U.S. DEPARTMENT OF COMMERCE
                       National Technical Information Service

                       PB-255 852
Applicability of the Cyanide
Electrode for  Measuring Free
and Total  Cyanide
Central State Univ.
Prepared For
Environmental Monitoring & Support Lab.
June 1976

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                                   TECHNICAL REPORT DATA
                            (Please nod Imtnictioru on the rtvtrte before completing}
 REPORT NO.
   EPA-600/4-76-020
           3. RECIPIENT'S ACCESSION-NO.
 TITLE AND SUBTITLE
   The Applicability of  the Cyanide Electrode for
   Measuring Free and Total Cyanide
                                                            S. REPORT DATE
                                                                June 1976  (Issuing Date)
           6. PERFORMING ORGANIZATION CODE
 AUTHOR(S)

   Albert  Schlueter
           8. PERFORMING ORGANIZATION REPORT NO.
 . PERFORMING ORGANIZATION NAME AND ADDRESS

   Central State University
   Wilberforce, Ohio   45384
            10. PROGRAM ELEMENT NO.

                1HA323 and EHE62^
            11. CONTRACT/GRANT NO.

                R-802755-01
12. SPONSORING AGENCY NAME AND ADDRESS
    Environmental Monitoring and Support  Laboratory
    Office of Research  and Development
    U.S.  Environmental  Protection Agency
    Cincinnati, Ohio   45268
            13. TYPE OF REPORT AND PERIOD COVERED
            14. SPONSORING AGENCY CODE
                EPA-ORD
15. SUPPLEMENTARY NOTES
16. ABSTRACT
         The Orion model 94-06 cyanide  electrode was evaluated to determine its
    applicability to  water and wastewaters.   The calibration curve was Nernstian
    over the concentration range of  0.26 to 26 ppm, and  the slope of the  curve
    was 59 mv per decade change.  This  work consisted  in studying the response
    of the cyanide electrode to cyanide when this ion  was present in solution in
    both free and complex forms.  The results show conclusively that the  electrode
    responds only to  free cyanide in solution and not  at all to that complexed to
    metals.
17.
                                KEY WORDS AND DOCUMENT ANALYSIS
                  DESCRIPTORS
                                               b.lDENTIFIERS/OPEN ENDED TERMS
                            COSATi Field/Group
    Cyanides
    Water analysis
    Monitors
    Hydrogen cyanide
    Iron cyanides
Cyanide  electrodes
Free cyanide
                                 13B
18. DISTRIBUTION STATEMENT

    Release  to public
                                               10. SECURITY CLASS (This Report)
                                                                          21. NO. OF PAGcS
                                 29
                                               20. «CT/RTTY'C.C&SS (Thlj page)
                                                 Unclassified
                                                                          22. PRICE
EPA Form 2220-1 (t-73)
                                                                «USGPO: 1976 — 657.«95/5452 ««glon 5-11
                                                                  PRICES SUBJECT TO CHANGE

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                                       EPA-600/4-76-020
                                       June 1976
            APPLICABILITY OF THE
    CYANIDE ELECTRODE FOR MEASURING FREE
              AND TOT/i, CYANIDE
                     by

               Albert Schlueter
            Department  of Chemistry
           Central  State University
           Wilberforce, Ohio  45384
             Grant No.  R-802755-01
                Project Officer

                 Morris Gales
Environmental Monitoring and Support Laboratory
            Cincinnati, Ohio  45268
     U.S. ENVIRONMENTAL PROTECTION AGENCY
      OFFICE OF RESEARCH AND DEVELOPMENT
ENVIRONMENTAL MONITORING AND SUPPORT LABORATORY
            CINCINNATI, OHIO  45268

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                              DISCLAIMER

     This report has been reviewed by the Environmental Monitoring
and Support Laboratory, U.S.  Environmental Protection Agency,  and
approved for publication.  Approval does not signify that the  contents
necessarily reflect the views and policies of the U.S.  Environmental
Protection Agency, nor does mention of trade names or commercial
products constitute endorsement or recommendation for use.
                                   11

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                               FOREWORD

     Environmental measurements are required to determine the quality
of ambient waters and the character of waste effluents.   The Environ-
mental Monitoring and Support Laboratory-Cincinnati conducts research
to:

     o  Develop and evaluate techniques to measure the presence and
        concentration of physical, chemical, and radiological
        pollutants in water, wastewater, bottom sediments, and
        solid waste.

     o  Investigate methods for the concentration, recovery, and
        identification of viruses, bacteria, and other microbio-
        logical organisms in water.  Conduct studies to determine
        the responses of aquatic organisms to water quality.

     o  Conduct an Agency-wide quality assurance program to assure
        standardization and quality control of systems for monitor-
        ing water and wastewater.

     There is an ever-increasing interest in the use of electrode
methods to analyze water and waste samples, whether the resulting
data are  to be used for research,  surveillance, compliance monitoring,
or enforcement purposes.  Accordinaly, the Environmental Monitoring
and Support Laboratory has an ongoing methods research effort in the
development, evaluation, and modification of electrode procedures.
This particular report pertains to the evaluation of the cyanide elec-
trode.  The method has potential routine application for the analysis
of free cyanide in surface waters  and domestic and industrial wastes.
                                   Dwight  G.  Ballinger
                                        Director
                       Environmental  Monitoring  and  Support  Laboratory
                                  111

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                              ABSTRACT

     The Orion model 94-06 cyanide electrode was evaluated to deter-
mine its applicability to water and wastewaters.  The calibration
curve was Nernstian over the concentration range of 0.26 to 26 ppm,
and the slope of the curve was 59 mv per decade change.   This work
consisted in studying the response of the cyanide electrode to cya-
nide when this ion was present in solution in both free and complex
forms.  The results show conclusively that the electrode responds
only to free cyanide in solution and not at all to that complexed to
metals.
                                 IV

