidina 300
Peoioa 300
FerroTac E 195-198
Feaia-Bio 212
fB 122-1 312
Finiaol 294
Finlepain 321
Fluoride 191, 192
Flootide loo 191, 192
Fluorine ion (1-) 191, 192
Flux aaag 211
PolllcTclio 296
FOESt-fexen 81-91
Foatril 212
6 11 212
G 32883 321
G 33182 16
Gana benzene bexachloride 81-91
gaaaa-Beozeoe bexachlorlde 81-91
gana-BHC 81-91
gaiaa-HCH 8 1-9 I
gaiia-Hexachlocaa 81-91
gaiia-Hezachlocaoe 81-91
gaaaa-Hezachlocobenzene 81-91
g ana-Bezachlorocrclohexane 81-91
gaaaa-Liodane 81-91
ga»a-1,2,3,ll,S>6-BezacblocoCTClobezane 81-91
Saaiater 81-91
Saicphen 212
Gaaophene 212
Gantciain 305
Gantrisona 305
Gantrosan 305
GC 1283 231
Geigy 32883 321
Gecaa-Hedica 212
Geaafid 126-155
Geaarol 126-155
Gesane 81-91
Ginoaedol 296
GPKh 291, 292
Guacaoine 48, 295
Gynceatcyl 296
Gynecgon 296
HCB 4-14
HCC 81-91
HCCH 8 1-91
HCB 275-290
BCH 81-91
BCB, total 17-21
Heclotoz 81-91
Bedez 294
HEOD 236-259
Bepta 291, 292
Heptachlor 291, 292
Heptachloc epozide 275-290
Beptachlocaae 291, 292
Beptadone 313
Heptanon [pharmaceutical] 313
Besa 81-91
Bexablam 212
Bexachloran 81-9 I
Bexachlocaae 81-91
Bexachlorobeozene 4-14
Bexachlocobenzol 193
flexachlorocyclopentadiene diaer 231
Bexachlorofea 212
BaxacUorophen 212
Bexachlocopbene 212
Bexafen 212
Bex BT era 81-91
Bexicida 81-91
Baxophene 212
Bexosan 212
-------
114
C helical Synooyi Index
Jexyclan 81-91
HGI 81-91
HBCB 232-235
Hoacclan 294
Uoiolle's digitalin 107, 108
Hortex 81-91
Hnngaria L 7 81-91
Hybrln 199
Hydriodlc acid, ion(l-) 194
Hydrofluoric acid, ion (1-) 191, 192
Hyqroton 16
IDO-C 199
Igroton 16
Illoxol 236-259
Inaectlack 236-259
Intox 51
Intox [insecticide] 51
Iodide anicn 199
Iodide ion 19«
Iodide(1-) 194
Iodide-127 194
Iodide, ioo (1(1-)) 194
Iron 195-198
lEoien 16
Isoxaiin 305
I»oran 126-155
Jacotin 81-91
Julie's carbon chloride 4-14
Kafar copper 55-59
Kallin 300
Karbaaazepin 321
Reflex 320
Keforla 320
Retalgin 313
Kottein 48, 295
Kokotine 81-91
Kcibi-llbertan 236-259
Kortofil 232-235
Knell 81-91
Kypchlor 51
L-(«)-iscorbic »cid 199
L-Lyxoascorbic acid 199
L-Iicotine 211
L-threo-Bex-2-enonic acid 199
L-Xyloascorbic acid 199
L-3-Ketothreohexuronic acid 199
Laadiol 296
Lanicor 107, 108
Laaicordio 107, 108
Lanophyllin 307
Lanoxin 107, 108
Larixin 320
Laroacorbine 199
Laiaacorb 199
Lendine 81-91
Lentox 81-91
Lastaap 294
Laxibiotico 320
Lidanal 81-91
Lilly 66873 320
Lindane 81-91
Lindatox 81-91
Lindas 81-91
Lindomp 81-91
Lintox 81-91
Lin*nt 81-91
Ligaagesic 294
Llgni-C«a 199
Lignophylline 307
Loba 195-198
Lonacid 294
Lorexane 81-91
Lysodren 109, 110
Lyteca 294
Lyteca syrap 294
H t 55-59
H 3 55-59
H 4 55-59
Haccodiol 296
Badlexin 320
Hagneaiai 200. 201
Manganese 202-204
Hateina 48, 295
HCB 2
Recodin 313
Hercury 205-209
Sethadone 313
HethylBorphine 299
Hethylsolrone PCB 210
Bethyltheobrosine 46, 295
-------
115
Cbeiical Sjnonya Index
.161700 111-118
Hillol 49 81-91
Hirex 231
Biaonidazole 297
Nitotan 109, 110
Nitctane 109, 110
Honocblorotenzene 2
Honovar 312
Morphine aonoaethyl ether 299
!forphine-3-aethyl ethec 299
Both Snob D 236-259
Bott-Bx 3
Bottenacbntzilttel Evau P 3
Haxycol 81-91
HDltin 299
Hutoxan 126-155
HI [copper] 55-59
