United States
         Environmental Protection
         Agency
October-December
  1988
         Research and Development
&EPA  Research  Report
         Environmental
         Research
         Laboratory
         Athens, GA 30613

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 PRINT DATE: 01/30/89                                  CLIENT OFFICE     OAR	
 PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
 ******************************************
                      CODE  TITLE

 BUDGET SUB-ACTIVITY:  A101  AIR
              ISSUE:  F     Stratospheric Ozone
            PPA  (L):  75    STRATOSPHERIC OZONE

            PPA  (S):        STRATOSPHERIC OZONE
                 RC:  K     ERL ATHNS
            PROJECT:  42    Stratospheric Ozone Modification
    PROJECT OFFICER:  R. G. Zepp                             PHONE: FTS-250-3428
 ******************************************
             PLANNED START: 10/01/88     PLANNED END: 09/30/94
 ******************************************

 PROJECT DESCRIPTION:

     GOAL: Develop reliable methods of estimating the harmful exposure of ecosystems
     to UV-B radiation received under current & projected climatological conditions.
     RATIONALE: Evaluation of risk to ecosystems posed by decreased strat. ozone
     requires ability to estimate current & future expected doses of UV-B under
     different scenarios. Estimation procedures must account for physical
     dependencies & variations in concentrations of UV-B absorbing species in the
     environment as well as action spectra for harmful UV-B effects.
     APPROACH: Existing models will be modified to evaluate effects of decreased
     strat. ozone on UV-B exposure rec'd by organisms at land surface and in aquatic
     ecosystems. Models will be developed to estimate transport effects on UV-B
     exposure in aquatic ecosystems & effects of UV-B on geochemical cycles.
     These models will be field tested to evaluate their accuracy & to correct any
     deficiencies that may be revealed. This will be accomplished by measurements
     of solar irradiance reaching the ground under a variety of atmospheric
     conditions, & by experimental & field work to test & improve the estimation
     methods for hydrospheric transmissivity as a function of the concentration of
     light-absorbing constituents.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:

          0.5 FTE was allocated to ERL-Athens in FY89 for project 42.  Inhouse work
     has begun on exposure assessment methodologies.

          Activities during the quarter included the initiation of research on the
     development of an appropriate UV-3 chemical actinometer for evaluating exposure
     model predictions of solar UV-B irradiance reaching the earth's surface and
     downwelling into aquatic ecosystems.   Systems examined included actinometers
     based on the photoreactions of two ketones, valerophenone and 2-pentanone, in
     water.  Quantum yield and temperature studies were initiated during the
     quarter.   Results indicate that both actinometers  may be very useful.   Each has

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      a  reaction quantum yield near unity with virtually no temperature dependence
      between 10 and 40 degrees C.  For comparison, the temperature dependence for
      direct photolysis of the actinometer p-nitroanisole also was examined during
      the quarter; this photoreaction also was found to be little affected by
      temperature changes.

          Dr. Richard Zepp presented a paper on "Consequences of Stratospheric Ozone
      Depletion:  Actinometers for Evaluating Integrated UV-B Exposure" at the Annual
      Meeting of the Society of Environmental Toxicology and Chemistry, Washington,
      DC in November.

          No RSD funds have yet been authorized for expenditure by ERL-Athens
      on project 42.  Plans are being made, however, to fund an inhouse contract to
      provide laboratory personnel support, and to conduct a workshop on DV-B effects
      on geochemical processes in aquatic and terrestial ecosystems, probably to be
      held next spring at Woods Hole Oceanographic Institute.

          Planning for a field program to test our current models of light
      transmission in the hydrosphere, to be initiated during the spring in area
      lakes, was begun this quarter.  Personnel were identified and recruited, and
      general project objectives outlined.

          A currently used model of UVB transmission in the atmosphere (developed at
      the University of Chicago) was acquired and implemented on the Wyse
     workstation.  Analysis of this model will help define the upgrade path for the
     EXAMS atmospheric transmission model and may indicate some alternative models
      for additional study.  In preparation for expansion of the EXAMS program to
     accommodate DVB exposure analysis during this quarter, the suite of EXAMS
      implementations that had been developed to accommodate machine-specific feature
     of the various supported platforms (DSI board, MS-DOS, VAX, Siemens computers)
     were integrated into a single code set.  This was accomplished primarily by
     converting machine-dependent input/output routines into Fortran run-time
      formats controlled by datasets that incorporate the results of an analysis of
      the relevant machine dependencies.

STATUS AND SCHEDULE OF DELIVERABLES:

8219  DUE:  06/30/89  REVISED:           COMPLETED:
      Report:  Assessments of UV-B effects on photochemical transients in aquatic
      and terrestrial ecosystems.

8220  DUE:  09/30/89  REVISED:           COMPLETED:
      Report:   The Scientific Assessment of Existing Mathematical Models for
      Exposure of Terrestrial and Aquatic Biota to UV-B Radiation.

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 PRINT DATE: 01/30/89                                  CLIENT OFFICE     OAR	
 PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
 ******************************************
                      CODE  TITLE

 BUDGET SUB-ACTIVITY:  A101  AIR
              ISSUE:  G     2
            PPA  (L):  94    Ecological Effects of Global Climate Change

            PPA  (S):        Ecol. Glo. Climate
                 RC:  K     ERL ATHNS
            PROJECT:  34    Effects of Climate Change on Physicochexical Processes
    PROJECT OFFICER:  Richard G. Zepp                        PHONE: FTS-250-3145
 ******************************************
             PLANNED START: 04/01/89     PLANNED END: 09/30/98
 ******************************************

 PROJECT DESCRIPTION:

     GOAL:  Develop physicochemical process models to describe effects of climate
     changes on  emissions and dry deposition of greenhouse gases.
     RATIONALE:  Long-term climate changes will have important effects on the various
     physicochemical processes affecting natural emissions and dry deposition of
     radiatively important gases in land and water. Even small increases in flux of
     natural emissions may induce significant effects on global climate. Process
     models and  kinetic and equilibrium data are needed to assess such effects under
     various climate scenarios.
     APPROACH: Develop models for volatilization, sorption, chemical reactions and
     photochemical reactions involved in the natural emission and reposition of
     radiatively important gases. Physical process studies include partitioning
     between air and water, and water and soil, plus volatilization from water and
     soil. Temperature effects and, for soils, moisture and composition will be
     included. Chemical studies will focus on mechanisms and decay rates of ozone.
     Effects of  temperature and factors such as pH and chemical composition will be
     examined. The influence of photochemical processes (rates and mechanisms) will
     be determined. Trace metal, pH, and humic effects, and soil composition and
     origin will be included in developing relationships and models.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          No FTE's were allocated to ERL-Athens for this project for FY89,  and no
     R&D funds have yet been authorized for expenditure.  Plans are being made,
     however,  for both inhouse and extramural research once resources are available.

STATUS AND SCHEDULE OF DELIVERABLES:

     NO DELIVERABLES AVAILABLE

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PRINT DATE: 01/30/89                                  CLIENT OFFICE    OAR	
PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  A101  AIR
              ISSUE:  G     2
            PPA  (L):  94    Ecological Effects of Global Climate Change

            PPA  (S):        Ecol. Glo. Climate
                 RC:  K     ERL ATHNS
            PROJECT:  36    Biogenic Production of Nitrous Oxide and Methane in the Env.
    PROJECT OFFICER:  David Lewis                            PHONE: FTS-250-3358
******************************************
             PLANNED START: 04/01/89     PLANNED END: 09/30/98
******************************************

PROJECT DESCRIPTION:

     GOAL: Elucidate the relative contributions of bacterial production of nitrous
     oxide and methane among different environments (wetlands, soils, etc.), and the
     environmental factors affecting the production rates.
     RATIONALE:  Nitrous oxide and methane, major products of microbial metabolism,
     have great potential for adversely affecting the global climate. Global
     monitoring data indicate significant shifts in ambient concentrations of these
     gases in the atmosphere; therefore, an improved understanding of microbial
     production and of transformation of these gases is needed to provide
     capabilities for predicting future global climatic changes and guiding resource
     management.
     APPROACH:  A group of experts will be convened in a workshop to arrive at a
     consensus concerning which ecosystems and environmental parameters merit the
     highest research priority.  Laboratory and field studies will be conducted to
     elucidate which microorganisms and environments most significantly contribute
     to nitrous  oxide and methane production,  and what rate-limiting processes and
     environmental parameters most critically affect gas production rates.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          We have reviewed the literature, and formulated tentative research plans
     regarding biogenic contributions of nitrous oxide.  The organization of a
     workshop, and subsequent pursuance of high priority research topics  awaits
     funding of  this task.

          Recent research indicates that radiatively important trace gases other
     than carbon dioxide are also likely to influence global climate changes
     significantly.   These gases include methane,  nitrous oxide,  and tropospheric
     ozone.   In  addition,  carbon monoxide (CO),  although not itself radiatively
     important,  has  significant effects on the atmospheric concentration  of methane
     and tropospheric ozone.

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          The atmospheric concentrations of these gases are regulated, in part, by
     chemical and biological processes that occur in the biosphere.  Microorganisms
     in terrestrial and aquatic ecosystems produce large quantities of methane and
     nitrous oxide.  Carbon monoxide is produced through chemical and photochemical
     oxidation of natural organic matter in natural water bodies.  In addition,
     methane, nitrous oxide, and carbon monoxide are metabolized by microbiota and
     ozone is removed from the troposphere through reactions with vegetation, soil,
     and natural water.

          Our research focuses on developing generalizable mathematical
     relationships that can be used to model the effects of climate changes on
     biological and geochemical processes that are important sources and sinks of
     methane, nitrous oxide, carbon monoxide and tropospheric ozone in terrestrial
     and aquatic ecosystems.  The results are used in terrestrial and aquatic
     systems level mathematical models to predict the net fluxes of these gases as a
     function of various hypothesized land use or climate scenarios.  These studies
     will provide improved capabilities to determine both current and potential
     global contributions of biogeochemical versus anthropogenic sources of these
     trace gases as well as to evaluate the effects of various remediation options.

          We will discuss our current research efforts to provide a better
     assessment of contributions of microbial activities to global nitrous oxide,
     methane, and carbon monoxide concentrations through an improved understanding
     of (1)  the relative significance of different environments as sources and sinks
     and (2)  the environmental factors affecting production rates of these trace
     gases,  and well as our research efforts to improve the understanding of the
     geochemical processes in land and water on the production, decay, and biosphere
     -troposphere exchange of carbon monoxide, ozone, methane, and nitrous oxide.

          An abstract, "Sources and Sinks of Radiatively Important Trace Gases in
     the Biosphere" (Rogers, Burns, Zepp and Lewis),  was submitted upon invitation
     for presentation at the 1989 annual meeting of the Air and Waste Management
     Association, June 25-30.  Dr.  Rogers will present the paper.

STATUS AND SCHEDULE OF DELIVERABLES:

8232  DUE:  07/31/89  REVISED:           COMPLETED:
      Report:  Microbial processes  that influence emissions of radiatively
      important gases

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 PRINT DATE:  01/30/89                                  CLIENT OFFICE 	OWRS
 PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
 ******************************************
                      CODE  TITLE

 BUDGET SUB-ACTIVITY:  B101  WATER QUALITY
              ISSUE:  A     WQBA/PERMITTING
             PPA  (L):  10    WASTELOAD ALLOCATION MODELING AND SUPPORT

             PPA  (S):        WASTELOAD ALLOCATION
                 RC:  K     ERL ATHNS
             PROJECT:  06    Environmental Process Characterization
    PROJECT  OFFICER:  Richard G. Zepp                        PHONE: FTS-250-3428
 ******************************************
             PLANNED START: 10/01/80     PLANNED END: 09/30/90
 ******************************************

 PROJECT DESCRIPTION:

     GOAL:   Characterize key environmental processes (direct-indirect photolysis,
     redox,  sorption/desorption, metal speciation and transport) in water and
     sediment systems to improve exposure and risk assessment models.
     RATIONALE:  The role of inorganics in pollutant transformation by photolysis
     and the kinetics of redox reactions are inadequately understood for reliable
     use in  exposure assessment models. Sorption of ionizable organics also
     significantly affects pollutant transport.  Toxic metal speciation and
     transport needs further investigation since metal toxicity depends upon the
     species.
     APPROACH:  Using natural waters, sediments and reference materials, equations
     for the kinetics of materials will be tested. The studies will provide
     rate/equilibrium constants required in the models. Compounds and reaction
     conditions will be selected to permit generalizations about changes in
     molecular structure and environmental conditions. Studies will examine effects
     of inorganics on photochemistry, biotic influences on redox reactions in abiotic
     systems, binding characteristics of metals and humics,  and sorption processes
     of ionizable organics on sediments.  Distribution coefficients of metals will be
     determined for various solid substrates.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:


          Research was continued on the influence of light on the oxidation of
     organic substrates by manganese oxides. Kinetic studies of the oxidation of
     p-chlorophenol were conducted using  monochromatic radiation corresponding to
     the  maximum absorption of manganese  dioxide (336 nm).  The  pH dependence of the
     oxidation rate of p-phenylphenol in  manganese oxide  suspensions exposed to
     sunlight also was investigated. Studies of the influence of light on the
     oxidation of anilines by manganese oxides  were initiated;  the oxidation of
     p-chloroaniline  was examined.  Work on the  photoredox reactions of copper was
     also continued.  Quantum yields were  determined as a  function of pH for the

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     photoreduction of copper  (II) complexed by nitrogen ligands. Kinetic studies
     were conducted in sunlight for comparison. Two journal articles were submitted
     for publication during the quarter: "Hydrogen Peroxide Decay in Waters with
     Suspended Sediments: Evidence for Biologically Mediated Processes" and "Aquatic
     Humic Substances as Sources and Sinks of Photochemically Produced Transient
     Reactants."

          Studies of the effects of pH on the adsorption of anionic organic
     compounds to sediments have been initiated. Titration of a well characterized
     sediment using a pH-stat constructed here has shown that, between the ambient pH
     value of 7.8 to approximately pH 5.5, hydrogen ion activity can be controlled by
     the addition of acid (HC1) to within about 0.5 units. Titration of
     pentachlorophenol (POP, pKa equal to 4.8) between pH values of 7.8 and 4.0 in
     EPA 11 sediment (10 g sediment in 200 ml water) shows the concentration of
     pentachlorophenol in the aqueous phase to range from 80% of total added (at pH
     7.8) to approximately 4Z  (at pB 4.0). Between pH values of 3 and 4 no difference
     was observed in the partition coefficient. This is highly consistent with
     octanol-water partitioning data for POP in the same pH ranges. Further studies
     controlling the pH at higher values with the addition of base (NaOH) are
     anticipated, along with titration of other compounds having different
     properties.

          A paper on the homogeneous hydrolysis rate constants for selected
     chlorinated methanes, ethanes, ethenes and propanes has been drafted. This
     paper contains alkaline hydrolysis rate constants and activation parameters for
     15 chlorinated hydrocarbons. The data will provide a basis for developing a
     structure reactivity relationship for estimation of rate constants for other
     halogenated hydrocarbons. A draft journal article entitled "Hydrolysis of
     Chlorostilbene Oxide II. Hydrolysis in Aquifer Samples and in Sediment-Water
     Systems" contains results that provide support for a model that quantitatively
     describes abiotic hydrolysis in heterolytic systems.

          Kinetic studies of the degradation of Solvent Red 1 in anaerobic
     sediment-water systems show that the disappearance of the dye followed
     pseudo-first-order kinetics over two half-lives. The half-lives in two
     sediments were 94.6 and 67.9 hours.

          Studies progressed on the degradation of diphenyl- and dialkyl-N-nitroso-
     amines in anaerobic sediments. While diphenyl-N-nitrosoamine was degraded to
     diphenylamine with a half-life of 11.8 h, diethyl-, dipropyl-, and dibutyl-
     N-nitrosoamines were stable over a period of 14 days. Sorption studies indicate
     the dialkyl-N-nitrosoamines do not sorb to the sediment and that the
     diphenyl-N-nitrosoamine is only weakly sorbed. These results indicate that the
     dialkyl-N-nitrosoamines will be persistent and highly mobile in groundwater
     environments.

STATUS AND SCHEDULE OF DELIVERABLESt

8149  DUE: 06/30/89  REVISED:           COMPLETED:
      Report:  Sorption Processes for lonizable Organics on Sediments.

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PRINT DATE: 01/30/89                                  CLIENT OFFICE       OWRS
PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  B101  WATER QUALITY
              ISSUE:  A     WQBA/PERMITTING
            PPA  (L):  10    WASTELOAD ALLOCATION MODELING AND SUPPORT

            PPA  (S):        WASTELOAD ALLOCATION
                 RC:  K     ERL ATHNS
            PROJECT:  11    Biodegradation & Bioaccumulation Processes and Systems Res.
    PROJECT OFFICER:  David L. Lewis                         PHONE: FTS-250-3358
******************************************
             PLANNED START: 10/01/85     PLANNED END: 09/30/95
******************************************

PROJECT DESCRIPTION:

     GOAL:  Test the predictive accuracy and determine the applicability of
     microbial transformation rate coefficients for water quality models and
     evaluate bioaccumulation of toxicants in aquatic organisms in relation to
     thermodynaroic equilibrium processes.
     RATIONALE: This research is required to produce a reliable approach for
     predicting biologically mediated accumulation and degradation of pollutants to
     improve water quality and risk assessment models.
     APPROACH: Rate coefficents for microbial transformation of xenobiotic chemicals
     will be determined using microbial populations collected from lakes and streams.
     Bioaccumulation in organisms of varying size and lipid content and of different
     species will be determined using toxic chemicals that have varying partition
     coefficients. Coefficients determined in the laboratory will be compared with
     field data. Predictions based on thermodynamic calculations will be compared
     with experimental results.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:


          One paper, "Special applications of insect gut microflora in kinetic
     studies of microbial stubstrate removal rates" (Lewis & Said) was accepted for
     publication in the Journal of Environmental Toxicology and Chemistry.
     Laboratory microcosm studies regarding nitrification rates have been described
     in a manuscript "Nitrification by attached bacteria in an aquatic ecosystem"
     (Said, Lewis, Holm & Kollig),  which is being internally reviewed.

