United States
Environmental Protection
Agency
Environmental Research
Laboratory
Narragansett Rl 02882
EPA 600 3 80 064
July 1980
Reeearefc and Development
Effects of Thermal
Pollution on Pelagic
Larvae  of Crustacea

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                                             EPA-600/3-80-061t
                                             July 1980
EFFECTS OF THERMAL POLLUTION ON PELAGIC LARVAE

                 OF CRUSTACEA
                 A.  N.  Sastry
        Graduate School of Oceanography
          University of Rhode Island
         Kingston, Rhode Island 02881
                Grant  R-800981
                Project  Officer

                 Don C.  Miller
       Environmental Research Laboratory
       Narragansett, Rhode Island 02882
      ENVIRONMENTAL RESEARCH LABORATORY
      OFFICE OF RESEARCH AND DEVELOPMENT
     U.S.  ENVIRONMENTAL  PROTECTION  AGENCY
      NARRAGANSETT, RHODE ISLAND 02882

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                                  DISCLAIMER
     This report has been reviewed by the Environmental Research Laboratory,
Narragansett, U.S. Environmental Protection Agency,  and approved for  publi-
cation.  Approval does not signify that the contents necessarily reflect the
views and policies of the U.S. Environmental Protection Agency,  nor does the
mention of trade names or commercial products constitute endorsement  or re-
commendation for use.
                                     ii

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                                   FOREWORD

     The Environmental Research Laboratory of the U.S. Environmental
Protection Agency is located on the shore of Narragansett Bay, Rhode Island.
In order to assure the protection of marine resources, the laboratory is
charged with providing a scientifically sound basis for Agency decisions on
the environmental safety of various uses of marine systems.  To a general
extent, this requires research on the tolerance of marine organisms and
their life stages as well as the tolerance of ecosystems to many forms of
pollution stress.

     This report describes a three-year study undertaken to determine the
environmental requirements for development of pelagic life stages of some
epibenthic crustaceans from the coastal and primarily estuarine environ-
ments.  The effects of temperature changes on the development, metabolism
and survival of the larval stages of the crustaceans are presented.
                                             Tudor T.  Davies
                                             Director
                                     iii

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                                 ABSTRACT

     Studies have been conducted to determine the effects of temperature
singly and in combination with other environmental factors on the develop-
mental and survival rates, metabolic adaptation and tolerance limits of
larvae of selected epibenthic crustaceans from the New England region.  Six
species, Cancer irroratus, Cancer borealis and Homarus americanus from the
coastal area'(high salinity), and Palaemonetes pugio,- Pagurus longicarpus
and Rhithropanopeus harrisii, from the primarily estuarine region (variable
salinity were used for this study. , Larvae of each species were cultured at
various combinations of .temperature and salinity to establish the combina-
tion contributing to highest survival rates and to determine the limits for
complete development of each species.  Temperature and salinity limits and
the optimal combination for development varied interspecifically.  Generally,
coastal species had a more restrictive temperature range for complete devel-
opment than estuarine species.

     The effects of daily cyclic temperatures vs. a comparable constant re-
gime on the development and survival rates of larvae were variable. Survival
of larvae of C_. irroratus cultured under certain daily cyclic regimes was
better.  In contrast, larvae of P_. pugio cultured under daily cyclic re-
gimes showed no significant differences in either survival or developmental
rate when compared to those at constant temperatures.

     Metabolic responses of C_. irroratus, II. americanus and P_. pugio larvae
cultured at temperature and salinity combinations optimal for their max-
imum survival rate were determined over a graded series of test temperatures.
Larval stages of the three species exhibited thermal sensitivity (CL >2),
insensitivity or compensation (l
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stresses -were combined, the thermal tolerance limits of C_. irroratus larval
stages were altered.

     Environmental thermal alterations can affect survival, developmental
rates and metabolism of developing larvae of crustaceans.  The specific ef-
fects of thermal alteration will vary during the course of larval develop-
ment in a manner characteristic to each species.  The nature of these effects
will be influenced by the organisms recent thermal history, as illustrated
by the higher survival rate of larvae reared under cyclic temperature con-
ditions than at a single constant temperature.   Further, these effects are
modified as other environmental parameters, such-as dissolved oxygen and
salinity interact with temperature.  Generally, estuarine species have a-
daptive capacities for development and growth over a wider range of environ-
mental conditions than coastal species.

     This report was submitted in fulfillment of  Grant number R 800981 under
the sponsorship of Environmental Protection Agency.   Work was completed as
of September 1976.

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                               CONTENTS

Foreword	iii
Abstract	 iv
Figures	viii
Tables	    x
Acknowledgements	xii

   1.  Introduction	1
   2.  Recommendations	^
   3.  Conclusions	3
   k.  Materials and Methods	...5
   5.  Experimental Results	10
   6.  Discussion	U3

References	k6
                                vii

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                                   FIGURES

 Number                                                               Page

 1  Larval stages of Cancer irroratus.   I-V,  zoeal  stages; M, megalops.,11

 2  Larval stages of Cancer borealis.   I-V,  zoeal stages; M, megalops... 12

 3  Temperature and salinity limits for complete larval  development
    of six species of crustaceans from  Narragansett Bay  and vicinity.... 14

 k  Percentage survival of larvae to post-larval stages  for five  species
    of crustaceans reared in different  combinations of salinity and
    temperature	14

 5  Survival of Cancer irroratus larvae to the post-larval stage  in
    different combinations of salinity  and temperature.  The larvae
    resulted from eggs hatched in 30 o/oo salinity  at  15 C in dif-
    ferent seasons	15

 6  Isopleths of mortality of larvae to the  post-larval  stage for
    primarily estuarine and coastal  crustaceans in relation to
    temperature and salinity conditions	l6

 7  Effect of temperature on the duration of larval development of
    primarily estuarine and coastal crustaceans	l8

 8  Effect of constant temperature on development time for larval
    stages of Cancer irroratus. „	20

 9  Effect of salinity on the duration  of larval development of
    primarily estuarine and coastal crustaceans	21

10  Percentage survival of Cancer irroratus  larvae  at  constant  and
    cyclic temperatures	24

11  Duration of larval development of C_. irroratus  at  constant  and
    cyclic temperatures	26

12  Survival of Cancer irroratus larvae to the post-larval  stage
    under constant and comparable cyclic temperature regimes  (A)
    The duration of larval development  under constant  and comparable
    cyclic temperature regimes (B)	2J
                                                                         •**--
13  Percentage survival of Palaemonetes pugio larvae at  constant
    and daily cyclic temperatures	29

                                    viii

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                              FIGURES (cont'd)

 Number                                                               Page

lU  Duration of larval development of Palaemonet es pugio at
    constant and daily cyclic temperatures ............................ 30

15  Metabolic-temperature response of different larval stages of
    Cane er irroratus .................................................. 31

16  Metabolic-temperature response of different larval stages
    of Cancer boreal is ................................................ 31

IT  Metabolic temperature responses (as Q-,_ values) of larval stages
    of Cancer boreal is and Palaemonet es pugio cultured at constant
    20 C and 30 o/oo salinity ......................................... 32

18  Metabolic-temperature responses (as Q]_Q values) of larval stages
    of Cancer irroratus cultured in 30 o/oo at constant 15 C and
    cyclic 10-20 C [[[ 33

19  Metabolic -temperature responses (as Q^Q values of larval stages
    of Homarus americanus cultured in 30 o/oo at constant 20 C
    and daily cyclic 15-25 and IT . 5-22. 5 C temperature
20  Metabolic-temperature responses (as Q]_Q values) of larval stages
    of Palaemonet es pugio cultured in 30 o/oo salinity at constant
    20 C and daily cyclic 15-25 C temperatures ........................ 35

21  The effects of daily cyclic and constant temperatures on the
    activities of lactate dehydrogenase, malate dehydrogenase
    and glucose 6-phosphate dehydrogenase in Cancer irroratus
    larval stages cultured at constant 20 C and 10-20 C daily
    cyclic temperatures ................................... ..... ....... 38

22  Cancer irxroratus .  Effect of larval stage on LD^g values for
    temperature.  Open circles: 120 min exposure;  filled circles:
    2UO minute exposure.   1-5Z: zoeal stages; M, megalops ............. 39

23  Cancer irroratus .   Effect of temperature on LD^g of oxygen
    for different larval stages ... .................................... ^0
2k  Cancer irroratus.  Effect of larval stage LD^o value for oxygen.. „
25  Acute temperature tolerance limits for three species of crustaceans
    cultured under constant conditions optimal for their survival.  (C_.

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                                   TABLES

 Number                                                              Page

 1  Distribution, ecology and breeding period of seven species
    of crustaceans used in the study	6

 2  Egg incubation and larval culture conditions for  six  species
    of Crustacea	7

 3  Variability in the number of larval stages during development
    of Palaemonetes pugio cultured at different combinations  of
    temperature and salinity	10

 U  Mean (+_ SD) days for complete development to post-larval  stage
    in various combinations of temperature and salinity for five
    species of crustaceana	J-9

 5  Equations describing the development time for  larval  stages
    of C_. irroratus at different constant temperatures	20

 6  Variation in the survival and duration for complete development
    of geographically separated populations of three species of
    crustaceans	22

 7  Duration for development to the third and fourth  larval  stage
    of H. am eric anus from different geographical regions	33

 8  Survival of C_. irroratus larval stages at constant and cyclic
    temperatures	2^

 9  Statistical analysis testing the significance  of  differences
    between survival of larvar stages of Cancer irroratus cultured
    at constant and cyclic temperatures	25

10  Mean days and the proportion of total development time (hatch
    to crabs) for each larval stage of C^. irroratus at constant
    and cyclic temperatures	25

11  Fatty acid methyl esters identified in developing larval  stages  of
    H. americanus cultured at constant 20 and 15-25 C cyclic  temperatures. 37

12  Activities of lactate dehydrogenase determined from crude cell-
    free homogenates of Cancer irroratus larvae cultured  under cyclic
    and  constant temperatures	3o

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                                TABLES (cont'd)

Number                                                                 Page

13  Cancer irroratus:   ^50 "values for temperature for 120 min and
    2^0 min exposure .times* "by stage	39
                                     XI

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                            ACKNOWLEDGEMENTS

     The financial support of the Environmental Protection Agency under
Grant Wo. R-800981 is gratefully acknowledged.  Dr. Don Miller, Project
Officer, has been particularly helpful in carrying out this project.

     The project was carried out at the Graduate School of Oceanography,
University of Rhode Island, Kingston, Rhode Island under the direction of
A. N. Sastry with the assistance of Dr. Sandra L. Vargo.  Technical
assistance was provided "by Ms,. Shirley Barton, Ms. Sharon Pavignano,
Ms. Joyce Blaisdell, Mr. John Laczak, Mr. Ross Ellington and Mr. John
McCarthy.  Ms. Sharon Pavignano provided invaluable assistance in the
preparation of the final report.
                                   xii

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                                  SECTION  1

                                 INTRODUCTION

     The possible effects of thermal alterations of the coastal and estuarine
environments from conventional and nuclear power plants has become a concern
to the public during the past several years.  The constraints of thermal in-
crease in these bodies of water are determined by consideration of the effects
on the biotic communities.  The adaptive capacities of organisms either to a
direct increase of water temperature, or the changes in the physico-chemical
properties of sea water due to increased temperature are important consider-
ations for determining water quality criteria.  An important issue then in
thermal pollution of the environment is to assess its short and long term
impact on biotic communities which may eventually result in alterations in
the structure and functioning of these ecological systems.   To develop the
capability for assessment and prediction of thermal alterations of the en-
vironment, there is a need for a comprehensive understanding of the effects
of thermal changes, singly or in combination with other factors, on all the
life stages of populations within the communities.