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                               CONTENTS




                                                                  Page
Foreword                                                            iii



Abstract                                                            iv



List of Tables                                                      vi




Acknowledgment                                                      vii






I    Introduction                                                    1




II   Surciuary                                                         2




III  Conclusions                                                     3




IV   Recommendations                                                 4




V    Experimental                                                    5




VI   Data                                                            7

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                             LIST OF TABLES

Number

  1   Stability Equilibrium Constants (Ks) and Rates              8
        of Ligand Exchange for Some Typical-Cyanide
        Complexes

  2   Response of the Cyanide Electrode to Metal-Cyanide          9
        Complexes at Different pH Values

  3   Relative Response in Millivolts of the Cyanide             10
        Electrode to Successive 1 ml Additions of 1.0 x
        10-3M Metal Ions to 100.0 ml of a 1.0 x 10'4M
        (2.6 ppm) Cyanide Solution

  4   Relative Millivolt Readings                                12

  5   Relative Response in Millivolts of the Cyanide             13
        Electrode to the Addition of Mickel  (11) and
        Copper (11) to Solutions Containing  Both EDTA
        and Cyanic?- (pH13)

  6   Relative Response in Millivolts of the Cyanide             14
        Electrode to the Dissociation of the Nickel-
        Cyanide Complex by EDTA at pH13

  7   Response of the Cyanide Electrode to the Cyanide           16
        Concentrations in Solutions Resulting From  Acid
        Hydrolysis-Distillation of Solutions of KCN and
        Metal Complexes

  8   Acid Hydrolysis-Distillation of Metal-Cyanide             16
        Complexes

  9   Effects of Metal Ions on the Recovery  of Cyanide           17
        With Acid Hydrolysis-Distillation

  10   Response of the Cyanide Electrode to the Cyanide            19
        Concentration in Several Natural  Samples Using
        Various Analysis Methods

  11   Electrode Response to  Solutions  Spiked with  Additional     19
        Cyanide  (Increased by  5  x  10"^M_)

  12   Analysis of  Fish  from  Fish Kill                             19
                                  VI

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                               ACKNOWLEDGMENT

     The work of Michael Taylor, a senior Chemistry major at Central
State University, in collecting much of the data contained in this
report is gratefully acknowledged.  The assistance of Gerald Pitts and
Ernest Lieis in the initial phase of this work is note.

     Also acknowledged is the considerable help of Morris Gales, Jr.,
Project Officer of this grant, and others at the Environmental Monitor-
ing and Support Laboratory in Cincinnati, Ohio, for clearly defining  the
scope of the work.  The assistance of Mr. Gales specifically and the
U.S. Environmental Protection Agency generally has supplied Central
State University faculty and students a valuable opportinity to partici-
pate in important and relevant research work.
                                   Vll

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                                 SECTION I
                               INTRODUCTION

     The classical cyanide determination uses acid-hydrolysis  to  convert
free and complexed cyanide into hydrogen cyanide,  which is  distilled
from solution for subsequent determination.  The result of  this analysis
thus gives the total amount of cyanide in solution (i.e.  both  free and
complexed cyanide).  It can be argued that for evaluation of environ-
mental impact, in most cases, the free cyanide levels are of more signi-
ficance than the total cyanide content.   Cyanide complexed  with ferrous
or ferric iron, for example, is both kineticly and thermodynamicly in-
ert, and thus, the complexed-cyanide has no business being  classified
with the free cyanide if the amount of chemically-active cyanide  is being
evaluated.  The important distinction between free and total cyanide
levels has not received sufficient attention by those doing cyanide
analyses or by those evaluating the results of cyanide determinations.
Though the classical hydrolysis-distillation cyanide determination was
only amenable to determinations of the total cyanide levels, the  recent
development of the cyanide-selective electrode makes measurement  of
free cyanide potentially feasible.  It is essential that the meaning  of
the cyanide concentrations measured with the cyanide electrode be care-
fully ascertained and their relationship to free and total  cyanide de-
termined.  Though the responses of the cyanide electrode to cyanide
levels in laboratory-prepared samples and its utility in the analysis of
many natural products have been amply reported, the meaning of the re-
sults as free or total cyanide remains ambiguous.  The purpose of this
report is to clarify the meaning of the cyanide electrode responses.
This study investigates the effect of metal-cyanide complexes  on the ion
selective electrode, the effects of metal-contaminats on the cyanide
electrode response, and the conditions under which the electrode can be
used to give evaluations of the free and total cyanide levels.

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                                 SECTION II
                                  SUKMARY

     The work presented here consisted of studying the response of the
cyanide electrode to cyanide when this ion was present in solution in
both free and complexed forms.   The results show conclusively that the
electrode responds only to free cyanide in solution and not at all to
that complexed to metals.  Nickel and copper are shown to form the most
stable complexes, and ferrous and ferric iron, zinc, and lead form less
stable complexes.

     Attempts were made to use the cyanide electrode to measure total
cyanide concentration (i.e. both free and complexed cyanide) by adding
a strong complexing agent to decompose the cyanide complexes.  Both
hydroxide and ethylenediamine tetracetic acid (EDTA) were investigated,
but the thermodynamic and kinetic stability of the cyanide complexes
rendered determination of total cyanide with the cyanide electrode
unfeasible.

     Studies with the cyanide electrode in the hydrolysis-distillation
procedure for determining total cyanide indicate that high metal  ion
concentrations can give  low results.  In light of this result and the
demonstrated kinetic and thermodynamic stability of the metal-cyanide
complexes, the environmental significance of determination of total
cyanide levels is questioned.   It is  suggested that determination of
free cyanide concentrations with the  cyanide elertrod0 T.lght be ,x>re
significant and  meaningful.