STATUS AND SCHEDULE OF DELIVERABLES;

8150  DUE: 08/31/89  REVISED:            COMPLETED:
      Internal report on microbial process highlights.

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10

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PRINT DATE: 01/30/89
PMS-060
CLIENT OFFICE
OWRS
             FIRST QUARTER STATUS REPORT ON FY*89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  B101  WATER QUALITY
              ISSUE:  A     WQBA/PERMITTING
            PPA  (L):  10    WASTELOAD ALLOCATION MODELING AND SUPPORT

            PPA  (S):        WASTELOAD ALLOCATION
                 RC:  R     ERL ATHNS
            PROJECT:  19    Wasteload Allocation Modeling and Support
    PROJECT OFFICER:  Tom Barnwell                           PHONE: FTS-250-3210
******************************************
             PLANNED START: 10/01/80     PLANNED END: 12/31/99
******************************************

PROJECT DESCRIPTION:

     GOAL: Assemble, modify or develop, and test arrays of wasteload allocation
     (WLA) and exposure assessment models for conventional and toxic pollutants for
     streams, rivers, lakes, and estuaries and provide OW with guidance and user
     assistance through the Center for Exposure Assessment Modeling (CEAM).
     RATIONALE:  Water quality-based NPDES revisions, WLAs, AWT assessments,
     use-attainability activities, and BMP selection by OW, Regions, States, and
     local governments require scientifically defensible modeling packages including
     documentation, data bases, training, and user assistance.
     APPROACH:  Gaps in existing WQ modeling packages will be identified through
     applied studies conducted in cooperation with OW and with ORD Laboratories.
     Developments or modifications will fill scientific gaps (e.g., metals
     speciation and sediment-water pollutant exchange routines) and improve
     ease-of-use (e.g., interactive model setups and microcomputer packages).  User
     assistance will include developing guidance documents, operating the CEAM to
     provide modeling packages/manuals/tapes and data bases on request, conducting
     training seminars and workshops as required, and providing hands-on user
     assistance as resources permit.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:


          Cooperative researchers at Tufts University revised a paper,  "DO Model
     Uncertainty with Correlated Inputs," based upon reviewer comments  and
     resubmitted it to the Journal of the Environmental Engineering Division.
     Continuing work on graphical presentation of uncertainty information is
     complete and a master's thesis describing the work is in preparation.

          Cooperative researchers at Cornell University continue to make good
     progress with the CORMIX model. Funding was received this quarter  from the
     Office of Water to complete work on this project.  Links between program models
     were completed this month and model validation,  including calibration of
                                        11

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coefficients, has begun. Abstracts have been submitted for the 1989 ASCE
Hydraulics and Environmental Engineering Division summer conferences and for
the International Association for Hydraulic Research Congress. Additional
funding was received to incorporate the work in a short course this summer.

     A LOTUS spreadsheet model was developed to reproduce the calculations by
the Environmental Defense Fund in their paper "Polluted Coastal Waters:  The
Role of Acid Rain."  A seminar reviewing procedures used in. the report was
presented.

     Testing, preparation of code, composition of support documentation, and
master file/diskette creation for the distribution version of WASP for VAX and
PC systems for release 4.14 is in  progress.

     Allen Medine conducted the course "Metal Contamination in Surface Waterst
Methods for Assessment and Control" for Region 8 and states December 13-14 in
support of the 304(1) program. Max Dodson, Region 8 Water Management Division
Director, sent a memo of thanks, declaring the workshop a
success.

     We continued migration of CEAM model distribution and registered user data
base from VAX to PC environment. We also began implementation of a CEAM
database for all CEAM training and model distribution activities.  Initial
preparation of CEAM's FY89 training courses began including selection of
tentative dates, course descriptions, and venus. Five courses are planned this
summer including:

     - QUAL2E with Uncertainty Analysis            July 10-14
     - Exposure and Bioaccumulation Models         July 24-28
     - MINTEQ                                    August 22-24
     - Estuarine Wasteload Allocation         September 11-15
     - RUSTIC                                 September 18-22

CEAM BBS and Model Distribution Statistics

      BBS Statistics:   Total Calls       477
                        New Users Added    70
                        Total Uploads      14
                        Total Downloads   270

      Model Distribution:

         Model         Diskette        BBS          Tape
         WASP4            27            16            0
         SWMM3            15             4            0
         HSPF9            23             0            3
         MINTEQ           57             3            1
         QUAL2E           44             6            1
         DYNTOX           10             7            0
         EXAMSII          20             3            2
         PRZM             16            11            3
         LC50              560
         SARAH             910
                                   12

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              FGETS            13             1            0
              GCSOLAR           730
              TOTAL            246     +     61      +    10  -  317

STATUS AND SCHEDULE OF DELIVERABLES:

7851  DUE: 07/31/88  REVISED: 07/31/89  COMPLETED:
      Report on Expert Advisor for CORMIX Model
      2/88 - delay to 7/89 a result of FY-88 Congressional Budget
      actions;  5/88 - transferred from B-101 A-15 during FY-89
      PPA devel. process and title change
                                        13

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14

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PRINT DATE: 01/30/89
PMS-060  ,
                                                      CLIENT OFFICE
OWRS
             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
BUDGET SUB- ACTIVITY ;
              ISSUE:
            PPA (L):

            PPA (S) :
                 RC:
            PROJECT:
    PROJECT OFFICER:
                      CODE  TITLE

                      B101  WATER QUALITY
                      A     WQBA/ PERMITTING
                      13    ECOLOGICAL RESEARCH WITH THE PEOPLE'S REPUBLIC OF CHINA

                            CHINA AGREEMENT - WQ
                      K     ERL ATHNS
                      20    Ecological Research with the Peoples Republic of China (PRC)
                      Roseraarie C. Russo                     PHONE: FTS-250-3134
                                                                    ********
**********************************
             PLANNED START: 10/01/84     PLANNED END: 09/30/90
******************************************

PROJECT DESCRIPTION;

     GOAL:  Participate jointly with PRC scientists and engineers in the refinement,
     application and field testing of environmental fate and exposure models for
     pollution control strategy development and assessment and in the study of
     environmental transformation processes.
     RATIONALE:  To support U.S. policy to provide scientific and technological
     cooperation with the PRC, specifically Annex 3 of the 1980 US-PRC Environmental
     Protection Protocol.
     APPROACH:  Via a combination of tailored model refinement and application
     projects and technology transfer workshops and symposia, the PRC will be
     helped to acquire and apply an array of appropriate environmental assessment
     methodologies for their use.  Athens ERL will design and monitor PRC field
     evaluations of selected models.  The technology developed and transferred will
     also be high priority for region/ state use in the U.S. Chemical and
     microbiological process characterization studies will also be conducted to
     elucidate the transformation and transport of metals and organics in surface
     and subsurface environments.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:


          Dr.  George Bailey attended the International Symposium on Environmental
     Life Elements and Health, November 1-5, 1988, in Beijing China.  He and Mr.  Lin
     Yuhuan each presented a scientific paper.  Two manuscripts were submitted for
     publication in the symposium proceedings.  Dr. Bailey presented seminars at the
     Research Center for Eco-Environmental Sciences,  Chinese Research Academy of
     Sciences, Beijing; the Chinese Research Academy of Environmental Sciences,
     Beijing and Shaanzi, and the Environmental Protection Bureau (National
     Environmental Protection Agency) ,  Xian. Dr.  Bailey presented a third paper
     based on Mr.  Lin's work at the American Society of Agronomy (ASA) National
     Meeting,  Anaheim,  California,  November 2 7 -Dec ember 2,  1988.
                                        15

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          Titles of manuscripts/presentations are:

          "Metal Interactions at Sulfide Mineral Surfaces:  Part II.  Adsorption and
     Desorption of Lanthanum," Lin Yuhuan, George W. Bailey and Alan T. Lynch
     (presented and submitted for publication in Symposium proceedings).

          "Metal Interactions at Sulfide Mineral Surfaces:  Part III.  Metal
     Affinities in Single and Multiple Ion Adsorption Reactions," Lin Yuhuan, George
     U. Bailey and Alan T. Lynch (presented and submitted for publication in
     Symposium proceedings).

          "Metal Interactions at Sulfide Mineral Surfaces:  Part IV.  Adsorption and
     Precipitation Reactions," Lin Yuhuan, George W. Bailey and Alan T. Lynch
     (presented at ASA National Meeting).

STATUS AND SCHEDULE OF DELIVERABLES;

8152  DUE: 09/30/89  REVISED:           COMPLETED:
      Internal Report:  Joint US-PRC Studies on Pollutant Transformation
      Processes, Metals Speciation and Assessment Models.
                                        16

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PRINT DATE: 01/30/89                                  CLIENT OFFICE       OWRS
PMS-060


             FIRST QUARTER STATUS REPORT ON FY*89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  B101  WATER QUALITY
              ISSUE:  C     WASTE WATER TREATMENT TECHNOLOGY
            PPA  (L):  46    IDENT. OF TOXIC CHEMICALS IN INDUSTRIAL EFFLUENTS

            PPA  (S):        TOXICS IDENT.
                 RC:  R     ERL ATHNS
            PROJECT:  02    Identify and Compile Data on Occurrence of Organics
    PROJECT OFFICER:  John M. McGuire                        PHONE: FTS-250-3185
******************************************
             PLANNED START: 10/01/82     PLANNED END: 09/30/92
******************************************

PROJECT DESCRIPTION:

     GOAL:  Identify and determine distribution of unlisted
     chemicals in industrial wastewaters. Compounds identifiable by empirical mass
     spectra matching and those eluding identification by this technique will be
     included.
     RATIONALE: As new industrial technology is implemented, different chemicals are
     introduced to wastewaters. Lists of regulated chemicals must be continually
     updated, otherwise the listing may contain compounds that occur infrequently
     and not contain other hazardous or toxic chemicals that, in fact, may occur
     more frequently. Determining the distribution of unlisted hazardous and toxic
     chemicals will permit maintenance of relevant lists for regulation.
     APPROACH: Computer programs will be developed and applied to search stored
     GC/MS data from industrial wastewater samples for nonpriority pollutants; mass
     spectra will be compared with library spectra for identification. Compounds
     that elude identification by spectra matching will be identified by reanalysis
     of samples using multispectral techniques (low res. electron impact MS, low
     res. chemical ionization MS, high res. MS, FTIR spec.). Computerized multi-
     spectral interpretation approaches will be developed to improve efficency.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


         As reported last quarter,  one list of target compounds for confirmation
     and another for multi-spectral identification of hits and misses have been
     generated from the study of POTW and organic industry GC/MS tapes from the
     Industrial Technology Division.  Due to the last minute arrival of retained
     extracts from 10 samples,  the list is being reconsidered before final
     multi-spectral analysis is completed.

STATUS AND SCHEDULE OF DELIVERABLES;

7579  DUE: 12/30/88  REVISED:  11/30/89  COMPLETED:
      Report on Multi Spectral  Identifications of MIS LIB Compounds.  (K)


      2/88 - delay to 11/89 a result  of FY-88  Congressional Budget
      actions

                                        17

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18

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PRINT DATE* 01/30/89                                  CLIENT OFFICE       ODW
PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  C104  DRINKING WATER
              ISSUE:  F     GROUNDWATER
            PPA (L):  82    Ground Water Methods, Information Transfer & Applications

            PPA (S):        GW MTHDS,INFO,& APPL
                 RC:  K     ERL ATHNS
            PROJECT:  22    Identify Unlisted Contaminants in Potential DW Sources
    PROJECT OFFICER:  John McGuire                           PHONE: FTS-250-3185
******************************************
             PLANNED START: 10/01/87     PLANNED END: 12/31/99
*********************** * * *****************

PROJECT DESCRIPTION;

     GOAL:  Identify and determine frequency of occurrence of unlisted compounds
     that may pose a hazard to human health in potential drinking water sources with
     emphasis on potential groundwater contamination so that the contaminants can be
     prioritized for health assessments.
     RATIONALE: The 1986 Amendments to the Safe Drinking Water Act require that
     lists of Recommended Maximum Contaminant Levels (RMCL) and monitoring
     requirements be published January 1, 1988, and every three years following for
     previously unregulated contaminants that pose a health risk in drinking water.
     Most monitoring programs identify only currently regulated compounds, therefore
     reanalysis of monitoring raw data is needed to identify unregulated compounds
     as candidates for listing.
     APPROACH:  Computer programs will be used to search GC/MS raw data from
     analyses of groundwater and other potential DW sources to identify unregulated
     compounds.  Mass spectra will be compared with library spectra for
     identification.  Compounds that cannot be identified by spectra matching will
     be identified by reanalysis of samples using multispectral techniques (low
     resolution electron impact MS, high resolution MS, Fourier transform IR
     spectrometry, chemical ionization MS).

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:


          The ether extracts of the pilot plant chlorination referred to last
     quarter showed the concentrations of most analytes to be too low for effective
     use of GC/FT-IR.  One GC peak present as a moderate level and corresponding to
     one of the unidentified, unchlorinated compounds in earlier Risk Reduction
     Engineering Laboratory studies was examined by GC/FT-IR, but no definite
     conclusions could be reached concerning its structure.

STATUS AND SCHEDULE OF DELIVERABLES:

8117  DUE: 08/31/90  REVISED:           COMPLETED:
      Report:  Ozonation Products of Drinking Water.

                                         19

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20

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 PRINT  DATE:  01/30/89                                  CLIENT OFFICE       OSW
 PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
 ******************************************
                      CODE  TITLE

 BUDGET SUB-ACTIVITY}  D109  HAZARDOUS WASTE
              ISSUE:  C     WASTE CHARACTERIZATION
             PPA  (L):  28    LAND DISPOSAL ASSESSMENT & EVALUATION OF OTHER MGMT SYSTEMS

             PPA  (S):        LAND DISPOSAL ASSESS
                 RC:  K     ERL ATHNS
             PROJECT:  03    Determine Chemical Transformation Pahways and Rates
    PROJECT  OFFICER:  Jackson Ellington                      PHONE: FTS-250-3197
 ******************************************
             PLANNED START: 10/01/85     PLANNED END: 12/31/99
 ******************************************

 PROJECT DESCRIPTION;

     GOAL:   Prepare transformation pathway profiles of RCRA regulated chemicals in
     order to provide data for environmental risk assessments.
     RATIONALE: Under Subparts B and C of RCRA Part 261, listed chemicals are being
     evaluated for their potential hazard to the environment when improperly
     treated, stored, transported or disposed of. The chemicals already listed under
     Subpart B are being subjected to mathematical modeling to determine acceptable
     concentrations in leachates for each listed chemical and its transformation
     products. Unlisted chemicals are being similarly evaluated under Subpart C as
     candidates for listing. Assessments of concentrations resulting from
     anticipated environmental conditions are necessary in order to determine
     acceptable leachate concentrations.
     APPROACH: Transformation processes, products and rates will be evaluated on a
     theoretical basis to identify those that are likely to be significant.  When the
     evaluation indicates a need for experimental confirmation of reaction rates or
     transformation products, appropriate experiments will be conducted. Results of
     the theoretical considerations and laboratory experiments will be published as
     transformation pathway profiles.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:


          A Research Brief was drafted entitled "Pathway Analysis of Chemical
     Hydrolysis for 14 RCRA Chemicals."   The brief identifies the pathway profiles
     of hydrolysis,  the intermediate and/or final products and rates of hydrolysis
     (including references)  of parents and intermediate  products.  A preliminary
     report of the pathway analysis was  provided to OSW.

          Laboratory measurement of second-order acid hydrolysis rate constants for
     seven substituted acetanilides are  in progress.   The rate constants will be
     correlated with molecular spectroscopic properties  to determine property-
     reactivity correlations.
                                         21

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          Dr. Ellington chaired a session on the RCRA/Superfund:  Toxics Monitoring
     Symposium at the Southeast Regional American Chemical Society Meeting held in
     Atlanta on November 9-11, 1988.

          An attempt was made to determine the photolysis product of N,N-diphenyl
     nitrosamine in water.  Due to possible instrumental effects, the compound was
     identified as either 9-nitroso-9H-carbazole or 9H-carbazole.  The uncertainty
     is due to the fact that the nitroso compound would decompose to the carbazole
     at the temperature of the 60 injection port.

          Two peaks from hydrolysis of 1,2-dichloroethane were identified.  One was
     identified as hydrogen chloride and the other ethylene glycol.

          The identities of 16 compounds to be used in degradation studies were
     confirmed by mass spectrometry.

