United States
Environmental Protection
Agency
Office of
Reseach and
Development
Energy,,
Minerals and Industry
Washington, D.C. 20460
EPA-600/7-77-004
January 1977
            FISCAL YEAR 1976/HEALTH AND
            ENVIRONMENTAL EFFECTS
            RESEARCH PROGRAM ABSTRACTS
            Interagency
            Energy-Environment
            Research and Development
            Program Report

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                       RESEARCH REPORTING SERIES
Research reports of the Office of Research and Development, U.S.
Environmental Protection Agency, have been grouped into seven series.
These seven broad categories were established to facilitate further
development and application of environmental technology.  Elimination
of traditional grouping was consciously planned to foster technology
transfer and a maximum interface in related fields.  The seven series
are:

     1.  Environmental Health Effects Research
     2.  Environmental Protection Technology
     3.  Ecological Research
     4.  Environmental Monitoring
     5.  Socioeconomic Environmental Studies
     6.  Scientific and Technical Assessment Reports (STAR)
     7.  Interagency  Energy-Environment Research and Development

This report has been  assigned to the INTERAGENCY ENERGY-ENVIRONMENT
RESEARCH AND DEVELOPMENT  series.  Reports  in this  series result from
the effort funded under the 17-agency Federal Energy/Environment
Research and Development  Program.   These studies relate  to EPA's
mission to protect  the public health and welfare from  adverse  effects
of pollutants  associated  with energy systems.   The goal  of  the Program
is  to  assure the rapid development  of domestic  energy  supplies in  an
environmentally—compatible manner  by providing the necessary
environmental  data  and control  technology.  Investigations  include
analyses of  the  transport of  energy-related pollutants and  their health
and  ecological effects; assessments of, and development  of,  control
technologies for energy systems; and integrated assessments  of a wide
range  of energy-related environmental issues.
 This document is available to the public through the National  Technical
 Information Service, Springfield, Virginia  22161.

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                                       EPA 600/7-77-004
                                       January 1977
FISCAL YEAR 1976
HEALTH AND ENVIRONMENTAL EFFECTS
RESEARCH PROGRAM ABSTRACTS
Interagency
Energy/Environment
Research and Development
Program Report
               Project Officer

              Richard M. Laska
   Office of Energy, Minerals and Industry
     Office of Research and Development
           Washington, D.C. 20460
OFFICE OF ENERGY, MINERALS AND INDUSTRY
  OFFICE OF RESEARCH AND DEVELOPMENT
 U.S. ENVIRONMENTAL PROTECTION AGENCY
        WASHINGTON, D.C. 20460

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                                DISCLAIMER
   This report has been reviewed by the Office of Research and Development,
U.S. Environmental Protection Agency,  and approved for publication.  Mention
of trade names or commercial products does not constitute endorsement or rec-
ommendation for use.
                                    ii

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                               FOREWORD
      This volume is one of two works. Together they contain project-level
descriptions of nearly all  of the $100-million in research and development
funded by the EPA-coordinated Interagency Energy/Environment R&D Program
in fiscal year 1976.  This is the second year in which this office has  prepared
such a program listing.  To  make this year' s effort more useful,  we have
coded the edges of the pages with marks .  The wide marks indicate the Inter-
agency Research category in which the project falls.

      The project-level descriptions  in this volume describe the  health and
environmental effects research funded by the FY 1976  Interagency Energy/
Environment R&D Program coordinated by the  Office of Energy, Minerals and
Industry. Each project is assigned to one  of five research, development,
and demonstration categories:
      •  Pollutant  characterization, measurement,  and monitoring
      •  Environmental transport processes
      «  Health effects
      •  Ecological effects

      e  Integrated assessment

Within each R&D category,  program abstracts are grouped by  agency.  A table
of contents has been provided at the beginning of each R&D category.

      Project descriptions are culled from "Notice of Research Project" forms
prepared by the appropriate  laboratories and agencies using the Smithsonian
Science Information Exchange (SSIE)  format.  The enclosed tables reflect the
FY 1976 Interagency Program budget.  Table 1 delineates total funding by
R&D category and  agency.   Tables 2-6 illustrate the funding for  each  of the
five research categories.  Each table (2-6) shows funding by  energy source
for each performing agency.  Tables  7 and  8 give the funding  summary by
energy cycle component (extraction,  processing,  transportation and conver-
sion,  and utilization).

      In a companion volume,  similar information on environmental control
technology addresses:
      •  Energy resource extraction
      «  Physical and chemical coal  cleaning

      •  Flue gas cleaning
      •  Direct combustion

      •  Synthetic fuels
                                  111

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• Nuclear
• Thermal
• Improved efficiency
• Advanced systems
                            iv

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INDEX

        CHARACTERIZATION
        MEASUREMENT AND
        MONITORING
        ENVIRONMENTAL
        TRANSPORT
        PROCESSES
        HEALTH
        EFFECTS
        ECOLOGICAL
        EFFECTS
        INTEGRATED
        ASSESSMENT
 V

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                               ABSTRACT


    This report includes SSIE  (Smithsonian Science Information Exchange)
abstracts to the FY 1976 Interagency Energy/Environment Research, Develop-
ment and Demonstration Program being coordinated and managed by EPA' s
Office of Energy,  Minerals and Industry.  The abstracts are organized by
the five major health and environmental research categories:

                 • Pollutant Characterization,
                   Measurement and Monitoring

                 • Environmental Transport and Fate

                 • Health Effects

                 • Ecological Effects

                 • Integrated Assessment

    This volume includes research being accomplished by EPA and its labora-
tories as well as  a number of the participating agencies of the Federal Government,
                                   vi

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                        TABLE OF CONTENTS

                                                              Page

Foreword                                                       iii

Index                                                          v

Abstract                                                        vi


I. HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH
           FUNDING

Table No.                                                     Page

    1       Health and Environmental Effects Research             ix
           Funding by Research Category

    2       Characterization, Measurement and                   x
           Monitoring Funding

    3       Environmental Transport Processes Funding            xiii

    4       Health Effects Funding                               xv

    5       Ecological Effects Funding                           xvii

    6       Integrated Assessment Funding                        xxi

    7       Percent Funds Allocation by Energy Cycle             xxii
           Component and Research Category

    8       EPA and Pass-Through Funding Summary by            xxiii
           Energy Cycle Component and Research
           Category
                               vii

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                        TABLE OF CONTENTS
                            (Continued)
II.  HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH


Section                                                       Page

   A       Characterization, Measurement, and
           Monitoring

   B       Environmental Transport Processes

   C       Health Effects

   D       Ecological Effects

   E       Integrated Assessment
                                viii

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                                                                     Table  1
                                                      OFFICE OF ENERGY. MINERALS,  AND INDUSTRY
                                                        OFFICE OF RESEARCH AND DEVELOPMENT
                                                         ENVIRONMENTAL PROTECTION AGENCY

                                                   FY 76 INTERAGEHCY ENERGY/Er.'IRONMENT PROGRAM
                                                               FUNDING SUMMARY ($K)
  RESEARCH CATEGORY
                                     EPA
                                                                               PERFORMING AGENCY
                                               TVA     ERDA   NOAA    USDA
                                                                              HUD   COMMERCE   NIEHS   DOl-FSHS   FPC   NIOSH   NASA   USGS
                                                                                                                 PASS
                                                                                                                 THRU
                                                                                                          NBS    TOTAL
                                                                                                                           GRAND
                                                                                                                           TOTAL
Characterization, Measurement,
and Monitoring                       3,118.2

Environmental Transport Processes    3,130

Health Effects

Ecological Effects
Integrated Assessment

       iTOTAL
             280     669   1,050

             566     652     375

                   2,600

             812    1,050   1,478   1,413

 2,020       238     220   	     396    £2

17,835.4   1.896    5,191   2,903.  1,809    92
5,447.2

4,150
                                                  55_

                                                  55
2,993

  179    2,293
                                                                                               3,172     2,293
                   50

                   50
  341    696    989   1,041    5.066    8.184.2

                               1,593    4,743

1,889                          7,482   12,929.2

                               7,225   11,375

	    	    	   	    1.051    3.071

2,230    696    989   1,041   22,417   40,302.4

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                                                                         Table  2
                                                       FT 7J DITEIlAGCNCr WEKCT/ENVIRONMENt FXOCMM
                                                             nWODW SUMMARY JT ENERCT SOURCE
                                                  FOR CHARACTERiZATiOM.  MEASUREMENT. AMP HOHITORIMC ($r.)
                                                                                          mrocr
irforwlng
.geney

 E?A
      Labor a t q^^»nd^JPirpgraii

La* V«ga*-EnvlronB«QC*l Monitoring
mod Support Laboratory

1.  En«rg7 ralmtaH wattum rational
    air aumitarlnf
2.  Enargy rtlfttad vatar ..on 1 tar In t

3.  Eaargy ralacad groundiratcr
    •oni toeing and t«chnlqrj«a
                                     S«b-0b5acel«     Suo-                   oil/   Oil                C«o-           Va»ta    Cot.*»«r-   Hultl-
                                     Statqaene Coda  CatBgorr*  Total  Coal   Caa   Shala   Huclear    thetuml  Solar  aa-Fual  yatloo    fv*l_
4.  tnerjy ralatad orarhaad Krai-
    torlng and tttcholqu«a dcv«lop—
    Mnc
5.  Energy r*Latad radiological
    pollutant Monitoring and tach*
                                                   78AJP+
                                                   78AIB
                                                   78ABH
                                                   78ABI
                                                       2A
                                                       2A
                                                                  U
875
125
                                                                             *00
                                                                             200
       775
       100
                                                                                    130  100
                                                                                    140
                              100
                               25
                                                                                                150
                                                                                                 50
                                                                                                          10
niquea development
monitoring qv " ' :r
for Boaitorint; '
pollutant! an^ ^ :
.TOTAL LAS VL-.W -'.

aaeuranca
L >ehalquea
• :• related

78AJJ
78A1R
78ABK

ZA
2D
a, K

to
(3
175 125 50
(1,950) (1,290) (130) (325)
90
85

(185)
Cincinnati - EnvlrattzMHital Honl**
torlng and Support: laboratory

1.  Energy related vacer BOnltorlng
    tachalflnea deYftlopttenC
Z.  Energy related vater aonltoriag
    quality easuranee aupport
       IOTA]. CtHCIMU.II
                                                   7SA&M

                                                   78ASQ
2C

2L
 125     50

 125    100

(250)  (ISO)
                    25

                    25

                   (SO)
                                                                                                                                                      50
                                                                                                                                                     (50)
  Reaearch Triangle Fark - Envlron-
  •ental Monitoring and Support
  Laboratory

  !•  Energy related air aonltorlng
      quality aaaurance aapport
  2.  Energy related air pollutant
      •eaauraenta and inetnmentatlon
      developoent
         TOTAL KTF/EHSL

  Research Triangle Park - Industrial
  Environmental Reaearch Laboratory

  1.  Dealgn and fabrication of a
      aetvice aMeanenc aaxpling
      •yetern
         TOTAl
  Athene * Environmental Raaearch
  Laboratory

  1.  Energy related low level trace
      contaminant identification..
      •eaaareaent and analytia of
      •olid vaete and effluent vater
         TOTAL ATH£HS
                                                     78ABP
                                                     78AJBL
                                                                    2D
                                                     78A>K
                                                                               250    220
                                                                                                   30
                                                                               420    320   50     50
                                                                              (670)  (5*0) (50)   (80)
                                                                               16}
                                                                                                                                                       165
                                                                                                                                                      (165)
                   TOTAL CHARACTERIZATION, HEASUHEMDJT.
                    AND
  115     35  40
 (115)   (35)(«0)

3,150  2,015 240
                                                                                                  455
                                                                                                            25
                                                                                                           (25)

                                                                                                           110
                                         U
                                        (15)
                                                                                                                                             215
   •  225 from region VIII

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                                                                                          Table  2
                                                                        FY 76 INTERACENCY ENERGY/ENVIRONMENT PROGRAM
                                                                              FUNDING SUMMARY BY ENERGY SOURCE
                                                                     FOR CHARACTERIZATION, MEASUREMENT. AND MOHITORIHC ($K>
Performing
  Agency

  HIOSU
  ERDA
   SASA
   nscs
   XBS
         Laboratory and Program

1.  Develop instrumentation and devices {or
    the.measurement of hazardous agents In
    the occupational environment associated
    with energy usage (75; J. Lynch)

        TOTAL SIOSH

1.  Development of advanced air monitoring
    instrumentation and methods
    (75; H. R. Wasson)
2.  Development of aqueous effluent instru-
    mentation and methods for energy-related
    sources (75; U. R. Wasson)

3.  Energy-related health Instrumentation
    and methods development (75; H. R. Wasson}
        TOTAL ERDA

1.  Technical support for western energy
    related environmental assessment/overhead
    monitoring method development
    (75; E. L. Tllton)

2,  Energy related remote sensing Instru-
    mentation development
    (75; S. P. Mufler, Jr.)
       ' TOTAL NASA

1.  Water monitoring  field instrumentation
    development  (75;  P. Greeson)

2.  Energy related surface water monitoring/
    western region (75; F. A. Kllpatrick}

3.  Energy related groundwater monitoring/
    western region study  (75; F. A. Kilpatrick)

4.  Energy related surface and grounduater
    monitoring studies/western region
    (75; F. A. Kilpatrick)
5.  Energy related surface grounduater
    monitoring studies/eastern region
    (75; F. A. Kilpatrlck)

        TOTAL USGS

1.  Energy related water pollutant analyses
    Instrumentation (75; J. R. McNesby)

2.  Energy related water pollutant standard
    reference materials (75; J. R. McNesby)
3.  Energy related air pollutant standard
    reference materials (75; J. R. McNesby)

4.  Radiological pollutant quality assurance
    (75; J. R. McSesby)

        TOTAL KBS


Sub-Objective
Statement Code
78BDE

78BCG
78BCU
78BCJ

7BBEL
78BEV

78BBX
78BBZ
) 78BBY
78BBWa
78BBWb

78BCK
78BCM
78BCL
78BCN



Sub-
Cateeorv*
2B

2B
20
2B

2A
2B

2C
2A
2A
2A
2A

2C.2B
2D
2D.2B
2D

(Continued)

Total Coal
341 191
(341) (191)
315 315
213
141 141
(669) (456)
550 450
146 146
(696) (596)
,380
175
. 739
••125
180 J
129 55
(989) (739)
250 100
300 175
440 325
51
(1.041) (600)

ENERGY SOURCE
Oil
Oil/Gas Shale Nuclear
50
(50)

70 73

(70) (73)
50 50

(50) (50)


250

20
(250)
50 50
100
100
51
(50) (250) (51)
                                                                                                                         thermal   Solar
                                                                                                                                                                Multi-
                                                                                                                                                                Fuel
                                                                                                                                                                     100
                                                                                                                                                                    (100)
                                                                                                                                         70
                                                                                                                                         (70)
                                                                                                                                          SO

                                                                                                                                          25

                                                                                                                                          15



                                                                                                                                         (90)

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                                                                                         Table  2

                                                                       FY 76 INTERAGENCY ENERGY/ENVIRONMENT PROGRAM
                                                                             FUNDING SUMMARY BY ENERGY SOURCE
                                                                  KIR CHARACTERIZATION. MEASUREMENT, AND MONITORING ($K)

                                                                                        (Continued)
Performing
  Agency
                      Laboratory acd  Program
Sub-Objective
Statement Code
                                                                                         Total
               ENERGY SOURCE

                  Oil
                 Shale  Nuclear
  Geo-
thermal  Solar
 Waste-   Censer-   Multi
.os-Fuel   vatlon    Fuel
 HOAA       1.  Atmospheric and meteorological studios
                of pollutants from energy production
                (75; R. F. Pueschal)                           78iEG          2B
            2.  Meteorological Interpretation and pre-
                diction of air quality In the western
                United States related to energy
                activities (75; R. Machta)                     78BEK          2A
            3.  LIDAR techniques for measuring partlc-
                ulate pollutants from energy production
                and their transport and dispersion
                processes (75;. V.  E. Derr)                     78BEB          2A
            4.  Standardized and intercallbrated tech-
                niques for marine  monitoring
                (75;  R.  J. Farland)                            78BEA          2D
            5.  Ocean oil spill concentration and
                trajectory forecast                            78BDTC          2A
                (75;  C.  S. Barriontos)
            6.  Underway water sampling system
                (75;  M.  E. Rlniin  Sach)                        78BDX          2A

                   TOTAL NOAA

 TVA        1.  Isolation and Identification of water-
                borne pollutants associated  with the
                power Industry (steam electric power
                generation)  (75; C. H. Holley)                 78BDH          2A

            2*   Development  and evaluation of an
                integrated approach to the optimiza-
                tion  of  nuclear power plant  radio-
                logical  surveillance programs
                (75;  J.  A. Oppold)                              78BDI           2B

            3.   Synoptic monitoring of SOj effects on
               vegetation (75;  T.  J.  Montgomery)               78BDK           2D

                   TOTAL  TVA

                   TOTAL  PASS  THRU

                   TOTAL  CHARACTERIZATION, MEASUREMENT
                    AMD MONITORING
                               100




                               205



                               200


                                75

                               150
                                        100
         205
200
          75

         ISO
                               320               320
                            (1,050)     (300)     (750)
                                50       50
                               130

                               100       100
                              (280)     (150)

                             5.066     3,032      920
                         130



                        (130)

                  623    231
                             8,184.2  5,047    1,160    1,078    441
                                    160


                                    175
                           100


                           100      183.2
  Sub-Categories:  2A  MULTI-MEDIA HONITO.UNG AND MONITORING TECHNIQUES DEVELOPMENT
                  2B  AIR INSTRUMENTATIOM
                  2C  WATER INSTRUMENTATION
                  2D  QUALITY ASSURANCE

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                                                                                 Table  3
                                                                      orncx or mater. HIKOULS, AND
                                                                        omot or USEAXCH tm DCVCLOPHEHT
                                                                         tKTntownrrju. nuoncriOM AGBKT

                                                                    n 7* nnauccHCT nrencT/EHvuomnrt mocuM
                                                                         TWTOISC SUHUKT ET EHCXCT SOUICt
                                                                    TO» BrmoKHprfAt mmsroirr noccssts  (»r.)
                                                                                                           IUMI  SOURCX
rarfomlna.
  Aa*ncT
                  rrolaet Paaerlpclon

SM       ATftDIS LAI

          >.   Tata of aracKtc pollocaata U Craali


                 TOTAL UHEHS
                                                              ln      Su»-
                                                    StaCaaant Cod*   Cacalorr  Tot a.
                                                                                                             Oil
                                                                                                               Coo-
                                                                                                     Huel««t   th«cm«l   Sol.r
                                                                                    ttt     IU     135

                                                                                    (»5O)   (213)   (131)
                                                                                                             (90)
             nr ui
             1.
                 •tudlu oC
                 la til*
                                                                                   l.iSJ   1,U4     in

                                                                                  a,M3) (1.114)   (371)
             UK UI
             1.
                 pollvtanta  in ground i
                                                                                     350     Ml

                                                                                    (350)    (2»»)
                                                                                                           }J

                                                                                                          (JZ)
             ODHAU.IS UI
             1*  DvcvcmlM triovformmcloa
                 phy«lc*l «ad eh«aie*l p«rtutb«tlofi
                 •ttd toxlclcr of  crnda oil Co tttth-
                 mt«r oTg«ii«»«  in vrecie l*kM«

             2.  tetorBiao trnuporc paehvcr*. traaafir
                 tatci «nd Cat* of poilnconca Kid
                 tf«tr«dacion produeca of eruda oil la
                 a0U and aetlv*  layar of pasaafroac
                 tctrala-
             3.  DatarmiiM Bacbaniana of eraoafermattoaa,
                 dagradatloa. lata and atfacc at etuda
                 all In atr«a» acoa^atan,  (120C)          CKE-ottA
                                                                                                 100
             4,  bcanalon of Hnlcl-layaf.  two-
                 llMnaional (horizontal) aodal of
                 circulation co aeeapc  a haacad dlaehar
                 aa a pollocanc

             5.  Datatminatlon of paralatanca and dim-
                 aaraloo of ehlotina ttom OB-*nor«
                 cooling diaehartaa

                     TOTU. COtTAJJ.H
                                                                                   50      IS     U

                                                                                 (4001    (50)    (350)
              COlf UXDC tA»
                  Daear.in. th.
                  and dlaaltatlon  in aarina and m
                  Mtara ~o cb. .<£a«t. o., «arlna u*L
                  aacuarlna or»«ni»«a. •** lonftarai
                  acoaraca. la»act. o< .«" »••««"•
                                                   of
•loeldaa darlrtd
ahora po~c plane
•odala of tha (at
thanal ud btocl
contiollad (laid
rM eoaacai ana o&&^
. Don lop acoayattm
and aifacta of
a dinhatgaa ranglot
onic uiaaatlagaa n»
tiallaa.
                      TOTAL GOUT Iff OX
                                                                                      230

                                                                                     (ISO)
                                                                                            M

                                                                                           (M)
                                                                                                        13

                                                                                                        (S3)
UKO» rill

1.  Katntanaaca of air anallty —nltorlnt
    aatvork  to eootinua to datina long
    t.rT •••«"" «•" I-"™"1""   OT-*"»

        TOTAL UCICM  Tilt

        TOTAL PA
                                                                                      11]     1M

                                                                                      «1J)   UM)

                                                                                    3.150   1.S81
                                                                                                      939
                                                                                                             IS

                                                                                                            (M)

                                                                                                            167
                                                                                              xiii

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                                                                                      Table  3
                                                                            wnot or EHDun. HIXZUIJ, AHD imxm«r
                                                                              OFFICE or  tzsuneu ua DEVELCWEHT
                                                                                txtivxuanu. mntctva ACEHCT

                                                                          n it  mrrucDKT raact/ravraosmaiT FIOCUM
                                                                              rtdffilM SIMUAT BY WERCT SOOKCS
                                                                           104 EHVItOKtfMTJU. TUjUlSPOItT PROCESSES (JO
                                                                                                                  EHgiCT SOOTCT
	                                                Sub-Object ft*      fab-                                Oil               C-JW-             ««.«ar-«   COM**—   Hulct-
 AtrocT                  ItoUcc Dwripcioo               Statataanc CoJ«   Caoaorr   Toc«X    Ccai   Oil/C^a   Shall   HucU«c   th«nt*l   Solar     Fu«l     yatlon    fual

  WA        I,   CvAluatiM flt »od*l* tor pr*dUeiJ.|
                 cwltoi»cie«l lap««e of S»MOV* r«l*«««a
                 fTiw nucU*r pov*.; plane*
                 (75t J.  A. Dppollo)                          78.UH           3.V        50                               50

             1.   D*«10(.tac of 3lM.lt.tloa Hod*I* of
                 Tharvail  filupcrcloe of fluid i
                 Ifl icrflauu aUa«l r»*«rvotr*
                 (75; V.  ft. Hlctkoiu)
                 eo*L-flr«d
                 (75; T.  ttoa

             4.  rorMacion r«e«a of Ijwriuic* of acid*
                 fro* «erip-«lii«« ud ci'saAporcacloa la
                 v««cv«y> (75| II. t. KlcholM)

             S*  Dor«n4a«clMi of pcftfttaeo And «buad«]c»
                 of p«scc aad qu«aclutl«» •ttalflc4aco
                 ia iftlactod tcrlp •!«•• poolj
                 (75| y.  t. Ulcbolu)
                                                                                                                                                                         (U)
                 la  »ti4V-«urf»ca kTccie ecoaysEwi
                 (75; C. Uhic«>                               78Ki            tt         71               n

             2.   Fan tmtl •{feet* of polluCMti la
                 (•rr*«CciAl •ccwyBCc.ia la /aar comarm
                 tr** uui HoJ; J. If. ToM«.tod)                         IHI-4.UC         X        375                                                                               173

                    TOTU. WU                                                        (JJJ)                                                                             075)

                    TOTAL FAS3-TURB                                                  1.59J     «0x      573               M                                             4W

                    TOTAL OWTWt*l£i!-fj.l. TtAJDmn PROCESiES                          4,743   I.U1    1.3U     167      133                                             4tM
                  3»  AiHosrimRic ntxtssis
                  3>  FRCSIIUATER pnocEssRa
                  3C  KAJtlue/ESTUAilHS PROCESS!!
                  3D  TEUCSniU. PCOCESSE!
                  ix  9MUTIOM or emaoaama. TUHSKKT
                                                                                             xiv

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                                                                                        Table 4
                                                                             OFFICE OF  ENERGY, MINERALS, AND  INDUSTRY
                                                                              OFFICE OF RESEARCH AND DEVELOPMENT
                                                                                ENVIRONMENTAL PROrzCTIOH AGENCY

                                                                            FY 76  INTERACENCY ENERGY/ENVIRONMENT PROGRAM
                                                                                FUNDING SUMMARY BY ENERGY SOURCE
                                                                                   FOR HEALTH EFFECTS ($K)
Performing
 Agency
                     Project Description
Cincinnati   CINCINNATI HEALTH EFFECTS RESEARCH
             LABORATORY

             1.  Water exposure and their effects:
                 heavy metals and toxic organic chemicals

             2.  Multi-route exposures and their effects

                     TOTAL CINCINNATI
                                                                                                                        ENERGY  SOURCE
Sub-Objective      Sub-
Statement CoJe   Category
  EHE-625F

  EHE-625F
 4B

4C.4E
                                                                                          Total
                                                                                                      Coal
                                                                              SAO         840

                                                                              510.2        510.2

                                                                           (1,350.2)    (1,350.2)
                                             Oil               Ceo-
                                  011/Gas   Shale   Huclear   thermal
                                                                                                                                                  Waste-as   Conser-   Multi-
                                                                                                                                          Solar    Fuel      vatloo    Fuel
Research
Triangle
Park
RESEARCH TRIANGLE PARK - HEALTH EFFECTS
RESEARCH LABORATORY

1.  Characterize human exposure to pollu-
    tants emitted In ambient air as a
    result of coal conversion and utiliza-
    tion                                         EHE-625F

2.  Under controlled experimental condi-
    tions assess human exposure - effects
    relationships                                EHE-625F

3.  Develop and apply cytologlcal, bio-
    chemical, and physiological indicators
    of blodjtnage resulting from exposure co
    pollutants associated with energy
    development                                  EHE-625F

4.  Identify the hazards of chronic, lou
    level exposure to 85K. and -*ll as it
    relates to nuclear energy production         EI1E-625F

        TOTAL RTP

        TOTAL EPA
                                                                              4A.4B
                                                                              4D.4E
                                                                               4D
                                                                                         1,300       1,300
                                                                                           777
                                                                                         1,620
                                                                                                       777
                                                                                                     1,265
                                                                                           400

                                                                                        (4.097)      (3,342)

                                                                                         5,447.2     4,692.2
                                                                                                                           125
                                                                       400

                                                              (125)     (400)

                                                              125      400
                                                                                                                                                                          230
                                                                                            (230)

                                                                                            230

-------
                                                                                    Table  4
                                                                          orrxcE or ENERGY. HIHKMU. AND  TNMJSTM
                                                                            orrtct or RESEARCH ANI> DKVELOPHEWT
                                                                                           mOTECTlON ACE4CY
                                                                        rt 7* nrrawcCTCT wract/nwuoNMOiT PROGRAM
                                                                            FUNDING SUmWY BT ENERGY SOURCE
                                                                              FOR HgALTTi Ej|T ECTJfc  (SO
                                                                                                                    FJtncr  SOURCE
                                                         Sob-01.J»et [..      3ub-                                      Oil                Cv>-
                                                         St«t«»«cit Cod.   C.t.ioi-T      Tat«l     Co«l     Otl/C««    ni«H   »uel««c    th«nmt
             OCCUPATIONAL HEALTH DTeCTS RZSXAJtCB
             ASSOCIATED WITH EHEACT TECHNOLOGIES AND
                 TOTAL R103H
                                                                            48
                                                                           AC.*
                                                                                       1,889

                                                                                       U«BB9)
                                      700

                                     <700)
                                                                                                         l.U*
                           ffieti oa etll* *od
                            r«Multiflc frxni po
                  Cnm «i«cg7  t«chnolo»i«»
                  (75; L. C. lUrt)

             2.   Doc* «ff«et  r«l«tioa»hlp Cor
                  *[f*cta of tonic «|«flci In *a
                  t*ehtwloglM  (?5i R. U
             3.  D«v«lop «nd  t«*t «rf«li »oJ concept*-
                 for »ictr«pcl*tiofl of cellular and
                 aniaal d*tm  to um uolng  toxic  •|[«nt«
                 (row rnaTU  tcchnaloglK*
                 (75; 0. C. Ho«U

             4.  D«e«rmln« doa* «f£«cta of  «xiw*ur«  Co
                 •otagtaie *«  ucoclace
              S.   A»
                                       .  r»c«,  end  to»i-
                            i**cciftt*J  vith  «a«c|y  tictr
                  w)logi«i  (75;  L.  C. fUrt)

              6.   Develop phy«Jolo§icjl Indicacot*  of
                  4*Mg* tro« toxic ig*nts
                  (75:  F. D«3«rt««)

              7.   Hechentinw of  Incorporation,  »*t*bo-
                  lls«.,d«pcsltlc)n ,  and  turnover of
                  enttyj- evicted Kjirrdoiw BALerltis
                  (75;  R. L. Dlxott)

                      TOTAL KtKRS
                                                                                                                    950
77ECQ
                            306

                         (2.W3)
             1.  Idoattfy th«
                                   potent
                 logicxllr dotriErantil « gents 1JJ
                 procca* »tr«aa« product* end by-
                 yroducte and «£fly«nt« Ceo* «*jor
                 Coeell fuel CTtractlen end coovex-
                 • 1cm technoloKles (75; C. E. St*?M
             2.  &«T«lo(> cjwlosicul and blochBrie«l
                 Indlc&tor* to esciajce coxlcit^ front
                 oil end e6ei excrar.tion, coirvacmioa,
                 end utillsetlon (75; C. D. Dude)

             3.  Determine effects *nd OTEAQ dteCri-
                 button of H«tardous trace ncele wvl
                 polycyellc hydrocarbone eauocieted

                 conversion, mtJ utilixetioa
                 (75; H. Schulun)

             4.  Avoes* ch« htiBcdt of crsce cod heevr
                 ewcels of rvoo-oue leer eaergr c*ch-

                 tsoiy^e pwtt«rris ind ter«.Co^cne
                 effect* on *&>**+ Li an enbrro* »*
                 Indlcecort <75; D. R. Perker)

                     TOTAL EKDA

                     TOTAL PASS-TREO

                     TOTAL HEALTH EFT^CTS
                                                                            U           («}
              U         l.MI
              <>           316
                           SS6

                         (2.«00)
                                                                                                                 I.9C4
                                                                                      11.869.2   6,028.2
                                                                                                       !,1M    4,897

                                                                                                       I,*19    4,847
4A  n>EHTinCAT10N OF HAIAWXXJS  AGEKTS
«B  MSI A*T> DAHACC itrorcAToas
*C  HFTABCLISH OF HAZARDOUS  MTCTTS
4D  EVALUATIOH OF HAZARDS  TO MAM
41  DAKACK,  REPAIR. AMJ RECOVMT FSOCESSBS
4X  SIMUTIOH OF HEALTH EFFECTS
                                                                                               xvi

-------
                                                                Table  5
                                                      OFFICE 0V ENK1CT,  MINERALS. AJIO  IKWJ3TCT
                                                        OFTICC Of RESEARCH AND DEVELOPHEVT
                                                         DI7UONMEHTAL PKOTECTION ACEXCT

                                                    FT 7* OmtACDtCT CNnCT/EXVIIlOHHElfT  FXOC1LAM
                                                                 SUHMAJtT BT INHRGT  SOUKCX
                                                             FOR ECOLOGICAL EFFECTS (?K)
tarforwlaa.
 „.«§«"
  IT*
NAUACAMSm

1.  Dvrvlopncat of H»d«l« for
    of ?ollntant Impact l «id Oil 3!ul« Prc»««»
 1.  tet*ndutloa of Loar*t«ca £ffcctc on
     V«*c« K«at in the Surface v«cir«  of
     Clw Cr«AC LcitM fl««ln on Ao  cad CjaumiUy I

          IOTAL niurra
                                                              Dtt-*J5A         5»      1,179      9*2
                                                                        (1.263)  (1,037)
                                                                                                     (183)
        vtn

     Bw»»i«»™-"t:  -*  •  rr^pfifetasl.Ta  itfar-
     •atlon protil"  for Major fr««hvce««
     •qoacle *avironn«nc»  that could ba
     affacCed by  «n«rgr d*vmi&f**iat.  Thin
     will ba &»« througb  «  mmtfc^r of r*-
           i »v*clflc bioloflcal icudlLw.
                                                             EiS-t2St.         K        UO       K
     Davalopa*aC of  «»*»i«
     Cvdura  ac  g*oth«n§»l  •!(••.   Idamti-
                       ba
                         *C cf
                         f Ciom «o*r^7  tmmaur
                          Hwaa vtll  iacluda
                  v«tar aad air
                                 l»7*cta
                                 cm dav«l-
                                 U«* BM.
 4.  AM*Ma*ftt of  tha  Ivpact* of axpact-
    •iMl «f  tb« uranium  loduatry.

         TOTAL UCICH  Till

         TOTAL ETA
                                                              U/3I/3C     U9      123
                                                                 31        133
                                                                                                                        (*0)
                                                                                       (»10)    (113)                     (133)

                                                                                      4,130    1,173     1,1)3     103     193
                                                                               xvii

-------
                                                                                              Table  5
                                                                                              -tXCKT. XIHMALS. AHtJ  IHDUSTUt
                                                                                      orriot or UIEAICH  AND umioiHort
                                                                                        EH? IKOlfHEMTAI. PIOTEcnoN /CZHCT

                                                                                  IT  76 ISTTUCDICT  EOTICT/CnriBMHWT HOCKAM
                                                                                               SUHHUT >t EHCXCT sound
                                                                                           FO« ECOLOGICAL Erncta  («>
PerformlAB.                                                Sub-ObjactlT*      Sub-                                  Oil                 Ceo-              Vaett    Conaar-  Knltl-
                         Prolaee DeacrHtlon              State-eat  Coda    Category   Total     Coal     OU/Ca»    ihala   Unclear   thermal   iol«c    ea-fuel   rettoo.   Fuel—
                                                                                                                                                                           230
 IIOA       1.   lifoste of Oil Spill,  on Tundra and         UZ-4I3A       3A/3»        33                31
                Than Panda

            2.   (ffacta of Cometruetlcn Operation*          HH-42JA         31         60                60
                of Alaaka PipellB* o«  Aquatic
                Babltato

            J.   Ufeeta of Trece  Hetale on Crop and         79KC            3A        230                                                               —
                toreat Icoeyeto*  (73 f  0, Ballaatiae)

            «.   lloloflcal Indleaa of  Pollutant Ct>         BHE-«I3A         it        200                                                                —                20*
                fecta en FTOooveCar Ecoeyeteme
                (73j C. C. Covtaott Primary  laveetiiator)

            >.   Lout-Term Effect, of Brdrourbona           tBX-«25A       31/3C       230                                                                —                15°
                na Selected Kcoeyatana and Aeaociatad


            i.   Sumya on Oil Extraction and Trana-       7  vi_.  Ortnlinf  of UjO

            3.   Syoarsietlc Action of  Temnaratura                            5C         43                                                                __               (133)
                U1U, other Foliutmta  Herlna Spesleg
                (Vetteorata lad Invertebrsta) Karioa
                Sendee

            4.   Kalationahia  Between Toale Fractiona                         SC         44                44
                of Crude Oil  and  Petroleu* Prodncta
                and Tumor  Formation In nerlnm Speciea
                (Dr. Larry Bart)

                     •UBS (HEW)  TOTAL                     77BC7                     O'9)               (44)                                              _


 OSDA       1.   Aeeaee Qnellcy of  Vater In Strip-
FOtBST          Killed AreEa ea it  Relaeea te axfaitat
SaaVlCX         for Airueclc Orienieiv  and Wildlife
                Speeiaa Aeeoclated with thaaa Water
                todlee
                 SUbtli>inf of Hlna Spolla and Identi-
                 fy Technelofiee that will Zahence
                 Hater quality for Aeaoeieted Aquatic
                 Ufa

             3.  Aaaaaa Effecte of Hlntne-ftealtcd                         9A/5B/3C
                 Tranapottation Syetama La Water, Alrv
                 Soil. Plant. Aalaml and Aeatheclr.
                 Kaeoureaa

             4.  Daralop Operational Technical Informa-
                 tion Syotm for Reclamation of Undo
                 Affected by nioln, (73i a. L. lerron)

                      FOKUT 3E171C1 TOTAL                                             (313)     (383)
                                                                                      XV 111

-------
                                                                                Table  5
                                                                     OTF1CI Of ERERCr, HIHTRALS, AND  IMWSTTTI
                                                                       OFFICE OF RTSEAROl AJfD DCVEtOPKEHT
                                                                          BITtROHWDfTAL rROTtCTIOK ACEHCT
                                                                   FT  7»  1HTESACD4CT CTmCT/EHVIKOHHEHT PRflCKAH
                                                                                SUWWJIT  Bt EHERCT SOURCE
                                                                            FOB ECOLOCICA^ EyFECT3  <$*)

                                                                                   (CoatliHiwl)
                                                                                                                XH71UJT  SOURCE
  AKTOCT               Project D«BCI

DDABTK2BT   I.  Straarlt* R««ult>  <
                                                                                                                                                                 Coo«*r-  MuiCt-
                                                                                                                                                                          Fuai
    or
 DITEUOK-
 risH AKO
VTXD LITE
 S1EV1CE
                 tff Ev&iuAC* Cb* PhygiaJUieical, Taxi-
                 colojlc*! tnd Ecolojlcal UfvcC* of
                 Oil PrlBtfiJLr OQ Duck*,
                 (75 j i. r, scick«i>

                 Dwcrlb« Ef(«cti»* Cuid«llou tfld
                 Hatbodoiocy for tfe* D*v*l6^»»ae(
                 Sytithwl*, Att«l7«t* «od lDt*rpr*t«-
                 tlo« of Cae^lax t^aloatc-J.  ud Bto-
                 ]jt>slc«d Information RtlatlT* CO
                 Itejor Co*»t*l £u«r*tMM.
                 (73 t K. T.lt)

                 Fr»per« RcporCa o« Tbr»« Co*sC*l
                 R*8loo« Subject to Eoarsj Dwslopacot.
                 P1&C* E*ph»«l« on 7*_Lu* at  K«KKETU«
                 •uch u rich, UiltUlf* Knd  EcolofficU
                 Froct«>«i Subject to Hart-Induced Co-
                  (73; B. I *it>

                  IdnClfj «nd r^
                                               of
                                                d,  Covt-
                 torytnj tad Ch«r«ctBrtilQ9
                 Habit.  Sp«cl«l £apbuU b«tnn Plftcad
                 on ftaqulxa*tat« Cor  Food, Co^^c,  Breed-
                 ing mad Othar Critical  facctm.
                 (73; JU B. Stwuc.  Jr.)
                 Colorado  and  Dpp«r
                                                              Wf-ilSt        3C         300
                                                                               !A        700      700
                                                                :-6JSt          5»         uo
                 i«ct*4 by
                 lotb I*eC
                                  s Flov  K4Chodolo^M  Co
                                   KJ>
                                            Ar*«9 Af-
                                                                              »        2»
                  tor th» AcbXrttl
                  Spttdc* 1& Arv«*
                  Ca«rC7 Dc»«lop«e
                   DIP   XEKT 0»
                                                                                       (2,293)    (700)       (930)

                                                                               sc         wo                «oo
                                  <75t H-  3,
                          of P*tn?l«t»-««l*t«d Accivltlcn
                  OB  Horch«n3  P«5«C  Sound  mad StTiit ««
                  JWB d. Fuc..   (75 [  D. 1.  UoU*)
                  F*rfon «  Co«partBoo/Afl*lr«lB  of an
                  Ezlxclnc ferio*  £coerac«» Uad«r Scr«e*
                  of  *a ActlT* OH Fi«bi vlth «  51*11*=
                  Ccevyttca  la tn  Dndl*c«b*4 Arm*.
                  (75;  D.  Anc*lortcJ
                                                                                          320
                                                                                5C        155
                                                                                                             320
                                                                                5C
                                                                                          103
                   for I
                   tad H
                   (73l
                           I.  Vy«tt>
                        KUA TOTAL

                        TOTAL PASS TSSD
                        TOTAL ECOLOCICAL ZTFECtJ*
                                                                                       a.*78>            (1,478)
                                                                                        7t213   2.W3      2.S22
                                                                                       11.375   *,77>      *,207
          ECOLOGICAL  EFTTCTS             _
               5A  TFMFSTHtAL  FCO^TSTTM F-FFRCTS
               JB  FRESHWATER ECOSTSTEM  rFTTCTS
               5C  KARIKI/C3TUWIHK ECOSTSTW ITFlCTS
               31  SIMUTIOH OF ECOLOGICAL EFTtCTS

-------
                                                                                  Table  5
                                                                        76 INTERAGENCY ENERGY/ENVIRONMENT PROGRAM
                                                                          FUNDING SUMMARY BY ENERGY SOURCE
                                                                              FOR ECOLOGICAL EFFECTS ($K)
                                                                                       Continued
 Performing
 _Agency
                        Project  Description
                                                           Sub-Objective
                                                           Statement Coda
                                                               78BEI
AGRICULTURAL   1.  Develop Reclamation Plan Before
  RESEARCH         Mining Operation Begins.
  SERVICE          (75; H. L. Barrows)

               2.  Determine Effect of Strip-Mining
                   and Reclamation Processes on the
                   Quality and Quantity of Hater
                   Leaving the Area.

               3.  Determine Effect of Strip-Mine
                   Reclamation Practices on the
                   Nutritional Quality of Foraget or
                   Other Crops Crown on Reclaimed area.

                    AGRICULTURAL RESEARCH SERVICE TOTAL
COOPERATIVE    1.  Assess and Model Effects of Previ-          EHE-125A
   STATE           ous Mining Methods, Spoil Cliarac-
  RESLARCH         terlatics and Reclamation of.
  SERVICE          Surface and Crounduater.

               2.  Conduct Experiments on Plants of Fast       EHE-62iA
                   Growing Trees to Assess Grovrth Support
                   Capabilities of Specific Sites in Re-
                   lation to Water Quality and Spoil
                   Clu racterliitlcs.

               3.  Expand Existing "Resources Inventory,       EHE-C25A
                   Information Management and Monitoring
                   Systens" for Collection, Annihilation
                   and Analyses of Natural Resources and
                   Pollution Data Related to Coal
                   Extraction.   (75;  S.  Aldrich)

               4.  Evaluate Species and  Seed Sources for       EHE-625A
                   Revegetation of  Energy Resource Ex-
                   traction Areas with Native Plants.

               5.   Detcralne  Soil Characteristics Develop-      EHE-625A
                   ing on Spoils  of Varying Agia Relating
                   to  Koot Growth and Biological Produc-
                   tivity.
                   COOPERATIVE STATE RESEARCH SERVICE          EIIE-625A
                                                 TOTAL

                   USDA  TOTAL                                  EHE-S25.-.
                                   EHEBCX SOURCE

                                      Oil
                           Oil/Caa   Shale   Nuclear
Solar
         Ui»te
        «8-Fu«l
Conser-
vation
Hultl-
Fuel
                                                                                5A
  SB        330     330




  3A          8



            330     330


  SB        100     100




  5A         75      75





3A/5B        SO      SO






  5A        100     100



  5A        ISO     ISO



            475     475


         (1,413) (1.413)

-------
                                                                                           Table 6
                                                                               FT 76 ICTERACEtfCY ENERGY/ENVIRONMENT PROGRAM
                                                                                    FUNDING SUMMARY BY  ENERGY SOURCE
                                                                                     FOR INTEGRATED ASSESSMENT  (SK)
DEFT. Of
OMtZICE
             OFFICE AMD PROCRAM

OEHI (04
53
131
(238)
220
(220)
92
(92)
50
(50)
55
(55)
655
1,740



-------
                                                     Table 7

                                     OFFICE OF ENERGY, MINERALS, AND INDUSTRY
                                        OFFICE OF RESEARCH AND DEVELOPMENT
                                         ENVIRONMENTAL PROTECTION AGENCY

                                   FY 76 INTERAGENCY ENERGY/ENVIRONMENT PROGRAM
                                    FUNDING SUMMARY BY ENERGY CYCLE COMPONENT
                                                              Energy Cycle Component
         Sub-Category

Characterization, Measurement
and Monitoring

Environmental Transport Processes

Health Effects

Ecological Effects

Integrated Assessment
Extraction
9.5
2.3
7.7
9.1
3.8
32.7
Processing
Transportation, Conversion
3.3
3.9
11.5
10.5
2.2
31.4
Utilization
7.5
5.6
12.9
8.6
1.6
36.2
Total
20.3
11. a
32.1
28.2
7.6
100.0
 Data expressed as percentages of the total Interagency
 Energy/Environment FY 1976 funding for the Processes
 and Effects Program ($39,564,200)

-------
                                                                     Table  8

                                                         OFFICE OF ENERGY, MINERALS, AND INDUSTRY
                                                            OFFICE OF RESEARCH AND DEVELOPMENT
                                                             ENVIRONMENTAL PROTECTION AGENCY

                                                       FY 76 INTERAGENCY ENERGY/ENVIRONMENT PROGRAM
                                                        FUNDING SUMMARY BY ENERGY CYCLE COMPONENT
                                                                     Energy Cycle Component
          Sab-Category

Characterization, Measurement
and Monitoring

Environmental Transport Processes

Health Effects

Ecological Effects

Integrated Assessment
Extraction
EPA
1,455
535
1,310
1,316
1,292
37908
Pass
Thru
2,374.5
381
1,808.2
2,341.2
242
7,146.9
IAG
Program
3,829.5
916
3.118.2
3,657.2
1,534
13,054.9
Processing,
Transportation. Conversion
Pass IAG
EPA Thru Program
508
825
1,945
1,525
364
5,167
828.5
762
2,688
2,713.7
525
7,517.2
1,336.5
1,587
4,633
4,238.7
889
12,684.2
Utilization
EPA
i
1,127.2
1,790
2,208
1,251
364
6,740.2
Pass
Thru
1.891
450
2,970
2,228.1
284
7,823.1
IAG
Program
3,018.2
2,240
5,178
3,479.1
648
14,563.3
EPA
3,090.2
3,150
5.463
4,092
2,020
17,815.2
Total
Pass
Thru
5,094
1,593
7,466.2
7,283
1,051
22,487.2

IAG
Program
8,184.2
4,743
12,929.2
11,375
3,071
40,302.4

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A.  CHARACTERIZATION, MEASUREMENT AND MONITORING

-------
                       TABLE OF CONTENTS





             Characterization, Measurement and Monitoring






Agency                                               Page




 EPA                                                 1-43




 ERDA                                                44-52




 NASA                                                53-54




 NBS                                                 55-66




 NOAA                                                67-82




 TVA                                                 83-85




 USGS                                                86-112

-------
                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                               Form Approved
                                                                             OMB No.  113-R0081
                                                                    PROJECT NO. (Do not us* thlg space)
                                                                    ssie
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                           CAA
                     IN  SUPPORT OF B1ERGY RELATED  MONITORING ACTIVITIES IN THE WESTERN U.S.
OWE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
                     E.  P. Parry
                     M.  Cher
                     G.  Colovos
                     L.  S. Shepard
NAME AND ADDRESS OF APPLICANT INSTITUTION
Rockwell  International  Air Monitoring Center
2421A West Hillcrest  Drive
Itewbyry  Park. CA  91320	
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Currant Plans and/or Progress (200 words or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work In progress are exchanged with government and private agencies sup-
porting research and are forwarded to Investigators who request such Information. Your summary is to ba used for these purposes.


     Task I - Laboratory and  sita  inspection, evaluation  and  reporting.
     Task II - Par-romance surveys  in which  blind samples and calibration equipment
        C      are shipped to the  laboratories to evaluate sample analysis  and
                calibration performance.
     Task III -  Technical assistance to the  various laboratories.
IDENTIFY PROFESSIONAL SCHOOL INVOLV
denfa/. ere.)
                                            SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                          DATE

                                                          August 20, 1975
                                         FOR OFFICE USE ONLY
    SUPPORT METHOD fCdect onej
           STAPP (Intramural)
                                                   PROJECT OFFICER
                                                      Machta
                                                   RESPONSIBLE ORGANIZATION
 FUNDS OBLIGATED

 lf 260,2-9 f
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                                                             STARTING DATE
^ESTIMATED COMPLETION
 DATE
 EPA Form 5740-1 (7-72)    REPLACES PHS FORM 168 AND SI-SIE 76* WHICH MAY NOT BE USED.

-------
                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                                Form Approved
                                                                              OMB No.  1S8-K0081
                                                                    PROJECT NO. (Do not tat (Me ,ptcf)

                                                                    SSIE
                                                                      PA
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          CBB
TITLE OF PROJECT	
   Provide QC Samples  to the Quality Assurance Branch
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.


   Not awarded  to date.
NAME AND ADDRESS OF APPLICANT INSTITUTION
   Not awarded  to date.
SUMMARY OF PROPOSED WORK -  (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 word, or la.a. Omit confidential data).
   En the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencl.a sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for theae purpoeea.


   1.    Objective

         Produce reference quality control samples In such areas as (1) trace
         metals. (2)  turbidity,  (3) nitrates  and fluorides, and  (4)  organic
         compounds.

   2.    Approach;

         The contractor shall produce quality control samples  according to exact
         Instructions submitted  by the  Quality Assurance  Branch, EHSL-C1nc1nnat1.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
                                             SIGNATURE OF PRINCIPAL INVESTIGATOR
                            Not awarded to date
                                                                                   DATE
                                                                                     9-15-76
                                          FOR OFFICE USE ONLY
    SUPPORT METHOD (Chech onej
    «06NCY STAFF (Intramural)
    RESEARCH GRANT
                               TASK NO.

                               1
                                                    PROJECT OFFICER
                                            L.  Berg     X7326
                                                    RESPONSIBLE ORGANIZATION
                                                     EMSL-C1nc1nnat1
FUNDS OBLIGATED
  $63,000
76
STARTING DATE
 9/29/76
ESTIMATED COMPLETION
°*TE  9/29/79
 EPA Form 5760-1 (7-72)    REPLACES PH5 FORM 166 AND SI-SIE76A WHICH MAY NOT BE USED,

-------
U.S. ENVIRONMENTAL PROTECTION AGENCY
NOTICE OF RESEARCH PROJECT
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
Form Approved
OMB No. 1J8-R0081
PROJECT NO. (Do not use Infs spec*)
SSIE
EPA
CBB
TITLE OF PROJECT
Analytical Services for Quality Assurance Branch, EMS Laboratory
GIVE NAMES. DEPARTMENTS, ANO OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS' ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Elaine Moore
Laboratory Operations Manager
NAME ANO ADDRESS OF APPLICANT INSTITUTION
LFE Environmental Analysis Laboratories
2030 Wright Avenue
Richmond, CA 94804
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach. (3) Current Plans andVor Progress (200 words or less. Omit confidential data).
Provide analysts services for the Quality Assurance Branch of EPA, Claclnratti, OH
over a three (3) year period.
Analyses will be performed on water samples (on a fixed - fee basis) for any of "- 150
chemical parameters .
Analyses will be performed in accordance with EPA's recommended methods.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical. SIGNATURE OF PRINCIPA
denial. etc.J OJ3. ^^
Commercial Laboratory ^jH£Xj^_n_ " VTs
FOR OFFICE USE ONLY
SUPPORT METHOD 'C.'iecfc onej TASK NO. PROJECT OFFIC



FUNDS OBLIGATED F,Y. HO. OF FUTURE YE *RS TENT ATIVELY STA
.~* ~, ASSURED BEYOND CURRENT F.Y.
. INVESTIGATOR DATE
OffvJL. 7 May 1976

:H
ue/s-r
CAN! Z ATION f ^^
RTING DATE ESTIMATED COMPLETION

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                              Form Approved
                                                                            OMB No. DS-ROOS1
                                                                   PROJECT NO. (Do not u*e thta ap*c«)

                                                                   SSIE
                                                                      CBB
TITLE OF PROJECT
    Production of Quality Control Samples
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.


    Mr. Pete Atkins,  President
NAME AND AODRESS OF APPLICANT INSTITUTION
     Environmental Control Technology, Inc.
     3983 Research Triangle  Park
     Ann Arbor,  MI  48104
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or l«»i.  Omit confident!*, data).
   In the Smithsonian Science Information Exchange, summaries of work In progress are exchanged with government and private agenda* • up-
port ing research and are forwarded to investigators who request such Information. Your summary is to be used for th*»e purposes.


    1.   Objective:

          To produce  a series of Mater quality control  samples.

    2.   Approach;

          The contractor precarss    5,000 sets of demand,  trace metal, and nutrient
          quality control samples according  to exact Instructions  supplied by  the
          Quality Assurance  Branch.

    3.   Progress

          The project 1s 90S completed.  Most of  the samples have  been received
          and verified by referee laboratories.   Current plans are to continue
          production  for the next five years.
dents/, etc.)
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR

                                           Mr. Pete Atkins
                               DATE

                                 9-15-76
                                        FOR OFFICE USE ONLY
1UPPORT METHOD (Check one)   | TASK NO.

                             1
    AGENCY ST»FF(7n(rau;ural,>
FUNDS OBLIGATED
 $13,314
               76
PROJECT OFFICER
         L.  Berg
                                                  RESPONSIBLE ORGANIZATION
                                                                             684-7326
                       NO. OF FUTURE YEARS TENTATIVELY
STARTING DATE

   10-15-75
                               ESTIMATED COMPLETION

                                 1^-13-76
EPA Form 5760-1 (7-72)    REPLACES PHS FORM IS6 AND SI-SIE 76A WHICH MAY NOT BE USED.

-------
                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                              Form Approved
                                                                            OMB No. 158-R0081
                                                  PROJECT NO. (Do not uae (fire apace)

                                                  SSIE
                                                                           CBB
  TUE or PROJECT
    Guidelines for  Sampling & Sample Preservation of Waters/Wastewaters
OIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
     Mr. Chuck Hansen. Project Officer
NAME AND ADDRESS OF APPLICANT INSTITUTION
     Envlrex, Inc.
     5103 W.  Beloit Road
                 WT
     M-iiijAiiicpp, WT   Ranni	
 SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
   [n the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private'agencies sup-
 >orting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.


     1.   Objective;

          Development of Guidelines for Sampling  and  Sample Preservation of
          waters/wastewaters.

     2.   Approach:

          The Contractor developed  Guidelines for Sampling and Sample Preservation
          of waters/wastewaters  based  upon an extensive literature review and
          questionnaires submitted  to  field personnel.

     3.   Progress:

          The contractor submitted  a final report which is currently  undergoing
          publication 1n the EPA series.   Current plans are to update the manual
          from year to year.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medlcel.
dental, etc.)
                                           SIGNATURE OF PRINCIPAL INVEST13ATOR
                                              Mr. Chuck Hansen
                                                                   9-15-76
                                         FOR OFFICE USE ONLY
   SUPPORT METHOD (Chuck an,)
                                                  PROJECT OFFICER
                                                  Edward L.  Berg
                                                              684-7326
                                                  RESPONSIBLE ORGANIZATION
FUNDS OBLIGATED
   $7,924
F.Y.
76
                       NO. OF FUTURE YEARS TENTATIVELY
                       ASSURED BEYOND CURRENT F.Y.
                                   Five
                                                            STARTING DATE
                                              6-28-74
6-28-81
EPA Form 5760*1 (7-72)    REPLACES PHS FORM !66 AND SI-SIE 76A WHICH MAY NOT BE USED.

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                            Form Approved
                                                                          OMB No. U8-R0081
                                                                 PROJECT NO. (Do rat urn, Mils apace;

                                                                 SSIE
                                                                        CBB
   Provide Technical  Services to the  Quality Assurance Branch-EMSL-C1nc1nnat1	
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT,
   Mr.  Dick Wrobel, Eastern Operation Manager
NAME AND ADDRESS OF APPLICANT INSTITUTION
   Bionetlcs Corp., 18 Research Drive, Hampton, Virginia  23666
SUMMARY OF PROPOSED WORK - (1) Objectives, (J> Approach, (3) Current Plans and/or Progress (200 words or I.... Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary Is to be used for these purposes.

    1.    Objective:

         The Technical Services  group shall support the activities of the  Quality
         Assurance Branch, EMSL-Cindnnati in such areas as:  (1)  production of
         energy related  quality  control samples, (2)  Development  of guidelines for
         Sampling and Sample Preservation  of  Water/wastewaters, and (3)  Development
         of a  computerized interlaboratory quality control program.

    2.    Approach;

         The Technical Services  Group comprised of the  laboratory director, two
         chemist, chemical engineer, computer programmer, and clerk typist, shall
         conduct studies according to task assigned.

    3     Current Plans;

         The laboratory  shall be located in Cincinnati, Ohio.   Expected  Date of
         award of this contract  is 9/29/76
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.
dental, etc.;
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                           Not awarded  to date
                                                               DATE

                                                                 9-17-76
   SUPPORT METHOD (Chock one;
FUNDS OBLIGATED

    $76,714
F.Y.

76
                                       FOR OFFICE USE ONLY
                             TASK NO.

                               1,2,3
                                                 PROJECT OFFICER
                                  Edward L. Berg     X7326
                                                 RESPONSIBLE ORGANIZATION
                                                  EMSL-Cincinnati
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                            Five
STARTING DATE
 9/29/76
ESTIMATED COMPLETION
°ATE9/29/81
EPA Form S7oO-l (7-72)     REPLACES PHS FORM 166 AND SI-S1E 76A WHICH MAY NOT SE USED.

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                            Form Approved
                                                                          OMB No. 138-R0081
                                                                 PROJECT NO. (Da
                                                                 SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        CBB
TITLE OF PROJECT
 Provide Referee Laboratory Service To The Quality Assurance Branch- EHSL - Cincinnati
OWE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 ENCOTEC- Philip Simon,  Project Manager
 LFE- Elaine Moore, Project Manager
 MRI- Dr. John Going,  Project Manager
NAME AND ADDRESS OF APPLICANT INSTITUTION
 MRI- 425 Volker Blvd.   Kansas  City, MO.  64110
 ENCOTEC- 3983 Research Park Dr.  Ann Arbor, MI   48104
 UE- 2030  Wright Avenue.  Richmond, California   94804
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plane and/or Progress (200 words ar lesa. OnUt confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such Information.  Your summary is to be used for these purposes.

  OBJECTIVE:      To provide quantitative  analytical  services for the  purpose  of
                  verifying that Quality Control  Samples prepared by other
                  contractors and in house are within predetermined acceptance
                  limits.

  APPROACH:       Three outside laboratories have been selected to  provide
                  quantitative  analytical  services  for either organics or
                  in organic water/wastevater parameters.

  CURRENT  PLAN:  Quality Control Sanples  produced  by outside contractors or in
                  house shall be continually sent to  the referee laboratories  to
                  insure that the samples  have been prepared  according to
                  specifications.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED Medical,
dental, etc.)
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                        FOR OFFICE USE ONLY
   SUPPORT METHOD (Check one)
    AGENCY STAFF (Intramural)
                                                 PROJECT OFFICER
                                                  Terry Covert    684-7326
                                                 RESPONSIBLE ORGANIZATION
                                                   EMSL - Cincinnati
FUNDS OBLIGATED
  $45,000
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.

	Three.	
                                                          STARTING DATE
EPA Form 5760-1 (7-72)
                    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED,

-------
                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                                       Form Approved
                                                                                     OMB No.  i;8-R0081
       PROJECT NO. (Da not uee ttllt space;

       SSIE
                                                                                CBB
TITLE OF PROJECT
"echnicnl "'.cvicw Services  for  IP*.  "fcroMolo^ical ''nnn.nl
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
NAME AND ADDRESS OF APPLICANT INSTITUTION

P.n.  ";ox 33276

'••ecaeur,  GA   3^33
SUMMARY OF PROPOSED WORK - (I) Objective!. (2) Approach, (3) Current Plans and/or Progress (200 words or less.  Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information.  Your summary Is to be used for theie purposes.
 f'l! X'CTTV". :       T.I >ial.itv Assurance  branch  of  ~"T.  - Cir.cinr.ntt  %as  T)rap.".rs'!

                    a
                    "V'

                    on-BBr.tlor.  o?  C^e nanual.
 mlcro')lolo<>lst,
 '.P?" , \C ',        Tcc'irlcnl rnvi™.'  services  provi'ie?' >.V' r;r. "virsr.


 C.""""": :T  f'A'T-  VtiMicattoT! of *"P.\ manual  on  ''•iayol-*s>1o'~i  ' 'on-i1
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.
dental, etc.)
                                                 SIGNATURE OF PRINCIPAL INVESTIGATOR
                                              FOR OFFICE USE ONLY
    SUPPORT METHOD rCheck orjej
                                                        PROJECT OFFICER
                                                           Jo'm  "p'.nt'TT
                                                        RESPONSIBLE ORGANIZATION
FUNDS OBLIGATED
                          NO. OF FUTURE YEARS TENTATIVELY
                          ASSUREq^BEYOND CURRENT F.Y.
STARTING DATE


1 0/T*. fjf
EPA Form 5760-1 (7-72)     REPLACES PHS FORM 166 AND SI-SIE 7SA WHICH MAY NOT BE USED.

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                              Form Approved
                                                                            OMB No.
                                                                   PROJECT NO. (Da nol use this apace.)
                                                                   S5IE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                       CBB
TITLE OF PROJECT
Development  of a Municipal Digested Sludge QC Sample
OWE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIOATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Dr.  Clark  Allen, Programs Manager
NAME AND ADDRESS OF APPLICANT INSTITUTION
Texas Instruments, Inc.
P.O. Box 5621
Pallas.  Texas  75222	
SUMMARY OF PROPOSED WORK - (1) Objective., (1) Approach. (3) Current Plan, and/or Progress (200 words or less.  Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.
 (1) OBJECTIVE:      To  develop a Municipal Digested  Sludge Quality Control  Sample.

 (2) APPROACH:       A Municipal  Digested Sludge Sample Is collected,  concentrated
                      fey  iasErirugation, freeze dried, sterllsed,  and then  charac-
                      terized by exhaustive chemical analyse*.

 (3) CURRENT FLAN:  The sludge has been  collected, freeze dried, and sterilized.
                      Che«iaal characterization followed by verification of parameter
                      concentrations should result in  a  QC Sample being available
                      la  May. 1977.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical
 dental, etc.)
                                            SIGNATURE OF PRINCIPAL INVESTIGATOR
                                         FOR OFFICE USE ONLY
    SUPPORT METHOD ("Check one;
    RESEARCH GRANT
                                                  PROJECT OFFICER
                                                    gdvard t.  Berg    68A-7326
                                                  RESPONSIBLE ORGANIZATION
                                                    EMSL - Cincinnati
 FUNDS OBLIGATED
 $25,000
F.Y.
 76
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y,
                                      1/4
                                                            STARTING DATE
                                             7/3/75
                                                               3/77
 EPA Form 57oO-l (7-72)     REPLACES PHS FORM 166 AND SI-SIE 7SA WHICH MAY NOT BE USED.

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                        OMB No. IfS-KOOSl
                                                               PROJECT NO. (Do not uee Ihla
                                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                       CCD
TITLE OF PROJECT Evaluatlon of tjje Concentrations of  Plutonium  in Humans Residing Near the
                                     OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

 E. W. Bretthauer, Chief,  Methods Development and  Analytical  Support Branch
NAME AND ADDRESS OF APPLICANT INSTITUTION
 U.S. EPA/Environmental Monitoring  and Support Laboratory
 P.O. Box 15027
 Las Vegas,  NV 89114
SUMMARY OF PROPOSED WORK - (!) Objectives, (2) Approach, (3) Current Plans and/or Progres* (200 word* or l«aa. Omit confidential data).
   In the Smithsonian Scicnrr Infurmulion Exchange, summaries of work in progress arc exchanged with government and private agencies sup-
porting research and are forwarded lo investigators who request such information. Your summary 1* to be used for theae purposes.

 Objectives:  Determine if the concentration of  plutonium  in humans residing in the
 vicinity of the Rocky Flats Nuclear Facility  are greater  than plutonium concentrations
 in humans residing  in areas not  subjected  to  plutonium contamination from a nuclear
 facility.

 Approach:   Collect  and perform plutonium analyses on autopsy  samples collected from
 humans  having resided within  a 30 mile radius of the Rocky Flats Nuclear Facility and
 from humans having  resided in other parts  of  Colorado containing no  known concentration
 of plutonium except that due  to  global fallout.  Samples  and. epidemlological data
 being collected by  the University of Colorado Medical School  and plutonium analyses
 performed by McClellan Air Force Base.
 and control areas.
                             Also collect  and analyze urine samples from stu
  Current Plans  and/or Progress:   Plutonium analyses have  been completed on lung  and
  liver samples  from approximately 50 autopsies and from 3 large urine  samples.
  Additional analyses to be performed as samples meeting established  criteria become
  available.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (
iU-r
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD (Oic.-fc mi, l     TASK NO.
W
                                PROJECT OFFICER
                                E. W.  Bretthauer '^. (&
                                RESPONSISLE ORGANIZATION
                                                       Monitoring  Systems
                                Research and Development Division, EMST
                                                                                          -L5L
 FUNDS OBLIGATED
->200.0K
76-76T
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
                                     O
STARTING DATE
  6/1/75
 EPA FoffT. 5760-1 (7-72)     REPLACED PH
-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                           Form Aftpravftt
                                                                         OMB No. J58-R008J
                                               PROJECT NO. (Da not use l/il» gpocej

                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                      CCD
 ITLEOF PROJECT   chemical  and Physical  Factors  Affecting  the Retention of Radionuclides
  •in Sm'1 anri  Rnrlf Mat.prial<;--A r.Hti'ra1 RPVI'PVI	
OIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PRbFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
  Not yet selected—see below.  Contractor is  required to  submit  "Notice of Research
  Project" to  EPA as part of contract obligation.
NAME AND ADDRESS OF APPLICANT INSTITUTION
  U.S.  Environmental Protection Agency, Office  of Radiation Programs-Las Vegas  Facility,
  P.O.  Box 15027, Las Vegas, Nevada   89114.
  (702) 736-2969 ext. 305     FTS:  595-2969 ext.  305
SUMMARY OF PROPOSED WORK - (i) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less.  Omit confidential data). ,
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to Investigators who request such information. Your summary is to be used for these purposes.

The purpose  of this project is to  critically review and  sumnarize the  pertinent
literature and experience  concerning the chemical and physical factors affecting the
retention of radionuclides in  soil  and rock material.  The  emphasis is on an  evalu-
ation of the physical-chemical reactors in soil/rock which  affect the  retention and
migration of radioactive waste materials in geologic media  in a variety of climatic
settings and discuss the significance of such  reactions  to  long-term retention.

Contract proposal evaluation currently underway.  Contractor selection in October
1976—expected that work will  begin in November 1976.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED f.
denial, etc.)
  None
                                          S1GNAT11«E OF PRINCIPAL INVESTIGATOR
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD (Check
                                                PROJECT OFFICER

                                                Rrihfrrt F.  Kg'.'fmang_ (70?)
                                                RESPONSIBLE ORGANIZATION ., -  rr>K   HDD I \/P
                                                                       U• J * trM j  Ur\r~LVi"j
                                                P.O. Rnx  15027, Las  Vegas, Nevada	89114_
FUNDS OBLIGATED
   $75K
76
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y,
None
STARTING DATE .
 (Estimated)
 November  1976
ESTIMATED COMPLETION
DATE

November 1977
EPA Form 5760-1 (7-72)     REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                            11

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                       Form Approved
                                                                      0»H No. 118-R008I
                                                             PROJECT NO. (Do not use this

                                                             SS1E
                                                                    CCD
TITLE OF PROJECT  Assessment or  tnvironmentaiimpact ana Analysis orcorvcroi  recnnoTogies
for  Radioactive Materials Associated with TH/U-233 Nuclear Fuel Cycles
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Principal  Investigator:  6. L. Simmons
                          Science Applications, Inc.
                          P.O. Box 2351
                          La Jolla, CA  92037   (714) 459-0211
NAME AND ADDRESS OF APPLICANT INSTITUTION
 U.S.  Environmental Protection Agency, Office of Radiation  Programs-Las Vegas  Facility,
 P.O.  Box 15027, Las Vegas, Nevada  89114.
 (702) 736-2969 ext. 305    FTS:   595-2969 ext. 305	
SUMMARY OF PROPOSED WORK - (I) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
  In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-

 To provide the Agency with an  independent summary and assessment of environmental con-
 siderations for the thorium  fuel  cycle, which will:

 1.   Describe the main features of thorium fuel cycle facilities, with primary emphasis
 on the HTGR cycle due to  its advanced state of development,  and secondary  effect on
 the  Light Water Breeder Reactor (LWBR) fuel cycle, as they relate to the potential  for
 adverse environmental impact.
 2.   Identify the radionuclides of environmental and public health significance asso-
 ciated with thorium fuel  cycle facilities and evaluate  the potential for and  the impact
 of long-term accumulation of these nuclides in the environment (e.g., carbon-14).
 3.   Characterize the expected  operational gaseous and liquid effluents  from each fuel
 cycle facility.
 4.   Describe the basic processes, design features, and  effectiveness of the gaseous
 and  liquid effluent control  systems currently in use or under development.
 5.   Describe the costs of the  gaseous and liquid radioactive effluent control  technol-
 ogy  used in thorium fuel  cycle facilities.
 6.   Discuss the need for  new effluent control technology which may be required to meet
 possible environmental radiation  standards.  (The possible standards to be considered
 should be equivalent to those  recently proposed by EPA  for the LWR fuel cycle.)
 7.   Compare the potential environmental impacts from normal  operations  of  thorium fuel
 cycle facilities to those from comparable LWR fuel cycle facilities and characterize
 the  significant differences.
 8.   Assess the environmental impact and analyze the control  technology  for advanced
 energy fuel cycles, such  as  mixed oxide fuels, plutonium fuel and fusion,  analyze the
 environmental risk for each  cycle.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
            None
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                     FOR OFFICE USE ONLY
FUNOS03LICATED
    $94 K
76
                                              PROJECT OFFICER
                                              RESPONSIBLE ORGANIZATION
                                                              £7J12.}_Z36=2369_exi._
None
                                                   U.S. EPA, ORP-LVF,
                        	I  P.O. Box 150271_Las__VeaasJJjeyada   89114
                        TATIVELY        STARTING DATE         ESTIMATED COMPLETION
February 1976
                                                            June  1977
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-3IE 76A WHICH MAY NOT BE USED.
                                          12

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                       OAIB No. DS-ROOS!
               PROJECT NO. (Do not use thia apace)
               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        CCD
inergy-Related Overhead Monitoring and Technqiues Development
 JIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 •ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
B. E. Arthur,  Jr.,
Environmental  Protection  Specialist
Remote Sensing Operations Branch
Remote Sensing Division
NAME AND ADDRESS OF APPLICANT INSTITUTION
EMSL-LV
P. 0. Box  15027
Las Vegas,  Nevada  89114	
SUMMARY OF PROPOSED WORK - (1) Objectives, (21 Approach, (3) Current Plan, and/or Progress (200 word, or let*. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to Investigators who request suc,h information. Your summary Is to be used for these purposes.
    Objective:
      Establish preliminary guidelines  for and demonstration of overhead remote monitorin
of Western  Energy related activities.

2.  Approach:
      Cooperative Western energy  related overhead monitoring program  between NASA and
EPA has  been established with the purpose to define,  demonstrate and develop opera-
tional remote sensor  techniques  to  rapidly monitor,  in a cost effective, quantitative
manner,  the success with which an energy-related  extraction site has been,or is being,
rehabilitated to a state suitable for  its intended or previous land  usage.  This in-
cludes the determination of environmental baselines  for the purpose  of  establishing
rehabilitation criteria as well  as  environmental  effects of mine mouth  power plants.
3.   Current Plans/Progress:
      a.   Initiate baseline information studies
      b.   Demonstration of multispectral scanner tech
niques using existing NASA system.
      c.   Utilizing  manual photo  interpretation tech-
niques of aerial photographs, perform assessments  of
environmental  impact and rehabilitation efforts.
      d.   Utilizing  multispectral  scanner ^MSS) data,
perform assessment  of environmental impact and
rehabilitation efforts.
      e.   Photo interpretation report preparation.
      f.   MSS Data report preparation.
          Prepare Western Energy  "Atlas"
          Evaluation Report.
                                                               Start
           August 1975
           August 1975
            August 1976
         December 1976
         August 1976
         7?n"?ry iQ"77—
        End
   Completed
   Completed

 August 1976
                              December 1976
September 1976
January  1977
December 1976
      JQ77	
 I DEN Tl FY PRO FES5ION ALSCHOOLr IN VO LVED (Medical
 dental, c(c.)
                                       FOFfOFFICE USE ONLY
   SUPPORT METHOD (Check one)
 FUNDS OBLIGATED
 $142K
                 76
                             TASK NO.
                             Tasks 1, 2, §3
PROJECT OFFICE
B.  Edward Art!
                                                RESPONSIBLE ORGANIZATION
                                                 RSD/EMSL-Las  Vegas
                                                         STARTING DATE

                                                           FY75
                                  FY78
 EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                             13

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                        OA1S No. 158-R0081
                                                               PROJECT NO. CDe nor us* (hia spaca)

                                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                   CCD
TITLE OF PROJECT      ™ ~                                ~~~"  "
Airborne Infrared  Earth  Reflected  Differential Absorption System for Mapping Tracer Gase:
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
John  L.  Guagliardo,  Research Chemist
RSM  (Remote Monitoring  Methods Branch)
 .SD  (Remote Sensing  Division)
 (Subobjective Title:   Energy-Related  Overhead
 Monitoring  and Techniques  Development)
NAME AND ADDRESS OF APPLICANT INSTITUTION
     EMSL-Las Vegas
     P.O.  Box 15027
     Las  Venas. NV   89114
SUMMARY OF PROPOSED WORK- (1) Objectives, (2) Approach, (3) Current Plans and/or Prat"" (200 words or less. Omit confident!*! data).
   In the Smithsonian Science Information Exchange, summaries of work In progress are exchanged with government and private agenclea sup-
porting research and are forwarded to investigators who request such Information. Your summary is to be used for these purposes.

OBJECTIVE: The objective of this project is to construct an airborne remote  sensing
device which will map  the release of a tracer gas.   The tracer will  simulate  the out-
fall  of stack gases  from a proposed  power plant.  This will aid  in selection  of sites
for  proposed power plants.

.APPROACH:   The approach is that two  CO, lasers, one  tuned on an  absorption  line of
the  tracer and the other tuned to a  "clean" region of the spectrum,  are bore  sighted
to a telescope which focuses down on an I.R. detector.  The lasers fire downward and
the  telescope collects the laser pulses reflected back from the  earth.  The difference
in the two wavelengths is related to the amount of tracers below the aircraft.
            The selection of the tracer will be made  based on laboratory studies and
a literature survey  of the environmental effects of  the tracer.

CURRENT PLAMS:  The  progress to date is that  the laboratory components have  been
assembled and tested  and the coincidences between  candidate tracers and the  CO,
laser lines are now being studied.   After this,  plans call for  the final choice of
a  tracer to be made based on the above information.   Then the ERDAS (now configured
to monitor 0.,) will  be modified, tested in the laboratory and field evaluated  in an
aircraft.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED r
 dental, etc.)
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                                   US/74
                                       FOR OFFICE USE ONLY
    SUPPORT METHOD (Check one.)
                              Task 1, 7
                                                PROJECT OFFICER
Jnhn 1
                                                RESPONSIBLE ORGANIZATION

                                                RSD/EMSL-Las  Vegas
 FUNDS OBLIGATED
          50
                   76
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED 8EYOND CURRENT F.Y.
                                                         STARTING DATE
               FY 76
ESTIMATED COMPLETION

     FY  79
 EPA Form 5760-1 (7-72)    REPLACES PHS FORM tS6 AND SI-SIE 76A WHICH MAY NOT SE USED.
                                         14

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                         Form Approfed
                                                                        O.MO A'o.  J58-ROOS1
                                                               PROJECT NO. (Dor

                                                               SSIE
                                                                       CCD
3eve1opment of a Two-Frequency Downlooking Airborne LIPAR System
OIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 ROFESSIONAL PERSONNEL ENGAOED IN THE PROJECT.
John A.  Eckert, Chief
RSM    (Remote Monitoring
oc,    r:,   ,  „    WJ T     c   a-nd Tech.nip.ues Development)
RSD    Methods Branch, Remote Sensing Division)
                                   (Subobjective Title:  Energy-Related  Overhead Monitoring
NAME AND ADDRESS OF APPLICANT INSTITUTION
       EflSL-Las  Vegas
       P.O. Box  15027
       Las Vegas,  MV   89114
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or lees. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sijp-
porting research and are forwarded to investigators who request such information. Your su:
                                                            iry Is to be used for these purposes.
3BJECTIVE:   Design,  construct and  test a two  frequency downward  looking airborne LIDAR
system.  LIDAR systems  have demonstrated capability in solving  several current pollution
monitoring problems, namely; 1) determining mixing layer height  over large  geographical
areas  in short periods of time, 2)  determining  point source  plume dimensions, and
3) determining the  dimensions of  and structure  within an urban plume.

APPROACH:   The system  design utilizes whenever  possible, off-the-shelf components
including the laser  transmitter.   Much of the  electronics control  and readout  subsystem
is implemented utilized niicroprocesser systems  thus shifting  the  construction  burden
from  hardware to software.  Much  attention is  given in the design  to operator  inter-
action  including a real  time display system for the data.

CURRENT FLAMS:  The  optical/mechanical design  phase has been  completed and the device,
minus electronics components, will be delivered  by January 1977.   Systems design work
has been completed on  electronics  portion of the device, however  actual implementation
in hardware and software will  commence after  flight testing  of the optical  system.
The  completed system will be operational  by December  1977.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
 deni.il. ere.)
                                       FOR OFFICE USE ONLY
    SUPPORT METHOD fCfiecfc one)
          CH GRANT
 FUNDS OBLIGATED | F.Y.
      60
                 76
                             TASK NO.
                             Task 2,
                                                PROJECT OFFICER

                                                John A. Eckert.
                                                RESPONSIBLE ORGANIZATION
                                                RSD/EMSL-Las Vegas
                                                         STARTING DATE
                                                               FY  75
                                                                             ESTIMATED COMPLETION
                                                                             DATE
                                                                                 FY 73
 EPA Form 5760-1 (7-72)    REPLACES PHS FO^M 156 AND SI-SI? 75A WHICH MAY NOT p£ US£D.
                                            15

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                           Form Approved
                                                                         OfiB No. I58-R0081
                                                                 •ROJECT NO. (Do not uae thlm

                                                                5SIE
                                                                       CCD
Western United
                 Quality Assurance  In Support of Energy Related A1r Monitoring 1n  the
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT,

 Dr. E. P. Parry, Rockwell  International Contract Project Officer
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Rockwell  International
 1421A West H111 crest  Drive
 Newburv  Park.  Calif.  91320
SUMMARY OF PROPOSED WORK- (1) objectives, (2) Approach. (3) Current Plant and/or Progress (200 words or I..1. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress arc exchanged with government and private agendas sup-
porting research and are forwarded tn investigators who request such information. Your summary Is to be used for these purposes.

      This  work, which Is being carried out  by contract to Rockwell  International, has
 as Its purpose the development and taplenentation of  a quality assurance program
 associated with agencies carrying  out air pollution monitoring around present and
 proposed sources of  energy In  the  Western United States. The  Program will  be carried
 out by providing on-s1te system  reviews  of  agency air monitoring operations, establish-
 ing and  operating a  performance  survey program and  provision  of  technical  assistance
 as required.  The contract was awarded 1n July and  a  lumber of on-s1te  system reviews
 have been  conducted.
 OENTIFY PROFESSIONAL SCHOOL INVOLVED f
 None
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                       FOR OFFICE USE ONLY
                                                                                  9-30-76
  ' SUPPORT METHOD (Clt.-ck am-)
    1.GENCY STAFF f
FUNDS OBLIGATED
 222K
                                PROJECT OFFICER        Phone:  (919) 549-8411,
                                 Steven H.  Brombero	Ext. 2196
76
                                                 RESPONSIBLE ORGANIZATION

                                                 gsWronmental Monitoring &  SuoDort"L,Ib/BTP
                         5 years
                                                          STARTING DATE
July 1976
                                                                              ESTIMATED COMPLETION
EPA Form 5760-1 (7-72)     REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                                              July 1981
                                            16

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        Form Approi-ed
                                                                       O.1IB ,Yo.  DS-KOOS1
                                              PROJECT NO. (Do not use rfiis spacej
                                              SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        CCD
 Energy-Related  Western/Southwestern  Regional  Air Monitoring
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
           Dr.  David H. McMelis, Deputy Director, MOD
           EPA,  ORD, EMSL/LV
NAME AND ADDRESS OF APPLICANT INSTITUTION
 EMSL-LV, U.S   EPA
 P, 0. Box 15027
 Las Vegas, NV 89114
SUMMARY OF PROPOSED WORK -  (1) Objectives, (2) Approach, (3) Current Plans and/or Progress <200 words or less. Omit confidential data).
   [n the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research arid are forwarded to investigators who request such information. Your summary is to be used for these purposes.
L.   OBJECTIVE:
    This project provides integrated and validated  air quality monitoring data (baseline
    and trend)  and assessment reports for western areas of the U.S. which will be  most
    seriously  impacted by energy-related development activities.   Emphasis is on fine
    particulates, NOX, SOX, reactive hydrocarbons,  toxic substances and visibility.  The
    geographical coverage includes the Northern Great Plains, the  Four Corners Area, oil
    shale areas  of Colorado and Utah, the Black Mesa Area of Arizona and areas of  New
    Mexico.
    APPROACH -  01I-GOING TASKS AT BEGINNING OF FY77
    a.   Maintain inventory of  existing and projected Western Energy Resource Develop-
    ment  (WEED)  pollution sources, air quality  and  meteorological  monitoring sites.
    b.   Maintain air monitoring network in the Four Corners general area and collect
    TSP and toxic substance samples.  (Contract - UTE  Research Laboratory)
    c.   Continue aircraft air  quality monitoring missions in the  WERD area to supplement
    ground-based network data.
    d.   Integrate air quality  monitoring data  and  assess impact of energy related
    activities  (Annual  Report).
    e.   Perform quality assurance audit checks on  existing energy related monitoring
    stations.
    CURRENT PLANS & PROGRESS  (TASKS TO BE INITIATED DURING FY77)
    a.   Estimate dispersion and impact of pollutants  from energy-related sources  in the
    Four Corners area.
    b.   Expand  existing monitoring networks to include sulfate and nitrate analysis.
    c.   Evaluate use of dichotomous particulate samplers for airborne particulate size
    fractionation.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (-.Medico/,
 dental, rlc. >
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                            DATE

                                                               9-27-76
                                       FOR OFFICE I
                                *$Ms£-, .  .
                                /Dr.  David N. McNeils
    SUPPORT METHOD iChtck enu)
                                               RESPONSIBLE ORGANIZATION
                                                MOD/EMSL-Las Vegas
 FUNDS OBLIGATED

  786.5K
F.Y.
 76
STARTING DATE

 FY75
ESTIMATED COMPLETION
DATE
                                                                  FY80
 EPA Form 5760-1 (7-72)    REPLACFS PHS FORM 166 AND SI-StE 76A WHICH MAY NOT BE USED.
                                          17

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               U.S. ENVIRONMENTAL, PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                               'PROJECT NO. (Da not at* «i/s spaced

                                                               53! E
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION BXCHANCB
tiTLE OF PROJECT	Monitoring the 'Impact, of Western Coal Strip lining and Oil Snale
                                                    Form Approved
                                                  OMB No. IJ8-R008I
                                                                      CCD
                  Fvtrartlnn nn
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PR!
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
                    tw quality
                    INCIPAL INVESTI
                                                     -
                                                     IGATORS OR PROJECT DIRECTORS AND ALL OTHER
                  See attached
NAME AND ADDRESS OF APPLI
                  \PPLICANT INSTITUTION
                  TEHPO-Generai  Electric Company
                  816 State Street. P.O. Drawer  QQ
                  Santa Barbara. California    93102
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach. (3) Current Plan* and/or Progreae (200 word* or less. Omit confidential data).
   I*: the Smithsonian Science Information Exchange, summaries of work in progreas are exchanged with government and private agencies tup-
porting research and are forwarded to investigators who requeat such information.  Your suairaary la to be oaed for these purpoaea.


    The primary  goal  of this study will be to ascertain the Impact of the coal
    strip mining and  oil  shale extraction and processing operations on groundwater
    quality 1n the  vicinity of Gillette,  Wyoming  and 1n an area  1n the U1nta  Basin
    of northeastern Utah, through  establishment of  a carefully designed and
    systematically  executed monitoring program.

    Simply stated,  strategy will  be  to:  (1) carefully examine and Interpret  the
    background information and data  on groundwater  quality, (2)  Inventory and
    prioritize the  potential sources and  causes of  groundwater pollution, (3)
    evaluate mobility of pollutants  from the land surface to groundwater, (4) assess
    the gaps and needs of the existing groundwater  quality monitoring program,  (5)
    design a monitoring program based on  the identification of the existing program
    deficiencies and/or the inventory of potential  sources and causes of groundwater
    pollution, (6)  implement the monitoring program at the field level  and  monitor
    its operation until 1t Is functioning smoothly  enough to be  turned over to  the
    designated monitoring agency,  and (7) prepare a final report on the results of
    the research and  monitoring effort which will serve as a guide in the design
    and operation of groundwater  quality  monitoring programs for other mining
    locations.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED Ofedfcaf,
    /, e(c.J
 University of Arizona
 Department of Hydrology
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                   .
   SUPPORT METHOD (Check ono)
PUNDS OBLIGATED
                                      FOR OFFICE USE ONLY
                                               PROJECT OFFICER
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                                               RESPONSI9LE ORGANIZATION

                                                EPft, EN&L  L.
                                                        STARTING OA-T
                                                          Jl£
                                                                            ESTIMATED COMPLETION

                                                                               9/A3/81/
EPA Form 5740-1 (7-72)    REPLACES PHS FORM 155 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                         18

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
                                                                        Form Approved
                                                                      O.IIB No. 158-R0081
                                             PROJECT NO. (Da not us, im, space)

                                             SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                     CCD
  Energy Related  Water Monitoring  Data Integration
ilVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
•ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

  Robert Thomas,  Operational Officer,  Water and Land  Quality Branch
  James Bliss,  Physical Scientist, Water and Land Quality Branch
  Lance Zeliph,  Physical Scientist,  Water and Land Quality Branch
  David McNelis,  Deputy Division  Chief,  Monitoring Operations Division
NAME AND ADDRESS OF APPLICANT INSTITUTION
  U.S. Environmental  Protection Agency
  Environmental  Monitoring and Support Laboratory-Las  Vegas
  P.O. Box  15027              Las  Vegas, NV   89114
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agendas sup-



     1)   Objectives:   Establish a water monitoring net throughout the western states  to
         monitor and assess the impact of energy resource development.

     2)   Approach:  Through the use of computer data banks,  primarily STORET  water
         mom ton ng stations that are currently in operation,  back past 1970, and  have
         reported a large  number of measured  parameters were selected for incorpora-
         tion into a primary monitoring net.  Parameters of  interest  were  identified
         and a quality assurance program is being established 'in  participating laboratori
         Historical data have been reviewed and baseline water  quality  conditions  are
         being established.   Preparation of a Western Energy Resources  Atlas is being
         accomplished  in conjunction with a similar effort on air monitoring.

     3)   -Current Plans:  Data from the primary  net stations  is  being  augmented with data
         trom other stations.  An assessment  of baseline water  quality,  trends, and im-
         pacts on a basin  by basin basis is underway.  As data  gaps,  either de-
         sired parameters,  sampling frequency,  or additional stations are  identified,
         actions will  be taken with appropriate  EPA  Regional Offices  or  other govern-
         mental  agencies to  correct them.  The  primary net will be updated  periodical-
         ly and extended into areas not presently addressed.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED f.l
dental, etc.)
                                                                                  -27-76
                                               Rf.SFQN%lS"t,E ORGANIZATION
                                               Monitoring  Operations Division
                                               EMSL-La';
                                                         Vpgas
 FUNDS O8LIGATEO
    152 K
76
                      NO, OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
STARTING DATE

   FY-75
                                                          ESTIMATED COMPLETION
                                                          DATE
                                                            FY-8.0
 EPA Form 5760-1 (7-72)
                   REPLACES PHS FORM ipfi AND SI-SIF 76A WHICH MAY NOT BE USED.

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                  Form Approved
                                                O\\B ,Vo. J58-R008/
                                                             PROJECT NO. (Do not u»« tM* space)

                                                             SSIE
                                                                 CCD
 ITLE OF PROJECT
Development of  Techniques for Remote  Monitoring of Organic  Pollution in Surface Haters
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Hichael Bristow,  Research Environmental  Engineer
RSM    (Remote Monitoring Methods  Branch)
RSD    (Remote Sensing Division)
                               (Subobjective Title:  Energy-Related
                               Overhead Monitoring and  Techniques
                               Development)
NAME AND ADDRESS OF APPLICANT INSTITUTION
      EMSL-Las  Vegas
      P.O.  Box  15027
      Las  Vegas,  NV  89114
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach. (3) Current Plans and/or Progress (200 words or less. Omtl confidential data).
  In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencle* sup-
OBJECTIVE:  The ultimate objective  of this program is to  develop an active airborne
uonitoring  system capable of providing quantitative data  on  the organic pollutional
load of surface waters.