     Studies of  the  cyanide  levels  in natural water samples  are found
to  be  at the limit of Nernstian response of the cyanide  electrode.
Electrode  responses  s^em to  correlate with free cyanide  levels  even
though the determinations  contain  larger errors.

     The cyanide electrode  is used  to determine the cyanide  levels  in
two fish and one crayfish  that  died in  a  large fi^h kill.  Though an
effluent containing  cyanide  was suspected, this study indicates normal
cyanide levels.

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                                SECTION  III
                                CONCLUSIONS

     This work has demonstrated four things:

     1.   that the cyanide electrode responds  to free cyanide  levels  as
         opposed to the total  cyanide concentration in aqueous  solution;

     2.   th-ic a simple procedure for determining total cyanide  using
         the cyanide electrode is not feasible because of the great
         stability of metal-cyanide complexes;

     3.   that the classical acid hydrolysis-distillation procedure
         for determining total cyanide may not accurately yield true
         total cyanide levels  in the presence of large metal  ion con-
         centrations;

     4.   that the concentrations of cyanide in natural surface  water
         samples are at the limit of Nernstian response of the  cyanide
         electrode and beyond.

     The unusually great kinetic stability of metal-cyanide complexes,
even the very labile nickel-cyanide complex,  coupled with their great
thermodynamic stability renders determination of total cyanide  levels
with the cyanide electrode extremely unlikely.  Concomitantly,  this
exceedingly great stability brings to question the significance of de-
terminations of total cyanide.  This work indicates that evaluation  of
free cyanide, or perhaps cyanide freed by EDTA using the cyanide
electrode, might be the more significant measurement of the cyanide
content in water samples.  Such measurements  would more accurately re-
flect the level of chemically  active cyanide  present in sar.ples.

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                                 SECTION  IV
                              RECOWENDATIONS

     Several additional avenues of research on measurement  of  cyanide
levels in water samples need to be explored:

     1.   the indication from this work that the acid hydrolysis-
         distillation procedure for total cyanide gives  low cyanide
         results when metal ions are present in solution need; to  be
         confirmed;

     2.   a procedure for concentrating cyanide in natural water
         samples must be developed so accurate determinations  with
         the cyanide electrode can be made;

     3.   determination of the mechanism of decomposition of metal-
         cyanide complexes (if indeed any decomposition  occurs) in
         natural and wastewaters should be investigated.  If it can
         be shown that these complexes are nearly totally stable,  or
         if their decomposition mechanism results in destruction of
         the cyanide (e.g. to methane and ammonia), then it can be
         convincingly argued that free cyanide and NOT total cyanide
         is the only environmentally meaningful measurement.

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                                 SECTION V
                               EXPERIMENTAL
Measurements
     All readings in this report were collected using an Orion Model 801A
DigitalpH/raVolt meter, an Orion Model 90-02 double junction reference
electrode and an Orion Model 94-06 cyanide electrode.

Solutions

     All solutions were prepared from reagent grade potassium cyanid**
Hydroxide concentrations were established using standard solutic .  p-.e-
pared from Acculutes prepared by Anachemia Chemicals Ltd. and obtained
from the Sargeant-Welch Company.  Sodium nitrate was used to adjust the
ionic strength of solutions to 0.10M_ although most readings were carried
out in  0.10M NaOH (pH = 13) solutions.  The outer chamber of the double
junction reference electrode was filled with a 10% solution of sodium
nitrate.

     All other chemicals used were of reagent grade except the potassium
tetracyanonickelate  (II) which was prepared by the procedure given in
Inorganic Synthesis, volume 1.

     Distilled water was used to prepare all solutions.  Checks of the
cyanide level in the distilled water with the cyanide-electrode always
indicated considerably  less than 10~^M_ concentration.

Stock and Standard Solutions

     A  0.10M_ stock solution of potassium cyanide at a pH of 13 was pre-
pared at least once  a month for most of the succeeding readings.  From
this solution were prepared a series of standard solutions ranging  in con-
centration from 1 x  10"3M  (26 ppm) to 1 x  10'7M  (2.6 ppb) cyanide.  These
standard solutions were prepared fresh at  least once every two weeks.
All solutions were stored  in polyethylene bottles.  No sign of decom-
position was observed for  any solution.  A 1 x 10"5M (.26 ppm) cyanide
solution at  a pH of  13  gave the  same  electrode response  even after a four
month storage period.

Operating Procedure

     The instrumental techniques and  general operating procedures used
with the cyanide electrode and  digital pH  meter were those suggested by

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the manufacturers of the equipment.  In general, readings were taken
while stirring and after a wait of one or two minutes for stabilization.
Under certain conditions (e.g. dilute solutions, high pH studies, etc.)
drifting and fluctuating results were observed requiring longer waiting
periods.

     Calibration curves of electrode potentials versus pCN (the negative
logarithm of the cyanide molarity) were prepared on the average of once a
week and were always made immediately prior to taking readings deemed im-
portant.  The curves were always linear and Nernstian over the concen-
tration range of 10"-*  (26 ppm) to  10'^M (.26 ppm) cyanide.  The slopes of
these plots ranged from 56 to 65 although usually they were close to 59,
the theoretical value  for 24°C.  The range of values for the slope are
partially a result of  poor temperature control in the room this work was
carried out in during  the summer months.  The temperature of the samples
in the course of this  study ranged from 23°C to 30°C although for most,
the temperature was 24°C.  No attempt was made to take thermostatted
readings.

