RISK ASSESSMENT FOR CHIDRINA1ED PARAFFINS:






       EFFECTS ON FISH AND WILDLIFS
 Health and Environmental Review Division



       Environmental Effects Branch



            Toxicology Section
            December 18, 1985

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                                        1
         . -.  FREUMINAPY TJJSK ASSESSMENT ON CHLORINfflED n-EARAFFINS
 EXECUTIVE SUMMARY
      The following risk assessment is limited to 58 percent chlorinated, short
 chain-length (Cio-13) tv-paraffins.  Ihe chemical/physical, exposure, and
-toxicological data were obtained mostly frcm open literature and reports
 submitted by the Chlorinated Paraffins Consortium.  Predicted jresidue levels
 for the three scenarios are frcm a contract report ty Versar inc. *hich used
 used releases estimated tsy PEI Associates, Inc.* -, Sunmary of the important
 information in this risk .assessment are as follows:
  -»  - o  Production levels for 1983 was 67 million pounds to be used in a wide
         variety of products.  Releases from manufacture, reformulation, use,
     •--,. .-and disposal are estimated to l>e 50 million pounds per year.
      o  Chloroparaffins are highly persistent, have low water solubility, sorb
         readily to sediments and organic matter, have a high bioconcentration
         potential and sane accumulation between trophic levels in the food web.
      o  Monitoring data indicate -that chloroparaff ins are present at sampling
       -sites near two manufacturing plants .in the U.S. and are wide-spread
       "*: contaminants in the united Kingdom.* ^-Monitoring data also support the
         predicted environmental exposure levels made by Versar Inc.   In some
         cases, residue levels in sediments have even been underestimated.
      o  Chloroparaffins have little acute toxicity to fish, birds, and -mammals,
         but they are highly toxic (less than 1 jng/1) to Crustacea and algae.
         Chronic toxicity in most "test species occurred at levels less than 20
         ug/1 for a wide array of reproductive parameters.  Statistically signi-
         ficant (P=0.05) chronic effects were reported at -levels as low as 2A
       -to 3.1 Ajg/1 -for-four test species. All four studies failed  to identify
         a no-observed-«f f ect level (NOEL).
      o Three scenarios were developed which are representative of -many sites?

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                                  2


  'large and snail rivers; low, high and tidal flows; fresh and estuarine


   areas; and north/south gradients.  Similar effects at other sites may


   be expected.


o  Environmental exposures predicted .in water in the -three scenarios either


   approach or exceed the lowest chronic effect level (0.5 ug/1) leaving


  .little or TK> margin for safety.  The lowest effect level cannot be


   identified due to an absence of NQEL's.in those four test species.


o  Population reductions can be anticipated in all three scenarios among


 -- aquatic species, including iish, zooplankton, Crustacea, molluscs, and


   insect larvae.  Benthic species may be expected to be directly affected


   most by the higher chloroparaffin residues present in the sediments.


Depopulation reductions and loss of some benthic species can be expected


   to adversely affect the availability of food to species higher on the


   food web.  Oyster reductions can also affect water quality, reduce


   primary productivity, and cause losses in the two aquatic habitats.


   Oyster reefs and seagrass beds are important habitats to commercial ly-


 ,- .important shrimp, blue crabs, and sport fishes in the Galveston Bay


   area.  Population reductions will also affect food availability-for


   the numerous aquatic birds which feed on fish and benthic organisms.


o "Jteproduction on aquatic birds in Sugar Creek area may also be adversely


 -affected isy chloroparaff ins in their food, which exceed the NOEL.


   Residue levels in biota approach the NOEL for birds in the Galveston


   Bay area, which is an important nesting and/or feeding area for many


   aquatic birds, including at least four endangered avian species.
                                                           /-

o  Under the scenarios presented, chloroparaffin releases do not pose a


   toxicological barrier to migratory species moving through the area.


o  The extent of the toxic effects on benthic species fron residues in


   sediments and residues bioconcentrated in biota can not be evaluated

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                               3



without additional testing.  Additional tests are also necessary to



determine the no-effeet-level for fish reproduction and chronic  effects



on nysid shrimp and daphnids.

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      A.  Manufacture, Use, and Disposal



      Chlorinated jv-paraffins are a class of chlorinated hydrocarbons having the



 general formula CjjH(2x-y+2) Cly,  They are obtained by chlorination of normal



 paraffins (at least 98 percent linear) and wax fractions.  The talk of the



 manufactured products are based on €12» Cjs, and €24 feedstocks and are 40 to



 70 percent chlorine.  While a chlorinated n-paraf f in product may be clasif ied



 fes Ci2» the actual composition is a range of chain lengths that  average Ci2«



 Chlorinated jv-paraf fins nay i>e liquids or solids with a wide range In



 viscosity.



      The capacity of U.S. manufacturers to produce chlorinated paraffins far



 surpasses the past, present, or expected future demands for .the  compounds.



 During 1983, with -two of the «ight potential producing -plants  closed,  active



 U.S. capacity was -217 million pounds, while demand was only 67 million pounds



 (Long, 1984).



     "There are over 200 camercial products that consist of pure chlorinated



 iv-paraffins.  They are used as extreme-pressure additives in lubrication oils



 and metal cutting' oils, secondary plastinzers and flame xetardants in plastics,



 softeners and flame retardants in rubber, plasticizers in paint,  adhesives,



 sealants,.and chalks (Long, 1984).  Some uses are as fire and  water retardants



 in fabric finishing -and a constitutent in printing inks.  The  National



 Institute for Occupational Safety and Health (NIQSH) has identified over 500



 commercial products that contain chlorinated n-paraff ins as a  constituent  (PEI



.Associates, Inc., 1984).



      B.  Regulatory Status



      Chlorinated n-paraff ins (35-64 % chlorine) were reccranended  for testing by



 the Interagency Ttestrng Committee (Federal Register, 1977) based  on the following



 information:

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                                        5


    1)   1972 production levels of 80 million pounds;                    -  v


    2)   use of these materials on a wide variety of household and paint products,
                                             *

        as well as adhesives and flame retardants;


    3)   estimated release xates of 50 million pounds per year;


    -4)   degenerative-changes in the liver and spleen of mice exposed -to chloro-


        paraffins in a chronic study;


    5)   concerns for human  health effects on carcinogenicity, mutagenicity,


        teratogenicity and  other chronic effects in the absence of data; and


    5)  . the need for a critical .assessment of the biological -Significance of the


  _ .. ~ occurrence of  chlorinated n-paraffin residues in fish and the aquatic


        environment.


     The Environmental TTotection Agency announced in the Federal Register    - *


 (1982) that the EPA. would-not at that -time  propose a section 4(a) rule to


 require health or environmental effects testing of the chlorinated n-paraf fins.


 That decision was based on the acceptance of a  voluntary testing proposal made


 by a consortium of  international manufacturers  of chloroparaffins.  Environmental


 fate jieeds included studies on solubility of four categories and an aerobic and


 anaerobic biodegradatipn tests:  Environmental toxicity tests proposed by the


 Consortium are tiered tests (Federal  Register,  19B2).  Phase 1 tests are 30-60


 day lethal and sublethal studies on mussels and rainbow trout for each of four


 specified test compounds (see Appendix  A).   Phase ~2 tests on the most -toxic


 compound identified in Phase 1 tests  include chronic and bioconcentration tests


 on aquatic invertebrates and fish. The American members of the Consortium also


 agreed to conduct a avian  reproduction  study on mallard ducks.  EPA received


 the environmental toxicity studies from the Consortium in 1984 and the avian


 reproduction  study  in 1985.  All-of the studies have :been reviewed and evaluated


-for scientific soundness and effect levels. "The conclusions from that data


 validation process  have been integrated into an environmental hazard assessment

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                                       6



 (Rabert, 1985).



     Information on releases and predicted environmental txncentrations for an



environmental exposure assessment were prepared by contractors.  PEI Associates,



Inc. (1985) estimated the release levels from manufacture, reformulation, use,



and disposal.  Versar Inc.  (1985) then used those release estimates to prepare



a preliminary exposure assessment for three manufacturing and/or use sites



selected by EPA.  Those three sites are the Schuykill River in Pennsylvania,



Sugar Creek in Ohio, and the Houston Ship Channel/fcalveston Bay, Texas.



III. ENVIRONMENTAL EXPOSURE ASSESSMENT



  A.  Environmental Pate



    . Little environmental fate data are available on chlorinated ji-paraff ins.



The complex nature of the mixtures and the difficult analytical methods needed



to separate and quantify residues have limited the development of information.



Even much of the data that has been developed is of questionable quality.



Chlorinated n-paraffins are generally considered to be persistent.  Chemical



degradation is generally considered insignificant.   Chloroparaffins do-not



hydrolyze, oxidize, £>r otherwise react at significant rates under ambient



temperatures and relatively neutral conditions.



     Data on biodegradation reported by Hildebrecht (1972), Zitko and Arsenalt



(1974 and 1975),-and the Consortium are all inconclusive.  Some biodegradation



.of 58% chlorinated, short chain-length n-paraffins by microorganisms in a 5-day



biochemical oxygen demand (BOD) test was reported by Hildebrecht, but how much



has been strongly debated.  Zitko and Arsenault (1974 and 1975) demonstrated



that microbial degradation in estuarine sediments is faster under anaerobic



conditions than aerobic, but poor recovery of sorbed residues (about 20%)



demonstrated by Raron (1976) and erratic data make quantification of degradation



rates difficult.  Aerobic and anaerobic studies submitted by the Consortium



also indicate little evolution of gases (a measurement of biodegradation)

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                                        7
 for the four -tested mixtures.  In general, it is -thought that dechlorination
 preceeds degradation of the paraffin moiety, tut no information has been
 reported on the identity, persistence, or toxicity of degradates or metabolites.
      Water solubility data .submitted by the Consortium indicate that the chloro-
 paraffin products have low solubility.  Solubility ranges frcn 3.6 — 6.6 ug/1
 (ppb) for the long chain-length mixtures (C2Q-30) ~t° 95 ~ 47° U9/1 ior t*16 short
 chain-length mixtures (Cio-13)-  Insolubility in vater also appears to Increase
 vith increased chlorine content.   The hydrophcbic nature of the chloroparaffins
 Increases the likelihood that residues would readily adsorb to organic matter
 and suspended particles in -both the water column and the sediments at the
 water-sediment interface.
      Campbell and McConnell (1980) found that sediments typically contained
 1000- to 2000-fold higher residue levels than measured in the overlying water
 column,  Ramm (1978)  found that spiked residues were tightly  bound to  sediments,
 such that only about  10-20 percent were recovered  by use of solvents.  Harm
 (1978) concluded from residue data on benthic biota (chironotud larvae and
 worms) that chloroparaf fins residues are accumulated by some  benthic organisms.
      Chloroparaffins  are generally considered to have a low vapor pressure
 (about 1-2 x 10~6 mm  Hg at .20 °C).  Low volatilization of chloroparaf fins would
.indicate low dispersion capability, but residue concentrations in domestic fowl
 and sheep wool-near manufacturing plants (Campbell and McConnell, 1980) suggest
 seme airborne dispersion.  The .range of chloroparaf fin vapor  pressures are not
 too dissimilar from PCB values, which indicates sane potential for atmospheric
 transport to distant  environments.
      Little data exist which demonstrate mobility  and transport  of chlorinated
jt-paraffin residues from-sites-of manufacturing, reprocessing, use, or disposal.
 Very low solubility in water and  low vapor pressure would predict low mobility,
 but monitoring data in the United Kingdom indicate widespread levels of low

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                                       B
contamination in water, sediments, aquatic organisms, and even ccranercial fish
foods.  Analyses of test organisms and food items used in the chronic tests
indicated low levels of short to intermediate chain length chloroparaffins in
rainbow trout (1.3-2.0 ppn), toussels (1.2 ppn), algae (1.8-2.6 ppn)* Artemia
(0.51-0.57 ppn), and fish food pellets (0.78-2.14 ppn) (Harland et al.f 1983).
How residues have spread to contaminate so many of these areas is not yet
aiderstood.
   S.  Environmental Exposure Levels
     3he exposure estimates used in this risk assessment include: extensive
monitoring data collected in the United Kingdom by Campbell and McConnell
(1980); unpublished monitoring data submitted to EPA by Diamond Shamrock for
two sites; and the environmental concentrations estimated by Versar me. at the
three U.S. sites.
   . Campbell and McConnell (1980) reported chloroparaffin residue levels found
in water and sediments from nunerous sites throughout the United Kingdom.  In
general, residue levels show an increase in chlorinated rv-paraff ins ^as river .in
water as Jit passes from the uplands into .industrialized areas, and a decrease
when the river joins the sea.  In the industrial areas, residue levels in the
sediments were 0.1-15.0 ppm, while concentrations in overlying waters ranged
from 0.5 to 6.0 ppb.  Residues in marine and non-marine waters remote from
industrialized areas were frequently -found in either the sediments, -water, or
both. ' The highest residue levels found in a non-industrial area was in the
Sound of Taransay on the remote isle of Harris in the northwestern part of
Scotland.  Residues in water were 2.0 to 4.0 ppb in water and less than the
limit of ijetection in the sediment « 0.05 ppm).  Slightly lower concentrations
•were found at many remote areas throughout the country and Irish Sea.  About
half of the sediment samples from the North Sea contained residues -ranging
from 0.05 to 0.3 ppn.  Residue levels in sediment were about 103- to 104-fold

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 higher than residues an the overlying waters.  Short to intermediate chain-



 J.ength chloroparaffins were usually found in sediments at higher concentrations



 than the longer chain-length mixtures.



    „  Biological samples from 5 aquatic species (plaice and pouting -- two benthic



 fish species, pike - a predatory fish, nussels, and grey seal) collected in the



 rivers and sea in the United Kingdom, indicated chloroparaf fin residues  in all



 species.  Campbell and McOonnell also reported residues in seabirds  (0.5 to 1.2



 ppm) and seabird eggs (< 0.05 to 2 ppm)..  Liver sanples in all three avian



 species and over €6 percent of the eggs contained chloroparaf fins.  Analysis of



 human foodstuffs in the On i ted Kingdom indicated chloroparaf fin  residues .in



 dairy products  (0.3 ppm), vegetable oils and derivatives (0.15 ppm), ..and fruits



 and vegetables  (0.025 ppn).-~ "While no residues were found in tissues of  Welsh



.sheep grazed remote from chloroparaf fin production, sheep grazed in  Weston Point



 near a manufacturing plant contained 0.2 ppm in liver, 0.05 ppm  on mesenteric



 fat and kidney, and no residues found in the heart, lung, or perinephritic fat.



