G- 82
Report on the Status
of
Chemicals in the Special Review Program
and
Registration Standards in the Reregistration Program
December 1989
Office of Pesticide Programs
U.S. Environmental Protection Agency
Washington, D.C. 20460
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REPORT ON THE STATUS
OF
CHEMICALS IN THE SPECIAL REVIEW PROGRAM
AND
REGISTRATION STANDARDS IN THE REREGISTRATION PROGRAM
TABLE OF CONTENTS
Preface i-ii
Special Review Program
Contents
Introduction 1-1 - 1-2
Special Reviews in Process 1-3 - 1-7
Special Reviews Completed 1-8 - 1-21
Final Determinations on 1-22 - 1-26
Pre-Special Reviews
Final Actions - Voluntary Cancellations 1-27 - 1-30
Cancellations Issued Prior to 1-31
RPAP/Special Review Process
Reregistration Program
Introduction 2-1 - 2-2
Registration Standards Issued 2-3 - 2-12
Registration Standards 2-13
Scheduled to be Issued
Index
Prepared by:
Public Information Branch
Field Operations Division
Office of Pesticide Programs
(703) 557-2805
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REPORT ON THE STATUS
OF
CHEMICALS IN THE SPECIAL REVIEW PROGRAM
AND
REGISTRATION STANDARDS IN THE REREGISTRATION PROGRAM
Preface
This report presents an overview of the Special Review
process and the Reregistration process followed by alphabetical
listings of all chemicals which have been or are currently in
Special Review and all chemicals for which Registration Standards
have been issued or are scheduled to be issued. The Special Review
and Reregistration programs are managed by the Special Review and
Reregistration Division, Office of Pesticide Programs.
Copies of Position Documents and Registration Standards are
available to the public through the National Technical Information
Service (NTIS), ATTN: Order Desk, 5285 Port Royal Road,
Springfield, Virginia 22161, (703) 487-4650. When requesting a
document from NTIS, state the name of the document and the NTIS
publication number (PB).
For a complete list of documents available from NTIS with
prices, contact the Document Management Section, Information
Services Branch, Program Management and Support Division (H7502C),
Office of Pesticide Programs, EPA, Washington, D.C. 20460. Draft
Registration Standards are available from the Public Information
Branch, Field Operations Division (H7506C), Office of Pesticide
Programs, EPA, Washington, D.C. 20460.
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SPECIAL REVIEW AND REREGISTRATION DIVISION
OFFICE OF PESTICIDE PROGRAMS
ENVIRONMENTAL PROTECTION AGENCY
Director Edwin Tinsworth
Deputy Director Margaret Stasikowski
Chief, Special Review Branch Janet Auerbach
Chief, Reregistration Branch Lois Rossi
Chief, Generic Chemical Jay Ellenberger
Support Branch
ii
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Status
of
Chemicals in the Special Review Program
December 1989
Office of Pesticide Programs
U.S. Environmental Protection Agency
Washington, D.C. 20460
/
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STATUS
CHEMICALS IN THE SPECIAL REVIEW PROGRAM
Introduction 1-1 - 1-2
Special Reviews in Process 1-3 - 1-7
Alachlor
Aldicarb
Amitrole
Carbofuran
2,4-D [also 2,4-DB and 2,4-DP]
Daminozide
1,3-Dichloropropene
Dichlorvos (DDVP)
EBDCs
Ethylene Oxide
Inorganic Arsenicals (non-wood use)
Pentachlorophenol (non-wood use)
TPTH (Triphenyltin hydroxide)
Tributyltins (antifoulant use)
Special Reviews Completed 1-8 - 1-21
Amitraz
Benomyl
Cadmium
Captafol
Captan
Carbon Tetrachloride
Chlorobenzilate
Coal Tar and Creosote (non-wood use)
Creosote (wood use)
Cyanazine
DBCP (Dibromochloropropane)
Diallate
Diazinon
Dicofol
Dimethoate
Dinocap
Dinoseb
EBDCs
Endrin
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Special Reviews Completed (cont'd)
EPN (Ethyl (p-nitrophenyl)thiobenzene phosphonate)
Ethalfluralin
Ethylene Dibromide (EDB)
Goal (Oxyfluorfen)
Inorganic Arsenicals (wood use)
Lindane
Linuron
PCNB (Pentachloronitrobenzene)
Pentachlorophenol
Pronamide
Sodium Fluoroactetate (Compound 1080)
Strychnine/Strychnine Sulfate
2,4,5-T/Silvex
Th iophanate-Methyl
Toxaphene
2,4,5-Trichlorophenol (TCP)
Trifluralin
Final Determinations on 1-22 - 1-26
Pre-Special Reviews
Cacodylic Acid and Salts
Carbaryl
Chlorinated Isocyanurates
Chloroform
Diflubenzuron (Dimilin)
Fluoroacetamide (Compound 1081)
Maleic Hydrazide
Methanearsonates (includes Amine Methanearsonate,
Calcium Acid Methanearsonate (CAMA), Monodosodium
Methanearsonate (MSMA), Disodium Methanearsonate
(DMSA))
Naled
OBPA (10,10'-0xybisphenoxarsine)
Paraquat Dichloride
Piperonly Butoxide
Rotenone
Terbutryn
Triallate
S,S,S-Tributyl Phosphorotrithioate
Tributyl Phosphorotrithioite
Trichlorfon
Final Actions - Voluntary Cancellations 1-27 - 1-30
Acrylonitrile
Arsenic Trioxide
Benzene
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Final Actions - Voluntary Cancellations (cont'd)
BHC
Captafol
Carbon Tetrachloride
Chloranil
Chlordane
Chlordimeform
Copper Acetoarsenite
Copper Arsenate
Cyhexatin
Endrin
EPN (Ethyl(p-nitrophenyl)thiobenzene phosphonate)
Erbon
Heptachlor
Monocrotophos
Monuron
Nitrofen (TOK)
OMPA (OctamethyIpyrophosphoramide)
Perthane
Phenarsazine Chloride
Ronnel
Safrole
Sodium Arsenite
Strobane
2,4,5-Trichlorophenol
Trysben
Cancellations Issued Prior to 1-31
RPAR/Special Review Process
Aldrin
Chlordane/Heptachlor
Chlordecone (Kepone)
ODD (TDE) (Dichlorodiphenyl dichloroethane)
DDT (Dichlorodiphenyl trichloroethane)
Dieldrin
Mirex
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Special Review Process
On November 27, 1985, the Agency promulgated a final rule
which established new criteria for the initiation of a Special
Review (40 CFR Part 154.7). The Special Review process is set in
motion when the Agency has reason to believe that the use of a
pesticide may result in unreasonable adverse effects. The criteria
for initiating a Special Review of a pesticide use are:
1. Acute toxicity to humans or domestic animals.
2. Potential chronic or delayed toxic effects in humans.
3. Potential hazards to non-target organisms.
4. Risk to the continued existence of any threatened or
endangered species.
5. Risk of destruction or other adverse modification of a
critical habitat of any threatened or endangered species.
6. Any other adverse effect to humans or the environment
which may outweigh the benefits that justify initial or
continued registration.
Registrants receive private notification that the Agency is
considering issuing a Notice of Special Review. This private
notification commences the pre-Special Review phase of the process.
The registrant has 30 days to dispute the validity of the Agency's
concerns.
If, after private notification to the registrants, the Agency
tentatively determines that use of the pesticide does not pose a
significant risk, a Federal Register (FR) notice is issued which
explains the reasons for the Agency's decision. This notice also
announces the availability of the public docket, which includes the
pre-Special Review notification and all written information
received in response to the notification. The FR notice also
solicits public comment, after which the Agency makes a final
decision on whether to initiate a Special Review.
If the Agency determines that a significant risk may be
associated with a pesticide, a Notice of Special Review (Position
Document 1) will be pub-lished in the FR. This notice describes
the Special Review criterion of concern, the assumptions and data
used in the analysis and the strength of the conclusions. The
notice will announce the availa-bility of the pre-Special Review
docket, solicit public comment and request additional information
on the pesticide.
After issuance of the Notice of Special Review, the Agency
may meet with interested parties to discuss the risk concerns and
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available options to reduce the potential risks to health or the
environment. Commencement of the Special Review process is
accompanied by an Agency conducted, comprehensive risk/benefit
analysis of each use of the pesticide subject to Special Review.
Potential risks are evaluated by considering factors such as: 1)
adverse effects to health or the environment; 2) magnitude of
exposure of humans and other non-target organisms; and 3) size of
the population at risk. Benefits of use are evaluated by assessing
the availability, efficacy and cost of alternative control methods,
and impact on users, consumers and other parties (except the
registrant) if the pesticide is cancelled.
A Notice of Preliminary Determination (Position Document
2/3) is then published in the FR for public comment. If the
registrants voluntarily amend their registrations in a manner which
would reduce the risks of the pesticide use to acceptable levels,
the notice explains the Agency's previous risk concerns and the
voluntary resolutions made by the registrants to alleviate the
potential risks. If the registrants do not voluntarily amend the
conditions of registrations in order to reduce risks to an
acceptable level, the notice would include the regulatory measures
the Agency believes are required to reduce risks of the pesticide
use(s) to acceptable levels and a proposed notice of intent to
cancel, deny or reclassify any registrations which do not comply
with these measures.
The Preliminary Determination is then submitted to the
Scientific Advisory Panel (SAP) for comment on the Agency's
scientific rationale. At the same time, the Agency submits the
proposed notice to the United States Department of Agriculture
(USDA) for comment, especially on the benefits issues and
agricultural impacts.
After evaluating all comments received from the USDA, the
SAP, and the public on the proposed action, the Agency will modify
the proposal where appropriate prior to issuance as a final action.
A Notice of Final Determination (Position Document 4) is published
in the FR, along with a Notice of Intent to Cancel, Deny, or
Reclassify Registration if required to implement the determination.
Any such notice becomes effective by operation of law unless the
registrant makes the necessary corrections or a hearing is timely
requested by a person adversely affected by the notice.
The five subsequent sections identify in alphabetical
order: 1) the chemicals which are currently in Special Review;
2) the chemicals which have Special Review final determinations;
3) the chemicals which were returned to the registration process
after a pre-Special Review determination; 4) the chemicals which
were voluntarily cancelled as a result of the Special Review
process; and 5) the chemicals which were cancelled prior to the
RPAR and Special Review processes.
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SPECIAL REVIEWS IN PROCESS
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT STATUS
ALACRLOR
o Oncogenicity
ALDICARB
o Acute Toxicity
o Ground Water
Contamination
AMITROLE
o Oncogenicity
CARBOFURAN
o Wildlife Effects
o PD 1 published 50 FR 1115 on 1/9/85;
comment period closed 4/9/85: NTIS#PB85-
175503. Press release published on 1/3/85.
o PD 2/3 published 51 FR 36166 on 10/8/86;
comment period closed 12/8/86: NTIS# PB87-
181319.
o PD 4 on dietary and applicator risks
published 52 FR 49480 on 12/31/87
required restricted use, label warning,
closed systems for large-scale
mixer/loaders. NTIS # not available.
o PD4 for ground water deferred until 1991.
o PD 1 published 49 FR 28320 7/11/84;
comment period closed 9/11/84.