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                                 SECTION VI
                                   DATA

     The results of the applicability of the cyanide electrode for
measuring free and total cyanide will be reported in three sections:

     1.  Does the cyanide electrode respond to free cyanide alone?

     2.  Can the cyanide electrode be used to directly determine
         total cyanide content?

     3.  Can the cyanide electrode be used with the hydrolysis-
         distillation procedure to determine total cyanide?

Does the Cyanide Electrode Respond to Free Cyanide Alone?

     The data which follow indicate a definite "yes" as an answer to
this question.  The specifications supplied by the Orion Company with
the cyanide electrode require work at pH values greater than 9.5 where
all cyanide is in an ionic, unprotenated form.  The electrode does not
respond to cyanide when it is in the form of hydrogen cyanide in solu-
tion.  The manufacturer makes no statement about the electrode response
to solutions containing metal-cyanide complexes, however.

     In considering potential metal-cyanide complexes for study, it was
felt important to choose both stable, kineticly labile complexes, and
stable, kineticly inert complexes.  The tetracyanonickelate  (II) complex,
Ni(CN)4^, was chosen as an example of a kinetic labile, thermodyanamically
stable complex for this and subsequent studies.  The ferrocyanide Fe(CN)£4>
and ferricyanide, Fe(CN)^, ions were chosen for their kinetic inertness
a factor that needed careful consideration if the conclusions of this
study were to be applied to complexes generally.  The thermodynamic and
kinetic characteristics of these and other cyanide complexes are given  in
Table 2.   In this table the thermodynamic stability of the metal-cyanide
complexes  can be seen from their very large stability constants.  The
kinetic inertness of the iron-cyanide complexes and the kinetic  lability
of others  is apparent from the  rates of ligand exchange given.

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TABLE 1.  Stability equilibrium constants (Ks) and rates of ligand
           exchange for some typical metal-cyanide complexes

Complex
Ni(CN)42
Mn(CN)63
-4
Fe(CN)6
Fe(CN)63
Hg(CN)42
Ks
io30
io27
37
10
io44
io42
Exchange rate
Very fast
Measurable

Very slow
Very slow
Very fast

-4
TV.» -,AU >roi.3), both uncorrected for sodium error, were chosen for sub-
sequent measurements.  The response of the cyanide electrode to 1.00 x
10"^M_ (2.6 ppm) cyanide at these pH values were  -157.5 millivolt at pH
=  12.7 and -158.4 millivolt at pH = 9.8.  The 9.8 value represents a
near  lower limit for the pH before protonation begins to appreciably re-
duce  the  syanide concentration.  The good agreement of the millivolt
readings  experimentally verifies that essentially all cyanide  is in the
non-protenated  form at these pH values.
      The  effect  of the  response of  the  cyanide  electrode to the addition
 of  various  cyanide-metal  complexes  to a 1.00  x  10"4M  (2.6 ppm) cyanide
 solution  was  investigated.   Specifically, reagent grade ferrocyanide,
 reagent grade ferricyanide  and the  tetracyanonickelate  (II) ion  (prepared
 according to  the procedure  in Inorganic Synthesis) were used.  In Table 2
 are some  typical results.

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TABLE 2.  Response of the cyanidfi electrode to metal-cyanide complexes
           at different pH values
                                p_H _ Relative millivolts*

      pH 9.8

      1.00 x  10~4M KCN                                       -62.2

  100 ml 1 x  10~4M KCN +  .lg KFe(CN)                        -57.2
   100 ml  1 x  10"4M KCN +  .lg K4Ke(CN)6                       -61.8

   100 ml  1 x  10"4M KCN +  .lg K2Ni(CN)4                       -62.0

      pH  12.70

      1.00 x  10"4M KCN                                       -62.0

   100 ml  1 x  10"4M KCN +  .lg K3Fe(CN)6                       -61.1

   100 ml  1 x  10~4M KCN -«•  .lg K4?e(CN)6                       -61.3

   100 ml  1 x  10"4M KCN *  .lg K2Ni(CN)4                       -6?.. 8


 *In  this  table  and most  succeeding  tables  relative  millivolt units  are
  used since  it  is relative changes  that  are  of interest.

                                                      -4
      In all  cases addition of  cyanide complexes to  10 M  (2.6  ppm)  CN"
 solutions result in  an increase in  cyanide potential  implying  a  decrease
 in the  cyanide  concentration as sensed by  the cyanide electrode.  While
 all  decreases are very small and are nearly  within  experimental  error,
 these decreases could be resulting  from  cyanide in  solution complexing
 with uncomplexed metal  impurities in the metal-cyanide complexes used.
 If the  cyanide  added in  the above complexes  were free, a  cyanide molarity
 of about  2.5 x  10~2M (650 ppm) would be  realized.   This  is a 250-fold
 increase  over the  1  x 10"*M_ (2.6 ppm) cyanide present in  the original
 solution.  It thus  appears that the cyanide  electrode does not respond  to
 complexed cyanide,  but  only the free and uncomplexed c>anide.

      The  lack of an  increase in cyanide  in these solutions might be due
 to the  kinetic  inertness of these complexes.  For example, while the
 tetracyanonickelate  is very labile with  an exchange half-life of only 30
 seconds,  the ferrocyanide, with considerable ligand field stabilization
 energy, has  an  exchange  half-life of about 25 days.  To better evaluate
 the  response of the electrode to cyanide complexes without the compli-
 cation  of kinetic effects, additions of aqueous solutions of metal  ions

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into cyanide solutions and the response of the cyanide electrode to
indicate formation of cyanide complexes was observed.   The responses of
the cyanide electrode to additions of 1.0 x 10~3M (about 60 ppm for
first transition series metals) aqueous metal ions to  100 ml of l.uO
x 10"4W[ (2.6 ppm) cyanide were made at two pH values.   The results are
given in Table 3.