      Monitoring data from the lower Grand River at a Diamond Shamrock manufac-



 turing plant near Plainsville* Ohio indicated significant levels of  chloro-



 paraf fin residues m water, sediments, benthic biota, and plant  roots (Ramm,



 1977).  Residues found in water were about 2 {0.5-3)  ppb with the highest



 concentrations  located at the two sampling sites located just above  and below



 the discharge point.  Residues in the sediments were considerably higher-at-the



 two sampling sites downstream from the discharge point (both 3.1 to  12.6 ppm)



 than the site just above (0.8 ppm).  No residues were detected in several



 species of fish, crayfish, clams, and tadpoles collected at one  or^nore of the



 sites.  Chironomids and/or worms contained residues at all four  sites with the



 highest residues occurring -at the *ite just downstream from the  discharge



 point*  Residues-were also found in the roots of potomogeton at  all  four sites,



 but the residue levels did not correlate-to  sediment levels. The author

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concluded that there was no evidence of residue uptake by many of these species,



but that the strong evidence of accunulation existed in Insect larvae and worm



samples.  The observation was made by the author that "Ihe abundance of insect



larvae, especially in the lower river, was relatively low compared to that of



other similar rivers we have investigated,*



     A pausible interpretation of the irregular pattern of residues in water and



sediments would be that the manufacturing plant is a major source of residues in



the river.  The high residue levels in the sediment indicate adsorption from



discharges over a prolonged period, while the similarity in residue levels in



the water above and below the discharge point was caused by either an occasional



reverse flow up the river :the short distance to the nearby jipstrearo sampling



site possibly due to low flow in the river and high discharge rates or storm



surges from lake Erie.



     Samples taken at the Diamond Shamrock manufacturing site in Houston,  Texas



on the Patrick Bayou also indicated widespread chloroparaffin contamination of



sediments and biota CRamm, 1978).  Only one out of five water samples contained



residues <1~5 ppro) .above the level of detection at 1 ppb.  All 26 sediment



samples contained residues which ranged .Iran 0.15 to 10.0 prnu  Residues found



in biota were 0.10 to 0.52 ppm in whole crabs, 0.2 to 0.42 ppxi in whole



killif ish, and 0.15 ppn in vegetation.  While recovery levels for spiked samples



were moderate for biota samples (70 to 85 percent), recovery ±n sediments  was



quite low (10 to 20 percent).  "While measured sediment levels ranged from 0.2



- 10.O ppm, the low recoveries for spiked sediments would suggest that the



actual sediment concentrations are more probably in the range 1 -^50 ppn."



     "Versar Inc. (1985) predicted environmental concentrations in water,



sediments, and biota for various segments of three aquatic areas near select



manufacturing, reformulating, and/or use sites identified by EPA.  The three



sites were the Schuykill River near Oonchohocken, Pennsylvania; Sugar Creek

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                                                ,*
near Dover, Ohio; and the Houston Ship Channel /Upper Galveston Bay, Texas.  The


release estimates used  in the modelling effort by Versar Inc. were obtained


from tiie report from PEI Associates, Inc.  (1984).  In the absence of release


data on chlorparaffins, PEI Associates made simple assumptions and used flat  '


percentage estimates based on production volumes and use estimates in manufac-


turing, reformulating, packaging, cleaning, and spills.  No release estimates


were made for disposal*  Releases from cleaning were 10 percent, 1.0 percent


from packaging, and 0.01 percent from spills (0.1 percent spilled and 90 percent


pick up with absorbents).


    ~3he residue concentrations of Oilorowax 500-C and Chlorowax 70 predicted


in water, sediment, and biota by Versar Inc. are summarized in Appendix A.


Given  the difference in physical/chemical properties of these two chlorinated


n-paraffins, they assumed that these residue estimates would bracket environ-


mental concentrations for all other chloroparaffin products.   Residue estimates


were made for both controlled and uncontrolled releases.  Controlled releases


assume removal of some residues during wastewater treatment.  Residues in


water  and sediments were each computed as dissolved, sorbed, and total residues.


The assumption that residue concentrations in interstital water would be the


same as residues in the water column provides a minimal value.  One might


expect residue levels in interstitial water to be higher than these estimated


levels based on equilibrium kinetics-with sediment concentrations.  How much


higher is not known.


    C. Summary of Environmental Exposure


     Chloroparaffins are relatively Insoluble in water.  Residues in water


readily sorb to suspended solids and tightly bind to sediments.  Although


chloroparaff ins appear-to toe relatively non-volatile, residues have been found


at sites that indicate atmospheric transport.  Environmental monitoring in the


United ICingdom,'Ohio, and Texas indicate widespread, low-level contamination

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                                        12


 in water* .sediments, aquatic plants and animals, human foodstuffs, and  human


 tissues. Residues in the low parts per million were found to contaminate the

 test organisms and their food sources.  While environmental residue levels

 were generally found highest near .industrialized areas and diminish when .the


 rivers reach the sea, monitoring samples .indicate high residue levels in water


 and sediments in some remote areas.  Residue levels in sediment  are about 1000-

 fold higher than concentrations in  overlying water.  Recovery of residues from


 spiked samples indicate poor recovery (10 to 20 percent). 'Residues Jn .benthic

 organisms and "berrthic fish were higher than residue levels in organisms found

 in the upper water column.


      Modelling of residue releases, transport, and environmental distribution

 at three manufacturing/use sites indicate widespread, low-level  contamination

'. of large areas.  Comparison of the  predicted chloroparaf f in residue levels -at

 three sites (a river, creek, and estuary) indicated the highest  environmental


 concentrations of chloroparaffin would occur in Sugar Creek,  followed by the


 the Houston Ship Channel/Gal veston  Bay area, lexas.  Ihe lowest  chloroparaf fin

 residue levels occurred in the Schuylkill Biver, Pennsylvania are probably due

 to continous flushing and a comparatively high mean stream flow-rate  in-the

 river (2,940-cfs).  Estimated residue levels in the sediments followed the same


 site order.

 IV.  ENVIRONMENTAL HAZARD ASSESSMENT

    -A.  Phase I ana II  —  Consortium Testing


      Information on environmental effects of chlorinated it-paraffins  from .both


 Consortium  sponsored studies and available literature were reviewed in depth by
                                                                 ,>
 EEB iRabert, 1985).  The results of the Consortium's Phase I  and II testing are


 summarized  in Appendix B.  Phase I -testing consisted of 60-day toxicrty tests


 conducted on rainbow trout and bay mussels to identify the aost  toxic mixture of


 four selected chloroparaf fin groupings. - The groupings included  the following

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 combinations of chlorination and chain length: intermediate chlorination (58%)

 and short chain-length (Cio-iah intermediate chlorination 452%) and intermedi-

 ate chain-length (Cj^ij); and one low (42%) and one high (70%) chlorinated,

 Jong chain-length (020-30) mixture.  The results of the Phase _I tests indicated

 that the 38% chlorinated short (Cio-13^ chain-length n-paraffins were more toxic

 than the other three tested chloroparaffin formulations.  However, the testing

 matrix fails, to indicate if it is the most toxic of all chlorinated paraffin

 combinations.  The other mixtures are not without observed chronic effects.

 Dhguantified abnormal behavior were reported for all formulations, especially

 upon mussel filtration (feeding) activity.  The effects indicate that chronic

 effects are "likely to exist for all •formulations.  Bioconcentration factors

 reported in the studies indicate that residues of all^four formulations will
                                                                             X

 'accumulate in biological tissues.  The extent of bioconcentration _in Phase I

 tests could not be ascertained due -to -the insufficient sampling.  Consequently,

 the BCF values reported for the tested -formulations in Phase I  tests-must  be

 considered both preliminary and minimal values.

      Phase "IT chronic tests on 58% chlorinated, short chain-length n-paraffins

 indicate significant (P - 0.05) chronic adverse effects in the  range of 2.4 to

 20 ug/1 for rainbow trout, sheepshead minnow embryo-larvae, mussels, daphnids,

 mysid shrimp, and -the marine alga.  These effects generally include chronic

 lethality, altered growth, and reduced reproduction.  Shortcomings  identified

 in most of~the studies precluded identification of the lowest effect level

 concentration as well as the percent of the adverse effect*  Analysis of the

 .aquatic data indicate that adverse effects occurred at the lowest concentration
                                                                   S
... tested (0.5 ug/1) and that testing at lower levels may produce  additional

 significant adverse effects below 1 ug/1.

     B.  Toxicological Effects of 58% Chlorinated (€10-13 Vij-Paraf fins


      Tn the absence of surf icent toxicological data on other chloroparaffin

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                                        14
 formulations, all further discussion of the toxicolgical effects shall be
 limited^to the 58% chlorinated, short chain-length (010-13) n-paraffins
 tested in Phase II and whatever other environmental data are available on that
 formulation.
        . 1. Acute Toxicity
 .   „ Acute effect levels of chloroparaffins on some aquatic species must be
 interpreted with caution for some test species.  The water solubility of Cjj
 is only about 0.095 "to (U47 ppm, therefore -all toxicity values greater than
 that concentration are suspect,  for example, all 96-hour fish I/SO values are
 -greater than 100 ppm (Table 1).  Thus, -the absence of acute toxicity in some
 species is simply a function of too short a time period for the ma")) amount of
 chloroparaffm available in the water to penetrate the organism.  Further
 evidence that uptake rates are slow on some species is indicated by mortality
 and toxicological effects reported in both the Phase I .and Phase II tests on
 rainbow -trout and mussels.  Consequently,-the greatest concerns for this kind
 of chemical are usually .chronic effects.
      Table 1 contains what limited data are available .on the acute effects for
 short chain-length (Cio-13) chloroparaffin formulations.  Of these test species,
 the most acutely sensitive species to chloroparaff ins are daphnids and mysid
 shrimp which were both affected by the 58% chlorinated, short chain-length
 n-paraff ins at similar concentrations (the 96-hour-LC50 .values are 18 ug/1 and
 less than 14 ugA« respectively).  Other acutely sensitive aquatic invertebrate
 species included the oopepod Nitocra spinipes with a LC50 value of 100 ug/1,
 followed by the relatively insensitive chironcmid midge, greater than 162 ug/1.
      The two species of algae tested reacted very differently from each other
 when acutely exposed ±o 58% chlorinated short rhain-length jv-paraff ins.  The
/marine algae Skeletonema costaton was the--more sensitive species with a 96-hour
 EC50 of 42.3 (27.3 - 93.1) ug/1 for growth (cell oountK  The effect of the test

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                                        15


- material on growth rate of the marine algae was transient and  by Day 10 no


 difference in growth rates were apparent when compared to controls.  The highest  ,-._
                                             f

 reduction in growth .rate occurred during the first-two days and produced *" hr


 EC50 of 31.€ (20.7— 37.6) ug/1.  Toxicant effects on the .freshwater green


 algae* Selenastrurn capricomutum, differed f ran the marine algae in that its


 growth reduction was produced by higher test concentrations and the greatest   .  ..


 effect occurred at the end of the JO-day study. The  lowest reported EC50 for


-the green algae was 1,310 <880 —- 4,060)  ug/1 at 10 days,  which was derived by


 extrapolation from the 45 percent reduction found  at  the  highest test level,


"1,200 ug/1.  Increasing differences in growth rates compared to controls an the ,


 latter days of the study indicate that longer exposure would probably produce


 lower effect levels for green algae.  How much lower-is unknown.  Still another


 factor affecting the interpretation of these'Static test  results is the loss of


 50 to 80 percent of the residues from the water column.  Analyses of water and


 algae samples on Day 10 indicated that the balance of the residues had sorbed


 to the algal cells.  Increase in the number of algal  cells during the growth


 phase of this test has had the effect of distributing some residues to the new


 cells and thereby reducing the concentration per cell, whole  the longer-term


 toxicity in these tests might indicate toxic effects  m algal populations in


 flowing water, these toxicity values would underestimate  toxicity for algal


 populations in standing waters which would accumulate additional discharges,


 such as lakes, ponds, and estuaries.


      The rat LD50 value of greater than 21.5 g/kg  indicates minimal acute


 toxicity to mammals.  No acute oral LD50 or 1X30 data were available on birds.


         2. -Oircnic Toxicity


      Chronic effects were reported on all Phase i-«nd Phase II test species for


most chlorinated paraffin formulations tested (Appendix!)).  Chronic effects on


 sheepshead minnow larvae, rainbow trout, mussels,  daphnids, mysid shrimp, and

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                                         16

 marine algae indicated high sensitivity to chloroparaffins.  All of these  *

  species indicated effects at measured concentrations below 20 ug/1.  Due to
                                               *
 various testing inadequacies found  in each study, it Is impossible to determine

 the actual HATC level inmost studies.  Statistically significant (P=0.05)

 effects probably occur at concentrations even lower than those reported.  No

>. observable effect levels (NOEL) were not identified in the following studies:

 mysid shrimp (0.6 ug/1 -s- adult mortality), sheepshead minnow (2.4 ugA - body

 length), daphnids (2.7 ug/1— number of young and offspring/female), and

 rainbow trout (3.1 ug/1  - mortality).  Data indicate that chronic effects are

 more dependent on the duration of exposure than the test concentration for

 chloroparaf fins.  It would appear that  simply prolonging the exposure will

 elicit toxic effects, irrespective  of the test concentration.  For example,

 50 percent of the rainbow trout exposed to 3.1 ugA for 168 days in a fciocon-

 centration test began dying 64 days into the depuration period, while the

 same species exposed to  a slightly  higher test level (3.4 ugA) for the same

  time period  in a growth  study displayed no significant growth effects.  The

•* absence of growth effects is unusual, since it is considered one of the most

 sensitive, toxicological endpoints.

       Adverse effects reported for chloroparaffins include chronic mortality,

 significantly (P * 0.05) increased  and/or reduced growth, abnormal behavior,

 reduced filtration (feeding) activity,  reduced offspring per female, offspring

 survival,  reduced insect hatchability,  reduced insect emergence, and reduced

 cell growth  in algae.  The maximum  acceptable toxicant concentration (MAIC)

 levels for these effects were identified as < 2.4 ugA for the sheepshead

 minnow, <  2.7 ugA for daphnids, and <  3.2 ugA for rainbow trout.  At the

 lowest concentration tested {0.5 ugA)» mysid shrimp -mortality *ras 30 and 40

 -percent compared to 10 to 30 percent in controls and 25 and 30 percent in the
               in
 acetone controls. Whether and how much of the mysid mortality at the level of

-------
                                     • 17


0.5 ug/1 vas'-induced by the toxicant is difficult to tell.  The erratic mortal-

ity data may have resulted .from toxicity of other contaminates -in the food
                                              »

source.   The food source, Artemia, contained 0.6 ug/g chloroparaffins and

1.4 ug/g PCBs and organochlorine pesticides, mostly DDT.


     Chronic effects reported-in chloroparaffin studies submitted by the


Consortium are listed in Table 2 in order of increasing measured test concen-


trations.  Reproductive effects, other than growth, weretiot found .in either of

the ±wo .sheepshead minnow studies (2.4 to 54.6 ug/1 and 36.2 to 620.5 ug/1).

The two studies indicated a statistically significant IP « 0.05) increased


growth at low test concentrations (2.4 - 71.0 ug/1) and significant decreased

growth at the highest test level (620.5 ug/1),.  The pattern of growth enhance-

ment and growth reduction were repeated at similar test levels in rainbow


trout studies. 'The similarity between the growth curves for the two species

drawn from tJata in two separate tests on each of these species adds confidence


to the validity of this unusual dose-response curve.  No significant differences

in susceptibility were found between the various early life stages in rainbow

trout or sheepshead minnow.  Some differences in fish species sensitivity to

chloroparaffins were indicated toy the absence of or only slight sublethal

effects reported in bluegill and channel catfish studies.