(NTIS # not available).
o PD 2/3 published 53 FR 24630 on 6/29/88;
comment period closed 9/29/88: NTIS#
PB88-236856.
o PD 2/3 to be reproposed in FY '90.
o PD 1 published 49 FR 20546 on 6/15/84;
comment period closed 7/11/84: NTIS#
PB87-187175.
o A proposed decision scheduled in FY '90.
o PD 1 published 50 FR 41938 on 10/16/85;
comment period closed 12/2/85: NTIS#
PB87-186771.
o PD 2/3 published 54 FR 3744 on 1/25/89;
comment period closed 3/27/89.
o PD 4 to be issued 4/90.
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SPECIAL REVIEWS IN PROCESS
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT STATUS
2,4-D [also 2,4-DB and 2,4-DP]
o Carcinogenicity
DAMIKOZIDE
o Oncogenicity
1,3-DICHLOROPROPENE
o Oncogenicity
DICHLORVOS (DDVP)
o Oncogenicity
o Proposed decision not to initiate Special
Review published 53 FR 9590 published on
3/23/88.
o Final decision to be issued in late FY '90
upon completion and review of two epidemi-
ologic studies.
o PD 1 published 49 FR 29136 on 7/18/84;
comment period closed 8/31/84. (NTIS #
not available).
o Draft PD 2/3/4 issued on 9/12/85.
o Data call-in issued on 2/10/86.
o PD 2/3 preliminary determination to cancel
all food uses published 54 FR 22558 on
5/24/89.
o On June 2, 1989 the registrant voluntarily
halted the sale of daminozide products
registered for food uses, and announced an
immediate recall of these daminozide
stocks.
o Proposed tolerance revocations published
54 FR 37277 on 9/7/89.
o Final Agency decision to be issued in
early 1990.
o PD 1 published 51 FR 36161 on 10/8/86;
comment period closed 12/8/86. (NTIS #
not available).
o PD 2/3 to be issued in FY '90.
o Decision Document published 47 FR 45075 on
10/13/82: NTIS# PB87-181335. The Agency
will reassess carcinogenic potential when
additional Oncogenicity data are received.
o PD 1 published 53 FR 5542 on 2/24/88.
(NTIS # not available).
o PD 2/3 to be issued in FY '90.
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SPECIAL REVIEWS IN PROCESS
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT STATUS
EBDCs (Ethylenebisdithiocarbamates: Maneb, Mancozeb, Metiram,
Nabam, Zineb)
o Oncogenicity
o Teratogenicity
o PD 1 published 52 FR 27172 on Thyroid
Effects on 7/17/87; comment period closed
9/30/87: NTIS # PB87-117990.
o The sole Nabam registrant requested volun-
tary cancellation of all food uses in
3/89.
o Registrants announced on 9/6/89 that they
will drop all but 13 registered food uses.
o On 12/4/89, EPA announced PD 2/3, the pre-
liminary determination to cancel all uses
of Zineb and 45 food crop uses of
Mancozeb, Maneb, and Metiram. 10 crop uses
would be retained. PD 2/3 will be
published in the Federal Register.
ETHYLENE OXIDE
o Oncogenicity
o Mutagenicity
o Testicular Effects
o PD 1 published 43 FR 3801 on 1/27/78;
comment period closed 5/15/78:
NTIS# PB80-213903.
o Petition to revoke Section 409 on spice
uses received 12/16/87 (52 FR 47753).
Response to petition to be issued in
FY 90.
INORGANIC ARSENICALS (non-WOOd use)
o Oncogenicity
o Mutagenicity
o Teratogenicity
o PD 1 published 43 FR 42867 on 10/18/78;
comment period closed 2/12/79:
NTIS# PB87-181327.
o PD 2/3 (which excludes the four uses
listed below) published 52 FR 132 on
1/2/87; comment period closed 2/17/87.
(NTIS f not available).
o PD 2/3 (which will address: turf
herbicide use of calcium arsenate;
grapefruit growth regulator use of lead
arsenate; grape fungicidal use of sodium
arsenite; and desiccant use of arsenic
acid) to be issued in FY '90.
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SPECIAL REVIEWS IK PROCESS
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED CURRENT STATUS
INORGANIC ARSENICALS (non-wood use) (cont'd)
o Registrant of lead arsenate voluntarily
cancelled 9/87 with provisions to sell
existing stocks.
o PD 4 (excluding four uses listed above)
published 53 FR 24787 on 6/30/88. (NTIS #
not available). Registrants of ant bait
formulations filed hearing request on
7/29/88.
o Registrant of calcium arsenate voluntarily
cancelled 2/14/89. Existing stocks
provision to registrant granted until
3/90, all others until 12/31/91.
o Use of sodium arsenate as ant bait
cancelled on 7/26/89 upon completion of
hearing.
PENTACHLOROPHENOL (non-wood use)
o Oncogenicity o PD 1 published 43 FR 48443 on 10/18/78:
o Fetotoxicity NTIS# PB87-109464.
o Teratogenicity o PD 2/3 published 49 FR 48367 on 12/12/84;
comment period closed 2/14/86: NTIS#
PB87-119095. Special Review on oil well,
cooling tower, and pulp and paper uses
deferred until exposure data are received.
PD 2/3 due in 1990.
o PD 4 published 52 FR 2282 on
1/21/87: NTISf PB87-204707. Non-deferred
uses cancelled.
o Amendment to PD 4 (clarifying uses)
published 53 FR 5524 on 2/24/88.
TPTH (TRIPHENYLTIN HYDROXIDE)
o Teratogenicity o PD 1 published 50 FR 1107 on 1/9/85;
comment period closed 2/22/85: NTIS#
PB85-175487.
o Data call-in for additional data issued
5/88.
o PD 2/3 to be issued in FY «90.
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SPECIAL REVIEWS IN PROCESS
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT STATUS
TRIBUTYLTINS (antifoulant use)
o Acute and Chronic
Toxicity to Non-
Target Organisms
o PD 1 published 51 FR 778 on 1/8/86;
comment period closed 2/24/86:
NTIS# PB87-186763.
o PD 2/3 published 52 FR 37510 on 10/7/87:
NTIS# PB88-161203.
o PD 4 published 53 FR 39022 on 10/4/88.
(NTIS # not available). Partial conclusion
of Special Review; requires compliance
with OAPCA release rates and prohibitions,
modified labeling, and restricted use
classification. Final determination
regarding the release of organotin is
pending results of major environmental
monitoring study.
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SPECIAL REVIEWS COMPLETED
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
FINAL DETERMINATION
AMITRAZ
o Oncogenicity
BENOMYL
o Reduction in
Non-target
Organisms
o Mutagenicity
o Teratogenicity
o Reproductive
Effects
o Hazard to Wildlife
CADMIUM
o Oncogenicity
o Mutagenicity
o Teratogenicity
o Fetotoxicity
o PD 1 published 42 FR 18299 on
4/6/77; comment period closed 7/18/77:
NTIS# PB80-212046.
o PD 2/3 published 44 FR 2678 on 1/12/79;
comment period closed 2/12/79: NTIS#
PB80-211436.
o PD 4 published 44 FR 32736 on 6/7/79, 44
FR 59938 on 10/7/79 (correction): NTIS#
PB80-211428.
Conditional registration approved for
pears but not for apples.
o Tolerance for pears approved 12/6/79.
o PD 1 published 42 FR 61788 on 12/6/77;
comment period closed 1/23/78:
NTIS# PB80-216856.
o PD 2/3 published 44 FR 51166 ON 8/30/79;
comment period closed 9/28/79: NTIS#
PB-87-119087.
o PD 4 published 47 FR 46747 on 10/20/82:
NTIS# PB83-148189. Requires use of either
cloth or commercially available disposable
dust masks by mixer/loaders of benomyl
intended for aerial application and that
registrants of benomyl products conduct
field monitoring studies to identify
residues that may enter aquatic sites
after use on rice.
o Registrant completed field monitoring
study and submitted to Agency 11/84.
Study not accepted. New study required by
Registration Standard issued 6/87.
o PD 1 published 42 FR 56574 on 10/26/77;
comment period closed 2/10/78:
NTIS# PB87-181376.
o PD 2/3 published 51 FR 36524 on 10/10/86;
comment period closed 11/24/86: NTISfl
PB87-175782.
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SPECIAL REVIEWS COMPLETED
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
FINAL DETERMINATION
CADMIUM (cont'd)
CAPTAFOL
o Oncogenicity
o Acute and Chronic
o Wildlife Effects
CAPTAN
o Oncogenicity
o PD 4 published 52 FR 31076 on 8/19/87:
NTIS# PB87-228490. Golf course fairway
and home lawn uses cancelled. Golf course
green and tee area uses modified.
o PD 1 published 50 FR 1103 on 12/9/84;
comment period closed 1/31/85:
NTIStf PB85-175495. Press release
published on 1/3/85.
o All registrations voluntarily cancelled as
of 5/15/87.
o Proposed decision to terminate Special
Review published 52 FR 27576 on 7/22/87.
o Final decision published 53 FR 33535 on
8/31/88.
o PD 1 published 45 FR 54938 on 8/18/80;
comment period closed 12/1/80: NTIS#
PB81-109449.
o PD 2/3 published 50 FR 25885 on 6/21/85;
comment period closed 8/5/85: NTIS#
PB87-118011.
o PD 4 published 54 FR 8116 on 2/24/89.
(NTIS # not available).
Certain food use registrations cancelled.
CARBON TETRACHLORIDE
o Oncogenicity
o Toxic Effect
on Liver
and Kidneys
o PD 1 published 45 FR 68534 on 10/15/80;
comment period closed 11/24/80:
NTIS# PB81-121782.
o Voluntary cancellation of many products
published 50 FR 42997 on 10/23/85.
o Cancellation of remaining products
published 54 FR 41004 on 11/12/86.
o Proposed exemption revocation published 52
FR 38200 on 10/14/87.
o Expiration date of 7/31/90 for the
tolerance exemption on grains published 54
FR 6126 on 2/8/89.
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SPECIAL REVIEWS COMPLETED
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
FINAL DETERMINATION
CHLOROBENZILATE
o Oncogenicity
o Testicular Effects
o PD 1 published 41 FR 21517 on
5/26/76; comment period closed
(NTIS # not available).
o PD 2/3 published 43 FR 29824 on
comment period closed 8/10/78:
PB80-213887.
o PD 4 published 44 FR 9547 on 2/13/79:
NTISfl PB80-213929. All uses except citrus
cancelled.
