MASTER TESTING LIST
December 1, 1996
OFFICE OF POLLUTION PREVENTION AND TOXICS
OFFICE OF PREVENTION, PESTICIDES AND TOXIC SUBSTANCES
U.S. ENVIRONMENTAL PROTECTION AGENCY
WASHINGTON, D.C. 20460
-------
MASTER TESTING LIST
Executive Summary
As stated in Section 2 of the Toxic Substances Control Act (TSCA), "It
is the policy of the United States that adequate data should be developed
with respect to the effect of chemical substances and mixtures on health and
the environment and development of such data be the responsibility of those
who manufacture and those who process such chemicals and mixtures."
Section 4 of TSCA gives EPA the authority to require chemical
manufacturers and processors to test existing chemicals. Under Section 4,
EPA can by rule require testing after finding that (1) a chemical may present
an unreasonable risk-of injury to human health or the environment, and/or the
chemical is produced in substantial quantities that could result in significant
or substantial human or environmental exposure, (2) the available data to
evaluate the chemical are inadequate, and (3) testing is needed to develop
the needed data. The Chemical Testing Program in EPA's Office of Pollution
Prevention and Toxics (OPPT) also works with members of the U.S. chemical
industry to develop needed data via TSCA Section 4 Enforceable Consent
Agreements (EGAs) and Voluntary Testing Agreements (VTAs). EGAs and
VTAs are usually less resource intensive than formal TSCA rule-making and
allows EPA to consider agreed-upon pollution prevention and other types of
product stewardship initiatives by the chemical industry as a possible
substitute for or adjunct to certain types of needed testing.
OPPT has been using the Master Testing List (MTL) since 1990 to
establish its TSCA Existing Chemical Testing Program agenda. The MTL
presents a consolidated listing of OPPT's existing chemical testing priorities
as well as those of other EPA Program Offices, other Federal agencies, the
TSCA Interagency Testing Committee, and international organizations such
as the Organization for Economic Cooperation and Development (OECD).
The main purposes of the MTL are to (1) identify chemical testing
needs of the Federal Government (including EPA) and relevant international
organizations (e.g., OECD), (2) focus limited EPA resources on the highest
priority chemical testing needs, (3) publicize the testing priorities for
industrial chemicals, (4) obtain broad public input on OPPT's TSCA Chemical
Testing Program and its priorities, and (5) encourage voluntary initiatives by
the U.S. chemical industry to fill the priority data needs that are identified on
the MTL.
-------
EPA believes that companies with-product stewardship programs will
recognize the importance of promptly filling the data needs identified via the
MTL because they know a database that is inadequate to support risk
assessment deprives people who are exposed to a chemical of their right to
know about the hazards/risks that may be posed by that chemical substance.
The identification of testing needs on the MTL provides an opportunity for
responsible companies to initiate voluntary activities to develop the needed
data for their own MTL-listed chemicals. In those instances in which
companies decline to take this opportunity, EPA is put in a position of having
to initiate formal, resource intensive, regulatory actions such as promulgating
TSCA Section 4 Test Rules. Issuance of such rules can be viewed as
"forcing" chemical companies to adhere to their own professed standards of
product stewardship and corporate responsibility.
The MTL contains over 500 individual existing chemicals and more
than 10 existing chemical categories and presents EPA's TSCA Chemical
Testing Program priorities for 1996-1998. Testing actions are currently
being developed on more than 200 chemicals listed on the MTL while testing
is currently underway on almost 300 chemicals identified on the MTL. In
addition, more than 100 chemicals are being removed from the MTL at this
time, over 70 of those because their testing programs have been completed.
It is also important to note that the Chemical Testing Program and the
MTL are integral components of OPPT's TSCA Existing and New Chemicals
Programs. These programs are responsible for assessing and managing
health and environmental risks that may be posed by existing and new
chemicals covered by TSCA. The "universe" of existing chemicals on the
TSCA Chemical Substances Inventory that may present the greatest potential
health and/or environmental concerns have been and continue to be
identified and refined through various existing chemical screening activities
within OPPT.
-------
MASTER TESTING LIST
Table of Contents
Executive Summary
Introduction
Additions to the MTL
Removals from the MTL
Format for the MTL
Participating in the TSCA Chemical Testing Program
Appendix I. (TSCA Existing Chemicals Program Overview)
PAGE
i
1
6
16
19
25
27
Master Testing List Indices
INDEX I. Chemicals Listed on the MTL (Includes Removals)
INDEX II. Chemicals Removed from the MTL (Includes Removal Rationale)
in
-------
IV
-------
MASTER TESTING LIST
Introduction
Background
Under the Toxic Substances Control Act (TSCA), EPA is given broad
authority to issue regulations designed to gather health/safety and exposure
data on, require the testing of, and control exposure to chemical substances
and mixtures. Drugs, cosmetics, foods and food additives, pesticides, and
nuclear materials are exempt from TSCA and are subject to control under
other Federal statutes (e.g., foods, food additives, drugs and cosmetics are
under the purview of the Federal Food, Drug, arid Cosmetic Act (FFDCA)
which is administered'by. the U.S. Food and Drug Administration (FDA)).
It is important to note that TSCA has differing mandates regarding the
regulations for "existing" chemicals (i.e., those already in U.S. commerce)
and "new" chemicals (i.e., those not yet in U.S. commerce). Therefore,
when TSCA became effective on January 1, 1977, it was imperative that
EPA be able to distinguish between existing chemicals and new chemicals.
This was accomplished by using TSCA Section 8(a) information reporting
requirements to create the TSCA Chemical Substances Inventory. The TSCA
Inventory is a compilation of the names of all existing chemical substances
along with their respective Chemical Abstract Service (CAS) Registry
numbers and certain other types of information (e.g., production/importation
volume ranges, specific sites of production/importation). After 1977, a
producer or.importer of a "new" chemical (i.e., one that is not listed on the
TSCA Inventory) is required to submit a TSCA Section 5 "Pre-Manufacture
Notice" (PMN) to the New Chemicals Program in the Office of Pollution
Prevention and Toxics (OPPT) in EPA's Office of Prevention, Pesticides and
Toxic Substances (OPPTS). (For more information about the New Chemicals
Program, the reader is directed to an article by Moss et al. which appeared in
the January/February 1996 issue of Chemical Health and Safety published by
the American Chemical Society.)
The Master Testing List (MTL) is an important component of EPA's
Existing and New Chemicals Programs under TSCA. The Existing Chemicals
Program is responsible for assessing and managing health and environmental
risks that may be posed by existing chemical substances covered by TSCA.
The "universe" of existing chemicals on EPA's TSCA Inventory that may
present the greatest potential health and/or environmental concerns
1
-------
(including testing needs) have been and continue to be identified and refined
through various screening activities within OPPT. This latest version of the
MIL also includes priority testing and actions derived from the TSCA New
Chemicals Program.
The TSCA Inventory currently contains over 70,000 existing
chemicals, many of which are produced or imported at low or negligible
volumes, while others are polymers which, because of their physical size
(e.g., high molecular weight) and other characteristics, are unlikely to present
significant risk concerns. By excluding low volume chemicals (-25,000
chemicals produced or imported in amounts less than 10,000 pounds per
year) and polymers (which tend to be poorly absorbed by organisms and
therefore typically exhibit low toxicity), the remaining TSCA Inventory is
comprised of about 15,000 non-polymeric chemicals produced/imported at
levels above 10,000 pounds per year.
Of these 15,000 non-polymeric chemicals, there are 3,000-4,000
chemicals that are produced/imported in amounts over 1 million pounds per
year; these.chemicals are considered by EPA to be U.S. High Production ,
Volume (HPV) chemicals. EPA has identified this 15,000 chemical subset as
being the broad focus "universe" of the TSCA Existing Chemicals and
Chemical Testing Programs with the primary focus placed on the 3,000-
4,000 HPV chemicals. (See Figure 1.) This screening and testing approach
is supported by an U.S. Office of Technology Assessment (OTA) report
entitled "Screening and Testing Chemicals in Commerce" (OTA-BP-ENV-166;
September, 1995). For more information with regard to the TSCA Existing
Chemicals Program, the reader is directed to Appendix I ("EPA's Existing
Chemicals Program - An Overview").
Chemical Testing Under TSCA
Section 4 of TSCA gives EPA the authority to require chemical
manufacturers and processors to test existing chemicals. Under Section 4,
EPA can by rule require testing after finding that (1) a chemical may present
an unreasonable risk of injury to human health or the environment, and/or the
chemical is produced in substantial quantities that could result in significant
or substantial human or environmental exposure, (2) the available data to
evaluate the chemical are inadequate, and (3) testing is needed to develop
the necessary, data. The TSCA Chemical Testing Program also continues to
work with members of the U.S. chemical industry to develop needed test
data via TSCA Section 4 Enforceable Consent Agreements (EGAs) and
-------
Voluntary Testing Agreements (VTAs). EGAs and VTAs are usually much
less resource intensive than formal TSCA rule-making and allow the Agency
to consider agreed-upon pollution prevention and other product stewardship-
related initiatives by the industry as a possible substitute for or adjunct to
certain types of needed chemical testing.
Since 1979, approximately 540 of the 1 5,000 chemical sub-set of the
TSCA Inventory have been the subject of testing actions within the OPPT
Existing Chemicals Testing Program. Virtually all of the 540 chemicals are
"HPV chemicals." The testing actions taken to date include a mix of formal
TSCA Section 4 Test Rules and Section 4 Enforceable Consent Agreements,
and Voluntary Testing Agreements. More than 50% of these testing actions
have been taken in the last several years and have focussed on chemicals
with clearly identified data "needs" (as opposed to simply data gaps). In
addition, almost 250 formal TSCA Section 4 "Decisions Not To Test" (DNTs)
have been issued by EPA to date. Screening efforts to identify priorities and
determine testing needs for other chemicals are currently underway in OPPT.
i
Master Testing List
EPA has been using the Master Testing List (MTL) since 1990 to set
OPPT's Chemical Testing Program agenda. The MTL presents a consolidated
listing of OPPT's existing chemical testing priorities under TSCA and also
includes the priority industrial chemical testing needs of OPPTS, other EPA
Program Offices (e.g., Office of Air and Radiation, Office of Water), other
Federal agencies (e.g., U.S. Occupational Safety and Health Administration,
U.S. Consumer Product Safety Commission, U.S. Department of the Interior),
and the TSCA Interagency Testing Committee (ITC).
The purposes of the MTL are to (1) identify chemical testing needs of
the Federal Government (including EPA) and international programs of
interest to the U.S., (2) focus limited EPA resources on the highest priority
chemical testing needs, (3) identify and publicize EPA's testing priorities for
industrial chemicals, (4) obtain broad public comment on EPA's Chemical
Testing Program and its priorities, and (5) encourage voluntary initiatives by
members of the U.S. chemical industry to provide EPA with the priority data
identified via the MTL as being needed.
Companies with product stewardship programs will recognize the
importance of promptly filling the data needs identified via the MTL because
they know a database that is inadequate to support risk assessment deprives
-------
people who are exposed to a chemical substance of their right to know the
hazards/risks that may be posed by that chemical. The identification of
testing needs on the MTL provides an opportunity for responsible companies
to initiate voluntary data development activities to develop the needed data
for their own MTL-listed chemicals. Companies that are good product
stewards will carefully evaluate and in many cases voluntarily meet the
testing needs identified via the MTL. EPA believes that to the extent
companies decline this opportunity, they are not living up to their own
professed standards of corporate responsibility. In those instances in which
voluntary testing is not undertaken, EPA is put in a position of having to
initiate a formal, resource intensive, regulatory action such as promulgating a
TSCA Section 4 Test Rule. EPA's issuance of such a rule can be viewed as
"forcing" companies to adhere to their own product stewardship principles.
The MTL presents EPA's TSCA Chemical Testing Program priorities for
1996-1998 and includes over 500 individual existing chemicals and more
than 10 existing chemical categories. Testing actions are currently being
developed on more than 200 of the chemicals listed on the MTL while
testing is currently underway on almost 300 other chemicals on the MTL. In
addition, over 100 chemicals are being removed from the MTL at this time,
more than 70 of those because of completion of their testing programs. It
should be noted that a number of chemicals are found more than once on the
MTL as the result of different testing actions that have been or are being
developed on those chemicals. .
This version of the MTL also includes information about EPA's TSCA
New Chemicals Program (NCP). The TSCA NCP is responsible for reviewing
new chemical substances prior to their entry into U.S. commerce. While
testing of new chemicals can be required by way of an action under Section
5(e) of TSCA, the NCP has also had success in developing voluntary testing
programs with the affected industry. Many of the new chemicals that have
been or are being tested are members of the NCP's "Chemical Categories."
Since 1979, EPA action under TSCA Section 5{e) has resulted in the
generation of needed health and/or environmental effects data on over 1000
new chemicals. The required studies have been split evenly between health
effects tests and environmental effects tests. Some environmental fate and
physical/chemical properties testing has also been required. Additional
information about the contributions of the TSCA NCP to the EPA's overall
TSCA Chemical Testing Program are expected to appear in future iterations
of the MTL.
-------
Figure 1. Existing Chemical Universe Chart
Chemicals Produced
@
< 10,000 Pounds/Year
(-25,000 Chemicals)
TSCA Inventory
(-70,000 Chemicals)
Polymeric Chemicals
(Typically Non-Toxic)
(-30,000 Chemicals)
Chemicals Produced
, @
> 10,000 Pounds/Year
(-15,000 Chemicals)
Chemicals Produced
> 1 Million Pounds/Year
(-3-4,000 HPV
. Chemicals) .
-------
I. ADDITIONS TO THE MTL SINCE 1992
A. Specific Chemical Substances
The following provides a brief overview of trie-specific chemicals that
have been added to the MTL since 1992:
o One-hundred and forty-one (141) chemicals from the international
Organization for Economic Cooperation and Development (OECD)
"Screening Information Data Set" (SIDS) voluntary testing program;
o Eighty-three (83) chemicals designated by the TSCA Interagency
, Testing Committee (ITC) for skin absorption rate testing in its. 31st,
32nd and 35th Reports to EPA; however, the designation for 3 of the
subject chemicals was subsequently withdrawn by the ITC and the
chemicals were removed from the MTL;
N
o One (1) chemical (white phosphorus) designated by the ITC for
ecological effects testing in its 34th Report to EPA; however, the
TSCA Section 4 testing designation for white phosphorus was
subsequently withdrawn by the ITC and the chemical was removed
from the MTL. In 1996, white phosphorus was added back to the MTL
because EPA is trying to obtain ecological effects testing needed by
the Department of the Interior via a mechanism other than a formal
TSCA Section 4 rule-making activity;
o Twenty-three (23) chemicals from the EPA Office of Air and Radiation
(OAR) Clean Air Act Amendments (CAAA) Section 112 "Hazardous Air
Pollutants" (HAPs) category described in Section B. below;
o Thirteen (13) chemicals (10 organics and 3 metals) from the Agency
for Toxic Substances and Disease Registry (ATSDR) Superfund
Amendments and Reauthorization Act (SARA) Section 104 category
described in Section B. below; v
i
o One (1) chemical (alkyl C12-C13 glycidyl ether) from the "Glycidol and
Its Derivatives" category of chemicals originally designated for health
effects testing under TSCA Section 4 by the ITC in its 3rd Report to
the EPA Administrator;
-------
o Four (4) high production volume, high exposure chemicals from the
Toxic Release Inventory (TRI) Screening category described Section B.
below;
o Six (6) siloxanes from a comprehensive industry testing program
established via a voluntary "Memorandum of Understanding" (MOU)
between EPA and the Dow Corning Corporation;
o Three (3) dibasic esters (DBEs) used as substitutes for methylene
chloride in paint stripping products; the testing action on DBEs, which
are among the chemicals in EPA's ongoing assessment of paint
stripping products and their components, is being developed at the
request of the U.S. Consumer Product Safety Commission (CPSC);
o Three (3) chemicals from EPA's Office of Air and Radiation (OAR)
Oxygenated Fuel Additives (OFAs) category described in Section B.
below;
o One (1) chemical (aniline) from an industry testing program being
conducted on a voluntary basis;
o One (1) chemical (branched 4-nonylphenol) as the result of a formal
OPPT TSCA Existing Chemical Program Risk Management (RM-1)
disposition;
o Five (5) chlorofluorocarbon substitutes from EPA's TSCA New
Chemicals Program (NCP) Chemical Categories described below;
o Fifteen (15) acrylates/methacrylates from EPA's TSCA NCP Chemical
Categories described below;
/
o Two (2) fluorescent whitening agents from EPA's TSCA NCP Chemical
Categories described below;
o Two (2) vinyl esters from EPA's TSCA NCP Chemical Categories
described below; and
\
o Ten (10) peroxides from EPA's TSCA NCP Chemical Categories
described below.
-------
B. Categories
The following categories have been targeted by EPA for testing needs
and/or testing action development; the categories that are currently on the
MTL (including those that have been added to the MTL since 1992) are as
follows:
>
,1. Persistent Bioaccumulators
Many chemicals that possess persistent and bioaccumulative properties
have been found to present significant environmental problems.
Emerging concerns in EPA, especially in the Office of Water, focus on
sediments contaminated with chemicals having these characteristics.
OPPT plans toTequire the development of environmental fate and
ecotoxicity test data on these chemical substances to support a more
comprehensive risk assessment. OPPT is in the process of identifying
the set of chemicals that will be addressed under this effort and the
types of testing needed.
/
2. New Chemicals Program "Chemical Categories"
EPA's New Chemicals Program has established 47 chemical categories
for which TSCA section 5(e) risk determinations have been made
based upon health or environmental concerns identified through
structure-activity relationships (SAP). These chemical categories were
established to facilitate the TSCA Section 5 "Pre-Manufacture Notice"
(PMN) review/regulatory process and represent part of a general effort
by EPA to promote development of safer chemicals. EPA is continuing
to refine the boundaries and definitions of such categories and engage
the chemical industry in dialogue directed toward development of
fociissed testing programs on commercially promising new chemicals
and/or structurally-related existing chemicals. The resulting test data
are valuable to EPA as well as the industry for hazard identification,
risk management, and the design of safer substitutes. Properly
conducted, strategic testing of one or more members of a category can
often be used to evaluate the toxicologic potential of an entire class of
commercially promising compounds from that category. The following
discussion provides a brief overview of the OPPT New Chemicals
Program "categories" that are now listed on the MTL, namely:
Chlorofluorocarbon Substitutes, Acrylates/Methacrylates, Vinyl Esters,
Fluorescent Whitening Agents, and Peroxides.
8
-------
a. CHLOROFLUOROCARBON SUBSTITUTES
Since 1989, OPPT's New Chemicals Program has been working
closely with EPA's Office of Air and Radiation (OAR) to 1) coordinate
identification of and provide a more thorough and consistent EPA
review of health and environmental effects of "new" chemical
substances that can be used as substitutes for ozone-depleting _,
chlorofluorocarbons (CFCs); and 2) develop regulatory strategies for
controlling commercial introduction of these substitutes in order to
address toxicological concerns as well as OAR issues such as ozone
depletion and global warming. OAR participates in OPPT's New
Chemicals Program process at the earliest review stages and regulatory
strategies are developed to meet the requirements of both the Toxic
Substances Control Act (TSCA) and the Clean Air Act (CAA). Among
the regulatory tools used by OPPT in dealing with "new" CFC
substitutes are "Consent Orders" issued under Section 5(e) of TSCA.
Section 5(e) Consent Orders are developed to require the manufacturer
or importer of a new CFC substitute to control exposure to that
chemical and/or conduct additional testing on that material. Another
TSCA regulatory tool that is used is the Section 5 "Significant New
Use Rule" which covers potential additional producers/importers and
users of that CFC substitute and may subject "new" uses of the
chemical to further EPA review and/or control. Interactions between
OPPT and OAR have reduced duplicative review efforts resulting in
substantial resource savings for EPA while industry benefits from a
coordinated regulatory program that simultaneously addresses the
concerns of both EPA offices. In order to supply EPA with needed
toxicological data to assess the potential hazards that may be posed by
exposure to CFC substitutes, and in addition to conducting toxicity
studies that are required by EPA via TSCA Section 5(e) Consent Orders
on 3 "new" CFC substitutes, the chemical manufacturers who are
members of the international Program for Alternative Fluorocarbon
Toxicity (PAFT) agreed in the late 1980'sto conduct a comprehensive
voluntary testing program on two existing chemical substitutes
(namely, 1,1,1,2-tetrafluoroethane[HFC-134a] and 2,2-dichloro-1,1,1-
trifluoroethane,[HCFC-123]). The PAFT testing program was reviewed
and accepted internationally by authorities in the U.S., the European
Union and Japan. This understanding provided additional certainty to
industry developing these chemicals. PAFT's voluntary testing
program is still underway and includes studies designed to develop
data on genotoxicity, acute toxicity, subacute toxicity, subchronic
-------
toxicity, neurotoxicity, reproductive/developmental toxicity, and
oncogenicity. In addition to conducting these toxicological studies 6vn
a voluntary basis, PAFT has been distributing copies of the study
reports publicly.on a world-wide basis.
b. ACRYLATES/METHACRYLATES
Based on cancer concerns, "new" chemical substances in the
category of acrylates (including methacrylates) are being regulated by
EPA under Section 5 of TSCA. Following discussions with OPPT staff
regarding these regulations, the industry members of the Specialty .