     The absence of .reproductive effects found in the sheepshead minnow study

should be interpreted with caution.  First, Jthe exposure period for these two


studies were only 28 and 32 days long and adverse effects, especially.in fish,

are slow to manifest themselves, probably due to slow residue uptake.  Second/

these abbreviated reproduction studies began by introducing embryos to the test


concentrations, rather than exposing adults to the chemical for weeks prior to

spawning.  -It is generally-understood that embryos will not-sorb residues f ran

water readily, therefore, the developing embryos were TiotTnetabolicallyexposed


to toxicant concentrations-to the same degree that it would if -the female had

-------
                                        18


 deposited residues on the yolk.  Given the significant male mortality reported

 in the mysid chronic -study, it would appear that the differential mortality

 between the sexes resulted -when females deposited sane of their body burden of

 chloroparaffin residues into their eggs, a situation known  to occur in birds,

 fish, and other organisms with DDT.

    , Growth studies on cannon mussels exposed to the same short chain-length

 chloroparaffin indicated reduced growth rates at concentrations greater than

.2.3 ug/1 and less than 9.8 ug/1 (53 percent reduction in -both tissue and shell

 length).  Toxicant levels reducing mussel growth are less "than  the concentra-

 tions reported to reduce growth in sheepshead minnow (greater than 280 ug/1 and

 less than €20 ug/1) and in rainbow trout (greater -than 350  ug/1 and less than

 1,070 ug/1).

      Chronic effects on both crustaceans were found at similar  concentrations.

 The number of daphnid offspring per female was reduced by 44  percent at 277

 ug/l» the lowest test concentration. ~In mysid shrimp, a 33 percent reduction

 in offspring/female occurred at 7.3 ug/1.  Chironomid midges, another aquatic

 invertebrate, was not as sensitive as the above  two crustaceans, but adverse

 reproductive effects -on midge larvae were reported for hatching, emergence, and

 eggs per mass at concentrations of either "78 or  121 ug/1.

      Reproductive effects of 58% chlorinated, short chain-length n-paraffins on

 mallard -ducks included statistically significant effects on eggshell thickness

 and percent viable embryos per egg set at 1000 ppra.  The no observed effect

 level found in the avian reproductive test was 166 ppm.

         3. Bioconcentration
                                                                 s
      Long-term bioconcentration studies on mussels and rainbow  trout exposed to

 .58% chlorinated, short chain-length ji-paraffins demonstrated  high BCF levels in

 whole organists-ranging from 24,800 to 40,900 and 3,550  to 5,260, respectively.


"While the data for some organs were erratic and  never .stabilized, equilibrium

-------
                                       19



between water concentrations and whole organism residue levels were reached in



about 45 to 80 days in missels and about Day 90 in rainbow trout.  Depuration



'half-life rates for the whole organisms were reported as 9.2 to"19.8 days in



•the missel and 18.7 to 19.8 days in the rainbow trout.  Of the tissues measured



the highest residues occurred in the digestive organs of both species.  BCF



levels in the mussel's digestive gland/stomach ranged from 104,000 to 226,000.



In rainbow trout, initial residue levels were highest In the liver and viscera



with BCF values of 11,430 to 15,970, but the levels in the liver declined in



the latter half of the study to 2,770 to 3,930.  BCF values found in flesh or



carcass were considerably .lower (1,330 to 5,040).  Declining residues in trout



liver give the impression that the active elimination of -the C14 residues may



occur via-metabolic breakdown of the chloroparaffins.



     Itie bioconcentration study on mussels exposed to nominal concentrations of



2.35 and 10.1 ug/1 of 58% chlorinated short chain-length paraffins indicate BCF



values of 40,900 and 24,BOO, respectively for the whole animal.  Compared to



the gonad and residual tissues, the digestive gland had the highest residue



levels with BCF values of 104,000 and 226,400 at levels of 2.35 and 10.1 ug/1,



respectively.  Whole animal residues attained equilibrium at the  highest



exposure level at about Day 42, which also corresponded to the onset of low



level mortality that persisted throughout the 91-day exposure and through Day



125 (34 days into the depuration period).  As discussed earlier,  mortality



also occurred in the rainbow trout bioconcentration study during  the depuration



phase.  However the trout deaths began after 64 days of elimination and ceased



on Day 69, leaving only two surviving fish at the lowest test lever. Based on



a comparison of chloroparaffin uptake from water and food in the  literature,



the contamination of the fish food source at B.B5 to :2.2 ppm could not  be



considered responsible forrthe late mortality during'.the depuration phase.  T^e



BCF values reported in the two'bioconcentration studies agree well with results

-------
                                        20



 reported on -the sanre test material in the 60-day t.oxicity tests submitted on



 the mussel and rainbow trout (Table 3).  These levels, however, are consider-



 ably higher than x:hloroparaffin values previously reported in the literature.



 The BCF values are in^close agreement with'BCF levels Teported_foi? the same



 mussel species exposed to DDT (4,550-49,600) and fCB (7,200-26,600) by Geyer



 et al. (1982).



      Data in the two 10-day algal studies indicate low level accumulation of



 chloroparaffin residues directly front the water (Table 4K  The algal  residue



 data in Table 4 -indicate a general increase in the "BCF value as the test con-



 centration increases.  The -low BCF -estimates (£1  to 7.6) compared to BCF



 values for the same exposure period on mussels (10,099 - 11,915) and rainbow



 trout (1,500  -1,654), indicate that the uptake is probably passive sorbtion



 of the hydrophobic-residues to the cell wall rather than active transport.
                                     t


    -"Depuration rates for chloroparaffins in whole mussels and fish are slow.



 The half-life -for depuration in the whole organisms  were reported to be 9.2



 to 19.8 days  in the mussel and 18.7 to 19.8 days in  the rainbow trout.   f

                           =

        _4. Bicroagnification



      Estimation of BCF values resulting from dietary uptake of chloroparaffins



 was made from residues analyses results reported for Phase II studies.  The



 dietary SCF estimates for mussels and rainbow trout  are 0.46 and 1.5,  respec-



 tively.  Algae fed to the missels in the bioconcentration study contained 2.6



 ug/g wet weight.  The food pellets used during the latter part of the  rainbow



 trout study contained 0.85 ug/g short-intermediate chloroparaffins.  Residue



 contributions from these contaminated food to the  whole body residues  would



 account*for-11.8 to 13 percent in rainbow trout^-and  0.5 to 1.2 percent in "whole



-mussels.



      While one anight expect residues in food to compliment -residue uptake from



 water or sediments, their overall contribution to  whole body .residues As rela-

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                                        21
 lively small.  Test data reported in the literature by other researchers also
 indicate that chloroparaffin uptake fran water are greater than fran food
 sources.  The real significance of dietary uptake of chloroparaffin is a trans-
 port mechanism for exposure of organisms that -would not bioconcentrate residues
 directly fron water.
      C. Summary of Environmental Effects
      Acutely, the 58% chlorinated short chain-length 
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                                        22



 be exposure tine and concentration.  While the effect of -best-concentration  is



 an obvious factor, the effect of exposure duration, to the extent necessary  to



 show toxicity in the chlorinated paraffins, is highly unusual.  As -seen on the



 rainbow trout bioconoentration study,.168 days exposure and an  additional 64



 days t3f post-exposure depuration passed before significant mortality occurred.



 Very few chemicals demonstrate such prolonged development of chronic effects,



 and even fewer chemicals produce delayed mortality so late into the  depuration



 phase.  This delayed -mortality is reminiscent of toxic -effects  caused by the



 mobilization of stored T5DT/DDF residues during periods of stress, such as



 starvation, migration, reproduction, and residue concentration  in developing



- embryos.



      The ±wo sheepshead minnow studies are not adequate to test the  effects  of



-chloroparaffins on fish reproduction.  "First, the 28- and 32-day  studies were



 not of suffioent duration for chloroparaffin toxicity to manifest itself.



 Second, the exposure in -the fish reproduction studies began  with  embryos,



 thereby, failing to measure the effect of residues stored in egg  yolk.



      ^n ±he rainbow trout and mussel bioconoentration studies,  the BCF values



 were reported as 3,550— 5,250 and 24,800 — 40,900, respectively. These levels



 of bioconcentration are of considerable concern, especially  when  combined *tith



 persistence, -such as has been indicated for chloroparaffins. Distribution of



 chloroparaffin residues in .tissues appear to be similar for  species  as diverse



 as mussels, fish, quail, and mice.  Residue levels tend to be highest in those



 tissues with high cell turnover rates and/or a high metabolic capacity.  BCF



 values in mussels are similar to levels reported for DDT and PCB. Depuration



 half-life rates for chloroparaffins in whole mussels and fish are slow (9.2 .to



 19.8 days and 18.7 to 19.B days, respectively)^



      Uiomagnification of choroparaff irr irom food sources appears "to  contribute



 considerably less chloroparaffin to-tissues than bioconcentration from water.

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                                        23



 Biomagnification is of special concern because it provides a residue transport



 mechanism to organisms that would not otherwise bioconcentrate residues



 directly from water.   Biomagnification is also .sign ificant, because residues  -



 usually accumulate in those species at the top of .the food web, which have low



 reproductive capability.                                                 .,



      In general, one  might expect biomagnification effects to be greatest Jin



 species feeding on benthic organisms which are exposed to higher chloroparaffin



 concentrations in the sediments than are found in water column.  Consequently,



 chloroparaff in residues entering the aquatic environment, aught be expected to



•be found in most, if  not all organisms, especially those species at the top of



 the food web.



   ^  Insuf f ioent data are available, however,vto .correlate body residue levels



 with toxicolcgical effects.  While no data is  currently available to correlate



 hazard from tissue residue levels,-concern for bioraagn if action remains r>ecause



 residues may accumulate -in species at higher trophic  levels in the food web.



 Mortality data reported m missel and rainbow  trout Moconcentration studies



.Indicate that adverse effects do not necessarily cease when--exposure ends.



 Both species experienced mortality during the  depuration phase. .All, but two,



 rainbow trout died at the lowest concentration withm one week, 64 days into



 the depuration period.  Tbtal rainbow trout mortality occurred during the same



 time period at .the highest level.



      Chloroparaff in data indicate little toxic ity to  terrestrial species.



 Acute oral LD60  data  to rats of greater than 21.5 g/kg indicate low acute



 concerns for mammals.  Chronic effects on mammals  is  currently under review



 and can not be addressed at this time. -Chronic effects on avian reproduction



 Included statistically significant tP « 0.05)  effects on mallard eggshell



 thickness and percent viable embryos per egg set at 1000 ppm (NOEL 166 ppm),



      Ihe breadth of toxic effects in a wide variety of species from various

-------
                                        24
 environments in combination of high BCF values, slow depuration,  high toxicity,
 persistence,:and the widespread distribution of these chloroparaffin residues
 in ±he environment indicate that chlorinated paraffins pose a potential  threat
 to a wide variety of organisms, especially aquatic species.  Because this wide
 array of adverse effects occur in aquatic species at such low concentrations,
 at or below analytical detection limits, all chloroparaffin releases to  the
 environment are of considerable concern with .respect to fish and  wildlife
 safety.
*V.  ENVIRONMENTAL TUSK ASSESSMENT
   A. Scenarios
      The three environmental risk scenarios discussed below are based on the
 toxicological effects data identified in,laboratory studies, some limited field
 monitoring data at chloroparaffin manufacturing sites, and environmental
 residue concentrations predicted by Versar Inc. for three manufacturing/use  -  -
 sites selected by EPA to represent a variety of exposure parameters. The three
-sites include a large river, a small river/creek, and an estuary. A summary of
 the predicted environmental concentrations (PEC) in water, sediments, and baota
 at one or more locations at each of these sites are listed in Appendix A.
 Versar Inc. predicted environmental concentrations for both Chlorowax 500-C
 (Cio-12) and Chlorowax 70 (C20-3Q) *or ^^ controlled .and uncontrolled
 releases.  No assessment of Chlorowax 70 can be made at this time, because the
 environmental effects data needed to make a risk assessment .are only available
 for the shorter chain length compounds. .Therefore, the evaluation of adverse
 environmental effects on fish and wildlife will be limited to anticipated
 effects from the 58% chlorinated short chain-length (Cjn-12) ^-paraffins.
      This risk assessment is largely a comparison of predicted environmental
r concentrations in Appendix *-and the toxicological effects listed in Table 2.
 Chronic exposures are assumed at the predicted concentrations from .frequent or

-------
                                       25



 continuous releases.  It also assumed that interstitial water concentrations „ =



 are higher than water column concentrations, that residues sorbed to sediments



 are bioavailable, and that dissolved and total residues in water are at least



 partially, if not, ccnpletely available as exposure levels to organisms.



 Toxicological effects on the surrogate test species are extrapolated to local



 flora and fauna species and limited conclusions are made on the effect of



 species  interactions.  Jtesidue levels in various organisms-are estimated from



 data  in  Tables 3 and 4, using BCF values for the closest -test concentration.



 Interpretation of residue levels in whole animals is limited considerably,



 because  data correlating body residue levels to mortality and other effects



 are missing.



      1.  Schuykill River* Pennsylvania



      The predicted chloroparaffin residue levels in the Schuylkill River are



 presented in Table 5 for water, sediment and various trophic levels of ±>iota.



 While the predicted water concentrations of 0.26 and 0.5 ug/1 are too low to



 produce any acute toxicity according to available data, these water concentra-



 tions may i* expected to cause significant adverse chronic effects in .some of



 the more sensitive aquatic invertebrates and fish.  The lowest chloroparaffin



 test  concentration (0.6 ug/1) produced 30 and 40 percent mortality in mysid



 shrimp.  How much of that mortality is due to chloroparaf fin toxicity is hard



 to  distinguish from the 10 to 30 -percent mortality seen in controls and  the 25



 to  30 percent mortality in the acetone controls.  The test results from  other



 species  (rainbow trout, sheepshead minnow, and daphnids)  do not preclude



 adverse  effects at 0.5 ug/lr and possibly 0.26 ug/1.  No observable effect



 levels were below the lowest test levels for each .of these four species.



 Larval growth (length) in sheepshead oninnow was significantly affected at



 2.4 ug/1.  "The number of daphnid young were reduced 43.6 percent at 2.~7  ug/1.



Aid at 3.1 j?pb rainbow trout mortality was 50 percent.

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                                        26



      Adverse effects on mussels  at 2.3 ug/1  included a 7.7 percent reduction



  the tissue growth rate which was not considered statistically significant ^tP =



  0.05)  and mortality slightly Jugher  than controls  (7% versus 5%). ~3he effects



  of chloroparaffin residues in sediments at 440  ppb en -the sensitive life stages



  such as reproduction and larval  survival when setting on contaminated sediments



-  have not been studied and  are unknown for  mussels, clams, and other benthic



  organisms.  This  residue level is  considerably  higher than the 10 ug/1 concen-



• tration causing 33 percent mortality in the missel BCF study and the 9.3 ug/1



  causing more than 50 percent growth  reduction In the shell and tissue weight,



  A ccnplete life-rycle test on fish with longer  exposures, so that residues are



  present in  the  egg yolk, is also likely to cause significant adverse effects



  at lower test xxxicentrations in water.  However, additional-testing to identify



  no effect levels  or MATCs  may present a problem in measuring exposure concen-



  trations, because the limit of detection for chloroparaffins is about 1 ug/1.