          Hydrolysis products of phorate and phorate sulfoxide were identified.  The
     phorate sample showed both phorate and diethyl sulfide;  the sulfoxide sample
     showed no sulfoxide and only very small peaks corresponding to alkyl sulfides
     and thiols.  None of the observed compounds seems a likely hydrolysis product
     of either phorate or of the phorate sulfoxide.

STATUS AND SCHEDULE OF DELIVERABLESt

7950  DUE: 06/30/89  REVISED:           COMPLETED:
      Report on Hydrolysis Rate Constants for Enhancing Property-Reactivity
      Correlations.
                                         22

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 PRINT DATE:  01/30/89                                  CLIENT OFFICE       OSW
 PMS-060


              FIRST QUARTER STATUS  REPORT ON FY'89 PROJECT DESCRIPTIONS
                Office  of  Environmental Processes and Effects Research
                          ERL ATHNS: OCTOBER - DECEMBER 1988
 ******************************************
                       CODE TITLE

 BUDGET SUB-ACTIVITY:   D109 HAZARDOUS WASTE
               ISSUE:   C     WASTE  CHARACTERIZATION
             PPA (L):   28    LAND DISPOSAL ASSESSMENT & EVALUATION OF OTHER MGMT SYSTEMS

             PPA (S):        LAND DISPOSAL ASSESS
                 RC:   K     ERL ATHNS
             PROJECT:   07    Environmental Process Characterization - Metals
    PROJECT  OFFICER:   Arthur W. Garrison                     PHONE: FTS-250-3145
 ******************************************
              PLANNED START: 10/01/84     PLANNED ENDi 12/31/99
 ******************************************

 PROJECT DESCRIPTION;

     GOAL:   Provide data  on fate and transport of toxic metals for development of
     exposure assessment  models for implementing the Hazardous Waste Management
     Amendments, including evaluating waste management and treatment needs based on
     potential human health and environmental impacts.
     RATIONALE:  Current  activities, including RCRA Reauthorization requirements
     relative to Land Disposal Evaluation, demonstrate the lack of consistent
     exposure assessment  methods and data for determining the health and
     environmental impact  of various regulatory options.  Data on fate and transport
     of toxic metals are  needed for inclusion in models for exposure assessment,
     especially MINTEQ.
     APPROACH:  Thermodynamics and kinetics of sorption of metal cations,
     metal-ligand complexes and other metal species on soils, sediments, and aquifer
     substrates will be studied. Distribution coefficients will be determined using
     plasma  emission spectroscopy. Metal-ligand interactions will be studied using
     laser spectroscopy. Kinetic equations and equilibrium constants will be
     determined for use in exposure and risk models. Measurement, distribution, and
     significance of redox potential of aquifer systems will be studied.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:


          Major progress has been achieved by our University of Georgia cooperators
     in their application of a Gaussian distribution model for competitive metal
     binding with dissolved organics to fit their Lanthanide ion probe spectroscopic
     titration data. The paper "Characterization of Metal Binding Sites in Humic
     Acids by Lanthanide Ion Spectroscopy"  was accepted for publication in
     Analytical Chemistry, and a draft of another,  "A Study of the Competitive
     Binding of Protons and Metal Ions in Fulvic Acids by Lanthanide Ion
     Spectroscopy," is currently undergoing final revision before submission for
     journal publication.  Currently,  a draft of a paper on the binding of aluminum
     by dissolved organics in natural waters is being prepared.  At ERL-Athens,
     Lanthanide ion probe titration spectroscopy has been used successfully to  study
     the binding of lead by dissolved organic  matter.

          Georgia Institute of Technology (GIT)  cooperators have completed the  major
     portion of their matrix titration experiments using  total  dissolved organic


                                         23

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 matter from the Suwannee River (SRDOM),  carried out at three different ionic  •
 strengths. These data are needed to completely characterize the proton binding
 properties of SRDOM.  This information is essential for application of the
 Gaussian distribution model to the study of competitive metal binding.  These
 cooperators also have successfully isolated a substantial  quantity of SRDOM by
 the reverse osmosis technique they developed last  year.  About 10 grams  of SRDOM
 was give to ERL-Athens for use in our metal-organic binding studies.

      The possibility  of incorporating a  metal-organic  complexation component
 into MINTEQ,  the metal speciation model  currently  used for exposure assessment
 of toxic metals by OSW,  was discussed at a  joint meeting of U6A,  GIT,  and
 ERL-Athens cooperators in December.  There was a concensus  that development  of
 an algorithm for this component is quite achievable and should be the  immediate
 focus of the  cooperators.

      pH-dependent cationic adsorption profiles  for six aquifer material
 samples  were  completed this quarter.  At  present, modeling  the  adsorption  of
 anionic  species to aquifer materials  is  unsatisfactory.  Hence,  additional
 experimental  work soon will begin using  individual ionizable species. In
 December,  30  aquifer  material samples were  collected at  the joint ERL-Athens/
 USGS field testing site  near Globe, AZ for  further studies  of  metal-metalloid
 adsorption on aquifer solids.  Four out of five  attempted well  installations  at
 this site  were successful.

      A methodology has been developed using orthogonal functions  for
 deconvoluting mixed emission spectra  on  the ICP. In addition,  preliminary work
 on salt  concentration effects  on  ICP  nebulizer  efficiency has  led to the
 implementation of a scandium internal standard  procedure in the  ICP analytical
 protocol.  Previous dilution procedures often led to significant  sensitivity
 losses.

      Work  also has  been  completed  on  a cation exchange resin preconcentration
procedure  for  measuring  contaminant concentrations  at background  levels in
 groundwater.

      Technical assistance  (in conjunction with  the  ERL-Athens Assessment
Branch) was provided  tot 1) Ed Bates  (ERL-Cincinnati), Big  5 Wetlands Project,
and  2) EPA Risk Assessment Forum, on use of MINTEQA2 as  a tool for
investigating  the potential bioavailability of metals, especially  lead.

      Work continues at  the University of Guelph on desorption of various metals
found on bacterial  cell walls and cell wall-clay complexes.  A draft manuscript
entitled,  "Immobilization of Metallic Ions by Escherichia coli Envelope and
Bacillus subtilis wall - clay Mixtures" is undergoing internal review and
clearance.  Preliminary work has started at the University of Arkansas on metal
sorption—Cu(II), Cd(II), Ag(I) and La(III)—by three fungi:Aspergillus niger,
Rhodotorula ulzamae and Saccharomyces cerevisiae.
STATUS AND SCHEDULE OF DELIVERABLES:

8157  DUE: 08/31/89  REVISEDi           COMPLETED:
      Comprehensive Report on Applying Electrostatic Adsorption Theory to Natural
      Systems

8158  DUE: 03/31/89  REVISED:           COMPLETED:
      Report Defining Metal Complexation/Chelation Sites in Humic Materials


                                     24

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PRINT DATE: 01/30/89
PMS-060
CLIENT OFFICE
OSW
             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  D109  HAZARDOUS WASTE
              ISSUE:  C     WASTE CHARACTERIZATION
            PPA (L):  28    LAND DISPOSAL ASSESSMENT & EVALUATION OF OTHER MGMT SYSTEMS

            PPA (S):        LAND DISPOSAL ASSESS
                 RC:  K     ERL ATHNS
            PROJECT:  17    Environmental Process Characterization (Biological)
    PROJECT OFFICER:  John E. Rogers                         PHONE: FTS-250-3592
******************************************
             PLANNED START: 03/01/85     PLANNED END: 12/31/99
******************************************

PROJECT DESCRIPTION:

     GOAL:  Provide integrated (multimedia) methods and data for implementing the
     Hazardous Waste Management Amendments, including evaluating waste management
     and treatment needs based on potential human health and environmental impacts.
     RATIONALE: Current regulatory activities including,RCRA Reauthorization
     requirements relative to land disposal evaluation, are demonstrating the lack of
     consistent methods and data for determining the health and environmental impact
     of various regulatory options.  Integrated (multimedia) methods that
     accommodate knowledge of uncertainty are needed for more accurate and
     consistent decision-making on waste management options.
     APPROACH: Mechanisms of anaerobic biotransformations of xenobiotic chemicals
     will be characterized using kinetic concepts. Laboratory studies will be
     conducted to test these models and to identify environmental parameters that
     affect the rates and extent of the biotransformation processes.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          The effects of the composition of headspace gas on the degradation of
     2,4-dichlorophenol (DiCP) in anaerobic sediments were observed.   Reaction
     bottles containing 10 ml of sediment/water slurry (Ig dry sediment to 10 ml
     water) were amended with 10 mg/1 of 2,4 DiCP.  The initial headspace
     compositions were H2/N2 (5Z/95Z), C02/N2 (52/952), N2 (99.92)  or compressed
     air. Two experimental approaches were used. In the first, the  headspace gas was
     periodically exchanged with the initial gas composition during the incubation
     period and in the second the headspace gas was not exchanged over the entire
     incubation period.  The degradation rate was greatest in sediments in which the
     headspace composition was exchanged. In these studies,  degradation of 2,4 DiCP
     was complete by day 10 for C02/N2 and air and by day 14 for H2/N2 and N2. In
     reaction bottles in which the headspace was not exchanged, 2,4 DICP was absent
     in C02/N2 after 14 days and present in sediments with headspace  of air or N2
     after 17 days and in H2/N2 headspace bottles after 28 days.  The  results
                                         25

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      indicate that in all treatments the methane production  reached an exponential
      level before 2,4 DiCP degradation began.

         Reductive dechlorination of dichlorophenols was investigated in pond
      sediments from two sites in the Athens area.  Fresh Cherokee Pond sediment
      dechlorinated 2,4- and 3,4-dichlorophenol to monochlorophenols within 31 days,
      whereas fresh Bolton's Pond sediment dechlorinated 2,3-, 2,4-, and
      2,6-dichlorophenol to monochloro- products after approximately 17, 12, and 41
      weeks, respectively. Adapted Cherokee Pond sediments dechlorinated 2,4- and
      3,4-dichlorophenol within 4 days, whereas Bolton's Pond sediment was
      significantly slower, dechlorinating the 2,3-, 2,4-, and 2,6-dichlorophenol
      isomers within 3, 2, and 4 weeks, respectively. When 2,3-, 2,4-, 2,5-, 2,6-,
      3,4-, and 3,5-dichlorophenol were added individually to subsamples of the
      adapted sediments from both sites, differences in monochloro- products and
      dechlorination rates were observed. The differences in adaptation, product
      formation, and dechlorination rate appear to be site specific.

          The following two abstracts were submitted for the 1989 ASM Meeting to
     be held in New Orleans, LA, in May:  (1) Effect of Gas Phase Composition on
     Anaerobic Biodegradation of 2,4-Dichlorophenol (Howard, Hale & Struijs),
      (2) A Comparison of the Reductive Dechlorination of Dichlorophenols in Fresh
     and Acclimated Sediments from Two Ponds (Hale & Rogers).

          Laboratory experiments on the microbial degradation rates of methyl -
     chlorobenzoate,  methyl parathion, and 2,4-D butoxyethyl ester relative to a
     benchmark chemical, 2,4-D methyl ester, have been completed.  Kinetic data were
     obtained using biofilm, water, and sediment samples (separately) collected from
     field sites in Georgia and Florida.  Degradation rates varied widely,  depending
     on the test chemical and environmental sample.  However, degradation rates
     relative to the benchmark chemical degradation rates were constant.   These data
     will be used in a journal article "Microbial substrate removal rate
     coefficients relative to a benchmark chemical" (Newton, Lewis, Gattie).

          The UGA cooperative agreement has not been funded; therefore, we have no
     progress to report on our planned research on microbial adaptation to chemical
     degradation (Hodson) or biofilm species composition effects on microbial
     degradation and nutrient cycling (Shotts).

STATUS AND SCHEDULE OF DELIVERABLES;

7690  DUE:  07/31/89  REVISED: 11/30/89  COMPLETED:
      INTERNAL REPORT ON EQUATION FOR PREDICTING ANAEROBIC TRANSFORMATIONS WITHIN
      THE SATURATED ZONE

      3/87-transf.  from Ada to Athens to correct mistake on FY-87
      final version PPA's;  5/87-due date revised as a result of
      reprogramming of HW R&D resources to Wetlands program during
      FY-88 PPA planning process
      uut:  ut/ju/ay  KJSVISJSU:            uuruui&ir.u:
      Report on Evaluating the Utility of Current Methods for Estimating Anaerobic
      Degradation Rates for Use in Evaluative Models

      6/88  - moved from Y-105  B-02/33 to D-109 C-28/17
                                         26

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 PRINT DATE:  01/30/89                                  CLIENT OFFICE       OSW
 PMS-060


              FIRST QUARTER STATUS  REPORT  ON FY'89  PROJECT DESCRIPTIONS
                Office  of Environmental  Processes and Effects Research
                          ERL ATHNS:  OCTOBER - DECEMBER 1988
 ******************************************
                       CODE  TITLE

 BUDGET SUB-ACTIVITY:   D109  HAZARDOUS WASTE
               ISSUE:   C      WASTE  CHARACTERIZATION
             PPA (L)«   28    LAND DISPOSAL ASSESSMENT & EVALUATION OF OTHER MGMT SYSTEMS

             PPA (S):         LAND DISPOSAL ASSESS
                 RC:   K      ERL ATHNS
             PROJECT:   21    Multimedia  Modeling with Uncertainty Analysis
    PROJECT  OFFICER:   Lee A. Mulkey                          PHONE: FTS-250-3160
 ******************************************
              PLANNED START:  09/01/85      PLANNED END: 12/31/99
 ******************************************

 PROJECT DESCRIPTION:

      GOAL:   Provide multimedia methods  complete with uncertainty analysis
      capabilities  for  implementing the  Hazardous Waste Management Amendments,
      including  evaluating waiver petitions, listing procedures, and delisting
      petitions  based on  human health and  environmental impacts.
      RATIONALE:  Current regulatory activities, including RCRA Reauthorization
      requirements  relative to Land Disposal Evaluation, are demonstrating the lack of
      consistent methods  and  data for determining the health and environmental impact
      of various regulatory options.  Integrated (multimedia) methods that
      accommodate knowledge of uncertainty are needed for more accurate and
      consistent decision-making on waste management options.
      APPROACH:  The regulatory modeling system under development by OSW will be
      enhanced,  tested, and further developed to produce a comprehensive multimedia
      exposure assessement  system.  A major part of this approach will include data
      analysis, monte carlo programming,  and error analysis to derive uncertainty
      estimates.  Field testing and case study applications will be completed to
      further evaluate uncertainties.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:


          Dr. Dave Brown, Dr. Nick Loux, Jerry Allison,  Terry Allison and Lee Mulkey
     developed metal speciation and transport modeling results for lead from soils
     to human gastrointestinal tracts.  Dr.Brown presented the results at the Risk
     Assessment Forum Colloquium on Assessing Bioavailability of Lead and Other
     Metals December 7 and 8 in Washington, DC.  The effort was well received by the
     Colloquium attendees and will be followed-up with an outline of the effort that
     would be required to implement such an approach as  part of the overall  risk
     assessment scenario for lead in soils. If implemented,  this project should
     substantially reduce the uncertainties inherent in current risk assessment
     procedures.

          Effort this  quarter in  direct  support  of  OSW's development  of  a new rule
     for waste characteristics  included  the development of a new plan for research
     and model development activities geared for developing proposed  regulations for
     metals by December 1989  and  promulgating  final rules by July 1990.  Dr. Brown
     and Dr.  Loux met with headquarters  OSW technical staff December  8 to
     discuss  model  development  issues. A joint planning meeting  in Athens is  planned
     for February 2 and 3 to  finalize model development plans.

                                        27

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           A series  of four additional  monitoring  wells  were  installed  at  the Globe,
      AZ  mine waste  site  involved in  our  EPA/USGS  cooperative efforts for  obtaining
      data sets  to test the MINTEQA2  metal  speciat.ion/transport model.  Core samples
      from the bore  holes were  collected  and  returned to ERL-Athens  for
      characterization.

           Other OSW modeling support activities included:

      o Development  and testing of an overlayed version  of the Multimedia  Model for
       execution on PC.

      o The EPA  CML  code  was modified to  meet needs of the OSW transient case
       modeling project  and a  series of  modeling  runs was completed for
       conservative chemicals  to  be  covered  in the next round of rule  making.
       Results  of these  exercises will be  incorporated  in the upcoming rule.

      o Extensive  modeling  runs were  completed for G. Michaels of the Economic
       Analysis  Branch OPA/OPPE to help  evaluate  the impact  of the upcoming rule
       on  the pulp  and paper industry.

      o A new verison  of  MINTEQ  (MINTEQA2) was released  for distribution.  The new
       code was  first used in the context of the MINTEQA2 course presented in
       Boulder, CO  during  September. It  incorporates updated sorption  algorithms and
       a substantially revised preprocessor code  (PRODEFA2). The new sorption
       algorithm, based  on the diffuse layer model and augmented by a newly
       developed  database of intrinsic constants for Fe03 sorbents was tested on
       several  saturated zone matrix materials. The algorithm successfully predicted
       sorption of  several OSW metals, but failed for those metals that have
       predominantly  anionic solution species (Cr, As,  Se).

            Draft final  reports completed this quarter include:

     o Evaluation of  the Application of Geochemical Equilibrium Programs to
       Regulatory Assessment.

     o A Pilot Study on  the Selection of the Optimum Set of Components for
       Multicomponent Chemical Equilibrium Problems:   Selection,  Transformation,
       and Performance.