APPROACH:   The  principal employed is  an extension of the  laboratory technique  of
spectrofluorometry.   A water sample is irradiated with ultraviolet (UV) light  of a
specific wavelength  and intensity and the resultant fluorescence emission is then
monitored using a monochromator-multichannel  detector combination.  The fluorescence
signal arises from dissolved organic  materials both man-made and natural in origin
rather from the water itself which  does not fluoresce.  However, the water molecule
emits a Raman band which for very dilute aqueous solutions of organics, has a  constant
amplitude for given  intensity of excitation radiation.  This water Raman emission band
can therefore be conveniently employed as a built in reference source with which to
compare the amplitude of the concurrent fluorescence emission.  The normalized
amplitude of the signal then provides information concprning the concentration of the
dissolved organics.

CURRENT PLANS:   A number of reports have been published recently which indicate that
this UV induced fluorescence emission is proportional to  the Total Organic Carbon (TOC)
value.  It  is planned to explore this relationship in more detail with the purpose
of establishing a firm value for a  correlation coefficient.

Based on the findings of this correlation study, an airborne laserfluorosensor will
be designed, built and tested.  This  system will have the capability of continuously
monitoring  and  recording the TOC value for the surface water below the aircraft.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
dental, etc.)
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                             9/28/76
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD 'Ch(?L-k CVHV
    AGENCY ST A FF (Intramural)
                            Task  3
    RESEARCH GR AN T
FUNDS OBLIGATED
                         PROJECT OFFICER

                         Michael  Bristnw
                                               RSD/EMSL-LV
                                                           ANI Z AT1ON
               F.Y.    NO. OF FUTURE YEARS TENTATIVELY
                 FY 7r5
ASSURED BEYOND CURRENT F.Y.

               2
STARTING DATE


     FY 75
                                                             FY 78
EPA Form 5760-1 (7-72)    REPLACFS PUS FORM iee AND SI-SIE ?SA WHICH MAY NOT BE USED.
                                          20

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                           Form Approved
                                                                         OMB No.  158-R0081
      PROJECT NO. (Do i

      SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                       CCD
 TLE OF PROJECT
 Characteristics and Potential  Impact  of Waste Waters from a Coal-Fired Power Plant..
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.                                       ,    .    ,_
                                                                      ...  at Colstnp,  MT.
 Hr. Benjamin Wake,  Administrator,
 MR. M.  K.  Botz, Water Quality Bureau
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Environmental Sciences Division
 Department of Health and Environmental  Sciences,  State Capitol
 Helena.  Montana   59601	
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.

 The principal effort in this investigation is to examine  the  production and distributioi
 of dissolved materials 1n waste water  ponds and  subsequent movement  into ground  water
 systems.   Another major objective will  be to examine corrective measures that may be
 employed  to minimize or eliminate adverse affects on ground water systems peripheral
 to the  ponds.   Ponds that will  be considered include those waste ponds near the  power
 plant and the fly ash storage pond located northwest of thecoomtiunity  of Colstrip.
 The latter fly  ash storage  pond is a large pond  used for  the  ultimate  disposal of
 fly ash.   Finally, the study will evaluate the impacts on all  beneficial water uses
 in the  aeaa.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                        FOR OFFICE USE ONLY
   SUPPORT METHOD (Check <
    AGENCY STAFF (Intramural)
                                                 PROJECT OFFICER
                                                 D. S. Earth
                                                 RESPONSIBLE ORGANIZATION
                                                  EPA/EMSL-Las Vegas
FUNDS OBLIGATED
                 76
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
STARTING DATE
  June  1975
ESTIMATED COMPLETION
Tune 1980
EPA Form 5740-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED,
                                            21

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                            Form Approved
                                                                          OMB No.  158-R008I
                                                                 PROJECT NO. (Do not ua« tht»

                                                                 SSIE
                                                                     CCD
  'Lw?uatfoncof Chemical  Quality  of Mater of Underground i-iines  in the florth Fork of....
 GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT. ....the GUnnlSOH RIVCF Coinage BflSln
   Robert Moroen, USGS, Mater Resources i)1v.  -  Colo. 01st.  Off.  (Principal  Investigator)
   O.E. Biescker, Project Supervisor (Same  as above)
 NAME AND ADDRESS OF APPLICANT INSTITUTION
   J W. Siesecker  - Denver. Colorado  80225
   U.S.G.S.  Viater Resources Division, Colorado District Office, Denver Fed.  Cent,
 SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Currant Plans and/or Progress (200 word, or less. Omit confidential data).
    In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
 porting research and are forwarded to investigators who request such information. Your summary is to be used for theae purposes.
        The purpose of this effort  Is to define the chemical quality  of water stored  in
   or discharged from underground coal  mines 1n Colorado.   The project will  be  confined
   to the  :orth Fork of  the Gunnlson  River drainage basin,  primarily  in Gunnlson and
   ^elta Counties.  The  effort will focus on development of a data  base so that
   water quality evaluations of underground coal  mining can be made.   Data will
   bo collected with reapect to pH, temperature,  specific conductance,  dissolved
   oxygen, flow, and approximately  15 cheraical  constituents.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (M
 dental, etc.)
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
    SUPPORT METHOD (Check one)
 FUNDS OBLIGATED
L.
                 76
                                        FOR OFFICE USE ONLY
                                                 D.S. Barth
                       NO. OF FUTURE YEARS TENTATIVELY
                       ASSURED 9EYONO CURRENT F.Y,
                                                  RESPONSIBLE ORGANIZATION

                                                 tSPA/EMSL-Las  Vegas
STARTING DATE

 June 1975
ESTIMATED COMPLETION
DATE
 June 1980
 EPA Form 5760-1 (7-72)     REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                             22

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                       Form Approved
                                                                     OAIB ,v0.  na-Roosi
                                            PROJECT NO. (Do not use thia apace)

                                            5SIE
                                                                 CCD
        Development of Techniques  for  Monitoring Vegetation Stress
ilVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
'ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

 Michael  Bristow, Research Environmental  Engineer  (Subobjective Title:  Energy-Related
 RSM   (Remote  Monitoring Methods Branch)            Overhead Monitoring and Techniques
 RSD   (Remote  Sensing Division)                     Development)
NAME AND ADDRESS OF APPLICANT INSTITUTION
       EMSL-Las  Vegas
       P.O.  Box  15027
       Las Vegas, HV  89114	
SUMMARY OF PROPOSED WORK- (1) Objectives. (2) Approach, (3) Current Plans and/or Progress (200 worda or less. Omit confidential data).

 OBJECTIVES:   The objective of this  program is to develop an  airborne  monitoring system
 capable of detecting and measuring  the type and degree of  vegetation  stress  induced in
 natural and  agricultural vegetation by specific atmospheric  pollutants such  as ozone,
 sulphur dioxide and nitric oxide.

 APPROACH:   The approach which has  been adapted employs the method of  fluorescence
 spectroscopy whereby changes  in  the laser induced fluorescence  characteristics of
 specific plant types will be  observed before, during and after  a  simulated pollution
 episode.
 The  measurements will be conducted  in vivo with the laser  radiation tuned to excite
 two  groups of substances in the  leaf tissue, viz. the pigments  responsible for photo-
 synthesis  and the overall cellular  and intercellular leaf  material.

 Pollutant  stress induced changes in the fluorescent characteristics will  then be obser\|ed
 anci  recorded; these are the changes in the amplitude of the  fluorescence emission, in
 both the excitation and emission spectra and in the fluorescence  decay time.

 CURRE'IT PLAMS:  The test plants  will be grown in an environmental growth chamber under
 conditions of controlled temperature, humidity and light and into which specific con-
 centrations of pollutant gases  can  be added.  Groups of specific  plant types will be
 exposed to tuned laser radiation from above in a simulated remote sensing configurator
 The  fluorescence emission is  collected by a telescope and  focused onto a monochromator
 whereby the dispersed radiation  is  detected, displayed and converted  into a DC signal
 suitable for chart recording.
 Data obtained from these measurements will then be utilized  in  the  design of an airborr
 system capable of measuring these  stress induced fluorescence changes.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
dfntnl. ere.)
                                                                          9/28/76
                                     FOR OFFICE USE ONLY
   SUPPORT METHOD .'Cfu-cfc t
 FUNDS OBLIGATED
          52
                            TASK NO.
                            Task 455
                                              PROJECT OFFICER
                                 ECT OFFICER
                                 Michael Bristow
                                              RESPONSIBLE ORGANIZATION
                                                 RSD/EMSL-LV
FY 76
                                                       STARTING DATE
                                                            FY  75
                                                                          ESTIMATED COMPLETION
                                                                          DATE
                                                                                FY 79
 EPA Form 5760-1 (7-72)
                           PH= FORM t^e AND SI-S1E 76A WHICH MAY NOT BE USFD.
                                         23

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
                                                                       Form Approved
                                                             PROJECT NO. (Do not use thla apace)

                                                             SSIE
                                                             EPA

                                                             ;ent
                        CCD
TITLE OF PROJECT Acquire from NASA and put into use  the Data Analysis System (DAS) for
              Multispectral Information,
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
     M. R. Dockter,  Electronics Systems Engineer,  Remote Sensing Operations Branch,
Remote Sensing  Division.
NAME AND ADDRESS OF APPLICANT INSTITUTION
     EMSL-LV
     P.O. Box 15027
     Las Vegas,  Nevada  89114
SUMMARY OF PROPOSED WORK - (1) objectives. (2) Approach, (3) Current Plan* and/or Progress (200 words c-r less. Omit confidential data).
1.  Objectives:
     a.  Training  of EMSL-LV Remote Sensing  Division personnel by NASA  in  the use of
the automated multispectral analysis system.
     b.  Acquire  from NASA and put into operational  use the Data Analysis  System.
     c.  Perform  analysis and prepare a final  report on completion of the  transfer of
technology.

2.  Approach:
     The training  of EMSL-LV Remote Sensing  Division personnel on the actual  DAS
with operational  type requirements will greatly enhance the NASA to EPA technology
transfer.  The  DAS was designed with the capability  to reduce a broad range of
remote sensor data and will be used to reduce  the multispectral scanner and ERTS
data for land use  mapping and water monitoring purposes.  The DAS output may be
recorded on  nine  track digital computer compatible tape for further processing,
displayed  on a  high resolution color television monitor, recorded on 9.5 inch wide
color or black  and white film, or listed on  a  high speed line printer.   A  versatile
interactive  operator control console is included to  provide complete operator-
processor  communication and control.
3.  Current  Plans/Progress:                       Start
     a.   Demonstration of technique using
existing  NASA system.
     b.   Training of EMSL-LV personnel.           October 1976
     c.   Acquire complete DAS system for          June 1976
EMSL-LV.
                          End
                          Complete

                          July  1977
                          September 1977
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,   SIGNATURE OF PRINCIPAL INVESTIGATOR
                                     FOR OFFICE USE ONLY
   SUPPORT METHOD fCI>eck <
                            Tasks 4  §  5
 FUNDS OBLIGATED
 $100K
               FY76
PROJECT OFFICER

 Marvin R.  Dockter
                                              RESPONSIBLE ORGANIZATION

                                               RSD/EMSL-LV
         STARTING DATE

           FY75
ESTIMATED COMPLETION
DATE
   FVT80
 EPA Form 57oO-l (7-72)
                                         24

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
 ITLE OF PROJECT
                                                                            Form Approved
                                                                           OMB No. W-R0081
                                        PROJECT NO. (Do not u*« Ihl, if»e>)

                                        SSIE
                                                                         CCD
           Groundwater  Research  Monitoring of Energy Related Developments
 ilVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
 •ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
         Leslie G. McMiHion,  Project officer

         Donald B. Gilmore, Project officer
NAME AND ADDRESS OF APPLICANT INSTITUTION
         U.S.  Environmental Protection  Agency
         Environmental  Monitoring and Support  Laboratory,  P. 0.  Box 15027.
         Las  Vegas. NV   89114	
SUMMARY OF PROPOSED WORK - (I) Objectives, (21 Approach, (3) Current Plan, and/or Progress (200 word, or I«B«. Omit confidential data).
   In Ihr Smithsonian Scienci' Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary Is to be used for these purposes.
         Objective:
         Approach:
          Progress:
To direct the  research and monitor ,the progress
of contracts under this program.

Three  groundwater basins will be  studied by applying
theoretically  developed monitoring strategies and
the  results developed  into guidelines for monitoring
groundwater quality.

A contract has been  signed with TEMPO for an oil
shale  mining and processing project in the Uintah
Basin, Utah and a strip coal mining area in the
Powder River Basin.

                                        FOR OFFICE USE ONLY
    SUPPORT METHOD t
       54K
                  76
                                                  PROJECT OFFICER
                                                  D. B.  Gilmore,  L.  G. McMillion
                                                  RESPONSIBLE ORGANIZATION
                                                  MSD/EMSL-LV
                       ASSURED BEYOND CURRENT F.Y.

                                3
                                 STARTING DATE

                                   FY76
ESTIMATED COMPLETION
DATE

     FY78	
 EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND Si-S'E '6» WHICH MAY NOT BE USED.
                                          25

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                         Form Approved
                                                                        OMB A'*
                                               PROJECT NO. (Do not u«e Ihl9 space)

                                               SSIE                   	
                                                                       CCD
 TLE OF PROJECT
         Groundwater Research Monitoring of Energy  Related Developments
ilVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   Dr. T.  E.  Larson -  Principal Investigator
NAME AND ADDRESS OF APPLICANT INSTITUTION
   Illinois State Water Survey
   P. 0.  Box 232
   Urbana,  IL  61801
SUMMARY OF PROPOSED WORK -  (1) objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.
   Objective:
   Approach:
   Current
    Progress:
To develop a statistical base for  evaluating the  necessary  frequency of
sampling and analysis  for data collection designed to assure  accuracy  in
determining short-term trends in water quality  in streams and lakes.
Conversely, the average percent deviations for  sampling intervals
greater than daily will be determined.

Daily  sampling, both grab and composite, will be  conducted  at 6 stream
sampling sites and 3 lake sites.   These samples will be analyzed for 17
parameters.  Data will be related  to water-shed size, stream  flow
characteristics, physiographic features, and climatology.   For lakes,
the data will be related to size,  depth, area,  characteristics of the
drainage area, and climatology.
Sampling has started  and analyses  are being made.   Other than analyses
data,  no output is  expected until  the end of the project.  Sampling will
continue for 2 years.   At the end  of the sampling  period,  the average
percent  deviations  will be determined from the median of the  one day
sampling frequency  and the 10 and  90 percentiles when 2, 4, 7,  14,
the 5-day work week,  and the Monday, Wednesday,  Friday intervals are
used.  Deviations from the 1-day annual daily mean will also  be
determined.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED r
 dental, etc.)

            NONE
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                             OATE


                                                             9/28/76
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD (Check oncj
   $150K
 76
                                                PROJECT OFFICER
                                                 Donald B. Gilmore
                                                RESPONSIBLE ORGANIZATION
                                                 MSD/EMSL-LV
      NO. OF FUTURE YEARS TENTATIVELY
      ASSURED BEYOND CURRENT F.Y,

              1.5
                                                         STARTING DATE
                                           9/76
                                                                             ESTIMATED COMPLETION
                                                                             DATE
                                                                                   3/78
 EPA Porn* 5760-1 (7-72)    REPLACES i
                                                      MAY NOT BE USED.
                                          26

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                           Form Approved
                                                                         OMB No. I5S-ROOS1
   PROJECT NO. fOo nol use Ihi, space)

   SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                EPA
                                                                       CCD
 ITLE OF PROJECT                           ~~""™	
   Groundwater Research Monitoring of Energy Related Developments
 1IVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 'ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   Dr.  Richard Tinlin, Principal Investigator.
NAME AND ADDRESS OF APPLICANT INSTITUTION
   General Electric-TEMPO
   P. 0.  Drawer  QQ
   Santa Barbara,  CA  93102
SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach. (3) Current Plans and/or Projress'(200 words or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.
   Objective:  Development  of a groundwater monitoring model  and strategy  that will
                be applicable to any  strip coal mining and oil  shale mining and pro-
                cessing area.

   Approach:   Two groundwater basins  will be intensively studied by applying a
                theoretically developed monitoring strategy and the results developed
                into a guideline for  monitoring groundwater quality in each of the
                above areas.

                Approximately 60%  of  the effort will  cover groundwater in the strip
                coal mining  area on the east flank of the Powder River Basin where
                there is  mine-mouth power generation and railroad export and there  are
                proposed  coal gasification and liquefaction projects  as  well as a pipe-
                 line slurry  proposal.

                The remaining 40%  of  the effort will be in the Uintah Basin, Utah
                 around Tracts U  and  U,  where  there is a proposed mining and processing
                                 a       b
                project.

    Current
        Plans: A contract with GE-TEMPO has been executed and baseline  data covering
                 identification of  all ongoing  monitoring and  relevant groundwater
                 information  is ongoing.  A monitoring strategy is expected  about 6/77
                 with immediate implementation.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.
 dental, etc.)
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                                9/28/76
                                        FOR OFFICE USE ONLY
    SUPPORT METHOD (Check
                                                 PROJECT OFFICER
                                                   Leslie  G.  HcMillion
                                                 RESPONSIBLE ORGANIZATION
                                                   MSD/EMSL-LV
 FUNDS OBLIGATED
    S22SK
                  76
                       NO. OF FUTURE YEARS TENTATIVELY
                       ASSURED BEYOND CURRENT F.Y.
                               3
                                                          STARTING DATE
10/76
                                                                              ESTIMATED COMPLETION
6/81
 EPA Form 5760-1 (7-72)    REPLACES PHS FORM ise AND si-sie 76A KHICH MAY NOT BE USED.
                                         27

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U.S. ENVIRONMENTAL PROTECTION AGENCY Form Approved
OAlfl ,\o. 158-R0081

PROJECT NO. (Do not use this tp»ce)
NOTICE OF RESEARCH PROJECT SSIE
	 	 	 	 ' EPA
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE CCD
TITLE OF PROJECT
Groundwater Research Monitoring of Energy Related Developments
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Dr. Wayne Wyatt, Principal Investigator
NAME AND ADDRESS OF APPLICANT INSTITUTION
Texas Water Development Board
Box 13087, Capitol Station
Austin. TX 78711
SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach. (3) Current Plans and/or Progress (200 word, or lot. Omit confid.ruial data).
Objective:
Approach:
Current
Plans:
Validation of an EPA-developed groundwater quality monitoring
strategy.
A groundwater basin in East Texas that includes huge lignite
reserves, oil and gas reserves, and major developments of these
reserves will be studied. Identification of polluted areas will be
made, the source identified, and the transport pathway determined.
The first six steps of the monitoring strategy will be applied and
the first phase of the strategy identified.
The proposed contract has been forwarded to the Texas Water
Development Board. This Board proposes to furnish $83K of the
$138K cost of the project. Present plans exist for a continuation
that will implement and operate the monitoring strategy to
determine the validity of the strategy.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical, SIGNATURE OF PRINC PAL INVESTIGATOR DATE
NONE Q./2S/76

FOR OFFICE USE ONLY
SUPPORT METHOD iChcck une; TASK NO. PROJECT OFFICER
•AGENO STAFF
X *E = =T.ATED C
rtn,,m,u,M .Leslie U. McMillion

RESEARCH GRANT MSD/EMSL-LV
FUNDS OBLIGATED
S55K
F.Y. NO. OF FUTURE YEARS TENTATIVELY STARTING DATE ESTIMATED COMPI FTinu
ASSURED BEYOND CURRENT F.Y. DATE COMPLETION
76 2 10/76 11/78
EPA Form 5760-T (7-72)     REPLACES  PHS FO^M  156 AND S'-SIE 76A WHICH MAY NOT BE USED.
                                                        28

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               U.S. ENVIRONMENTAL PROTECTION AOENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THB SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                           Form Approved
                                                                         CMI8 No. 158-R0081
PROJECT NO. (Do not use this space)
sste
                                                                    OCD
flfLEOF PROJECT	
 Potential Radioactive Pollutants Resulting From the 3zpanded Program:
OIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Project Director:  Robert M. rtodden        Other Professionals:  Thomas 0. Peyton
 Project Supervisor:  Philip J. Dolan                               Robert V. Steele
 Project Leader:   Hong Lee                                           Ronald K. White
NAME ANO ADDRESS OF APPLICANT INSTITUTION
 Stanford Research. Institute
 333 Ititvenswood Avenue
 Jlenlo Park, California 94025
SUMMARY OF PROPOSED WORK - (1) Objective*. (2) Approach, (3) Current PU<1» and/or Progress (200 word! or less. Omit confidential dau>.
   In tho Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
potting research and are forwarded to investigstors who request such information. Vour summary Is to be osed for those purposes.
 Objective:  To identify  and document the potential radioactive pollutants that
              could result from the expanded  energy program and for  which' quality
              assurance  programs mist be provided.

 Approach:   The research approach is to gather data on conventional and nuclear
              energy system facilities.and operations, on the radionuclides in
              conventional and nuclear fuels  and the releases of these radionuclides
              to the environment;, to yrvl"0  the pathways of these  radionuclides  to
              human exposures; and to compute the potential amount  of the various
              radiomxclide releases and associated hazards for a fev selected
              plausible  alternative expanded  energy programs.  The  energy systems
              for which  radionuclide releases will be assessed, from resource
              extraction to final  waste disposal, include coal, shale oil, geo-
              thexoal, and various nuclear systems.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.
dental, etc.)
                                          SIGNATURE OF /RINCIPAI/rNVESTlGATOR
   SUPPORT METHOD (Check one)
    AGENCY STAFF (Intramural)
FUNDS OBLIGATED
                                       FOR OFFICE USE OtViff
              OATS

              February 9, 1S7G
                                                 PROJEC'T
                                                 RESPONSIBLE QRGANl ZATION
                       NO. OF FUTURE YEARS TENTATIVELY
                       ASSURED BEYOND CURRENT F.Y.
                                                          STAR-ING DATE
              ESTIMATED COMPLETION
              OAT-
 EPA Form 5740-1 (7-72)    REPLACES PHS FORM 166 ANO SI-SIE 76A WHICH MAY NOT 3E USED.
                                          29

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                           Form Approved
                                                                         OMB No.  UB-R0081
                                                                PROJECT NO. (Do not u»a thim efMC*-)

                                                                SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        CCD
TITLE OF PROJECT
 Energy-Related Radiological  Pollutant  Monitoring and Techniques Development	
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.


 B. Robinson, Supervisor Radiological Surveillance Environmental Control
NAME AND ADDRESS OF APPLICANT INSTITUTION
 U.S.  ERDA Mound Laboratory
 Monsanto Research Corporation
 P.O.  Box 32      Miamisburg.  OH  45342
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plan* and/or Progress (200 word* or less. Omit confidential data).
   In lh<- Smithsonian Scicnci* liifurinullon Exchange, summaries of work in progress are exchanged with government and private agencies sup-
 ortinft research and are forwarded In investigators who request such information. Your summary Is to be used for thaee- purposes.

 Objective:  Conduct research on the development  of  techniques to monitor potentially
 hazardous effluents and  emissions from nuclear  fuel cycle facilities.

 Approach:   Develop or evaluate methods for monitoring Plutonium and  uranium in water
 and americium in soil.   Recommend methods which  best  meet established  criteria and
 conduct and evaluate results of interlaboratory  collaborative tests  of these methods.
 This  includes the development of appropriate reference materials  for calibration and
 analysis.

 Current Plans and/or Progress:  A method for measuring plutonium  in  water is presently
 undergoing collaborative testing.  Efforts are underway to develop reference methods
 for uranium in water and americium in  soils.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (
 N/A
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR     DATE
                                        FOR OFFICE USE ONLY
     1GSEARCH GO AN T
 FUNDS OBLIGATED
                76-76TI
                                                 PROJECT OFFICER  3.  Rob±nson,
                                                 Surveillance  F.nvtronmenfal
                                                 RESPONSIBLE ORGANIZATION
                       NO. OF FUTURE YEARS TENTATIVELY
                       ASSURED BEYOND CURRENT F.Y.
STARTING DATE

 7/1/76
ESTIMATED COMPLETION
DATE
                                                                               6/30/77
 EPA Form5760-J (7-72)    REPLACES PHS FORM 166 AND SI-SlE 76A WHICH MAY NOT BE USED.
                                            30

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
    PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        Form Approved
                                                                      OAIB Ho. 1S8-ROOS1
     PROJECT NO. (Da not ua« thlt space)

     SSIE
                                                                     CCD
ITLG OF PROJECT
Snergy-Related Radiological Pollutant Monitoring and Techniques Development
WE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS Ofl PROJECT DIRECTORS AND ALL OTHER
ROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.

E. W. Bretthauer, Chief,  Methods Development and Analytical Support Branch
 AME AND ADDRESS OF APPLICANT INSTITUTION
U.S. EPA/Environmental Monitoring and  Support Laboratory
P. 0.  Box 15027
Las Vegas, NV  89114
iUMMARY OF PROPOSED WORK - (I) Objectives. (2) Approach, (3) Current Plans and/or Progress. (ZOO words or [ess. Omll confidential data).
  In the Smithsonian Science Information Exchange, summaries of work in progreas are exchanged with government and private agencies sup-
lortinif research and are forwarded to investigators who request such information. Your summary Is to be used for these purpose*.

Obj ective:   Conduct research on  the  development of  techniques to monitor  potentially
hazardous effluents  and emissions  from nuclear fuel  cycle facilities.

Approach:  Characterize the physical  and chemical  properties and radiation levels of
plutonium and other  actinide discharges from a mixed uranium and plutonium oxide fuel-
fabrication facility.   Recommend and  collaboratively test methods for  monitoring
plutonium, uranium and thorium in  soil, air and water,  including the development of
appropriate reference  materials for calibration.

Current Plans and/or Progress;  A  tentative EPA reference method for the analysis of
plutonium in soil  has  been developed  and collaboratively tested.  A second method
recommended by ERDA  for the analysis  of plutonium  in soil is currently undergoing
collaborative testing.  Efforts are underway to develop a reference method for the
analysis of plutonium  in air.  Future plans are to begin the evaluation of currently
available methods  for  measuring uranium and thorium  in the environment.

      The physical  and  chemical properties and radiation levels of plutonium and other
actinide discharges  are being characterized under  contract from samples collected at
a  mixed, uranium-plutonium oxide  fuel fabrication  facility.  Stack  sampling has been
completed and the  samples are currently being analyzed through an Interagency Agreement
with the U.S. Air  Force Technical  Applications Center.   Environmental  air, soil, and
vegetation samples are also being  collected and analyzed.
 OENTIFY PROFESSIONAL SCHOOL INVOLVED ;
 N/A
                                     .J,   SIGNATURE OF PRINCIPAL INVESTIGATOR
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD fCd.-i-/, ..».<•)     TASK NO.
 FUNDS OBLIGATED

   4  43.9K
F.V.

76-761
                                                PROJECT OFFICER

                                                G   R.  Morgan
                                                Epaearrh and
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                 pjtT-s-e-lon/FMqT-TV
STARTING DATE

   10/30/74
                                                                            ESTI
                                                                            DATE
                                                         12/30/80
 EPA For--' 5760-1 (7-72)    REPLAY F< PHS FL?"M if* AND S'-^'F ^6 & A-HICM MAY NOT ee us
                                            31

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        Form Approved
                                                                      OMB No.  758-R008/
                                                             PROJECT NO. (Do not 11*9 this *P0C*>

                                                             SSIE
                                                                      CCD
TITLE OF PROJECT
     Energy-Related  Radiological Monitoring  Quality Assurance
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENOAOED IN THE PROJECT.

     A. N. Jarvis,  Chief,  Quality Assurance  Branch
     D. G. Easterly,  Chief, Intercomparison  and Calibration Section
     E. L. Whittaker,  Chief, Monitoring Guidelines and Standardization Section
NAME AND ADDRESS OF APPLICANT INSTITUTION
     USEPA/Environmental  Monitoring and  Support Laboratory
     P.O. Box 15027
     Las Vegas,  Nevada  89114
portinR I
        ) veyclti,  LNt±vaua  O7XX4
SUMMARY OF PROPOSED WORK - (I) Objectives, (2) Approach. (3) Current Plans and/or Progress (200 ward* or less. Omit confidential dale).
        lilhsoni.in Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup*
        trch and are forwarded lo investigators who request such information. Your summary la to be used for these purposes.

Objectives   To  develop and maintain  a quality assurance program which continuously meets
the needs  of those laboratories having  responsibility  for  radiation monitoring  in the
environs of  nuclear reactors and nuclear and fossil fuel extraction and processing
facilities.   This  includes the distribution of calibrated  samples and reference material:
cross-check  studies, instrument development, and the publication of instrument  quality
control procedures and pertinent guidelines.
Approach  An ongoing radioactive standards calibration and distribution program and a
laboratory intercomparison studies program have been in operation at EI1SL-LV since 1972
and are continuing on schedule.  However,  monitoring of the exploration, development,
and utilization of energy sources will  require a continual and expanded need for both
naturally-occurring and man-made radionuclides for use in  the  preparation of standard
reference  materials, standard reference samples, and intercomparison studies.
Current Plans/Progress  Standard reference materials,  calibrated samples, and guidelines
required for the analysis of samples obtained by monitoring activities in the vicinity o:
nuclear facilities, fossil fuel extraction and utilization activities, and geothermal
sites will continue to be made available.
     A  "state-of-the-art" beta counting system has been designed, constructed,  is
operational  and is in the final testing stages.
     Guidelines describing calibration  and quality control procedures for radiation
monitoring using gamma spectroscopy  and liquid scintillation counting have been prepared
     An  IAG  was negotiated with NBS  for the production of  300 radium-228 standards and
for studies  to assure our continued  traceability measurements to the NBS.
FUNDS OBLIGATED

  $102.8K
               F.Y.

                 76
                                               RESPONSIBLE ORGAN,Z.T,ON    :,OnitOrin
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            U.S. ENVIRONMENTAL PROTECTION AGENCY
              NOTICE OF RESEARCH PROJECT
                                                              Form Approved
                                                             O.VB No. 15S-R0081
PROJECT NO. (Da not i»* Mill ipmct>

SSIE
    PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                        CFA
 rLEOF PROJECT

         Analysis of Aerosol_Data
 WE NAMES. DEPARTMENTS. AND OFFICIAL TITLES Of PRINCIPAL INVESTIGATORS OR PROJECT OIRtCTOHS AND ALL OTHER
 ROFE3SIONAL PERSONNEL ENGAGED IN THE PROJECT.
         Dr Kenneth A.  Hardy
         Associate Professor of Physics
         Department of Physical Sciences
         Florida International University
NAME AND ADDRESS OF APPLICANT INSTITUTION
         Florida International University
         Tamiami Trail
         Miami. Florida   33199	
SUMMARY OF PROPOSED WORK - (I) Objectives. (2) Approach, (3) Current Plans and/or Progress (200 words or les». Omit confidential data).
, . In the.Smilhsonian Science Information Eichang«. Bummariea of work in progress are exchanged with government and private agencies sup-
»ortfng recearclt and are forwarded to investigator* who. raqwst such information. Your summary ia to be used for these purpo»es.

   The aerosol Research Branch of the Environmental Protection Agency
   with the assistance of the Aerosol Group  at Florida  International
   University and Florida State  University collected samples of urban
   aerosols in Miami,  St. Louis  and Pittsburgh during the  summer  of  1975.
   Preliminary data  generated through proton induced x-ray emission,
   PIXE, have been submitted to  the Environmental Protection Agency  for
   some of  the samples collected during this time.  This proposal is to
   support  the reduction of this data.  The  analysis of the data  will  be
   done in  cooperation with R. K. Patterson  of the aerosol research
   branch.   The tasks  necessary  for this data  reduction include a)
   coordinate the irradiation of the remaining samples  from St. Louis  and
   Pittsburgh on the Van de Graff accelerator  at Florida State University;
   b)  Extract the elemental concentrations from the spectral data
   generated in a; c)  Prepare plots of the elemental concentrations  as a
   function of time  or particle  size, whichever is appropriate; d)
   Prepare  reports which will attempt to explain the measured aerosol  con-
   centrations by considering available meteorological  emission inventory
   and chemical balance data.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED f.W
 denfaf. etc.;
            DATE

            16 June  76
                                 FOR OFFICE USE ONLY
   SUPPORT METHOD (Cheek one)
 X
                                         PROJECT OFFICER
                                                    7
                                         RESPONSIBLE ORGANIZATION
                                           ESRL,  RTF
 FUNDS OBLIGATED
              76
                   NO. OF FUTURE YEARS TENTATIVELY
                   ASSURED 9EYONO CURRENT F.Y.
                                                 STARTING DATE
            ESTIMATED COMPLETION
            DATE
                                     33

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              U.S. CNVIRONMCNTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
 Form Appravtd
.VB NO. ns-noost
                                                              PROJECT NO. (Oa not u»« Ihlm apace'
                                                              SSIS
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                    CPU
TITLE OF PROJECT   Alrcralt Measurements in support ot Jfroject iviial l, ivudwest
                Interstate Sulfer Transformation and Transport
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENCASED IN THE PROJECT.

                See Attachment #1
NAME AND ADDRESS OF APPLICANT INSTITUTION
                Meteorology Research, Inc.
                464 West Woodbury Road
  	Altadena.  California 91001
SUMMARY OF PROPOSED WORK - (I) Objectives. (2) Approach. (3) Current Plans sod/or Proems (200 words or less.  Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup*
porting research and are forwarded to Investigators who request such information. Your summary is to be uaed for these purposes.

         The purpose of the 1976 MISTT study is to  extend the results of previous
         studies to cover larger distances from the  sources and obtain.more de-
         tailed knowledge of the chemical processes occurring in polluted air. The
         aerosol formation processes as well  as gaseous plume  chemistry will be
         the subject of continued study.  Conversion rates  and mechanisms identified
         earlier need to be verified under a  variety  of meteorological conditions. The
         aerosol chemistry of the urban and power plant plumes will be examined us-
         ing new techniques which will yield information on substances other than sul-
         fate.  In addition to refining our understanding of the chemical processes, the
         1976 program will attempt to  better, define  the  regional transport and accumu-
         lation mechanisms at work in the Eastern United States.  The project will be
         expanded from the immediate St.  Louis area to include the study of pollutant
         accumulation and transport in synoptic scale,  slow moving, stable air masses.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED f.Wedicsf.
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                            DATE
                                                                              28 June  1976
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD CCftcci on
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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                            Forwr Approved
                                                                           QMS ,Vo. 138-ROOS!
                                          PROJECT NO. (Do not utt Oil* tpfc

                                          SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                     CFB
 ITLEOF PROJECT
               Determine Che Character  and Origin of Aerosola and Development of Fine
               Particle Methodologies
OIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES Of PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
 '..  E.  Heffelfiager Chemistry Department, Associate Manager, Analytical,  Physical and
          Atmospheric Chemistry
 '.  W.  Jones Chemistry Department,  Associate  Manager, Organic Chemistry
 ).  Mendenhall Researcher
 1.  Chase Researcher	
NAME ANO ADDRESS OF APPLICANT INSTITUTION
          Battelle  Columbus Laboratories
          505 King  Avenue
   	Coluabus  OH 43201	
 UMMARV OF PROPOSED WORK- (1) Obj.ctlv... (J) Approach. (3) Currant Pbtu and/or Pratt*** (200 word* or Ic...  Omit corJId~nU»l data).
   In tha Smithsonian Seltnea Information Exchanga, aumraariwa of work In progra»a ara axchancad with (ov«ram«nt and private agancl«» *up-
portlnc r***arch and ara forwardad to invastlcacor* who raq.uast aueh Information. Your aununary ia to ba uaad for th«aa pvrpoa«a.
1.   Objectives

     The  objective of the project is to provide the analytical chemistry and smog
     chamber studies support necessary to determine the character and origin of aerosols,

2.   Approach

     The  approach  is to apply all inorganic  and organic analysis techniques necessary to
     characterize  aerosols with  regard to  elements, ions, and  compounds.  In addition
     smog charnber  studies will be carried  out in  order to illucidate  the processes of
formation of aerosols from gaseous products.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED f.W.d/c./,
 .dmntmt, arc.j
                                            SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                         DATE

                                                         10/11/76
                                         FOR OFFICE USE ONLY
    SUPPORT METHOD (Cftaefc one)
           1 ST Apr (7nframti»O
                                                   PROJECT OFFICER
 FUNDS OSLIGATEO
I NO. OF FUTURE YEARS TENTATIVELY
 ASSURED BEYOND CURRENT F,Y*
                                                            STARTING DATE
                                                                                ESTIMATED COMPt.ETtOf1
 EPA Form 5760-1 (7-72)
                     REPLACES PHS FORM 166 ANO SI-SIE 7SA WHICH MAY NOT 9E USED.
                                             35

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        Form Approved
                                                                       OMB No. 118-KOOSl
                                                              PROJECT NO. (Do not urn* thl* t

                                                              551E
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                      CFB
TITLE OF PROJECT Perform a Literature Survey on Present Emissions  from Various Stationary
Sources  and to conduct Smog Chamber Studies  of Emissions Found	
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL. INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Dr.
Mr.
Dr,
Dr,
    J. E.  Sickles, II, Project Leader, Environmental Measurements Department
    C. E.  Decker, Project  Supervisor, Environmental Measurements Department
    W. C.  Eaton, Chemist,  Environmental Measurements Department
    L. A.  Ripperton, Principal Scientist, Environmental Measurements Department
Mr. R. S.  Wright. Environmental Scientist. Environmental Measurements Department
NAME AND ADDRESS OF APPLICANT INSTITUTION
Research Triangle Institute
P.O. Box 12194
Research Triangle Park.  NC  27709
SUMMARY OF PROPOSED WORK - (1) Objactivaa. (2) Approach. (3) Currant Plan, and/or Proiraaa (200 norda or laaa. Omit confldaatlal data).
   In tha Smithsonian Sclanca Information Exchanfa, aunmarlaa of work in profraaa ara axchaflfad with covanunaot and private aganeiaa sup-
porting rexaareh and ara forwardad to tnvaatlgatora who raquaat auch Information. Your luminary 1» to ba uaad* for thaaa purpoaaa.
      The increasing  demand for energy  In the face of shortages of available fuels has
resulted in the  emergence of new processes  and technologies  aimed at increasing the
energy output from fossil fuels.  As the requirement for  energy increases,  the impact:
of such processes on air quality must  be evaluated.  The  operations for consideration
are shale oil production, petroleum refining,  and coal mining, combustion,  and gasifi-
cation.   Conventional mobile and stationary combustion sources have been  the major
contributors to  the  photochemical pollution burden in many areas.  Composition and
emission rate information coupled with oxidant-forming potential from smog  chamber
investigations will  enable EPA to assess the future impact of new energy  sources on
air quality.

      The objectives  of  this investigation are:

      •    To perform a  literature survey to gather Information on
           composition and rates of emissions of organic,  nitroxy,
           and sulfoxy emissions from various operations of the
           emerging energy technologies;  and

      •    To conduct smog chamber studies of the atmospheric chemistry
           of emissions  from production and  refining operations related
           to coal and oil-shale conversion  and petroleum  refining.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED• CMadleaf.
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD (Check <
     OENCY STAFF (lilt t.
                                               PROJECT OFFICER
                                               Robert
                                                      Farland
                                               RESPONSIBLE ORGANIZATION
                                                EPA,
FUNDS OBLIGATED  F.Y.    NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED SEYOND CURRENT F.y.
                                                        STARTING DATE
                                                                                      MPLETION
EPA Form 5740-1 (7-72)    REPLACES PHS FORM I So ANO SI-SIE 7SA WHICH MAY NOT BE USED.
                                           36

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        t'nrm {
                                                                       o.tt.t NO.
                                        PROJECT NO. (Da nof u»r «i/«

                                        SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                  CFB
TITLE OF PROJECT                  	
'ower Plant Plume and Sulfate Study in Complex Terrain
   e NAMES, 06PARTMENTS, AND OFFICIAL. TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
John U Swift,  Vice Pres./Office of Environmental  Kgmt. (Project Manager)
tobert C.  Koch, Sr. Research  Scientist, Office  of Environmental  Mgmt.(Principal  Invest.)
touglas J.  Pelton, Research Scientist, Office of Environmental  Mgmt.fDiractaiVFielcU
Paul H. Hwang,  Research Scientist, Office of Environmental Mgmt.(     Meteorologist)
IIAME AND ADDRESS OP APPLICANT INSTITUTION
GEOMET,  Incorporated
15 Firstfield Road
Gaithersburg, Md. 20760
SUMMARY OF PROPOSED WORK -  (I) Objective.. (2) Approach. (3) Curt.nl Plan, and/or Progress (100 word, or less. Oral! confidential data).
   In iKe Smithsonian Science Information Exchange. summaries of work in progress arc exchanged with government and privato agencies sup-
porting research end «ro forwarded to Investigators who request such information. Your summary is to be used lor those purposes.
1.0  Objectives:  (1)  Creation of reliable  data describing atmospheric behavior of sul-
fur oxide and nitrogen oxide emitted from a specific large power  plant in complex  terrait ;
(2) Appraisal  of current  knowledge of plume behavior under similar  conditions; (3)  Im-
provement of capabilities for predicting such  behavior.

2.  Approach:   (1) A six-month literature survey will  be conducted  of current knowledge
of atmospheric behavior of  plumes from tall stacks  in complex  terrain, including conser-
vative dispersion and  sulfate transformation;  plus  an appraisal of  the adequacy of avail-
able modeling techniques  for predicting sucr; c'ansvjor. m Field  measurements will  be
conducted for a year,  using fixed and mobile ground plus airborne monitoring at the
700 MW coal-fired Clinch  River Power Plant  in  the Appalachian  Mountains at Carbo,  Virginia
Parameters observed continuously will include  meteorology; NOX and  SOX emissions;  concen-
trations  over time and space of NO/, SOg^ulfates and 03 in the plume. (3) Improved
modeling  techniques for describing plume behavior in complex terrain and sulfate trans-
formation will be developed upon data and the  Clinch River literature survey.

3.  Progress and Plans: Work began October  31,  1975.  Field measurements begin June 1975,
with completion May 1977.   Analyses and modeling will  be completed  October 1977 with
Final Report in early  1978.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED tl
 oVnl»f. ftp.)

     N.A.
                   SIGNATURE OF PRtNO.

                    JOHN L.  SW
                    Project  Manager
                                                                   107C.
                                      FOR OFFICE USE ONLY
   SUPPOHT METHOD fC/n'c* one}
          ITAI-'F flii«/;imnrnO
    MGSEARCH CHAN 1
                         PROJECT-OFFICER
                            t. Montgomery
                                               RESPON5IOLE ORGANIZATIO
 FUNDS OBLIGATED
                 It*
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CUHRENT F.Y.
                                                        STARTING OAT
                                    /0/c
 EPA FormS760-l (7-72)    REPLACES PUS FORM !«,& ANO SI-SIE 76A WHICH MAY NOT BE USED.
                                         37

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                         form Approved
                                                                        OMB No.  l}t-ROOal
                                                               PROJECT MO. fO» nor off Into

                                                               S5IE
                                                                     CFB
VITLE OF PROJECT "Quantative Oiesdcal Analysis of Particulars by Raman Spectroscopy:
                                            and gnmplTf.ar.iona''
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   Miiton Kerkar, Dept.  of Chemicstry, Clarkson Professor

   Oerry D. Cootte,  Dept. of Chemistry, Bsaearch Assistant Professor

   Research Associate (to be  appointed)
MAME ANO AOORESS OF APPLICANT INSTITUTION
    Clarkson College of Technology,  Division of Research, Potsdam, Sew York 13676
SUMMARY OF PROPOSED WORK -  (I) objective*. (2) Approach. (3) Current Plan* •Ad/or Prefrees (200 word* Of !•••. Ottlt confidential date).
   In Itw Smilheonian Science Information Exeh«nf«, Buram«ri«« it work in progr«» an *xchan(«d with (ovvrnmittt mn± prlvat* af»ncU» tap-
parting rcxearch and ara forwarded to investigators who r*qu«xt sucK infonmtion.  Your •iwunary IB to b« u**d for m««e pwpoee*.

        We propose to perform calculations,  using  a recently developed theory, to
   estimate the effect of particle size and  refractive index on the Raman  scattering
   cross sections for molecules comprising all  or  a constituent part of snail particles.
   These calculations will be coordinate with experimental work at the National Bureau
   of Standards directed toward the analysis of molecular species contained in small
   particles.  The numerical studies will permit extension of the present  technique  for
   qualitative analysis of particulates to a more  quantitative  basis, since to this
   point no theory has been available which predicts the dependence of the total Raman
   signal on particle size, shape, refractive index and orientation with respect to  the
   illumination and collection directions.   Calculations to  elucidate these dependencies
   may also lead  to estimation of  the distribution of the molecular species within the
   particle (e.g.  uniform distribution throughout  the particle  or concentration in a
   surface layer).   It will also provide information which could lead to improvements
   in the design  of the present instrumentation.   Theoretical studies will be undertaken
   to extend the  present theory to nonspherical particles and to nonuniform light sources.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED r.
t/eri(..l, clr.l
        Science and Engineering
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
   SUPPORT METHOD '.Ctn-ek on.-)
    AGENCY STAFF n,ittfintnral>
                                      FOR OFFICE USE ONLY
                                  2-4
FUNDS OBLIGATED
                                                                      J".
                                               RESPONSI9LE ORGANIZATION
                                                        STARTING DATE
                                                                            ESTIMATED COMBUSTION
                                                                            DATE
                                                                               8A'7/77
EPA Form 57o
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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                       Form Approved
                                                                     OMB No. H8.R0081
                                              PROJECT NO. (Da ma u<« Mm apace)

                                              SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                CJA
TITLE OF PROJECT
IDENTIFICATION OP COMPONENTS OF ENERGY-RELATED WASTES AMD EFFLUENTS
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Dr. E. D. ?ellizzarl, Senior Chemist anci Project Director - Chemistry and  Life Sciences
                                                              Group
Dr. R. Bandy,  Senior Chemist - Chemistry and Life Sciences Group
Dr. R. Jeffcoat,  Chemist - Chemistry and Life Sciences Group
NAME AND ADDRESS OF APPLICANT INSTITUTION
Research Triangle Institute, P. 0» Box 12194,  Research Triangle Park, N. C.   27709
SUMMARY OF PROPOSED WORK - (1) Objectivoa. (2) Approach. (3! Current Plan! and/or Proireaa (200 word, or lea,..  Omit confidential data).
   tn the Smlthaonlan Sclanee Information Exchange, euramariea of work In prograas are exchanged with government and private agencies «up-
porttnc research and ar« forwarded to Investigators who request such Information. Your summary la to be used for theaa purpoaes.
     The  long  term objective of the proposed  research is to identify  substances in
wastes and effluents from energy-related processes.  Information developed from this
program will assist researchers who are concerned with control technology and monito-
ring techniques and the health and ecological effects of such energy-related  pollution.
The proposed work is divided into three phases.  Phase A consists of  a  state-of-the-art
summary and work planning which constitutes contacting EPA personnel  to determine which
energy—related solid waste and aqueous  effluents have been analyzed for the purpose of
Identifying and measuring pollutants  and which current contracts and  projects will pro-
vide further Identification.   It will also consist of judging the reliability of exis-
ting information and the probability  of accumulation of adequate data from current con-
tracts and projects using pre-selected  criteria.  This information will be collated and
summarized in  a report for EPA.  The  report will identify gaps in existing and  probable
future data on chemical elements and  volatile organic compound in solid wastes  and
aqueous effluents from coal mines, oil  refineries, oil-shale processors,  coal-fired
power  plants,  coal liquefaction and coal gasification plants.  Phase  B  consists of se-
lecting sampling sites based on the recommendations from the report prepared  in Phase
A.  The specific alma of Phase C consist of:   (a) development and setup of analytical
protocol, (b)  qualitative and  quantitative analyses for elements and  organics in
aqueous and solid wastes from  the selected energy-related processes,  and  (c)  the inter-
pretation and  collation of data obtained.

     The  proposed methods of analyses for the elements consists of flameless  atomic ab-
sorption  for mercury and spark source mass spectrometry for the qualitative and quanti-
tative analysis for all elements through uranium in the periodic table  of the elements
excepting oxygen, helium, hydrogen, neon, krypton, zeon, radon, nitrogen, carbon and
mercury.   Volatile and semi-volatile  organic  compounds in water and solid samples will
be identified  primarily by gas-liquid chromatography/mass spectrometry/computer analysis
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Werffcal,
 doflfa/, ere.)
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                      FOR OFFICE USE ONLY
                                                     404  546-3186	
                                                    '„.    Ann  Alford
   SUPPORT METHOD CCheck one)
                            TASK NO.


                                 ID
                               RESPONSIBLE ORGANISATION       U.S.  EPA    I
                               Environmental  Research Lab., Athens,(
 FUNDS OBLIGATED
         000
F.Y.
 76
                     NO. OF FUTURE YEARS TENTATIVELY
                     ASSURED BEYOND CURRENT F.Y.
                            O
                                                       STARTING DATE
ESTIMATED COMPLETION
DATE y
   V7?
 EPA Form 5760-1 (7-72)
                   REPLACES PHS FORM 166 AND SI-SI E 76A WHICH MAY NOT 3E USED.
                                              39

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                    U.S. ENVIRONMENTAL PROTECTION AGENCY
                      NOTICE OF RESEARCH PROJECT
                                                                                  Form Approved
                                                                                OMB No. IfS-ROOSI
                                                                       PROJECT NO. (Do not uee this space;

                                                                       SSIE
          PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                           CSB
     TITLE OF PROJECT
     Su1 fate and nitrate  Analyses of Northern Great Plains  Particulate Matter
     GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
     PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
     NAME AND ADDRESS OF APPLICANT INSTITUTION
     Montana Uept of Health and  Environmental Sciences,  Colorado  Dept of Health,  South
      Dakota  Environmental Protection  Department,  and Uorth Dakota Dept  of Health
     SUMMARY OF PROPOSED WORK -  (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 word* or less.  Omit confidential data).
        In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies aup-
     porting research and are forwarded to Investigators who request such information. Your summary is to be used for these purposes.


      An analysis of hi-v91ume  sampler filters at 40 sites in Colorado,  Montana, North
      Dakota  and South  Dakota will be performed  to determine $04  and ^63 concentrations.
      ;M1 samples collected on  an every-sixth-day basis will be analyzed for o..e year.
      The respective State Air  Pollution  Control  Agency Lab is performing the  analyses.
     IDENTIFY PROFESSIONAL SCHOOL INVOLVED C.Wed/cal,
     dental, etc.)
                                                SIGNATURE OF PRINCIPAL INVESTIGATOR
                                             FOR OFFICE USE ONLY
        SUPPORT METHOD fCheck one;
                                        1-6
                                                      PROJECT OFFICER
                                                      Cooper H. Wavman
                                                      RESPONSIBLE ORGANIZATION
                                                      SPA  -  Region VIII
 Funds Estimate*-
    I$215,000
IV	
                      76
                            NO. OF PUTURE YEARS TENTATIVELY
                            ASSURED BEYOND CURRENT F.Y.
                                                                STARTING DATE
1975
                    ESTIMATED COMPLETION
30,  1977
tTTFunds approximate not for Citation. '»• ANDSI-SIETSA WHICH MAY NOT BE USED.
                                                 40

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                               Form Approved
                                                                             OMB NO. ns-Kooai
                                                   PROJECT NO. (Do not uoe tftls space.)

                                                   SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                            CSC
'ITLE OF PROJECT
 on Shale Area Meteorological  Data Analyses
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Roger Nelson
NAME AND ADDRESS OF APPLICANT INSTITUTION
 CPU Limnetics
 11435 West 48th Avenue
 Wheat Ridge, Colorado   80033
SUMMARY OF PROPOSED WORK - (1) objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less.  Omit confidential date).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to Investigators who request such information. Your summary is to be used for these purposes.

 Upper air meteorological  data will be  purchased  Ifbm the  National Climatic Center
 in  Asheville, fJC,  for all MS recording sites in EPA, Region VIII.  The  temperature,
 wind  speed and wind direction data collected at  Grand Junction,  Colorado will  be
 compared  with like data obtained near  the  Colorado  Federal  oil shale  lease tracts.
 A determination  of the  representativeness  of obtaining  upper air data  for 15 days
 in  the central portion  of each  quarter will  be made.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
dental, etc.)
                                            StGNATURE OF PRINCIPAL INVESTIGATOR
                                         FOR OFFICE USE ONLY
    SUPPORT METHOD (Check one)
    AGENCY STAFF (Intrarmiral)
                                   1 A-l
                                                   PROJECT OFFICER
                                                   RESPONSIBLE ORGANIZATION
                                                    OEA,  EPA,  Region VIII, Denver
 FUNDS OBLIGATED

    55 K
F.Y.
76
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y,
                                                             STARTING DATE
                                         3/76
ESTIMATED COMPLETION
DATE
     7/76
 EPA Form 5760-1 (7-72)     REPLACES PHS FORM 166 AND SI-SIE 764 WHICH MAY NOT BE USED.
                                               41

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                             Form Approved
                                                                           OMB No.  I58-R0081
                                                                  PROJECT NO. (Do not uae thta apace)
                                                                     CSD
T'fech°nicaTAss1 stance 1n the  Review  and Revision of  Alluvial  Valley Floor  Designations.
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.                                         ...lit 56160160
 Jack Schmidt
Western Coal  Strip
               Mines
NAME AND ADDRESS OF APPLICANT INSTITUTION

 State of Montana,  Helena.  Montana   59601
SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach. (3) Currant Plane and/or Progress {200 words or lias. Omit confidential data).
   In the Smiths on tan Science Information Exchange, summaries of work in progress are axe hanged with government and private agencies sup-
porting research and are forwarded to investigators who request such Information. Your summary !• to be used for these purposes.

 The objective of this effort Is  to  provide  technical  assistance 1n  the review and
 revision of alluvial valley floor designations at selected surface  coal mines 1n
 the Interior West  of the United  States.  Appropriate  background material will be
 obtained and reviewed.   An  evaluation will  be made  of the EPA aerial imagery program
 with respect to alluvial valley  floorscriterla and  interpretation.   A report will
 be prepared which  reviews existing  alluvial  valley  floor research to date,  and re-
 commendations will  be established for future research and policy.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical
dental, etc.)
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
   SUPPORT METHOD (Check one.)
    AGENCY STAFF (Intramural)
    RESEARCH GRANT
FUNDS OBLIGATED
                76
                                        FOR OFFICE USE ONLY
                                                 PROJECT OFFICER
                                                  Cooper H.  Wayman
                                                 RESPONSIBLE ORGANIZATION
                                                   EPA-Region 8
                       NO. OF FUTURE YEARS TENTATIVELY
                       ASSURED BEYOND CURRENT F.Y.
                                                           STARTING DATE
EPA Form 5740-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                          42

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        Form Approved
                                                                      OHB No. 118-R0081
PROJECT NO. (Dor

SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                  CSD
TITLE OF PROJECT
Reconnaissance Happing  of Alluvial Valley Floors in Northeastern Montana
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Jack  Schmidt, Printipal  Investigator
NAME AND ADDRESS OF APPLICANT INSTITUTION
Montana Department of Health and Environmental Sciences
Helena, Montana  59601
SUMMARY OF PROPOSED WORK - (1) Objective*. (2) Approach, (3) Current Plans and/or Progress (200 words or lesa.  Omit confidential data).
  In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such Information. Your summary is to be used for these purposes.
The evolution of a  new Federal Coal  Leasing  Program has  placed new amphasis  on mining
the shallower coal  deposits of the western United States.   A critical variable to be
considered is the  competition of the shallow coal raining operation with other estab-
lished  land uses.   The competition has  been  especially focused at the existing agri-
cultural iand uses  within alluvial valley  floors.  Alluvial  valley floors are combin-
ations  of geologic, hydrologic and land use  factors, usually agricultural land use, thai
because of the  storage of shallow ground water, are important to the economic well-
being of agricultural  operations in  the semi-arid western United States.  However,  the
specific interactions  of the geologic,  hydrologic and biologic functions of  such  low-
land cjrainagesareas are not sufficiently represented In  existing sourcesoof  data  to
permit certain  identification without field  investigations of situations which may
differ (differ  in  the  climatologlcal, geologic, hydrologic, and biologic sense) from
those areas recently  Investigated (southcentral/eastern  Montana, northeastern Wyomino).
Experience has  shown that reconnaissance mapping on a county-basis can be accurately
extrapolated to larger drainage basins  to  project the extent of potential conflicts
•between established agricultural land uses of the alluvial  valleys and the surface
mining of coal.  Selected proposals  for federal surface  coal mining legislation and
regulations address alluvial bailey  floors and protection of the functions th-.r^of  to
differina degrees.  Montana has shown great  interest in  assessing the relative important
6f the  alluvial valley floors.  This effort  will therefore involve a reconnaissanca
mapping of surface driinages in a three-county area of northeastern Montana  (Oawson,
Richland, and McCone  counties).  In  addition, appropriate measures will  be identified
to  protect the  Mater-dependent sesources of  agriculturally-important alluvial valleys
where such valleys  have potential to be affected by the  coal resource.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
dental, etc.)
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD fCfieck one;
                                               PROJECT OFFICER
                                               Cooper H. Wayman
                                               RESPONSIBLE ORGANIZATION
                                               EPA-Region 8
FUNDS OBLIGATED  F.Y.
                76
                     NO. OF FUTURE YEARS TENTATIVELY
                     ASSURED BEYOND CURRENT F.Y.
                                                        STARTING DATE
             ESTIMATED COMPLETION
             DATE
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                          43

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                          Ftirm ApprtHH'tl
                                                         OAlfl Nn, liH-HOOHl
                                                               PROJECT NO. (Do not uae ihl, ,p,,c,,

                                                               5SIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                  EPA-IAG-D6-E681-BCG
 TITLE OF PROJECT
 Development of  Ultrasensitive Ammonia Monitor
 GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

 Hrubesh, L.W.,  Principal Investigator, Chemistry Department
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Lawrence Livermore Laboratory
 P.O.  Box 808
 Livermore, Ca.  94550
                                 Phone:   (415) 447-1100 ext. 8816
SUMMARY OF PROPOSED WORK - (1) Objective!. (2) Approach, (3) Current Plan* and/or Program* (200 words or left*. Omit confidential data).
   In the Smithsonian Science Information Exchange, ftummarlea of work In progress arc exchanged with government and private agencies cup*
porting research and arc forwarded to Investigators who request such Information. Your summary la to be used for these purpose*.
      The objective  is to increase the sensitivity of existing ammonia gas detectors by
preconcentration  techniques.

      Our Study win  result in the selection of  a preconcentration  method which can
satisfy the  following requirements:
          1)  Extend  the detection limit of the  microwave instrument  to 1 ppb in air.
          2)  Operate in a automatic mode.
          5)  Be field useable.
      After an exhaustive investigation of trapping materials for ammonia we have
concentrated our  efforts on two  techniques.  One is  the use of a chromatographic
packing material, chromosorb 104, as  a trap for ammonia.  The other  is cryogenic
cooling to -125° C by liquid argon.   Both of these show the highest promise for quan-
titative trapping of ammonia.   The cryogenic technique so far has  shown to be  the
best trap while the  chromosorb  104 lends itself most readily for automatic field use.
We are continuing to compare these two techniques for optimum use.
      We have designed and constructed an integrator/preconcentrator  module which
atomates the trapping, flashing, and  integrating functions.  The operation of this in-
strument is  described in a report UCID 17174,   An instrument has been delivered to the
Environmental Protection Agency,  Research Triangle  Park, North Carolina, where it will
be tested by Dr.  William McClenney with other ammonia detectors such as chemilumen-
scent and laser opto-acoustic.
      Our work will  continue to  determine quantitative reproducibility and lower
detectable limits.   Then we will  test the combination of preconcentrator/microwave
detector for field use and report on the results.
 DENTIFV PROFESSIONAL SCHOOL INVOLVED (Medical.
dental. tffc.J
 NA
                                                                                27/10/76
                                      FOrTOFFICE ufe ONLY
   SUPPORT METHOD CC/ipck <
                                               PROJECT OFFICER
                                                Gregory T. D'Alessio
                                               RESPONSIBLE ORGANIZATION
                                                AAES/ERDA
FUNDS OBLIGATED  F.Y,
 $25K
1976
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
  Three
STARTING DATE
 June 1975
ESTIMATED COMPLETION
°*T5une  1980
EPA Form 5760-] (7-72)
                   REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                           44

-------
                  U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
                                                                             Form Approved
                                                                           OMB No. 1J8-R0081
                                                PROJECT NO. (Do not am, IMm space)
                                                SSIE
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                 EPA-IAG-D6-E681-BCG
    ITLE OF PROJECT
        Optical Absorption Properties of Sulfate Aerosol
   GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
        P.  T.  Cunningham -Principal Investigator - Chemist
        R.  Kumar, Engineer
        S.  A.  Johnson,  Scientific Associate
   NAME AND ADDRESS OF APPLICANT INSTITUTION
        Argonne National Laboratory
        9700 So. Cass  Avenue
        Argonne. T.L    60439	
   SUMMARY OF PROPOSED WORK- (!) objectives, (2) Approach, (3) Current Plan, and/or Progress (200 words or less. Omil confidential data).
     In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government end private agencies sup-
   porting research and are forwarded to investigator! who request aucK information. Your luminary Is to be used for these purposes.

             The objective of this program is to develop  techniques  and procedures  for
         the measurement of sulfate and acid sulfate in atmospheric  aerosol material.
         The approach is based on the determination of the infrared  absorbtion  spectra
         or other characteristic  spectra of  the aerosol material and its derivatives.
         Progress during the past year has included development of procedures that  pre-
         serve the acidity of samples collected on filters during  the samples prepa-
         ration steps prior to obtaining the  spectrum.  The infrared characterization
         technique has  been compared in the  field with other methods for the measurement
         of sulfate  and acidic sulfate aerosol.  Current  plans are to continue  to develop
         new techniques and improved procedures for sulfate aerosol  characterization.
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
   denial, ere.)
               N.A.
                                                            IPAL INVESTIGATOR
                                                               10/28/76
                                          FOR OFFICE USE ONLY
      SUPPORT METHOD (Check one)
                                                   PROJECT OFFICER
                                                   Hodge  R. Wasson
                                                   RESPONSIBLE ORGANIZATION
                                                   ERM
Funds Estimated
  I $30,000
76
       NO. OF FUTURE YEARS TENTATIVELY
       ASSURED BEYOND CURRENT F.Y.
                                                            STARTING DATE
ESTIMATED COMPLETION
DATE
                                                                                 June  1976
Funds approximate not for Citation. i66 AND SI-SIE TSA WHICH MAY NOT BE USED,
                                               45

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                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
                                                         Form Approved
                                                        o»n NO. ns-Rooai
                                                                 PROJECT NO. (Do not uM rill.

                                                                 SSIE
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                   EPA-IAG-D6-E681-BCG
   TITLE OF PROJECT
   Optimize Filters and  Stack Probe for Aernsnl  Sourrp Sampling
   GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES Of PRINCIPAL INVESTIGATORS OB PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   H.  J.  Ettinger, Industrial  Hygiene Group,  Group Leader
   M.  I.  Tillery, Industrial  Hygiene Group, Aerosol Studies Section, Section  Leader
   J.  C.  Elder, Industrial  Hygiene Group, Aerosol Studies  Section, Staff Member
   NAME ANO ADDRESS OF APPLICANT INSTITUTION
   Los Alamos Scientific  Laboratory
   P.O.  Box 1663, MS 486
   Los Alamos, New Mexico  87545
                                  phone  information:
                                  FTS 843-6145
                                  com'l  505/667-6145
   SUMMARY OF PROPOSED WORK- (l) Objectives. (2) Approach, (3) Currant Plans and/or Progress (200 word* or lea*.  Omit confidential data).
      In the Smithsonian Sci#nce Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
   porting research and are forwarded to investigator* who request such Information. Your summary Is to be used for these purpose*.

         The objectives of this project are evaluation of existing particulate,  stack
    sampling procedures  (EPA  Method 5), including  probes and filter media, and development
    of an extractive stack sampler without  the limitations of  the  existing sampler.   This
    sampler should measure total particulate mass  and particle size characteristics  con-
    veniently, rapidly and accurately.

         Evaluation of existing stack probes and filter media  has  been  initiated  Deposi-
    tion  of monodisoerse  dye  aerosols and polydisperse fly ash and glass bead aerosols in
    several size ranges was measured under  representative flow (14 and  23 Jt/nrin) and temp-
    erature (140-160°C) conditions.  Deposition  in the sampling probe ranged from  94% using
    a  13  urn mmd glass  aerosol  to 1.5% with  a 1.2 um dye aerosol.   The probe nozzle (parti-
    cularly the 0.25 inch  diam nozzle) is the  major deposition point.

         Collection efficiencies of two commonly-used glass fiber  filters against  monodis-
    perse fluorescing  dye  aerosols are being measured at 11, 21, and 28 Z/min and  160°C
    conditions.  Mass  measurements by a fluorometric technique of  aerosol material collectec
    on a  backup reference  filter provides data for calculating efficiency of the test fil-
    ter.   Preliminary  filter  efficiencies range  from 94 to 99.9%,  somewhat lower than ex-
    pected.  Confirming experiments are planned.
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.
   dental, etc.)
                         SIGNATURE OF PRINCIPAL INVESTIGATOR


                            // /g-vi^v-i -y  / ^ I Li*.
                                         FOR OFFICE USE ONLY
      SUPPORT METHOD fChec* onoj
Funds Estimate*
    $65, 000
                                                 PROJECT OFFICER
                                                   Hodge  R.  Wasson
                                                 RESPONSIBLE ORGANIZATION

                                                  ERDA
F,Y.

76
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F,Y,
STARTING DATE


  1975
                                                                             June 1977
Funds approximate not for Citation, iss AND SI-SIETSA WHICH MAY NOT BE USED.
                                             46

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                                                                                              ,1
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                             O.Mfl No: DS-ROOSl
                                       PROJECT NO. (Da not use Ibi, space;
                                       SSfE
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                       EPA-IAG-D6-E681-BCG
   PITLE OF PROJECT
    Studies to determine SOj and 304  in Power Plant Stack  Emissions
   GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
   PROFESSIONAL PERSONNEL ENGAOEO IN THE PROJECT.
    Leonard Newman,  Applied Science.
          
-------
U.S. ENVIRONMENTAL PROTECTION AGENCY Form Approved J
OMB No. I18-ROOS1
PROJECT NO. (Do not uae this 9P»C»)
NOTICE OF RESEARCH PROJECT SSIE
EPA
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE EPA -IAG-D6~E681~BCG
TITLE OF PROJECT
Seta Gauge 8 XRF Analysis for Aerosol Sampling Studies
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Joseph M. Jaklevic, Electronics Engineering, Project Engineer
Fred 5. Goulding, Principal Investigator
NAME AND ADDRESS OF APPLICANT INSTITUTION
Energy Research & Development Administration for
Lawrence Berkeley Laboratory
University of California
SUMMARYE51F'F-R4p5c7sED(^jU
porting research and are forwards
1) Objectives: Tc
2) .Approach: To i
ana:
bets
on i
J) Current Plans:
J'-VWW?)'»ctweai^2> Approach, (3) Current Plan* and/or Progress (200 words or less. Omit confidential data).
'ormation Exchange, summaries of work in progress are exchanged with government and private agenclea sup-
d to investigators who request such information. Your summary Is to be used for these purpoaes.
» improve the neasureaent of participates in air.
Tirther develop X-ray fluorescence methods for elemental
ysis of participates and to develop an accurate snail
i gauge to measure the total mass participates deposited
'liters.
To continue the improvement in the methods developed in
earlier years.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical. SIGNATURE OF PRINCIPAL INVESTIGATOR DATE
denial, ere.;
10/11/76
FOR OFFICE USE ONLY,-.
SUPPORT METHOD (Chuck
AGENCY ST A FF (Intromura

RESEARCH GRANT
nds Estimate* F'Y'
$120,000 76
one> TASK NO. PROJECT OFFICER
— | Hodge R. Wesson
RESPONSIBLE ORGANIZATION
ERDA
Xfsu°RFEDUBTEUY'oENSECAURRVEENTTFATYl.VELY ST4RT'N° °"* g1^*"" """'-".ON
Sept. 1976
"Tunds approximate not for citation, '« ANO S'-5IE '«* *HICH MAY NOT BE USED.
                                             48

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
                                                               Form Approved
                                                              OMB No. 158-R0081
PROJECT NO. (Do not u,. M, space)

SSIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                       ip"A~
   FiTt
                                                       EPA-IAG-D6-E681-BCH
              Development or  Aqueous Jifxiuent Instrumentation  and Methods
  for  Energy Related Sources - (Multi-component)
  ilVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS
 GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF'PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER	
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT. Dr . VelniCr A . FaSSCl, Deputy  DlrBCtOr
 (515-294-2112); Dr.  Harry J.  Svec, Assistant Program Director;  Dr. James
 Fritz,  Chemist; Dr.  Colin Crisswell, Assistant  Chemist; Mr. J.  Richard,
 Associate Chemist; Dr. Joseph Katzenburger, Postdoctoral; Mr. Walter L.
 Sutherland, Assistant  Physicist
 NAME AND ADDRESS OF APPLICANT INSTITUTION
                                  Ames Laboratory, USERDA
                                  Iowa State University
                                  Ames,  Iowa 50011
 SUMMARY OF PROPOSED WORK - (1) Objective!. (2) Approach, (3) Current Plan* and/or Progress (200 worda op leaa. Omit confidential data).
   In the Smlth«onUin Science Information Exchange. summaries of work in progress are exchanged with government and private agencies mup-
 porting research and are forwarded to investigators who request »uch Information. Your aummary is to be used for theae purposes.

 The broad objectives of  this study are  to develop the basic science,
 the  investigative methods and the hardware  so  that the demanding
 analytical requirements  associated with the characterization  of organic
 and  inorganic pollutants in aqueous  effluents  from energy generating
 sources can be met in a  viable practical manner.   The specific
 effluents on  which attention will be focused  include waste  or scrub
 water effluents from the mining,  processing, and  conversion of coal,
 acid mine drainage liquids, leachates and runoff  from spent solid
 waste piles,  and ground, .surface,  and estuary  waters in the vicinity
 of  coal operations and geothermal energy plants.   The specific projects
 are  (a) critical comparison of activated carbon and macroreticular
 resins for  the isolation and characterization  of  trace organic
 pollutants  in water;  (b) development of chelating resins with
 macroreticular organic matrices  for  the isolation of heavy metal
 pollutants  from estuary  waters;  and  (c) expansion of the project on
 development and application of an inductively-coupled plasma  analytical
 system for  the simultaneous multielement determination of trace
 elemental pollutants.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
 dental, etc.)
             N/A
                                              RINCIPAL INVESTIGATOR
                                    7. A. Fassel,  Deputy Director
               11/22/76
                                  FOR OFFICE USE ONLY
    SUPPORT METHOD (Check one)
 unds Estimate*
 |$113,000    76
                                         Hodge R. Wesson
                                          PROJECT OFFICER
                                          RESPONSIBLE ORGANIZATION
                                         ERDA
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                                                 STARTING DATE
           ESTIMATED COMPLETION
           DATE
           June 1977
Funds approximate not for Citation, s AND SI-SIE 76A WHICH MAY NOT BE USED.
                                      49

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
  TITLE OF PROJECT
  Farm .-\fipnn-efl
OVB No.
                                                                PROJECT NO. (Do not use this apace)

                                                                SSIE
  OWE NA,_
  PROFESSIOi
        Tns±-mjmen±ni-.ism rmA Vto-Oinfa fnr> Oumiatepizing  Aqueous Effluents  from Ml Shale
        MRfrjOfJMpTUENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
                :SOMNEL ENGAGED IN THE PROJECT.
        B. R.  Clark
        Analytical Chemistry Division
  NAME AND ADDRESS OF APPLICANT INSTITUTION
        Oak Ridge National Laboratory
        P. 0. Bos:  X
        Oak Ridge,  Tit  37830	
  SUMMARY OF PROPOSED WORK- (I) Objectives, <2> Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
     In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
  porting research and are forwarded to Investigators who request such information. Your summary is to be used for these purposes.

         Plans to develop  a large scale oil shale  processing technology in the Green
    River  formation must include surveilance of  related  effluents.  This project  focuses
    on the development of  methods for the chemical  characterization of  aqueous effluents
    associated with the retorting processes; attention is being  given principally to
    organic and trace metal components.
         Organic components are  being analyzed by  several  methods under development.
    First, major organic components are analyzed directly by gas  chromatography with no
    sample pretreatment.   Minor  and trace organic  components are  removed from  the samples
    by adsorption on activated carbon, neutral macroreticular resins  and ion exchange
    resins.   Profiling of  components is carried  out using gas chromatographic methods
    employing standard and specific element detectors.  Fractionation of the organic
    mixture is followed by identification and quantification of  some  specific molecular
    species,  e.g., phenols, polycyclic aromatic  hydrocarbons and  some nitrogenous bases.
    Trace  metals will be determined simultaneously by  spark source mass spectrometry.
         Samples of retort product  water were obtained from the  Laramie Energy Research
    Center.   Activated carbon extraction is being  carried out on  this and other aqueous
    samples from a coal conversion  process to gain some  detailed  knowledge of extraction
    efficiencies for compound classes using this technique.  When the extraction  procedure
    is sufficiently developed, instrumentation for automation of  this step will be  developed
    concernitantly with chemical  characterization studies.
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
                                           SIGNA^JRE OF PRINCIPAL INVESTIGATOR
     SUPPORT METHOD fC/iccfc yncj
      RESEARCH GHANT
Funds Estimate*
    $60,000
                  76
                                        FOR OFFICE USE ONLY
                                   la.
                                                 PROJECT OFF
                                                 RESPONSIBLE ORGANIZATION
                                                  ERDA
                                                          STARTING DATE
     ESTIMATED COMPLETION

            1976
Funds approximate not for citation.'" AKlr
                                               50

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                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                           Form Approved
                                                                         OMB No.  118-ROOH1
                                             PROJECT NO. (Da no

                                             SSIE
                                             EPA

                                              EPA-IAG-I6-E681- BCH
     LE OF PROJECT
   Instrumentation  and Methods for  Characterizing Aqueous  Effluents from Oil Refining Souro
   GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
    ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

        B. R. Clark
        Analytical Chemistry Division
   IAME AND ADDRESS OF APPLICANT INSTITUTION
         Oak Ridge National Laboratory,P.O.  Box X,0ak Ridge,  TN  37830
   SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach. (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
     In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-

          Oil  refining  processes have associated effluents which may be detrimental to'
     health and/or  environment.  Although many gaseous effluents have long been identified,
     detailed knowledge of aqueous effluent streams requires additional  scrutinity in
     order to assure  a  minimum hazard.
          The scope of  this project  includes the chemical characterization of organic
     components in  process waters admitted to  the environment.  This will  be accomplished
     by  the development and application of methodology suitable for  the extraction,
     concentration, fractionation and chemical  characterization of the  organic components.
          Plans and present efforts  involve  the adaptation of extraction procedures for
     the efficient  separation of organic compounds of all important  classes.   A large
     number of major  organic components can  be analyzed directly by  gas chromatography
     with no sample preparation.  Minor and  trace organic components are removed and
     concentrated by  adsorption on activated carbon, macroreticular  resins or ion exchange
     resins.  Whole sample and fraction profiles will be carried out employing gas
     chromatographic  techniques with standard  and specific element selective detectors.
     Specific compound  analyses may  be made  with special concern for the levels of phenols
     and polycyclic aromatic hydrocarbons.
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED C,Vcdictj/,
   dcntnl, ffc.)
                                            SIGNAtrtRE OF PRINCIPAL INVESTIGATOR
                                         FOR OFFICE USE ONLY
      SUPPORT METHOD .Chcefr one)
Funds Estimate*-
   [$33.000
76
                                    Ib.
                                                  PROJECT OFFICER
                                                   Hodge R.  Wasson
                                                  RE5PONSI8LE ORGANIZATION

                                                   ERDA
     NO. OF FUTURE YEARS TENTATIVELY
     ASSURED BEYOND CURRENT F.Y.
                                                           STARTING DATE
ESTIMATED COMPLETION

°june  1976
        approximate not for citation.
                                                 51

-------
                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          Fnrm Afiprorfd
                                                                         OMR A'o. J58.R008J
                                                                PROJECT NO. (Do not uaa thi* spacej

                                                                sste
                                             EPA

                                              EPA-IAG-A-E681-ZCB.
   TITLE OF PROJECT                                          '

   Instrumentation and Mehtods for Characterizing Aqueous Effluents  from Geothermal Sources
   GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

         B.  R. Clark
         Analytical Chemistry Division
   NAME AND ADDRESS OF APPLICANT INSTITUTION
         Oak Ridge  National  Laboratory
         P. 0. Box X
         Oak Ridge, TN  37830	
   SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach. (3) Current Plans and/or Progress (200 words or [ess. Omit confidential data).
          Geothermal steam and water  sources may provide a substantial energy resource.
    Large scale production could  have  a significant health  and/or environmental  effect
    since a large number of salts and  compounds have been identified in effluents  from
    several operating facilities.
          The scope of this project includes the development of methodology for  the rapid
    analysis of trace metals in brines and steam condensates and a screening of organic
    compounds carried in aqueous  effluent streams.  Spark source mass spectrometry on
    whole and treated samples will  be  employed in the identification and quantification
    of metals.   Charcoal extraction  and concentration of organic compounds will  be
    followed by chemical characterization and profiling using gas chromatographic  tech-
    niques.  Known hazardous compounds, e.g., phenols and polycyclic aromatic hydrocarbons,
    will  be sought in these preliminary studies.
   IDEM TIFY PI
   dfnC.il. pfc.>
                          . INVOLVED Medical,
                                           SIGNAURE OF PRINCIPAL INVESTIGATOR
      SUPPORT METHOD IChcck one)
       1GENCY STAFF (7/r
       JECOTIATED CONTRACT
Funds Estimate*
  I  $20,000
76
                                        FOR OFFICE USE ONLY
                                   1C
                                                 PROJECT OFFICER
                                                  Hodge R. Wasson
                                                 RESPONSIBLE ORGANIZATION
                                                  ERDA
      NO. OF PUTURE YEARS TENTATIVELY
      ASSURED BEYOND CURRENT F.Y.
                                                          STARTING DATE
                                                            June  1977
'Funds approximate not for citation.<** -
                                                  52

-------
                  U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                           Form Approved
                                                                          OMB No.  158-R0081
                                              PROJECT NO. (Do rat use thl, ipace.1

                                              5SIE
                                                                 EPA-IAG-D6-E771-BEL
     Beatera Energy - Belated Overhead Monitoring  (WStCH)
   GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIOATOHS OR PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
     HASA ProJ. Coord. - H. Steaey, HASA B* - tu-i.«-tt>~,  DC 20546 - 8-755-8584
     HASA ProJ. Dir. - I.L. niton, XXZ - Earth Kesoorcss Lab - 1010 Cause Blvd - Slidell
        LA -  70548 - 8-685-6511
     HASA Prin. Investigator - Dr. A.T. Joyce-Earth jteseurces Lab (Address above) 685-6531
     HAgA T«w^.. Ttr»»««-4».t-Mp - J.». t,iA«-,*»o-g.i-«-».  V-mm***..* t^K t^^TV\f •Wya) 685-6531
   NAME AND ADDRESS OF APPLICANT INI	
                            ' INSTITUTION
   SUMMARY OF PROPOSED WORK -  (1) Objective., (2) Approach. (3) Current Plan, and/or Progress (200 words or less. Omit confidential data).
      In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
   porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.

     Obieetiv
     Th* obj active of this project 1» to transfer reaote sensor data acquisition and pre-
                         £ ran 1USA to KRA for «ni..Tjy-r*latai o««rbM.d •oaltorlag •7*t*-*u
     Approach
     tb* project will b« condBCtad la 3 phatMc wttfa data fro* •oleetcd altat. la
     U.S.  Of that total effort expended daring the project, approximately 50Z will be
     dedicated to the .nGitorlas of coal atrip adaa rahabllltatloo activltiae.
     the «arlrotH.*atal lapeet of mlaa month foa«U fuel pomr plant  eaiMleB.. frill accooat
     for approxtutely 301 of the total effort.   SehabllltatloB probleM aaaoelatad with
     oil ahale aztractlon will co.«prtM aboot 15-202 of the project  work.  Minor effort
     will  iocltada .waitorlag t*chal
-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        Farm Approved
                                                                       OMB No.  118-R0081
                                                              PROJECT NO. (Da ml u.e Uii>

                                                              SSIE
                                               IEPA	
                                                EPA-IAG-D6-E771SSU
TITLE OF PROJECT
Energy  Related Remote  and In Situ Sensing  Instrument Development
GIVE NAMES. DEPARTMENTS. AMD OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AHO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Dr.  6.  B.  Northam (804-827-2576), Atmospheric Environmental  and Sciences  Division
Dr.  F.  Allario (804-827-2986), Atmospheric Environmental and Science Division
Dr.  6.  L.  Gregory (804-827-2486), Marine  and  Applications Technology Division
NAME AND ADDRESS OF APPLICANT INSTITUTION
 National  Aeronautics  and Space Administration
 Langley Research Center
 Hampton.  VA  23665 _
SUMMARY OF PROPOSED WORK - (I) Objective.. (2) Approach. (3) Cwrem PUn> .ad/or PrO(n» (200 word! or leu. Omit 
-------
             U.S. ENVIRONMENTAL PROTECTION AGENCY
              NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
 'ITLE OF PROJECT
                                                               Form Approved
                                                             OMB No. 1S8-R0081
                                                      PROJECT NO. (Da not uae this specej

                                                      5SIE
                                                      EPA-IAG-D6-E684-BCK
Duality Assurance and Instrumentation in  Air § Water Pollution Monitoring
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
H. Okabe
Physical  Chemistry  Division
NAME AND ADDRESS OF APPLICANT INSTITUTION

National  Bureau of  Standards
Washington, DC  20234
SUMMARY OF PROPOSED WORK - (I) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or lesa. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes,
ABSTRACT
The quenching constants of S02  fluorescence excited  by a 216 nm  deuterium
source  have been, obtained for N2,  02 air  and C02 .  They are 0.75 ^ 0.09,
2.68 +  0.09, 1.16  +_ 0.01 and 0.74  + 0.07  respectively all in units 10'3
torr'T.   The fluorescence sinal of" S0        md stack emi       i
                     _
          The fluorescence  signal of"  S02 in simulated stack  emission in
several percent  lower than that in pure N2-  The  presence of NO does
not  interfere with the S02 measurement  by a fluorescence method.

INTRODUCTION
Fluorescence  in  the near ultraviolet has been observed when  S02 is irradi-
ated with the  Zn 213.8 nm  line.  Because the lifetime of the fluorescence
is  so short,  the quenching by air even  at one atmosphere is  still not
appreciable.   This forms the  basis of the measurement of low S02 concentra
tions in air.  For the application of this method to monitoring S02 in
source emission  such as stack gas and automobile  exhaust, one must
consider that  the composition of the emission gas is very different from
that of air.   Since different gases would be expected to show different
quenching properties for the  S02 fluorescence,  the signal would depend on
the composition  of the gas mixture.  The previous work was performed only
for S02-air mixtures.  In  this report the quenching constants of N2, 02,
and C02, the main constituents in stack emission  and automobile exhaust,
are obtained.  The S02 fluorescence signals are measured in  various ^-62
and N2-C02 mixtures at atmospheric pressure.  The effect of  NO ultraviolet
fluorescence  is  also investigated.            ("continued!
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
 dental, etc.)
                                   SIGNATURE OF PRINCIPAL INVESTIGATOR
                                 FOR OFFICE USE ONLY
   SUPPORT METHOD fCfiecft <
    AGENCY STAFF (7r,f rarmira/J
 FUNDS OBLIGATED
             F.Y.

             76
                        TASK NO.


                            1
                                         PROJECT OFFICER
                                         Jerry R.  McNesby
                                         RESPONSIBLE ORGANIZATION
                                         NBS
                   NO. OF FUTURE YEARS TENTAT1V
                   ASSURED SEYONO CURRENT F.Y,
                                                STARTING DATE
                                                                 ESTIMATED COMPLETION
                                                                  6/76
 EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND S1-S1E 76A WHICH MAY NOT BE USED.
                                       55

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                 H.  Okabe (continued)
CONCLUSION

It may be concluded that the S02 signal  in simulated stack gas  mixture is
about 5% lower than that of S02 in pure  N£ and about 101  higher than that
of S02 in air in the absence of water.   The presence of 1200 ppm NO shows
almost no effect on the S02 signal because of the  strong  quenching effect
of NO fluorescence by C02.   The results  are based  on a light source with a
peak at 216 nm and a half width of 23  nm.   Thus the  quenching effects of
stack gases may not be significant if  the  S02-N2 mixture  is used as a
calibration gas, in view of other factors  to be considered in the actual
measurement such as inhomogeneity in mixing and the  adsorption  of S02 on
the walls.  However if S02  is excited  by a source  emitting longer wave-
lengths, the quenching effects may become  significant.
                                56

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             U.S. ENVIRONMENTAL PROTECTION AGENCY
              NOTICE OF RESEARCH PROJECT
                                                              Form Approved
                                                             OMB No. 158-R0081
                                                      PROJECT NO. (Do r

                                                      5SIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                       EPA-IAG-D6-E684-SCK
 ITLE OF PROJECT
 Quality Assurance and  Instrumentation in Air  § Water Pollution Monitoring
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

I.  D. Deslattes
Dptical Physics Division
NAME AND ADDRESS OF APPLICANT INSTITUTION

 National  Bureau of  Standards
 Washington,  DC  20234
SUMMARY OF PROPOSED WORK - (1) Objective*, (2) Approach. (3) Current Plan, and/or Progress (200 words or less. Omit confidential data).
  In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to Investigators who request such information. Your summary is to be used for these purposes.
The  SO?  Fluorescence Project  to study the  feasibility  of using  laser
induced  fluorescence from 502 as  a pollution monitor has been completed.
The  following paragraphs summarize the  status of- the work on the spectro-
scopy of S02, lifetimes of  SC>2 and the  detection of  S02-

The  spectroscopy  of S02 was primarily done by Harry  J.  Dewey.   More than
20 vibronic bands  are located in the region of 234.8 nm (0,0,0)  to 218.6
nm.   He  was successful in assigning the  first 10 bands  through  224.7 nm
with independent  confirmation of the assignments by  J.C.  Brand  (University
of Western Ontario).  Band  assignments  at  higher energies  are made extreme
ly difficult due  to strong  coupling between the symmetric  and asymmetric
stretch  modes (vj  and vs) of  S02-  As a  result most  bands  consist  of an
admixture  of modes  rather than pure states.   The fluorescence spectra not
only permitted  the  above assignments but also determined the optimum
wavelengths for monitoring  the S02 fluorescence in detectors.

In order to measure the lifetimes and quenching rates  of S02 the Laser
Chemistry  Program acquired  a  fast dual  channel boxcar  with nanosecond
resolution.  The  boxcar is  scanned by a  signal averager and decay  curves
were stored for later computer analysis.   The combination of the short
laser pulse (typically 3-4  nsec), fast photomultiplier and boxcar  allow
determination of  lifetimes  down to 10 nanoseconds.   Published data of
quantum  yields  and  doubling  efficiency  suggested that  the investigations
be centered on  the  218,6 nm to 223.8 nm  region of

(continued)
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
 dental, etc.)
                                   SIGNATURE OF PRINCIPAL INVESTIGATOR
                                 FOR OFFICE USE ONLY
   SUPPORT METHOD (Check one)
 X  AGENCY STAFF flntramurat)
                        TASK NO.

                           la&2a
                          PROJECT OFFICER
                           J.R. McNesbv
                                         RESPONSIBLE ORGANIZATION
                                          Office of Air&Watar Manag., NBS
 FUNDS OBLIGATED
 la- 0
  2a-50K
76
                                                STARTING DATE
                                                                 ESTIMATED COMPLETION
                                                                 DATE
 EPA Form 5760-1 (7-72)    REPLACES PMS FORM 166 AND SI-SIE 7SA WHICH MAY NOT BE.USEO.
                                      57

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              R.  D.  Deslattes (continued)
In conclusion of this report some suggestions for possible future work
can be made.  To demonstrate the ultimate accuracy and detectability
obtainable with a laser induced fluorescence S02 monitor,  the above
suggestions for increasing the detectability should be carried out with
a flowing sample system similar to the one used in calibrating the NBS
S02 monitor.  It would also be advisable  to repeat the work with NO as an
NO monitor may also be possible with this technique.  Ultimately a
detector would utilize a flashlamp pumped dye laser-double system as time
resolution would not be a problem and significantly more photons could be
obtained to increase detectability limits.
                                  58

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                Form Approved
                                                               OjMS No. HS-ROOS1
                                   PROJECT NO, (Da not use this space)

                                   SSIE
                                                        EPA-IAG-D6-E684-BCK
  Quality  Assurance  and Instrumentation in  Air § Water  Pollution Monitoring
  StVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
  PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

  D. B.  Kittelson
  University of Minnesota
  NAME AND ADDRESS OF APPLICANT INSTITUTION
  Office  of Air and Water Measurement
  National  Bureau of  Standards
  Washington, DC  20234	
  SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
    In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
  porting research and are forwarded to investigators ftto request such information. Your summary is to be used for these purposes.

  OBJECTIVE
  The primary objective of this  program is  to develop  and characterize a
  continuous particulate sulfur  analyzer  for field use.   The analyzer is to
  be designed so that it may reliably and continuously measure sulfur
  aerosols  at concentration levels as low as encountered under clean ambient
  conditions (1 yg m~3) and still be usable at the much  higher concentratioi
  levels  encountered at emission sources.   A secondary objective  of  this
  program is to begin work on  a  laboratory  version of  the instrument which
  will be capable of identifying individual sulfur compounds in atmospheric
  aerosols.

  These  objectives are being pursued through a cooperative program between
  the University of  Minnesota  Particle Technology Laboratory and  the
  National  Bureau of Standards.