TABLE 3.  Relative response in millivolts of the cyanide electrode to
           successive 1 ml additions of 1.0 x lO-^M metal ions to 100.0 ml
           of a 1.0 x 10"^ (2.6 ppra) cyanide solution


1 x 10"4M CN~
(100 ml)
+ 1 ml
metal ion
+2 ml
metal
+ 3 ml
metal
+4 ml
metal
at pH = 9.8
Fe*3
Fe*2
Ni*2
Cu+2
Ba*2
s/2
Zn+2
Pb*2
Mn*2
-63.0
-61.0
-63.0
-61.2
-61.6
-61.8
-62.3
-61.5
-62.6
-60.5
-56.2
-52.3
-53.4
-60.8
-61.0
-58.9
-59.8
-61.2
-54.8
-51.8
-36.5
-45.3
-59.6
-60.4
-55.0
-57.6*
-60.5
-44.4
-46.0
- 5.6
-34.1
-58.8
-59.8
-51.9
-55.0*
	
-28.7
-37.8
—
-18.6
-58.1
-59.4
—
	
	
at pH = 12.70
Fe*3
Fe*2
Ni*2
Cu*2
-61.2
-60.7
-60.5
-61.6
-59.8
-57.2
-56.1
-58.5
-58.3
-56.2
-47.8
-55.7
-57.6
-55.3
-35.5
—
-56.9
—
-19.2
-46.7

 *Precipitate forms
                                    10

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     These data at pH 9.8 show that Ni   and Cu   quite strongly complex
with cyanide removing it from solution as far as the cyanide electrode
response is concerned.  For a 3 x 10~5M Ni*2 concentration (1.76 ppm),
the free cyanide concentration has been reduced from 1.00 x 10"4M (2.6 ppm)
to 1.1 x 10~SM (.29 ppm).  This implies that each Ni*2 has complexed with
3 cyanide ions, or that three out of every four nickel ions exists as a
tetracyano complex.  Again, it is very clear that the cyanide electrode is
NOT responding to complexed cyanide.  Moreover, at a pH of 9.8 it appears
that 1 ppm iron (II), and 2 ppm iron (III) complex with cyanide to a
significant level, while zinc (II) and lead (II) show yet smaller effects.
Barium and strontium ions which could not conceivably complex with cyanide
show the slight positive shift in potential observed earlier for addition
of metal complexes.  This small positive shift is possibly due to ionic
effects or the presence of metal ion impurities.  Dilution cannot account
for the magnitude of decrease observed.

     At a pH of 12.70 the addition of nickel shows a significant reduc-
tion in the free cyanide level.  Copper (II) shows a smaller, but definite
effect, while Fe  (II) and Fe  (III) may exhibit a very small effect.  Only
by working at a pH value of 14 did the nickel-cyanide complex prove un-
staole:
1 x 10"4M CN-
(100 ml)
-143 millivolts
+1 ml 10"3M
• (Ni*2)
-146
+ 2 ml
-144
+ 3 ml
-142
+4 ml
-140
At this pH, however, the data had larger errors because of larger fluctu-
ations in the digital readings.

     These data demonstrate that the cyanide electrode does not respond to
complexed cyanide, but only free cyanide ions.  It must be kept in mind
that the readings must be taken at pH values of about 10 and above and that
caution must be taken in relating a free cyanide reading at a pH of 10 to
that in the sample at pH of 7.  As will be shown later in this report, how-
ever, the free cyanide concentration in natural water samples with its usu-
al range of metal contaminents is probably nearly the same at pH = 10 as
pH = 7.

Can the Cyanide Electrode Be Used to Directly Determine the Total Cyanide
Content?

     In the previous section the cyanide electrode was shown to respond to
free cyanide only.  Since the classical hydrolysis-distillation procedure
for determination of total  cyanide  is a time consuming  (at least one hour
of distillation) one, it was considered profitable to investigate the
possible use of the electrode for determining the total cyanide content of
solutions directly without  prior distillation of hydrogen cyanide from
solution.  To measure total cyanide a complexing agent capable of decom-
posing the metal-cyanide complexes would be necessary.  The two agents

                                     11

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investigated in this study were hydroxide and ethylenediaminetetraacetic
acid (EDTA).  The pH dependence of the formation of the metal-cyanide
complexes is clearly evident in the previous discussion.   The question
here is not one of the formation of the complexes,  but rather, one of
their decomposition.  Their demonstrated thermodynamic instability at
pH = 13 (except nickel) does not necessarily require their kinetic in-
stability.  The stability of the ferrocyanide and ferricyanide as a
function of pH is shown in Table 4.

TABLE 4.  Relative millivolt readings
                                                         After heating
	p_H	Arter mixing    1 day later	1 hour

2 x 10"5M Fe(CN)"3 at:
        —       o

      pH 7                  250             205               210

      pH 10                 156             198               181

      pH 11                 131             139               120

      pH 12                 136             133               106

      pH 13                 134             131               109

2 x 1C"5M Fe(CN)"4 at:
        —       o

      pH 10                 177             ---               118

      pH 12                 206             ---                61

      pH 13                 227             132
      If all of the cyanide had been released to the solution as free
 cyanide a  relative millivolt  reading of  -10 millivolts would have been
 realized.  These  data  demonstrate the tremendous kinetic stability of
 the  iron-cyanide  complexes.   After two days at room temperature and one
 hour under reflux, less  than  1%  of the ferrocyanide-cyanide was re-
 leased and less than 10% of the  ferrocyanide-cyanide.  These results
 imply that distillation  times of 24 hours  or lorger would be required
 to obtain  near quantitative release of cyanide from iron-cyanide com-
 plexes.  A procedure requiring distillation times  of  this magnitude
 obviously  represents no  improvement over the classical acid-hydrolysis-
 distillation  procedure.   Further investigation of  hydroxide-decom-
 position of metal-cyanide was dropped at this point although additional
                                    12

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work ought to be carried out to find conditions or catalyst to facilitate
this decomposition.