     An extensive body of literature evaluating the effects of thermal pol-
lution on organisms has been already published (Clark, 1969; Jensen, et al.,
1969; Krenkel and Parker, 1969; Nylor, 1969; Hargis and Warinner,  1970;
Gibbons and Shiritz, 197^-; Esch and McFarlane, 1976; Coutant and Talmage,
1977).  It is generally recognized that temperature changes in the environ-
ment affect metabolism, growth, reproduction and development,  and activity
and behavior of the organisms.  The functional activities of organisms are
performed within a temperature range characteristic to each species (Prosser,
1971; Vernberg and Vernberg, 1972).  Within the tolerance range, physiologi-
cal rate processes are altered relative to changes  in the ambient  water
temperature.  However, many organisms have capabilities to  regulate their
phsiological rate functions within a certain temperature range (Bullock,
1955; Hazel and Prosser, 197^-; Wieser, 1973).   These adaptations to changes
in the thermal environment play an important role in their  ecology and dis-
tribution.  At either extreme of the tolerance range, there is a point beyond
which the organisms are unable to survive.   The adaptations which favor
regulation of physiological rate processes within the tolerance range and  the
limits may vary with the stage of life cycle and also with  interactions of
other environmental factors (Sastry and Vargo, 1977).  The  synergistic inter-
action of multiple factors in the environment  makes it difficult to describe
and evaluate the complex relationship between organisms and their  environment-
al alterations under natural conditions.   One approach to determine the ef-
fects of temperature changes on organisms is to measure alterations in their
physiological rate processes within the tolerance range as  well as measuring
the thermal limits for survival.   Since a number of physical,  chemical and
biological factors interact with the organisms under natural conditions to

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affect their distribution, abundance and survival, laboratory studies  of
temperature effects must be extrapolated with caution to a field situation,
keeping in view the experimental limitations.  None the less, laboratory
studies provide an understanding of the effects of environmental alterations
on the adaptive capacities of organisms and give some insight into the pro-
bable consequences to organisms under natural conditions.

     Effects of thermal alterations in the environment on adaptations of
adult marine organisms have been extensively studied (Kinne, 1962, 1963,
1970; Vernberg and Vernberg, 1971; Prosser, 1971; Wieser, 1973).  However,
the adaptations for functional activities and tolerance limits of the plank-
tonic early life stages of benthic organisms relative to changes in the
thermal environment are not well known.  Pelagic larvae are a vulnerable life
cycle link and their survival through complete development is important for
successful recruitment to the adult populations (Thorson, 1950; Meleikovsky,
1970).  During pelagic existence, the larvae are exposed to varying combin-
ations of temperature, salinity, light, food and other factors.  Of these
factors, temperature, acting either singly or in combination with others,
often is of major importance, to the development and growth, survival  and
distribution (Costlow and Bookhout, 196U; Sastry and Vargo, 1977). In the
present project, studies have been conducted to determine the effects of
temperature, singly and in combination with other factors, on development
and survival, tolerance limits and metabolic adaptation of larvae of  sev-
eral epibenthic crustaceans from the coastal (high salinity) and predom-
inantly estuarine waters of the New England region.

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                                 SECTION 2

                                CONCLUSIONS

     Thermal alterations affect the development and growth, metabolism and
survival of crustacean larvae.  The limits as well as the optimal conditions
for larval development are modified "by the thermal history of eggs prior to
hatching, the stage of larval development and  geographic origin of the
population.  Different combinations of temperature and salinity interact to
affect larval development and survival.  A species may exhibit an optimal
combination for survival and as environmental conditions deviate from this
optimum, survival is reduced.  Limits, as well as optimal combinations for
development, vary interspecifically.  Generally, complete development for
coastal (high salinity) species, Cancer irroratus, Cancer borealis and
Homarus americanus was limited to a narrower range of temperature and sal-
inity than predominantly estuarine species, Palaemonetes pugio, Pagurus
longicarpus and Rhithropanopeus harrisii.

     Time for complete development and percent survival can also be influ-
enced by use of a daily cyclic temperature regime.  Larvae of C_. irroratus
cultured under suitable daily cyclic regimes showed increased survival com-
pared to those at comparable constant temperatures.  The effects of daily
cyclic temperatures can vary interspecifically. however.   For P_. pugio,
development and survival rates were not significantly different  under daily
cyclic and comparable constant temperatures.

     Within the thermal tolerance range of a species, the metabolic responses
to temperature may vary, but each species will have a characteristic overall
response.  Larval stages of each species exhibited capacities for metabolic
rate compensation (l
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                                SECTION 3

                             RECOMMENDATIONS

     Culture studies of larvae of several predominantly estuarine and
coastal (high salinity) epibenthic crustaceans show that complete develop-
ment occurs within a temperature and salinity range which is characteristic
of each species.  Limits, as well as the optimal combination for survival,
vary interspecifically.  Limits, as well as optimal conditions for maximum
survival also varied with the prior environmental history of eggs  (i.e.
for temperature and salinity), stage of larval development and geographic
origin of the populations.  Developmental and survival rates are also al-
tered under daily cyclic culture temperatures relative to those at constant
temperatures.  The effects of fluctuating temperatures on development and
survival were more evident for coastal species than estuarine species.

     Larvae of the crustaceans examined in this study showed abilities for
metabolic regulation over a temperature range characteristic to each species.
The metabolic rate of larvae showed sensitivity, insensitivity or compen-
sation and depression of metabolic rate over the gradient of temperatures
tested.  Generally, the larvae of estuarine species were metabolically active
over a broader temperature range than coastal species.  The metabolic-
temperature response patterns of larvae also varied with the stage of de-
velopment of each species.  These patterns were altered for larvae cultured
under daily cyclic temperatures relative to those at constant temperatures.
The alterations in metabolic responses of larvae cultured under daily cyclic
regimes were underlined by qualitative and quantitative changes in fatty
acid methyl esters and also in the specific activities of enzyme systems
examined.

     The thermal tolerance limits of larvae were found to be generally
higher for the estuarine species than coastal species.  The tolerances of
larvae are modified when temperature and dissolved oxygen stress were com-
bined.

      Biochemical and physiological responses of developing larvae to temp-
erature and other interacting factors Meed to be examined when evaluating
the effects of thermal alterations on the development and growth.  In ad-
dition, the effects of varying environmental temperatures and their inter-
action with other physioco-chemical factors  on metabolism, development and
growth of larvae can also provide some valuable information on their abil-
ities for adaptation to altered thermal environment.  Studies on larvae of
species occuring in different habitats and as well those breeding in dif-
ferent seasons would provide valuable information regarding the probable  con-
sequences of environmental thermal alterations on the recruitment of young
to the adult populations in a geographic region.

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                                 SECTION U

                            MATERIALS AND METHODS
CULTURE OF LARVAE
     Larvae of six species of crustaceans, Cancer irroratus, Cancer borealis,
and Homarus americamis from the coastal zone (high salinity), and Pagurus
longicarpus, Palaemonetes pugio and Rhithropanopeus harrisii from predomin-
antly estuarine waters in Narragansett Bay have been cultured in the labora-
tory.  Details of their habitat, temperature and salinity conditions are sum-
marized in Table 1.  The general methods for incubation and larval cuture are
the same as described in detail by Sastry  (1970) and Sastry and Vargo (1977).
Ovigerous adults were brought to the laboratory, eggs removed and incubated
until hatching in 30 o/oo salinity at a temperature suitable for each species
(Table 2).  In the cases of H. americanus and P_. pugio, eggs were not removed
and the ovigerous animals were held at the incubation temperatures until
hatching.

     Within 2k hours from hatching of eggs in the laboratory, the larvae were
transferred to different temperature and salinity combinations for rearing.
Larvae were reared individually in compartmented plastic boxes containing
filtered sea water or in the case of H. americanus in glass crystallizing
dishes containing sea water.  Within 2U hours after hatching of eggs, the
larvae were maintained in Sherer controlled environmental chambers and were
exposed to a lU:10 LD cycle.  The sea water was changed on alternate days
and the larvae were fed daily on a diet of freshly hatched Artemia salina
nauplii.  Molting and deaths were recorded daily to quantify the patterns of
survival to complete development for each species at the various conditions.
Temperature and salinity effects were determined using a factorial design
to produce graded series of responses to constant 10, 15, 20 and 25 C and
salinities 10, 15, 20, 25, 30 and 35 o/oo.  The factorial design allowed
estimation of the range of overall effects and the interaction between dif-
ferent experimental factors (Alderdice, 1972).

     The morphological descriptions of the larval stages of each species ex-
cept C_. irroratus and C_. borealis have been reported in the literature.
Drawings and descriptions of larval stages of C_. irroratus and C_.  borealis
were made from larvae of known stages cultured in the laboratory under optimal
temperature and salinity conditions and placed in Permount  on a slide.
Whole mounts were made of fresh material, and appendages also dissected from
each stage and similarly mounted.  Scale drawings were made of whole mounts
and larval appendages with the aid of camera  lucida (Sastry, 1977a, b).   The
descriptions of these larvae and those of other species available from liter-
ture were used for recognizing different stages in the development of a
species in conducting the experimental work on their physiological and bio-

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Table 1  Distribution,  ecology and  breeding period of seven  species  of  crustaceans  used  in  the  study
            Species
  Geonraphical Distribution
                                                                                      Harrngansett  Bay and Vicinity
                                                                                                                   Habitat
                                                          Temperature  C
      Habitat             Coll eel. Ion    Prr-piUnn Period      and Salinity (o/oo)
  (Williams,1965)            locality                   during breeding period
     Pagurua  longicarpua   Nova Scotia  to Northern
                          Florida and  from Sanibel
                          Island,  Florida to Texaa

     Palaeaonetes pugio    Hasaachuaetta to Texaa
     Rhithropanopeua
       hanriaii
     Cancer  irroratus
     Cancer borealia
Canada to Mexico, north-
east Brazil,  introduced
to Heat Coaat of U.S.
and in parts  of Europe

Labrador to South Carolina
Nova Scotia to Tortugaa,
Florida and Bermuda
Common on harbor  beaches,
and in ahallow littoral
on a variety of bottoms.

Efltuarine waters  espe-
cially in submerged
vegetation

Estuarine, found  in
places always providing
shelter
Low water mark to  600 o,
ahallow bay in north and
deep waters in south

Between tidea  in rocka
to 870 m; shallow  baya
in north and deep  waters
in south
     Homarus americanua    Nova Scotia to New Jeraey    Sub-littoral rocky bottom
                                                       Boat basin    Late April to
                                                                     mid-June
                                                       Bissell's     Mid-June to
                                                       Cove          early September
Narrow River  Kid-June to late
              Augus t
Narraganaett  April  to early
Bay          July
                                                                                 Narragansett  July
                                                                                 Bay
                                                       Narraganaett   July
                                                       Bay and
                                                       vicinity
    Panopeua herbstii     Massachusetts to Brazil;
                          Bermuda
                            Estuarine, bottom com-
                            posed of  soft mud and
                            oyster shells
                           Pawcatuck
                           River
             July
                                     7.5-17.0  C
                                     31  o/oo
                                     20-25 C
                                     10-30 o/oo
22-27 C
13-26 o/oo
                                                                                                                     6-19 C
                                                                                                                     31 o/oo
                                     18-23  C
                                     31  o/oo
                                                                18-23 C
                                                                31 o/oo
18-23 C
31 o/oo

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chemical responses to temperature  changes.

     For experimental work on the  physiology and biochemistry, larvae of  each
species were mass cultured in 12 cm diameter finger bowls under previously
determined optimal temperature  and salinity combination producing the max-
imum survival.  The larvae were transferred frequently to fresh sea water and
provided with a diet of freshly hatched Artemia salina nauplii as previously
described.

           TABLE 2  EGG INCUBATION AND LARVAL CULTURE CONDITIONS
                    USED FOR SIX SPECIES OF CRUSTACEA
     Species
Egg Incubation   Temperature (°C)
Larval Culture Conditions

 Salinity (o/oo)    Number of Combinations
Cancer irroratus
Cancer boreal is
Homarus americanua
Pagurus longicarpus
Rhithropanopeug
harrisii
1S°C,
15°C,
20 °C.
15°C,
20°C,

30
30
30
30
25

o/oo
o/oo
0/00
0/00
o/oo

10
10
10
10
20

.15.20
.15,20
.15,20
.15,20
,25,30

.25
,25
,25
,25


10,
10,
15,
15.
10,

15,20
15,20
20,25
20,25
15,20

.25
,:">
.30
,30
.25

,30,35
,35
.35
.35
.30,35

24
24
20
20
18

 Palaemonetea pugio
20°C, 30 o/oo
                                10,15,20,25,30
                             5,10,15,20,25,30,35,40
                                                                    40
Effects of Daily Cyclic Temperatures on Larval Development

     Effects of daily cyclic  and comparable constant temperatures on develop-
mental and survival rates of  C^.  irroratus larvae hatched in 3P o/oo at 15 C
and P_. pugio larvae hatched in  30 o/oo salinity at 20 C were determined.
The larvae were reared in 10-20,  15-25, 12.5-17-5 and 17.5-22.5 C daily cyclic
temperatures and comparable constant 15 and 20 C under a lU:10 LD photoperiod.
The same culturing methods were used as for the temperature and salinity
studies cited above.  Molting and deaths were recorded daily to determine the
patterns of survival and duration of development.