7/28/76.
7/11/78;
NTIS#
COAL TAR AND CREOSOTE (non-WOOd use)
o Oncogenicity
o Mutagenicity
CREOSOTE (wood use)
o Oncogenicity
o Mutagenicity
o PD 1 published 43 FR 48154 on 10/18/78;
comment period closed 12/4/78: NTIS#
PB80-213879.
o PD 2/3 published 49 FR 33328 on 8/22/84;
comment period closed 10/20/84: NTIStf
PB87-178851.
o PD 4 published 50 FR 41943 on 10/16/85:
NTIS# PB87-180485. Cancellation of all
uses except gypsy moth egg masses;
deferral on coal tar neutral oil (CTNO)
use pending receipt of additional data.
o Cancellation of all remaining uses
published 5/15/86.
o PD 1 published 43 FR 48154 on
10/18/78; comment period closed 2/12/79:
NTIS# PB80-213879.
o PD 2/3 published 46 FR 13020 on 2/19/81;
comment period closed 5/20/81: NTIS#
PB82-229956.
o At 4/14/83 public meeting, proposed
conclu-sion presented; comment period
closed 5/13/83.
o PD 4 published 49 FR 28666 on 7/13/84:
NTIS# PB84-241538. Requires label changes
including a restricted use classification.
o Subsequently, two FR notices published:
49 FR 43772 on 10/31/84, and 50 FR 4269 on
1/30/85.
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SPECIAL REVIEWS COMPLETED
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
FINAL DETERMINATION
CYAKAZINE
o Teratogenicity
o PD 1 published 50 FR 6560 on 4/10/85;
comment period closed 5/27/85: NTIS#
PB87-117982.
o PD 2/3 published 52 FR 589 on 1/17/87;
comment period closed 3/9/87: NTISf PB87-
181400.
o PD 4 published 53 FR 795 on 1/13/88.
Requires label warning and
protective clothing. (NTIS # not
available).
o Hearing requested 2/88. Settlement
reached 5/88 revising hazard warning
statement and extending existing stocks
provision.
DBCP (DIBROMOCHLOROPROPANE)
o Oncogenicity
o Reproductive
Effects
o Mutagenicity
o Ground Water
Contamination
o PD 1 published 42 FR 48026 on 9/22/77;
comment period closed 11/7/77: NTIS #
PB87-181368.
o Suspension order and notice of
intent to cancel all food uses published
42 FR 57543 on 11/3/77.
o Amended notice of intent to cancel and PD
2/3/4 published 43 FR 40911 on 9/13/78:
NTIS# PB80-213853.
o Notice of intent to suspend all products
published 44 FR 43335 on 7/24/79.
o Suspension order for all uses except
pineapples published 44 FR 65161 on
10/29/79.
o Notice of intent to cancel all uses
published 44 FR 65170 on 11/9/79.
o Withdrawal of the notice of intent to
cancel use on pineapples published 46 FR
19592 on 3/31/82.
o Proposed intent to cancel use on
pineapples published 49 FR 1556 on
1/12/84; comment period closed 3/12/84..
o Press release published on 1/3/85.
o Final PD 4 published 50 FR 1122 on 1/9/85.
Cancellation of remaining registrations.
(NTIS # not available).
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SPECIAL REVIEWS COMPLETED
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
FINAL DETERMINATION
DIALLATE
o Oncogenicity
o Mutagenicity
DIAZINON
o Avian Hazard
o PD 1 published 42 FR 27669 on
5/31/77; comment period closed 9/9/77:
NTIS# PB80-212863.
o PD 2/3 published 45 FR 38437 on 6/9/80;
comment period closed 7/9/80: NTIS# PB80-
216849.
o PD 4 published 47 FR 27109 on 6/23/82:
NTIS# PB87-118006. Restricted use to
certified applicators wearing protective
clothing.
o PD 1/2/3 published 51 FR 1842 on 1/15/86;
comment period closed 3/3/86; extended to
3/28/86 (5.1 FR 8813): NTIS# PB87-101853.
o PD 4 published 51 FR 35034 on 10/1/86.
(NTIS # not available). Cancellation of
golf course and sod farm uses.
o Amendment to PD 4 published 52 FR 5656 on
2/25/87.
o Registrant-requested hearing confirmed PD
4 decision in 4/88.
o Registrants appealed; PD 4 remanded
pending decision by Administrator.
DICOFOL
o Ecological Effects o PD 1 published 49 FR 10569 on 3/21/84;
comment period closed 5/5/84: NTIS# PB84-
160084.
o PD 2/3 published 49 FR 39820 on 10/10/84;
comment period closed 11/26/84: NTIS#
PB85-134153.
o Amendment to PD 2/3 published 50 FR 33008
on 8/15/85.
o PD 4 published 51 FR 19508 on 5/29/86.
(NTIS # not available). Requires a
reduction in the level of DDTr
contamination, and modified labeling.
1-12
,0
-------
SPECIAL REVIEWS COMPLETED
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
FINAL DETERMINATION
DIMETHOATE
o Oncogenicity
o Mutagenicity
o Fetotoxicity
o Reproductive
Effects
DINOCAP
o Teratogenicity
DINOSEB
o Teratogenicity
o Reproductive
Effects
o Acute Effects
o PD 1 published 42 FR 45806 on
9/12/77; comment period closed
1/6/78: NTIS# PB87-181343.
o PD 2/3 published 44 FR 66558 on 11/19/79;
comment period closed 12/19/79: NTIS#
PB80-213846.
o PD 4 published 46 FR 5364 on 1/19/81:
NTIS# PB81-172413. Denies applications for
dust formulations, and requires modified
labeling.
o PD 1 published 50 FR 1119 on 1/9/85;
comment period closed 2/22/85. (NTIS # not
available).
o PD 2/3 published 51 FR 39577 on 10/29/86;
comment period closed 12/29/86: NTIS#
PB87-178844.
o PD 4 published 54 FR 5908 on 2/6/89.
Requires health hazard label statement and
additional protective clothing.
o Emergency Suspension Order/Notice
of Intent to Cancel published 51 FR
36634 on 10/14/86: NTIS# PB87-
225041.
o As a result of a Subpart D hearing, the
Agency modified the 10/7/86 Suspension
Order to permit use of dinoseb on dry
peas, lentils, and chick peas in Idaho and
Washington during the 1987 growing season.
A District Court order in Oregon permitted
use on green peas and snap beans in 1987
and 1988. Under a settlement agreement
reached between EPA and the registrant in
5/88, use was allowed on cranberries in
1989.
1-13
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SPECIAL REVIEWS COMPLETED
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
FINAL DETERMINATION
EBDCs (Ethylene bisdithiocarbamates: Maneb, Mancozeb, Metiram,
Nabam, Zineb, Amobam)
o Oncogenicity
ENDRIN
o Oncogenicity
o Teratogenicity
o Reduction in
Endangered and
Non-Target
Species
o PD 1 published 42 FR 40618 on 8/10/77;
comment period closed 12/23/77:
(NTIS # not available).
o Decision Document and Final Determination
published 47 FR 47669 on 10/27/82: NTIS#
PB87-181350. Requires modified labeling
and additional toxicological data.
o PD 1 published 41 FR 31316 on 7/27/76;
comment period closed 11/4/76:
NTIS# PB81-112690.
o PD 2/3 published 43 FR 51132 on 11/2/78;
comment period closed 12/4/78: NTIS#PB
119921.
o PD 4 published (including cancellations)
44 FR 43631 on 7/25/79: NTIS# PB81-
109480.
o PD 4 follow-up notice sent 8/28/80.
o Cancellations by Velsicol of one technical
and 2 end-use products effective 11/23/84.
o Velsicol's last end-use product was
voluntarily cancelled as of 8/1/85.
o All but one remaining uses were
voluntarily cancelled effective 9/12/85.
EPN (Ethyl (p-nitrophenyl)thiobenzene phosphonate)
o Neurotoxicity
o Hazard to Aquatic
Organisms
o PD 1 published 44 FR 54384 on 9/19/79;
comment period closed 12/29/79:
NTIS#PB80-216815.
o Determination to conclude RPAR published
in 48 FR 39494 on 8/31/83. Mosquito
larvicide use cancelled. New label
requirements imposed for all other uses to
reduce exposure to applicators and non-
target organisms, and reassess tolerances,
chronic toxicity and reentry.
o Proposed Decision Not To Initiate Special
Review published 52 FR 27453 on 7/21/87.
o Final Decision Not to Initiate Special
Review published 53 FR 48574 on 12/23/87.
o All registrations voluntarily cancelled as
of 7/24/87.
1-14
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SPECIAL REVIEWS COMPLETED
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
FINAL DETERMINATION
ETHALFLURALIN
o Oncogenicity
o PDs 1, 2/3, and 4 published 49 FR 511 on
1/4/84; comment period closed 12/1/85.
(NTIS # not available). Benefits of
conditional registration exceeded risks.
Submission of additional data required by
12/1/85.
ETHYLENE DIBROMIDE (EDB)
o Oncogenicity
o Mutagenicity
o Reproductive
Effects
o PD 1 published 42 FR 63134 on 12/14/77;
comment period closed 4/3/78:
NTIS# PB80-109456.
o PD 2/3 published 45 FR 81586 on 12/10/81;
comment period closed 3/9/82: NTIS# PB81-
157851.
o PD 4 published 48 FR 45956 on 10/7/83:
NTISI PB85-238004.
o Emergency Suspension published 49 FR 4452
on 2/6/84: NTIS# PB85-235919. Uses to
fumigate grain and grain milling equipment
were suspended.
o Proposed tolerances for EDB in grains
published 49 FR 6697 on 2/22/84.
o Proposed tolerances for EDB in citrus and
papayas published 49 FR 8407 on 3/6/84.
o Amendment to Notice of Intent to Cancel
registrations of pesticide products
containing EDB published 49 FR 14182 on
4/10/84.
o Final tolerances for EDB in grains
published 49 FR 17144 on 4/23/84.
o Final revocation of tolerances and
establishment of interim tolerances for
EDB in citrus and papaya published 49 FR
22082 on 5/25/84.
o Proposed revocation of tolerances for
miscellaneous commodities published 49 FR
32085 on 8/10/84.
o Interim tolerance for EDB in mangoes was
published 9/29/86. Tolerance expired
9/30/87.
o Papaya registration voluntarily cancelled
as of 3/87.
1-15
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SPECIAL REVIEWS COMPLETED
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
FINAL DETERMINATION
EDB (COnt'd)
GOAL (OXYFLDORFEN)
o Oncogenicity
o only remaining uses are citrus for export
(use terminated at end of 1988/1989
harvest season), vault fumigation, and
quarantine fumigation of nursery stock.
o PD 1/2/3 published 46 FR 23490 on 4/27/81;
comment period closed 5/11/81: NTIS#
PB82-185133.
o PD 4 published 47 FR 27118 on 6/23/82:
NTIS# PB82-172289.
o Decision made to continue use of the
herbicide subject to certain restrictions
(on PCE) pertaining to formulation of
product.