      -Table  5 lists the predicted chloroparaffin residue levels in aquatic



  organisms  from  the Schuykill River.   Bioconcentration and biomagnification of



  chloroparaf fin residues from water-only exposure %«ould range fron 0.03 ug/g in



  water  column species to 30.7 ug/g  in predators  upon benthic species.  Maximum



  residue levels  in biota predicted  by Versar  Inc. was similar (33 ug/g).  These



  residue levels .are considerably  less than  the 166 ppn no effect level seen an



  the mallard reproduction study.  Consequently,  nor direct effects en avian



  reproduction are  anticipated from  chloroparaff in residues released at this



  site.  Population reductions may affect the availability of food for aquatic



  birds, especially wading birds which feed  en benthic species.    ^



    ,  Based  upon the BCF value  of 36,OOOX for rainbow trout, the chloroparaf fin



  levels -that bioconcentrated directly from  the water in planktonic and nektonic



  species, would  range~ from  0.94 - 1,8 ug/g. These ^species would include mostly



  planktonic unicellular and small colonial  algae and other non-swutming organ-

-------
                                        27
 isms, and nektonic species like daphnids and rotifers and filter-feeding fishes
 such as shiners, alewife, shad, and herring.  Biomagnification of "residues in
 nektonic primary carnivore's, such as bass and possibly brown trout, would
 contain residues-ranging from 1.4 to 2.7 ug/g (based on a 1.5-fold -accumulation
 factor derived from residues found in the rainbow trout controls in the BCF
 study).  Biese residue levels of 1.8 ug/g are, in fact, similar to the chloro-
 paraffin contamination levels present in -the food fed rainbow  trout in the BCF
 study.
      Bioccncentration of chloroparaffin in benthic organisms,  such as  aquatic
• insect larvae of chironomid midges, mayflies, and stoneflies,  clans, worms, and
 other benthic invertebrate filter feeders and detritus feeders, are estimated
 to be between 10,6 ^and 20.5 ug/g Abased on a BCF value of 40,900X for missels).
 Benthic carnivores* such as sunfishes, catfish, bullheads, goldfish, carp,
 minnows, and suckers, feeding on these benthic species would be expected to
 accumulate residue levels of 16.0 to 30.7 ug/g.
      Monitoring data from a manufacturing site on the Grand  River in Ohio,
                           s
 indicated some possibly adverse effects on aquatic insect larvae at similar
 chlorparaffin concentrations measured in the water at Site I tJownstream from
 the release point (Ramm, 1977).  Possible adverse effects were indicated by the
 authors in their observation that, "The abundance of insect  larvae, especially
 in the lower river, was relatively low compared to that in other similar rivers
 we have investigated.*  Verification of this reduction due to  chloroparaffin
 levels is not possible since no sediment toxicity data are available from
 which chronic toxicity to benthic organisms can be correlated  to chloroparaffin
 residue levels in the sediments.  Measured residue levels in sediments (3.1 —
 12.6 ppst) and benthic chironomid larvae ^nd worms (7.29 ppm) were about 10-fold
 higher than predicted for'that water concentration in Table  5.  Barely detect-
 able levels of chloroparaff ins found in some .fish tissues may  simply indicate

-------
                                        28



-±hat the sampled fish are recent immigrants and nest-long-term residents.  The



 absence of measurable residues in fish samples may have been due -to either



 chronic ±oxicity and/or reduction in food availability reported as reduced



 larval insect populations.



      Results from the available chronic studies are too erratic to wake any



 predictions on the interactions between species and between trophic levels.



 New chronic tests would be needed for daphnia, mysids, and a complete life



 cycle study on fish, -in order -to quantify the adverse effects of chloroparaffin



 residues at -the exposure levels predicted -for these uncontrolled releases.  :No



 adverse effects are anticipated on birds or avian reproduction from predicted



 .residues in biota at 33 ug/g.



      Predicted residue levels from controlled releases .(bottom of Table 5) in



 the Schuykill River are lower than any levels which might be expected to cause



 adverse chronic effects.



    •  Predicted chloroparaffin residue levels in -the Schuykill River from



 uncontrolled releases are sufficiently low that no acute toxicity  effects are



 anticipated on any aquatic species and 'these concentrations would  not form  a



 toxic barrier to migration of species through the area.  Predicted reside



 levels in the water approach the lower end of test levels producing adverse



 chronic effects in several test species, therefore adverse effects might -be



 expected in sensitive aquatic species.  Monitoring data-from the Grand River



 with chloroparaff in concentrations in sediments similar to predicted  levels in



 the Schuykill River indicated reduced larval insect populations.  Since labor-



 atory tests indicate that the insect larvae are not the most sensitive species



 to chloroparaff ins, population reductions may be anticipated on other benthic



 organisms.  Population reductions in these insect larvae and other important



 bentMc organisms might be -expected :to affect the availability of food for many



 aquatic species occupying higher trophic-levels, including important  sport

-------
                                        29



 fish species,-ducks, and wading birds such as herons.



     - 2. Sugar Creek, Ohio



      Chloroparaffin residue levels in Sugar Creek, Ohio exceeded adverse effect



 levels in the aquatic segments of the creek both above and below -the confluence



 with the Toscarawas River.  The mean stream flow rates in the two segments of



 the creek were 330 cfs in the first segment and 1740 cfs in the second segment



 below the confluence.  The predicted water concentrations of 0,4-to 4.1 ug/1



' are too low to produce any acute toxicity according to available data  and as



 such would not be expected to act as a toxic barrier to movement of aquatic



 organisms through the contaminated segments.



      Chronic effects, however, would be expected in some of the more sensitive



 aquatic invertebrates and fish from these residue concentrations in water in



 both segments of the river.  Below the confluence with the Tuscarawas  River



 the residue levels are" similar -to estimated concentrations in -the Schuykill



 River in Pennsylvania.  Since the fauna would be similar in the two areas,



 chronic effects similar to those predicted, for the Schuykill River would be



 expected.



      Since estimated Chloroparaffin residues in water (4.1 ug/1) in the segment



 above the confluence are clearly greater than measured test concentrations



 causing chronic effects -in several test species, adverse chronic effects would



 be expected on aquatic organisms. ~Ihe reported .adverse effects below  4.1 ug/1



 include mysid shrimp mortality and a 20.8 percent reduction in the -number of



 mysid young, 43.6 percent reduction in young daphnids and young daphnids per



 female, 50 percent mortality in rainbow trout,  and increased growth in both



 rainbow trout and sheepshead minnow.-  3he 4.1 ug/1 estimate also correlates



 well with the 3 ppm measured concentration at Site II, the discharge point from



 a manufacturing *site on the Grand River-anTfiio.  ^Adverse effects tioted "during



 the sampling period Included reduced larval insect populations, in fact, the

-------
                                         30



  only aquatic invertebrates sampled were a crayfish (normally a relatively



  insensitive species) and chironoraids.  Organisms in -the other sampling sites



  variously also'included clans, snails, tadpoles, and worms.



       Table 6 lists the estimated chloroparaff in residue levels in aquatic



  organisms from Sugar Creek.  Bioconcentration and bioroagnification of chloro-



  paraff in residues in the upper segment from water-only exposure would range



  from 7.56 - 14.8 ug/g in water column species to 128.6 - 251.5 ug/g in



  carnivores upon benthic species.  Maximum residue level in biota predicted by



  •\fersar Inc. vas similar (274 ug/g).  These residue levels are slightly higher



  than the 166 ppn no effect level seen in the mallard reproduction study,  but



- considerably less than than the chronic level of 1000 ppm causing eggshell



  thinning and embryo viability in mallard ducks.  Consequently, adverse chronic



  effects on avian reproduction might be possible from chloroparaffin residues



  released at this site -for fcirds feeding on predators upon benthic organisms



  and, possibly but not likely, for birds feeding directly on benthic species.



       Based upon the BCF for rainbow trout (36,OOOX), the chloroparaff in residue



  levels that bioconcentrated directly fron the water in planktonic and Jiektonic



  species, would range from 7.6 to 14.8 ug/g.  These species would include mostly



  planktonic unicellular and small colonial algae and other non-swimming organ-



  isms, and nektonic species such as small mobile crustaceans like daphnids and



  rotifers and filter-feeding fishes such as shiners, alewife,  shad,  and herring.



       Biomagnification of residues in nektonic primary carnivores, such as bass



  and possibly brown trout, would contain residues ranging from 11.3 to 22.1 ug/g.



  These residue levels are equal to or greater than residues levels measured in



  rainbow trout'BCF study when 50 to 100 percent mortality occurred during



  depuration.



       Bioconcentration of chloroparaffin in benthic organisms,  such -as aquatic



 ;-insect larvae of chironomid midges, mayflies, and  stoneflies,  clams,  worms, and

-------
                                          31
   other benthic invertebrate filter feeders and detritus feeders,  are estimated
   to be between 85.9 and.167.7. ug/g.  In fact, the residue levels  measured an
 .  chironcnud larvae at the discharge point *ere 93.4 ppro.  Benthic carnivores,
   such as sunfishes, 'catfish, bullheads, goldfish, carp,-rockbass, white bass,   .
   minnows, and suckers, feeding en these benthic species would be  expected to
   accumulate residue levels of 130 to 250 ug/g. ~The hardly detectable  residues
   in seme fish species of this trophic level cause one to question whether the
   sampled fish were residents or whether any resident  fish could survive chronic
   exposure.  All of the bioconcentraticn tests conducted en fish indicate  accumu-
   lation of chloroparaffins from either water or dietary exposures.
        Predicted chloroparaffin residue levels in Sugar Creek from uncontrolled
*.:„ releases are sufficiently .low that no acute toxicity effects are anticipated on
 -  any aquatic species and these concentrations vould not form a  toxic barrier to
   migration of species through the area.  Predicted residue levels an the  water
   exceed the lower end of test levels producing adverse chronic  effects in several
   test species, therefore adverse effects might also be expected in sensitive
  ,aquatic species =SUCK as fish, daphnids, and small crustaceans. .Monitoring data
   from a manufacturing site on the Grand River in Ohio, indicated  adverse  effects
   on some aquatic insect larvae at similar chlorparaffin concentrations measured
   in the water at Site II adjacent to the release point iRamm, 1977).   Population
   losses -in sensitive species will reduce the availability of food to aquatic
   species In higher trophic levels, including aquatic  birds such as ducks  and
   wading birds.  In addition, avian reproduction might be affected by feeding
   on aquatic organisms* since the chloroparaf fin residues in the food web  are
   predicted to be higher than the chronic no effect level.
        While insufficient 
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                                        32
 Results iron sediment toxicity tests would most likely also indicate adverse
 effects on reproduction and settling capability in freshwater clans and other
 benthic species.  Sediment toxicity results might also explain the-absence of
 -clams in the sampling' at Site II in the Grand River.
      Controlled releases into "Sugar Creek might be expected to cause chronic
 adverse effects on aquatic species.  While chloroparaff in levels -in ±he water
 column are not likely to impact'organisms, sediment levels of 130  ppb may
 reduce populations of benthic species and affect the availability  of food for
 *ll other aquatic species.
      3. " Houston Ship Channel/Galveston Bay,  Texas
      The Houston Ship Channel enters the northwestern part of Galveston Bay
 near the mouth of the'San Jacinto River (Figure 2).  The shipping  channel then
 turns south along sane islands that partially separate it from a series of
 interconnecting embayments to the east.  These bays from north to  south are
 Burnet, Scott, Tabbs, and the tipper San Jacinto Bays.  TitJal flow  and water
 circulation in these estuarine areas are such that while chloroparaffin
 residues are greatest in the channel itself*  the .residues are also spread into
 these highly productive, estuarine embayments.
      The U.S. Department of the Interior, Fish and Wildlife Service (1982) on
,±heir Gulf Coast ecological inventory maps Indicate that the Galveston .Bay area
 is a breeding and nursury area for many species of birds, fish, and aquatic
 invertebrates.  Many of these species are important either as a connercial
 fishery or as a sport fishery.  The Houston Ship Channel is a nursery area for
 such sport and ccramercially-important fish and Crustacea, as sheepshead, drum,
 southern flounder, white shrimps-brown shrimp, and blue crabs.' The adjacent
 San Jacinto Battleground Historic Park As inhabited by dabbling ducks,  red-
* -shouldered hawks, gulls,-terns,'herons, and egrets.
      Scott -Bay east -of ±he Houston Ship Channel is indicated as habitat for

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                                       33



 herons, egrets', roseate spoonbills, and olivaceous cormorants.  Tabbs Bay to



 the south is a nursery area  for white  and brown shrimp, blue crabs, and



 commercial -and/or sport fish species including drum, sheepshead, and southern



 flounder.                                                     -



     The shallow shore veas in the upper Calves ton Bay are a vast nursery for



 commercially-important white and brown shrinp, blue crabs, and ccnnercial and/



 or sport fish species: drum, sheepshead, and southern flounder.  The upper



 Calves ton Bay area ds -also a breeding  area for olivaceous cormorants, the



 white-faced ibis (an state endangered  species), gulls, terns, herons, egrets,



 and a breeding and nursery area for eastern oysters.  Other aquatic birds,



 like great blue herons, Louisiana herons, snowy egrets,-roseate spoonbills,



 and black skiimters, live and breed on the small islands and along the edge of



 the upper bay.



     Predicted chloroparaffin residue  levels in the Houston Ship Channel and



 the adjacent estuarine areas approach  or exceed the lower limits of -anticipated



 effect levels in -at least ten out of the eleven segments modeled by Versar Inc.



 
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                                        34



 no effect levels in the chronic tests.



      Table 7 lists predicted chloroparaffin residue levels in aquatic organisms



 in the Houston Ship Channel tthe first four segments), -adjacent embayments,  and



 Galveston Bay.  Bioconcentration and biomagnification of chloroparaffin from a



 water-only «q?osure are estimated to range fron fl.29 - 5 ug/g in plankton/hekton



 species to 4.9 - 85.9 ug/g ia first-level carnivores upon benthic species.



 Higher residue levels might be found in second-level carnivores and in other



 species near the top of the estuarine food web.  The maximum residue level in



 biota predicted by Versar Inc. was siinilar (100 ug/g).



      Based upon the bioconcentration factor (BCF) for rainbow trout~(36,OOQX)» -



 the chloroparaffin residue levels-that bioconcentrate directly from the water



 to planktcnic and nek tonic species, would range front 0.29 to 5.0 ug/g.  These



 species would include mostly planktonic unicellular and  small colonial algae,



 diatoms, copepods, small shrimp, a multitude x>f larval stages-of crustaceans,



 molluscs, polychaetesi fish, etc. that utilize water^currents to distribute



 their young, and filter feeding fish such as shad, silversides, menhaden,



 sardines, and-anchovies present in Galveston Bay system.  Biomagnification of
              ^


 these residues in first-level nektonic carnivores, such  as ^acks, would contain



 residues .ranging from 0.4 to 7.6 ug/g.



      Bioconcentration of chloroparaffin in benthic filter feeders, such as



 oysters, mussels, clams, and setae polycheate worms, are  estimated to be 3.3  to



 57.3 ug/g.  Bicmagnification of .residues from these benthic organisms  in



 predatory molluscs, sheepshead, drums, and stingrays, would range from 4.9 to



 85.9 ug/g.