Metabolic Responses of Larvae to  Temperature

     The temperature effects  on metabolism were determined by measuring the
oxygen consumption rates for  the  larval stages of C_. irroratus, H. americanus
and P_. pugio over a graded series of temperatures.  For the metabolic rate
determinations, larvae from mass  cutures of C_. irroratus in 30 o/oo salinity
at 15 C and H_. americanus and P_.  pugio in 30 o/oo salinity at 20 C were used.
The oxygen consumption rates  of C_.  irroratus and P_.  pugio were measured with
all glass differential microrespirometers (Sastry and McCarthy, 1973).  Met-
abolic rates were measured using  10-12 individuals of the first, second and
third stage zoeae, U-5 individuals of ^th and 5th stage zoeae and one of
megalops for C_. irroratus.  For P_.  pugio, one to four individuals of each
larval stage, depending upon  the  stage of development, were introduced into
each flask for respiration measurements.  The metabolic rates of II. americanus

                                       7

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larvae were measured for,U-5 individuals of first, second and third stages,
and one or two individuals of the fourth stage larvae introduced into each
flask.  A number of replicate runs (3-12) were made for larval stages of each
species over a graded series of temperatures between 5 and 30 C.  Larvae were
then weighed to the nearest microgram on a Cahn electrebalance.  The mean
oxygen consumption rate and the standard deviation were computed.  The regres-
sion    analysis of oxygen consumption as a function of weight of each life
cycle stage was performed and tested for significance by F test.  The mean
weight-specific oxygen consumption rates, or those values determined from
the regressions when those were significant, were plotted against temperature
to represent the metabolic temperature response patterns.  These values were
used to compute the QQ_Q for 5 C test temperature intervals to reveal changes
in metabolic response to temperature.

Fatty Acid Methyl Esters

     A known weight of each larval stage of C_. irroratus and II. americanus
were placed in 25 ml centrifuge tubes with teflon lined screw caps.  Ten ml
of 0.5 N KOH in methanol, and 5-0 ml of benzene were added to each tube, the
tubes were flushed with nitrogen, sealed and heated at 100 C for 30 minutes
with shaking for 10 min.  The saponified samples were cooled, 5-0 ml of 0,3
NHCL ware added, and the tubes were shaken and centrifuged.  The benzene lay-
er was drawn off and transferred to 50 ml pearshaped flasks and the aqueous
methanol phases were twice re-extracted with 5 ml portions of petroleum ether.
The petroleum-benzene extracts were evaporated to dryness under reduced pres-
sure.

     The extract residues were transferred to screw cap centrifuge tubes with
teflon lined caps, using 1 ml methanol and 1 ml of benzene.  One ml of BF^
methanol was added to each tube, the tubes were flushed with nitrogen, sealed
and heated in boiling water for 5 minutes.  Methyl esters were isolated by
adding k ml of H^O and k ml of petroleum ether.  Solvent was evaporated under
reduced pressure.

     Fatty acid methyl esters were separated by thin layer chromatography
using Me-palmitate (l6:0) and Me-decosahexaenate (22:6) as spotting standards.
The silica-gel plates were developed for 30 minutes in 95:5:1 petroleum ether,
ethyl ether and NaOII.  After drying the plates, they were sprayed with
bromophenol blue solution and the bands corresponding to the saturated and
unsaturated fatty acids were scraped.  The scrapings were added to a micro-
filter apparatus attached to an aspirator and eluted with 30 ml of CHClo.
The elutaht was evaporated to dryness in a 50 ml pearshaped flask.  The sam-
ple material was resuspended in a small amount of CHC^.

     Fatty acid methyl esters of the sample of each larval stage were an-
alyzed by Hewlet-Packard Model No. 5 1 A Gas Uhromatograph, equipped with
flame ionization detectors.  Fatty acid methyl esters.were quantitatively
identified by comparison of their relative retention time with those of
standard methyl esters.  The fatty acids in samples were determined by in-
corporating a fatty acid internal standard into the extraction with the
sample prior to saponification.  The peak area (height X width at half height)
of the internal standard methyl esters was then compared with the peak areas ^

                                      8

-------
of the sample methyl esters on the gas chromatogram.   The fatty acid methyl
esters were expressed as weight percent.   All solvents used were distilled
and blank solvents showed negligible quantities of fatty acids.

Enzyme Assays

     Specific activities of lactate dehydrogenase, malate dehydrogenase and
glucose 6-phosphate dehydrogenase were assayed for pooled groups of larval
stages of C_. irroratus cultured at 10-20  C daily cycle and 15 C constant
temperature.  Larvae were homogenized in  1:5 (weight/volume) of 5 mM Tris-
HC1 (pH T.5) and the resulting homogenate was centrifuged at 25,000  g in a
refrigerated centrifuge for 20 minutes.   The resulting supernatant was used
as the source of enzymes.  The assays were performed  using the following re-
action mixtures:  LDH, 0.01 mM NADH, 5 mM sodium pyruvate and 50 mM Tris-HCl
(pH T.5) in a total volume of 3.0 ml;
MDH, 0.01 mM HADH, 0.2 mM oxaloacetate and 50 mM Tris-HCl (pH 7-5) in a total
volume of 3.0 ml;
G6PDH, 0.15 mM NADP, 1.66 mM glucose 6 phosphate, 5 mM MgUl2 and 50 mM Tris-
HCl (pH 7.5) in a total volume of 3-0 ml.  Enzyme assay mixtures were equiil-
ibrated to 15 C prior to assay in a Zeiss PMQ II Spectrophotometer.   Enzyme
activities were expressed as y moles per  mg Lowry protein.

Acute Temperature and Dissolved Oxygen Tolerances

     Acute temperature and low dissolved  oxygen tolerances  for the larvae
of C_. irroratus, H. americanus and P. pugio were determined for each stage
of the three species.  The larval stages  were placed  in flat walled 25 ml T-
"type glass flasks designed for tissue culture, which  allow direct micro-
scopic examination of the larvae for testing.  Lethal temperature limits were
determined  under saturated dissolved oxygen conditions by bubbling with com-
pressed air.  The tests were conducted at 2 C intervals between 27 and 33 C,
using 10 larvae at each temperature.  After the flasks had been equilibrated
to the test temperature, the larvae were  introduced and the number surviving
was determined at 30, 60, 120 and 240 minute intervals.   Cessation of heart
beat was the criterion of death.  After testing, the  larvae from each flask
were returned to their culture temperature and the number of survivors was
determined after 24 hours.  The tolerance of larval stages  to  low dissolved
oxygen was determined by reducing the dissolved oxygen from saturation (4.2
to 6.2ml 02/3) to 0.2 ml 02/1  at  5 test  temperatures (10,  15, 20, 25 and 30
C) were used.  After the test, two 60 ml  oxygen samples were drawn from each
flask and analyzed by modified winkler method (Carritt and Carpenter, 1966).
The time intervals and criterion of death were the same.   The  LD^Q values for
temperature and dissolved oxygen were determined by the graphical method
(Goldstein, 1964).  Because the tolerance to low dissolved  oxygen has been
measured, the1 greater the LD^Q value ^he  lower the tolerance;  therefore,  the
LD^Q value is plotted as 1/LD^Q.  With this transformation,  the higher values
in the plot represent greater tolerances  (Vargo and Sastry,  1977).   In the
temperature and low dissolved oxygen tests, tolerances of individual larval
stages were highly variable for the 30 and 60 min.  time sampling intervals;
hence only the data for the 120 and 240 min.  time intervals  are given.   This
variability is probably due to differing  activity levels  resulting from
handling when the larvae were,  transferred to the test flasks.

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                                 SECTION 5

                            EXPERIMENTAL RESULTS
LARVAL DEVELOPMENT

     The methods for culture and descriptions of larval stages during complete
development of C_. irroratus and C_. borealis were not previously available.
Therefore, the larvae of both these species have been cultured and morpho-
logical features of the larval stages have been described (Sastry, 1970;  1977
a, b).  Larval development of both species includes five zoeal stages and a
megalops stage before metamorphosis to the crab stage (Figs.  1 and 2).
Larval stages of H_. americanus have been previously described   (Herrick,
1896; Hadley, 1909).  The development of this species includes four plankton-
ic larval stages.  Connolly (1925) described the four zoeal stages and a  meg-
alops stage in the development of R. harrisii.  Larvae of P_.  pugio were de-
scribed by Broad (1957).  In the present study, the number of larval stages
in the development of this species varied from 6 to 14 in various combinations
of temperature and salinity (Table 3).  Larval stages of P_. longicarpus cul-
tured in the laboratory have been described by Roberts (1970).  The larvae
pass through four zoeal stages and a megalops stage before metamorphosis to
the post-larval stage.

    TABLE 3.  VARIABILITY  IN THE  NUMBER OF LARVAL STAGES DURING DEVELOPMENT
             OF PALAEMONETES  PUGIO CULTURED AT DIFFERENT  COMBINATIONS OF
             TEMPERATURE  AND  SALINITY
     Temperature                       Salinity 0/00
c
15

20

25

10
8-lU
(10)
6-9
(8)
7-11
(3)
15
7-12
(10)
6-9
(8)
6-11
(9)
20
8-12
do)
6-9
(8)
6-11
(8)
25
8-12
(10)
6-10
(8)
6-10
(8)
30
9-12
do)
7-11
(8)
6-9
(7)
35
Q-ik
(10)
6-11
(8)
7-12
(10)
    Numbers in parenthesis indicate the model frequency

                                      10

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H
t-1
              1.3mm
                                       2.2 mm
                                                                        M
                                                                2.0 mm
                       IV
             Figure 1.   Life cycle stages  of C_.  irroratus I to V,  zoeal stages; M. megalops.

-------
H
ro
                Figure 2.  Larval stages of Cancer boreal is I to V, zoeal stages; M. megalops.

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EFFECTS OF TEMPERATURE AND SALINITY ON DEVELOPMENT AND SURVIVAL

Optima and limits

     The temperature and salinity requirements for complete development of
each species to the first crab or juvenile stage were determined by culturing
larvae in different combinations of temperature and salinity (Table 2).
Larvae of C_. boreal is completed the development only at 20 C in 30 o/oo (Fig.
3).  Survival at these conditions vas low (b.97«).  In contrast, the larvae
of C_. irroratus completed development in salinities from 25-35 o/oo at 10
and 20 C, and 20-35 o/oo salinity at 15 C (Fig. 3 and U).  The highest sur-
vival to the first crab stage was observed in 30 o/oo salinity at 15 C.
Ovigerous C_. irroratus are found in Narragansett Bay from November to early
July (Hilman, 19bU; Jones, 1973; Sastry and McCarthy, 1973).  Eggs of this
species removed from ovigerous animals collected between November and July
can be hatched when incubated in 30 o/oo salinity at 15 C.  Temperature and
salinity limits for complete development as well as survival under compar-
able conditions, varied for larvae hatched at different seasons (Fig. 5).
Larvae resulting from winter hatches completed development in 30 o/oo at IOC
and in 25-35 o/oo at 15 and 20 C.  Larvae from spring hatches completed devel-
opment in salinities from 25-30 o/oo and 10 C and 20 C, and between 20-35
o/oo at 15 C.  The larvae of summer hatches failed to complete development in
any salinity at 10 C, although at 20 C larvae completed development in 20-35
o/oo at 15 C and 25-35 o/oo salinity.  The previous thermal history and stage
of embryonic development prior to incubation affected the survival rate and
limits for complete larval development.

     Combined data analyzed for all seasons and represented as response
surfaces (Alderdice, 1972) showed that maximum survival of C_. irroratus larv-
ae to the crab stage occur between 28-35 o/oo at temperatures between 13-17
C (Fig. 6).  One hundred percent mortality of the larvae was predicted to
occur below 18 and above UO o/oo salinity t with 100$ mortality beyond these
limits  (Fig. 6).
     Larvae of II. am eric anus completed development to the post-larval stage
in salinities between 20-35 o/oo at 15 C and 15-30 o/oo at 20 C (Fig. 3).
Survival of larvae to the post-larval stage was higher in 35 o/oo at 15 C.
Combined data for larvae resulting from different hatches showed that II.
americanus larvae survive at a maximum rate of 80$ between 20-28 o/oo sal-
inity and 15-lb1 C.  Development of larvae to the post-larval stage was lim-
ited by 9 and 2k C and 5 and hO% salinity with 100$ mortality (Fig. 6).