  Approach
  The  original instrument concept was envisioned to consist of an  aerosol
  collection system,  an aerosol  evaporation system, and a gas phase  flame
  photometric sulfur  detection system.  The collection  system was  to consist
  either of an electrostatic precipitation, impaction,  or filtration device
  which  would collect aerosol during an appropriate interval.  The collecte<
  aerosol would then  be evaporated/thermally decomposed and introduced into
  a gas  stream flowing to a flame photometric total sulfur detector.  The
  resulting signal  would be integrated and converted  to a total  sulfur
                                         URE OF PRINCIPAL INVESTIGATOR
                                  FOR OFFICE USE ONLY
    SUPPORT METHOD ,'Check one)
          STAFF (Intramural)
Funds Estimate'*'F-Y-
 [$75,000       76
                                          PROJECT OFFICER
                                           Jerry R.  McNeaby
                                          RESPONSIBLE ORGANIZATION
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                                          J8S§_
                                                  STARTING DATE
ESTIMATED COMPLETION
DATE
                                                  6/78
      approximate not for Citation. 56 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                       59

-------
2  D.  B.  Kittelson (^continued)
FUTURE WORK

The basic instrument concept has been established as sound.   The major
problem area in the current system is the flame photometric  detector.
Considerable effort will be directed toward shortening the time constant
of the instrument and increasing its sensitivity for this application.
Its response to a variety of sulfur and non-sulfur aerosols  will be
investigated in detail.

At the same time work on detailed characterization on the combined precip-
itator-flame photometric detector will continue.  Sensitivity to a
variety of aerosols will be measured, and possible interferences from
sulfur and non-sulfur gases, including water vapor, will be  studied.

Field tests will be performed in St. Louis this summer and in Los Angeles
this fall to determine the response of the instrument to actual atmo-
spheric aerosols .

The last phase of the work will consist of designing and building a com-
plete instrument package for field use.  A dichotomous sampler may be
fitted to the inlet to allow contributions from submicron and supermicron
particles to be established independently.

Testing of the heated inlet system for thermal speciation of the sulfur
aerosols is about to begin.  This work will continue with an ultimate
goal of developing a fast response thermal speciation device to connect
to the inlet of total sulfur aerosol detection.

Further work with the aerosol chromatograph will include testing of the
humidity response of a number of common atmospheric aerosol  constituents,
as well as field tests with actual atmospheric aerosols.
                                 60

-------
                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                  Form Approved
                                                                OMB No. 158-R0081
                                       PROJECT NO. (Do not use 6 AND S|-S|E 7SA WHICH MAY NOT BE USED.
                                          61

-------
          S. P. Wasik (continued)
In the second method, the total hydrocarbon concentration in the head-
space is measured as a function of volume of hydrogen bubbled through the
cell in order to obtain a "finger print" of the petroleum.  This method
takes advantage of the fact that the total hydrocarbon concentration
depends only on the concentrations of each individual hydrocarbon and
its partition coefficient.

The hydrogen head-space is fed directly into a hydrogen flame detector.
The detector signal is plotted against the hydrogen volume.

The third method is concerned with comparing the fluorescence spectra of
an aqueous extract of petroleum before and after extraction with electro-
lylically generated hydrogen.  Since the fluorescence compounds in the
water extract have different partition coefficients their concentrations
and hence their spectra will be changed by the extracting process.

A fluorescence cell was modified to an electrolytic hydrogen extraction
cell by the addition of a gold electrode at the base of the cell and
electrode-salt bridge near the top of the cell.  This cell was contained
in a constant temperature bath located in the optical bath of a fluores-
cence spectrometer.  The fluorescence spectrum of the water extract was
measured prior to and after hydrogen extraction.

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                 Form Approved
                                                                OMB No. H8-R0081
                                    'HOJECT NO. fDo not use Ihia space)

                                   SSIE
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                    EPA-IAG-D6-E684-BCL.BCM
   juality Assurance and  Instrumentation in Air § Water  Pollution Monitoring
   GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   D.  A. Becker
   Acting Program Manager
   Recycled  Oil, IMR
   NAME AND ADDRESS OF APPLICANT INSTITUTION

   National Bureau of Standards
   Washington, DC   20234
   SUMMARY OF PROPOSED WORK - (1) Objective.. (3) Approach, (3) Current Plans and/or Progress (.200 word, or lea.. Omit confidential data).
     In the Smithsonian Science Information Exchange, summaries of work In progreas are exchanged with government and private agencies sup-
   porting research and are forwarded to inveatigatorf.«ho request such information. Your summary is to be used for these purposes.

   ABSTRACT
   In cooperation with the Environmental  Protection  Agency  (EPA)  and other
   Government agencies,  the National Bureau of Standards (NBS)  is developing
   methodology and Standard Materials for measuring  the environmental effects
   resulting from increased energy production.  The  NBS Analytical Chemistry
   Division is initiating research and development in the areas  of Reference
   Materials, instrumentation,  and methods required  for monitoring air and
   water  quality associated with energy production.

   OBJECTIVE
   The research and  development  leading  to Reference  Materials,  instrumenta-
   tion and methods  urgently needed for  the monitoring of air  and water qual
   ity associated with increased energy  development of many different types.

   MOTIVATION
   Due to  the current and future energy problems facing the U.S., it has
   become  imperative  for the  rapid development of  the internal  energy capa-
   bilities of this country.   In order to maintain an acceptable level of
   environmental pollution, the methods devised for increased utilization of
   these  internal  energy sources (e.g. petroleum,  coal, uranium, geothermal)
   must be adequately evaluated and monitored for  effects on air and water
   pollution.  In  order to effectively carry out its responsibilities in
   (continued)
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED CMedical,
   dental, etc.)
                                      SIGNATURE OF PRINCIPAL INVESTIGATOR
                                    FOR OFFICE USE ONLY
     SUPPORT METHOD (Check one)
      AGENCY STAFF (IntrdmuraV
      w-i
      BCM-l
 Funds Estimate **TT
  ---$4i5,aoqF7v
      -$300,000|
                                            'ROJECT OFFICER
                                            Jerry  R.  McNesby
                                           RESPONSIBLE ORGANIZATION

                                            NBS
NO. OF FUTURE YEARS TENTATJV
ASSURED BEYOND CURRENT F.Y.
                              STARTING DATE
                                              BCL-6/79.BCM-l/
'Tunds approximate not for Citation' 'ss AND SI-SIE 7SA WHICH MAY NOT BE USED.
                                        63

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       D.  A.  Becker (continued)
these areas, the EPA has requested the assistance of the NBS Analytical
Chemistry Division for research and development of Standard Reference
Materials.

APPROACH

The overall approach to be taken involves three (3) basic steps.  First,
in areas of well-defined pollution effects the emphasis will be on the
development and Certification of Standard Reference Materials (SRM's) to
enable effective quantitation.  Examples of such well defined pollution
effects include gases in air pollution (e.g., sulfur dioxide, carbon
monoxide) and trace metals in water pollution (e.g., mercury, arsenic,
lead).  Second, in areas of known effects but imperfect measurement
methodology, research and development on analytical methods and instrumen-
tation will be undertaken.  Examples of these areas include particulates
and trace organics in air and water pollution.  Third, in areas of new or
increased energy production techniques (i.e., coal gasification and lique-
faction, uranium production, etc.) a series of workshops will be held to
help define the current state-of-the-art, and future requirements for
analytical Reference Materials and methodology for air and water pollution
measurements.

PROGRESS

Appropriate Interagency Agreements became effective on May 25, 1975.
Projects have been initiated.

PLANS

In fiscal year 1976, the three (3) research and development areas described
under Approach, above, will be initiated.  A number of SRM's will be pro-
duced and Certified.  Investigations into the relevant raw materials,
products and residues from the various energy systems will be made.  A
series of Workshops on the energy production processes and their pollu-
tion potential will be held to determine SRM's required.
                                 64

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                  Form Approved
                                                                 OMB No. J58-R008J
                                         PROJECT NO. (Da ,

                                         SSIE
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                         TPA	
                                         EPA-IAG-D6-E684-BCN
   Quality  Assurance and Instrumentation in Air g Water  Pollution Monitoring
   GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
    J.  M. R.  Hutchinson
    Applied Radiation  Division
   NAME AND ADDRESS OF APPLICANT INSTITUTION

   National Bureau of Standards
   Washington, DC   20234
   SUMMARY OF PROPOSED WORK - (1) Objective!, (J) Approach, (3» Current Pl«n» and/or Progress (200 word, or less. Omit confidential data).
     In the Smithsonian Science Information Exchange, aummariea of work in programs are exchanged with government and private agencies sup-
   porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.
    The project is aimed at providing traceability -measurements through the
    Environmental Protection Agency at  Las Vegas  CEPA-LV) of  certain  radio-
    nuclides  not covered under  existing programs.   These radionuclides  were
    chosen because they are released as environmental pollutants from nuclear
    power reactors  (such as light water reactors  and fast-breeder  reactors),
    coal burning power plants  and, or other sources.

    ESTABLISH LABORATORY FACI1ITY

    Ci)   The glove boxes have  been installed and the modifications to  the
          radiochemistry laboratory are now complete.  The electronic equip-
          ment associated with  the radon  counting system has  been  almost
          totally replaced and  tested.

    Cii)  Plans for  the layout  of the  "medium geometry" counter have  been
          completed.   The counter and the associated electronics are  being
          assembled.

    2J°Po STANDARD

    Forty polonium-210 test solutions were prepared, calibrated, and  sent to
    EPA-LV.   Reports  of Calibration have  been furnished.

    The mixed gamma-ray standard has been furnished to EPA-LV as described in
    the previous progress report.

    (continued)      	
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,  SIGNATURE OF PRINCIPAL INVESTIGATOR
   dental, etc.)
                                    FOR OFFICE USE ONLY
      SUPPORT METHOD (Check one)
                                            PROJECT OFFICER
                                            Jerry  R.  McNesby
                                            RESPONSIBLE ORGANIZATION
                                            NBS
Funds Estimate^
  |$51,000
76
     NO. OF FUTURE YEARS TENTATIVELY
     ASSURED BEYOND CURRENT F.Y.
                                                    STARTING DATE
                                                                     ESTIMATED COMPLETION
DATE
12/79
Funds approximate not for citation."166 AND S'-SIE 76A WHICH MAY NOT SE USED-
                                         65

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             J. M. R.  Hutchinson (continued)
The 22SRa-in-soil standard is being prepared from Moncos shale, which was
ground, milled, blended and sieved by EPA-LV.  Homogeneity tests have been
conducted on lOg and lOOg samples, and the results show no need for
further homogenizing.   Five lOg samples were radiochemically analyzed for
226Ra using a fusion technique and ionization chamber counting of the
222Rn.  The results agree with corroborative measurements on emitted y
rays using a Ge(Li) detector, and known y-ray abundances.

Plans are nearly complete for the 239Pu standards and production will
begin within the next  two months.
                                  66

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                           Form
                                                                         OMB No. 1S8-R0081
                                                 PROJECT NO. (Do no* use thit *pace>
                                                 SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                TPA	

                                                 EPA-IAG-TK-E693-HIW
    : OF PROJECT

   UNDERWAY T-TATFR SAMPT.TOr, SYSTEM
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   Charles  D.  Kearse
   Deputy Director, Engineering Development  Laboratory
   NOAA/NOS/C61
   Rockville,  Maryland
NAME AND ADDRESS OF APPLICANT INSTITUTION

   NOAA, Rockville, Maryland 20852
SUMMARY OF PROPOSED WORK - (I) Objective. (2) Approach. (3) Currant Plan! and/or Progress (200 words or !«»». Omit confidential data).
   In the Smithsonian Science [niurnuition Exchange, summaries of work in progress arc exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such Information. Your sumoiary It to be used for these purposes.
  (1)   Objective

       The objective of  this program is to  develop a cost  effective shipbome
  system with which to measure  those physical and chemical parameters which determine
  the identity, concentration,  transport, and distribution of pollutants arising  from
  energy activities in  the marine  environment.

  (2)   Approach

       An  underway, interactive water measurement system that will obtain continuous
  water samples and oceanographic  measurements will be developed.  The  major  elements
  of the development program consists of:

             a.   The Current/Depth  Measurement Subsystem
             b.   The Water Sampling and Measurement Subsystem
             c.   The Data Processing, Display and Navigation Subsystem
             d.   System  Integration, Test and Techniques  Development.

  (3)  Current  Plans and Progress

       An  application study is  currently in progress to  define the requirements in
  progress to define the requirements for water sampling and on-board chemical
  analysis techniques.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED r.V
cfi-nr.ll. »-fo.)
              N/A
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD fC
  NDiCBLIGATED

  ?U5K
76
                                                 PROJECT OFFICER
                                                   John
                                 	           Jr.
                                 RESPONSIBLE ORGANIZATION

                                    SOAA/NOS/EDL/C61
       NO OF FUTURE YEARS TENTATIVELY
       ASSUPtD 9EYOND CURRENT F.Y.
STARTING DATE

August  1975
ESTIMATED COMPLETION
°ATEDece;nber 1979
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND Sl-SIE 7fi6^MiCM MAY NOT BE USED.
                                             67

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                        OMB No. 158-R008/
                                                               PROJECT NO. (Do not u«0 thlt

                                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                    EPA - IAG - D6 -E693  - BUI
TITLE OF PROJECT
          Ocean Oil  Spill Concentration and Trajectory Forecast
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
          Celso. S.  Barrientos, Research Meteorologist
          Kurt W. Hess,  Physical  Scientist
          David M. Feit,  Research Meteorologist
          W427, NOAA-NWS/TDL, Silver Spring, Md.   20910
NAME AND ADDRESS OF APPLICANT INSTITUTION

          NOAA, Rockville,  Md.  20852
NUMMARY OF PROPOSED WORK - (I) Objective*. (2) Approach. (3) Current Plan* and/or Progress (200 word* or !•«». Omit conTldantlal data).
   In the- Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government arid private ag«ncle» aup-
Torting research and are forwarded to investigators who request such information. Your summary is to be ua«d for these purpose*.
   The  objective of  this program is  to develop a numerical  model which will predict
    the  movement and  concentration  of spilled oil in the oceans as a function of
   space and time.  The  program  also includes  provisions for  forecasting current,
   wind,  and wave fields that have not previously been available.

   To accomplish this objective, the program is  divided into  seven tasks:  (1) Surface
   wind field, (2) Ocean currents,  (3)  Direct  wind drag effects,  (4) Wave  transport,
    (5)  Sea-Air pollutant transfer,  (6)  Horizontal turbulent diffusion, and (7)  Modal
   integration.  Tasks (1) and  (7) are done in-house and the  rest of the work is to
   be done by contract.   The final result of the project will be an operational oil
   spill trajectory  forecast program.

   Considerable progress has been  made on the  surface wind  task.   A contract was
   awarded and two additional contracts will soon be awarded.   We have coordinated
   with related projects within  NOAA and other agencies.  Planning and model inte-
   gration is in progress.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Mvilic.'t.
                   NA
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR

                                         Celso S.  Barrientos
                                                             DATE

                                                             23 Sept. 1976
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD (Cli,-ck <
                                 1-7
                                                PROJECT OFFICER
                                                John W. Townsend, Jr.
                                                RESPONSIBLE ORGAN1 ZATION
                                                NOAA/NWS/TDL  U427
   $150
    STB
 76
76TO
                      ASSURED BEYOND CURRENT F.Y.
STARTING DATE
July 1975
                                                             ESTIMATED COMPLETION
                                                             "See.  1979
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT 8E USED,
                                               68

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                           Form Approved
                                                                         OMB No. D8-R0081
                                                PROJECT NO. fDo not ua« «./«

                                                SSIE
                                                                 EPA-IAG-D6-E693-BDZ
 Shipboard Environmental Data  Acquisition  System  (SEAS)
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Richard  R.  Reynolds, Project Manager"
 Equipment Development Laboratory, Systems Development Office
 I'lational  Heather  Service, 8060 13th  Street
 Silver Spring, Maryland  20910
NAME AND ADDRESS OF APPLICANT INSTITUTION

 NOAA,  Rockville,  Maryland   20852
SUMMARY OF PROPOSED WORK -  (I) Objective. (2> Approach, (3) Current plug and/or Progress (200 word, or [ess.  Omit confidential data).
   In Ihe Smithsonian Science Intermit Ion Exchange, summaries of work in progress are exchanged with government and private agenciea sup-
porting research and are forwarded to investigator* who request such information. Your summary !• to be used for theae purposes.

 1.  Objective^  The SEAS  program objective is to  develop an automated meteorological/
     oceanographic observation system for use on board ships.

 2.  Approach:   (a)  Develop an engineering model  SEAS and  test  it in an  operational
                       environment.

                  (b)  Develop an automated expendable bathythermograph (XBT)
                       capability as  an add-on sensor  to the  SEAS  system.

                  (c)  Prepare prototype  model SEAS  specifications and procure
                       five  systems for testing on different  classes of ships.

 3.  Current Plans/Progress:  The engineering model  (SEAS-1; has been developed
     and is  currently  undergoing tests  and evaluation on the NOAA Ship RESEARCHER.
     The automated XBT system will  be completed  by early CY 1977 and integrated
     with SEAS-1  for testing.  Prototype model  specifications  will be developed
     in FY 1977.
 3ENTIFY PROFESSIONAL SCHOOL IN VOL VED (Metlffal,
      .-re.)
                                        FOR OFFtCE USE ONLY
    SUPPORT METHOD (Chirk t
               'Hianmural)
                                  1-5
                                 PROJECT OFFICER
                                 Roy S.  Wyett
                                 HE5PONSI3LE ORGANIZATION
                                 NOAA
      OBLIGATED
      $20K
      580K
F.Y.
 76
 76
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
STARTING DATE

    July 1975
                                                          Dec.  1977
• EPA Form 5760-1 (7-72)  •  REPLACES PHS FORM 16S AND SI-SIE 76A WHICH MAY NOT BE USED.
                                             69

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approvttt
                                                                       OMB No.  US-ROOSI
                                                               PROJECT NO. (Do not use Into

                                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                EPA-IAG-D6-E693-BEA
riTLE OF PROJECT
      Standardization and Intercalibration techniques for Marine Monitoring
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

      Michael Basileo,  Chief,  Metrology Branch
      NOAA-NOS,  Office of Marine Technology, Test and Evaluation Laboratory
      Bldg 160  - Navy Yard Annex
      Rockville,  Maryland 20852
NAME AND ADDRESS OF APPLICANT INSTITUTION
      NOAA,  Rockv-me,  Md.   20852
SUMMARY OF PROPOSED WORK - (1) Objective*. (2) Approach. (3) Currant Plans and/or Progress (200 word* or less. Omit confidential data).
   In the- Smithsonian Sc-ience Information Exchange, summaries of work in progreaa are exchanged with government and private agencies •up-
porting reseurch and are forwarded lo investigators who request such information. Your summary 1* to be used for theaa purpose*.

           The objective of this project is  to  develop common techniques for the
      standardization and intercalibration of sampling and analytical methodologies
      in the marine  environment.   Effort  will  be concentrated  on developing
      appropriate mechanisms for coordination of standardization and intercalibra-
      tion activities among state,  local,  and private agencies.

           In support of this objective, contracts have been awarded for the develop-
      ment of a dissolved oxygen laboratory  standard and a dynamic test standard for
      current meters;  a transfer standard for interlaboratory calibrations has been
      procured; and  an investigation into the traceability of in-situ water  quality
      measurements compared to  existing chemical standards has begun.

           Current plans include the development of a users' guide for optical
      instrumentation; an evaluation of quality of data obtained from water  quality
      "test kits"; a comparison study of water  analysis methods  utilized for seawater
      in reference to standard  techniques  developed for fresh water;  and establish-
      ment of an  interlaboratory calibration capability for precision pressure
      sensors.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (
      N/A
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                          Michael
                  9/24/76
                                      FOR OFFICE USE ONLY
                                1-3
                                               PROJECT OFFICER
                                                John Ht  Townsend. Jr.
                                               RESPONSIBLE ORGANIZATION
                                                NOAA
FUNDS OBLIGATED
     S25Q  K
                76
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED 3EYONO CURRENT F.Y.
                         1
                                                        STARTING DATE
7/75
ESTIMATED COMPLETION
DATE

   12/79
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                          70

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        Form Approved
                                                                      OVfl No. ISa-ROOSl
                                               PROJECT NO. rOo nor use this

                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                              EPA-IAG-D6-E693-BEB
                Lidar Techniques for Measuring Particulate  Pollutants from Energy
                Production arid Their Transport and Dispersion  Processes.
GIVE NAMES. DEPARTMENTS. ANO OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
                V. E.  Derr (principal  investigator), Supervisory Physicist
                R. L.  Schwiesow  (co-investigator), Physicist
                G. T.  McNice, Physicist         M. J. Post, Electronic Engineer
                N. L.  Abshire, Physicist        R. E. Cupp, Physicist
                G. M.  Lerfald. Physicist	R. F. Calfee.  Physicist	
NAME AND ADDRESS OF APPLICANT INSTITUTION
                                    Wave Propagation Laboratory
                                    Atmospheric Spectroscopy  Program Area, R45x3
                                    Environmental Research  Laboratories, NOAA
                                    Boulder. Colorado 80302	
SUMMARY OF PROPOSED WORK - (1) Objectives.  Approach, (3) Current PUns and/or Progress (200 wards or leal. Omit confidential data).
  In the Smithsonian Science Information Exchange, summaries of work In progress are exchanged with goverrucBnt and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.
 (1)  Objectives (two tasks):
 a)    Develop and  verify economical  lidar measurement techniques  for remote tracing and
   analyzing of pollutants arising from power plants.
 b)    Develop and  test an operational, infrared, continuous-wave  Doppler lidar sensor
   for high resolution measurements  of atmospheric wind,  turbulence, and aerosol back-
   scatter aspects of pollutant transport.

 (2)  Approach:
 a)    Vi'e are extending the capabilities of the existing pulsed lidar to include polari-
   zation sensitivity and multiwavelength operation.  This  equipment is being used  in
   field experiments at Colstrip, Montana and in various  Colorado locations to test the
   plume characterisation capability of the lidar.  Experimental  developments are guided
   by theoretical  studies on aerosol backscatter properties.
 b)    The WPL mobile Doppler lidar system is being applied  to  wind profile measurements
   in various environments and to the velocity structure  of natural atmospheric vortices
   Equipment modifications are underway to  improve the  lidar capability in stack emissicr
   measurements, three-component  wind profiles, and large-diameter aerosol profiles.

 (3)  Progress:
 a)    Lidar backscatter data on intensity and polarization  from various natural and man-
   made atmospheric particles has been obtained in three  different locations.  Depolar-
   ization is a significant aerosol  identifier.  Theoretical calculations are underway.
 b)    Doppler lidar 1-component wind profile measurements have been completed in desert,
   seacoast and urban environments.   Preliminary velocity data is available on cooling
   tower plumes and power plant stack-effluents.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (M.-tltcnl,
(frtir.tf. crr.>
         N/A
                                          V. E. Derr, PA Chief7~R45x3
                                                            DATE

                                                            Oct.  1,  1976
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD [On-.-k IKII-)
FUNDS OBLIGATED
 195
  50
76
76TQ
                            TASK NO.

                                1&2
                                PROJECT OFFICER
                                   John W. Tov/nsend,  Jr.
                                               RESPONSIBLE ORGANIZATION
                                                   NOAA
       NO. Of FUTURE YEARS TENTATIVELY
       ASSURED sevoNO CURRENT F.Y. -
STARTING DATE
July 1975
ESTIMATED COMPLETION
        1930
EPA Form 57oO-t (7-72)    REPLACES PH5 FORM 1SS ANO SI-SIE 76A WHICH MAY NOT 3E USED.
                                          71

-------
                  U.S. ENVIRONMENTAL PROTECTION AGENCY
                    NOTICE OF RESEARCH PROJECT
                                                                                 Form Approved
                                                                               OMB No.  H8-KOOS1
                                                                      PROJECT NO. (Da „„( „„ ihlm

                                                                      SSIE
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                 EPA	

                                                   EPA-IAG-D6-E693-BEK
    i'fuE^bF PROJECT       ""'"""""'"          _.....--.... ....
    Air Quality and Surface  Wind  Monitoring in  Montana
   GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER

   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
    Michael  D. Roach, Chief, Air  Quality Bureau
    M8X. Botz, Water Quality Bureau
    Benjamin Hake,  Administrator, Environmental  Sciences Division
   NAME AND ADDRESS OF APPLICANT INSTITUTION     .  .  _  .         ,.  .     - ,,   . _
    Department of  Healtn  and Environmental  Sciences,  State of Montana
    Soaswell  Building
    Helena,  Montana  59601
   SUMMARY OF PROPOSED WORK- (1) objectives, 
-------
                  U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
                                                                               Form Approved
                                                                             OMB No. IJ8-R008J
                                                 PROJECT NO. (Do not u,, Ihl, space)

                                                 SSIE
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                 EPA

                                                  EPA-IAG-D6-E693-BEK
    Collection of Upper Air  Data 1n  the Fort  Union Basin
  GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
    ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
    Dr. Ray  Booker
  NAME AND ADDRESS OF APPLICANT INSTITUTION
    Aeromet,  Inc.
    P.O. Box  FF
    Norman. Oklahoma
     73069
   SUMMARY OF PROPOSED WORK - (I) Objective., (2) Approach. (3) Current Plan, and/or Progress (200 word, or loss. Omit confidential data).
     In the Smithsonian Science Information Exchange, •ummariee of work in progress are exchanged with government and private agencies sup-
   porting research and are forwarded to Investigator* who request such information. Your suromarT is to be used for these purposes.

    This study Is a  continuation of a contract that  1s  providing upper air data  at
    seven  sites: Craig and  C-b 011  Shale Tract, Colorado; Hanksvllle  ana Escalante, Utah;
    Casper and Rock  Springs, Wyoming.  Temperature,  wind speed and direction versus
    altitude are being measured via pilot balloons  and  temperature sondes.  Pilot
    balloons are released twlce-a-day, every-other-day.  Temperature  and wind  data are
    used to generate stability-wind rose data  on a  seasonal, annual and monthly  basis.
    Summaries of Inversions and mixing-layer heights aee provided too.
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
   dental, ere.)
                                             SIGNATURE OF PRINCIPAL INVESTIGATOR
                                           FOR OFFICE USE ONLY
      SUPPORT METHOD (Check onej
Funds Estimate*
   515,714
76
                                TASK NO.


                                      1
                                 PROJECT OFFICER
                                  Mr,  Machta
                                                    RESPONSIBLE ORGANIZATION

                                                      NOAA
      NO. OF FUTURE YEARS TENTATIVELY
      ASSURED BEYOND CURRENT F.Y.
                                                              STARTING DATE
                                                                1975
ESTIMATED COMPLETION
DATE
                                                                 1977
 Funds  approximate  not for Citation, iss AND SI-SIE 76A WHICH MAY NOT BE USED.
                                              73

-------
                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PROJECT
 Utah Visibility Program
                                                                              Form Approved
                                                                            OMB No. DS-K0081
        PROJECT NO. (Do not uae tMa apa-ce)

        SSIE                   	
        EPA	
         EPA-IAG-D6-E693-BEK
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Dr. R.  F.  Peuschel
NAME AND ADDRESS OF APPLICANT INSTITUTION
 riOAA - Environmental Reserach  Laboratory
 Boulder,  Colorado
SUMMARY OF PROPOSED WORK - (1) Objective!, (2) Approach. (3) Current Plans and/or Progreas (200 word* or lees. Omit confidential data).
   In th« Smithsonian Science Information Exchange, summaries of work In progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for these purpose*.

Aii intensive  data collection  of parameters which may be related to  atmospheric
visibility will  be conducted  in the San Rafael  swell  area  in Central-eastern Utah.
Light  attentuatlon, particuiite concentrations, particle chemistry, gaseous pollutant
concentrations,  and wind  data will be obtained.  A  baseline program in addition to
the assessment of the  impact  of four  coal-fired power plants upon visibility will
be assessed.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
dental, etc.)
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
                                         FOR OFFICE USE ONLY
   SUPPORT METHOD fCneck one;
    AGENCY STAFF (Intramural)
                                                  PROJECT OFFICER
                                                  Mr. Machta
                                                  RESPONSIBLE ORGANIZATION
FUNDS OBLIGATED
                 76
                       NO. OF FUTURE YEARS TENTATIVELY
                       ASSURED BEYOND CURRENT F.Y.
[STARTING DATE
1975
                                                                                       1977
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 ANO SI-SIE 76A WHICH MAY NOT 9E USED.
                                               74

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                           Form Approved
                                                                         O.MS No. ISS-R0081
                                               PROJECT NO. tDo not u,, 
-------
                   U.S. ENVIRONMENTAL PROTECTION AGENCY
                    NOTICE OF RESEARCH PROJECT
         PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
   TITLE OF PROJECT
    Air Quality and Surface Wind Monitoring  1n Utah
                                                                                 Form Approved
                                                                               OMB No. 158-RQ081
                                                                      PROJECT NO. (Da not use this apac«)

                                                                      SSIE
                                                 EPA

                                                 EPA-IAG-D6-E693-BEK
   GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT,
    Alvin E. Rlckers,  Director
   NAME AND ADDRESS OF APPLICANT INSTITUTION
    Bureau of  Air Quality, Division  of Health, State of Utah
    44  Medical  Drive
    Salt Lake  City, Utah  84113     	
   SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plant and/or Progress (200 word* or less. Omit confidential data).
      In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
   porting research and are forwarded to investigators who request such information. Your summary la to be used for these purposes.

    The state will install  and operate air monitoring stations at: St.  George,  Eraers Co.,
    Vernal, Castle Dale, Ca1nev1lle,  Kanab, Escalante, Bullfrog,  Marina, and Wahweep
    Marina.

    These monitoring  stations  will  collect air data as background before power  plants  are
    built.
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
   denial, etc.)
                                               SIGNATURE OF PRINCIPAL INVESTIGATOR
      SUPPORT METHOD (Check one)
Funds Estimate*
  |$15, 714
76
                                            FOR OFFICE USE ONLY
                                                     PROJECT OFFICER
                                                     Mr. Machta
                                                     RESPONSIBLE ORGANIZATION

                                                      NOAA
                                                               STARTING DATE
                                             1975,
                                                                                           1977
       approximate not for Citation. '«« AND si-sie TSA WHICH MAY NOT BE USED.
                                                 76

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U.S. ENVIRONMENTAL PROTECTION AGENCY
NOTICE OF RESEARCH PROJECT
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
Form Approved
OMB No. 158-R0081
PROJECT NO. (Do not use till, apace;
SSIE
EPA-IAG-D6-E693-BEK
Air Quality and Surface Wind Monitoring In Wyomina
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Robert Sundin, Director, Oept of Environmental Quality
Randolph Wood, Administrator, Air Quality Division
F. Gerald Biickwell, A1r Quality Supervisor »
NAME AND ADDRESS OF APPLICANT INSTITUTION
Department of Environmental Quality
Hathaway Building
Cheyenne, Wyoming 82002
SUMMARY OF PROPOSED WORK - (1) Objectives. <2) Approach, (3) Current Plans and/or Pro en
In the Smithsonian Science Information Exchange, summaries ot work in progress are exchange
porting research and are forwarded to investigators who request such information. Your summary i
The objective of this project is to maintain and operate e
monitoring stations established at certain sites within tl
FY'76, there were seven sites and in FY'77, there wir* be
will be continuous monitoring sites. These stations or si
data in possible energy development aceas within Wyoming e
to assess possible deterioration of Wyoming's air from en«
•jtates. The sample operation will be conducted for apperi
as (200 words or less. Omit confidential data).
d with government and private agencies sup*
i network of ambient air
ie state of Wyoming. During
nine sites, three of which
tes will provide air quality
md will provide baseline data
.rgy development In surrounciin
od of 24 months.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medlcel, SIGNATURE OF PRINCIPAL INVESTIGATOR DATE
dental, etc.)
FOR OFFICE USE ONLY
SUPPORT METHOD (Check one)
X ASENCV STAFF (Intramural)
X NEGOTIATED CONTRACT
RESEARCH GRANT
unds Estimate* F-Y- XSSUH'E:
$15/714 76
TASK NO. PROJECT OFFICER
Mr. Machta


NOAA

UTURE YEARS TENTATIVELY STARTING DATE ESTIMATED COMPLETION
1975 1977
^FundS approximate not for citation. '« ANDSI-SIE 76A WHICH MAY NOT BE USED.
                                               77

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                           Form Approved
                                                                         OMB No.  H8-R0081
                                                                PROJECT NO. (Do not •»» thlt «p«c«J

                                                                SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                EPA-IAG-D6-E693-BEK
TITLE OF PROJECT
 Ait* Quality and Strtfact Wind Monitoring  in Horth Dakota	.	
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 W.  Van Heuvelen, Chief Environmental Health a Engineering Services
 Gene A. Christiansen,  Director,  Division of Environmental Engineering
 Dana Mount, Assistant  Director,  Division of Environmental Engineering
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Environmental Health  and Engineering Services
 .iorth Dakota State  Department  of Health,  State Capitol
 Bismarck,  North Daaoi*  5S505
SUMMARY OF PROPOSED WORK- (1) Objectives, (2) Approach, (3) Current Plan* and/or Progress (200 words or le«». Omit confidential data).
   In the Smithsonian Science Information Exchange, lumraaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such Information. Your summary La to be uaad for these purpose*.

 The objective of  this project is to maintain and  operate a  network of  eight ambient
 air monitoring stations established at certain sites  1n western  North  Dfckota.   These
 stations will provide air quality data in  possible  energy development  areas within
 siorth Oabata and  will provide baseline data to assess possible deterioration of Nortii
 Dakota's air from enargy development in  surrounding states.   The sampling operation
 will be conducted for a period of 24 months.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
dental, etc.)
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD (Check c
    AGENCY STAFF (Intramural)
                                                PROJECT OFFICER
                                                Mr. Machta
                                                RESPONSIBLE ORGANIZATION
                                                 NOAA
Funds Estimate •
     $15,714
                 76
                                                          STARTING DATE
1975
ESTIMATED COMPLETION
DATE
    1977
    approximate not for Citation; '66 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                           78

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                            Form Approved
                                                                          OMB No.  158-R0081
PROJECT WO. (Da not use this apace)

SSIE
                                                                   EPA-IAG-D6-E693-BEK
 Air Quality and  Surface  ..inj .Monitoring 1n  South Dakota
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OB PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Or. Allyn  Lockner,  Oept  of Environmental Protection
 Roger Stead, Oept  of Environmental  Protection
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Department of Environmental  Protection
 Joe Foss  Building
 Pierre, South Dakota  57501
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 word* or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries at work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.

 The objective  of  this project is to maintain and operate a network of three ambient
 air monitoring stations established at certain sites  within  the state of South  Dakota
 (Belle  Fourche, Buffalo,  and Lemmon).  These stations will provide dar quality  data
 in possible energy development araas within  South Dakota and will provide baseline
 data to assess possible deterioration of South Dakota's air  from energy development
 in surrounding states.  The sample operations will  be conducted for a period of
 24 months.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
                                        FOR OFFICE USE ONLY
   SUPPORT METHOD (Check one)
    AGENCY STAFF flntrarmtral)
Funds Estimate?1
    15, 714
                 76
                                                  PROJECT OFFICER
                                                  Mr. Machta
                                                  RESPONSIBLE ORGANIZATION
                                                   NOAA
                       NO. OF FUTURE YEARS TENTATIVELY
                       ASSURED BEYOND CURRENT F.Y.
                                                           STARTING DATE
                                                                1975
              ESTIMATED COMPLETION
              DATE
                 1977
     approximate not for Citation, se AND SI-SIE 7SA WHICH MAY NOT BE USED
                                         79

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Fu
*
Fu
U.S. ENVIRONMENTAL PROTECTION AGENCY
NOTICE OF RESEARCH PROJECT
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PROJECT
Air Quality and Surface Wind Monitoring in Colorado
Form Approved
OMB No. 118-R0081
PROJECT NO. (Do not u*e thla apace;
SSIE
EPA
EPA-IAG-D6-E693-BEK

GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT,
Mesa College, Grand Junction, Colorado
Wayne Max, Air Pollution Control Division
NAME AND ADDRESS OF APPLICANT INSTITUTION
Colorado Department of Health
4210 East llth Avenue
Denver, Colorado 80220
SUMMARY OF PROPOSED WORK - (1) objectives, (2) Approach, (3) Current Plan* and/or Progress (200 word* or less. Omit confidential data).
In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
Install and operate air monitoring sites in the energy areas of western Colorado to
collect baseline data prior to major expansion of energy activities. Particulate
samples from the energy area will be analyzed for nitrate and sulfate content.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical, SIGNATURE OF PRINCIPAL
dental, etc.)
FOR OFFICE USE ONLY
SUPPORT METHOD (Check one> TASK NO. PROJECT OFFICE
X AGENCY STAFF (Inltimuralt Mf . M3Ch
X NEGOTIATED CONTRACT 1 RES PONSI BL E OH
RESEARCH GRANT 1NVJAA
nds Estimate* F'Y' A?su°RFE£uaTEJYoENSEcAuRRSREENTTF YVELY STA
$15,714 76

INVESTIGATOR DATE

R
.a
GANIZAT1ON
RT1NG DATE ESTIMATED COMPLETION
DATE
1975 1977
9E USED.
80

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                           Form Approved
                                                                          OMB No. I58-R0081
      PROJECT NO. (Da not use ihi, apace)

      S5IE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                 EPA-IAG-D6-E693-BEK
  Collection of Upper A1r Data  at Gillette, Wyoming and Stanton, .North Dakota
SIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
  Donald Hadley  -  Project Supervisor
  Western Scientific Services,  Inc.
  328 A1r Park Drive, Fort Collins*. Colo.  8052]
NAME AND ADDRESS OF APPLICANT INSTITUTION
  Same as  above
SUMMARV OF PROPOSED WORK- (I) Objectives, (2) Approach, (3) Currant Plana and/or Progress (200 words or lea*. Omit confidential data).
 % In the Smittuonian Science Information Exchange, suramariee of work in progress are exchanged with government and private agencies tup-
porting research and are forwarded to Investigators who request such information. Your summary is to be used for these purposes,
       This study  1s a continuation  of  a 5  site data collection program Initiated in
  June of 1975.  Upper air  temperature  and  wind data was  collected and analyzed at
  the following areas:   Gillette, Wyo;  Bowman  4 Stanton,  H.D.; Colstrip 3
  Glendive, MT.  Data was collected  during  June 1975- May 1975.  This study  extends
  the data collection at Gillette &  Stanton for another year.
       Pilot  balloons and temperature soudes were released 2 times per day every
  other  day during the initial 12 month period and will continue in  this study once
  the contract 1s  finalized.  Plots  of  temperature, wind  speed, wind direction
  versus altitude  are available, as  well as joint wind-stability distributions on a
  monthly, seasonal and  annual basis.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
dental, ere.)
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                        FOR OFFICE USE ONLY
   SUPPORT METHOD (Check one)
    AGENCY STAFF (Intramural)
Funds Estimate"^
  I $15, 714
                 76
                                                 PROJECT OFFICER
                                                 Mr. Machta
                                                 RESPONSIBLE ORGANIZATION
                                                  NOAA
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
STARTING DATE

    1975
ESTIMATED COMPLETION
DATE
                                                                                 1977
     approximate not for Citation, tee AND SI-SIE 76A WHICH MAY NOT BE USED.
                                           81

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                         Form Approved
                                                                       OMB Wo. 158-R0081
                                                               PROJECT NO. (Do not ua« thtm tpac«J

                                                               SSIE
                                                              EPA-IAG-D6-E693- BEK
 TITLE OF PROJECT
 Cloud and Precipitation Modification  Effects of Pollutants  from Energy Production
 GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 R.F. Pueschel,  Ph.D.,  Physicist, Program Director  R.H. Proulx, Technician
 C.C, Van Valin,  Research Chemist                    H. Proulx,  Technician
 F.P- Parungo, Ph.D., Research Chemist               E. Ackerraan, Technician
 D.L. Wellman, Electronic Engineer        Nucleation Chemistry Group, APCL/NOAA/ERL
 NAME ANO ADDRESS OF APPLICANT INSTITUTION
 Atmospheric Physics and Chemistry Laboratory, R31
 National Oceanic and Atmospheric Administration
 Environmental Research Laboratories,  Boulder, Colorado
                                            80302
 SUMMARY OF PROPOSED WORK - (I) Objective!. (2) Approach. (3) Currant PUn» and/or Pro trim, (SCO word, or laaa. Omit contldantlal data).
   In the Smithsoninn Science Information Exchange, summaries of work in progress ar« exchanged with government and private acaoclaa aup*
 sorting research and are forwarded to investigator* who request such information.  Your summary is to be ua«d for thaaa purposas.
 (1)  Objectives:   Provide information  on the size, shape, and chemical composition
 of atmospheric  pollutants from power  plants under varying  moisture and background-
 pollution  conditions.   Develop criteria by which to assess  their impact on the
 cloud and  ice nuclei budget and solar and terrestrial radiative fluxes.  Provide
 recommendations for control measures  to minimize detrimental environmental effects.

 (2)  Approach:   Measure in-situ by aircraft 1) primary (flyash) and secondary  (gas-to-
 particle converted) aerosols, 2) gases that lead to particle formation, 3) infrared
 terrestrial  radiation.  Collect additional aerosol samples  for delineating the
 parameters that determine cloud nucleating and radiative effects, viz., particle
 size and size distribution, shape,  and elemental composition.   Independently, deter-
 mine the cloud  and ice nucleating portion of the aerosol.

 (3)  Progress:   1.   The Four Corners,  N.M.  power plant neither  destroys nor creates
 ice nuclei that act by the deposition and/or condensation  followed by freezing
 mechanisms.  2.   In the same plume, a gas-to—particle conversion mechanism creates
 cloud condensation nuclei at a rate of 10^ to 10^° per second.   3.  During the
 combustion process, water soluble sulfates and chlorides condense at the surface
 of flyash particles.  4.  Infrared  (8-14 ym)properties of  plume effluents are:
 transmissivity  = 0.82 ± 0.01; extinction coefficient = 0.99 ±  0.04 per kilometer;
 cooling rate =  0.64 ± 0.1 centigrade  per hour.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (M
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                           DATE

                                                                            October 1, 1976
                                      FOR OFFICE USE ONLY
 X
 •UUDS OBLIGATED
  130
   40
F.Y.
76
76TQ
                                               PROJECT OFFICER
                                                  John  W.  Tovmsend,  Jr.
                                               RESPONSIBLE ORGANIZATION
                                                 NQAA
NO. OP FUTURE YEARS TENTATIVELY
ASSURED 9EYONQ CURRENT F.Y.
STARTING DATE
 July 19-75
 ESTIMATED COMPLETION
I DATE
I   July 1980
* EPA Form 5760-1 (7-72)     REPLACES PHS FORM 166 AND St-SIE 76A W>»!.CH MAY NOT 8E USED.
                                               82

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form Afiprufed
                                                                        OUR Ha. I58-RMS1
               PROJECT NO. fDo not use this space)
               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
               EPA

                 EPA-IAG-D 6-E721-BDH
 ITLE OF PROJECT  T.SOJI atiOn and Identification of Water-Borne Pollutants
                                                      f* ff-r-.tacim..!?! t*f*+.ri r»
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENOAOEO IN THE PROJECT.               (an are at  the following  address)
   C, Wayne  Holley, Chief, Laboratory Branch          Tennessee  Valley Authority
   lyman H.  Howe, Research Chemist                     150 1,01 Building
   Lucy  E. Scroggie, Research Chemist                 fcth and Chestnut Streets
                                                         Chattanooga, TU  (615) T55-3135
NAME AND ADDRESS OF APPLICANT INSTITUTION   TeMleSSee Valley Authority
                                      Division of Environmental Planning
                                      268 U01 Building, kth and Chestnut Streets
	Chattanooga. TO
SUMMARY OF PROPOSED *ORK - (I) Objectives, (2) Approach, (3) Currem Plans and/or Progress (200 words or lesa. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-


 Objective—Laboratory studies will be made to improve analytical  procedures and pro-
 vide  acceptable alternate analytical methods for  several pollutants  in water samples
 from  energy-critical areas in the Tennessee and Ohio  Hiver Valleys.

 Approach—(1) acroleiu by voltammetry; (2) total  arsenic by voltammetry,  atomic
 absorption, and colorimetry; (3) zinc, cadmium, lead, and copper  by  voltammetry and
 referenced to atomic absorption; (k) digestion techniques for  suspended and dissolved
 metals  (Al, As, Ba,  Be,  Ca, Cd, Co,  Cr,  Cu, Fe, Hg, Mg, tto., Mo, Hi,  Pb, Sb, Se, 31,
 m, V,  and Zn) by atomic emission plasma and referenced to atomic absorption;
 (5) sulfate by ion chromatography (applicable to  air  and water);  (6)  particulates
 by polarized light microscopy (applicable to air  and  water).

 Progress-—(l) acrolein (work completed July 1975);  (2)' arsenic  (work completed
 September 19T6); (3)  zinc, cadmium,  lead,  and copper  (work scheduled for completion
 December 1976).
 'OtNTIFY PROFESSIONAL SCHOOL INVOLVED f.
              N/A
                                         SIGNATURE.OF
                                            C.  WayneHolley
                              10-5-76
                                       FOR OFFICE USE ONLY
          MF.TMOD •fC.';.-o*> ant-)
     ' C G 7 ) A T t. n C C N T FJ A C T
F.Y.

1976
                             TASK -NO.

                                1-6
                                                PROJECT OFFICER
          ne_ Holley_
RESPONSIOLE ORGANIZATION
     Tennessee Valley Authority
                           nt..1.1
                                                    Tliyia-inn  nf 1?nvi T
                      t.'O. OF FUTURC YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
                                                           May 7, 1975
                             ESTIMATl.n COMPLETION
                             DATE
                              Hay  6,  1980
 K'A r.n.,, 5740-1 (7-72)    HEPLACers PHS FORM IGS AND SI-SIE 76A *MICH MAY NOT BE USED.
                                         83

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                         Form Approved
                                                                       o.iin Ho.
                                                              PROJECT NO. (Do nut uje thta apace)

                                                              SSIE                    	
                                                              EPA-T.AG-D6-E721 - BDI
TITLE or paojECTjjevelopment and Evaluation of an  Integrated Approach to the Optimization
	of Nuclear Power Plant Radiological Surveillance  Programs	
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT. James A.  Oopold, Project Director, 401 Chestnut
St., Em.  201, Chattanooga, TN  37401; FTS 854-3175
B. B.  Hobbs,  Analytical Chemist,  Radiological  Hygiene Branch
L. G.  Kanipe, Analytical Chemist, Radiological Hygiene Branch
D. W.  Nix, Analytical  Chemist, Radiological Hygiene Branch
R. L.  Doty, Health Physicist,  Radiological Hygiene Branch
R. G.  Pall are, Healfh  Physicist-,  Radrinl ngigal  Hygiene Branch	_____
NAME AND ADDRESS OF APPLICANT INSTITUTION
Tennessee Valley Authority
401  Chestnut St. , Rm. 268
Chattanooga, TN  37401
SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach. (3) Current Plan* and/or Progress (200 words or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.
Objectives:
1.  To  develop and maintain  a  model quality assurance program  for  radiological surveil-
    lance.   The emphasis for this project will be  on development of a multiple-labora-
    tory program.
2.  To  develop improved radiological monitoring  techniques.
3.  To  develop an optimized  radiological monitoring program.

Approach :
1.  To  produce an analytical quality control document which can be used by radiological
    laboratories for quality control monitoring  of procedures, counting equipment,  and
    data handling.
2.  To  develop a program of  interlaboratory studies, standards, and analytical and
    counting procedures to use as standard methods in multiple laboratories.
3.  To  produce guidelines for  gamma counting and data reduction techniques.
4.  To  develop a cost-effective radiological surveillance program  through the use of
    statistical methodology, parametric studies, and improved sampling procedures.
Progress:
1.  A "Handbook for Analytical Quality Control in  Radioanalytical  Laboratories" has
    been produced in draft form.
2.  An  interlaboratory standards  and crosscheck'  program has been established.
3.  A report,  "Least-Squares Resolution of Gamma-Ray Spectra in Environmental Monitoring1
    has  been produced in draft form, relating to analysis using Nal(Tl) systems.  A
    study of Ge(Li) detector systems is underway.
    Statistical evaluation of  available surveillance data is underway.
4.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
                NA
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                               '          "
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD fCtVc/t
    MftCOTIATCDCONTflACT
    nrrst: ARCH GH
 UND:, G O L I G A T ED j V. Y .
S118K obi.;   |
S118K est.
              d.  1976
                                               PSO/ECT OFFICER
                                               RESPONSIBLE ORGANIZATION
                                                            James A. Oppold
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y,

  3  (through FY 1979)
                                               TVA,  Division of Environmental Plannin
J STARTING DATE

I  rfay 7,  1975
ESTIMATED COMPLETION -
DATE               |

February 28,  1981'
EPA Form 5760-1 (7-72)    HF.PLACES PHS FORM 166 AND SI-SlE 7GA WHICH MAY NOT BE USED.
                                        84

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PROJECT
                                                                          Form Approved
                                                                         OMB No.  US-Root! 1
                      PROJECT MO. fOo mil u« Ihi, ,pt,ci->
                      SSIE
                      EPA   	'	

                      BV-IAG-D6-E721-BDJ
              Remote Sensing of S02 Effects on Vegetation
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.                  Division of Environmental Planning
Herbert C. Jones  III (Project  Director),  Supv.,       Air Quality Research  Section
 Air Quality Research Section                           Tennessee Valley Authority
Cecil D. Sapp  (Principal Invest.), Biologist          E&D Building
                                                          Muscle Shoals, Alabama  35660
                                                          Phone: FTS 872-8342
Tennessee Valley Authority
E&D Building, Muscle Shoals,  Alabama
35660
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach. (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
   In Itu* Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private'agencies sup-
porting research and are forwnrded to investigators who request such information.  Your summary is to be us«d for these purposes.
This  research activity  involves testing,  refinement, and development of remote sensing
instrumentation and techniques for monitoring  the visible effects of S02 emissions from
fossil-fueled electric  generating stations on  terrestrial vegetation.   NASA will
collaborate with TVA in the project.   Low and  high  altitude  color, color infrared,
multi-spectral  scanning, and perhaps  other types  of imagery  and  ground-truth  data
will  be obtained for effects on soybeans  and mixed  Southern  pine-deciduous  hardwood
timber stands in the vicinities of the Shawnee and  Widows Creek  Steam Plants,
respectively, for both visual and automated interpretations.
 DENTIFV PROFESSIONAL SCHOOL INVOLVED
   .t/, i'fr. I
                                                 Tennessee Valley/Authority
CPA Form 5760-1 (7-72)    Rtf'LACES PHS FORM IG6 ANO SI-SIC 76A »HICM MAY NOT BE USED.
                                         85

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              U.&. LNVIRONMtNTAL t'ftO TL'CTION AGENCY
               NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                     O.M/1 No.
               PROJECT NO. fOo nul ,,«o till* «/>i>c Procre&fi (200 words or less. Omit confidential
 Objective:   The objective of the Black Mesa hydrologic  study is to define the  effects
 of mining and related activities on the water resources of an area in the northeastern
 corner of Arizona.   Overall effects of the proposed  35-year mining operation on the
 water  resources will not be known until completion of mining and rehabilitation.   How-
 ever,  many questions regarding the impact of mining  and related activities may be
 answered by monitoring the hydrology of small watersheds.   The technology of watershed
 modeling is sufficiently advanced so that the necessity of a lengthy precalibration
 period is eliminated.

 Approach;  Three watersheds of 400 acres each were selected along one of the principal
 tributaries in the area of mining to monitor the  hydrology of a watershed under natural
 conditions and throughout the period of mining  and rehabilitation.  Rainfall,  stream-
 flow,  sediment load, quality of water including trace elements and carbon derivatives,
 and  other data such as vegetal cover are being  collected.   Instrumentation of  three
 watersheds is desirable in case the actual progress  of  mining is changed from  the
 present plans.  Because of the remoteness of the  study  area and runoff characteristics,
 the  data collection program must be automated as  much as possible.

 Progress;  Three small basins were selected, and  monitoring installations constructed
 at all sites.  Reconnaissance has been made in  search of a suitable location for a
 monitor on Moenkopi Wash, downstream from the project site.  A major part of the
 instrumentation was purchased including stage recording equipment  (both float  and
 bubble gages), automatic sediment-sampling equipment, and a number of recording rain
 gages  to be placed at selected points in each basin. Minimal work was accomplished
 on the ground-water well-drilling.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
 denial, i-lc.)

           NA
                                        George H.'Davis
                                                                          Oct. 5, 1976
                                     FOR OFFICE USE ONLY
   SUPPORT METHOD i Oin-A ort.-J
    KlJSf AltCM C.H
     100.OK     76
PROJECT OFFICER
F. A. Kilpatrick  (703)  860-6846
HESPONSIOLE ORGANIZATION

USGS - Water Resources  Division
         STARTING DATE

          Apr  75
                                                                         ESTIMATLO COMPLETION
                                                                         DATE
                                                                               June 82
 LPA Fi»mS76D-1 (7-72)    RLPLACLS PH* FOHM I6& AND *U-SIE 7CA WHICH MAY NO1 UE USED.
                                           86

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                         Form Approved
                                                                       OMR NO. ns-aonni
                                                               PROJECT NO. fUo not use Mils .pace)

                                                               SSIE
                                                               EPA-IAG-D6-E77B-BBWa
II LE OF PROJECT
               Water  Data for Coal Mining
IVE NAMES. OEPAHTMCHTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
'ROFESSIONAL PERSONNEL ENGAGED. IN THE PROJECT.

Principal       Frank A.  Packard, Hydrologist,  U.S.  Geological Survey, Water  Resources
Investigator:   I&v.,  Rra. 300, 1305 Tacoma Ave.,  So., Tacoma,  WA 98402 (206)  593-6510


Project Dir:    G.  H.  Davis, Research Hydrologist,(address below)  (703) 860-6846
 AME AND ADDRESS OF APPLICANT INSTITUTION
                 U.S.  Geological Survey, Water  Resources Division
                 National Center, Mail Stop 407
                 Reston.  VA 22092
	Reston. VA  22092	
SUMMARY OF PROPOSED WORK - (!) Objectives. (2) Apprcach, (J) Current Plans and/or Progress (200 words or less. Omit confidential data).
   [n Ihi1 Smithsonian Scie-nci- liilurmution Exchange-, summaries or work in progress are exchanged with government and private ngeneies sup-
porlini; rrsturch siod ure forwarded to investigators who request such information. Your sunim&ry is to be used for these purposes.

Objective:  The State of Washington contains many coal  deposits of potential economic
significance.  Basic  water resources data are needed in the potential coal mining areas
in in  order to evaluate (1) the hydrologic problems involved  in  developing the  coal,
(2) the availability  of water for  producing or  processing the coal,  and (3) the envir-
onmental impact of  the coal mining activity.
Approach:   Water resources data will be collected and analyzed for three or more areas.
GW studies will emphasize availability of water  and protection  of shallow aquifers.
Streamflow data will  be collected  for analysis of low, mean, and  peak flow character-
istics.   Baseline QW  data will be  collected, especially selected  solutes, pH,
temperature,  and turbidity.
Progress:   Baseline studies at Gallop Creek in the northwestern part of the State are
in progress.   At the  lower station  on this Creek  downstream from a proposed mine  portal,
sampling at monthly intervals for common ions, nutrients, dissolved oxygen, suspended
load and benthic invertebrates is in progress.  Field measurements of discharge,  pH,
specific conductance,  and atmospheric pressure are also being made.  On a qu.-rterly
basis,  samples are taken for analysis of the dissolved species  of significant heavy
metals.
IDENTIFY PR«.»r ESSIONAL SCHOOL INVOLVED (A/
th-itt.il, .•*«•.!
                 N/A
                                          SIGNATUR£ OF PRINCIF^AL^ IN VESTIGATOR


                                          . George li. Davis-'	
                                                                              Oct.  5.  1976
                                       FOR OFFICE USE OMLY	
   SUPPORT METHOD (
   IICSL: At
ruwos OfLt

  35. OK
                 76
                                                PROJECT OFFICER
                                                J_-_A^Kilpacrick   (703)  860-6846.
                                                RESPONSIBLE ORGANIZATION

                                                U.S. Geological Survey^
                       NO. OF Fiiriint- YCARS TENTATIVELY
                       ASSURLO Ul YONO CURKFNT f.Y.

                                      0        	
                                                         STARTING DATE

                                                           April 75
ESTIMATED COMPLETIOI
DATE
  April 76__
 EPA r'.rn.57«t)-l (7-72)     Rf.PLACi:S PHS FOHM lt.1, AND SI-SIE 76A WHICH MAY NOT OE USED.
                                        87

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U.S. ENVtRONMLNTAL PROTECTION AGENCY
NOTICE OF RESEARCH PROJECT
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PHOJECT Preplanning
Jxtudy_o£_th/? HyxLrologic— Ef
GIVE NAMES. DtPARTMENTS, AUD OPFt
PROFESSIONAL PERSONNEL ENCAGED 1
Project Alvin J. F
Investigator: Div., 218
Project Dir: G. H. Davi
Form Approved
OMI! No. nH-KOOSI
PROJECT NO. (Do iwi use Ihl, ,pac:'t
SSIE
EPA
EPA-IAG-D6-E77B-BBW3
Study to Develop a Comprehensive Project Proposal for a
:iAL TITLE5 Of PHINCIr'AJ. INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
N THE PROJECT.
eulner, Hydrologist, U.S. Geological Survey, Water Resources
E St., Anchorage, AK 99501 (907) 277-5526
s, Research Hydrologist, (address below) (703) 860-6846
NAME AND ADDRESS OF APPLICANT INSTITUTION
U.S. Geological Survey, Water Resources Division
National Center, Mail Stop 407
Reston, VA 22092
SUMMARY OF PROPOSED WOWK - (I) Objectives, (2) Approach.  Current Plan* and/or Progress (200 word* or let*. Omit confidential iluta).
In thi- Smithsonian Science Information Exchancc, summaries of work in pr<>gre*s art exchanged with government and private agrnclcs sup-
Objective: The preplanning study will evaluate the probable hydrologic effects and the
kinds of hydrologic data n
in Alaska. It will outlin
and anticipated hydrologic
following: (1) determinat
operations and transportat
of baseline premining wate
in quality can be anticipa
hydrologic problems relate
for impact studies that wi
various development plans;
aid in the making of decis
compile existing informati
are needed and will estima
evaluated in an orderly ma
data in potential mining a
Progress: Two coal fields
Hydrologic reconnaissance
collection is under way.
stream gaging station and
merits at many sites in eac
eeded to assess the environmental impact of mining operations
e the most likely areas for development of mining operations
problems peculiar to those areas. It will include the
ion of surface and ground-water availability for mining
ion of coal to markets or shipping points; (2) determination
r quality in potential mining areas so that downstream changes
ted and monitored; (3) consideration of special artic
d to mining in permafrost areas; (4) develop a long-range plan
11 include alternative courses of action that will depend on
(5) arrange study areas and problems in priority sequence to
ions on the implementation of future studies. The study will
on to determine where and what types of hydrologic studies
te the cost of such studies so that the mining impact can be
nner. A. limited field recoqnaissance will be made to collect
reas where presently data are not available.
, the Susitna and Nenana were selected for study this year.
of the fields has been completed and systematic data
Data collection includes a continuous stage and discharge
miscellaneous discharge and water quality sediment measure-
fa field.
IDENTIFY PRO! L5SIONAL SCHOOL INVOLVED (Mi-i/i *-.*/, SIGNATURE OF PR/NCIPAL INVESTIGATOR DATE
N/A /:r 'George H. Davis Oct. 5, 1976


gACUNCv STArr ffnir.i'vHr.i/l

HCat: AMCM CH AN T
FOR OFFICE USE ONLY
TASK NO. PROJECT OFFICER

3 F. A. Kilpatri^k (703) 860-6846
RESPONSIBLE ORGANIZATION
U.S. Geological Survey
FUNDS OOLIC ATED 1 F.Y. NO. OF FUTURE YE ARS TENT ATIVEL Y 1 STARTING DATE ESTIMATED COMPLETION
1 ASSUHLD tlfYONO CUNUCNT F.Y. 1 DATE
45. OK 1 76 0 1 April 75 April 76
EPA Form S760-1 (7-72)      nCPLACI 5 PHS rOHU IC6 AND SI-SI6 76A »mrn MAY NOT OE USED.
                                                    88

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              U.S. ENVIRONMENTAL PROTECTION AGENCV
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                       OAW Na I
                                             PROJECT NO.  Objectives. (2) Approach, (3) Currcm Plans and/of Procres* (200 words or less. Omit confidential data).
   In the Smithsonian SeU-nce lufurmiilion Exchange, summaries of work in progress are exchanged with Government *nd private agencies sup-
 terting rcseurch und ure forwarded to investigators who request such information. Your •ununarjr is.to be used for these purposes.
 Objective;   To establish a  network for collecting hydrologic  information in  the  energy
 development  areas of the Chaco River basin  in northwestern  New Mexico, which will be
 complementary and supplementary to current  investigation.   The information is  to help
 d&fine baseline or present  water-quality  conditions of both surface and ground-water
 resources which will help determine the effects of present  and proposed energy
 development  in the area.
 Approach:  Operate a stream flow and quality station at the Chaco River at Chaco Canyon
 samples by Park S. Staff;  (2)'collect four  sets of samples  at 10 sites by single-stage
 point samplers; (3) operate significant peak quality station  at existing stream  flow
 station Chaco River near the mouth by automatic pump sampler; (4) collect and  analyze
 bed material samples for particle-size and  trace elements that may be transported with
 storm flow;  (5) collect and analyze chemically, samples from  10 wells from potential
 uranium mining area; (6) collect and analyze chemically, water samples from  alluvial
 bed of dry arroyos.
 Progress;  A gaging station, surface and  quality of water,  was established on  the Chaco
 River at Chaco Canyon National Monument.  An automatic pump sampler (PS-69)  was
 installed, and a pump sampler shelter was erected on the Chaco River near Waterflow,
 KM, which is near the river's mouth.  The automatic pump sampler is activated  for storm
 event sampling for both suspended sediment  and chemical quality analyses.  Also, a
 continuous temperature and  specific conductance recorder was  installed at this site.
 IDENTIFY PF-Or'lISSIONAL SCHOOL INVOLVED fWt
 uVrir.tf. i-ri*.)
               N/A
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                          «orge H.  Davis
                                                                             October  5,  1976
                                       FOR OFFICE USE ON_LY__
    SUPPORT MC TMOO i
    ACIMO ST AIT f
 FUNDS OBLIGATED
     40.0
76
                                                PROJECT OFFICER
                                                RESPONSIOLC ORGANIZATION
                      NO. OF Furimr YEARS TENTATIVELY
                      ASSURED 06YONO CUHRCNT F.Y.
                                        STARTING DATE

                                         April  76 _
ESTIMATED COMPLETION
DATE

        80
 EPA Torra S7oO-l (7-»)    HCPLAtTS PUS rORM IfiG ANO SI-5IE 76A WHICH MAY NOT nE USED.
                                          89

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              U.S. ENVIRONMENT*',, PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PROJECT
                                                                        Form A
                                                                      O.MB Ho.
                                                             PROJECT NO. {Do not use Ihi* apace>
                                              ___	.—.	
                                              SPA-TAG-D6-E77B-BBWb
             Characterization of Mine Drainage in Southeastern  Ohio
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Principal       Clifford G. Angelo, U.S. Geological Survey, Water Resources Division,
 Investigator:   975 West Third Ave., Columbus,  OH  (614) 469-5553

 Project Dir:    G. H.  Davis, Research Hydrologist, (address below)   (703) 860-6846
NAME AND ADDRESS OF APPLICANT INSTITUTION
                 U.S.  Geological Survey, Water  Resources Division
                 National Center,-Mail Stop 407
                 Reston.  VA  22092	
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach. 13) Currant Plans end/or Procrvsa (200 word! of less. Omit confidential data).
  In Ihr Smithsonian Scicnri> Information Exchange, summaries of work In progress urc exchanged with government and private agencies •up-
porting research and are forwarded lo investic.utors who request such information* Your summary la to be used for theaA purposes.
 Objective:   (1) To  document at a reconnaissance level the occurrence of basic inorganic
 and organic  constituents in surface and ground waters of the  coal raining regions  of
 Ohio; (2) to relate the water-quality  parameters  to basin characteristics; (3)  to make
 the basic data available to those concerned with finding a solution  to the problem of
 water-quality degradation from mine drainage.
 Approach:  About  150 sampling sites, predominately surface water,  but also a few  ground
 water, have been  selected in four small basins: (1) Huff Run which flows west towards
 Mineral City, Tuscurawas-Carroll Counties;  (2)  Snow Fork which flows  south thru Murray
 City, Hocking-Athens Counties;  (3) South Fork  Short Creek which  flows east toward Adena
 Harrison County and (4) Spencer Creek which flows  northeast toward Morristown, Belmont
 County.  The sites  will represent the  geologic framework, terrain, and mining practices
 in southeast Ohio.   During the study period, a number of samples  will be collected at
 each site in ordf.r  to obtain data representative  of different flow regimes.
 Progress:  Samples  have been collected and measurements of flow made  at irregularly
 spaced sites along  the  main stem in each basin. Each tributary was  field-checked and
 when field measurements indicated a low pH and/or  high specific conductance.samples
 were taken and discharge measurements were made.   The sources of  water producing  these
 conditions were traced  to their origin.  Snow  Fork and Huff Run were  found to be  quite
 acidic; traced to abandoned underground mine shafts and gob piles and open high walls
 of abandoned strip  mines.   Sulfate content in  the  two basins ranged  from 500 to 2400
 mg/1 and iron from  4500 to 21,000 mg/1.  South Fork Short Creek and  Spencer Creek had
 pH at mouth  of 7.9  and  7.6, respectively.  The tributaries originate  in reclaimed strip
 mines, generally  as overflow from strip ponds.  The sulfate content  in the Short  Creek
 basin ranged from 820 to 2630 mg/1 and iron from  20 to 1300 mg/1.  The HCO-. content
 was also high, ranging  from 220 to 536 mg/1.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED f.Mf.rr
              N/A
                                                           JVESTIGATOR
                           orge H. Davis
                                                                            Oct. 5, 1976
                                     FOR OFFICE USE ONLY
   SU^POHT METHOD (
FUNDS OBLIGATED  F.Y.    NO. OF FIITimr YEARS 1 SNTATIVFLY
                     ASSUHLO BE VOND CURRtNT F.Y.
    40.OK
76
                                              PROJECT OFFICER
                                                      Kilpatrick   (703)  860-6846
                                              RESPONSIBLE ORGANIZATION

                                               U.S.  Geological^Survey
                                                       STARTING DATE
                                                          April 75
                                                           ESTIMATED COMPLETION
                                                           DATE
                                                                            April. 77
EPA Form 5740-1 (7.72)    Rll'LAir.S CHi I OHM t(,b ANU il-SIE 76A WHICH MAY NOT BE USED.
                                       90

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        Form f\fi[>rui'cd
                                                                        Ain NO. ns-Knosi
                    PROJECT HO. (Do „„, „.„ ,,,,s

                    SStE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                              EPA-IAG-D6-E77B-BBttb
 ITLE OF PROJECT
                  Oiaracterization of Mine Drainage in Illinois
 ilVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 'ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Principal        Larry G. Toler, Hydrologist,  U.S.  Geological  Survey,  Water Resources
 Investigator:    Iliv., P.O.  Box 1026, 605 Ho.  Neil St., Champaign,  IL 61320
                  (217) 359-3918.
 Project Dir:     George H. Davis, Research Hydrologist,  (address  below)   (703) 860-6846
NAME AND ADDRESS OF APPLICANT INSTITUTION
                  U.S. Geological Survey, Water Resources Division
                  National  Center, Mail Stop  407
                  Reston, VA  22092
SUMMARY OF PROPOSED WORK - <1) objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
  In the Smithsonian Science- Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-

 Objective:   To document  at a reconnaissance  level,  the occurrence  and distribution of
 basic  inorganic and organic constituents  in  surface and ground  waters in the coal
 mining regions of Illinois.  To relate water quality to basin characteristics and make
 the  data  available to those seeking a solution to water degradation in mined areas.
 To enable continued or increased mining with a minimum effect on water quality.
 Approach;  A data network  will be designed and operated.  Data  will be analyzed,
 evaluated,  interpreted,  and published.
 Progress:  Twenty sites  were sampled, most four times, at locations in the Big Muddy
 and  Saline River basins  in southern Illinois.  All sampling was coordinated with
 routine sampling being done by Illinois  EPA  and more intensive  sampling by the Greater
 Egypt  Regional Planning  Commission.

 Samples collected in mining areas by USGS continue to show high concentrations of
 sulfate,  acidity and several heavy metals.

 Experiments were made on changes in pH,  alkalinity and bicarbonate between the field
 and  laboratory.  No changes intotal alkalinity were observed on about 20 samples,
 however changes in pH and bicarbonate/carbonate ratios were common.  Only field pH
 values are used and carbonate species are now determined. in the field for all samples
 with pH greater than 8.3.
IDENTITY PROFESSIONAL SCHOOL INVOLVEO (.V
Jfiir.il. i-rt-.)

              N/A
                                         SIGNATURE OF
                                                            INVESTIGATOR
George H.  Davis
                                    Oct. 5, 1976
                                      FOR OFFICE USE ONLY
   SUPPORT MLTHOO a'/n-t-A on,-)
     CSf AflCM OMAN
 FUNPS OOLIGATCD  F.Y
 20.OK
                 76
                                               PROJECT OFFICER
                                               .    _-           _
                                               RESPONSIPLE ORGANIZATION
                                                 U.S. Geological Survey
                      NO. OF FUTUHtT YEARS TENTATIVELY
                      ASSUKLO Uf.VONO CUHHENT F.Y.

                                    0
               STARTING DATE

                April 75
ESTIMATED COMPLETION
DATE
  Juno 1577
 EPA Form 5760-1 (7-72)    HO'LAlTS I'HS FORM 166 AND SI-SIE 76A WHICH MAY NOT PE USED.
                                        91

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
                                                                       Fornf A
                                                                     OMB No.
                                                             PROJECT NO. lUt, nal ujo 11:1, space,

                                                             SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                             EPA -IAG-D6-E77B-BBWb
               Assessment of the Hydrologic Effects of Strip fining in  tue
               New  River  Basin of Tennessee	
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Principal       Stanley P. Sauer, Hydrologist,  U.S.  Geological Survey,  Water Resources
 Investigator:   Div., A'-^IS, Federal Building,  U.S.  Courthouse, Mashville,  TN 37203
                  (615) 749-5424'
 Project Dir.:   G. H. Davis, Research Hydrologist,  '(address below)  (703)  860-6846
NAME AND ADDRESS OF APPLICANT INSTITUTION
                 U.S.  Geological Survey, Water  Resources Division
                 National Center, Mail Stop 407
                 Reston,  VA  22092
SUMMARY OF PROPOSED WORK - fl) Objectives. (2) Approach. (3) Current Plan* and/op Progress (200 words or less. Omit confidential data).
  In lh<- Smithsonian Scirnci* Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-

 Objective:  The objective  is to determine the effect on water quality, sediment-pro-
 duction, and  streamflow of surface mining in selected areas of Tennessee.   Unmined,
 actively mined, and  previously mined (reclaimed and unreclaimed) areas of  the State
 which are representative of the spectrum of  climatological, geologic, hydrologic, and
 morphologic variations found in the region will be  identified for data collection and
 analysis.
 Approach;  Existing  information will be reviewed, areas classified in terms of geo-
 morphology, coal  characteristics,  and mining and reclamation practices.  A reconnais-
 sance type QW investigation to determine the best areas of study will be undertaken.
 Progress;  LANDSAT imagery was used to characterize land cover in the basin.   Nine land
 cover categories  were identified and plotted on 7-1/2 minute base maps for the entire
 382 sq. mi. basin using a  computerized analysis of  LAHDSAT digital tapes.   A  composite
 map at a scale of 1:62500  was also prepared.  Gage  construction at five small water-
 sheds was completed.   These 1 to 5 sq.  mi. watersheds represent stripped and  virgin
 conditions.   Continuous surface water records ;,ave  been collected at each  site since
 construction  was  finished.  Water quality data  is collected at these sites weekly by
 the University of Tennessee.  An intensive sampling survey at 15 sites in  the basin
 was completed.  These sites were located along  the  New River main stem and the outlets
 |of the larger tributaries.  At each site 45  water quality parameters were  measured.  In
 addition, biologic data was collected at four sites.  Monthly water quality and sedi-
 ment sampling was initiated in November at five sites downstream from the  gaged,
 actively mined watersheds  and above the mouth of the New River.
IDENTIFY PROFESSIONAL SCHOOL IN VOL VtlO (M
tlcnr.it. .-I.-.J
               N/A
                                        George H.  Davis
                            DATE

                             Oct. 5,  1976
                                     FOR OFFICE USE ONLY
   SUPPORT ME. THOD , r/..-,-A .*..•>
    AC I: NCI STAI'F tin
FUNO1 OBLIGATED  F.Y.

   20.OK       76
PROJECT OFFICES
..F... Jl._KiIpat.rick	(703)  860-6846
RCSPONSIQLE ORGANIZATION
 U.S. Geological Survey
         STARTING DATE

          April -75
ESTIMATED COMPLETION
DATE
                                                                          April 77
                                       92

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                       O.WB No. 158-ROOS;
                                                              PROJECT MO. (Da not us. ,Ms an»i-e>
                                                              5SIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                              EPA	
                                                               EPA-IAG-D6-E77B-BBWb
                 Reconnaissance of the Effects of Strip Mining and Reclamation on the
                of Mpt-alg anrl  t-ha Bllf f p.rri ng  Characteristics  of a SI-ypaTti i T|  Indiana
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIOATORS OR PROJECT DIRECTORS AND ALL OTHE.
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Principal        William  J.  Shampine, Hydro-legist, U.S. Geological Survey,  Water
 Investigator:    Resources  Div., 1819 No. Meridian St., Indianapolis, IN 46202
                  (317) 269-7101
 Project Dir:     G. H. Davis, Research Hydrolgist, (address below)   (703) 860-6846
NAME ANO ADDRESS OF APPLICANT INSTITUTION
                  U.S. Geological Survey,  Water Resources  Division
                  National  Center, Mail  Stop 407
      	     Reston, VA 22092	
SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
   In tht- Smithsonian Sciencf Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting rust-arch and are forwarded to investigators who request such information. Your summary Is to be used for these purposes.
 Objective:   The objective  of this study is to monitor the changes that occur  in the
 concentrations of selected metals and  the  characteristics of the buffer system in the
 hydrologic  system adjacent to an area  to be mined.  The  area selected is  in the lower
 headwaters  of the Wabash River in southwest Indiana.  The data base will  range from
 pre  to  post mining  following reclamation.
 Approach:   It is expected  that samples collected monthly at five sites will be adequate
 to define  changes in water quality, although this frequency may be modified in response
 to a continuing data assessment.  Analysis of metals will include the dissolved phase,
 suspended phase, and those associated  with the bottom materials.  The buffer  system
 will be defined by  field measurements  of pH, acidity, and alkalinity; titration curves
 will be plotted for each of these determinations.  Other field determinations will
 include temperature, specific conductance, DO, pH, and discharge.
 Progress;   About 50 percent of the study area has been disturbed by mining.  It is
 anticipated that mining will be completed  and the land reclaimed into row crops by the
 end  of  June 1976.   In  addition to the  mine cut itself  (about 100 feet deep and 300 feet
 wide),  mining operations have expanded to  such extent that the main stream channel in
 the  watershed has been diverted  (by ditching) around the new operations.   As  yet, the
 chemistry of the system has not changed  significantly, at least not towards acid
 generation, but the diversion has caused a large amount  of sediment to be moved into
 downstream systems.  Considerable background data has been collected on the systems
 both downstream and upstream of the mining.  The natural drainage upstream of the
 operations  will serve  as an excellent  .control.  It appears that the lake  system is well
 enough  isolated from the mining operations as to be unaffected by the current mining.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (.Ui»Hc-.il.'
ill-mil. i-(.-.)

                  N/A                f<
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                          ieorge H. Davis
                                                                             Oct.  5, 1976
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD |C/I<-. k <'M,->
    VGtNCV iT AF-F ff/llr	llrij)
       L: AHCH CR AN T
 FUNDS O0LIGA7EO TV.Y.
      49.OK
                 '76
                                               PROJECT OFFICER
                                                F_._A_.__Kilpatrick   (703)  860-6846.
                                               RESPONSIBLE ORGANIZATION
                                                U.S. Geological Survey
                     HO, OF FUTURE YEARS TENTATIVELY
                     ASSUMED BEYOND CURRENT F.Y.

                                     0
STARTING DATE

   May 75
                                                                            ESTIMATED COMPLETION
                                                                            DATE
                                                                              June 77...
 EPA Fo,m 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH HAY NOT BE USED.
                                           93

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
                                                                       Form A
                                                                      O.Mfl Wo.
                                                             PROJECT NO. (Horn,/ u.e Ifil, ,(,,<;*)

                                                             SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                             E1EPA-IAG-D6-E77B-BBX
TITLE OF F>ROJECT
               Development of Instrumentation and Techniques  for Measuring
                         T.arlpn S tr eam.-
OIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
 Principal        Arthur G. Scott, Hydrologist, U.S. Geological Survey, Water  Resources
 Investigator:    Div.,  National Center,  Mail Stop 415, Reston, VA 22092 (703)  860-6837

 Project Dir:     G. H.  Davis, Research Hydrologist, (address  below) (703) 860-6846
NAME AND ADDRESS OF APPLICANT INSTITUTION
                  D.S.  Geological Survey,  Water Resources Division
                  National Center, Mail  Stop 407
                  Bpgt-on  VA 77flCl?   	
SUMMARY OF PHOPOSED WORK - (I) Obiettive&. (2) Approach. 13) Current Plant (ml/or Progress (200 word! or let*. Omll confidential data).
  In thr Smithsonian Scicnci- Information Exchange, summaries of work in progress are eschanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary Is to be used for these purposes.
 Objective:  To develop,  test, and field evaluate flumes, weirs,  and  other devices  and
 means suitable for  measuring sediment  and  debris laden flows, to develop an in-situ  in-
 strumentation system capable of measuring  the mass concentration of  sediment in water,
 to develop an acceptable s.ampler(s)  for measuring the discharge  of bedload sediment  par
 tides  so as  to  permit  the effects of  energy  development, particularly mining activi-
 ties, on streams to be  monitored.
 Approach:  Flumes,  weirs, and,other  types  of  control structures  are  being developed,
 tested, and field evaluated in the areas of oil shale and coal mining.  Photographic
 techniques are being investigated.   A  literature search will  be  made of commercially
 available suspended solids sensors compatible with the objective.  One or two instru-
 ments will be selected  for comprehensive laboratory tests.  An automatic sampling  and
 data logging  system to  operate in conjunction with the optimum sensor will then be
 designed.  The complete  package will be tested first under simulated field conditions.
 Promising direct-measuring bedload samplers will be calibrated to define their efficien-
 cies under various  conditions.  The  effects of such things as particle size, transport
 rate, bed form,  hydraulic condition, sampler  orientation, and degree of filling on
 sampler efficiency  will  be ascertained.  Appropriate samplers will be modified and/or
 new samplers developed and subsequently tested and  calibrated to provide improved
 operation.
 Progress:  Experimental  weirs and flumes have been  installed  on  the  Belle Fouche River
 in Wyoming, on Piceance  Creek in Colorado, and on a tributary of the North Fork of the
 Kentucky River,  Kentucky.   The state of the art in  photographic  techniques that might
 be applied to the problem of flow measurement is being assessed.  Although the equip-
 ment survey is only partially complete, a  Dynatrol  density gage  is being tested.   One
 of the bedload samplers  of primary interest is the  Hellcy-Smith  sampler,  whi-h is  a
 pressure-difference-type sampler that  has  been used recently by  several inves'tigators
                  SCHOOL INVOLVED (
                 N/A
                                        SIGNATURE OF
                                     M- George H.  DavJa_
                                                                           Oct. 5. 1976
   SUPPORT METHOD f
    CSt'AUCtt CM AM T

FUNDS OQLIGA1 T
     19 5K
                76
                                     FOR OFFICE USE ONLY
                     NO. OF FUTURf YEARS TENTATIVELY
                     ASSURED BEYOND CURRENT F.Y.

                      	            3
                                              PROJECT OFFICER

                                               P.  E..-Creeson	C703)_86
                                              RESPONSIOLE ORGANIZATION

                                               U.S.  Ceolo,»i_caj^_Surycv__
STARTING DATE

  April 75
ESTIMATED COMPLETION
DATE

   April 80
CPA Form S7o(M (7-72)    RFPLACl'S PMS fORM 166 AND SI-SIE 76A WHICH MAY NOT HE USED.
                                          94

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        Form fl
                                                                      OAIO Wo.
      PROJECT MO. (Do ™>/ use /hi,

      SSIC
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                               EPA-IAG-D6-E77B-BBX
TITLE OF PROJECT
 Development of Methods for  Characterizing and Monitoring Levels of  Chronic Toxicity
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Principal        Harry V. Leland,  Biologist, U.S.  Geological Survey,  Water Resources
 Investigator:    Div., 345 Middlefield Road, Menlo Park, CA 94025  (415)  323-2292

 Project Dir:     G. H. Davis, Research Hydrologist, (address below)   (703) 860-6846
NAME.ANO ADDRESS OF APPLICANT INSTITUTION
                  U.S. Geological Survey, Water Resources Division
                  National  Center, Mail Stop  407
      	      Reston, VA  22092	
SUMMARY OF PROPOSED WORK - (I) Objectives. (2) Approach, (3) Current Plans and/or ProgrcsH (200 words or less. Omit confidential data).
   In ttu- Smithsonian Scicnt'- Information Exchange, summaries of work in progress ere exchanged with government and private agencies sup-
porltnc. rexewrch and wre forwarded to investigators who request such information. Your nummary Is to be used tot these purposes.
 Objective;   Standard methods for characterizing and monitoring  toxic substances at sub-
 lethal  concentrations  in aquatic ecosystems  are not available.   The  general objective
 of this investigation  is to determine, through detailed studies of organisms, simpli-
 fied  (model)  ecosystems and natural  (field)  sites,  the extent to which trace contami-
 nants  (especially trace metals)  in different aquatic environments are available for
 biological uptake, influence the production  and structure of plant assemblages, affect
 the growth and production of animals, and  thus  determine the trophic relationships and
 composition of aquatic communities.
 Approach:  Reservoirs  of trace contaminants  in aquatic environments  for bioaccumulation
 and the physico-chemical factors influencing solute metal availability and toxicity
 will be examined.  Methods of measuring  responses of aquatic communities to trace
 contaminants that are  applicable to water  quality monitoring programs will be evaluated
 Field studies in general will be conducted to verify results of laboratory experiments
 and to  Suggest problems needing further  study.   The reliability of monitoring methods
 for detecting population and community changes  due to the presence of trace contami-
 nants will also be determined.
 Progress;  An intensive field calibration  of the extraction techniques found most
 useful  in laboratory studies has begun.  Sediments and deposit-feeders (two clam
 species and two polychaete species) have been collected from 15 sites in San Francisco
 Bay and analysed for Ag, Cu, Zn, Fe, and Mn.   Several of the sites have been visited
 at different seasons and two sites have  been sampled intensively as  a function of time.
 Because of the complexity of metal-sediment-biota interactions  in San Francisco Bay,
 more data collection is necessary before final conclusions are  possible.
 O6NTIFY PROFESSIONAL SCHOOL INVOLVED f.Mci
              N/A
SlO^A7U«E,OF PR.^CJr*AJ_ IWVESTiqATOR

 George H. Davie'
                                                              ESTIGA

                                                                ' '
                   DATE

                    Oct. 5,  1976
                                      FOR OFFICE USE ONLY
   SUPPORT MCTHOO ((.'.'ii-.-J. .wi.
 FUNDS O'DL'IO'ATEO TF.Y.   TNO. OF FUTUKI vi»ns TENTATIVE
               I       ASSURLO at-YQND CuHfttNT F,Y,
 90.OK          76  |	   3
                                               PROJECT OFFICER
                                                  .E±_G.ree_son	(703J_86Q=.6B3JL
                                               RESPONSIBLE: ORGANIZATION
                                                U.S. Geological  Survey
STARTING DATF.

  April75
                                  ESTIMATED COMPLETION
                                  DATE

                                     April 80	
                                           95

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                      Form Approved
                                                                     OMB No.
                                                            PROJECT NO. (Do not ua* Ihia

                                                            SSIE
                                                            EPA-IAG-D6-E77B-BBX
TITLE OF PROJECT  Development of  Instrumentation for High-Volume Analysis
               Petrochemical and  Associated Compounds.
SIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

 Principal       A. Beetum, Hydrologlst,  U.S. Geological  Survey, Water Resources Div.,
 Investigator:   National Center,  Mail Stop 412, Reston,  VA 22092  (703) 860-6834

 Project Dir:    G. H. Davis,  Research Hydrologist. (address below)   (703) 860-6846
NAME AND ADDRESS OF APPLICANT INSTITUTION
                 U.S. Geological  Survey,  Water Resources Division
                 National  Center,  Mail Stop 407
                 Kesr.nn. VA   22092	
SUMMARY OF PROPOSED WORK - (I) Objectives. (2) Approach. (3) Cu
                                              nl Plans and/or Progress (200 words or less. Omit confidential data).
 Objective:  Develop  guidelines  to be used by management in choosing equipment for high-
 volume analysis of petrochemical and associated compounds.   In  addition, consideration
 of analytical methods  to be  used and software or hardware for data processing to be
 used in choosing suitable  equipment for research and development  in automation.  To
 develop guidelines to  permit managements choices consistent  with  longer term goals  to
 fully automate with  intermediate steps.
 Approach:  Plan a reasonable automated set-up that would maintain or reduce the stan-
 dard error of estimate on  analytical data, double analytical output, and reduce man-
 power requirements by  25 percent in comparison to that required presently.  Give
 several procedures where milestones can be reached as subdivisions of total goal
 Contract or inhouse  prepare  detailed specifications for equipment, software and data
 management system for  each milestone.  Initiate individual contracts to acquire equip-
 milestonetWare          ^^gement system for group or class instrument selected as a

 Zrogre^s:  Phase one to study the .feasibility of laboratory  automation was completed
 Phase two (system specifications) is in process.  The remaining phases are implemen-
 tation and installation, and then the system evaluation when all  components are install
 IclT "H ^C0mmendati011 wf  acquisition of integrated inhouse  computer facilities
 *nH rr M!      """Sement  and state of the art computer-integrated gas chromatographic
 and GC-MS systems.   These  systems should be operational before  proceeding with
 development of beyond  state  of  art instruments while current studies to plan and write
 the software for the data  management computers is in process
IDENTIFY PROreSSlONAL SCHOOL IN VOL VED (M,.;li ,.-.,1
              N/A
                                                                          Oct.
   SUPPORT METHOD (Ch.-ck UN.-)
TUN OS OBLIGATED  F.Y,
95K
                76
                                     FOR OFFICE USE ONLY
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y,

	3	
                                             PROJECT OFFICER

                                             , P.  E.  Greagon  (703) 860-6834
                                             RESPONSIBLE ORGANIZATION

                                              U.S.  Geological Survey
STARTING DATE

  April 75
                                                                         ESTIMATED COMPLETION
                                                                         DATE
                                                                            April 80
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-51E 76A WHICH MAY NOT BE USED.
                                           96

-------
              U.4. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
                                                                       l~nni\ Apfintt t-,f
                                                                      OHM Nu.  1-its-itnnni
                                                             PROJtCT HO. (Da nut „.•,<, 11,1, „,,„„•>

                                                             SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                               EPA-IAG-D6-E77B-BBY
TITLE Of PROJECT                                           	
Water' Quality and Geochemistry of Shallow 'Aquifers of Piceance  Creek,  Colorado
JIVC NAMf,. DEPARTMENTS. AMD OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
>ROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
Principal Investigate1":  Stanley F. Robson,  Hydrologist, USGS, Lakewood, Colorado
                          303 234-3815
Project Director:        George H. Davis, National Center, Reston,  Virginia
                          703 860-6846
                          U.S. Geological  Survey
                          Hydrologic Studies Section
                          Lakewood, Colorado  80225
SUMMARY OF PROPOSED WORK - (I) Objective!, (2) Approach. (3) Current Plan.
   In the Smithsonian Science Information Kxchan^c. summaries of work in progrcs
                                                      nd/oi
porting re
 Objective:
                                                         Progress
                                                        changed u
CBS.  Omit confidential data).
and private agencies sup-
	   The objectives of  the project are to collect detailed chemical  analysis of
the relatively shallow ground  waters that may be impacted by mining for oil shale and
associated minerals, principally in the Piceance and  Yellow Creek basins of Colorado.
The study serves to support  a  portion of an initial effort to improve predictive
geohydrologic and chemical models that may better  evaluate the impact of oil shale
mining on the hydrologic regime of the Piceance basin.   The total effort is designed to
develop the data base and analytical capability required to make evaluations.   The
existing state of chemical equilibrium .must be documented and studies of water quality
made  to predict effects of dewatering on water chemistry.

Approach:  Water samples will  be collected from approximately ten new wells and many
springs located in the Piceance Creek basin.  Chemical analyses for a broad suite of
parameters will be conducted on selected samples.