      Biomagnification.of sediment residues in benthic fish such as mullet,



^pinfish, and catfish, and .benthic -invertebrates such as  detritus feeders,



 crabs, shrinp, im/sids, amphipods,' polychaete worms, whelks, and other  benthic



 invertebrates, are -estimated as t).2 to 2.0 ug/g.  Predators upon -these benthic

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                                       35



 organisms/ -such as seatrout, spot, croakersf  killifish,  and flounder, might be



 expected to contain 0.3 to 3.0 ug/g.



      Monitoring data collected at a manufacturing site on the edge of the



 Houston" Ship Channel {Figure 2) reported chloroparaffin  residues  in-sediments



 somewhat-higher-than the 1.3 ug/g predicted levels in the upper segment of the



 Houston Sup Channel (Raram, 1978).  The  residues at Stations H and I in the



 channel ranged from 1.5 to €.0 ppn, when corrected for poor analytical recovery.



 The highest residue level (50 ppm) occurred at Station D where the discharge



 from Patrick Bayou enters the shipping channel.  Oat  of  five water samples, the



 only sample found to contain chloroparaff ins was from Station F.



      A possible explanation for the lack of correlation  between residue levels



 in the water and sediment samples and "the location of the various sampling



 sites might ±>e flue to increased insolubility  of  chloroparaffin in saline water.



 Solubility levels of organic chemicals are typically  lower in saltwater than



-freshwater.   Station F, source of-the single ^jositive water sample, was located



 in a snail ditch near two outfalls from  the manufacturing site and as such



 probably discharges freshwater, thereby, being less saline compared ±o-the



 other stations located in Patrick Bayou  and the  shipping channel.   The measured



 level at Station F was 1.5 ppb, reported to be at the edge of the detection



 limit (1.0 ppb).  At "the other sampling  sites, residue levels in water .below



 the detection limit could have been due  to reduced solubility due the higher



 salinity.  Mo data are available that Indicate the difference in solubility



 between fresh and saltwater.



      Three out of the four stations having the highest chloroparaff in residues



 in sediments were located where water salinity were highest.   Station D which



 had the highest residue level, was located at the point  where salinity would



 increase dramatically-as the Bayou discharged  into the shipping channel.



 Stations P and T were located at the higher saline sites in the shipping channel.

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                                        36



 High residue levels ^t Station A, the fourth cite, could be attributed to poor



 flushing.  Station A was located upstream from two outfall points at the manu-



 facturing site.  Transport of chloroparaffin residues to this site would be



 dependent on incoming tidal tsurrents in the bayou -to the sampling site further-



 est up the bayou. "The residues would readily sorb to the organics, settle into



 the sediments, and persist, because flushing at that station would be.less than



 flushing at any sanpling site.



      Chloroparaffin residues were also measured in a few biological samples from



 five stations.'  The sanples included -whole crabs, killifish, and vegetation.



 The residue levels in the killifish and crabs ranged from 0.20— 0.42 ppn to



 0.10 to 0.52 ppm, respectively.  The highest residue levels were found in the



 xxabs collected at Station C, the station nearest Station D, which had the



 highest residue levels in sediments.-  Residue levels in crabs decreased as the



 distance of Stations B and J increased from station €„  Of Stations,B and C,



 the only sites at which fish were sampled, the highest chloroparaffin residue



 levels were found at Station B, the station nearest the two outfall points in



 Patrick Bayou.  No biological-samples were reported..from the four sampling



 -stations with the~highest sediment residue levels.  Although no prediction was



 made for residue levels in the Patrick Bayou from which to estimate residues in



•"biota, these residue .levels are about 10-fold below residue levels estimated



 for the shipping channel (2.0 ug/g).  As in the case of the Grand River, low



 residue levels in highly mobile species such as these crabs and killifish,



 probably indicate that these individuals were not long-term residents in the



 area.                                                             '



      The highest estimated chloroparaffin residue levels, i.e./those in carni-



 vores upon benthic species are slightly less than the 166 ppm no effect Jlevel



 seen in the mallard reproduction study.  Consequently, adverse chronic effects



 are unlikely on avian-reproduction, based on these residue estimates. However,

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                                        37
 given the fact -that predicted sediment values have been consistently lower than
 levels monitored at similar sites by Ramro (1977 and 1978), the model used by
 Versar Inc. -may be consistently underestimating releases and/or partition into
 sediments.'  These sediment predictions would also affect estimates of residues
:dn biota.
      In the absence of toxicity data correlating residue levels in sediments to
 toxic effects in benthic organisms, it is impossible to assess probable adverse
 effects on the nearly 200 benthic raacroinvertebrate gp^ctes listed in Galveston
 Bay by Shidler 0960).  Holland et al. U973) listed 32 benthic species at
 Station 22 alone in -the upper Galveston Bay.  Gillard (1974) delineated four
 characteristic henthic assemblages in the area of Tabbs Bay and upper Galveston
 Bay.              -     -                                   >
      Residue levels predicted in the Houston Ship Channel range from 1,300 ugAg
 (ppb) in the upper channel to 950 ug/kg in the lower channel.  "These levels-were
 less than the "1,500 to 6,000 ppb residues-measured in the upper ship channel.
 Residues levels in the upper enbayments and Galveston Bay ranged from  140 to
 ^40 ug Ag 
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                                       38
 resuspended' anto the water column on particles ty less  sensitive, benthic
 organisms like polychaetes turning over  sediments as they feed.
     The oyster is the most conroercially, and perhaps, ^ecologically-important
 benthic organisms to be -found in the Calves ton Bay system.  Commercially, the
 bay provides 50 to 90 percent of the entire Texas oyster  fishery.  Besides the
 areas open to the public,  658 acres are  privately leased  as of 1972, the last
 year for which data  was found.  Ecologically* the oyster  is Jmportant in the
 sedimentation of anorganic particulate matter from the  water column and the
 reduction of water-turbidity below the critical levels.  Water clarity affects
 the depth of light penetration into the  water and consequently, the amount of
-primary productivity (the  base of the food web), by phytoplankton, benthic
 algae, and seagrasses. /Turbidity also determines how deep-vegetation such-as
 seagrasses can-grow.  Oyster reefs and seagrass beds, which are both dependent
 on healthy oyster populations, provide the two most  important aquatic habitats
 in the bay. - The seagrass t>eds are -nursery areas -for many fish species like
 young sheepshead, seatrout,  southern flounder, red drum,  croaker, and kingfish,
 shrimp, and many other invertebrates.  Galveston Bay .has -the highest conmercial
 yields of any Texas  bay and  often leads  an production of  brown and white shrimp
 and blue crabs.  Galveston Bay has the-most heavy fishing pressure of any Texas
 bay system and the oyster  reefs are prime habitat for many sport fish such as
 adult  sheepshead, black and  red drums, and Atlantic croaker.  Oysters are also
 important for production of  pseudofeces  which provide the basis for additional
 food chains. .- Sediment toxicity tests are needed before the predicted residue
 levels in sediments  can be evaluated for adverse  effects on benthic species,
 including-oyster spat setting andjBurvival.
     Of the-349 avian species reported from the Galveston Bay area, .about 120
 plus aquatic avian species might be  expected to be directly exposed to chloro-
 paraffin residues in their food.  If chloroparaffins are  to affect any avian

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                                       39

species  in the Galveston Bay area, those-species roost-likely to be affected

would be benthic feeders such as the roseate -spoonbill, ibises (including the

state-endangered whiter-faced ibis), herons, egrets, "the federally-endangered

wood stork, bitterns, -rails, least curlew, icons sandpipers/ plovers, oyster-

catcher, ducks, grebes, and-mergansers.  Upper trophic-level, fish-eating bird

species, like the  federally-endangered brown pelican and bald eagle, the white

pelican, and osprey, might also be at risk. .Additional reproduction tests on

other avian test species may indicate If any of these, avian species might be

adversely affected by chloroparaffin releases into the Galveston TJay system.

Current  avian reproduction studies do not indicate a margin of safety for the

upper-trophic level birds in the Galveston Bay area based on the predicted

chloroparaffin levels in aquatic biota.                                    • ~

     Residue levels fron controlled releases into the Galveston Bay system have

been predicted to  range from 0.004 to .0,12 ug/1 in water, -from 10 to 100 ug/kg

in sediments, and  from 0.02 to 4.91 ug/g in biota.  These residues in water are

sufficiently low that even at the highest level 0.12 ug/1, chronic effects are
                          £
unknown  at this time.  The effect of the.residue .levels in sediments and biota

are  less certain.  Chloroparaffin.residues in rainbow trout measured during

the  depuration period were only 0.9 to 3;0 ug/g wet weight, when 50 percent

mortality occurred in the 3 ug/1 test level.  While it is possible that residue

levels in biota -may reach lethal levels in sate species and reduce seme popula-

tions under controlled releases, it is doubtful that chloroparaffin residues

would bioaccumulate sufficiently to directly affect avian reproduction.

     The potential for adverse effects in the Houston Ship Channel/Galveston

Bay  area frcm uncontrolled releases is great.  The bay is the most productive

bay  system an Texas for commercial oysters, shrimp, and blue crabs.  The oyster

reefs and seagrass beds are the-two most important aquatic habitats for young

and  adult fish, and both habitats are dependent on healthy oyster populations.

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                                       40

Galveston Bay has the heaviest fishing pressure of-any Texas bay system.  The

important sport fish include seatrout, sheepshead, drum, and southern flounder.

"Predicted chloroparaffin .concentrations in water-are sufficiently high that

chronic adverse effects may be anticipated in species such as fish,'zooplarikton,

shrimp,-mussels and oysters.  Population reductions in these species will alter

availability of food for many higher trophic-level species, including numerous

aquatic avian species nesting and feeding in the Galvestion Bay system.

     Population reductions in oysters would not only affect the commercial

value of the crop, but oyster losses over sane critical limit could alter water

quality in the bay. . Increased turbidity in the water due to oyster losses will

reduce primary productivity, the base of the food web, and reduce the amount of

areas on the bay where -seagrass beds can grow.  Deduction in oyster reefs and

seagrass beds would affect the two most important habitat areas in the bay for

young and adult sport fish, conmerically-important shrimp and blue crab.

    - Predicted chloroparaffin residues in "the sediments are sufficiently high

to  anticipate population reductions m sensitive benthic organisms.  Population

losses would affect availability of food to sane species higher in the food

web, including numerous aquatic bird species nesting and feeding in the bay.

unknown are the adverse effect levels of chloroparaffins in sediments on

recruitment ~and larval settling of benthic species. -Predicted residue levels

faioconcentrated and/or bioraagnif ied in biota exceed levels measured in rainbow

trout at a time when 50 percent of the remaining fish died. _The effect of
                                  *
these residue levels on survival or reproduction are unknown for many aquatic

species including fish.  Predicted residues from uncontrolled releases approach

-the no effect level for .avian species and leave no margin of safety.

    B.  Direct Effects

     1.  Acute "Itacicity

     Under the conditions described in the three scenarios, chloroparaffin

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                                       41



releases'are not likely to acutely affect any aquatic manuals, birds, fish, or



other aquatic species.~ Absence of acute toxicity in fish and mamnals appears



to be largely related to relatively low water solubility and low uptake rates.



Consequently, chloroparaffin releases predicted by Versar Inc., are not likely



to form a toxic barrier for migratory species through the contaminated area.



Based on the manmalian acute oral toxicity data and avian dietary levels in



the reproduction test, bioconcentration of chloroparaffin in biota will not



contain an acutely lethal dose.  While chloroparaffins are highly acutely toxic



to Crustacea, algae, and zooplankton species, it is doubtful they would pose



an acute -hazard to fish or wildlife.



  "  2.  Chronic Toxicity



     Chloroparaftin testing has indicated high chronic toxicity to several



test species.  Six out of the eight test species showed chronic effects below



20 ug/1.  No observed effect levels (NOEL's) were below test concentrations in



four of these test species, including the rainbow trout, sheepshead .minnow,



rnysid shrimp, and daphnids.  Higher mortality on males than females an the



mysid shrimp test suggested that males are more sensitive to chronic exposures



than females.  The cessation of mortality in the daphnid ±est after Day 6



suggests that the difference in mortality between sexes may be due to reduction



in body burdens via deposition 6f chloroparaffins into the yolk of their eggs.



Since male mysids -have no such pathway to dispose of chloroparaffin, residues



continued to increase until lethal levels were-reached.  Transfer of residues



to egg yolks has been confirmed by published data showing chloroparaffin



residues in seabird eggs.                                          s



     The reproductive effect of chloroparaffins residues deposited in eggs was



tested in chronic tests on daphnids,"mysid shrimp,-chironomids, and-mallard



ducks.  -Qratussion of stored residues in eggs in the sheepshead study started



with embryos raises concerns about adverse effects an early fish developmental

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                                        42



 stages,.  Also given the slow uptake -rate of chloroparaffins, the 26- to 32-day



 exposures were not of sufficient duration to measure the full extent of chronic



 toxicity.



      Chronic exposure ±o the chloroparaffin levels predicted_in the water and



-sediments -at the three scenarios is expected to reduce the species diversity in



 the receiving waters of all three sites.  Predicted concentrations in water



 either exceeded or approached the test concentrations that affected both fish



 species, mysid shrimp, and daphnids.   Additional  tests at lower concentrations



 are necessary ~to evaluate the level ~of effect for all four species.  Sorption



 of chloroparaff ins to sediments at 1,000 to 10,000 -tines the water level,



 suggest that sensitive benthic organisms are also likely to be effected.



 However, sediment toxicity data are not available ~to correlate residue levels



 in sediments with -toxic effects.



      Evidence" of population reductions in aquatic organisms was  reported in a



 monitoring study of -the Grand River that indicated insect larval populations



 lower than seen in similar Ohio rivers.  It is  unclear whether the paucity of



 biological samples and species at sampling sites  were coincidental with high



 residue levels measured in the sediments in the Grand River and Houston Ship



 Channel or indicative of areas depopulated by chloroparaffins.  Toxic effects



 front sediment residues could .be even greater than indicated.  Based on measured



-residues that were higher than predicted iniJoth  the Grand River and Houston



 Ship Channel, it-may be necessary to modify the model used by Versar Inc. to



 predict higher chloroparaff in residues in sediments.