Acrylates Manufacturers (SAM) offered to conduct a voluntary testing
program on 13 "existing" acrylates in exchange for some concessions
by EPA in regulating new acrylates under Section 5. As the result of
negotiations with SAM, OPPT agreed not to require a cancer warning
on product labels for new acrylates regulated by EPA; however, cancer
warnings, would still appear on the Material Safety Data Sheets
(MSDSs) for these chemicals. For its part, SAM agreed in 1990 to
conduct a voluntary testing program involving physical/chemical
properties and metabolism/pharmacokinetics testing on 13 existing
acrylates and cancer bioassays on 2 of those chemicals. SAM's
voluntary testing program was completed in September of 1995 and
the results of the tests are currently under review by OPPT.
c. VINYL ESTERS
A vinyl ester is a carboxylic acid ester with at least 1 vinyl
group (CH2 = CH-) attached to an organic acid radical (RCOO-). In
1992, the chemical industry initiated a testing program designed to
evaluate a new generation of vinyl esters submitted to EPA's New
Chemicals Program under Section 5 of TSCA. These vinyl esters are
being developed to replace lower molecular weight acrylates (see
preceding discussion on Acrylates/Methacrylates). The testing
program.includes glove permeation, hydrolysis, non-protein sulfhydryl
("GSH") depletion, subchronic toxicity, and developmental toxicity
studies as well as cancer bioassays. EPA responded to this industry
initiative by agreeing not to require cancer warnings on product labels
for new vinyl esters regulated by the Agency under TSCA Section 5
(although cancer warnings still appear on the Material Safety Data
Sheets (MSDSs) for these chemicals).
10
-------
d. FLUORESCENT WHITENING AGENTS
In EPA's TSCA Section 5 New Chemicals Program, fluorescent
whitening agents fall under the general chemical category of water
soluble (sulfonated) derivatives of 4,4-bis(triazin-2-ylamino)stilbene.
Testing program negotiations are currently- underway with members of
the Ecological and Toxicological Association of Dyestuffs and Organic
Pigments Manufacturers (ETAD) to conduct needed developmental and
reproductive toxicity studies on at least 2 representative stilbene-based
fluorescent whitening agents.
e. PEROXIDES
A molecule containing one or more of the following functional
groups is considered by the TSCA Section 5 New Chemicals Program
to be a member of the "peroxides" category: dialkyl peroxide, alkyl
hydroperoxide, peroxy ester, diacyl peroxide and peroxy acid. The
typical "new" peroxide is a discrete (Class I) chemical with a molecular
weight of less than 500. The chemical industry is currently developing
and conducting a number of short term tests to predict/assess potential
tumor promoting and/or carcinogenic activities of 10 organic peroxides.
The test systems being developed are: (1) test tube (in vitro) assays
for detecting free radical formation, and (2) mouse skin assays for
sustained inflammatory/hyperplastic response. In addition to the test
tube assays, EPA has suggested use of a human skin cell culture to
look for evidence of free radical formation. A series of structurally
different new and existing peroxides are being studied in this voluntary
testing program and the results are expected to allow correlation of the
types and levels of free radicals formed and how damage caused by
free radicals may relate to either tumor promoting and/or carcinogenic
activity or inactivity. :
3. EPCRA Section 313 ("TRI Screening")
The Toxics Release Inventory (TRI) was established under section 313
of the "Emergency Planning and Community Right-to-Know Act"
(EPCRA). Under a voluntary cooperative effort with the Chemical
Manufacturers Association (CMA) and possibly other chemical trade
associations, a subset of at least 10 TRI chemicals produced and
released in high volumes will be evaluated and screening level testing
developed using the Organization for Economic Cooperation and
11
-------
Development (OECD) Screening Information Data Set (SIDS) model.
Thus far, the U.S. chemical industry has agreed to conduct SIDS
testing on 4 TRI chemicals. EPA has asked the industry to complete
its commitment by selecting at least 6 more "high production/high
release" TRI chemicals for SIDS testing.
4. Clean Air Act Section 112 "Air Toxics" (Hazardous Air Pollutants)
Data are needed by EPA's Office of Air and Radiation (OAR) and Office
of Research and Development (ORD) to determine the "residual risk"
posed by the 189 chemicals (Hazardous Air Pollutants (HAPs)) listed
under section 112 of the Clean Air Act Amendments of 1990. The
MTL now includes the initial list of 23 chemicals from this category for
which testing has been proposed under Section 4 of TSCA (see 61 FR
' 33178; June 26, 1996). Testing needs for other chemicals in this
category are currently being determined in a cooperative effort
between OPPT, OAR and ORD. EPA's primary use of the data from
this testing activity will be to implement several provisions of section
112 of the Clean Air Act (CAA), including determining residual risks
(e.g., assessing risks remaining after imposition of technology- based
emission standards (maximum achievable control technology standards
or "MACT" standards)), estimating risks associated with accidental
chemical releases, and determining whether or not subject chemicals
should be removed ("delisted") from the CAA section 112(b) HAPs list.
Other important uses of the data obtained via this testing activity are
to: 1) help in better informing communities and citizens about chemical
hazards in their own localities, 2) assist state and local permitting
authorities establish appropriate standards within their programs, and
3) help other EPA Program Offices and other Federal agencies in
assessing chemical risks and taking appropriate action(s) within their
own programs and under the Federal statutes that they administer.
5. SARA Section 104 "Priority Data Needs"
Section 104 of the Superfund Amendments and Reauthorization Act
(SARA) requires EPA and the Agency for Toxic Substances and
Disease Registry (ATSDR) to list chemicals frequently identified in
Superfund sites. ATSDR is charged with preparing "Toxicological
Profiles" for these chemical substances, identifying data gaps and
research needs, and developing a testing/research program. When and
where appropriate, EPA's TSCA (or Federal Insecticide, Fungicide and
12
-------
Rodenticide Act (FIFRA)) authorities are to be used to obtain the
necessary data. There are 250 chemicals and categories now listed
under SARA Section 104 and Toxicological Profiles have been
published or are being prepared by ATSDR on 215 of these chemicals.
and categories. ATSDR has identified priority data needs for the first
subset of 13 chemicals (3 metals and 10 organics). These chemicals
are listed on the MTL and testing needs/testing action development is
currently underway in EPA's Chemical Testing Program.
6. Respirable Fibers
Man-made and naturally-occurring fibers with diameters |ess than 3.5
micrometers that can enter the small airways of the lower respiratory
tract and survive in biological systems for long periods of time can
present significant health concerns. EPA is assessing the potential
risks associated with the production and use of synthetic and naturally-
occurring respirable fibers and products made from such fibers. The
testing likely to be proposed by EPA will focus on health effects via
inhalation and better characterization of exposure.
7. Indoor Air Source Characterization - Carpet/Carpet-Related Products
An agreement with industry has been reached to generate the test data
needed for characterization of Total Volatile Organic Compound
(TVOC) emissions from carpets and carpet-related products (i.e., carpet
cushion and carpet adhesives). The emissions testing program was
developed via EPA's Carpet Policy Dialogue and testing was initiated in
1991 (See 56 FR 67317; December 30, 1991). the final results from
the carpet TVOC study have been received by EPA and this entry
(Carpet-TVOC) has been removed from the MTL. The voluntary testing
programs for both carpet cushion and carpet adhesives are still
underway.
8. Indoor Air Source Characterization - Interior Architectural Coatings
OPPT and EPA's Office of Air and Radiation (OAR) are continuing to
coordinate efforts to characterize and determine specific needs for
chemical emissions and total emissions testing for indoor air sources
such as paints, varnishes and other types of interior architectural
coatings. ;
13
-------
9. Polychlorinated Dioxins/Furans in Wood Pulp/Paper Mill Sludge
Polychlorinated dioxins and furans (D/F) are produced when wood pulp
is bleached with chlorine or chlorine-derivative compounds. The sludge
that results from the wastewater treatment process in pulp and paper
mills has been found to be contaminated with D/F. EPA has identified
concerns for possible adverse human health and environmental risks
posed by the disposal of this sludge through land application and has
determined that additional testing and monitoring data to evaluate such
risks are needed. Under the terms of a voluntary agreement with EPA,
four pulp and paper mills are evaluating their sludge for D/F
concentrations and are engaged in numerous other types of product
stewardship activities (e.g., labeling, modifying land application
practices). Under the terms of another voluntary agreement with EPA,
the American Forest and Paper Association is collecting, aggregating
and submitting data from the mills to EPA and coordinating industry's
outreach efforts on this voluntary testing/stewardship program.
10. Endocrine Disrupters (New Category)
Endocrine disrupters are chemicals that interfere with normal hormone
system functioning. These substances can have adverse impacts on
growth and development, sexual differentiation, and a host of
biological functions that are controlled through the endocrine system.
One of EPA's primary efforts for endocrine disrupters involves the
establishment of a dialogue with industry and other major stakeholders
(including other Federal agencies) to formulate a cooperative screening
and testing program designed to identify chemicals that can disrupt
endocrine function(s) and determine the risk they may pose to health
and/or the environment. In addition, Section 405(p) of the 1996 Food
Quality Protection Act (FQPA) requires that EPA develop (within 2
years) and implement (within 3 years) an estrogenic effects screening
program for all pesticides using validated test methods. The FQPA
also gives EPA the authority to require testing of other chemicals "that
may have an effect that is cumulative to an effect of a pesticide." The
FQPA states that data can be obtained via Section 3(c)(2)(B) of the
Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), Section 4
of TSCA, or an "order" if it can be shown that neither FIFRA nor TSCA
can be applied. Similarity the newly amended Safe Drinking Water Act
(SDWA) gives EPA authority to require testing of substances found in
drinking water and to which there may be substantial exposure.
14
-------
11. Machining Fluid Products/Chemicals (New Category)
Machining fluids, which are also known as metalworking fluids, are
used to lubricate and cool industrial equipment and the metal being
shaped during a variety of machining operations. These activities
include metal removal operations such as cutting or drilling and metal
forming operations such as stamping or drawing. The exposure to
metalworking fluids is primarily occupational and recent estimates
indicate that up to 10 million workers may be exposed to these types
of products, primarily via inhalation and dermal contact with mists.
There may be as many as 400 different commercial products belonging
to one or more of the four major metalworking fluid types: straight oils,
soluble oils, semi-synthetics and synthetics. All but the synthetic
.fluids contain mineral oil as a component and there are no standard
formulations of chemical components among commercially available
machining fluids. In response to a TSCA Section 21 petition that was
filed by the International Union, United Automobile, Aerospace and
Agricultural Implement Workers of America-UAW (UAW), EPA formed
an interagency workgroup with the. National Institute for Occupational
Safety and Health (NIOSH) and the Occupational Safety and Health
Administration (OSHA) to identify specific testing candidates and
testing needs for machining fluids. In addition, the Federal workgroup
has begun discussions with the UAW, the Independent Lubricant
' Manufacturers Association (ILMA), and others regarding development
and implementation of a testing program for machining fluid products
and their components.
12. Paint Stripping Products Use Cluster (New Category)
In 1993, OPPT concluded a risk assessment on N-methyl pyrrolidone
- (NMP), a methylene chloride substitute in some paint stripping
products, and, as a followup to that assessment, began a more broad-
based assessment of paint stripping chemicals/products that are
commonly available to consumers. As the result of concerns that were
raised by EPA and others, and in recognition of the tenets of product
stewardship, the NMP Producers Group spearheaded a voluntary effort
by the "Ad Hoc Industry Committee for Safe Paint Stripping" to design
and conduct a glove permeability testing program. Under this program,
numerous glove types are being tested against a variety of paint
stripping formulations used by consumers and small paint stripping
shops. This voluntary testing program is designed to assess the
; 15
-------
effectiveness of dermal protection offered by gloves of the type
commonly available to consumers through hardware stores. After the '
testing program is completed, the industry plans to incorporate the
results of the glove permeability testing in improved product labels and
other consumer education materials, in addition, EPA is developing a
testing action for the U.S. Consumer Product Safety Commission
(CPSC) on the following 3 dibasic esters (DBEs) which are used as
substitutes for methylene chloride in commercial paint stripping
products: dimethyl adipate, dimethyl succinate, and dimethyl glutarate.
The data from the DBEs testing program will also be used to support
OPPT's ongoing assessment of paint stripping products and their
constituents.
13. Oxygenated Fuel Additives (New Category)
EPA's Office of Air and Radiation (OAR/EPA) in the administration of
section 211 of the Clean Air Act (CAA), has requested OPPT to use its
TSCA section 4 testing authority to obtain health effects data on a
number-of Oxygenated Fuel Additives (OFAs) such as ethyl t-butyl
ether (ETBE) and t-amyl methyl ether (TAME)). These data are needed
by EPA and others to increase understanding of the toxicity of these
substances individually and in comparison to each other as well as to
other OFAs such as methyl t-butyl ether (MTBE). EPA is also currently
exploring options for obtaining toxicity data on diisopropyl ether (DIPE)
and t-butyl alcohol (TEA) before these chemicals come into wide use
as OFAs. In addition, EPA is attempting to obtain test data needed by
OAR on t-butyl formate (TBF), which is a possible breakdown product
of MTBE.
II. CHEMICALS REMOVED FROM THE MTL
Since formal issuance of the last MTL in 1992, more than 100
chemical substances have been removed from the MTL for a variety of
reasons. The primary reason for removal is that EPA has received, reviewed
and accepted the results of all required or agreed-upon testing. This is the
case for more than 70 chemicals removed from the MTL since 1992. The
list of all of the chemicals removed from the MTL and the rationale for their
removal is found in INDEX II. The following discussion provides a brief
overview of the individual chemicals and chemical categories that have been
removed from the MTL since 1992 because they completed their respective
testing programs.
16
-------
Twenty-one (21) chemicals have completed their testing programs
under TSCA Section 4 Final Rule-Making (FRM), including:
Nine (9) chemicals tested as the result of EPA's TSCA Section 4
Halogenated Dioxins/Furans Test Rule:
1,2-Bis(2,4,6-tribromophenoxy)ethane
Decabromodiphenyl ether
Octabromodiphenyl ether
Pentabromodiphenyl ether
Tetrabromobisphenol A
Tetrabromobisphenol A allyl ether
Tetrabromobisphenol A bis(ethoxylate)
2,4,6-Tribromophenol
3,4',5-Tribromosalicylanilide
Ten (10) chemicals formally designated for testing by the TSCA
Interagency Testing Committee (ITC):
1,2,4-Trichlorobenzene (3rd ITC Report)
Mesityl oxide (4th ITC Report)
o-Phenylenediamine (6th ITC Report)
m-Phenylenediamine (6th ITC Report)
Vinyl fluoride (7th ITC Report)
Vinylidene fluoride (7th ITC Report)
Commercial hexane (16th ITC Report)
17
-------
Tributyl phosphate (18th ITC Report)
Methyl ethyl ketoxime (19th ITC Report)
Isopropanol (20th ITC Report)
Two (2) chemicals (1,1,2,2-tetrachloroethane and 1,3,5^
trimethylbenzene) from EPA's TSCA Section 4 Office of Drinking
Water Test Rule.
Seven (7) chemicals have completed their testing programs under
TSCA Section 4 Enforceable Consent Agreements (EGA), including 6
chemicals that were formally designated by the ITC for testing under
Section 4 of TSCA:
4-Nonylphenol (branched)
1,1,1 -Trichloroethane (2nd ITC Report)
Methyl t-butyl ether (20th ITC Report)
Crotonaldehyde (22nd ITC Report)
Acrylic acid (27th ITC Report)
4-Vinylcyclohexene (27th ITC Report)
Sodium cyanide (27th ITC Report)
Forty-nine (49) chemicals have completed their testing programs as the
result of Voluntary Testing Agreements (VTA) including:
Fifteen (15) acrylates/methacrylates from the TSCA New
Chemicals Program "Chemical Categories"
Thirty-two (32) chemicals from the OECD/SIDS testing program
One (1) chemical (antimony trioxide) from an industry sponsored,
voluntarily conducted epidemiological study; this chemical had
originally been designated for TSCA Section 4 testing in the
ITC's 4th Report).
18
-------
A voluntary industry-sponsored "Total Volatile Organic
Chemicals" (TVOC) emissions testing program has been
completed on carpets; voluntary TVOC emissions testing for
carpet cushions and carpet adhesives is still underway.
All of the data from completed chemical testing programs are referred for
disposition to EPA's TSCA Existing Chemicals Program "Risk Management"
(RM) process (see Appendix I). For information about public participation in
the TSCA Chemical Testing Program (including information concerning public
access to chemical testing data), the reader's attention is directed to Part IV
of this Introduction.
III. FORMAT, HEADINGS AND CODES FOR 1996-1998 MTL
The MTL is reflected in 2 complementary indices. The first index
("INDEX I. MASTER TESTING LIST") is a "master" index of all chemicals and
categories currently on the MTL as well as those chemicals/categories that
have been removed from the MTL since 1992. the second index ("INDEX II.
CHEMICALS REMOVED FROM THE MTL") includes only those chemicals that
have been removed from the MTL since 1992 and provides the rationale for
their removal. All of the chemicals on the MTL indices are ordered by
ascending Chemical Abstract Service (CAS) Registry Numbers. Those
chemicals and categories that do not have CAS Numbers appear at the
beginning of each index. A description of the index columns as they are
ordered from left to right follows.
i
CAS No.: This unique identifier of up to 9 digits is assigned to chemicals by
the Chemical Abstract Service (CAS). CAS Numbers are not available for
several chemical substances (e.g., commercial hexane) nor are they available
for the categories listed on the MTL. As stated above, chemicals lacking
CAS numbers, as well as categories (which have no CAS Numbers), are
found at the beginning of each index.
Chemical Name: The common chemical name used by EPA.
Source: The chemicals/categories on the MTL have been recommended for
testing by sources from within EPA, other Federal agencies, the TSCA
Interagency Testing Committee (ITC), and the international toxics
community. For a number of chemical substances, there are several sources
of the testing recommendations identified. All of the sources are listed
separately in each of the MTL indices and include the following:
- 19
-------
ATSDR - U.S. Agency for Toxic Substances and Disease Registry
CPSC - U.S. Consumer Product Safety Commission
DOI - U.S. Department of the Interior
ITC - TSCA Interagency Testing Committee (ITC). The ITC was
created under section 4 of TSCA and is mandated to recommend
chemical substances to EPA for testing consideratino. The ITC
recommends these chemicals in twice-yearly formal reports to the EPA
Administrator. This code also indicates the ITC Report number in .
which the chemical was designated for testing. For example, the
source code "ITC/16" indicates that the subject chemical substance
was designated for testing consideration in the ITC's 16th Report to
the EPA Administrator.
OAR - Office of Air and Radiation, US EPA
v
HAP - Hazardous Air Pollutants
OFA - Oxygenated Fuel Additives
OECD - Organization for Economic Cooperation and Development.
OECD member nations have agreed that certain international high
production volume chemicals should have a "base set" of screening
level test data. This base set is referred to as the Screening
Information Data Set (SIDS).
Country: This column identifies the OECD member country or
countries sponsoring the international high production volume
chemicals that have been selected for SIDS testing. Under this
voluntary program, the sponsor first prepares a data summary or
"Dossier" and then conducts testing designed to provide the missing
SIDS data. Countries handling the chemicals are identified by 2-letter
codes. These codes and their corresponding countries are listed in
Table 1. For those chemicals being handled under the European
Union's testing program, the code "EU" appears. For those chemicals
selected for Post-SIDS testing, the acronym "BIAC" appears in place of
the sponsoring country and refers to the OECD's "Business and
Industry Advisory Committee."
20
-------
Table 1. OECD and EU Countries and Codes
OECO
COUNfRY
Australia
Austria*
Belgium*
Canada
Switzerland
Germany*
Denmark*
Finland*
France*
Italy* ,
Japan
Netherlands*
Norway
Spam*
Sweden*
United Kingdom*
United 'States
*European Union Members
Other
EU Member Countries.