     Larvae of P_. longicarpus completed development over a wider temperature
and salinity range than larvae of any other species.   The post-larval stage
was reached in salinities between 15-35 o/oo at 10 and 15 C, 20-30 o/oo at
20 C and 25-30 o/oo at 25 C (Fig. 3).  Survival of larvae of this species
was uniformly high in all salinities from 15-35 o/oo at 20 and 25 C (Fig.  U).
No single optimal combination of temperature and salinity for survival could
be identified for this widely tolerant species (Fig.  6).  Complete develop-
ment of R_. harri-sii larvae was observed in 20-35 o/oo at 25 C and 15-30 o/oo
at 30 C (Fig. 3).  Survival of larvae to the first crab stage was highest in
25 o/oo at 25 C.  Larvae of R_. harrisii tolerated the highest temperatures to
complete development of any of the species studied (Fig. k).

                                     13

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              40r-
              30
                   C. irroratus \//\
                   H. amer/canus (TT7T)
                   C. borealis    •     P. longlcarpas
            - 20
            <  10
I
                            I
I
                      I
             P. pug/o
             R. harrisii  \_ _ j
                      10    20    0    10    20    0
                             TEMPERATURE,  C
                10
                                      20   30
Fig. 3. Temperature and salinity limits  for complete larval development of
six species  of crustaceans from Narragansett Bay and vicinity.
Fig. h.  Percentage survival of larvae to the post-larval stages  for five
species of  crustaceans reared in different combinations of  salinity and
temperature.

-------
Fig. 5-  Survival of C_. irroratus larvae to the post-larval stage in different
combinations of salinity and temperature.  The larvae resulted from eggs
hatched in 30 o/oo salinity at 15 C in different seasons.
                                     15

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     >-
     I-
        12
        16
       20
=  24
_J
<

   28



   3;



   36



   4C
                                           100%
                                             100%
                                                 \20%       80°/,

                                                  . —H. amerfcanus
                                                  \—C.irroratus
                                                  »— — P nun if.


                                                  \
                                                         P. pugio
                        12     16     20    24     28

                               TEMPERATURE C
                                                    32
36
                                                                      \
40
Fig. b.  Isopleths of mortality of larvae to the post-larval stage for
primarily estuarine and coastal crustaceans in relation to temperature-

salinity conditions.
                                      16

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Duration of larval development

     Temperature significantly affected the duration of larval development
of C_. irroratus, H. americanus and P_. pugip  (Fig 1).  In all these species,
the duration for complete larval development decreased with the increase of
temperature.  In comparison, the developmental rate of P_. longicarpus was
less a-ffected by temperature.  The larvae of R_. harrisii  showed still anoth-
er pattern of temperature effect on the rate of development, developing at a
slower rat.e at 30 C compared to those at 25 C.  The duration of larval de-
velopment o.f all the species is affected "by the temperature, "but the rates
vary interspecifically (Fig. 7 and Table k).

     The effect of temperature on the rate of development of each larval
stage of C_. irroratus was determined to examine whether successive larval
stages in the development of a species are differentially affected by the
temperature.  The first zoeal stage of C_. irroratus developed at a slower
rate than the succeeding zoeal stages (Fig. b and Table 5).  The rate of de-
velopment of the zoeal stages decreased significantly at temperatures below
10 C; developmental rate remained about the same at temperatures above 25 C.
The duration of megalops stage is much longer than any of the preceeding
zoeal stages.  The duration of the megalops stage also became significantly
increased below 15 C and decreased slightly above 20 C (Fig. 8).

     In contrast, salinity had much less effect on the rate of development
than temperature (Fig. 9  and Table 4).  The duration of development of each
species was different at comparable salinities.  Contrasting salinity con-
ditions within the range of tolerances did not significantly affect the rate
of development of P_. longicarpus and P. pugio.  Larvae of R_. harrisii de-
veloped at about the same rate in salinities between 30 and 35 o/oo and at
slightly slower rate in 25, 30 or 35 o/oo salinity.  In contrast,  the larvae
of II. americanus developed at a slower rate in salinities above and below
25 o/oo.

Variation^ in geographically separated populations

     All the species selected for this study are distributed over  a wide
geographical range (Table 1).  Information on the duration of complete de-
velopment and survival of larvae to the post-larval stage of geographically
separated populations are not available for most species.   Data are avail-
able for R_. harrisii and P_. pugio populations from North Carolina  (Costlow,
et al_., 1966; Broad, 1957) and are compared with Rhode Island populations
cultured under somewhat similar conditions (Table 6).  Rhode Island larvae
of R_. harrisii took longer to complete development and their survival was
much lower compared to those from North Carolina.  In comparison,  survival
of_P. pugio larvae from Rhode Island was higher (91.8$) compared to those
from North Carolina (65%).  Larval development of the Rhode Island population
was completed between 10-31 days compared to 17-21 days required for the
North Carolina population (.Table b).  There is an indication that  the dura-
tion of H. americanus larval development also varies for geographically
separated populations  (Table 7).
                                     17

-------
            30-
            70-
            60-
            50
         cn
            30
            20
             10
o H.americanus
• C. irrorafus
A P. pugio
m R. fiarrisii
A P. long/carpus
                               10       15       20
                              TEMPERATURE  C
                                      25
30
Fig. 7-  Effect of temperature on the duration of larval development of
primarily estuarine  and  coastal crustaceans.
                                      18

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TABLE k.  MEAN  (+_ SD)  DAYS FOR COMPLETE DEVELOPMENT TO POST-
          LARVAL  STAGE IN VARIOUS COMBINATIONS OF TEMPERATURE
          AND SALINITY FOR FIVE SPECIES OF  CRUSTACEANS

Species

Palaenonetes
pugio
Paugurs
longi carpus

Rhithropanopeus
harrisii

li
H. americanus

C. irroratus

Temp C

15
20
25
10
15
20
25
30
15
20
15
Salinity
10 15
101 + 96.5+
3.0 11.68
34.1+ 34.6+
3.2~ 3.3
26.32+ 30.07+
2.7 3.66
46.5 44.0
39.0+ 31.6+
3.46 3.81
31 .6+
5.06
— —
55
-
20
84.46+
6.87
31.66+
2.28
22.64+
2.52
35.5
32.0+
4.12
29.8+
4.02
36
24
79.67+
7.02
53.7+
8.27
48.33+
3.51
25
86.3+
6.3T
32.09+
2.21
23.91+
3.07
41.0
7
26.3+
2.81
24
26
97.0+
4.24
42.27+
7.89
56.39+
5.13
30
81.37+
18.34
32.06+
2.21
23.56+
3.04
38.5
7
25.3+
2.73
22
27
7
46.36+
7.28
55.73+
4.24
35 40
94.72+
15.03
33.27+
2.87
26.19+
4.70

22
76.0+
2.77
60.26+
7.42
            20            ...     40.02+  36.03+  38.19+
                                            9.94    3.83   6.69
                               19

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                TABLE 5-  EQUATIONS  DESCRIBING THE DEVELOPMENT TIME
                FOR LARVAL STAGES  OF CANCER IRRORATUS AT DIFFERENT
                CONSTANT TEMPERATURES (FROM SASTRY,  1976).

Larval stage*
I
II
III
IV
V
Megalops
Equation
D'SOO/CT+l-SS)1-44
D = 498/(T+1.72)l-JS
D = 500/(T+1.63)'-SS
D = 500/(T+6.6)'-40
D = 999/(T+2.06)'-70
D = 500/(T-3.19)1'"
                      *Stages I to V are zoeal stages.
                       -20
                      UJ
                      2
                      UJ

                      Q.

                      3 10
                              MEGALOPS
                                     15
                                TEMPERATURE, C
25
Figure 8.  Effect  of temperature on development time for larval stages
of C. irroratus.   Dashed lines on the curves represent  extrapolated valu
                                      20

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        03
                 o H. amencanus
                 • C. irroratus
                 A P. pugio
                 • /?. harrisii
                 A P. longicarpus
10-
            0
                               15       20      25

                               SALINITY  %o
                                            30
35
Figure 9-  Effect  of salinity on the duration  of larval development  of
primarily estuarine and coastal crustaceans.
                                       21

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TABLE  6.   VARIATION  IN THE SURVIVAL AND DURATION FOR COMPLETE DEVELOPMENT
OF GEOGRAPHICALLY SEPARATED POPULATIONS OF THREE SPECIES OF CRUSTACEANS.


Species


Panopeua herbatii






Rhithropanopeug
harrisii



Palaemonetea pugio
Rhode Island
Duration
T (C), S (o/oo) Z Survival Days
20 C 52 30-38
32 o/oo

25 C 48 20-32
32 o/oo
25 C 20.7 20-30
25 o/oo
25 C 2.0 22
35 o/oo

30 C 1.89 23-24
15 o/oo
30 C 4.08 23-30
25 o/oo
25 C 91.8 18-31
30 o/oo
North Carolina*

T (C). S (o/oo)
20 C
31.1 o/oo

25 C
31.1 o/oo
25 C
25 o/oo
25 C
35 o/oo

30 C
15 o/oo
30 C
25 o/oo
25-27 C
Duration
Z Survival Day*
0


3 33-35

83 15-23

23 16-21


14 15-22

60 11-15

65 17-21
 * Data from Costlow, Bookhout and Monroe     (1966); Broad (1957)
                                       22

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TABLE 7.   DURATION (DAYS) FOR DEVELOPMENT TO  THIRD AND FOURTH LARVAL STAGE
OF H_. AMERICANUS FROM DIFFERENT GEOGRAPHICAL  REGIONS (THE FOOD  FOR LARVAE
AND CULTURE CONDITIONS ARE  SOMEWHAT DIFFERENT).
Geographical
region

St. Andrew's
Canada



Nova Scotia &
Maine
Culture
temperature
C
6-7
10
14
19
24
15
19-20
Days to
4th stage

120
54.5
26.5
13.5
10.5
25
15
Days to Reference
5th stage


100
50 Tempi em an (1936)
28

Sherman and Lewis
1967; Scaratt, 1968
         Martha's      19-20
         vineyard, Mass.
13.6
Hughes and Mattheissen,
1962
Rhode Island


10
15
20
71
29
23
109
76
46

This study

                                       23

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Effects of  constant and daily cyclic  temperatures

     The  effects of daily cyclic  and  comparable constant temperatures on the
duration  of larval development and  survival were determined  for the larvae
of C_.  irroratus and P_. pugio.

     Larvae  of £.  irroratus cultured  at 10  to 20 and 25 C
daily cyclic  temperatures experienced greater survival
than those  at comparable constant temperatures  (Fig. 10 and  Tables 8 and 9).
Survival  of larvae was less at 12.5-17.5  C  cycle than that at the 10-20 C
cycle.  Larvae cultured at the 17.5-22.5  C  cycle developed only to the meg-
alops  stage.  Duration of the zoeal stages  at both 12.5-17-5 C  and 10-20 C
daily  cycles decreased and megalops duration increased compared to that at
constant  15 C (Fig. 11 and Table  10).  The  duration of the megalops stage in-
1UU



% SURVIVAL
Ul
3 0

— tjxl Constant —
CZ2 10°C cycle
G3 5°C cycle
-
Xv

m

73



i

I
;
-
-
-


$•::





A-:-
I
V





y/.

—

|j
                                                                     !
       10  15  20 10-  15- 12.5- 17.5-
                  20  25  17.5 22.5
             TEMPERATURE. °C
                 (a)
15  20 10-  15-  12.5-
       20  25  17.5
  TEMPERATURE. °C
      (b)
15  20 10-  15-  12.5-
       20  25  17.5
 TEMPERATURE. °C
      (c)
 Figure 10.  Percentage  survival of £. irroratus larvae  at  constant and' cyclic
 temperatures, (a) Hatch to megalops, (b) Megalops to crab, (c) Hatch to crab.
 TABLE 8.  SURVIVAL OF  C_.  IRRORATUS LARVAL STAGES AT  CONSTANT AND CYCLIC
 TEMPERATURES,
                        Survival at
                    constant temperature, %
           Survival at
        cyclic temperatures, %
              Larval
              stage*   10°C 15°C 20°C  2S°C 10-20°C 15-25°C 1Z5-17.S°C  17.5-2ZS°C
I
II
III
rv
V
Megalops
54
37
32
20
15
0
85
78
72
66
60
40
76
68
58
47
31
17
39
17
6
0
0
0
88
86
84
79
78
63
87
83
78
75
71
39^
82
72
66
58
.^, 49
12
76
60
40
27
20
0
               •Stages I to V are zoeal stages.