STATUS AND SCHEDULE OF DELIVERABLESi

8046  DUE: 06/30/89   REVISED:            COMPLETED:
      Report on Impact of Treayed Waste Forms on Exposure/Risk From Land Disposal
      pf Hazardous Waste

      8/87- added due to re-orientation of research program;  this
      replaces J7353-A which was deleted since the contents of
      that project were no longer needed by the program office

8159  DUE: 07/31/89   REVISED:            COMPLETED:
      User's Manual for  Site-Specific,  Multimedia Model for Ranking Closure
      Options at RCRA Land Disposal Operations.

8160  DUE: 08/31/90  REVISED:            COMPLETED:
      User's Manual for Model Defining Metal Species Transport in the Subsurface
                                        28

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PRINT DATE: 01/30/89                                  CLIENT OFFICE       OSW
PMS-060


             FIRST QUARTER STATUS REPORT ON FY*89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATMS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  D109  HAZARDOUS WASTE
              ISSUE:  C     WASTE CHARACTERIZATION
            PPA (L):  28    LAND DISPOSAL ASSESSMENT & EVALUATION OF OTHER MGMT SYSTEMS

            PPA (S):        LAND DISPOSAL ASSESS
                 RC:  K     ERL ATHNS
            PROJECT:  38    Environmental Process Characterization - Organics
    PROJECT OFFICER:  N. Lee Wolfe                           PHONE: FTS-250-3429
******************************************
             PLANNED START: 10/01/84     PLANNED END: 12/31/90
******** * * ********************************

PROJECT DESCRIPTION:

     GOAL:  Provide data on fate and transport of anthropogenic organic compounds
     for development of exposure assessment models for implementing the Hazardous
     Waste Management Amendments, including evaluating waste management and
     treatment needs based on potential human health and environmental impacts.
     RATIONALE:  Current activities including RCRA Reauthorization requirements
     relative to Land Disposal Evaluation demonstrate the lack of consistent
     exposure assessment methods and data for determining the health and
     environmental impacts of various regulatory options.  Data on fate and
     transport of anthropogenic organic compounds are needed for inclusion in models
     for exposure assessment.
     APPROACH:  Detailed laboratory kinetic studies will be conducted to describe
     soil mediated hydrolysis and abiotic redox transformation  reactions of
     organics as a function of pH and redox potential in the  sorbed and bulk
     aqueous phase of soil-water systems.  Molecular and  system variables that
     govern redox, sorption, and other processes will be related and quantified.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:


          Studies of the effects of pH on the adsorption of anionic organic
     compounds to sediments have been initiated.  Titration of a well characterized
     sediment using a pH-stat constructed here has shown that between the ambient pH
     value of 7.8 to approximately pH 5.5, hydrogen ion activity can be controlled
     by the addition of acid (HC1) to within about 0.5 units. Titration of
     pentachlorophenol (PCP, pKa equal to 4.8) between pH values of 7.8 and 4.0 in
     EPA 11 sediment (10 g sediment in 200 ml water)  shows the concentration of
     pentachlorophenol in the aqueous phase to range from 80% of total added (at pH
     7.8)  to approximately 4Z (at pH 4.0). Between pH values of 3 and 4,  no
     difference was observed in the partition coefficient. This is highly consistent
     with octanol-water partitioning data for PCP in the same pH ranges.  Further
     studies controlling the pH at higher values with the addition of base (NaOH)
                                        29

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     are anticipated, along with titration of other compounds having different
     properties.

          A draft paper on the homogeneous hydrolysis rate constants for selected
     chlorinated methanes, ethanes, ethenes and propanes has been written.  This
     paper contains alkaline hydrolysis rate constants and activation parameters for
     15 chlorinated hydrocarbons.  The data will provide a basis for developing a
     structure reactivity relationship for estimation of rate constants for other
     halogenated hydrocarbons of importance to OSW.  A draft jounal article entitled
     "Hydrolysis of Chlorostilbene Oxide II. Hydrolysis in Aquifer Samples and in
     Sediment-Water Systems" contains results that provide support for a model that
     quantitatively describes abiotic hydrolysis in heterolytic systems.

          A manuscript, "Reduction of Phorate Sulfoxide in Anaerobic Sediment
     Slurries," was submitted to Environmental Toxicology and Chemistry in November
     1988. This paper describes hydrolysis and redox processes in sediment and soil
     samples.  It shows that, at temperatures between 25 and 45 degrees C, reduction
     is the dominant transformation pathway, between 45 and 65 degrees oxidation
     dominates, and above 65 degrees hydrolysis dominates.  A second paper,
     "Characterization of Reducing Properties of Anaerobic Sediment Slurries Using
     Redox Indicators," also submitted to Environmental Toxicology and Chemistry in
     November, provides a basis for using redox indicators as a tool to describe the
     redox state of sediments, soils and aquifer materials.

          Kinetic studies of the degradation of Solvent Red 1 in anaerobic
     sediment-water systems show that the disappearance of the dye followed
     pseudo-first-order kinetics over two half-lives.  The half-lives in two
     sediments were 94.6 and 67.9 hours.

          Studies progressed on the degradation of diphenyl- and dialkyl-N-
     nitrosoamines in anaerobic sediments. While diphenyl-N-nitrosoamine was
     degraded to diphenylamine with a half-life of 11.8 hours, diethyl-, dipropyl-,
     and dibutyl-N-nitrosoamines were stable over a period of 14 days.  Sorption
     studies indicate the dialkyl-N-nitrosoamines do not sorb to the sediment and
     that the diphenyl-N-nitrosoamine is only weakly sorbed. These results indicate
     that the dialkyl-N-nitrosoamines will be persistent and highly mobile in
     groundwater environments.

STATUS AND SCHEDULE OF DELIVERABLES;

7355  DUE:  06/30/88  REVISED: 07/31/89  COMPLETED:
      REPORT ON PHOTODEGRADATION EVALUATION OF DIOXIN (2,3,7,8-TCDD) IN
      SOILS

      12/86 - delay to 9/88 a result of G-R-H tap 3/86;  2/88 - de-
      lay to 7/89 a result of FY-88 Congressional Budget actions;
      5/88 - transferred from D-109 D-54 during FY-89  PPA devel.
      process

7689  DUE:  12/30/88  REVISED: 04/30/89  COMPLETED:
      Report Describing the Kinetics of Redox Reactions  in Soil-water
      Environments.

      5/87 - due date revised during FY-88 PPA planning process
      as a result of reprogramming HW R&D resources into Wetlands
      program
                                        30

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 PRINT DATEt  01/30/89
 PMS-060
                                                      CLIENT OFFICE
OSW
              FIRST QUARTER STATUS  REPORT  ON  FY'89  PROJECT DESCRIPTIONS
                Office  of Environmental  Processes and Effects Research
                          ERL ATHNSi  OCTOBER  - DECEMBER 1988
 *****************************************
                       CODE TITLE
 BUDGET  SUB-ACTIVITY:  D109
               ISSUE:  C
             PPA  (L):  96
            PPA
                            HAZARDOUS WASTE
                            WASTE CHARACTERIZATION
                            Waste Futures and Aquatic Impacts
                (S):        HW Aquatic Impacts
                 RC:  K     ERL ATHNS
            PROJECT:  30    Assessment Methods for HW Characteristics and Constituents
    PROJECT OFFICER:  Thomas Barnwell                        PHONE: FTS-250-3175
******************************************
             PLANNED START: 01/31/88
                                         PLANNED END: 09/30/95
**********************************
PROJECT DESCRIPTION;

     GOAL:  Develop methods and models to predict  (1) impact of future waste forms
     and regulatory levels on aquatic life and habitats and (2) regulatory
     thresholds for aquatic life and habitat impacts.
     RATIONALE: OSW is redefining the waste characteristics that will set the future
     form, concentrations, and treatment levels for hazardous wastes. Little
     consideration has been given to aquatic impacts except as an exposure pathway
     to humans. Among these are organism toxicity, habitat alteration from oily
     wastes and sludges/slurries, and damages from flooded facilities. No methods
     exist to estimate the likelihood and consequences of future waste problems.
     Methods to properly define "safe" waste futures are not available for aquatic
     environmental impacts.
     APPROACH: Relationships among future waste forms (component chemical
     concentration levels, treatment systems, oily wastes, disposal systems).
     release modes/rates and aquatic impacts will be identified and modeled within
     the OSW framework for defining appropriate waste characteristics. Data gaps
     will be identified and filled, and developed methodologies will be tested.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:
          This task is concerned with the development and validation of biological
     procedures that can be effectively used as part of monitoring efforts at
     hazardous waste sites.  The procedure being evaluated is based on an
     ERL-Corvallis test for the bioassessment of waste site locations.  The method
     has been tested at actual waste sites and found to be one of the better
     screening techniques for detecting the presence of potentially hazardous
     compounds.  The current evaluation (and the subject of this quarterly report)
     will establish the data quality that can be achieved within a single
     laboratory,  it will provide a basis for deciding whether the procedure merits
     collaborative testing and will more clearly define the method's potential for
     inclusion as part of an operational monitoring network.

          The Chlorophyta Assay Using Soil and Sample Material is used to assess the
     potential toxicity of soil samples such as might be collected in the vicinity
     of hazardous waste sites.  Water is added to individual soil samples and the
     resulting eluate is tested for toxicity using green algae (Selenastrum
     capricornutura).  Since an aqueous eluate is intially acquired from the original

                                         31

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      soil  sample,  and  since  this eluate  is  filtered and diluted prior to toxiclty
      testing,  the  procedure  does not really address nonwater soluble chemicals nor
      does  it test  for  the presence of volatile compounds.  In addition, problems
      associated with the collection of soil samples (e.g., representative sampling
      of a  waste site area) are not addressed.  Based on the ecological importance of
      unicellular algae, however, this relatively simple technique can provide an
      environmental hazard assessment for those chemicals that are, in fact, the
      compounds most likely to be transported to surface and ground waters.

           The method protocol has been reviewed, revised, and reviewed a second time
      as steps toward achieving a "consensus* method.  Water eluates were also taken
      from  different types of soil, and tested using Selenastrum Sp., before a clay
      loam  soil (characterized as being 221  sand, 51% silt, and 27% clay) was
      selected for use  during the evaluation.  After the soil selection was made, a
      suitable quantity of soil (approximately 275 kg) was collected so that enough
      soil  would be available for the entire single laboratory effort.  The soil was
      thoroughly homogenized, first by grinding, and then by being placed in a
     mechanical soil mixer and mixed for several hours.  A ruggedness test, to
      identify procedural variables that must be carefully controlled, also was
     conducted.

           If the Chlorophyta procedure is "rugged" it will not be susceptible to the
      inevitable,  modest departures in routine and the final test result will not be
     altered by these  slight variations.   However, moderate procedural variations
     definitely altered the final Chlorophyta test result when they occurred at
     certain critical  steps.  Steps that must apparently be followed strictly as
     written concern the amount of water added to the dry soil sample, the pH of the
     resulting soil eluate that is actually used during the assay, and the specific
     eluate concentrations (dilutions)  prepared for the assay dilution series.  The
     Chlorophyta protocol has consequently been revised to emphasize strict
     adherence to these critical instructions.

          The SARAH2 computational algorithms were completed this quarter.   Work
     began on development of a new user interface using the AIDE user interface
     toolkit developed under the Ecorisk research program.  This interface should be
     completed in early February 1989.   Implementation of the Monte Carlo shell is
     on hold pending completion of the  new interface.

          A review of flooding regulations for solid waste management was completed
     by Aqua-Terra Consultants and delivered to Mark Schuknicht of OSW.

          A report on feasibility of incorporation of the Habitat Suitability Index
     (HSI)  in SARAH is  under review by  the authors (Aqua-Terra)  and also will be
     complete by  the end of January.

          Significant technical support in support of hazardous  waste
     characterization and aquatic impacts included:


          o  Provided Bill Vocke, OSW Economic Analysis Branch,  information on the
     oily waste model and CEAM work on wood-preserving waste for OSW and Superfund.

          o  Sent Dr. Shin Chang, New Jersey Department of Environmental Protection,
     a set of chemical hydrolysis transformation rates, sorption coefficients, and
     water solubilities for use in landfill model in concentration based listing
     program.

STATUS AND SCHEDULE OF DELIVERABLES;

     NO DELIVERABLES AVAILABLE

                                           32

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PRINT DATE: 01/30/89
PMS-060
                                                      CLIENT OFFICE
OPP
             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
BUDGET SUB- ACTIVITY:
              ISSUE:
            PPA (L):

            PPA (S):
                 RC:
            PROJECT:
    PROJECT OFFICER:
                      CODE  TITLE

                      E104  PESTICIDES
                      D     ECOLOGY: TRANSPORT /FATE /FIELD VALIDATION
                      07    GROUNDWATER: PEST. CONTAMINATION AND PROCESS STUDIES

                            PEST. GROUNDWTR RES.
                      K     ERL ATHNS
                      24    Validation of Predictive Techniques for Environ. Exposure
                      David S. Brown                         PHONE: FTS-250-3310
******************************************
             PLANNED START: 04/01/81     PLANNED END: 09/30/90
******************************************

PROJECT DESCRIPTION;

     GOAL:  Refine, parameterize, and evaluate via field and other studies the
     capability of single and multimedia pesticide exposure models that predict the
     multimedia and intermedia transport and fate of pesticides, especially through
     soils (including an evaluation of their leaching potential), sediments, and
     other porous media to ground and surface waters.
     RATIONALE:  Optimum pesticide regulation requires field-evaluated assessment
     techniques to assure that scientifically defensible decisions are made using
     cost-effective data specifications and assessment methods.
     APPROACH: As single and multimedia pesticide exposure assessment packages are
     developed or assembled from SOA components on application/drift, runoff,
     leaching, surface stream, river and lake simulation, etc., and become
     operational, they will be systematically evaluated via application to "real
     world" OPP and state problems and via retrospective comparison studies. Limited
     special field studies also will be initiated in concert with OPP, states,
     Regions, and other agencies to generate required data bases to test either
     complete model packages or specific components. Current emphasis is on the
     Dougherty Plain leaching study.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          All monitoring equipment was removed from the Dougherty Plain test site
     and the site was released to the cooperating farmer. An additional set of 597
     soil samples were taken for bromide tracer analysis from sidewalls, the large
     excavations developed in removing monitoring test equipment. Analysis of both
     soil and water samples for bromide tracer continued during the quarter. A total
     of 3700 bromide samples have been analyzed to date for use in testing and
     calibrating the pesticide transport codes PRZM/RUSTIC.

          A manuscript entitled "A Method for Testing Whether Model Predictions Fall
     within a Prescribed Factor of True Values with Application to Pesticide
                                        33

-------
     Leaching", was completed during the quarter and submitted to Water Resources
     Research.  This work describes a quantitative method for evaluating model
     performance at the field level and is viewed as a signifcant new contribution
     in the field of model testing.  Generally, the technique should be applicable
     to a variety of environmental pollutant transport and transformation models.

          Plans were developed for a multiagency cooperative field research
     project on pesticide leaching at a new field site near Plains, 6A.  Three
     agencies—EPA, USDA and USGS—will cooperate at the site in an effort
     to maxmize efficiency and reduce costs of model testing.

          Mr. Charles Smith was appointed as the laboratory representative for the
     Environmental Monitoring and Assessment (EMAP) Project Agroecosystem Work Group
     and attended the planning workshop held in Chicago, October 24-27, 1988.
     Substantial follow-up planning activities also have taken place during the
     quarter.

STATUS AND SCHEDULE OF DELIVERABLES;

7661  DUE: 09/30/89  REVISED:           COMPLETED:
      Final Dougherty Plain Report Including Pesticide Ground Water Threat
      Assessment Method

      5/88- tille change during FY-89 PPA devel.