Greece
Ireland
Luxembourg
Portugal
COUNTRY
COPE
AU
AT
BE
CA
, CH
DE
DK'
FI
FR
IT
JP
NL
NO '
SP
SE
UK
US
EU
OPPT - Office of Pollution Prevention and Toxics, USEPA. OPPT has
identified existing chemical substances and categories of chemicals in
need of testing through its TSCA Existing Chemicals Program and also
via its TSCA New Chemicals Program. Those chemicals and categories
of chemicals of specific interest to OPPT are found in the following
testing actions that are listed on the MTL:
21
-------
o Aniline/Substituted Anilines (ASA)
o Carpet/Carpet Products (CCP)
o Dioxins/Eurans in Organic Chemicals Rule (DF-OC);
o Dioxins/Furans in Pulp and Paper Mill Sludge (DF-PPMS);
o Endocrine .Disrupters (ED)
o Formaldehyde (F)
o interior Architectural Coatings (!AC)
o Machining Fluids (MF)
o Nleurotoxicity Endpoint Rule (N);
o New Chemicals Program (NCR) "Chemical Categories"
o Chlorofluorocarbon Substitutes (CFCS)
o Fluorescent Whitening Agents (FWA)
o Acrvlates (ACR)
o Vinyl Esters (VE)
o Peroxides (PEROX)
o Nonyl Phenol (NP)
o Paint Strippers (PS) - DiBasic Esters (DBE)
o Persistent Bioaccumulators (PBA) ^
o Reproductive/Developmental (RD) Toxicity Endpoint Rule;
o Respirable Fibers (RF)
\
o Siloxanes (SILOX)
22
-------
o Toxic Release Inventory (TRI) Chemicals
OW - Office of Water, USEPA.
o Office of Drinking Water (ODW) Chemicals
Year Added or Removed: The year in which a chemical substance or
category was added to or removed from the MTL.
Status: One of the following program status codes accompanies each of the
chemicals or categories listed on the MTL:
TNDU: Testing Needs Development Underway - indicates that EPA is in
the process of determining the testing needs for a given chemical or
chemicals within a listed category. Upon identification of specific
testing needs, EPA initiates development of a testing action for the
subject chemical(s) or category as described in the following
paragraph.
' \
TADU: Testing Action Development Underway - indicates that EPA is
initiating development of a testing action via TSCA Section 4 Final
Rule-Making (FRM), a TSCA Section 4 Enforceable Consent Agreement
(EGA), or a Voluntary Testing Agreement (VTA).
CTPU: Chemical Testing Program Underway - CTPU indicates that the
chemical testing program is currently underway by way of an FRM,
EGA, or VTA.
>»
Removed: Removed from MTL - "Removed" indicates that the subject
, chemical substance or category has been deleted from the MTL and
the year of the removal. If Index I. indicates that a chemical or
category has been removed from the MTL, Index II. (which is a list of
, those chemicals or categories removed from the MTL since 1992)
should be consulted for the specific rationale for that removal. The
rationale and additional comments regarding the subject chemical
appear in the far right columns in Index II.
Testing Needs: The last 3 columns of Index I. indicate specific testing needs
for health effects (Health), environmental effects (Environ) and environmental
fate/exposure (Fate). Table 2. below lists the codes for specific testing
needs for the individual chemicals and categories listed on the MTL.
23
-------
Table 2. Testing Need Codes
Health Effects
ACUTE
CARC
CHR
DEVEL
DNEURO
EPID
IMMUN
MUTA
NEURO
PK
PCHR
REPRO
SCHR
SIDS
OTHR
Acute toxicity
Carcinogenicity
Chronic Toxicity
Developmental Toxicity
Developmental Neurotoxicity
Epidemiology
Immunotoxicity
Mutagemcity
s
Neurotoxicity
Pharmocokmetics
Prechronic Toxicity/ 14-28 day
Reproductive Toxicity
Subchronic Toxicity/90 day
Screening Data
Skin Absorption Rate
Other
Environmental Effects
ACUTE
CHR
SIDS
OTHR
"
Acute toxicity
Chronic toxicity
Screening Data
Other
,
Environmental Fate
BIOC
DEGR
MONIT
PCHM
TSPT
SIDS
OTHR
Bioconcentration
Biodegradation
, Monitoring
Physical Chemical Property
Transport/Transformation
Screening Data
Exposure Monitoring
Product Analysis
Other
24
-------
IV. PARTICIPATING IN EPA'S CHEMICAL TESTING PROGRAM
How to Submit Information and Comments
Comments/suggestions for future versions of the MTL should be submitted in
triplicate to EPA's TSCA Public Docket (7407), Attn: TSCA Section 4 Master
Testing List (OPPTS-00200), Office of Pollution Prevention and Toxics, U.S.
Environmental Protection Agency, 401 M Street S.W., Washington, D.C.
20460. Comments that are sent via electronic mail to EPA's TSCA Non-
Confidential Information Center (NCIC) should include reference to the TSCA
Section 4 MTL (OPPTS-00200) and be sent to:
ncic@epamail.epa.gov
Electronic comments and data must be submitted as an ASCII file avoiding
the use of special characters and any form of encryption. Comments and
data will also be accepted on disks in WordPerfect 5.1 file format or ASCII
file format. No TSCA Confidential Business Information (CBI) should be
submitted electronically. Electronic comments concerning the MTL may be
filed online at many Federal Depository Libraries.
How to Obtain Additional Information
a
For further information regarding the MTL or EPA's TSCA Chemical Testing
Program, contact Ms. Susan B. Hazen, Director, Environmental Assistance
Division (7408), Office of Pollution Prevention and Toxics, U.S.
Environmental Protection Agency, 401 M Street S.W., Washington, D.C.
20460, or call the TSCA Hotline at (202) 554-1404, TDD (202) 554-0557.
The TSCA Hotline can also be contacted by using the following electronic
mail (e-mail) address:
TSCA-Hotline@epamail.epa.gov
Further information about the TSCA Existing Chemical Testing and
Information Gathering Programs can also be obtained from EPA's World Wide
Web/Internet site by using the following Uniform Resource Locator (URL):
http://www.epa.gov/opptintr/main/ctibhome.htm
25 ,
-------
EPA is making test results and the results of the Agency's review of test
data available to the public through summaries that are added to TSCATS
(TSCA Test Submissions), a publicly accessible computerized data base. In
addition, information about testing decisions resulting from Risk Management
(RM) meetings are contained in the administrative record, a central collection
point established by OPPT for materials on each chemical handled by OPPT's
Existing Chemical Program. Contents of the administrative record include the
following items:
o a screening dossier containing relevant exposure and hazard
information, recommendations from the screening work group,
and the supporting rationale for that decision;.
o summaries of major studies cited in the screening dossier;
o summaries of RM meetings;
o any letters of concern sent by EPA to industry or others and replies
received by the Agency; and
o comments or correspondence received from other interested parties
outside EPA.
The public can access OPPT's public docket and administrative record in -
person, by going to Room B-607 of the Northeast Mall, EPA Headquarters,
located at 401 M Street SW, Washington, D.C. from 12:00 Noon to 4:00
PM, Monday-Friday except Jegal holidays (photocopy facilities are available),
or by writing to the TSCA Public Docket (7407), Attention: TSCA Existing
Chemicals Program RM Process, Office of Pollution Prevention and Toxics,
U.S. Environmental Protection Agency, 401 M Street S.W., Washington,
D.C. 20460.
26
-------
APPENDIX I. ERA'S EXISTING CHEMICALS PROGRAM: AN OVERVIEW
The U.S. Environmental Protection Agency's (EPA) Existing Chemicals
Program gathers hazard and exposure data, screens for hazards/risks,
identifies testing needs and establishes testing requirements. The Program
also evaluates and develops strategies for preventing pollution and reducing
the risks associated with chemicals currently in production or use in the U.S.
OPPT's risk management and pollution prevention initiatives can be either
regulatory or non-regulatory; all, however, are aimed at reducing or
eliminating the likelihood of harm to health and the environment. The
Chemical Testing Program is a major component of the Existing Chemicals
Program.
Risk management activities in the Existing Chemicals Program are divided
into RM1,RM2 and Post-RM2 stages. Risk Management 1 (RM1) is the first
stage and is designed to screen and select chemicals that appear to be of
greatest concern to human health and the environment and takes about 6
months; identification of additional testing needs is a possible RM1 outcome.
Risk Management 2 (RM2) is the next step, and takes 1 2 to 24 months. At
the RM2 stage of the process, chemicals identified in RM1 are investigated
and analyzed, and options which may include identification of additional
testing needs are framed for reducing or eliminating the risks those chemicals
pose. Post-RM2, which can range between 3 months and 2 years, .consists
of the implementation of one or more of the risk reduction arid/or testing
options identified during RM2.
f
While the Existing Chemicals Program is located in the Chemical Control
Division (CCD) of the Office of Pollution Prevention and Toxics (OPPT),
contributions to the Program come from all parts of OPPT. This collaborative
approach allows pursuit of a wide array of cases. The Existing Chemicals
Program currently draws most of its cases from about 15,000 non-polymeric
chemicals produced or imported at more than 10,000 pounds per year. The
remaining 55,000 of the 70,000 existing chemicals listed on the TSCA
Chemical Substances Inventory are either produced or imported at less than
10,000 pounds per year, if at all, or are'polymers, which because of their
chemical properties, are not considered likely to present a significant risk of
injury to health or the environment. Between 1993 and 1996, the Existing
Chemicals Program has screened approximately 2000 chemicals in RM1.
27
-------
There are many ways in which government, industry and other stakeholders
can work together to meet the nation's environmental goals. In the past,
EPA has relied heavily on regulation to accomplish these goals. We are now '
recognizing that more cooperative methods are often more efficient and
effective. Although regulation under TSCA is still a viable tool and is used
when necessary, the Existing Chemicals Program is increasingly turning to
cooperative and voluntary methods as first approaches to reducing or
eliminating the likelihood of harm to human health and the environment. For
further information'about OPPT's Existing. Chemicals Program in general or
the Chemical Testing Program specifically, interested persons should contact
the TSCA Hotline at (202) 554-1404, TDD (202) 554-0557. EPA's TSCA
Hotline can also be reached at the following electronic mail (e-mail) address:
TSCA-Hotline@epamail.epa.gov
A schematic diagram of OPPT's TSCA Existing Chemicals Program (including
the Chemical Testing Program) operations is provided in Figure 2.
28
-------
OPPT EXISTING CHEMICAL PROGRAM
COMPLETED TESTING
VO
-------
INDEX I. MASTER TESTING LIST
Page 1
CAS
Number
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE .
NONE
NONE
Chemical Name
Beryllium compounds
Carpet Cushions-TVOC
Carpet/Carpet Products
Carpet Adhesives-TVOC
Carpet-TVOC
Chromium compounds
Clean Air Act Section
1 1 2 Chemicals
Commercial hexane
^
Dioxins, polyhalogenated
dibenzo-p-
Dioxins, polyhalogenated
dibenzo-p-
Endocrine Disrupters
Furans, polyhalogenated
dibenzo-
Source
ATSDR
OPPT/CCP
OPPT/CCP
OPPT/CCP
OPPT/CCP
ATSDR
OAR/HAP
ITC/16
OPPT/DF-PPMS
OPPT/DF-OC
OPPT/ED
OPPT/DF-OC
Year
Added
1994
1992
1992
1992
1992
1994
1992
1990
1994
1990
1994
1990
Status
TNDU
CTPU-VTA
CTPU-VTA
CTPU-VTA .
Removed-1996 -
TNDU
TADU
Removed- 1993
CTPU-VTA '
CTPU-FRM
TNDU
CTPU-FRM
Health Effects
PK; ACUTE; SCHR;
REPRO; DEVEL;
IMMUN
I
ACUTE; NEURO;
REPRO; IMMUN
CARC; DEVEL;
MUTA; NEURO; PK;
REPRO; SCHR
Eco Effects
Chemical
Fate
TSPT
Exposure
Monitoring
Exposure
Monitoring
Exposure
Monitoring
Exposure
Monitoring
Exposure
Monitoring
Product
Analysis
Product
Analysis
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 2
CAS
Number
NONE
V.
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
50-00-0
50-81-7
57-10-3
57-13-6
Chemical Name
Furans, polyhalogenated
dibenzo-
Interior Architectural
Coatings
Machining Fluid
Products/Chemicals
Mercury compounds
Oxygenated Fuel
Additives
f\
Paint Stripping
Products/Formulations
Persistent
Bioaccumulators
Respirable Fibers
SARA Section 104
Chemicals (Organics)
SARA Section 1 04
Chemicals (Metals)
Formaldehyde
L-Ascorbic acid
Hexadecanoic acid
Urea
Source
OPPT/DF-PPMS
OPPT/IAC
OPPT/MF
ATSDR
OAR/OFA
OPPT/PS
OPPT/PBA
OPPT/RF
ATSDR
ATSDR
OPPT/F
OECD/SIDS/UK
OPPT/RD
OECD/SIDS/FI
Year
Added
1994
1992
1994
1994
1994
1993
1995
1992
1994
1994
1992
1992
1991
1992
Status
CTPU-VTA
TNDU
TNDU'
TNDU
TADU
CTPU-VTA
TNDU
TNDU
TADU
TNDU
CTPU-VTA
Removed-1996
TADU
Removed-1996
Health Effects
IMMUN; CHR
SIDS
DEVEL
SIDS
Eco Effects
SIDS
SIDS
Chemical
Fate
Exposure
Monitoring
PCHEM
-
Emissions
Testing
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 3
CAS
Number
59-67-6
60-00-4
60:29-7
60-29-7
61-82-5
62-53-3
62-53-3
64-02-8
67-63-0
67-63-0
67-64-1
67-64-1
67-64-1
67-64-1
67-66-3
68-12-2
Chemical Name
Pyridinecarboxylic acid, 3-
Ethylenediaminetetra-
acetic acid
Diethyl ether
Diethyl ether
Amitrole
Aniline
Aniline
Ethylenediaminetetra-
acetic acid, tetrasodium
salt
.Isopropanol
Isopropanol
Acetone
Acetone
Acetone
Acetone
Chloroform
N,N-Dimethylformamide
Source
OECD/SIDS/CH
OECD/SIDS/EU
ITC/31
OPPT/N
ITC/32
OPPT/ASA
OECD/SIDS/EU
OECD/SIDS/EU
ITC/20
OECD/SIDS/US
ITC/28
OPPT/N
OPPT/TRI
OECD/SIDS/US
OECD/SIDS/EU
OECD/SIDS/AU
Year
Added
1990
1994
1993
1991
1993
1995
1994
1994
1990
1994
1992
1991
1993
1994
1995
1995
Status
Removed- 1996
CTPU-VTA
TADU
Removed-1995
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
Removed-1994
CTPU-VTA
TADU
CTPU-ECA
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
Health Effects
SIDS
SIDS
Skin Absorption Rate
NEURO'
Skin Absorption Rate
MUTA
SIDS
SIDS
CARC; MUTA; SCHR;
PK; DEVEL; REPRO;
NEURO
SIDS
REPRO
NEURO
SIDS
SIDS
SIDS
SIDS
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
-
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 4
CAS
Number
70-55-3
71-23-8
71-36-3
71-36-3
71-36-3
71-43-2
71-43-2
71-55-6
74-85-1
74-87-3
74-90-8
74-96-4
74-97-5
75-00-3
75-00-3
75-01-4
Chemical Name
Benzenesulfonamide, 4-
methyl-
Propanol, 1-
Butanol, 1-
Butanol, 1-
Butanol, 1-
Benzene
Benzene
Trichloroethane, 1,1,1-
Ethylene
Chloromethane
Hydrogen cyanide
Ethyl bromide
Bromochloromethane
Chloroethane
Chloroethane
Vinyl chloride
Source
OECD/SIDS/JP
OECD/SIDS/EU
OPPT/N
OECD/SIDS/US
ITC/28
ATSDR
OECD/SIDS/EU
ITC/2
OECD/SIDS/NO
OW/ODW
ATSDR
ITC/32
OPPT/RD
ATSDR
OW/ODW
ATSDR
Year
Added
1990
1995
1991
1994
1992
1994
1994
1990
1992
1990
1994
1993
1991
1994
1990
1994
Status
Removed- 1996
CTPU-VTA
Removed-1995
CTPU-VTA
Removed- 1993
TADU
CTPU-VTA
Removed- 1993
CTPU-VTA
Removed- 1993
TADU
TADU
TADU
TADU
Removed- 1996
Removed-1996
Health Effects
SIDS
SIDS
NEURO
SIDS
REPRO
SCHR;-NEURO;
REPRO
SIDS
DNEURO; NEURO;
MUTA
SIDS
PCHR; SCHR
ACUTE; SCHR;
DEVEL; NEURO
Skin Absorption Rate
REPRO
PK
PCHR; SCHR
DEVEL; REPRO;
NEURO
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
SIDS
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making ,
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page5
CAS
Number
75-02-5
75-05-8
75-05-8
75-09-2
75-12-7
75-15-0
75-15-0
75-25-2
75-34-3
75-34-3
75-35-4
75-35-4
75-38-7
75-45-6
75-54-7
75-56-9
75-65-0
75-69-4
Chemical Name
Vinyl fluoride
Acetonitnle
" Acetonitrile
Methylene chloride'
Formamide
Carbon disulfide
Carbon disulfide -
Bromoform
1 , 1 -Dichloroethane
1 , 1 -Dichloroethane
Vinylidene chloride
Vinylidene chloride
Vinylidene fluoride
Chlorodifluoromethane
Silane, dichloromethyl-
Propylene oxide
t-Butyl alcohol
Fluorotrichloromethane
Source
ITC/7
OECD/SIDS/EU
ITC/35
ATSDR
ITC/35
ITC/32
OPPT/RD
ITC/32
OW/ODW
ITC/32
ITC/35
OAR/HAP
ITC/7
OECD/SIDS/EU
OECD/SIDS/FR
OECD/SIDS/EU
ITC/31
OW/ODW
Year
Added
1990 ,
1994
1994
1994
1994
1993
1 991
1993
1990
1993
1994
1995
1990
1995
1990
1995
1993
1990
Status
Removed-1993
CTPU-VTA
.TADU
TADU
TADU
TADU
TADU
TADU
Removed- 1995
TADU
TADU
TADU
Removed-1993
CTPU-VTA
CTPU-VTA
CTPU-VTA
TADU
Removed-1993
Health Effects
CARC; MUTA
SIDS
Skin Absorption Rate
NEURO
Skin Absorption Rate
Skin Absorption Rate
REPRO; DEVEL
Skin Absorption Rate
PCHR; SCHR
Skin Absorption Rate
Skin Absorption Rate
ACUTE; NEURO;
CARC; MUTA;
REPRO
SIDS
SIDS
SIDS
Skin Absorption Rate
PCHR; SCHR
Eco Effects
SIDS
*
SIDS
SIDS
SIDS
Chemical
Fate
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 6
CAS
Number
75-77-4
75-78-5
75-79-6
75-86-5
75-91-2
75-95-8
75-98-9
76-03-9
76-22-2
77-73-6 .
.77-73-6
77-78-1
77-78-1
77-99-6
78-33-1
78-40-0
Chemical Name
Silane, chlorotrimethyl-
Silane, dichlorodimethyl-
Silane, trichloromethyl-
Acetone cyanhydrin
Hydroperoxide, 1,1-di-
methylethyl-
Tetrachlorobisphenol A
2,2-Dimethylpropanoic
acid
Trichloroacetic acid
Camphor
Dicyclopentadiene
Dicyclopentadiene
Dimethyl sulfate
Dimethyl sulfate.