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    TABLE 9.  STATISTICAL ANALYSIS TESTING THE SIGNIFICANCE OF DIFFERENCES BETWEEN SURVIVAL OF LARVAL
    STAGES OF C.  IRRORATUS CULTURED AT CONSTANT AND CYCLIC TEMPERATURES.


Temperature, °C
15 vs. 10-20
20 vs. 15-25
15 vs. 12J-17.5
20 vs. 17.5-22.5
10-20 vs. 15-25
12.5-17.5 vs.
17.5-22.5
10-20 vs. 12.5-
17.5
15-25 vs. 17.5-
22.5
Larval stages t
I II ID IV V Megalops
_ _ _ - + +
— + + + + +
_ _ _ — — +
_ _ + + - +
_ _ _ - - +

_ _ _ + + +

_ — + + + +

_ + + + + +
ro
  'Minus (—) means not significant; plus (+} means p < 0.05
(Pearson and Hartley, 1954).
  t Stages I to V arc zocal stages.
    TABLE 10.   MEAN DAYS AND PROPORTION OF TOTAL DEVELOPMENT TIME (HATCH TO  CRABS) FOR  EACH LARVAL STAGE OF
    C. IRRORATUS AT CONSTANT AND CYCLIC TEMPERATURES.

Constant temperatures
Larval
stagef
I
11
III
IV
V
Megalops
10°C
Days
15.4 ± 6.8
26.0 1 6.6
38.7 ± 10.3
41.4 ± 12.6
6 1.3 ±4.4

15°C
Days
6.5 ± 1.4
12.9 ± 2.3
19.4 ± 2.7
26.0 i 2.8
35.0 ± 3.2
55.7 ± 4.2

%
11.6
11.4
11.6
11.8
16.1
37.5
20° C
Days
5.2 ± 1.3
9.1 ± 2.0
13.2 ± 2.5
17.8 i 1.7
24.2 ± 2.0
36.0 ± 3.8

%
14.4
10.8
11.3
12.7
!.7.7
32.8
25°C
Days
4.2 ± 2.4
8.8 i 0.41
13.0



10-20°
Days
5.1± 1.0
11.4± 3.5
17.9 ± 3.5
23.5 * 3,.5
30.} 4 3-5
56.0 ± 5.5
C
%
'9.1
11.3
11.6
10.0
11.8
46.3
Cyclic
15-25°C
Days
3.6 ± 1.2
7.9 ± 2.0
13.6± 2.8
19.1 ± 3.5
24.3 ± 3.9
57.9 ± 11.3
temperatures

%
6.2
7.4
9.8
9.5
8.9
58.0
12.5-17.
Days
5.6 ± 2.7
11.6 ± 3.6
18.4 ± 3.4
23.9 ± 3.0
28.9 ± 2.4
51.5 ± 2.4
5°C
%
10.8
11.7
13.2
10.7
9.7
43.9
17.5-22.5°C
Days
6.9 ±4.7
13.3 ± 5.1
18.5 * 6.4
24.8 ± 3.3
30.4 ± 3.7

                •Weighted mean.
                tStages I to V are 7 oca I stages.

-------
creased considerably at' the 15-25  C  cycle  compared to  constant  20  C.   The
megalops was the most thermally  sensitive  stage in the larval development of
C_. irroratus.

     Larval survival from  eggs of  £.  irroratus  hatched under daily cyclic
temperatures and reared under the  same temperature cycle showed an increase
in the survival to the crab stage, compared to  larvae  hatched at constant
temperature and reared under daily cyclic  regime (Fig. 12.)   Survival in-
creased by 9%  for the 10-20 C cycle, 1% for the 15-25  C cycle and 1.5% for
the 12.5-1T.5  C cycle.  Larval development time whether eggs hatched under
cyclic or constant temperature,  was  not significantly  different for the 10-20
and 12.5-1T.5  cycles.  However,  for  the 15-25 C cycle, the development time
of larvae hatched under cyclic temperatures was less than that  for larvae
hatched under  constant conditions  (Fig. 12).
DU
40
20
« n

P
H20
01
0.
O
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rrr



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Cor
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5UC

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ttant ~
C cycle
cycle
—
|-
                            10   15  20  10- 15-  12.5- 17.5-
                                       20   25  17.5 22.5
                                  TEMPERATURE.°C
 Figure-11.  Duration  of larval  development  of C_.  irroratus  at  constant  and
 cyclic temperatures,   (a)  Hatch to  crab,   (b) Megalops.   (c) Hatch to meg-
 alops.
                                       26

-------
I
a
ID
ro
                    80
                     60
                    40
                     20
A
E
- c
3
D
Eggs 8 Larvae
Cycled
Larvae Cycled

I
—
I

1
                            15   20
                          CONSTANT
                                                80
                                                60
40
                                                20
                                                                     B
                           10-2015-25125-175
                              CYCLIC

                                TEMPERATURE  C
                                                                                1
                                                                   A Eggs 8 Larvae
                                                                     Cycled
                                                                                |   O Larvae Cycled
       15  20
     CONSTANT
10-20 15-25 12.5-175
    CYCLIC
      Figure 12.   Survival  of  C_.  irroratus larvae to the post-larval stage under constant and comparable
      cyclic temperature  regimes  (A).   The duration of larval development under constant and comparable
      cyclic temperature  regimes  (B).

-------
     Larvae of P. pugio cultiired at 12.5 to 17-5 and 10-20 C daily cyclic
temperatures survived to the post-larval stage slightly better than those at
comparable constant 15 C (Fig. 13).  No significant differences in the rate
of survival to the post-larval stage were observed at IT.5-22.5 and 15-25 C
daily cycles and at comparable constant 20 C.  Duration of development to the
post-larval stage was slightly longer at constant 15 C compared to that at
10-20 or 12.5-1T.5 C daily cycles.  No significant differences were observed
in the duration of development at constant 20 C and 15-25 or 17.5-22.5 C
daily cyclic temperatures (Fig. ll|).

     Mean weight of the developmental stages of C_. irroratus increased pro-
gressively from first zoeal stage to the crab stage.  There were no sig-
nificant differences in the weight  of larval stages cultured at 10-20 C
daily cycle and comparable constant temperature (p<0.01).  Mean weight of the
larval stages of P_. pugio also increased progressively with development.


METABOLIC-TEMPERATURE RESPONSES

Larvae Cultured at Constant Temperatures

     Larvae cultured at a temperature and salinity producing highest survival
to the post-larval stage  (C_.  irroratus,15C-30 o/oo; C_. borealis, 20 C-30 o/oo;
P_. pugio, 20  C-30 o/oo) showed both inter and intraspecific variation in
their metabolic responses to  temperature.  The first stage larvae of C_.
irroratus were metabolically  active over a temperature range of 5-25 C  (Fig.
15), with a Q-|_Q close to 2.   For  successive  stages, the temperature range
for depression  (Q-,Q<1) of metabolic rate was about the same, but differences
in temperature ranges for sensitivity  (Qj_Q>2) and compensation 0-
-------
ro
MD
                                             25      30
20-10   25-15   22.5-17.5  17.5-12.5
                                   CONSTANT
                                                      C U LTURE
          CYCLING
                                                 TE  MPERATURE
    Figure 13.   Percentage survival of Palaemonetes pugio  at  constant and daily cyclic temperatures,

-------
                   100




                   80




                   60

                CO
                >-
                <
                Q 40

LO
O

                   20
                                    20      25      30             20-10    25-15   225-175   17.5-12.5
                                                     C U LT U R E
                                                 TE MPERATURE
CONSTANT         C U LT U R E           CYCLING
       Figure lU.   Duration of larval development of Palaemonetes pugio at  constant  and daily cyclic temp-
       eratures .

-------
*o-
4.O-
              i.o:
              O.T'
                   ZI
                                                         ZW
              ZJJ-

              1.0
              or
              oa
                    ZZZ
                                       ZZ
                                                          MCCALOPS
                0   9   a  IS  2O  29 0   3   10  IS  W  M 0   9   10  19  20   23
                                                 TEMPERATURE *C
Figvire 15.  Metabolic-temperature response of different larval stages  of
Cancer irroratus;  ZI to ZV  zoeal stages.
               to
               *
             O 03-
             * *°1
               to-
               or'.
               as.
                     ZJZ
                                                           MEQAlOn
                 O  S   IO02029O  S  10   19  »  23 0  9   M  19  2O  29
                                                  TEMPERATURE %
Figure l6.  Metabolic-temperature  response of different  larval stages of
Cancer boreal is-; ZI to  ZV zoeal  stages.
                                         31

-------
for metabolic compensation was much wider for the third through seventh
stage larvae.  In the fourth stage compensation extended to warmer tempera-
tures than in the earlier stages.  The fourth stage showed no compensation
from 10-25 C and compensated from 25-35 C.  The fifth stage was the reverse.
In the eighth stage, compensation occurred between 15-20 C and 25-30 C.  At
the extreme warm temperatures of 30-35 C, the metabolic rate of the third,
sixth, and eighth stages was depressed.

Larvae Cultured at Daily Cyclic Temperatures

     Oxygen consumption rates of the developmental stages of C_. irroratus
cultured at the constant 15 C and 10-20 C daily cyclic temperatures were
different at some of the test temperatures.  These differences in rate were
significant  (p<0.0l) for only first and second zoeal stages and the first
crab stage at 15 C.  At the 20'and 25 C test temperatures, almost all stages
from the cyclic regime respired faster than those from constant culture temp-
erature.  No obvious correlation of the variation of oxygen consumption rates
with the st&ge of-development was evident.
  VIII


  VII


  VI
UJ

K  V
V)


<  'V

<  III
_i

   II


   I
                                             C. borealis
                                              .o
                                              KQ|0<2
                                                        D

                                                        72
                   0   5   10  15  20  25 3O  35

                               TEMPERATURE,C

 Figure 17.   Metabolic-temperature  responses  (as  QJ_Q  values)  of larval  stages
 of C_.  borealis and P_.  pugio cultured at constant 20°C and 30 o/oo  salinity.

      Larvae of C.  irroratus cultured at 10-20 C  daily cyclic temperatures had
 different metabolic-temperature response patterns from those larvae  from con-
 stant  15 C  as reflected in the temperature range of  sensitivity (Q]_g>2), com-
 pensation (1
-------
                  VI
                UJ
                V)
                i
                or
                   IV
                   I
                                  v//
     C. irroratus
     CYCLIC
     CONSTANT
r.c   Qio>2
     KQ|0<2
                                                       D
                                                       0
                           i	I
                    0   5  IO  15  20 25  30
                                 TEMPERATURE, C

Figure 18.  Metabolic-temperature responses (as Qip values) of larval stages
of £. irroratus cultured in 3C o/oo at constant 15 C and cyclic 10 -20 C.

Larvae experiencing the daily cyclic temperature regime exhibited an exten-
sion of the temperature range for compensation, with a shift towards the
higher temperatures.  Oxygen consumption rate for larvae cultured with cyclic
temperatures was higher than those from constant temperatures at warmer test
temperatures.  The temperature, range for depression of metabolic rate shifted
from 20-25 C range for constant larvae to 25-30 C range for the cyclic larvae.

     Larval stages of the American lobster, H_. americanus, cultured at 15-25C
and 17.5-22.5 C daily cyclic temperatures and constant 20 C also showed inter
and intra-stage variation in their metabolic-temperature response patterns
(Fig. 19).  Larvae cultured at constant 20 C showed no compensatory response
of metabolic rate in the first larval stage, but compensatory response was
observed between 15-25 C for the second stage, 10-15 C for the third stage
and 15-25 C for the fourth stage.  Metabolic rate of the first and third
stage larvae was depressed between 20-30 C, compared to the 25-30 C range
for the second and fourth stages.  Culture at the daily cyclic regimes has
altered the metabolic-temperature response patterns of the larval stages rel-
ative to those at constant temperature.  These differences were reflected
in the zones of thermal sensitivity and compensation, but the pattern of
these changes were different for the larval stages.