B2 [copper] 55-59
H3 [copper] 55-59
B3S 55-59
H31 55-59
B« [copper] 55-59
H (1)-(3,4-EiaethTl-5-isoxazolTl) salfanilaaide 305
H-(H-Hydroxyphanyl) acetaaide 294
K-lcetrl-p-aainophenol 294
N-*cetTl-p-phenetidine 300
R-acetyl-4-aBinopbenol 294
n-Dipropylacetlc add 225,- 309
•abac 212
• m 294
lapafen 294
• m? 294
•apcinol 294
Rattioran 16
Heazolin 305
Keia 156
Heo-scabicidol 81-91
Heo-Tbyreo>tat 314
Neocid 126-155
Veocidol 126-155
Heolexioa 320
Neoaercazole 314
Seoaept V 212
Neoxazol 305
Neurotol 321
Nexen F9 81-91
•exit 81-91
•exit-stark 81-91
•exol-B 81-91
licochloran 81-91
licotlne 211
to Boot 4-14
•o Bant Liquid 4-14
•o Bant 40 4-14
•o Bant 80 4-14
Ho-Doz 48, 295
Hobedon 294
•ordicol 296
•orgeatrel 312
•orilgan-S 305
ISC 261036 311
•SC 261037 297
•SC-38721 109, 110
o-Hydroxybenzoate 303
o-Bydroxybenzotc acid 302
o,p'-DDD 109, 110
o,p*-DDB 157-159
0,p'-ODT 119-125
Orp'-Dichlorodiphenyldichloroethane 109, 110
0,p'-TDE 109, 110
Octa-Klor 51
Octachlor epoxide 266-274
Octalene 232-235
Octalox 236-259
Oestergon 296
Oestra-l,3,5(IO)-triene-3, nbeta-diol 296
Oestradiol 296
Oestroglandol 296
OFBC Co 55-59
Oanitox 81-91
Optiphyllin 307
Oradil 16
Oradziak 81-91
Oraboraon 296
Orasterol 296
Ovastevol 296
Orex [tablets] 296
OTOcyclin 296
OTOcylin 296
Owadziak 81-91
-------
116
Chttical Syoonya Index
Oxjchlordac 266-274
Oxychlordaoe 266-274
p-Ucetylaiioo) phenol 29a
p-AcetaaidOFheool 294
p-Ethoxyacetaailide Pertonal 300
p-Hydroxyacetanilide 294
p-Bydroxyaapicillio 315
p.F'-DDD 111-118
p.F'-DDE 160-190
p.p'-DDT 126-155
p,p'-Dichlorodiphenyl-2,2-dichloro»thyl«n« 111-118
p.p'-Dichlorodiphenyldichloroethan* 111-118
p,p'-Dichlorodiphenyldichloroethylene 160-190
P.p'-Dichlorodiphenyltrichloroethana 126-155
p,F'-TDE 111-118
Paecao 294
Panadol 294
Pancid 305
Facets 294
Paiacetaaol 294
Paxacetaaole 294
Parachlorocidui 126-155
ParXophyllin 307
Patiol 29«
PEE 213-216
PCE 22-46
PCS 1254 1
PEB1 126-155
Pedraczak 61-91
Pedric 294
Pentachlorin 126-155
Peotachlorobenzene 15
PcBtachlorophenyl chloride 4-14
Penticidui 126-155
Perchloretbylene 156
Pccchlocobeozene 4-1*
Percblocodiboiocabane 231
Perchlocoethylene 156
Perchlocopentacyclo(5.2. 1.0(2,6) .0(3.9) .0(5,8)) decane
231
Perchloropentacyclodecace 231
Perclene 156
Perilaocide 191, 192
Perlatanol 296
PetSec 156
Pflanzol 81-91
Phenacetin 300
Phenacetlne 300
Phenadone 313
Phenazetln 300
Phendon 294
Phenedina 300
Phenidin 300
Pbenln 300
Phenol-2-carboxyllc acid 302
Phanyl chloride 2
pBiooBez 212
Phthalaiodine 16
Phthalaiadiae 16
Phyaeptone 313
PiriTitol 301
PlanaTit C 199
Polaaidona 313
Polybcoainated biphenyls 213-216
Polyehlorinated qoaterphenyla 217
Polyiodide 194
Praral 49, 50
Priaofol 296
Pr oca ail 224, 308
Profoliol 296
Progynon 296
Progyooa-DB 296
Propacil 224, 308
Propycil 224, 308
Propyl-Ihioriat 224, 308
Propyl-Tbyracil 224, 308
Propylthiorit 224, 308
Propylthiooracil 224, 308
Pcoacorbin 199
Prothiucil 224, 308
Prothiorone 224, 308
Pcothycil 224, 308
Prothyran 224, 308
Protioral 224, 308
Pseadotheophylline 307
Paoriacid-S-Stift 302
PTO 224, 308
PTO [ tbyreostaUc ] 224, 308
Pyridoxin 301
Pyridorine 301
-------
117
Cbeiical syDonya Index