     EDTA, an excellent chelating agent for most metals, was next investi-
gated as a potential general agent for decomposing metal-cyanide com-
plexes and freeing all cyanide.  It was anticipated that the EDTA would
complex with metal ions in solution, preventing metal-cyanide complex
formation and thus giving cyanide readings corresponding to the total
cyanide concentration in the solution.  In order to evaluate whether
EDTA formed metal complexes more stable than the metal-cyanide complexes,
addition of 1.0 ml portions of 1.0 x 10-3M (58 ppm) Ni+2 to 100 ml of
1.00 x 10"4M (2.6 ppm) cyanide containing 1.00 ml of 1.10M disodium EDTA
were made at pH = 13.  The results are given in Table 5.

TABLE 5.  Relative response in millivolts of the cyanide electrode to
           the addition of nickel (II) and copper  (II) to solutions con-
           taining both EDTA and cyanide  (pH 13 j

ml 10'3-
Ni*2 added
0.0 ml
1.0
2.0
3.0
4.0
10" MCN-
without
EDTA
-60.5 mVolt
-56.1
-47.8
-35.5
-19.2
10"4MCN-
with
EDTA
-58.0 mVolt
-55.0
-54.0
-52.0
-51.0
ml 10"3M
Cu+2 ~
added
0.0
1.0
2.0
3.0
4.0
10"4M CN-
without
EDTA
-61.6
-58.5
-55.7
	
-46.7
10 M CN~
with
EDTA
-59.0
-56.0
-54.0
-52.0
-51.0

     These  results  show  that  EDTA  appears  to  have  some  effect,  although
 by  no  means complete,  in blocking  the  interferences of  both copper  and
 nickel,  the two  metals found  to  form the cyanide complexes most stable
 in  strongly basic  solutions.   This implies that the metal-EDTA  complexes
 are slightly more  stable than the  metal-cyanide complexes and that  EDTA,
 thus,  might dissociate the  metal-cyanide complexes to allow the cyanide
 electrode to measure  total  cyanide in  solutions.

     Again  the reverse experiment  is the relevent  one.   While the  above
 data demonstrate the  EDTA-metal  complexes  to  be more  stable, the im-
 portant  question is whether EDTA will  kinetically  decompose the metal-
 cyanide  complexes  to  release  complexed cyanide.  To answer this question
 the following experiments were run with ferrocyanide  and tetracyanonic-
 kelate (II):  to 100  ml  of 1.00 x  10"^ (2.6  ppm)  cyanide were  added
 successive 1.00 ml  increments of 1.0 x lO"3^ (about 60  ppm) metal  ions.
 Reduction of the free cyanide concentration was observed as metal-
 cyanide  complexes  formed as reported earlier  in the  first  section.  After
 waiting  until metal-cyanide complex formation was  complete,  1.00 ml of
                                     13

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0.10M disodium EDTA was added and the response of the cyanide electrode
to cyanide as the metal-complexes decomposed was observed.   Data for
nickel are given in Table 6.

TABLE 6.  Relative response in millivolts of the cyanide electrode to
           the dissociation of the nickel-cyanide complex by EDTA at
           pH 13

Solution
100.0 ml 1.00 x 10"4M CN~
+1.00 ml 1.0 x 10"3M Ni*2
+2.00 ml Ni*2
+3.00 ml Ni*2
+4.00 ml Ni*2
+5.00 ml Ni*2
Above solution after 20 minutes
Ab~'ve solution after 1 hour
Above solution after 1 1/2 hours
Solution + 1.00 ml 0.10M EDTA
Above solution after 1/2 hour
Above solution after 21 hours
Above solution after 26 hours
After 47 hours and 1 hour reflux
Relative millivolt reading
0.0
3.6
6.7
10.8
17..,
24.0
29.5
45.2
50.0
47.5
45.0
33.0
33.0
3.3

      Since  the  electrode gives  nearly the  same  response  at  the  end  of
 the  experiment  as at the beginning,  these  data  show that EDTA will  give
 virtually quantitative decomposition of the nickel-cyanide.   Refluxing,
 however,  is necessary to effect this decomposition.   The unexpected
 kinetic stability of the very labile nickel-cyanide complex renders
 EDTA decomposition of inert iron-complexes an unlikely prospect.  A
 similar study to the above, using iron (II) is  place of  nickel  (II)
 seemed to confirm the very slow iron (Il)-cyanide complex decomposition,
                                    14

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but since the iron (II)-cyanide stability is less than that for nickel
the magnitute of the changes were much smaller and thus more difficult
from which to draw conclusions.

     At this point, neither hydroxide nor EDTA have proven to be
effective in quickly decomposing metal-cyanides to enable direct
electrode measurement of total cyanide in solution.  While these ex-
periments demonstrate the electrodes inability to simply measure total
cyanide, they also dramatically show that the free-cyanide response of
the cyanide electrode is to a large degree, pH independent.  If the
free-cyanide level in a natural water sample at a pH of 7 is needed,
adjusting the pH to 10 will have little change in the free-cyanide
level.  The cyanide electrode, thus, represents a means of accurately
assessing the free cyanide concentration in natural water samples.
The high thermodynamic stability of nickel and copper cyanide com-
plexes renders them stable at this pH whereas the kinetic stability of
the iron-cyanide complexes prevents their dissociation in the time re-
quired to make a reading.