INORGANIC ARSENICAL8 (wood use)
o Oncogenicity
o Mutagenicity
o Teratogenicity
LINDANE
o Oncogenicity
o Teratogenicity
o Reproductive
Effects
o Other Chronic
Effects
o Acute Toxicity
o PD 1 published 43 FR 48267 on
10/18/78; comment period closed
2/12/79. (NTIS # not available).
o PD 2/3 published 46 FR 13020 on 2/19/81;
comment period closed 5/20/81: NTIS#
PB82-229956.
o At 4/14/83 public meeting proposed
conclusion presented; comment period
closed 5/15/83.
o PD 4 published 49 FR 28666 on 7/13/84:
NTIS# PB84-241538. Requires label changes
including a restricted use classification.
o Subsequently, two FR notices were
published: 49 FR 43772 on 10/31/84, and
50 FR 4269 on 1/30/85.
o PD 1 published 42 FR 9816 on 2/18/77;
comment period closed on 6/20/77:
NTIS#PB80-213861.
o PD 2/3 published 45 FR 45362 on 7/3/80;
comment period closed 9/15/80:
NTIS # PB87-165080.
1-16
-------
SPECIAL REVIEWS COMPLETED
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
FINAL DETERMINATION
LINDANE (cont'd)
o PD 4 published 48 FR 48512 on 10/19/83:
NTIS# PB87-165098. The decision cancelled
the indoor use of smoke fumigation devices
and the use of dog dips to treat pests
other than mites. All other uses will
continue with use restrictions and label
modifications.
o Negotiated settlement on dog dips
published 49 FR 26282 on 6/27/84. A
settlement on smoke bombs published 50 FR
5425 on 2/8/85 to end sale of product by
5/31/86 for registrant and by 11/30/86 for
retailer.
LINDRON
o Oncogenicity
(rebutted)
o PD 1 published 49 FR 37843 on 9/26/84;
comment period closed 11/10/84: NTIS#
PB85-174654.
o Preliminary Decision to Conclude Special
Review published 53 FR 31262 on 8/17/88.
o Final Determination to Conclude published
54 FR 4072 on 1/27/89.
No regulatory action warranted.
PCNB (PENTACHLORONITROBENZENE)
o Oncogenicity
PENTACHLOROPHENOL
o Oncogenicity
o Fetotoxicity
o Teratogenicity
o PD 1 published 42 FR 61894 on
10/13/77; comment period closed
2/6/78: NTISf PB80-216799.
o Special Review was terminated through
negotiated agreement with registrants to
reduce levels of the HCB contaminant and
to make label changes to reduce exposure.
Published 47 FR 18177 on 4/19/82.
o PD 1 published 43 FR 48443 on
10/18/78; comment period closed
2/12/79: NTIS# PB81-109464.
o PD 2/3 published 46 FR 13020 on 2/19/81;
comment period closed 5/20/81: NTIS#
PB82-229956.
o At 4/14/83 public meeting proposed
conclusion presented; comment period
closed 5/13/83.
1-17
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SPECIAL REVIEWS COMPLETED
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
FINAL DETERMINATION
PENTACHLOROPHENOL (COnt'd)
PRONAMIDE
o Oncogenicity
o PD 4 published 49 FR 28666 on 7/13/84:
NTIS# PB84-241538. Requires label changes
including a restricted use classification.
o Subsequently, two FR notices were
published: 49 FR 43772 on 10/31/84 and 50
FR 4269 on 1/30/85.
o Amendment to PD 4 published 51 FR1334 on
1/10/86.
o Amendment to amended PD 4 published
52 FR 140 on 1/2/87.
o Comprehensive DCI issued 8/4/89.
o PD 1 published 42 FR 32302 on 5/20/77;
comment period closed 8/29/77: NTIS#
PB81-109472.
o PD 2/3 published 44 FR 3083 on 1/15/79;
comment period closed 2/14/79: NTIS#
PB80-213911.
o PD 4 published 44 FR 61640 on 10/26/79:
NTIS# PB81-112716. The following actions
were taken: Cancellation of registration
of products allowing hand spray applica-
tions, except for use on ornamentals and
nursery stock; cancellation of registra-
tions of products unless the registrant
modifies the terms and conditions to allow
certain uses of wettable powder products
only by or under direct supervision of
certified applicators; modification of
labeling of wettable powder products to
include specific general precautions,
directions as to protective clothing to be
worn, dilution instructions for wettable
powder products, and watering instructions
for granular products used on turf; and
Agency revision of the lettuce tolerance
from 2 ppm to 1 ppm from required residue
data that was submitted.
1-18
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SPECIAL REVIEWS COMPLETED
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
FINAL DETERMINATION
SODIUM FLUOROACETATE (1080)
o Reduction in Non-
Target and
Endangered
Species
o PD 1 published 41 FR 52792 on
12/1/76; comment period closed
o No Antidote3/15/77: NTIS# PB80-216823.
o PD 2/3 signed on 11/11/82; re-signed on
6/29/83; published 48 FR 50935 on 11/4/83:
NTIS# PB87-182226. Issuance of Pp delayed
to coincide with document addressing
predator issues.
o SAP reviewed PD 2/3 and issued a
final report on 7/3/84, following 6/12/84
SAP meeting.
o PD 4 published 50 FR 31012 on 7/31/85:
NTISfl PB87-116471. Modified labeling and
certain bait concentration reductions
required.
STRYCHNINE/STRYCHNINE SULFATE
o Reduction in
Non-target and
Endangered
Species
o PD 1 published 42 FR 2713 on
1/13/77; comment period closed 3/15/77:
NTIS# PB80-216807.
o PD 2/3 published 45 FR 73602 on 11/5/80;
comment period closed 9/30/81: NTIS#
PB81-123960.
o PD 4 published 48 FR 48522 on 10/19/83:
NTIS# PB87-182234. Decision cancelled use
of strychnine for control of prairie dogs
and several other rodents and small
mammals. All other uses will require
label modifications.
o Notice published 53 FR 6762 on 3/4/87
withdrawing partial cancellation of
strychnine active ingredient pesticides
for prairie dog, ground squirrel, and
meadow mouse control if certain
modifications of terms and conditions of
registration are made. Terms and
conditions include: establishment of a
State program for exclusive distribution
and moni- toring of strychnine for use on
prairie dogs; compliance with Black-Footed
Ferret Survey Guidelines; and use of
certain label statements.
1-19
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SPECIAL REVIEWS COMPLETED
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
FINAL DETERMINATION
2,4,5-T/SILVEX
o Oncogenicity
o Teratogenicity
o Fetotoxicity
THIOPHANATE-METHYL
o Mutagenicity
o Oncogenicity
o Reduction in
Non-target
Species
(Rebutted)
TOXAPHENE
o Oncogenicity
o Population
Reduction in
Non-Target
Animal Species
o Acute Toxicity to
Aquatic Organisms
o Chronic Effects to
Wildlife
o 2,4,5-T PD 1 published 43 FR 17116
on 4/21/78; comment period closed
6/5/78: NTIS# PB80-212665.
o 2,4,5-T: PD 2/3 published 44 FR 41536 on
7/17/79; comment period closed 8/16/79:
NTIS# PB87-117685.
o Silvex: PD 1/2/3 published 44 FR 41536
on 7/17/79; comment period closed
8/16/79: NTIS# PB80-213895.
o Emergency Suspension Order and Notice of
Intent to Cancel published 44 FR 15874 on
3/15/79. 2,4,5-T: NTIS# PB80-225923;
Silvex: PB80-226376.
o 2,4,5-T/Silvex—PD 4 published 44 FR
72316 on 12/13/79: NTIS# PB87-181384.
o Cancellation hearings began 3/14/80.
o On 10/11/84, the Administrative Law
Judge gave Union Carbide 30 days to
determine if they wanted to defend 2,4,5-
T/Silvex uses. Union Carbide and
remaining companies withdrew from the
hearing and all registrations were
cancelled on 1/2/85.
o PD 1 published 42 FR 61970 on
12/7/77; comment period closed
3/27/78: NTIS# PB80-216856.
o PD 2/3 published 44 FR 58798 on 10/11/79;
comment period closed 11/12/79:
NTIS# PB87-119087.
o PD 4 published 47 FR 46747 on 10/20/82:
NTIS# PB83-148189.
warranted.
No regulatory action
o PD 1 published 42 FR 26860 on 5/27/77;
comment period closed 6/13/77:
5/27/77; comment period closed
NTIS# PB80-216732.
o PD 2/3/4 published 47 FR 53784 on
11/29/82: NTISf PB83-144204.
Cancellation of registrations for most
uses and continued registration of
certain uses under specific terms and
1-20
-------
SPECIAL REVIEWS COMPLETED
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
FINAL DETERMINATION
TOXAPHENE (cont'd)
conditions. The continued uses are:
corn, cotton, and small grain for specific
insect infestation (emergency use only);
pineapples and bananas for specific
insects in Puerto Rico and the Virgin
Islands only; and scabies treatments of
cattle and sheep.
2,4,5-TRICHLOROPHENOL (TCP)
o Oncogenicity
o Fetotoxicity
TRIFLURALIN
o Oncogenicity
o Mutagenicity
o PD 1 published 43 FR 34026 on
8/2/78; comment period closed 11/17/78:
NTIS# PB81-103111.
o Action temporarily deferred
pending 2,3,5-T/Silvex proceedings.
o 3(c)(2)(B) letter issued on May 7, 1985
requesting updated Confidential Statement
of Formula, analysis for dioxin
contamination, and teratology data. Most
products were voluntarily cancelled in
response.
o PD 2/3/4 published 52 FR 15549 on 4/29/87:
NTIS# PB87-203113. Cancellation of all
uses.
PD 1/2/3 published 44 FR 50911 on
8/30/79; comment period closed 11/13/79:
NTIS# PB80-213937.
PD 4 published 47 FR 33777 on 8/4/82:
NTIS# PB82-263252. Registration allowed
to continue if total N-nitrosamine
contamination is kept below 0.5 ppm for
technical products, and below a figure
based on trifluralin content for
formulated products.
1-21
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FINAL DETERMINATION ON PRE-8PECIAL REVIEWS
(Returned to the Registration Process)
40 CFR 154.7
CRITERIA OF CONCERN
DATE OF FR NOTICE
AND NTI8 PUBLICATION NUMBER
CACODYLIC ACID AND SALTS
o Oncogenicity
o Mutagenicity
o Teratogenicity
CARBARYL
o Oncogenicity
o Mutagenicity
o Teratogenicity
o Insufficient evidence to issue a
Special Review.
o Decision Document published 47 FR 20376 on
5/12/82. (NTIS # not available).