PyEinazine 294
PZb-IH3 195-198
PZb-2 195-198
PZhlHI 195-198
PZb2H 195-198
PZb2HI 195-198
PZb2H2 195-198
PZh3 195-198
PZh3H 195-198
PZbOH 195-198
Quellada 81-91
Quicksilver 205-209
B 20 52
B 20 [refrigerant] 52
Baney copper 55-59
Bed Shield 236-259
Bedoxon 199
Befreah'n 48, 295
Benon 16
Beoosalfan 305
Betardec 8 302
Beapicin 304
Bbodiaeblor 291, 292
Bhotbane 111-118
Bihena 199
Bito«ept 212
Bo 5-9963 311
BO 7-0582 297
Botaaott 3
BoagoxiD 107, 108
Boxoaul tablets 305
Butranex 302
S 6437 320
SalazopyEidin 304
SalazopyEio 304
SalazOBUlfapyridio 304
SalazosultapyEidioe 304
Salicylat* 303
Salicylate anion 303
Sallc'ylat* ion 303
Salicylazoaalf'apyridine 304
Salicylic acid 302
Salicylic acid colloidon 302
Sali*olf 304
Salonil 302
Salnretin 16
Saag-ga»a 81-91
Sanocide 4-14
Santhaose 306
SC 15090 306
ScocbD-C 199
SO 2794 232-235
SD 3417 236-259
SecoEbat* 199
Seedcin 232-235
Seleaina 218-220
Sencepbalin 320
Septisol 212
Septofen 212
SB 70850 312
Sh 850 312
Snieciotox 4-14
Sodioa («a(1*)) 221
Sodiaa (1+) 221
Sodiai cation 221
Sodioa ion 221
sodiaa ion (la(UM 221
Sodioi lon(U) 221
Sodina(U) ion 221
Solo* in 307
Soaol 305
Soxisol 305
Soxo 305
Soxoiide 305
Spritz-Bapidin 81-91
Spcaahpflanzol 81-91
SQ 14225 298
SB 1354 297
SB 1530 311
SBI 1354 297
Stansin 305
Steral 212
Stecaskin 212
Stia 48, 295
Stceunex 81-91
Salbio 305
SulfadiMthyliBoxacol* 305
Snlfafurazol 305
Snlfafatazole 305
Salfagan 305
-------
118
Cheiical 5700071 Index
Sulfaisoxazole 305
Sulfalar 305
Snlfasalazio 30a
Sulfasalazine 304
Sulfasol 305
Sulfazin 305
Sulfisoxascle 305
sulfiaoxazol 305
Salfiaoxazcle 305
Sulfisoxazole dialaaine 305
Sglfoxol 305
Sulphafurazole 305
Sulphasalazine 304
Solsoxin 305
Sorgi-Cen 212
Sarcfene 212
SOI B-2 195-198
Syndiol 296
Tatalgin 294
Tafidex 126-155
Tap 65 81-91
Tatuzinho 232-235
TOE 111-118
Technetiu«-99 222
Technical Chlocdao« 51
Tegietal 321
Tegretol 321
Teltleo 156
Tealo 294
Teipaoal 294
Teipra 294
TecbEOlin 306
Teofyllaaiii 307
Tecaaeptlc 212
Tetlitoz 236-259
Teatascocbic 199
Tetracap 156
Tetcachloretbylene 156
Tetracblorodiphenyl ethane 111-118
Tetrachloccethene 156
Tetrachlorcothylene 156
Tetiaquer 156
Tetcaleno 156
Tetiopil 156
Theel tabl. 307
Theelin. dihydro- 296
Thein 48, 295
Theine 48, 295
Theocin 307
Theofol 307
Theogcad 307
Theolaic 307
Theolix 307
Theophyllin 307
Theophylline 307
Theosalrose 306
Theoatene 306
Thesal 306
Thlaaio 305
thiacagyl 224, 308
Thyraostat II 224. 308
Tipala 232-235
Tocopherol 223
Toxicblot 51
Tralgon 294
tcans-lonachloc 260-265
Tti-6 81-91
Trichlorobis(4«-chlotophenyl) ethane 126-155
Tcichlocofoc* 52
Tcichlocoiethane 52
Trichlocophene 212
Tassapap 294
Tylenol 294
Tyrazol 314
Dnexaa-Koeder 51
Onisalf 305
Orittialn 305
T-Sol 305
Yaladol 294
Valgeaic 294
Talpcoic acid 225, 309
Tanadini 226
TanadiQB-51 226
Telaicol 104 291, 292
Telsicol 1068 51
Telaicol 53-CS-17 275-290
Ticelat 199
Ticin 199
Tiforcit 199
Tiscorin 199
-------
119
Cbeiical Synonya Index
vitace 199
ritacee 199
fltaciiin 199
Vitacin 199
Vitaain B-6 301
ntaain C 199
?itaaiain 199
Vitaacotbol 199
Vltoo 61-91
By 3707 312
litix 199
XylcascoEbic acid, L- 199
Zaibeail 16