7664  DUE: 06/30/89  REVISED:           COMPLETED:
      Project Report on Soils Data Based for RUSTIC Model (Linked PRZM-Groundwater
      Model)

      5/88 - title change

8196  DUE: 12/31/90  REVISED:           COMPLETED:
      Report on Testing RUSTIC Model Using Selected Data Bases
                                        34

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PRINT DATE: 01/30/89                                  CLIENT OFFICE       OPP
PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  E104  PESTICIDES
              ISSUE:  D     ECOLOGY: TRANSPORT/FATE/FIELD VALIDATION
            PPA (L):  08    PREDICTIVE TECHNIQUES FOR ENVIRONMENTAL EXPOSURE

            PPA (S):        DEVELOP PRED. TECH.
                 RC:  K     ERL ATHNS
            PROJECT:  14    Pesticide Process Characterzation
    PROJECT OFFICER:  Arthur W. Garrison                     PHONE: FTS-250-3145
******************************************
             PLANNED START: 10/01/87     PLANNED END: 12/31/99
******************************************

PROJECT DESCRIPTION:

     GOAL:  Characterize key environmental processes that lead to transformation or
     transport of pesticides in soil, sediment, water and related environments;
     apply this information to improve predictive techniques for environmental
     exposure.
     RATIONALE:  Transformation processes such as redox reactions in anoxic
     environments (some sediments, subsurface zones), photolysis on soil and plant
     surfaces and in the vapor state above application areas, and sorption,
     especially of irrigable pesticides, are not characterized to the extent
     necessary to account for pesticides loss to the environment.  Degradation
     products are not identified for many processes.
     APPROACH:  Laboratory studies using natural waters,  soils, sediments, and
     reference materials will be conducted to test proposed equations for pesticide
     transformation kinetics and sorption equilibria.  These studies will provide
     rate and equilibrium constants required for exposure predictive models.
     Compounds and reaction conditions will be selected to permit generalizations
     about changes in molecular structure and environmental conditions.  Initially,
     photochemical transformations on soil surfaces and sorption of water soluble
     (ionizable) pesticides to soils and sediments will be emphasized.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          Studies of the effects of pH on the adsorption of anionic organic
     compounds to sediments have been initiated.  Titration of a well characterized
     sediment using a pH-stat constructed here has shown that, between the ambient pH
     value of 7.8 to approximately pH 5.5, hydrogen ion activity can be controlled by
     the addition of acid (HC1) to within about 0.5 units. Titration of pentachloro-
     phenol (PCP,  pKa equal to 4.8) between pH values of 7.8 and 4.0 in EPA 11
     sediment (lOg sediment to 200ml water) shows the concentration of pentachloro-
     phenol in the aqueous phase to range from 80% of total added (at pH 7.8)  to
     approximately 4Z (at pH 4.0). Between pH values of 3 and 4, no difference was
                                        35

-------
     observed in the partition data for POP in the same pH ranges. Further studies
     controlling the pH at higher values with the addition of base (NaOH) are
     anticipated, along with titration of other compounds having different
     properties.  Aqueous phase metals have been measured by ICP to assess the
     effects of the pH changes on the dissolution and precipitation of inorganic
     species and their possible relationship to organic anion partitioning.

          A manuscript, "Reduction of Phorate Sulfoxide in Anaerobic Sediment
     Slurries," was submitted to Environmental Toxicology & Chemistry in November
     1988.  This paper describes hydrolysis and redox processes in sediment and soil
     samples.  It shows that at temperatures between 25 to 45 degrees C reduction is
     the dominant transformation pathway, between 45 and 65 degrees C oxidation
     dominates, while above 65 degrees C hydrolysis dominates.

          A second paper, "Characterization of Reducing Properties of Anaerobic
     Sediment Slurries Using Redox Indicators," also submitted to Environmental
     Toxicology & Chemistry in November, provides a basis for using redox indicators
     as a tool to describe the redox state of sediments, soils and aquifer
     materials.

STATUS AND SCHEDULE OF DELIVERABLES;

8197  DUE» 06/30/90  REVISED:            COMPLETED:
      Report on Sorption of Water Soluble Ionic Pesticides to Soils and Sediments.
                                        36

-------
PklNT DATE: 01/30/89
PMS-060
CLIENT OFFICE
OPP
             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  E104  PESTICIDES
              ISSUE:  D     ECOLOGY: TRANSPORT/FATE/FIELD VALIDATION
            PPA (L):  08    PREDICTIVE TECHNIQUES FOR ENVIRONMENTAL EXPOSURE

            PPA (S):        DEVELOP PRED. TECH.
                 RC:  K     ERL ATHNS
            PROJECT:  25    Predictive Techniques for Environmental Exposure
    PROJECT OFFICER:  David S. Brown                         PHONE: FTS-250-3310
******************************************
             PLANNED START: 10/01/81     PLANNED END: 12/31/99
******************************************

PROJECT DESCRIPTION:

     GOAL:  Provide long term, short turnaround, or direct single or multimedia
     exposure assessment technology assistance to OPP.
     RATIONAL:  OPP occasionally needs quick turnaround, customized model
     development and application assistance for high priority regulatory actions
     mandated under FIFRA.  This effort provides a focused, coordinated body of
     expertise comprised of ORD and OFP agency personnel augmented by extramural
     specialists to meet this need on demand.  It also provides the expertise to
     develop needed long term multimedia, site-specific exposure assessment modeling
     techniques.
     APPROACH:  Develop or assemble single and multimedia pesticide exposure
     assessment packages from SOA components and apply them to high priority OPP
     regulatory problems.  Athens ERL also is responsible for generating needed
     agronomic/management scenarios for non-irrigated crop applications and
     reporting requirement to OPP.  Close coordination with similar exposure/risk
     model development activities for OTS and OW are envisioned and required, e.g.
     PMN assessments.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:


          Efforts during the quarter focused on completion and documentation of the
     code linkages required in assembling the new linked root zone, vadose zone,
     saturated zone pesticide transport model RUSTIC. A work assignment for
     additional testing of the linked code and beta testing versions was distributed
     to three cooperators. So far some differences have been found in the VAX and
     Prime versions and these problems are undergoing further investigation.

          A series of 40 Pesticide Root Zone Model (PRZM)  input scenarios were
     developed and provided to CAD West for the Sun Computer Development Project.

          Ongoing technical assistance efforts to the PRZM Users Group continued
                                        37

-------
     during the quarter.  A variety of  technical,  scientific,  and.U',Qmpuflsc-related
     questions were handled by phone.

          Technical assistance was provided  to  OPP,  as  requested %• Gafi-Ssaarita® JEiden,
     concerning technical approaches to modeling behavior of pestdJedMksj u*sedt in, ship
     paints in the New York, San Diego  Bay and  Norfolk  harbors.

          Review, evaluation and testing of  the overlay structure;  for EG;
     implementation of RUSTIC is underway.

STATUS AND SCHEDULE OF DELIVERABLES;

     NO DELIVERABLES AVAILABLE
                                         38

-------
PRINT DATE: 01/30/89                                  CLIENT OFFICE       OPP
PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  E104  PESTICIDES
              ISSUE:  I     ECOLOGY: ECOTOXICITY AND RISK ASSESSMENT
            PPA  (L):  13    DEVELOPMENT OF INTEGRATED RISK ASSESSMENT MODELS

            PPA  (S):        INTEGRATED RISK ASS.
                 RC:  K     ERL ATHNS
            PROJECT:  26    Risk Assessment Methods for FIFRA
    PROJECT OFFICER:  David S. Brown                         PHONE: FTS-250-3310
******************************************
             PLANNED START: 10/01/85     PLANNED END: 12/31/99
******************************************

PROJECT DESCRIPTION:

     GOAL:  Develop, refine and extend existing terrestrial and aquatic fate,
     transport and effects models to include hazard impact, subroutines and data for
     environmental risk assessments (RA) for the labeled use of pesticides.  Results
     must be expressed in terms of probability of impact and frequency of occurrence
     and duration.
     RATIONALE:  Proven, operational environmental RA models are needed to evaluate
     registration requests for new pesticides and for re-registration and label
     changes (e.g, new uses) of existing compounds under FIFRA.
     APPROACH:  Existing unsaturated/saturated zone soil transport models, proven
     runoff-surface water pesticide codes, appropriate ground water codes, and
     related air transport models will be combined to produce SOA exposure
     assessment model frameworks.  These will then be linked with available effects
     models to produce defensible RA methodologies for OPP.  As completed, the risk
     assessment packages will be tested and evaluated, especially in terms of
     probabilities and uncertainties associated with real world problems.  Close
     coordination will be required with CERL, RSKERL, AREAL and the aquatic fate
     research at AERL.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:


          Mr.  Jeff Scarbrough is developing a ground spray application module for
     the new Terrestrial Ecosystem Exposure Assessment Model (TEEAM)  and has been
     working to eliminate some minor "bugs" discovered in the present aerial spray
     application code.

          Mr.  Mark Cheplick carried out further development and testing of TEEAM
     during the quarter and has begun a series of sensitivity tests initiated in the
     hope of finding appropriate ways to streamline the code.

          A draft report outlining results of initial TEEAM sensitivity tests was
                                        39

-------
     completed is vmder review. The report is entitled "Sensitivity Analysis of the
     Terrestrial Ecosystem Exposure Assessment Model."

STATUS AND SCHEDULE OF DELIVERABLES;

8129  DUE: 02/28/89  REVISED:           COMPLETED:
      Users Manual and User Interface Toolkit for Exposure Assessment Models


8130  DUE: 08/31/89  REVISED:           COMPLETED:
      Report:  Sensitivity Analyses and Preliminary Testing of the Terrestrial
      Ecosystem Exposure Assessment Model

8131  DUE: 08/31/90  REVISED:           COMPLETED:
      Users Manual for Updated TEEAM Model
                                        40

-------
PRINT DATE: 01/30/89                                  CLIENT OFFICE 	OTS
PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  L104  TOXICS
              ISSUE:  D     ECOLOGY: TRANSPORT/FATE/FIELD VALIDATION
            PPA (L):  09    DEVELOPMENT OF VALIDATED EXPOSURE ASSESSMENT METHODOLOGIES

            PPA (S):        EXPOSURE ASSESSMENT
                 RC:  K     ERL ATHNS
            PROJECT:  12    Development of EcoRisk Exposure Models
    PROJECT OFFICER:  Craig Barber                           PHONE: FTS-250-3U7
******************************************
             PLANNED START: 10/01/87     PLANNED END: 12/31/99
******************************************

PROJECT DESCRIPTION;

     GOAL:  Provide modeling approaches for evaluating exchanges of toxic
     chemicals between aquatic organisms and their environment.
     RATIONALE:  The evaluation and prediction of risk from toxicants must be based
     on sound methods for assessing the uptake, distribution, and effects in target
     organisms.  Testing all chemicals would be impossible and models must be
     developed that can use readily available chemical parameters to make
     predictions.
     APPROACH: Exchange models will be developed to provide estimates of body
     burdens of representative chemicals. Models will be based on thermodynamic
     principles and raorphometric characteristics of organisms as well as on
     consideration of route of exposure (water, food, or benthic sediments).
     Assessments can then take into account multiple sources of contaminants and
     also be extended to include ecological significance or effects. Physiological
     response depends on the chemical concentration in the organisms rather than
     that in the environment and the exchange models will be linked to toxicokinetic
     models to predict effects. Laboratory experiments will be conducted to test
     underlying hypotheses, and other factors involved will be identified.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:


          An article entitled "Modeling Bioaccumulation of Organic Pollutants in
     Fish with an Application to PCBs in Great Lake Salmonids" was submitted to
     the Canadian Journal of Fisheries and Aquatic Sciences.

          Work was begun to extend FGETS'  capabilities so that bioaccumulation of
     ionizable organic chemicals can be simulated.  Because, in the absence of
     specific transport mechanisms, only the neutral species of an ionizable
     chemical is exchanged across biological membranes,  it was initially thought
     that this extension to FGETS would simply require computational algorithms to
     estimate the  water concentrations of the exchangeable species.  A compilation of
                                        41

-------
     a small data set of published studies on the bioaccumulation of various
     chlorophenols indicated that this logic was incorrect because uptake rates
     predicated by FGETS adjusted for effective concentration were one or two orders
     of magnitude lower than observed values. Such underestimation could result
     either because the ionized species is also exchanged or because the transport
     conductance of the neutral species of an ionizable chemical through the
     interlamellar water of a fish's gills is enhanced by the chemical's
     dissociation reaction. The latter explanation is currently being investigated
     by constructing analytic solutions to the partial differential equations that
     describe mass diffusion with forced convection in flat channels under boundary
     conditions that are thought to emulate those associated wtih ionizable
     chemicals.

          Early in December, Dr. David Randall and Dr. Larry Fiddler visited
     ERL-Athens to discuss how their studies in fish respiratory physiology might
     interface or help support our bioaccumulation modeling. It was clear that their
     work on ammonia and carbon dioxide exchange across fish gills was of immediate
     importance to our current work involving ionizable chemical because carbon
     dioxide excretion alters the pH and hence the concentration of the neutral
     species of an ionizable chemical in the interlamellar water of the gill.  It
     would be desirable and advantageous to foster this continued interaction if
     R&D resources are available.

STATUS AND SCHEDULE OF DELIVERABLES;

8135  DUE: 02/28/89  REVISED:           COMPLETED:
      Research Brief:   Modeling bioaccumulation of polar and ionic chemicals by
      fish.
                                        42

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PRINT DATE: 01/30/89
PMS-060
                                                      CLIENT OFFICE
OTS
             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
BUDGET SUB- ACTIVITY:
              ISSUE:
            PPA (L) :

            PPA (S):
                      CODE  TITLE

                      L104  TOXICS
                      D     ECOLOGY: TRANSPORT /FATE /FIELD VALIDATION
                      09    DEVELOPMENT OF VALIDATED EXPOSURE ASSESSMENT METHODOLOGIES

                            EXPOSURE ASSESSMENT
                 RC:  K     ERL ATHNS
            PROJECT:  27    Development of Validated Exposure Assessment Methodologies
    PROJECT OFFICER:  Thomas Barnwell                        PHONE: FTS-250-3210
******************************************
             PLANNED START: 10/01/79     PLANNED END: 12/31/99
******************************************

PROJECT DESCRIPTION:

     GOAL: Develop, parameterize and evaluate multimedia modeling systems and
     continue development and modification of existing models for non-human
     exposures.
     RATIONALE:  OTS wants to upgrade its metals and organics multimedia modeling
     capability for PMN activities and comprehensive risk/benefit analyses on the
     impacts of regulating existing chemicals /species and to account for potential
     toxic effects at the organism and systems levels given various toxics loading
     combinations into surface waters and other environmental compartments.
     APPROACH: Thermodynamic metal species and chemical reaction models will be
     combined with partitioning and bioaccumulation (including plants)  models to
     produce a process-based aquatic distribution package for metal species. Also,
     additional refinements in transport codes (particularly intermedia) and
     transformation kinetics of pollutants will be incorporated into multimedia
     models to produce more reliable exposure assessment packages for organics of
     interest under TSCA and RCRA.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          A standard Fortran-77 computer code of the preliminary 3-D estuary and
     lake sediment transport model was completed. The initial code also was
     documented.  This initial code will be tested at AREAL in the second quarter and
     will be implemented for the Green Bay application.  To aid early testing, the
     University of Florida will maintain a close working relationship to assist
     EPA* s model  application throughout the study period.  During the coming quarter,
     the University of Florida will begin additional development of the sediment
     dispersion model and testing with Lake Okeechobee data. Processing of the
     initial data is continuing.

          AScI tested and debugged the hydrodynamics code delivered last quarter.
     A preliminary test data set for Green Bay was compiled and the code was put on
                                        43

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     a faster computer. A bathymetry data set and segmentation scheme was devised as
     well as a wind field processor and tidal boundary option.

          In the second quarter the preliminary sediment transport code will be
     tested followed by testing and documentation of the hydrodynamics code. A
     preliminary data set for the Green Bay Application of the Sediment Transport
     Model will be developed and additional assistance will be provided to other
     Green Bay reseachers by defining the general hydrodynamics and required linkage
     to the WASP model.

STATUS AND SCHEDULE OF DELIVERABLES;

8047  DUE: 08/31/89  REVISED:           COMPLETED:
      Final Report on Monte Carlo Version of MINTEQ
                                        44

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PRINT DATE: 01/30/89                                  CLIENT OFFICE       OTS
PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS  .
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  L104  TOXICS
              ISSUE:  D     ECOLOGY: TRANSPORT/FATE/FIELD VALIDATION
            PPA (L):  10    TRANSPORT AND FATE PROCESS DETERMINATION

            PPA (S):        TRANSPORT AND FATE
                 RC:  K     ERL ATHNS
            PROJECT:  09    Chemical Process Characterization for Toxics
    PROJECT OFFICER:  Richard G. Zepp                        PHONE: FTS-250-3428
******************************************
             PLANNED START: 10/01/79     PLANNED END: 09/30/99
******************************************

PROJECT DESCRIPTION;

     GOAL: Characterize key chemical processes (direct-indirect photolysis,
     hydrolysis, redox reactions, and sorption/desorption) and expand scientific
     understanding of sediment-water exchange to improve exposure and risk
     assessment models for PMN chemicals.
     RATIONALE: The role of inorganics in pollutant transformation by photolysis and
     the kinetics of redox reactions are inadequately understood for reliable use in
     exposure assessment models. These processes are known to be environmentally
     important; for example, some dyes are rapidly degraded in sediment-water
     systems.
     APPROACH:  Laboratory studies using natural waters, sediments and reference
     materials will be used to accept or reject proposed equations for the kinetics
     and equilibria of transformation and sorption processes.  Rate and equilibrium
     constants to fit the equations will be provided.  Compounds and reaction
     conditions will be selected to permit generalizations about changes in
     molecular structure and environmental composition.  Photochemical studies will
     emphasize the role of naturally occurring inorganic species; redox reactions of
     abiotic systems, relative to biotic systems, will be studied.  Chemical fate
     processes of azo and anthroquinone dyes will receive particular attention.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          A draft paper on the homogeneous hydrolysis rate constants for selected
     chlorinated methanes, ethanes, ethenes and propanes has been written.  This
     paper contains alkaline hydrolysis rate constants and activation parameters for
     15 chlorinated hydrocarbons.  The data will provide a basis for developing a
     structure reactivity relationship for estimation of rate constants for other
     halogenated hydrocarbons.  A draft journal article entitled "Hydrolysis of
     Chlorostilbene Oxide II.   Hydrolysis in Aquifer Samples and in Sediment-Water
     Systems" contains results that provide support for a model that quantitatively
     describes abiotic hydrolysis in heterolytic systems.
                                         45

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          Kinetic studies of the degradation of Solvent Red 1 in anaerobic
     sediment-water systems show that the disappearance of the dye followed
     pseudo-first-order kinetics over two half-lives.  The half-lives in two
     sediments were 94.6 and 67.9 hours.