Returned to the registration process in
12/81 with the stipulation that pursuant
to section 3(c)(2)(B), data on the rate of
dermal absorption be submitted,
knapsack/hand sprayer applicators treating
ditch banks and rights-of-way will wear
respirators or masks, and labels recommend
masks for home users employing knapsacks
or hand sprayers. The data has been
submitted and the Agency has not imposed
labeling changes.
o Decision Document published 45 FR
81869 on 12/12/80: NTIS# PB87-
181301. The Agency has returned this
compound to the registration process with
the stipulation that the following
measures be considered: (1) a section
3(c)(2)(B) action that registrants remedy
data gaps identified in pre-special review
and (2) appropriate label changes be made
to minimize exposure to carbaryl. Both
measures were considered in the
reregistration review of this chemical.
CHLORINATED ISOCYANURATES
o Kidney Effects
o The Agency concluded in the
Registration Standard that chlorinated
isocyanurates do not exceed the risk
criteria for adverse effects in 40 CFR
154.7.
1-22
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FINAL DETERMINATION ON PRE-SPECIAL REVIEWS
(Returned to the Registration Process)
40 CFR 154.7
CRITERIA OF CONCERN
DATE OF FR NOTICE
AND NTIS PUBLICATION NUMBER
CHLOROFORM
o Oncogenicity
o PD 1 published 41 FR 14588 on 4/6/76;
comment period closed 7/23/76. (NTIS #
not available).
o The Agency determined that applicator
exposure had been reduced to a minimum as
a result of label amendments. Also,
registrants were required to submit data
to establish tolerances of permissible
residues on raw agricultural commodities.
DIFLUBENZURON (DIMILIN)
o Hazard to Wildlife o RPAR action completed and Decision
Document issued on 3/26/79: NTIS# PB87-
187191. Registrant consented to
restricted use.
o Agency concluded that existing evidence
does not support issuance of a Special
Review.
FLUOROACETAMIDE (COMPOUND 1081)
o Acute Toxicity to
Mammalian and
Avian Species
o Reduction in
Endangered
Species and
Non-Target
o Acute Toxicity
without Antidote
MALEIC HYDRAZIDE
o Oncogenicity
o Mutagenicity
o Reproductive
Effects
o PD 1 published 41 FR 52792 on 12/1/76:
NTIS# PB80-216823.
o PD 2 published 45 FR 13189 on 2/28/80:
NTIStf PB80-216831.
o Chemical returned to registration
process with the restriction that it be
used only in sewers.
o PD 1 published 42 FR 56920 on
10/28/77; comment period closed
12/14/77: NTIS* PB80-216740.
o Decision Document published 48 FR 498 on
1/5/82: NTIS# PB82-240300. This action
returned maleic hydrazide and salts (K-MH,
DEA-MH) to the registration process.
1-23
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FINAL DETERMINATION ON PRE-SPECIAL REVIEWS
(Returned to the Registration Process)
40 CFR 154.7
CRITERIA OF CONCERN
DATE OF FR NOTICE
AND NTIS PUBLICATION NUMBER
MALEIC HYDRAZINE (cont'd)
o All required data have been submitted to
the Agency.
o Registrants decided not to perform similar
tests on DEA-MH. Thus, DEA-MH was
suspended 11/81.
METHANE ARSONATES
(includes Amine Me thanear senate, Calcium Acid Methanear senate
(CAMA) / Monodosodium Methanearsonate (M8MA) , Di sodium
Methanearsonate (DM8A) )
o Oncogenicity
o Mutagenicity
o On 6/28/83 the pre-Special Review for
methanearsonate chemicals was completed
and a decision memorandum approved
returning these chemicals to the
registration process. The existing
evidence was inadequate to initiate a
Special Review.
o 3(c)(2)(B) letter sent 9/26/83 requiring a
chronic feeding, oncogenicity, teratology,
and applicator exposure studies in order
to determine if there are any risk
concerns .
NALED
o Mutagenicity
o Fetotoxicity
o Reproductive
Effects
o Chemical returned to the registration
process on 6/30/83. Based on a review of
all available data, no valid tests or
definitive evidence exist which meet or
exceed the Special Review risk criteria.
OBPA (10,10'-Oxybisphenoxarsine)
o Oncogenicity
o Mutagenicity
o Teratogenicity
o Decision Document issued 4/9/79.
(NTIS # not available) . Returned
to the registration process due to lack of
evidence of oncogenicity in the suspected
arsenical compound.
1-24
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FINAL DETERMINATION ON PRE-SPECIAL REVIEWS
(Returned to the Registration Process)
40 CFR 154.7
CRITERIA OF CONCERN
DATE OF FR NOTICE
AND NTI8 PUBLICATION NUMBER
PARAQUAT BICHLORIDE
o Emergency
Treatment
o Chronic Effects
o Decision Document published 47 FR
45075 on 10/23/82: NTIS# PB87-181392.
Outlined data gaps and voluntary
cancellation of certain non-crop use
sites.
PIPERONYL BUTOXIDE
o Oncogenicity
ROTENONE
o Oncogenicity
o Mutagenicity
o Teratogenicity
o Reproductive
Effects
o Chronic Effects
o Significant Wild-
life Population
Reductions
o Acute Toxicity to
Aquatic Wildlife
TERBUTRYN
o Oncogenicity
o Mutagenicity
o Reproduction
o Decision Document published 47 FR 20376 on
5/12/82: NTISfl PB83-137901. Chemical
returned to the registration process and a
section 3(c)(2)(B) notice requesting
additional data issued on 9/30/82.
o Studies received 8/87 and reviewed 4/8/88
by Toxicology Branch.
o Decision Document published 46 FR
36745 on 7/15/81 (NTIS # not available)
Chemical returned to the registration
process based on a finding of no
unreasonable adverse effects.
able adverse effects.
o Decision Document published 47 FR
20376 on 5/12/82. (NTIS # not
available).
o Chemical returned to the registration
process. Registrants agreed to change
label to reduce applicator risk to
acceptable levels.
1-25
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FINAL DETERMINATION ON PRE-SPECIAL REVIEWS
(Returned to the Registration Process)
40 CFR 154.7
CRITERIA OF CONCERN
DATE OF FR NOTICE
AND NTI8 PUBLICATION NUMBER
TRIALLATE
o Oncogenicity
o Mutagenicity
include the data
o
needs.
o Decision Document published 45 FR
92349 on 12/15/80 (NTIS # not available).
The Agency determined that, in light of
the low level of exposure, the chemical
should be returned to the registration
process stipulating that a section
3(c)(2)(B) action be initiated to obtain
necessary toxicity data to evaluate its
hazards.
3(c)(2)(B) was issued on 6/15/84 to
8,8,S-TRIBUTYL PHOSPHOROTRITHIOATE
o Neurotoxicity
o Decision Document published 47 FR
20376 on 5/12/82: NTISfl PB87-
186789.
o Returned to the registration process based
on a finding of no unreasonable adverse
effects. Registrants agreed to protective
clothing requirement.
TRIBUTYL PHOSPHOROTRITHIOITE
o Neurotoxicity
TRICHLORFON
o Oncogenicity
o Mutagenicity
o Teratogenicity
o Reproductive
Effects
o Decision Document published 47 FR
20376 on 5/12/82: NTIS# PB87-
186797.
o Returned to the registration process
based on a finding of no unreasonable
adverse effects. Registrants agreed to
protective clothing requirement.
o Removed from Pre-Special Review as
it chemically relates to dichlorvos.
(See Dichlorvos.)
o FetotoxicityoExisting evidence does not
support issuance of a Special Review for
this chemical.
1-26
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FINAL ACTION
VOLUNTARY CANCELLATIONS
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FR NOTICE
AND NTI8 PUBLICATION NUMBER
ACRYLONITRILE
o Oncogenicity
o Teratogenicity
o Neurotoxicity
ARSENIC TRIOXIDE
o Oncogenicity
o Mutagenicity
o Teratogenicity
BENZENE
o Oncogenicity
o Mutagenicity
o Blood Disorders
BHC
o Oncogenicity
CAPTAFOL
o Oncogenicity
CARBON TETRACHLORIDE
O 43 FR 26310 (6/19/78). Three
products only.
o 42 FR 45944 (9/13/77). Some uses
were cancelled.
o All products voluntarily cancelled
on 7/31/85.
o 43 FR 31432 (7/21/78). NTIS# PB80-216781.
o All products voluntarily cancelled
5/15/87.
o Oncogenicity o 50 FR 42997 (10/23/85). Many products
o Toxic Effects on cancelled.
Liver and Kidneys
CHLORANIL
o Oncogenicity
CHLORDAKE
o Oncogenicity
O 42 FR 3702 (1/19/77)
o Major registrant Velsicol agreed on
8/11/87 to cancel some termiticide
products and withdraw all others unless
indoor air moni-toring studies showed no
detectable levels.
o 53 FR 11798 (4/8/88) announced
cancellation of many termiticide products
1-27
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FINAL ACTION
VOLUNTARY CANCELLATIONS
40 CFR 154.7 CRITERIA DATE OF FR NOTICE
POSSIBLY MET OR EXCEEDED AND NTIS PUBLICATION NUMBER
CHLORDANE (cont'd)
and termination of sale, distribution, and
use (except by homeowners) as of 4/15/88.
All remaining products are withdrawn or
suspended under section 3(c)(2)(B).
CHLORDIMEFORM
o Oncogenicity o Proposed decision not to initiate Special
Review due to voluntary cancellation of
all products published 53 FR 36422 on
9/19/88.
o Final decision published 54 FR 6242 on
2/8/89 allowed use of existing stocks by
end users until 10/1/89.
COPPER ACETOARSENITE
o Oncogenicity o 42 FR 18422 (4/7/77).
o Mutagenicity
o Teratogenicity
COPPER AR8ENATE
o Oncogenicity o 42 FR 18422 (4/7/77).
(Basic)
CYHEXATIN
o Teratogenicity o All products voluntarily cancelled
9/25/87.
ENDRIN
o Reduction in o Cancellation of all uses except one
Endangered effective 9/12/85.
Species
and Non-Target
Species
EPN (Ethyl(p-nitrophenyl)thiobenzene phosphonate)
o Neurotoxicity o All products voluntarily cancelled
o Hazard to Aquatic on 7/24/87.
Organisms
1-28
-------
FINAL ACTION
VOLUNTARY CANCELLATIONS
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FR NOTICE
AND NTI8 PUBLICATION NUMBER
ERBON
o Oncogenicity
o Teratogenicity
o Fetotoxicity
HEPTACHLOR
o Oncogenicity
MONOCROTOPHOS
o Avian Effects
MONURON
o Oncogenicity
NITROFEN (TOK)
o Teratogenicity
o Mutagenicity
o Oncogenicity
o 45 FR 58770 (10/4/80).
o Major registrant Velsicol agreed on
8/11/87 to cancel some termiticide
products and withdraw all others unless
indoor air monitoring studies showed no
detectable levels.
o 53 FR 11798 (4/8/88) announced
cancellation of many termiticide products
and termination of sale, distribution, and
use (except homeowner products) as of
4/15/88. All remaining products are
withdrawn or suspended under section
3(0) (2) (B).
o All products voluntarily cancelled on
7/15/88.
o 42 FR 41320 (8/16/77). Some products
cancelled.
o All products voluntarily cancelled
on 9/15/83.