Zccdaoe 126-155
Zinc 227-230
1- (2-HydEoiy-3-aethoxypEOpyl)-2-nitroiaidazole 297
l-(2-Iitro-1-iaidazolyl)-3-»ethoxy-2-propanol 297
l-Ethoxycarbonyl-3-aathyl-2-thio-4-iaidazolin« 31*
I-Keto-3-(3'-suitaayl-4«-chloEophenyl)-3-
hydroxyiaciDdoline 16
l-aethyl-2- (3-pyridyl)pyrrolidine 211
l-Hethyl-3-carb«thoxy-2-thioglyoxalona 31*
l-oxo-3- (3-anlf aByl-4-chlOEOphanyl) -3-
hydEoxyiaciDdoline 16
1,1-Bia (p-cfaloEophenyl) -2,2-dichloro«thane 111-118
1,1-Bia(p-chloEophenyl)-2,2,2-trichloroethane 126-155
1,1-Bis (a-chlorophenyl) -2,2-dichloEoethane 111-118
1,1-DichlOEO-2- (o-chlOEOphanyl) -2- (p-
cblOEOphenyl) ethylana 157-159
1,1-Dichloro-2,2-bia (p-chlocophenyl) ethan* 111-118
l,1-DichlOEO-2,2-biB(p-chlorophenyl)ethylene 160-190
1,l-Dichloro-2,2-bia(4-chloEOphenyl)ethan* 111-118
1,1-Dichloro-2,2-di(p-chlorophenyl)ethyl«na 160-190
1,1,1-Trichloro-2,2-bis (p-chloroph«nyl) ethaoa 126-155
1, 1,1-Trichloco-2,2-bis («,»'-dichlorodiphenyl) ethane
126-155
1,1.2.2-T«trachioroethylen« 156
1,2,3,U,5-pentachlorobeoxene 15
1,2,3,4,5,6-Bexachlorocyclohezane 81-91
1,2,4,5,6,7,8,8-Octachloco-2,3,3a,»,7,7a-hexahydro-9,7-
•etbanoiDdeDe 51
1,2,»,5,6,7,8,8-Octachloro-3a,4,7,7a-tetrahydro-«,7-
•etbaooindao 51
1,2,4,5,6,7,8,8-Octachloro-«,7-aethane-3a,«,7,7a-
tetcafaydcoindane 51
l,3-Cyclop«otadiene, 1,2,3,4,5,5-hexacbloro-, diaec
231
1,3-DiBetbylxantbine 307
l,3,7-Tciaethyl-2,6-dioxopaclne 48. 295
1.3.7-Tciietbylxaothine 48. 295
17b«ta-E8tcadiol 296
I7b«ta-00atcadiol 296
1721 Gold 55-59
2- (2-Chlocophenyl) -2- (4-cblocopheoyl) - I, I-
dlchloroethane 109, 110
2- (2-chlorophenyl) -2- (4-chlorophenyl) - I, I-
dichloroethylene 157-159
2- (2-cblorpbaoyl) -2- (4-chlorophenyl) -1,1.1-
tcichlocoetbane 119-125
2-BydEOzybanzoic acid 302
2-Propylp«ntanoic acid 225, 309
2-PEOpylval«tic acid 225, 309
2-thio-4-oxo-6-pEOpTl-1,3-pyri«idine 224, 308
2-thio-6-pEOpyl-1,3-pyEl«idin-4-one 224, 308
2-2-bis (2-chlorophenyl-»-chlorophenyl) -1,1-
dichlocoathana 109, 110
2,2-Bis(p-chloEop henyl) -1,1,1-trichlocoethane 126-155
2,2-Bis(4-chlorophenyl) -1.1-dichloroetbane 111-118
2,2-BlB(4-chlOEophanyl)-1,1-dicbloEoathylane 160-190
2,2'-0ihydroxy-3,3*,5,5*,6,6»-baxachloEodiphenyliethane
212
2,21-Dihydroxy-3,5,6,3',5',6<-
tatEachlorodiphanylaathana 212
2,21-aethylenebis(3,4,6-trichlocophenol) 212
2,2t,3,3>,5,5<-Hexachloco-6,6«-dlhydcoxydiphenTl»ethar.e
212
2,4'-ODT 119-125
2,4'-Dichlorodiphenyldichloroethane 109, 110
3- (I-Hethylpyrollidi.no) pyridine 211
3- (2-Iitcoiaidazol-1-yl)-l,2-propanediol 311
3- (•• -cblOEO-3»-solf aaoyl-phenyl) -3-
hydEoxyphthali«idine 16
3-Carbethoxyaaccapto-l-aethyliiidazole 314
3-Carbethoiythio-l-aethylglyoxaline 314
3-Casbe Aoxythio- 1-aethy liainiaxola 314
3-Chlorochlocdene 291, 292
3-HjdEoxy-3-(4-cbloEo-3-sul£aaylphenyl) phthaliaidine
16
3-Oxo-L-gnlo£uranolactone 199
3,17-Bpidihydcoxyeatratriene 296
3,17beta-DlhydEoxyestra-1,3,5 (lO)-triene 296
3,17bata-Dihydroxye»tra-1,3,5-triene 296
3.I7beta-Estradiol 296
3,4-Diaethyl-S-sulfanilaaidoisoxatole 305
3,4-Diiathyl-5-salfODaaidoiaoxazole 305
3,7-Di«athylxanthine 306
3keto-L-Gulofaranolactone 199
4-tcetaaidophenol 294
-------
120