Propanediol, 2-ethyl-2-
(hydroxymethyl)-, 1,3-
Phosphate, tris(tert-
butylphenyl)
Triethyl phosphate
Source
OECD/SIDS/US
OECD/SIDS/FR
OECD/SIDS/FR
OECD/SIDS/UK
OECD/PSIDS/BIAC
OPPT/DF-OC
OECD/SIDS/NL
OECD/SIDS/DE
j j
ITC/31
ITC/35
OECD/SIDS/JP
ITC/32
OECD/SIDS/EU
OECD/SIDS/JP
ITC/2
OECD/SIDS/DE
Year
Added
1990
1990
1990
1992
1990
,1990
1992
1992
1993
1994
1994
1993
1995
1990
1992
1990
Status
CTPU-VTA
CTPU-VTA
CTPU-VTA
Removed- 1996
CTPU-VTA
FRM
Removed- 1995
CTPU-VTA
TADU
TADU
CTPU-VTA
TADU
CTPU-VTA
Removed-1996
TADU
CTPU-VTA
Health Effects
SIDS
SIDS
SIDS
SIDS
MUTA
SIDS
SIDS
Skin Absorption Rate
Skin Absorption Rate
SIDS
Skin Absorption Rate
SIDS
SIDS
DEVEL; NEURO;
REPRO
SIDS
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
CHR
SIDS
Chemical
Fate
SIDS
SIDS
SIDS
SIDS
DEGR
Product,
Analysis
SIDS
SIDS
SIDS
SIDS
SIDS
DEGR
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 7
.CAS
Number
78-59-1
78-67-1
78-79-5
78-83-1
78-83-1
78-83-1
78-83-1
78-84-2
78-87-5
78-92-2
78-93-3
78-97-7
79-00-5
79-00-5
79-00-5
79-01-6
Chemical Name
Isophorone
2,2'-Azobis(2-methyl-
propanenitrile)
Isoprene
Isobutyl alcohol
Isobutyt alcohol
"Isobutyl alcohol
Isobutyl alcohol
Propanal, 2-methyl-
Propylene dichloride
sec-Butyl alcohol
Methyl ethyl ketone
Propanenitrile, 2-hydroxy-'
1 ,1 ,2-Trichloroethane
1,1, 2-Trichloroethane
1,1, 2-Trichloroethane
Trichloroethylene
Source
ITC/35
OECD/SIDS/JP
OECD/SIDS/NL'
ITC/28
ITC/35
OPPT/N ~
OECD/SIDS/US
OECD/SIDS/US
ITC/35
ITC/31
OECD/SIDS/US
OECD/SIDS/JP
OAR/HAP
OECD/SIDS/JP
OW/ODW
OECD/SIDS/EU
Year
Added
1994
1995
1994
1992
1994
1991
1994
1990
1994
1993
1992
1992
1995
1994
1990
1994
Status
TADU
CTPU-VTA -
CTPU-VTA
Removed-1993
TADU
CTPU-ECA
CTPU-VTA
CTPU-VTA
TADU
TADU~
CTPU-VTA
Removed-1996
TADU
CT^U-VTA
Removed-1993
CTPU-VTA
Health Effects
Skin Absorption Rate
SIDS
SIDS
CARC; DEVEL; PK;
REPRO
Skin Absorption Rate
NEURO
SIDS
SIDS
Skin Absorption Rate
Skin Absorption Rate
SIDS
SIDS
ACUTE; SCHR;
NEURO; DEVEL;
REPRO; CARC;
MUTA; IMMUN;
SIDS
PCHR; SCHR
,SIDS
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
PageS
CAS
Number
79-01-6
79-06-1
79-10-7
79-10-7
79-11-8
79-20-9
79-20-9
79-31-2
79-34-5
79-41-4
79-46-9
79-92-5
79-94-7
79-94-7
79-94-7
80-05-7
80-15-9
Chemical Name
Trichloroethylene
Acrylamide
Acrylic acid
Acrylic acid
Chloroacetic acid
Methyl acetate
Methyl acetate
Methylpropanoic acid, 2-
Tetrachloroethane,
1,1,2,2-
Methacrylic acid
2-Nitropropane
Camphene
Tetrabromobisphenol A
Tetrabromobisphenol A
Tetrabromobisphenol A
Bisphenol.A
Cumene hydroperoxide
Source
ATSDR
OECD/SIDS/EU
ITC/27-
OECD/SIDS/EU
OECD/SIDS/SE
ITC/31
OECD/SIDS/EU
OPPT/RD
OW/ODW
OECD/SIDS/EU
ITC/32
OECD/SIDS/DE
OPPT/DF-OC
OECD/SIDS/US
OPPT/DF-OC
OECD/SIDS/CH
OPPT/NCP/PEROX
Year
Added
1994
1994
1992
1994
1992
1993
1994
1991
1990
1994
1993
1990
1990
1992
1990
1992
1996
1
Status
TADU
CTPU-VTA
Removed- 1-994
CTPU-VTA
CTPU-VTA
TADU
CTPU-VTA
TADU
Removed-1996
CTPU-VTA
TADU
Removed-1996
FRM - .
Removed-1994
Removed-1 994
CTPU-VTA
CTPU-VTA
Health Effects
SCHR; IMMUN
SIDS
DEVEL;.PK; REPRO
SIDS
SIDS
Skin Absorption Rate
SIDS
DEVEL
PCHR; SCHR
SIDS -
Skin Absorption Rate
SIDS
SIDS
SIDS
Other
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
-
SIDS
SIDS
Chemical
Fate
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
Product
Analysis
SIDS
Product
Analysis
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 9
CAS
Number
80-43-3
80-43-3
80-62-6
80-62-6
80-62-6
81-11-8
82-45-1
84-66-2
84-74-2 ' .
85-44-9
87-10-5
87-10-5
87-65-0
87-90-1
Chemical Name
Dicumyl peroxide
Dicumyl peroxide
Methyl methacrylate
Methyl methacrylate
Methyl methacrylate
Benzenesulfonic acid;
2,2'-(1,2-ethenedi-
1 -Aminoanthraquinone
Diethyl phthalate
Dibutyl phthalate
Phthalic anhydride
Tribromosalicylanilide,
3,4', 5-
Tribromosalicylanilide,
3,4',5-
2,6-Dichlorophenol
Trichloro-S-triazinetrione
Source
OPPT/NCP/PEROX
OECD/SIDS/BE
OAR/HAP
OECD/SIDS/EU
ITC/32
OECD/SIDS/JP-
OECD/SIDS/JP
ITC/32
OECD/SIDS/EU
OAR/HAP
OPPT/DF-OC
OPPT/DF-OC
OPPT/DF-OC
OECD/SIDS/JP
Year
Added
1996
1992
1995
,1994
1993
1992
1992
1993
1994
1995
1990
1990
1990
1994
Status
CTPU-VTA
Removed-1994
TADU
CTPU-VTA
Removed-1994
CTPU-VTA
CTPU-VTA
Removed-1994
CTPU-VTA
TADU
FRM
Removed-1992
FRM
CTPU-VTA
Health Effects
Other
SIDS
ACUTE; NEURO;
. DEVEL; REPRO;
IMMUN;
SIDS
Skin Absorption Rate
SIDS
SIDS
Skin Absorption Rate
SIDS
ACUTE; SCHR;
NEURO; DEVEL;
REPRO; CARC;
IMMUN;
SIDS
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
_
SIDS
Chemical
, Fate
'-
SIDS
SIDS
SIDS ---
SIDS
SIDS
Product
Analysis
Product
Analysis
Product
Analysis
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 10
CAS
Number
88-12-0
88-72-2
88-72-2
89-61-2
89-72-5
89-83-8
90-02-8
90-04-0
90-04-0
91-20-3
91-20-3
91-20-3
92-52-4
92-52-4
92-70-6
Chemical Name
N-Vinyl pyrrolidone
o-Nitrotoluene
o-Nitrotoluene
Benzene, 1,4-dichloro-2-
nitro-
o-sec-Butylphenol
Thymol
o-Hydroxybenzaldehyde
o-Anisidine
o-Anisidine
Naphthalene
Naphthalene
Naphthalene
Biphenyl
Biphenyl
2-Hydroxy-3-naphthoic
acid
Source
OECD/SIDS/EU + AU
OECD/SIDS/SE
ITC/32
OECD/SIDS/JP
ITC/32
OECD/SIDS/JP
OECD/SIDS/JP
OECD/SIDS/EU
ITC/32
OAR/HAP
OECD/SIDS/EU
ITC/35
OAR/HAP
ITC/35
OECD/SIDS/DE
Year
Added
1995
1990
1993
1992
1993
1994
1994
1995
1993
1995
1994 -
1994
1995
1994
1992
Status
CTPU-VTA
CTPU-VTA
TADU
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
TADU
TADU
CTPU-VTA
TADU
TADU
TADU
CTPU-VTA
Health Effects
SIDS
SIDS
Skin Absorption Rate
SIDS
Skin Absorption Rate
SIDS
SIDS
SIDS
Skin Absorption Rate
ACUTE; REPRO;
IMMUN;
SIDS
Skin Absorption Rate
ACUTE; SCHR;
NEURO; DEVEL;
REPRO; IMMUN;
Skin Absorption Rate
SIDS
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
j
SIDS
Chemical
Fate
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
'SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
11
CAS
Number
94-04-2
94-36-0
95-13-6
95-31-8
95-33-0
95-48-7
95-48-7
95-49-8
95-50-1
95-54-5
95-73-8
95-76-1
95-77-2
95-80-7
95-80-7
Chemical Name
Vinyl 2-ethylhexanoate
Dibenzoyl peroxide
Indene
N-tert-Butyl-2-benzo-
thiazosulfenamide
N-Cyclohexyl-2-benzo-
thiazosulfenamide
o-Cresol
o-Cresol
o-Chlorotoluene
1 ,2-Dichlorobenzene
Phenylenediamine, ortho-
2,4-Dichlorotoluene
3,4-Dichloroaniline
3,4-Dichloroph.enol
2,4-Toluenediamine
2,4-Toluenediamine
Source
OPPT/NCP/VE
OPPT/NCP/PEROX -
ITC/32
OECD/SIDS/JP
OECD/SIDS/EU + JP
OECD/PSIDS/BIAC
OAR/HAP
ITC/32
ITC/35
ITC/6
OECD/SIDS/JP
OECD/SIDS/EU
OPPT/DF-OC
OECD/SIDS/EU
OPPT/RD .
Year
Added
1993
1996
1993
1995
1995
1992
1995
1993
1994
1990
1992
1994
1990
1994
1991
Status
CTPU-ECA
*
CTPU-VTA
TADU'
CTPU-VTA
CTPU-VTA
CTPU-VTA
TADU
TADU
TADU
Removed- 1993
CTPU-VTA
CTPU-VTA
FRM
CTPU-VTA
TADU
Health Effects
SCHR; NEURO;
DEVEL; REPRO;
CARC
Other
Skin Absorption Rate
SIDS -
SIDS
SCHR
ACUTE; SCHR;
NEURO; IMMUN;
Skin Absorption Rate
Skin Absorption Rate
NEURO
SIDS
SIDS
SIDS
DEVEL; REPRO
Eco Effects
-
SIDS
SIDS .
CHR
ACUTE; CHR
SIDS
SIDS
.-
SIDS
Chemical
Fate
SIDS
SIDS
"
TSPT
SIDS
SIDS
Product
Analysis
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway-
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 12
CAS
Number
95-95-4-
96-18-4
96-29-7
97-65-4
97-77-8
98-01-1
98-08-8
98-29-3
98-54-4
98-56-6
98-82-8
98-83-9
98-86-2
99-08-1
99-09-2
Chemical Name
2,4,5-Trichlorophenol
1 ,2,3-Trichloropropane
Methyl ethyl ketoxime
Butanedioic acid,
methylene-
Disulfiram
2-Furaldehyde
(Trifluoromethyl) benzene
t-Butyl catechol
p-t-Butyl phenol
Benzene, 1-chloro-4-
(trifluoromethyl)-
Cumene
(1 -MethylethenyDbenzene
Acetophenone
m-Nitrotoluene
Nitroaniline, 3-
Source
OPPT/DF-OC
ITC/35
ITC/19
OECD/SIDS/FR
ITC/31
OECD/SIDS/EU
OECD/SIDS/JP
ITC/35
OECD/SIDS/JP
OECD/SIDS/IT + US
OECD/SIDS/EU + US
OECD/SIDS/JP
ITC/27
ITC/35
OECD/SIDS/JP
Year
Added
1990
1994
1990
1992
1993
1995
1994
1994
1994
1992
1994
1994
1992
1994
1990
Status
FRM
TADU
Removed- 1994
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
TADU
TADU
CTPU-VTA
Health Effects
Skin Absorption Rate
CARC; NEURO;
DEVEL; REPRO;
MUTA
SIDS
Skin Absorption Rate
SIDS
SIDS
Skin Absorption Rate
SIDS
SIDS
SIDS
SIDS
DEVEL; MUTA;
NEURO; PK; REPRO;
SCHR
Skin Absorption Rate
SIDS
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
Product
Analysis '
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
"Page 13
CAS
Number
99-28-5
99-65-0
99-96-7
99-99-0
100-00-5
100-01-6
100-21-0
100-21-0
100-25-4
1 00-40-3
100-41-4
100-41-4
100-41-4
100-42-5
100-42-5
100-44-7
100-44-7
Chemical Name
2,6-Dibromo-4-nitro-
phenol
m-Dinitrobenzene
4-Hydroxybenzoic acid
p-Nitrotoluene
p-Nitrochlorobenzene
p-Nitroaniline
Terephthalic acid
Terephthalic acid
p-Dinitrobenzene
Vinylcyclohexene, 4-
Ethylbenzene
Ethylbenzene
Ethylbenzene
Styrene
Styrene
/
Benzyl chloride
Benzyl chloride
Source
OPPT/DF-OC
ITC/32
OECD/SIDS/JP
ITC/35
ITC/32
ITC/32
OPPT/RD
OECD/SIDS/IT
ITC/31
ITC/27
OPPT/TRI
OAR/HAP
OECD/SIDS/EU + US
OPPT/TRJ
OECD/SIDS/EU + US
OECD/SIDS/JP
ITC/32
Year
Added
1990
1993
1995
1994
1993
1993
1991
1992
1993
1992
1993 ,
1995
1994
1993
1994
1994
1993
Status
FRM
TADU
CTPU-VTA
TADU
TADU
TADU
TADU
CTPU-VTA
TADU
Removed-1995
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
TADU
Health Effects
Skin Absorption Rate'
SIDS
Skin Absorption Rate
Skin Absorption Rate
Skin Absorption Rate
REPRO
SIDS
Skin Absorption Rate
MUTA; PK; SCHR
SIDS
ACUTE; NEURO;
DEVEL; REPRO;
IMMUN;
SIDS
SIDS
SIDS
SIDS
Skin Absorption Rate
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
Product
Analysis
SIDS
SIDS
TSPT
SIDS
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 14
CAS
Number
100-52-7
100-63-0
100-97-0
101-54-2
101-68-8
101-72-4
101-77-9
101-90-6
102-01-2
102-71-6
103-11-7
103-23-1
103-23-1
103-65-1
104-76-7
Chemical Name
Benzaldehyde
Phenylhydrazine
1,3,5,7-Tetraazatri-
cyclo(3.3.1)decane
1,4-Benzenediamine, N-
phenyl-
Methylenediphenyl
diisocyanate, 4,4'-
Benzenediamine, N-(1-
methylethyl)-N'-phenyl-,
1,4-
4,4'-Methylenebisaniline
Resorcinol diglycidyl ether
Acetoacetanilide
Triethanolamine
2-Ethylhexyl acrylate
Di(2-ethylhexyl)adipate
Di(2-ethylhexyl)adipate
Propylbenzene, n-
Ethylhexanol, 2-
Source
OECD/SIDS/NL
ITC/32
OECD/SIDS/EU
OECD/SIDS/DE
OECD/SIDS/US
OECD/SIDS/UK
OECD/SIDS/EU
ITC/3
OECD/SIDS/US
OECD/SIDS/UK
OECD/SIDS/EU
OECD/SIDS/US
ITC/28
OW/ODW
OECD/SIDS/SE
Year
Added
1992
1993
1995
1992
1992
1990
1994
1992
1992
1992
1994
1994
1992
1990
1992
Status
Removed- 1996
TADU
CTPU-VTA
Removed-1994
CTPU-VTA
CTPU-VTA
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
Removed-1993
Removed-1993
CTPU-VTA
Health Effects
SIDS
Skin Absorption Rate
SIDS
SIDS
SIDS ~
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
DEVEL; NEURO;
REPRO
PCHR; SCHR
SIDS
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
CHR
SIDS
Chemical
Fate
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
DEGR;
PCHM
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
15
CAS
Number
104-76-7
104-90-5
104-94-9
105-05-5
105-46-4
1 05-76-0
105-99-7
106-42-3
106-42-3
106-44-5
106-44-5
106-46-7
106-46-7 x
106-49-0
106-50-3
106-65-0
106-90-1
Chemical Name
Ethylhexanol, 2-
2-Picoline, 5-ethyl-
Aniline, 4-methoxy-
Benzene, 1,4-diethyl-
sec-Butyl acetate
Maleic acid, dibutyl ester
Di-butyl adipate
p-Xylene
p-Xylene
p-Cresol
p-Cresol
1 ,4-Dichlorobenzene
1 ,4-.Dichlorobenzene
p-Toluidine
Phenylenediamine, para-
Dimethyl succinate
Glycidyl acrylate
Source
OPPT/RD,
OECD/SIDS/CH
OECD/SIDS/DE
OECD/SIDS/JP
ITC/31
OECD/SIDS/AT
OECD/SIDS/JP _ :,-_
OECD/SIDS/IT
ITC/31
OAR/HAP
OECD/SIDS/US
OECD/SIDS/EU
ITC/35
ITC/32
ITC/6
OPPT/PS/DBE
ITC/3
Year
Added
1991
1992
1992
1992
1993
1990
1992
1992
1993
1995
1992
1994
1994
1993
1990 -
1994
1992
Status
TADU
CTPU-VTA
Removed- 1994
Removed- 1996
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
(
TADU
TADU
Removed- 1994
CTPU-VTA
TADU
TADU
CTPU-FRM
TADU
TADU
Health Effects
DEVEL
SIDS
SIDS
SIDS
Skin Absorption Rate
SIDS
SIDS
SIDS
Skin Absorption Rate
ACUTE; SCHR;
NEURO; IMMUN;
SIDS
SIDS
Skin Absorption Rate
Skin Absorption Rate
NEURO
PK; MUTA; ACUTE;
NEURO; REPRO;
DEVEL; SCHR;
CARC;
CARC; MUTA; SCHR
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS .
SIDS
SIDS
SIDS
ACUTE; CHR
Chemical
Fate
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
TSPT
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 16
CAS
Number
106-91-2
106-91-2
106-92-3
106-98-9
106-99-0
107-01-7
107-02-8
107-05-1
107-06-2
107-06-2
107-13-1
.107-13-1
107-21-1
107-21-1
107-22-2
107-31-3
Chemical Name
Glycidyl methacrylate
Glycidyl methacrylate
Allyl glycidyl ether
Butene, 1-
1,3-Butadiene
Butene, 2-
Acrolein
3-Chloropropene
Ethylene dichloride
Ethylene dichloride
Acrylonitrile
Acrylonitrile
Ethylene glycol
Ethylene glycol
Glyoxal
Methyl formate
Source
OECD/SIDS/JP + US
ITC/3
ITC/3
OECD/SIDS/CA
OECD/SIDS/EU
OECD/SIDS/NL
OECD/SIDS/EU
OECD/SIDS/NL
OAR/HAP
ITC/3 5
OPPT/RD
OECD/SIDS/EU^
OAR/HAP
OECD/SIDS/CA
OECD/SIDS/FR
ITC/3 1
Year
Added
1995.
1992
1992
1992
1994
1990
1994
1994
1995
1994
1991
1994
1995
1992
1992
1993
Status
CTPU-VTA
CTPU-ECA
TADU
CTPU-VTA
CTPU-VTA
Removed- 1996
CTPU-VTA
CTPU-VTA
TADU
TADU
TADU
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
TADU
Health Effects
SIDS
DEVEL; MUTA; SCHR
DEVEL; MUTA;
NEURO; REPRO;
SCHR
SIDS -
SIDS
SIDS
SIDS -
SIDS
ACUTE; SCHR;
NEURO; DEVEL;
REPRO;
Skin Absorption Rate
DEVEL
SIDS
ACUTE; SCHR;
NEURO; IMMUN;
SIDS
SIDS
Skin Absorption Rate
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 17
CAS
Number
107-46-0
107-64-2
107-66-4
.107-66-4
108-01-0
108-03-2
108-05-4
108-05-4
108-10-1
108-10-1
108-10-1
108-24-7
108-31-6
108-39-4
Chemical Name
Hexamethyldisiloxane
1 -Octadecanaminium;
N,N-dimethyl-N-
octadecyl-, chloride
Dibutyl phosphate
Dibutyl phosphate
Dimethylaminoethanol
1-Nitropropane
Vinyl acetate
Vinyl acetate
Methyl isobutyl ketone
Methyl isobutyl ketone
Methyl isobutyl ketone
Acetic anhydride
Maleic anhydride
m-Cresol
Source
OPPT/SILOX
OECD/SIDS/DE
ITC/31
OECD/SIDS/JP
OECD/SIDS/UK
ITC/31
OPPT/TRI
OECD/SIDS/EU + US
OECD/SIDS/US
OAR/HAP
OPPT/N
OECD/SIDS/CA
OAR/HAP
OAR/HAP
Year
Added
1996
1992
1993
1992
1992
1993
1993
1994
1992
1995
1991
1992
1995
1995
Status
CTPU-VTA
Removed-1996
TADU
Removed-1996
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
TADU
CTPU-ECA
CTPU-VTA
TADU
TADU
Health Effects
PK; PCHR; IMMUN; -
REPRO; DEVEL;
NEURO; SCHR;
CARC
SIDS '
Skin 'Absorption Rate
SIDS
SIDS .
Skin Absorption Rate
SIDS
SIDS
SIDS
ACUTE; REPRO;
IMMUN;
NEURO
SIDS
ACUTE; NEURO;
DEVEL; CARC;
IMMUN;
ACUTE; SCHR;
NEURO; IMMUN;
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
-
-_
SIDS
Chemical
Fate
MONIT
SIDS
SIDS
SIDS
-
SIDS
SIDS
SIDS
.