Progress:   Chemical  analyses of water from 10 wells and 48 springs were analyzed and are
being used  to  identify the source and distribution  of  major and minor ionic  species in
the Green  River Formation.   The dissolution of Nahcolite (NaHCC^) and the sources of
fluoride,  boron,  lithium,  and barium are of particular concern.  A complete  list of
chemical  constituents are given in the memorandum of agreement.  Copies of the chemical
analyses  are sent  to  the U.S. Environmental Protection Agency periodically.   A quasi-
three-dimensional  solute transport model of the ground-water basin was constructed but
could not  be properly calibrated.  The solute  transport model indicates that the distri-
bution  of  interaquifer flow calculated by a previous  flow model produces about 10 times
too much  mass  discharge to Yellow and Piceance  Creeks.  Data is being compiled and
analyzed  for use in constructing a profile-oriented solute transport model.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED fMudic.J/,
 tlcntfil, err.)
           N/A
                                                 OF PRINCIPALJJ^VE£TIGATOR
                                                     .
                                        C^eorpe  H .  Davis
    Oct. 5, 1976
                                      FOR OFFICE USE ONLY
    rtLSCAItCH CHANT
 FUNDS ODLICATED  r .Y.
    10.0
                 76
                      NO. Or FUTU«r YtARS TENTATIVELY
                      ASSUMED BEYOND CUdHENT F.Y.
                                              PROJECT OFFICER

                                              JFj_JV.__KilPatrick   (703)  860-6846
                                              RESPONSIDLC ORGANIZATION

                                               USGS, Water Resources Division
                                                       STARTING DATE
                                                         April. 1975
                                                                          fSTIMATEO COMPLETION
                                                                          DATE


                                                                           1980	
 EPA Fotrn 5740-t (7-72)    RLPLAULS PMS FOHM 1«i AND SI-SIE 76A *MICH MAV NOT lit USEO.
                                           97

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               „..». KNVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                           Form Approved
                                                                          OMB No.  H8-R0081
                                                                PROJECT NO. (Do not uam thia

                                                                S5IE
___	

 EPA-IAG-D6-E77B-BBY
T'Eo^?ec??6ncof Geochemical Data  in the Piceance Creek Structural  Basin  of Colorado
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
  George Saulnizr, Principal  Investigator,  USGS, Hater Resources Div., Colo. District Of
  uenver Federal Center,  Denver,  Colorado   80225
  J.E. Bleszcker, Project Supervisor, (Same as above)
NAME AND ADDRESS OF APPLICANT INSTITUTION

  J.E. Bieszcke, (Same  as  above)
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 word* or lava. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work In progress are exchanged with government and private agencies sup*
porting research and ars forwarded to investigators who request such Information. Your summary Is to be used for these purposes.
       The  purpose of  this project  is the collection and analyiis  of geochemical
  data on the relatively shallow ground waters  that may  be impacted by the  extraction
  of oil shale in the  Piceance  and  Yellow Creek Basins of Colorado.   Water  samples
  will be collected from approximately twelve wells and  many springs.  Chemical
  analysis  for approximately thirty peraroeters  will be collected on selected samples.
  Data will  be used to refine predictive models of resultant water quality  both for
  those waters encountered by mining operations and Niok waters centering surface
  drainages  and springs and seeps.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
dental, etc.)
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
   SUPPORT METHOD (Check o
    AGENCY STAFF (Intramural)
FUNDS OBLIGATED
                                       FOR OFFICE USE ONLY
                                                PROJECT OFFICER
                                                F.  A. Kllpatrick
                                                RESPONSIBLE ORGANIZATION
                                                USGS
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
                                                          STARTING DATE
                                                                                   specified
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                            98

-------
              O.S:1 ENVIRONMENTAL PROTECTION AGENCV
               NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                       f'nrm Approved
                                                                     OAI» /Mo.  J5S-ROOS)
                                       PROJECT NO. (Da not use 
             CONTHACT
    rccsr ARCH en ANT
 FUNDS OBLIGATED

     10.0
F.Y,

 76
                                               F. A. Kilpatrick	(703J_86-QrfiS46-
                         RESPONSIPLE ORGANIZATION
                          USGS,  Water Resources Division
NO OF FUTURE: YE&HS TENTATIVELY
ASSURED GEYONO CURRKNT F.Y.
              0
                                                       STARTING DATE
June 76
                 ESTIMATED COMPLETION
                 DATE

                   June  77
 EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND Sl-SIE 7SA WHICH MAY NOT BE USED.
                                            99

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE O.F
                                                                      O.VH Ho. I iX.KOOK I
                                                             PROJECT NO. (Da nul u«e il,ln .pace;

                                                             551E
                                                               EPA-IAG-D6-E77B-BBY
                      Ground-Water Reconnaissance  of- Fort Union between Yellowstone
                  Ml sqniiri
GIVE H1WES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.    (406) 449-5011,  2XE.  5302
Principal  Investigator: Don Coffin, Hydrologist, U.S. Geological Survey, Water Resources
Div., P.O. Box  1696,  421 Federal Bldg. ,  316 H. Park St.,  Helena, MT 59601
Project  Director:       George  H.  Davis, USGS,  National Center,  Reston, VA  22092
                         703 860-6846
NAME AND ADDRESS OF APPLICANT INSTITUTION
                         U.S. Geological  Survey
                         Hydrologic Studies Section
                         Lakewood, Colorado  80225
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress <200 words or less. Omit confidential data).
  Irt the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research find are forwarded to investigators who request such Information. Your summary is to be used for these purposes.
Objective:   The objective of  this study is  to  produce  and calibrate  a simulation
technique that projects the impact of large-scale  surface mining  of  energy fuels  in
southeastern Montana on the shallow ground-water and surface-water systems.  The  study
involves the collection of physical and chemical data  from existing  wells and  from
springs and seeps.  The effort  would be directed at  geographical  areas where coal is
most  likely to be developed,  in the Yellowstone River  basin and the  Upper Missouri
River basin near the Fort Peck  Reservoir.

Approach:   Initial efforts will locate existing wells  in the area of eastern Montana
between the Yellowstone and Missouri Rivers.   Field  efforts will  then involve  final
selection of representative wells and sampling.  Water levels will be measured to dis-
cover gross differences in the  potentiometric  surface  and maps will  be prepared showing
this  surface.   Modified pumping tests may be run if  pumps and observation wells are
available.   Samples of aquifer  water will be collected and analyzed  as shown in the
attached table.

Progress:   Approximately 5,000  well records  fi^ed  with the Montana Dept.  of Natural
Resources  S Conservation have been obtained  for the  coal rich areas  of McCone, Richland
Dawson, and Prairie Counties  Montana.  About 500 selected wells in McCone County  have
been  inventoried (location accurately determined,  depth and water level measured) and
about 50 water samples have been collected  for chemical analyses.  The well inventory
is complete in the Circle West  area, which  is  the  area where coal mining appears  most
imminent.   Field work is extending to nearby areas where coal is  known to exist.
IDENTIFY PROFESSIONAL SCHOOL INVOLVEO (Afcdicj/,
dental, ctc.l
                N/A
George H. |Davis
                                                                           Oct.  5.  1976
   SUPPORT METHOD (O,,-<-k on.-)
FUNDS OPLIGATCD
    16.5
                76
                                     FOR OFFICE USE ONLY
                                              PROJECT OFFICER
                                               F. A.  Kilpattlck	(703) 860-6846
                                              RESPONSIBLE ORGANIZATION

                                               USGS,  Water Resources  Division
                     NO. OF FUTURC VEAHS TENTATIVELY
                     ASSURED BEYOND CURRENT K,Y.
                                 zero
              STARTING DATE

                April. 1975
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT DC USED.
 ESTIMATED COMPLETION
 DATE

I  April. 1976
                                      100

-------
              U.S. ENViriOHMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
                                                                        l:ltrrt
                                                                      (Mil N,,.
                                                             PHOJECT NO. (Oo

                                                             5SIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFOOMATION EXCHANGE
                                                               EPA-IAG-D6-E77B-BBY
         OJtt  Reconnaissance of Surface  and Ground Water  System in Eastern  Utah  to
                     fg r.nnl .Mjpino; ,-inH Tjpl.-ifprl RnQTV Ai-M vi ri pg	
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLUS OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.     (801) 524-5663
 Principal Investigator:  James C. Mandorff, Hydrologist,  U.S.  Geological Survey,  Water
 Resources Div., 8002 Federal Bldg.,  125 So. State St., Salt Lake City, UT  84138
 Project Director:        George H. Davis,  USGS, National  Center, Reston, VA
                          703 860-6846
NAME.AND ADDRESS OF APPLICANT INSTITUTlOy
 U.S.  Geological Survey, 8002 Federal Bldg., 125 S^uth  State Street,
 Salt Lake City,  Utah 84138    801  524-5654
SUMMARY OF PROPOSED WORK - (I) Objectives. (2) Approach, (3) Current Plane and/or Progress.(200 words or irss. omit confidential d.na).
   In the Smithsonian Science information Exchange, summaries of work in progress arc exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary Is to be used for these purposes.
 Objective:  The objective of  this  study is to collect  and coordinate the  collection
 of baseline geohydrologic and geochemical data in an area of  the principal coal
 resources  in eastern and southwestern Utah to facilitate and  improve efforts  to describ
 the mechanisms determining impacts of mining on  the shallow and moderately deep ground
 water and  surface-water systems.   The study will, in cooperation with  the Bureau of
 Land Management,  involve a geologic and hydrologic  reconnaissance  type investigation
 in the  geographical area generally drained by the Colorado River system in Utah.  The
 purpose of the entire effort  is  to develop or refine an understanding  of  any  important
 mechanisms that may relate coal  mining, disturbed land reclamation, and subsequent coal
 preparation and use to any changes in the hydrologic regime and to develop therefrom a
 capability to  predict such changes.

 Approach:   (1) Identification of the principal areas of probable concern  in terms of.
 mining  and local use of coal  and possible impacts of these activities  on  the hydrclogic
 system,  (2) determine what data  are available t:o describe the hydrology  of the shallow
 and intermediate aquifers and surface waters, (3) identify existing wells and inspect
 for usefulness in delineating the potentiometric surface of principal  shallow aquifers,
 identifying structural controls  on the system, and  determining geochemical patterns.
 Water level data from these and  previous investigations will be contoured.  Water
 quality data from this and other investigations  will be examined to determine whether
 selected  data  may also be contoured.

 Progress:              Samples from wells and streams in eastern Utah are  being  collectc
  for chemical  analysis.  Samples are also being  collected from the coal
 regions in the Dirty Devil River drainage basin. These samples are being screened for
 possible  trace-metal determinations.      -,           s—s                     	
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED f.Wcdic.if,
 dental, etc.)
                N/A
                                         George H;i Davis
                   Oct. 5,  1976
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD (C/i<-cA *
                                               PROJECT OFFICER
                                                 F^A^JKilpntrick  (703) 860-6846_
 $25.OK
FUNDS OOLIGATED  F.Y.    NO. OF F UTUMT Y E ARS TENTATIVELY
                     ASSURED GEYONO CURRENT F.Y.
               76
                                               RESPONSIDLE ORGANIZATION
                                               	USGS_Jl_Water Resources Division
                              one
                                                        STAHTING DATE
April.  1975
                                                                           ESTIMATED COMPLLTION
                                                                           DATE
                                                                                    1977
 EPA Form 5760.1 (7-72)    REPLACES PtIS FOHM l<* AND SI-4IE 76A WHICH MAY NOT Ot USEU.
                                             101

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form Approvftl
                                                                        OMB No.
                                                               PROJECT NO. (Da not u» Ihft «p«cej
                                                               SSte
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                EPA-IAG-D6-E77B-BBY
TITLE OF PROJECT
                 Hydrology of Coal Spoils  Piles - Colorado
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Principal        George H.  Leavesley, Hydrologist, U.S.  Geological Survey, Water Resources
 Investigator:    Div., Bldg.  53, Denver  Federal Center,  Mail Stop 415, Box 25046,
                  Lakewood,  CO 80225   (303)  234-3815
 Project Dir:     G". H. Davis, Research Hydrologist,  (address below)   (703) 860-6846
NAME ANO ADDRESS OF APPLICANT INSTITUTION
                  U.S. Geological Survey,  Water Resources Division
                  National  Center, Mail  Stop 407
	Reston, VA  22092	
SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach, (3) Current Plant and/or Progress (200 word! or less.  Omit confidential data).
   In the Smilhsaninn Sc-icncL- liifurnuil ion Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting rcitvtjrch and ure forwurdcd to investigators who request such information. Your summary is to b« used for these purposes.
 Objective:   Water-quality  degradation potential of coal-mine spoils is currently of
 great interest.   To adequately  assess the  impact of surface mining  and to predict the
 effects of  future mining on unmined basins,  a hydrologic simulation model is  required.
 The accuracy with which the model will predict water-quality changes in the spoils pile
 and the subsequent effect  of the changes on  the water resources of  the basin  is a
 function of how  well the hydrology of coal-spoils piles  is  defined.

 Approach:   The hydrologic  data  collected during this study  will be  used to develop the
 water-quality component of a hydrologic  model which will simulate the  effects of coal-
 spoils piles on  the hydrologic  system.

 Progress:   Study site selection, lysimeter design selection, and  a  literature review
 are in progress.   Site selection will be finalized in August.  Equipment installation
 and data collection will commence as soon  after site selection as possible.
 DCNTIFY PROFESSIONAL SCHOOL INVOLVED (
                 N/A
                                         SIGNATURE OF PBINJZIPAL INVESTIGATOR
                                            s /  jf  ,*•  '^^ / ' /
                                                                              Oct. 5,  1976
   SUPPORT METHOD tCfu-1-fc niu-i
    ACI:NCY 5TAKFffrpfr.iruiir.ir)
      21.3
                 76
                                      FOR OFFICE USE ONLY
TASK NO.
    8
                                                PROJECT OFFICER
                                                JlJu_Kilpatric_k__ (703)  860-6846
FUNDS OOLIGATED JF.Y.   | NO. OF FUTURr YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
                                                RESPONSIBLE ORGANIZATION
                                                 U.S. Geological Survey
                            STARTING DATE
                                                          June 76
                                                ESTIMATED COMPLETION
                                                DATE
                                                                               June  80
EPA Form 5760-1 (7-72)
                   REPLACES PHS FORM 166 ANO'SI-SIE 76A WHICH MAY NOT BE USED.
                                             102

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              U.S. ENVIRONMENTAL I'HOTECTION AOEHCY
               NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        t'ttttn f\lljifm-i:tf
                                                                       iVn No. I
                   PROJECT NO. fOu

                   SSIE
                   EPPA-IAG-D6-E77H-BBZ
 TLE or PROJECT  Water Quality Monitoring in Yarapa and.Williams Fork Kiver  in
 IVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
 ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

 Principal Investigator: Richard  Grozier, Hydrologist,  U.S. Geological  Survey, Water
 Resources Div.,  Bldg. 53, Denver Federal Center, Lakewood, CO 80225 (303) 234-5092
 Project Director:        George H.  Davis, USGS, National Center, Reston, VA
                          703 860-6846
NAME AND ADDRESS OF APPLICANT INSTITUTION
                          U.S. Geological Survey, Water Resources Division
                          National  Center, Mail Stop 407
                          Reston, VA 22092	
SUMMARY OF P.ROPOSED WORK - (I) Objectives, (2) Approach. (1) Current Plans and/or Progress (200 words or leas.  Omit confidential data).
 Objective:   The objective  of  this study is to  collect detailed physical,  chemical? and
 selected biological data from the surface waters  of the Yampa ami Williams Fork Rivers
 that may be impacted by coal  mining and associated power plant facilities in the
 Hayden-Craig, Colorado area.   This study will  initiate work in documenting the existing
 baseline water quality conditions in the study area to permit future  assessment of
 possible impacts from coal development in the  area.
 Approach:   Water quality monitoring will be  conducted at the locations and for the
 parameters necessary to assess future impacts  in the geographical  study area.  Flow
 measurements will be made  at the time of sampling.

 Progress    Stream flow water quality monitoring equipment for stations on the Yampa and
 Williams  Fork Rivers have  been acquired.   Data collection and analysis for an extens'ive
 suite of  chemical and biological parameters  was initiated in August,  1975.
 IDENTIf-Y PROf- ESSIONAL SCHOOL INVOLVED (Mvt
 d.-m.il, ,.|C.)
           N/A
George H.  Davis
                                 DATE

                                 Oct. 5,  1976
    SUPPORT METHOD fO;,-i-A .irn-1
    nrsi:.\nrn CHANT
                                      FOi; OFFICE USE ONLY	
                            TASK NO.
    PROJECT OFFICER
    	F, ._A_._KiIpatrick	(703J 860-6,8,46^
    RESPONSIBLE ORGANIZATION
 FUNDS ODLICA1 "tftl I F.Y.   f«O. OF FUTUKC YEARS TENTATIVELY
                      ASSUHLO UEYOND CUfinCNT F.Y.
    21.26K
                76
      USGS.  Water Resources,Division
              ST AHTINC. DATE
                                                         April  1975
                                 ESTIMATED COMPLETION
                                 DATE
                                 April,  19SQ_.
 EPA FormiM-l (7-71)    HEPLACLS PUS FOHM IM> ANDS.I-SIE 76A *HICH MAY NOT (IE UJ..C.O.
                                              103

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              0,5. ENVIRONMENTAL. PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
                                                                        Vttnn A/iprtft'fJ
                                                                      OA1/I No. IW-KMIRl
                                                             PROJECT NO. (Do

                                                             SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                               EPA-IAG-D6-E77B-BB2
TITLE OF PROJECT  Water Quality Monitoring  on White River,  Parachute Creek  and Logan
               Waab,j.n_Qil__Shalg Areas of Western Colorado
GIVE NAMES, DEPARTMENTS. AHO OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Principal Investigator: Richard Grozier, Hydrologist, U.S.  Geological Survey,  Water
 Resources Div., Bldg. 53, Denver Federal Center, Lakewood,  CO 80225  (303) 234-5092
 Project Director:        George H. Davis, USGS, National  Center, Reston,  VA
                          703 860-6846
NAME AND ADDRESS OF APPLICANT INSTITUTION
                          U.S. Geological  Survey, Water Resources Division
                          National Center,  Mail Stop 407
  	Reston, VA  22092	
SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach, (3) Current Plans and/or Process (200 words or ICKS. Omit confidential data).
porting research and arc forwarded to investigators who request such information. Your summary Is to be used for these purposes.
 Objective:   To  collect detailed water quality data from selected surface waters in the
 areas of  western Colorado likely  to be impacted by oil  shale development.   The study
 will initiate several new water quality monitoring stations  and supplement  the para-
 meter coverage  at several existing stations.  The total effort will aid in  documenting
 the existing baseline water quality conditions in the oil shale area so that possible
 future  impacts  from oil shale  development can be evaluated.

 Approach:  There are two existing USGS monitoring stations located upstream and down-
 stream  from the Federal oil shale leases on the White River;  these stations will be
 supplemented for additional parameter coverage.  The  proposed Parachute Creek station
 will be established between two different oil shale projects and upstream from major
 irrigation  diversions to provide  baseline water quality data and monitor future impacts
 from oil  shale  development.  The  station proposed for Logan  Wash will  provide baseline
 data used to evaluate the water quality impacts of in situ oil shale development in
 that specific drainage,

 Progress:  Stream flow water quality  monitoring equipment for the Parachute Creek and
 Logan Wash  stations have been  acquired.   Data collection and analysis  for an
 extensive suite of parameters  was initiated in August,  1975.
                                           _C2_
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (,
              N/A
                                          George ». Davis
                                                                            Oct.  5T  1Q76
   SUPPORT METHOD (OVfft ..ri.->
                                     FOR OFFICE USE ONLY
                                              PROJECT OFFICER
    i.i -j\ «i"\_Ti L.M--I i                                v*j\*ij _ rfiiL.t.zL  jxcsou
 FUNPS OPLIOATLO Tf.Y.] NO. OT KUTU'a VE*'« TENTATIVELY       1S f^R T ING^ATe
                    I ASSUME.D OLVONO CUHMLNT F.Y.          |

    25-8^     I  76  I	     3	| April.  197
_!•_ A-. _Kilpatrick    (703)  8JO-6846
rRCSPONSIOLE ORGANIZATION
  JJSGS j_Water_ Resources  Division


                 1975
CSTIMATtO COMf'LCTION
DATE
                                                                                   man
 Ef*A Form 5760-1 (7-7?)    RtPLACl'S PUS FOfm 16ft *ND SI-SIE 7«* *H|C H MAY NOT HE USL'D.
                                            104

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PROJECT
                                                                         /"tirrn
                                              PROJECT NO. (lla i\M u,a 11:1,

                                              SSIE
                                                                   - IAG-D6 -E77B-BBZ
              _Surface  Water_Qualitv Monitoring  in Energy Development Areas
GIVE NAMES, DEPARTMENTS. AMD OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT OIHECTORS AND ALL OTHER
•ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.       (801)  524-5663
 Principal Investigator: James  C.  Mandorff,  Hydrologist, U.S.  Geological Survey, Water
Resources Div.,  8002 Federal  Bldg., 125 So.  State St., Salt Lake City. UT 84138
 Project Director:        George H.  Davis, USGS  National Center,  Reston,  VA
                           703  860-6846         '
NAME AND ADDRESS OF APPLICANT INSTITUTION
                          U.S. Geological Survey, Water Resources Division
                          National. Center, Mail  Stop 407
                          Reston.  VA  22092	
SUMMARY .OF PROPOSED WORK -  (1) Objectives. (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omil confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are cxchangedVith government and private agencies sup-
porting research and are forwarded to investigators who request such Information. Your summary is to be us«d for these purposes.

  Objective:   The objective of  this study is  to  collect water quality data  in  the oil
  shale and coal  development areas of Utah.  There are four  existing OSGS monitoring
  stations located  in the oil shale and coal areas and these stations will be  supple..
  mented for additional parameter coverage.  Along with the  monitoring of physical-
  chemical parameters,  a biological monitoring program will  also be initiated.   The total
  effort will aid in documenting  the existing  baseline water quality conditions in the .
  oil shale and coal development  areas so that possible future impacts can be  evaluated.

  Approach;  The  USGS will be responsible for  the collect-ion and analysis of surface
  water quality data in energy  impacted areas  of Utah.

  Progress:  Monthly samples are  obtained at each of four gaging stations as follows:
                  1. Field measurements of temperature, specific  conductance, pH,
                     streamflow, dissolved oxygen,  and alkalinity: monthly
                  2. Chemical analyses of all major ions: monthly
                  3. Nutrients:  monthly
                  4. Total organic carbon and dissolved organic carbon:  monthly
                  5. Total trace metals and dissolved trace metals:   As,  Al,  Be, Cd, Cr,
                     Cu, Fe, Pb, Li, Mn, Hg, Mo,  Ni,  Se, V, and Zn:  quarterly
                  6. Phytoplankton: monthly
                  7. Periphyton: quarterly
                  8. Suspended Sediment and turbidity: monthly
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Afcdtc.'d,
           N/A
                          George H'. ^Davis
                                                             Oct.  5.  1976
                                       FOR OFFICE USE ONLY
    SUPPORT METHOD fCJireli i»i<->
 FUNDS OflLIGATLD  F.Y.    NO. OF FUTURE YC 
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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                         UMB No.  ISS-ROOSl
                                                                PROJECT MO. (Do not uae rhfs apmca)

                                                                SSI E
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                 EPA-IAG-D6-E7 7 B-BBZ
TITLE OF PROJECT
 Collection of Geohydrologic and Geochrtmcal Data  in the Dirty Devil Drainage of  S.  Utah
OWE NAMES, DEPARTMENTS, AMD OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Kidd Waddel,  Principal  Investigator
 Ted Arnow, Project Supervisor
NAME AND ADDRESS OF APPLICANT INSTITUTION
 U.S. Geological  Survey, Water Resources Division
 125 South State  Street
 Salt Lake City,  Utah  84138
SUMMARY OF PROPOSED WORK- (1) objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or !••>. Omit confident!*! data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies aup-
porting reaearch and are forwarded to investigators who request such information. Your summary is to be used for these purposes.


The purpose  of  this project ts  to collect and evaluate baseline geohydrologlc and
geociiemical  data in an area of the principal coal resource  In  eastern and southeastern
Utah so as to facilitate efforts to describe the Impacts of raining on the shallow
and moderately  deep ground water and  surface water  systems.  The general  geogrpbllcal
area la that drained by the Colorado  River system In Utah with emphasis on the Dirty
Devil  drainage  system and  other (rincipal  basins where every development  is scheduled
and where such  development may  affect the water resource.  The effort will  Involve
consultation with site-specific investigators. Identification  of and measurements
at existing  wells and springs;  installation of a limited number of wells  at critical
locations and appropriate  a«jqifer analyses; analysis of ground and surface water
quality data, and additional  surface  water sampling.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
dental, etc.)
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD (Check one)
    RESEARCH GRANT
                                                PROJECT OFFICER
                                                F. A.  Kilpatrick
                                                RESPONSIBLE ORGANIZATION

                                                Interior,  USGS
FUNDS OBLIGATED
               F.Y.

                76
STARTING DATE

  1975
                                                                                   1977
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                           106

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 ITLEOF PROJECT Surface Water Quality Monitoring  In the Yellowstone River and  Its
_Iribiitaj:icaJ.n_UQrthern_Great_ilainsL_CQal_Rcgion.Qf -Eastern _Hontana_
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        OAtH Na.
                     PROJECT MO. 
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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                           Form Approved
                                                                         •OMB No. HS-R0081
                                                                PROJECT NO. (Do not uas Ihla apace)

                                                                SSIE
                                                                 EPA-IAG-D6-E77B-BBZ
T'surfacPeR°Water Quality Monitoring on  Tributaries of the  Yellowstone River in  the....
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.      ....powder R1 ver Coal  Region, Wyoming
  Sara W. West,  Project  Supervisor
NAME AND ADDRESS OF APPLICANT INSTITUTION
  USOI Geological  Survey,  Wyoming District Office
  P.O. Box 2087, Cheyenne, Wyoming   82001
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such Information.  Your summary Is to be used for these purposes.

  Problem
       Lack of  sufficient  baseline water quality data to monitor and  evaluate
  the  possible  impact of energy development activities on the tributaries
  of the Yellowstone River in the Powder River  Coal  Region.

  Objectives
       To obtain necessary baseline data to monitor and evaluate the  energy
  activities  on surface  water quality of the tributaries of  the Yellowstone
  River,

  Approach
       Under  a  Memorandum  of Agreement with the USGS the US6S will  sample and
  analyze the surface water at seven  stations.  The station  location, sampling
  frequency and parameter  coverage are as shown in the attached table.   It
  should be notad that there are many other water  quality sampling  stations
  established in toe area  and that the EPA-USGS program is an Integral  part
  of the overall  water quality sampling network.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED CMedjcaJ,
dental, etc.)
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD (Check o/iej
    NEGOTIATED CONTRACT
                76
                                                PROJECT OFFICER
                                                F.  A. Kilpatrick
                                                RESPONSIBLE ORGANIZATION
                                                Interior,  USGS
                                                         STARTING DATE
                                                              1975
                                                                                  1977
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                             108

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                            Form Approved
                                                                          OMB No. HS-R0081
   PROJECT NO. (Do not use this apace)

   SSIE
   EPA              ^^~^~~
    EPA-IAG-D6-E77B-BBZ
         ROJECT
 Collection of Geohydrologlc and  Geochemical  IJata  1n the northern Yellowstone River..
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Don Coffin, Principal Investigator.
 George  Pike, Project Supervisor
                                                                     ...and Missouri River
                                                                  Drainages of Montana.
NAME AND ADDRESS OF APPLICANT INSTITUTION
 U.S. Geological  Survey,  Water Resources  Division,  P.O. Box  1696, Helena, Montana,
 59601
SUMMARY OF PROPOSED WORK -  (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work In progress are exchanged with government and private agencies sup-
porting research aid are forwarded to investigators who request such information. Your summary is to be used for these purposes >

 To provide basic geohydrologic and geochemical data in the Northern Yellowstone  River
 and Missouri River drainages of  Montana with emphasis on potential coal development
 areas  (particularly Circle, Montana).  The effort will Involve the inventorying  of
 wells  in four Montana counties,  a  general  hydrogeologic analysis and appropriate
 mapping; water  level measurements; drilling of wells; aquifer tests and analyses;
 and ground water quality analyses.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
                                        FOR OFFICE USE ONLY
   SUPPORT METHOD (Check one)
                                                 PROJECT OFFICER
                                                 F. A. Kilpatrick
                                                 RESPONSIBLE ORGANIZATION
                                                 Interior,  USGS
FUNDS OBLIGATED
                .76
                       NO. OF FUTURE YEARS TENTATIVELY
                       ASSURED BEYOND CURRENT F.Y.
                                                           STARTING DATE
1975
                 ESTIMATED COMPLETION
                 DATf977
EPA Foftn 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                             109

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE         EPA-IAG~D6~E77B~BB2

TITLE OF PROJECT water  Quality Monitoring ot Missouri Kiver and  its Tributaries in
                                                                     OVIl No.
                                                             PROJECT NO. ri»o ttut uaa Ihltt

                                                             SSIE
              Northern Great Plains of North  Dakota
GIVE NAMES, DEPARTMENTS. AMD OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.      (701) 255—4011   ext *  502
 Principal Investigator: William  E.  Harkness,  Hydrologist,  U.S.  Geological  Survey, Water
 Resources Div.,  Era. 332, New Federal  Bldg., Third St.  & Rosser  Ave., Bismarck,  N.Dak.
 Project Director:        George H. Davis, USGS,  National Center, Reston, VA   *158501
                          703  860-6846
NAME AND ADDRESS OF APPLICANT INSTITUTION
                         U.S. Geological Survey, Water Resources Division
                         National  Center, Mail Stop 407
                         Reston, VA  22092
SUMMARY OF PROPOSED WORK -  (1) Objectives. (2) Approach, (3) Current Plans and/or Procre&s (200 word* or lefts. Omit confidential data).


 Objective:   The objective of this study is  to  continue the surface water quality
 monitoring  program established with the USGS in 1974.  Due to variation in climatic
 conditions  it  is necessary to continue the  monitoring effort for  a period of years to
 establish representative baseline conditions.   This is accomplished in part by the
 continuation of the previously established  four station monitoring network and
 supplementing  an additional two stations  to provide a more objective  basis for
 evaluating  the possible impacts of energy development activities  on surface water
 quality  in  the Missouri River coal region of western North Dakota.  To monitor possible
 impacts  on  aquatic ecosystems the study is  to  be expanded to include  the establishment
 of a biological monitoring program.  It should be noted that there are many other
 water  quality  sampling stations established in the area and that  the  EPA-USGS program
 is an  integral part of the overall water  quality sampling network.
 Approach:   The UriGS will be responsible  for the collection and analysis of surface
 water  quality data in energy impacted areas of North Dakota.
 Progress:   Samples for a complete suite  of  parameters are being collected and analyzed
 at  the  six sites.   Sediment sampling equipment has been obtained as  needed.
                                             
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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                           Form Approved
                                                                         OMB No.  HS-KOOS1
                                          PROJECT NO. (Da

                                          5SIE
                                          EPA	  —	

                                          EPA-IAG-D6-E77B-BBZ
  Surface  Water Quality Monitoring for energy  Impacted Areas in the Powder River...
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED m THE PROJECT.     ...Coal  Region and the Green  River Basin,
  Sam W.West, Project Supervisor            Wyoming
NAME ANO ADDRESS OF APPLICANT INSTITUTION
  USOI, Geological  Survey.  Wyoming District Office
  P.O. Box 2037
  Cheyenne, Wyoming  82001
SUMMARY OF PROPOSED WORK - (1) objectives, (2) Approach. (3) Current Plans and/or Progress (200 words or 1.... omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such Information, Your summary Is to be used for these purposes.
  Problem
  Lack of Sufficient baseline water  quality data to monitor and evaluate
  the possible impact of energy development activities on  the  waters  of
  the Powder and Green River Basin and their tributaries.

  Objectives
       To obtain necessary  baseline  data to monitor and evaluate the  energy
  activities on  surface water quality in the Powder and Green  River Basin
  and their tributaries.

  Approach
       Under a Memorandum of Agreement with the  USGS the USGS  will sample and
  analyze the surface water at 14 stations.  The station location, sampling
  frequency and  parameter coverage are as shown  in the attached table.   It
  should be noted that there are many other water quality  sampling stations
  established in tie area and that tie EPA-USGS program is  an integral  part
  of the overall  water quality sampling network.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
dental, etc.)
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD fC/iecA o
    AGENCY STAFF f7n(ramiira/J
    RESEARCH GRANT
FUNDS OBLIGATED
                F.Y.

                76
                                                 PROJECT OFFICER
                                                 F.  A. Kilpatrlck
                                                 RESPONSIBLE ORGANIZATION
                                                 Interior, USGS
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                                                          STARTING DATE
                                      1975
ESTIMATED COMPLETION
DATE
    1977
EPA Form 5760-1 (7-72)     REPLACES PHS FORM 16.5 AND SI-SIE 75A WHICH MAY NOT BE USED.
                                             111

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                       OMH .V...  I IK-HOOK I
                                                              PMOJtCT NO. (

                                                              SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                               EPA-IAG-D6-E77B-BBZ
TITLE OK PROJECI  Establishment of New Surface-Water  Quality Monitoring Stations  in  the
               J?owdeji_and_Greei]_Rivers_x>£_Wyomine-
GIVE IIAMF-S. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.       (3071  778-2220   fiXt  2111
Principal Investigator: Fred C.  lioner, Hydrologist,  U.S. Geological  Survey, Water
Resources Div.,  4015 Warren Ave.,  Cheyenne, WY 82081
Project  Director:        George H.  Davis, USGS, National Center, Reston, VA
                         703  860-6846
NAME AND ADDRESS OF APPLICANT INSTITUTION
                         U.S. Geological Survey, Water Resources Division
                         National  Center, Mail Stop 407
                         Reston, VA   22092	
SUMMARY OF PROPOSED WORK - (1) Objectives. (3) Approach. (3) Current Plans and/or Progrc
   In the 5m
                                                               : (200 v
                                                                        r less. Omit confiflcnti.il data).
porting research and are forwarded to investigators who request such Information, Your summary Is to be used for those purposes.
Objective:   The objective of this  study is to augment  a seven station  surface water
quality monitoring program established  in 1974 with  the addition of 14 new stations  in
energy impact  areas of the Powder  River coal region  and Green River basin in Wyoming.
This comprehensive monitoring  network is designed  to provide a more objective basis  for
evaluating  the possible impacts of energy development  activities on the water resources
of Wyoming.  The subject monitoring program was developed with assistance from the
Wyoming Department of Environmental Quality, Water Quality Division.

Approach:   The USGS will be responsible for the collection and analysis of surface
water quality  data in energy impacted areas of Wyoming.  '

Progress;   A new expanded sampling program is in progress and on schedule.   To improve
quality control_ one man has been  assigned specifically to this sampling program.
The water  quality data for the 1975 water-year report are complete.
IDENTIFY PROFESSIONAL. SCHOOL IN VOU Vt D (
           N/A
                                           George H. Davis
                                                                            Oct.  5,  1976
   SUPPORT MtTHOP ,O>,-cfc
    HC'ST »HCM OH AN 1
ruNus OULIOAI L
    98.2 K
                 76
                                      FOR OFFICE USE ONLY
                                              PROJECT OFFICER
                                              HESCONSIULE ORGANIZATION
                     NO. OF FUTUHC YL.AH5 1TUTATIVLLY
                     ASSUHl a DCYONO CultllCNT f.Y.
                                              _VSGS.i_Watcr_Resources_Dlvision	
                                                       STARTING UATE
                                                        _Aprtlr  ]975
EI'A Conn S76IM (7-7:)    REPLACI s CHS FORM 101. AND SI-SIE 76A WHICH MAY NOT lie USED.
                                            112

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B.  ENVIRONMENTAL TRANSPORT PROCESSES

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                       TABLE OF CONTENTS
                 Environmental Transport Processes
Agency




 EPA




 ERDA




 NOAA




 TVA
 Page




  113




114-122




  123




124-129

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••
U.S. ENVIRONMENT AL PROTECTION AGENCY
NOTICE OF RESEARCH PROJECT
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
t'nrrrj Aflprurc'i
OMII A',,. ItH-KOUKl
PHOJtXT NO. 111., „,„ „,.,. ,hi, ,,,,,jcr.)
SSIP
EPA
CHD
 ,TLE OF PROJECT MINERALOGY QF OVERBURDEN  AS  RELATED TO GROUNDWATER DEGRADATION
              IN THE STRIP MINING  OF  COAL
 IVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AMO ALL OTHER
 ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 DEAN L. KLOEPPER - Director, Energy Resources Division,  CSMRI
 JOHN S. FRYBERGER - Director,  Ground Water Consulting Activities, Engineering
                                                                         Enterprises
 BOB NEWPORT - Project Officer,  EPA, P.  0.  Box 1198, Ada, OK  ?4820
NAME AND ADDRESS OF APPLICANT INSTITUTION
 COLORADO SCHOOL OF MINES  RESEARCH INSTITUTE
 Post Office Box 112
 Golden, Colorado- 80401	
SUMMARY OF PROPOSED WOP
  In ih. Smiihs
 (1)  OBJECTIVE:  The objective is to develop a method of predicting potential ground
 water degradation  in strip coal  mining on the basis of the mineralogy of the overburden.

 (2)  APPROACH:   The approach is to determine the mineralogy of cores in undisturbed
 overburden  adjacent to spoil piles which have undergone extensive chemical and biologi-
 cal weathering.   Extensive ground water quality data will be gathered from wells
 drilled  through  and down-dip from spoil piles.  Using this data base, a method of pre-
 dicting  ground water quality in post coal strip mining operations will be developed.

 (3)  CURRENT PROGRESS:  This project was funded on December 22, 1975.  Due to adverse
 climatical  conditions in N.W. Colorado, initial drilling, coring and completion opera-
 tions were  delayed until March 22, 1976.  Coring operations have been particularly
 successful  except in spoil piles where high percentage core recovery In this uncon-
 solidated material has been difficult to attain.
 Portable well pumping and sampling equipment utilizing expandable packers for zone
 isolation has been successfully demonstrated.  Lysimeters and associated fluid recov-
 ery systems have been installed in selected wells.  Well sampling was begun  in June
 1976.  Analytical  data generated from the initial samples will consist of over 45
 parameters  from  approximately 25 samples.  Mineralogy of core samples are being deter-
 mined utilizing  X-ray diffraction and X-ray fluorescence.  The first interim report on
 this project is  on schedule and will be forthcoming in October 1976.
 A grant  amendment, R-804162-01-01, is directed toward expanding the "Scope of Work" out
 lined  in existing Grant 804162-01.  This amendment will  permit several additional
 mining  sites to  be studied, thus broadening the data base to include varying mineral-
 ogical and  climatological conditions and strengthening the accuracy and applicability
 of the predictive nature of findings formulated in the original grant.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED r,V- .ln.,1,
uVnM/, -It: i
N/A
SIGNATUHE OF PRINCIPAL INVESTIGATOR
DATE
                                     FOR OFFICE USE ONLY
                                             | PROJECT OFFICER
                                              PROJECT OFFICER
                                              Rooert Newport

                                             |'RESPON5iBLYoHGANIZ«TION
F UNO*1. OGLIOAT E O
F.Y.
76
NO Of-- FUTURE YEARS TENTATIVELY
AS'jUHtD BF.YONO CURRENT F.Y.
STARTING D A T t-
12/75
ESTIMATED COMPLETION
DATE
10/76
 EPA Form 5740-1 (7-72)
                   SEPLACF5 PHS FORW 165 AND SI-SiE 764 WHICH M «V NOT BE USED.
                                          113

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                  U.S. ENVIRONMENTAL PROTECTION AGENCY
                    NOTICE OF RESEARCH PROJECT
         PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
    TITLE OF PROJECT
    Effects  of  Cooling Towers on Weather
                                                                              Form Approved
                                                                            OMB No. IJS-RQ08I
                                                                   PROJECT NO. (Da not us* thim apace;

                                                                   SSIE
                                                                     EPA-IAG-D6-E6 81- BCD
    GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
    PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
    Principal Investigator:   Steven R. Hanna
                               Rayford P. Hosker
                                 Research Meteorologist
                                 Physical Scientist
    NAME AND ADDRESS OF APPLICANT INSTITUTION
    Atmospheric Turbulence  & Diffusion Lab.
    P.O. Box  E
    Oak Ridge,  TN  37830
    SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach. (3) Current PUni and/or Progres* (200 word! at It**. Omit confidential data).
      In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup*
    porting reaearch and are forwarded to investigators who request such information. Your summary is to be u»*d for the** purpose*.

    1.  The  objectives of this  project are to  study  the influence of cooling  tower geometry
        on a plume and to develop and test numerical cloud growth model for single cooling
        tower plumes.
                                                      2
    2.  A small meteorological  wind tunnel with 1 m   cross section will be installed and
        tested,  and multiple plume interaction studies  will be designed.  The ATDL
        numerical cloud  growth  model will  be applied to cooling  tower plumes at power
        plants  where observation programs  are  currently underway.

    3.  The  wind tunnel  has  been received,  the building plans drawn,  and the tunnel
        should  be ready  for  testing by Jan. 1, 1977.  The literature on modeling studies
        of cooling tower plumes was studied and a review written.   The numerical cloud
        growth  model was verified using observations from cooling towers at the Rancho
        Seco power plant and the John E. Amos  power  plant.  It is now being applied to
        towers  at Chalk  Point,  Md.
    IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
    denr«l, ere.)
                                                                                Oct.  7. 1976
      SUPPORT METHOD fCdect <
 Funds Estimate*
   I$90,000
76
                                          FOR OFFICE USE ONLY
                                                   PfipJEC-T OFFICE*? „
                                                    D.  Heyward Hamilton,  Jr.
                                                   RESPONSIBLE ORGANIZATION
                                                    ERDA
       NO. OF FUTURE YEARS TENTATIVELY
       ASSURED BEYOND CURRENT F.Y.
STARTING DATE

June  1976
^Funds approximate not for citation. "* *ND S|-S1E 7S* »HICH MAY NOT BE USED.
ESTIMATED COMPLETION
DATE
June  1978
                                            114

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                U.S. ENVIRONMENTAL PROTECTION AOENCY
                  NOTICE OF RESEARCH PROJECT
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                         Forrrt A
                                                                        OA1B No.
                                            PROJECT NO. !Do not use this space)

                                            SSIE
                                             _	

                                              EPA-IAG-ft-EBBl-ftCD
    rue OF PROJECT
         Effects y'f Entrainment
   IVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES Of PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
   HOFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
         C.  C.  Coutont
         Environmental Sciences Division
    AME AND ADDRESS OF APPLJCANT INSTITUTION
         Oak RT,Oge National Laboratory
         P. 0. Box X
         Oak Ridge, TN  37830
   ,UMMARY OF PROPOSED WORK - (!) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).

   Key Objective;  To  determine the relationships between mortality of  fish eggs and  larvae
        and stresses  (fluid induced, thermal,  chemical,  mechanical)  encountered in power
        plant cooling  systems.
   Critical Objectives:   1. To evaluate  the  biological effect of condenser tube passage,
        2, To evaluate the biological effect of the pump, 3. To evaluate the biological
        effect  of the  entire condenser cooling system.
   Specific Objectives:   1. Using engineering evaluation, evaluate the  mechanical and
        hydraulic characteristics of power  station pumps that contribute to damage  of fish
        eggs and larvae  (by October 1977).   2. Build a power plant simulator  (loop)  before
        the 1977 fish  spawning season.   3.  Spawn and rear sufficient  fish  so  experiments
        can be  satisfactorily analyzed.   4.  Determine the survival of fish eggs  and larvae
        after passage  through a. variety  of  test conditions  (begin experiments in April,
        1977; completion of 1st experimental series by June 1977).  5.  Determine if en-
        trainment increases susceptibility  to predation by larger fish  (begin experiments
        in April, 1977;  completion of 1st experimental series by June 1977).   6.  Define the
        impact  of entrainment on important  plankton species at offshore power stations
         (begin  experiments in July 1977; completion of 1st series by  September 1977).
        7. Report progress, results, and conclusions in a timely manner.
   IDENTIFY PROFESSION
                  NAL SCHOOL INVOLVED fAI.-.Hr.il.   SIGNATURE OF PRINCIPAL INVESTIGATOF
                                         FOR OFFICE USE ONLY
      SUPPORT METHOD (Oi.-i k or),•)
 Funds Estimate*
    $200,000
76
                               PROJECT OFFICER
                               D.  Heyward  Hamilton. Jr.
                                                 I RESPONSIBLE ORGANIZATION

                                                 JJEBDA-
      NO OF FUTURE YEARS TENTATIVELY
      ASSURED BEYOND CURRENT F.Y.
                                                           STARTING DATE
                                                            continuing
*Tunds approximate not for citation. « AND S.-S.E ^ *H,CH «*v NOT BE USED.
                                              115

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Effect of Entraj mrent in pooling  Systems on Fish  Eggs
 GIVE IIAMC3. DEPARTMENTS. AND OFCICIAl TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.                                f  .
Dr. Charles C.  Coutant, Project  Supervisor,  Environmental Sciences Division
      (615-483-8611,  ext.  3-6617)
D,-. J. Samuel  Suffern, Research  Associate, Environmental Sciences  Division
      (615-483-8611,  ext.  3-1591)
Mr. Robert J.  Kedl. Research  Encnneei . Reactor  Division (615-483-8611. ext.  3-1196)
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE
                                                                        mill ,\.... i*x-Kmm
                                                               PROJECT NO. (tlv i

                                                               S5IE
                                   EPA-IAG-D6-E681-BCD
NAME AND ADDRESS OF APPLICANT INSTITUTION
Oak Ridge National Laboratory
Dak Ridge, Tennessee  37830
SUMMARY OF PROPOSED WORK- (1) Objectives, (2) Approach, (3) Current Plans and/or Proems (200 word* or lets. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work In pro crest are exchaneed with government and private agencies «Up-
portinf. research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.
     The objective is to determine the location  in a simulated  power plant condenser
system where  physical damage  is  done to small aquatic organisms,  principally fish eggs
and larvae, that are entrained  in  cooling v/ater.   The engineering objective is to
provide design  criteria for condenser piping  and  pumps that will  minimize  damages.

     The approach is to pass  test  organisms  through a simulated condenser  cooling system
and to observe  itr.T.ediate and  latent mortality, or behavioral  changes that  could affect
survival.   Emphasis will be on  the pump design in current experiments since previous
work has concentrated or. the  condenser.  Effects  will be associated with specific
features of pump design and operation where  feasible, e.g. specific speed,  and net
positive suction head.  A  redesigned simulated condenser system is being constructed
for experimentation in the spring  of 1976.

     Marine and freshwater organisms will be  tested as available for collection or
laboratory  culture.
 IClENTIFf PROFESSIONAL SCHOOL INVOLVED fAI
 rf«-nfo/, tie.)
             N.A.
   SUPPOHT METHOD fO,,-cJi one)
  RESi. ARCH GH *

Jh'JS OBLtCATt'O


 250 K
                 76
                                      FOB OFFICE USE ONLY
TASK NO.


    2
                                               PBOJECT OFFICER
                                                 D. Heyward Hamilton,  Jr.
                                               RESPONSIBLE ORGANIZATION
                      NO. OF FUTURE YEAR5 TENTATIVELY
                      A55URCO PCYONU CUHHENT F.Y,
                                                 ERDA/Dlv. of Blomed.&Envlron.  Research
                                                        STARTING DATE
                                                C51IMATED COMPLLTl.
                                                DATE
                                                                              2/77
 EPA Fj.rm 5760-1 (7-/21    REPLACES PHS FORM 166 AND SI-SIE 7tA WHICH MAY NOT BE USED.
                                          116

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  Transport and  Dispersion of Refiner? Wastes in Freshwater Coastal Regions
  GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
   ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
  f.  Harrison -  Project Director,  Energy and Environmental Systems Division
  D.  McCown  -  Physical Oceanographer, Energy and  Environmental Systems Division
  NAME AND ADDRESS OF APPLICANT INSTITUTION
  Argonne National  Laboratory
  9700 S. Cass  Avenue
  Argonne,  Illinois— 60439	
                U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE .
                                                                          Form Approved
                                                                        OMB No. J58-ROOSJ
                                              PROJECT NO. (Do not a,, tht, .pace;
                                              SSIE
                                                                EPA-IAG-D6-E681-BCF
  SUMMARY OF PROPOSED WORK- (1) Objective*. (2) Approach, (3) Current Plans and/or Progree* <2pO word* or [e»e. Omit confidential date).
     In the Smtth»onl«n Science Information Exchange, •ummariee of work in progreaa are exchanged with government and private agenclea eup-
  Bortlng reaearch and are forwarded to inveatlgatora who requeat «uch information. Your luminary la to be uaed for theae purpoae*.
  The  dynamics  of oil-fouled receiving waters will be examined in a series of experiments
  to be  conducted off the Calumet Region  of Illinois  and Indiana, in  southwestern Lake
  Michigan.   Here, five oil  refineries discharge-oily processing-water-into the lake via
  the  Indiana Harbor Canal.  .In a .given experiment,  a quantity of Canal water will be
  tagged with a small amount of an inert, non-toxic  rare earth in aqueous solution.  At
  the  same time'and place a  quantity of oily refinery waste will be" released; this waste
  will have been tagged with an oil-soluble solution of a different rare earth.  (Rare
  earths form organic complexes which are soluble in oil).  Both  tagged quantities will
  move out the  canal and into the lake, dispersing in the normal  fashion.  The sample-
  station  layout in the canal will be fixed from experiment to experiment.  In the lake,
  nowever, the  sample-station layout will be unique  to each experiment  and will be deter-
  mined by the  observed limits of the polluted-water plume emanating  from Indiana Harbor.
  The  vertical  distribution  of the oily wastes  within the dispersing  water mass will be
  assessed by sampling  the oily surface film, water at the one-meter  depth, and water one
    ter  above the bottom at  each sampling station in the area of  plume  dispersion.  Water
  temperature-data^vill be: taken, at .all sampling"points, as welly because the IHC water
  forms  a  thermal plume as it moves into  Lake Michigan.  Samples will be analyzed for
  rare-earth concentrations  by neutron activation analysis.   This technique permits
  determination of the  environmental concentration of each rare  earth at levels as low
     10~10 g/unit of sampling (usually 7  ml).   Rare-earth elements  such as dysprosium,
  lanthanum, gallium, terbium, gadolinium,  and  samarium will  be  used.  Several experiments
  can  be conducted without any chance of  confusion by unwanted  detection of prior injec-
  tions .
   IDENTIFY PROFESSIONAL SCHOOL INVOLVEDYMacflca/.
                                           SIGNATURE/OF PRINCIPAL INVESTIGATOR
                                                                              DATE

                                                                             October  28,  1976
                                         FOR OFFICE USE ONLY
      SUPPORT METHOD CChec* onej
Funds Estimate*
  g70,000
F.Y.

 76
                                                 PROJECT OFFICER
                                                  J.O.  Blanton
                                                  RESPONSIBLE ORGANIZATION
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                                                           STARTING DATE
ESTIMATED COMPLETION
DATE
 Funds approximate not for citation.  »<> AND SI-SIE 76A WHICH MAY NOT BE USED.
                                          117

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                            Form Attftntft'tt
                                                                          (Ml/) No,  DR-ROOXI
                                                                 PROJECT NO. (Da no! nan Ihle apace)

                                                                 SSIE
                                                                      EPA-IAG-D6-E681-BCf
 TITLE OF PROJECT
      Ecological Studies Around Natural Oil  Seeps in the Santa Barbara Channel	
 GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

     Spies, R.B., Principal  Investigator,  Environmental Sciences Division
 NAME AND ADDRESS OF APPLICANT INSTITUTION
  Lawrence Livermore Laboratory
  P.O.  Box 808
  Livermore, Ca. 94550	
                                               Phone (415) 447-1100 ext  4057
 SUMMARY OF PROPOSED WORK -  (!) objective*. (2) Approach, (3) Current Plum and/or Progrei* (200 word, or leea. Omit confidential data).
   In the Smithsonian Science Information Exchange, luminaries of work In progress are exchanged with government and private agencies sup-
 porting research and are forwarded to Investigator* who request such Information. Your BUmmary !• to be uacd for theae purposes.

         The objective of this  study is to define the interaction of petroleum  hydro-
    carbons with-nearshore benthic-communities JLn.±he Santi  Barbara Channel utilizing
    the  excellent natural laboratories provided by  submarine  oil seeps.

         We have sampled the benthic communities at  two fixed  stations  every two  months
    since October 1975.  One of  these is  in  a natural oil seep  and the other is
    located in a  nearby non-seep area of  similar depth and sediment composition.   Our
    first two sets of samples  indicate that  there is basically  the same  community
    in the two areas,  but that the seep station has  about 15% more species and twice
    as many individuals.

         We are formulating questions in the  area of comparative  population biology,
    reproductive  cycles and microbial utilization.
OENTIFY PROFESSIONAL SCHOOL IN VOLVED (Modicvl.

           NA
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                              DATE

                                                                               27 Oct.  1976
   SUPPORT METHOD (Check
 UNDS OBLIGATED
  $140K
                                       FOR OFFICE USE ONLY
                             TASK NO.

                                  #2
                                                PROJECT OFFICER
                                                                Clinton W.  Hall
                                                RESPONSIBLE ORGANIZATION
                                                                AAES/ERDA
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
                               Three
                                                         STARTING DATE

                                                           June  1975
ESTIMATED COMPLETION
DATE
                                                                                 June  1980
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                           118

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                       Form Approved
                                                                     Cl.18 No../58-ROOgl
                      PROJECT NO. (Do „

                      SSIE
                                                              EPA-IA6-D6-E681-BCF
Long-term effects of hydrocarbons  on selected ecosystems and associated organisms
       ES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIOATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL. PERSONNEL. ENGAGED IN THE PROJECT.                            DI«t<-roH5 AND ALL OTHER

 J. W. Anderson, Ecosystems Department, Research Scientist. Marine Biology
 R. H. Bean,  Ecosystems Department,  Research Scientist, Environmental  Chemistry
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Battelle,  Pacific Northwest  Laboratory
 Ecosystems Department (Marine  Research Laboratory - Sequin, WA)
 Rlchland.  Washington   99352	
SUMMARY OF PROPOSED WORK - (1) objective,, (2) Approach, (3) Current Plan, and/or Progrea. (300 word, or 1....  Omit confidential data).
  In tho Smithsonian Science Information Exchange, summaries of work in progress are euhanfed with government and private agencle* sup-
porting, research and are forwarded to investigators who r*ooe»t such information. Your summary 1. to be t»ed for tbe.e.purposes.
The objectives and approaches of this research are described in the  following three
tasks:(1)  effects of long-term,  low-level petroleum hydrocarbon  (PHC)  contaminated
water (source 1s Prudhoe crude oil)  on the growth and reproduction of two sensitive
crustaceans  (araphlpods and mysids) exposed for more than one  generation.  As part of
this task, analytical methods will be developed and utilized  In  order to determlntethe
levels of specific PHCs 1n water,  tissue and sediment, (2) exchange of specific PHCs
between  oil, sediment, water and organisms from laboratory and field experiments using
natural  sediments and Prudhoe crude  oil.  A major phase of this  research 1s to determine
the availability of sedlment-sorbed  PHCs to deposit-feeding organisms, (3) alteration of
PHCs 1n  and  on oiled sediments under natural (field) conditions  and the effect on
recruitment  of benthlc organisms.  The changes In compositional  characteristics of PHC
1n oiled sediments placed 1n the Intertldal zone will be compared  to settlement and
growth of benthlc animals In this  substrate.

Progress Over the Past 12 Months:  Task 1. Cultures of both mysids  and amphlpods have
been maintained over a period of 7 months.  Offspring have been  reared to near maturity.
Large numbers of each species are  being exposed to a constant, flowing level of 0.2 ppm
total hydrocarbons, and this will  continue for a period of several months while growth
and reproductive parameters are  measured.  An efficient and valid  system for sampling
exposure water, employing a resin  column, has been developed  and 1s 1n use.  A method
for determining the concentration  of non-cyclic aromatlcs 1n  the system 1s 1n press
(Bean and Blaylock, 1977).  Task 2.  Results of experiments on the  uptake of naphthalenes
from water and sediment exposed  to oil (In 2 ways) by the peanut worm, Phascolosoma
agasslzii. are aJso 1n press (Anderson, et al., 1977).  Experience and knowledge gained
Tn these studies are aiding similar  research on the b1oava1lab1l1ty of PHCs on sediment
for the  clam Hacoma.  More detailed  analyses of PHCs 1n sediment and tissues have been
developed.   Task 3.  Oiled sediments 1n trays have been 1n the field for 7 months and
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (
              MA.
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                     FOR
yu
                                         OFFICE USE ONLY
   SUPPORT METHOD (Cl],-,-k (
FUNDS OBLIGATED  F.Y.
                                              PROJECT OFFICER
                                               	t\if  i—m—1=.
                                               1ESPONSIBLE ORGANIZATIO
                     NO. OF FUTURE YEARS TENTATIVELY
                     ASSURED BEYOND CURRENT F.Y.
                                 At
                                                       STARTING DATE
                                                             -I-
                                   ESTIMATED COMPLETION
                                   DATE
                                                                               -
EPA Form 5740-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                          119

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                        OMB No. U&-R0081
                                                                PROJECT NO. (Da not uae Oil* ,f*Cf)

                                                                SSIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                 EPA-IAG-D6-E681-BCF
TITLE OF PROJEC
long-term effects of hydrocarbons  on selected ecosystem and associated organisms
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
J. W. Anderson, Ecosystems Department, Research  Scientist,  Marine Biology
R. M. Bean, Ecosystems Department,  Research Scientist, Environmental Chemistry
NAME AND ADDRESS OF APPLICANT INSTITUTION
Battelle,  Pacific Northwest Laboratory
Ecosystems Department (Marine Research laboratory - Sequlm,  HA)

S"UMMA"RY"O~F" PROPOSE'o'VlORK - (I) ObjecYlves, C2> Approach. (3) Currant PUna and/or Progreaa (200 words or less. Onut confidential data).
   [n the Smithsonian Science Information Exchange, summaries of work in progresa are exchanged with government and private agenclee sup-
porting research and ure Forwarded to investigators who request such information. Your summary is to be ua«d for these purpoaas.

(continuation)

several  samples have been taken for determination of PHC composition.  Two samples  have
been taken for analysis of the numbers of species and individuals present in control
and  oiled sediment.
Each task will require additional research over  the next 12  months to provide more
complete answers to  the questions posed in the objectives.

References:
Anderson, J. W.,  L.  J. Moore, J.  H. Blaylock, 0. L. Woodruff, and S. L.  Klesser.
      1977.  Bioavailability of  sediment-soreed naphthalenes to the  sipunculid
      worn, Phascolosoroa aqaaslzii.  In:   Proceedings of Symposium on Fate and
      Effects of Petroleum Hydrocarbons in Marine Ecosystems and Organisms.
      Seattle,  November 10-12.  1976.(In  Press.)

Bean, Roger M.,  and J. M. Blaylock.   1977.   Characterization of volatile hydro-
      carbons in flowing seawater suspensions of Number 2 fuel oil.   In:
      Proceedings of Symposium., on Fate and Effects of Petroleum Hydrocarbons
      in Marine Ecosystems and Organisms.  Seattle. November 10-12. 1976.
      (In press.)
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
dental, *-fi-.J
                                         SIGNATURE OF PONJCIPAL INVESTIGATOR
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD 
-------
                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                           Form AppTovfd
                                                                         OMB No. J5S-ROOSJ
                PROJECT NO. f
                SSIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                EPS	
                EPA-IAG-D6-E681-BCF
  Transfer of Participate Pollutants, Including Sediment  Dispersed during offshore Const.
   E NAMES. DEPARTMENTS. AND orFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.                                             UTHtN

  Dr. Gary  C.  Goldman,  Project Head,  Marine  Ecology Division

  Mr. Roberto L. Castro,  Research Associate,  Marine Ecology Division
 NAME AND ADDRESS OF APPLICANT INSTITUTION
  Puerto Rico Center for Environmental and  Energy Research
  College Station
             PuBl-ho  gjfn  00703 _
 SUMMARY OF PROPOSED »ORK -  (1) Objective.. (2) Approach, (3) Current Plan. snd/or Prop.., (200 wort, or 1.... Omit confidential data).
   In lh»- Smith.uninn Science Inforinution Exchange, .ummarie. of w/ork in prograsa are exchanged with government and private agencies sup-
 porting research and wre forwarded lo investigator* who request such information. Your summary la to be used for th«ae purpoae..

           The overall goal of  this program  is to determine the potential ecological
sffects  resulting from possible  offshore  construction of  a powerplant   These effects
«>'-ld  be primarily the results of considerable res. spension of the sedi  P.LIL in the
area.
           The study area is  the  northern  basin of the Cabo Roto Platfor ,  -'hich is
iust  '^-est of. the  island of Puerto Rico, and about ten kilometers southwest of the
city  of  'teyaguez.  Puerto Rico
           The approach to the  problem is  to determine the che::ical, physical, and
iyna:-leal properties of the  sediment in the basin.  This  is to be done  with both
surface  and  subsurface sediment.   The water current patterns will also  be  determined.
These  two paraneters will be combined, if possible to produce a 'projected trajectory''
of the sediment to help predict  the ultimate  location of  the material,  should it
be subiected to the resuspension.  Furthermore, the benthic oo:  .jnity will 'e
evaluated to atte"pt to nredir.t  the effects,  if any, that the new sediment load fay
lave  on  it.   Trace metal analysis will be carried  out on both the water and sediment
in the basin to determine what effect, if any,  will be seen chemically.
IDENTITY PROFESSIONAL SC HOOL IN VOL VEO (Vi-./.i-.il
r/Vnr-.rf, i-fc. )
   SUPPORT METHOD (On-rfc
                                       FOR OFFICE US^ONLY,/ L
XROJECT OFFICER
 J. O. Blanton
  250K
                76
                                                RESPONSIBLE ORGANIZATION
                                                ERDA
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
          STARTING DATE

              3/76
ESTIMATED COMPLETION
DATE
 EPA For- 5760-1 .'7-721     REPLACES PMS PCPM iee AND SI-SIF •'eA WHICH M*Y NOT BE user.
                                          121

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        Form Approved
                                                                      one NO. Ms-Roost
                                                              PROJECT NO. (Do not u«« thtt

                                                              SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                              EPA-IAG-D6-E681-BCF
TITLE OF PROJECT Transfer and dispersal of organic pol
       	into coastal waters.	
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENCASED IN THE PROJECT.

   M.D. Banus,  Scientist II, Head of project;  J. Castrillon,  Scientist II
NAME AND ADDRESS OF APPLICANT INSTITUTION
                                            Pollution Studies ,  Marine Ecology civ.
   Center  for  Energy & Environment Research
   College Station
   Mav^mip^. P.R.  Q07QS _
SUMMARY OF PROPOSED WORK - (!) Objectives, (2) Approach. (3) Current Plans and/or Pracrcas (200 words or !•••. Omit confident!*! data).
   In irw Smithsonian Sric-ncc Information Exchange, summaries of work in progress are exchanged with f overament and private aganclea sup-
purtine «• starch und are forwurded to investigators who request such information. Your summary la to be ua*d for theae purposes.
 Objectives: To  determine the amounts and  types  of hydrocarbon  pollutants in  the  air,
 water, sediments and various biological components of a tropical coastal ecosystem ad-
 jacent to the refinery-petrochemical complex at Guayanilla,  P.R.  To evaluate possible
 pathways for  these hydrocarbons through the  ecosystem, identify components which ef-
fectively store  or degrade hydrocarbons and evalute effect of hydrocarbons on local
 commercial seafood.   Finally, to develop and test a model of hydrocarbon transport
 applicable to tropical coasts to help predict impact of a refinery  on an unpolluted
 coast.
 Approach; A systematic sampling and analysis of air, water,  sediments at potential sites
 of input from the chemical plants and over a down-current grid as compared to a  pol-
 lution-free control.  Determination of principal hydrocarbon species.   Comparison of
 pollutant levels during wet and dry seasons. Hydrocarbon analyses  on plankton,  algae,
 benthic organisms,  fish (two or more feeding types)  and mangrove leaves and  roots.
 Mangroves may be a major pool and pathway  since the trees and  associated organisms are
 in contact with air, water and sediments,  since they are major energy converters of the
 ecosystem and,  since they are frequently in  the border between the  industrial complex
 and the coastal water.   Laboratory studies on the weathering or degradation  of hydro-
 carbons in tropical sea water and sediments.  Use of analysis  of variance and factor
 analysis to understand the relationship of hydrocarbon levels  prior to developing a
 model.
 First Year Plan:  Set up sampling grid and  schedule for water and sediments.  Select and
 use suitable  hydrocarbon extraction and determination methods.   Attempt to identify
 major hydrocarbon components using mass-spectrograph.   Start sampling and analysis of
 air and biological components of ecosystem.
  cNT!CY rr-.JF F SSION AL SCHOOL I N VO L V EO ( \lr,/l, .,(.

   Marine Ecology
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                   DATE

                    Oct.  11, 1976
                                      FOR OFFICE USE ONLY
   ' A C, F '.C v ST-\FF !lnir.,,,:,,r.il'<
   	
 •*•  •- • ':.-, - I ATf '- CONTRACT
 250K
                                              PROJECT OFFICER
                                               J. O. Blanton
                                              RESPONSIBLE ORGANIZATION
                                               ERDA
STARTING DATE
   3/76
                                           122

-------
                         riENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                         Form AppratftJ
                                                                       O.MB No.  I5S-ROOSI
                                               PROJECT NO. ro» „„, „„ ,„,. lp
                                               ssie
                                                              EPA-IAG-D6-E693-BEM
                Fate and Effects of Petroleum Hydrocarbons and  Selected Toxic'
                ' J- 	JJarine ~
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
                                          l.-lCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
           Douglas A. Wolfe, Project -Director
   M£ AND AOORESS OF APPLICANT INSTITUTION
           NOAA, Environmental Research  Laboratory
           Boulder, Colorado  80302
 SUMMARY OF PROPOSED WORK- <1) Objectives.  Approach. O> Current Plan, .nd/or Process (200 »ords or less. Omit confidential data).
   In the- S.-nithsonian Science Information Exchange, summaries of work in progress ar» exchanged with government and private agencies sup-
 porting research and are forwarded to investigators who request such information. Your sunuoary is to be used for these purposes.
 The overall approach  of this project will be to study experimentally  specific processes
 controlling the distribution,transport,and effects (both physiological and ecological)
 of  petroleum hydrocarbons and selected toxic metals in subarctic coastal marine ecosys-
 tems  to facilitate  the assessment of the impacts of petroleum releases in this ecosyste:
 type. The project includes four interdependent tasks with  the following objectives;
 a.  Establish a national KOAA analytical capability for petroleum hydrocarbons and toxic
 metals in the marine  environment for purposes of standardizing  analytical techniques,
 providing intercalibration services and conducting routine analyses on a contract basis,
 b.  Identify information gaps in our current understanding  of  petroleum impacts on sub-
 arctic marine ecosystems and design a.  comprehensive program of  laboratory and field
 research to fill  these gaps with reference to a particular,as yet unspecified, study
 site  to be located  in a coastal portion of the Northeast Gulf of Alaska.
 c.  Select, on a priority basis, and conduct specific laboratory experiments on fate
 and effects of metals and hydrocarbons.
 d.  Conduct controlled experimental ecosystem research to determine changes at the eco-
 system level and  to test our ability to predict ecological and  biological impacts of
 petroleum in subarctic ecosystems.
 Current approaches  or progress are, by objective, as follows:
 a.  Equipment has been purchased ana routine analyses of petroleum hydrocarbons in
 environmental samples are underway at  the NOAA National Marine  Fisheries Service
 Northwest Fisheries Center in Seattle, Washington.
 b.  A  major symposium/workshop was scheduled for November 10-12,1976 in Seattle,WA to
 identify current information" status and research requirements._
 c.  Laboratory experiments are underway to examine the interactions between PCBs and
 petroleua hydrocarbons in juvenile salmon and to determine the  effects of petroleum
 on  trace metal distributions between sediments and sea water.
 d.  Feasibility studies and experimental design are underway.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED f.V
 .-fr.ir.il. t-rc-l
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                           Douglas A. Wolfe
                                                            DATE

                                                            1 October 1976
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD fCfn-rfc •
 F'JMCS OBLIGATED
  478S
F.V.
76
76Ti
                                  1-4
                                               PROJECT OFFICER
                                                  John W.  Townsend, Jr.
                                               RESPONSIBLE ORGANIZATION
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED SEYONO CURRENT F.Y.
 STARTING DATE

:. August 1975
                                                            ESTIMATED COMPLETE
                                                            DATE
1980
'EPA FormSrSO-l (7-72)    REPLACES PUS FORM 166 AND SI-SIE 7SA *MICM MAY NOT BE USED.
                                           123

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                       Form Approved
                                                                      OMB No. D3-K0031
                                                             PROJECT NO. (Do not ua« this sp«c«)

                                                             SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                             EPA-IAG-D6-E721-BDL
TITLE OF PROJECT
               Atmospheric Interaction Studies
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGA
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Herbert C. Jones  III  (Project Director), Supv.,
  Air Quality Research Section
 J. F. Meagher  (Principal Invest.)> Research Anal.
 0. Huff, L. Stockburger, G. Shannon, and
 Elizabeth Bailey, Environmental Scientists
                                                      FORS OH PROJECT DIRECTORS AND ALL OTHER
                                                       Division of Environmental Planning
                                                       Air  Quality Research Section
                                                       Tennessee Valley Authority
                                                       E&D  Building
                                                       Muscle Shoals, Alabama   35660
                                                       Phone:  FTS 872-8342	
NAUE.ANp ADDRESS OF APPLICANT INSTITUTION
Division of Environmental Planning
Air Quality Research Section
Tennessee Valley Authority
E&D Building,  Muscle Shoals. Alabama
                                        35660
SUMMARY OF PROPOSED WORK - (!) Objectives. (2} Approach. (3) Current Plans and/or Progress (200 word* or lesa. Omit confidential data).
   [n the Smithsonian Scit-ncf [nfurmution Exchange, summaries of work in progress are exchanged with government and private agencies sup*
porting resirurch and .ire forwurdeu to investigators who request such information. Your summary is to be used for these purposes.
The primary objective of  this  project is to determine the chemical interactions  of con-
stituents  of atmospheric  emissions  from coal-fired power  plants  with particular  emphasis
on ascertaining the rates of oxidation of S02-  The ultimate  goal is to develop  the capa
bility  for predicting the concentrations of all major constituents of such  emissions at
various locations downwind.  Instruments are carried by an aircraft to measure the
fluxes  of  the constituents through  the plume at a number  of distances downwind.  Perti-
nent  meteorological parameters, such  as temperature and humidity, vertical  temperature
profiles,  wind speed and  direction, and solar radiation are measured with instruments
on the  aircraft and a ground station.   These data will be utilized to develop a  plume
chemistry  model which will detail the plausible mechanisms and kinetics of  chemical
reactions  occurring in the plume and  the meteorological influences on these reactions
so that the temporal and  spatial distributions and fates  of various plume constituents
may be  better understood and more accurately predicted.   Chamber studies of stack gases
are also being initiated  to obtain  some fundamental information  on plume chemistry.
Emphasis for the immediate future studies will be placed  on obtaining rates of oxi-
dation  of  S02 in stack gas.

A  preliminary study (four sampling  days)  was conducted in December 1975 - January 1976
at  TVA's Cumberland Steam Plant.  This plant has two 1300 MW  units each fitted with a
1000-foot  stack.   A second detailed study is planned for  this plant in the fall  of 1976,

Design  of  the reaction chamber has  been completed and bids are currently being sought
for construction.
                                              Tennessee Valley Authority
EPA Form 5760-1 (7-72)    REPLACES PMS FORM 166 AND SI-SlE 76 A WHICH MAY NOT BE US CD.
                                          124

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form f\pproi't-J
                                                                       O.1IO ,Vo.
                      PROJECT NO. (Do nor use thi,

                      SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                      EPA
                      PAIAG-D6-E721-BDL
               Regional Atmospheric  Transport of Coal-Fired Power Plant  Emissions
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER	
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.                  Division of Environmental Planning
Herbert  C. Jones III  (Project Director), Supv.,        Air Quality Research Section
 Air Quality Research Section                           Tennessee Valley Authority
Vinaya Sharma (Principal Invest.), Res. Analyst        S&D Building
Lawrence M.  Reisinger, Environ. Scientist
                 Muscle Shoals, Alabama  35660
                 Phone:  FTS  872-8342
NAME AND ADDRESS OF APPLICANT INSTITUTION
Division of Environmental Planning
Air Quality Research Section
Tennessee Valley Authority
E&D Building, Muscle Shoals, Alabama
35660
SUMMARY OF PROPOSED WORK - (1) Objective. (5) Approach. (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.
The  sulfur dioxide/sulfate issue requires development  of a scientific data base to
delineate regional effects of  coal-fired power plant emissions, and characterization
and  quantification of the mechanisms of long-range  transport of emissions.  A long-
range  transport model describing the conservation balance of S02/sulfate complex is
being  developed and  applied to a meso-scale region  (-/1000 km) centered  over the
Tennessee Valley watershed.  Among factors being considered are advection by wind field,
air  parcel trajectories, diffusion by atmospheric turbulence, source/sink mechanisms,
and  chemical transformations.  A regional S02 emissions inventory has been acquired
and  maintained by  continual updating.  A field study was conducted  in the spring of
1976,  and the data are being analyzed.   This will be of utility in model development
and  preliminary assessment of  the  overall problem.   During a later phase of the program,
data input will be refined and comparison data will  be obtained for model validation,
and  the  model will be upgraded.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVEO (Merlicut,
 aent.it, etc.}
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
 N/A
                                                Tennessee Valloy Authority
                                                                              9/27/76
   SUPPORT METHOD (Chc-ck one)
    AGFNCY ST AFF (Inir.tnmral)
    RESEARCH GRANT
     75
                                                                       '^ffi?fert C.
                                    'pert C. Jon-es,Ii:
                                                                            ESTIMATED COMPLETION
                                                                            DATE
                                    5/6/80
 EPA Form 5760-1 (7-72)    REPLACES PHS FORM ICG AND SI-SIE 76A WHICH MAY NOT OE USED.
                                         125

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               V-S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        t'ltrm A
                                                                      O.MB No.
                                                              PROJECT NO. (Do not uso thin space)

                                                              SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                              EPA-IAG-D6-E721-BDM
                                                              Radiological Impact Assess-
              	        Improvement of Models Used  for
              ment of Gaseous Releases  frog Nuclear Power  Plants
GIVE NAMES DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT. James A. Oppold,  Project Director, 401 Chestnut
St.,  Em.  201,  Chattanooga, TN  37401   FTS 854-3175
P.  H.  Jenkins, Health Physicist,  Radiological Hygiene Branch
R.  L.  Doty,  Health Physicist,  Radiological Hygiene Branch
W.  H.  Wilkie,  Health Physicist, Radiological Hygiene Branch
 NAME AND ADDRESS OF APPLICANT INSTITUTION
 Tennessee Valley Authority
 401  Chestnut St., Rm. 268
 Chattanooea, TN  37401
 SUMMARY OF PROPOSED WORK - (!) objectives, (2> Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).


 Objectives:
1.   To  evaluate and refine models used  for radiological impact assessment of gaseous
     releases from nuclear power plants.

2.   To  evaluate and refine models used  for radiological impact assessment of direct
     radiation from nuclear power plants.
Approach:
1.  To  place pressurized ionization  chambers at various locations around the Browns
    Ferry Nuclear Plant, for various  time periods.

2.  To  perform parametric analyses in conjunction with literature searches to improve
    the dispersion portion of the gaseous release model.

3.  To  refine models using available  data on power levels, effluent releases, meteoro-
    logical conditions, and environmental radiation levels.
Progress:
1.  While Browns Ferry was down for repair,  background radiation  levels were measured
    at  approximately 83 locations around  the plant.  A report  on  these measurements  is
    nearing completion.

2.  Models  have been and are being developed to determine the  presence and magnitude of
    the gaseous effluent plume.

3.  As  Browns Ferry returns to operation, additional field data are being collected.

4.  Preliminary comparative analyses  of available dispersion study data, parametric
    study results,  and dispersion code results  are underway.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
                 NA
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR     DATE
                                     FOR OFFICE U5EK5NLY
   SUPPORT METHOD fC/,,-cA om-J
                                              PROJECT OFFICER
                                              RESPONSIBLE ORGANIZATION

                                               TVA,  Division of
                                                           _James__A.L_Oppqld__
$44K est. exp.,  1976 [  3 (through FY 1979)
                                                       May 7, 1975
fUNOS OPLISATFD  F.Y.    NO. O F F u TU RE Y E 
-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Forirr Approved
                                                                         OMD No.  /5S.ROC8;
                     PROJECT NO. (Da nat uma Ihla space)
                     SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                     EPA
                      EPA-IAG-D6-E721-BDN
Simulation of  Thermal Dispersion and Fluid Mechanics at  Critical Locations in Streams  &
OIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHERReSCI VO3
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Richard J. Ruane, Supervisor, Spec.  ProJ. Staff, U01 Chestnut St., Rm.  2U6, Chattanooga.
   TH  37!*01   (615) 755-3167
William R. Waldrop, Res. Ens., Eng.  Lab., P.  0.  Drawer E,  Horris, TN  37828 (615) l^U-Tl: J
Richard C. Fanner, Consultant, Eng.  Lab., P-  0.  Drawer E,  Morris, TH  37828 (615) U9U-T1:
NAME AND ADDRESS OF APPLICANT INSTITUTION
Tennessee Valley Authority, U01 Chestnut Street, Room. 2l*8,  Chattanooga,  TH  371*01
SUMMARY OF PROPOSED WORK - (1) objectives. (2> Approach. (3) Current Plan* and/or Progress (200 word* or lean. Omit confidential data).
   In Ihr Smithsonian Science Information Exchange, summaries o( work In progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for the** purposes.

The study is  to extend and verify a theoretical computer  model of thermal effluents
from power generating  plants.  Such effluents  are generally three-dimensional and
turbulent.   The computer model which will be utilized is  a three-dimensional
unsteady finite difference technique.  This model is unique in that the conservation
equations of all three directions are solved in an efficient manner.   Most previous
models have  attempted  to describe a thermal effluent with two-dimensional equations
or at the very  most made restricting assumptions concerning transport in the third
dimension.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (
 if/A
                                          SIGNATURE OF PRINCIPAL INVESTIgA-TOR
Richard J. Ruane
                                   DATE

                                    9/29/76
                                       FOR OFFICE USE ONLY
   SU IMPORT METHOD ,O.
 v31i; est. cxpl  1976  3
                                                 PROJECT OFFICER
                                                    Willian  R.  Nicholas
                                                 RESPONSIBLE ORGANIZATION
                                                    TVA Division of  Environmental Planning
                F.Y.   FNO. or FUTU^I YE A 175 TENTATIVELY
                      ASSURED OtYOND CURRENT T.Y.
               STARTING DATE

                5/7/75
ESTIMATED COMPLETION
DATE
 vc./ao
EPA Form 5760-1 (7-72)     UKPLACKi Phi FuRM 166 AND il-ilE 76A WHICH MAY NOT BE USED.
                                           127

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        Form Approved
                                                                      OMB No. nfl-ROOSl
                                                              PROJECT NO. (Do not ua« l/ifa afwca>>

                                                              SSI E
                                                              __	

                                                              EPA- IAG-E6 - E72j^BDS
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PROJECT
Strip 1-line Drainage Water  Quality With Emphasis On Toxic Substances
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AMD ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
W.  R.  Nicholas, Branch  Chief, WQEB
R.  J.  Ruane, Supv., SPS
D.  B.  Cox, Snv. Engr.
R.  P.  Betson, Hydrologist, WSDB of DWM
                                       J. S. Grossman, Biologist,  WQEB
                                       W. C. Barr,  Biologist, Fisheries Branch
NAME ANO AOORES5 OF APPLICANT INSTITUTION
Tennessee Valley Authority.  Uoi Chestnut Street,  Room 267, Chattanooga, TH  37^01


SUMMARY Of PROPOSED WORK - (1) Objectives. (2) Approach, (3) Current Plan* and/or Progress (ZOO word* or less.  Omit confidential data).
   In the Smithsonian Science Infyrmution Exchange, summaries of work in programs are exchanged with government ao^ private agencies tup-
porting research and ure forwarded to investigators who request such information.  Your summary la to be used for theae purposes.
The objectives of this  project are to (1) identify  the occurrence and significance of
trace metals in a strip mined area; (2) calibrate existing regionalized hydrologic
models using data from  surface mined watersheds with several types  of reclamation;
(3) develop or extend nonpoint source water  quality models so  that  the natural-area
environmental loadings  of Important water quality constituents  can  be  predicted;
(k) relate the transport  of  significant trace metals and other  important water quality
constituents to the hydrology of small strip mined  watersheds;  (5)  develop relation-
ships between the chemical composition of strip mine overburden and the downstream
transport of important  constituents over and above  the natural-area environmental  levels
(6) relate the transport  of  important constituents  to the structure and function of
biological communities.
The goal of this project  is  to demonstrate methodologies for predicting the impact on
downstream biotic communities, based upon the characteristics of the site to be mined.
Sampling programs have  been  established at an area-mined (Jamestown, Tennessee) and a
contour-mined (New River  Basin)  site.  In addition  to routine water quality monitoring,
storm event sampling has  begun in the New River Basin and is planned for a site in
the Jamestown area.
Biological data have now  been collected for  four  months from five stations at the
Jamestown site.  These  data  have included baseline  qualitative  and  quantitative
information for periphyton and zoomacrobenthos plus downstream  drift information for
benthos.
Fisheries samples have  been  collected at four stations, two mined and  two control, in
the Jamestown area.  These stations are sampled each four weeks, weather permitting.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (
fjVrir.i.. cit-.l
                                                         .L INVESTIGATOR
                                                                            ..9/90/76
                                     FOR OFFICE USE ONLY
   SUPPORT METHOD (C/I4M-A tt(li-)
                                              PROJECT OFFICER
                                                W. R. Nicholas
                                              RESPONSIBLE ORGANIZATION
                                                Tennessee Valley Authority
FUNDS OBLIGATED

;iV5,ooo
          1976
                                                       STARTING DATE
5/7/75
                                                                           B/l/31
EPA Form 5760-1 (7*72)     REPLACES PHS FORM 166 AND SI-SIE 76A. WHICH MAY NOT BE USED.
                                        128

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          Form A
                                                                        twin NO.
              PROJECT NO. fDo I

              SSIE
                                                                             at uae this apace)
  TLE OF PROJECT  ~ ——————^

   PRODUCTION OF ARTHROPOD PESTS  AND VECTORS  IN COAL STRIP MINE POOLS
                                                                  EPA-IAG-D6-E721- BDT
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.


   Eugene  Pickard,  Entomologist, Water Quality and Ecology  Branch (princ. & Research Inve
   Dr. Joseph C. Cooney, Entomologist, Water  Quality and  Ecology Branch
NAME AND ADPRESS OF APPLICANT INSTITUTION
                                         Tennessee Valley Authority
                                         Division of Environmental Planning
                                         Water  Quality and  Ecology Branch
                                         Muscle Shoals. Alabama  35660	
SUMMARY OF PROPOSED WORK - (1) Objective*. (2) Approach, (3) Current Plans and/or Progress (200 words or Jess. Omit confidential daui
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be us«d for these purposes.
   Monthly field surveys are being conducted to qualify  and quantify arthropod
   composition in  strip mine pools according to pond age classification.
   Primary considerations are  to identify  and quantify the vector and  noxious
   species of arthropods present or to predict their appearance and importance
   as related to coal strip mining operations and seasonal changes.  Six  species
   representing two  genera of  mosquitoes have been collected from the  ponds.
   A total of 18 families of insects have  been collected by aquatic dip net and
   Ekman dredge sampling in the  9 study pools.  Results  from vegetation
   inventories have  shown a paucity of plants, both in species and in numbers.
   Typha latifolia and Scirpus cyperinus were the dominant plants in the  ponds.
   There appears to  be no significant difference in the  pH of the water among
   the  study ponds.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (
    N/A
                                                  OF SRINCIPAL INVESTIGATOR
                                                        c.
Eugene  Pickard
                                                            (.&«+H
                                                             ard  &
                                                                             September 27, 1976
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD (C/n-rA urn'J
    ; L-SI: AOCH GH AN T
      32,000    76
                             TASK NO.
                                                PROJECT OFFICER
                                                H. R.  Nicholas^ Chief, Water Quality & Ecol.
                                                RESPONSIBLE ORGANIZATION

                                                Tennessee  Valle^Auf-horj^ty;
FUNDJOOLIGATCD  I F Y.   TN'O OF FUTURE YEAHS TENTATIVELY
                      ASSURED GLYOND CURRENT F.Y.

                               3.0
                                                          STARTING DATE
                                                               9/75
                                                                             ESTIMATED COMPLETION
                                                                             QATE
                               FY 1981
EPA Form 5740-1 (7-72)     RLPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                           129

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C.   HEALTH EFFECTS

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                     TABLE OF CONTENTS





                        Health Effects







Agency                                               Page




 EPA                                                130-181




 ERDA                                               182-212




 NIEHS                                              213-261




 NIOSH                                              262-278

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                       f
-------
               U.S. INVIRO'IMLIITAL PhOl ECTICN AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          OMB .Vn. /'S-KOO.tJ
                                                PROJECT MO. (Do rat u.r Ik,, »,..
                                                S5IE
     PREPARED POP THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                   CKA
 ITLE OF PROJECT
 Effects of Exposure ta Aerosols Associated with Coal Conversion and Coal Combustion
 ,|VE KAME5. DEPARTMENTS, AMD OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 'ROFESSIONAL PERSONNEL ENGAGED IK THE PROJECT.
 'Walter L. Crider,  Project Officer,  HERL, PSD, EAB
 Ferris B. Benson,  Chief EAB,  HERL,  PSD
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Rockwell International Corporation,  Air Monitoring Center, 2421A West Hillcrest Drive,
 Newbury Park,  California 91320
 UMMARY OF PROPOStO WORK -  O) Obj«-ctiv<.-t. (2) Approach. (3) Current Pljns anrl/or Progress (300 »-orJs or less. Orait confident!*: .
   fn the Smithsop.l.-m Science Information Exc-hanijc, summnriei of work in progress ar« exchnng*d wi;h government dnj private agencies sue-
 wetlnc rrcciirch and are forwarded to investigator* wtra request such information. Your summary is lo be used for these purposes.
  (1) To monitor physical characteristics of aerosols and to obtain limited chemical com-
  position of aerosols through the use of commercially available automatic  instrumentation.
  (2)  To install automatic aerosol monitoring instruments  in  the Community Health Air
  Monitoring Program (CHAMP)'System.
  (3)  A contract was awarded  7-1-75 to Rockwell Air Monitoring Center to select and
  install appropriate automatic aerosol monitoring instruments in a few selected CHAMP
  field stations  and to integrate the data from these new instruments into the CHAMP data
  system.  The work on this limited effort is scheduled for completion 7-1-76.
 1OCNTIFT PfvOr ESSIONAL SCHOOL INVOLVED Pfe
 d.'f,r..r. r;c.)
                          SIGNATURE OF PRINCIPAL INVESTIGATOR

                           Walter L. Crider
                                                                               8/22/75
    SUPPORT METHOO l
     , CCILIGATEO
  $1300
76
                                        FOR OFFICE USC_p_r«LY_
             TASK NO.

                  1A
                                                  PROJECT OFFICER
                                                  Walter L.  Crider,
                                                  RESPONSIBLE ORGANIZATION
                                                  HERL, PSD
                       so. OP ruTjrc YEAR? TCMTATIVCLY
                       ASSUHEQ eLtONO CUHHENT F.Y.
                                          STARTING DATE

                                             7/1/75
f STIMATEO COMPLETION
DATE
 7/1/76
 SPA form 5760-1 (7-72)    RCPLACES PUS FORM 166 ANO SI-SIE 7tA WHICH MAY NOT BC USED.
                                             131

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NOTICE OF RESEARCH PROJECT
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
O.Md ,\.i. y-.i-ff(WIS;
PROJECT NO. (Oo not ua» IMm tptlce)
SSIE
CKA
I f Ltl OF PROJECT
Aerosol Addition to Cleans
live H AME5. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
•riOFGSSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Walter L. Crider
 Acting Chief,  Research  Services Branch
 Phone:   (919)  549-8411  x2601
SAME AND ADDRESS OF APPLICANT INSTITUTION

    Environmental Research and Technology
 UMMARY OF PROPOSED WORK-  (1) Objective, (2) Approach, (3) Current Plan* and/or Progress (200 word* or le»». Omit confident!*! data
  In lh« Smith* on inq Science Information Exchange, summariea of work In progrets at* exchanged with government and prtval* agencies sup-
 >'\if>Z research rtnd am forwarded to Investigator* who requast such Information. Your sumnury I* lo b» u*ed for thes* purpo****
           The  contractor  is to provide an aerosol  generating, monitoring and control
  system for one laboratory in the CLEANS facility.

           A competitive bid, const  plus fee contract, will  be negotiated for the design,
  installation  and integration of this  aerosol  system.  Performance requirements  will be
  limited to water-soluble aerosols  in  the 0.1  to  1  urn diameter range.

           A request for proposals will  be prepared  and advertised.  The successful
  contractor must be responsible for the compatibility of the new aerosol system  with
  the pre-existing CLEANS  system.  He also must provide for  the stability of the  aerosol
  generator in  terms of the output homogeniety  of  aerosol distribution  in the exposure
  zone of the laboratory,  etc.
:--ntal, elf.)