Cheaical SJDCDT* Index
U-Acetaaincphenol 2S4
i«-£thoxyacetanilid« 300
4-fieptanecarboxylic acid 225, 309
H-Hydroxyacetanilide 29U
i.H'-DDD 111-118
»,»'-DDE 160-190
i4,»'-DichlorodiphenTltrichloroethane 126-155
H'-Ethoxyacetanilide 300
H'-Hydroxyacetanilide 294
5-(p-(2-Pyridylauieaioyl)pbfli>llazo) salicylic acid 304
5- (p-(2-Pyiidyl«ulfa«yl)ph«nylaio) salicylic acid 304
5- (p-ASinobenzenesulfonasido)-3,4-dii«thyliaoxazole
305
5- (p-A«inobenzena8QlphonaBido) -3,«-dia«thrlisoxaiol«
305
5- (1-iainoFhenylaolf onaaido) -3,«-di»«thylisoiaxol« 305
5-Catbaaoyl-5B-dibenz(b,f)azepin« 321
5-Salfanila»ido-3,«-diaethylisoiazol« 305
6- (D- (-) -p-Bydtoiy-alpha-a«inobenzjl) paoicilllo 3 IS
6-n-Propyl-2-thioaracil 224, 308
6-n-Pcopylthioucacil 224, 308
6-Propyl-2-tbio-2,»(1H,3H)pyri»idinadion« 224, 308
6-Propyl-2-thioaracil 224, 308
6-Propyl«tbiouracil 224, 308
666 81-91
7- (-1- (IB) -t«trazolylaceta«ido) -3-[ 2-(5-Mthyl-1,3,4-
tbiadiazclyl) thioaethyl )-d«lta (3) -caphai-4-carbozylic
acid 293
7-(C-alpba-
aiiDOfheoylacetaiido) dasacatoiycapbalospocacic acid
320
7- (D-2-a«ino-2-phenylaceta»ido) -3-»«thyl-d«lta (3) -
ccpbei-4-caiboxylic acid 320
7- (Thiophere-2-acetaiido)capbalo8porio 317
7-(2-(2-TbieByl)acetylaiido)c«pbalospocaoic acid 317
7-(2-(»-pyridylthio) acetaaido)- 318
7-(2-(»-Pyridylthio)ac«taBido)c«ptaloapocanic acid 318
7-(2-Thienylacctaiido)cepbalOBporaaic acid 317
-------
122
Kajvord Index
AOOLISCERTS 198, 199
AUDITS 2, 3, 9.
37, 39-42, 45,
59, 76. 86, 91
118, 139-141.
174, 176, 178,
192. 198. 199.
217, 220, 230,
209, 253. 256,
284. 285, 287,
302. 303. 305,
315-320
11, 20, 21, 31-34,
47, 48, 51, 52.
, 106-108, 115.
143, 148, 155, 156,
179, 184, 190.
204, 213, 215,
233, 235, 248,
263. 269, 271,
292-295, 297-300,
309, 311, 312,
AGZ 10, 11, 20, 26, 35, 38, 40,
83. 87, 97, 101. 102, 110, 113,
121, 133. 142, 143, 158, 168.
177, 178, 198. 199, 234, 250,
253, 263, 271, 279, 287
AGBICULTUHI 19, 51, 86, 100, 115,
141, 176, 233, 247, 248, 251,
283. 284, 292
US POLLUTION 29, 251
AL1SK1 205
ALDBIN 38. 87, 102, 142, 177, 234
ANALGESICS 294, 295, 299, 300,
302, 303
AIZBIA 198
AIIBU POPOL1TIOBS 213, 214
ANTIBIOTICS 293. 315-320
ANTICONVULSABTS 225, 309
ANTIBTPERTENSIVE AGEITS 298
ANTIPYHBTICS 294, 303
AEIZOIA 218
AOSTBALIA 14, 108, 153. 188, 259
AUSTRIA 175
AOICIOHIC DRUGS 307
AOTOPSIES 9. 10, 31, 35. 37. 101.
140. 217, 250
BF.NZENES 2, 3, 52, 156, 179
BXOACCUaOLATXON 1, 6, 8, IS, 21,
22, 25, 32, 44, 46, 54. 62. 67.
72. 76-78, 81, 91-94, 103-106,
109, 111. 114, 118, 119. 126.
127, 130, 138, 139, 145, 148,
ISO, 151, 154, 155. 157. 160.
161, 165, 173, 174, 181. 184-186,
189, 190, 198, 208, 213. 215.
235-237. 240, 251, 256, 257, 260,
264-266, 273-277. 290. 305
BIPBBNTL CCHPOOIDS 4. 7, 22. 24.
27, 28. 42, 45, 60, 66, 70. 71,
78, 81, 62, 92-94. 104, 109. Ill,
119* 123, 126, 129, 136. 137,
151. 157, 160. 163, 171, 172,
186. 216. 236, 239, 245, 246,
257, 262, 265, 268, 274. 275.
282, 290
BBOHINATED HTDBOCABBONS 213
BBOHXIB ORGANIC COMPOUNDS 213
B01GABXA 175
CALIFORNIA 139. 174. 213
CANADA 1, 7, 10, 13, 26, 35, 38,
41, 43, 48, 6U, 71, 74, 87, 89,
101, 102, 107, 116. 123. 124.