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable.Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 18
CAS
Number
108-44-1
108-44-1
108-45-2
108-67-8
108-78-1
108-80-5
108-83-8
108-87-2
108^88-3
108-88-3
108-89-4
108-90-7
-108-90-7
108-93-0
108-94-1
108-94-1
108-95-2
Chemical Name
m-Toluidine
m-Toluidine
Phenylenediamine, meta-
Trimethylbenzene, 1,3,5-
Melamine
Isocyanuric acid
Heptanone, 2,6-di-
methyl-, 4-
Methylcyclohexane
Toluene
Toluene
Pyridine, 4-methyl-
Chlorobenzene
Chlorobenzene
Cyclohexanol
Cyclohexanone
Cyclohexanone
Phenol
Source
ITC/32
OECD/SJDS/JP
ITC/6
OW/ODW
OECD/SIDS/AT
OECD/SIDS/JP
OEGD/SIDS/FR
ITC/31
OECD/SIDS/EU
ATSDR
OECD/SIDS/BE
OAR/HAP
ITC/32
ITC/35
ITC/35
OECD/SIDS/CA
ITC/27
Year
Added
1993
1992
1990
1990
1992
1995
1990
1993
1995
1994
1990
1995
1993
1994
1994
1992
1992
Status
TADU
CTPU-VTA
Removed- 1993
Removed-1995
CTPU-VTA
CTPU-VTA
CTPU-VTA
TADU
CTPU-VTA
TADU
Removed- 1994
TADU
TADU
TADU
Removed-1995
Removed-1996
CTPU-ECA
Health Effects
Skin Absorption Rate
SIDS
NEURO; MUTA
PCHR; SCHR
SIDS
SIDS
SIDS
Skin Absorption Rate
SIDS
PK; IMMUN
SIDS
ACUTE; SCHR;
NEURO; IMMUN;
Skin Absorption Rate
Skin Absorption Rate
Skin Absorption Rate
SIDS
NEURO; PK; REPRO;
SCHR
Eco Effects
SIDS
ACUTE; CHR
SIDS
SIDS
SIDS
SIDS
SIDS
\
SIDS
Chemical
Fate
SIDS
TSPT
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS .
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 19
CAS
Number
108-95-2
108-95-2
108-98-5
108-99-6
109-06-8
109-16-0
109-55-7
109-66-0
109-66-0
109-69-3
109-99-9
109-99-9
109-99-9
110-02-1
110-05-4
110-12-3
110-27-0
Chemical Name
Phenol
Phenol
Thiophenol
Pyridine, 3-methyl-
Pyridine; 2-methyl-
Triethylene glycol
dimethacrylate
1 -Amino-3-dimethylamino
propane
Pentane
Pentane
Chlorobutane, 1-
Tetrahydrofuran
Tetrahydrofuran
Tetrahydrofuran
Thiophene
Di-t-butyl peroxide
Methyl isoamyl ketone
Isopropyl myristate
Source
OECD/SIDS/EU
OAR/HAP
ITC/28
OECD/SIDS/BE
OECD/SIDS/BE
OPPT/NCP/ACR
OECD/SIDS/DE ,
ITC/31
OECD/SIDS/EU
OECD/SIDS/JP
OPPT/N
OECD/SIDS/US
ITC/32
OECD/SIDS/JP .
OPPT/NCP/PEROX
ITC/35
OECD/SIDS/DE
Year
Added
-1994
1995
1992
1990
1990
1992
*
1992
1993
1995.
1992
1991
1995
1993
1994
1996
1994
1992
Status
CTPU-VTA
CTPU-ECA
TADU
Removed- 1994
Removed- 1994
Removed- 1995
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
CTRU-ECA
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
TADU
CTPU-VTA
Health Effects
SIDS
ACUTE; IMMUN
CARC; DEVEL;
MUTA; NEURO; PK;
REPRO
SIDS '
SIDS
OTHR; PCHR; SCHR;
CARC;
SIDS
Skin Absorption Rate
SIDS
SIDS
NEURO
SIDS
Skin Absorption Rate
SIDS
Other
Skin Absorption Rate
SIDS
Eco Effects
SIDS
ACUTE; CHR
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
SIDS
DEGR; TSPT;
PCHM
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4.Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 20
CAS
Number
110-30-5
1 1 0-49-6
110-63-4
110-65-6
110-80-5
1 1 0-80-5
110-82-7
110-82-7 -
110-83-8
110-85-0
110-91-8
111-11-5
111-15-9
111-30-8
1 1 1 -40-0
Chemical Name
Octadecanamide, N,N'-
1,2-ethanediylbis-
2-Methoxyethyl acetate
1 ,4-Butanediol
2-Butyne-1,4-diol
Ethoxyethanol, 2-
Ethoxyethanol, 2-
Cyclohexane
Cyclohexane
Cyclohexene
Piperazine
Morpholine
Octanoic acid, methyl
ester
Ethoxyethanol, 2-,
acetate
Gluteraldehyde
Diethylenetriamine
Source
OECD/SIDS/US
OECD/SIDS/EU
OECD/SIDS/JP
OECD/SIDS/EU
OECD/SIDS/EU
OPPT/N
ITC/17
OECD/SIDS/EU
ITC/31
OECD/SIDS/SE
OECD/SIDS/UK
OPPT/RD
OECD/SIDS/EU
OECD/SIDS/AU
OECD/SIDS/NL
Year
Added
1992
1994
1995
1994
1995
1991
1990
1994
1993
1994
1992
1991
1995
1994
1992
Status
Removed- 199 5
Removed-1995
CTPU-VTA
CTPU-VTA
CTPU-VTA
Removed-1995
CTPU-ECA
CTPU-VTA
TADU
CTPU-VTA
Removed-1994
TADU
CTPU-VTA
CTPU-VTA
Removed- 1996
Health Effects
SIDS
SIDS
SIDS
SIDS
SIDS
NEURO
ACUTE; CARC;
DEVEL; MUTA;
NEURO; PK; REPRO;
SCHR
SIDS
Skin Absorption Rate
SIDS
SIDS
DEVEL
SIDS
SIDS
SIDS
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
SIDS
SIDS
SIDS
SIDS'
SIDS
SIDS
SIDS
SIDS
"-
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 21
CAS
Number
111-42-2
111-42-2
111-46-6
111-66-0
111-69-3 ,
111-76-2
111-77-3
111-82-0,
111-84-2
112-18-5
112-24-3
112-34-5
.112-35-6
112-41-4 .
Chemical Name
Diethanolamine
Diethanolamine
Diethylene glycol
1-Octene
1 ,4-Dicyanobutane
Butoxyethanol, 2-
2-(2-Methoxyethoxy)-
ethanol
Dodecanoic acid, methyl
ester
Nonane
N,N-Dimethyldodecyl-
amine -
Triethylene tetramine
2-(2-Butoxyethoxy)-
ethanol
Ethanol, 2-[2-(2-methoxy-
ethoxy) ethoxy]-
1-Dodecene
Source
OECD/PSIDS/BIAC
OAR/HAP
OECD/SIDS/CA
OECD/SIDS/US
OECD/SIDS/FR
OECD/SIDS/AU
OECD/SIDS/EU
OECD/SIDS/JP
ITC/31
OECD/SIDS/DE
OECD/SIDS/DE
OECD/SIDS/EU
OECD/SIDS/US
OECD/SIDS/US
Year
Added
1992
1995
1992
1992
1992
1995
1994
1994
1993
1992
1992
1994
1992
1992
Status
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
Health Effects
SCHR;NEURO;DEVEL
;REPRO
ACUTE; SCHR;
NEURO; DEVEL;
REPRO; IMMUN;
SIDS
SIDS'
SIDS
SIDS
SIDS
SIDS
Skin Absorption Rate
SIDS
SIDS
SIDS
SIDS
SIDS
Eco Effects
-
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
Chemical "
Fate
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 22
CAS
Number
112-50-5
112-53-8
112-72-1
112-90-3
112-92-5
115-11-7
115-18-4
115-19-5
115-77-5
115-86-6
115-95-7
115-96-8
115-96-8
116-15-4
117-81-7
117-84-0
Chemical Name
Triethylene glycol,
monoethyl ether
Dodecanol, 1-
1 -Tetradecanol
9-Octadecen-1 -amine,
(Z)-
Octadecanol, 1-
2-"Methylpropene
3-Buten-2-ol, 2-methyl-
3-Butyn-2-ol, 2-methyl-
Pentaerythritol
Triphenyl phosphate
Dehydrolinalool, acetate
Tris{2-chloroethyl)-
phosphate
Tris(2-chloroethyl)-
phosphate
Hexafluoropropene
Di(2-ethylhexyl)phthalate
Dioctyl phthalate
Source
OECD/SIDS/US
OECD/SIDS/DK
OECD/SIDS/US
OECD/SIDS/US
OECD/SIDS/DK
OECD/SIDS/FR
OECD/SIDS/CH
OECD/SIDS/DE
OECD/SIDS/JP
ITC/2
OECD/SIDS/CH
OECD/SIDS/EU
ITC/23
OECD/SIDS/IT + US
OECD/SIDS/EU
OECD/SIDS/EU
Year
Added
1992
1990
1992
1992
1990
1992
1992
1992
1994
1992
1995
1995
1990
1990
1995
1994
Status
CTPU-VTA
CTPU-VTA
Removed-1 994
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
Removed-1995
CTPU-VTA
CTPU-VTA
Removed-1995
Health Effects
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
DEVEL; NEURO;
REPRO
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
CHR -
SIDS
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS .
DEGR
SIDS
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 23
CAS
Number
118-69-4
118-75-2
118-75-2
118-79-6
118-79-6
120-36-5
120-61-6
120-61-6
120-78-5
120-80-9
120-80-9
120-82-1
120-82-1
120-82-1
Chemical Name
'2,6-Dichlorotoluene
Chloranil
Chloranil
2,4,6-Tribromophenol
2,4,6-Tribromophenol
2[2,4-(Dichlorophenoxy)J-
propionic acid
Dimethyl terephthalate
Dimethyl terephthalate
Benzthiazole disulfide
Catechol
Catechol
1 ,2,4-Trichlorobenzene
1 ,2,4-Trichlorobenzene
1 ,2,4-Trichlorobenzene
Source
OECD/SIDS/JP
OPPT/DF-OC
OPPT/DF-OC
OPPT/DF-OC
OPPT/DF-OC
OPPT/DF-OC
ITC/28
OECD/SIDS/IT
OECD/SIDS/DE
ITC/35
OPPT/RD
ITC/3
OECD/SIDS/EU
OAR/HAP
Year
Added
1992
1990
1990
1990
1990
1990
\
1992
1992
1992
1994
1991
1990
1995
1995
Status
CTPU-VTA
FRM
CTPU-FRM
FRM
"Removed- 1994
FRM
Removed-1993
CTPU-VTA
CTPU-VTA
TADU
TADU
Removed- 1994
CTPU-VTA
TADU
Health Effects
SIDS
;
DEVEL; NEURO;
REPRO
SIDS
SIDS
Skin Absorption Rate
DEVEL
CARC
SIDS
ACUTE; NEURO;
DEVEL; IMMUN;
Eco Effects
SIDS
- ' -
ACUTE; CHR
SIDS
SIDS
-
SIDS
Chemical
Fate
SIDS
Product
Analysis
Product
Analysis
Product
Analysis
Product .
Analysis'
Product
Analysis
DEGR
SIDS
SIDS
'
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
ECA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 24
CAS
Number
120-83-2
121-14-2
121-14-2
121-33-5
121-57-3
121-69-7
121-69-7
121-69-7
122-39-4
122-52-1
122-60-1
123-01-3
123-30-8
123-30-8
123-31-9
123-38-6
123-42-2
123-42-2
Chemical Name
2,4-Dichlorophenol
2,4-Dinitrotoluene
2,4-Dinitrotoluene
Vanillin'
Benzenesulfonic acid, 4-
amino-
Dimethylaniline, N,N-
Dimethylaniline, N,N-
Dimethylaniline, N,N-
Diphenylamine
Triethyl phosphite -
Phenyl glycidyl ether
Dodecylbenzene
Aminophenol, p-
Aminophenol, p-
Hydroquinone
Propanal
Diacetone alcohol
Diacetone alcohol
Source
OPPT/DF-OC
OECD/SIDS/DE
ITC/32
OECD/SIDS/NO
OECD/SIDS/DE
ITC/35
ITC/27
OECD/SIDS/US
ITC/32
OECD/SIDS/DE
ITC/3
OECD/SIDS/US
OPPT/RD
OECD/SIDS/JP
OECD/SIDS/US
OECD/SIDS/US
ITC/35
OECD/SIDS/JP
Year
Added
1990
1992
1993
1992
1990
1994
1992
1995
1993
1990
1992
1992
1991
1995
1992
1990
1994
1995
Status
FRM
CTPU-VTA
TADU
CTPU-VTA
Removed- 19 94
TADU
CTPU-VTA
CTPU-VTA
TADU
Removed-1 994
TADU
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
TADU
CTPU-VTA
Health Effects
SIDS
Skin Absorption Rate
SIDS
SIDS
Skin Absorption Rate
SIDS
SIDS
Skin Absorption Rate
SIDS
NEURO; REPRO
SIDS
DEVEL
SIDS
SIDS
SIDS
Skin Absorption Rate
SIDS
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
Product
Analysis
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS ,
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final .Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 25
CAS
Number
123-72-8
123-77-3
123-86-4
123-86-4
123-91-1
123-92-.2
1 24-09-4
124-18-5
126-30-7
126-58-9
126-73-8
126-80-7
126-99-8
126-99-8
126-99-8
Chemical Name
Butyraldehyde
Diazenedicarboxamide
Butyl acetate, n-
Butyl acetate, n-
1 ,4-Dioxane
Isoamyl acetate
1 ;6-Hexanediamine
n-Decane
Propanediol, 2,2-
dimethyl-, 1,3-
1,3-Propanediol, 2,2'-
[oxybis-(methylene)
Tributyl phosphate
1,3-Bis(3-(2,3-epoxy-
propoxy)propyl]tetra-
methyldisiloxane
Chloroprene
X
Chloroprene
Chloroprene
Source
OECD/SIDS/US
OECD/SIDS/DE
OECD/SIDS/US
OPPT/N
OECD/SIDS/EU +-AU
ITC/31
OECD/SIDS/CA
OECD/SIDS/IT
OECD/SIDS/JP
OECD/SIDS/SE
ITC/18
ITC/3
OAR/HAP
ITC/32
OECD/SIDS/DE
Year
Added
1992
1992
1995
1991
1995
1993
1 992-
1992
1990
1990
1990
1992
1995
1993
1992
Status
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-ECA
CTPU-VTA
TADU
Removed-1996
CTPU-VTA
Removed-1996 "
Removed-1996
Removed-1994
TADU
TADU
TADU
CTPU-VTA
Health Effects
SIDS
SIDS
sibs
NEURO
SIDS
Skin Absorption Rate
SIDS -
SIDS
SIDS
SIDS
CARC; DEVEL;
MUTA; NEURO;
OTHR; PK; REPRO
ACUTE; NEURO;
REPRO; IMMUN;
Skin Absorption Rate
SIDS
Eco Effects
SIDS
SIDS.
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
ACUTE; CHR
-
SIDS
Chemical
Fate
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
PCHM; TSPT
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Actidn Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final .Rule" Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 26
CAS
Number
127-18-4
127-18-4
127-19-5
127-19-5
128-39-2
128-39-2
135-19-3
140-66-9
140-88-5
141-78-6
141-78-6
141-78-6
141-79-7
141-79-7
141-97-9
142-82-5
143-22-6
Chemical Name
Tetrachloroethylene
Tetrachloroethylene
Dimethylacetamide
Dimethylacetamide
Di-tert-butylphenol
Di-tert-butylphenol
2-Napththol
Phenol, 4-(1, 1,3,3-
tetramethylbutyl)-
Ethyl acrylate
Ethyl acetate
Ethyl acetate
Ethyl acetate
Mesityl oxide
Mesityl oxide
Ethyl acetoacetate
n-Heptane
Triethylene glycol
monobutyl ether
Source
ATSDR
OECD/SIDS/EU v
ITC/35
OECD/SIDS/IT
ITC/18
OECD/SIDS/CH
OECD/SIDS/DE
OECD/SIDS/CH
OPPT/NCP/ACR
OECD/SIDS/US
OPPT/N
ITC/27
OECD/SIDS/US
ITC/4
OECD/SIDS/EU
ITC/31
OECD/SIDS/NL
Year
Added
1994
1994
1994
1992
1990
1990
1992
1992
1992
1995
1991
1992
1992
1990
1994
1993
1990
Status
TADU
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
Removed- 199 5
CTPU-VTA
CTPU-ECA
CTPU-VTA
CTPU-VTA ^
Removed- 1993
CTPU-VTA
TADU
Removed- 1994
Health Effects
ACUTE; DEVEL;
IMMUN;
SIDS
Skin Absorption Rate
SIDS -
SIDS
SIDS
SIDS
PK;
SIDS
NEURO
SIDS
SIDS
SIDS
SIDS
Skin Absorption Rate
SIDS
Eco Effects
SIDS
SIDS
ACUTE; CHR
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS ,
SIDS
SIDS
Chemical
Fate
SIDS
SIDS
DEGR; TSPT
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
"Page 27
CAS
Number
143-33-9
143-33-9
147-14-8
149-57-5
150-76-5
151-21-3
151-50-8
1 56-43-4
156-62-7
287-92-3
294-62-2
306-83-2
320-72-9
354-33-.6
Chemical Name
Sodium cyanide
Sodium 'cyanide
C.I. Pigment Blue 15
Ethyl hexanoic acid, 2-
p-Methoxyphenol
Sodium lauryl sulfate
Potassium cyanide
Benzenamine, 4-ethoxy-
Cyanamide, calcium salt
(1:1)
Cyclopentane
Cyclododecane
2,2-Dichloro-1,1,1,2-
tetrafluoroethane
3,5-Dichlorosalicylic acid
Pentafluoroethane
s
Source
ITC/27
ATSDR
OECD/SIDS/JP
OECD/SIDS/US
ITC/32
OECD/SIDS/DE
ATSDR
OECD/SIDS/JP
OECD/SIDS/NO
ITC/31
OECD/SIDS/FR
OPPT/NCP/CFCS
OPPT/DF-OC
OPPT/NCP/CFCS
Year
Added
1992
1994
1990
1992
1993
1992
1996
1990
1993
1993
1990
1992
1990
1992
Status
Removed-1995
TADU.
Removed-1996
CTPU-VTA
TADU
CTPU-VTA
TADU
CTPU-VTA
Removed-1995
TADU
Removed- 1994
CTPU-VTA
FRM
CTPU-VTA
Health Effects
ACUTE; SCHR;
DEVEL; NEURO
SIDS
SIDS
Skin Absorption Rate
SIDS
ACUTE; SCHR;
DEVEL; NEURO
SIDS
SIDS
Skin Absorption Rate
SIDS
MUTA; ACUTE;
PCHR; DEVEL;
REPRO; SCHR;
NEURO; CHR;
CARC
MUTA; ACUTE;
DEVEL; SCHR
Eco Effects
ACUTE; CHR
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
TSPT
SIDS
SIDS
SIDS
SIDS
SIDS ,
SIDS
Product
Analysis
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 28
CAS
Number
463-58-1
482-89-3
488-47-1
504-60-9
512-56-1
527-60-6
528-29-0
532-27-4
536-90-3
540-59-0
540-88-5
540-97-6
Chemical Name
Carbonyl sulfide
3H-lndol-3-one, 2-(1,3-
dihydro-3-oxo-2H-indol-2-
ylidene)-1 ,2-dihydro-
Tetrabromocatechol
Pentadiene, 1,3-
Phosphoric acid, trimethyl
ester
Phenol, 2,4,6-trimethyl-
o-Dintrobenzene
a-Chloroacetophenone
Bepzenamine, 3-methoxy-
1 ,2-Dichloroethylene
t-Butyl acetate
Dodecamethylcyclohexa-
siloxane
Source
OAR/HAP
OECD/SIDS/JP.
OPPT/DF-OC
OECD/SIDS/US
OECD/SIDS/JP
OECD/SIDS/NL
ITC/32
ITC/31
OECD/SIDS/JP
ITC/32
ITC/31
OPPT/SILOX
Year
Added
1995
1992
1990
1990
1992
1992
1993
1993
1990
1993
1993
1996
Status
TADU
Removed- 1996
FRM
Removed- 1996
CTPU-VTA
Removed- 1995
TADU
TADU
CTPU-VTA
TADU
TADU
CTPU-VTA
Health Effects
MUTA; ACUTE;
SCHR; NEURO;
DEVEL; REPRO;
CARC; IMMUN;
SIDS.