OMPA (Octamethylpyrophosphoramide)
o Oncogenicity o 41 FR 21859 (5/28/76).
PERTHANE
o Oncogenicity
o 45 FR 41694 (6/20/80). Many products
cancelled.
1-29
-------
FINAL ACTION
VOLUNTARY CANCELLATIONS
40 CFR 154.7 CRITERIA DATE OF FR NOTICE
POSSIBLY MET OR EXCEEDED AND NTIS PUBLICATION NUMBER
PHENAR8AZINE CHLORIDE
o None o 42 FR 59776 (11/21/77).
RONNEL
o Oncogenicity o 51 FR 2953 (1/22/86). Many products
cancelled.
8AFROLE
o Oncogenicity o 42 FR 11039 (2/25/77).
o Mutagenicity o 42 FR 16844 (3/30/77).
o 42 FR 29957 (6/10/77).
SODIUM ARSENITE
o Oncogenicity o 43 FR 48267 (10/18/78).
o Mutagenicity Two products cancelled.
o Teratogenicity
STROBANE
o Oncogenicity o 41 FR 26607 (6/28/76).
2,4,5-TRICHLOROPHENOL
o Oncogenicity o Most product cancelled in
o Fetotoxicity response to May 1, 1985 data call-in
notice
TRY8BEN
o Oncogenicity o 43 FR 5782 (2/9/78).
1-30
-------
CANCELLATIONS ISSUED PRIOR TO RPAR/SPECIAL REVIEW PROCESS
40 CFR 154.7 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FR NOTICE
AND NT IS PUBLICATION NUMBER
ALDRIN
o Carcinogenicity
o Bio-accumulation
o Hazard to Wildlife
o Other Chronic
Effects
CHLORDANE/HEPTACHLOR
o Carcinogenicity
o Reductions in
Non-target and
Endangered Species
CHLORDECONE (KEPONE)
o Oncogenicity
o 39 FR 37246 (10/18/74).
Cancellation of all but termiticide
and use.
o 43 FR 12372 (3/24/78) . Cancellation
of all but termiticide use.
DDD (TDE)
o 42 FR 18885 (4/11/77) and 42 FR
38205 (7/27/77). NTIS# PB80-216773.
(Dichlorodiphenyl dichloroe thane)
o Carcinogenicity
o Bio-accumulation
o Hazard to Wildlife and
Other Chronic Effects
o 36 FR 5254 (3/18/71) .
DDT (Dichlorodiphenyl trichloroethane)
o Carcinogenicity o 37 FR 13369 (7/7/72) .
o Bio-accumulation of most uses.
o Hazard to Wildlife
and Other Chronic
Effects
Cancellation
DIELDRIN
o Carcinogenicity o 39 FR 37246 (10/18/74).
o Bio-accumulation Cancellation of all but termiticide
o Hazard to Wildlife and use.
o Other Chronic Effects
MIREX
o Carcinogenicity
o Bio-accumulation
o Hazard to Wildlife
and Other Chronic Effects
o 41 FR 56703 (12/29/76) .
1-31
-------
Status
of
Registration Standards in the Reregistration Program
December 1989
Office of Pesticide Programs
U.S. Environmental Protection Agency
Washington, D.C. 20460
-------
Rereqistration Process
In response to the mandate by Congress to reregister all
previously registered pesticide products [FIFRA section 3(g)], EPA
established the Registration Standards process in 1980. A
Registration Standard states EPA's evaluation of existing data and
identifies incomplete or additional data requirements that
registrants must fulfill in order to reregister a pesticide
product. The aim of this process is to reevaluate the active
ingredients in pesticide products in accordance with new standards
for registration.
A review of current scientific data and increased awareness
of potential hazards associated with pesticide use resulted in the
expanded data and labeling requirements promulgated in 1984 (40
CFR Part 158). Data requirements for registration provide data
and information necessary to assess the identity, composition,
potential adverse effects, and environmental fate of each
pesticide. Data may be required from any or all of the following
categories: 1) Product and Residue Chemistry; 2) Environmental
Fate; 3) Toxicology; 4) Reentry Protection; 5) Spray Drift; 6)
Wildlife and Aquatic Organisms; 7) Plant Protection; 8) Non-Target
Organisms; and 9) Product Performance.
After all additional data have been received and reviewed by
the Agency, the Registration Standard outlining EPA's regulatory
position on the active ingredient under review is determined. If
the data analysis indicates that a Special Review criterion has
been met (40 CFR Part 154.7), the Registration Standard announces
the Agency's decision regarding issuance or consideration of a
Special Review for some or all uses of the chemical.
The FIFRA Amendments of 1988 mandate a comprehensive data
call-in and accelerated reregistration process, to be implemented
in five phases over a nine-year period. The amendments serve to
expedite the reregistration process and development of Registration
Standards. The phased approach delineates a time frame for
completion of the data base for each pesticide product, evaluation
of all data by the Agency and reregistration of products. The
responsibility for making data available lies with pesticide
registrants.
The five phases of the reregistration process are: 1)
Identification and categorization of active ingredients requiring
reregistration. Only pesticides registered between November 1,
1984 and December 24, 1988 for which there are no outstanding
requirements are exempt from the accelerated reregistration
process. The Agency will publish four lists (A, B, C, and D) of
active ingredients which are categorized by the priorities outlined
in FIFRA section 4(c)(l). Registrants receive lists of active
ingredients and dates for required response. 2) Registrants notify
2-1
•II
-------
the Agency of their decision to reregister pesticide products.
Registrants identify data gaps or additional data requirements and
make a commitment to provide the neces-sary data. 3) Registrants
submit data summaries and reformatted versions of selected,
previously submitted data. 4) The Agency reviews data and
information gathered during Phases 2 and 3. Registrants are
notified of any additional data requirements and are expected to
make a commitment to satisfy the Agency's requests. 5) The Agency
reviews all data and determines whether the pesticide products
containing the active ingredient are to be reregistered, or if
other regulatory action is appropriate. Time periods for
completing each of the five phases are discussed in FIFRA section
4(b-g).
The subsequent pages list in alphabetical order: 1)
Registration Standards which have been issued; and 2) Registration
Standards which are scheduled to be issued.
2-2
-------
REGISTRATION STANDARDS ISSUED
CHEMICAL j TYPE
Acephate
ADBAC (Hyamine 3500)
Volume 2
Alachlor
Aldicarb
Aldrin
Aliette
OF CHEMICAL j DATE OF STANDARD!
Insecticide
Disinfectant
Herbicide
Insecticide
Insecticide
Fungicide
September 1987
September 1985
1987
November 1984
March 1984
December 1986
June 1983
NTIS NUMBER
PB88-131362
PB86-169406
PB87-138749
PB86-179835
PB84-207653
PB87-183778
PB84-206564
December 1986 Not Available
Allethrin
Stereoisomers
Aluminum Phosphide
4-Aminopyridine
Amitraz
Amitrole
Ammonium Sulfamate
Anilazine
Arsenic Acid
Arsenic, Chromium &
Chromated Arsenical
Compounds
Aspon
Asulam
Atrazine
Az inphos-Methy1
Bacillus
Thuringiensis
Insecticide
Insecticide
Bird, Chemo-
sterilants,
Toxicants and
Repellents
Insecticide
Herbicide
Herbicide
Herbicide
Herbicide
Wood
Preservative
Insecticide
Herbicide
Herbicide
Insecticide
Insecticide
2-3
March 1988
November 1981
October 1986
PB88-215231
PB82-137514
PB87-117172
September 1980 PB84-209907
October 1987
March 1984
April 1981
December 1983
September 1986
June 1988
September 1980
December 1987
September 1983
September 1986
September 1986
December 1988
PB88-128665
PB87-104766
PB82-133570
PB84-168301
PB87-101572
PB89-102842
PB84-206549
PB88-168588
PB84-149541
PB87-111779
Not Available
PB89-164198
-------
REGISTRATION STANDARDS ISSUED
CHEMICAL
TYPE OF CHEMICAL { DATE OF STANDARD { NTIS NUMBER
Barium Metaborate
Bendiocarb
Benomyl
Bentazon
Bifenox
BKLFI-2
Boric Acid & Salts
Bromacil
Brominated
Salicylanilide
Butoxycarboxim
Butylate
Captafol
Captan
Carbaryl
Carbofuran
Carbophenothion
Carboxin
Chloramben
Chlordane
Chlordimeform HC1
Chlorinated
Isocyanurates
Chlorobenz ilate
*Issued as a draft
Fungicide
Insecticide
Fungicide
Herbicide
Herbicide
Disinfectant
Insecticide
Herbicide
Disinfectant
Insecticide
Herbicide
Fungicide
Fungicide
Insecticide
Insecticide
Insecticide
Fungicide
Herbicide
Insecticide
Insecticide
Disinfectant
Insecticide
standard
July 1983
October 1987
June 1987
September 1985
June 1981
September 1981
November 1985
September 1982
December 1985
PB84-168376
PB89-164172
PB89-100150
PB86-159563
PB83-138818
PB82-172263
PB87-101903
PB87-110276
PB86-168150
December 1981 PB82-177585
September 1983
*March 1989
September 1984
March 1986
March 1984
July 1984
May 1984
August 1981
July 1981
December 1986
*1985
May 1988
PB85-147304
Not Available
PB87-104774
PB86-181674
PB84-232602
PB87-105516
PB87-114229
PB82-132994
PB82-134347
PB87-175816
Not Available
PB88-220660
December 1983 PB85-107605
2-4
-------
REGISTRATION STANDARDS ISSUED
CHEMICAL
Chloroneb
Chloropicrin
Chlorothalonil
Chlorpropham
Chlorpyrifos
Chiorsulfuron
TYPE OF CHEMICAL ! DATE OF STANDARD! NTIS NUMBER
Fungicide
Insecticide
Fungicide
Herbicide
Insecticide
Herbicide
Chromated & Non- Wood
Chromated Arsenicals Preservative
Coal Tar/Creosote
Copper Compounds
[Group II]
Copper Sulfate
Coumaphos
Cryolite
Cyanazine
Cycloheximide
Cyhexatin
2,4-D
Dalapon
Daminozide
2,4-DB
DCNA
Wood
Preservative
Fungicide
Fungicide
Insecticide
Insecticide
Herbicide
Fungicide
Insecticide
Herbicide
Herbicide
Herbicide
Herbicide
Herbicide
September 1980
December 1982
October 1984
*September 1988
PB81-123804
PB86-182094
PB85-247245
Not Available
December 1987 PB88-169917
September 1984
*June 1989
PB87-110284
Not Available
September 1982 PB85-122505
September 1986
1989
April 1988
April 1987
March 1986
August 1981
September 1989
June 1983
April 1988
December 1984
September 1982
June 1985
September 1988
July 1987
June 1984
September 1988
December 1983
PB87-114088
PB89-102842
PB88-225255
PB87-190344
PB86-236767
PB82-133357
Not Available
PB84-211945
PB88-216866
PB86-175098
PB84-211945
PB86-173184
PB89-102396
PB88-112370
PB87-104782
PB89-114177
PB84-210178
*Issued as a draft standard.