127, 137. 142, 146, 161. 172,
177, 182, 231, 234, 246, 250,
251, 254. 262, 268. 282, 288
CABCINOGEN 29
CABCIIOHAS 22, 81, 92-94, 109,
111, 119, 126, 157. 160, 236.
275, 297, 311
CARDIOVASCULAR DISEASES 107
CASE HISTORIES 107
CBITBAL IEBTODS STSTBH DISEASES
309
CHBBOTBBBAPI 297, 311
CHILDREN 37, 198, 199, 213, 217
CBLOBXRATBD HIDHOCAHBOIS 1-3, 8,
9, 11. 15. 17, 20, 22. 26, 31,
40, 52, 61, 62, 68, 69. 72. 78,
79, 81, 83. 84. 92-97. 99, 104,
109-114, 119-122, 126. 127, 131-
134, 138, 140, 143, 149, 151,
156-161, 166-169, 173, 178, 179.
186, 193, 212, 231, 232, 236,
241-243, 253, 257. 261. 263. 265.
267, 271, 274, 275. 278-280. 287,
290
CBLOBIIE OBGABXC COBPOOIDS I, 4,
7, 8, 10, 15-19. 22-24, 27. 28.
35, 37-39, 42, 45, 51. 60-62, 66,
68-72, 79, 81. 82. 84-87, 92-96,
99-102, 109, 111. 112. 114. 115.
119, 120, 122, 123. 126, 127,
129, 131. 132, 134-138, 141, 142,
157. 159-161. 163, 166, 167, 169-
173, 175-177. 193. 210. 217. 232-
234, 236. 239, 241-250, 261, 262,
267-269, 275, 278, 280-285, 291,
292
CBLOBOBEBZEIBS 2-5, 8, 10, 15, 24,
35, 52, 60, 62, 66, 72, 82, 101,
114, 129, 138, 156, 163, 164,
173, 179, 239, 250
COLOBADO 33, 218
COBPABATIVB EVALUATIONS 9. 12, 13,
18, 31, 37, 43, 48, S3, 57, 64,
65, 74. 75. 85, 89. 90. 116. 117,
124. 125. 135. 140. 146. 14T.
170, 182, 183, 201, 217, 223,
229, 244, 249. 254, 255, 269,
272, 281, 285, 288, 289, 291,
297, 311, 312
CONNECTICUT 218
CBOP DDSIIBG 19, 100, 247, 283
CZECHOSLOVAKIA 63, 73, 80, 88,
144, 180
DE1BABK 224
DIETS 11, 20, 40, 47. 50. 54. 55.
59. 143, 178, 195, 198, 199, 204,
205. 207. 209, 220, 223, 227,
230, 253, 263, 271. 287, 301
DISEASES 37, 217
DIOBETICS 16, 307
DRIIKING RATBB 208, 251
DBOG TBEBAPI 48, 107, 108, 225,
293, 294, 297, 298. 304. 308-311,
DRUG THEBAPT 313, 314
DBUGS 16, 48, 107, 108, 192. 199,
211. 212, 224, 225. 293-295. 297-
300, 302-311, 313-321
EL SALVADOR 19. 100. 247, 283
FABBS 213
FATS 41, 63, 73, 80, 88, 1U4. 180,
231
FECES 226
FETUS 42, 45, 47. 58, 59, 129,
162, 203, 204, 207-209, 219, 225.
230, 238, 309
FINLAND 53, 54
FIBE BETABDANTS 32, 213-215
FISHES 205
FLDOBIIE COBPODBDS 192
FOOD ADDITIVES 198
FOOD COBTABXNATION 19, 23, 32, 37,
54, 100, 208. 213-215, 217, 247,
25 I, 283
FOODS 32, 47, 59, 95, t 12, 120,
131, 166, 198, 199. 204, 205,
215, 220, 230, 241, 306
FBANCE 48
FUNGICIDES 12
GASTROINTESTINAL SISTER 304
GEORGIA 218
GEBBANT 175
GOATEBALA 19, 100, 149, 247, 283
GDINEA PIGS 199
HABAII 11, 20, 40, 128, 143, 162,
178, 238, 253. 263. 271, 287
HEALTH HAZARDS 12, 29, 34, 37, 39.
175, 217, 224, 296
flEXACHLOBOCYCLOBEXAN 271
BOBHONES 296
ILLINOIS 220
INDIA 21, 57, 91. 106, 118, 155,
175, 190, 201, 229. 235
INDIANA 301
INDUSTRIAL ABBAS 2, 3, 34, 52,
156. 179
INDDSTBIAL CBBBICALS 2, 3, 10, 35,
41. 52, 101. 156, 179. 250
INDUSTRIAL EBISSIONS 2, 3, 52,
156, 179
INFANTS 23, 32, 37, 39, 42, 45,
47, 48, 50, 53, 59. 95, 108. 112,
120. 131, 166, 192. 198, 199,
204, 205, 208, 211, 215, 217,
220, 223, 225, 230. 241, 306
INBALATXON 208
INSECTICIDES 17, 19. 61, 69, 79,
84, 99, 100, 122, 134, 149, 159,
169, 193, 232, 243. 247, 280, 283
-------
123
KejuocJ Index
IOWA 206, 208, 218
IRAQ 208
ISRAEL 26, 83, 97, 110, 113, 121.