SUPPORT METHOD fC/iecfe one)

•.ECOTHTeOCONTnACT
rif ';I;ARCH GRANT
UK9S G 'LIG4TEO 1 F.V. NO.
$184. 9K 75 A"
$425. 6K 76
SIGNATURE OF PRINCIPAL INVESTIGATOR
DATE
FOR OFFICE USE ONLY
TASK NO.
	 1 A

1

PROJECT OFFICER
Walter L. Crider (919) 549-8411 x2601
RESPONSIBLE °"GAN,ZAT,ONResean.h Seryices Sranch
mniral StiirHp* OivisiOllj HFRI
OF FUTURE YEARS TENTATIVELY
JREO BEYOND CUHRtNT F.Y.
1
STARTING DATE
June 1975
ESTIMATED COMPLETION
OATF
July 30, 1977
   Form 5X40-1 (7-72)     REPLACES PHS FORM 166 AND SI-5IE 75A WHICH MAY NOT BE USED.
                                                132

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          f:nrm Approved
                                                                         O.Mfl No. 158-R0081
                                                PROJECT NO. fOo not use (Ms space)

                                                SSIE
                                                                     CKA
 ITLE OF PROJECT stationary and Mobile Facilities for Study  of Health Effects of
 Environmental Contaminants (CLEANS/CLEVER)	
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
 Edward Marsh
 Project  Director
 Computer Sciences  Corporation
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Computer Sciences  Corporation
 Falls  Church, Virginia
SUMMARY OF PROPOSED WORK -  (!) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omll confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-

       The contractor is  to  complete  the construction of the controlled environmental
 laboratory,  physical  facilities, and  computer programming, with which to conduct
 performance  tests to  insure satisfactory completion of the CLEANS system.

       The approach is  to complete construction of  these fixed facilities on site by
 April 1976.

       These controlled environmental laboratories  will be tested by  the contractor
 without human subjects  over the entire design range of gaseous pollutant exposure
 and environmental conditions.  These  tests will include manual control as well as
 automatic computer  controlled and programmed control.  After repeated demonstration
 of satisfactory performance of these  facilities,  tests will be started using  human
 subjects.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED nvfrrffrii/.
 denial, vti.t
                                          SIGNATURE OF
                                        FOR OFFICE USE ONLY
    SUPPORT METHOD fCl»-<-tt u
                                    1A
                                                 PROJECT OFFICER
                                RESPONSIBLE ORGANIZATION
                                .  RSB/CSD/HERL -
 FUN OS OBLIGATED
  $690K
  $265K
(74)
(76)
       NO. OF FUTURE YEAHS TENTATIVEL
       ASSURED BEYOND CURRENT F.Y.
 EPA F.,™, 57=0-) (7-72)    REPLACES PHS FORM .66 AND SI-SIE 76A WH.CH MAY NOT BE USEO.
                                       133

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                            Pnrm Aftpfourd
                                                                          own NO.
                                                                 PROJECT NO* (Do not ««• rhla mpmce)

                                                                 SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                     CKA
 CLEANS/CLEVER  Operation and Maintenance
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT;
 Walter L. Crider
 Chief
 Research Services Branch, Clinical  Studies  Division
 Health Effects Research Laboratory
NAME AND ADDRESS OF APPLICANT INSTITUTION

 Contract is  being negotiated
SUMMARY OF PROPOSED WORK - (I) OhjeiMivcs. (2) Approach. (J) Current Plant antf/or Progreaa (200 word! or laaa. Omit confidential data
   In Ihr SmiMiRonlnn Si-U-nic liirnrmtillnti Exchange, aumrnarie* of work In procraaa ar« exchanged with (overnmem and privet* agencies »up-
porting ri'arurvh urtd ure forwurdrd n» investigators who req'jetl luch information.  Your aummary Ji to b« ua«d for thaae purpoaaa.
 Objective:
       To obtain  a  contractor to operate and maintain the CLEANS/CLEVER
 systems.

 Approach:
       Proposals  will be  evaluated  and a contractor will  be selected.

 Current Plans:
       A  letter authorizing the successful bidder to  start work  will be
 issued  during the month of August 1976.  It  1s expected that  this contractor
 will  start developing a  work plan,  quality control  plan and a  safety plan
 for  EPA approval.  Actual  operation and maintenance should start September,
 1976.   A final  negotiated contract  is  expected by December,1976.
IDf'N Tlf Y PHOI 1 SSIONAL SL'MOOL INVOLVED (.Vf'J.'.iJ, SIGNATURE OF PRINCIPAL INVESTIGATOR
DATE
FOR OFFICE USE ONLY i
—i
XX
SUPPORT MfTttOO tCltt-t-t, mn-t


«esr ARCH en AN T
TASK NO.
1A
PROJECT OFFICER / . L jj-T' 	 ^ f *. ' ("!,
\jUQjC] Jt^_. 
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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                             /•orm Approved
                                                                           OMB No. 158-R0081
                                           PROJECT NO. (Do not ug« thlg apace)

                                           SSIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                            CKA
  rLEOF PROJECTEffects of Nitrogen Dioxide on  Pulmonary  Function  in Human
Subjects with Asthma and Chronic Bronchitis  .
GIVENAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL I
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   David Kerr; M.D.
 ssociate  Professor of Medicine
 Division of  Pulmonary Diseases
                                                  . INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 NAME AND ADDRESS OF APPLICANT INSTITUTION
University  of Maryland
School of Medicine
Baltimore.  Maryland  	
 SUMMARY OF PROPOSED WORK - (l) Objectives, (2) Approach. (3) Current Plane and/or Progress (200 word* or lets.  Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work Jn progress are exchanged with government and private agenclea sup*
 porting research and are forwarded to investigators who request such Information. Your summary la to be uaed for these purpose*.

      This study will  investigate  the  physiological changes in cardiorespiratory

parameters  in patients with  bronchial  asthma and chronic  bronchitis  to

two-hour exposures  of  0.3-0.5 ppm nitrogen dioxide in  clean air.   Results

from this investigation will  provide  data on the spectrum of  pulmonary

responses in two large classes of the  population at risk. The data will

aid  HSL in  further  defining  short-term adverse  effects of this pollutant.
                                  '6'f "M&d.
Baltimore Maryland
                    SIGNATURE OF PRINCIPAL INVESTIGATOR

                                     T.
    SUPPORT METHOD (Chrek orn-J
     RESEARCH GRANT
                                         FOR OFFICE USE ONLY	
                                                 [PROJECT OFFICER
                                    IB
                                                    Brock Ketcham. M.D.
                                                   ESPONSIBLE ORGANIZATION
                                                   USEPA/HERL/CSD/Physiology Branch
 FUNDS OBLIGATED
                 1976
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                                                            iTAHTING DATE
                                                                6/74
                                                              11/30/76
 EPA Form 5740-1 (7-7J)     REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                                 135

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               U.S. ENVIRONMENTAL PhOl CCTIOH AGEMCY
                 NOTICE OF RESEARCH PROJECT
                                                                           OMfl .Vn.
                                                  PROJECT NO. (Do mil u*r Ihi.t

                                                  SSIE
     PREPARED TOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                      CKA
TITLE OF PROJECT
IITL!:°r PROJECT Determine behavioral physiologic auid .metabolic effects, for .populations
residing in communities where major stuffs rn pollutants are anticipated from coai converslc
&IVE NAMES. DEPARTMLNTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER  /
PROFESSIONAL PERSONNEL ENGAGED IM THE PROJECT.                                   CO&1 COITibUStiOH.
                                                                                     ct
NAME AND AUDRESS OF APPLICANT INSTITUTION
SUMMAFW OF PROPOSED V.ORK - (1> Objective, (2) Ar>prcaeli, (3) Current Pljns artd'or Profreja ^200 woij» or Uxs. Omit canridrr.[i~i: dat
   In Ihu Smil^»or.inn Scivr.cr Information E&rh.^nep, fumrnarie* of u'oric in progress arc exchanged wi:h sovornmer.t and private- ag?ncl*» cup-
purtine rftc^rch and are forwarded to irivejtigator* who request ftuch informacion. Your luminary ia to be used fc; these purpotea.
    Policy decisions concerning energy production in the United States- must consider
among other factors, the effect of alternate techniques on the ambient exposure levels
of various pollutants and  consequent health  effects;   To address this issue,  studies will
be initiated to determine  behavioral,  physiologic  and metabolic effects  in  populations
residing in communities where major shifts in pollutants are anticipated from coal  conver-
sion  or coal combustion.  These studies will require better characterization of human
exposure to pollutants such as  sul'fates,  nitrates, and trace metals and  will involve a
major link with Task 1.

    The following  studies will be conducted  as part of this task.
IDt N 1 IFY pfsQt- tsSIONAL SCHOOL INVOLVED (\hdit.tl
a>-iti. COL.G* TFD

545K
76
                                  PROJECT OFFICER
                                  Jean G. French, Dr.  P. H.
                                                  RESPONSIBLE CH3ANI 2 ATION
                                                  RTF, N.C.
       NO. O»" FuTjfft VEAPS TC'IT AT1VCLY
       ASSUHE.D OCrONO CURRENT F.Y.
                                           STARTING DATE
EP* fo,m 5760-1 (7-72J
                            PHS FOHM >66 AND 5i-S)E 7GA WHICH MAY NOT BE USED.
                                           136

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               U.S. ENVIROflMLMTAL PhOTECTIOM AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                              Frirm .-^
                                                                            OHO .Vo,
                PHOjrCT NO. (Co nor u*r Ifii.i
                5SIE
     PREPARED TOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        CKA
                                                                       in
GIVE NAVES. OEPARTMCMTS. AND OFFICIAL TITLES Or PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Dr.  Bertrm Carnow, University of Illinois, School of Public Health, P.. O. Box 6998
Chicago,  Illinois 60680
NAME AND ADDRESS OF APPLICANT INSTITUTION
SUMMARY OF PROPOSED V.OPK - u> Ob;,-stiv,.s, (2) Approach, (!) Current Pljn. anll'or Profrc^s 1200 worjs or less. Omit con'identi.i: data
   In the Smithsonian Science Information Exrhnnc?. summaries of work in pic;re»s are exchanged with government and private agencies s-p-
porilne research aid ar* forwarded to investigators who request such information. Your sumfnar? is to be used for these purposes.

    The  purpose of this task is to  develop,  refine and test mathematical models to predict
changes in acute  and chronic health conditions  associated with changes in air pollution.
The effects  of changes in concentrations  of sulfur compounds are to be emphasized.
Existent health effects data and air monitoring data will be used to  develop and test the
models.  Finally prospective epidmiologic studies will be designed and conducted
specifically to test the model.
  l-MTIFY PFiOJ-CSSIOSAL SCHOOL INVOLVED C.VtJ.c./.,   SIGNATURE OF PRINCIPAL INVESTIGATOR
                                         FOR OFFICE USE 0:
 2SOK
                                  1.2/1
PROJECT orncER  Jean G.
Wilson Riggan, Ph.  D.
                                                   PROJECT orrictR  Jean G.  French,  Dr. P. H. and
RESPONSIBLE OHOANI2ATION
 RTF,  N. C.
F Y    1 SO. OF r UTjrc YEAS? T C'l T ATrvCL Y
       ASSUHCO DtiOriD CJHHENT F.Y.
76    I             2
                                                            STARTING DATE
                                                                 12/75
                              KST1MATLC CO^pL£T
                              DATE8/79
   i Form S7tO-l (7-72)     RCPLACES PHS FORM 160 AND SI-SIE 7iA WHICH MAY NOT SC USEO.
                                            137

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                U.S. ENVinONMLHTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH  PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                              OVFt .\ii MS-A'OO.'I
                                                                     PROJECT NO. f/)« not ua* rn^a

                                                                     SSIE
                                                                         CKA
 ITLE OF PROJECT Stuj  the effecto on asthmatics of pollutants resulting from converting to
 coal combustion M a power plant                                -                       f
GIVE NAVES. OEPARTMLNTS. ANO OFFICIAL TITLES Or PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER

PROFESSIONAL PERSONNEL ENGAGED 1" THE PROJECT.
NAME AND ADDRESS OF APPLICANT INSTITUTION
SUMMARY OK PROPOSED V.QRK -  (l) Ob-.ctivoi. (2) Apprf adi. (3) Currcr.i PUn* unrt/or Pr«,;fc*» (200 word a er less. Omit confide.iij.i: data).
   [n ihe Smiihsjoninn Sc inter Information Exc-har.gc, siim:narie* of work in prejrfh* are cxchangi-d wkh govctnmcrj and private agrncUt a-jp-
(twriinc r#««rarch and are f»r*'t.i-de-
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               U.S. ENVIRONMLNTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          f:(irrri Ajtfroi f.i
                                                                         OMB \o.  Ilg-Rnos
                                                           PROJECT NO. (Da no< ust i

                                                           5SIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                   CKA
TITLE OF p ojEc  gtu
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              U.S. CNVIRONMLMTAL PhOI CCTIOM AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Fftrm Apprtjt't'd
                                                                       OMfl .Vo, /'S-KOO.'/
                                                              PROJECT NO. f

                                                              5SIE
                                                               ITJT
     PREPARED TOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                    CKA
TITLE OF
 coal
      F FTOJECTgtu^y health status of a population living in the immediate vicinity of
      gasification plant botfiljeiore anfl during The operation of-trie plant.	
                                                                                     a new
GIVE MAWES. OEPARTMC^TS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
NAME AND AUORE5S OF APPLICANT INSTITUTION
SUMMARY OF PROPOSED V.OPK - u) Obj«-L-tivos. (2) Appre-acli. (}) Currcr.l Pl^ni unA'or Proi:ti» i200 * orj» or :«**. Omit confider.li;il <2aw)


     The purpose of this task is to assess the adverse health effects which may be
 associated with exposure to emissions from  a coal gasification plant.  Air, soil and
 water surfaces will be monitored within S kilometers of a new coal gasification plant
 before and after the operation of the plant to determine the levels of certain gases,  hydro-
 carbons,  metals and other specific  particulates.  One-thousand households in the
 same area will be interviewed before and one year after the operation of the plant to
 establish disease patterns.  Some 200 persons  representing a cross-section of the
 larger study  population will  have blood,  urine and hair samples analyzed for specific
 parameters twice before and twice after the plant becomes operational.  Both disease
 symptomotology and biological specimens will be compared with  emissions data.
lOI'NTIFY Pr,Ofr ESSiONAL SCHOOL INVOLVED fMeUic^i
ir**nr..l, ,-ft.j
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
* U'.t:^ OCLIG ATF.D
 S205K
                               < NO.

                                1.2/4
                                      FOR OFFICE USE^pri
                                               PROJECT OFFICER
                                               Jean G. French,  Dr. P.H.
                                               RESPONSIBLE O1OANI 2 ATION

                                               RTF,  N. C.
               76
                                      TENTATIVELY
  .
DC.VOND CURHENT F.Y.
   2
STARTING DATE

    4/76
                                                                           ESTIMATED COMPLETI3S
                                                                               3/79
EPA Fo,m S7CO-! (7-72)    HCPLACE5 PHS FORM 166 ANO 51-SIE 76A WHICH MAY NOT
                                          140

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               U.S. ENVIRONMENTAL PhOl ECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                PROJECT NO. (Do no* uar Ifti.

                S5IE
     PREPARED TOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                     CKA
   exposure
                                       Som^sWc-n7 3nd mortality in Populations with long-term
 IVE NAVES. OEPARTMCNTS. AND OFFICIAL TITLES Of PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
NAME AND AOORESS OF APPLICANT INSTITUTION
SUMMARY OF PROPOSED V-OPK - U) Ob-t-ctivos. <2) Approach. OJ Curror.i Plan* fip.rt/or Projrt-ia t200 worjs or less, o^iit confidcr.t:..: <±ala).
por!lnE rrcrarch «td arc forwarded to investigators who request such information. Your summary is to be used for these purpose*.

        The purpose of this task  is to compare specific disease morbidity and mortality
    rates in a population with high exposure to coal combustion emissions  for a prolonged
    period of time with rates in a comparable population without such exposure.   Particular
    attention will be given to chronic respiratory disease, cardio-pulmonary disease,
    cancer of the lung and birth defects.   In addition, unusual clustering of other disease.
    states will be assessed in the  exposed population compared to controls.
 IOITI ri, Y PfiO^ ES5IONAL SCHOOL INVOLVED (M,aic*l.   SIGNATURE OF PRINCIPAL INVESTIGATOR
                                        FOR OFFICE I
    SUPPORT MCTHOO i
                              TASK NO.

                                  1.2/5
PROJECT OFFICER
  Wilson B. Rigganl  Ph.D. & Jean G. French
                                                  RESPONSIBLE OHOANIi ATION

                                                   RTP,  N. C.	
      5 OK
                 76
                                Jcr YEA°? TC'ITATIVCLV
                       ASSUHiD BE.1ONO CyHHENT F.V.
         STARTING DATE
               4/76
?S7IMATtD CO^
DATE
  7/78
        5740.1 (7.72).   RCPLACrS PHS FOR
                                   M 160 AND SI-SIE 7C.A WHICH MAT NOT SE USED.
                                             141

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                   PROJECT NO. [Do nol u«r Ihiit «poco,

                                                                   5SIE
     PREPARED TOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                      CKA
TITLE OF PROJECT stu(jy the health effects from NO2, CO  and certain hydrocarbons in newly
 insulated homes
6IVE NAVES. OEPARTMLNTS. AND OFFICIAL TITLES Of PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTH6S
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
NAME ANO ADDRESS OF APPLICANT INSTITUTION
SUMMARY Of-' PROPOSED V.3RK - (I) ot>j<-v-livft. (2) Arpreaeh. (i> Current Plum [iflrt/or Pro^sus (200 words or less. OoUt confider.ti.-i1. data).
   In the Soithsoninn ^cittrcr Iltformation EKrliarisv. aumrrMrira of work in prC£T?«» arc cxchanqvd wllh (Ovctnmer.t and privat* ac#neltf> *'JP-
purlinc r«««»rch and Are forwarded to investigator* who r#Q-jesl such tn'oreution.  Your surnmary Ls to b« used for these purposts.

      The purpose of  this  task is to determine if better  insulation of homes will contribute
  to higher levels of  certain  indoolr air pollutants  with commensurate adverse health effects.
  Measurements of NC>2,  CO and certain hydrocarbons will be taken at regular intervals
  both before and after the insulation of the home.

      Biological  specimens and information on certain symptom states will also be collected
  during the  same time period.
           fc E5S ION A L. SCHOOL INVOLVED (
                                            SIGNATURE. OF PRINCIPAL INVESTIGATOR
                                         FOR OFFICE USE ONLY
350K
                76
                                                   PROJECT OFFICER
                                                   lean G,  French,  Dr. P.  H.
                                                   RESPONSIBLE ORGANIZATION
  . O*" T UTuRC YEAR? TENTATIVELY
ASSUNLD OOONO CURRENT F.Y.
                 1
STARTING DATE
    4/76
ESTIMATED COMBLETIO-.
 *T!o/78
    Form 5740-1 (7-72)    REPLACES PHS FORM 160 ANO 51-SIE 70A WHICH MAY NOT 8C USED.
                                               142

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
                                                                                 Form fyproi/ed

                                                                                O.M/3 No. HS-KOOSl
                                                    PROJECT NO. (Do not us* Ihje ipmr.f)

                                                    SSIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                            CKA
                   Installation  in CHAMP Stations  of Equipment Designed  to Provide

                             " FICIAL TITLES OF PRINCIPAL INV
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
                                                      NVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
NAME AND ADDRESS OF APPLICANT INSTITUTION
Rockwell  International Corporation - Air Monitoring  Center
SUMMARY OF PROPOSED WORK -  (I) Objective.. (2) Approach. (3) Current Plans and/or Progress (JOO words or l.n. Omit confidential dull).
   In the Smithsonian Science Information Exchange, summaries of work In progress are exchanged with government and private agencies sup-
porting research and are forwarded to Investigators who request such Information. Your summary 1* to be used for these purposes.



      The  purpose of this  task is to develop and install  automatic aerosol monitoring
Instruments  in the Community  Health Air Monitoring Program System.  This contract

was awarded  on July 1975  and  should be  completed by  July 1976.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED flUedirnf,
                                              SIGNATURE OF PRINCIPAL INVESTIGATOR
    UPPORT METHOD (CttcCH one)ITASK NO.
                                           FOR OFFICE ySE_ONLY__-	

                                                    TpROJECr OFFICER
      OBLIGATED
  $200K
  $733.5K
75
76
                                                        David Hinton
                                                     RESPONSIBLE ORGANIZATION

                                                        PSD. HERL	
                        NO. OF FUTURE YEARS TENTATIVELY
                        ASSURED BEVONO CUHRENT F.Y.
1 year
                             STARTING DATE

                                 7/1/75
ESTIMATED COMPLETION

°ATE    12/31/76
EPA Form 57«0-l (7-72)     REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                                143

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                              Form Approved
                                                                            OMB No.
                                                                   PROJECT HO. (Da not »•• Mi tp.c»;

                                                                   SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          CKA
TITLE Or PROJECT
   Development  of Sulfuric Acid Sampler - Phase I
CIVS NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

             Dr.  Robert L. Durfee - Management KEsponsiMlity
             Janes D. Barren - Project Manager & Principal  Investigator.
NAME AND ADDRESS OF APPLICANT INSTITUTION
             Versar Inc.
             6621 Electronic Drive
             Springfield, Virginia
SUMMARY OF PROPOSED WORK - (1) Ob>etl«.», (2) Approuh. (3) Cutr.nt P!»n» .ml/or Pro.r... (200 word! or [•«..  O=lt C9n/Id«ntl«l iftt).
   In th« Sraith«onl4n Sci«nc* Information Exchange, cununarica of work In pro(ri«a ar« «xch«nc«d with iov*mm«nc and privst* •(•net** «up>
portittc m«Krch «nd arc forwBrdvd Co biv«9ti(«tOT« vho r«qo«st such lA/oroutien. Yaur luramarjr La to b» uJ«d for th*a« purpo««i.
                     is a ptojram of design and developnent leading to the fabrication
        and preliminary evaluation of a sulfuric arid sanpler to be integrated with a
        Flane Photoretric Detector  (FPD) fcr the purpose of analyzing ambient sulfuric
        acid.   The major design goal  is to develop  a Sanpler (which, when coupled with
        FPD) will render the analysis of sulfuric acid free of chemical  interferences.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED
    . «tc.J
   SUPPORT METHOD (Check one)
                                                  PROJECT OFFICER
                                                            .  Lo.yno-H»a.
                                                  RESPONSIBLE ORGANIZATION
FUNDS OBLIGATED
NO. OP FUTURE Y£ARS TENTATfVELY
ASSURED SEYONO CURRENT F.Y.
STARTING DATE

   1/36/76
                                                                                 ESTIMATES COMPLETION
                                                                                 DATE
EPA Form57«0-I (7-7!)    REPLACES PHS FORM 156 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                            144

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          FOTTTI Approred
                                                                        OAlfl A'o. MS-RODS I
                                                PROJECT NO. (Da no. u,e 11:1. ,p,cc>

                                                SSIE
                                                                         CKA
 *lJ!iEJ":n^ROkECT (§) Cgmpare Pulmonary  Carcinogenicity  of Known Carcinqqens with and withoy
 Added Airborne Respirable Particles  (b)  Evaluate  tne Influence of Added Gases & I-LSO. Mi
 GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTrfefl '
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Professor Sidney Laskin
 (914) 351-2300
 NAME AND AOORESS OF APPLICANT INSTITUTION
 Department of Environmental  Medicine,  New York University
 550 First  Avenue
 New York,  New York   10016
 SUMMARY OF PROPOSED WORK -  (I) Objectives. (3) Approach. (3) Current Plans .nil/or Progress (200 words of less. Omit confidential data).
   In the Smithsonian Science Information Kxchaircj

 Dept.  of  Environmental  Medicine, NYU
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
    SUPPORT METHOD CCI.oi-k ime>   LTA^K No-
                                       FOR OFFICE USE ONLY
                                               TF-ROJECT O
                                                      David L.  Coffin
 •$52K
"S165K
76
76A   :'p,
" i
	 1 4 A
1

RESPONSIGLE ORGANIZATION
. Biomedical Research Branch, CSD, HERU RTF
NO. OF FUTURC YEAH? TENTATIVELY
ASSJRtD BEYOND CURRENT r.Y,
2
STARTING DATE
7/75
ESTIMATED COMPLETION
DATE
.S/25/77
                       'LACES PHS FORM 1C6 AND SI-SIE 76A WHICH MAY NOT BE UStTD.
                                                145

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             NOTICE OK RESEARCH PROJECT
  PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                          PMOJfcCT NO. ,'i>o not us* llii
                                                               CKA
       _0pveloprcent of Bio-Indicators of NO?  and SO? Exposure
I NAMES. UtPAl! r:.lt:iT5. AriO OFFICIAL TITl.tS OF PRINCIPAL INVESTIGATORS OH PROJECT OIHECTOH5 AND ALL OTHtR
t-'KsstOfiAi. rr.r<:cN:.s:L EMC.A:-Ha IN THE PROJECT.                        -      .    .    /.,.   ,     A\
:ss  H. Col linger, Ph.D., Princ. Invest., Associate Foundation Scientist  (Biocniin-iSi.;
;han D.  Greane, Ph.D., Co-Investigator, Associate Foundation Scientist-^Iir.tKino'lcgist}
ly  M. Gause, M.S., Co-Investigator, Associate Foundation Scientist  (Biochemist)
:herine  J.  Rowlands, C.-S./H.T., Co-Invastigator, Research Scientist  (Ehdocrir.ologist)
£ AMD AOUHKS3 OF APPLICANT INSTITUTION
         of Environmental Sciences, Southv.'sst Foundation for Research  and Education
I.  Box 28147 (8848 Uest Commerce Street),  San Antonio, Texas 78284
•4ARY OF PROPOSED WORK - {!) Objcclives, (2) Approach. (2) Currnc PUna anJ/or Pro.-.rsas (500 wards 07 !**». Omit confidential date).
r>i research ;trict j!r« format vied co inv;;,cJ£ator» who request such information. Your summary is to b* used for choe purposes.
 As  a result of the energy requirements  in  the United States, the oxides  of sulfur
 nitrogen will  continue to constitute  a  potential health hazard,  particularly in se-
 ted  portions of the population.  Unlike  many  toxic or potentially toxic substances,
 re does not exist at the present time  a  ir.eans' of assessing the "level of these two
 lutants. that an individual has accumulated,   It is, therefore, the  intention of this
 earch effort to examine the biochemical  action of N02 and S02 on  both lung metabolism
 nietabol•• sm in  general and develop  alterations that occur into a  type of  dose-re-
use  bio-indicator.

 The first phase of this study will  concentrate heavily on S02 and  NOj  produced alter-
 o;is  in  the chemistry end biochemistry  of lipids and proteins.   The  second phase will
 centrate on-stress-induced and/or direct chemical insult-induced  release  of specific
 ^active compounds.   Specific measurements will include oxide-induced changes in lung
 serum; 1) lipids (peroxides, prostaglandins, lipolysis, etc.);   2) proteins (SOg
 N02 interactions producing electrophoretically detectable changes);  3)  immune re-
 nses (S02/ti02 induced specificity);  and   4) stress hormones (histaraine, serotonin,
 echolomines, bradykinins, ACTH).

 Starting with  acute and chronic exposures, a specific detectable change  or a series
 detectable changes will be investigated  in  regard to its or their usefulness,over
 ying periods of exposure time  and  bracketing 0.14 ppm S0£ and 0.13 ppm MO?, as
 od/urine bio-indicator tests.
TIFY PROFESSIONAL SCHOOL INVOLVED (M^dic^l
1. ftf.)
earch Foundation
S'GNATuatOF PBJNC
IPAL INVESTIGATOR
Q&—^>
DATE
March 10, 1976
FOR OFFICE USE ONLY w
UPPOflT 1-irTMOO rCVcfr on,-)
AOtNCY ST. KP .-;,„,.„„,„„
H.-.-.shr^r""'""^1 	
TASK NO.
A A


PROJECT OFFICER,.
RESPONSIBLE ORGANIZ ATJON 	 	 ""
HERL,. RTF
IS OSLir.ATCO F.Y. NS. OF FL'TUPE. Y!T •••"', TE'i 7a-l VELV
	 , ASSURriU :JFYOMO CURRSVT F Y
®?f > i b 7 6 1
STARTING DATE
ESTIMATED COMPLETION
DATE ,
2/26/79
 -rt.*i 57(0-] (7-7JJ
                     t'£ PMS FOR1-' !5'j AND SI-SIS. 7GA WHICH MAY HOT f:C USED.
                                        146

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              U.S. HNVIHOHMEN I At. t'ROICCTIOM
                NOTICE OF RESEARCH PROJECT
                                              PROJECT NO. (
                                              '.'.If
          niiO FOR IMF SMIIHSONIAN SCICHCE INFORMATION EXCHANGE
                                                                  CKA-
TIILE OK PROJECT
                Procurement  and Characterization of Refined  Particles
GIVF MAMr S. DCPARTMF UTS. ANO OFFICIAL Tit LES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PEnsONNEL.CI'CACEO IN THE PROJECT.
Earl 0.  Knutson, Ph.D.
Research Scientist, Fine  Particle Division
NAMC AflU ADOfttSS OF APPLICANT I N't T I T If 1 ION
Illinois  Institute of Technology Research
10 West 35th Street
Chicago,  Illinois  60616
SUMMAMV OF PROPOSED WO"K -  (I) (>l.ti-i livr*.  Aprrr>.->r'lt. (.11 Ciirrriil I'l.Ht, itml/i* I'M-KM-X* (?t>O.warw^ who rrq'tf SI lurh infofmull4M.  VQI^- xuimnafy Is lo bv usrd tor these f»uxpo»es.

     The objective of  this contract  is  to obtain a variety  of pure participate sub-
stances, whose size  distribution  is  reliably and carefully  characterized, and when
necessary reduced, for use in a variety of biologic experiments.   The experimental
protocols will employ  participate suspensions for intratracheal instillations in
small animals, for inhalation exposures of animals to  aerosols of these substances
and administration of  particles to in  vitro cell culture  systems.  In addition, a
limited  number of different preparations of selected,  finely  parti'culate metal
compounds in combination with the polycyclic hydrocarbon  carcinogen benzo(a)
pyrene are required  for intratracheal  administrations.  These various preparations
will be  used by  several  different investigators supported by  EPA contracts, as
well as  fay in-house  investigators at ERf-RTP

     This contract is  designed to provide a centralized,  highly qualified,  uniform
source for particle  preparation and-characterization.  This will  help eliminate
one potential cause  of factitious variability between  different investigations
seeking  to contraiu  biologic consequences of environmental  toxicants.  The  specific
compounds of interest:  platinum-metal  or its oxides,  palladium metal and its oxide,
oxides of lead",'  fiickel, cadmium,  manganese, copper and zinc.
 lit Hilly I'HOI E.SSIONAL SCHOOL INVOLVED /rtl
 tfiilal, ftc.t

 Private Research  Institute
                                         StCNATUNfOf
   SUr*l*OMT MCTllOO f flip I'll     TASK MO,
                    	

                    =2	1       4 B
 L.
                                      fOROFFICE; USE .ONLY
                                               PROJECT OFFICER
                                Chpudari Unmnineni.  D.V.M.. Ph.D.	
                              "SPONSIDL ^ORGANIZATION
                                Biomedical Research_Bram:h, CSD, HERtRTP_
     OPLIOATEO  F.v.
     $70K
76
                      MO. Or I II mill. VI.AHS 1 t'HAIIVELY
                      ASSURED BEYONO CURRENT F.Y.
                                                        STARTING OATT
                                                            7/75
                                                                           tSriMATEU CUM*'l_l T'QN
                                                                                 6/77
 »A Fo,» 5740-1 (7-7J)    REPLACES PM5 FORM IM AND SI-SIE 76A WHICH MAY NOT OE USED.
                                               147

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              U.S. ENVtRONMt-MTAL PKOT CCTICM AGENCY
               NOTICE OF RESEARCH PROJECT
                                                                       t-arm
                                                                     cum .VD.
                                                             PROJECT MO. {Da ,
                                                             ssie
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                              CKA
TITLE OF F'HOjECTjdentificat;ion and Measurement of High Molecular Weight Organic
    Etuis
GIVE NAMES, DEPARTMENTS. At
PROFESSIONAL PERSONNEL ENGAGED IH THE PROJECT.
                                                      TORS OR PROJECT DIRECTORS AND ALL OTHER
 Physical Chemistry Division,  Principal Investigator,  Edward B. Dismukes, Head, Physical
 Chemistry Section; Herbert C. Miller,  Research Chemist; Walter R.  Dickson,  Research
 Chemist; Ruby H. James,  Research Chemist
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Southern Research Institute,  2000 Ninth Avenue South, Birmingham, Alabama 35205
SUMMARY OF PROPOSED V.OPK - il) Objrftivci, (2) Approach, (3) Current Plans und/or Progress i200 » ords or ]••*. Otnit con/idpr.ti,i: data).


     The objectives of this project are to develop methods and procedures to identify and
 measure the organic  compounds emitted to the atmosphere from energy-related  sources and
 to determine by means of bioassays what fractions or classes of the organic emissions are
 of potential lexicological  significance.  The experimental work  involves the development
 of sampling methods for the quantitative collection of organic emissions from coal-burning
 power plants and ail refineries; the use of separation techniques for classifying types of
 organic compounds and isolating  individual compounds; identification of individual com-
 pounds  by gas chromatographic, mass spectrometric,  and other  methods; and the screening
 of isolated fractions for toxicity by tissue-culture methods.
ILHNTIFY PKOf CSSIONAL SCHOOL IN VO L VED f.W
d.-,ii..f. .-re. I
SIGNATURE OF PRINCIPAL INVESTIGATOR

  William Barrett
DATE

12/23/75
                                     FOR OFFICE USE Or;LY
 U'iOC COLIGATFD
               76
                                             PROJECT OFFICER
                                              David L. Coffin, D.V.M.
                                             RESPONSIBLE ORGANIZATION
                     NO. Of FuT.J^C YEAP5 TCNTATIVCLY
                     ASSUhLD acroNO CURRENT F.V.
                                              HERL, Clinical Studies Division, RTF
                                                      STARTING DATE
                                                           11/75
                                      9/78
EPA Fom 5740-1 (7-72)    RL'PLACF.S PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BC USED.
                                        148

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                       OMB No. 138-R0081
                                                              PROJECT NO. (Do ml u«..M,l. .p,c.)

                                                              SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                               EPA~
                                                                   CKA
 riTLE OF PROJECT
 In Vitro Screening  of Selected Air  Pollutants for  Potential Cardnogenlcity
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Dr. Michael D. Waters, Research Chemist, BRB, CSD,  HERL
 Dr. Leonard Schrechtman, Microbiological Associates
NAME ANO ADDRESS OF APPLICANT INSTITUTION
 Microbiological Associates, Inc.
 Bethesda, Maryland
SUMMARY OF PROPOSED »OHK - (|) Objrctlven. (2) Approach, (3) Current Plan, ind/or Pro
-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                       O.MB No. DS-R008I
                                                              PROJECT NO. fOo net u«« rftfa mftmc*)

                                                              SSIC
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                    CKA
TITLE OF PROJECT in \t^ro Screening of  Selected Air Pollutants for Potential
Carr.inogenlHty Iking Microhial "wst.pini (Phase 4)	
GIVE NAMES. DEPARTMENTS. AMD OFFICIAL TITLES OF PRINCIPAL INVESTIGAT
                                                      A TORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Dr.  Michael D. Waters, Research Chemist, BRB, CSD,  HERL
NAME AND ADDRESS OF APPLICANT INSTITUTION

 To be awarded  (negotiations 1n progress)
SUMMARY OF PROPOSED WORK - lr.l
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
   SUPPORT METHOD (CltrrJk <»•,->
FUNDS OBLJGATEO | F.Y.

  $110K       76A

  $30K        76
                                      FOR OFFICE USE ONLY
                                  4C
                                               PROJECT OFFICER

                                                Dr. Michael  ET.
                     NO. OF FUTURE YEARS TENTATIVELY
                     ASSURED BEYOND CURRENT F.Y.

                                  1
                                               RESPONSIBLE ORGANIZATION

                                                Eivironmental  prot.ect.inn Agency"
     STARTING DATE


           11/75
ESTIMATED COMPLETION
DATE

  10/77
                     'LACES PHS FORM 166 AND SI-S1E 7SA WHICH MAY NOT SE USED..
                                         150

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PROJ
                                                                              Form- Approved
                                                                            OAlfl No.  I5S-ROOSI
                                                                  PROJECT NO. (Da not use Oil, tpacej

                                                                  SSIE
              T Detennination of the Influence of Mineral  Cofactors in  Conjunction
             	with  rarrinngpn<: frnm Fnorny RplatPd Mat.pr-ials	\	
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Northrop Services
NAME AND ADDRESS OF APPLICANT INSTITUTION

 Huntsvilie,  Alabama
SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach. (3) Current Plons and/or Progress (200 words or lass. Omtt confidential data).
   In the Smithsonian Science Information Eschew*, summaries of wort in progress ere exchanged with government and private agencies sup-
perllnc research and ars forwarded to Investigators who request such Information. Your summary Is to be used for these purposes.

       Determination of-the influence of environmental  materials such  as fibrous
  amphiboles, fine  particles and  the like as cofactors  with carcinogenesis influences
  from alternate energy  sources such as  coal gasification and  liquefaction,  shale
  oil products and  effluents.   The methods employed would be intratracheal instillation
  and intrapleural  innoculation.   The endpoints would be formation of  cancer in  the
  lung or pleura or development of precancerous lesions compared to  appropriate
  controls.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Mcdltol.
                                            SIGNATURE OF PRINCIPAL INVESTIGATOR
                                         FOR OFFICE USE ONLY
   SUPPOHT METHOD fCl.cc* on.-)
                                                 [PROJECT OFFICF.R
                                                   Dr. David L. Coffin
                                     4D
                                                 RESPONSIBLE ORGANIZATION

                                                  CSD, HERL 	
FUNC"= 1SLIOATED | F.Y.
$300K
                 75
                 76
                        NO. OP FUIUHL VCA?
-------
U.S. ENVIRONMENTAL PROTECTION AGENCY
NOTICE OF RESEARCH PROJECT
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
Form Approved
O.H8 No. D8-R0081
PROJECT NO. (Da not tie* Ih/s ,p.c»;
SSIE
EPA
CKA
TITLE OF PROJECT Compare Affects of Rosplrable Particles, Gases and Mists Using
'MTlf'll Airwau Rocicrani-o -in [Wil/m/c ae tha MnHol fnr Dtilmnnar-u Tr-K-r-1 taf Inn
GIVE NAMES
DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AHO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT,
 Dr. Donald  E.  Gardner, Chief,  BRB,  CSD, HERL
 Dr. Morton  Lippman, Professor,  Environmental Medicine, NYU
NAME AND ADDRESS OF APPLICANT INSTITUTION
 New York University
 Institute of Environmental Medicine
 Sterlina Forest.  New York       	
SUMMARY OF PROPOSED WORK -  Srnltlisonino Science Information ExchanRc, summaries of work In progress are exchanged with government and private agenclea sup-
pnnlnft rrararch »nd ar* forwardrd to investigator* who request such information. Your eumnwry t« to be uaed for theae purpoaaa.

      The  Investigations of the effects  of (NHJ-SIL and HjSO,, aerosols on pulmonary
 function, regional  deposition, and  bronchial clearance  wul be continued 1n order
 to clearly  establish  the nature  of  the  effects produced and their dose-response
 relationships.  This  will  provide a sound  basis for subsequent tests  with the same
 aerosols  on human  volunteers.

      Airway resistance, dynamic  compliance, and regional  particle deposition were
 selected  as sensitive Indicators of physiological response.  They will  Indicate
 transient effects  attributable to the Inhalation of airborne irritants  at levels
 which produce  no pathological effects.   Effects on these physiological  functions
 in donkeys  should  be  essentially similar to those produced by the same Irritants
 in humans.  A  major purpose is therefore to clarify the dose-response relationship
 for pulmonary  irritation resulting  from transient elevations In the ambient
 pollution aerosol  concentration.              '

      The  intrabronchial deposition  patterns of (NHJ2S04 and H?S(L aerosols will
 also be measured 1n hollow bronchial casts of donkeys and human airways.   The rate
 of water  vapor  concentration on aerosol  growth and subsequent deposition  1n hollow
 casts will  be  tested  in order to evaluate  mathematical  predictions of droplet
 growth from physico-chemical factors.
IDENTIFY PHOFESSIONAL SCHOOL INVOLVED (Mrtltf.tl,
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD r
                                 4E
FUNDS OBLIGATED
 $70K
 $70K
 $270K
                                              PROJECT OFFICER

                                                D
                                                                               .  ,J(
               75
               76
                                                        6-20-76
                                                                .Aftect1on A
                                                                          \°
                          PM$ FORM 166 AND SI-SIE 7SA WHICH MAY NOT 9E USED.
                                        152

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                                        INltKIM
              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                       o.\\n NO. ns-Raosi
                                               PROJECT NO. (Dor

                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                       CKA
TITLE OF PROJECT Development and application of automated  screening methodology  for
evaluating mfiriifi ration by candidate  pollutants of  patterned hehavinr in primates.
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
NAME AND ADDRESS OF APPLICANT INSTITUTION
                                        Dr.  William Buck
                                        Iowa State University
                                        125  Beardshear Hall
                                        Ames,  Iowa   50010
SUMMARY OF PROPOSED WORK -  (1) Objectives. (J) Approach, (3) Current Ploiis «nd/or Progress (200 word, or leu. Omll conddtnll.l d.tn).
porting
      Coal utilization and conversion products contain  many compounds which affect  the
 central nervous  system'(i.e., organometallics, hydrocarbons,  etc.).  The neurobiological
 effects of these compounds in primates will provide  valuable  data for regulatory
 decision making.  This task calls  for the development  of testing procedures  to  study
 the effects of  coal  products on  spontaneous behavior and to develop computer programs
 to define the various motor items  comprising this spontaneous activity.  Specifically,
 the testing system will be automated to provide computer identification and  analysis
 of the monkey's  patterned behavior utilizing pattern recognition techniques.  Since
 the animal's behavioral output  is  a composite of nervous system activity, careful
 analysis of this behavior should provide a measure of  subtle  changes on nervous system
 function brought about by exposure to coal products.  Once developed, the testing
 system will be  evaluated as to  its efficiency in detecting changes in behavior  by  the
 administration  of pharmacological  agents.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Mcilieal,
l/CMUll. etc.')
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
   SUPPORT METHOD f
=P~
                                      FOR OFFICE USE ONLY
                                  4 F
                                PROJECT OFFICER
                                Lawrence W.  Reiter
FiiNrr, "OBLIGATED 'F.Y.INC. OF FuTURr YEAHJ TENTATIVELY
                                lESPONSIBLEOHGANIZATIO-  ^-.Q

                                Research  Triangle Pnrk. NC
$285.5K
$  33.OK
75
76A
                     I ASSURED BEYOND CURRENT F.Y.
                               STARTING DATE

                                   1/75
ESTIMATED COMPUE;I ION
DATE
        7/29/78
EPA f I,,,- W'l 7-7J?    RCPLACES PHS FORM 166 1ND SI-SIE 7SA WHICH MAY NOT BE USED.
                                             153

-------
U.S. ENVIRONMENTAL PROTECTION AGENCY
NOTICE OF RESEARCH PROJECT
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PROJECT Evaiuate the Influence of Inhalation of Acic
HMO., anri Partirles on Production of Chronic Lung Disease 1
GIVE ifAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR 1
Form Approved
OMD No. HS-KOOSI
PROJECT NO. (Do not u» l*la .pec.)
S5IE
EPA
CKA
Aerosols, H,bu., iu,,
n Rats, Guinea Pigs 8 Primate
"ROJECT DIRECTORS AND ALL OTHER
 Dr. Donald E. Gardner,  Chief, BRB, CSD, HERL
 Dr. Walter Tyler,  Director, Primate Center
NAME AND ADDRESS OF APPLICANT INSTITUTION
 University of  California, Primate Center
 School of Veterinary Medicine
 Davis. California	.     	
SUMMARY OF PROPOSED *OHK - (I) Objective*. (2) Approach, (3) Currint Plana and/or Profreia (300 word* or !«••. Omit confidential data).
  In Ihr SmlthMonlnn Scicncr Information Exchange, summariea of work In progreaa ara enchanted with covernmant and prlvata afanclea sup-
porting research and tare forwarded lo investtgatora who requett auch InfoematIon. Your autninary la to ba na«d for thaaa pivpoaaa.

      The effects  of acid sulfur oxtde  aerosols  will  be studied 1n rats, guinea pigs,
 and nonhutnan primates.   Major variables which will  be considered  Include (1) biology
 of the respiratory  system of the experimental animal  when compared to  that of man,
 (2) concentration of the acid mist,  (3) size  of the  particles In  the add mist,
 (4) duration of exposure.  Interrelationships of the latter three factors will be
 considered 1n experimental design.   Initial studies  will utilize  specific pathogen-
 free rats, while  later  studies will  utilize nonhuman primates.  Concentrations 1n
 initial studies will  be higher than  ambient 1n  order to permit location of effects
 in the respiratory  system resulting  from carefully  controlled particle size
 droplets.  Stable,  reproducible, monodlsperse sulfuric acid aerosols 1n sizes ranging
 from 0.3 to  5 vm  are needed to study the site and particle size response in animal
 inhalation studies.

      Results will be evaluated using physiological,  morphological, and biochemical
 techniques.  Clearance  gf airways will be  evaluated  using tantalum bronchography
 and inhalation of radiolabelled particles  followed with an Anger camera.  Morphologica
 evaluation will include use of light,  transmission electron, and  scanning electron
 microscopy,  histochemistry, and autoradiography.  Biochemical techniques will be
 used to study the rate  and pattern of  synthesis of  glycoproteins.

      Macaque monkeys will be employed  for  the purpose of validating  the data from
 rats in a species phylogenically and anatomically closer to man and  to approach the
 problem of pulmonary physiological studies on a larger species using more refined
 methods.
IDENTIFY PRortislONAL SCHOOL INVOLVED fMi-i//c.<;. SIGN
Veterinary
ATURE OF PRINCIPAL INVESTIGATOR
DATE
FOR OFFICE USE ONLY
SUPPORT METHOD [Otr.-A on.-l

x





FUNOS OBLIGATED 1 F.Y. NO. C
$100K 74 "SU
$100K 75
TASK NO.

4F

PROJECT OFFICER
Dr. DonalH F. fiarrtnpr
RESPONSIBLE ORGANIZATION Jflf/ f- '
Environmental Protection Aaencu HERT. RTP
F FUTURE YEARS TENTATIVELY
RED BEYOND CURRENT F.Y.
STARTING DATE
7-1-76
ESTIMATED COMPLETION
DATE
6/77
$120K 76 --*CES PHS FORM 166 AND SI-5IE 76A WHICH MAY NOT BE USED. '
$120K 76A
                                     \ 154

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                           Perm Approved
                                                                          OMB No. 1}S-ROOS1
                                                 PROJECT NO. fOo not ueo Hlfe spacej

                                                 SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                 EPA~
                                                                    CKA
TtTLEOF
         ROJECT  .Evaluate Effects of  Chronic or  Intermittent Exposure  to
             PartirlPS and-Mlsts l,l?inn Mp'.IT'? Pulmonary Infgctivity Morl*?1	
             ARTMENTS. AMD OFFICIAL TITLES oTpRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
GIVE NAMES. OEP
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Dr. Donald E. Gardner, Chief, BRB,  CSD, HERL
 Dr. Richard Ehrlich, IIT  Research Institute
NAME ANO ADDRESS OF APPLICANT INSTITUTION

 IIT Research Institute,  Life Science Research  Division
 10 West  35th Street
 rhipann   TTMnrvU fiflfilfi	
SUMMARY OF PROPOSED WORK - (I) Objeclivee. (I) Approach. 
FUNDS OBLIGATED
 $70K
 $70K
 $90K
 74
 75
76
                                    4G
                                                 PROJECT OFFICER
                                                   Dr.  Donald  E.  Gardner
       NO. OF FUTURE YEARS TENTATIVELY
       ASSURED BEYOND CURRENT F.Y.
                                                 RESPONSIBLE ORGANIZATION

                                                  £0¥4jWMienta1  Protection-Anene.»  HFRT, RTF
STARTING DATE

 8/75
                                                              Agency, HERT., RTF
                                                              ESTIMATED COMPLETION
6/2/77
                          rs PHS FORM 166 ANOSI-SIE 76A WHICH MAY NOT BE USED.
                                            155

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                        OMB No.
                                                               PROJECT HO. (Do not »•• rfilt «paca>

                                                               551E
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                   CKA
TITLE OF PROJECT
 Scanning Electron Microscopic Examination  of the Effects  of Air Pollutants on  Pulmonary
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHERSySt( ftlS
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Dr.  Donald  E.  Gardner, Chief,  BRB.CSD.HERL
 Dr.  Michael  D.  Waters, Research Chemist,  BRB.CSD.HERL
 Ms.  Catherine  Aranyi, Research Biochemist, IIT Research  Institute
 Dr.  James Fenters, Scientific  Advisor,  IIT Research  Institute
NAME AND ADDRESS OF APPLICANT INSTITUTION
 IIT Research  Institute, Life  Sciences Research Division
 10 West 35th  St.
 Chicago,
is  60616
SUMMAHVoV PROPOSED'WORK""!) Objectives. (2) Approach, (3) Currant Plan, and/or Proireai (200 void* or leaa. Omit confidential data).
   In thr Smilhsoninn Science Information Exchange, summaries ot work in proarc** are exchanged with government and private agancjaa pup-
porting research Bid tire forwarded to invesligalara who requeat auch Information, Your luminary la to be uaed for theaa purpoaaa.
      The objective of this  study is to  correlate the in  vitro toxicity  of selected
 metal oxides  with such physical characteristics of the particles as surface area,
 size, shape,  and density.   The investigation is directed toward resolving whether
 the toxicity  of a test compound is affected by (a) adsorption to carrier particles
 having large  surface areas  and (b) the  shape and size of the carrier  particle.
      Rabbit alveolar macrophages (AM) will  be exposed in vitro to those particle
 concentrations  (of PbO-,  Mnop-, NiO-, and  CdO- coated and  uncoated fly  ash) established
 in the experiments concluded  to date which  produce a decrease in viability to 50%
 after 21 hours  of incubation  at 37°C and  follow the time course of the  changes in
 viability and enzyme release.   In addition,  SEM examination of AM with  engulfed
 particles at  various periods  during incubation will be performed.  The  purpose is to
 map elemental distribution  within the image, so that one can locate the test element
!in the cell and determine whether and to what extent it  is  still confined to the
 surface of the  particle,  or if it has been  solubilized by  the cellular  enzymes and
 where it is located within  the cellular structure.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED lM,;ti<;
-------
               U,S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approvrtl
                                                                       OMB No.
PROJECT NO. (Do no. 
-------
U.S. ENVIRONMENTAL PROTECTION AGENCY
NOTICE OF RESEARCH PROJECT

PREPARED
FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
rnrm Afipravrd
OA1B No. 158-ROORI
PROJECT NO. (Do not <»• Hilt >p«»J
SSIE
CKA
TITLE OF PROJECT cytotoxicHy Evaluation of Selected Sulfates and of source
and Amh1f?nt..Aii:-Samnlfis, 	 	
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

Dr. Joellen L.  Hulslngh, Research  Chemist, BRB, CSO,  HERL
Mr. James  A.  Campbell, Northrop Services, Inc.
NAME AND ADDRESS OF APPLICANT INSTITUTION
Northrop Services, Inc.
P.  0.  Box 1484
Huntsville. Alabama 35807	
SUMMARY OF PROPOSED WORK - (]} Objrrllvra. (2) Approach, (3) Current Plan* and/or Prop**! (200 word* or (•••. Omit confidential datt-
  In (hr Smith* on inn Science Infurrmttlon Eichange, • ummarieB of work In progrcia «r« exchanged with government and prlvmtm mtmncif* cup-
porting r«»iirch and ur« forwarded to lnve«lig*lor» who r*qu#»l »uch Information. Your • urnmvr 1« to b* iuvd for th»« purpoi**.

      The objective of this task 1s  to determine the  relative cellular toxlclty of
selected compounds Including  inorganic metallic chlorides,  sulfates, sulfftes  and
other pure  chemicals and crude  samples obtained from stationary sources and
ambient air-

      Animal and human cells of  pulmonary origin (i.e.  rabbit alveolar macrophage and
Strain  UI-38 human lung fibroblasts)  will  be cultured  in  vitro and exposed  to  the
agents  listed above.  Cellular  integrity and function  wTll  be monitored by  measure-
ment  of viability, cell numbers, phagocytlc activity,  ATP and where applicable
synthesis of DNA, RNA and protein.

      Immediate objectives of  this program are to:

      1.   Determine comparative  toxlclty of metallic  sulfates  and chlorides.   Initial
          studies  with rabbit  alveolar macrophages Indicate  the toxicity is  similar
          for the  sulfates and corresponding chlorides  of  Zn,  Mn, Ni, Cu,  Cd, Hg and V-

      2.   Assess the significance of trace  metal interactions  in evaluating  the
          toxicity of crude environmental  samples.  Initially  interactions which affect
          toxicity have been observed  between V and Cu, Cd and Se, Hg and  Se.

      3.   Assess  the effect of the bisulfite ion (Including  ammonium bisulfite)
          on the toxicity of trace metals.

      4.   Assess  the toxicity  of source and ambient air samples.
IDENTIFY PROFESSIONAL SCHOOL IN VOL VEO fMvf/r.i/,
SIGNATURE OF PRINCIPAL INVESTIGATOR
DATE
FOR OFFICE USE ONLY
SUPPORT METHOD (Oi,-,-t  TASK NO.

X

FUN
$4!
$4C
'sic
' 1

RESEARCH GRANT

PROJECT OFFICER
Dr. Joellen L. Huisingh
RESPONSIBLE ORGANIZATION
Environmental Protection Aapnr.v, HERL, RTF
05 OSLICATFO IF Y. 1 NO. OF FUTURE YEARS TENTATIVELY
V 7A ASSURED BEYOND CURRENT F.Y.
£ 75 Continuing
OK 76 PLACES PM5 FORM 166 AND
STARTING DATE
ESTIMATED COMPUET'
DATE
9/76
St-SIE 76* WHICH MAY NOT BE USED-
                                     158

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                              Form Approved
                                                                                 o. 118-R0081
                                           PROJECT MO. (Da not u» Mm space.)

                                           5SIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                     CKA
TITLE OF PROJECT Establishment of  a. chemical repository tor alternate energy source
  ftvr-tal  fnr fcov
-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                            Form Approved
                                                                          OMB No. lia-ROOBl
                                                                 PROJECT NO. (Do not uae tfiie apacej

                                                                 SSIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                       CKA
TITLE OF PROJECT    nitect or  alternate  energy source material on wnoie animal
carcinogenesis by percutaneous application of  extracts  and fractions to mice
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Principal Investigator:  Robert Wood
NAME AND ADDRESS OF APPLICANT INSTITUTION
EROA
Oak Ridge, Tennessee
SUMMARY OF PROPOSED WORK -  (I) Objective, (2) Approach. (3) Current Plani and/or Progros (200 war A, or le.t. Omit confidential data).
   [n the Smithsonian Sclenca Information Exchange, BUmmarlea of work in progreaa are exchanged with government and private aajenelea aup-
portlng research and are forwarded to Investigators who request such information. Your summary la to be used for theae purpoaea.
   This project constitutes the lead  laboratory for carcinogenesis  for the  EPA studies
of the  toxic effects of products and  effluents from alternate energy sources.

   Materials for study will be derived through the chemical repository.  Materials
received will be subjected to preliminary toxicity testing  and fractionation
followed by cancer screening by standard methods,  including skin painting and injection.

   Data from this  contract will be  used to evaluate data  from other methods such as
bacterial mutagenesis, neoplastic transformation,  intratracheal instillation, etc., in
order to arrive at a coherent view  of the relative value  of various methods in dealing
with practicable evaluation of carcinogenesis  potential of  crude materials  or portions.
                       OL INVOLVED rMrxftcnf,
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
In_teragency_Agreement
   SUPPORT METHOD (Check tine)
                                        FOR OFFICE USE ONLY
                                    4 I
                                                 PROJECT OFFICER
                                                  David L. Coffin, D.V.M.
                                                 RESPONSIBLE ORGANIZATION

                                                  OP. HERL, RTF
FUNDS OBLIGATED
$100K
S190K
F.Y.
 75
 76A
                       NO. OF FUTURE YEARS TENTATIVELY
                       ASSURED BEYOND CURRENT F.Y.
                                  1
                                                          STARTING DATE
9/76
                 ESTIMATED COMPLETION
                 DATE
9/78
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 16$ AND SI-SIE 76A WHICH MAY NOT BE USED.
                                             160

-------
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          ray* -nppn,
                                                                          nii ,Vf,.
                                                                PROJtCT NO, ffto nut

                                                                5SIE
                                                                   CKA
T.TLEOF I'NOJECT  Deve 1 opment  of Methods for Determination of  Potential  Carcinogenicity in
Neoplastic Transformation  System Emp1oyinn._Crude Material  from Alternate Energy Sources
GIVE NAMES. DEPARTMENTS,  ANO OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OB PROJECT DIRECTORS »NO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT,

Principal  Investigator:  To be named.
NAME AND ADDRESS OF APPLICANT INSTITUTION

 (To be awarded  - negotiations in  progress.)
SUMMARY OF PROPOSED WORK - (I) ol.j,-, I i»r». (2) Apnroiu-h. (3) Cnrtcnl Plans unil/ui I'tur.mi |IOO' »or,li or In.. Omll cui.lMrnli»t dim).
   In Ihi- Smillmujiiiin Si-iriirr luf <,rm;il i..n L:mi-li»iH;r. •uRimartv* at wnfk in pr.,,;rvb« urc r» liulif.c-I wUb K»'>-rtir»rnl iHKl |iriv;,lf .,Krnrlc» sut>-


      This effort constitutes Phase  3 of the  contract, "In Vitro  Screening of  Selected
Air Pollutants  for Potential.  .Carcinogenicity."   The objective of this contract  is to
experimentally  assess the validity  of current methods for introducing crude samples
(as derived  from alternate energy sources  such  as coal gasification  and liquefaction)
into neoplastic cellular transformation systems.  The contractor will examine the
solubility of  such crude samples or fractions thereof in the conventional solvents
such as acetone, benzene or dimethylsulfoxide and in new solvents to be selected by
the contractor.  The  contractor  will study the  influence of  the  solvent systems
employed on  the morphological  and tumorigenic transformation using the  test systems
developed in Phases  1 and 2.*"1
lOCNIirv 1'HIVFLSSIOHAI. ii.IIDOL INVOLVtO I.W.-./M..I.
                                          SIGNATUHL OF HHINCIHAL INVCS1 IC.AT OH
   SUPPORT METHOD fOn-cJi utt.-t
                                     _FOR OFFICE USE ONLY
                             TASK MO.             | PROJECT OFFICER
                                                        _0._Waters, PhJ).	
                                                RESPONSIBLE OUGANIJ ATION
	—	      ""  4J         I RESPONSIBLE OUGANIJATION
JL -^if.lllI12.1?-I"iiI	                     HERL, CSD,_Bioredic_a_l__Re_search_Bra_nclVRTp

^oSS--j^-yNf^~                       i^O-iV*        gi^T-JoCO.^,,
     $60K

                  76
                                                                11/75
                                                                                    10/76
EPAF.,m57«0.|(;-72)    RtPLAClS Pi,* ,-OKM „.,. .NO M-sic «	;MM.THOIM, ,m l
                                               161

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               U.S. ENVIRONMENTAL PhOl ECTICTI AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                           f-'tifm ApfUH-fJ
                                                                         OHfl \a MS-ffWS f
                                                                PROJECT MO. f/?o nuf use rh»« tpacft

                                                                5SIE
     PREPARED TOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                 CKA
TITLE OF PROJECT Determination of Toxicity from Coal Gasification Products Using Cellular
OIVE NAMES. OEPARTMLNTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Dr. Arion Zarkower, Associate Professor of Veterinary Science,  Dept.-of Veterniary Science,
College of Agriculture
NAME AND ADDRESS Or APPLICANT INSTITUTION
Pennsylvania  State University, 115 Animal Industries,  University Park,  Pennsylvania 16802
SUMMARY OF PROPOSED WORK - <]> Objfftii-i's. (2) Approach. (3) Current Pljns and
   In the Smithsonian Science Infornu*:— r._u—,
putting research and are forwarded to
                        <]) Obj«.*-tlws. (2) Approach. (3) Current Pljns and/or Prog;e»s i200 worjs or less. Omit confident!*: dam).
                        union Exchange. summaries of work if, prepress are exchanged with government and private agencies sup-
                        ' investigators who request such information.  Your summary is lo be used for these purposes.
    There is the potential that the  present energy crisis  may lead to a rapid proliferation
of industrial plants which will convert coal into.gas.  It is therefore possible that one  or
more of the various coal gasification procedures may lead to the release of a highly toxic
gas, arsine.  The purpose of this contract is to evaluate the potential environmental
hazard of this-substance.  In general, the specific  aims are to: 1)  determine the mechanism
of arsine-induced damage to human red blood cells  in vitro ,  and 2) to ascertain whether '
arsine interferes with DNA repair processes in  ultraviolet-irradiated E.coli and in mammalia
tissue culture cell lines.   The approaches chosen for this study are based on two assumptioi
that it is necessary to know the acute mechanism of toxicity of this agent  in order to
understand its' implication to human health,  and that the possible relation  of arsine to
carcinogenesis requires at least preliminary assessment.
lUtNTIFY pr^o*- E.SS10NAL SCHOOL INVOLVED (Mvdic.tl,
uVn«.,f. (.;c.)
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
   SUPTORT METHOD ('
' UtiOj COLICATEO

 $45K
F.Y.

76
                                       FOR OFFICE USE ONLY
                                   4K
                                                PROJECT OFFICER
                                                  Dr. Gardner
                                                RESPONSIBLE ORGANIZATION
                                                  HERL, CSD,  Biomedical Research Branch
                      NO. o»' TUTJHC YEARS TCMTATIVCLV
                      ASSUMED EILrOKO CURRENT F.Y.
                                   1
                                                          STARTING DATE
                                                             9/75
                                                                            "TT.STIMATKO COMPLETIc".
                                                                            I DATE
                                                                            I    9/77 _
EPA form 5760-1 17-72)     REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BC USEO.
                                           162

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          rorm Approved
                                                                         O»B No. I58.ROOS1
 ROJECT NO. (Do nor u» Mm apace)

SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        CKA
            CT   Ueve I opmen t  or Leiiuiar Model by stem to
            Eyt.ntnitl city  from Alternate Energy  Sources
GIVC NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
 Dr.  Michael D.  Waters,  Research Chemist, BRB,  CSD, HERL
 Or.  William E.  Bowers,  Rockefeller  University
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Rockefeller University
 New York, New  York
SUMMARY OF PROPOSED *ORK - (I) Obiecllve«, (2) Approach. (3) Current Plans and/or Progreaa (200 words or leal. Otnll confidential dela).
   In thr Smithflnninn Srirnci' Informiition Exchange, luminaries of work in progress ar« exchanged with government and private agencies sup-
porting research and are forwarded In Investigators who request auch information. Your summary la to be uaed for theae purposes.

       The contractor shall  conduct  a  series of  cytological and biochemical  experiments
 designed to define the nature of lymphocyte cytotoxic activity.  Specifically, the
 contractor shall  identify those  bioenergetic and biosynthetic pathways believed to
 be important  in  the process and  shall  determine the nature  and  localization of any
 substances elaborated by the lymphocytes which are found to  be  involved  in foreign
 cell  destruction.  He shall  determine the limitations of the In vitro  response
 using allogeneic  tissues,  with special concern for potential  application  of the
 test  system to  the problem of detecting neoplastlcally transformed cells.   Emphasis
 shall be on development  of a quantitative bioassay system  in all basic research
 efforts of Phase  1.

       This research effort shall  be subject to  continuation  for  two additional
 phases if work  progresses  satisfactorily.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED fA/.-rWc.i/. SIGNATURE OF PRINCIPAL INVESTIGATOR
th-nlitl. i-fr.)
DATE
	 \ 	
FOR OFFICE USE ONLY *,*//•/' / / f ' V 	 * 	 V
SUPPORT METHOD (O.WJ. i-m-l
	 A. 	 ^ 	 ,
FUNDS OBLIGATED
$50K
F.Y.
75
TASK NO.
4 L
PROJECT OFFICER ff ^/ -CfMj^Ji '(J / /^-i^-(-t_J
Dr. Michael t). Waters
RESPONSIBLE ORGANIZATION
Fnviroin^ntai Protection
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
i
STARTING DATE
11/75
Agency HERL, RTF
ESTIMATED COMPLETION
DATE
8/9/79
EPA Form 5740-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                        163

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form Approvrd
                                                                        OAIB No. US-ROOS1
                                                               PROJECT NO. (Do not u*e «»1« epacej

                                                               SSIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                   CKA
 TITLE OF PROJECT  Determination of  the Effects of Material  hrom Alternate  Energy
 .Sources  on llnnpr  Rpgp-lratnry Tr-art Clearance  Mechanisms.	
 IVE NAMES. DEPARTMENTS* AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJE
                                                                  JECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Dr.  Donald E. Gardner, Chief, BRB,  CSD, HERL
 Dr.  Dorothy Adalis,  Associate Professor of  Biology, Ball  State University
                   PLICANT INSTITUTION
 Ball  State University
 Department of Biology
 Muncie.  Indiana 47306
 fiuncie.  Indiana t/jut)	
 SUMMARY OF PROPOSED WORK - (I) Ohjectivec, (2) Approach, (3) Current Plan* and/or Prerreaa (200 word* or !•»•. omit confidential data).
   Tn the Smithsonian Science [iifurmullon Exchange, aummarlea of work In profreaa ire exchanged with government and private afenelea lup-
 •ortine. rmeureh nnd ure Forwarded In investigator! who request Buch information. Your •uaunarv la to b* uaed for thaae purpoaea.

       The objective  of this contract 1s to screen  a  variety of substances for their
 toxic effect on mucodliary activity: using an  1n  vitro model  system.

       Since cilia  play a  significant role 1n pulmonary clearance, proper functioning
 is essential for  defense against  various environmental insults.   However, ozone,
 nitrogen dioxide, nickel and cadmium have an adverse  effect on  this system.
 Therefore, it becomes increasingly  important to determine  if  alternate  energy
 sources  such as shale oil  and coal  gass1f1cat1on  and  liquefaction, or partlculate
 effluents  from power stations, stationary engines or  mobile sources produce  pollutants
 toxic to the mucociHary escalator.

       Due to the above considerations isolated hamster trachea!  rings will be exposed
 to pollutants jjx  vitro.   Parameters to be measured  are:

       (1)  effect on  ciliary beat frequency,
       (2)  effect on  the energy source (ATR) of beating,
       (3)  effect on  ciliary and trachea!  morphology, and
       (4)  recovery of the trachea! rings  after exposure.

       In  all  cases,  parameters will  be  tested for  dose-response  effects.
OENTIFY PROFESSIONAL SCHOOL INVOLVED (MvMc.it,   SIGNATURE OF PRINCIPAL INVESTIGATOR     DATE
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD (Cti.-,-k ,»i,-l
FUNDS OBLIGATED
  $30K
  $40K
75
76
                                  4M
                                               PROJECT OFFICER
                                   nr  Ponald E.  Gardr
                                  ESPONSIBLE ORGANIZATION
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
               2
                                   Fnyirnnrr|prH-al  Protection .AqeP^V" HERL. RTF
                                                                IMATEO COMP
STARTING DATE

  10-75
                                                                            ESTIMATED COMPLETION
                                                                            DATE
                                                                     5/79
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-S1E 76* WHICH MAY NOT BE USFD
                                       164

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED TOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
      PROJECT NO. i

      5SIE
                                                              CKA
TITLE OF rHaje.(.i Assessment of,the JPQs.tnatal,Develpprne,nt and Function of the Central Nervous
 System of Monkeys Exposed to TritiatedT water Tr6m Conception to Birth or Weaning
ZlVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED HI THE PROJECT.!,. S. Otis, Director Psychoblology & Physiology
 "(Project Supervisor); D.C.L.Joaes, Program Manager Environmental Physiology  (Principal
 Investigator);  C.Mitoma, Director Biomedical Research; R.A. Barth, Director Food & Bio-
 sciences Dept.; S.J. Jackson, Director,  Animal Care Services; D. P. Sasmore, Manager
 Pathology Program; J.S. Krebs, Senior Biophysicist; J.N.Kaplan,  Program Manager (over)
NAME AND ADDRESS OF APPLICANT INSTITUTION
  Stanford Research Institute, 333 Ravenswood Avenue,  rMenlo Park, Calif  94025
SUMMARY OF PROPOSED V.ORK - (1)
                                i. (2) Approach, (3) Currtfm PUni and/or PrO£:eja 4200 worjl Of less. OtJlil confidcr.u
      viriirch mid arc Forwarded to investigator* who request such information. Your summary is to be used for these purpose*.
      The purpose of this study is to obtain dose-response relationships for the effects
  of chronic exposure to tritiated water (HTO) on the development and function of the
  central nervous system in nonhuman primates.  Pregnant female squirrel monkeys  (Saimuri
  ciureus) will receive HTO in' the drinking water in concentrations sufficient to produce
  body burdens' ranging from O.S to 4.0 nCi HTO/ml of body water.  Administration of
  HTO will continue throughout pregnancy .and to either birth or weaning.  Postnatal growth
  and development of offspring will be evaluated using a variety of biochemical and behavior
  al indicators of neural function.  Neurochemical  analysis of brain tumors and gross and
  microscopic  evaluation of all tissues will be done at one year of age.
 lat'MTIFY PFvOr ESSIONAL SCHOOL INVOLVED i'.V«ri/(c.>'.
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                          David C. Jones
                                                                           DATE

                                                                             3/16/76
                                      FOR OFFICE USE DULY
   SUPPORT METWOC i
 ' UNCO CG1.IGATFO
               76
                            TASK NO.
                                  sc
                                               PROJCCT OFFICER
                                               RESPONSIBLE ORGANIZATION
                                               HERL, RTF
                                    R? 7C'(T*TivCLY
                        .
                      ASSUHLO EJLiONO CUHHENT F.Y,
STARTING DATE
   12/1/75
(.STIMAT^OMP^
 EPA Fo,m 5760-1 (7-72)    REPLACES PH5 FORM IC6 ANO SI-SIE 7GA WHICH MAY NOT SE USEO.
                                         165

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                         O.IIH .Vo.
                                                                              i /l/>/»riji fit
                                                                PROJECT NO. fDo net u«* lfi»« *p*ce)

                                                                SS1E
                                                                       CQC
TITLE OF PROJECT
arcinogenic Photooxidatlon Product from  Petroleum  PAH's at Air-Sea Interface
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Or.  J.L. Laseter,  Professor and Chairman,  Department of Biological Sciences  AND
 Dr.  6.W. Griffin,  Professor,  Department of Chemistry
 University of New  Orleans
 New  Orleans, Louisiana  70122  (504) 288-3161
NAME 'AND ADDRESS OF APPLICANT INSTITUTION
 University of  New Orleans
 New  Orleans, Louisiana  70122
SUMMARY OF PROPOSED *ORK - (1) Objectives. (2) Approach. (3) Current Plan, and/or Progress (JOO word, or lass.  Omil confident!*! data).
   In the Smithsonian .Science Information Exchange, luminaries of work in progress are exchanged with government and private agencies sup-
porting research und are forwarded to investigators who request such information. Your summary is 'o be used for these purposes.
       The primary purpose of the proposed program will be to  determine  the major

  photooxidation  products of petroleum  derived polynuclear aromatic hydrocarbons  (PAH).

  These studies will  be designed to partially elucidate "weathering"  phenomenon of

  petroleum at  an  air-water  interface of marine environments.   Particular attention
                                        /
  will  be given to the photooxidation products which  may have  mutagenic  or other

  biological properties.  A  portion of  the program will involve chromatographic

  resolution and  mass spectrometric characterization  of aromatic hydrocarbon and  their

  biologically  significant oxidation products in  previously collected field samples

  collected at  the air-sea interface.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED f.UriHcol.   S«5N«Y/T
-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
 TTF<
                                                                              Form t\pptui-ed
                                                                            OMB No. U8-R0081
      PROJECT NO. (Da mil use Ihla space)

      SSIE
             CQC
             CTAlr, Water, and Multi-Route  Exposures and  their Effects: Pollutants
               Associated with Energy Development.
 WE NAMES. DEPARTMENTS. AND OFFICIAL TITLES Of PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

  Dr.  Norman  Richards, Dr.  W. Peter Schoor, Dr.  Nelson  Cooley,  Dr. Gerald  Walsh,

  Mr.  Lowell  Banner.
NAME AND ADDRESS OF APPLICANT INSTITUTION
  U.S.  Environmental Protection  Agency
  Environmental Research  Laboratory
  Sabine Island,  Gulf Breeze, Florida   32561
SUMMARY OF PROPOSED WORK - (I) Objective.. (2) Approach. (3) Current Plant and/or Progress <200 words or less. Omi< confidential dm.).
   In the Smithsonian Science InforfKation Exchange, summaries at work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.



   Constituents of and compounds  rerived from petroleum hydrocarbons may accumulate
   in portions of  the marine food chain consumed by man.  The  objective of this  research

   is to  provide an assessment  of the  potential for accumulation of  specific

   carcinogens found in  fractions of shale oil.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED f.Uoiifcol.
 dt'iifaJ. t-rt-.J
                                            SIGNATURE OF PRINCIPAL INVESTIGATOR
                                            /TfAvLOn*-  e\
                    DATE

                     Sept.  30, 1976
                                          FOR OFFICE USE ONLY
    SUPPORT METHOD (C/n'C* Una)
     AGENCY 5T AFF (Intramural)
     RESEARCH GRANT
 FUNDS OBLIGATED
                                                   PROJECT OFFICER
                                                       Dr.  Norman _Lj_Richards_
                                                   RESPONSIBLE ORGANIZATION

                                                       Gulf Breeze^Florida
                        NO. OF FUTURE YEARS TENTATIVELY
                        ASSURED BEYOND CURRENT F.Y.
STARTING DATE

   10/77
ESTIMATED COMPLE
DATE
                                                                                     10/78
 EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A *HICH MAY NOT BE USED.
                                              167

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              U.S. ENVIRONMENTAL PHO1 ECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                              PROJrCT NO. lf>n nut uxr thin

                                                              SSIE
     PREPARED COR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                   CLA
TITLE OF PROJECT Effect of Environmental Pollutants In Relation to Age & Dietary Influence
  I. Toxic Trace Elements	    • 	_	;	
GIVE NAMES. CIEPARTMCMTS. ANO OFFICIAL TITLES Or PRINCIPAL INVESTIGATOflS OB PROJECT DIRECTORS ANO ALL OTHER
PROCESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 "Dr. Krlsta Kostlal, Head, Dept,  of Mineral Metabolism,  Institute for Medical Research

  and Occupational Health, 158 M. Pijade,  41000 Zagreb,  Yugoslavia

  J.F.  Stara, Project Officer,  U.S. EPA
NAME *MO ADDRESS OF APPLICANT INSTITUTION
  Institute for Medical Research & Occupational Health
  157 M. Pijade, 41000 Zagreb,  Yugoslavia
SUMMARY OF PROPOSED V.OPK - tl> Ob-.-nlv^t. (2) Apprraeli. (3) Current Plan* iifirt/or PrOi?e*» ^00 worja or le»s. Omil confider.ii.-.: data).
purlinc research *id are farwarded 10 investigator* wha rrqueif «uch infofmallon. Your lummary i» to be used (oc thc*r purpo»B».

     This work is  intended to evaluate various factors influencing the effect of environ-
  mental pollutants with particular emphasis on trace elements.
     Special attention will be. paid to differences in absorption,  distribution and retention
  in relation to age,  to the  estimation of critical  organ in the immature, to differences in
  toxicity due  to age, to late effects  caused by infant exposure and to nutritional factors
  and deficiencies as influencing trace element metabolism and effects.
     Most of the experimental work is going to be performed on rats using radioactive
  isotopes of trace elements for studying various metabolic parameters (i.e.^Cd, ^^Hg,
  203Pb, 59Mn etc.).  Stable trace elements are  going to be used as additives to different
  diets to evaluate the effect of chronic exposure and  interaction of essential and toxic
  trace elements.  The experiments on humans are envisagejfor a later stage.
     These investigations are expected to provide a better basis for evaluating the effects
  of environmental pollutants in the young.
I'JLr.IIFY PfiOf-E.SSIONAL SCHOOL »N VOl_\* £C f H
(/••n(,.l. rfc.j
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR     ' DATE
   SUPPORT MCTHCO .
  "
     TU AHC'» GRANT

 U'.DI OBLIGATED "
                                      FOR OFFICE USE O.'.'LY
                                               PROJECT OFFICER
                                               J.F. Stara
                                               RESPONSIBLE ORGANIZATION
                                                EPA-ORD-HERL
 $85,000
F.Y.   S'O. Or ryTijPC VEA^S TCNTATti
      ASSUHLO OEtOr^D CURRENT F.Y.
76&7^
                                                        STARTING DATE
                                                                            KSTlMATtO COMPLETION
                                                                            DATE
                                                                               1977
EPA r»tmS7t0.1 (7-72)    REPLACES PHS FOUM 160 ANO SI-SIE 76A WHICH MAY NOT 8E USED.
                                           168

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            U.S. ENVIRONMENTAL PWOTLCTIOM A-£f;CY
             NOTICE OF RESEARCH PROJECT
                                                    PROJECT NO. ftlo not,

                                                     5IF.
    PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                       CIA
                                        TCTD 'jJGXI
                           ^QM_MQBIL.E_^NJ)_STAT.IQ:iARY. EIIE.RGY_SOURC;iS	
.!•.! UAMCa, OEPAKIMEflTS, AND OFFICIAL TITLES Of PRINCIPAL INVESTIGATORS OF: PROJECT DIRECTORS A.'IO ALL OTMCa
 NOFCSS.O.UL P^SONNn. CMOA6EO IN THE P ,0»CT.   y>N> Pinelli/  ph . D . , ASSOC.  Professor,
Principal  Investigator; L.W. Michael, Ph.D., Assoc.  Prof., Co-Investiga-
tor, H.G.  Petering,  Ph.D.,  Professor, V.J. Elia,  Ass't. Prof.,  T.E.  Cody,
Ph.D. Ass't.  Prof.,  and R.  Christian, Ph.D., Assoc.  Prof. - Department
of Environmental Health.
NAME ANO AODP.ESS OF APPLICANT INSTITUTION

     University of  Cincinnati,  Cincinnati, Ohio  45267
SUMMARY OF PROPOSED WORK _ (1) Objectives. (5) Approach. (3) Current Plans and/or Progress (300 words or less. OrUt i-9nru.on-.ij! .lila).
  In thr Smithsonian Science Information Fxchunee, suminariei of work in proves* £re exchanged M-itli ^ovcrnn-.L-nt Ar.d private n^enciej sup-
 -rrfni! research and arc forwarded Lo invpstlfjters who request such inforrnation. Your sumtr.**/ is to be used for these purpi>»a».
     This research is based on  the hypothesis that some of  the  adverse
health effects linked by epidemiclogical studies to air pollution, of
which  the exhaust emissions from automobile  end stationary  pov.-ar sources
are major parts, may be due to  the ir.pairrr.ant of essential  traca matcil
irstabolisr.i by ubiquitous metal-binding chemicals, toxic rretals  and thsir
chelatcs.  The objectives of  this research  are a) to characterize the
mtitals  and natal-binding components of mobile and stationsiry  exhaust
emissions b) to  assess their  toxicological  effects 011 matal-dspandant
biological functions and c) to  compare and  contrast selected  biological
parameters in aninals subjected to total exhaust emissions  and  to
individual components of those  emissions, in particular sulfu.ric acid,
sulfates and carbon  monoxide.   We have established that catalyzed auto
emissions are less toxic than non-catalysed emissions, both in  whole
exposed  animals  and  in cell cultures; certain biological effects v;ers cua
to CO  concentration  in the exposure chaKbers, but others, such  as
impaired growth  and  organ damage,  had to ba  attributed to components of
emissions yet to b=  identified.   We have established the presence in
automobile and stack emissions  of mstal-binding agents and  their inhibi-
tory effect on matalloenzymes.   We have observed protective role of
nutritional zinc, a  micronutricnt, on the toxicological effects of load.
Inhalation studies showed that  1I2S04 was less toxic than A12(SO^)3/ thus
indicating that  the  toxicity  residssin the  matal ion rather than in SO^.
Comparative studies  on the  chemical characteristics and toxicity of
stack  emissions  from pov/er plants fired with coal from eastern  and
western  regions  are  in progress.
TI-'>;TII v PPaf LS3tO-iAL SCHOOL INVOLVED ;.WuJi»;..f.
• t'-ttl.tl. .-:t.l
  'College of  Kadicine

                                FOR orFics fit OM.r
                                                                       »
                                                                      7 7^._
.',' 1 ':• ^ •: : i A I i ' ccr.ir.&^r


1 "•-  v.'i IUATTO T «.Y.  jf:.-l. O1-
                                        	..
                                        Hi'. :.r'orr.it111  ,•.(••:,AM : f ?;.•:.
                                           .' HERL, EPA - Cinn,  .
                                                                EMI'IATt;i
                                                                DAI C
                                      169

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEAP.CH PROJECT
                                                                      OVtt XL. I'<-K',:,XI
                                                             PROJECT NO. lOo rial via M>ii >,,/,...;
                                                             SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE 1NFOKMATIGM EXCHANGE
                                                                CLA
                                                fcnergy  consuinpcion  and "Lnviron;.ioni
 TITLE OF CROJECT  EHect  ot Pollutants
5IVE NAMES. DE»»HTVEHTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AHO ALL OT>,£«
PROFESSIONAL PF.RSONNEL ENCAGED IN THE PROJECT.
  M.  G. Mustafa, Ph.D., Adjunct Assistant  Professor
  D.  F.  Tierney, M.D,  Professor
  A.D. Hacker, Dr.PH,  Postgrad. Res.  Biochemist
                                  Res.  Biochemist
                                   •jciate	
  J.J. Osoital, Dr. PH,  Postgrad. Re
  N. frlsayp-H, M.S. , .Sfaff? Hog,  Assoc
NAME ANO ADORERS OF APPLICANT INSTITUTION
  Regents of the University of California, School of Medicine - UCLA
  Los Angeles, California,  90024
SUMMARY OP PROPOSED WORK - (1) Objective*. (2) Approach. (3) Current Plans and/or Progress (Jed woniu or IBIS. O»!l carfiitrnluil tfa:.ti.
   In the Smithsonian Si-w-n*-** liifurmuiion E*chant;*. summaries of work in pro press are extftunc*d with covfrrntnent i>nd private j(-«netes tup*
[•oflirifi rcxrurch u*iJ «are forwarded to investigators who irquest >uch information.  Vour sunimary Js 10 be used for these pur^iaies.
   Tne objective is  to determine qualitative and qusiititative biochemical  charges in tha
 Ivngs of animals eroosed to pollutants related to energy consitr^tion, viz., ozona,
 nitrogen o:-ddes, sulfur oxides, sulfuric acid,  sulfates and envirornsntal trace rascals.
 Aniiftals  (rats)  are  exposed to pollutants and the  effects in the lung  are  delineated
 using 'sensitive biochemical pararnaters.
   The findings  of studies  to date are suncarized  as follot<7S.   Although  acute exposures
 to oxicUnt pollutants generally cause a depression of lung enzymatic  activities,
 exposures to  ozone  at concentrations below  1 ppm  (sinrolating sroient  conditions in
 photochemical snog) and to nitrogen dioxida at 5  ppm (Threshold Limit Value)  for a few
 days or longer  result in a stimulation of lung instabolikn.   As judged fra?. en^-catic
 activities, lung trctabolism may exhibit an  initial depression (within 24  hours) but
 a subsequent  elevation viiich attains the peak  between 3 and 4 days of exposure.  For
 e^sosures   involNdng 0.8  ppm ozone, a 50-100% elevation of metabolic psrsnaters has
 been observed.  For la-rar  levels of oscna (viz.,  0,5 and 0,2 ppm)  the  iratcbolic
 changes are small,  ej-Mbiting prolonged exposures to ozone (viz., 0.8 ppm)  shew that
 the biocheriical changes in the lung remain  elevated for as long as 50 days of exposure,
 but than decline almost to control level after 90 clays of exposure.   For  lover
 levels of ozone, tha  changes are found to revert  to control level within  20 cUiys of
 exposure.  If the exposure is discontinued  after  a few days,  the biochemical chsr.ges
 in recovering amnsls return to c -itrol level  within a week.   It nay  bs ccncludnd
 that lc-.-;-levcl  oxidant expostires '.ause biochemical changes in the lung, and that the
 changes are reversible.
                                                                          OATF

                                                                          Angus L- 9, 1976
$237,355
                                           170

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              U.S. ENVIRONMENTAL PRGTCCTION
               NOTICE OF RESEARCH PROJECT
                                                                        Form Appro; cj
                                                               ROJtCT NO. fOo r«,l u.ie this I

                                                              SSIE
     PREPARED FOR THE SHlTHSONIAM SCIENCE INFORMATION EXCIIANOE
                                                                  CIA
                         'tftects of  Catalytic emission  Components and Effects  of  ErieTgy
                         ?ci Tract* I!gtals_on_guln'.onBr.v. f-'acrpnolecular Metabolism	
                         V t tf~.lt. I TITI k"t rtC C>f>lM(~IOAI  liu^rrcTf^ATr, Be >-\a on,-*. . e-j- 1- mntr^-i-Hm- , .. ^ . . . __..,._
	 _	3CA« ' WL*"V|.'A..u.'i I—LrVMjUkt VVtU	1 i m-cz i ,^ UU-U	UU	T-U-LLllUj lCi.J_V—LJ^V. I Vi.'>j_i C^j.1 I C. I  I.U :,P i-»tj_!_| >tj|
Give NAMES. DEPARTMENTS, ANO OKMClAL. TITLES OP PRINCIPAL IN VCST1OATORS OR PROJECT DIRECTORY AMD ALL OTHER
PROFESSIONAL PEftSOHNEl. ENCAGED IN THE PROJECT.
              Rajendra S.  Bhatnagar,  Ph.D.
              Professor of Biochemistry in Residence
              School  of Dentistry—630 Sciences
              University of California, San Francisco
              San Francisco. California_94143	
NAME ANO AOOKFSS OF APPLICANT INSTITUTION
              School  of Dentistry—630 Scineces
              University of California, San Francisco
              San  Francisco. California. 94143	
SUMMARY OF POOPOStO WORK - (l> Ob j«-(. lives. (2) Approach, (,)) Current Plan* a.vf.'er Progress (200 word* or less. Omit confidential e!aTc>.
  t/i I hi* Smiih*or(init rcsejitch aid ,,te fi-rwaHi-d i^ investtt-ptors who re-quest such ir.fornu.iiR;.. Yotir ^u.iirriry is (o be used far thttt p'.irpo»tfs.
 There  is mounting  concern over the  increase in ateospheric  concentrations of a variety
 of metallic pollutants associated with energy consumption  f.nci  changing energy sources.
 With a few exceptions, very little  is known about the  toxicity and long range health
 effects of rr.any of these metals.  We have previously developed a highly reproducible  &
 controlUble lung  organ culture  syste;:] for the evaluation  of several snviron:r.s!ital
 toxins;  our studies  provided useful  information concerning the toxicity of these  sub-
 stances and also yielded information concerning the molecular  mechanisms involved   in
 these  toxic interactions leading to pulrr.or.ary disorders.   In our origin?! contract
 with the EPA, v° examined the toxicity of the   metals Pt,  Pd  and Cd and initiated
 investigations on  the effects of Ho on pulmonary tissues  in organ culture.  Because of
 the  suitability and versatility  of  this procedure, we  propose  to use our lung organ
 culture system for investigating the biochemical effects of the energy consu^ption-
 related trace metals,  Ru, Hi, Hg, Cu and Zu.   In this  proposal  we propose to (1)  Deter-
 mine effects of these trace raatals  en pulincnary connective  tissua biosynthesis using
 lung organ cultures;  (2) Determine  the dose response of these  compounds; (3) Dstcmvins
 qualitative and quantitative changes in collagen induced fay above pollutants. Similar
 stu   2S will be initiated with elastin;  (4) Correlate  observed-biochemical changes  with
 morphological  lesions; (5) Parameters of collagen synthesis will ba e/.aTiinsd in  lungs
 of rats exposed to the above pollutants, at tho EPA, Cincinnati,  l-.'e will also inves-
 tigate the effect  of Cad.Tnutf on  the synthesis of connective tissue macroiroleculcs.
 Further additions!  studies in relation to the metallic pollutants will involve
 examination cf the interactions  of  the toxins with critical  enzymes involved in  con-
 nective tissue mDcrcrr.olecular synthesis to determine their  sitns of action.  Studies
 will also be carried  out to determine the effect of the shove  pollutants on informa-
 tional r.iacromolociile  synthesis in lung organ cultures.   The effects of these trace
 petals on Kin and  Ki-iA synthesis  will  be investigated.
       >'«.or I silONAL SCHOOL tr-i\ OLVLU i.W. i
.1.1,:..:. .;..]