      3.  Bioconcentration                                       *



   '  Data indicate that chloroparaff ins are Jbioconcentrated from water and are



 biomagnifled from one trophic level to another  in the food web/  Itesidue levels



 in biota exceed the no effect level in the avian  study and may pose a risk to



 avian reproduction in Sugar Creek area, and possibly the Houston Ship Channel/

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                                       43
Galveston Bay area.  "While predicted residue levels in the upper segment of
Sugar Creek exceeded the mallard reprcductaon *JOEL of 166 ppn, ±he residues are
-not close to the 1000 ppro effect level.  The importance of the Houston Ship
Channel and-Calveston Ttey to-a wide range of aquatic'birds and four endangered
species might require additional evaluation of data and reconsideration of all
assumptions.
      Except "for evaluation of risk to avian reproduction, insufficient toxicity
data  are available to correlate toxic effects -from either tissue residues or
dietary levels.  Fifty and one hundred percent mortality in the remaining
rainbow trout between Cay 64 and €9 of the depuration period at two test
concentrations, indicates that death may occur long after exposure from water
has ceased and even after a considerable loss of residues, v Jtesidue levels in
rainbow trout sanpled during that period of mortality were lower than residue
levels predicted in fish in all three scenarios.  Therefore, predicted residue
levels in fish and other might be expected to have adverse effects, including
death.
    C.  Indirect Effects
      1.  Short-term Effects
      Chloroparaffin releases predicted by Versar inc. are not expected to cause
any short-term indirect effects.
      2.  Long-term Effects
      indirect advei.se effects from Chloroparaff Ins may be from two general
sources, reduction in the availability of food to higher organisms and loss
of productive habitats.  The effect of reduced food availability are obvious
(reduced growth, lower reproductive potential, and possibly malnutrition and
death), but the effects from habitat loss are generally even more devastating.
    "The most devastating indirect effect that chloroparaffins could have is
probably the loss of oysters on Galveston Bay.  Oyster losses could result in

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                                       44



increased turbidity in water, reduced primary productivity in phytoplankton,



benthic algae, and seagrasses (basis of an extensive food chain in estuaries),



and losses in productive habitats-including the oyster-reefs and seagrasses



beds which are-nursery areas for many juvenile and adult fish, shrimp, and



blue crabs.  Without oysters filtering particulate natter out of the water



column below sane critical level, light penetration in the water would be



highly restricted and subsequently, the productive volume of bay would i>e



reduced by the -turbidity.  Population reduction in filter feeding species may



also affect water quality such that other species cannot survive.



     A second irerjor .indirect effect -from chloroparaffins would be reduction in



benthic faunal diversity as anaerobic conditions in the sediments increase.



the loss of sensitive burrowing benthic organisms from toxic-sediments reduces



the amount of sediment turnover and subsequent oxygenation of the sediments.



VJhen oxyen can -no longer diffuse readily into the pore water, the sediments



become anaerobic as organisms consume the limited amount of oxygen, die and



decompose, the anaerobic level slowly rises toward the surface of the sediments



driving out even the chemically non-sensitive species for lack of oxygen*  In



freshwater and estuaries, clams are important both as filter feeders and as



borrowers.  Predicted chloroparaf fin levels in sediments may be toxic to clams.



The absence of sampled clams at the Grand River site which had the highest



chloroparaf fin residue levels in sediments may be indicative of toxic effects.



ttule the effects of these two examples may be the most far-reaching, losses



of other populations can have unpredicted effects other than simply the loss of



that species from the ecosystem and/or food chain.                 '



     Disruption of the food web from the loss of chemically-sensitive species



and other species displaced by anaerobic sediments will affect many species in



both freshwater and estuaries.  Benthic organisms in the Galveston Ray area



form a large .portion of-the diet of many species of cuiiier daily-important

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                                         45

  fish,-as well as toenthic-fceding birds such as roseate spoonbills, and the      "v

  endangered white-faced  ibis and wood stork. -Reduction in fish populations from

  either loss of food or  chemical-sensitivity will affect other species of fish

  and fish-eating birds such as the osprey, herons, egrets, and-the-endangered

  bald eagle and brown pelican.

  VI,  CONCLUSIONS

     .  About 67 million pounds of chloroparaffins are manufactured per year for a

  wide array of uses.  Releases -from manufacture and uses are estimated .to be 50

  million pounds per year.  Chloroparaf fins are persistent in the environment and

  widespread contamination is indicated by monitoring in the united Kingdom and

  around two manufacturing sites in the U.S..  Chloroparaf fins are relatively

^ insoluble in water and  sorb readily to sediment at levels 1,000 to 10,000 tunes

- higher than overlying water.  Residues bioconcentrate at levels from 10,000 to

  40,000 in aquatic species and can also furhted Monagnify in the food web (1.5-

  fold) .  Chloroparaf fins have been measured in many benthic tirganisms and benthic

  fish species contain higher residue levels than the fish higher in the water
                           £
  column.  Residues have  been found in seabirds and their eggs; in terrestrial

  crops, and in human foodstuffs.

       Analysis of uncontrolled chloroparaf fin releases from manufacturing and

  use sites in three distinct aquatic areas, the Schuylu.ll River in Pennsylvania,

  Sugar Creek in Ohio, and the Houston ship Channel/fcalveston Bay area in Texas,

  indicate that chronic toxicity levels are approached or exceeded for several

  test species in all three environments.  Monitoring studies adjacent to the

  Houston Ship Channel and in the Grand River in Ohio indicate .that predicted

  residue levels in water, sediments, and benthic biota from releases are real is-

  tic, if not too low for sediments.

     " Predicted chloroparaf fin levels in all three scenarios are sufficient in

  water and sediments that chloroparaffins are expected to have adverse chronic

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                                       46
effects on a wide range of sensitive, local aquatic species.  Biological data
reported in the monitoring studies at two manufacturing sites suggested that
population reductions occurred in sane benthic species.  Oiironomid larvae were
reported to be less numerous than seen in other comparible rivers in the state.
KnS the absence of biological samples at -the ^our sampling stations in Patrick
Bayou and the Houston Ship Channel where the highest residue levels were found
in sediments could be either a coincidence or. indicative that benthic species
%iere not present.  The monitoring study reported only residue levels and gave
no details about biological sampling.  Measured residues in the highly motile
species at levels lower -than predicted compared to chironomid data, suggest
that the motile species were not permanent -residents.
     Absence of chronic no observed effect~levels 4NOEL) in four-test species
(rainbow trout, sheepshead minnow, daphnia, and mysid shrimp) at concentrations
close to predicted environmental levels suggest that chronic effects will occur
In-each scenario.  Much higher residue levels in the sediments suggest that
chronic effects -will also occur in benthic species.  The level of these adverse
effects are unknown due to poor -test results an the studies and the absence of
sediment toxicity tests.  Comparison of chronic toxicity levels of chironomid
larvae with other test species, suggest that, if the less sensitive, chironomid
population was reduced by these residue levels in sediment, than all other more
sensitive benthic populations would also be affected.  Oysters and clams are
two sensitive benthic organisms which can affect the aquatic environment well
beyond simple reduction in food availability like many species.  Populations
reductions in oysters could reduce water quality, inhibit primary production
by phytoplankton fthe base of food web), and destroy the two most productive
habitats in Galveston Bay estuary. ± Population reductions-in sediment-burrowing
species .like clans affect sediment porosity and dissolved oxygen penetration
into sediments, which causes sediments to become anaerobic and uninhabitable

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                                       • 47



 for most benthic infauna.- flenthic population reductions would affect food



 availability for a wide array of aquatic species  including wading birds like



 .the roseate spoonbill, and the endangered white-faced ibis and wood stork, and



 fish-eating  birds like the herons, -egrets, osprey, and endangered .bald eagle



 and brown pelican in the Galveston Bay area.  Predicted residues in Sugar Creek



 %»ere sufficiently high to exceed the NOEL for avian reproduction. - Widespread



. utilization of the Galveston Bay area by aquatic t»irds also •warrants close



- scrutiny for possible Atoxic effects.  Predicted chloroparaff in levels in the



 biota of Galveston Bay indicate no margin of safety for aquatic birds.  No



 adverse effects are anticipated In migratory species (fish, -birds, or inverte-



 brates) which traverse any of the three release sites.



      While insufficient data are -available front existing tests to quantify



 chloroparaff in effects on fish reproduction, sediment toxicity to benthic



. species or toxic effects on settling of planktonic larvae of benthic species,



 monitoring data indicate that predicted residue levels will adversely affect



 aquatic species in all three scenarios.  Although predicted chloroparaffin



 levels may be highest in Sugar Greek, the complexity, sensitivity, and produc-



 tivity of the Galveston Bay area make it the most ecologically and economical ly-



 -Jmportant of the three scenarios.  Chloroparaff in levels measured in rainbow



 trout when 50 percent mortality occurred during the depuration period, indicate



 that adverse effects can ~be anticipated from predicted residue levels in biota



 •at-three sites.  Any correlation between internal residue levels and their



 effects are uncertain, isecause the mechanism(s) of chloroparaffin toxicity and



 metabolically-active site of concern is unknown.                 ,,



      In the absence of predicted environmental releases and residue levels, no



 effort has been made here to evaluate the .risk posed by the disposal of chloro-



 -paraffms.  Monitoring data in United Kingdom indicate that^flhile chlorinated



 Tj-paraffin residues are usually highest near manufacturing sites, residues

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                                       48



were found at remote sampling sites.  'The source of these remote residues are



thought to have occurred from disposal.  Chronic exposure to these levels



would be expected to adversely affect sensitive species.  However, the absence



of measurable residues an the study does not mean adverse chronic effects will



not occur, because the limit of detection in water is too high to adequately



monitor either test concentrations or environmental samples.

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                                       49

VII.   REFERENCES

Campbell, I. and G. McConnell. 1980.  Chlorinated paraffins in the environment.
     1. Environmental occurrence.  .Environ. Sci. Technol. 14(10)1209-1214.

Federal Register.  TSCA. Jnteragengy Testing Committee: Initial report to the
     Administrator, Environmental Protection Agency.  Itederal Register 42(197):
    , 55026-55080, October 12, 1977.

Federal Register.  [OPTS 42004; TSH-FRL-1988-7] Chlorinated paraffins; response
     to the Interagency Testing Connittee.  Federal Register 47(5):1017-1019,
     January 6, 1982.

Gillard, R. M. 1974. Distribution, abundance and species diversity of macro-
     benthic and meiobenthic invertebrates in relation to Houston Ship Channel
     pollution in upper Galveston Ray and lahbs Bay, Texas.  Ph.D. Dissertation,
     Texas A&M University.  186 p.

Geyer, H., P. Sheehan, D. Kotzias, 15. Freitag, and F. Korte. 1982. Prediction
     of ecotoxicological behaviour of chemicals: Relationship between physico-
     chemical properties and bioaccunulation of organic chemicals in the nussel
     Mytilus edulis.  Chenosphere 11(11)^1121-1134.

Harland, B. J., 5. K. Cornish, and R. I. Cunning.  Chlorinated paraffins Phase
     II studies: Determination of background contaminants in organisms, fish
     food and dilution waters.  BL/B/2307. Brixham Laboratory, Imperial Chemical
     Industries PLC.  September 1983.

Hildebrecht, C. O. - Biodegradability study on chlorinated waxes."  Lab. Hep.  No.
     50-0405-001. Environlab, Inc., Plainsville, Ohio.  1972.

Holland, J. S., N. J. Maciolek, and C. H. pppenheimer. 1973.  Galveston Bay
     benthic community structure as an indicator of water quality.  Contrib.
     Mar. rfici. 17:169-188.

Howard, P. H., J. Santodonato, and J; Saxena.  Investigation of selected
     potential environmental contaminants: Chlorinated paraffins.  Final Report.
     Contract No. 68-01-3101, Project No. Li259-05. "Prepared for Office of
     Toxic Substances, U.S.  Environmental Protection Agency, Washington, D.C.,
     November 1975. .EPA-560/2-75-007, .109 p.

Linden, E., B.-E. Bengtsson, O. Evanberg, and G. Sundstrom.  1979.  The acute
     toxicity of 78 chemicals and pesticide formulations against two brackish
     water organisms, the bleak (Alburnus alburnus) and the harpacticoid
     Nitccra spinipes.  Chemosphere 8(11/12):843-851.

Long, J. W.  Existing chemical market review on chlorinated paraffins.
     Economics and Technology Division, Office of Toxic Substances, U.S.
     Environmental Protection Agency, Washington, D.C.,  July 1984.

PEI Associates, Inc.  Exposure assessment of chlorinated paraffins.  Contract
   ..No. 68-02-3935, Work Assignment No. 42, PN 3607-26.  Prepared for Office
     of Pesticides and Toxic Substances, U.S.  Environmental Protection Agency,
     Washington, D.C.,  December 21, 1984.

-------
                                       30

Rabert, «W. S. "."Hazard assessment for chlorinated n-paraff ins: Effects on
     fish and wildlife.  Environmental Effects Branch, Health and Environmental
     Review Division, Office of Toxic Substances, U.S. Environmental "Protection
     Agency, Washington, B.C.,  January 1985.

Ramon, A, E.  An investigation of chlorowax in the lower Grand River. Final
     Report.  Submitted to Diamond Shamrock Corporation. "-Prepared-by Environ-
     mental Resource Associates, Inc., JJetter dated August 15, 1977.

Ramro, A. E.  Final report to Mr. Jack Borror, Diamond shamrock Corporation,
     concerning the analytical results of chlorowax determinations made  on
     samples collected in Houston, Texas, between August 8—12,  1977.  Environ-
     mental Resource Associates, Inc., Letter dated November 21,  1978.

Shidler, J. 1960.  Preliminary survey of invertebrate species. Texas Parks and
     Wildlife Department. Job Rep. No. MO-l-R-2.  15 p.

Tarkpea, M., E. Linden, B.-E. Bengtsson, A. Larsson, and 0. Svanberg. 1981.
     Products control studies at the Brackish Water Toxicology laboratory 1979-
     1980.  Swedish Environmental Protection Board, Brackish Water Toxicology
     Laboratory, Nykoping. Report NBL 111 (in Swedish), p. 45. "In;  Svanberg,
     O. (ed.). Chlorinated paraffins: A review of. environmental behaviour and
     effects.  Swedish Environmental Protection Board, Report SNV PM 1614.

U.S. Department of the Interior. 1982.  Gulf Coast ecological inventory.  U.S.
     Dept. Int., Fish Wildl. Serv.,
                                                                 * j       .,

Versar Inc.  Prelminary "Exposure Assessment for chlorinated paraffins: Final
     report.  EPA Contract No. 68-02-3969, Task No. 46.  Prepared for Exposure
     Evaluation Division, Office of Toxic Substances, U.S.  Environmental
     Protection Agency, Washington, D.C.,  August 5, 1985.

Wolfe, L. *,., W. M. Pulich, and J. A. Tucker. 1974.  Checklist of the birds of
     Texas.  Texas Ornithological Society.  128 p.

Zapotosky, J. E., P. C. Brennan, and P. A. Benioff.  Environmental fate  and
     ecological effects of chlorinated paraffins.  Argonne National Laboratory,
     Div. Environ. Impact Studies.  Prepared for Environmental Assessment
     Branch, Office of Toxic Substances, U.S.  Environmental Protection Agency,
     Washington, D. C. ,  April 1981.

Zitko, ~V. and E. Arsenault.  tSilonnated paraffins: Properties, uses, and
     polution potential.  Fish. Mar. Res. Dev., Tech. Rep. 491.  38 p. 1974.