;
SIDS
SIDS
SIDS
Skin Absorption Rate
Skin Absorption Rate
SIDS
Skin Absorption Rate
Skin Absorption Rate
PK; PCHR; IMMUN;
REPRO; DEVEL;
NEURO; SCHR;
CARC
Eco Effects
SIDS
/
SIDS
SIDS
SIDS
-
SIDS
Chemical
Fate
SIDS
Product
Analysis
SIDS
SIDS
SIDS
SIDS
MONIT;
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 29
CAS
Number
541-02-6
542-92-7
556-52-5
556-67-2
556-67-2
557-05-1
576-24-9
576-26-1
576-26-1
583-78-8
584-03-2
590-86-3
592-01-8
Chemical Name
Decamethylcyclopenta-
siloxane
Cyclopentadiene
Glycidol
Octamethylcyclotetra-
siloxane
Octamethylcyclotetra-
sitoxane
Stearic acid, zinc salt
2,3-Dichlorophenol
Dimethylphenol, 2,6-
Dimethylphenol, 2,6-
2,5-Dichlorophenol
Butanediol, 1,2-
Butanal, 3-methyl-
Calcium cyanide
Source
OPPT/SILOX
ITC/35
ITC/3
OECD/SIDS/US
OPPT/SILOX
OECD/SIDS/EU
OPPT/DF-OC
OECD/SIDS/US
ITC/27
OPPT/DF-OC
OECD/SIDS/JP
OECD/SIDS/DE
ATSDR
Year
Added
1996
1994
1992
1990
1996
1995
1990
1995
1992
1990
1990
1990
1996
Status
CTPU-VTA
TADU
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
FRM
CTPU-VTA
CTPU-VTA
FRM
Removed- 1996
CTPU-VTA
TADU
Health Effects
PK; PCHR; IMMUN;
REPRO; DEVEL;
NEURO; SCHR;
CARC;
Skin Absorption Rate
MUTA; NEURO;
REPRO
SIDS
PK; PCHR; IMMUN;
REPRO; DEVEL;
NEURO; SCHR;
CARC;
SIDS
SIDS
SIDS
-
SIDS
SIDS
ACUTE; SCHR;
DEVEL; NEURO
Eco Effects
SIDS
SIDS
SIDS ~
SIDS
SIDS
SIDS
Chemical
Fate
MONIT;
SIDS
MONIT
SIDS
Product
Analysis
SIDS
SIDS
Product
Analysis
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 30
CAS
Number
592-41-6
608-71-9
611-06-3
614-45-9
615-58-7
623-91-6
626-17-5
627-93-0
628-63-7
628-63-7
629-11-8
629-59-4
637-92-3
Chemical Name
1-Hexene
Pentabromophenol
Benzene, 2,4-dichloro-1-
nitro-
t-Butyl perbenzoate
2,4-Dibromophenol
2-Butenedioic acid (E)-,
diethyl ester
m-Phthalodinitrile
Dimethyl adipate
Amyl acetate, n-
Amyl acetate, n-
Hexamethylene glycol
Tetradecane
Ethyl t-butyl ether
Source
OECD/SIDS/US
OPPT/DF-OC
OECD/SIDS/JP
OPPT/NCP/PEROX
OPPT/DF-OC
OECD/SIDS/JP
ITC/32
OPPT/PS/DBE
OPPT/N
ITC/31
OECD/SIDS/DE
OECD/SIDS/IT
OAR/OFA
Year
Added
1992
1990
1992
1996
1990
1992
1993
1994
1991
1993
1992
1992
1994
Status
CTPU-VTA
FRM
CTPU-VTA
CTPU-VTA
FRM
CTPU-VTA
TADU
TADU
CTPU-ECA
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
Health Effects
SIDS
SIDS
Other
SIDS
Skin Absorption Rate
PK; MUTA; ACUTE;
NEURO; REPRO;
DEVEL; SCHR;
CARC;
NEURO
Skin Absorption Rate
SIDS
SIDS
PK; MUTA; NEURO;
DEVEL; REPRO;
SCHR;
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
'
Chemical
Fate
SIDS
Product
Analysis
SIDS
Product
Analysis
SIDS
<
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 31
CAS
Number
682-09-7
693-23-2
760-23-6
762-75-4
768-52-5
793-24-8
811-97-2
822-06-0
836-30-6
840-65-3
868-77-9
872-05-9
Chemical Name
Trimethylolpropane diallyl
ether
Dodecanedioic acid
3,4-Dichloro- 1 -butene
Formate, t-butyl-
N-lsopropylaniline
1 ~4-Benzenediamine/N-
(1,3-dimethylbutyl
1,1,1, 2-Tetraf luoroethane
Hexamethylene
diisocyanate, 1 ,6-
Benzenamme, 4-nitro-N-
phenyl-
Dimethyl-2,6-
naphthalenedicarboxylate
2-Hydroxyethyl
methacrylate
Decene, n-
Source
;
OECD/SIDS/DE
OECD/SIDS/US
OECD/SIDS/JP
OAR/OFA
ITC/32
OECD/SIDS/DE
OPPT/NCP/CFCS
ITC/22
OECD/SIDS/BE
OECD/SIDS/JP
OECD/SIDS/JP
OECD/SIDS/FI
Year
Added
1990
1990
1994
1996
1993
1992
1992
1990
1990
1995
1995
1990
Status
Removed- 1994
Removed-1996
CTPU-VTA
TADU
TADU-
Removed-1994
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
/
CTPU-VTA
Health Effects
SIDS
SIDS
SIDS
PK; IMMUN; MUTA;
ACUTE; SCHR;
REPRO; DEVEL;
CARC
Skin Absorption Rate
SIDS
MUTA; ACUTE;
SCHR; DEVEL; CHR;
CARC
CARC; DEVEL;
MUTA; NEURO; PK;
REPRO
SIDS
sips
SIDS
SIDS
Eco Effects
SIDS
SIDS
SIDS
SIDS
-
SIDS
SIDS
sips
SIDS
Chemical
Fate
SIDS
SIDS
SIDS
SIDS
PCHM
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 32
CAS
Number
872-50-4
923-26-2
930-37-0
933-75-5
937-41-7
994-05-8
994-05-8
1000-82-4
1 1 1 9-40-0
1120-21-4
1120-36-1
1163-19-5
Chemical Name
Methylpyrrolidone, N-
2-Hydroxypropyl-
methacrylate
Methyl glycidyl ether
2,3,6-Trichlorophenol
Phenyl acrylate
t-Amyl methyl ether
t-Amyl methyl ether
Methylol urea
Dimethyl glutarate
n-Undecane
1 -Tetradecene
Decabromodiphenyl ether
Source
CPSC
OECD/SIDS/JP .
ITC/3
OPPT/DF-OC
OPPT/NCP/ACR
OAR/OFA
OECD/SIDS/US
ITC/12
OPPT/PS/DBE
OECD/SIDS/JP
OECD/SIDS/US
ITC/25
Year
Added
1990
1994
1992
1990
1992
1994
1995
1990
1994
1994
1992
1990
Status
CTPU-ECA
CTPU-VTA
TADU
FRM
Removed-1995
CTPU-ECA
' CTPU-VTA
TNDU
TADU
CTPU-VTA
CTPU-VTA
TADU
Health Effects
CARC; NEURO; PK;
SCHR; MUTA;
DEVEL; REPRO
SIDS
-
PK; MUTA; NEURO;
DEVEL; REPRO;
SCHR;
SIDS
PK; MUTA; ACUTE;
NEURO; REPRO;
DEVEL; SCHR;
CARC;
SIDS
SIDS
CARC; DEVEL;
MUTA; NEURO;
REPRO
Eco Effects
'
SIDS
'
SIDS
SIDS
SIDS
ACUTE; CHR;
OTHR
Chemical
Fate
SIDS
Product
Analysis
PCHM;
BIOC;
SIDS
SIDS
SIDS
BIOC; DEGR;
MONIT;
PCHM; TSPT
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 33
CAS
Number
1163-19-5
1163-19-5
1163-19-5
1241-94-7
1300-73-8
1308-06-1
1 309-64-4
1313-99-1
1314-13-2
1330-78-5
1 338-23-4
1338-41-6
1 570-64-5
1 634-04-4
Chemical Name
Decabromodiphenyl ether
Decabromodiphenyl ether
Decabromodiphenyt ether
Ethylhexyl diphenyl
phosphate, 2-
Xylidine
Cobalt oxide
Antimony trioxide
Nickel (II) oxide
Zinc oxide
Tricresyl phosphate
Methyl ethyl ketone
peroxide
Sorbitan, monoocta-
decanoate
4-CWoro-2-methyl phenol
Methyl tert-butyl ether
Source
OPPT/DF-OC
OPPT/DF-OC
OECD/SIDS/EU + US
ITC/2
ITC/32
OECD/SIDS/BE
,ITC/4
OECD/SIDS/CA
OECD/SIDS/EU
ITC/2
OPPT/NCP/PEROX
OECD/SIDS/JP
OECD/SIDS/EU
OECD/SIDS/UK + US
Year
Added
1990
1990
1990
1992
1993
1994
1990
1994
1995
1992
1996
1994
1994
1995
Status
Removed- 1995
FRM
CTPU-VTA
TADU
TADU
CTPU-VTA
Removed-1994
CTPU-VTA
CTPU-VTA .
TADU
CTPU-VTA
CTPU-VTA
CTPU-VTA
CTPU-VTA
Health Effects
SIDS
DEVEL; NEURO;
REPRO
Skin Absorption Rate
SIDS
EPID
SIDS
SIDS
DEVEL; NEURO;
REPRO
Other
SIDS
SIDS
SIDS
Eco Effects
SIDS
CHR
SIDS
SIDS
SIDS
CHR
SIDS
SIDS
SIDS
Chemical
Fate
Product
Analysis
Product
Analysis
SIDS
DEGR
SIDS
SIDS
SIDS
DEGR
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page34
CAS
Number
1634-04-4
1675-54-3
1680-21-3
»
1717-00-6
1758-73-2
1854-26-8
1879-09-0
1912-24-9
1940-42-7
2156-96-9
2210-79-9
Chemical Name
Methyl tert-butyl ether
Bisphenol A diglycidyl
ether
Triethylene glycol
diacrylate
1 , 1 -Dichloro- 1 -f luoro-
ethane
Methanesulfinic acid,
aminoimino-
2-lmidazolidinone, 4,5-
dihydroxy-1,3-bis
6-tert-Butyl-2,4-xylenol
Atrazine
-4-Bromo-2,5-dichloro-
phenol
Decyl acrylate
Cresyl glycidyl ether, o-
Source
ITC/20
ITC/3
OPPT/NCP/ACR
OPPT/NCP/CFCS
OECD/SIDS/AT
OECD/SIDS/DE
OECD/SIDS/JP
OECD/SIDS/CH
OPPT/DF-OC
OPPT/NCP/ACR
ITC/3
Year
Added
1990
1992
1992
1992
1990 .
1992
1992
1992
1990
1992
1992
Status
Removed- 1993
CTPU-ECA
Removed-1995
CTPU-VTA
CTPU-VTA
CTPU-VTA
r
CTPU-VTA
Removed- 1994
FRM
Removed-1995
TADU
Health Effects
CARC; MUTA;
NEURO; DEVEL;
REPRO
CARC; DEVEL;
MUTA; NEURO;
REPRQ; SCHR
OTHR; PK; PCHR;
SCHR; CARC
MUTA; ACUTE;
PCHR; NEURO;
DEVEL; REPRO;
SCHR; CHR; CARC
SIDS
SIDS
SIDS
SIDS
DEVEL; MUTA;
NEURO; SCHR
Eco Effects
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
PCHM;
BIOC;
SIDS
SIDS
SIDS
SIDS
Product
'Analysis
PCHM;
BIOC;
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
?age 35
CAS
Number
2223-82-7 .
2224-15-9
2238-07-5
2402-79-1
2425-01-6
2425-79-8
2426-08-6
2431-50-7
2439-35-2
2461-15-6
2461-18-9
2524-03-0
Chemical Name
Neopentyl glycol
diacrylate
Ethylene glycol diglycidyl
ether >
Diglycidyl ether
Tetrachloropyridine,
2,3,5,6-
Hydroquinone diglycidyl
ether
Butanediol diglycidyl
ether, 1 ,4-
Butyl glycidyl ether, n-
Butene, 2,3,4-trichloro-,
1-
2-(Dimethylamino)ethyl
acrylate
Ethylhexyl glycidyl ether,
2-
Lauryl glycidyl ether
Dimethyl chlorothio-
phosphate
Source
OPPT/NCP/ACR
ITC/3
ITC/3
OECD/SIDS/US
ITC/3
ITC/3
ITC/3
OECD/SIDS/DE .
OECD/SIDS/JP
ITC/3
ITC/3
OECD/SIDS/US
Year
Added
1992
1992
1992
1990
1992
1992
1992
1990
1995
1992
1992
1992
Status
Removed-1995
TADU
TADU
'Removed-1996
TADU
TADU '
TADU
Removed-1996
CTPU-VTA
TADU
TADU
CTPU-VTA
Health Effects
-
SIDS
MUTA; NEURO;
SCHR
CARC; DEVEL;
MUTA; NEURO;
REPRO; SCHR
SIDS
SIDS
CARC; MUTA; SCHR
SIDS
Eco Effects
SIDS
-
SIDS
SIDS
SIDS
Chemical
Fate
PCHM; BIOC
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 36
CAS
Number
2524-04-1
2528-36-1
2530-83-8
2536-05-2
2577-72-2
2581-34-2
2720-73-2
2837-89-0
2897-60-1
3039-83-6
3048-65-5
Chemical Name
Diethyl chlorothio-
phosphate
Di(n-butyl) phenyl
phosphate
Glycidoxypropyltrimeth-
oxysilane, gamma-
Benzene, 1,1'-methylene-
bis[2-isocyanato-
3,5-Dibromosalicylanilide
Phenol, 3-methyl-4-nitro-
Potassium pentylxanthate
2-Chloro-1,1,1,2-tetra-
fluoroethane
3-(MethyldiethoxysilyD-
propyl glycidyl ether
Ethenesulfonic acid,
sodium salt
1H-lndene, 3a,4,7,7a-
tetrahydro-
Source
OECD/SIDS/US
ITC/2
ITC/3
OECD/SIDS/US
OPPT/DF-OC
OECD/SIDS/JP
OECD/SIDS/CA
OPPT/NCP/CFCS
ITC/3
OECD/SIDS/BE
OECD/SIDS/JP
Year
Added
1992
1992
1992
1994
1990
1992
1990
1992
1992
1992
1995
Status
CTPU-VTA
TADU
TADU
CTPU-VTA
FRM
CTPU-VTA
Removed- 1994
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
Health Effects
SIDS
DEVEL; NEURO;
REPRO -
CARC; DEVEL;
MUTA; NEURO;
REPRO; SCHR
SIDS
SIDS
SIDS
MUTA; ACUTE;
PCHR; NEURO;
DEVEL; SCHR; CHR;
CARC
SIDS
SIDS
Eco Effects
SIDS
CHR
SIDS
SIDS
SIDS
"
SIDS
SIDS
Chemical
Fate
SIDS
DEGR
SIDS
Product
Analysis
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
'VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 37
CAS
Number
3072-84-2
3101-60-8
3188-83-8
3194-55-6
3209-22-1
3377-92-2
3443-12-4
3452-97-9
3568-29-4
3772-94-9
3926-62-3
Chemical Name
Tetrabromobisphenol A
diglycidyl ether,
2, 2', 6,6'-
Butylphenyl glycidyl
ether, p-tert-
2-Methylol-4,4'-
isopropylidene-diphenol
diglycidyl ether
Cyclododecane,
1,2,5,6,9,10-hexabromo-
Benzene, 1,2-dichloro-3-
nitro-
Vinyl pivalate
o,o-t-Butyl O-(2:ethyl-
hexyl) monoperoxy
carbonate
3,5,5-Trimethylhexan-1-ol
Glycerol 1 ,3-diglycidyl
ether
Pentachlorophenyl laurate
Acetic acid, chloro-,
sodium salt
Source
ITC/3
ITC/3
ITC/3
ITC/25
QECD/SIDS/JP
OPPT/NCP/VE
OPPT/NCP/PEROX
OECD/SIDS/JP
ITC/3
OPPT/DF-OC
OECD/SIDS/SE
Year
Added
1992
1992
1992
1990
1990
1993
1996
1995
1992
1990
1992
Status
TADU
TADU
TADU
TADU
X
CTPU-VTA
CTPU-ECA
CTPU-VTA
CTPU-VTA
TADU
FRM
CTPU-VTA
Health Effects
CARC; CHR; DEVEL;
MUTA; NEURO; '
REPRO
SIDS
SCHR; NEURO;
DEVEL; REPRO;
CARC
Other
SIDS
SIDS
Eco Effects
ACUTE; CHR;
"OTHR
SIDS
SIDS
SIDS
Chemical
Fate
\
BIOC; DEGR;
PCHM; TSPT
SIDS
SIDS
Product
Analysis
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU -= Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 38
CAS
Number
4016-11-9
4016-14-2
4074-88-8
4162-45-2
4162-45-2
4170-30-3
4259-15-8
4457-71-0
4461-52-3
4813-57-4
4979-32-2
4986-89-4
5026-74-4
5160-02-1
Chemical Name
Ethyl glycidyl ether
Isopropyl glycidyl ether
Diethylene glyool
diacrylate
Tetrabromobisphenol A
bis(ethoxylate)
Tetrabromobisphenol A
bis(ethoxylate)
Crotonaldehyde
Phosphorodithioic acid,
O,O-bis(2-ethyln-
3-Methyl-1 ,5-pentanediol
Methoxymethanol
Stearyl acrylate
N,N-Dicyclohexyl-2-
benzothiazolesulfenam
Pentaerythritol tetra-
acrylate
4-(Diglycidylamino)phenyl
glycidyl ether
Pigment Red (53:1)
barium salt
Source
ITC/3
ITC/3
OPPT/NCP/ACR
OPPT/DF-OC
OPPT/DF-OC
ITC/22
OECD/SIDS/US
OECD/SIDS/JP
OECD/SIDS/JP
OPPT/NCP/ACR
OECD/SIDS/JP
OPPT/NCP/ACR
/
ITC/3 .