  School of Pantistry
                                         SluNATl'HC. Of PRINCIPAL IMVE.STIOATOH
                                         ''? ^  'ty'/v/T^'V?'! ••'  '-^  •   R/-/76	
                                      FOB
                                             171

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                        PROJECT NO.
                                        SSIE
                                                                    CLA
TITLE OF PROJECT ^iv< h;ater an Objective*. (2) Approach, (3) Current Plan* and/or Progress (2CO word* or Icfti. O:;.it confidential data>.
   [n tht> Smilhsoninn Srirnf c Inrurni^tion Exchange, vucnmarictt of u-cr^ in proe"** 4r« tfteh^nsed with Government And privjrc agenel*! cul^
porling rcsvurch :irtd arc furw^rdrd lo invcvtic^kOfi who request xuvh inforrution. Yaur xummary i> to l>e vuctj for thoe purpoaev.
       Studies have been  designed to  assess the health effects of  exposures  to  sub-
 stances which pollute air and water as a result  of  energy technologies.  Enphasis is
 being placed on potentially toxic agents resulting  from fuel extraction, conversion
 and  combustion.  The  evaluation of  the toxicty of the pollutants and their metabolic
 products include a  spectrum of bioeffect indices.   The present program includes:
       (1) The assessment of exposure to toxic organic chemicals which are associated
 with energy processes and which reach  man through water.  The investigations  include
 screening for potential carcinogens, mutagens, and  teratogens in water supplies, as
 they result from energy sources emphasizing coal and shale oil processing.
       (2) Toxicologic  data are obtained for multi-route exposures from metal pollutants
 resulting from fossil fuel extraction, combustion and conservation.   The establishment
 of additional physiological and biochemical indicators to establish  a more sensitive
 dose: effect data base  include studies of age sensitivity and influence of dietary
 composition on absorption, deposition  and toxicity  of the trace  elements which pol]u'ce
 the  environment from  energy-related sources; lor^-term effects of inhalation  exposures
 to toxic components of  fly ash; biochemical effects of energy related trace metals on
 pulmonary macromolecular metabolism.
iti-i-i.>r. 11.-. i

  lir.lll.-Cincinnati
                  . 5OIOOL INVOLVE i' •\.'.-t;j.-.,/t
                                         SIOMATU^E OF PH1NCITAL IMVCSTIC-ATOfi
                                                       7/1/76
  T«"
 " '".".

               FOB Of HCE JJJ r: 0>4L Y	

                        ' J1.'"F^.St'a-a
                          "I T:^'n   001
                                              I •'LS--'
--. J 	I. .liH.X, OKI"!,. Li'aU.,  OI'O ..
                                 ' ST AHTt.'IC. D-;". L

                                   10/1/76
                                                                                10/1/77
                                           172

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE C
                                                                          Furrli Approvtd
                                                                        win /vo. ;38-ROOST
               PROJECT NO. (Da not uae Iflla spacs; c..ul>iu  u.  ui !.i_ . J.
   active metabolites.  The data  generated  from such a comprehensive screen
   allows the direct correlation  of all the various tests  in the same animal
   under the same  conditions.   This proposal  will attempt  to develop the.
   optimum conditions for integrating seven discreet measurements for muta-
   genicity into a siiigle test and illustrate the activity  of  standard mutagens
   and environmental agents in this approach.

         Since the  majority of  known carcinogens are also mutagenic the use of
   these procedures  should detect carcinogenic as well as  mutagenic agents in
   a  fraction of the time needed  for conventional carcinogenicity tests.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED r.Vedfcol.
denfn/. flc,)
   University of Texas Medical  Branch
            (Modicnl  School)
                               3/5/76
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD (Check one)
                                  IF
                                                PROJECT OFF
RESPONSIBLE ORGANIZATION
  EPft    	
FUNDS OBLIGATED
                      NO OP KUTURE YEARS TENTATIVELY
                      ASSURED BEVOHQ CURRENT F.Y.
EPA Foro 5760-I (7-72)     REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT 3E USED.
                                           173

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•J.i. EMVIft-.INVitrAU PHOrSCflON AliNCY
NOTICE OF RESEARCH PROJECT
P3SPA3EO FOB THS SMITHMMUH SCIENCE JMrOSMATIO.N EXCHANGE
i>SSfrlf££.ii
PrJOJECT MO. rD»iwf u»« •>.. .p«t--J
351 £
ir-A
CLA
  --£t--?=OJSCT  coinparativa ToxicoiogicaJ. Assessment or  ily «.sti irom  v,«scarn a.-i
                Fpctp-^ri Coal
   S NAV£3. OEPARTMSUTS. iHO OFFICIAL TITLES Of PSINCiPAL INVeSTICATC^S OS PROJECT DIRECTORS AMD ALL OTH5B
   :FZ»alONAL PERSONNEL. ENGAGED IN THE PROJECT.
      Dr. William E. PepelJco,  Project Officer
     A.NO A333ES5.OF APPLICANT INSTITUTION
                             Interim Report
 5j««A»Y CP PSOPOJ^O wOa:< - (I) Objectives. (2) Approneh, (J) Current Flam and/or P.ejrss» (203 words or !••*. Omit eanltd«-riT,»l djt»;
   >. :h* SraithicnUrt Sett nee Information E^rh*»xtfK. *umfn>rtr>s ct wrfif in proc'*** »'• «xcS«int*d with gtvcranem and privac* ngtnclui sup*
 ?*f:ir.< r**earch nrd arc forwarded to lav»a:igwtor* who r*qu»»t such Infariuticm. Your »crim»ry IK tD b* used for th**» purpos**.
 The  objective of tha proposed investigation is to provide sufficient data "en  the
 potential  toxic effects arising fron e:raosura to airborne effluents froa coal
I combustion.  Since coal froa the Western parts of  the  country will  undoubtedly be
, used in increasing amounts in the future,  it would be  prudent  to  evaluate the
j potential  hazards of emissions fron Western vs Eastern coal.   Only  limited data
I is presently available  concerning the tOKicslogical  effects of coal fly ash and
 none is available fron Western coal sources.

 Fly  ash sanples will be collected directly frcn the  effluent o£ a power generating
 plant,  dawnstrean  froa an electrostatic precisitator.   Two  sources, one burning
 Vfestern coal and one burning Eastftrr. coal, will bs utilized.   The ash sanpias will
' be analyzed for trace  elersents as well as najor conponenta.

 Two  ty?as of studies will be condacted.  T1:a first will be  acute  (1-7 days' duration)
 to establish lethal  concentrations.  The second will be chronic  (6-11) norvcliS.
 Concentrations  of  fly  ash aerosols  will range  frcn just balow  lethal levels down
 to  that found  under  aabient conditions in the  inrediata vicinity  of the generating
 plant.

 At least 3  species of  aninals will  be tasted.  Measurements will  include survival,
 growth, pathology, blood analysis  including  acid-base neasurecunts, heczatology,  and
 pertinent blood chaaistry and  enzycii determinations, tissue analysis fcr trace
 •ratals and  a variety of pulaonary  function tests.

 Present plans  are  to award tha contract during late 1975  and begin work by January
  I37&.
                  . SCHOOL irtVJLVrlO f
                                      11.  ISICIiAl'JHfc Of r'RINCIPAL INVES7IGATOH
{ .  .__• ; :'_^2^J ''~ ~"°?  Cl..-.:i i.—I    pr»»r! MO.



'    	"	    f
                                       FOR OFFICE USE ONJ.Y
           \:n i J.MTI ACT
                            'r
                                                  	Ur. yilllaa ?i_J?ep^
                                                F!t:r.^or7 'Mu.K Gtt£4»i..r ATKIN
 '  '•: ; r, >_i-,jiYifo I ^.v7

   230.0  <£a) !
                                                                            TT-.TiMii i_r> ,
                                                                            I CIA I f.

                                                                            \"~
                                               174

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                   PROJECT NO. i
                                                                   SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE

TITLE Or PriOJ
                                                                        CIA
          >jtcT investigation  of Eitects or.  1'rolonged lnhaIatTori"oT"J
          £l^&sh in Syriaii^o JUi^di J&mslfi£s.
                                                                                  i ^Ent'
GIVE NAMsS. OEPOPTMEMTS, ANC OFFICIAL TITLES OF PRINCIPAL IN VESTIOATOR5 OR PROJECT DIRECTORS ANB A' L OTx
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT,                                             -twin
       Dr.  Alfred P. Kehner
NAME AMD ADORERS OF APPLICANT INSTITUTION
   Battelle.  Pacific Northwest Laboratories
   P.O. Box 999
   Richland,  Washington 99352
SUMMARY1 OF PHOPOSEO WORK -  (I) Objective*. (JJ Approach, (3) Cu.-.-em PUlU and/or Progress (130 words or less. O.1>:1 conficVntiiil Jat.,).
   In rh*> Smill>coni,m Science [iirurcnution Kxchancc, sumn.ories ot work in progress am exchanged with eovernr.wnt and private agrnrlrs sup-
porting research and are forwarded to invealicators who request such information. Vour summary la to be used for these pu.-poses.

        The purpose  of this  contract is to investigate the toxicology of  inhaled
  fly  ash from coal  combustion using a. novel technique.   Rather than vary  the
  fly  ash concentration alone, nickel will be added curing coal conbustion to
  produce a nickel-enriched fly.   Separate groups of hasisters will be  exposed
  to normal fly ash identically pi'cpared  from the sarao coal  and to nickel-enriched
  fly  ash.

        The contract was awarded in Sept.  1976.
lUtMlll > I'tl^it liSIOHAL SCHOOL IN VOLVEO (,«.•, Ji.-.J.
                                            SICMATUME OF PRINCIPAL INVESTIGATOR
     • f.rt 1 1 A T 1 I' Ct'N t '« *^ 1
                                 	££;L£1£.'?UiS!; .0:--Y	—
                                                   P.PA-ORn-!l!-tlI._
                                                      .....
  3J5.0
                 77
  ._  _________________ .....
LV  ..... ST»>!1IIIO [>*n        |(sllM«-'H.cOMr-wL-'iv
                              I I1'* 1 1
           9/76             J 3/7!'
                                             175

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               NOTICE CF RESEARCH PROJECT
n;ci'A«ro row THE SMITHJOHIAII SCIENCE inron«ATio» EXCHANGE

"' ""'J>V 'combined  Testing  Protp^oj^ojMDctoctinp^
                                                                  CLA
                                                                                      _
                                                          n rnojtCT omccioiis AMD ALL or»L«
I'ron '.MCi'lAL CI "' IVINTL r.MOAC! Cl IM THE. Pt,V,)ECT.               _    c  -    n, Q »- r 1 •} C
   Co-Princip.il Investigator:   Ingcborg Nienhold, H.D.,  S.S.   039-4Z-51J6,
       Instructor  Oapt. -of Preventive Medicine & Community  Health,
       The University of  Texas Medical  Branch, Galveston,  Texas.        Prr,f,crn
   Principal  Investigator:  Marvin S.  Lcgator, Ph.D., S.S  348;16-3632, Professo
	of; [-ixvrj^tivc. t;ctlinn^J^iT:im1±y-l^lHl' ""™prsitv  of Texas Nechcal  B
KAMt AND AtlUfiLSi OF ATF'LlCANT IHITITUTION

   University of Texas Medical Branch
   GalvesLon, Texas  77550
                                                                            branch
       Of' PUOi'OC.CO WOWS -  (I) Objonivcs, (2J Approach. (1) Cu
                                                    nJ/or Pros»e»s (200 ^
        It should now be possible  to  combine many of the available procedures
   to detect and characterize  environmental  mutagens into a single animal
   experiment.  This proposal  will  attempt to develop a protocol  for carrying
   out the following studies in  a  single animal test:  (a) repair determination
   in germinal cells, (b) nricronuclei  test,  (c) rrc-taphasc analysis of bone
   marrow (d) repair determination somatic cells, (e) spermatocyte test,
   (f) analysis for blood for  active  metabolites, (g) analysis  of urine for
   active metabolites.  The data generated from such a comprehensive screen
   allows the direct correlation of all  the  various tests in  the  same eniinal
   under the same conditions.  This proposal will attempt to  develop the
   optimum conditions for integrating seven  discreet measurements for rnuta-
   genicity into a single test and illustrate the activity of standard ir.utagens
   and environmental agents in this approach.

        Since the majority of  known carcinogens are also mutagenic the use of
   these procedures should detect  carcinogenic as well as mutagenic agents in
   a fraction of the tine needed for  conventional carcinogenicity tests.
  Fi I ] f r -"F4OF L ^:-:ON'M- jCHOCL IN VOLVLD {'.u-ilif.il,
  tl.,1. ,-fi.)
   University of Texas Medical Branch
           {V.edi-caT-School-)	
                                  SIGHATUKCOF PRINCIPAL INVESTIGATOR
                                                                       3/5/76
                                    FORJ^FTICE US^ ONLY
                           TASK NO.

                                2
                                             PROJECT OFFICEH
                                                         _.
                                             r i c S f ' o N s ! < i L t; o r( G A j ; t z A T i o f (
              F.v.   I no. OF
                    1
                                                      ST AH VING DA 1

                                                         S/ 3.6/7 6
                  ntf'L A CCS *'HS f O^M If-' AND -.t-f-ts: 7JA ftt-ICii 11/xy NOT u L USt o.
                                        176

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               U.S. ENVIFIONMCNTAL
                                 ITECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFOriHATiOM EXCHANGE
                                                                ROJECT NO. fOo r

                                                               55IE
                                                                    CLA
                                                                                       d Frc;if1
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.         David J.  BrUSlCk, Pf! . D .
E.  Ross  Hart, Ph.D.,  Principal  Investigator  Department of Genetics
Department of Pharmacology  &  Toxicology       Da]e w>  Hathesoilj Ph.D.
Robert P. Bellies, Ph.D.                       Department of Genetics
Department of Pharmacology  &  Toxicology
NAME AMD ADDHESS OF APPLICANT INSTITUTION
Litton Bionetics,  Inc.
5516  Nicholson  Lane.
Kensington, Maryland   20795
                                                                            t^edicir.e & Science
                                                 Herman R. Seibold, V.M.D.
                                                 Department of Pathology
                                                 Jerry  F.  Stara, Project Officer, EPA
SUMMARY Or PROPOSED 'WORK - (I) Objectives. (2) Approach, (21 Ctrrc^t Plans anil/or PrOjjrDSS (iOO •-. ords or le.s. O-i: ccn/idtnci,! 
          f.TTnOD 'Chi ct- or. .    | TASK '
                                      _FOR OFflCE USE 0«LY_   	
                                                PMOJEC r OFFICER
— j r..1 r* ^VJi^^il^L	|  002

: '."'"'* 0 C-L I'.*,.•. I j 2 1 f-T!"
                                                        .    s
                                                 EPA, OilD,  HliRL,  OPO
                                                            HTJUG UAT.-.
 -l'A ^'^Jr^1 57(0-1 (,'-7?)    RFf'L/ '.t r - F'HS I Ofvv. 11;, - K L'- Sl-1^ i F. ?i A AM.».tt M '• V NO I Or
                                           177

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        f~ornj Approved
                                                                      O.VIB No. I58-ROQ81
                                                             PROJECT NO. (Do not uso this 0P4C0J

                                                             5SIE
CQC
TITLE OF PROJECT	                     ~~
Accumulation and Elimination of a Certain Aromatic Petroleum  Hydrocarbon
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

Robert Farragut - Environmental Investigation Chief
Harold Thompson - Research Chemist
Jane Corliss  -  Biologist
NAME AND ADDRESS OF APPLICANT INSTITUTION
NMFS
75 Virginia Beach Drive
Miami, Florida  33149
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach. (3) Current Plans and/or Progress (200 words i
                                                                        less. Omit confidential data).
   This  study is designed to determine the accumulation and  elimination of a certain
carcinogenic aromatic petroleum hydrocarbon by selected marine test organisms of species
that  are used for human consumption.
   The two organisms chosen for the  study are shrimp and snapper.   There will be three
test  tanks maintained for each species.  One tank for each species will be used  as a
control, the second tank for each species will contain the hydrocarbon at the 1  ppb level ,
and the  third tank for each species  will contain the 5 ppb level.   Study organisms will
be sacrificed at intervals of 4,  7,  14, 21, and 35 days.   There will be three different
tissues  analyzed far the study hydrocarbon fr«n the shrimp.   They are 1) the cephalothori x,
2) the gut, and 3) the tail.  Four different tissues will  be analyzed for the study hydrt -
carbon from the snappers.  They are  1) the liver, 2) the gall bladder, 3} the gut, and
4) the flesh.  Specimens of both  species of study organisms  will be drawn from the control
tanks at intervals of 4, 14, and  35  days.  Analysis of the control specimens will be d«n<
on the same types of tissues stated  above.  Control tank water will analyzed for back-
ground levels of the study hydrocarbon at 4, 14, and 35 day  intervals.  After 35 days
exposure to both concentration levels of the study hydrocarbon, both the shrimp  and snap] erij
will  be  placed in tanks with uncentaminated seawater.  Specimens of each species will be
sacrificed for analysis at 4, 7,  14, 21, and 35 days.  Analyses will be performed on the
same  types of tissues as before,.   Control specimens of each  species will be sampled at
4, 14,  and 35 days and analyses performed on the same types  of tissues as given  above.
Control  tank water will again be  screened for background levels of the study hydrocarbon
at the  same sampling intervals as before.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED
 dental, etc.)
                                                                          Sept.  13, 1976
                                      FOR OFFICE USE ONLY
    SUPPORT METHOD (Chech one.)
    AGENCY STAFF (Intn
 FUNDS OBLIGATED
                                               PROJECT OFFICER
                                                Dr.  Norman L,. Richards
                                               RESPONSIBLE ORGANIZATION
                                                 Quit Breeze, Florida
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y,
                                                       STARTING DATE
          ESTIMATED COMPLETION
          DATE
 EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                              178

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               U.S. ENVIRONMENTAL PROTECTION ACEMCY
                MOTICE OF RESEARCH PROJECT
                                                                          o.vn NO.' US-RODSi
               PROJECT NO, (Do I

               5SIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                     CTQC
 ITLE OF PROJECT

Detection of. Carcinogens in Sea V.'ater;  Use_of  Hybrid Fish and Food Chains
 IVE NAMES, DEPARTMENTS. ANO OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 ROFES5IONAL PERSONNEL ENGAGED IN THE PROJECT.
 )r.  Douglas  Humm
 Dept. of Zoology
 AME ANO ADDRESS OF APPLICANT INSTITUTION
 University  of North  Carolina
 Chapel Hill, N.C.  275T4
 SUMMARY OF PROPOSED WORK - (I) Objective*. (2> Approach. (3) Current Plan* and/or Progress (200 words or leu. Omit confidential data).
   In the Smithsonian Science Tn/ormallon Exchange, summaries of work in progress are exchanged with government and private agencies sup-
   inc research and are forwarded to Investigators *h<> request such information. You- summary Is to be used for these purposes.
 (1)  Select hybridized fish which  are sensitive to  carcinogens  and develop a sensitive
      method for  the detection of  lesions.   Apply  this method  to the detection of
      carcinogenic pollutants in the environment.  Establish food chains  to examine
      the transmission and metabolism of  natural and synthetic carcinogens in their
      passage along the food chain.

 (2)  Hypersensitive pigment cell  bearing hybrid fish will  be  bred and  exposed to
      carcinogens.  Observations will be  made on the shape, histolytic  transformation,
      and migration of affected cells.   Food chain work will include radioactive PNA's,
      bacteria, and crustacean, and fish.
 IDENTITY PROFESSIONAL SCHOOL INVOLVED (Mctlical.
                                            SIGNATURE OF PRINCIPAL INVESTIGATOR --
                                         FOR OFFICE Use ONLY_
    SUPPORT MCTHQO fC'u-vA u'
     nrsi: Ar:cM CHAN T
   $41,1!
PHOJECT orncefl
 Dr.  Norman_L_._jy.cliards	
nCSPONSIPLE ORGANIZATION

 ERL, Gu1f Breeze  Florida
 FUNn* GUI IGATFO  F V     NO  OF F U f U 4*. vCMiS TENTATIVELY
 FUNDS OULIOATEO  F.V.    X?SURtO DEYOND CURRENT F.Y.
                                                                                         COMl'LtTIO
                                                179

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              U.S. ENVtROUMLNTAL. PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                           .Vo. 113-
                                                              PROJECT NO. (Do nor use this

                                                              SSIE
     PREPARED POR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                      CQC
TITLE OF PROJECT TOXIC,  suoiettiai and latent eitect 01 certain petroleum hydrocarbons
   barium sulfate on marine organisms
                                                                                    ancT
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.


   K. Ranga Rao, Associate Professor, Dept.  of Biology,  University of West Florida
NAME AND ADDRESS OF APPLICANT INSTITUTION
   University of West Florida
   Pensacola, Florida 32504
SUMMARY OF PROPOSED Y.OP.K - (1) Objectives, (2) Approach. (3) CU-TCI^C PUm* and'of Progress i200 >.
                                                                        • leas. O^iit confidential data).
                                              irmation. Your luminary i» to be used for these purposes.
       This investigation will examine the toxic,  sublethal and latent effects of
   certain polycyclic aromatic hydrocarbons and barium sulfate on larval and adult
   stages of selected  invertebrates and fish. Experiments are designed to determine
   the effects of these compounds  on (a) crustacean molt cycles, (b) regenerative limb
   growth,  (c) respiration,  (d) heart rate and (c) histology and ultrastructure of  selected"
   tissues.  Studies are aimed to determine the uptake by marine organisms of these
   pollutants from water and bioaccumulation through aquatic food chains.   By using a
   combination of autoradiographic and convential analytical techniques the sites and
   extent of accumulation of pollutants in marine organisms will be determined.
IJENTIPY PROFESSIONAL SCHOOL INVOLVED (M
"•""•••'• '•'-'University of W.  Florida
        Department of Biology
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                      2/10/76
                                      FOR OFFICE USE ONLY
   SUPPORT MCTHQD 'C,',,•<:fr «:
    S.GL-MCV STAFF • (i;rr.;n>,,r;tl)
   Cj OBLIGATED
  $94, 984
                                               PROJECT orricER
                                               Dr.  Norman L. Richards
                                               RESPONSIBLE ORGANIZATION
                                               Gulf Breeze, Florida (904)932-5311
                     NO. Or r U T U P C YEAR* TC', TATIVCLY
                     ASSURED BE.TCNO CURRENT F.Y.
STARTING DATE

 5/16/76
t-STIMATEQ COMPLETI3
DATE
                                                                           5/16/77
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                          180

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
     PREPARED TOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PROJECT
                                                                       Frtrni Apf"ot r.;
                                                                      OUfi A1 a MS-ROOM
                                                            PROJECT NO. (Co not

                                                            55IE
                                                                 CQC
              Effects of Petroleum Compounds on Estuarine Fishes
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
 ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

  Dr. Billy J. Martin
  Dr  Harold D. .Howse
 AM£ A.NO ADDRESS QF^APPLJCANT INSTITUTION.
  University  of Southern Mississippi
  Southern Station, Box 18
  Hattiesburg,  Mississippi 39401
SUMMARY OF PROPOSED SVOPK - (1) Objfcliv..-s. (2) Approach, (3) Cu
                                                  liins and'or Progress 1.200 words or leas, Omit confidential rf.it;
      The purpose of this project is to study chemically induced  tumors in teleost fishes
  Both marine and freshwater species will be exposed to  low levels of a known carcinogen
  for 300 days.  Fish developing tumors or other pathologies during this period will be
  sacrificed and tissue from the liver, kidney,  intestine,  and gills will be  studied
  histologically.  Tissues from all the fish with no grossly apparent pathologies at the
  time the experiment is terminated will be studied in the same  manner in order to detect
  any neoplasias or preneoplastic conditions.

      It  is expected that this research will:

      1)  provide evidence concerning the quantities of benzopyrene necessary to induce
      neoplasias
      2)  supply additional data concerning tumors in teleosts
      3)  establish the feasability of using teleost fish as early indicators of carcinogenic
      substances in the aquatic environment, and
      4)  demonstrate that this type system could  be used to screen compounds for carcino-
      genic  properties with less difficulty and expense than the methods currently employed
OtiNTtFY PKOf ESStONAL SCHOOL INVOLVED f.\fet/tc./J,


  University	^^^^
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                         Billy J  Martin
                                                                              2/4/76
                                      FOR OFFICE USE DULY
   SUPPORT METHOD .C.h.-cfc one)
                    •nil
                            TASK NO.
                                               PROJECT OFFICER
                                               Dr. John A  Couch
                                               RESPONSIBLE ORGANIZATION
                                               Gulf Breeze,  Florida
   CG OBLIGATED
                      NO. o^ FUTURE YEAR? TCNTATIVELY
                      ASSUHLD BEYOND CURRENT F.Y.
                                                      STARTING DATE

                                                         7/5/76
                                                                          DATE
                                                                          10/4/77
 EPA Co™ 5710-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                           181

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                       O.M/I NO. nit-Room
                                                              PROJECT NO. (Do not uaa Oil. apaeoj

                                                              SSIE
                                                                 EPA-IAG-D6-E681-BAN
TITLE OF PROJECT
Quantitative Mutagenesis Testing in Mammalian Cellular  Systems
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

Hatch, F.T., Principal  Investigator, Biomedical Sciences  Division
Carver, J.H., Lead  Scientist
Branscomb, E.W.
Galas, D.J.                                                           	
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Lawrence Liverniore  Laboratory
 P.O. Box  808
 Livennore, Ca. 94550
                                 Phone:   (415)  447-1100 x 3563
SUMMARY OF PROPOSED WORK - (I) Objacllvea, (2) Approach, (3) Currant Pl.ru and/or PrOfrtM (200 worda or laaa. Omit confidential data).
   In the Smlthionlan Sciancv Information Exchanf*, curamariaa of work In profreaa ara aachanged with fovemmant and prlvata aeanelas tap-
porting research and ara forwarded to inveallvatora who r*qu*lt «uch Information. Yowr aumroary la to bo uaad for theao purpoaoa.

      Objectives of this project are:  (1) to  develop and apply quantitative multiple-
marker assays utilizing cultured mammalian cells for the  evaluation of potential
mutagenic effects of agents derived from energy technologies,  and-f 2) -to-use  these
existing and newly-developed biological screening systems for the identification of
mutagenic agents associated with coal and oil shale extraction,  conversion, or utiliza-
tion.
      This program proposes  the use of multiple drug-resistance markers for forward
mutation in cultured Chinese hamster ovary  (CHO) cells, as well  as in vitro and  host-
mediated in vivo/in vitro procedures in the  Syrian hamster embryo (SHE) system.   The
markers being developed measure the frequency of forward mutation at the recessive
azaadenine-resistant marker, the X-linked azaguanine-resistant phenotype, and the domi-
nant  ouabain-resistant  locus.  Established procaryote and lower  eucaryote 'systems will
be used for comparison  and  reference; the most satisfactory markers in all systems will
then be combined into a standard protocol in which each of the gene loci can  be  meas-
ured for mutation following exposure to a particular test agent  or combination thereof.

      Progress to date has been:  (1) Selection and validation of three CHO cell  lines
heterozygous at the adenine phosphoribosyltransferase locus.   These stock lines  have
been tested for optimal cell plating, selecting drug concentration, and expression time;
the cell lines are now being used in triple  marker mutagenesis experiments.   (2) The
SHE system has been tested  extensively-plating efficiency optimized, ouabain  resistance
determined, with work currently in progress  to optimize the azaguanine-resistance
marker.  Both CHO and SHE systems have been  tested with the standard mutagen  EMS,
and experiments utilizing specific hydrocarbons relevant  to energy technology are now
underway.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Mcdlcat.
oVnru/, rre.J

 NA
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR      DATE
                                     FOR OFFICE USE ONLY
   SUPPORT METHOD fOicc* <
FUNDS OBLIGATED
 $100K
F.Y.

1976
                               #1
                                                             .  Stapleton
                                RESPONSIBLE ORGANIZATION

                                 AAES/ERDA	
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
       Three
STARTING DATE

  June 1975
                                                              June 1980
EPA Form 5760-1 (7-72}     REPLACES PHS FORM 166 ANO SI-SIE 76A WHICH MAY NOT BE USED.
                                         182

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                 NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          Form Affr,,,vJ
                                                                        OMH No.
                                                                ROJECT NO. fDo ,«,,„..,«. ,
                                                               ssie
                                                                 EPA-IAG-D6-E681-BAN
  Morphological Variants in Damaged Sperm
 GIVE NAMES. DEPARTMENT"    ^
                       O OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.                             """M.IU.IS AND ALL OTHER


  Wyrobek,  A.J., Principal  Investigator,  Biomedical §  Environmental Research  Division
 NAME ANO ADDRESS OF APPLICANT INSTITUTION
  Lawrence Livermore  Laboratory
  P.O.  Box 808
  Livermore, Ca. 94550
                                          Phone:   (415)  447-1100 ext.  3559
SUMMARY OF PROPOSED WORK - (I) O»j«tlv... (I) Appro..!,. (3) Cm.n. PUn. and/or P»pc.> (fOO »ord. O, I.... Omll CMfld.mbl
  In the SmlUuonlan Science Informally, E«h«n«e, • unm.rle. of »grk In projr... „. ..chanted with eovonunent and prlv.u »(cncl» >
perUni remreh «d «• forwards to lnv««llgalori who raquett >uch Information. Vow »umr-jf j U 10 be mid for lluee purpo»>.
                                                                              Omll CMfld.mbl d.t.)
                                                                                        up-


       Ionizing radiation as well as various mutagens, carcinogens and teratogens are
 known to  induce elevated levels of morphologically abnormal  sperm in mice.  The ob-
 jectives ~of -this~ study-are— 13 - to further-develop and apply  the detection- of morpho-
 logically abnormal mouse sperm as a rapid, simple quantitative assay of the patho-
 logic response -of the. male gonad to toxic agents, 2}  to extend the studies in the
 mouse to  the hamster  and 3)  to develop '-thennethodology -pf automated scoring -of ab-
 normally  shaped sperm,  especially after  the exposure of the  male to toxic agents.   Of
 special interest are  possible effects of the chemical pollutants associated with the
 recovery,  process stream and emission of nonnuclear sources  of energy especially coal
 gasification and oil -shale extraction in_ situ.

       To accomplish these objectives, groups of -test mice have  received subacute or
 chronic exposures by  injection, inhalation or dermal application as is appropriate.
 The percent of -abnormally shaped epididymal sperm will be  determined as a function
 of dosage and time after exposure.  These results will be  compared to those obtained
 by more conventional  mutagens,  carcinogens and teratogens.  Preliminary studies with
 the hamster and mouse have shown that these two species are  qualitatively very simi-
 lar in response.  Furthermore, we are attempting to distinguish sperm morphology in
 these species based on  suggested differences in fluorescent  dye uptake.  These results
 may well  lead to automated analyses of sperm morphology.
 OENT1FY PROFESSIONAL SCHOOL INVOLVED (M
dtntnl, etc.)
   SUPPORT METHOD fCdcrk uoc)
    ACENCV STAFF f
:UNOS OBLIGATED
   $60K
               1976
                                #2
                                                IQJECT OFFICER „
                                                 Dr,  George E. Stapleton
                                              RESPONSIBLE ORGANIZATION

                                              	AAES/EBBA_
NO. Of FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.

        Three
                                                        STARTING DATE

                                                        June 1975
                                                                          ESTIMATED COMPLETION
                                                                          DATE
                                                                            June  1980
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 ANO SI-SIE 76* WHICH MAY NOT BE USED.
                                          183

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                 Form Approved
                                                                OMB No. 158-R0081
                                                        PROJECT NO. (Do not use this apace)

                                                        SSIE
                                                         EPA-IAG-D6-E681-BAN
    TLE OF PROJECT
   Development of an  In Vitro Assay for Co-Carcinogensis  of Coal/Oil Shale D«
   GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.

        Byfield, John  E.,  Dept. of Radiology  (UCSD), Professor of Radiology
                  and Medicine
   NAME AND ADDRESS OF APPLICANT INSTITUTION
         Laboratory  of Nuclear Medicine, UCLA School of  Medicine,  900 Veteran
        	Avenue, Los Angeles,  Calif.  90024	
   SUMMARY OF PROPOSED WORK - (1) Objective!, <2) Approach, (3) Current Plans end/or Progress (200 wort* or less. Omit confIdentiaI data).
     In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agenclea sup-
   porting research and are forwarded to investigators who request such information. Your summary is to be used for these purpose*.

         The object  of this investigation  is to develop  an in vitro assay
         capable of  detecting the co-carcinogenic potential (with  x-rays)
         of materials  produced  during coal and oil shale processing. Initially
         it was proposed to utilize mouse  tissue cultured cells and an al-
         ready established transformation  assay. Initial experiments indicatec
         that rodent cells may  process lesions induced by alkylating agects
         different  from human cells and  that therefore their use as screening
         materials  might be misleading.  This was shown by demonstrating that
         a variety  of  DNA damaging agents  yielded  significantly different
         effects on  various cell  lines when  measured by  a variety  of tech-
         niques. It  was hypothesized that  a  central  difference between the
         lines (rodent versus human) may be  the "activation of oncogenesis"
         related to the strand  breakage  induced, rodent  lines carrying
         tranforming virus materials of  a complete or incomplete nature,
         which is  lacking in most human  target cells. This  is being evaluated
         through cell hybridization  analysis using hybrids made by sendai-
         virus fusion of cells  lacking either (a) different DNA repair
         enzymes or (b) (potential)  RNA  viruses.
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
   "School  of Medicine  (UCSD)
                                                      10/22/76
      SUPPORT METHOD CCdec* <
 Funds Estimate*
  [$50.000
76
                                    FOR OFFICE USE ONLY
                                           PROJECT OFFICER
                                           Dr.  George E.  Stapleton
                                           RESPONSIBLE ORGANIZATION
                                           ERDA
     NO. OF FUTURE YEARS TENTATIVELY
     ASSURED BEYOND CURRENT F.Y.
                                                   STARTING DATE
                                                   ESTIMATED COMPLETION
                                                    July 1976
*FundS approximate not for Citation . ise AND si-sie 76A WHICH MAY NOT BE USED.
                                         184

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               V.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form AffavtJ
                                                                        O.VB No. l)a-KOOSI
                                        PROJECT NO. (Do mi „„
                                        SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                EPA-IAG-D6-E681-BAN
 riTLE O
TITLE OF PHOJEC. EFFECTS OF AGENTS ASSOCIATED  WITH COAL ASD OIL SHALE  EXTRACTION
OR UTILIZATION ON CELL-CYCLE KINETICS AND ON' CHROHATIX/CtiROMQSOME STRUCTURE  '
CIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVEST1SATORS OR PROJECT DIRECTORS AND ALL OTHER '
-ROFCSSIONAL PERSONNEL ENCAGED IN THE PROJECT.

R. A. Tobey,  Staff Member, Cellular and Molecular Biology Group  (H-9)

H. A. Crissman, Staff Member,  Biophysics and Instrumentation Group  (H-10)
NAME AND AOOSIiS OF APPLICANT INSTITUTION
Los Alamos Scientific Laboratory, University of California, Health Division (MS881),
    Alanos, New Mexico   87545
 SUMMARY OF PROPOSED WORK- (1) obj«ctl.n, »zi>.i> (SOD „,,„), „ |«... Omlt confld.ruUl • *=iti«=«£« Scitix* taforo-Jtion Exch.nf.. ic=jrlt> of wwii In ;r»zr»» «r» «»ch»nf«d wilh tov.rnn.nt and prlval. aitncl<« «up-
 r«rtln| r***areh and ar» /orward*4 lo inv««tlgtler« who r«q>j*»t luch In/erBUtloa. Yow »u(R3unr 1» to b* au«d fop th**v purposvy.

 [t is  essential that  the ERDA/EPA provide  a means for detecting  and monitoring damage to
 human  populations as  a result of exposure  to various toxic chemical and  physical  agents.
 'o obtain  an idea of  the parameters to be  monitored in humans, it is  necessary first to
 establish  the effects of agents on cells in simpler model systems.  Earlier  experience
 with drugs which act  as  carcinogens and  teratogens has convinced us that changes  in
 >opulation cell-cycle distribution and alterations in chromatin  structure may provide
 useful early indicators  of sublethal damage to cells exposed  to  hazardous agents.  We
 >ropose to examine  alterations in these  parameters following  exposure to specific energy-
 related toxic substances in currently available tissue-culture systems which show promise
   a predictive indicator of response of human populations.  A technique has been
 developed  that allows preparation of both  cycling and noncycling cell populations in
 tissue culture, mimicking these classes  of somatic cells in humans.   By  combining auto-
 radlogra'phy, cell number enumeration, and  flow microfluorometry, it will be  possible to
 obtain highly detailed information regarding the  cellular kinetic response of both
 arrested and cycling  populations to treatment with toxic agents.  Results obtained to date
 indicate that DNA-interactive agents elicit different types of kinetic responses  in
 treated cells, indicating a degree of specificity of interaction between various  alkylat-
 ing and intercalating agents and the genome.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Me
 *«•»!. rtt.)
                                          SIGNATURE OF PHIMClPAL INVESTIGATOR
                                                              2=.
                                                                                 11-15-76
                                       FOR OFFICE USE OMLY
    SUPPORT METHOD rCh-tt »/!«•>
 Funds Estimate > •
   $50,000    I 76
                         PROJECT OFFICER
                         Dr.  George  E. Stapleton
                                                       ?i-C ORGANIZATION
                                                 ERQA.,
 .      uftc YE***S TENTATIVELY
SSURED DtrONO CURHfiMT F.V.
                                                          STARTING DATE
ESTIMATED COMPLETION
SfJfy 1976
J*Funds approximate not for citation,, ANO S,.S1C 75» »»,CM »*Y nor ae USED.
                                                185

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U.S. ENVIHONMENI AL PROTECTION AGENCY ,
NOTICE OF RESEARCH PROJECT
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
I'orm Approved
OMB No. H8-KOOSI
PROJECT NO. (Do not ue* ihlt ep«c«>
SSIE
EPA
EPA-UG-D6-E681-VAN
TITLE OF PROJECT
InVi-ao Screenina far Gene Mu*aHifjns in Mouse .Gepm_
-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
                                                                         r'om Apprvvtd
                                                                       OMB No. D&-RQOSI
                                                                   PROJECT HO. (To not urn* Ihlt ,p*ct>

                                                                   SSIE
    PREPAREO FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                 EPA-IAG-Ob-EBBl-MM
      Chemiaal Induction  of Chromosomal Abemvr-ti.fyna  in Mmjae faym r.
IVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
      W.  M, Generoso
      Biology Division
     NO ADDRESS OF APPLICANT, INSTITUTION
      Oak Ridge  National laboratory
      P. 0. Sox X
      Oak Ridge, IN  37830
lUMMARV OF PROPOSED WORK - (1) Objective*. (2) Approach. (3) Current Plan* and/or Progrea* (200 worda or !•»*. Omit confidential data).
  In Ihr Smithsoninn Science- [nfurmution Exchange, sunmarlea of work in pi-ogrec* are exchanged with government and private amende* iup-
tortine research add ure forwarded 10 Investigator* who request such Information. Your aununary 1* to be u**d for tfieae purpoaei.


  A study has  begun on three polycycllc hydrocarbon compounds for chromosomal aberra-
  tion effects in male and  female mice.

  For  each chemical the following experiments will be  performed:
        (a)  Determination in males and females of maximum tolerated  doses  for single
             treatment and for repeated treatment (daily administration  for four weeks).
        (b)  Dominant-lethal  and heritable translocation studies on treated postmeiotic
             and late meiotic male germ cells.  This will be done on  matings within
             one week after  the last day of treatment of males given  repeated doses.
        (c)  Dominant-lethal  study on early meiotic spermatocytes and differentiating
             gonia.  In  this study males treated with a single acute  dose will be
             mated during 30 to 42 days after treatment.
        (d)  Dominant-lethal  and total  reproductive capacity studies  on  dlctyate
             oocytes of  females that received single  acute dose.
        (e)   If dominant-lethal effects are induced  in  treated females,  an  X-chromosome
              loss study  will  be performed  to determine  whether the effect is maternal
             or genetic.
        (f)   Dominant-lethal  studies on postcopulation  germ cells.  Two  experiments
             will be done — one shortly  after sperm  entry and another during the
              first DMA synthesis prior  to  cleavage.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED tih;Hci,l.
tl,-nl,il. i-tc.t

    N/A                  	
   SUPPORT METHOD fC/n-cA tin,-)
                                       FOR OFFICE USE ONLY
                                      ~        [PROJECT OFFICER
                                                 Dr. George E.  Stapleton
                                                RESPONSIBLE ORGANIZATION
                      NO OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
 Funds Estimate*  F-v-
    | $53.000     I  76
*FundS approximate not for Citation.  .« *ND s,-s,E 76A WH.CH MAY NOT BE USED.
                                                         STARTING DATE
                                                                              July 1976
                                                187

-------
                  U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                           Form Approi'rd
                                                                          OMB No.  158-ROOS1
                                                                 PROJECT NO. (Do not uae ihl« «pace>

                                                                 SSIS
                                                                                   - RAM
         Mutaaeniaitu Assau  of Fractionated  Coal-Convspsion Pvodua-bs
   GtVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
         J.  L.  Eplef
         Biology Division
   NAME AND ADDRESS OF APPLICANT INSTITUTION
         Oak Ridge National Laboratory
         P.O.  Box X
         Oak Ridge, 2W   3?830	
   SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or Isms. Omit confidential data).
      In the Smithsonian Science Information Exchange, summaries of worlt in progress are exchanged with government and private agencies sup-
     Using rapid screening genetic assays  ("Ames System"),  the group is attempting to
     identify mutagenic agents associated  with coal and oil shale extraction,  conversion
     or utilization.

     Primary and subfractions of products  and aqueous discharges are being  assayed for
     the ability to inactivate and/or  revert histidine requiring mutants of Salmonella.
     Potential mutagenic fractions will be identified and  attempts will be  made to
     ascertain the specific compound(s)  responsible for the mutagenic action.  ,

     Parallel bioassays are being carried  out with selected materials in yeast, Drosophila,
     and human leucocytes.  Thus, the  validity of short-term testing for genetic damage
     will be ascertained.

     The preliminary  fractionations have been carried out  and the genetic  assays are
     in progress.  These investigations are the initial attempts to monitor environmentally
     important processes for genetic damage.  The value of short-term testing as a
     pre-screen for  carcinogenesis of  environmental effluents is being considered.
   IDENTIFY PROFESSIONAL SCHOOL IN VOL VED (Medical,
   denl.il, fie.)
                  N/A
      SUPPORT METHOD (Cheek one)
 Funds Estimate3
   I$125,000
76
                                         FOr/OffVlCE USE ONLY
                                                   Dr. George E.  Stapleton
                                                  RESPONSIBLE ORGANIZATION
                                                  ERDA
      NO. OF FUTURE YEARS TENTATIVELY
      ASSURED BEYOND CURRENT F.Y.
                                                           STARTING DATE
*Funds approximate not for citation.
ESTIMATED COMPLETION
DATE
July 1976
                                                   188

-------
                        IMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PRQJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          Form Approved
                                                                        OMB No. H8-R0081
                                         PROJ

                                           IE
                                               XPA-IAG-D6-E681- BAN
  Genetic Effects froa Electric Fields at the ChroBosooal Lrrel of Drosophila

 ^FE^OH'^f^m'M^'^a0AoeoM^e"mjKrmf"'L INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
     F. P.  Hongate,  Staff Scientist, Biology Departawat
     R. L.  Blchardsoa, Senior Besearcfa Scientist, Physics and Zas^ruttentatioa Dept.
NAME ANO ADDRESS OF APPLICANT INSTITUTION
     Battell*, Pacific Horthveat Laboratory
     Biolesy Department
     Richland. Washington  99352
SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach. (3) Current Plan, and/or Progress (200 words or I....  Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information.  Your sununarr is to be used for these purposes.
 l) Objective:  This work seeks to identify the potential for  change la the genetic
 material following exposure to IX! and AC  electric fields.
 2) Approach:  Small organisms or cell  systems are exposed  to  tmifoxB and well
 cnaractMrized electric fields and sobsequently analyzed for the  presence  of genetic
 change.
 3) Plans and Progress:  30  cm Copper discs £Lth rolled edges and central connectors
    re fabricated as the electrodes, using Incite rings 1.5  to 6 tat high aa  spacers.
    Ltial tests in which Droaophila vere sliuLtaneousIy exposed to 1500 rads gamna
 radiation and to a 300 ¥/m DC field failed to shov an inereaaedfteqn-jncy of sex linked
 lethala attributable to the  DC field.  Other exposures of Droaophila to the DC rield
 are inpprogresa  using the  Muller-5 test to eraluate frequencies"of induced aex linked
 lethala.  Cultures of g»ii«"n«»n»v vere obtained froa Dr Brace Anss and are being used
 to evaluate raxtageneai* la bacteria.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Mrtiic.il,

dVrir.-|/, i-ti:)
                                          SIGNATURE O
                                                     'RINCIPAL iNVES
                                       FOR^OTFICE USE ONLY
                                                    UXH-fl

                                                    ,ul V   '
                                                                              10/11/76
   SUPPORT METHOD (On-rfc
                                                          if
                                                RESPONSIBLE ORO*NIZATION
FUNDS OBLIGATED
   37 ooo
NO. OF FUTURE YEARS TENTATIVEL
ASSURED BEYOND CURRENT F.Y.
EPA Fertn 5760-1 (7-72)     REPLACES PHS FOR
                                  M 166 AND Sl-SIE 76A WHICH MAY NOT BE USED.
                                             189

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                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
                                                                            Form Approve'd
                                                                           Of/IB No.  158-R0081
                                                                  PROJECT NO. (Do not uao thin apace)

                                                                  SSIE
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                     EPA-IAG-DS-E-681-BAN
   TITLE OF PROJECT
   CHEMICAL  CARCP10GENESIS  OF CULTUHED RABBIT ENDOMETRIAL CELLS  - HOKMOHA.L IHTgRACTIOHS
   GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT BISECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENCASED IN THE PROJECT.
   Principal  Investigator:   L.E. Gerschenson


   Co-Investigator:          E.  Conner and J. Murai
   NAME AND ADDRESS OF APPLICANT INSTITUTION
   Laboratory of Nuclear Medicine and Radiation Biology - Univ. of  Calif, at Los Angeles
   900 Veteran Ave., L.A.,  Ca. 90024
   SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach. (3) Current Plan* and/or Progress (200 words or lea*. Omit confidential data).
     In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
   porting research and are forwarded to investigators who request such Information.  Your su
                                                               try Is to be used for these purposes.
   a)  The overall objective of this project is to study the possible  hormonal  regulation
   of the effect of chemical carcinogens  on cultured endometrial cells.   This model has
   been shown to be responsive to the "in vitro" addition of estrogens and pzogestins.

   Since estrogens have been found to have a "promoting" role for endometrial adenocarcino-
   ma, while  progesterone  is used for its treatment it appeared reasonable to explore this
   avenue of  research.

   b)  The goals set for the current period were to develop the methods  to study cytotoxici
   of chemical carcinogens (inhibition of DNA. synthesis)  and to study  the possible  regula-
   tory effect(s) of ovarian hormones.

   c)  Current and future  goals include the study of the effect of hormones on  the  uptake
   and binding of chemical carcinogens by radioautography and the "in  vivo" transformation
   of the cells.  All these studies are or will be performed in primary  cultures of rabbit
   endometrial cells.
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED rMedicaf.
   dental, etc.)

   Medical School
                                            SIGNATURE OF PRINCIPAL INVESTIGATOR
                                         FOR OFFICE USE ONLY
      SUPPORT METHOD fCfiecft <
Funds Estimate*
  I   $30,000
                                                  Dr.  George E. Stapleton
                                                  RESPONSIBLE ORGANIZATION
                                                  ERDA
76
     NO. OF FUTURE YEARS TENTATIVELY
     ASSURED BEYOND CURRENT F.Y,
                                                           STARTING DATE
7/76
Tuna's approximate not for Citation, 'ss AND SI-SIE 76A WHICH MAY NOT BE USED.
                                               190

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                        OMB No. liS-ROOSl
                                                              PROJECT NO. (Do not u«a ffila *pac«>
                                                              ssie
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                              EPA	
                                                              EPA-IAG-D6-E681-BAO
  Pulmonary Carcinogenesis  Test System
  IIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
  'ROFESSIONAC PERSONNEL ENGAGED IN THE PROJECT.

  R. J. Michael Fry,  Senior Physiologist
  W. E. Kisieleski, Chemist
  NAME ANO ADDRESS OF APPLICANT INSTITUTION
  Division of Biological and Medical  Research, Argonne National  Laboratory,
  9700  S.  Cass Avenue,  Argonne, Illinois  60439
  SUMMARY OF PROPOSED WORK - (1) Objective. (1) Approach. (3) Curmn Plant and/or Progress (200 words or leal.  Omit confidential data).
    In the Smithsonian Sc-tenee InfurmuliOA Eachange-, »ummerieB of work in progress are exchanged with government and private agencies aup-
  porting research and ure forwarded lo investigators who request such information. Your summery la to be ua*d tar these purposes.
        A number of biological active pollutants, in particular.polycyclic hydrocarbons,
  are  difficult to eliminate from the effluents of the various types of processing
  plants which,  are either now in use or are proposed.  Some of the polycyclic hydrocar-
  bons are known  pulmonary carcinogens but neither the precise nature of the effluent
  content nor the carcinogenicity of all of the identified compounds are known,- There-
  fore there is  a need for appropriate, rapid and economic methods of assay of the  on-
  cogenic-potential- of compounds and for the study of pulmonary tumorigenesis.
        The objectives are to:   (1) Establish appropriate  test systems for the assessment
  of tumorigenic  potential of compounds.  (2) Carry out the experiments in such a way
  that information  about the mechanisms of susceptibility including the relationship of
  proliferation is  obtained.  (3) Determine whether pulmonary carcinogens  act additively
  or multiplicatively in the mouse.
        The aims of  the current  work  are:  (1) to establish the spontaneous prevalence
  and  age-specific mortality rates of lung tumors in  BALB/c and C57B1/6 mice;  (2) to
  compare the tumorigenic effects of in vitro and in  vivo exposure to benzo(a)pyrene;
   (3)  to test-the use of-nude, athymic mice for transplants-of-lung tissue-from: different
  spe'cies in order  to compare species susceptibility" for  tumorigenesis.
        We have  established the  prevalence and mortality  rates for lung tumors  in male
  and  female B6CF,  and are currently completing the study of prevalence in the parent
  strains C57B1/6 and BALB/c.   It  should now be possible  to distinguish induction  and
  advancement of time of appearance  of tumors and whether carcinogens  act  additively.
  IDENTIFY PROFESSIONAL SCHOOL INVOLVED (ttettteal.
  i/rnfiij. ffr.)
                                           SIGNATURE OF PRINCIPAL I
                                                                               10/5^/76
     SUPPORT METHOD (C/u-cfc
                                        FOR OFFICE USE ONLY
                                       ~~       [PROJECT o
                                                   Dr. George D. Duda
                                                 RESPONSIBLE ORGANIZATION

                                                   ERDA	
Funds Estimate* F-v-
                  76
                       NO. OF FUTURE YEARS TENTATIVELY
                       ASSURED 9EYONO CURRENT F.Y.
Utl
   $83,000

     approximate not for citation.  .*' AND «-.* ^ «.,«, MAY MOT BE USED.
DATE
   7/76
                                             191

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                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
                                                                           Form Apprvt rj
                                                                          OMfl No.  /5S.-ROOS;
                                                                 PROJECT NO. fDa not ufte- thl* spvc

                                                                 SSIE
                                                                 __	

                                                                  EPA-IAG-D6-E681-BAQ
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                              or Tissue
   TITLE OF PROJECT Development of Method tor Utilizing I'eetn as an
                 Dose for Trace and Heavy Metals
   GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.                         .      .  .          , _ .  .  .
    Louis G. Stang,  Jr.,  Department of Applied  Science, Head, Radionuclide Research Division
    William Sachs, Department of Applied Science,  Associate Chemist,  100%
   NAME AND ADDRESS OF APPLICANT INSTITUTION
    Brookhaven National Laboratory
    (Associated  Universities, Inc.)
    Upton, New York  11973
                                          (T*i. L.  Sung - 516-345-4451})
   SUMMARY OF PROPOSED WORK- (!) Objectives, (2) Approsch. (3) Current Plan* and/or Progress (200 word* or less. Omit confidential data).
      In the Smithsonian Science Information Exchange, summaries of work in progress are eschanged with government and private agencies sup-
   porting research and are forwarded to investigators who request such information. Your summary ia to be used for these purposes.
   (1) Objectives:   To develop and demonstrate a simple rapid inexpensive method  for deter-
   mining  trace concentrations of toxic  energy-related elements  in  the human body.  To
   utilize  this method to establish "normal" baseline concentrations,  to search for causal
   relationships between concentrations  of  given elements and occupational, environmental,
   and individual health factors.  Background:   For many chemical elements little is known
   about what constitutes "normal" concentrations in the human body now or at various prior
   stages  of  industrialization or about  how these concentrations vary  with the individual or
   with intensity and duration of exposure.  Yet many of these elements have already been
   detected in the  environment and others are  likely to be added.   (2)   Approach:  Teeth,
   being ideal biopsy samples easily and readily available from  statistically large numbers
   of people, will  be analyzed for all elements  have Z>15 and the results will be statis-
   tically  analyzed in a search for correlations and trends.  (3)  Current Plans and/or
   Progress:   A report based on an exhaustive  survey of the literature on the trace element
   composition of hard dental tissues is in preparation.  This survey  tends to support the
   hypothesis, at least for some elements,  that  concentrations in teeth depend upon ambient
   environmental concentrations.  As a preliminary to chemical analyses of large numbers  of
   teeth that are being collected, data  on  trace element levels  in human enamel have been
   obtained from other sources and will  be  subjected to statistical pattern recognition
   analysis.   Ancillary nationwide data  on  trace element levels  in  soils, water supplies,
   and atmospheric  particulate matter are also being obtained from other sources  in order to
   provide material with which to attempt  to  correlate data on teeth.
   IDENTITY PROFESSIONAL SCHOOL INVOLVED (Me
   tfenfal, efc.)
                                                                      DATE
                                                                       11/9/76
                                        POR OFFICE USE ONLY
Funds Estimate*
    $55,000
          76
                                                 PROJECT OFFICER
                                                   Dr.  George D. Dud
                                                 RESPONSIBLE ORGANIZATION
                NO. OF" FUTURE YEARS TENTATIVELY
                ASSURED BEYOND CURRENT F.Y.
                                                   EROA
                                                  STARTING DATE
ESTIMATED COMPLETION
DATE
                                                                                July 1976
Funds approximate not for citation.
                                                          NOT BE USED.
                                               192

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        Form fyprnred
                                                                      O.HB No. /58-ROOS!
                                              PROJECT NO. (Do not use this space}

                                              SSIE
                                              __	

                                              EPA-IAG-D6-E681-BAO
The quantitative evaluation of hazardous chemicals  using a closed aquatic test  system
GIVE W AMpV flFP ARTMFN T^ a hi n n c Frn A t  TIT i ire n c- aaiki r-i a *i~~ i 1.1 jr^r- -i-i f 7^n'np An — "i.—~7^~—r _. _ _ _'.!!_''"' '' ' " ~	_ _ ~_~ ~
 IIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS ANO ALL OTHER
 'ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
      Setlow.  R. B., Senior Biophysicist, Biology Department    C^l. 314-3*5-3391)
      Hart, R. W.,  Consultant,  Assoc. Prof. Radiology, Ohio State University
 NAME AND ADDRESS OF APPLICANT INSTITUTION Biology  Department
                                    Brookhaven National Laboratory
                                    Associated Universities, Inc.
   	Upton, New York 11973	
 SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plai
                                                     • and/or Progress (200 words or less.  Omit confidential data).
     1)   To develop  a  new comparative  test  system,  using clones of the  fish ?oecilia
  formosa,  capable of  detecting the carcinogenicity of chemicals by treatment  of cells
  in vitro or by treatment of whole animals.
     2)   The fish P.  formosa may be grown in clones and hence there is  no  inmunological
  barrier to the transplantation of cells from one animal to another.   The fish are
  easily raised in  large numbers for comparatively low costs.  Past work has shown that
  if cells from thyroid tissue are treated  in vitro by UV radiation or  by  N-acetoxy-AAF
  and then injected  into isogenic recipients,  they give rise to large numbers  of
  invasive thyroid  carcinomas.  We have  reasonable dose response curves for  these effects
     3)   We propose  to test the carcinogenicity of a number of potentially hazardous
  agents associated  with coal and oil  shale technologies by 1) treating cells  in vlitro
  with the presumptive carcinogen, injecting the cells into fish and scoring the
  recipient fish for tumors one to two years later, and 2) to introduce the  presumptive
  carcinogens directly into the water  of fish tanks to assess their effects  on the
  whole animal.                                                          , ,     . *•
     The fish are maintained in water  purified by filtration and UV radiation  in an
  irradiator external  to the tank.  Under such conditions there is little  loss of animals
  from infection or  disease.  Fish were  injected with cells treated with BMBA  or with
  DMBA epoxide.  They will be killed and autopsied in the spring of 1977.
 IDENTIFY PROFESSIONAL SCHOOL I N VOL VEO r.Ve
 Jtvif.i/. etc. >
               NA
                                          ,tGNATUR£ C
                                                            Nov.  1,  1976
                                       FOR OFFICE USE ONLY
    SUPPORT METHOD (C/ict-fc oru-J
                               PROJECT OFFICER
                                 G.D. Duda
                                                RESPONSIBLE ORGANIZATION
                                                 ERDA
 FUNDS OBLIGATED
     75 K
F.Y.
 76
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
              1
1/76
                   7/77
 EPA F.™ 5760-1(7-72)    REPLACES PHS FORM ,S6 AND S.-I.I ^ WH,CH MAY NOT BE USEO.
                                          193

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                          Faint AfpnavJ
                                                        OMH No.
                                                               PROJECT NO. fOo mil use iMe mfme

                                                               SSIE
                                                               EPA~
                                                                 EPA-IAG-D6-E681-BAO
 TITLE OF PROJECT
 Quantitative Mutagenesis Testing in Mammalian CEllular Systems
 GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.

 Hatch, F.T., Principal Investigator,  Biomedical Sciences  Division
 Carver, J.H., Lead Scientist
 Branscomb, E.W.
 Galas, D.J.
 NAME AND ADDRESS OF APPLICANT INSTITUTION
 Lawrence Livermore  Laboratory
 P.O.  Box 808
 Livermore. Ca.  94550	
                                 Phone:     (415) 447-1100  ext 3563
 SUMMARY OF PROPOSED WORK - (1) Obleetlves. (2) Approach. (3) Current PUn. and/or Progress (200 word, or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work In progress are exchanged with government and private agencies sup-
 porting rssearch and are forwarded to investigators who request such Information. Your summary Is to be used for these purpose*.
      Objectives of this project are:   (1)   to develop  and apply quantitative multiple-
 marker assays utilizing cultured mammalian  cells for the  evaluation of potential muta-
 genic effects of-agents-derived from energy-technologies, and (2) to use these ex-
 isting and newly-developed biological  screening systemsHror .the;identlflcation-of-
 mutagenic agents associated with coal  and oil shale extraction,  conversion, or utiliza-
 tion.
      This program proposes the use of  multiple drug-resistance markersi.£or .forward
 mutation in cultured  Chinese hamster ovary  (CHO) cells, as  well as in vitro and host-
 mediated in_ vivo/in vitro procedures in the Syrian hamster  embryo (SHE) system.  The
 markers beTng developed measure the frequency of forward mutation at the recessive
 azaadenine-resistant  marker, the X-linked azaguanine-resistant phenotype, and  the dominant
 ouabain-resistant locus.   Established  procaryote and lower  eucaryote systems will be
 used for comparison and reference; the most- satisfactory-markers -in all. systems will
 then be combined into a standard protocol in which each of  the gene loci can be measured
 for mutation following exposure to a particular-test-agent.or combination thereof.
      Progress to date has been:   (1)   Selection and validation of three CHO cell lines
 heterozygous at the adenine phosphoribosyltransferase  locus.   These stock lines have
 been tested for optimal cell plating,  selecting drug-concentration, and expression time;
 the cell lines are now being used in triple marker mutagenesis experiments.   (2) The
 SHE system has been tested extensively-plating efficiency optimized, ouabain resistance
 determined, with work currently in progress to optimize the azaguanine-resistance marker
 Both CHO and SHE systems have been tested with the standard mutagen EMS, and experiments
 utilizing specific hydrocarbons relevant to energy technology are now underway.
 DENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
dental, ere.}

     NA
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
   SUPPORT METHOD fCttvek cmcj
    NEGOTIATED CONTRACT
FUNDS OBLIGATED
$100K
F.Y.

1976
                                      FOR OFFICE USE ONLY
                               #4
                                              PROJECT OFFICER
                                                 Dr. George D.  Duda
                                RESPONSIBLE ORGANIZATION
                                           AAES/ERDA
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
       Three
STARTING DATE
    June 1976
ESTIMATED COMPLETION
    June 1980
EPA Form 5760-1 (7-72)
                  REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                         194

-------
U.S. ENVIRONMENTAL PROTECTION AGENCY



 NOTICE OF RESEARCH PROJECT
                                                               PROJECT NO. fOo not i». ,1,1. awe*/
                                                               SIC
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                  EPA-IAG-D6-E681-BAO
 Development of Cytochemical Markers for  Cell Transformation  and Carcinogenesis
^r~V?«*i^?«?«^                       .NVEST.OATORS OR PROJECT DIRECTORS^ ALL OTHER
 Ma/all,  B.H., Principal  Investigator, Biomedical and Environmental Research Division
 Carver,  J.H.
 Jensen,  R.H.
 Dolbeare, F.A.
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Lawrence Livermore Laboratory
 P.O.  Box 808
 Livermore, Ca. 94550	
                                  Phone:  (415) 447-1100 ext.  3587
SUMMARY OF PROPOSED WORK - (1) Otj.cllv... (J) Approach, (3y Cu™« PI™, .nd/or Prop... (300 word. „ I.... Qmll confld.ntial <).,.)
   In th. SniithtofU.il Science Information Etchange, lummarie. of work In profraM an a.chanied with (ovtmn»nt and private .(encl.. .up-
portint re.aarch and arc forwarded to inve.llr.ator* who reqva.t >ueh Infc
                                                itlon. Yovr .ui
                                                           and private af.eni
                                            try la to be ua.d for theaa purpo.e..
      To develop rapid,  sensitive, and economical systems for the  in vitro and
 cytologieal-assay for carcinogenic effects .of substances Involved in-the.extraction,
 conversion and utilization of nonnuclear  energy sources, with particular consideration
 of in  situ coal gasification, shale-oil.utilization, .coal-burning power plants, and
 geothermal power plants.

      Our approach is based on the development of cytochemical markers for cell
 transformation, and on  our ability to quantitate such markers by  microfluorometry
 and by flow system analysis and sorting.  There are two phases to this work:  (a) the
 development of appropriate test systems whose response is defined by well characterized
 and representative carcinogenic agents,'and  (b) the application of  such systems to
 substances released by  energy technologies,  and including testing with whole and frac-
 tionated samples of effluents.

      The  intracellular levels of several hydrolytic enzymes have been chosen as  poten-
 tial early indicators of cell transformation.   Using synthetic fluorogenic enzyme sub-
 strates,  the  levels of four proteases and five  esterases -have been measured  on mono-
 layer cultures  of Chinese Hamster Ovary cells,  Syrian Hamster Embryo cells and Human
 Lung fibroblasts (both normal and viral transformed).   Hydrolase profiles generated
 from these measurements indicate significant differences between cell types.
      Flow cytometry analysis on  WI38  cells (normal  versus SV-40 transformed)  indicates
 that intracellular Cathepsin Bl  and Alkaline Phosphatase levels can be used  to dis-
 tinguish  individual normal cells from transformed cells.   These same enzyme  assays will
 be used to determine an optimum  in-vitro system for subsequent carcinogen treatment
 and flow  analysis.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.
DVnf'il. »-lr. )
 HA
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                            27/10/76
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD (Chock ono>
    RCSCARCH CMANT
                            TASK NO.



                                 #5
                                PROJECT OFFICER
                                  Dr.  George D.  Duda
                                RESPONSIBLE ORGANIZATION

                                 AAES/ERDA	
FUNDS OBLIGATED
 $32SK
F.Y.

 1976
                     NO. Of FUTURE YEARS TENTATIVELY
                     ASSURED BEYOND CURRENT F.Y.
STARTING DATE
   June 1975
ESTIMATED COMPLETION
°ATEJune 1980
EPA Perm 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT DE USED.
                                          195

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                         OAtfl Wo. VS-R0031
                                         PROJECT NO. (Do ml tit* IWa
                                         SSIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                 EPA-IAG-D6-E681-BAO
 TITLE OF PROJECT ^ALYSIS OF  THE EFFECTS OF ENERGY-RELATED TOXIC  JlAItiliALS iU
 STABILITY IN MAMMALIAN CELLS
 tl AP1L.J-1I  Li* 1UM l^U\J-i I.rt*T V^LjJ-ilj^
 OIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS Oft PROJECT DIRECTOR] AND ALL, OTHER
 PROFESSIONAL PERSONNEL ENCASED IN THE PROJECT.
 L. L. Deaven, Principal Investigator, Staff  Member, Cellular  and Molecular Biology Group

 Evelyn  W.  Campbell, Staff  Member, Cellular and  Molecular Biology Group

 latherine  Sanchez, Staff Member, Cellular ar.d Molecular Biology Group
 NAME AhO AD3RESS OF APPLICANT INSTITUTION
 Los  Alanos Scientific Laboratory. University of California, Health Division  (MS381),
 Los  Alamos, New Mexico   87545
    MARY OF ?=ICPOS£O WORK -  (I) OiJ«etl»... (I) A;;r3»eh, (J) Currrn: Plan, and/or Projt.j. (200 wordi or [..». Omll coittldtnllat dala).
   In th* Sai^senlaa Scicnc* InTerr'jtloii Excti»itf*v *u£saar:r» of work in prefrnft »r* vzchanfvd with cevvmrnvnt and prlvati «f«net«« cup.
       »**r?^ and *r» ^orward«d to invntlcator* who r*^-j«al such Information. Yatr suaaary ia to b* uaad for thaaa purp«a*«*

 The objectives of this  program are to develop systems for  the rapid detection of  kary-
 otypic changes in mananalian cells as a result of exposure  to energy-related environmental
 pollutants and to screen selected subjects  utilizing these systems.  Flow microfluorometry
 (FMF)  of isolated, fluorescently stained chromosomes will  be used  to identify chromosome
 aberrations, and FKF  of stained intact cells will be used  to detect mitotic nondisjunc-
 tion.   Cadmium will be  used as the clastogenic agent in the development of a test system.
 He have demonstrated  that chromosome analysis can be accomplished  by flow systems in
 mammalian cells with  relatively simple karyotypes (Chinese hamster 2N = 22).  Cadmium at
 low concentrations  (2 x 10~° M) is a potent clastogen.  It induces primarily chronatid-
 ype aberrations.  We have also demonstrated that tolerance to  the damaging effects  of
 cadmium can be induced  in fibroblasc cells  in culture by long-term exposure of the cells
 to sublethal concentrations  (2 x 10   M)  of cadmium.  We plan to repeat these experiments
 on human fibroblast and lymphocyte cells  in vitro and to extend these studies to  other
 toxic agents associated with alternative energy  technologies.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED f.V
                                            STATURE OF" Phv4C.pX.L-\NVeSTlGATOB
                                                    — W
                                                                                  11-24-76
                                       FOR OFFICE
    SUPPORT METHOD rCArcfc onrl
                                                 Dr.  George  D.  Du-ia
                                                 ERDA
 Funds Estimate-*"-
  $50,000    I 76
NO. OF FUTURE V£AC»S TENTATIVELY
ASSURED DETONO CUlinCNT F.Y.
                                   STARTING DATE
ESTIMATED COM
j'ily  1976
7Funds approximate not for citation t ANO SI-SIE VISA «HICH HAY NOT BE USED.
                                              196

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                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
                                                                           Form Approved
                                                                          OMB No.  V8-R0081
                                                                PROJECT NO. (Do not use this ,
                                                                iSlE
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                EPA-IAG-D6-E681-BAO
  SOMATIC CELL GENETICS
  GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
  PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.                             uint<-runs AND ALL OTHER
  S. J.  Barnhart,  Staff Member,  Cellular and Molecular Biology Group (H-9)

  I. T.  Okinaka, Staff Member,  Cellular and Molecular Biology  Group (H-9)

  S. H.  Cox, Staff Member,  Cellular and Molecular Biology Group (H-9)
  NAME AND ADDRESS Of APPLICANT INSTITUTION
  •os  Alaaos Scientific Laboratory. University of California
  ?ost Office Box 1663
    s  Alarms, New Mexico   87545
  SUMMARY OF PROPOSED WORK - (I) Objectives. (2) Approach. (3) Current Plans and/or Progress (200 words or leu. Omit confidential data).
    In the STajshsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
  porting research and are forwarded to- investigators who request such information. Your summary is to be used for these purposes.
  Che  genetics  program is  currently isolating temperature-sensitive (ts) mutants (variants)
  of the mammalian cell lines CHO and DON  CCL for use  in studying the  genetics of cell
  life-cycle traverse.  In addition to  these ts mutants, we have isolated  several auxo-
  trophic ^clones  and have  developed the HGPRT+ * HGPRT- mutation system  for  use in assess-
  ing  the mutagenicity of  suspected carcinogens derived primarily from coal  gasification
  and  shale extraction processes.^  The  Ames Salmonella/microsome test  system will serve
  as an ancillary test for mutagenicity.   The mammalian cell forward and reverse muta-
  tion systems  and the Ames bacterial test system are  currently functional in this Labor-
  atory.  Temperature-sensitive life-cycle traverse mutants are being  analyzed to deter-
  mine in what  phase of the life cycle  the ts phenotype is expressed using the LASL flow
  microfluorometer (FMF II) .
  IDENTIFY PROFESSIONAL SCHOOL INVOLVED Oferf/ca/
  dfiitol, e:c.)
     SUPPORT METHOD Check one.)
      RESEARCH.G
Funds Estimate?! F.Y
                                                 PROJECT OFFICER
                                                :3r. George D.  Duda
                                  6&7
                                                  RESPONSIBLE ORGANIZATION

                                                  ERDA      	
|$100, 000
                  .
                 76
                        NO OF FUTURE Y = »HS TENTATIVELY
                        ASSURED BEYOND CURRENT F.Y.
                                                          STARTING DATE
                                                           1975
DATE   1977
        approximate not for citation.s» ANOSI-SH
                                                        MAY NOT BE USED.
                                                    197

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form Afptxitd
                                                                       0.118/Va. IJJ-SOOS/
                                     PROJECT NO. (Oo not uao U»« ap««J
                                     SHE
                                     EPA	
                                     EPA-IAG-D6-E681-BAO
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
DETECTION OF EARLY CHANGES IK LUNG CELL CYTOLOGY BY FLOW-SYSTEMS  ANALYSIS TECHNIQUES
 DIVE NAVES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 J.  A.  Steinkamp, Principal Investigator, Staff Member, Biophysics and Instrumentation Grou
 G.  C.  Salzman, Staff Member, Biophysics and Instrumentation  Group
 M.  Ingram, Staff Member, Biophysics and Instrumentation Group
 K.  M.  Hansen, Staff Member,  Biophysics and Instrumentation Group
 J.  S.  Vilson. Staff Member. Mammalian Biology Group	
 HAMS AN3 A 3 S a ESS OF APPLICANT INSTITUTION
 Los Alasos Scientific Laboratory,  University of California, Health Division 015881),
 Los Alanos, Sew Mexico  87545
 SUMMARr OF P339OSEO WORK- (1) Osjactivaa. (2) A;;r3«!i. (J) Cumnt Plan, .ad/or Prai»»»  «r It>l. Omit canfUanlial dau).
   fa eh* Sai:^»c=*iaa Sciinca bi/onsation Exehanfa. lu==^rits of wark in ?raa.re»» arv rxchangad with cavimmant and prlvala agcndaa tup*
 porting rv*«*rc^ aid aj-v forwardad to Invaatlfators who rvq-j*ll tuca In/oreiation. Yaur aitmma/y ll to ba uacd (of thas* pwpoaaa.
      The objective of this health effects program is the application  of  modern automated
 cytology techniques for  assessment of damage to human  populations  resulting from exposure
 to physical and chemical agents  associated with oil shale  and coal extraction, conversion,
 and utilization.  The approach is to apply unique flow-system cell-analysis and sorting
 technologies developed at the Los Alamos Scientific Laboratory  to  determine cytological
 and biochemical indicators of early atypical changes in  exposed lung  epithelium using the
 Syrian hamster initially..as  a model test system.  The  current plans are  to  adapt cell
 preparation and staining methods developed for flow systems  to  characterize lung cells
 from normal and exposed  hamsters using the multiparameter  cell  separator  and multiangle
 light-scatter systems.   Thi^ includes acquisition of respiratory cells by lavaging the
 lungs with saline, adapting  cytological techniques developed on human gynecological
 specimens to hamster lung epithelium for obtaining single-cell  suspensions, utilization
 of existing staining techniques  for measurement of cellular  biochemical  properties, and
 initial characterization of  lung cells using flow analysis instrumentation.  Progress
 has been achieved in measuring DNA content, total protein, esterase activity, cell size,
 nuclear and cytoplasmic  diameters, and multiangle light-scatter properties  of exfoliated
 hamster lung cell samples composed of macrophages, leukocytes,  epithelial,  and columnar
 cells.  As this new technology is adapted further to analyze lung  cells  from hamsters and
 subsequent characterization  studies are completed, measurement  of  changes in physical and
 biochemical cell properties  as a function of exposure  to toxic agents associated with
 synthetic fuel energy production will be performed, with eventual  examination of sputum
 samples from occupationally  exposed humans.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED MrrfiCJl.   SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                                11-24-76
                                       FOR OFFICE USE ONLY
    SUPPORT METHOD rC^ee^ am,)
    •GCNC* »T A
                                               PROJECT OFFICER
                                               Dr. George D.
                                               RESPONSIBLE ORGANIZATION
                                                EREA
 Funds Estimate**-
   $50,000    |  76
REO BEVONO CURRENT F.Y.
                               STARTING DATE
ESTIMATED COMPLETION
DATE
July 1976
'funds approximate not for citation.   AND SI-SIE T«A WHICH MAT NOT as USED.
                                            198

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                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
                                                                            Form Approved
                                                                          OMB No. DS-ROOS1
                                                                  PROJECT NO. (Do not use tnls spacej
                                                                  SSIE
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                    EPA-IAG-D6-ES81- BAO
    ITLE OF PROJECT
        Development  of Permanent Epithelial Cell Lines
    IVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
    ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

         J.  Selkirk
         Biology Division
   NAME AND ADDRESS OF APPLICANT INSTITUTION
         Oak Ridge National Laboratory
         P. 0. Box X
         Oak Ridge,  IN  37830.
   IUMMARY OF PROPOSED WORK * (I) Objectives. (2) Approach. (3) Current Plans and/or Progress 1200 words or lass. Omit confidential data).
     In llw Smilhsonlnn Seiencr Information Exchange, summaries of work in DTOETSSS are exchanged with government and private agencies eup-
   >orling research find are forwarded to investigators who request such information. Your summary is to be uaad for these purposes.

      Objectives:   (l) To develop the means by which chemicals associated with non-nuclear
      energy  generation,  especially agents  arising from coal and oil shale  extraction, can
      be screened for potential carcinogenic activity reliably, quickly  and cheaply
      relative  to current animal exposure  techniques; (2)  To utilize appropriate cultured
      cells  developed in (l) for the study of hydrocarbon  carcinogen metabolism to active
      forms  and the mechanism of chemical  carcinogenes is.

      Approach-  A research  group with  two discrete but closely related  approaches to
      these  problems is  being developed.   These  are  (1) Cell Biology.  The  major focus
      here will be the development  of permanent  cell lines of epithelial origin (human,
      when possible and  appropriate) which possess the  enzymatic equipment  for carcinogen
      activation  and which  are transformable with high  frequency.  (2) Biochemistry.
      Principal focus will be the study of metabolism of polycyclic hydrocarbons in
      various cell lines developed  in approach (l), to  establish with  certainty the
      "ultimate"  carcinogenic metabolite,  using  primarily high pressure  liquid
      chromatography techniques.
    IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Hi;llcul.
     i'»l. ,-rr.)
                         H/A
                                                          \
                                                                                 10/8/76
                                          FOR OFFICE USE ONLY!
       SUPPORT METHOD fO"-rft ""'•'
                                                     DrErGeorge D.  Duda
                                                   RESPONSIBLE ORGANIZATION
                                                     ERDA        	
Funds' Estimate*
                    76
   I  $60,000
%unds approximate not f
-------
                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                         OMB No. 158-ROOS/
                                                                PROJECT NO. (Do not u«e thin fpmc

                                                                SHE.
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
   TITLE OF PROJECT
   	f!mviari.j.nfj fnr> tfra Mutagani.n.-tiJ  rrnd. dnpci.nonen-ia-lty of Energy Related Pollutants
   GIVE NAMES. DEPARTMENTS, ANO OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
         A.  «.  Hsie
         Biology Division
   NAME AND ADDRESS OF APPLICANT INSTITUTION
          Oak Ridge national.Laboratory
          P. 0.  Box X
          Oak Ridae. TN  37830	
   SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach. (3) Current Plan* and/or Progrves (200 word! or !e»». Omit confidential data).
      In Ihr Smithsonian Scirnc*1 Itiforrnution Exchange, summaries of work In progress are exchanged with government- and private agencle* sup-
   Our major  efforts have concerned dose-response studies of  benzo(a)pyrene (ITalP)  and its
   metabolites on the'mutagenicity (as  measured by 6-thioguanine resistance) and cytotoxi-
   city  (as measured by single cell  survival) in the Chinese  hamster ovary  (CHO) system
    [Hsie et al. (1975) Som. Cell  Gen. J_,  2^7].  We have chosen  to study B(a)P as a model
   environmental agent because polycyclic hydrocarbons such as  B(a)P are major nonnuclear
   energy  related pollutants especially of coal-related energy  processes such as COED Coal-
   Liquifaction ("Syncrude").  B(a)P requires metabolic activation  by mixed-function
   oxidases to convert 3 (a) P into  active metabolites.  Since CHO cells do not contain appre-
   ciable  microsomal activation activity to metabolize B(a)P,  the direct biological  activi-
   ty of its  metabolites can thus be studied quantitatively.  The cytotoxicity and muta-
   genicity of 6-phenols (1-, 2-, 3-,  7-, 8- and 9-hydroxylbenzo[a]pyrene), trans-7,8-di-
   hydroxyB(a)P-7,8-diol (B[a]P-7,8-diol), l»,5-dihydroxyB[a]P-4,5-epoxide  and  B(a)P-9,10-
   epoxide have been tested.  B[a]P-7,8-diol and B[a]P-4,5-epoxide are highly mutagenic as
    their mutagenicity can  be detected as low as 2.5 ug/ml  (approximately 5 to  6-fold over
    the spontaneous frequency).  While all 6 phenolic derivatives of B[a]P  are  nonmutagenic
    they are all cytotoxic  with  7-hydroxyB[a]P being the  least toxic while  8-hydroxyB[a]P
    exerts  the highest toxicity.   B[a]P-9,10-epoxide is both  non-toxic and  non-mutagenic up
    to 20 ug/ml  tested.  Additional dose-response studies  are  underway to quantitate  the
    cytotoxicity and mutagenicity  of these and other B[a]P  metabolites.  Our study  shows
    that 7,8-diol and  ^.S-epoxide  derivatives of B[a]P are  powerful  mutagens.   Since  most
    carcinogenic polycyclic hydrocarbons are mutagenic,  it  is  likely that  these diol  and
    epoxide derivatives are the  ultimate carcinogenic metabolites of B[a]P. We have  just
    started screening  for the mutagenicity of various fractions from synthetic  fuel  process
    in this mammalian  cell  mutational assay.  Meanwhile,  efforts  to establish a sensitive
    and quantitative  in vitro mammalian cell  transformation assay are being continued.
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Mrtlic.it,
   ili-nt.il, ,.r,-.l

      N/A
                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                  A. W. Hsie
                                                          DATE
                                                          10/11/76
                                         FOR OFFICE USE ONLY
      SUPPORT METHOD (C/i,-rfc .,11
Funds Estimate*
   |$80,000
                                                 PROJECT OFFICER
                                                 Dr. George D.  Duda
                                                 RESPONSIBLE ORGANIZATION
                                                 ERDA
76
                                       STARTING OATE
ESTIMATED COMPLETION
DATE
  July 1976
'Funds approximate not for citation. ,66 AND S,.S1E 76A WHICM MAV NOT 8E USED.
                                               200

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                         OMB No. W-ROOSJ
                                                           PROJECT NO. (Da not use Hlls spaca)

                                                           SSIE
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                 EPA-IAG-D6-E681-BAO
  TITLE OF PROJECT                                     	;	—	'      ___^.^__
  Evaluation of the Turnorigenie Enhancing  Potential/o'f TOJyxyclic Aromatic Hydrocarbons
  OWE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
  PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.

  Carl Peraino, Biochemist
  R. J. Michael Fry,  Senior Physiologist
  IAME ANO ADDRESS OF APPLICANT INSTITUTION
  Division of Biological and Medical  Research, Argonne  National Laboratory,
  9700  S.  Cass Avenue,  Argonne, Illinois 60439
  SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Currant Plans and/or Progress (200 words or less. Omit confidential data).
    In Ihr Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
  porting research and are forwarded lo investigators who request such information. Your summary Is to be us«d for these purposes.

        Our studies have  shown that  dietary phenobarbital enhances hepatic tumorigenesis
  in rats previously  fed the liver  carcinogen 2-acetylaminofluorene  (AAF).   This sequen-
  tial treatment procedure-has proven-useful as  a.means  of detecting tumorigenic en-
  hancers in the environment, and has  shown that the  insecticide, DDT,  and-the  food
  antioxidant, butylated hydroxytoluene^ possess enhancing activity, - The objective of
  the  present work is to use the sequential treatment protocol to test  the tumorigenic
  enhancing activity  of  the polycyclic aromatic  hydrocarbon benz(a)anthracene,  which
  serves  as a model for  energy-related pollutants.  The  approach used involves  the short-
  term feeding of AAF followed by the  feeding of the  test hydrocarbon.   Increased tumor
  incidence in this group in comparison with that in  rats receiving AAF or the  hydrocarbon
  alone denotes  enhancement.
        Since the study is still  in  progress final conclusions are not yet possible.
  However, on the basis  of the data obtained thus far,  0.025% dietary benz(a)anthracene
  appears to exhibit  little or no tumorigenic enhancing  activity.   Since acute  exposure
  studies indicated that benz"(a) anthracene-is, like phenobarbital,-: an effective-stimu-
  lator of liver growth  and microsomal enzyme activity,  additional  dietary  studies at
  higher dose levels  may be necessary  to permit  the unequivocal  evaluation  of the tumori-
  genic enhancing potential of this hydrocarbon.
  IDENTIFY PROFESSIONAL SCHOOL INVOLVED nird/r.,1,
  th'tttat, t'lr.)
                                                                                       '2L.
                                        FOR OFFICE USE ONLY
SUPPORT METHOD rC/irrk (Xt.0
Funds Estimate'*
 r$52, 000
             76
                                       10
                                                 PROJECT OFFICER
                                                 Dr.  George D.. Duda
                                            RESPONSIBLE ORGANIZATION

                                             ERDA
                   NO. OF FUTURE YEARS TENTATIVELY
                   ASSURED BEYOND CURRENT F.Y.
STARTING DATE
  June 1975
ESTIMATED COMPLET
D*Tnne 1980
       approximate not for Citation. >« »«° *<-** «» WHICH MAY NOT BE USED.
                                          201

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          Form Approved
                                                                        OMB No. 1H-R0081
                                                               PROJECT NO. (Do not use f/iix apace)

                                                               SSIE
                                                               EPA
                                                                    EPA-IAG-D6-E681-BAO
  A^Bacteriaphage System for Screening of Carcinogenic Polycyclic Aromatic  Hydrocarbons
  GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS ANO ALL OTHER
  PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
  Dr.  Samuel B. Weiss,

  Dr.  Wen-Tali Hsu,
        Associate Director of IOT
        Professor of Biochemistry and Microbiology
        Assistant Professor of Biochemistry
        Research Associate of the FMI
  ^ieE l^ank^i"sl?cI«PSl^norla£u5esearch Institute
  The University of Chicago
  950 East 59th Street, Chicago,  Illinois 60637
  SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach. (3) Current Pl»n» and/or Progress (200 words or loci. Omit confidential dat»).
     In the Smithsonian Science Information Exchange, summaries of tvork in progress are exchanged with government and private agencies •uo-
  portlng research and are forwarded to investigators who request such Information. Your summary Is to be used for these purposes.
      The use of bacterial viruses as a means for detecting potentially harmful
  substances stems from earlier studies in this laboratory which demonstrated that certain
  hydrocarbons known to be carcinogenic in rats also inhibit the replication of
  bacterial viruses.  We have  now confirmed the above  findings by examining  some 30
  different hydrocarbons and their derivatives and have  shorn that compounds, which are
  either  known to be strong alkylating agents, or ones which can be converted into
  alkylating agents by the action of intracellular enzymes, block phage replication.
  We propose to fcse the infectious-nucelic acid system to  examine other potentially
  toxic substances, however, we are also interested in determining the biochemical
  mechanism by which these reactive hydrocarbons block the expression of  genetic in
  formation.
      We  propose to devise several different in vitro  systems to examine  the effect of
  active  hydrocarbons on the process of transcription  and  translation.  We should .like
  to obtain answers to the following kinds of questions,  l)  Does the binding  of
  hydrocarbons to DKft, and RKA.  affect the template activity of these nucleic  adids with
  respect to DNA and RHA synthesis,  and if so, in which  way; e.g., is the efficiency of
  synthesis  reduced, are errors in base Insertions made, etc.  2) Do active  hydrocarbons
  bind  to DNA. and RHA polymerases, and if so, how do such  altered enzymes differ in
  their enzymatic properties.   3)   Can bydrocarbon-RHA complexes serve as templates for
  protein synthesis; if so, are the  proteins made the  same or different from nonconrplexed
  templates.  !»•)  What is the  effect on protein synthesis  when ribosomes  are reacted
  with  active hydrocarbons.
      Answers to the above questions should help in understanding how these  potent
  chemical agents (the aromatic hydrocarbons) may influence several important
  biological processes within  the cell.
  IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
     ul. t-ic.)
                                          SIGNATI^HE OF PRINCIPAL 1NVESTIGATOF/     DATE
     SUPPORT METHOD r'CJrvcA-
      RESEARCH GRANT
Funds Estimate*'F-Y-
    $52,000
76
                                       FOR OFFICE USE ONLY
            TASK .NO.

                  10
                                                PROJECT OFFICER
                                                  Dr. George D.  Duda
                               RESPONSIBLE ORGANIZATION

                              I  ERDA
                       NO. OF FUTURE YEARS TENTATIVELY
                       ASSURED BEYOND CURRENT F.Y,
                                                         STARTING DATC
ESTIMATED COMPLETION
"July  1976
 Funds approximate not for Citation, ss AND SI-SIE 76A WHICH MAY NOT BE USED.
                                               202

-------
                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
                                                                            Form Approved
                                                                          OMB No. ISS-ROOS1
                                         PROJECT NO. (Do not uae Ihl. spacej

                                         5SIE
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                     EPA-IAG-D6-E-681-BAO
   DEVELOPMENT AND USE OF DIFFERENTIATED CELL CULTURES FOR EVALUATION OF TOXICOLOGICAL AGEI CS
   GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   Principal Investigator:  L.E. Gerschenson
   Co-Investigators:         J. da  Vellis, I. Harary, H. Herschman, L. Lake and J. Berliner
   NAME AND ADDRESS OF APPLICANT INSTITUTION
   Laboratory of Nuclear Medicine and Radiation Biology; Univ. of Calif, at Los Angela*
   900 Veteran Avenue, Los Angeles,  California  90024
   SUMMARY OF PROPOSED WORK - (I) objectives. (2) Approach, (3) Curr.nl Plan, and/or Progress (200 word, or 1«... Omit confidential dam).
      In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
                                 itors who request such information. Your summary Is to be used for these purposes.
          The aim of this project is to study  the molecular mechanism(s) of acute  toxicity
    in differentiated liver, muscle and brain  permanent cell  lines.   For this purpose the
    effect of lead  upon the heme  pathway and the organ-specific  functions of the cell lines
    is under investigation.  We propose to validate these in  vitro  models as rapid,
    simple and reliable systems to screen for  energy-related  pollutants.

          Lead was  found to:  a)  modulate the  levels of the 'enzymes   ^ -aminolevulinate
    synthetase and  aminolevulinate dehydrd^tase in cultured liver cell lines;  b) have no
    effect on the induction by glucocorticoids of the enzyme  tyrosine-aminotransferase in
    the same cell line;  c) inhibit the induction of glycerpphosphate dehydrogenase by
    glucorcorticoidSin cultured glial cells and the content of the specific  protein  S-100;
    d) inhibit myogenesis in cultured muscle cells  and e) Induce mitochondrial damage
    (E.M. studies)  in liver and gllal cell lines.
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
   dental, etc.)
     UCLA School  of Medicine
                                            SIGNATURE OF PRINCIPAL INVESTIGATOR
                                          FOR OFFICE USE ONLY
      SUPPORT METHOD (Check one)
                                     12
                                                   PROJECT OFFICER
                                                   Dr.  George D.  Duda
                                                   RESPONSIBLE ORGANIZATION
 Funds Estimate* F-Y-
     $100,000     76
NO. OF FUTURE YEARS TENTATIVELY
ASSURED 8EYOND CURRENT F.Y.
                                                            STARTING DATE
ESTIMATED COMPLETI
DATE
  July 1976
*Funds approximate not for Citation, us AND SI-SIE 7.A WHICH MAY NOT BE USED.
                                              203

-------
                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
   TITLE OF PROJECT
      Therapy of Non-radioactive Toxic Metal Compounds
                                                                          Form Approved
                                                                         OMB No.  D8-R0081
                                                                PROJECT NO. fDo not uae rhia «pac

                                                                SSIE
                                              EPA
                                               EPA-IAG-D6-E681-BAP
   GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
      A. Lindenbaum, Biochemist,  Principal Investigator.
      D. W. Baxter, Research Associate (Summer  1975);  N.  G.  Doan. Student  Aide (Summer 1975)
      E. M. Sorensen, Postdoctoral  Appointee; V. L. Riotte,  Student Associate (Fall 1976).
        [All above in Division  of Biological and Medical  Research.]
   NAME AND ADDRESS OF APPLICANT INSTITUTION
      Argonne National Laboratory
      9700 So. Cass Avenue
      Argonne, IL  60439
   SUMMARY OF PROPOSED WORK - (1) Objective.. (2) Approach. (3) Curr.nl Plan, .rid/or Pro(reaa (200 word, or I.... Omit confidential data).
      In the SmUhaonlan Science Information Exchange, summaries of work in progress are exchanged with government and private agenciea •up-
   porting research and are forwarded to investigatora who request auch information. Your summary Is to be usvd for theae purpoaaa.