Zitko, V. and E. Arsenault.  Fate of high-molecular weight chlorinated paraffins
     in the aquatic environment.  169th Nat. Meet. Aner. Chen. Soc., April 6-11,
     1975.                                   -                    "

-------
 Table 1.  Acute environmental LC50 values for short (Cio-13> chain-length
           chloroparaffins (58% chlorination unless indicated otherwise)
Test Species
Fish:
Bluegill Sunfish
(Lepomis macrochirus)
Channel Catfish
(Ictalurus punctatus)
Tathead Minnow ~
(Pimephales promelas)
Rainbow trout
(Salmo gairdneri)
Bleaks
(Alburnus alburnus)
Witaclor 49 49% Cl
Witaclor 55EN 56% Cl
Witaclor 63 €3% Cl
Chlorparaffin
Huls 70C 70% Cl
Witaclor 71P 71% Cl
Aquatic Invertebrates:
Waterflea
(Daphnia magna)
Duration
(hours)

- 96

- 96

-96

96



96
96
96

96
,96

48
96
Test Concentration
(mg/l)

> 300

> 300

> 100

> 300



> 5,000
>. 10,000
> 5,000

> 10,000
> 5,000

0.046 *
0.018
"Reference **
_ ~
Johnson and Pinley (1980)

Johnson and Finley (1980)

Johnson and Finley (1980)

Johnson and Finley (1980)
-


Linden et al, (1979)
Linden et al. (1979)
Linden et al. (1979)

Linden et al. (1979)
Linden et al. (1979)

Chloroparaffin Consortium
Chloroparaff in Consortium
 Mysid Shrutp            96
 (Mysidopsis  bahia)

 Copepod
 (Nitocra spinipes)
 Witaclor 49     49% Cl   96
'Cereclor 50LV  49% Cl   96
 Cereclor 70L   701jCl   96
 Chlorparaffin
  huls  70C      70% Cl   96

 Midge larvae            48
 (Chironanus  tentans)

 Algae;
 Marine  Diatom           48
 (Skeletonema costaturn)   -96

 Freshwater Green Alga    ' 96
 (Selenastrum          * 168
 capricornutum) "         240
 <  0.0141 *     Chloroparaffur Consortium
   0.06      - - Tarkpea et al. (1981)
   0.10         Tarkpea et al. (1981)
<  0.3          .Tarkpea et al. (1981)

-<  5            Tarkpea et al. (1981)

>  0.162        Chloroparaffin Consortium
  0.0316       Chloroparaffin Consortium
  0.0423       Chloroparaffin Consortium

  3.69       " Chloroparaffin Consortium
  1.55         Chloroparaf fin .Consortium
  -1.310     .   Chloroparaffin Consortium
  *  Revised value based on best  estunate from raw data.
"**  Citations may be found In the Hazard Assessment Document

-------
Table 2.  Chronic environmental toxicological effects in order of increasing
          •test concentrations.
                                             *

Test Level  -   Test Species                 "lexicological Effect
   (ug/1)	

    0.6       Mysid Shrimp          35   %  adult mortality (controls 20-27.5%)
              (Chronic - 28 days)

    1.2       Mysid shrimp       t  45   %  adult mortality (controls 20-27.5%)
              (Chronic - 28 days)   14.7 %  reduction in nunber of young

    2.1       Daphnia magna                 no effect
              (Semi-static - 14 days)*

   "2.3       Common Mussels         2.6 %  increase in growth rate of shell
              (Growth - 84 days)     7.7 %  reduction in growth rate of tissue
                                            (dry weight)

    2.35      Ccmnon Mussel          7   %  mortality (5 % control mortality)
              (BCF - 147 + 98 days)

 ,  2.4       -Mysid Shrurp       *  42.5%  adult mortality (controls 20-27.5%)
              (Chronic - 28 days)    2.0 %  reduction in number of young

    2.4       Sheepshead Minnow      3.8 %  increase in body weight
              Study 1-28 days) *   4." °  increase in body length

    2.7       Daphnia magna      *  43.6 %  reduction in number of offspring
              (Chronic - 21 days)t  43.9 %  reduction in offspring/female

  „  3.1       teinbow Trout      *  50.0 %  mortality
            - XBCF - 168 +
               €4-69 days)

    3.4       Rainbow Trout          0.02%  increase in body weight
              (Growth - 168 days)    0.7 %  increase in body length

    3.5       Daphnia magna                 NOEL
              (Semi-static - 14 days)

    3.8       Mysid Shrimp          32.5 %  adult mortality (controls 20-27.5%)
              (Chronic - 28 days)   20.8 %  reduction in number of young

    4.1       Sheepshead Minnow  *  14.9 %  increase in body weight
              (Study 1 - 28 days)*   3.7 %  increase in body length

   -4.5       Marine Diatom          0.9 %  increase in cell density
              Skeletonema costatum   0.8 %  increase in growth rate
              (Acute - 2 days)

    5.0     "  "Daphnia magna         16.4 %  reduction in number of offspring
              (Chronic - 21 daysl   13,0 %  reduction in offspring/female
                                     9.9 %  mortality in offspring

-------
Table 2.  (cant.).

Test Level      lest Species                 "Tbxicological Effect
                (Study - Exposure)
    5.0  -^    Mysid Shrimp      ,   "20   %  mortality
        -.- -  (Acute - 4 days)

    6.2       Daphnia magna          6.9 %  reduction in young/female
              (Semi-static - 14 days)

    6.4       Sheepshead Minnow  *  31.3 %  increase in body weight
              (Study 1-26 days)1*   3.5 %  Increase in body length

    6/7       Skeletonema costatum   5   % - reduction in growth rate
              (Acute — 2 days)       2.4 %  Increase in cell density

    7.1       Mysid Shrimp                  no mortality
              (Acute - 4 days)

    7.3       Mysid Shrimp          30   %  adult mortality (controls 20-27,5%)
             -.(Chronic — 28 days)   27.4 -§  reduction in number of young
           ^ '   .        *         ' *  32.6 %  reduction an offspring/female

    8.9       Daphnia magna      *  36.6 %  mortality
              (Chronic - 21 days)   66.1 %  reduction an number of offspring
                                 *  49.9 % .reduction an offspring/female

    .9.3       Ccranon Mussel     ~ *  52.fi %  reduction in growth rate of shell
              (Growth - 84 days) "*  53 .R %  reduction in growth rate of tissue
                                            (dry weight)
•>
              "Daphnia magna    r  ~*  50.0 %  adult mortality
              (Semi-static -        78.9 %  reduction in number of offspring
              14 days)        -  t  59.8 %  reduction in offspring/female
                            •t t- 29 — 57   %  increase in the number of days to
                                            first release of young from brood

   10.1       Common Mussel      "*  33   % -mortality (5 % control mortality)
              (BCF— 91 + 84 days)

   12         Daphnia magna      *  50.0 %  mortality
              (Chronic - 21 days)

   12.1       Skeletonema costatum  12   %  reduction in growth rate
              (Acute - 2 days)   f  14.3 %  reduction in cell density

   13         Cannon Mussel  "   t          occasional reduction -in foltration
              (Phase 1-60 days)          -activity

   13.7       Mysid shrimp       *  50   %  mortality
              (Acute - 4 days)

-------
Table 2.  (cont.l.
 Measured
Test Level
   (ug/1)
             Test Species
             (Study - Exposure)
                                             Toxicological Effect
J4-3      -Bainbow Trout
           ~(BCF - 168 +
            64-69 days)
                                   100   % mortality in remaining population
14,9
16.3
17.2
19.6
22.1
23.8
24.0
31.6
Mysid Shrimp * 40 ^
(Acute - 4 days)
Daphnia magna ' * 100 ?
.. (Chronic - 21 days)
, Tteinbow trout * .25.4 *
(Growth- 168 days) 6.2 *
Skeletonema costatum* 30.0 S
(2 days) * 44 *
Sheepshead Minnow '* .27.5 *
(Study 1-28 days)* 7.2 *
Mysid Shrimp " * 95 3
(Acute - 4 days)
Mysid Shrimp . * 100 1
(Acute - 4 days)
Marine Diatom" * 50 <
Skeletonema costatum
i mortality
t mortality
\ increase in body weight
t increase in body length
t reduction in cell density
t reduction in growth rate
t increase in body weight
t increase in body length
i mortality
i mortality
i reduction in growth (cell count)
           (2 days)

33         Hainbow Trout      -t  33.3
           (Phase I - €0 days)t  37.9
                              t  34.2

36.2       Sheepshead Minnow *  21.3
           (Study 2 --32 days)*   7.4

43.1       Marine Diatom      *  47
           Skeletonema costatum* 34.2
           (2 days)

44         Common Mussel      t
           (Phase I - 60 days)-  ~    .

54.8       Sheepshead Minnow  * :"31.°7
           4Study 1-28 days)*   6.4

€1        * Midge - larvae      ;" 19.3
           (Chirononus -tentans)   6^1
           (Chronic - 49 days)
                                         %  mortality
                                         %  -increase in body weight
                                         %  increase in -body length

                                         %  increase in body weight
                                         %  increase in body length

                                         %  reduction in rate growth
                                         %  reduction in cell density
                                           occasional reduction in filtration
                                           ^activity

                                         %  increase  in body weight
                                         %  increase  in body length

                                         -  21.7  %  reduction in emergence
                                        —  9.4  %  reduction in filial eggs/
                                                  egg mass

-------
Table 2.   (cent.).

Test Level     Test Species                  Ibxicological Effect
    (ug/1)	(Study - Exposure)	

   71.0       Sieepshead Minnow  "*  15.1 %  increase in body weight
              (Study 2—32 days)*   5.6 %  increase in body length

   71         Common Mussel      t  50.0 %  mortality
              (Phase 1-60 days)

   78         Midge - larvae     *  60.0 *  reduction in parent egg hatch
              (Chironomus tentans)  16.9 %  reduction in emergence
              (Chronic — 49 days)   10.5 %  reduction in filial eggs/egg mass

:  100         Sainbow Trout    -~t.  13.3 %  mortality
              (Phase 1—60 days)t  13.5 %  ancreaso in body weight
                                 ~t   €.7 %  increase in body length

  100         Copepod              "50   %  mortality
           _  Nitocra spinipes
              (4 days)

  110         Green Algae           16   %  reduction in cell density
              (Selenastrum
               capncornatum)
              (Acute - 3 days)

  121         Midge - larvae     * 100   %  reduction in emergence
              (Chironomus tentans)
              (Chronic - 49 days)

  130         Demon Mussel      X  96   %  mortality
              (Phase I - ^a days)

  161.8       Sheepshead Minnow     13.0 %  increase in body weight
              (Study 2 - 32-days)*  -3.4 %  increase in body length

 - 162         Midge — larvae     ~* _100  - % - reduction on emergence
              (Chironomus tentans)
              (Acute - 2 days)

  220      '   Green Algae     ""  *  23   %  reduction in cell density
              (Acute - 3 days)

  279.7       Sheepshead Minnow      1.9 %  increase in body weight
              (Study 2—32 days)    1.9 %  increase in body length

  350         Rainbow Trout     " t  58.6 % /mortality
              (Phase I - 60-days)   - 3.1 \  decrease in body weight
                                    - JL.9 %  decrease in body-length

  390       -  Green Algae        *  J.8  - % -reduction in cell density
              ..(Acute — 4 days)

-------
Table 2.  (cent.).
 Measured
Test Level
   
-------
Table 3*  Bioconcentration data in order of increasing exposure concentrations
          ty species
Test Level  "   Test Species
  (ppb)	(Study - Exposure)
BCF Value     "  Residue Levels (range)
                     (pern)
Mussel
.2.35
10.1
13
,-44
71
130
Fish
3.1
14.3
.33
100
350
1,070
3,050
•o. JIIBIL i_ L •_• LI i « 1 m rtrtf\ " "i "^^ t ^i* ^ o^ \
UUtiiuun Mussel 40,900 . . 122 (7o-lB7j
{BCF - 147 days)
Cannon Mussel "24,800 ~ 249 (144-365)
(BCF - 91 days)
Cannon Mussel 25,292 329
(Phase 1-60 days)
Cannon Mussel * 16,427 723
(Phase 1-60 days)
Cannon Mussel 5,785 411
(Phase 1-60 days)
Cannon Mussel '12,177 1,583
(Phase 1-60 days)

Rainbow Trout 3,600 JJ.O (8.3-15.6)
. (BCF - 168 days
Rainbow Trout ' 3,300 75.2 (62.6-87.3)
(BCF— 168 days)
Rainbow -trout "7,155 "236
(Phase 1-60 days)
Rainbow trout ' 7,816 782
(Phase 1-60 days)
Rainbow trout 3,723 1,303
' (Phase 1-60 days)
.Rainbow trout .2,642 .2,827
(Phase 1-60 days)
Rainbow trout - 1*173 3,577
              (Phase 1-60 days)

-------
Table 4.  Comparison of 10-day bioconoentration estimates for four aquatic
          species
   ~3test "Species
Test Level*   ~B£F Value    Residue Level-
istuoy — Exposure; IPPDJ (Km;
Marine Diatom
Skeletonema costatum
(Acute - 10 days)



-
Freshwater Green Alga
Selenastrum capncomutum
(Acute - 10 days)




Common Mussel
(Mytilus edulis)
(BCF- 10 day est.)
Rainbow Trout
(Salmo gairdneri )
(BCF - 7 and 10 days)
1,4

2.5
6.6
6.8
12.1
^17.8
35

:*2
79
100
150
140
2.35

10.1
3.1

14.3
£_1.1 < 0.0016
~~
< 1 - < 0.0025
- - 2.4 0.0224
5.5 . O.0372
4.0 0.0479
3.5 0.0622
1.5 . 0.051

1.9 0.118
3.2 0.251
4.1 0.410
-4.7 07710
7.6 1.060
ril,915- . -28 (24-32)
-
10r099 102 (87-117)
1,500 . 4.65 (3.4-5.9)

1,654 '23.65(19.2-28.1)
* -Water concentrations used -to conpute the BCF value in  algae were measured
 - -concentrations on Day 10 (the same day residues in -the algae were measured)

-------
Table 5.  Chlorpparaf f in residue levels (ug/g) in ±>iota due to bioconcentration
          and biomagnification in the Schuykill River near Conchohocken, Pa.


  Source of          Bioconcentration (BCF)    "     Biomagnification
- Exposure           Plankton    Filter             U.5X BCF or PEC)
                     & Nekton    Feeders     Detritus  First-level- "Benthic
	(3,600X)   (40,900X)    Feeders   Planktivores Carnivores

Hater

 Dissolved Cug/1)

    0.26               0.94        10.«               -         1«4       16.0
 Total (ug/1)

    0.50
 1.8
20.5
2.7
30.7
Sediment  1ugAg)

  440              1,600*
         18,000*
                 0.66
Controlled Releases

Water

 Dissolved (ug/1)

    0.009
 0.003
.0.04
0.005
  0.06
 Ttotal (ug/1)

    0.02
 0.07
 0.82
0.11
 1.2
Sediment (ugAg)

   20
72*
                 0.03
*  No known biological component for residue level.

-------
Table 6.  Oiloroparaffm residue levels (ug/g) in biota due to bioconcentration
         - and biomagnification in Sugar Creek near Dover, Ohio
  Source of
  Exposure
Bioconcentration (BCF)
Plankton    Filter
& Nekton    Feeders
(3t600X)   (40,900X)
       Bicroagnification
       (1.5X BCF or TEC)
Detritus  First-level "   Benthic
Feeders   Planktivores  Carnivores
Uncontrolled Releases

Water
 Dissolved (ug/1)
2.1
Total (ug/g)
4.1
0.7
Sediment (ugAg)
3,600 _13
600 2
Controlled Releases
Water
Dissolved (ug/1)
0.07
0.01
Ibtal (ug/1)
0.14
0.03
Sediment (ugAg)
130
20
7.56
1,44

14.8
2.5

,000*
,200*
=

0.25
0.04

0.52
0.11

468*
72*
85.9
16.4

1 167.7
28.6

.147,200*
24,500*


2.9
0.41

5.7
1.2

-5r320*
820*
-. 11.3 128.8
2.2 24.5

-22.1 251.5
^X8 42.9

-5.4
0.9


0.38 4.3
0.05 0.6

0.79 8.6
0.16 1.8

0.20
0.03
   No known biological component for residue level.