Can the Cyanide Electrode Be Used with the Hydrolysis-Distillation
Procedure to Determine Total Cyanide?

     The inability to  find a chemical agent for decomposition of metal-
cyanide complexes  led  to studies of the classical hydrolysis-distilj.a-
tion procedure for total cyanide determination.   It was felt that the
cyanide electrode would at least supply a  faster  and  simpler method for
analysis of cyanide after distillation than the spectrophotometric or
titration procedures usually employed.  Moreover,  the  remarkable
stability of the metal-cyanide complexes observed to  this  point  led to
questions of their stability in  acid  solutions.   Specifically of
interest was the question of whether  these complexes  were  completely
decomposed  in  the  acid-hydrolysis-distillation procedure used  in  cyanide
determinations  (Methods  for Chemical  Analysis of  Water and Wastes,  1971,
Environmental  Protection Agency, pages 41-52).

      The reliability of  the method  was first  checked  using potassium
cyanide  solutions.   In the procedure  used, 50.0 ml  of a cyanide  solution
was  nydrolyzed  and pulled by  aspirator vacuum through a sintered  glass
bubbler into 50.0  mi of a  0.1  M  NaOH  solution.  The cyanide concentrations
of the solutions  before  and after  hydrolysis  thus should be the  same  if
the  apparatus  is  working correctly.   Verification of this  is seen in
Table 7.
                                     15

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TABLE 7.  Response of the cyanide electrode to the cyanide concentrations
           in solutions resulting from acid hydrolysis-distillation of
           solutions of KCN and metal-cyanide complexes
Determination number
Acid hydrolysis-distillation of KCN solutions
          1          2              3
Cyanide millivoltage
 before distillation

Cyanide millivoltage
 after distillation

CN~ cone.
     -253.0
     -250.0

    lxlO"4M
   (2.6 ppm)
 -214.0
 -217.0

3xlO"5M
   -281.0
   -270.0

2.5xlO~4M
                                              (.78 ppm)    (6.5 ppm)
     When solutions of accurately weighed cyanide complexes were treated
by acid hydrolysis to investigate their stability under acidic conditions,
the results were not consistent, however.  Typical results can be seen in
Table 8.

TABLE 8.  Acid hydrolysis-distillation of metal-cyanide complexes

K-Fe(CN), K.Fe(CN),3H 0 K.Ni(CN) .2H .0
OD 462 242
CN- exp.
found
2.51xlO"4M
1.26xlO"4M
0.95xlO"4M
1.55xlO"4M
1.01xlO~4M
CN' exp. CN' exp.
CN~ calc. found CN' calc. found CN" calc.
.99xlO'4M .89X10'4 1.36xl(T4 0.8xlO'4M l-21xlO'4M
1.16xlO"4M --- --- 0.75xlO"4M 1.44xlO"4M
1.46xlO"4M --- --- 0.31xlO~4M 1.44xlO~4M
1.15xlO"4M
1.15xlO"4M

      Generally  the  tetracyanonickelate  complex  gave results consistently
 lower in  cyanide  than  it  should have.   The  ferricyanide results were
 spurious  once giving 2.5  times as much  as experimentally  calculated,  and
 once  only 75%.  The difficulty in making accurate measurements of  this
 type  lies in the  fact  that  a  shift  in pCN from  4.0 to  4.1 means a  change
 from  1.0  x 10'4 to  0.8 x  10'4.  Thus, a 2.5%  error in  the potential
                                     16

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reading in this case is reflected as a 20% error in cyanide concen-
tration.  The daily shift in the working millivolt versus pCN curve is
frequently greater than 2.5% introducing significant errors.  The lack
of consistent air conditioning during the summer months has also in-
troduced errors by greater than desired temperature fluctuations.
Nonetheless, there is some evidence that the presence of nickel will
cause low cyanide results in acid hydrolysis determinations.

     To reduce experimental error and observe the interference of metal
ions in the acid hydrolysis determination of cyanide the following
determinations were made.  The cyanide electrode response to a known
solution containing cyanide was measured, additions of metal ions to
the solution were made, and the solution immediately acid hydrolysed
and distilled to release the cyanide into an identical volume of
0.10M NaOH.  The response of the cyanide electrode to this final
solution was then made.  Since the initial and final solution volumes
are kept the same, and since the readings are made close in time to
each other, the interference of the metal ions should be reflected with
minimum experimental error.  Results of these determinations with 0.1 g
samples of nickel  (II), copper  (II) and iron (II) nitrates added are
shown in Table 9.

TABLE 9.  Effect of metal ion on the recovery of cyanide with acid
           hydrolysis-distillation
     Item	Run  #1	Run  »2	Run *3	Run 04	Run *5

Millivolt  before
  adding metals       -165          -165        -100         -253         -271

Millivolts after
  adding metals  §     -155          -153        - 83         -235         -260
  distilling

CN-  Molarity        IxlO"4       IxlO"4       IxlO*5       IxlO"4      2.5xlO~4
                   (2.6  ppm)    (2.6 ppm)    (.26 ppm)    (2.6 ppm)    (6.5  ppm)
      These data clearly show that metal  ions will  cause low results  in
 the acid hydrolysis-distillation determination of  cyanide.   The results
 nearly always are 40% to 50% low.  Extended distillation times  on several
 samples failed to release significantly  larger cyanide concentrations.

      At this point it appears that metal ions cause low cyanide results
 even when the acid-hyJlrolysis-distillation procedure is used.   While it
 is true that the 250 ppm metal ion concentration used in the last sequence
 of determinations is very high,  the data demonstrate an effect  that  is
 very important and needs further study.   At this point it appears that
 even the classical acid-hydrolysis, distillation procedure does not  always


                                     17

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yield the total cyanide levels in samples with large metal-ion concen-
tration.