           The hazard to man  represented by many toxic metals of environmental concern
      (e.g., Pb, As, Cd, Hg)  depends upon the extent to which they become concentrated and
      retained in  critical compartments of living  tissues.  By measuring  the  degree-to
      which a metal will undergo hydrolysis,  protein binding, and/or incorporation within"
      cells in selected animal  species, the critical parameters necessary to  devise
      effective therapeutic measures may be determined.  The basic objectives of this work,
      therefore, are to identify and measure critical  concentrations of toxic metals  in
      organs, cells, and subcellular organelles  of mammalian species and  to devise thera-
      peutic procedures for reducing these concentrations to acceptable levels.

           For two reasons, initial efforts are  concerned with lead..-First,  lead is  one
      of the most  ubiquitous  of environmental pollutants.  Second, some of our recent work
      on actinide  decorporation may offer a direct therapeutic application in the case of
      lead poisoning.  Our first studies demonstrated  differences in the  deposition of lead
      acetate and  lead citrate in mouse tissues  (D. W. Baxter et^ al^.,  Proc. 15th Ann.
      Hanford.Life .Symposium,  in press,-1976),--Present, plans Include  the treatment-^of,
      young mice,; having- a specific-,-well-established  burderrof- stable -lead" coritaining-
      lead-210 tracer.with DTPA and DTPA esters.   Quantitative measurements will be made
      of the tissue distribution of 210Pb, using y-ray spectrometry, and  of the cellular
      localization of stable  lead,  using energy  dispersive X-ray spectrometry.  In addition,
      using optical and electron microscopy, we  will undertake morphometric analyses  of
      cellular and ultrastructural changes in the  brain, kidney, gut wall, and liver  during
      therapy.  These data should provide useful information in determining therapy
      regimens resulting in maximal lead removal with  minimal tissue damage.
   IDENTIFY PROFESSrONAL SCHOOL INVOLVED Wed/car,
   denfai, etc.)
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
      SUPPORT METHOD (Check onej
 Funds Estimate*-
  [$111,000
76
                                        FOR OFFICE USE ONLY
                                                 PROJECT OFFICER
                                                 Dr. Murray Schulman
                                                 RESPONSIBLE ORGANIZATION
                                                  ERDA
       NO. OF FUTURE YEARS TENTATIVELY
       ASSURED BEYOND CURRENT F.Y.
                                        STARTING DATE
ESTIMATED COMPLETION
DATE
                                                             July 1976
''"Funds approximate not for Citation, iss AND SI-SIE 7SA »HICH MAY NOT BE USED.
                                             204

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                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          Form Approved
                                                                         OMB No. 158-R0081
                                               PROJECT NO. (Do no. u. ,1,1,

                                               SSIE
                                                                     EPA-IAG-D6-E-681-BAP
      Influence of Diet  on the Gastrointestinal Absorption of  Cadmium
      ~"-*~"""*^~ ~-~ »^^w  v.» ....*/ m^.J »-A *s J.JH,XJ .J V A**tfcA f\L? JVJ. fr* 1.-LIMJ ^.L  VidmlLLLUU

  GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
  PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
     H.  E.  Walburg, Director (Principal  Investigator)
     UT-CARL
     Oak Ridge, Tennessee  37830
      (615)  483-8611, Ext.  3-4205
                                            R. J. Chertok, Assoc.  Prof.
                                            L. B. Sasser, Asst.  Prof.
  NAME AND ADDRESS OF APPLICANT INSTITUTION
      University of Tennessee Comparative Animal Research Laboratory
      1299 Bethel Valley Road
      Oak Ridge, Tennessee  37830
  SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
     In tht' Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
  porting research and are forwarded to investigators who request such information. Your summary Is to be used for these purposes.
  This  program is  a comparative study  of the influence of nutrient composition on the  gas-
  trointestinal absorption of Cd.   The absorption of Cd  occurs  in competition with the ab-
  sorption of specific  essential nutrients  which accounts in part for the variable absorp-
  tion  characteristics  of Cd and could also determine the degree  and mode of toxicity.

  Animals maintained  on diets modified with Ca,  P, vitamin  D or protein are orally admin-
  istered small to moderate doses of 115raCd.   Absorption is determined by serially sac-
  rificing the animals  and analyzing for radioactivity.

  In vitro studies in the rat utilizing the everted sac  technique are being conducted  to
  determine (1) the kinetics of Cd  absorption,  (2) the effects  of nutrient constituents on
  Cd absorption and  (3) the effects of Cd on the absorption of  various nutrients such  as
  Ca, Fe, amino acids and sugars.
  In addition studies will be conducted to  determine the location of Cd within the gastro-
  intestinal epithelial cells and the  effects of Cd on cell metabolism by measuring
  changes in enzymatic  activity.
  Mature male rats were pretreated  for 4 weeks with diets containing (1)  adequate Ca and
  P, (2) low Ca and P,  (3) high Ca  and P, (4) high Ca and low P and (5) low Ca and high
  P. Rats from each- diet were orally dosed with 10 uCi  of  Cd-115 m in solutions contain-
  ing either 0, 5  or  25 mg of stable Cd. Preliminary results indicate that Cd absorption
  was increased in the  high Cd dose by a wide Ca:P ratio or by  diets high in both Ca and
  P. When both Ca and  P levels were low, Cd absorption  was not affected.  Cadmium toxi-
  city  appeared to be much greater  in  rats  receiving high Ca and  low P diets.

  The everted sac  studies are in progress and kinetic data  on tissue uptake and the  lumen
  to serosa transfer  of Cd are being collected and subjected to analysis.
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED (ML-tlic.il.
   
                N/A
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
                                        FOR OFFICE USE ONLY
     SUPPORT METHOD
      AGENCY STAFF (
Funds Estimate*
  I $90,000
                                                 PROJECT OFFICER
                                                      Murray  SchulmarL
                                                 RESPONSIBLE ORGANIZATION

                                                 ERDA
76
NO OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                                                            DATE
                                                             July 1976
*Funds approximate not for citation, a AND SI-SIE ?6A WHICH MAY NOT BE USED.
                                               205

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                            Fttfm Approved
                                                          OMI No. HH-KOOgl
                                                                PROJECT NO. (Da not uae (Ma ap>»>
                                                                ssie
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                   EPA-IAG-D6 -E681-BAQ
TITLE OF PROJECT
 The Mouse Oocyte  System as a Monitor of Chemical Toxicity
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
 Dobson,  R.L., Principal Investigator, Biomedical Sciences Division
 Felton,  J.S.
 Kwan,  T.C.
 Wuebbles, B.J.
NAME ANO ADDRESS OF APPLICANT INSTITUTION
 Lawrence Livermore  Laboratory
 P.O.  BOx 808
 Livermore, California 94550
                        Phone:
                                              447-1100 ext. 3557
SUMMARY OF PROPOSED WORK - (I) Objective!. (2) Approach. (3) Currant Plant and/or PTOJT... (300 word* or !••>. Omit confidential data).
   In the SmUhmonlan Science Information Exchange, sumraarlee of work In proereaa are exchanged with government and private afonclea aup-
porting research end are forwarded to InveallfBtorft who request euch Information.  Your eummary la to be used for theae purpoaea.
       This research-project is directed at..measuring effects produced in the  intact
 mammal by exposure  to chemical pollutants.   Effects are--measured  at the cell pop-
 ulation level, in vivo.   Focus is  on evaluating the teratogenic cytotoxicity of
 hydrocarbons and metals- associated with nonnuclear energy production.   Ovarian
 oocytes of developing mice are the cell'population studied.  Selected  chemical  agents
 are administered to groups of mice,  each agent in several differing concentrations.
 Administration is by way of the pregnant mother during  gestation  and to offspring
 postnatally.  Biochemical procedures and chemical assays  are done as required to
 provide necessary quantitative dosimetry information.   After exposure, surviving
 oocytes are enumerated microscopically in ovaries and compared to unexposed controls.
 In this way quantitative dose-response curves  are obtained.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.
tlfntal, rlc.J
 NA
                                          IGNATQRE O
                                                              VESTPGATOR
                                                                                27/10/76
                                       FOR OFFICE USE ONLY  \
   SUPPORT METHOD (Check one)
                                                PROJECT OFFJCER
                                                 Dr.  Dean R. Parker
                                                RESPONSIBLE ORGANIZATION
                                                   AAES/ERDA
FUNDS OBLIGATED
 $75K
 F.Y.

1976
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.

  Three
STARTING DATE

   June 1975
                                                                                June  1980
EfA Form 5760-1 (7-72)    REPLACES PHS FORM 166 ANO SI-SIE 7SA WHICH MAY NOT BE USED.
                                            206

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                            PUttLlC HEALTH Sf »]VICC
                          RESEARCH OBJECTIVES                 EPA-IAG-D6-E681-BAQ
                                                                    :- n M.V:-£ h
   Stanford Research  Insti l-.i tc,  333 Rnvcnsvond Avenue,  Mcnlo p.-.r!;,  California   C-;025
NATT.~c7ATr!a^iTT7n;T^r?ror7£^
pnojr.cT. LLGi'iMNu WITH PIIVCI?AL iMvr
   A. D. Mitchell  (^,39-G2-S7SG)  Principal Invostifiator. Cell Biologist,  Bior.c-dical
        Dcyartr.cnt
   K. Stelos  (452-GS-71TD5  Postdoctoral Fellow in Cell Biology,  Bio-edical  r.e
        Department
   M. V. McMacke'n  C5S3-09-4277)  Biochemist, Biomedical Research  Department
TITLE or I'ROJSCT
              Development of DXA Flejiai r for Monitoring Hunan Health
IHE liCSSPACi 1CA2S1^ACT YC~:fi FiiCPOStD HE5EAKCH. OUTLINE ta.'£CTIVCS AND'.:£THODb. U\E.hFStX;ri£ ~>l-i K EY I'.DT-OS
INOT TO EXCEED H-l IN YOfP. AESTHACT.
        Tlie  nation's response to the needs for energy self-sufficiency could  increase the
   number of hazardous  .-gents thai are released into rap.'s  daily  environment.   Efficient
   and eccnonical  syste-s are needed to predict hu-.an susceptibility to hazardous agents
   and to reonitor  !'.ui.-.an populations for adverse genetic  effects v'aich rr.ay  b»  caused by
   unforsecn nuta^cns.   There is a high probability that these needs could be t-et by
   further development  of DXA-repair synthesis.  The utility of the present in  virro  CXA
   ren?-T ?• £**^!'-r-*:* ••  ^crtc '•"-" be cr.r.ir.ccd by ijvoiwpliit,  in  vivo D;\A j'upriir byiii;hc-Liii.  to
   ifli.-i'.t.'jr'j orrjan and tissue specific! ti cs of responses to hazardous agents f.nd  by usins
   these sar.e  tissues  -±s the sources of r.etabolic activation onzj7r.es for in vitro DXA
   repair synthesis  Assays.  The significlui"ce of UNA repair synthesis will be further
   enhanced  by  examinations of DXA repair in prematurely condensed  chroroso^es  and  by
   correlations of the  extentof DXA repair wi th r.C3surcir.ents of cyto^enetic aberrations,
   with r.ut3£e_!iesi_s  of  carcalian colls, and with carcinocenesis as  ncssured by  cell
   transfoliation.
  TASK:  ERR 1.15
  AGENCY:  ERDA
  FUNDING:' $60,000 - 7b
  PROJECT OFFICER: Dr.  Dean R. Parkes
LEAVt BLANK
    .
  ». 3-70
                                          207

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                        QMS No. J58-R008J
                                                               PROJECT NO. (Da not u«e Ml space)

                                                               SSIE
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                 EPA-IAG-D6-E681-ZAQ.
  TITLE OF PROJECT

        USB of Mouse  Sneeifia-Locus Method JK> Quantify the Gene  Mutation Hazard
  GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
  PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
        V. L. Russell
        Biology Division
  NAME AND
        ID ADDRESS OF APPLICANT INSTITUTION
        Oak Ridge  National laboratory
        P.O. Sox X
        Oak Ridge,  TN  37830
  SUMMARY OF PROPOSED WORK - (I) Objectives, <2) Approach. (3) Currant Plana and/or ProKres> (200 word* or !••». Omit confidential data).
     In the Smithsonian Scirnco Informal ion Exchange, summaries of work in progress are exchanged with government and private agencies tup-
   irlinff rrsearch and are forwarded to investigators who request such information. Your aummary la to be uaed for theae purpoaea.
    There are  two important aspects  to  quantification of mutagenesis in mammalian systems
    that score transmitted mutations.   First, for compounds  that are clearly  mutagenic it
    is important to be able to evaluate what the mutation  frequency would be  at exposure
    levels  likely to be experienced  by  the human population.   Some chemicals  have already
    shown a dose-response curve much steeper than linear,  and the possibility of a thresh-
    old dose level exists.  Second,  for chemicals that  show  no mutagenicity in the sample
    of animals examined in a mammalian  test system, it  is  important to have the sample
    size adequate to justify a quantified statement that the  observed zero mutation rate
    excludes,  with high confidence,  the possibility that any mutagenicity of  the compound
    could be higher than a certain  low, acceptable  level.

    The specific-locus method in mice,  the only reliable and definitive test  for trans-
    mitted  gene mutations currently  available in mammals,  will  be used.   Priority for
    these quantitative (e.g. dose-effect relationship)  tests  will be given to those com-
    pounds  which meet at least some  of  the following  criteria, namely,  chemicals which
    are:-   (a) mutagenic in our screening test with the  specific-locus method, (b) muta-
    genic in our screening test for  mouse somatic mutations  in vivo, (c)  mutagenic in any
    mammalian  test system for transmitted chromosomal aberrations, (d) mutagenic in any
    other mammalian test system, (e) mutagenic in nonmammalian test systems,  (f) chemi-
    cally related to known mutagens.

    Extensive  testing with sulfur dioxide has given no  evidence of mutagenicity.
    Benzo[a]pyrene, a compound that  might be a hazard as a result of coal conversion
    processes, and which gave some  mutagenic effect in  screening tests, is now being
    thoroughly investigated.
  IDENTIFY PROFESSIONAL SCHOOL INVOLVED (,M,;lif.il.
                N/A
                                          SIGNATURE OF PBmciPAL INVESTIGATOR
                                            W. L. Russell
                                        FOR OFFICE USE ONLY
     SUPPORT METHOD lOl.M-l. ollf)
                                                 PBpJECT_pFFICER   _
                                                 Dr.  Dean  R.  Parker
                                                 RESPONSIBLE ORGANIZATION

                                                 ERDA
Funds Estimate* F-r-
 I $175,000     76
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                                                          STARTING DATE
                                                      .      .
                                                      IATE
                                                       July 1976
       approximate not for citation.56 AND si-s.e ?BA WHICH MAY NOT BE
                                              208

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                         Form Approved

                                                                       OMB No. 758-R008J
                                        PROJECT NO. (Do not »•• Ml epace)

                                        SSIE
                                                                 EPA-IA6-D6-E681-BAQ
            CROSS-PLACENTA.. TRANSFER
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
            P.  L. Hackett. Ph.D., Biology Department
            M.  R. S1kov,  Ph.D., Biology Departaent
            D.  0. Kahlua, Ph.D.. Biology  Departaent
NAME AND ADDRESS OF APPLICANT INSTITUTION
            Battelle, Pacific Northwest Laboratories
            Biology Department
                      Uft
SUMMARY OF PROPOSED WORK - (1) Objective!, (2) Approach, (3) Current Puuu and/or Progress (200 word, or lees. Omit confidential d.t.).
   In the Smithsonian Science Information Exchange, luminaries of work in progress an exchanged with government and private ageacle* sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for fhese purposes.

 This project Is concerned trtth  heavy metals for which there 1s direct or  Inferential
 evidence for deleterious effects on prenatal development.  It will define the specific
 Influences of factors which affect the qualitative  and  quantitative aspects of the
 cross-placenta! transfer of certain heavy netals associated with energy production
 and their distribution  throughout  the  fetoplacental unit as a function of tine after
 exposure to define the  tissues  at  risk and provide  quantitative estimates of  dose.
 In Initial studies Involving lead, transfer and distribution are being evaluated at
 four different gestatlonal ages selected to represent stages 1n the continuum of
 embryonic and placenta!  development.  Intravenous,  oral, and Inhalation routes of
 administration, which will provide differences 1n the rate at which the metals are
 presented to the placenta as well  as possible differences 1n their chemical binding
 In blood, are being  compared.   Since metabolism may be  Influenced by the  mass administered,
 a low dose as well as one 1n the teratogenlc range  1s being studied.  This will
 provide a reference  point.,for comparison with available data on teratogenesls as well
 as a basis for design of studies to establish dose-response relationships.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED r,V
dm/ill, rfc.)
          NA
                                         SIGNATURE OF
                                                                              10/6/76
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD (C.irrk ain<)
                         PROJECT OFFICER

                             N.II  UJ-
                                                RESPONSIBLE ORGANIZATION
 FUNDS OBLIGATED

  /00.000
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                                       (,-1-73-
S-21-79
     o,m 5740-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                               209

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                  U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
         PREPARED tOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                             Form Approved
                                                                           OMB No. 1SS-R0081
                                                                  PROJECT NO. (Do not u«e thlt space;
                                                                  SSIE
                                                                      EPA-IAG-D6-E-681-BAQ
    TITLE OF PROJECT  Teratogenlc  and Mutagenlc  Effects ot Trace detais  and Carcinogenic
                   Hydrocarbons on Cultured Mammalian Cells
    GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
    PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
    Principal  Investigator:  Jean de Vellis,  Ph.D., Associate Professor of Anatomy
                               (213) 825-8734   (See address  below)
    Co-Investigators:        L.  Gerschenson,  M.D.; H. Herschman, Ph.D.; and I. Harary, Ph.D.
    Personnel:                K.  McCarthy, Ph.D., Postdoctoral Research Fellow, Toxicologist
    NAME AND ADDRESS OF APPLICANT INSTITUTION
                       Laboratory of Nuclear Medicine and Radiation Biology, UCLA
                       900 Veteran Avenue
    	Los Angeles, California 90024	
    SUMMARY OF PROPOSED WORK - (1) Objectives. <2) Approach, (3) Current Plan* and/or Progress (200 words or Isss.  Omit confidential data).
      In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
    porting research and are forwarded to investigators who request such Information. Your summary is to be used for these purposes.

       The aim of this project is to validate the use of cell cultures  from nervous
    tissue, liver and muscle  on fast, easy,  quantitative and reliable test systems  to
    evaluate  the potential teratogenic and mutagenic effects of trace heavy metals  and
    carcinogenic hydrocarbons released during the combustion of fossil  fuels.  We are
    specifically studying:

       a)   The effect of  lead and cadmium on general growth parameters  of several cell
            types.

       b)   The effect of  lead and cadmium on the developmental expression of
            differentiated functions in liver, brain and muscle cell  cultures.

       c)   The induction  of cadmium binding  protein or  metalothionin in cultured  liver
            cells.

       d)   The establishment  of lead resistant cell lines and the mechanism for this
            resistance.
    IDENTIFY PROFESSIONAL SCHOOL INVOLVED Medical,
    dental, etc.)
                 Medical School
                                            SIGNATURE OF PRINCIPAL INVESTIGATOR
      SUPPORT METHOD (Check one)
       RESEARCH GRANT
 Funds Estimate*
   ($100,000
76
                                          FOR OFFICE USE ONLY
                                                   PROJECT OFFICER
                                                   Dr. Dean  R.  Parker
      NO. OF FUTURE YEARS TENTATIVELY
      ASSURED BEYOND CURRENT F.Y.
                                RESPONSIBLE ORGANIZATION

                                IRPA-
                                         STARTING DATE
*Funds approximate not for citation.66 AND S|-STE 76A *HICH MAY NOT BE USED.
July  1976
                                               210

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              O.S, ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                       Form Approved
                                                                      OHB No. 1SS-KOOS1
                                              PROJECT MO. (Da not use thi, «n,cej
                                              SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                              IPA	
                                               EPA-IAG->O6-E681-BAU
of Fuel on
                                                                                 Consumptio:
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
John L. Skosey, M.D., Ph.D.
Associate  Professor of Medicine  and
The Franklin McLean Memorial  Research Institute
The University of Chicago, Box 420
                                     950 E.  59th Street
                                     Chicago,  Illinois  60637
                                      (312) 947-5062
NAME AND ADDRESS OF APPLICANT INSTITUTION
The  University of Chicago
Office of Sponsored Programs
                         5801 So. Ellis
                         Chicago, Illinois   60637
SUMMARY OF PROPOSED WORK - (1) Objective*. (2) Approach. (3) Current plan! and/or Progress (200 urordm or l>aa. Omit confidant!.1 data).
   In the Smithaonian Science Information Exchange, summarie» of work in progress are exchanged witH government and private agenclea »up-

  There  is a three fold  rationale for studying the effects  of  chemical  toxicants on the
function of phagocytic cells.  Firstly, chemical toxicants may  interfere with the functio:
of phagocytic cells in defenses  against external agents such as bacteria and viruses.
Secondly, pathological effects of certain toxicants such as silica and  asbestos particle:
may be mediated through  their  effects on phagocytic cells.  Thirdly,  phagocytic cells
mediate  the pathological consequences which result from agents responsible for, e.g.,
rheumatic diseases; chemical toxicants may alter responses  of  phagocytic cells to these
agents and to their adverse  effects.
  Studies designed to elucidate  the mechanism by which phagocytic cells may mediate the
pathological effects of  particles (e.g. silica, asbestos, quartz, carbon) are in progres:
We have  shown previously that  neutrophils respond to monosodium urate crystals coated
with  imraunoglobulin by releasing lysosomal enzymes. This secretion of enzymes occurs wit
out significant cell death.  Studies are in progress to determine if other particles whic!
initiate inflammatory tissue damage similarly interact with immunoglobulin and to deter-
mine  the effects of such immunoglobulin coated particles upon  neutrophils. In parallel,
studies  are in progress  to determine the effects of pollutant  gasses upon physiological
and pathophysiological responses of neutrophils and to determine the mechanisms of these
effects. Initial studies have  demonstrated that the responses  of neutrophils are depend-
ent upon the oxygen tension  of the medium used for incubation. Reduction in oxygen ten-
sion  results in increased release of lysosomal enzymes in response to phagocytable parti
cles,  an increased rate  of anaerobic glycolysis  (reflected  in  increased lactate product!
and a decreased rate of  glucose  oxidation. Studies are in progress to determine the
mechanism of these effects of  altered oxygen tension.
                                                                             n)
IDENTIFY PROFESSIONAL SCHOOL INVOL.VFO O/cJ/c.;/.
i/,.r,,.,j, <.,c.) The University of Chicago, Div.
of Biological Sciences S Pntzker School
          of Medicine
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                           DATE

                                                            10-28-76
                                      FOff OFFICE USE ONLY
   SUPPORT METHOD fCheck t
    NEGOTIATED CONTRACT
                               PROJECT OFFICER
                                M. L; Mint horn
                               RESPONSIBLE ORGANIZATION
                               ERDA
FUNDS OBLIGATED
$50, 000
Carry-Over
75
      FNO OF FUTURE YEARS TENTATIVELY
       ASSURED eEYOND CURRENT F.Y.
STARTING DATE
5/1/75
ESTIMATED COMPLETION
DATE
7/1/80
                                               211

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form. Approved
                                                                        OMB No.  U8-R0081
                                                               PROJECT NO. (Do not uea this epacej

                                                               SSIE
                                                               EPA	

                                                                EPA-IAG-D6-E681-BAU
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PROJECT     	
  Effects of  Environmental Pollutants op the  Development  of the Immune Response	
OIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

  Bernard N.  Jaroslow, Immunologist, Division of Biological & Medical Research
  Katherine M.  Suhrbier, Scientific  Assistant, Division of  Biological & Medical  Research
  Suzanne S.  Dornfeld, Scientific Assistant,  Division of  Biological & Medical Research
NAME AND ADDRESS OF APPLICANT INSTITUTION
  Argonne National Laboratory
  9700 South  Cass Avenue
  Argonne.  Illinois  60439	
SUMMARY OF PROPOSED WORK - (1) Objective!, (2) Approach. (3) Currant Plans and/or Progress (200 word, or less. Omit confidential data).
  In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigator! who request such information. Your summary is to be uaad for these purpose*.

       We are  studying the  short- and long-term effects  of important  carcinogenic,
  environmental pollutants  on the immune  response of mice.  The test  carcinogens  will
  be given as  single injections at 3 doses  in relation  to their carclnogenicity—the
  100%, the 50%, and the  10%  carcinogenic doses-.-  In addition, we will assess the
  effects of the agent when it is given daily at levels  equivalent to those  of an
  individual at risk.in. the industrial  environment.  Mice will be treated at different
  ages and their immune response will be  assayed from a few days to two years after
  exposure to  the carcinogen.  Immunologic competence will be assessed by measures of
  antibody-forming capacity and by measures of cell-mediated immunity, both  in vivo
  and in  vitro.  A comparison of the effects of large doses of methylcholanthrene
  (250-1000 ug/mouse) on  production of  antibody-forming cells and on  production of
  specifically cytotoxic  cells shows that the antibody  response is more sensitive
  to drug inhibition than the cell-mediated response.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.
dental, ere.)
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                         Bernard N.  Jaroslow. Ph.D.
                                                                       DATE

                                                                       October 27, 1976
                                      FOB OFFICE USE ONLY
   SUPPORT METHOD (Check one)
    AGENCY STAFF flntrl
                       TASK NO.


                             6
                                               PROJECT OFFICER
                                                Warren R. Sinclair
                                               RESPONSIBLE ORGANIZATION

                                                 ERDA
FUNDS OBLIGATED
        1 £ rwi
        'ver)
               75
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED SEYONO CURRENT F.Y.
                                                        STARTING DATE
                                                             1/76
                                                                         7/78
EPA FormS760-l (7-72)    REPLACES PH5 FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                           212

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*"- — "•— - " '— -
Pftfpcred fcr the
Han Exchcn^r.
Not (or pgbii.--ot
reference.
Sc
or publication
                                       U. S. Pcporinvint of
                               HEALTH. EDUCATION, AND V/P.LFARE
                                      PUOtlC HKALTH SERVICE

                               NOTICE OF  RESEARCH PROJECT
                                                                    PROJECT NO. (DO NOT US1 THlT"
                                                                    EPA-IAG-D6-E772-BCO
TITLE OF PROJECT                          ~      ~~	

 Computer Iji V i vo  Detection of Mutations  in Somatic and Germinal  Cells
S'RVoEFKS^                                 INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER

 PROJECi  OFFICER:  H.  V.  Mailing, Head,  Biochemical Genetics  Section, Environmental
                    Mutagenesis Branch
 NAME AND ADDRESS OF APPLICANT INSTITUTION
 NIEHS,  P. 0. Box  S2233, Research Triangle Park, North Carolina   27709
 SUMMARY OF PROPOSED WORK -(200 »o,ds or l«t-0mif Confident;.,) Join.)

 tho bio-sciences and ore forwarded to investigators who request such information. Your summo:y U to be used for these purports,

  (a)   Somatic mutations  in vivo

  The  purpose of  this  investigation  is  to develop methods  by  which the frequency of  somatic
  point mutations  at several genetic  loci  in experimental  animals  and human brings can  be
  [Treasured.  Sccauss blood is 2  readily available source cf somatic cell: thst hsva  2 high
  turnover rate,  we  will  initially  attempt our studies with the  use of blood.  Methods  b^scd
  on differential  staining of mutated and non-mutated calls will  be developed.  Antibodies
  flagged with fluorescent moieties will  be produced to  identify  cells containing aberrant
  mutant' proteins.

  This system will utilize automatic  detection of variant  cells  by a cytograph and the  data
  will be stored  and analyzed with  the  computer.

  (b)   Point mutations in male germinal  tissue

  The  purpose of  this  investigation  is  to develop methods  by  which point mutations can  be
  detected directly  OP. spermatogonia, spermatic] and sperm.  The  nutant cells will be detected
  by differential  histo'chemical  stains.   Several enzyme  systems  wifl be employed, seme  conw.on
  for  somatic cells  and the germinal  tissue, some specific fcr the sperm.

  Detection of aberrant sperm cells will  involve the use of an automatic scanning n,icroscope
  which will be. hooked into the  computer.

  Task: ERR 1.3
 PROMEitlO: AL JCKOO-- Iwjical, rfcfto/', rrcj WITH
 WHICH THIS PROJKCT JHCULP BE IDENTIFIED
                                           SIGNATURE OF PRINCIPAL lUVESTIOATOtl

                                             //•I'- A/ii//i.i.-	
                            DO NOT WhlTF aELQ''< TH'S LIN'; - FQH OFrlCr U5.U Cy'
 SUPPORTING AC.ENCr
^
 METHOD OF SUPPORT fO
 n /.,,=„„ S,=,i
                                     n  tp"io1 -
                                     '—I  P-o.c = l6,oV
T:.,'77rr;r—F7T~frrn7^TJVF'F   i hUMBEf! OK FUTURE "r.m; TanATIVCLV ;.<;uR!io  st6iKN..iG C*TL    f.s.i'y-./rn	
 r-..M'« 1/l^lCAir.i) CjSr-.t., , I.'-   rB^Yo;j0 CURRtSl  FISC-xL Y£AR                              I  C.OMPL:. , ifJl! C.. • c
     0                76

 HI'l-191', (f '.C.'.T. ftLY PH5-166)
                                                                                     1977
                                             213

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               U.S. ENVIRONMLNTAl. PhOTCCTlON AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        r>vn .\V
                                                               PROJECT NO. (tOd nut us*- thin *|.»civ
                                                               __	

                                                                EPA-IAG-D6-E772-BCO
     PREPARED TOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PROJECT
Development of a System for Detecting Lethal Mutations  in Mice
owe NAVES. CJEPAHTMCNTS. AND OFFICIAL TITLES or PRINCIPAL INVESTIGATORS on PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Contractor', s Project Director:  Thomas H. Roderick,  Ph.D.,  The Jackson Laboratory, Bar
Harbor,  Maine
Project Officer'(NIEHS):  William Sheridan, Ph.D., Mammalian Genetics & Cytogenetics
Section,  Environmental Mutagenesis Branch'
NAME ANO ADDRESS OF APPLICANT INSTITUTION
National Institute of Environmental Health Sciences,  P.O. Box 12233,  Res. Tri. Park, N.C.
27709
SUMMARY OF PROPOSED »OPK - ll) Objeclii-fs. (2) Approach. (J) Currcr.i Pljtn and/or Ptoina, C200 worjs of :ess. Omit confider-.iia! .
   In the Smithsonian Science [information Eirharitte. summaries of work in prepress arc exchanged *-i:h government and private agencies »-jp-
pvrtinc relearch Bod are forwarded to investigators who request such information. Your summary is to be used for these purpose*.
    The contractor induces chromosome breaks and inversions by means of radiation and/or
 chemical agents.  He mates the treated animals and in the F"i does cytological analysis
 of one  testis of each individual male.  If a significant increase in anaphase bridges appears
 this is taken as an indication that the animal may carry an inversion;  and he is mated to
 get offspring for further study.  Following  cytological and linkage studies  to characterize
 the aberation,  decision is made as to the utility of the inversion and  appropriate marker
 genes are introduced into the stock.

    The contractor has induced and recovered 31 inversions.  Of these,  14  have been thoroug
 characterized for  linkage and chromosomal morphology.  One of the  inversions has  been
 successfully utilized in  tests to detect induced recessive lethal mutations.
 JfNVIFY P^Of-ES5IONAL SCHOOL INVOLVED (M*Jte*t.
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                      FOR OFFICE USE_pSLY_
                                               PROJECT OTFICtR
    •rcr Alien GRANT
' U'.CS OOLIGAT^^T TF.V!

$50,000       76
                                                Dr. Fred de Serres
                                               RESPONSIBLE ORGANIZATION

                                                NIEHS
*O. O*' TuTu^C VEAWS TE'IT ATivELY
Assuht-o otiONo CUHHENT F.Y.
                                                        STARTING DATE
                                                                            f.STIMATfO
                                                                            DATE1977
EPA form 5740-1 <7-72)    REPLACES PMS FORM I6S ANO SI-SIE 76A WHICH MAY NOT BE USED.
                                            214

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              U.S. ENVIRONMENT At, PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
[ITLL OF PROJECT
                                                                          \a.
               PROJECT NO. (139 rmt u«f thin

               SSIE
                                                              EPA-IAG-D6-E77 2-BCO
 Development of a New Mouse Strain to Maximize Sensitivity of a Point Mutation Assay
 IVE NAMES. OEPARTMtHTS. AND OFFICIAL TITLES OT PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED [M THE PROJECT.
 Contractor1 s Project Director:  Thomas H.  Roderick,  Ph. D.,  The Jackson-Laboratory
 Project Officer (NIEHS):  Lawrence R. Valcovic, Ph.  D., Staff Fellow,  Biochemical
 Genetics Section,  Environmental Mutagenesis Branch
NAME AND ADDRESS OF APPLICANT INSTITUTION
  National Institute of Environmental Health Sciences, P.O. Box 12233,  Res. Tri.  Park,  N.C.
  27709
SUMMARY OF TROPOScO V.ORK -  U) Ob«-
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                      FOR OFFICE USE OSLY
   SUPPORT MLTMOD rOu-rfr omv
     T ST AI1CH GRAN T
                             TASK NO.

                                 1.5
PROJECT OFFICER
Dr. Fred de Serres
RESPONSIBLE ORGANIZATION

 NIEHS          	
 •OliCS OOLIGAYf.O Tr^T.   |KO. OF FOTOUC YEAOf TC'ITATIVCLV
                      ASSUhLD BETGNO CURRENT F.Y.
  $39,433        76  )
                                                        STARTING DATE
                            F.STIMATEO
                            DATE
                            1977
 CCA r«,mS740-l (7-72)    RCPLACES PMS FOflM 166 ANO 51-SIE 76A WHICH HAY NOT BE USED.
                                           215

-------
Proportd for lh« Sc
Kon Exchange.
Not for publication
reference*
erico Informo-
or publication
                                      U. S. Deportment of
                              HEALTH, EDUCATION, AND WELFARE
                                     PUBLIC HEALTH SERVICE

                              NOTICE OF  RESEARCH PROJECT
                                                                   PROJECT NO. (BO NOT USE I HIS SPACE)
EPA-IAG-D6-E772-BCO
TITLE Of-' PROJECT
 Amplification of  Point Mutation System:   Characterization  of Mouse Esterases  by
 Isoelectric Focusing

GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR  PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED ON THE PROJECT.
 CONTRACTOR'S PROJECT DIRECTOR:  Or. Robert Allen, Medical  University of South Carolina,
                                  Charleston, South Carolina

 PROJECT OFFICER (NIEHS):  Dr. L. R. Valcovic,  Acting Assistant Chief, Environmental
                            Mutagenesis  Branch
NAME AND ADDRESS OF APPLICANT INSTITUTION
 NIEHS, P. 0. Box 12233, Research Triangle Park, North  Carolina  27709

SUMMARY OF PROPOSED WORK -(200 wWj or les« -Omir ConfrVentio/ date.)
  In the Science Information Exchange summaries of work in progress are exchanged with government and private agencies supporting research in
the blo*iciencos and are forwarded to investigators who request such informotion. Your summary is to be used for these purposes.

 The research seeks to characterize esterases of C57BL/6J and DBA/2J mice with  gel iso-
 electric focusing.  Esterases from plasma, red blood cells  and kidney of both  strains as
 well as  the  Fj  interstrain hybrid shall  be subjected to  two-dimensional analysis.
 Discontinuous gel  zymograms of these  enzymes have been described previously  and hence this
 technique wi11  be  used for the first  dimension separation.   Subsequently,  isoelectric focus
 will then be conducted using  thin slab aeryiamide gels.  Various pH ranges will be employee
 in order to  determine the isoelectric point of each esterase band.

 Since the projected use of this technique involves screening large number of mice, this
 contract should entail a sufficiently large sample  to  place a reliable confident  interval
 for the  isoelectric point of  each esterase band.
  Task:  ERR  1.7
PROFESSIONAL SCHOOL (merited, dcniol, elcj WITH
WHICH THIS PROJECT SHOULD BE IDENTIFIED
                           DO NOT WRITE BELOW THIS LINE - FOK OFFICE USE ONLY
SUPPORTING Afg
           SftfiftS/Project Officer:  Dr. Fred  de Serres
METHOD OF SUPPORT
D Agency Staff
(Intramural)
FUNDS OBLIGATED C
0
(Check onej
D Negotiated
Cuntroet
JRREHT F.Y.
76
D Special
Project G
rant
a
NUMBER OF FUTURE YEARS TENTATIVELY
BEYOND CURRENT FISCAL YEAH
Research fl
Great 1 — 1
ASi'JRFO
Other
(Spcclly)
BEGINNING DATE
ESTi,iAT;n
COMPLETION
1977

DATE
                                              216

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               U.S. ENVIRO'IMLIITAL PhOI ECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        Farm Affr
                                                                       OMft \<>.  M5
               PROJECT NO. (Do

               SSIE
     PREPARED TOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                              EPA-IAG-D6-E77 2-BCO
 Development of a Polygenic Assay for Induced Point Mutations in Mice
GIVE NAMES. DEPAHTMLNTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT CIRECTOHS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 'Contractor1, s Project Officer: John W. Crenshaw,  Jr., Ph.D., Georgia  Institute of
 Technology
 Project Officer -(NIEHS):  Eugene R. Scares, Ph.D., Staff-Fellow, Mammalian Genetics
 and Cytogenetics Section,  Environmental Mutagenesis Branch
MAME AND ADDRESS OF APPLICANT INSTITUTION

  National Institute of Environmental Health Sciences, P.O.Box 12233,  Res.Tri.  Park.N.C.
  27709
SUMMARY Of PROPOSED V.OP.K -  ,1) Ob-.-cllv,.-.. (2) Approach. <)) Current PLins ,,r.rt/or Pros;m 1200 »orjs or :ess. O=>it cor.ddcr.ii.,: Jala).
purling research «nd are forwarded to investigators who req,-jesl such information. Your summary is to be used lor these purposes.

  The scope of this contract is to develop an understanding of the  mutagenic effects in mice
  of some known mutagens, as measured by mean and variance changes in polygenic
  characters.

  The contractor proposes to investigate the cumulative effects  of  multiple mutagen-induced
  polygenic mutations on a series  of traits  on Fj and F2 generation progenies descended
  from mutagenized males of an inbred strain of mice.  Fj and 72 progeny will  be examined
  for a series of traits including:  age of eruption of incisors, mean and variance of body
  weight at weaning,  sex ratio at weaning,  serum cholesterol level at weaning,  and hemato-
  crit at weaning.  The contractor proposes to study at least two different  mutagens in
  two strains of mice.

  The first  semiannual report indicated that data collection was proceeding as  scheduled &
  statistical analysis of the collected data  will begin  shortly.
1-JffiriFY PF,Ofr ESSIONAL SCHOOL INVOLVED r.V.
If.-rir../. r!i!.t
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                      FOR OFFICE USE ONLY
   SUPFORT MCTHOD .C/i.-cfc t-rtt-.'
                            TASK NO.

                                  ERR 1.8
PROJECT OTFICtR
 Dr  Fred de Serres
                                               RESPONSIBLE ORGANIZATION

                                                NIEHS
'U'iC- OOLIGA rf.O  IF.Y.   | «jQ. OF

  $70,000
                                  E»B«, TC'lTATIVCLr
 F Y    NO. o»'ruTor=Cv£'vR?TCllTaTi'
       ASSUHt-D OOGNO CUHRENT F.Y.
r5    I	
                                                        STARTING DATE
                            r.STIMATtD C
                            DATE 1977
EPA Fo»m 5760-1 (7.72)    RCPLACFS PMS FOHM '6G ANO 51-SlE 7&A WHICH MAY NOT BC UStD.
                                             217

-------
Pr*pof«d fof th» Sc
lion Exchange.
Not for publication
raf«r*nco«
enco Informo*
or publication
                                          U. S. Deportment of
                                 HEALTH, EDUCATION, AND WELFARE
                                        PUBLIC HEALTH SERVICE

                                 NOTICE OF RESEARCH PROJECT
                                                                       PROJECT HO. (00 NOT USE THIS SPACE)
EPA-IAG-D6-E772-BCO
  TITLE OF PROJECT
   Detection  of Point Mutations in Somatic Cells
 ' GIVE NAMES  DEPARTMENTS AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AMD ALL OTHER
  PROFESSIONAL PERSONNEL ENCAGED ON THE PROJECT.
   CONTRACTOR'S PROJECT  DIRECTOR:   Dr.  Peter E.  Mute, University of Washington,  Seattle
                                      Washington

   PROJECT  OFFICER (NIEHS):   Dr. H.  V.  Mailing,  Geneticist,  Biochemical  Genetics  Section,
                               Environmental Mutagenesis Branch
  NAME AND ADDRESS OF APPLICANT INSTITUTION
   NIEHS,  P.  0.  Box  12233,  Research  Traingle Park,  North Carolina  27709
 ~ SUMMARY OF PROPOSED WORK -(200 worrfs or leu -Omit Conf.demioJ data.)
    In the Science Informotion  Exchonge surrtmories of work in progress cte exchanged with government ond private agencies supporting research in
  the bio-sciences and ere forwarded to investigators who request such information. Your summary is to be used for these purpose*.
   The purpose of this  investigation  is to develop a simple system to  measure point mutations
   in readily accessible  human somatic cells.   Antibodies  to  each of  two types of  fetal
   hemoglobin will  be  produced and used to search  for  individual mutant cells within a
   population of cells.   Some monospecific antibodies  to variant human hemoglobins have been
   acquired and purified.   These antibodies will  be used  in developing tests for detecting
   a human  mutation  rate.
Task:   ERR 1.9
  PROFESSIONAL SCHOOL (medical, dental, etc.I WITH
  WHICH THIS PROJECT SHOULD BE IDENTIFIED
                                             SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                                         DATE
                              DO NOT WRITE BELOW THIS LINE - FOR OFFICE I
                                                                    ONLY
  SUPPORTING AGENCY
    NIEHS/Proiect  Officer!
                                        Frorf
METHOD OF SUPPORT (C/.ccJc one)
D    Agency Staff      I   I Negotiated
    (Intramural)       I	1 Contract
D Special
Project Grant
D                                                               Research
                                                               Grunt
    1  I Other
    1 - 1 (Specify)
FUNDS OELICATER •.
$85,000
URRENT F.Y.
76
HUHBER OF FUTURE YEARS TENTATIVELY ASSURED
BEYOND CURRENT FISCAL YEAR
BEGINNING DATE
ESTIMATED
COMPLETION DATE
1977
                                             218

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  Prepared 'or thfi Science Informe*
  tion Exchange.

  Nof (or publication or publication
  reference.
         U. S. Duportment of
HEALTH, EDUCATION, AMD WELFARE
        PUBLIC HEALTH SERVICE

NOTICE OF RESEARCH PROJECT
                                                                     PROJECT MO. 0 HOT USE THIS SPACE)
EPA-IAG-D6-E772-BCO
TITLE OF PROJECT                 ~	'	
Development  of Faster,  More Efficient and Less  Costly Methods for  Determining Teratogenic
Changes
                ^^^^                               INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
Contractors^ Project  Director:   Dr.  Franklin M.  Johnson,  Research  Triangle  Institute

Project Officer  (NIEHS):   R. E.  Staples, Ph.D., Research Physiologist,  Environmental
                             Toxicology Branch
NAME.AND ADDRESS,OF APPLICANT INSTITUTION  ...  ,.,,..
National  Institute  of Environmental Health  Sciences
P.O. Box  12233, Research Triangle  Park, North Carolina   27709
SUMMARY OF PROPOSED WORK -(200 wort's or I,,,-Omit CW«fen'ia< dots.)
   In tho Science Information Exchange  summaries of work in progress ore exchanged with government and privote agencies supporting reseorch in
the blo*sciences and are forwarded to investigators who request such information. Your summary is to be used for these purposes.

Mouse  and rabbit  embryos will  be exposed  to gaseous coal by products  such as  SO^ and MV
during culture in the preimplantation period, and, to sulfur-and nitrogen-containing com-
pounds by intrauterine injection during the postimplantation period  of gestation.  Sub-
sequent effects on  the developmental process will be compared  to those noted  after exposure
to the same test  agents by  inhalation.
Task:   ERR-  1.11
PROFESSIONAL SCHOOL fmedicol, denro/, elc.J WITH
WHICH THIS PROJECT SHOULD BE IDENTIFIED
SIGNATURE OF PRINCIPAL INVESTIGATOR
DATE
DO NOT WRITE BELOW THIS LINE - FOR OFFICE USE ONLY
suppotTO£7¥roject Officer: Dr. Fred de Serres
 METHOD OF SUPPORT fCh.ck
    DAg.nc, Stall       [~~] Nojoll.le.
    (Intramural)       '	' Conlioct
          DSp.ciol            1  I  Reseorch       I  I  Other
          Projec! Grunt        I	1  Oror,t         I	l(Sr)ecilr)
FUNDS ORLIC.,
$50,000
.TED CURRENT F.Y.
76
NUMF.CR OP FUTURE
EEl'OND CURRENT f
YEARS TiiHTATIVELY ASSURED
5CAL YEAR
BEGINNING DATE
ESTIMATED
COM!"LtT!ON OATE
1977
        (FORMERLY PH3- I6«>
                                            219

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                 	SSCT'OM 1	

                  DEPARTMENT OF HEALTH. EDUCATION. AND WELFARE
                            PUBLIC HEALTH SERVICE

                         RESEARCH OBJECTIVES
        LEAVE DLANK
PROJECT NUMUF.n
                                                                 EPA-IAG-D6-E772-BCO
 NAME AND ADDRESS OF APPLICANT ORGANIZATION
 college of Physicians s Surgeons cf Colizrfcia University, Department of'Pediatrics
 630 West 168th Street, New York, N. Y. 10032	
 NAME. SOCIAL SECURITY NUMBER. OFFICIAL TITLE, AND DEPARTMENT OF ALL PROFESSIONAL PERSONNEL ENCAGED ON
 PROJECT, BEGINNING WITH PRINCIPAL INVESTIGATOR
 Arthur D. Eicon, 033-24-3679, Professor,  Departments of Pediatrics  and of Human Genetics
      and Development
 Herbert S.' Rosenkranz, 096-28-7438, Professor, Department of Microbiology
 William T. Speck, 149-30-2147, Instructor, Dept. of Pediatrics; Attending Physician, Babies
 Sherie  L. Harrison, 554-60-7614, Assistant Professor, Dept. of Microbiology        Hospital
  Barbara Travis, 118-28-1883, Research Associate,  Dept. of Kurran Genetics & Development
 Eezalel Gutter, 106-54-0400, Research Associate, Dept. of Microbiology


 TITLE OF PROJECT
 Mutagersesis in Cultured LyTrphocytes	
 USE THIS SPACE TO ABSTRACT YO'JR PROPOSED RESEARCH. Ol/TLINE OBJECTIVES AND METHODS. UNDERSCORE THE KEY WORDS
 (NOT TO EXCEED 10) IN YOUR ABSTRACT.

      Ihis project involves the development of UBirmalian  lyrghoid culture  systems to test
 for the rajtagenicity of environmental agents.   Gonpcunds Miich are known  mutagens (such
 as alkylatLng agents, and franeshift mutagsns)  will be tested in human and lyrohoid cell
 lilies for the induction of nutations at the hypoxanthine-guanine phosphoribcsyl trans-
 ferase and the argininosuccinic acid synthetase loci,  and  in  marine  lynphcid cells  for the
 induction of altered imuunoglcbulin.   The induction of chrcnosoral breakage in  these cell
 lines will ba studied using the G and H banding techniques.In addition,  the research
 vriill utilize bacterial test systems to detemine the relationship between mutageniciti' in
 siirpler organisms and in nore cotplex, differentiated manmalian cells.
Task:  ERR -  1.13
 LEAVE BLANK
Agency: NIEHS
Funding:  $199,000  - 76
Project Officer:    Dr. Fred de  Serres
Est.  Completion Date:   1977
   *IH 338 [FCSHERLT PH! 353)                     PAGE J
   »•«. 'm
                                      220

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                 DEPARTMENT OF HEALTH, EDUCATION. AND WELFARE
                           PUBLIC HEALTH itnviCE                   PROJECT NUMBER	
                                                                 PA-LAG-D6-E772-BCO
                                                                       LEAVE OLANK
                         RESEARCH OBJECTIVES
NAME AND ADDRESS OF APPLICANT ORGANIZATION	~~—~
Thfi University of Texas System Cancer Center, M.  D.  Anderson Hospital & Tumor Institute
Houston, Texas  77025
NAME. SOCIAL SECURITY NUk'SSR. OFFICIAL TITLE. AND DEPARTMENT OF ALL PROFESSIONAL PERSONNEL tNOAQEO OH	
PROJiCT. BEGINNING WITH PRINCIPAL INVESTIGATOR                                ~""". •-r,u«ueu v«

   Michael J. Siciliano, Department of Biology, M. D. Anderson Hospital & Tunor Institute.
       Principal Investigator, Assistant Professor arid Assistant Biologist. 067-30-5509.

   Ronald M. Humphrey, Department of  Physics, M.  D.  Anderson Hospital & Tumor Institute,
       Co-Investigator,  Chief Section of Cellular Studies, Dept. of Physics. 460-44-5590

   T. C. Hsu, Department of Biology,  M. D. Anderson Hospital & Tumor Institute,  Co-
	Investigator, Chief Section of Cell Biology.    467-60-6146
TITLE OF PROJECT                    ——   ——________________________—
     MULTIPLE LOCI SC-tlEN' FOR MJTATIOSS IN MMKALIAH  CELLS
16* THIS SPACE TO ABSTRACT YOU3 PROPOSED RESEARCH. OUTLINE OBJECTIVES AND METHODS.  UNDERSCORE THE KEYWORDS
WOT TO EXCEED 10] IN YOUR ABSTRACT.
     It is our intention to develop a new system for testing the mutagenic potential of
various envircnj.ental agents on namalian somatic cells.  The basis  of the procedure is
to expose cells to ::utsgen and plate  out single cell clones.   Clonal isolates,  after
teing grown up to 40 s 10° cells, are then screened for electrophoretic variation  of
the products  o* over 40 genetic loci.  Where a clonal variant is detected,  it is  iso-
lated and its heritability determined by subcloning and subsequent electrophoresis.
The procedure avoids =any of the problems associated with the detection on selective
systems of recessive nutations (auxotrophic,  drug resistant,  and temperature  sensative)
in diploid maamalian cells since electrcphsretic  mutations are co-dominant.   Lack  of
enrichment for mutants by selection is also compensated for by the increased  probability
of obtaining an electroohoretic shift in a protein as the result of  a single  nucleotide
substitution in its gene as opposed to the complete loss of function by such  an event
and, the study of the products of a large number  of loci.   Additional attributes of
the procedure are that:  each variant cay be associated with a specific genetic locus,
nutations in a wide range of genetic loci may be  studied,  the system requires no change
in-the medium limiting the cause of any observed  variation to intracellular events,  and
nutations in both structural genes as well as those affecting gene expression can  be
specifically detected.

     Our preliminary studies using Chinese hamster ovary cells (CHO) have revealed that
ve can electrophoretically characterize the products of 51 structural enzyme  loci  and
detect variants at both structural and control loci.  We wish to continue these studies
in order to optimize various parameters of the procedure — dosage of mutagen,  time of
cloning and stage of the cell cycle for mutagen treatment  —  and to use the system to
study mutation frequescias under a variety of conditions.

LEAVE BLANK                                          '                                  ~~

 Task:   ERR -  1.14
Agency:  NIEHS
 Funding:   $90,000  -  76
 Project Officer:   Dr.  Fred de Serres
 Est.  Completion Date:  1977
  »iHjj! (FMxiftiT PKS 3;»)                     CAGE j
                                            221

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NOT FOR
PUBLICATION
OR
PUBLICATION
REFERENCE
SECTION 1
DEPARTVENTOF HEALTH. EDUCATION. AND WELFARE
PUBLIC HEALTH SERVICE
RESEARCH 68JECTIVES
LEAVE BLANK
PROJECT NU'.'SER
EPA-IAG-D6-E772-BCO
 NAME AND ADDRESS OF APPLICANT ORGANIZATION

    Stanford Research Institute,  333 Ravenswood Avenue,  Menlo  Park,  California   94025

 NAME. SOCIAL SECURITY !»L'VSE=>. OFFICIAL TITLE. AND OEPAHTMENT OF ALL PROFESSIONAL PERSONNEL ENGAGED ON
 PROJECT. BEGINNING WITH PRINCIPAL INVESTIGATOR
    A.  D. Mitchell  (459-62-8786)  Principal  Investigator, Cell Biologist,  Bioredical Research
         Department

    K.  Stefos (452-6S-71T9) Postdoctoral  Fellow in  Cell  Biology,  Bio-edical  Research
         Department

    M.  V. McMacfcen  (383-09-4277)  Biochemist, Bioraedical  Research  Department
 TITLE OF PROJECT
               Developcent  of DN'A Repair  for Monitoring Human Health
 USE THIS SPACE TO A3STHACT YC-fi PROPOSED flESE ARCH. OUTLINE OBJECTIVES AND METHODS. UNDERSCORE THE KEYWORDS
 INOT TO EXCEED 101 IN YOLJR ABSTRACT.
         The nation's response  to the needs for energy self-sufficiency could  increase  the
    number of hazardous  agents  that  are released  into nan's daily environment.  Efficient
    and economical systems  are  needed to  predict  human susceptibility  to hazardous agents
    and to monitor hurean populations for  adverse  genetic  effects vhich say be  caused by
    unforseen nutagens.   Tnere  is a  high  probability that these needs could be cet by
    further development  of  DXA  repair synthesis.  The utility of the present in vitro DN'A
    repair synthesis tests  can  be enhanced by developing  in vivo DSA repair synthesis to
    r.e=£isre organ and tissue specificities of responses to hazardous agents and by using
    these sane tissues zs the sources of  metabolic activation enzyr.es for in vitro DXA
    repair synthesis assays.  The significance of DXA repair synthesis will be further
    enhanced by examinations of DXA  repair in prematurely condensed chromosoaes and by
    correlations of the extent of DN'A repair with  neasurenents of cytogenetic aberrations,
    with  nutagonesis of  narjnalian cells,  and with carcinogenesis as measured by cell
    transformation.
 LEAVE BLANK
Task: •  ERR-1.15
Agency:   NIEHS
Funding:  $80,000  - 76
Project Officer:   Dr. Fred  de  Serres
Est. Completion Date:  -1977
 PHS-393
 Ret. 3-70
                                       222

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              		SECTION 1	
               DEPAR  ^NT OF HEALTH. EDUCATION. AND W6LFABE
                        PUBLIC HEALTH SiHVICE
LEAVE BLANK
                                                       PROJECT NUMBER
	^SEARCH OBJECT.VES	fc EPA-IAG-D6-E772-BCO
NAME AND ADDRESS OF APPLICANT ORGANIZATION	
 New York  State Dept. of Health,  84  Holland Ave., Albany, N.Y.  1223? and
 Health Research, Inc., Roswell Park Div. 666 Elm St., Buffalo,  N.Y. 1426?
NAME. SOCIAL SECURITY NUMBER. OFFICIAL TITLE, AND DEPARTMENT OF ALL PROFESSIONAL PERSONNEL ENGAGED ON
PROJECT, BEGINNING WITH PRINCIPAL INVESTIGATOR
 Chester C.  Huang (127-34-3846) Principal Investigator, Senior  Cancer
   Research  Scientist, Springville Laboratories.
 TITLE OF PROJECT
 A Modified Host-Mediated Assay  Using Human Cells
USE THIS SPACE TO ABSTRACT YOUR PROPOSED RESEARCH. OUTLINE OBJECTIVES AND METHODS. UNDERSCORE THE KEY WORD;
WOT TO EXCEED 101 IN YOUR ABSTRACT.
        The purpose of this proposal is to develop a modified host-
 mediated assay system by  using cultured human lymphoid  cells as target
 cells  for screening chemical  mutagens and carcinogens.  Induction of
 chromosome damage will be used as an indicator of possible mutagenicity
 or carcinogenicity of a given compound.  First, the growth and
 cytogenetic  characteristics of several selected human lymphoid cell
 lines  will be studied in  vitro and after inoculation of such cells
 in heterologous hosts, second, effects on chromosomes of  human lymphoid
 cells  in host by several  known mutagens and carcinogens will be tested
 in this  modified host-mediated system and third, the mutagenicity
 and  carcinogenicity of several pesticides in common use will be
 evaluated by using the modified host-mediated assay developed.
 LEAVE BLANK
 Task:   ERR - 1.16
 Agency:  NIEHS
 Funding: $42,000 • 76
 Project Officer:  Dr. Fred de  Serres
 Eft. Completion Date:  1977
  NIM 3J8 (FORMERLY PHS
  ««. 1/73
                                   223

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               U.S. ENVIRONMENTAL PK31CCTIQN AGE.NCV
                NOTICE OF RESEARCH  PROJECT
                                                                         r>\\n .Vo.
                                                                PROJECT NO. (Do nut ux* this a

                                                                SSIE
     PREPARED TOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                EPA-IAG-D6-E772-BCO
TITLE OF PROJECT
Developmental Toxicology Indicators
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES Or PRINCIPAL INVESTIGATORS O« PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Robert L.  Dixon,  Ph.D.,  Chief, "Environmental Toxicology Branch
NAME AND AOORESS OF APPLICANT INSTITUTION

 National Institute of Environmental Health Sciences
 P.O.Box 12233, Research Triangle Park,  N.C.,  27709
SUMMARY OF PROPOSED WORK - il> Obj.-niv,.-*. (2) Approach, (*> Current Pljn» ind'or Prnjrci* 1200 word* or less. Omit connder.Ii.-i: daw).
   In the Smithsonian Science Information Exchange, liCTimaric* of work in pre^teia i(re exchanged with government and private agencies typ-
por'.lng re*earch and ar* forw:.rd«d to invcsticalorc who r«4-je«t such information. Yotfr surntn»f>- ia to be uied for theae purpot**.

     The human population now has a lifetime exposure to an increasingly large number
 of chemicals with incompletely defined biological activity.  Among the least adequately
 understood characteristics of .many of these chemicals is their potential toxicity to man
 at his most vulnerable stage of development-conception  to birth.  While the  more immediate
 transplacental effects such as abortion or teratogenlc changes  are relatively well studied.
 among  these agents,  the often more insidious and potentially more harmful lifetime effects
 have received little attention.  The great difficulty in correctly ascribing gestational origin
 to lesions  in the human population which are subtle or do not become-apparent until  later
 in life  makes laboratory and epidemiological Investigations in this area essential.  Ongoing
 studies seek to determine the postnatal lifetime toxic effects in rats of totigestational
 exposure to selected  environmental agents.
        PROFESSIONAL SCHOOL INVOLVED O
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR      DATE
   SUPPORT MCTHOD , O,,.<:l. cuir)    ^TASK NO.

                               ERR 1.17
     f 3;; A
* U'iC

$150, 000
                                      FOR 0FF 1CE USE_ONLY_
                                                PROJECT ornctR
                                               Dr. Fred de Serres
                                                RESPONSIBLE ORGANIZATION
                                                NIEHS
F.Y.   I NO. 0'' ruTu«C VE40S TC'IT«T|VCLY
       ASSUNLD OtTOSO CJHRFNT F.Y.
 76   '
                                                         STARTING DATE
                                                                             f.STIMATED COMBLETI2-.
                                                                             OA1E
                                                                               1977
tPA Form 5740-1 (7-72)     HCPLACt.S PH5 FOHM 166 ANO 51-SIE 76A WHICH MAY NOT 8C I
                                          224

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   Prepared [or th* ScioncB Informa-
   tion Exchange.

   Net for publication or publication
        U. S. Deportment of
HEALTH, EDUCATION, AND WELFARE
       PUBLIC HEALTH SERVfCG
                                                                   I PROJECT NO. (DO NOT USE THIS £r'ACE)
                                                                     EPA-IAG-D6-E772-BCP
                               NOTICE OF RESEARCH PROJECT    >	
TITLE OF PROJECT
ERR  2.1  Metabolism and  disposition of  selected radiolabelled hydrocarbons and  some of their
chemically reactive epoxides by the isolated, perfused rabbit lung and by solubilized, re-
constituted pulmonary biotransformation systems

ra$SfrABL%%%^^^^^^                               INVC5T,CATOR5 OR PROJECT DIRECTORS^) ALL OTHER

J. R. Bend, Ph.D., Visiting Associate,  Pharmacology Branch
R. M. Philpot, Ph.D., Senior Staff Fellow,  Pharmacology  Branch
 NAME AND ADDRESS OF APPLICANT INSTITUTION

National Institute of  Environmental Health Sciences, P 0  Box 12233, Res Tri Park,  NC  27709
 SUMMARY OF PROPOSED WORK-(.'On words or 1.5»-Omit Cwrficfeniiof dale.)
   In the Science InFormotion Exchange summaries of work in progress are exchanged with government and private agencies supporting research in
 the bio*tciences and are forwarded •- investigators wKo request such information. Your summary is to be used for these purposes.


The metabolism of pure,  radiolabelled unsaturated hydrocarbons of different types
 (aliphatic, alicy'clic  and polycyclic  aromatic) and of  their epoxicles will be  studied in
 the isolated, perfussd rabbit lung and in the isolated, perfused rnt liver.   Major
metabolites will be  identified and quantitated; the relative importance of epoxide
hydrase and glutathione S-epoxidetransferases as deactivation pathways for the
 chemically-reactive  epoxides will be  assessed.  Covalent  binding, if present, will
be quantitated in both liver and lung hotnogenates.  The effect of glutathione deple-
 tion  on this  covalent  binding will also  be measured.
Task:  ERR-2.1
PROFESSIONAL SCHOOL t*,,*eal, den,ol. eto.) WITH 1 SIGNATURE OF PRINCIPAL INVESTIGATOR
WHICH THIS PROJECT SHOULD BE IDENTIFIED \ f\ I S> /, ,
| yvh*, K>. rp-r-fl
DATE
DO HOT WRITE BELOW THIS LINE - FOR OFFICE USE ONLY
 SUPPORT!
        Mfs7i)r. Robert L.  Dtxon
METHOD 0!: SUPPORT (Check one)
DAiKii- , Staff 1 1 Neaotiotei
(lnl.o.:'..ru!) 	 1 Conliael
FUNDS OBLIGATED
$120,000
CUIJREMT I'.Y.
76
llliMPER
BETrONO
D Special
P.oioct Grant
D Research I | ClSer
Grant 1 	 1 (Sptcilv!
OF FUTURF YEARS TENTATIVELY ASSUTiEP
CURIiENl FISCAL YEAR
BEGINNI.JC DATE
FSIil'A1 ~~
1977
                                          225

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                                        SECTION 1
                  DEPARTMENT OF HEALTH, EDUCATION. AND 1V5LFARE
                           MJSUCWALTM S6BVICE

                         RESEARCH OBJECTIVES
                                                                       LEAVE OLANK
                                                               PROJECT NUM8EH
                                                               • EPA-IAG-D6-E772-BCP
 NAME AND ADDRESS OF APPLICANT ORGANIZATION

 The University of Korth Carolina at Chapel  Kill,  Chapel  Hill,  North  Carolina 27514

 NAME, SOCIAL SECURITY NUMBER. Cf rICIAL T.T-.i. A\o DECARTV.sNT C? ALL PROFESSIONAL PERW3NNEL ENGAGED ON
 PROJECT. 6EG1NNINS WITH PRINCIPAL INViSTISATCS

 Lorcan A. O'Tuama,  M.D., 385-54-9154, Ass't.  Prof,  of Kadicine (Neurology) and Pediatrics
        and Research Scientist, Biological  Sciences Research Centep
 John T. Gatzy, Ph.D., 159-30-3973, Assoc.  Prof, of Pharmacology
 C.S. Kim, 400-72-1617, Graduate Assistant,  Pharracology
 TITLE OF PROJECT
 Regulation of Neural Distribution of Lead _
 USE THIS SPACE TO ABSTRACT YOua PSOrCSsi; =.=Si AHCH. OUTLINE 03.iCTIVES AND METHODS. UNDERSCORE THE KEY WORDS
 (NOT TO EXCEED 10) IN YOUR ABSTRACT.

Factors regulating the  entry and  distribution of inorganic lead in the nervous system
will  be studied under control  ani selected abr.oml conditions.  In the guinea pig,
1n vivo CSF perfusion will  quantitate the dis3ppeerir.ee rate of J10Pb and 't5Ca across
the blood-CSF barrier.   The. uptake of zi°Pb and '->-& across the blood-brain barrier
will  be measured by an  indicator  dilution technique.  These measurements will be cor-
related with  levels of  lead and calcic attained in brain, meninges, choroid plexus and
                                                                            l? ecMt
ependysa.   These indices  will  is determined for control animals and for animal
lead-poisoned.   The affinity of the neural tissues for lead and calcium in the absence of
an intact barrier will  be assess&i by measuring in vitro uptake and release of 21cPb
and ''SCa.   This will  be determined under control ccndtions; after inhibition of general,
oxidative and glycolytic  r.etabolis-; after changes in nedium electrolyte composition
and after exposure to reagents that act as Hoards.  An effort will be made to distin-
guish solute accumulation due  to binding within neural tissue from that due to movenent
across the tissue using excised b-jllfrog choroid plexus and meninges which can be
irounted as "polar" membranes,  allowing direct measurement of transepithelial flux.  This
parameter will  be studied in control and acutely poisoned frogs and contrasted with
the results of in vitro uptake ar.d release experirsrts in the san:e species.  Tne be-
havior of 109Cd. a non-n£'jrotoxic r.atal, will also ":e observed in several of the
above experimental situations, so as to suggest patterns of uptake and distribution
that are not correlated with neurotoxicity.  These studies wiH (a) establish how  the
disordered' flow of lead across neural barriers that -.,3 have noted in lead encephalo-
pathy contributes to its  pathocer.ssis; (b) allow develop-ent of predictive tests for
neural toxicity of potential toxins and pollutants by testing their effects on
barrier function.
 LEAVE BLANK
 Task:  ERR-2.7
 Agency :   NIERS
 Funding:  $65,000 -  76
 Project  Officer:  Dr.  Robert  L.  Dlxon
 Eft.  Completion  Date:  1977
 PHS-395                            ""      PACE 2
 Rev. 3-73
                                   226

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                 DEPARTMENT OP HEALTH, EDUCATION. AND WELFARE
                           PUBLIC HEALTH SERVICE

                         RESEARCH OBJECTIVES
                                                                       LEAVE (JLAMi;
PHQJECTNUMBtR

EPA-IAG-D6-E772-BCP
NAME AND ADDRESS OF APPLICANT ORGANIZATION

     The University of South Dakota, Vet-million, South Dakota 57069
NAME. SOCIAL SECURITY NUMBER. OFFICIAL TITLE. AND DEPARTMENT OF ALL PROFESSIONAL PERSONNEL ENCAGU(5"oS~
PROJECT, BEGINNING WITH PRINCIPAL INVESTIGATOR

     Frank 0. Brady, 280-40-3462
     Assistant Professor
     Department of Biochemistry
TITLE OF PROJECT
     Function of Hetallothionein  in Heavy Metal Metabolism
USE THIS SPACE TO ABSTRACT YOUR PROPOSED RESEARCH. OUTLINE OBJECTIVES AND METHODS. UNDERSCORE THE KEY '.VGfU
(NOT TO EXCEED 10) IN YOUR ABSTRACT.
      The low molecular weight, cysteine rich protein, ffetallothionein will  be studied
 under a variety cf conditions in order to elucidate its function in heavy metal  metab-
 olism.  Its involvement in the mechanisms of incorporation, metabolism, deposition
 and turnover of hazardous toxic metals, which are becoming increasingly prevalent in
 the environment as byproducts associated with various ensrgy related technologies,
 will be elucidated.  Specifically, the focus of these studies will  be on the mechan-
 isms of action and sites of localization and transfer of heavy metals in perfused rat
 lungs, and possibly livers and kidneys,  (both in vivo and ex vivo}  and in rats  (bofh"
 adults and neonates).  The heavy metals of interest in this study are zinc, cooper.
 cadmium, mercury, nickel. and thallium.  Initially, these will be studied"	
 as a preliminary to more important experiments which will involve the study of inter-
 actions of two or more of these metals, e.g., a situation which is more likely to
 occur under environmental conditions.  The goal of these studies is to establish
 whether metallothionein is functioning in detoxification of toxic heavy metals or
 has another role in the normal metabolism of essential heavy metals, the presence
 of toxic heavy metals serving to interfere with these normal processes.
 IEAVE BLANK

Task:   ERR - 2.8
Agency:  NIEHS
Funding:   $44,000 -  76
Project Officer:  Dr.  Robert L.  Dixon
 Est.  Completion Date:   1977
 PHS-398
 ftov. 3-70
                                   227

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  Prepared (or Iho Science Informa-
  tion f.xchonge.

  Not for publication or publication
  reference*
        U. S. Department of
HEALTH, EDUCATION, AND '.VELPARE
        PUBLIC HEALTH SERVICE

NOTICE OF'RESEARCH  PROJECT
                                                                    PROJECT NO. 100 NOT USE THIS SPACO
        EPA-IAG-D6-E772-BCP
TITLE OF PROJECT
                   Environmental Teratology Information Center (ETIC)
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED ON THE PROJECT.

Robert E. Staples, Ph.D., Research Physiologist,  Environmental Toxicology Branch

Interagency Agreement, Oak Ridge  National Laboratories  (Contact:  John S.  Wassom)
NAME AND ADDRESS OF APPLICANT INSTITUTION

National Institute of Environmental  Health  Sciences, P 0  Box 12233,  Res Tri Park,  NC  27709
SUMMARY OF PROPOSED WORK-(200 words or less-Omit Confident^/ Jala.)

   In tho Science  Information  Exchange  summaries of work in progress are exchanged <
tha bio
                                                            ith goveri
                                                                  intent and private agencies supporting research i
 NIEHS is establishing a computerized information system for teratology to meet  the need
 of government  agencies and  scientists-at-large for knowledge of the teratogenic potential
 of environmental  components.   Data on warmblooded animals judged  to be useful for
 determining  the teratogenic potential of  environmental  factors v/ill  be extractedjn
 tabular form.   Information  will  be collected from published and unpublished  studies,
 whether the  result is positive or negative.   On-going  studies will  also be included.
 Task:   ERR -  2.9
 PROFESSIONAL 5CHOOL (nedico/, denial, tic.) WITH
 WHICH THIS PROJECT SHOULD BE IDENTIFIED
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                        DATE

                                                      August 22,  197
                            DO HOT WRITE BELOW THIS LINE - F&.TOFFICE USE ONLY
 SUPPORTING AGENCY
     NIEHS/Projeet  Officer;  TYr. Bnhoyf T
 MUTKOD OF SUPPORT (
    DAjenc, Stoff       I  j Negotiated
    (Inlronuroi)        I - » Contract
      II Sprclol
      I	1 Project Gri
DReseot
Grant
a Other

(Specify)
FUNDS OBLIGATED CURRENT f.t.
0 76
NUMBER or TUTU
BEYOND OJRRrH
<<£ YUARS TLHT\
f ISC.AL YE ;K
TIVELV M'.URED
BEGINNING DATE
ESTIMATED
COMr-LtTlO.-i PATE
1977
 HiH-19*16 (FOnMEtlLY
                                            228

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               U.S. ENVIRONMLIITAL PhOTCCTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                           f'tir*rt A
                                                                         ovn A'O.
                                                PROJECT NO. (no nut UAC rn(

                                                55IE
     PREPARED TOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                 EPA-IAG-D6-E772-BCP
        FROJECT
_____ Mechanisms  of heavy metal toxicltv
GIVE NAr-'ES. DEPARTMENTS. AND OFFICIAL TITLES Or PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
    James S. Woods,  Ph.D., Pharmacologist,  Environmental Toxicology Branch
    Bruce A.  Fowler,  Ph.D.,  Senior Staff Fellow, Environmental Toxicology Branch
HAMC AND ADDRESS OF APPLICANT INSTITUTION
    National Institute of Environmental Health Sciences,  P.  O. Box 12233, Res.  Tri. Park,
    N.C.  2-7709
 SUMMARY OF PROPOSED Y.'ORK - U) Objective. \2) Arpreacfi. (3) Current PLtns imrt'or PrOirt-ii ^200 words Of :e»». Omit confidence: data).
   In the Smith*onion Science Information Cjirhan^c, aumniariek ot worit in prc;rc»» are exchanged wi[h gowcrnmcni and private sgpnctcs sjp-
     r#t«»rch *nd jr« rorw;«rij«d to invcsticotars who r«o/je»l cuch infornuiion. Your summary i* to be uied for thcsr purpose*.
                                          b^
        Animals of several species are to/chronically exposed to low levels of selected trace
    metals of environmental importance.  The pretoxic effects of these agents on clinically
    important metabolic parameters of organ function'will be identified & quantitatively
    assessed.   Particular attention will be paid to effects on hematopoiesis and other mito-
    chondrial functions of the liver,  kidney and erythropoietic organs of exposed animals
    Further mechanistic studies and the application of these findings to the design of
    predictive  tests of potential clinical utility will be performed in intramural programs
    directed  by the principal investigators.
 1'Jt'rir.7V PftOfr GSSiONAL SCHOOL INVOLVED (M
 tt"nt..l. ffc.j
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
                                        fOR OFFICE
                                               "
    SUPPORT MLTMOD -'C«i-ft on*-
  $60, 000
76
                                    ERR 2.10
                                PROJECT OFFICtR
                                Dr.  Robert L. Dixon
                                RESPONSIBLE ORGANIZATION
                                NIEHS
                                                           STARTING DATE
                                                                               rSTIMATtO COMPLET1C
                                                                               DATE
                                                                                 1977
 IPA Fo,m 5740-1 (7-73)    RCPLACES PHS FORM 160 AND SI-5IE 76A WHICH MAY NOT BC USED.
                                           229

-------
              U.S. ENVIRONMENTAL PROTECTION AGEWCV
               NOTICE OF RESEARCH PROJECT
     PREPARED TOR THE SMITHSONIAN SCIENCE INFOP.MATIOH EXCHANGE
TITLE OF PROJECT
                                                         Farm A
                                                       OMfl.Vo.
                                                              PROJECT NO. (Da net utr Ha* .pace,

                                                              SSIE
                                                EPA-IAG-D6-E77 2-BCP
   Biological Effects of 60 Hertz Electric Fields
GIVE KAMES. DePABTMlNTS. AND OFFICIAL TITLES OF PRINCIPAL IN VCSTIOATORS OR PROJECT DIRECTORS AND AU. OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   A. A. Marino, Ph.D., Principal Investigator,  Orthopedic Research 167-32-4100
   R. O. Becker, M.D., Medical Investigator, Orthopedic Research  098-14-7718
   I. A. Spadaro,  Ph.D.,  Research Biophysiclst, Orthopedic Research 065-34-4594
NAME AND ADDRESS OF APPLICANT INSTITUTION
    Research Foundation of SUNY
    P. O. Box 7126, Albany,  N.Y.  12224
                                 SUNY Upstate Medical Center
                                 750 East Adams St., Syracuse,  N. Y.  13210
SUMMARY OF PROPOSER V.ORK - (1) Ob.M-tftHvs. (2) Approach. (J) Current PLjns nRd/or Profttls tJOO wards or leas. Omit confident!.?: data).
   In the Smithsonian Science Information Ekrfiance. sumtniiriee of work in prepress are czcnarvevd with f ovenwnent and private acenelea »ap-
porting research and art forwarded to investigatora who request such information. Your summary ia to te use* for thea* aurpoaea.
       60 hertz electric fields arising from electric power transmission- lines are ubiquitiousl f
    present  in the environment.  The strength of-such fields varies directly with the operation
    voltage  of the transmission  line and inversely with distance  from the line.  Biological
    effects attributable to low "frequency electric field exposure have recently been described
    notwithstanding earlier work minimizing the biological significance of such fields.   Pre-
    liminary results obtained in our laboratory show that a 60 hertz electric field of 150 volts/
    em is a  biological stressor.  That is,  field exposure alters normal growth in rats & mice
   'and produces changes in the levels of serum hydroxy-corticosterone and serum proteins.
    This  project involves the systematic study of these phenomena in greater detail.

       Presently, the human health hazard associated with exposure to 60 hertz electric
    fields is known. There have been  no systematic studies of such effects and consequently
    there are no federal or  state standards  for permissible  non-occuoattonally related
    exposure.  Continuing  our initial work,  we propose the following experiments to evaluate
    the biological effects of 60  hertz_electric fields at 150 volts/em:
    1.  The effect in rats on serum  hydroxycorticosterone,  triglycerides,  total proteins & the
      effect on growth,  tissue  structure and food and water consumption.
    2.  The  effect on reproduction in mice.
    3.  The  effect in rabbits of acute & chronic  exposure.

       The  experiments will be repeated as a function of field strength & frequency.
 iam riFY PROFESSIONAL SCHOOL INVOLVED f.v«j.e.,/
 H-nt.,1. ,lf.l
                         SIGNATURE OF PRINCIPAL INVESTIGATOR
   SUPPORT MCTHOO iCIu-rt ana!
   CS OOLIG*TF.O
$32,000
76
                                      FOR OFFICE USE ONLY
                              ERR 2.12
                      NO. O»' F-UTJRC
                                               PROJECT OFFICER
                                               Dr. Robert L, Dlxon
                               RESPONSIBLE ORGANIZATION
                                NIEHS
                                      TC'lTATIVCLY
                        .
                      ASSUHCO DEVONO CURRENT F.Y.
                                                        STARTING DATE
 EPA Farm S740-1 (7-73)    REPLACES PHS FORM 1(0 AND SI-SIE 7SA WHICH MAY NOT BC USEO.
                                                            F.STIMATED COMPUCTI9*.
                                                            DATE
                                                                                1977
                                             230

-------
   Pr«por«d fur th» 5ei«nc« Inlormo-
   tten Hxchengv*

   N«l (or publication or publication
   rvfironco*
                                          U. S. Department of
                                 HEALTH. EDUCATION, AND WELFARE
                                         PUBLIC HEALTH SERVICE

                                 NOTICE OF  RESEARCH PROJECT
                                                                          PROJECT HO. (00 NOT USE THIS iPACF.)
                                                                         EPA-IAG-D6-E772-BCQ
 TITLE OF PROJECT
ERR-3.2
Respiratory Tract Deposition  ftodels
                                                     INVESTlCATOaS OR PROJE
                                                                                         ALL OTHER
 Project  Director:  Otto 6. Rnafasra,  Ph. D.,  Lovelace Foundation  for Medical Education
                       and Research

      iirt  Officor-:   Phillip tJ. 1'alsh, Ph.  P., HIDIS
 NAME AND ACDRE1S OF APPLICANT INSTITUTION


jj&t1ongT_Iiistjt:^to_o-f  Eiiv'rcrimnt.ijl'  llealtii  .Sciences,, r.0>_l!c_x 12233, jlas..  T ;.-•;.  p^rk,  !!.C_,_ "770:
 S'JJir.ARV Oi1- PijOPOSED V/'l:;:: .. (?i!0 Win/i tr/Mf-Ooid Co-.'focn;ful Jn.-o.) ""              ""
 the b:e»£ci£nc:
                                     wha riqu
                                                                        be yij%' ^i' Huso f .•<
*!'!•(:_ pn.-ii)" :-:.-'!;.^! v.'-;"  ire:   (<}  l'i  cnnrl'^ct !'!>;/::i.:Kl *-•;'.:}?, of  ti:s; i-L-,r;piiT:i;'v.v  v.":^'~.-.-  ::•,'
!iia>i «;;J ::-';v;..'i-'i  ;r.';:.:-.'5  *:.- •.•':•! f.~; (?)  to r,v;'^J!.:.'£ J^;;M:;i i,:':^ o? ac;v,si>U  j..s,-  i;;:.:^1  o..-; 0.-.';1
fcrlcrflti iiw.n.v:tar  in ti.e  tKOiio i 3 •  (''.}  to ^ai,ftri,:i!is thft fc^o'ltlcn  of sc'lectoJ i/iij'tlc'ie s1:.:u
in  animals  antl in i.iati if practical;  (4) to  cisvalop a theoretical  model  of deposition in the
lung based  on the ebovc results; end (5) to evaluate the  physical-theoretical model in  the
fiend,
PROFESSIONAL SCHOOL fnW/col,
WHICH THIS PROJECT SHOULD Bl

SUPPORTING AGENCY

E Off
(/en>«', etc.t WITH
IDENTIFIED
DO HOT
Leer: D
SIGNATURE OF PRINCIPAL INVESTIGATOR
DATE
WRITE BELOW THIS LINE - FOR OFFICE USE ONLr
T. Larry 6. Hart
                                                             ^                	
                                                               1 R.ieorcl,         1 OlS.r

                                                                   "              ' P"?
    DA,',n«» Sf,rt'  '     r"1 N=8°»<"^        I   I SP"'jl
    !l'.l,.7j,.-,-,')         I..J C'.ntrnel       	L_J^r^»<-! t IOM  _	

^Owf'"^''-"-"  |L,Y,,i;.tJ(l,!V,.vf,SCA1.,.EAfl                         		^in".
                                                 231

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                                        SECTION 1
                 DEPARTMENT OF HEALTH. EDUCATION. AND WELFARE
                           PUBLIC HEALTH SERVICE

                         RESEARCH OBJECTIVES
                                                                       LEAVE PC A
                          PROJECT NUMU£H
                          ;EPA-IAG-D6-E772-BCQ
NAME AND ADDRESS OF APPLICANT ORGANIZATION
Harvard School of Public Health
665 Huntington Avenue, Boston, Mass.  02115
NAME. SOCIAL SECURITY NUMBER, OFFICIAL TITLE, AND DEPARTMtNT Of ALL PROFESSIONAL PERSONNEL ENGAGED OH
PROJECT. BEGINNING WITH PRINCIPAL INVESTIGATOR
Mary 0. Amdur      013-26-1512
Dwight W. Underhill 579-50-2490
Assoc. Professor of Toxicology
Assist. Professor of Envirbn.
       Health Engineering
                                                                      Dept.  of Physiology
                                                                      Dept.  of Physiology
TITLE OF PROJECT
         Factor Affecting Irritant Potency of Gases and Aerosols
USS-TTHIS SPACE TO ABSTRACT YOUR PROPOSED RESEARCH. OUTLINE OBJECTIVES AND METHODS. UNDERSCORE THE KEY WORDS
(NOT TO EXCEED 101 IN YOUR ABSTRACT.

We  propose to  examine  the jdint toxic action of  sulfur  dioxide and  ozone.   Concen-
trations used  will be  in the  range of 0.2 -  0.8  ppm of  each gas.  They will be
combined in  equal concentration as well  as in varying ratios.   The  criteria of
irritant response will be alterations in the respiratory mechanics  of guinea pigs.
The response to the combination will be  compared to previously observed changes
produced by  sulfuric acid.  We also plan to  study the uptake of sulfur dioxide by
wetted wall  tubes with and without, the addition  of aerosols.   We  plan to study the
solubility and reactivity of  sulfur dioxide  in solutions of various salts  which
have been  shown to  potentiate the biological response.
LEAVE BLANK
 Task:  ERR-3.3
Agency:   NIEHS
 Funding:   $69,000  - 76
 Project Officer:   Dr. Larry  G. Hart
       Completion Date:  1977
  • IH 353 (FOHM«i.Y PHS
                                           PAGE 1
                                 232

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                               PROJECT NO. (Do not ux* thtx *p»ce)
                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                 EPA-IAG-D6-E772-BCQ
 Respiratory Tract Deposition of Inhaled Aerosols
"GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

 C.P. Yu,  Professor, Dept. of Engineering Science, Aerospace Engineering &  Nuclear Eng.
 D'.B. Taulbee,  Associate Professor,   "       "         »           »             »
 Two Research Assistants (to be determined)
NAME AND ADDRESS OF APPLICANT INSTITUTION

 State University of New York at Buffalo
SUMMARY OF PROPOSED WORK - (1) Objective... (2) Approach. (3) Current Pljns Odd/or Projr.js (300 words or less. 0:ni< confidential data).
   In the Smithsonian Science Information Exchange, sutnnuirieB of work in proercsa ar« exchanged with government and private agencies sup-
porting research and arc forwarded to investigators who request tuch information. Your luminary ts to be used for theae purposes.

     Mathematical models  are to be developed for theoretical prediction of particle
 deposition and distribution along the respiratory tract system.  Specifically,  the following
 tasks are to be undertaken during the period of requested support:

     1.   Develop a mathematical model for deposition in  man at nose-breathing.
     2.  Recommend figures for the regional deposition in the human lung at nose  and
         mouth-breathing under various working conditions.  Emphasis will be given to
         fine particles  which are difficult to be removed from power plant emissions.
     3.  Develop a  mathematical model for deposition in smokers and patients with chronic
         obstructive pulmonary  disease.
     4.  Develop a  mathematical model for deposition in experimental  animals.

 The basic method to be used in the one previously developed.by the principal investigator
 and his faculty associate.
 IOEMTIFY PROFESSIONAL SCHOOL INVOLVED f.V
 
      OOLICATEO
 $49, 000
76
                                       FOR OFFICE USE ONj-jT
                                 ERR 3.4
                                PROJECT OFFICER
                                  Dr.  Larry G. Hart
                                                RESPONSIBLE ORGANIZATION

                                                   NIEHS
       NO. OF FUTL'RC YEABS TENTATIVELY
       ASSURED BEVONO CURRENT F.Y.
                                                         STARTING DATE
                                                                             LSTIMATEO COMPLETION
 EPA Form S7«M (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                           233

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              U.S. ENVIRONMENTAL PK31 ECTION AGENCY
               NOTICE OF RESEARCH PROJECT
     PREPARED TOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                        Fnrm Afff
                      OW/1 .\a  I'
                                                              PROJECT NO. (flo «of u*r this

                                                              SSIC
                                                                EPA-IAG-D6-E772-BCQ
TITLE OF PROJECT
  Compartmental Models for Body Burden of Pollutants
.IVE NAMES. DEPARTMCNTS. AND OFFICIAL TITLES OT PRINCIPAL INVESTIGATORS OB PROJECT DIRECTORS AND ALL OTHCS
'ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

  Allan H. Marcus, Associate Professor,  Dept. of Mathematics (R.  I.)
NAME AND ADDRESS OF APPLICANT INSTITUTION
  University of Maryland - Baltimore County, Division of Mathematics & Physics
  5401 Wilfcens Avenue,  Catonsville, Maryland 21228
SUMMARY OF PROPOSEn V.ORK - il) Obj.-tlix-v«. (2) Approach. C3) Current PUin* (ind'or Projrt** i200 words Of l«ss. Omit confidential: <N).
  In the Smithsonian Science Information Exchange, sumnwriea of work in pic;ie*s are exchanged wiih covernmenl anj private agencies t-jp.
pwrtinc research and arc forwarded to investigators who req/jcst such Information. Your summary is to b* used lev these purposs*.

      It is often possible to model the body burden of pollutants  as a mixed exponent
  moving average of the external pollutant dosage.  This model fails:  (a) when the pollu-
  tant occupies a significant  fraction of a  system  e.g. carbon monoxide,  (b) when an
  appreciable fraction of pollutant is retained in long-lived components e.g.  bone-seekers
  such as  lead.  A semi-Markov model for physiological  kinetics generalizes this model.
  By representing body burden as a stochastic integral of external dosage, it is often
  possible to estimate the frequency, duration, and parameters of other integral  exceedance.
  measures for  body burden,  thus to estimate the effects of environmental quality standards
  on body  burden variation.  Physiological kinetic models  for carbon monoxide, for the
  lead-calcium system,  and for cadmium-zinc,  will be estimated using  non-linear
  regression techniques for experiments (as reported in the literature) on uptake  and
  elimination in constant evironments.  Stochastic models will be developed for  external
  dosage of CO and lead,  and the  parameters of the exceedance measures of body birden
  estimated.  In this way it may prove possible to establish a better rationale for environ-
  mental standards  setting.
1'JfnriFr BROtESSIONAl. SCHOOL INVOLVED r.Vettic.,1.
U-r.l.,1. ..re.)
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
   SUPPORT METHOD i'Cfit-cX- onvl
       l- AI1CH GRANT
 $24,000      76
                            TASK NO.