          Studies progressed on the degradation of diphenyl- and dialkyl-N-
     nitrosoamines in anaerobic sediments. While diphenyl-N-nitrosoamine was
     degraded to diphenyl-amine with a half-life of 11.8 hours, diethyl-, dipropyl-,
     and dibutyl-N-nitrosoamines were stable over a period of 14 days. Sorption
     studies indicate the dialkyl-N-nitrosoamines do not sorb to the sediment and
     that the diphenyl-N-nitrosoamine is only weakly sorbed. These results indicate
     that the diphenyl-N-nitrosoamines will be persistent and highly mobile in
     groundwater environments.

          Studies of the effects of pH on the adsorption of anionic organic
     compounds to sediments have been initiated.  Titration of a well characterized
     sediment using a pH-stat constructed here has shown that, between the ambient pH
     value of 7.8 to approximately pH 5.5, hydrogen ion activity can be controlled by
     the addition of acid (HC1) to within about 0.5 units. Titration of
     pentachlorophenol (POP, pKa equal to 4.8) between pH values of 7.8 and 4.0 in
     EPA 11 sediment (10 g sediment in 200 ml water) shows the concentration of
     pentachlorophenol in the aqueous phase to range from 80Z of total added (at pH
     7.8) to approximately 42 (at pH 4.0). Between pH values of 3 and 4, no
     difference was observed in the partition coefficient. This is highly consistent
     with octanol-water partitioning data for POP in the same pH ranges. Further
     studies controlling the pH at higher values with the addition of base (NaOH)
     are anticipated, along with titration of other compounds having different
     properties.

           Research was continued on the influence of light on the oxidation of
     organic substrates by manganese oxides.  Kinetic studies of the oxidation of
     p-chlorophenol were conducted using monochromatic radiation corresponding to
     the maximum absorption of manganese dioxide (336 nm).  The pH dependence of the
     oxidation rate of p-phenylphenol in manganese oxide suspensions exposed to
     sunlight also was investigated.  Studies of the influence of light on the
     oxidation of anilines by manganese oxides were initiated; the oxidation of
     p-chloroaniline was examined.  Work on the photoredox reactions of copper were
     also continued.  Quantum yields were determined as a function of pH for the
     photoreduction of copper (II) complexed by nitrogen ligands.  Kinetic studies
     were conducted in sunlight for comparison.  Two journal articles were submitted
     for publication during the quarter:  "Hydrogen Peroxide Decay in Waters with
     Suspended Sediments:   Evidence for Biologically Mediated Processes" and
     "Aquatic Humic Substances as Sources and Sinks of Photochemically Produced
     Transient Reactants."

STATUS AND SCHEDULE OF DELIVERABLES:

8137  DUE: 03/30/90  REVISED:            COMPLETED:
      Internal Report - (Research Brief) - Fate of Dyes in the Environment.
                                        46

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PRINT DATE: 01/30/89
PMS-060
     CLIENT OFFICE
OTS
             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  L104  TOXICS
              ISSUE:  D     ECOLOGY: TRANSPORT/FATE/FIELD VALIDATION
            PPA (L):  10    TRANSPORT AND FATE PROCESS DETERMINATION

            PPA (S):        TRANSPORT AND FATE
                 RC:  K     ERL ATHNS
            PROJECT:  37    Microbial Transformation Rate Constants
    PROJECT OFFICER:  William C. Steen                       PHONE: FTS-250-3776
******************************************
             PLANNED START: 10/01/85     PLANNED END: 12/31/99
******************************************

PROJECT DESCRIPTION:

     GOAL:  Develop and apply a system that provides, on a timely basis, second
     order microbial transformation rate constants for suspended organisms in
     aerobic aquatic systems.
     RATIONALE: Under the Toxic Substances Control Act, both new and existing
     chemicals must be evaluated for potential to pose environmental risk from the
     standpoint of toxicity. A major consideration in assessing environmental
     exposure is microbial transformation. Second order rate constants provide a
     means of evaluating potential for microbial transformation at various
     environmental microbial population levels.
     APPROACH: Reproducible second order rate constant measurement techniques will
     be established to relate all chemicals to the same population conditions.
     Second order microbial transformation rate constants will be measured for
     selected chemicals representing each important class of chemicals.
     Relationships between microbial transformation rate and molecular spectroscopic
     properties will be established for base compounds in each chemical class. Rate
     constants for additional compounds of interest will be inferred from their
     molecular spectroscopic properties, which are easily measured.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:
          Second order microbial transformation rate constants were completed for
     seven substituted amides for use as PNN analogies.   They are tabulated below:
                                           k(b)  - L per org.  per hr.
                      Propachlor
                      Proporial
                      N-methylbenzamide
                      Monalide
                      Alachlor
  ,1 X E-9
  ,0 X E-10
  ,0 X E-12
  ,0 X E-13
3.0 X E-13
                                        47

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                       Pronamide                  5.0 X  E-14
                       Niclosamide                2.0 X  E-14

     Measurements  were made using the ERL-Athens protocol  for susjsnxfedt enagsmisns in
     aerobic  systems.

          Compilation  has begun on vibrational spectra  in  different:, meddla* Smr t2»e
     substituted amides.   These data will be used in conjunction wiiflik makmsflalal
     degradation data  both to extend property-reactivity correlations ('KSBCsJ) asaA to
     develop  some  understanding of the importance of solvent  effect^.,

          A new approach  to PRCs is being investigated  that of fen  £&e> paaaimEse of
     utilizing more  of the available spectral information  than is used! alt present, in
     arriving at correlations.   Because more independent data are 3is*?.di,..  G&ursislsctions
     should be more  reliable.

          In  conjunction  with the PRCs of biolysis rate constants aadl sg:©cttaess*copic
     properties mentioned last  month, preliminary work  is  in  progress; tto) ttE3?tt tthe
     feasibility of  direct aqueous injection GC/FT-IR as an altenraaiJve)  teas MilfST-TSi.
     LC/FT-IR is a much more difficult technique to use, but  is  gsnafEaCDl'y $ X< E-H| and
     benzanilide (2.4  X E-12).   These data and the rate constants Eegoaijtifixi! ffirar six
     compounds last  quarter will be compared with spectroscopic  pfjo.p.ear.c-i3es3 fro> assess
     PRCs.

          Four substituted sulfonyl urea herbicides were selected tasr measurement of
     second order  microbial rate constants for PRCs.

STATUS AND SCHEDULE  OF DELIVERABLESt

8136  DUE: 08/31/90  REVISED:           COMPLETED:
      Report:  Microbial  Transformation Rate Constants of  Structurally/
      Man-made Chemicals.
                                          48

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PRINT DATE: 01/30/89                                  CLIENT OFFICE       OTS
PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE.  TITLE

BUDGET SUB-ACTIVITY:  L104  TOXICS
              ISSUE:  D     ECOLOGY: TRANSPORT/FATE/FIELD VALIDATION
            PPA  (L):  11    EVALUATION OF EXPOSURE ASSESSMENT METHODS

            PPA  (S):        MICROCOSM/FIELD
                 RC:  K     ERL ATENS
            PROJECT:  05    Environmental Transformation and Equilibrium Constants
    PROJECT OFFICER:  Heinz Kollig                           PHONE: FTS-250-3770
******************************************
             PLANNED START: 10/01/83     PLANNED END: 12/31/99
******************************************

PROJECT DESCRIPTION;

     GOAL:  Establish and maintain data bases in which data are of known reliability
     for use in  risk assessments, either as "analogs" or as inputs to exposure
     algorithms, and in expert systems for estimating physical, chemical and
     microbial constants. Communicate data to the user community.
     RATIONALE:  Scientifically valid and accurate transformation rate and
     equilibrium constants are required as inputs to mathematical models and other
     decision tools to assess risk associated with toxic and other hazardous
     chemicals.
     APPROACH:   A data base management system will be established that can meet user
     needs. Data will be acquired from the following sources: (1) the literature,
     (2) manufacturers' data submissions to EPA, (3)  computations made by
     technicians, and (A) inhouse laboratory measurements. All data will be screened
     for reliability by applying previously established criteria.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          The computerized Coordinated List of Chemicals (CLC) database, which tells
     who is studying what chemical in ORD, was compiled into a computer executable
     form. The database can now be used on a PC without any additional software.

          A prototype computerized quality evaluation system for the water
     solubility  of pesticides, developed by the Agricultural Research Service, USDA,
     was reviewed.  The system should be useful in evaluating water solubility data
     for any organic chemical.

          Work continued on the development of the fate constant database with
     FOCUS.

STATUS AND SCHEDULE OF DELIVERABLES;

7905  DUE: 03/31/89  REVISED:            COMPLETED:
      Report on problems associated with published environmental fate constants


      5/88 - title change

                                        49

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50

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PRINT DATE: 01/30/89
PMS-060
CLIENT OFFICE
OTS
             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  L104  TOXICS
              ISSUE:  D     ECOLOGY: TRANSPORT/FATE/FIELD VALIDATION
            PPA (L):  11    EVALUATION OF EXPOSURE ASSESSMENT METHODS

            PPA (S):        MICROCOSM/FIELD
                 RC:  K     ERL ATHNS
            PROJECT:  16    Evaluation of Exposure Assessment Methods
    PROJECT OFFICER:  David L. Lewis                         PHONE: FTS-250-3358
******************************************
             PLANNED START: 10/01/79     PLANNED END: 12/31/99
******************************************

PROJECT DESCRIPTION;

     GOAL:  Develop and apply laboratory and field systems for testing transport and
     transformation subroutines, exposure modeling systems, and risk analysis
     systems.
     RATIONALE:  Methodologies for predicting and/or assessing ecological hazard
     have not been adequately tested in complex microcosm and field studies.
     APPROACH:  The use of controlled laboratory ecosystems to evaluate exposure
     modeling systems and risk analysis systems increases the probability of
     attributing a testing mismatch to the appropriate subroutine.  To evaluate
     general applicability, microcosm results are compared with field data.   Field
     and laboratory ecosystems having different physical, chemical, and biological
     makeup are developed and used for testing mathematical methods for determining
     eco-structure, evaluating ecological hypotheses and modeling assumptions used
     for developing generalized predictive models, and testing exposure assessment
     and risk assessment models.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          A completed model of the entire surface water system of the Netherlands
     was received. Analysis of the model revealed a number of features that  will
     require correction. Simulation studies of four test chemicals demonstrated that
     most of the segments are advection dominated and thus of relatively slight
     value in testing process models.  The Dutch Laboratory RIVM is assembling a more
     detailed dataset that is less advection dominated for process model testing.
     Additional chemicals for process  model testing will be identified in the coming
     quarter via analysis of the Dutch WAKWAL monitoring system.

          Inhouse  laboratory experiments to test the hypothesis of a threshold
     critical aqueous blood concentration of a toxicant at which effects on  an
     organism occur are continuing using the neutral hydrophobic test chemical
     1,2,3,4-tetrachlorobenzene (TCB).   These studies are needed to test FGETS and
                                         51

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     for development of effects models and are not being done anywhere else.
     Because of wide ranges in results for plasma and whole body concentrations of
     TCB and plasma content of lipid and moisture, a large amount of effort this
     quarter has been on quality assurance for all these analyses. We are now
     confident the simplified extraction method being used is as efficient and
     consistent as the approved sonication method used by Region IV for extraction
     of organics. Therefore, the variation in the TCB data is real. Plasma lipid and
     moisture determinations have been modified and refined, and we now have
     confidence in those parameters.

          The hard-to-define endpoints with the narcotic chemical, TCB, are still a
     problem.  Bluegill sunfish exposed then sampled when near death or dead (24 to
     48 hrs) have plasma TCB concentrations of from 128 to 775 mg/kg, whereas
     individuals removed at turnover (1 to 2 hrs) have plasma TCB concentrations
     within the same range.  At this point the hypothesis of a lethal threshold in
     the blood for TCB does not seem realistic.  Whole body concentations of TCB,
     however, do show some correlation with death and both parameters are being
     further studied.

          Ongoing and future studies include sequential sampling of blood from a
     living channel catfish during exposure to TCB to determine uptake into the
     blood with time; exposure and sampling of more bluegills to obtain more
     complete datasets; and exposure of guppies to compare whole body concentrations
     at death with those in a study in the literature by van Hoogen and Opperhuizen.
     The project is behind schedule because of very time consuming and specific
     analyses, and the large amount of quality assurance work required. New target
     date is March 1989.

          A report on an Exposure Analysis Modeling System (EXAMS) subroutine for
     predicting microbial transformation rates by biofilms (Gattie, Lewis, Newton)
     has been written and is being internally reviewed.

STATUS AND SCHEDULE OF DELIVERABLES;

8138  DUE:  07/31/89  REVISED:            COMPLETED:
      Report:  EXAMS subroutines for predicting microbial transformation rates of
      aquatic pollutants by attached populations.
                                         52

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PRINT DATE: 01/30/89                                  CLIENT OFFICE       OTS
PMS-060


             FIRST QUARTER STATUS REPORT ON FY*89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNSt OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  L104  TOXICS
              ISSUE:  G     STRUCTURE ACTIVITY RELATIONSHIPS
            PPA  (L):  20    STRUCTURE-ACTIVITY RELATIONSHIPS AND ESTIMATION TECHNIQUES

            PPA  (S):        SAR/EST TECHNIQUES
                 RC:  K     ERL ATHNS
            PROJECT:  10    Predictive Methods for Environmental Exposure Assessments
    PROJECT OFFICER:  Samuel W. Karickhoff                   PHONE: FTS-250-3149
******************************************
             PLANNED START: 10/01/80     PLANNED END: 12/31/99
******************************************

PROJECT DESCRIPTION;

     GOAL: Develop and test concepts for predicting key environmental transport and
     transformation processes for exposure and risk assessments of PMN chemicals.
     RATIONALE: Computational procedures are needed for estimation of photochemical,
     hydrolytic and other transformation rate coefficients used in exposure
     assessments. Such computational approaches minimize the amount of measurement
     required and provide the only independent assessment of measured values.
     APPROACH:  Conceptual relationships and equations relating light absorption and
     rate/equilibrium constants to molecular structure will be developed for direct
     photolytic and hydrolytic transformations and for acidity constants (pKa).
     Process rate and equilibrium constants then will be measured in the
     laboratory using natural components.  Resulting data will be used to evaluate
     and/or modify the concepts and resulting equations.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          The pKa's of esters are being catalogued for continued testing of SPARC,
     the ERL-Athens expert system for predicting chemical reactivity parameters such
     as pKa, hydrolysis rate constants, UV absorption spectra (for photochemical
     degradation rate constants), etc.  Rearrangement of Prolog code for SPARC into
     stand-alone modules has begun, as well as documentation of Prolog code.
     Development of an interface for the spectra database (currently for 200
     compounds) with SPARC is still in progress.

          Three journal articles describing SPARC and its preliminary applications
     are now being cleared at ERL-Athens for publication in one issue of
     Environmental Toxicology and Chemistry.

STATUS AND SCHEDULE OF DELIVERABLES;

8144  DUE:  08/31/90  REVISED:           COMPLETED:
      Report documenting application of expert systems for predicting reactivity
      parameters for PMN chemicals
                                         53

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54

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PRINT DATE: 01/30/89                                  CLIENT OFFICE       OTS
PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  L104  TOXICS
              ISSUE:  G     STRUCTURE ACTIVITY RELATIONSHIPS
            PPA (L)t  20    STRUCTURE-ACTIVITY RELATIONSHIPS AND ESTIMATION TECHNIQUES

            PPA (S):        SAR/EST TECHNIQUES
                 RC:  K     ERL ATHNS
            PROJECT:  15    PRC Relationships and Other Estimation Techniques
    PROJECT OFFICER:  Susan A. Moore                         PHONE: FTS-250-3469
******************************************
             PLANNED START: 05/01/83     PLANNED END: 09/30/99
******************************************

PROJECT DESCRIPTION;

     GOAL:  Expand data bases for establishing property reactivity correlations
     (PRC) and develop quantitative relationships between microbial rate constants
     and molecular descriptors.
     RATIONALE:  There is a need for developing predictive models for fate and
     effects based on structure activity relationships /PRC, because resource
     limitations preclude laboratory characterization of all chemicals of interest.
     APPROACH: Lab studies with natural water samples will be used as a basis for
     assessing formulations for the kinetics of processes describing microbial
     transformation of toxic chemicals. Emphasis will be placed on measurements of
     biomass associated with transformations. A homologous series of compounds will
     be used to examine how changes in compound structure influence the raicrobial
     rate constants. Product analyses will be used to verify common transformation
     mechanisms.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          Changes in river water that occur when it is stored for extended periods
     in the laboratory were investigated.  The significance is, first, that the
     degradative activity of river water may change during storage leading to
     inaccurate conclusions about the degradative activity of the natural setting.
     The goal, therefore, is to identify conditions in which river water can be
     stored in a pristine state.  Second, changes in river water that are induced
     by varying the storage conditions are likely to mimic or approximate
     natural changes due to seasonal and environmental factors, hence identifying
     such factors.  A second river water sample was collected and previous results
     were confirmed and extended.  Storage conditions have not yet been found that
     maintain river water in its original state, but progress has been made.
     Storage of 20 degrees Centigrade river water at 20 degrees Centigrade for 40
     days produced no significant change in total cell concentration, but the
     frequency of occurrence of cell strains changed markedly (based on visual
                                          55

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     inspection of agar plates).  In contrast, storage at -72 degrees Centigrade
     produced a 20-fold decrease in cell concentration after 3 days although the
     frequency of cell strains appeared to remain constant up to 40 days.  Storage
     at 3 and -12 degrees Centigrade produced results that were intermediate between
     those at 20 and -72 degrees Centigrade.  A rnicroplate assay was initiated to
     identify cell strains in river water and better quantitate their frequencies of
     occurrence.  Cell concentration was measured as both CPU on agar plates and MPN
     in liquid medium.  Controls ruled out so called "bottle effects" and effects
     due to the thickness of agar on agar plates.  Rapid freezing and storage in
     liquid nitrogen (approximately -200 degrees C) is being tested.  It may be
     that river water must be reconstituted from stored components in order to
     (re)obtain the original state and allow accurate, reproducible laboratory
     analysis of biodegradation.  The doubling times in rich medium of the fastest
     growing cells that were endogenous to river water were measured in a
     spectrophotometric assay.  Between 10 and 30 degrees Centrigrade, a 10-fold
     increase in temperature produced a 2.2-fold increase in cell growth rate.
     Theoretical analysis of biodegradation by Michaelis-Menten and Monod kinetics
     was continued with a view towards distinguishing between them.  Monod kinetics
     are likely to represent complete degradation of xenobiotics to C02 in contrast
     to the buildup of side products that is typical of Michaelis-Menten kinetics.
     Analysis of physical properties was continued on a second sample of river
     water.  Ultrafiltration was used to separate components by molecular weight,
     and methods for routine organic carbon analysis were initiated.  Degradation
     studies were begun.   Three out of ten samples randomly picked but visually
     distinct clones of microbes from river water were found to degrade 4-chloro-
     aniline within 10 days after inoculation in basal salts medium.