133, 158, 168, 175, 279
JAFAR 27, 30, 32, 37, 42, 15, 46,
70, 76, 136, 148, 171, 175, 184.
2C7-209. 215, 217, 2«S. 256, 293
K115AS 305
LACIATIOR 1-3, 8, 11, 15, 17. 20,
30, 32, 39, 40, 44. 46, 49, 52-
56. 61. 62, 68, 69, 72, 76, 77,
79. 84. 56. 99, 107, 114, 122,
127. 132, 134, 138, 139, 143.
148-150, 156, 159. 161, 167, 169,
173, 174, 178, 179, 184, 185,
193. 195. 196, 198-200, 202, 206.
208, 212, 215, 220, 222. 224,
225, 227, 228, 232, 237, 242.
243, 249, 253, 256, 261, 263,
264. 267, 269, 271, 273, 276,
278, 280, 285, 287, 293-296, 298-
306, 308-310, 312-321
LIPIDS 22. 26, 81, 83, 92-94. 97.
109-111, 113. 119, 121. 126, 133,
157, 158, 160, 168. 236, 275, 279
LOOISIARA 2, 3, 52, 156, 179
BEASOBBBBHT METHODS 2, 3, 41, 52.
65, 75, 90, 117, 125, 147, 156,
179, 183, 255, 272, 289, 296
HEIAROHAS 297, 311
SEESTBOATIOH 198, 199
8ZII1L BBTIEDATIOH 208
BBTABOIISB 55, 195, 227, 304
HBTABOLITES 48. 68, 96, 132, 167,
192, 199. 210, 242, 261. 267,
278, 303-305, 309, 321
HBI1L POISORIHG 208
RBTALS 47, 49, 53-59, 191, 194-
198, 200-209, 218-222, 226-230
HETBIL HEHCOBI COBPODRDS 207, 209
S1CBIGAB 34, 39, 214, 216
BIREBALS 55. 195, 227
MISSISSIPPI 44, 65, 68, 75, 77,
78. 90, 96, 104, 117, 125, 132.
147, 150, 151, 167, 183, 185,
186, 237, 242, 255, 257, 261,
264. 265, 267, 272-274, 276. 278,
289, 290
aissooBi ie, as, 135, vro, 218,
244. 281, 291
NORTARA 218
NARCOTICS 295, 299, 300, 302, 313
BECfLASBS 22, 81, 92-94. 109, 111.
119, 126, 157, 160, 175, 236, 275
RETBEBLAHDS 175, 251
IEDBOHOSCOI1B DISEASES 48, 225
REB JERSEY 2, 3, 52, 156, 179
RES MEXICO 208
NEB YORK 192, 218, 313
NEB ZEALAHC 47, 59, 204, 230
BBRBORR 9, 21, 30, 31, 48* 55, 58,
91, 106, 107, 118, 140, 155, 190,
195, 203. 205. 219, 223, 225,
227, 235, 309, 310, 313, 321
ROBTH CABOLIBA 36
HOBBAT 9, 17, 31, 61, 69, 79, 84,
99, 122, 134, 140, 1S9, 169, 193,
232, 243. 280
HOTRITIOHAt DEFICIEKIBS 19, 50,
58, 100, 203, 219. 223, 247, 283
ROIBIIIORAL DISOBDEBS 223
OCCDPATIORAL BAZABDS 175, 210
OHIO 218, 222
OICLAHOHA 218
OBAL COUTHACEPTIVBS 199
ORAL DISEASES 199
OBBGOR 218, 225
OBGAHIC CHLORIRE COHPOORDS 46, 76,
148, 184, 256
PAKISTAB 175
PERRSTLVARIA 2, 3, 52, 55, 98,
156, 179, 195, 218, 227
PESTICIDE HESIDDES 2, 3, 6, 10,
II, 19-21, 25, 35, 40, 44, 52,
67, 77, 91, 100. 101, 106, 118,
130. 143, 150, 155, 156, 165,
176, 179. 185. 190. 235. 237,
240. 247, 250-253, 260, 263. 264,
266. 270, 271, 273, 276, 277,
283, 286, 287
PESTICIDES 1, 4-11, 13-15, 17-20,
22, 24-26, 28, 31, 35, 40, 42-46.
51. 60-69, 71-86, 88-90, 92-101,
103-105, 109-117, 119-135, 137-
141, 143-154, 157-170, 172-176,
178, 180-189, 193, 231-233, 236-
244, 246-251. 253-285, 287-292
PIGS 198
POLAHD 175
POLTBROBIRATBD BIPBERTLS 32, 213-
215
POLICHLOBIHATED BIPBERTLS 1, 4, 6,
7, 9-11, 13, 20, 22. 24-43, 45,
46, 60, 64, 66, 67, 70, 71, 74,
76, 81-83, 87, 89, 92-94, 97,
101, 102, 109-111, 113, 116, 119,
121, 123. 124. 126. 127, 129,
130. 133, 136, 137, 140. 142,
143, 146, 148, 157, 158, 160,
161, 163, 165, 168, 171, 172,
177, 178, 182, 184, 210, 215,
217. 234. 236. 239, 240, 245,
246. 250. 253, 254,. 256, 260,
262, 263, 266, 268, 271, 275.