OECD/SIDS/DE
Year
Added
1992
1992
1992
1990
1990
1990
1992
1995
1992
1992
1992
1992
1992
1994
Status
TADU
TADU
Removed-1995
FRM
Removed- 1993
Removed-1993
CTPU-VTA
CTPU-VTA
Removed-1994
Removed-1995
CTPU-VTA
Removed-1995
TADU
CTPU-VTA
Health Effects
^
SIDS
sibs
SIDS
PK
SIDS
MUTA
SIDS
Eco Effects
CHR
SIDS
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
PCHM;
BIOC;
Product
Analysis
Product
Analysis
SIDS
SIDS
SIDS
'PCHM;
BIOC;
SIDS
PCHM;
BIOC;
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 39
CAS
Number
5255-75-4
5281--04-9
5392-40-5
5493-45-8
5873-54-1
6178-32-1
6285-32-1
6386-38-5
6419-19-8
6423-43-4
6742-54-7
6846-50-0 '
Chemical Name
Nitrophenyl glycidyl ether,
P-
D&C Red No. 7
Citral
Diglycidyl ester of hexa-
hydro-phthalic acid
Benzene, 1 -isocyanato-2-
[(4-isocyanatophenyl)-
methyl]-
p-Nonylphenyl glycidyl
ether
m,p-t-Butyl isopropyl
benzene hydroperoxide
(mixture)
Benzenepropanoic acid,
3,5-bis(1,1-di-methyl-
ethyl)-
Phosphoric acid, [nitrilo-
tris(methylene)]tris-
Propylene glycol dinitrate
Benzene, undecyl-
2,2,4-Trimethyl-1,3-
pentanediol ester
Source
ITC/3
OECD/SIDS/JP
OECD/SIDS/JP
ITC/3
OECD/SIDS/US
ITC/3
OPPT/NCP/PEROX
OECD/SIDS/CH
OECD/SIDS/UK
ITC/32
OECD/SIDS/US
OECD/SIDS/JP
Year
Added
1992
1992
1992
1992
1994
1992
1996
1990
1990
1993
1992
1992
Status
TADU
Removed- 1996
CTPU-VTA
TADU
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
Removed- 1996
TADU
CTPU-VTA
CTPU-VTA
Health Effects
SIDS
SIDS '
CARC; MUTA; SCHR
SIDS
Other
SIDS
SIDS
Skin Absorption Rate
SIDS
SIDS
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS l-
SIDS
SIDS
Chemical
Fate
SIDS
SIDS
SIDS
'
SIDS
SIDS
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU. = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 40
CAS
Number
7195-45-1
7328-97-4
7422-52-8
7440-66-6
7631-90-5
7646-85-7
7647-01"-0
7664-39-3
7664-39-3
7665-72-7
7681-52-9
7681-57-4
7722-84-1
7722-84-1
7723-14-0
Chemical Name
Diglycidyl ester of
phthalic acid
1 , 1 ,2,2-Tetra(p-hydroxy-
phenyllethane tetra-
glycidyl ether
3-[Bis(trimethylsildxy)-
methyD-propyl glycidyl
ether
Zinc
Sodium bisulfite
Zinc chloride
Hydrochloric acid
Hydrofluoric acid
Hydrofluoric acid
Butyl glycidyl ether, tert-
Sodium hypochlorite
Sodium metabisulfite
Hydrogen peroxide
Hydrogen peroxide
Phosphorus, white
Source
ITC/3
ITC/3
ITC/3
OECD/SIDS/EU
ITC/3 1
OECD/SIDS/EU
OAR/HAP
OECD/SIDS/EU
OAR/HAP
ITC/3
OECD/SIDS/EU
ITC/3 1
OPPT/NCP/PEROX
OECD/SIDS/EU
DOI
Year
Added
1992
1992
1992
1995
1993
1995
1995
1994
1995
1992
1995
1993
1996
1994
1996
Status
TADU
TADU
TADU
CTPU-VTA
TADU
CTPU-VTA
TADU
CTPU-VTA
TADU
TADU
CTPU-VTA
TADU
CTPU-VTA
CTPU-VTA
TADU
Health Effects
SIDS
Skin Absorption Rate
SIDS
ACUTE;
SIDS
ACUTE; SCHR;
DEVEL; REPRO;
NEURO; IMMUN;
SCHR
SIDS
Skin Absorption Rate
Other
SIDS
Eco Effects
SIDS
SIDS
SIDS
SIDS
SIDS
ACUTE
Chemical
Fate
SIDS
SIDS
SIDS
-
SIDS
SIDS
TSPT
TNDU = Testing Needs Development,Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
age 41
CAS
Number
7723-14-0
7733-02-0
7779-90-0
7782-50-5
7784-18-1
9011-05-6
9016-87-9
11070-44-3
13048-33-4
13236-02-7
13533-05-6
13561-08-5
13674-84-5
14228-73-0
Chemical Name
Phosphorus, white
Zinc sulfate
Zinc ortho-phosphate
Chlorine
Aluminum fluoride
Urea-formaldehyde resin
Isocyanic acid, poly-
methylenepolyphenylene
ester (Polymeric MDI)
1 ,3-lsobenzofurandione,
tetrahydromethyl-
Hexamethylene glycol
diacrylate
Glycerol triglycidyl ether
Diethylene glycol
monoacrylate
Diglycidylphenyl glycidyl
ether, 2,6-
2-Propanol, 1-chloro-,
phosphate (3:1)
Bis(glycidyloxymethyl)
cyclohexane, 1 ,4-
Source
ITC/34
OECD/SIDS/EU
OECD/SIDS/EU
OAR/HAP
OECD/SIDS/NO
ITC/12
OECD/SIDS/US
OECD/SIDS/JP
OPPT/NCP/ACR
ITC/3
OPPT/NCP/ACR
ITC/3
OECD/SIDS/US
ITC/3
Year
Added
1994
1995
1995
1995
1993
1990
1994
1995
1992
1992
1992
1992
1992
1992
Status
Removed- 1996
CTPU-VTA
CTPU-VTA
TADU
Removed-1995
TNDU
CTPU-VTA
CTPU-VTA
Removed-1995
TADU
Removed-1995
TADU
CTPU-VTA
TADU
Health Effects
SIDS
SIDS
ACUTE?
SIDS
SIDS
SIDS
SIDS
Eco Effects
ACUTE
SIDS
SIDS
SIDS
SIDS ...
SIDS
1
SIDS
Chemical
Fate
TSPT
SIDS
SIDS
SIDS
SIDS ~
SIDS
PCHM;
BIOC;
PCHM;
BIOC;
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 42
CAS
Number
15625-89-5
15965-99-8
16245-97-9
16470-24-9
16529-56-9
17557-23-2
17831-71-9
17963-04-1
20217-01-0,
21850-44-2
22421-59-6
24493-53-6
24800-44-0
Chemical Name
Trimethylolpropane
triacrylate
Hexadecyl glycidyl ether
Octadecyl glycidyl ether,
n-
Fluorescent whitening
agent (stilbene-based)
3-Butenonitrile, 2-methyl-
Neopentyl glycol
diglycidyl ether
Tetraethylene glycol
diacrylate
3-(Dimethylethoxysilyl)-
propyl glycidyl ether
Dibromophenyl glycidyl
ether, 2,4-
Tetrabromobisphenol A
bis(2,3-dibromopropyl
ether)
Dibromo-4-methylphenyl
glycidyl ether, 2,6-
1,3-Propanediol diacrylate
Tripropylene glycol
Source
OPPT/NCP/ACR
ITC/3
ITC/3
OPPT/NCP/FWA
.OECD/SIDS/FR
ITC/3
OPPT/NCP/ACR
ITC/3
ITC/3
OPPT/DF-OC
ITC/3
OPPT/NCP/ACR
OECD/SIDS/JP
Year
Added
1992
1992
1992
1993
1990
1992
1992
1992
1992
1990
1992
1992
1992
I Status
Removed-1995
TADU
TADU
TADU
Removed- 19 94
TADU
Removed-1995
TADU
TADU
FRM
TADU
Removed-1995
Removed- 1996
Health Effects
-
SCHR; DEVEL;
REPRO;
SIDS
CARC; SCHR
SIDS '
Eco Effects
SIDS
<
SIDS
Chemical
Fate
PCHM;
BIOC;
SIDS
PCHM;
BIOC;
Product
Analysis
PCHM;
BIOC;
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 43
CAS
Number
25013-15-4
25154-52-3
25155-23-1
25155-30-0
25167-70-8
25265-77-4
25327-89-3
25327-89-3
25637-99-4
26322-14-5
26444-49-5
26447-14-3
26447-40-5
Chemical Name
Vinyl toluene
Nonylphenol ethoxylates
Phosphate, trixylyl
Sodium dodecylbenzene
sulfonate
Pentene, 2,4,4-trimethyl-
Propanoic acid,"2-methyl-
, monoester with 2,2,4-
trimethyl-1 ,3-pentanediol
Tetrabromobisphenol A,
allyl ether
Tetrabromobisphenol A
allyl ether
Cyclododecane, hexa-
bromo-
Dicetyl peroxydicarbonate ~
Phosphoric acid,
methylphenyldiphenyle
Cresyl glycidyl. ether
(mixed isomers)
Benzene, 1,1 '-methylene-
bis[isocyanato-
Source
ITC/32
OECD/SIDS/EU + US
ITC/2
OECD/SIDS/NO
OECD/SIDS/EU
OECD/SIDS/US
OPPT/DF-OC
OPPT/DF-OC
OECD/SIDS/EU
OPPT/NCP/PEROX
OECD/SIDS/JP
ITC/3
OECD/SIDS/US
Year
Added
1993
1995
1992
1993
1995
1990
1990
1990
1995
1996
1992
1992
1994
Status
TADU
CTPU-VTA
TADU
Removed- 1995
CTPU-VTA
Removed- 1996
Removed- 1994
FRM
CTPU-VTA
CTPU-VTA
CTPU-VTA
TADU
CTPU-VTA
Health Effects
Skin Absorption Rate
SIDS
DEVEL; NEURO;
REPRO
SIDS
SIDS
SIDS
-
SIDS
Other
SIDS
SIDS
Eco Effects
SIDS
CHR
SIDS
SIDS
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
SIDS
DEGR
SIDS
SIDS
SIDS
Product
Analysis
Product
Analysis
SIDS
1
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 44
CAS
Number
26761-40-0
26761-45-5
26967-76-0
27193-86-8
28108-99-8
28553-12-0
28629-66-5
29171-20-8
29590-42-9
29761-21-5
32055-14-4
32466-46-9
32534-81-9
32534-81-9
Chemical Name
Diisodecyl phthalate
Glycidyl ester of
neodecanoic acid
Phosphate, tris(isopropyl-
phenyl)
Dodecylphenol
Isopropylphenyl diphenyl
phosphate
Diisononyl phthalate
Phosphorodithioic acid,
O,O-diisooctyl
6-Octen-1-yn-3-ol, 3,7-
dimethyl-
Isooctyl acrylate
Isodecyl diphenyl
phosphate
MDI Polymer
Fluorescent whitening
agent (stilbene-based)
Pentabromodiphenyl ether
Pentabromodiphenyl ether
Source
OECD/SIDS/EU
ITC/3
ITC/2
OPPT/RD
ITC/2
OECD/SIDS/EU
OECD/SIDS/US
OECD/SIDS/CH
OECD/SIDS/US
ITC/2
OECD/SIDS/US
OPPT/NCP/FWA
ITC/25
OECD/SIDS/EU
Year
Added
1995
1992
1992
1991
1992
1995
1992
1990
1990
1992
1994
1993
1990
1995
Status
CTPU-VTA
TADU
TADU
TADU
TADU
CTPU-VTA
CTPU-VTA
Removed-1996
Removed-1996
TADU
CTPU-VTA
TADU
TADU
CTPU-VTA
Health Effects
SIDS
DEVEL; MUTA;
NEURO; SCHR
DEVEL; NEURO;
REPRO
DEVEL
DEVEL; NEURO;
REPRO
SIDS
SIDS
SIDS
SIDS
DEVEL; NEURO;
REPRO
SIDS
SCHR; DEVEL;
REPRO;
CARC; CHR; DEVEL;
MUTA; NEURO;
REPRO
1
SIDS
Eco Effects
SIDS
CHR
CHR
SIDS
SIDS
SIDS
SIDS
CHR
SIDS
ACUTE; CHR;
OTHR
SIDS
Chemical
Fate
SIDS
DEGR
DEGR
SIDS
SIDS
SIDS '
SIDS
DEGR
SIDS
BIOC; DEGR;
MONIT;
PCHM; TSPT
SIDS
TNDU = Testing Needs Development Underway
TADU =. Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement.
-------
INDEX I. MASTER TESTING LIST
Tage 45
CAS
Number
32534-81-9
32534-81-9
32536-52-0
32536-52-0
32536-52-0
32536-52-0
32568-89-1
34590-94-8
35243-89-1
37853-59-1
37853-59-1
Chemical Name
Pentabromodiphenyl ether
Pentabromodiphenyl ether
Octabromodiphenyl ether
Octabromodiphenyl ether
Octabromodiphenyl ether
Octabromodiphenyl ether
3-(2-Glycidyloxypropyl)-1-
glycidol-5,5-dimethyl-
hydantoin
Dipropylene glycol methyl
ether
Dibromopropyl glycidyl
ether, 1,2-
Ethane, 1,2-bis(2,4,6-
tribromophenoxy)-
Ethane, 1,2-bis(2,4,6-
tribromophenoxy)-
Source
OPPT/DF-OC
OPPT/DF-OC
ITC/25
OECD/SIDS/EU
OPPT/DF-OC
, OPPT/DF-OC
ITC/3 '
ITC/35
ITC/3
OPPT/DF-OC
OPPT/DF-OC
Year
Added
1990 '
1990
1990
1994
1990
1990
1992
1994
1992
1990
1990
Status
Removed- 1995
FRM
TADU
CTPU-VTA
FRM "
Removed-1995
TADU
TADU
TADU
Removed- 1996
FRM
Health Effects
CARC; CHR; DEVEL;
MUTA; NEURO;
REPRO
SIDS
. -
Skin Absorption Rate
Eco Effects
-
ACUTE; CHR;
OTHR
SIDS
-
-
Chemical
Fate
Product
Analysis
Product
Analysis
BIOC; DEGR;
MONIT;
PCHM; TSPT
SIDS
Product
Analysis
Product
Analysis
-
Product
Analysis
Product
Analysis
TNDU = Testing Needs.Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 46
CAS
Number
37853-59-1
37853-61-5
37971-36-1
38304-52-8
38954-75-5
54208-63-8
55205-38-4
56803-37-3
60501-41-9
61578-04-9
61790-33-8
63148-62-9
Chemical Name
Ethane, 1 ,2-bis(2,4,6-
tribromophenoxy)-
Tetrabromobisphenol B
Butanetricarboxylic acid,
2-phosphono-1 ,2,4-
1 ,3-Bis(5, 5-dimethyl- 1 -
glycidyl-hydantoin-3-yl)-2-
glycidyl ether
Tetradecyl glycidyl ether
Bisphenol F diglycidyl
ether
Tetrabromobisphenol A
diacrylate
Phosphate, tert-butyl-
phenyl diphenyl
Oleyl glycidyl ether
Cumylphenyl glycidyl
ether, p-
Amines, tallow alkyl
Polydimethylsiloxane
(350 centistoke)
Source
ITC/25
OPPT/DF-OC
OECD/SIDS/DE
ITC/3
ITC/3
ITC/3
OPPT/DF-OC
ITC/2
ITC/3
ITC/3
OECD/SIDS/EU
OPPT/SILOX
Year
Added
1990
1990
1990"
1992
1992
1992
1990
1992
1992
1992
1995
1996
Status
TADU
FRM
Removed- 1996
TADU
TADU
TADU
FRM
TADU
TADU
TADU
CTPU-VTA
CTPU-VTA
Health Effects
CARC; CHR; DEVEL;
MUTA; NEURO;
REPRO
SIDS
DEVEL; NEURO;
REPRO
-
SIDS
PK; PCHR; IMMUN;
REPRO; DEVEL;
NEURO; SCHR;
CARC;
Eco Effects
ACUTE; CHR;
OTHR
SIDS
'>
CHR
SIDS
Chemical
Fate
BIOC; DEGR;
MONIT;
PCHM; TSPT
Product
Analysis
SIDS
Product
Analysis
DEGR
SIDS
MONIT;
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX!. MASTER TESTING LIST
Page 47
CAS
Number
63148-62-9
65652-41-7
65996-92-1
67774-74-7
67786-03-2
67952-50-5
68081-84-5
68134-06-5
68134-07-6
68442-69-3
68515-48-0.
Chemical Name
Polydimethylsiloxane (10
centistoke)
Phosphate, bis(tert-butyl-
phenyl) phenyl
Distillates (coal tar)
Benzene, C10-C13 alkyl
derivatives
[Bis(4-glycidyloxy-
phenyl)]-(2-glycidyl-
oxyphenyDmethane
( 1 -Methylethylidene)-
bis(4, 1 -phenyleneoxy)(1 -
methyl-2, 1 -ethanediyl)
diacrylate
Alkyl (C10-C16) glycidyl
ether
Dimethylbutyl glycidyl
ether,. 1,3-
Methylheptyl glycidyl
ether, 6-
Benzene, C10-C14 alkyl
derivatives
Di(C8-C10) branched
alkyl phthalate
Source
OPPT/SILOX
ITC/2
OECD/SIDS/EU
OECD/SIDS/EU
ITC/3
OPPT/NCP/ACR .
ITC/3
ITC/3
ITC/3
OECD/SIDS/US
OECD/SIDS/EU
Year
Added
1996
1992
1994
1994
1992
1992
1992
1992
1992
1994
1995
Status
CTPU-VTA
TADU
Removed-1995
CTPU-VTA
TADU
Removed-1995
TADU
TADU
TADU
CTPU-VTA
CTPU-VTA
Health Effects
PK; PCHR; IMMUN;
REPRO; DEVEL;
NEURO; SCHR;
CARC;
DEVEL; NEURO;
REPRO
SIDS
SIDS
SCHR
SIDS
SIDS
Eco Effects
CHR
SIDS
SIDS
SIDS
SIDS
Chemical
Fate
MONIT;
DEGR
SIDS
SIDS
PCHM;
BIOC;
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 48
CAS
Number
68515-49-1
68517-02-2
68609-96-1
68609-97-2
68611-64-3 '
68648-86-2
68648-87-3
68937-41-7
68959-23-9
68987-80-4
69155-42-6
71033-08-4
Chemical Name
DKC9-C11) branched
alkyl phthalate
Tris(4-hydroxyphenyl)-
propane-triglycidyl ether
Alkyl (C8-C10) glycidyl
ether
Alkyl (C12-C14) glycidyl
ether
Urea-formaldehyde resin
Benzene, C4-C16 alkyl
derivatives
Benzene, C10-C16 alkyl
derivatives
Phenol Isopropylated
phosphate
Hexanetrio'l triglycidyl
ether, 1,2,6-
Alkyl (C6;C12) glycidyl
ether
1,1, 1,3,5,7, 7, 7-Octa-
methyl-3,5-bis(6,7-epoxy-
4-oxaheptyl)-
2,2-Bis[p-2-glycidyloxy-3-
butoxypropyloxyl-phenyl)-
propane
Source
OECD/SIDS/EU
ITC/3
ITC/3
ITC/3
ITC/12
OECD/SIDS/US
OECD/SIDS/US
ITC/2
ITC/3 .
ITC/3
ITC/3
ITC/3
Year
Added
1995
1992
1992
1992
1990
1994
1994
1992
1992
1992
1992
1992
Status
CTPU-VTA
TADU
TADU
TADU
TNDU
CTPU-VTA
CTPU-VTA
TADU
TADU
TADU
TADU
TADU
Health Effects
SIDS
REPRO; SCHR
DEVEL; MUTA;
NEURO; SCHR
SIDS
SIDS
DEVEL; NEURO;
REPRO
.-
Eco Effects
SIDS
-
SIDS
SIDS
CHR
Chemical
Fate
SIDS
SIDS
SIDS
DEGR
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 49
CAS
Number
71808-64-5
72319-24-5
74398-71-3
75150-13-9
84852-15-3
84852-15-3
84852-15-3
85535-84-8
97380-66-0
120547-52-6
129813-58-7
129813-59-8
Chemical Name
Dimethoxysilane, (3-
glycidoxy-propyl)(3-
chloropropyl)-
2,2'-[(1-Methyl-
ethylidene)bis[4, 1 -
phenyleneoxy-3, 1 -
propanedioxy
1,2,3-Propanetriyl ester
of 1 2-(oxiranylmethoxy)-
9-octadecanoic acid
2,4-Dibromo-6-methyl-
phenyl glycidyl ether
Nonylphenol, 4-branched
Nonylphenol, 4-branched
Nonylphenol, 4-branched
Alkanes, C10-C13,
chloro-
Urea-formaldehyde resin
Alkyl (C12-C13) glycidyl
ether
Benzene, C10-13 alkyl
derivatives
Benzene, C12-C14 alkyl
derivatives
Source
ITC/3
ITC/3
ITC/3
ITC/3
OECD/SIDS/EU + US
OPPT/NP
QPPT/NP
OECD/SIDS/EU
ITC/12
ITC/3 "
OECD/SIDS/US
OECD/SIDS/US
Year
Added
1992
1992
1992
1992
1995
1992
1996
1994
\
1990
1994
1994
1994
Status
TADU
TADU
TADU
TADU
CTPU-VTA
Removed- 1993
TADU
CTPU-VTA
TNDU
CTPU-ECA
CTPU-VTA
CTPU-VTA
Health Effects
-
DEVEL; MUTA;
NEURO; SCHR
SIDS
SIDS
MUTA; NEURO;
SCHR; REPRO;
DEVEL;
SIDS
SIDS
Eco Effects
SIDS
CHR; ACUTE
CHR
SIDS
-
'
SIDS
SIDS
Chemical
Fate
SIDS .
PCHM; BIOC
SIDS
_
SIDS
SIDS
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway.
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX I. MASTER TESTING LIST
Page 50
CAS
Number
129813-60-1
142844-00-6
Chemical Name
Benzene, C14-C16 alkyl
derivatives
Refractory ceramic fibers
Source
OECD/SIDS/US
OPPT/RF
Year
Added
1994
1992
Status
CTPU-VTA
CTPU-ECA
Health Effects
SIDS
Eco Effects
SIDS
\
Chemical
Fate
SIDS
Exposure
Monitoring
TNDU = Testing Needs Development Underway
TADU = Testing Action Development Underway
CTPU = Chemical Testing Program Underway
FRM = TSCA Section 4 Final Rule Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX II. CHEMICALS REMOVED FROM THE MASTER TESTING LIST
Page 1
CAS
Number
NONE
NONE
50-81-7
57-13-6
59-67-6
60-29-7
67-63-0
70-55-3
71-36-3
Chemical Name
Carpet-TVOC
Commercial hexane
L-Ascorbic acid
Urea
Pyridinecarboxylic acid, 3-
Diethyl ether
Isoprppanol
Benzenesulfonamide, 4-
methyl-
Butanol, 1-
Source
OPPT/CCP
ITC/16
OECD/SIDS/UK
OECD/SIDS/FI
OECD/SIDS/CH
OPPT/N
ITC/20
OECD/SIDS/JP
ITC/28
Year
Added
1992
199O
1992
1992
1990
1991
199O
199O
1992
Year
Removed
1996
1993
1996
1996
4996
1995
1994
1996
1993
Removal
Rationale
VTA Testing
Program Completed
FRM Testing
Program Completed
VTA .Testing
Program Completed
VTA Testing
Program Completed
VTA Testing
Program Completed
Testing requirement
withdrawn by OPPT
FRM Testing
Program Completed
VTA Testing
Program Completed
Testing designation
withdrawn by ITC
Comments
«4
Chemical remains on MTL
because of additional testing
actions (see ITC Skin Absorption
Rate listing)
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS listing)
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS listing)
FRM = TSCA Section 4 Final Rule-Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX II. CHEMICALS REMOVED FROM THE MASTER TESTING LIST
Page 2
CAS
Number
71-36-3
71-55-6
74-87-3
75-00-3
75-01-4
75-02-5
75-34-3
75-38-7
Chemical Name
Butanol, 1 -
Trichloroethane, 1,1,1-
Chloromethane
Chloroethane
Vinyl chloride
Vinyl fluoride
1,1-Dichloroethane
Vinylidene fluoride
Source
OPPT/N
ITC/2
OW/ODW
OW/ODW
ATSDR
ITC/7
OW/ODW
ITC/7
Year
Added
1991
4
1990
1990
1990
1994
1990
1990
1990
Year
Removed
1995
1993
1993
1996
1996
1993
1995
1993
Removal
Rationale
Testing requirement
withdrawn by OPPT
EGA Testing
Program Completed
Testing requirement
withdrawn by OPPT
Testing requirement
withdrawn by OPPT
Testing request
withdrawn by
ATSDR
FRM Testing
Program Completed
Testing requirement
withdrawn by OPPT
FRM Testing
Program Completed
Comments
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS listing).