STATUS AND SCHEDULE OF DELIVERABLES;

7916  DUEs 08/31/88  REVISED: 08/31/89  COMPLETED:
      Report: Current use of structure activity relationships for predicting
      biotransformation of chemicals

      5/88- title and due date changed during FY-89 PPA devel.
                                         56

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PRINT DATE: 01/30/89                                  CLIENT OFFICE 	AA_OPTS_
PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  L104  TOXICS
              ISSUE:  I     ECOLOGY: ECTOXICITY AND RISK ASSESSMENT
            PPA  (L):  26    DEVELOP METHODOLOGIES FOR ECOLOGICAL RISK ASSESSMENT

            PPA  (S):        RISK ASSESSMENT DEV.
                 RC:  K     ERL ATHNS
            PROJECT:  13    Predictive Techniques for Ecological Risk
    PROJECT OFFICER:  Ray R. Lassiter                        PHONE: FTS-250-3208
******************************************
             PLANNED START: 10/01/84     PLANNED END: 09/30/90
******************************************

PROJECT DESCRIPTION;

     GOAL:  Develop modeling approaches for assessment of risk from toxic chemicals
     in natural  systems.
     RATIONALE:  Assessing risk from toxic chemicals involves assessments of
     concentration distributions in the environment and of expected effects.
     APPROACH: Exposure analysis models will be used to provide expected aquatic
     environmental concentration distributions. To develop the capability to analyze
     for expected effects, it will be necessary, first, to determine what effects
     are of concern (population, community, second, ecosystem), and the appropriate
     aquatic systems to use to study those effects, and second, to develop the
     appropriate models to represent effects at those levels. Models for effects are
     adapted from existing models or developed on basic principles, as required.
     Finally,  exposure analysis models are linked in a computer implementation with
     effects models via a user-friendly interface to provide the working risk
     analysis modeling system.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          Recruitment was completed for a microbiologist/modeler this quarter.
     Selected candidate is Dr. Rochelle Aurajo from Cornell University,  who will
     report to the project on April 9,  1989.

          Work continued this quarter in design of an experimental GIS interface
     between biological distribution data and simulation model parameter sets.
     Accounts  for all project personnel were  established on the NCC VAX,  and
     authorizations were obtained for use of  VAX ARC/INFO on the CASTOR (VAXB) node.
     The Tektronix 4106 terminal and Tektronix 4105 emulation using PCPLOT+ on the
     PC workstations were set up and tested using VAX sample datasets.  Integration
     of PC ARC/INFO and the NCC VAX version was tested using a sample Digital Line
     Graph (DLG)  provided by the United States Geological Survey (USGS)  on magnetic
     tape for  the Chattanooga area.  A Bailey  ecoregion coverage was designed, and a
                                        57

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 crop  capability  class mapping  from USDA/ARS was located for possible use. These
 coverages will be implemented  in the second quarter of FY89. The availability
 of digital data  for potential  study sites in Georgia, Alabama, and Louisiana
 was evaluated as part of general study design and feasibility exercises.

      Steps for planning the 1989 Ecorisk All Investigators Meeting have been
 taken.  Tentatively the meeting will be held in Athens during the last week of
 February.  Contact persons at  the other Ecorisk laboratories will be contacted
 during the first 2 weeks of January to finalize the necessary arrangements.

      In December ERL-Athens principals met to evaluate the status and direction
 of the Ecorisk Research Program with respect to the integration of existing
 Ecorisk databases and models into Ecorisk Assessment tools that can be used by
 OTS.  Although no definitive decisions were made, several important topics were
 addressed.  These includet (1) Should the research of the Ecorisk program be
 incorporated into a series of  assessment softwares or into a single system like
 GEMS? (2) Is there duplication of effort in the Ecorisk program, for example,
 (a) FGETS and the Erickson/McKim gill model, (b) the ERL-Athens/UGA
 physiological/ecological database and the Dutch biological database, and (c)
 the Biology Branch's planned EXAMS/FGETS/FIS software system and the existing
 CADSWES Sun-based system supported by the Assessment Branch? (3) Should the
 integration of existing Ecorisk databases and models be emphasized during the
 1989 All Investigators's meeting?

     Habitat associations for  approximately 40 species (aquatic and
 terrestrial) selected from the USFWS Endangered and Threatened Wildlife and
 Plants List are still being acquired. Data have come from USFWS publications,
 the Endangered Species Information System (ESIS),  and the Multi-State Fish and
 Wildlife Information System. The BIOTA database will be linked to several data
 layers (land use/land cover, hydrography, political boundaries, etc.) currently
 under development for a CIS-based management tool to determine species-at-risk
 and parameterize exposure and  effects models.

    The cooperative agreement with Montana State University and the University
 of British Columbia is showing good progress.  This work is in support of the
 Ecorisk modeling efforts. Most of the preliminary studies on the respirometer
 itself,  introduction of chemicals and their behavior in the respirometer,
 determination of the most significant tissues  to analyze,  and analysis of
 1,2,3,4-tetrachlorobenzene (TCB) uptake by rainbow trout have been performed
both under static conditions and in the respirometer under different water
velocities or forced swimming  speeds. Uptake of TCB into various tissues
 (plasma,  adipose, pink muscle, white muscle, liver,  brain, heart, kidney,
 liver, gut,  upper gut, gills,  and spleen) has  been determined in fish
 sacrificed times up to 6 hours. The results indicate that the body burden of
the toxicant increased and oxygen uptake increased with swimming speed. Also
tissue levels of the toxicant  showed a constant ratio to the plasma level
 independent of both swimming speed and time of exposure.

     The competitive cooperative agreement on prediction of the effects of
toxicants on natural aquatic populations and biological communities is
proceeding on schedule.  Three preproposals were received and are currently
in the review process.

     Ms.  Sue Wolf presented the paper "Neutral chemical accumulation in aquatic
                                    58

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     plant  shoots" at the Ninth Annual Meeting of the Society of Environmental Toxi-
     cology and Chemistry (SETAC).  Dr. Ray Lassiter and Steven Wooten coauthored
     the paper.  Ms. Wolf was invited by Dr. D. MacKay to present the paper at the
     workshop  "Human exposure to chemicals" held at the Institute for Environmental
     Studies (University of Toronto, Canada). Both presentations were well received.

STATUS AND  SCHEDULE OF DELIVERABLES;

7510  DUEt  08/31/88  REVISED: 08/31/90  COMPLETED:
    '  POPULATION MODEL AND SOFTWARE INCORPORATING LETHAL AND NONLETHAL EFFECTS
      ON FEEDING BEHAVIOR FOR CHEMICALS THAT ACT BY REVERSIBLE MODES OF ACTION

      2/87- due date revised per Russo memo 2/6/87; 5/87 - due
      date  revised to 8/90 during FY-88 PPA planning process as a
      result of reductions in planned resources

7512  DUE:  08/31/88  REVISED: 08/31/90  COMPLETED:
      DOCUMENTATION REPORT ON SPECIFICATIONS FOR INPUT PARAMETERS AND COMPUTER
      CODE  FOR AQUATIC ECOSYSTEM MODELS

      5/87  - due date revised to 8/90 during FY-88 PPA planning
      process as a result of reductions in planned resources

7513  DUE:  08/31/90  REVISED: 08/31/92  COMPLETED:
      COMPUTER CODE FOR FIRST OPERATIONAL VERSION OF AN ECOLOGICAL EFFECTS MODEL
      FOR AQUATIC ECOSYSTEMS

      5/87  - due date revised to 8/92 during FY-88 PPA planning
      process as a result of reductions to planned resources

7514  DUE:  08/31/91  REVISED: 08/31/93  COMPLETED:
      REPORT ON STATISTICAL ANALYSIS OF TESTS OF ECOSYSTEM MODEL


      5/87  - due date revised to 8/93 during FY-88 PPA planning
      process as a result of reductions in planned resources

8146  DUE: 05/31/89  REVISED:           COMPLETED:
      Internal Report:   Products of the Ecorisk Research Program.
                                        59

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60

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PRINT DATE: 01/30/89
PMS-060
CLIENT OFFICE
OTS
             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  L104  TOXICS
              ISSUE:  I     ECOLOGY: ECTOXICITY AND RISK ASSESSMENT
            PPA (L):  26    DEVELOP METHODOLOGIES FOR ECOLOGICAL RISK ASSESSMENT

            PPA (S):        RISK ASSESSMENT DEV.
                 RC:  K     ERL ATHNS
            PROJECT:  28    Risk Assessment Methodologies for Toxic Substances
    PROJECT OFFICER:  Tom Barnwell                           PHONE: FTS-250-3160
******************************************
             PLANNED START: 10/01/85     PLANNED END: 12/31/99
************************ * * ****************

PROJECT DESCRIPTION;

     GOAL:  Develop computerized risk assessment systems that help OPTS analysts
     conduct various tiers of risk assessments efficiently, including methods for
     quantifying uncertainty in risk analyses and procedures for optimal use of
     laboratory data, field studies, and modeling techniques.
     RATIONALE:  Risk assessment requires a wide variety of data and analysis
     techniques to implement the multi-tiered approaches used by OPTS.  Efficient
     software can help OPTS analysts bring together appropriate data and analysis
     techniques in an appropriate structure for each specific risk assessment.
     Present exposure and effects models rarely give the estimates of uncertainty
     that  are required to reduce total uncertainty while minimizing implementation
     costs.
     APPROACH:  Existing software will be reviewed including GEMS, ANNIE, and the
     IIASA-IRIMS system. Related data bases will be assembled and prototype risk
     assessment modeling systems will be developed incorporating all submodels,
     databases and uncertainty analysis techniques. Protocols will be evaluated in
     laboratory and field studies to optimize risk assessment procedures.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


         PC-GEMS distribution and full-fledged use began this quarter by the Office
     of Toxic Substances, in cooperation with the University of Wisconsin
     Continuing Education Program, which began advertising a short course on
     PC-GEMS.

         Dr.  Steve Chapra and Mr. Jim Waterman of the University of Colorado visited
     ERL-Athens to present a seminar on progress to date and to discuss further
     work.  They obtained a copy of the PRZM model to design a new graphics
     interface.  The PRZM graphics interface will be implemented on a DEC MicroVAX
     GPS workstation in order to insure compatibility with ORD hardware.
                                          61

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          The ANNIE-EMIFE integration is proceeding smoothly. A draft report was
     received this quarter and both manual and software were reviewed in depth.
     Comments were received from reviewers at the USGS and from inhouse CSC
     programmers. The software is currently being used inhouse to develop an
     interface for the SARAH model. A short course to teach inhouse staff and other
     interested personnel use of the software is tentatively planned for April.

          A short course on Exposure and Bioaccumulation Models is tentatively
     planned for Athens the week of July 24-28.  The course will be similar
     to the two courses presented in Washington DC and Boulder CO last summer.

          Dr. James Hill has prepared a paper, "Error Analysis of Two Aquatic
     Bioaccumulation Models," that will be submitted to a journal in the second
     quarter.  The paper compares the Thomann-Connolly bioconcentration model to the
     EPA Food and Gill Exchange of Toxicants (F6ETS) model.

STATUS AND SCHEDULE OF DELIVERABLES;

7497  DUE: 09/30/88  REVISED: 11/30/89  COMPLETED:
      Users Manual for Update Stratified Lake Transport Model for Risk Assessment


      to 9/89 as a result of P.O. receiving an OEPER FY-87 2Z Set
      Aside Award for a research project; 6/88 - title change and
      due date to 11/89 due to delay in hiring qualified modeler
      contractor

7499  DUE: 09/30/88  REVISED: 08/31/90  COMPLETED:
       General Bed-Water Exchange Model for Risk Assessment


      2/87- due date revised to 9/89 per Russo memo 2/6/87; 6/88
      due date to 8/90 due to ecorisk research program fund reduc-
      tions

7981  DUE: 08/31/89  REVISED:           COMPLETED:
      Report on Relative Uncertainty of Loading Versus Other Components of Toxic
      Substances Models

      5/88 - title change
                                           62

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PRINT DATE: 01/30/89                                  CLIENT OFFICE       OTS
PMS-060


             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  L104  TOXICS
              ISSUE:  J     SUPPORT
            PPA  (L):  30    TECHNICAL EVALUATION AND ASSESSMENT

            PPA  (S):        TECHNICAL EVALUATION
                 RC:  K     ERL ATHNS
            PROJECT:  31    Technical Evaluation and Assistance
    PROJECT OFFICER:  Lee Mulkey                             PHONE: FTS-250-3160
******************************************
             PLANNED START: 10/01/79     PLANNED END: 12/31/99
******************************************

PROJECT DESCRIPTION;

     GOAL:  Provide technical assistance to OTS and other program offices on complex
     problems relating to environmental exposures, system effects, hazards/risks,
     and benefit-risk assessments for toxic chemical regulation and control.
     RATIONALE:  OTS and other offices (e.g., OW, OPP, OSW and OPPE, Regions)
     engaged in toxic chemical regulations and assessments require technical
     assistance from ORD.  This project will maintain the required inhouse and
     extramural expertise.
     APPROACH:  Athens ERL staff will organize and participate in appropriate
     consultations, workshops, reviews, special projects, etc., in support of OTS
     and other Agency activities, including the review of TSCA documents, position
     papers, strategies, etc., as expertise and resources permit.   Access to "on
     demand" exhouse expertise and assistance for OTS, Regions, States and other
     related office activities also will be provided via maintenance of appropriate
     contracts and liaison with CERI and other Agency support groups.  Support,
     consultation, and assistance to "integrated toxics" projects  also will be
     provided under this project.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:


          A project was begun to characterize the uncertainty in the estimation of
     human inhalation exposure to volatile organic compounds (VOCs) associated with
     domestic water use.  The objectives of this project are to construct a model of
     human inhalation exposure to VOCs from domestic water and to  quantify,  in a
     systematic fashion, the uncertainty associated with the modeling process.

          The project was initiated in November 1988 with the following tasks
     completed to date:

          1.   A literature review to determine what experimentally based data and
              modeling systems have been developed to date.
                                          63

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          2.  A model of human exposure (via inhalation) to VOCs from domestic water
              use (e.g. showers) has been constructed.

          3.  A Monte Carlo shell (software) has been linked to the model to allow
              for multiple executions of the model with randomly selected input
              parameter values.

          4.  A First Order Error Analysis procedure has been designed for use in
              the first model.

          The project is anticipated to conclude in the coming quarter.

          Atmospheric deposition modeling support has been provided for Region V.
     The objective of this project is to perform a 'screening level* study to
     determine the contribution of atmospheric deposition to the total mass of toxic
     pollutants in Lake Michigan.  The project was initiated in September 1989
     with the following tasks completed during the quarter:

          1.  Consultation services were provided to Region V to aid in their
              efforts to write a workplan for constructing a comprehensive toxic
              emission source inventory.

          2.  Contacts were made with members of the EPA Atmospheric Research
              and Exposure Assessment Laboratory (AREAL/Atmospheric Sciences
              Modeling Division) to establish a cooperative effort for completing
              the project.

          3.  In conjunction with AREAL personnel, a draft modeling protocol has
              been generated.

          It is anticipated that the project will continue until the summer of 1989.