2-5
-------
REGISTRATION STANDARDS ISSUED
CHEMICAL
TYPE OF CHEMICAL ! DATE OF STANDARD! NTIS NUMBER
DCPA
DEET
Demeton
Dialifor
Diallate
Diazinon
Dicamba
Dichlobenil
Dichlone
1,3-Dichloropropene
Dichlorvos
Dicofol
Dicrotophos
Difenzoquat
Diflubenzuron
Dimethoate
Dioxathion
Diphenamid
Dipropetryn
Diquat Dibromide
Disulfoton
Diuron
Dodine
2,4-DP
Endosulfan
Herbicide
Insecticide
Insecticide
Insecticide
Herbicide
Insecticide
Herbicide
Herbicide
Fungicide
Nematicide
Insecticide
Insecticide
Insecticide
Herbicide
Insecticide
Insecticide
Insecticide
Herbicide
Herbicide
Herbicide
Insecticide
Herbicide
Disinfectant
Herbicide
Insecticide
June 1988
December 1980
February 1985
August 1981
March 1983
December 1988
September 1983
March 1987
January 1981
September 1986
September 1987
December 1983
April 1982
December 1988
September 1985
March 1983
March 1983
June 1987
June 1985
June 1986
December 1984
September 1983
February 1987
September 1988
April 1982
PB88-225263
PB81-207722
PB86-168820
PB82-133638
PB85-144814
PB89-146294
PB84-243492
PB87-184834
PB81-207383
PB87-111787
PB88-131354
PB84-160084
PB89-190862
PB89-162127
PB86-176500
PB87-110318
PB85-245033
PB88-113162
PB86-171147
PB87-105490
PB86-178167
PB84-210327
PB88-124516
PB89-114086
PB82-243999
2-6
-------
REGISTRATION STANDARDS ISSUED
CHEMICAL
EPN
EPTC
Ethephon
j TYPE OF CHEMICAL |
Insecticide
Herbicide
Growth
Regulator
DATE OF STANDARD' NTIS NUMBER
April 1987 PB87-228474
September 1983 PB87-109427
September 1988 PB89-109474
Ethion
Ethoprop
Ethoxyguin
2-Ethyl-l,3-Hexanediol
Ethyl Parathion
Fenaminosulf
Fenamiphos
Fenitrothion
Fensulfothion
Fenthion
Fluchloralin
Fluometuron
Folpet
Fonofos
Formaldehyde and
Paraformaldehyde
Formetanate HC1
Fumarin
Glyphosate
Heliothis NPV
Insecticide
Nematicide
Growth
Regulator
Insecticide
Insecticide
Fungicide
Fungicide
Insecticide
Insecticide
Insecticide
Herbicide
Herbicide
Fungicide
Insecticide
Disinfectant
Insecticide
December 1982
September 1989
June 1983
June 1988
March 1981
March 1981
December 1986
September 1983
June 1987
July 1987
December 1983
June 1988
June 1985
December 1985
June 1987
March 1984
September 1986
May 1988
PB86-177565
Not Available
PB84-210194
PB88-243977
PB82-131418
PB81-234098
PB87-152120
PB86-177573
PB88-100374
PB88-191697
PB85-148963
PB88-232350
PB86-176476
PB87-109435
PB87-232492
PB84-210186
Not Available
PB88-231543
September 1983 PB84-141456
PB81-123812
Rodent Toxicant September 1980
and Anticoagulant
Herbicide
Insecticide
2-7
July 1986
June 1984
PB87-103214
PB85-134393
-------
REGISTRATION STANDARDS ISSUED
CHEMICAL j TYPE OF CHEMICAL ! DATE OF STANDARD! NTIS NUMBER
Heptachlor
Hexazinone
Isopropalin
Lindane
Linuron
Magnesium Phosphide
Insecticide
Herbicide
Herbicide
Insecticide
Herbicide
Insecticide
December 1986
February 1982
September 1988
August 1981
September 1985
June 1984
February 1982
PB87-175808
PB87-110292
PB89-126080
PB82-131293
PB86-175114
PB85-149011
PB82-195777
Malathion
Maleic Hydrazide
Mancozeb
Maneb
MCPA
MCPP (Mecoprop)
Metalaxyl
Metaldehyde
Methamidophos
Methidathion
Methiocarb
Methomyl
Insecticide
Herbicide
Fungicide
Fungicide
Herbicide
Herbicide
Fungicide
Molluscicide
Insecticide
Insecticide
Insecticide
Insecticide
Methoprene Insecticide
Methoxychlor Insecticide
*Issued as a draft standard
November 1985
October 1986
February 1988
June 1988
April 1987
October 1988
March 1982
September 1989
Not Available
PB87-117172
PB88-184585
PB88-236849
PB88-156419
PB89-124770
PB87-110326
Not Available
December 1988 PB89-172746
August 1981
September 1988
December 1988
September 1982
January 1983
*1989
March 1987
September 1981
April 1989
February 1982
December 1988
PB82-172297
PB89-128979
PB89-161996
PB87-109419
PB87-109419
Not Available
PB87-190898
PB82-180738
PB89-193957
PB87-109443
PB89-138523
2-8
-------
REGISTRATION STANDARDS ISSUED
CHEMICAL { TYPE OF CHEMICAL { DATE OF STANDARD} NTIS NUMBER
Methyl Bromide
Methyl Parathion
MetIran
Metolachlor
Metribuzin
Mevinphos
Monocrotophos
Monuron
Monuron TCA
Nabam
Naled
Naphthalene
Naphthaleneacetic
Acid and Salts
Naptalam
Nitrapyrin
Norflurazon
OBPA
Oryzalin
Oxamyl
Oxydemeton-Methyl
Oxytetracycline
Paraquat Dichloride
Disinfectant
Insecticide
Fungicide
Herbicide
Herbicide
Insecticide
Insecticide
Herbicide
Herbicide
Fungicide
Insecticide
Insecticide
Growth
Regulator
Insecticide
Herbicide
Herbicide
Fungicide
Herbicide
Insecticide
Insecticide
Fungicide
Herbicide
August 1986
December 1986
October 1988
September 1980
January 1987
June 1985
March 1988
September 1985
July 1983
July 1983
April 1987
June 1983
September 1981
July 1981
1988
March 1985
June 1985
December 1984
October 1981
*June 1987
June 1987
September 1987
December 1988
June 1987
May 1988
PB87-105508
PB87-139432
PB89-124663
PB81-123280
PB87-158853
PB86-174216
PB88-215249
PB86-173895
PB89-193965
PB84-166669
PB88-192745
PB84-158980
PB82-139437
PB82-131145
PB88-180492
PB86-173861
PB86-176468
PB86-135159
PB82-172271
Not Available
PB87-228102
PB89-141071
PB89-138556
PB87-228524
PB88-217005
*Issued as a draft standard
2-9
0-
<\
-------
REGISTRATION STANDARDS ISSUED
CHEMICAL j TYPE OF CHEMICAL ! DATE OF STANDARD! NTIS NUMBER
PCNB
Pendimethalin
Perfluidone
Phenmedipham
Phorate
Phosalone
Phosmet
Phosphamidon
Picloram
Potassium Bromide
Potassium
Fungicide
Herbicide
Herbicide
Herbicide
Insecticide
Insecticide
Insecticide
Insecticide
Herbicide
Disinfectant
Disinfectant
January 1987 PB88-101126
March 1985 PB86-172814
September 1985 PB86-173879
March 1987 PB89-108690
August 1984 PB87-109383
December 1988 PBS 9 -14 13 3 7
September 1981 PB82-131731
November 1987 PB88-148044
September 1986 PB87-116620
December 1987 PB88-174412
March 1985 PB86-173887
September 1988 PB89-159834
September 1984 PB89-187256
September 1985 PB86-173135
Permanganate
Prometryn
Pronamide
Propachlor
Propanil
Propargite
Propazine
Propham
Resmethrin
Rotenone
Simazine
Sodium and Calcium
Hypochlorites
Herbicide
Herbicide
Herbicide
Herbicide
Insecticide
Herbicide
Herbicide
Synthetic
Pyrethroid
Insecticide
Herbicide
Disinfectant
2-10
March 1987
April 1986
December 1984
December 1987
September 1986
December 1988
March 1987
December 1988
PB87-184826
PB87-103735
PB86-174182
PB88-167010
PB87-139358
PB89-162101
PB87-202347
PB89-164214
October 1988 PB89-173736
March 1984 PB84-212349
February 1986 PB87-103222
-------
REGISTRATION STANDARDS ISSUED
CHEMICAL
! TYPE OF CHEMICAL ! DATE OF STANDARD! NTIS NUMBER
Sodium Omadine
Streptomycin
Sulfotepp
Sulfur
Sulfuryl Fluoride
Sulprofos
Sumithrin
Tebuthiuron
Temephos
Terbacil
Terbufos
Terbutryn
Terrazole
Tetrachlorvinphos
Thiophanate-Ethyl
Thiophanate-Methyl
Thiram
TPTH
Trichlorfon
Trifluralin
Trimethacarb
Vendex
*Issued as a draft
Disinfectant
Fungicide
Insecticide
Fungicide
Disinfectant
Insecticide
Insecticide
Herbicide
Insecticide
Herbicide
Insecticide
Herbicide
Fungicide
Insecticide
Fungicide
Fungicide
Fungicide
Fungicide
Insecticide
Herbicide
Insecticide
Insecticide
standard
July 1985
September 1988
September 1988
December 1982
June 1985
August 1981
November 1987
July 1987
August 1981
May 1982
August 1989
June 1983
September 1988
September 1986
September 1980
October 1988
December 1985
*October 1986
June 1984
September 1984
June 1984
April 1987
September 1985
March 1987
PB86-173929
PB89-129738
PB89-128995
PB86-102043
PB86-173937
PB82-133646
PB88-156732
PB87-235016
PB82-140641
PB85-120186
PB90-107079
PB84-210335
PB89-109490
PB87-143038
PB81-126716
PB89-126056
PB87-101283
Not Available
PB85-102705
PB85-248797
PB85-149300
PB87-201935
PB86-169414
PB87-190690
2-11
-------
REGISTRATION STANDARDS ISSUED
CHEMICAL I TYPE OF CHEMICAL j DATE OF STANDARD] NTIS NUMBER,
Warfarin & Sodium Salt Rodent Toxicant August 1981 PB82-140716
and Anti- *April 1989 Not Available
coagulant
Zinc Phosphide Rodent Toxicant June 1982 PB85-102499
and Anticoagulant
*Issued as a draft standard
2-12
-------
REGISTRATION STANDARDS SCHEDULED TO BE ISSUED
CHEMICAL
! TYPE OF CHEMICAL !