     One of the principle purposes of this work was to check the response
of the cyanide electrode with natural water samples as well as laboratory-
prepared samples.  The original intention was to use samples collected by
the Miami Conservancy District and arrangements for this had been made.
Unfortunately, due to cut-backs in financial support, the Miami Conser-
vancy District reduced their sample collection from daily to monthly.
While they would have supplied us with samples, their sampling schedule
did not agree with our needs.  Samples were obtained instead from the
Springfield Water Pollution Control.  They supplied us with three water
samples:  one from the Mad River above Springfield, one from the Mad
River below Springfield, and one from Buck Creek in Springfield.  They
also supplied us with three frozen fish which died in a large fish kill
in the Mad River in Springfield.  An industry using pickling solutions
with high cyanide as well as nickel and copper ion concentrations was  the
principle suspect in the kill.  We were asked to determine cyanide levels
in the  fish using our cyanide electrode.

     While the meaning and significance of the following results of
natural samples  are not always clear, they are presented to initiate  a
realistic evaluation of some of the limitations of the cyanide electrode
in measuring  cyanide concentrations.  Readings were made on water samples
with the cyanide electrode in two ways.  With the first method, the
solution was  adjusted to a pH of 13 and a reading taken immediately  with
the cyanide electrode.  According to the preceding arguments, this read-
ing should give  some measure of the free-cyanide content of the water.
Some evaluation  of the total cyanide was obtained in the second approach
using the hydrolysis-distillation method and subsequent measurement  of
the cyanide concentration in the solution obtained.  In addition, direct
measurements  with EDTA addition were made even though previous  investi-
gations indicate the problems with this approach.  Results for the Buck
Creek water sample and downstream Mad River samples are given in Tables
10, 11, and 12.
                                     18

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TABLE 10.  Response of the cyanide electrode to the cyanide concen-
            tration in several natural samples using various analysis
            methods

Sample
Buck Creek
Downstream Mad River

Direct elect.
determination
4.2xlO"7M
(11 ppb)
5.6xlO"?
(14 ppb)
Cyanide Molarity
Direct det. Hydro 1 . dist.
EDTA addition determination
1.5xlO"6M 1.58xlO"?-
(39 ppb) (4.1 ppb)
l.SxlO"6 6.3xlO~6
(39 ppb) (163 ppb)

TABLE  11.  Electrode response to solutions spiked with additional
            cyanide  (increased by SxlO'^M)

Cyanide Molarity
Sample
Buck Creek
Mad River
Direct
electrode
response
2.2xlO~5M
(.57 ppmj
3.2xlO"5
(.83 ppm)
Direct
electrode
response
with EDTA
2.2xlO"5M
(.57 ppmj
3.2xlO"5
(.83 ppm)
Electrode response to
cyanide solution obtained
after hydrolysis-dis-
tillation
3.2xlO"5M
(.83 ppmT
3.5xlO"5
(.91 ppm)

 TABLE  12.   Analysis  of fish  from fish  kill

Types of fish
CN'M obtained
ppm CN" in fish

Small fish
Large fish
Crayfish
l.lxlO~4M
1.2xlO"5M
7.94xlO"6M
2.4
0.30
0.15
                                    19

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     The upstream Mad River sample gave cyanide concentrations even less
than the figures in Table 10.  Because these readings were well beyond
the region of Nernstian behavior of the electrode and because considerable
drifting occurred before a reading could be taken their validity is very
questionable.  Even the results in the table are at the extreme limit of
application of the cyanide electrode and contain greater errors than
previous readings.  The data do indicate, however, that addition of EDTA
and heating does release additional cyanide.  The result of the hydrol-
ysis-distillation determination of cyanide in Buck Creek is suspicious
since it is less than that found by direct electrode measurement of the
original sample.  Only large errors in these readings can explain this
inconsistency.

     To measure the recovery of cyanide from these natural water samples
the Buck Creek and downstream Mad River samples were spiked with cyanide
to increase the cyanide concentration by SxlO'^M  (1.3 ppm).  The spiked
solutions were then analyzed for cyanide by direct electrode measurement
and by the hydrolysis-distillation procedure, followed by electrode
measurement.  The results are given in Table 11.  In no case was all the
added cyanide recovered, although the hydrolysis-distillation procedure
gave 64% and 70% recovery.  Again, it seems as if the classical cyanide
procedure gives low results when contaminents are present.  The reason
for the low results by direct electrode response can be rationalized as
a result of aqueous metal-ions in the samples complexing with the
cyanide added.  The low results for the hydrolysis-distillation while
not easily explained are consistent with previous determinations made in
this study.  It is very clear from the data for the spiked solutions that
the known addition method of analysis is entirely unapplicable to
cyanide determinations.

     The fact that the direct electrode measurements give lower cyanide
concentrations  is consistent with the earlier argument that these read-
ings are measuring free and not total cyanide.

     In the  final study using the cyanide-electrode the cyanide content
of two fish  and one crayfish which died in a large fish kill in Spring-
field was determined.  Each fish was liquified using a Waring blender.
No attempt was made to measure the cyanide level  in the resulting
solution since  it contained enormous concentrations of organic con-
taminants.   Rather, the solution was subjected to the acid hydrolysis-
distillation procedure and the cyanide concentration of the solution
obtained determined with the cyanide electrode.  The results are given
in Table 12.  The small size of the one fish precluded confirmation of
the high cyanide  concentration.  The cyanide concentrations in the cray-
fish and large  fish and reasonable copper and nickel ion concentrations
in the fish  as  determined by atomic absorption  led the Springfield Water
Pollution Control to doubt a pickling solution  to be the cause of the  fish
kill.
                                     20

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