STATUS AND SCHEDULE OF DELIVERABLESi

     NO DELIVERABLES AVAILABLE
                                          64

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>RINT DATE:  01/30/89
PMS-060
                                CLIENT OFFICE   OERR
             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE
BUDGET SUB-ACTIVITY:
              ISSUE:
            PPA  (L):
Y105  SUPERFUND
B     EVALUATE TECHNOLOGIES TO MANAGE UNCONTROLLED WASTE SITES
02    Biodegradation Applications to Superfund Site Cleanups
            PPA  (S):        Biodegradation/EPE
                 RC:  K     ERL ATHNS
            PROJECT:  33    Biodegradation Applications to Superfund Site Cleanups
    PROJECT OFFICER:  John E. Rogers                         PHONE: FTS-250-3592
A*****************************************
             PLANNED START: 10/01/88     PLANNED END: 09/01/98
******************************************

PROJECT DESCRIPTION;

     GOAL:  To evaluate naturally occurring and improved microorganisms for the
     degradation of hazardous substances under anaerobic and aerobic conditions.
     RATIONALE:  Increased remedial action activities under the Superfund
     reauthorization will cause a wide range of cleanup technologies to be
     evaluated. Biodegradation in some cases, may be the method of choice over
     chemical and physical remediation. Present knowledge and the availability of
     biotechnologies for remediation must be expanded to meet this need.
     APPROACH:  Pathways and mechanisms for the anaerobic degradation of hazardous
     organic chemicals will be characterized and identified in environmental
     samples. Anaerobic consortia capable of growth on the hazardous compound will
     be enriched from the environment. The key microorganisms in the consortia will
     be isolated and identified. Environmental parameters that either enhance or
     inhibit the activity of key organisms will be identified. Methods for
     moderating or overcoming inhibitory conditions will be developed.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          Pentachlorophenol (PCP) is an environmentally toxic chemical that was
     previously considered recalcitrant to dechlorination under anaerobic
     conditions.  Anaerobic sediments were obtained from a eutrophic lake near
     Athens, GA; the East River in New York City; and a eutrophic lake in the Soviet
     Union near the Black Sea.  PCP was analyzed by extraction with ethanol and
     quantitation with HPLC using a CIS reverse phase column.

          PCP (20 to 30 ppm) is completely removed within 2 days in sediments
     acclimated to dechlorinate 10 ppm 2,4- or 3,4-dichlorophenol.  Chlorinated
     intermediate products are concomitantly observed being tetra, tri, di, and mono
     species with subsequent dechlorination.  By contrast, anaerobic freshwater
     sediments unacclimated to chlorinated phenols require weeks of exposure to
     PCP before significant degradation and removal of PCP (30 ppm) occurs.
                                          65

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     Respiking sediment with PGP results in increased rates of PGP degradation.  All
     degradation rates are apparently first order.   Continued respiking eventually
     results in a slowing of the rate of PGP consumption indicating an inhibitory
     process.

          An abstract, "Dechlorination of Pentachlorophenol in Anaerobic Freshwater
     Sediments" (Bryant, Howard and Rogers), was submitted for the 1989 ASM Meeting
     in New Orleans, LA, in May.

STATUS AND SCHEDULE OF DELIVERABLES;

8238  DUE: 10/31/89  REVISED:           COMPLETED:
      Report:  Potential uses of isolated natural organisms to enhance
      bioremediation of mixed hazardous wastes.
                                         66

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'PRINT DATE:  01/30/89
 PMS-060
CLIENT OFFICE
OERR
              FIRST  QUARTER  STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
                Office  of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
 ******************************************
                       CODE  TITLE

 BUDGET  SUB-ACTIVITY:   Y105  SUPERFUND
               ISSUE:   F     PROVIDE TECHNICAL SUPPORT TO ENFORCEMENT, PROGRAM & REGIONS
             PPA (L):   22    Enforcement and Other Technical Support/EPE

             PPA (S):        Technical Support
                  RC:   K     ERL ATHNS
             PROJECT:   04    Enforcement and Other Technical Support/EPE
     PROJECT  OFFICER:   Donald L. Brockway                     PHONE: FTS-250-3422
 ******************************************
              PLANNED START: 03/30/87     PLANNED END: 12/30/99
 ******************************************

 PROJECT DESCRIPTION;

     GOAL: Provide  tech. support, expert advice, & new methods to Regions assessing
     exposure/risk  at  CERCLA sites; emphasize hazard ranking process & subsequent
     RIFS analysis, particularly ecological risk.
     RATIONALE:  Exp. assess, and fate multispectral ID techniques for chemicals,
     databases  for  environ, properties, & process transform, descriptions are
     completed  or under dervelopment. Application to CERCLA ranking & assessment
     procedures  has been limited. Work with Reg. 4/ATSDR will permit immediate use
     of methods,  identify knowledge gaps, and focus study of exposure, health, and
     environmental  assessments.
     APPROACH: ERL-Athens,  the Regions (via Reg. 4), & ATSDR will identify, develop
     and demonstrate improved exposure and risk assessments. Improved ecological
     factors  for the hazard ranking system (HRS) will be developed. Case studies
     will include application of existing ranking methods (HRS), multimedia analysis
     models,  and ecorisk procedures. Results will be used in evaluating existing
     CERCLA protocols, in transferring technology, and in evaluating need for more
     research on pollutant  fate and exposure/risk assessment.. Occurrence of new
     hazardous  source  chemicals will be reported to OERR.

 PROJECT STATUS AND ACCOMPLISHMENTS TO DATE:


          ERL-Athens conducted for OERR/HQ a technical review of the
     document,  "Ecological  Assessments of Hazardous Waste Sites."  This
     document was prepared  to be a resource to field Superfund personnel involved in
     ecological  assessments, and includes components on assesment approaches,
     endpoints,  toxicity testing, biomarkers, and field surveys.  As a resource, the
     document is  thorough but its utility will be limited because of little "how to"
     guidance in  choosing among, for example, the large population of toxicity
     tests.  Review of the  document also was obtained from the University of Georgia
     Institute of Ecology, which is being funded under the Superfund Ecorisk
     Technology  Support Center at ERL-Athens.
                                          67

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          The pilot study of results for Tentatively Identified Compounds (TICs)
     from Superfund Contract Laboratories (CLPs) continues.  All of the sample runs
     from Superfund CLPs have been processed, and data analysis is proceeding.
     Thirty-five retained extracts and CLP report packages corresponding to many of
     these runs also have been obtained through the help of the Superfund Sample
     Management Center.  Instrumental runs on the extracts, aimed at identifying
     those TICs that are of interest, have begun.

STATUS AND SCHEDULE OF DELIVERABLES;

7966  DUE: 02/28/89  REVISED:           COMPLETED: 12/31/88
      Report on recommendations for improving the ecological factors ot the hazard
      ranking system

      6/88 - title change
                                         68

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PRINT DATE: 01/30/89
PMS-060
CLIENT OFFICE
OWPE
             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  Y105  SUPERFUND
              ISSUE:  F     PROVIDE TECHNICAL SUPPORT TO ENFORCEMENT, PROGRAM & REGIONS
            PPA (L):  22    Enforcement and Other Technical Support/EPE

            PPA (S):        Technical Support
                 RC:  K     ERL ATHNS
            PROJECT:  23    Anaerobic Biotreatraent Development/SF
    PROJECT OFFICER:  John E. Rogers                         PHONE: FTS-250-3592
******************************************
             PLANNED START: 09/30/87     PLANNED END: 12/31/99
******************************************

PROJECT DESCRIPTION:

     GOAL:  Characterize and identify basic biological processes that lead to the
     anaerobic degradation or detoxification of hazardous wastes in contaminated
     sites.
     RATIONALE: A reliable approach is needed for selecting and using biotreatment
     processes in the remediation of contaminated hazardous waste sites.
     APPROACH:  Pathways and mechanisms for the anaerobic degradation of hazardous
     organic chemicals will be characterized and identified in environmental
     samples.  Physical and chemical processes affecting the rates also will be
     characterized.  Computer subroutines will be developed to model the processes
     and effects.   The subroutines then will be incorporated into larger computer
     models for estimating the efficacy of proposed bioremediation processes.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          Information required to adequately evaluate biological treatment
     proposals targeted for the remediation of hazardous waste sites was defined at
     a workshop sponsored by the Office of Solid Waste at the Environmental Research
     Laboratory -  Athens on December 13 - 15.  Products of the workshop were: (1)
     a summary of  the types of information that would be needed to evaluate the
     efficiency of a treatment scenario,  (2)  a list of methods or protocols that
     could be used for developing the appropriate data, and (3)  a list of EPA
     scientists who could provide assistance to those responsible for evaluating
     treatment scenarios. Presentations were made by EPA scientists, Dr. J.E.
     Rogers,  ERL-Athens,  Dr.  J.A. Glaser, RREL-Cincinnati, and Dr.  P.H.  Pritchard,
     ERL-Gulf Breeze, and by three university and two industry scientistss. EPA
     attendees came from OSW,  OWPE, ORD,  and Regions 4, 7, 8,  and 10.

          Georgia  pond sediment enrichments on p-Cresol (pCr)  were  examined
     under methanogenic,  denitrifying,  acetogenic (BESA)  and sulfidogenic
     conditions.   Loss of pCr (1 mM)  took from three to four weeks  in all four
                                         69

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     systems.  Rate of parent substrate loss in methanogenic cultures was slower
     than that in denitrifying and acetogenic cultures.  Under sulfate reducing
     conditions pCr was metabolized coincident with 3.3 raM net loss of sulfate, 78Z
     of the theoretical amount.  Percent conversion of substrate carbon to gas in
     methanogenic cultures was 67.7% with 53.9Z as CHA.  Cumulative raraol of CH4
     generated was 89Z of the theoretical.  Inhibition of CH4 formation in BESA
     cultures was incomplete.  Acetate was detected only in BESA inhibited cultures.
     Under denitrifying conditions, stoichiometric conversion to gaseous end
     products was observed (92.8% of N03 was found as N2 and 5.4% as N20).  A
     transient intermediate,  p-hydroxybenzoate was detected, suggesting that pCr
     metabolism under NO/-3/- reducing conditions proceeds through p-hydroxybenzoate
     and is mediated by a pCr methylhydroxylase as previously shown.  These
     results indicate that pCr is susceptible to degradation under a wide variety of
     anaerobic conditions.  An abstract, "Anaerobic biodegradation of p-Cresol
     under four reducing conditions" (Rivera, Bossert, Haggbloin, Rogers, and Young)
     was submitted for the 1989 ASM Annual Meeting to be held in New Orleans in May.

STATUS AND SCHEDULE OF DELIVERABLES!

     NO DELIVERABLES AVAILABLE
                                          70

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•PRINT DATE: 01/30/89
PMS-060
CLIENT OFFICE
OERR
             FIRST QUARTER STATUS REPORT ON FY'89 PROJECT DESCRIPTIONS
               Office of Environmental Processes and Effects Research
                         ERL ATHNS: OCTOBER - DECEMBER 1988
******************************************
                      CODE  TITLE

BUDGET SUB-ACTIVITY:  Y105  SUPERFUND
              ISSUE:  F     PROVIDE TECHNICAL SUPPORT TO ENFORCEMENT, PROGRAM & REGIONS
            PPA  (L):  22    Enforcement and Other Technical Support/EPE

            PPA  (S):        Technical Support
                 RC:  K     ERL ATHNS
            PROJECT:  29    Center for Exposure Assessment Modeling
    PROJECT OFFICER:  Robert Ambrose                         PHONE: FTS-250-3160
******************************************
             PLANNED START: 08/01/87     PLANNED END: 12/30/99
******************************************

PROJECT DESCRIPTION:

     GOAL:  Provide regional technical support, expert advice, specialized training,
     and new methods to conduct exposure assessment modeling for CERCLA sites. To
     meet ecological impact needs, risk assessment assistance will be provided.
     Emphasis is on site-specific modeling support and review.
     RATIONALE: Exposure assessment modeling technology for human and ecological
     risk is under development, or completed. Application and transfer of this
     technology has been limited because the required highly specialized expertise
     has not been available or accessible to the Regions and their consultants.
     Providing a dedicated, operational center for modeling technology will promote
     existing programs and provide feedback to ongoing research programs.
     APPROACH:  The Agency's Center for Expsoure Assessment Modeling (CEAM) will work
     with the regions and ATSDR to identify support needs, conduct site-specific
     assessments, and provide continued technical support.  Modeling software, users
     manuals, data bases, and procedural handbooks will be developed, distributed,
     maintained and supported.  Case studies will be conducted with emphasis on
     multi-media assessments and associated uncertainties.  Results will be used for
     technology transfer and as a basis for additional research.

PROJECT STATUS AND ACCOMPLISHMENTS TO DATE;


          The ORD Center for Exposure Assessment Modeling (CEAM) staff gave several
     presentations on Superfund projects this quarter. Mr. Ambrose presented
     "Modeling the Loading, Exposure,and Acute Toxicity of Copper and Zinc in the
     Upper Clark Fork River"(SETAC);Dr. James Martin presented "Modeling of Confined
     Disposal Facilities" (SETAC); Dr. Zia Hosseinipour presented "Ground Water
     Management at Waste Impoundment Sites" (International Conference on Advances in
     Groundwater Hydrology); Mr. Ambrose presented "Fate and Transport Modeling of
     Wood Preserving Contaminants in Surface Water" (Forum on Remediation of Wood
     Preserving Sites); Mr. Ambrose presented a review of CEAM Superfund activities
     at the Superfund Technology Support Project's fall General Meeting; and
                                          71

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 Dr.  Martin participated  in  expert panel  review of  the Hyde Park/Lake Ontario
 dioxin modeling  study.

 Clark Fork River Superfund  Site—Developed model network and input data to
 simulate hydrodynamics and  mass transport of metals in Clark Fork River between
 the  Berkeley  Pit and Deer Lodge. Prepared and submitted an abstract that
 discusses  the hydraulic  model and surface water transport model applications of
 the  Clark  Fork River Project to the June 27-30, 1989 Missoula MT,
 Symposium  on  Headwaters  Hydrology.

 Modeling of Confined Disposal Facilities—Completed review and modeling report
 of the proposed  Waukegan Harbor Confined Disposal  Facility and submitted to
 Region 5.  Attended meeting  November 3 in Grosse lie MI to present
 results to state agency  and plan for Saginaw Bay studies. Completed literature
 review of  sorption of PCBs  on sand filters. Initiated work on revising methods
 for  computing dike transport.

 Great Lakes Modeling Activities—Completed review  of revised report on modeling
 of dioxin  in  Lake Ontario as part of Region II study. Reviewed first draft of
 dioxin study  report by the  Large Lakes Research Station and participated in
 teleconference with other members of expert panel  of Hyde Park/Lake Ontario
 study. Review incldued verifying model selected computations and predictions.

 EcoRisk Support--FCHAIN  and FGETS models.  Reviewed relevant literature on
 ecological  risk  assessment.

 Technical Assistance—Provided Robert Hayzen, NJDEP, assistance investigating
 the problem of on-site human exposure to hexavalent chromium at about 100
 hazardous waste  sites in New Jersey. Provided Bonnie Eleder, Region V Remedial
 Project Manager, with a  review of the Sheboygan Harbor and River, Wisconsin
 Remedial Investigation/Feasibility Study Project.  Introduced Laura Mazanti,
 Jeff Stone, Ron  Landy, and  Judy Sophianapoulos EPA Region IV, to PRZM. Gave
 demonstration of how to  develop input sequence and what parameters are
 required. Provided Dave  Hill, Region IV, advice on use of MINTEQ in predicting
 lead solubility  and speciation at battery cracking superfund sites--Kassouf
Kimberling and Flowood.   Provided Dave Hill, Region IV, general information and
 advice on soil cleanup levels targeted for the CSX train wreck site.  Provided
John Prince, Region II Super RPM for Myers Property Site, NJ, information on
potential dioxin risks to humans from contaminated soil and drinking water.
Provided Stephen Cipot,  Region II,  information on the RUSTIC model and training
 course for possible use  at  two superfund dry cleaning sites.

Model Distribution—The CEAM Electronic Bulletin Board System (BBS)  continued
 to be well used. Seventy new users registered this quarter,  making a total of
389 users.  477 calls were placed to the BBS,  and 14 datasets uploaded from
users for debugging by CEAM staff.   The following exposure models were
distributed:

          Model       Diskette       BBS       Tape
          WASP4          27           16         0
          HSPF9          23            03
          MINTEQA1       57            31
          EXAMSII        20            32
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               PRZM           16           11         3
               LC50            5            60
               SARAH           9            10
               FGETS          13            10

     Model Support—Continued development, testing, and support of WASP,
     PRODEF/MINTEQ, and Multimedia models.  Began quality assurance/quality control
     checks and tests of WASP model and support programs and documentation for
     release of version 4.14 for VAX and PC system implementation, execution, and
     documentation.  Continued migration of CEAM model distribution and registered
     user data base from VAX to PC environment.

STATUS AND SCHEDULE OF DELIVERABLES;

8167  DUE: 08/31/89  REVISED:     COMPLETED:
      Training Courses for Regional Superfund Staff on Exposure Assessment
      Modeling

8168  DUE: 07/31/89  REVISED:     COMPLETED:
      Research Brief on Exposure and EcoRisk Assessments Performed by Center for
      Exposure Assessment Modeling

8169  DUE: 08/31/90  REVISED:     COMPLETED:
      Training Courses for Regional Superfund Staff on Exposure Assessment
      Modeling

8170  DUE: 07/31/90  REVISED:     COMPLETED:
      Research Brief on Exposure and EcoRisk Assessments Performed by Center for
      Exposure Assessment Modeling
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