Note: the results of ongoing
testing of n-butyl acetate (CAS
No. 123-86-4) via a TSCA
section 4 EGA will determine the
need for neurotoxicity testing of
1-butanol
Chemical remains on MTL
because of additional testing
actions (see ATSDR listing)
*
Chemical remains on MTL
because of additional testing
actions (see ITC Skin Absorption
Rate listing)
FRM = TSCA Section 4 Final Rule-Making
ECA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement.
-------
INDEX II. CHEMICALS REMOVED FROM THE MASTER TESTING LIST
PageS
CAS
Number
75-69-4
75-86-5
75-98-9
77-99-6
78-83-1
78-97-7
79-00-5
79-10-7
79-34-5
Chemical Name
Fluorotrichloromethane
Acetone cyanhydrin
2,2-Dimethylpropanoic acid
Propanediol, 2-ethyl-2-
(hydroxymethyl)-, 1 ,3-
Isobutyl alcohol
Propanenitrile, 2-hydroxy-
1,1, 2-Trichloroethane
Acrylic acid
Tetrachloroethane, 1,1,2,2-
Source
OW/ODW
OECD/SIDS/UK
OECD/SIDS/NL
OECD/SIDS/JP
ITC/28
OECD/SIDS/JP
OW/ODW
ITC/27
OW/ODW
Year
Added
1990
1992
1992
199O
1992
1992
1990
1992
199O
Year
Removed
1993
1996
1995
1996
1993
1996
1993
1994
1996
Removal
Rationale
Testing requirement
withdrawn by OPPT
VTA Testing
Program Completed
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
Testing designation
withdrawn by ITC
VTA Testing
Program Completed
Testing requirement
withdrawn by OPPT
EGA Testing
Program Completed
FRM Testing
Program Completed
Comments
^
Chemical remains on MTL -
because of additional testing
actions (see OECD/SIDS, ITC
Skin Absorption Rate and OPPT
Neurotoxicity listings)
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS and
Hazardous Air Pollutants listings)
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS listing)
FRM = TSCA Section 4 Final Rule-Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX II. CHEMICALS REMOVED FROM THE MASTER TESTING LIST
Page 4
CAS
Number
79-92-5
79-94-7
79-94-7
80-43-3
80-62-6
84-66-2
87-10-5
95-54-5
Chemical Name
Camphene
Tetrabromobisphenol A
Tetrabromobisphenol A
Dicumyl peroxide
Methyl methacrylate
Diethyl phthalate
Tribromosalicylanilide,
3,4', 5-
Phenylenediamine, ortho-
Source
OECD/SIDS/DE
OPPT/DF-OC
OECD/SIDS/US
OECD/SIDS/BE
ITC/32
ITC/32
OPPT/DF-OC
ITC/6
Year
Added
1990
1990
1992
1992
*
1993
1993
1990
.1990
Year
Removed
1996
1994
1994
1994
1994
1994
1992
1993
Removal
Rationale
VTA Testing
Program Completed
FRM-Testing
Program Completed
Withdrawn from
OECD/SIDS program
Withdrawn from
OECD/SIDS program
Testing designation
withdrawn by 1TC
Testing designation
withdrawn by ITC
FRM Testing -
Program Completed
FRM Testing
Program Completed
Comments
Chemical remains on MTL
because of additional testing
actions (see OPPT Dioxins/Furans
in Organic Chemicals listing)
Chemical remains on MTL
because of additional testing
actions (see OPPT New
Chemicals Program Peroxides
listing)
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS and
Hazardous Air Pollutants
Category listings)
'
Chemical remains on MTL
because of additional testing
actions (see OPPT Dioxins/Furans
in Organic Chemicals listing)
FRM = TSCA Section 4 Final Rule-Making
ECA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX II. CHEMICALS REMOVED FROM THE MASTER TESTING LIST
Page 5
CAS
Number
96-29-7
1 00-40-3
100-52-7
101-54-2
103-23-1
103-65-1
104-94-9
105-05-5
106-44-5
107-01-7
Chemical Name
Methyl ethyl ketoxime
Vinylcyclohexene, 4-
Benzaldehyde
1,4-Benzenediamine, N-
phenyl-
Di(2-ethylhexyl)adipate
Propylbenzene, n-
Aniline, 4-methoxy-
Benzene, 1,4-diethyl-
p-Cresol
Butene, 2-
Source
ITC/19
ITC/27
OECD/SIDS/NL
OECD/SIDS/DE
ITC/28
OW/ODW
OECD/SIDS/DE ,
OECD/SIDS/JP
OECD/SIDS/US
OECD/SIDS/NL
Year
Added
199O
1992
1992
1992
1 992 '
1990
1992
1992
1992
199O
Year
Removed
1994
1995
. 1996
1994
1 993
1993
1994
1996
1994
1996
Removal
Rationale
FRM Testing
Program Completed
EGA Testing
Program Completed
VTA Testing
Program Completed
Withdrawn from
OECD/SIDS program
Testing designation
withdrawn by ITC
Testing requirement
withdrawn by OPPT
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
Withdrawn from
OECD/SIDS Program
VTA Testing
Program Completed
Comments
-
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS listing)
.Chemical remains on MTL
because of additional testing
actions (see Hazardous Air
Pollutants Category listing)
FRM = TSCA Section 4 Final Rule-Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX II. CHEMICALS REMOVED FROM THE MASTER TESTING LIST
Page 6
CAS
Number
107-64-2
107-66-4
108-45-2
108-67-8
108-89-4
108-94-1
108-94-1
108-99-6
109-06-8 ,
109-16-0
110-30-5
Chemical Name
1-Octadecanaminium, N,N-
dimethyl-N-pctadecyl-,
chloride
Dibutyl phosphate
Phenylen'ediamine, meta-
Trimethylbenzene, 1,3,5-
Pyridine, 4-methyl-
Cyclohexanone
Cyclohexanone
Pyridine, 3-methyl-
Pyridine, 2-methyl-
Triethylene glycol
dimethacrylate
Octadecanamide, N,N'-1,2-
ethanediylbis-
Source
OECD/SIDS/DE
OECD/SIDS/JP
ITC/6
OW/ODW
OECD/SIDS/BE
OECD/SIDS/CA
ITC/35
OECD/SIDS/BE
OECD/SIDS/BE
OPPT/NCP/ACR
OECD/SIDS/US
Year
Added
1992
1992
1990
1990 ,
1990
1992
1994
1990
1990
1992
1992
Year
Removed
1996
1996
1993
1995
1994
1996
1995
1994
1994
1995
1995
Removal
Rationale
VTA Testing
Program Completed
VTA Testing
Program Completed
FRM Testing
Program Completed
FRM Testing
Program Completed
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
Testing designation
withdrawn by ITC
Withdrawn from
OECD/SIDS program
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
Withdrawn from
OECD/SIDS program
Comments
Chemical remains-on MTL
because of additional testing
actions (see ITC Skin Absorption
Rate listing)
FRM = TSCA Section 4 Final Rule-Making
ECA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX II. CHEMICALS REMOVED FROM THE MASTER TESTING LIST
Page 7
CAS
Number
i 1 0-49-6
110-80-5
110-91-8
111-40-0
112-72-1
1 1 5-96-8
1 1 7-84-0
118-79-6
120-61-6
Chemical Name
2-Methoxyethyl acetate
Ethoxyethanol, 2-
Morpholine
Diethylenetriamine
1-Tetradecanol
Tris(2-chloroethyl)phosphate
Dioctyl phthalate
2,4,6-Tribromophenol
Dimethyl terephthalate
Source
OECD/SIDS/EU
OPPT/N
OECD/SIDS/UK
OECD/SIDS/NL
OECD/SIDS/US
ITC/23
OECD/SIDS/EU
OPPT/DF-OC
ITC/28
Year
Added
1994
1991
1992 -
1992
1992
1990
1994
1990
1992
Year
Removed
1995
1995 _
1994
1996
1994
1995
1995
1994
1993
Removal
Rationale
Withdrawn from
OECD/SIDS program
Testing requirement
withdrawn by OPPT
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
Withdrawn from
OECD/SIDS program
Testing designation
withdrawn by ITC
Withdrawn from
OECD/SIDS program
FRM Testing
Program Completed
Testing designation
withdrawn by ITC
Comments
-
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS listing)
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS listing)
Chemical remains on MTL
because of additional testing
actions (see OPPT Dioxins/Furans
in Organic Chemicals listing)
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS listing)
FRM = TSCA Section 4 Final Rule-Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX II. CHEMICALS REMOVED FROM THE MASTER TESTING LIST
PageS
CAS
Number
120-82-1
121-57-3
122-52-1
1 24-09-4
126-30-7
126-58-9 -
126-73-8
140-88-5
141-79-7
143-22-6
Chemical Name
1 ,2,4-Trichlorobenzene
Benzenesulfonic acid, 4-
amino-
Triethyl phosphite
1 ,6-Hexanediamine
Propanediol, 2,2-dimethyl-,
1,3-
1,3-Propanediol, 2,2'-
[oxybis-(methylene)
Tributyl phosphate .
Ethyl acrylate
Mesityl oxide
Triethylene glycol monobutyl
ether
Source
ITC/3
OECD/SIDS/DE
OECD/SIDS/DE
OECD/SIDS/CA
OECD/SIDS/JP
OECD/SIDS/SE
ITC/18
OPPT/NCP/ACR
ITC/4
OECD/SIDS/NL
Year
Added
1990
1990
1990
1992
1990
1990
1990
1992
1990
1990
Year
Removed
1994
1994
1994
1996
1996 ~
1996
1994
1995
1993
1994
Removal
Rationale
FRM Testing
Program Completed
Withdrawn from
OECD/SIDS program
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
VTA Testing
Program Completed
VTA Testing
Program Completed
FRM Testing
Program Completed
VTA Testing
Program Completed
FRM Testing
Program Completed
Withdrawn from
OECD/SIDS program
Comments
Chemical remains on MTL
because of additional testing
actions (see Hazardous Air
Pollutants Category and
OECD/SIDS listings)
-
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS listing)
FRM = TSCA Section 4 Final Rule-Making
ECA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX II. CHEMICALS REMOVED FROM THE MASTER TESTING LIST
Page 9
CAS
Number
143-33-9
147-14-8
1 56-62-7
294-62-2
482-89-3
504-60-9
527-60-6
584-03-2
682-09-7
693-23-2
793-24-8
Chemical Name
Sodium cyanide -
C.I. Pigment Blue 15
Cyanamide, calcium salt
(1:1)
Cyclododecane
3H-lndol-3-one, 2-(1,3-
dihydro-3-oxo-2H-indol-2-
ylidene}-! ,2-dihydro-
Pentadiene, 1,3-
Phenol, 2,4,6-trimethyl-
Butanediol, 1,2-
Tnmethylolpropane diallyl
ether
Dodecanedioic acid
1 ,4-Benzenediamine, N-(1,3-
dimethylbutyl
Source
ITC/27
OECD/SIDS/JP
OECD/SIDS/NO
OECD/SIDS/FR
OECD/SIDS/JP
OECD/SIDS/US
OECD/SIDS/NL
OECD/SIDS/JP ."
OECD/SIDS/DE
OECD/SIDS/US
OECD/SIDS/DE
Year
Added
1992
1990
1993
1990
1992
1990
1992
1990
1990
1990
. 1992
Year
Removed
1995
1996
1995
1994
1996
1996
1995
1996
1994
1996
1994
Removal
Rationale
EGA Testing
Program Completed
VTA Testing
Program Completed
Withdrawn from
OECD/SIDS program
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
VTA Testing
Program Completed
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
Withdrawn from
OECD/SIDS program
Comments
Chemical remains on MTL
because of additional testing
actions (see ATSDR SARA 104
Chemicals listing)
-- - - , ----- .
-
FRM = TSCA Section 4 Final Rule-Making
ECA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX II. CHEMICALS REMOVED FROM THE MASTER TESTING LIST
Page 10
CAS
Number
937-41-7
1163-19-5
1309-64-4
1 634-04-4
1680-21-3
1912-24-9
2156-96-9
2223-82-7
2402-79-1
2431-50-7
Chemical Name
Phenyl acrylate
Decabromodiphenyl ether
Antimony trioxide
Methyl tert-butyl ether
Triethylene glycol diacrylate
Atrazine
Decyl acrylate
/
Neopentyl glycol diacrylate
Tetrachloropyridine, 2,3,5,6-
Butene, 2,3,4-trichloro-, 1-
Source
OPPT/NCP/ACR
OPPT/DF-OC
ITC/4
ITC/20
OPPT/NCP/ACR
OECD/SIDS/CH
OPPT/NCP/ACR
OPPT/NCP/ACR
OECD/SIDS/US
OECD/SIDS/DE
Year
Added
1992
1990
,1990
1990
1992
1992
1992
1 992
1990
1990
Year
Removed
1995
1995
1994
1993
1995
1994
1995
1995
1996
1996
Removal
Rationale
VTA Testing
Program Completed
FRM Testing
Program Completed
VTA Testing
Program Completed
EGA Testing
Program Completed
VTA Testing
Program Completed
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
VTA Testing
Program Completed
VTA Testing
Program Completed
VTA Testing
Program Completed
Comments
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS, ITC/25
Brominated Flame Retardants and
, OPPT Dioxins/Furans in Organic
Chemicals listings)
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS listing)
FRM = TSCA Section 4 Final Rule-Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX II. CHEMICALS REMOVED FROM THE MASTER TESTING LIST
Page 11
CAS
Number
2720-73-2
4074-88-8
4162-45-2
4170-30-3 .
4461-52-3
4813-57-4
4986-89-4
5281-04-9
6419-19-8
7723-14-0
7784-18-1
Chemical Name
Potassium pentylxanthate
Diethylene gtycol diacrylate
TetrabromobisphenoJ A
bis(ethoxylate)
Crotonaldehyde
Methoxymethanol
Stearyl acrylate
Pentaerythritol tetraacrylate
D&C Red No. 7
Phosphoric acid, [nitrilotris-
(methylene)]tris-
Phosphorus, white
Aluminum fluoride
Source
OECD/SIDS/CA-
OPPT/NCP/ACR
OPPT/DF-OC
ITC/22
OECD/SIDS/JP
OPPT/NCP/ACR
OPPT/NCP/ACR
OECD/SIDS/JP
OECD/SIDS/UK
ITC/34
OECD/SIDS/NO
Year
Added
1990
1992
1990
1990
1992
1992
1992
1992
1990
1994
1993
Year
Removed
1994
1995
. 1993
1993.
1994
1995
1995
1996
1996
1996
1995
Removal
Rationale
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
FRM Testing
Program Completed
EGA Testing
Program Completed
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
VTA Testing
Program Completed
VTA Testing
Program Completed
VTA Testing
Program Completed
Testing designation
withdrawn by ITC
Withdrawn from
OECD/SIDS program
Comments
Chemical remains on MTL
because of additional testing
actions (see OPPT Dioxins/Furans
in Organic Chemicals listing)
/
Chemical remains on the MTL
because EPA is exploring
alternative testing mechanisms
FRM = TSCA Section 4 Final Rule-Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA, = Voluntary Testing Agreement
-------
INDEX II. CHEMICALS REMOVED FROM THE MASTER TESTING LIST
Page 12
CAS
Number
13048-33-4
13533-05-6
15625-89-5
16529-56-9
17831-71-9
24493-53-6
24800-44-0
25155-30-0
25265-77-4
25327-89-3
29171-20-8
Chemical Name
Hexamethylene glycol
diacrylate
Diethylene glycol
monoacrylate
Trimethylolpropane
triacrylate
3-Butenonitrile, 2-methyl-
Tetraethylene glycol
diacrylate
1,3-Propanediol diacrylate
Tripropylene glycol
Sodium dodecylbenzene
sulfonate
Propanoic acid, 2-methyl-,
monoester with 2,2,4-
trimethyl-1 ,3-pentanediol
Tetrabromobisphenol A, allyl
ether
6-Octen-1-yn-3-ol, 3,7-
dimethyl-
Source
OPPT/NCP/ACR
OPPT/NCP/ACR
N
OPPT/NCP/ACR
OECD/SIDS/FR
OPPT/NCP/ACR
OPPT/NCP/ACR
OECD/SIDS/JP
OECD/SIDS/NO
OECD/SIDS/US
OPPT/DF-OC
OECD/SIDS/CH
Year
Added
1992
1992
1992
1990
1 992
1992
1992
1993
1990
1990
1990
Year
Removed
1995
1995
1995
1994
1995
1995
1996
1995
1996
1994
1996
Removal
Rationale
VTA Testing
Program Completed
VTA Testing
Program Completed
VTA T.esting
Program Completed
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
VTA Testing
Program Completed
VTA Testing
Program Completed
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
FRM Testing
Program Completed
VTA Testing
Program Completed
Comments
^
i
Chemical remains on MTL
because of additional testing
actions (see OPPT Dioxins/Furans
in Organic Chemicals listing)
FRM = TSCA Section 4 Final Rule-Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX II. CHEMICALS REMOVED FROM THE MASTER TESTING LIST
Page 13
CAS
Number
29590-42-9
32534-81-9
32536-52-0
37853-59-1
37971-36-1
65996-92-1
67952-50-5
Chemical Name
Isooctyl acrylate
Pentabromodiphenyl ether
Octabromodiphenyl ether
Ethane, 1,2-bis(2,4,6-
tribromophenoxy)-
Butanetricarboxylic acid, 2-
phosphono-1,2,4-
Distillates (coal tar)
(1 -Methylethylidene)bis(4, 1 -
phenyleneoxyM 1 -methyl-2, 1 -
ethanediyl) diacrylate
Source
OECD/SIDS/US
OPPT/DF-OC
OPPT/DF-OC
OPPT/DF-OC
OECD/SIDS/DE
OECD/SIDS/EU
OPPT/NCP/ACR
Year
Added
1990
1990 -
1990
1990
1990
1994
1992
Year
Removed
1996
1995
1995
1996
1996 "
1995
1995
Removal
Rationale
VTA Testing
Program Completed
FRM Testing
Program Completed
FRM Testing
Program Completed
FRM Testing
Program Completed
VTA Testing
Program Completed
Withdrawn from
OECD/SIDS program
VTA Testing
Program Completed
Comments
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS, ITC/25
Brominated Flame Retardants and
OPPT Dioxins/Furans in Organic
Chemicals listings)
Chemical remains on MTL
because of additional testing
actions (see OECD/SIDS, ITC/25
Brominated Flame Retardants and
OPPT Dioxins/Furans in Organic
Chemicals listings)
Chemical remains on MTL
because of additional testing
actions (see ITC/25 Brominated
Flame Retardants and OPPT
Dioxins/Furans in Organic
Chemicals listings)
FRM = TSCA Section 4 Final Rule-Making
EGA = TSCA Section 4 Enforceable Consent Agreement
VTA = Voluntary Testing Agreement
-------
INDEX II. CHEMICALS REMOVED FROM THE MASTER TESTING LIST
Page 14
CAS
Number
84852-15-3
Chemical Name
Nonylphenol, 4-branched
Source
OPPT/NP
Year
Added
1992
Year
Removed
1993
Removal
Rationale
EGA Testing
Program Completed
Comments
Chemical remains on MIL
because of additional testing
acstions (see OECD/SIDS and
OPPT Nonylphenol listings
FRM = TSCA Section 4 Final Rule-Making -
EGA = TSCA Section 4 Enforceable Consent Agreement
, VTA = Voluntary Testing Agreement
------- |