-------
Table 7.  Residue estimates (ug/g) in biota due to bioconcentration and biomag-
          nification in the Houston Ship ChanneI/Galveston Bay .area* Texas from
          uncontrolled chloroparaffin releases
'?- Source of
Exposure
Water
Bioconcentration (BCF) Bicnagnification
Plankton . Filter U.5X BCF or PEC)
& Nekton " Feeders Detritus First-level Benthic
(3,600X) (40,900X) Feeders Planktivores Carnivores




Dissolved (ug/1)
0,76
0.67
0.60
0.56
~ 0.35
0.51
0.39
0.33
0.26
0.24
€.08
Total (ug/1)
1.4
1.3
1.2
-. 1.1
1.0
1.0
0.8
0.6
0.5
0.4
0.2
Sediment (ugAg)
1,300
1,200
1,000
950
940
870
700
570
450
420
140
2.7
2.4
2.2
2.0
2.0
1.8
1.4
1.2
0.9
0.9
0.3

5.0
-4.7
4.3
4.0
3.6
3.6
2,9
2.2
1.8
1.4
0.7

4,680*
4,320*
3,600*
3,420*
3,380*
3,130*
2,520*
2,050*
1,620*
1,510*
500*
31.1
^7.4
24.5
22.9
22.5
20.9
. 16.0
13.5
*- 10.4
.'- 9.8
3.3

57,3
53.2
49.1
45.0
40.9
*- 40.9
~ 32.7
24.5
20.5
16.4
8.2

53,200*
49,100*
40,900*
38,900*
38,450*
35,600*
. 28,600*
V 23,300*
- ' 18,400*
17,200*
5,730*
"4.1
3.6
3.2
3.0
' 3.0
2.8
2.1
, 1.8
1.4
1.3
0.43

7.6
"7.0
-6.5
5.9
5.4
5.4
4.3
3.2
2.7
2.2
1.1

2.0
1.8
1.5
1.4
1.4
1.3
1.1
0.9
0.7
0.6
0.2
46.6
- 41.1
36.8
34.4
33.7
31.3
23.9
20.2
16.0
14.7
4.9

85.9
79.8
73.6
67.5
61.4
61.4
49.1
36.8
30.7
24.5
12.3

3.0
2.8
2.3
2.1
2.1
2.0
1.7
1.4
U.l
1.0
.0.3
   JJo known biological conponent for residue level.

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Table 8.  "Residue estimates {ug/g) in biota due to bioconcentration and bicmag-
          nification in the Houston Ship Channel/Galveston Bay area, Ttexas from
          controlled chloroparaffin releases
Source of
Exposure
Water
Dissolved (ug/1)
0.06
0.03
0.03
0.02
0.02
0.02
0.02
0.01
0.01
fl.Ol
0.004
Total (ug/1)
0.12
0.06
0.05
0.05
0.05
0.04
0.03
0.03
0.02
0.02
'0.007
Sediment (ugAg)
100
50
_ 50
40
40
40
30
30
-20
20
10
Bioconcentration (BCF) Bionagnification
. Plankton Filter (1.5X BCF or PEC)
' & Nekton Feeders Detritus First-level Benthic
(3,600X) (40,900X) Feeders Planktivores Carnivores


0.22
0.11
0.11
0.07
0.07
0.01
0.07
0.04
0.04
0.04
0.01

0.43
0^22
0.1B
n.is
0.18
0.14
J).ll
0.11
0.07
0.07
0.03

360*
180*
180*
144*
144*
144*
108*
" 108*
-72*
-72*
36*


2.4
1.2
1.2
0.82
0.82
0.82
0.82
0.41
0.41
0.41
-' 0.16

-4.91
2.45
2.0^
2.05
2.05
1.64
1.2
1.2
0.82
0.82
0.28

4,090*
2,040*
2,040*
1,640*
1,640*
1,640*
1,230*
1,230*
820*
820*
410*


0.32
0.16
0.16
- o.ii
0.11
0.11
o.u
0.05
, . 0.05
0.05
0.02

0.77
0.32
0.27
0.27
0.27
0.22
0.16
0.16
0.11
0.11
0.04

~0.2
-Q.OB
0.08
0.06
0.06
0.06 "
0.04
0.04
0.03
0.03
0.02


3.7
1.8
-1.8
1.2
1.2
. 1.2
1.2
0.6
0.6
0.6
0.02

7.4
3.7
1.1
3.1
- 3.1
0.2
1.8
1.8
1.2
1.2
0.4












   No known .biological ccrponent for residue level.

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             fir-i&VfTr:•"•>'.  ..-•
                                                                      m
                                                                      •4-1
                                                                        0)
                                                                      en ro
                                                                        Sm
                                                                        Q
                                                                      r-t
                                                                      •P u

                                                                      2 §1
                                                                        e
                                                                        lu
5
U-i
O
                                                                        8
                                                                      U-i
                                                                      O 4J
*t  t•?»«. ,r t

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           -DIT7ALL
                                                 DIAMOND SHAMROCK
                                                    PMPBCJY
                                                                        «
Figure 2.  Map of sampling stations at Diamond Shamrock Manufacturing Plant
           on Patrick Bayou adjacent to the Houston Ship Channel in Texas.

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                                   •1. Mi M Mil

                                  HI lit IHi
                                   4 MI   j
                           (tn ttn mi ntt My MM

                       fctat M •MM** ItMnf

               MI tin m mi ntt IM m
iltif »M.«iMlfc* IMbt



     f
    H(^ \*HM MM m», MM

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Figure 3. ~-
-------
APPFNDIX A.  Chloroparaffin residue levels in the Schuykill River near
          Conchohocken, Pennsylvannia predicted by Versar Inc. (1985) based on
          uncontrolled and controlled release estimates.
                           Predicted Chlorowax 500-C Residue Levels
Segment Location
     Water          _1,344

 System self-purification time is roughly 27 months.
Controlled Residues

Below Discharge Point    0.000001      0.002          0.0005

 System self-purification time is roughly .27 months.
                                                  0.3

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APPENDIX A (cant.).  Chloroparaffin residue levels in Sugar Creek near Dover,
          Ohio predicted by Versar Inc. (1985) based on uncontrolled and
          controlled release estimates.

                          ' Predicted Chlorowax 500-C .Residue Levels
Sequent Location
Uncontrolled Releases
Discharge Point
Below Confluence
Water (ug/1)
Dissolved Total
2.1 4.1
- 0.4 0.7
Pediment (ppm)
•total
3.6
0.6
- ~Biota <
(pptn)
274
49
 System self-purification tune J.s roughly 4 months.
Controlled Releases

Discharge Point          0.07     .     0.14        "   0.13               10
Below Confluence         0.01     ~    0.03           0.02              ,1.7

 System self—purification tune is roughly 4 months.
                             Predicted Chlorowax 70 Residue Levels
* '
Segment 'Location
Uncontrolled Residues
Discharge Point
Below Confluence
- Water (ug/1)
Dissolved Total
0.06 7b
D.01 14
Sediment (ppm)
Total
20.5
3.9
Biota
(ppm)
10,550
2,003
 System self-purification tune is roughly.18 months.
Controlled Residues
                                                                   *
Below Discharge Point   ~0.00001       0.015          0.004               2.1
Below Confluence         0.000002      0.003          0.0008              0.4

 System self-purification time as roughly ISanonths.

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1SPPENDIX A (cent.).  ~Chloroparaffin residue levels in the Houston Ship Channel/
           Galveston  Bay area,  Texas predicted  by Versar Jnc. (1985) based on
        '   uncontrolled release estimates.
 Segment location
    Predicted Chlorowax 500-C Residue Xevels
     Water (ug/1)          Sediment (ppro)
Dissolved   •   Total          Total
                Biota
                (ppn)
 Uncontrolled Releases

 Houston Ship Channel     0."76
   (west of mouth of
   San Jacinto River)
Houston Ship Channel
   (west of Scott Bay)

Houston Ship Channel
   (west between Scott
   Bay and Tabbs Bay)
Houston Ship Channel    '0.56
   (between Tabbs Bay
.   and Morgans Point)
                1.4
1.3
                1.1
0.95
Upper most part of the   0.006
Houston Ship Channel
San Jacinto River
and Galveston .Bay

Lower Houston Ship
Channel and other areas
100
D.67
0.60
1.3
-1.2
1.2
1.0
87
"78
 72
Barbours Cut
San Jacinto River
Scott Bay
Tabbs Bay
Galveston Bay
Upper San Jacinto Bay
Bumet Bay
System self-purification

Uncontrolled Releases
0.55
0.39
0.51
0.33
0.26
0.24
0.08
tine


1.0
0.8
1.0
0.6
0.5
0.4
0.2
is roughly .28 months
Predict^ Chlorowax 70

0.94
0.68
O.R7
0.57
0.45
0.42
0.14

Residue Levels

71
51
66
43
34
32
10



                8.7            2.4             Ir233
                                        ^

 0.003  -  ,  .   3.8-4,0        1.1           545-571


 0.006        ~7.4-~7.5  .'    2.1      _-lf065-lf074
 Syston self-purafication tune as roughly 74 months.

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APPENDIX A  (cent.).  Thloroparaffin residue levels In the Houston Ship Channel/
          Galveston Bay area, Texas predicted by Versar Inc. (1985)  based on
          controlled release estimates.
Segnent Location
    Predicted Chlorowax 300-C Residue Levels
     Water (ug/1)         Pediment (ppm)      Biota
Dissolved      Total	Total	,   -  (pan)
Controlled Releases

Houston Ship Channel
  (west of mouth of
  San Jacinto River)

Houston Ship Channel
  (west of Scott Bay)

Houston Ship Channel
  (between Scott Bay
  and Tabbs Bay)

Houston Ship Channel
  (between Tabbs Bay
  and Morgans Point)

Harbours Cut

San Jacinto River

Scott Bay

Tabbs Bay

Galveston Bay

Upper San Jacinto Bay

Buznet Bay
  0.06
  0.02
0.12
0.05
0.10
0,04
8.0
0.03
D.03
0.06
0.05
0.05
0.05
3.9
3.5
3.2
0.02
D.02
0.02
0.01
0.01
0.01
0.004
0.05
0,03
0.04
0.03
0,02
0.02
0.007
0.04
- 0.03
0.04
0.03
0.02
0.02
0.01
3.7
2.0
2.9
1.9
1.5
1.4
0.5
             purification tine is roughly 20 months.
Houston Ship Channel

San Jacinto River
and Galveston Bay

Lower Houston Ship
Channel and other areas
0.000002
0.0000006
0.000001
0.003
0.0007-8
O.D001
0.0008
^
,0.0002
,0.0004
0.4
0.1
0.2
 System self-purification tune is roughly 53 months.

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APPENDIX ft.  Results o£ Phase II testing of 58 % Chlorinated Short-Chain  Length
           additional species.
                                                                                        H-Paraffins on
   Test Species
                        Test Type
LC50
Overall MATC
    MATC       MATC
Hatchability Survival
  (percent)  (percent)
     MATC
  % Growth Rate1
Length	  Weight
Sheepshead Minnow
Cyprinodon variegatud
                       Bnbryo-ldrvae
                       (Study « 1)
                       (Study * 2)
       > 2.4 < 4.1-55 ugA  > 55 UgA    > 55 ug/1 >  2.4  -      >  2.4
       (increased growth)   (77-95)  (68-90,    53 ug/1  <4.1-55 Ug/1
                           .,           88 -100)   (4  -7  %     (14 - 31  *
                      r                             increase)     increase)
                                                 < 36-71 < 162 ug/1
                                                (increased growth)
                                                 , > 280  < 620 ug/1
                                                (reduced growth)
                           > 620 ug/i   >  62rt Ug/1   <  36-  71      <  36- 71
                            (80 - 95) (65.8- 90.7,  < 162 Ug/1   <  162 ug/1
                                       75.8-100)   (5 - 7 %     (15  - 21 %
                                                   increase)     increase)
                                                   > 280 -  .    > 280 -»
                                  ,   .              < 620 Ug/1   <  620 ug/1
                                                   (9  % red.)   (31% red.)
Waterflea
Daphnia tnagna
                       Lite-cycle       530 ug/1*
                                         46 ppb
                                    (48-hr EC50)
                                        12 ug/1*         s o.-» ug
                               > 8.9 < 16.3 ug/1    (66 * red. in
                                 (6-21 day EC50)    total reprod.)
           •'"  < 2.7 ug/1*  < 2.1 ug/1*
          (reduced young    (44 % red.
            per female)      offspring
                 < 8.9 ugA*  /female)
                   • - *
                               i
Mysid Shrimp           Life-cycle
Mysidopsia bahia
Midge                  Life-cycle
Chironcmus tentans
                                       14.1 ug/1*
                                     < 14.1 ug/1
                                     (96-hr LC50)
                                      > 16? ug/1
                                     (4B-hr TC50
                                      no deaths)
          > 7.3 < 13.7 ug/1* > 5.0 -
          > 0.6 <  1.2 ug/1  < 7.3 ugA
          (sign, parental
             mortality)
                                                                      (33 % red,
                                                                      offspring
                                                                      /female)
           > 60  <  78 ug/1
           (red. hatching)
                    > 60 -
                    < 78 ug/1
                   (60 * red.
                    hatching)
                               > 5.0 -    > 8.4 ug/1*
                               < 8.9 ug/1* (1 * red.)
                               (37 I dead
                                offspring
                               not sign.)
              > 0.6 -   > 7.3 ug/1  > 7,3 ug/1
              < 1.2 ug/1  ( I %      ( 0.4 % -
              (40-50 %   increase)  reduction)
              parental
               deaths)    '

                >,78 -    < 78 ug/1  < 78 ug/1
               < 121 ug/1  (10 %        (1 %
                 (no       red. in     red. In
               emergence) eggs/mass)    hatch)
   Data value cart hot he used with confidence.

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APPENDIX B  (cont.)
   fesk Species
      Type
  LC50
        MATC
                                         :  1,310 ug/1*
                                         >,1,200 ug/1
                                         (10-day ECSO)
     Cell Growth
   (particle count)
Green Algd Acute
Selenastnjm <•'
capricornatum
'3,690 Ug/i*
y 1,200 ug/1
(96-hr EC50)
> 390 < 570 ug/i
(35 % reduction
in growth)
> 390 < 570 ug/1
(35 % reduction
in cell growth)
Marine Alga
Skeletonewa
costatun
Acute
   il.fi ug/1
 (48-hr EC50)


  ,42.3 ug/1
 (96-hr BC50)
  j
 > 69.fi ug/i
(10-day FC50)
 > 12. 1 < 19.6 ug/1
1  (44 % reduction
in growth on Day ?)

 > 19.6 < 43.1 ugA
(Day 4 - 34 * red.)
                                                                 >, 69. B
                                                        (Day 10 - ho sign.)
 > 12.1 < 19.6 ug/1
 (44 % reduction
in growth on Day 2)

 > 19.6 < 43.1 ug/i
(Day 4 - 34 % red.)

        > 69.8 Ug/i
(Day ib - no sign.)
*  Data can not be used with confidence.

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