EXPECTED DATE
Atrazine
Chlorothalonil
Simazine
Herbicide
Fungicide
Herbicide
Second Round Review still
in progress.
The final standard (FRSTR)
is scheduled to be signed
during the first quarter of
FY '90.
Second Round Review still
in progress.
Warfarin & Sodium Rodent Toxicant The final standard (FRSTR)
Salt and Anticoagulant is scheduled to be issued
during the first quarter of
FY '90.
2-13
-------
REPORT ON THE STATUS
OF
CHEMICALS IN THE SPECIAL REVIEW PROGRAM
AND
REGISTRATION STANDARDS IN THE REREGISTRATION PROGRAM
Index
1080 1-19
1081 1-23
Acephate 2-3
Acrylonitrile 1-27
ADBAC (Hyamine 3500) 2-3
Alachlor 1-3, 2-3
Aldicarb 1-3, 2-3
Aldrin 1-31, 2-3
Aliette 2-3
Allethrin Stereoisomers 2-3
Aluminum Phosphide 2-3
Amine Methanearsonate 1-24
4-Aminopyridine 2-3
Amitraz 1-8, 2-3
Amitrole 1-3, 2-3
Ammonium Sulfamate 2-3
Amobam 1-14
Anilazine 2-3
Arsenic Acid 1-5, 2-3
Arsenic, Chromium and Chromated Arsenical Compounds 2-3
Arsenic Trioxide 1-27
Aspon 2-3,
Asulam 2-3
Atrazine 2-3, 2-13
Azinphos-Methyl 2-3
Bacillus Thuringiensis 2-3
Barium Metaborate 2-4
Bendiocarb 2-4
Benomyl 1-8, 2-4
Bentazon 2-4
Benzene 1-27
BHC 1-27
Bifenox 2-4
BKLFI-2 2-4
Boric Acid 2-4
Bromacil and Salts 2-4
Brominated Salicylanilide 2-4
Butoxycarboxim 2-4
Butylate 2-4
Cacodylic Acid and Salts 1-22
Cadmium 1-8
Calcium Acid Methanearsonate (CAMA) 1-24
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Calcium Arsenate 1-5
Calcium Hypochlorite 2-10
Captafol 1-9, 1-27, 2-4
Captan 1-9, 2-4
Carbaryl 1-22, 2-4
Carbofuran 1-3, 2-4
Carbon Tetrachloride 1-9, 1-27
Carbophenothion 2-4
Carboxin 2-4
Chloramben 2-4
Chloranil 1-27
Chlordane 1-27, 1-31, 2-4
Chlordecone (Kepone) 1-31
Chlordimeform 1-28
Chlordimeform HC1 2-4
Chlorinated Isocyanurates 1-22, 2-4
Chlorobenzilate 1-10, 2-4
Chloroform 1-23
Chloroneb 2-5
Chloropicrin 2-5
Chlorothalonil 2-5, 2-13
Chlorpropham 2-5
Chlorpyrifos 2-5
Chlorsulfuron 2-5
Chromated and Non-Chromated Arsenicals 2-5
Coal Tar 1-10, 2-5
Compound 1080 (Sodium Fluoroacetate) 1-19
Compound 1081 (Fluoroacetamide) 1-23
Copper Acetoarsenite 1-28
Copper Arsenate (Basic) 1-28
Copper Compounds [Group II] 2-5
Copper Sulfate 2-5
Coumaphos 2-5
Creosote 1-10, 2-5
Cryolite 2-5
Cyanazine l-ll/ 2-5
Cycloheximide 2-5
Cyhexatin 1-28, 2-5
2,4-D 1-4, 2-5
Dalapon 2-5
Daminozide 1-4, 2-5
2,4-DB 1-4, 2-5
DBCP 1-1?.
DCNA 2-5
DCPA 2-6
DDD (TDE) 1-31
DDT 1-31
DDVP 1-4, 2-6
DEBT 2-6
Demeton 2-6
Dialifor 2-6
Diallate 1-12, 2-6
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Diazinon 1-12/ 2-6
Dibromochloropropane (DBCP) 1-11
Dicamba 2-6
Dichlobenil 2-6
Dichlone 2-6
1,3-Dichloropropene 1-4, 2-6
Dichlorvos (DDVP) 1-4, 2-6
Dicofol 1-12, 2-6
Dicrotophos 2-6
Dieldrin 1-31
Difenzoquat 2-6
Diflubenzuron 1-23, 2-6
Dimethoate 1-13, 2-6
Dimilin 1-23
Dinocap 1-13
Dinoseb 1-13
Dioxathion 2-6
Diphenamid 2-6
Dipropetryn 2-6
Diguat Dibromide 2-6
Disulfoton 2-6
Diuron 2-6
Dodine 2-6
2,4-DP 1-4, 2-6
DSMA (Disodium Methanearsonate) 1-24
EBDCs (Ethylenebisdithiocarbamates) 1-5, 1-14
EDB (Ethylene Dibromide) 1-14
Endosulfan 2-6
Endrin 1-14, 1-28
EPN (Ethyl(p-nitrophenyl)thiobenzene phosphonate) 1-14, 1-28, 2-7
EPTC 2-7
Erbon 1-29
Ethalfluralin 1-15
Ethephon 2-7
Ethion 2-7
Ethoprop 2-7
Ethoxyquin 2-7
Ethylene Dibromide (EDB) 1-15
Ethylene Oxide 1-5
2-Ethyl-l,3-Hexanediol 2-7
Ethyl Parathion 2-7
Fenaminosulf 2-7
Fenamiphos 2-7
Fenitrothion 2-7
Fensulfothion 2-7
Fenthion 2-7
Fluchloralin 2-7
Fluometuron 2-7
Fluoroacetamide (Compound 1081) 1-23
Folpet 2-7
Fonofos 2-7
Formaldehyde 2-7
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Formetanate HC1 2-7
Fumarin 2-7
Glyphosate 2-7
Goal 1-16
Heliothis NPV 2-7
Heptachlor 1-29, 1-31, 2-8
Hexazinone 2-8
Hypochlorites, Sodium and Calcium 2-10
Inorganic Arsenicals (non-wood use) 1-5
Inorganic Arsenicals (wood use) 1-16
Isopropalin 2-8
Kepone (Chlordecone) 1-31
Lead Arsonate 1-5
Lindane 1-16, 2-8
Linuron 1-17, 2-8
Magnesium Phosphide 2-8
Malathion 2-8
Maleic Hydrazide 1-23, 2-8
Mancozeb 1-5, 1-14, 2-8
Maneb 1-5, 1-14, 2-8
MCPA 2-8
MCPP 2-8
Metalaxyl 2-8
Metaldehyde 2-8
Methamidophos 2-8
Methanearsonates 1-24
Methidathion 2-8
Methiocarb 2-8
Methomyl 2-8
Methoprene 2-8
Methoxychlor 2-8
Methyl Bromide 2-9
Methyl Parathion 2-9
Metiram 1-5, 1-14, 2-9
Metolachlor 2-9
Metribuzin 2-9
Mevinphos 2-9
Mirex 1-31
Monocrotophos 1-29, 2-9
Monuron 1-29, 2-9
Monuron TCA 2-9
MSMA (Monodosodium Methanearsenate) 1-24
Nabam 1-5, 1-14, 2-9
Naled 1-24, 2-9
Naphthalene 2-9
Naphthaleneacetic Acid and Salts 2-9
Naptalam 2-9
Nitrapyrin 2-9
Nitrofen (TOK) 1-29
Norflurazon 2-9
OBPA (10,10'-Oxybisphenoxarsine) 1-24, 2-9
OMPA (Octamethylpyrophosphoramide) 1-29
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Oryzalin 2-9
Oxamyl 2-9
Oxydemeton-Methyl 2-9
Oxyfluorfen (Goal) 1-16
Oxytetracycline 2-9
Paraquat Dichloride 1-25, 2-9
PCNB (Pentachloronitrobenzene) 1-17, 2-10
Pendimethalin 2-10
Pentachlorophenol (non-wood use) 1-6
Pentachlorophenol and Derivatives (wood use) 1-17
Perfluidone 2-10
Perthane 1-29
Phenarsazine Chloride 1-30
Phenmedipham 2-10
Phorate 2-10
Phosalone 2-10
Phosmet 2-10
Phosphamidon 2-10
Picloram 2-10
Piperonyl Butoxide 1-25
Potassium Bromide 2-10
Potassium Permanganate 2-10
Prometryn 2-10
Pronamide 1-18, 2-10
Propachlor 2-10
Propanil 2-10
Propargite 2-10
Propazine 2-10
Propham 2-10
Resmethrin 2-10
Ronnel 1-30
Rotenone 1-25, 2-10
Safrole 1-30
Salicylanilide, Brominated 2-4
Silvex 1-20
Simazine 2-10, 2-13
Sodium Hypochlorite 2-10
Sodium Arsenate 1-5
Sodium Arsenite 1-5, 1-30
Sodium Fluoroacetate (1080) 1-19
Sodium Omadine 2-11
Streptomycin 2-11
Strobane 1-30
Strychnine/Strychnine Sulfate 1-19
Sulfotepp 2-11
Sulfur 2-11
Sulfuryl Fluoride 2-11
Sulprofos 2-11
Sumithrin 2-11
2,4,5-T/Silvex 1-20
TCP (2,4,5-Trichlorophenol) 1-21, 1-28
TDE 1-31
Tebuthiuron 2-11
Temephos 2-11
Terbacil 2-11
Terbufos 2-11 xj/
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Terbutryn 1-25, 2-11
Terrazole 2-11
Tetrachlorvinphos 2-11
Thiophanate-Ethyl 2-11
Thiophanate-Methyl 1-20, 2-11
Thiram 2-11
TOK 1-29
Toxaphene 1-20
TPTH 1-6, 2-11
Triallate 1-26
S,S,S-Tributyl Phosphorotrithioate 1-26
Tributyl Phosphorotrithioite 1-26
Tributyltins 1-7
Trichlorfon 1-26, 2-11
2,4,5-Triqhlorophenol (TCP) 1-21, 1-30
Trifluralin 1-21, 2-11
Trimethacarb 2-11
Triphenyltin Hydroxide 1-6
Trysben 1-30
Vendex 2-11
Warfarin and Sodium Salt 2-12, 2-13
Zinc Phosphide 2-12
Zineb 1-5, 1-14
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