     Larval stages of the estuarine grass shrimp, P_. pugio, cultured at 15-
25 C daily cyclic and 20 C constant temperatures showed both inter and intra-
stage variation in their metabolic responses to temperatures.  However, inter-
stage variation between the two culture regimes had no constant or predict-
able pattern (Fig. 20).  Culture at cyclic temperatures enhanced the res-
piration rate in some stages and reduced the rate in other stages.  First
stage larvae at the cyclic regime showed compensation between 10-15 C
                                     33

-------
                        CO
                            L4 i         L\x-:-:-:-;-;-;-:r->:-:-:--.-vv.-:-.y/////7771 20*C
                               Y////////A         E-X-.V:-:-:-.--xi•:•:• x-vX-XvH I5-25*C
                                                                     I7.5-22.5°C
                            L3 i->.'-x-Xyy.v:<        K/////////I/////////J
                        w      "/////////K-xx-XvXvM  /////// 1          i
                            1-2 i
                                        r/////////i
                           "  C
                               t         i-:-:-.Xv:vXvH         t////////7J
                               p--***y*-i	5-—^mnrm\
                               10        15       20       25       30
                                        TEMPERATURE  °C
Figure 19.  Metabolic-temperature responses (as Q   values)of  larval stages of Homarus americanus
cultured in 30  o/oo temperature-salinity  at constant 20 C and  cyclic 15-25 and 17.5-22.5~~c";

-------
and depression between 25-35 C ranges.   Metabolic rate of the second stage
was depressed over both the 10-15 and 30-35 C ranges,  with compensation be-
tween 25-30 C.  The third stage compensated between 10-15 C,  with depression
between 30-35 C.  For the fourth stage  metabolic rate  was compensated be-
tween 10-15 and 25-30C and depressed between 30-35 C.   The fifth stage com-
pensated over a broader range than the  earlier stages, i.e. between 20-35 C.
The sixth stage compensated between 15-25 C and has depressed between 30-35C.
In the seventh stage metabolic rate compensation was observed between 15-20
and 25-30 C and depresssion between 30-35 C.  The eighth stage larvae com-
pensated between 10-20 and depression occurred between 25 and 35 C.   Larval
stages cultured at constant 20 C showed equally variable metabolic tempera-
ture responses as those at the daily cyclic regime.
                         10   15   20   25   30   35
                             TEMPERATURE °C
Figure 20.  Metabolic-temperature responses  (as  QJ_Q  values)  of  larval  stages
of Palaemonetes pugio cultured in 30 o/oo salinity at  constant  20 C and
daily cyclic 15-25 and 17.5-22.5 C temperatures.
                                    35

-------
FATTY ACID METHYL ESTERS

     Fatty acid methyl esters were determined for the developmental stages
of C_. irroratus beginning with eggs to post-larvae cultured at constant 15 C
and H. americanus cultured at constant 20 C and 15-25 daily cyclic tempera-
tures.  In general, the fatty acid methyl esters in the developmental stages
of both species showed minor qualitative differences, except for the presence
of detectable amounts of 14:0 and 22:5 chain length fatty acids in C_.
irroratus (Table 11).

     Fatty acids  16:0, 16:1, 18:1, 20:5 and 22:6 were present in higher
concentrations than 14:0, 18:0, 20:1 and 20:4 and 22:5 in the eggs of C_.
irroratus.  In the succeeding larval stages, the fatty acrlds  16:0 and 20:5
remained  at a fairly constant concentration, while 22:6 decreased from a
high concentration in the eggs and first zoeae to low levels in the later
megalops  and crab stages.  Fatty acids  18:2 and 18:3 were observed in only
trace amounts in eggs and first zoeae, but they increased to detectable
amounts in the megalops and crab stages.  The 22:5 chain length fatty acid
present in detectable amount in eggs and first stage zoeae decreased to
trace amounts in the megalops and crab stage.

     In H_. americanus cultured at constant 20 C, fatty acids  16:0 and 18:1
were present in high concentrations and 16:1, 18:0 and 20:4 in low concen-
trations  through all the developmental stages from eggs to post-larvae.
20:5 and  22:6 chain length fatty acids were initially present in high con-
centrations in eggs and first larval stage then decreased progressively with
development to the post-larval stage.  Fatty acid chain lengths 18:2 and 18:3
in trace  amounts in eggs and first larval stage increased to detectable a-
mounts in the later stages of development, while 20:1 in high concentrations
in the eggs and first stage decreased beginning with the second stage.

      In H_. americanus cultured with 15-25 C daily cyclic temperatures, the
16:1, 18:1 and 20:5 chain length fatty acids were present in fairly high
concentrations through all stages beginning with eggs to the post-larvae.
Fatty acids  16:1, 18:0 and 20:4 were in low concentrations through all the
stages of development.  Initially high concentrations of 22:6 fatty acid in
eggs  steadily decreased with the progress of development to the post-larval
stage, whereas 18:2 and 18:3 were present in only trace amounts in the eggs,
then  increased to  detectable amounts beginning with the first larval stage.
Fatty acid 20:1 was present in detectable amounts in the eggs, then de-
creased to trace amounts beginning with the first larval stage.

      A comparison  of fatty acid methyl esters in E_. americanus larvae cul-
tured at  constant  and daily cyclic temperatures showed that certain fatty
acids had a tendancy for greater unsaturation under fluctuating thermal re-
gime  in some stages of development  (i.e.  16:0).  The other difference  ob-
served was an increase of certain fatty acids present in only trace amounts
at constant temperature to detectable amounts in those cultured under cyclic
temperatures  (i.e.  18:2 and 18:3).  Fatty acid (i.e.  20:1), present in only
detectable amounts in H_. americanus cultured at constant 20 C, were only pre-
sent  in trace amounts in those under cyclic regime.                       ^


                                     36

-------
  TABLE  11.   FATTY ACID METHYL ESTERS IDENTIFIED IN DEVELOPING  LARVAL STAGES
  OF  HOMARUS AMERICANOS CULTURED AT CONSTANT 20 C AND 15 -  25 C CYCLIC
  TEMPERATURES
                                      Chain length

   Stage         16:0   16:1   18:0    18:1   18:2   18:3   20:1    20:4    20:5   22:6
Eggs
I

II


III


IV

20 -H
15-25 -H
20 C -H
15-25 -H
20 -H
15-25 -H
20 -H

15-25 -H
20 -H

15-25 -H
•+ -H- -H- »-H- T T 1+
•+ -H- -HI- 4-H- T T -H-
-f '-H- -H- +H- T T -H-
-H -H- -H- +H- -H- +1- T
•+ -H- -H- -H-f +4- ++ T
-+ -H- -H- 1-t-h -H- -H- T
-+ -H- -H- -»-H- -H- +t- T

•+ -H- -H- H+f -H- -H- T
+ -H- -H-* +++ -H- -H- T

+ -H- HH- +++ ^-f -H- T
•1-f -H+ t-H-
-H +++ -H-+
+h -H+ +H-
-H- -»-»+ -m-
-H- H-H- -H-
-H- +++ -t-H
•H- -H- -H-

-H- -HH- -H-
-H- HH- -H-

-H- -»-H- ^-^
   •H-H Indicates above 10X, -H- leaa than 10% and T trace amounts per gram dry weight
ENZYME ACTIVITIES

     The potential influence of constant vs.  daily cyclic  temperatures on lar-
vae was examined "by assaying the  specific  activities  of lactate dehydrogenase,
malate dehydrogenase and glucose-6-phosphate  dehydrogenase in larvae of C_. ir-
roratus cultured at the 10-20 C cycle and constant  15 G   Activity of the three
enzymes was  higher in  the  first zoeae  and  the later larval stages than in the
intermediate stages for both culture regimes  (Fig. 21).  However, activity
of the three enzyme systems was affected differently by the cyclic tempera-
tures for the larval stages.   Lactate  dehydrogenase activity was enhanced
in the third and fifth zoeal stages and megalops stage at  10-20 C cycle com-
pared to that in larvae at 15  C.   The  activity of lactate  dehydrogenase was
significantly increased in the megalops stage compared to  that of the earlier
zoeal stages, regardless of temperature regime (Table 12).  The changes in
lactage dehydrogenase  activity in the  present study probably reflect changes
in overall glycolytic  activity during  larval  development.   LDH activity in
larvae cultured at cyclic  regime was substantially higher at the last two
stages (Table 12).  The malate dehydrogenase  activity decreased in all except
the fifth zoeal stage  at 10-20 C  cycle compared to that in larvae at 15 C.
The glucose-6-phosphate dehydrogenase  activity decreased in the second and
third stage  zoeae, but increased  in the fourth and fifth zoeal and megalops
stages at the cyclic regime.
                                     37

-------
             GLUCOSE
             ~P DEHYDROGENASE
         KJ3

        f
        1
      II

LACTATE
DEHYDROGENASE
           t 0.124
                                      CONSTANT !5°Co

                                      CYCLIC 10-20 °C«

                                      MALATE
                                      DEHYDROGENASE
             zi  zn zni ziv zv
                   zi  zn  zni  ziv  zv  M
                 LARVAL STAGE
                                     ZI  Zll  Zltl  ZIV ZV  M
Figure 21.  The effects of daily cyclic and constant temperatures on the
activities of lactate dehydrogenase, malate dehydrogenase and Glucose-6-
Phosphate dehydrogenase in Cancer irroratus larval stages cultured at con-
stant 20 C and 10-20 C daily cyclic temperatures.
TABLE 12.  ACTIVITIES OF LACTATE DEHYDROGENASE DETERMINED FROM CRUDE
           CELL-FREE HOMOGENATES OF CANCER IRRORATUS LARVAE CULTURED
           UNDER CYCLIC AND CONSTANT TEMPERATURES.   ACTIVITY IS EX-
           PRESSED IN id MOLES NADH GKIDIZED/MIN PER MG LOWRY PROTEIN.
           ASSAY TEMPERATURE WAS 15C-
State
Constant 15C
     Cyclic 15-20C
Cyclic/constant
Zoea-I
Zoea-II
Zoea-III
Zoea-IV
Zoea-V
Megalops
71.2
U6.1
38.8
50.2
51.6
95.1
58.6
2U.5
56. U
35.8
103.7
119.7
0.82
0.53
1.U5
0.71
2.01
1.26
                                     38

-------
ACUTE TEMPERATURE AND  LOW  DISSOLVED  OXYGEN TOLERANCES

     Tolerance limits  to acute  temperature, alone and in combination with low
dissolved oxygen stresses  were  determined for five zoeal stages and the meg-
alops of Cancer irroratus.   Temperature  tolerance at saturated dissolved
oxygen levels varied with  stage,  with this variation dependent on exposure
time (Fig.  22).  Little interstage variation was observed for the 120 minute
time interval, with all stages  having an LD,-n for temperature of about 29 C
(Table 13).  For a 240 minute   exposure, there was an overall decline in
tolerance and more interstage variation.  The second and fourth zoeae were
slightly more tolerant (28.2-28.5 C),  Vhile the others were less tolerant
(27,.2-27.5)  (Table 13).  No  significant  correlation was found between stage
and temperature tolerance  to indicate that there was a continuous relationship
between morphologically distinct  stages  and temperature tolerance.
                        U 29
                        S
                        UJ 28
                          27
                          26
                          25
                               I-;  2-Z  3-Z  4-Z  5-Z

                                  LARVAL STAGE
Figure 22.  Cancer irroratus.
           .Effect of larval stage on LD   values for
             	~—~~~~~^~~—~~                              50   —   	
temperature.  Open circles: 120 min exposure; filled circles: 240 min ex-
posure.  1-5Z; Zoeal stages; M: megalops.
TABLE 13.  CANCER IRRORATUS.  LD   VALUES FOR TEMPERATURE FOR 120 MIN AND
240 MIN EXPOSURE TIMES, BY STAGE.  NO STATISTICALLY SIGNIFICANT CORRELATION
WAS FOUND BETWEEN LD
URATED LEVELS IN ALL
   AND STAGE.  OXYGEN CONCENTRATIONS WERE KEPT AT SAT-
5#ESTS
               Stage
          IiD5o temperature (°C)
,
1
2
3
4
5
Megailops
120 min
29.0 ± 0.2
29.0 ± 0.02
29.0 ± 0.1
28.9 ± 0.1
29. O ± 0.3
29. O ± 0.01
24O min
27.5 ± 0.1
28.2 ± 0.1
27.5 ± 0.1
28.5 ± 0.2
27.5 ± 0.2
27.2 ± 0.2
                                     39

-------
     Larvae exhibited interstage variation in their pattern of response to
low dissolved oxygen tolerance over the experimental temperature range (Fig.
23).  The first, second and fourth zoeae showed a different pattern of re-
sponse, with an increase in tolerance from 10 to 15 C and a decrease from
15 to 30 C (Fig. 23).  Tolerance limits were maximum when the test tempera-
ture was the same as culture temperature (Fig. 24).  This pattern was con-
sistent for both the 120 and 240 min time intervals, with a tendency for
lower tolerance limits for the longer time intervals.
                                            2Z
                                 3Z
 :"^    'P
  i   i- _   I   i   I    nL_
                                                              M
                10     20     30  10     20     30      10
                              TEMP ERATUR E,  "C
                           20     30
Figure  23.  Cancer  irroratus.
 Effect of temperature on LD5n value of oxygen
Curves computed from regression equations ex-
for different larval stages.
cept for megalops  (M); Dots: 120 min exposure  (solid line); crosses: 240 min
exposure (dashed line).  1-5Z: Zoeal stages.
      The megalops  stage  showed  the  least  temperature-dependent  low dissolved
 oxygen tolerance (Fig. 23).   Tolerance  decreased  from  10-30  C;  however, the
 slope was slight compared to  that of other  stages.   There was no  significant
 difference in tolerance  as exposure time was increased from 120 to 240 min-
utes.  Regression analysis did  not yield any statistically significant re-
 lationship with  temperature.