277. 279, 282, 287, 288
POLICHLOBIRATED QOATEBPHERILS 37.
217
POLTCBLOBIVATED TERPHERILS 7, 28.
71, 123, 137, 172, 246, 262, 268,
282
POPOLATIOB EIPOSORE 10-12, 20. 26,
29, 32, 33, 35, 38, 40, 44, 77.
83, 87, 97. 101-103, 105. 110,
113, 121, 133, 142, 143, 145,
150. 154, 158, 168, 175, 177.
178, 181, 185, 189. 215, 234,
237, 250, 251, 253, 263, 264.
POPOLATIOH EXPOSURE 271, 273, 276,
279, 286, 287
POBTD6AL 152, 187, 259
PBEGRAHCT 16, 30, 107, 198, 199,
205, 208, 304, 309, 310, 313
PBOGESTOGEHS 312
RADIOISOTOPES 198, 193, 222
BATS 198
REVIEW 29. 32, 39. 47, *8, 59,
175, 198, 199, 203, 204, 208,
214, 215, 219, 230, 251
BDEAL ABEAS 8, 12, 15, 33, 38, 51,
57, 62, 72, 86, 87, 102, 11«,
115, 138, 141, 142, 173, 176,
177, 201, 213, 229, 233, 234,
248, 284, 292
BOSSIA 175
SCOTLARD 308, 314
SEX 199
SKIB DISEASES 32, 199, 215
SBOKIBG 38, 87, 98, 102, 142, 177,
199, 211, 234
SOILS 47. 59, 204, 230
SOLVEHTS 2, 3, 52, 156, 179
SOOTH DAKOTA 218
SPAIR 12, 51, 86, 115. 141, 176,
233, 248, 284, 292
STBBOIDS 296
SOLPOBAHIDBS 305
SWEDE! 4, 24, 60, 66, 82, 103,
105, 129, 145, 154, 163, 175,
181, 189, 197, 208, 239, 312
TERRESSEE 208
TEXAS 218
TBEOPBTLLIRES 48
TBACE ELEBERTS 47, 57-59, 197,
201, 203, 204. 219. 229, 230
TRABQOILIZEBS 310
OLTBAYIOLET BADIATIOR 231
ORITED KIRGDOB 50, 58, 191, 194,
203, 219, 221, 251
ORITED STATES 36, 175, 249, 251,
252. 269, 270, 285, 286
OBBAR ABEAS 2, 3, 12, 38. 51, 52,
57, 86, 87, 102, 115, 141. 142,
156, 176. 177. 179. 201. 207,
209, 218. 229, 233, 234, 248,
284, 292
OTAB 218
VEGBTATIOI 47, 59. 204, 230
fITABIRS 223, 301
WATER POLLUTION 29, 251
VEST VIBGIRIA 2, 3, 52, 156, 179
8TOBIRG 218
-------
124
Keyword lades
TOGCSLAVI1 8, IS, 62, 72. 114,
138, 173
-------
125
«n272 -101
REPORT DOCUMENTATION
PAGE
1. REPORT NO.
EPA 560/5-83-009
3. Recipient" • Accession No.
4. Title end Subtitle
Chemicals Identified in Human Breast Milk,
A Literature Search
S. Report Data
October 1983
7. Author^ M. Virginia Cone, Margaret F. Baldauf,
Dennis M. Opresko, and Mary S. Uziel (Data Base)
8. Performing Organization R«pt No.
9. Performing Organization Name end Address
Chemical Effects Information Center
Information Center Complex/Information Division
Oak Ridge National Laboratory
Oak Ridge, Tennessee 37830
10. Pro|ect/T«sk/Wortc Unit No.
11. Contrect(C) or Grent(G) No.
(O EPA/DOE IAG #
(0) DW930139-01-1
12. Sponsoring Organisation Name and Address
U.S. Environmental Protection Agency
Office of Toxic Substances
Exposure Evaluation Division
401 M Street SW, Washington, DC 20460
IX Type of Report A Period Covered
14.
15. Supplementary Note*
16. Abstract (Unite 200 words)
This is a computerized literature search for data on
chemicals identified in human mammary gland, milk, milk fat
and whole milk. It was accomplished for the Office of Toxic
Substances' Exposure Evaluation Division, Environmental Protection
Agency. These data were collected from a comprehensive human
body-burden data base being developed under the direction of the
Environmental Protection Agency and the National Cancer Institute.
This search is provided to aid in the planning stages of a
National Human Milk Monitoring Study. An objective of this study
will be to obtain national baseline estimates of certain chemicals
in milk.
17. Document Analysis a. Descriptors
b. Identlflers/Open-Ended Terms
c. COSATI Field/Group
18. Availability Statement
For release to public
IS. Security Class (This Report)
UNCLASSIFIED
21. No. of Pages
22. Price
(See ANSI-239.18)
999 IfMtfWCtlOfW Off
OraOMAL FORM 272 (4-77)
(Formerly NT1S-35)
Daoartment of Commerce
------- |