      A comparison  between larval stages showed  the megalops  was least  toler-
 ant at most test temperatures (Figs.  23 6 24).  There  was interstage varia-
 tion in tolerance  from 10 to  20 C,  however.  At the  extremes of 25 and 30  C,
 little difference was observed between stages.   At 10 C,  the  first, second
 and fourth zoeal stages  showed  higher tolerance than the other  stages.  At 15
 C,  the third stage was most tolerant, while at  20 C, the fourth was the most
 tolerant.  No statistically significant correlation  of tolerance  with  stager
 was found using  either l/LD,-n = (stage  number)  +  B or  log 1/LD5Q  = a  (stage

                                     40

-------
number) + b.
 
-------
tolerated slightly higher temperatures and the megalops  lower  temperatures
than the other stages.  It would appear that although  certain  stages  in the
larval development of a species may be slightly more resistant or  sensitive
to temperature, the general temperature tolerance  limits for overall  devel-
opment remains the same for a  species and is related to  the temperature
range of their habitat.
                  38 r
               o
                c 34
                O
                n
               Q
                ~, 30
                  26
                                              P. pugio
                                      H. amer/canus
                                            C. irroratus
                                   \
                                   345
                                 LARVAL STAGE
 Figure 25.  Acute temperature tolerance limits for three species of crus-
 taceans cultured under constant conditions optimal for their survival.  C.
              O                                            O             ~~
 irroratus, 15 C - 30 o/oo;  H. americanus and P. pugio, 20 C - 30 o/oo.

-------
                                SECTION 6

                                DISCUSSION
     Larvae of epibenthic Crustacea play an important role in the distribu-
tion, gene exchange, pelagic food web and recruitment of young to the adult
populations.  Generally, larvae are released into the pelagic environment
when conditions are optimal for their development and growth.  During their
pelagic existence larvae are exposed to continuously varying temperatures
along with other fluctuating environmental parameters.  Larval development
occurs within a range of environmental conditions which is characteristic
to each species.  Interaction of environmental parameters can affect larval
development as reflected in varying survival and developmental rates when
cultured under different combinations of temperature and salinity (Costlow
and Bookhout, 1964; Sastry and Vargo, 1977).  A species may exhibit an opti-
mal survival with a given combination of conditions.  Then as environmental
conditions deviate from this optimum, survival rate is reduced.  Limits, as
well as the optimal combination for development, vary interspecifically.  In
the present study, the coastal species (high salinity) completed development
over a narrower range of temperature and salinity than the predominantly es-
tuarine species.  These limits varied from a single temperature and salinity
combination, as seen with C_. borealis, to a wide range of suitable tempera-
ture and salinity conditions as occurred with P_. longicarpus and P_. pugio.
Limits for complete development may also be a function of the environmental
history of the eggs prior to their hatching.  Larvae of C. irroratus hatched
from eggs incubated during the period they are normally released in nature
survived in laboratory culture better than those hatched at other seasons.
It appears then that stage of embryonic development at which the eggs are
incubated for hatching and their previous thermal history will affect the
survival rate, and the limits for complete development.

     In addition to these variations, larvae of C.. irroratus cultured under
constant and daily cyclic regimes also differed in their survival and time
required for complete development.  Those cultured under a suitable ampli-
tude and rate of temperature change showed an increase in survival compared
to those at comparable constant temperatures.  Beyond these limits, as with
the 15-25 C cylce for C_. irroratus, larval development was delayed compared
to that at constant 20 C.  The affects of daily cyclic and constant tempera-
tures on survival and development time also varied inter-specifically.  The
estuarine grass shrimp, P_. pugio larvae showe'd no significant differences in
either the duration of development or survival at daily cyclic and comparable
constant temperatures.  Clearly, the affects of fluctuating temperatures
from observations on one species should not be generalized for others.

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     Larvae of geographiqally separated populations may also exhibit dif-
ferences in their survival and time required for complete development.  For
example, larvae of R_. harrisii from the New England region developed more
slowly than those from, southern geographical regions at somewhat similar
temperature and salinity combinations.  In contrast, the larvae of geograph-
ically separated populations of II. americanus and P_. pugio showed no pro-
nounced differences in their developmental time at somewhat similar compara-
ble culture conditions (.Table 6 and 7).  A comparative assessment of lati-
tudinal  population differences in the effects of temperature and other en-
vironmental factors on larval development and survival would be necessary in
utilizing the present results for water quality criteria purposes.

     Within the tolerance range of a species, metabolic rate may vary rela-
tive to temperature, but each species usually has a characteristic overall
response.  For example, C_. irroratus larvae showed a narrowing of the temp-
erature range for metabolic compensation (1
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(Sastry and Ellington, 1978).

     Acute temperature tolerance limits varied intra- and inter-specifically
with estuarine species tolerating higher temperatures than the coastal
species under saturated oxygen conditions (Sastry and Vargo, 1977)•   These
limits remained fairly constant for all C_. irroratus larval stages;   some
II. americanus and P. pugio stages showed differential sensitivity.   However,
when low dissolved oxygen and temperature stress were combined more inter-
stage variation was evident with C_. irroratus.

     The metabolism, development and growth and survival of larvae  may vary
with stage, season of hatching, culture conditions, and geographic  origin of
the population.  These intra-specific variables have to be taken into con-
sideration in the application of laboratory bioassay results for the eval-
uation of the potential effects of thermal and other pollutants on  a natural
population or community.

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                                SECTION 7

                                REFERENCES
Alderice, D. F. Factor combination.  In:  Marine Ecology, Vol. 1, Pt. 3.
     Wiley-Intersceince, New York, 1972.  pp. 1659-1722.

Bliss, C. I.  The statistics of bioassay.  Academic Press, N.Y., 1952. 628 pp.

Borad, A. C.  Larval development of Palaemonetes pugio.  Holthius.  Biol.
     Bull., 112: lUU-161, 1957-

Bullock, T. H.  Compensation for temperature in the metabolism and activity
     of poikilotherms.  Biol. Rev., 30: 311-3U2, 1955.

Carritt, D. E. and J. H. Carpenter.  Comparison and evaluation of currently
     employed modification of the Winkler method for determining dissolved
     oxygen in sea water, a NASCO report, J. Mar. Res., 2k: 286-318, 1966.

Clark, J. R.  Thermal pollution and aquatic life.  Sci. American, 220: 19-
     27, 1969.

Connoly, C. J.  The larval stages and megalops of Rhithropanopeus harrisii.
     pish. Res. Bd. Canada, Contributions to Canadian Biology and Fisheries,
     N 2: 329-337, 1925.

Costlow, J. D. and C. G. Bookhout.  An approach to the ecology of marine
     invertebrate larvae.  Symp. Expt. Ecol., Grad. Sch. Oceanography,
     Occassional Publ., No. 2, 196U.  pp. 69-75.

Costlow, J. D. and C. G. Bookhout.  The effects of cyclic temperatures on
     development in the crab, Rhithropanopeus harrisii.  In: kth European
     Symp. Mar. Biol., D. J. Crisp, ed.  Cambridge Univ. Press, Cambridge,
     Mass., 1971.  pp. 211-220.

Costlow, J. D. and C. G. Bookhout and R. Monroe.  Studies on the larval
     development of the crab, Rhithropanopeus harrisii (Gould).  I. The
     effect of temperature and salinity on larval development.  Physiol.
     Zool., 39: 81-100, 1966.

Goutant, C. C. and S. S. Talmage.  Thermal effects.  J. Water. Poll. Cont.
     Fed.,  U9: 1369-1^25, 1977.

Esch, G. W. and R. W. McFarlane.  Thermal ecology II. Conf. 7502^25.  ERDA
     Symposium Series, No. Uo, Tech. Infor.  Center, ERDA, 1976. UoU pp.     ^

                                    U6

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Gibbons, J. W. and R. R. Sharitz.  Thermal ecology.  Conf. 730505, U.S.
     Atomic Energy Commission, 1974.  670 pp.

Goldstein, A. 1964.  Biostatistics:  An introductory text.  272 pp.  The
     McMillan Co., New York, 1964.  272 pp.

Gunter, G.  Temperature, Chapter 8.  Geol. Soc. America, Memoir 67, 1:159-184.
     1957.

Hadley, P. B.  Additional notes upon the development of the lobster.
     Fourtieth Ann. Rep. Commissioners Inland Fish. Rhode Island, E. L.
     Freeman Co., Providence, R.I., 1909.

Hargis, W. J. and J. E. Warinner.  Impact of thermal alterations on estuarine
     and coastal environments.  Program on thermal considerations in the
     production of electric power, Atomic Industrial Forum Inc., and Electric
     power council on environment, Washington, D. C. 1970.  53 pp.

Hazel, J. R. and C. L. Prosser.  Molecular mechanisms of temperature com-
     pensation in poikilotherms.  Physiol. Rev., 54: 620-677, 1974.

Herrick, F. H.  The habits and development of the lobster and their bearing
     upon its artificial propagation.  Bull.  U.S. Fish. Comm. 13:  75-86,
     1894.

Hughes, J. T. and G. C. Matthiessen.  Observations on the biology of the
     American lobster, Homarus americanus.  Limonl. Oceanogr. 7: 4l4-421,
     1962.

Jensen, L. D., R. M. Davies, A. Brooks and C. D. Meyers.  The effects of
     elevated temperature on aquatic invertebrates.  Edison Electric Inst.,
     Res. Project No. 49.  The John Hopkins Univ., Baltimore, 1969. 232 pp.

Kinne, 0.  The effect of temperature and salinity on marine and brackish
     water animals.  I. Temperature.  Oceanogr. Mar. Biol., Ann. Rev.,  1:
     301-340, 1963.

Kinne, 0.  The effect of temperature and salinity on marine brackish water
     animals.  II.  Salinity and temperature-salinity combinations.  Oceanogr.
     Mar. Biol. Ann. Rev., 2: 101-339, 1964.

Kinne, 0.  Temperature, animals, invertebrates.  In:  Marine Ecology, 0.
     Kinne, ed. Wiley-Interscience, London, 1970.  pp.  407-514.

Krenkel, P. A. and F. J. Parker.  Biological aspects of thermal pollution
     Vanderbuilt Univ. Press., Nashville,  Tenn. 1969.

Meleikovsky, S. A.  The influence of pollution on pelagic larvae of bottom
     invertebrates in marine nearshore and estuarine waters.   Mar.  Biol.,
     6:  350-356, 1970.
                                    47

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Nylor, E.  Effects of heated effluents upon marine and estuarine organisms
     Adv. Mar. Biol., 3: 63-103, 1965-

Prosser, C. L.   Temperature.  In: Comparative Animal Physiology, C. L.
     Prosser, ed.  Saunders, Philadelphia, Pa., 1971.  pp.. 362-1*28.

Roberts, M. H.   Larval development of Pagurus longicarpus Say reared in
     the laboratory, I. Description of larval instars.  Biol. Bull., 139:
     188-202, 1970.

Sastry, A, N.  Culture of "brachyuran crab larvae using a recirculating sea
     water system in the laboratory.  Helgolander wiss. Meeresunters, 20:
     1*06-1*16, 1970.

Sastry, A. N.  Effects of constant and cyclic temperature regimes on the
     larval development of a brachyuran  crab.  In:   Second Termal Ecol.
     Syjup. G. W. Esch and R. W. McFarlane, eds.  ERDA Symp.  Ser., ('Conf.
     750U25), 1*0: 81-87, 1976.

Sastry, A. N.  Larval development of the rock crab,  Cancer irroratus Say
     1817, under laboratory conditions  (Decapoda, Brachyuran).   Crustaceana,
     32:  155-168, 1977a.

Sastry, A. N.  Physiiological adaptation  of Cancer irroratus  larvae to cyclic
     temperatures.   In:  Physiology and  Behavior of  Marine Organisms.
     D.  S. McLusky and A. J. Berry, eds. Pergamon Press, Oxford, 1978.
     pp.  57-65.

Sastry, A. N. and W. R. Ellington.  Lactate  dehydrogenase during the larval
     development of  Cancer  irroratus;  Effect of constant and cyclic thermal
     regimes.  Experentia,  3^:  308-309,  1978.

Sastry, A. N. and J. F. McCarthy.  Diversity of metabolic adaptation of
     pelagic  larval  stages  of two  sympatric  species  of brachyuran crabs.
     Neth. J. Sea Res., 7:  43U-UU6, 1973.

Sastry,  A. N. and S. L. Vargo.  Variation  in physiological responses of
      crustacean larvae to temperature.   In:  Physiological responses of
     marine biota to pollutants.   F. J.  Vernberg, A. Calabrese,  Thurberg
      and ¥. B. Vernberg,  eds.   Academic  Press, New York, 1977.   pp. 1*01-1*23.

Scarratt, D.  J.   Distribution  of  lobster larvae  (Homarus americanus) off
     Pictous, Nova  Scotia.  J.  Fish. Res.  Bd. Canada, 25: 1*27-1*30 pp.,1968.

Sherman,  K. and R.   D.  Lewis.   Seasonal  occurrence of larval lobsters in
      coastal  waters  off central Maine.   Proc. Nat. Shellfish, Assoc.
      57:  27-30, 1967.

Templeman, W.  The  influence of temperature, salinity, light and food con-
      ditions  on the survival and  growth of the larvae of the lobster
      (Homarus americanus).  J.  Biol. Bd. Canada, 2:  485-1*97, 1937.


                                     1*8

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Thorson, G.  Reproduction and larval ecology of marine bottom invertebrates
     Biol. Rev., 25: 1-^5, 1950.

Vargo, S. L. and A. N. Sastry.  Acute temperature and low dissolved oxygen
     tolerances of brachyuran crab (Cancer irroratus) larvae.   Mar. Biol.,
     UO: 165-171, 1977-

Vernberg, F. J. and W. B. Vernberg.   The animal and the environment.   Holt,
     Reinhart and Winston, New York, 1970.  398 pp.

Vernberg, W. B. and F. J. Vernberg.   Environmental physiology of marine
     animals.  Springer-Verlag, New York, 3^6 p.  1972.

Wieser, W.  Effects of temperature on ectothermic organisms,  ecological
     implications and mechanisms of compensation.  Springer Verlag, New York,
     1973. 298 pp.

Williams, A. B.   Marine decapod crustaceans of the Carolinas.   Fishery
     Bulletin, Vol. 65 (l): 1-290, 1965.

-------
                                 SECTION 8

                                PUBLICATIONS
     Listed are publications and papers presented from the work completed
with partial or full support of Grant R-800981.

Sastry, A. N.  Metabolic adaptation of brachyuran crab larvae cultured under
     constant and cyclic temperature regimes.  Am. Zool., 15: 749, 1975-

Sastry, A. N.  Temperature variation and physiological responses of crusta-
     cean larvae.  Joint Oceangr. Assembly, Edinburgh, U.K. Abstract, 1976,
     P 152.

Sastry, A. N.  Effects of constant and cyclic temperature regimes on the
     larval development of a brachyuran crab.  In: Second Thermal Ecol. Symp.
     G-. W. Esch and R. W. McFarlane, eds., ERDA Symp. Series (Conf. 750425).
     40: 81-97, 1976.

Sastry, A. N. and John Laczak, 1976.  Metabolic adaptation of Palaemonetes
     pugio larval stages cultured at constant and cyclic temperature regimes.
     Am. Physiol. Soc., Ann. Meeting, Philadelphia (Abstract).

Sastry, A. N.  Larval development of the rock crab, Cancer irroratus Say
     l8l7, under laboratory conditions (Decapoda, Brachyura).  Crustaceana,
     32: 155-168, 1977.

Sastry, A. N.  Larval development of the Jonah crab, Cancer borealis Stimpson,
     1859, under laboratory conditions (Decapoda, Brachyura). Crustaceana,
     32: 290-303, 1977-

Sastry, A. N. and S. L. Vargo.  Variation in the physiological responses of
     crustacean larvae to temperature.  In:  Physiological responses of mar-
     ine biota to pollutants, F. J. Vernberg, A. Calabrese, B. Thurberg and
     ¥.'B. Vernberg, Academic Press, New York, 1977, pp. 401-1*23.

Vargo, S. L. and A. N. Sastry.  Acute temperature and low dissolved oxygen
     tolerances of brachyuran crab  (Cancer irroratus) larvae.  Mar. Biol.,
     40: 165-171, 1977.

Sastry, A. N. and Jan Pechenik.  A review of the ecology, physiology and be-
     havior of lobster larvae (Homarus americanus and H.. gammarus).  Div.
     Fish. Oceanogr. Circ. 7, Commonwealth Scientific and Industrial Research
     Org. Australia, pp. 159-173.


                                      50

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Sastry, A. N.  Physiological adaptation of Cancer irroratus larvae to cyclic
     temperatures.  In Physiology and Behavior of Marine Organisms, D. S.
     McLusky and A. J. Berry, eds.  Pergamon Press, Oxford, 1978? PP- 57-65-

Sastry, A. N. and W. R. Ellington.  Lactate dehydrogenase during the larval
     development of Cancer irroratus:   Effect of constant and cyclic thermal
     regimes.  Experentia, 3^: 308-309, 1978.

Sastry, A. N.  Metabolic adaptation of Cancer irroratus developmental stages
     to cyclic temperatures.  Mar. Biol. 51:   2k3-250, 1979-

Sastry, A. N.  Effects of temperature on the larval development of Crustacea.
     In: Reproduction and growth in Marine Invertebrates (Ed. V. L. Kasyanov),
     XIV Pacific Science Congress.  In Russian (in press).
PAPERS PRESENTED AT SCIENTIFIC MEETINGS

Sastry, A. N.  Effects of constant and cyclic temperature regimes on the
     larval development of a brachyuran crab.  Second Thermal Ecol.  Symposium,
     Augusta Georgia, April 2-5, 1975-

Sastry, A. N.  Metabolic adaptation of pelagic larvae of a crustacean to
     constant and cyclic temperatures.  Ann.  Meeting, AIBS, Corvallis,
     Oregon, August 17-23, 1975-

Sastry, A. N. and S. L. Vargo.  Tolerance of  Cancer irroratus and Palaemonetes
     pugio larval stages to acute temperature and low dissolved oxygen.   38th
     Ann. Meeting, Am Soc. Limnol. Oceanogr., Halifax, Canada, June  22-27,
     1975.

Sastry, A. N. and S. L. Vargo.  Variation in  physiological responses of
     crustacean larvae to temperature.  Pollution and physiology of  marine
     organisms, Symposium, Milford, Conn. November U-6, 1975.

Sastry, A. N. and John Laczak.  Metabolic adaptation of estuarine grass
     shrimp, Palaemonetes pugio larvae cultured at constant and cyclic temp-
     eratures.  Am. Soc. Physiol., Ann. Meeting, Philadelphia, Pa. August,
     1976.

Sastry, A. N.  Temperature variation and physiological responses of  crusta-
     cean larvae.  Joint Oceanogr. Assembly,  Edinburgh, U.K., September  12-
     24, 1976.

Sastry, A. N.  Physiological adaptation of Cancer irroratus larvae to cyclic
     temperatures.  12 European Symp.  Mar.  Biol. Stirling,  Scotland,  U.K.,
     Sept. lt-13, 1977.

Sastry, A. N.  Physiological adaptations in reproduction and larval  develop-
     ment of coastal and estuarine organisms,  U.S. - USSR meeting on
     Physiology and Biochemistry of marine organisms.   Georgetown, S.C.,  Oct.
     6-10, 1977.

                                     51

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Sastry, A. N.  Metabolic adaptation of developing larvae of Crustacea to the
     varying thermal environment.  XIV Pacific Science Congress,  Khabarovsk,
     USSR, August 20- September 1, 1979.

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                                   TECHNICAL REPORT DATA
                            (Please read Instructions on the reverse before completing)
1. REPORT NO.
  EPA-600/3-80-064
                                                           3. RECIPIENT'S ACCESSION»NO.
4. TITLE AND SUBTITLE
  Effects of Thermal Pollution on Pelagic Larvae of
  Crustacea
                        5. REPORT DATE
                             JULY 1980
  ISSUING DATE.
                        6. PERFORMING ORGANIZATION CODE
7. AUTHOR(S)
  A. N. Sastry
                                                           8. PERFORMING ORGANIZATION REPORT NO.
9. PERFORMING ORGANIZATION NAME AND ADDRESS
  Graduate School of  Oceanography
  University of Rhode Island
  Kingston, Rhode Island   02881
                                                           10. PROGRAM ELEMENT NO.
                        11. CONTRACT/GRANT NO.
                                                              R-800981
12. SPONSORING AGENCY NAME AND ADDRESS
                                                           13. TYPE OF REPORT AND PERIOD COVERED
  Env ironmental Research  Laboratory - Narragansett
  Office of Research and  Development
  U.S.  Environmental Protection Agency
  Narragansett, RI  02882
                        14. SPONSORING AGENCY CODE

                           EPA/600/05
15. SUPPLEMENTARY NOTES
16. ABSTRACT
           Larvae of  six  species,
Cancer irroratus,  C_.  borealis and Homarus americanus
                     jugio, Pagurus  longicarpus and
  of coastal waters  (high  salinity),  and Palaemonetes  	  	
  Rhithropanopeus harrisii,  from the estuarine region  (variable salinity) were studied.
  Larvae were cultured  at  various combinations of  temperature and salinity  and highest
  survival rates and  limits  for complete development determined.  Coastal species have
  a more restrictive  temperature range.  Thermal tolerance limits for larvae  of the
  primarily estuarine P_. pugio were higher compared to larvae of coastal species,.
  C. irroratus and H_. americanus.  When temperature and low dissolved oxygen  stresses
  were combined, thermal tolerance limits of C_. irroratus larvae were altered.   Sur-
  vival was better for  C.  irroratus larvae cultured under certain daily cyclic
  regimes vs. a constant temperature.  In contrast, larvae of P_. pugio showed no
  significant differences  in either survival or developmental rate when under cyclic
  vs. constant temperatures.
       Metabolic responses of C_. irroratus, tl. americanus and P_. pugio were determined
  for a series of temperatures.  Larvae of coastal C.  irroratus and E_. americanus were
  metabolically active  over  a narrow temperature range.  The estuarine species  P_.
  pugio and response  patterns of larvae cultured at cyclic temperatures differed from
  those at constant temperatures.  Differential effects of daily cyclic vs. constant
  temperatures also occurred in fatty acid methyl  esters in E_. americanus and in enzyme
          nf f*  i rrnratnc;  larvao 	  	         	
17.
                               KEY WORDS AND DOCUMENT ANALYSIS
                  DESCRIPTORS
                                              b.lDENTIFIERS/OPEN ENDED TERMS
                                      c.  cos AT I  Field/Group
  Crustacea
  Larvae
  Physiological Effects
  Temperature
  Salinity
  Oxygen
            Larval development
            Ljmiting factors
            Cyclic temperatures
            Estuarine
            Coastal
  06F
18. DISTRIBUTION STATEMENT


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