                              ERR-3.5
                                      FOR OFFICE USE_ONLY	
                                               PROJECT OFFICER
Dr. Larry G.  Hart
                                               RESPONSIBLE ORGANIZATION

                                                 NIEHS
                      NO. OF ruTU^C VE*\R5 TC'lTATivCLY
                      ASSUhLD EIE.TCND CURRENT F.Y.
                                                        STARTING DATE
EPA Ion,, 5740-1 (7-7?)    RCPLACES PHS FORM I6G ANUSI-SIE. 76A WHICH MAY NOT BC USED.
                            LSTIMATED COM
                            DATE
                                                                               1977
                                          234

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               U.S. ENVIRONMLMTAL PhOT ECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                       own .\a
               PROJECT NO. (Do

               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
J1ITLE OF PROJECT         —^__	_—...
Trace  Element Deposition in Ambient Aerosol Inhalation
                                                               EPA-IAG-D6-E77 2-BCQ
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES Of PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
PNOFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

Winchester, John W. SS no.  322-22-5851, Professor & Chairman,  Depf. of Oceanography,
  Principal Investigator
NAME AND ADDRESS OF APPLICANT INSTITUTION
Florida State University, Tallahassee, Florida 32306
SUMMARY OF PROPOSED WORK - (1) objrclivoi. (2) Approach. (J) Current Pljn» and/or Proj!cj» i200 »orj« or Icsi. Ornll confident!*: ial»).
   [n the Smilheoniiin Science Information Cxrhar^c. summaries of work in prc.-Tc»ft arc cicnanet-d with government and private agencies »-F-
purlln* r*»«arch and jr« forwarded Co investigaiors who req-jett ftuch information. Your luminary ia to be used for thete purpose*.
    The response to inhalation of ambient aerosol particles from indoor and selected outdoor
environments will be investigated using high sensitivity  elemental analysis by proton in-
duced X-ray emission, PDCE.  The response may include both deposition of particles in the
respiratory trace and growth in particle size due to exposure to high relative  humidity during
breathing.  Both responses may depend on particle size and on chemical composition of the
particles and may be different for different component particles in a mixed aerosol.  The
different components may be distinguished by their different elemental composition, and
the respiratory response of each may be determined in  a single experiment.

    Samples will be taken by 5 stage  cascade impactor with fine  particle filter and will
provide resolution of particles < 0. 25 to >4 mm equivalent aerodynamic diameter.  Each
size range is analyzed for its elemental constituents by PTXE, including S,  CI,  K, Ca, Ti,
V, Cr,  Mn,  Fe,  Ni, Cu,  Zn,  Br,  Pb, Zr,  Cd,  and additional heavy metals if present in the
aerosol.  The nanogram sensitivity  of the PKE technique permits fine particle size resolution
at a sampling rate of 1 liter/minute  a^d requires of human subjects only 10 minutes or  less  of
breathing time per sample.  Experiments  are carried out using ambient aerosol  from different
actual environments and do not require the use of special tracer materials.  A major objective
of the research will be to standardize experimental conditions and develop a  compact  &
portable  sampling unit which can be used in more specialized medical tests of inhalation
response to pollution  aerosol  particles.
 UfNTIFY PFiOF ESStONAL SCHOOL INVOLVED Or
 J'-nl.,f, ,-rc.J
                                         SIGNATURE OF PRINCIPAL INVESTIOATOr)
                                       FOR OFFICE USE OriLY
    SUPPORT METHOD .C/u-cfc o/i*-,»
     j CQLIGATED
                                   ERR 3. 6
PROJECT OFFICER
Dr. Larry G. Hart
RESPONSIBLE ORGANIZATION
NIEHS
$55,700
                fTV.   I SO. O>' ruTL'T YEA"? TC'ITATivCLY
                                                        STARTING DATE
                            f.STIMATEO COMPLETI3",
                            DATE
                              1977
 tPA F.m 57(tM (7-72)    REPLACES F-HS FORM 166 ANO SI-SIE 76A WHICH MAY NOT B\l USED.
                                           235

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
 Regional Deposition of Inhaled Particles in Man
                                                                    ovn \o. MS-ROOM
                                                            PROJECT NO. (Do not uaf this apacvj

                                                            SSIE
                                                             EPA-IAG-D6-E772-BCQ
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED |N THE PROJECT.
Morton Lippmann, Ph.D., Medicine,  Associate Professor,  Dept. of Environmental Medicine
Roy E. Albert, M1. D.,  Professor,  Dept. of Environmental Medicine
Richard B. Schlesinger,  Associate Research Scientist,  Dept. of Environmental Medicine
Donovan B. Yeates,  Ph.D.  & Tai L. Chan, Research Scientists, Dept.  of Environ. Medicine
NAME AND ADDRESS OF APPLICANT INSTITUTION
New York University Medical Center
550 First Avenue,  New York,  New York 10016
SUMMARY OF PROPOSED V.ORK - (1) Objt cliv-.-s. (2) Approach, (3) Current Plans anri/or Progri
                                                                  >rjs or letft. Omit confident!*: data).
    The objective of this research program is to develop & refine realistic predictive  models
for particle deposition  efficiencies & patterns in the human tracheobronchial tree.  The
models will cover respirable particles of all sizes,  a wide range of constant &  cyclic
respiratory flows, and be applicable to population  subgroups as well as averages.  They
will be based upon available data from  studies on humans in-vivo,  and available data &
new data on the distribution of deposition in hollow bronchial casts.  The new studies will
be performed using -/-tagged monodisperse aerosols, twelve new bronchial casts which ex-
tend to 2 mm airways, new replicate large airway casts,  new multiple lobule casts of
airways< 2 mm,  and appropriate colllmated scintillation detectors.  A variable orifice  larynx
model will be constructed for the deposition studies with cyclic flows.  High resolution
surface density measurements will be made by counting the numbers of particles on
bifurcations and other selected cast surfaces  with  a scanning electron microscope. These
measurements will establish concentration factors  and  identify locations for the cells
with the highest exposures to inhaled particles,  thereby providing a basis for the depositior
components of an airway surface  dosimetry  model related to human  bronchial cancer risk.
       PROFESSIONAL SCHOOL INVOLVED .'
                                       SIGNATURE OF PRINCIPAL INVESTIGATOR
                                    FOR OFFICE USE ONLY
   SUPPORT METHOD '
                             ERR 3.7
                         1
 UN'j: C Q L (G A r

$67,763
76
                                             PROJECT OFFICER
                                               Dr.  Larry G.  Hart
                              RESPONSIBLE ORGANIZATION

                                NIEHS
      ASSURED EJulCNO CURRENT F.Y.
                                       STARTING DATE
E.STIMATEO COMPLETIC
DATE

  1977
EPA Form 5740-1 (7-72)    REPLACES PMS F3r,M 166 AND 5I-5IE 76A WHICH HAY NOT BE USED.
                                       236

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              U.S. ENVIRO'IMLIITAL PhOI CCTI2N AGCNCY
                NOTICE OF RESEARCH PROJECT
     PREPARED POP THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                      OMft .Vo.
                              PROJECT MO. (V3o r

                              SS1E
                                                              "l!PA-lAG-D6-E772-BCQ
 iTttoF pROJECTuevelopment 01 WMK Spectroscopic Methods tor'Characterizing tlpeciiic Binding
 (Electronic_&_Cwa1ent:BQndlna) MrtrlflS of Organ,r.s & Inorganics Associated with Nnn-Nuclg|ar
 IVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT aiR£
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

 Dr. J.D. McKinney, Supervisory Research Chemist,  EPCB, NIEHS; Dr. P.W.Albro, Researcl
 Chemist, EBCB,- NIEHS;  Dr.  R.  Cox, Visiting Scientist, Dept.  of Chemistry,  University
 of Georgia
NAME AND ADDRESS OF APPLICANT INSTITUTION

 National Institute of Environmental Health Sciences,  P.O. Box 12233,  Res.  Tri. Park,
 N.C. 27709
SUMMARY OF PROPOSfR V.OP-C - (1) Obj
  [n the Smithsonian Science Information C
... (2) Approac!,. HI Curcnl Pljns and/or Pt
 g«. sunisiarir* of work in pro^rrts ar« cxrhn
                                                            :t»a i200 *orj> or less. O:nlt confident]
                                                            v«d with covcrnmcr.t and privatv agrncitfs
 (1) Objectives:  To isolate & identify on a molecular level the specific binding site(s)
 in body tissue and fluid for the highly toxic isomers in the chlorinated biphenyl, dioxin,
and furan classes and compare with selected members of the polynuclear aromatic hydrocarbc i
classes and other related planar molecules; to study metabolic activation using selected
non-radioactive  labeled 13C-benzo(a)pyrene derivatives and fluorinated isosteres of selected
compounds as mechanistic probes; and to explore the usefulness of selected metal nuclei'as
nuclear magnetic resonance (NMRJ probes for the sites and nature of their binding interaction
in body fluids and tissues.
(2) Approach: High resolution multi nuclei NMR using specifically labeled (  C, F19, 2H, et,
compounds where possible will be used as the primary tool for studying these complex mole-
cule interactions of biological significance.
(3) Current Plans:  The initial plans are to develop a multi-nuclei NMR capability and deter-
mine the advantages and disadvantages of various nuclei as mechanistic probes   The early
work will use various purified biopolymers and their monomers -as models and would proceed
to various intracellular organelles isolated from  biological systems.
        P^Or rlSSIONAU SCHOOL INVOLVED i'.v/eJic.J.
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
   SUPPORT Mf.TMOC i'C/M-i-1- ftp,1   j TASK NO.

                                ERR 3, 8
                                      FOR OFFICE USE OIM-Y	
                                             """PROJECT OFFICER
                 Dr. Larry G. Hart
                                               RESPONSIBLE ORGANIZATION

                                                NIEHS
  fiCj COLItiArpD
                 76
                        .
                      ASSUMLO ut^oNO CURRENT F.Y.
                                            F STIMATf.O C
                                            DATE1977
 IP* r,,m S740-1 (7-72)    ntPV.ACr.5 PHS FORM 166 AND SI-SIE 7CA WHICH MAY NOT 8E USED.
                                          237

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               U.S. ENVir»ONMinTA,L PKO1CCTIC" AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Farm A
                                                PROJECT HO. (Oa f
                                                SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                  EPA-IAG-D6-E77 2-BCR
   LfffectsJofTenergy-related pollutants on female reporductive tract function
&IVE NAMES. DEPARTMENTS. UNO OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
  George W.  Lucier,  Ph.D.,  Research Chemist,  Environmental Toxicology Branch;
  John A. McLachlan,  Ph.D., Developmental Toxicologist, Environmental Toxicology
  Branch
 IAME ANO ADDRESS OF APPLICANT INSTITUTION
  National Institute of Environmental Health Sciences,  P.O. Box 12233, Res. Tri.  Park,
  NC 27709
SUMMARY OF PROPOSED HORK - (I) Objrrlivvl. 
-------
               U.S. ENVIRONMENTAL PhOlECTICN AGENCY
                NOTICE OF RESEARCH PROJECT
                                         PROJECT NO. » nvt ua«* thin
                                         ssie
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                  EPA-IAG-D6-E7 7 2 -BCR
     OF PROJECT
  Effects of 60 Hz fields on the mammalian central nar -vous system
GIVE NAMES. DEPARTMENTS. ANO OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AHO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Donald I. McRee,  Ph.D.,  Mechanical Engineer,  Environmental Biophysics Branch
 W. Ross Adey, M.D., Professor, Anatomy and Physiology.  Director of Space Biological
 Laboratory,  Brain Research Institute, UCLA (Contractor); S.M.Bawin, Ph.D., Space
 Biological Lab., UCLA (Contractor); R. Gavalas-Medici. Ph., D., Space Biological Lab,:UCLA.
NAME ANO ADDRESS OF APPLICANT INSTITUTION
 Nat'1 Institute of Environmental Health Sciences, P.O.  Box 12233,  Res. Tri.  Park,
 N.C. 27709
SUMMARY OF PROPOSED WORK - (1) ObjrctiVfl. (2) Appreaeli. (3) Current Pljni unit/or Pr3jr..s (300 word* or !««.. Oir.it con(idrnii»: daU).
   In Ihr Smllhtoninn Scivncr tn/ormutlon Exchnnee, ciunniAri** of worlc irt proeref* arc f xrhancvd with covernment and privatr acrncUs lur-
     r*«««rch and ar* faffwardvd to inv«ati«ator» who Mqucat auch bifoffnation.  Your summafy ia to b« uinl tor thea* purpoaan.
 The objective of this research project Is to determine the effects of 60 Hz fields from
 high voltage transmission lines on the central nervous  system of mammals.

 Specific studies to be accomplished Include:

 1.  Effects on biorhythms in rats based on general activity measurements.
 2.  Effects on urinary metabolites  and their correlation with biorhythms
 3.  Effects on   Ca.^*" efflux from intact cat cerebral cortex.
     IFV Pf
-------
Pr»pnr»d for the Sc
lion Exchange.
Not Tor publication

«ne* Infarrr
or publicist'

O"
on

                                           U. S. Department of
                                  HEALTH, EDUCATION, ANU WELFARE
                                         PUBLIC HEALTH SERVICE

                                  NOTICE OF RESEARCH  PROJECT
                                                                         PROJECT KO. (DO HOT USE THIS SPACfc)
                                                                         EPA-IAG-D6-E772-BCR
 TITLE OF PROJECT

ERR  4.5  Respiratory and cardiovascular functions  in,pollutant exposed animals


 GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
 PROFESSIONAL PERSONNEL ENCAGED ON THE PROJECT.


L". W. Van Stee, D.V.K., Physiologist,  Environmental  Biology and Chemistry Branch
 NAME AND ADDRESS OF APPLICANT INSTITUTION


|ja!-.iqn?.l Inr.tUuta of Environments^  Health Sciences, .P_Q_B^x_.1^3_.. .j
 i'juMARr or pROfOJrr. '.VO.-IK -uw ••• ..,.js"or ;«„ .. o.-,.ii c^.-.fitWio) ck-c.)
    In the Sci-ince ln!t '.i; jlion fix-chon^ - • i-jrjrrioi 'e3 of •*g rasegrcS in
A ?:;,vi;i"';.:-5!;f.i' i.-.s-'iiod hni-  'v.;ii viavclo^ed  for t.!u  diiLonn-ina'^;!; of !'•••; ar,J S-T  i i:\.-r va'is,
(JRS  cii'i-fttiovis  ::,-:d iiftart r; lo.   A d'icnts'i piicc?s5i!»ri  csci Vlc?uspa  is Liso-!  in c;;;;;;.! irvHcn
'.,'ith 2; proyrapciabic  electT'or.ie calculator.   T!ia user sca;i.>  KCGs previously raccr-.larJ on
FM taps.  Visually identified  waveforas are  held in  the display by a s inn la keystroke.
Ci'rsc-rs ara  th-.Ti placed nn  the v/nvflforn v.'ith a;'dif.io"nl ksvstroke;.  Pr^nra"; axec-'tion
 Task:  ERR-4.5
 PROFESSIONAL SCHOOL ta-rffcn/, rfcni-./, «fc.l WITH
 ft'HICH THIS PROJECT SHOULD QE IDKilTIFIEU
                                                                     	
                                                                    VESTICATOR
                                                                                            DATE
                                                                                            10-20-7C
                              DO NOT WRITE BELOW THIS LINE - FOR OFFICE USE ONLY
 SUPPORTING AGENCY
	NIEHS/Project  Officer:   Dr.  Robert^L.  Dlxon
 r.tTK^D CF S-JFPOn i'O'isk o-ei
 ,   | *;»«., S'o'f       r~) M.5»
 I	1 (l-,l,Sr...,rol)       l_l Civ'

 FUMU5 uSi.lOATLi' Car.riLNT F.Y.
  $75,000            76
                                       jI sr«=iol
                                       L	1 Project Gt
-------
  Pr»p:;'c:.:;•• cH .-.•;•;•.;<•,
 i!';:i  •.'. rC'Xvl-.i ;••!).;:•  cf-'.'Lo:. ! :•-."'.;/-, ide Or- vari:us  parti cul ate:.;, and  to sulfur'it: ;;cic5
 <-:>oso"l to tic-tennir.j the effect of these pollutants on develcpi'iGiit of tha concsptus.
 'he offspring arc?  examnsd just before birth  for  the presence  of  external and  intern?.!
Task:   ERR-4.6
FfcrtPiSSIONAL SCSnCL tmxn-.cl, -Jiit?!. t^..) WITH
                                           SIGNATURE OF PXItlCIPAL IHVCSVI3ATOR
                                                                                      DATE
          ACEHCV


   ''''    '
                            DO HOT WRITE BELOVI THIS LINF- ^OffOFFICE USE ONLY
     __   I      MmiS/PtpJect_0fficerj	Dr. Robert L.  Dlxon	

D  L:^'
ru-r.- ;• <••-•• :<-,•.;=.:> cu

$100,000
                     76

                                                                                    1977
                                              241

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                                         SJ-CTIOM I

                  Of FARTMENT OF HEALTH, EOUCATiON. AND WELFARE
                            PUBLIC HEALTH 1C n Vice

                          RESEARCH OBJECTIVES
                       LEAVE BLANK
                PROJECT NUUBER

                
-------
                 OEPAflTMENT OF HEALTH. EDUCATION, AND WE LFAI1E
                           PUULIC HEALTH f.CRVICt
                         RESEARCH OBJECTIVES                 EPA-IAO-D6-E772-BCR
NAME AND ADDRESS OF APPLICANT ORGANIZATION

Stanford University    Stanford, California 94305
                                                                       IEAVC IJLANK
                                                               fROJEC"
NAME. SOCIAL SECURITY NUMBER, OFFICIAL TITLE. AND DEPAR IMENT OF ALL PROFESSIONAL PERSONNEL ENGAGED ON
PROJECT, BEGINNING WITH PRINCIPAL INVESTIGATOR
       S. David Holtzman, M.O., Ph.D.
       329-34-6056
       -Assistant Professor, Pediatrics and Neurology
       Head, Division of Pediatric Neurology
 TITLE Of PROJECT
             Lead toxicitv and energy metabolism in  iircnaturp drain
USE THIS SPACE TOABSTRACT YOUR PROPOSED RL'SfcARCH. OUTLINE OBJtrTIVES AND ML THODS. UNDERSCORE THE KEY WORDS
(NOT TO EXCEED 10) IN YOUR ABSTRACT.
    Lead  is a ubiquitous toxic pollutant.  The most serious manifestation of pediatn'c Iped
poisoning is an  acute  encephalopathy.   In addition, the  rising burden of environmental lend
may be producing  significant brain damage, without overt encephalopathy, in yotmg children,
In  the unborn fetus, and the neonate.   Pathologic studies suggest that lead produces edema
and capillary changes  at a  "critical" time in the immature brain of the human and in a rat
model  of  lead encephalopathy.  This  "critical" period in the rat contains many age-dependent
Changes in energy metabolism including  activities of the electron transport chain (ETC) as
described by this investigator and others.  Lead does act on the ETC in other tissues.  How-
ever,  there are  no studies  in immature  brain of lead effects on the ETC, a probable basic
step  in the pathogenesis of lead  encephalopathy.
    Preliminary  results are presented on effects of lead on oxidative phosphorylation in im-
mature rat brain  mitochondria.  Within  2 days of feeding lead to 2 week old animals, respira
tion with NAD-linked substrates is uncoupled, reflecting an increased state 4 rate.  During
the subsequent 2  week  pre-encephalitic  period of lead f'erJings, both state 3 and 4 rates be-
come  increasingly depressed.  Cytochrome oxidase activity -.hows the same changes.  These ef-
fects  are more significant  in cerebellar than in cerebral U^niisphere mitochondria.  Impor-
tantly, these effects  of lead occur  earlier than previously reported changes in brain fluid,
electrolytes, and morphology.
    Considering  the preliminary results and observations outlined above, investigations are
proposed  based on these hypotheses:  a)  the primary effect of lead in developing F/rain is en
energy metabolism; specifically on sites in the ETC; and b) this1 effect is basic to the tox-
ic  effects of lead.  Experiments  are designed to delineate the sites and mechanisms of actioi
of  lead to learn  more  of the properties of the ETC in Immature brain and of the p^thogenesis
of  lead encephalopathy.  Younger  animals will be studied to delineate'potential effects of
lead on the brain of the human fetus and neonate.	

 LEAVE BLANK
Task:   ERR-4.8
Agency:   NIEHS
Funding:  $62,000 - 76
Project Officer:   Dr.  Robert  L.  Dixon
 Est.  Completion  Date:   1977
 PHS-3'jfl
 Rev. 3-70
                                         243

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                	SECTION i	
                 DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE
                           PUBLIC HEAUTH SERVICE

                         RESEARCH OBJECTIVES
        LEAVE BLANK
PROJECT m.'.'::iiri
 EPA-IAG-D6-E772-BCR
NAME AND ADDRESS Of APPLICANT ORGANIZATION

 University of California, Departnent of Chemistry,  Davis,  California  95616
NAME. SOCIAL SECURITY NUM8ER. OFFICIAL TITLE, AND DEPARTMENT OF ALL PROFESSIONAL PERSONNEL ENGAGED ON
PROJECT. BEGINNING WITH PRINCIPAL INVESTIGATOR

 August H. Maki       078-22-k5l*9    Professor              Chemistry

 Steve Siegel         013-38-7607    Research Assistant     Chemistry

 Tiao-te  Co          256-96-6936    Research Assistant     Chemistry

                                     Postdoctoral Fellow    Chemistry


TtTLH OF PROJECT                                                 '            '
 Binding of CK<.Hg  . an Environmental Hazard,  with PSA __ ,
USe THIS SPACE TO ABSTRACT YOUR PROPOSED RESEARCH. OUTLINE OBJECTIVES AND METHODS. UNDERSCORE THE KEYWORDS
WOT TO EXCEED 101  IN YOUR ABSTRACT.

      We • intend to deteraine the extent to which  PHA. of chroaosones binds aljtyl and
 aryl mercury in living cells.  Also, we wish to obtain information on the molecular

 level concerning the nature of the complexes.  Hie method to he used ia a

 spectroscopic one, optical detection of magnetic resonance,  Oder, by means of

 which magnetic resonance transitions in photoexcited triplet states are detected

 optically.  A heavy aton effect caused by mercury binding to an aromatic chromophore  such

 as a heterocyclic base of DMA makes the resulting triplet state a highly radiative trap

 which is especially sensitive to odrar.  The odmr method thus selects the mercury-

 perturbed chromophore which then can be identified by  the magnetic resonance frequencies s

 and other properties of the phosphorescent state.  Selectivity by the heavy atoa

 effect is especially good in DM which normally is not highly  luminescent.  As a major

 system for study, we intend to use Alllun cepa for which cytologifcal data of chromo-

 socal aberrations of root cells caused by mercurial treatment  exists.
 LEAVE BLANK                                                             — — — ^.^— — — —

Task:   ERR-4.9
Agency:  NIEHS
Funding;   $44,000 -  76
Project Officer:   Dr. Robert L. Dixon
Est. Completion Date: 1977
 PHS038                              ~   PAGE 2~
 R».3-70
                                      244

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               U.S. ENVIRO'IMLHTAL PK01ECTIOI AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                            (•'firm Aftprnt-rj
                                                                          OHO So.-'iiS-RnM
                                                                 SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                   EPA-IAG-D6-E772-BCR
Effects of energy-related pollutants on behavior
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

Clifford L.  Mitchell,  Pharmacologist, Environmental Toxicology Branch
NAME AND ADDRESS OF APPLICANT INSTITUTION
tfat1 1 Institute of Environmental Health Sciences,  P. O.  Box 12233,  Res  Tri  Park, N C
 7709
SUMMARY Of PROPOSfc'O Y.OPK - (1) Obji-vtlwt, (2) Appre-acli. (3) Cutrcnt Plun* and/Of ProgT*»» i2QO word* or !«»•- Omit confidcr.ii*: dat*).
   tn the SmitSianlnn Science Inforirmtion Exrhnnqc, aummariei of work in projrr**« »r* exchanged with government and privalv afe-nctt* »yp-
pufllne r*«*a«reh and arc fofward*d to invettigateri who f*q-j*«t *ueh informal ion. Your »«nwn»fy IB lo b* ux«d for thece pu*(vo»*».

   We  are proposing to study the effects of energy-related pollutants on male and female
lehavior in the rat.  An important function of this project will be to focus attention on a
elatively  neglected  area  of  health effects of the energy crisis, namely, the toxicity of
sollutants for the nervous system and the resultant changes in behavior patterns.   A major
tart  of this project will be to look at a spectrum of behavioral and neurotoxicity tests for
heir reliability and validity in detecting low level,  chronic effects of known and unknown
leurotoxins.  Special attention will be paid to heavy metals and interactions of these with
lydrocarbons, especially in the developing animal where the behavioral and neurologic
latterns are being laid down and thus represent  systems likely to be most susceptible to
 ffects.
 lOt'NTIFY PF.OKtSSIONAL SCHOOL INVOLVED f.«e./if.,/.
 """"'• •"'•'
SIGNATURE OF PRINCIPAL INVESTIGATOR
  Clifford  L.  Mitchell
                                                                               10/20/76
    SUPPORT MCTHOO /C/n-cJc one!
 VU^COL.GAT.OTV.Y.

 $150, 000      1 76
                                        FOR OFFICE USE OliLYl_
                                  ERR-4  10
       PROJECT OFFICER
       Dr. Robert L.  Dixon
       RESPONSIBLE ORGANIZATION

      I  NIEHS
                                                           "ARTINGOATE
                                    {.JT.M.TK, COM-U.T.
                                      1977
 £PA r>,m S760-I (7-72)     REPLACES P«5 FORM 'to AND SI-SIE 76A WHICH MAY NOT 8C USED.
                                           245

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               U.S. ENVIRONMENTAL PKO1 ECTICN AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                       OVR.V* MS-KrtOM
                                                               PROJECT NO. (O» noc iue> cf>t» «M»cr
                                                               SSI6
     PREPARED rOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                          EPA-IAG-D6-E772-BCS
3 F?°JECT
               Chemical and Environmental Mutagen Studies Utilizing the Tradescantia
GWE NAMES. OEPAHTMLNTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OB PROJECT DIRECTOR] AMD ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.

Contractor1.s Project Director  Arnold H.  Sparrow, Ph.D.,  Brookhaven Nat1 I Lab.;
Project Officer {NIEHS):  Frederick J. de Serres,  Ph.  D.,  Chief,  Environmental Mutagenesis
Branch
MAKE AND ADDRESS OF APPLICANT INSTITUTION

Nat11 Institute of Environmental Health Scienc.es,  P.  O. Box 12233,  Res. Tri. Park, N.C.
27709
SUMMARY OF PROPOSED WORK .  (i) objwtivi-s. (2> Af>pro»eli. (3) Current Ptjn* and/or Proc;t» (200 uror4» or !••». Ontil confidcntlM! dam).
   [n the Smithyor.inn Science Information Eftrhnnce. lurftBMirte* of work in progre«» are exchanged with government and prix-«tr •crncl«« »up«
purling recearch and are forvarded to inve»tteater» who request «uch information. Your lumraary [• to b« med for thoce purpOftoe.

    Refinements in Chemical mutagen exposure techniques were made to establish 1, 3-
dibromoethanol (DBE) as the mutagen standard in the.se studies rather than ethylmethane
sulfenate (EMS) and this work, has continued using tritium  labeled DBL.  Plant breeding
and new clone selection has also been continued to obtain more sensitive  clones which
might provide better indicators  of weak mutagens and  chronic levels of exposure.  New
clones with a wider-range of spontaneous mutation rates  at each of three loci are being
used along with existing mutable clones to develop methods for studying repair.

    Additional exposures of longer duration have been made with DBE; doae response
curves from exposures of concentrations of 2 to 100 ppm for 2  to 144 hours  exposure  show
that straight line relationships  on a log-log plot with  slopes of about 2. Furthermore, the
concept of  time X concentration plotted against mutation  frequency also shows a straight
line relationship on a log-log plot for all exposures, from 2 hours to 144 hours.
tl'-tHi,l. ,-tc.l
        Pr,Or£SS"ONAC SCHOOL INVOLVED Ofei/ic.J
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                      FOB OFFICE USEOHLY
   SUPPORT METHOD fCji,-cfc or»c.'    TASK NO.

                             ERR-5.1
'UHOS OBLIGATED  F.Y.
 $180,000     76
                                          PROJECT OFFICER
                                            Dr.  Fred de Serres
                                          RESPONSIBLE ORGANIZATION

                                            NIEHS
                 NO. 0»' FUTJRC YEARS TENTATIVELY
                 ASSUMED BEl-GNO CURRENT F.Y.
                                                   STARTING OATE
r.STIMATEO COMPLETION
OATE
EPA Form S760-I (7-72)    HCPLACES PH5 FORM 1C6 AND SI-SIE 7GA WHICH MAY NOT BE USED.
                                          246

-------
             U.S. ENVIRONMENTAL PROTECTION AGENCY
              NOTICE OF RESEARCH PROJECT
    PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                Form Apftrovtd
                                                              OMB Ko. J5S.ROOS;
                                         PROJECT NO. (Do not use this space)

                                         SSIE
                                         EPA	
                                        4PA-IAG-D6-E772-BCS
Effects  of Energy
                PolliitanttB
                                        ADStraccmg  or L,iceracure on nucagenie
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
 Con tractor's Project Director:  John S. Nassau,  Oak Ridge  National
   Laboratory, Oak Ridge,  Tennessee
 Project  Officer  (NIEHS):   Dr.  H. V,  Mailing, Head, Biochemical Genetics
   Section. Environmental  Mutagenesis Branch
NAME AND ADDRESS OF APPLICANT INSTITUTION
 National Institute of Environmental Health Sciences, P. 0.  Box 12233,
   Res. Trl. Park,  North Caroline, 27709
SUMMARY OF PROPOSED WORK- (1) Objectives, (2) Approach, (3) Current Plan* and/or Progress (200 word! or less. Omit confidential dam).
  In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting: research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.
 The tasks the Environmental Mutagen  Information Center will carry out are
 to compile the  past and  present  literature  on mutagenesis testing of
 energy related  pollutants.   This information  will then be processed  into
 EMIC's data bank noting  bibliographic details,  and keywording of chemicals
 organisms, and  systems studied.

 Energy Information Files Now Available at EM 1C

 Petroleum Refinery Stream Effluents  - select  chemicals from effluents re-
 sulting  from refinery streams were searched for potential mutagenic
 activity (and "select" toxlcity).

 Toxlclty of Coal Llqutfactlon Products - limited .search  of general publi-
 cations  in "EMIC" phale  oil,  oil shale, coal  conversion,  and energy-
 related  filer for toxicologies1  information.

 Coal conversion files are being  maintained  and  pertinent references  are
 being  selected  and added for possible interest  to our funding agencies.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED fMedl«l.
                                    SIGNATURE OF PRINCIPAL INVESTIGATOR
                                  FOR OFFICE USE ONLY
   SUPPORT METHOD (Check <
   AGENCY STAFF tintramufal)
   RESEARCH GRANT
                           ERR-5.3
                            PROJECT OFFICER
                            Dr.  Fred de Serres
                                         RESPONSIBLE ORGANIZATION
                                          NIEHS
FUNDS OBLIGATED
$45,000
76'
                   NO. OF FUTURE YEARS TENTATIVELY
                   ASSURED BEYOND CURRENT F.Y.
                                                 STARTING DATE
                                                                   1977
EPA Form 5760-1 (7-72)    REPLACES PUS FORM 166 »NO Sl-SIE 76* WHICH MAY NOT BE USED.
                                     247

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             U.S. ENVIRONMLNTAL PROTECTION AGENCY
              NOTICE OF RESEARCH PROJECT
                                                                t-(trm A
                                                              o.nn .\a.
                                                       PROJECT NO. (Do not i

                                                       SSIE
    PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                       ¥PA-IAG-D6-E772-BCS
TITLE OF PROJECT Elec tr ophore s is of Mouse  Tissue:   Testing- of Offspring After

GIVE NAN-Ssi DEPARTMENTS!*"o OFFICIAL TITLESW PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Contractor'?  Project Director:  Dr.  F.M. Johnson,  Research Triangle
    Institute,  Research  Triangle Park,  North Carolina
 Project Officer (NIEHS):   Dr. L. R.  Valcovic, Acting Assistant Chief,
    Environmental Mutagenesis Branch
NAME AND ADDRESS OF APPLICANT INSTITUTION
 National Institute of Environmental Health Sciences, P.  0.  Box  12233,
   Res.  Tri. Part,  North  Carolina  27709
SUMMARY OF PROPOSED WORK- (1) Objective, (2) Approach. (3) Cm-rent PUms and/or Progress (.200 words or !«•». Omit confident!*: da in).
  In the Smithsonian Science laf of mat Ion Exchange, aurnrnaries at work in provost are exchanged wi:h government and private amende* »up-
l>6rting rvaearch «id arc forwarded to investigator* who request «uch information. Your Bummary I» to be used for thete purpose*.
       The sturfy of specific  enzyme mutations using electrophoresis  has the
 capability of  detecting mutations that result in either  a non-functional
 protein or a functional protein with altered  electrical  charge.  Our
 objective  is to develop a single mammalian  test system that will detect
 both electrophoretic mobility (EPM)  and inactive enzyme  (IAE) mutations
 in the same  loci.   Two inbred mouse  strains which differ with respect to
 nine enzyme  loci have been  selected  for this  system.   Adult males  of each
 strain to produce F3 hybrid offspring.  Tissue  samples are obtained
 surgically and electrophoresis is conducted on  crude homogenates.   While
 sampling is not yet completed, preliminary  data indicates that  the system
 is at least as sensitive  in detecting IAE mutations  as is the morphologies
 specific locus system.  Several mutants have  been obtained and  currently
 studies are  underway to determine the biochemical nature of the induced
 mutation?.
Ut-'NTIFY PROFESSIONAL SCHOOL INVOLVED (\leiltcitl
 -    -
                                    SIGNATURE OF PRINCIPAL INVESTIGATOR
   SUPPORT METHOD fCJ,,-ct o,,,.)
' UND1 OBLIGATED

$140,000
76
                                 FOR OFFICE USE ONLY
                         TASK NO.

                           ERR-5.6
                            PROJECT OFFICER
                             Dr.  Fred de  Serres
                            RESPONSIBLE ORGANIZATION
      NO. OF FUTuPC YEARS TENTATIVELY
      ASSUMED BEYOND CURRENT F.Y.
                                         JilEHS.
                                    STARTING DATE
I
LSTIMATEO COMPLETION
DATE
                                                                       1977
EPA Torrn 5740-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                     248

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             U.S. ENVIRONMENTAL PROTECTION AGENCY
              NOTICE OF RESEARCH PROJECT
                                                              Form Affni-rJ
                                                             ovn .\o. Ms-«nos
                                       PROJECT NO.. (Do not ti.iv thin space)

                                       SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                      EPA-IAG-D6-E772-BCS
Monitoring Mutagens (Clastogens) With Mammalian C
OIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS ANO ALL OTHER
 ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 .C. Hsu,  Biologist and Professor  of Biology, Dept.  of Biology
Sen Pathai, Assistant Biologist, Dept. of Biology
Frances E. Arrighi, Associate Biologist and Associate Professor  Biology,
  Dept. of Biology
NAME ANO ADDRESS OF APPLICANT INSTITUTION
The University of  Texas System Cancer Center M.  D., Anderson Hospital  &
Tumor  Institute, 6723  Bertner Avenue, Houston, Texas  77025
 SUMMARY OF PROPOSED WORK - (]) Objective*. (2) Approach. (3> Current Plans and/or Progreas i200 words or less. Osiil confidcntinl data).
   In Ihe Smithsonian Science Information Exchange, summitries of work in progress are exchanged with government and private agencies »up-
   ing research and are forwarded to investigator* who request such Information. Your summary i*- to be used for these purposes.
      There is an urgent need for devising & standardizing procedures  for
 nonitortne the effects  of environmental mutagens  on the genetic systems of
higher  animals.   For practical purposes,  these procedures should be rela-
tively  inexpensive,  not laborious,  easily quantitated,  and the test objects
should  be related to the genetic system of man and  other mammals.  Chromo-
somes of cells in culture fulfill  all these criteria  and should be one of
the most suitable testing materials.   Since most  mutagens induce chromosome
damage  (hence they are  also clastoeens).  chromosome damage should  serve as
a  conservative indicator of gene Damage.   However,  investigators in the
past used various test  objects (many  were poor materials)  and test systems
 [many haphazardly designed)  so  their data are incomplete and are not strict
ly comparable.   This project is  designed to systematically test several
cytologically advantageous materials  and to determine the most efficient.
economical and information-yielding protocol for  future screening  of  enviror
 nental  mutagens.   Our test materials  include, in  addition to diploid  human
Cibroblasts,  cells of the Chinese  hamster (for its  fast growth rate and goo'
chromosomes),  the Indian muntjac (for its very low  diploid number, 2n-6),
two species of the deer mice (differing drastically in the amount  of  consti-
tutive  heterochromatin  and repetitive DNA content),  the laboratory mouse,
 md several other species.  Test compounds will include well-known clastogerjs,
probable clastogens and untested chemicals.  The  drug experiments will con-
sist of continuous treatments (to  determine inhibition of mitosis, stickiness,
:hromosome orientation, breaks and subsequent aberrations),  aberrations in tie
 Cecoverv populations after ptlloo j-raatmimt-a  frAniionfy nf c< yfgr Mirnmat-id
 •MMMaMBrih^v—«-c m •_""•		__ .._« ,.. .- .   ,*.-~ii « TI i a r r\£ D CM M i" tO & I P^VESTIGA'
 •JtNTIFY PKOt- ESSlONAL SCHOOL IN VOL VED O
                                    SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                           (over
                                 FOR OFFICE USE ONLY
   SUPPORT METHOD .C Y STAFF (hilt.
      f AflCM GRAN T
 •UNO OOLlGATED

 $112,159
76
           TASK NO.

             ERR-5.7
PROJECT OFFICER
Dr. Fred  de  Serres
                                         RESPONSIBLE ORG4NI 2 ATION

                                         NIEHS
     NO. OF FUTURE YEARS TENTATIVELY
     ASSURED BEVONO CUHHENT F.Y.
                                                 STARTING DATE
                        f STIMATED COMPLETIO'-
                        DATE
                         1977
 EPA Fo™ 5740-1 (7-72)   REPLACES PHS TOHM 166 ANO SI-SIE 76A WHICH MAY NOT BE USED.
                                     249

-------
 MI KISS.1!! A!! SCIFKCS I'lrtftMUlK! t>:S!IA':C£
ftCJiCT CUftlEit (Do HOT 
-------
            t S«i*ne« Informs*
   lion* Excnong*i

   Not f«r pullic«tlon v publleellon
        U. S. Deportment of
HEALTH, EDUCATION, AND WELFARE
       PUBLIC HEALTH SERVICE

NOTICE OF RESEARCH PROJECT
                                                                   PROJECT NO. (00 NOT USE mi: SPAtt)
                                                                   EPA-1AG-D6-E772-BCT
 TITLE OF PROJECT
       .
 Species-To-Species  Carcinogenesis Extrapolation
  G.  M.  Williams, M.D,,  Principle Investigator
  il.  H.  V.'eiskirrjer,  M.D., Senior Scientist
  Hildagard Marquardt,  M.D., Scientist/Librarian
  Steven Ltellman,.  Ph.D., Head of Biostatistics Section
                                                              "«"<<"
                                                                                 "L OTHER
 NAME /.NO A&DRESS Oi- APPLICANT INSTITUTION

  African Health  Foundation    137C Ave-  of the fc
_______________________ ?Jev/..York, . fe>.' . Ypfk  1f^?   (Tc  Y.;:_pcr?cm:$ <.;t; Vi   1  -
 f'J.".«AHV C'F f-^Oi'-OSEP VORK -(2j" v/o.-Jj or hsi .-Omit Cunfio'enliol rfo.'o.)
   In Ida Sc.ior.ce Inrcrii-.OTion EKehcinge' surrnifrici of wor'i in pre^rssj o'C '
   fcio-s^itneos
               rs fn.warrfed to in r ;*!i3a!ors who r
                                             informdtion. Your sii
                                                           ilS pav^rnfr-cfiT anJ prtvn",- f^-oci
                                                           n-cfy is 10 be us«c! fcr th?s.< p.,Tpr-
 ThTr piajcr piirpo^^ of t!;is contract  ii;  to create a data mssKry  f»o;n p!.:bli.-!.f:.i st.usl'i'.s
 in the field c?'  c;rcinvvc;:ijsis ?.v;o  to  sjti'lijze this data sun^aiy to Invtstl^ate v:r'ic^
 &cp>.-c:ts of ttse cjucntification of species differences foilov/'in-ii  e;;poiiire •v.o specifier!
 Ccircir^ooanic agerita.  Special attention  will be given to issues such as atU:iiptinn to
 establish the most appropriate c'ose equivalency between species,  the depenihncy of
 activity on Rfit~boV!c p^th'-'^ys and  nsetafcblic activaticn/detoxificsticn fsc'tr^'S. and
Task:   ERR-6.3
Agency:   NIEHS
Funding:   $59,000 - 76
Project Officer:   Dr.  David G.  Hoel
      Completion Date:  1977
PROFESSIONAL SCHOOL ?m«drc
WHICH THIS PROJECT SHOULD



.-./, dtnicl, tie.) WITH
BE IDENTIFIED
DO
NOT
SIGNATURE OF
WRITE BELOW THIS
LINE-
PRINCIPAL
FOR OFFICE
IN
VESTIGATOR
DATE
USE ONLY
 SUPPORTING AGENCY
 KSTHCO OF r.i..;-porcT r
 D-&.r       nsrr-       JD^G^  __   Dj:rr   _D!
         V-T-r"7r7i^?" TTV   r:'ir-'-''r: 0~? F'JUIRE VaAM TCri fi.Tivr!.',' ASSURED 1~		
         IUA, ..u V.IM.H-	  j ;;%y v,,-_; tujjriiKT FISCAL Y£/E
                                                   c:;.."i J:./.;; ,i/.T6
                                               251

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                                  SECTiom
               DEPARTMENT '
                        " HEALTH. EDUCATION. AND WELFARE
                         dLIC HEALTH SERVICE
                     RESEARCH OBJECTIVES
                                                             16AVE BLANK
             PROJECT NUMtEH

             EPA-IAG-D6-E772-BCT
NAME AND ADDRESSCF APPLICANT ORGANIZATION
Department or Statistics
367 Rvans Hall
University of California
Berkeley, California  34720
NAME. SOCIAL StC'JFUTY NUMBER. OFFICIAL TITLE, AND DEPARTMENT OF ALL PROF ESSIONAU PERSONNEL ENOAOCO OH
PROJECT, BEGINNING WITH PRINCIPAL INVESTIGATOR
 J.  Neyman, 561-46-6637, Director,  Statistical Laboratory, Professor of
       Statistics
 L.  LeCam,  572-58-5796, Professor of Statistics
 E.  L. Scott, 559-58-4487, Professor of Statistics
 F.  N. David, 572-68-5929, Chairman,  Department  of Statistics, Professor
       of Statistics
 H.  Lewy,  220-22-0146, Professor Emeritus of Mathematics
TITLE OF PROJECT
 STATISTICAL  STUDIES  OF PROBLEMS OF HEALTH AN'D BIOLOGY'	
USE THIS SPACE TO ABSTRACT YO'JR PROPOSED RESEARCH. OUTLINE OBJECTIVES AND METHODS. UNDERSCORE THE KEYWORDS
(NOT TO EXCEED 10) IN YOUR ABSTRACT.


         It is intended to work on  the  development of statistical  and
    probabilistic subdisciplines  particularly important in the  studies
    of biology and health problems.   Whenever possible, such  studies
    will be conducted in conjunction  witli  substantive biological
    studies.   To facilitate  the  establishment of the relevant  contacts,
    seminar meetings with substantive speakers will be used,  once  a
    week during the academic  year and more frequently during  summer.
    Many problems contemplated for  the  immediate future are suggested
    by the current energy crisis.   The  broad, say, ultimate statistical
    problem connected with this crisis  can be stated as follows:
    given that in a locality  a new  energy  producing plant is  to be
    constructed, with a specified additional  environmental pollution,
    to estimate the consequent changes  in  the selected parameters  of
    public health.  It  is proposed  to study a number of subproblems of
    this "ultimate" problem.  These include:   (i) the use of  Markov
    chains to study "competing risks",   (ii)  methodology of treating
    factorial experiments,( i i i) co"nstruction of stochastic  noclels
    o?biological phenomena  like  carcinogencsis and jautagcncsis.Some
    relevant mathematical problems  will also  be studied.
 LEAVE BLANK
 Task:  ERR-6.12
 Agency:  NIEHS
 Funding:  $76,350
 Project Officer:  Dr.  David G.  Hoel
 Est.  Completion Date:  1977
  HiH 358 (FOOWEDLT PH3 355)
                             252

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                 DEPARTMENT OF HEALTH, EDUCATION, Ar;D rt
                           PUBLIC HEALTH CdRVICT

                         RESEARCH  OBJECTIVES
                                                                      ICAVE DLAVK
EPA-IAG-D6-E772-BCT
NAME AND ADOHESSOF APPLICANT ORGANIZATION

  State University of Sew York at Buffalo	
NAME, SOCIAL SECURITY NUV3cR. Off ICIAL TITLE. AND DEPARTMENT OF ALL PROFESSIONAL PERSONNEL ENGAGED O.'i
PROJECT, 8KGINNINO WITH PRINCIPAL INVESTIGATOR

  1.  C. P.  Yu,  540-46-8993,  Professor,  Department of Engineering Science, Aerospace
      Engineering and Xuclear Engineering.

  2.  D. B.  Taulbae,  363-36-5370, Associate Professor,  Department of Engineering
      Science, -Aerospace Engineering  and Nuclear  Engineering.

  3.  Two Research Assistants  (to be determined).

 TITLE OF PROJECT
               Respiratory Tract  Deposition of Inhaled  Aerosols
 USE THIS SPACE TO AtiTRACT YCUa piOFOSEO RESEARCH. OUTLINE 06j£CTIVtS AND METHODS. UNDERSCORE THE KEYViOTsCS
 (NOT TO EXCEED 101 IN YOUR ABSTRACT.

       Mathematical godels_ are to be  developed for  theoretical prediction of particle
  deposition and distribution along the  respiratory tract  systea.  Specifically, the
  following tasks are to be undertaken during the period of  requested support:

       1.  Develop a  mathematical model  for deposition  in  taan at nose-breathing.

       2.  Reco=3end  figifres  for  the  regional deposition in  the hiraan lung at nose and
           nouth-breathing under  various working  conditions.  Enphasis will be given to
          'fine particles which are difficult to  be removed  froa power plant emissions.

       3,  Develop a  cathematical model  for deposition  in  smokers and patients with
           chronic obstructive pulmonary disease.

       4.  Develop a Eathematical model  for deposition  In  experimental animals.

  Xhe basic nethod to be used is  the  one previously developed by the principal investi-
  gator and his faculty associate.
 ItAVE BLANK
 Task:  ERR-6.11
 Agency:   NIEHS
 Punrllngi  $48,000  - 76         s
 Project  Officer:   Dr.  DtvlH .G. Hoel
 Est.  Completion Date:  1977 s
  KIN J'-S  JfiSKIBl? FKS J»!j
                                 253

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                 06PAHTMENT OF US AOTH. EDUCATION. MHO WELFARE
                           PUIILIG HEALTH itIWICt

                         RESEARCH OBJECTIVES
NAME AND ADDRESS OF APPLICANT ORGANISATION
                                                                        ICAVP BLANK
                                                               pnojcct
                                                               EM -IAG-D6-E772-BCT
University of Maryland - Baltimore County,  Dlvls
5401 Milkens Avenue, Cavonnvlllc, Naryland  21228
                                             Division of Mathematics find Fhysicg
NAME. SOCIAL SECURITY NUMGCH. OFFICIAL TITLE, AND DEPARTMENT Of ALL PROFESSIONAL PERSONNEL CNUAGtO ON™
PROJECT, BEGINNING WITH PRINCIPAL INVESTIGATOR
Allan H.
                   278-36-6673, Associate Professor, Department of Mathematics (P.I.)
TITLE Or PROJECT
 Conpartmental Models For Body Burden Of Pollutants
USE THIS SPACE TO ABSTRACT YOUR PHOPOSfcD RESEARCH. OUTLINE OBJECTIVES AND METHODS. UNDERSCORE THS KEY WOBSW
(NOTTO EXCEED 10) IN YOUR ABSTRACT.

      It Is often possible to model the body burden of pollutants as a mixed exponential
moving average of the external pollutant dosage.  This model fails:  (a) when the pollu-
tant occupies a significant fraction of a system e.g. carbon monoxide.  (b) when an
appreciable fraction of pollutant is retained in long-lived components e.g. bone-seekers
such as lead.  A sami-Markov model for physiological kinetics generalizes this model.
By representin'g body burden as a stochastic integral of external dosage, it is often
possible to estimate the frequency, duration, and parameters of other integral
exceodance measures for body burden, thus to estimate the effects of environmental
quality standards on body burden variation.  Physiological kinetic models for carbcn
monoxide, for the lead-calcium system, and for cadmium-zinc, will be estimated using
non-linear regression techniques for experiments (as reported in the literature) on
uptake and elimination in constant evironments.  Stochastic models will be developed
for external dosage of CO and lead, and the parameters of the exceedance measures of
body burden estimated.  In this way it may prove possible to establish a better
rationale for environmental standards setting.
 Task:   ERR-6.14
 Agency:  NIEHS
 Funding:   $21,000-76
 Project .Officer:   Dr.  David G.  Hoel
 Est.  Completion Date: 1977

 LEAVE BLANK
  KIM 3311 (rcrmtnt.Y CHS
  »"• 1/73
                                 254

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   Pi«p«.d for fh« Sciwic. Inloraio*
   tl«n
      fir rufclicotJM or publication
                                         U. S. Department of
                                HEALTH, EDUCATION, AND WELFARE
                                        PUBLIC HEALTH SERVICE

                                NOTICE OF RESEARCH PROJECT
                                                                      PROJECT NO. (DO HOT USE THIS SPACE)
                                                                       EPA -IAG-D6-E772-BCT
    Extrapolation of Polychlorinated Biphenyl  Deposition
 JIVE NAMES, DEPARTMENTS, AMD OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
    T.L^El'ing, pNh.LD.^GACo-i?eaa1,Ef'fia'ruacokinetic Section, Pharmacology Branch
    M.M. Anderson, Ph.  D., Co-Head, Pharaacokinetic Section, Environmental Biometry Branch
    H.U. Matthews, Ph.  D,, Phamacekinetic  Section, Pharmacology  Brandt
    D. Tuay,  !'h. D..  Phaivacoklnetlx; Section, Dv/i roni.rcntal uionetry Branch
 NAME AND APDRESS OF APPLICANT INSTITUTION

 fiational  Institute  of EnvlrosiRental llaalth Sciences,  P. 0. Box  12233, Ras.  Tri. Park, H.C. 2.77'.
"JUMKARY Cl! PKCiP
   In the Science
                            fl* sufflm'->r 'jo;'i-
 a^d E!aftk2"-s*  Ths  date cb^ln^ri froia  thasa f!f?;t'jsit:ior\ studies  frill ba used is; tfi^
 construct;ca of  p!iavi,acckvr.^tic wocfels  vor- x:iis purpose of spacius oxtrapolrcioii.  The
 contract for tiis initial disposition  studios vnll  ba awarded  approximately  lioveafcer,  .b/6.
 PROFESSIONAL. SCHOOL (miJIcol, cTe/irol, tie,)
 WHICH THIS PROJECT SHOULD 85 IDct'TIFIED
                                            SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                                         DATE
                             00 MOT WRITE BELOW THIS LINE -FOR OFFICE USE ONLY
 SUPPORTING AGENCY
                  HTEHS/Project Officer:   Dr.  David G.  Hoel_
 ii.:TKOr> or suproRT jci^ct °»c
     DA».r.er S.olf       f"~| NcsolloteJ
     	1 Conlrni
"Tlj«pToou'cA"cD"cITsfis";JrTvrTKuMa•:a o:
                            I *iUYONl> r
  $140,000  -  76


 |j|«-1?«« (FtftMERi.Y PMS-lii)
 REV. «./2
                                          DSpceiol           I   I R.scorch
                                          Proicel Oion'       '	' Cranl
Olhe.
(Specif/)
                                                                      ['•Efil'IrliMt ii.M h    ESV|." '.T*::
                                                                                      co..i;'i;.ii
                                                                                       1977
                                               255

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             u.s. ENVIRONMENTAL PROTECTION AGENCY
              NOTICE OF RESEARCH PROJECT
                                                              O«B \» DS-ROOS1
                                                      PROJECT NO. (Do not at* till* tpfeti

                                                      ssie
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                             EPA-IAG-D6-E772-BCU
TITLE OF PROJECT
Effects of Pollutants Upon Alveolar Macrophaees
&IVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
John  R.  Rowlands,  Ph.D. - Director, Environmental Science
Emily M.  Cause   M.S.  - Sr. Res.  Scientist,  Environmental Science
Martin  L.  Mcltz, Ph.  D. - Sr. Res. Scientist,  Environmental Science
Bruce McCullough,  Ph.  D  - Staff Pathologist,  Environmental Science	
NAME AND AUOHESS OF APPLICANT INSTITUTION
Southwest Foundation for Research & Education
P. 0. Box 23147  (8848  West Commerce Street)
San Antonio. Texas  78284
SUMMARY OF PROPOSED WORK -  (1) Ob;i'-.-tiv.-«, (2) Approach, (3) Current plan* •nd/or Progress (200 words or lest. Onit confidential data).
  In lhe Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private a(*ncl«s »s»p-
pocting research amd are forwarded to investigators who request such Information. Your summary is to be used C*f these purposes.

     A  research study has been  designed to:  1)  detect directly, by  means of
spin  label measurements, membrane .lesions  produced  from in vivo exposure of
alveolar macroohaees to pollutant atmospheres - both  oxidant and  reducing; 2
obtain  experimental  evidence  that these lesions are, or  are not, associated
with activity of membrane-bound  enzymes and with phagocytic and respiratory
capacity of the alveolar macrophage; 3) relate dose-dependence of  observed
induced  membrane lesions with response of  intracellular  systems—specificall
lysosomal enzymes, a  cytoplasmic  enzyme, cAMP, and RNA/DNA synthesis{4)
assess the effects of the same  in vivo exposures upon  selected lung systems
which will either exert a pharmacological effect upon  the macrophage membrane
(such as cAMP), or provide an altered substrate for phagocytosis by the
alveolar macrophage  (i.e., the  lung surfactant); and 5)  evaluate the effects
of the metabolic and  functional prate of the alveolar  macrophage itself
(i.e., actively phagocytic or resting) upon production of lesions,  impair-
nent of  function, and particularly upon surrounding lung tissue.
       PROFESSIONAL SCHOOL INVOLVED (Medic.,1,
                                    SIGNATURE OF PRINCIPAL INVESTIGATOR
                                 FOR OFFICE USE DULY
   SUPPORT METHOD ICht-ck one)    TASK NO.


                             ERR-7.6
STAFF fltitramir;il)
    T5f ARCH CR AN T
 f UNCO OBLIGATED I F.Y.

 $91,566     [76
PROJECT OFFICER
Dr. Larry G. Hart
                                RESPONSIBLE ORGANIZATION
          NO. O^ Fu'LJt-'P YEARS TEMT*TtVEt_r
          ASSUMED OEfONO CURRENT F.Y.
                                         GIEHS_
                                        STARTING DATE
                         LSTlMATeD COMPLETION
                         DATE
                                                            1977
 EPA form 5760-1 (7-72)    REPLACES PHS FORM I6S AND SI-SlC 76A WHICH MAY NOT BE USED.
                                      256

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              	SECTION 1	
               DEPARTMENT OF HEALTH. EOUCATIO'i. AMD WELFARE
                       PUBLIC HEALTH 56RVICE

                      RESEARCH OBJECTIVES
       1EAVE BtANK
EPA-IAG-D6-E772-BCU
NAVE AND ADDRESS OF APPLICANT ORGANIZATION                                  	'	
 Duke University Medical  Center,' Durban,  N.C.  27709


NAVE. SOCtAL. BECuaiTY NL'VSER. OFFICIAL TITLE. AND DEPARTMENT CF ALL PROFESSIONAL PERSONNEL ENSAGED ON
PROJECT. EEC.'.SING WITH PRINCIPAL INVESTIGATOR
 Daniel = . l.'enze!,  5o9-*c-329of  Assoc.  Prof. Fnarracelogy & Medicine,
   Heac,  Div.  of FharnacoIogy,  Deot.  of Fhysiolccy & Pharmacology
 huco C.  Jaureoui,  299-*--7680,  Ast.  Prof, of Pathology, Dept. of
   Pathology
 Can  Vit  £ or Lipid Alter N02  or 0-, Toxicity In Lung?
USE THIS SPACE TO ABSTRACT YOUR PROPOSED RESEARCH. OUTLINE OBJECTIVES ASO METHODS. UNDERSCORE THE KEY WORDS
 vzcne  I-.c! ni trcasn di oxide may exert their toxic effects-by oerox itiati on
 of ins i.nsaturated fatty acids of the JJJ.IQ and other tissues.   To  test
 this hyocthesis, mice will be fed chemically defined diets known  to
 produce  lung Molds having differing decrees of susceptibfIity  to  lipid
 oeroxiiation.  Diets v/i I I  be  deficient or sufficient in  vitanln £ or
 contain    -tocopheryl qulnone or oher.ol.ie anticxiba-ts.  Aninals  v;i I I
 be  excssed to ozone and nitrogen dioxide anc! the dsse-response  relation-
 "ship between the toxi^ity  of'these air collutsnts and the peroxidiz-
 ability  cf the  lung  lipids will be determined,  .he protective  effect
 of  vits.-.in E and other  ohenolic antioxidants will be determined.   The
 effects  of afr pollutant exposure will also be neasured  by changes in
 growth end  in lung  lipid composition and enzyne content.  Potential
 defense  mechanisms  of peroxidases will be investigated in both  lung
 and  liver.  The toxi-c effects of ozone and nitrogen dioxide will  be
 conpared with putative  chemical intermediaries of toxicity.   These
 studies  are desicned to test the free  radical theory of  action  of
  these  air pollutants, and  to determine the dietary  levels of  anti-
 oxidants necessary  to prevent  lung damage at current concentrations  of
  air pollution.
 LEAVE BLANK
 'Task:  ERR-7.7
 FiitHlng:   $61,000-76
 Project Officer:   Dr. Larry G. Hart
 Agency:  NIEHS
 Est. Completion Date:  1977
                                257

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                	S5CTIOM 1
                 DEPARTMENT OF Hi ALTH. EDUCATION, AND WELFARE
                           PUBLIC HEALTH SERVICE

                        RESEARCH OBJECTIVES
        LEAVE BLANK
PROJECT NLVSSR
                                                                EBA-IAG-D6-E772-BCU
NAVE AND ADDRESS OF A?F:.ICAN7 ORGANIZATION
    College of Veterinary Medicine
    Michigan Stete University, East Lansing, HI
NAM=. SOCIAL S5Cu=.ITY N^V==R. OFFICIAL TITLE. AND DEPARTMENT OF ALL PROFESSIONAL PERSONNEL ENGAGED ON
PROJECT. 53G1\NI\S WITH PRINCIPAL INVESTIGATOR

   Kin. J.C.S.
   5*7-62-70112
   Associate Professor of Pathology
TITLE OF PROJECT
    Vi;g-.in A Eff»=t on Luno Cell Cvele Kinetics After NO-»
ISi TH:S S?AC5 70 ASSTSAC7 YOUR PROPOSED RESEARCH. OUTLINE OBJECTIVES AND METHODS. UNDERSCORE THE KEY WORDS
(NOT TO iXCEEO 101 IS YOU3 A9STR ACT.


    Epideniolcgical as well as experimental evidence suggests that the development of
    lung cancer is a result of complex interaction of a number of exo-and endogenous
    factors,  besides the carcinogenic insult, environmental factors modifying the
    target orcans, tha host factors such as genetic susceptibility, aging, nutrition
    and other host factors may be of paramount importance.

    V'tariin A Is known to bs essential on epithelial cellular differentiation and a
    deficiency of  it causes squamous metaplasia,  nitrogen dioxide not only produces
    basal .cell hyperplasia in the respiratory tract but also prorates infection and
    the tunoricenesis of chemical carcinogens.  The presence of this component not
    only as an air pollutant but also in cigarette scoke emphasizes Its importance.

    The objective of this proposal  is to Investigate the influence of Vitamin A on
    the cell cycle kinetics of the hamster respiratory tract resulting from exposure
    to  lOppn of H02  for 5 hours.  The role of Vitamin A in the respiratory tract will
    be studied fay  both light and electron autoradioeraphy with particular emphasis on
    epithelial cell  differentiation and me.tap]asic changes.
LEAVE BLANK
 TB sk:  ERR-7.8
Agency:   NIEHS
 Project  Officer: Dr. Larry G.  Hart
 Funding:   $20,000  - 76
Est.  Completion  Date:  1977
PHS-393                                     PAGE 2
Hw.3.70
                                  258

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                  OEMRTA_«TOF HEALTH. bOUCA I ion. ANU nsu-Ani:
                            PUBLIC HEALTH SERVICE
t        -».^r»»c Ol/MVIV
IpnoffiCT fJUMsin

{EPA-IAG-D6-E772-
„	.BCU
NAME ANO ADDRESS OF APPLICANT ORGANIZATION                    "
                                           University of Vermont
                                           Burlington, Vermont  05401
KAM6. SOCIAL SECURITY NUM3S B. OFFICIAL TITLg. AND DSPAHTMSNT OF ALL PROFESSIONAL PER5OMKEL dfrgAOEO OIJ
     T. BEGINNING WITH PRINCIPAL INVESTIGATOR

       Hart, Beth A.
          Assistant Professor
          Department  of Biochemistry
Tirue Of PROJECT  ERR-?.9        —~~~	~~~	'	*—	
._.. . THE INTERACTION OF CADMIUM.. WITH THE PULMONARY ALVEOLAR MftCRQPHAGE. 	
USSrTHlS SPACE TO ABSTRACT YOUH PROPOSED RESEARCH. OUTLINE OBJECTIVES ANO METHODS. UNDERSCORE THIsKGV l''0'3r
WOT TO EXCEED 10) IN YOUFl ABSTRACT.
        The heavy metal caAaiim.  a known environmental_pollujt:|iit. has been implicated ac
 * causative agent in the development  of lung pathology.  It has been suggested that one
 of the sites of cadmium  toxicity is the oxidative metabolism of the pulmonary alveolar
 nacrophage.   At present, there is little known about the interaction of cadmium with
 the alveolar macrophage  under physiological conditions.  It is the purpose of the .pro-
 posed research, therefore, to study the jTajisjiSSXj, intraeellular cjistrihi^.rpTi, and.
 accumulation of cadmium  by the pulmonary Alveolar macTOplmge and to relate the amount
 of cadmium accumulated within the cells to alterations in physio logical function.  Tran
 port by macrophage monolayers will be quantitated by the use of Ifl9cadmium.   The intra
 cellular distribution of cadmium will be determined by measuring the radioactivity _.
 present in the sub-cellular fractions (i.e., soluble cytoplasmic fraction, mitochovidri
 microsomes, and membranes) obtained after cell homogenation end differential  centrifug
 tion.  Atteiitpts to identify a specific cadmium-binding protein  will be made  by using
 column chromatographic techniques.  Direct measurements of the cadmium content of macr
 phages will bs made with the use of an atomic absorption spsctrophotometer equipped wi
 a micro-atomizer.  Experiments will then bs conducted to determine how the rate of.
 cadmium transport is affected by pH,  divalent ions, thiol-containing agents,  protein.Cs
 and alveolar lining material, and to  determine whether cadmium accumulation can occur
 during the phagocytosis  of bacteria and/or kaolin.  Hacrophages that have accumulated
 known amounts of cadmium under different environmental conditions will also bs'monitor
 i?or phagocytic activity, release of lyjjosomal enzymes, endogenous respiration. and
 ATPase activity.  Comparative studies with macrophages from various animal sources az-e
 planned.  It is hoped that the results o£ the proposed study will  contribute  to our
 understanding of the role cadmium plays in the development of lung pathology  in roan.


LEAVE BLANK

Task:  ERR-7.9
Funding:   $37,617
Agency:   NIEHS
Project Officer:  Dr. Larry G.  Hart
 Eft. Completion Date:  1977
  »IH 339 (FOi>»6tlLt CHS 353)
  ft... 1/73
                                       259

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NOT FOR
PUBLICATION
OR
PUBLICATION
REFERENCE
DEPARTMENT OF HEALTH, EDUCATION. AMD WELFARE
PUBLIC HEALTH SERVICE
RESEARCH OBJECTIVES
LEAVE BLANK
PROJECT NUMBER
EPA -IAG-D6-E772-BCU
NAME AND ADDRESS OF APPLICANT ORGANIZATION

University of  California, Davis, California

NAME, SOCIAL SECURITY NUMUfc R. OTFiaAL TITLE. AND DEPARTMENT OF ALL PROFESSIONAL PERSONNEL ENGAGED ON
PROJECT. BEGINNING WITH PRINCIPAL INVESTIGATOR

Sec attached list.

                              U.
TITLE OF PROJECT
Pulmonary Effects of Environmental Oxidant Pollutants
USE THIS SPACE TO ABSTRACT YOUR PROPOSED RESEARCH. OUTLINE OBJECTIVES AND METHODS. UNDERSCORE THE KEY WORDS
(NOT TO EXCEED 10) IN YOUR ABSTRACT.
     Rats  and monkeys will be chronically exposed to oxidanl air pollutants, primarily
ozone, at  concentrations approximating high ambient levels (0.2 - O.S ppra).  A
mul^'disciplinary group will make integrated biochemical, microbiological, physiological
and.morphological evaluations of effects.   The findings will have relevance to the
specific problem of air pollution and to a general understanding of pulmonary patho-
biology.

     By plotting the relative levels of sensitivity of the various parameters studied and
the effects observed, a basis will be provided for making predictions of possible long-
term consequences of photochemical smog on man.  Comparison of effects in rats and
monl;eys should provide for more confident extrapolation to man and hence enable the
setting of rational air quality criteria.

     A primary goal is to test critical hypotheses concerning biochemical, immunological
and cellular mechanisms responsible for the deleterious effects of the pollutants.
Major pathogenetic and modifying factors of interest are: the role of lipid peroxidation
in  initiating damage; the induction of antioxidant defense mechanisms by continued ex-
posure and the general phenomenon of adaptation; the sites of impairment in pulmonary
alveolar macropiiages and components of the immune system in the lung; the sequence and
nature of  lesions resulting in the development of chronic obstructive lung disease
(bronchitis/emphysema) and interstitial fibrosis.

     An additional goal is to explore further the potential prophylactic value for
human populations of dietary antioxidants such as vitamin E.

LEAVE BLANK

TASK:   7.10
Agency:  NIEHS
Project Officer:   Dr.  Larry G.  Hart
Funding:   $163,015 -  76
 Est.  Completion ,Date:  1977
I'HS 308                                     PAGE 2
Rw. 3-70
                                        260

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NA
DEPARTMENT OF HEALTH, EDUCATION. AND WELFARE
PUBLIC HiALTH SERVICE
RESEARCH OBJECTIVES
LEAVE BLA.'IK
EPA -IAG-D6-E772 -BCU
V.r AND ADDRESS OF APPLICANT ORGANIZATION ' ' 	
The University of Kansas
Lawrence , Kansas 66045
PROJECT. BEGINNING WITH PRINCIPAL INVESTIGATOR
         Duane G. Ifenzel    391-16-5213
         Program Director
         Pharmacology and Toxicology

         Carlton K.  Eticksoa   335-36-571/t
         Fiofessor  of Pharmacology  and Toxicology
         Pharmacology and Toxicology
                                                         Howard  ::ytting    528-S4-70S6
                                                         Asst. Pi.-ofp.saoj: oi  i'hariiiaceutJc^X
                                                                                   Cheraistry
                                                         Pharaaceutical Chemistry
TITLC Or ?riCJ.:CT I-.KK- /. iT
     Env.'.ronia'iiita'L  C-r.iln"•::?:  Tor:; eulogy 1'rograrv
Ls.E l:;;:: ;;:'•••
        XCj.i.C1 -.01 I?! YOU' A>;'.:Tf:ACT.
              This:  :U> ;_• rcm.'.OHt. for  an Fty/lron.-"..-.^-1'.'!. Cellular TcoT'.c.o.1. :• r.v v.----. /-;;t? ;:':o  ai.'. .•/ o': t'i
        t'o:-.iuo'c;^y  oi fv^vlrorii:!'?^c.:.:l  '"oijjc.-T.i.•• ,it fhe. c.r":"'.l;'-iar  .lr;-/e'! .   'j'/ic  C'n^ir.yi
        ir  to b.2 on -'-.i i;.r-:surc... ut o.f  a v-T-.'.p.ty of toxicant-inclucad altev.-.; Ions
        of  cultured or isolated cells as early indices of injury.  The thrusl; of
        this appro?ch will be to establish qyantitativa ir.?t:hodglpf;les  that rfilace
        to  Kiec1 .^•.vJ.!..3r. oi: !:o::i'~ity.  Cell Kiodal.; ;>;.« 'x- :'r,u". n!-.':  1)loi><3  pl.r; a.let ~,
              'i'Su }• 'og".. n will b
                                                   coonl :.i.;-i
                                                                   of
        J>.!sv'  Tojo.i-.'.l.'ij'.y is intc.j;rs<:e.d with tr.c Dcpa tni:;it.r. of  >Ied?.r:inal  Chemistry
        f.ii'l  Fiiai-raacoutj.eal Chemistry in the School oj; Pi Arir.acy,  and shave.-; thf; use
        oj: major equipment with the Cheittf.stry DeparCr.eni-. and  others,  the. rfcso-.:rco«:
        of these other departments are  also available to solve problems related to
        the  research program as set forth and to  graduate student education in
        Cellular Toxicology.
LEAVE BLANK
   TASK:   ERR-7.ll
   Agency :   NIEHS
   Funding:   $54.826
   Project Officer:   Dr.  Larry G.  Hart
   Est. Completion Date:  1977
                                              261

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                        OMB No. 1H-ROOS1
                                                               PROJECT NO. (Do rat «•• IMa ap«c*>
                                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                               EPA-IAG-D6-E773 - 78 BCX
TITLE OF PROJECT
 Assessment of Energy Occupational  Safety and Health Problems
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.

 Project Directors:   William L. Wagner, Chief,  Environmental  Investigations Branch
   and  Donald F. Knowles, Jr., Industrial Hygiene Engineer
 Phone:  (304) 599-7421
NAME AND ADDRESS OF APPLICANT INSTITUTION
 National Institute  for Occupational Safety and  Health, Appalachian Laboratory for Oc-
 cupational Safety and Health, 944 Chestnut Ridge Road, Morgantown, W. Va.   26505
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach. <3) Currant Plans and/or Prepaoa (200 word* or lass.  Omit coofMantlal data).
   In the Smithsonian Science Information Exchange, suttunarlea of work In pragma ara exchanged with fovanuMM and private acaoelaa sup-
porting research B*K| are forwarded to Investigators who request such Information. Yonr •uaaaarjr !• to ba naed for thoaa purpooea.

 The Appalachian laboratory for Occupational Safety  and Health is responsible for
 developing and maintaining a program designed to  identify  occupational health problems
 associated with the extraction,  processing, utilization, and  conservation of energy
 resources.  This  project is to provide technical  support necessary to Identify and
 define  future NIOSH project areas  related  to energy.   There will be interaction with
 other NIOSH scientists and scientists in other  federal agencies and other institutions
 associated with energy production.   Limited exploratory field investigations will  be
 conducted to evaluate current and  proposed processes, potential worker exposures,  and
 availability of records and study  populations.  The principle work will  be done by
 task order contract.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED r»feifl«il.
 (/1-I1M/, Ctf.)

            None
                                         SIGNATURE OF PRINCIPAL INVBST1OATOR
                                                                              Oct.  29. 1976
                                       FOR OFFICE USE ONLY
    SUPPORT METHOD (Cfli-i-h an,')
Funds Estimat^*CY-
  240K76
                                  1  -CX
                                                PROJECT OFFICER
                                                  John P
NO. OF FUTURE YEARS TENTATIVELY '
ASSURED BEYOND CURRENT F.Y.
                                   STARTING DATE
                                                        June 1976
yFunds approximate not for citation 'D 5I~SIE 76* "H|CH "AY NOT BE USED.
                                              262

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
     OF PROJECT1      	—	
Mortality. Morbidity and Industrial  Hygiene Study of Oil Shale Workers
                                                                         Form Approved
                                                                       OMB NO. ns-tiooai
                                                              PROJECT HO. (Do not un Wile epecej
                                                              ssie
                                                                BPA-IAG-D6-E773 ~ 78 BCX
 OIVE NAMES, DEPARTMENTS. AND OFFICIAL TITUES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
 PROFESSIONAL PERSONNEL EM6AGED IN THE PROJECT.

 Project Directors:  Robert Reger and Joe Costello, Epidemiologists,
   Phone (304) 599-7501;  William G. Jones, Industrial Hygienist,  Phone (304) 599-7421
 NAME ANO ADDRESS OP APPLICANT INSTITUTION
 National Institute  for Occupational  Safety and Health, Appalachian Laboratory for En-
 vironmental Safety  and Health, 944 Chestnut Ridge Road, Morgan'tovn, W. Va. 26505
SUMMARY OF PROPOSED »ORK _ (1) Objectives. (I) Approach. (3) Current Plan, and/or Progreu (3W ««ros or to... Omit confidential data).
  In the Smithsonian Science Information Euhange, sunnaartos of work in progress era eichenged with government and private aiencles sup-
porting research and are forwarded to investigators who request snch iflfermMien. Your sumanry is to be used for these purposes.

 This project is a study of 444 men who  have worked in pilot oil  ahale operations. The
 cohort will be  divided into three  smaller cohorts consisting of  (1.) 294 men from the
 U.S. Bureau of  Mines  and (2) 135 men of the Joint Venture  of the Colorado School  of
 Mines Research  Institute and COLONY  in  Anvil Points,Colorado,  and also (3) 15 men from
 the Union Oil Retort  facility  in Grand  Valley, Colorado.   A retrospective mortality
 study of approximately 60 men  will be done in house while  a cross-sectional morbidity
 examination to  evaluate several morbidity aspects that may be associated with oil shale
 occupations will  be done by contract^. | Mortality due to 21 specific causes of death
 will be determined after an extensive %d|||jp-up effort and the obtaining of death cer-
 tificates of those determined  to be  deceased.  Observed deaths will be compared to
 those expected  to uncover excess deaths .duejstq.,a particular cause.   Numerous indices of
 health will be  assessed through the  physii
 administered to the living members of the
                                                     inatlons and health questionnaires
  Further activities  tentatively include environmental exposure  and medical assessments
  of workers entering the industry.
  The Industrial Hygiene aspects of this study will be a Joint U.S. and USSR research
  project on the health effects associated with the oil shale industry.  William Wagner
  will make an initial trip to the USSR to develop joint US-USSR survey protocol.  A Rus-
  sian delegation headed by Dr. Gogovsky will then visit the U.S.  for approx. 3 weeks  in
  May 1977.  The Environmental Investigations Branch will be responsible for the planning
  of this trip.  Contact will be made with those people knowledgeable in oil shale tech-
  nology, -and those who are or have been involved in health studies related to oil shale
  mining and retorting.  Three industrial hygienists from the EIB are tentatively schedu-
  led to travel to  the Soviet Union in  September to perform walk through surveys of USSR
 IDENTIFY PBOFE£?OJNAL SCH?>&L INVOLVED r
 (fenfuf, t'lc.)
               None
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                           DATE

                                                                           Oct.  29,  1976
                                       FOB OFFICE USE ONLY
    SUPPORT METHOD (C/ioi-fc on.-)
Funds Estimate?*-'
    Z90K         76
                                  2  - ex
                                                PROJECT OFFICER
                                                 John  F. Finklea. M.D.
                                               RESPONSIBLE ORGANIZATION
                                                NIOSH
                      NO OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
                                                         STARTING DATE
                                                                            ESTIMATED COMPLETION
                                                                             11/78
*Funds approximate not for citation ANO s'-spe 76A WHICH MAY NOT BE USEa
                                            263

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          Form Approved
                                                                         OMB No.  U8-R0081
                                                                PROJECT NO. (Da not uae IMm

                                                                SSIE
                                                                 EPA-IAG-D6-E773--78 BCX
  rlTLE OF PROJECT
     Recommended Standards for Coal  Gasification Plants
 GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
     Murray L. Cohen, Project Administrator            Phone (301)443-3913
     DHEW/PHS/CDC/National Institute for Occupational Safety and Health
     Division of  Criteria Documentation and Standards Development
     Priorities and Research Analysis  Branch
 NAME AND ADDRESS OF APPLICANT INSTITUTION
     National Institute for Occupational Safety  and Health
     5600 Fishers Lane
     Rockville, Maryland  20852
 SUMMARY OF PROPOSED WORK - CD Objective*. CD Approach, <3) Curr.nl Plana and/or Frograas (200 word, or 1.... Omit confidential data).
    In the Smithsonian Science Information Exchange, summaries of work In pragreaa are exchanged with government and private aganclaa eup-
 riorting research and are forwarded to investigators who request such Information. Your summary la to be ya«d far theaa pvjrpoaaa.
          Guidelines for good work practices and  recommended occupational safety and
     health standards are being developed for coal gasification pilot plants.   Similar
     guidelines and recommendations will be developed for demonstration and  commercial
     scale  coal gasification plants.

          Pilot plant guidelines will be based on available world-wide  literature, and
     data that have been generated by federal agencies(EPA, ERDA).   Guidelines  for larger
     scale plants will be based on field data collected by NIOSH and extrapolations/
     predictions  from the data used in developing the pilot plant  guidelines.
          If implemented, these guidelines will provide some measure of worker
     protection from hazardous exposure.! until such time when formal standards  may be
     developed.

          Anticipated publication  date of pilot plant guidelines is Second Quarter,
     F? 77.  Anticipated publication date of guidelines for larger scale plants is
     October 1977.
  IDENTIFY PROFESSIONAL SCHOOL INVOLVE
  dfriKir, t-rr.)

            None
                                              TURE OF PRINCIPVL^/IVESTIGATOR
    SUPPORT METHOD (Ch.-rk on,.)
Funds Estimate^-*-
    100K
I   76
                                       FOR OFFICE USE/ONLY
                                    3- CX
                                                  IEANI
                                                  : O/i EC
                                                             DATE

                                                             October 12, 1976
                                                PROUECT OFFICER
                                                               John  F. Finklea,  M.D.
                                 RESPONSIBLE ORGANIZATION
                                               NIOSH
                       NO. OF FUTURE YEARS TEMTA1
                       ASSURED BEYOND CURRENT F/
                                                          STARTING DATE
        approximate not for Citation.: AND SI-SIE 76A WHICH MAY NOT BE USED.
                                                                             ESTIMATED COMPLETION
                                                                               1/77
                                             264

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                        OMB No.  IfS-ROOSI
                                             PROJECT NO. (Da not tat IMt

                                             SSIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                 EPA-IAG-D6-E773 - 78 BCX
  Industrial  Hygiene Study  of  Coal Gasification Plants
 GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

  Project Director:  Donald  F.  Knowlea, Jr.,  Indu3trial Hygiene Engineer; Phone (304)
    599-7421.
 NAME ANO ADDRESS OF APPLICANT INSTITUTION
  National  Institute for Occupational Safety  and Health, Appalachian Laboratory for
  Occupational Safety and Health, 944 Chestnut  Ridge Road, Morgantown,  W.  Va.  26505
 SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach. (3) Current Plans end/or Progress (JOO word! or lex. Omit confidential data).
    [n the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
 porting research and are forwarded to investigators who request such information. Your •ummary is to be used for theae purpoaea.

  This project is a contract  to perform  an  indepth industrial hygiene characterization
  of worker  environments  in three coal gasification pilot facilities.   The three pilot
  plants will be studied  at the rate of  one plant per year for  3 consecutive years. Each
  plant project will be divided into three  tasks.  Task I includes  a literature search,
  pilot plant walk-through, grab sampling,  laboratory analysis, documentation and descrip-
  tion of work places and a report of study proposal to the project officer.  Task II in-
  cludes qualitative area,  personal, and  bulk sampling, laboratory  analysis, documentatior
  of results and preparation  of a sampling protocol for Task III.   Task III includes
  quantitative detailed industrial hygiene monitoring, sample analysis  and determination
  of eight hour daily time  weighted average and  peak concentrations of  potentially hazard-
  ous substances.

  A final report for each pilot plant will be submitted by the  contractor and will in-
  clude;  (a) past & present worker exposure  (by  job)  constructed on the information that
  is collected on the changes in processing,  ventilation, environmental control, work
  practices; Cb)  industrial hygiene practices at the facilities; (c)  time weighted and
  peak concentration found  in the work place  for each job type;  (d) recommendations for
  control of worker exposures;  (e) identification of worker design  parometers for worker
  protection controls to  be integrated in demonstration and commercial  plant designs;
  (f) identification of additional problem  areas in the coal conversion industry requir-
  ing further research.
  IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.
  th-ntnl, i-rc.)

            None
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                           DATE

                                                            Oct. 29,  1976
                                        FOR OFFICE USE ONLY
     SUPPORT METHOD [Ou-i-k out-)
Funds Estimate
   15 OK
76
                                   3  -CX
                                           t.  Finklea, M.D.
                               RESPONSIBLE ORGANIZATION
                                     NIOSH
     NO OF FUTURE YEARS TENTATIVELY
     ASSURED BEYOND CURRENT F.Y.
                                                          ITARTING DATE
                                                              3/77
  unds approximate not for citation.  *»° *<•<»* «* «-'CH MAy NOT BE useo-
                                               265

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                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OP RESEARCH PROJECT
                                                                           Farm Afproved
                                                                         OMB No. i;»-ROOSl
                                                                 PROJECT NO. (Do not KM fill, mpmft)
                                                                 SUE
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                  EPA-IAG-D6-E773 -  78 BOX
  TTTLE OF PROJECT
   Industrial Hygiene Study of  Coal Liquifaction Processes
  GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
  PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

   Project Director:  Frank  J. Hearl,  Industrial Hygiene Engineer,
     Phone  (304)  599-7421
  NAME AND ADDRESS OF APPLICANT INSTITUTION
   National Institute for Occupational Safety and Health, Appalachian Laboratory for
   Occupational Safety and Health,  944 Chestnut  Ridge Road, Morgantown, W. Va.   26505
  SUMMARY OF PROPOSED WORK - (1) Objective*. (I) Appnach. (31 Current PleJU .od/or Profreoe (200 word. •» !•••. Oi>lt eoafUratlal itauj.
     [n the Smithionian Science Infermytlon Exchange, •unuiiorleB of work In propel* are •KClHnfVd with (.owrDBMOt and private a|OBCM>a aup-
  porline. research and are forwarded to Inveitlcatora who r*a.ue«t lucn Inforaiatloil. Tour mvamtry IB to bo vmd /or thOBO
   An RFC will  be developed for  the industrial hygiene study of  coal liquifaction processei
   Poorly contained coal liquifaction processes  produce emissions which evidence indicates
   may constitute a carcinogenic risk, especially for lung and skin cancer.   This study
   will address liquifaction products, process and material containment methods, worker
   exposures, health hazard control equipment, and the toxicologic properties of process
   materials.   Identification of liquifaction process health hazards in the developmental
   phase of the technology will  provide necessary information for health protection design
   considerations.  In order to  prevent long term effects in both workers and the general
   population,  Industrial hygiene findings and recommendations will be incorporated into
   present coal liquifaction technology development.

   The RFC will require an industrial hygiene program that includes a complete  literature
   search, a preliminary survey,  a qualitative survey and a quantitative survey.  The
   overall objective will be an  in-depth industrial hygiene characterization  ofxworker
   environments in coal liquifaction plants.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (JWcrfi

                None
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                              DATE

                                                                               Oct.  29, 1976
                                        FOR OFFICE USE ONLY
     SUPPORT METHOD (C/i.-i-k orn->
      AGENCY STAFF flnfra
 Funds Estimate ¥

 |    125K	 76
                                     4 t CX
                                                 PROJECT OFFICER
                                                   JOHN F. FINKLEA,  M.D.
                                               RESPONSIBLE ORGANIZATION

                                                  HTOSH	
                     NO. OF FUTURE YEARS TENTATIVELY
                     ASSURED BEYOND CURRENT F.t.
                                                          STARTING DATE
ESTIMATED COMPLETION
DATE
"TFunds  aporoximate not for citation.5 *NO S|-SIE 76A WH1CH MAY NOT BE USED-
                                              266

-------
                   U.S. ENVIRONMENTAL PROTECTION AGENCY
                     NOTICE OF RESEARCH PROJECT
                                                                                       Ftant A
                                                                                     nun NO.
                                               PROJECT HO. (Oo nuf „„» «,;„

                                                HIE
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                               EPA

                                                 EPA-IAG-D6-E773- BCX
    Coal Liquifaction and Gasification Worker Health Effects  Conference
  GIVE HOMES. DEPARTMENTS. ANG OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL Ol HER
  PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   NAME A»O ADDRESS OF APPLICANT INSTITUTION
    National  Institute for Occupational Safety  and  Health
   SUMMARY OF r'&OfOSEO *OI«K - (I* Ul.j<'< liv.->. *2> Appromh, (J> Current Plans unO/or Prci.r*»s (200 word* or lets.  Omit confidential dato).
     In Ik* SniHh*<«niitn S*'ien« »* Infi/rnu'tiun Kx> h:mi;i<, Humtnarirs vf work in prpur0»K are exchanged with cuvernmcm arut private •f.enclet tup.
     line w*r.i-arch timl urr furwurdcd Iti lnvealteutorn who request Kucb lnfi»rinatlon. Your •umflury i» lo be us«d for [he«c purpoaei.
           PHOrLSSIONAL SCHOOL INVOLVED l
                                                  SIGNATURE OF PRINCIPAL IN VESTIGE
             r MITIIOP c !*'«•*• fc «'m.'L_
      f*CI NCV SI AIT (fttir..f>.i*r.i/t
                                               FOR OFFICE USE ONLY _ 	
       ut srAHCM GH*yjI
 Funds Estlmate|T.v.
  |   25,000       I 76
*Tunds approximate  not for citation.
                                                         pRCSPONSIdLC yROANJZATlON
                                                              Hioa«        	
NO Of MITIMU  VI. ANS TtNTATIVLLY
AabUHI.U UtYOND CUHHLNT F.Y.
                                        STAHTINC. OATE
tSIIMATEO COMPLETION
UATt
                                                                 8/77
                                                  267

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          fttrnt Appro
                                                                         OMK No. L
                                                                 PROJECT NO. (tlo ma t/«« Ihl, ipactt

                                                                 551C
                                                                 EPA
                                                                   EPA-IAG-D6-E773- 78
TITLE OF PFimitiN  The
 National Air Quality Advisory Committee has suggested that particulates be studied
 not as  total suspended  particulate but according to particle size distribution.

 The findings of the  CHESS study  strongly suggest that occupational exposures to  sulfatei
 need  further study in terms of exposure levels and mortality experience.

 This  project will continue to determine exposures to a variety of soluable and in-
 soluble sulfates  in  a number  of  industries.   These data will be used to choose popu-
 lations for mortality studies beginning in FY'77.  The study will also be devoted'to
 supporting field  testing of the  sampling and  analytical methods.
lOHNTIIY PROFESSIONAL SCHOOL INVOLVEt) fAlr.«.-.rf.
ifi-nr.il. .-It-. >
             None
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                               OATE

                                                                                  Oct. 29,  1976
                                       FOR OFFICE USE ONLY
                                    7-CX
                                                PROJECT OFFICER
                                                          ORGANIZATION
      7( 11 AMCH O I* AN T
      Estimate ]».v.  INO. or Furunr YEARS TEMTArTv-CL1
 I    32. 8K         76  I *S5UMt ° et VONO CUHREHT r.v.
Funds approximate  not for citation.
                                                         STARTING OATE
                                                                             tSTIMATFO COMPLETION
                                                                             OATE
                                                                              1976
                                          268

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                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                            Pnrm Approved
                                                                          (MIH Nn. I
                                                                 PROJECT NO. (Du nut use ttili'stmco)

                                                                 SSIE
                                                                 EPA
                                                                   EPA-IAG-D6-E773-  78 BCX
    Morbidity and Industrial Hygiene Study of Workers Exposed to SO ,H2,SO,,NO ,HNO
      rto  DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AKO ALL OTHER '
  PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   Project  Directors:   John Gamble, Epidemiologist and William G. Jones, Industrial
     Hygienist,  Phone:  (304) 599-7421
  NAME AND ADDRESS OF APPLICANT INSTITUTION
   National Institute  for Occupational Safety and Health,  Appalachian Laboratory for
   Occupational Safety and Health, 944 Chestnut Ridge Road, Morgantown,. W.  Va.   26505
   SUKMMtY OF r>HC,r-OOCD WOFtK - (|) bl.j.-. li%r>. (21 APIKO.C!., (3) Current Plan, and/or Profess (200 words or kit. Omit confidential data).
     tn tfM* SinilliKiNiiiin Srk-ni-«- liifi.rmiilinn KttnunKi'. xummariet of work in progress are exchanged with government and private agencies sup-
   I'arlint: n-sr-jiri-h iin'l «re furwurded i«> investigators whg reo/jest such information. Yogr summary It to be used for these purposes.

     Sulfur oxides  (SO )  and sulfuric acid mist  (H.SO^)  are upper and total  respiratory
     irritants.  Over ?00,000 workers are potentially  exposed.  Nitrogen oxides  (NO ) and
     nitric acid (HNO-)  are primarily lower respiratory  tract irritants.   Over 1-1/2 millio
     workers are potentially exposed.  The toxic  effect  of these compounds derives pri-
     marily from the fact that they are strong acids,  or from corrosive  acids on contact
     with moist mucus membranes.  Many documented cases  of acute over-exposure indicate
     their irritating and toxic  properties.  Effects of  low-level chronic exposure are
     not  known, and  there is little information on dose-response relations.   Both N02 and
     SO.are common  air pollutants.  Acute effects of exposure will be etermined  in workers
     exposed to relatively pure  mixture of sulfur.and  nitrogen compounds. Pulmonary func-
     tion tests will be administered  before and after  work, while simultaneously measuring
     environmental  exposure to the  individual chemical species.  Chest x-rays will be
     taken, and the prevalence of acute and chronic  respiratory symptoms, body burden
      (methemoglobin, urine, and  salivary pH) and  dental  erosion will be  determined.  An
     estimate of total cumulative exposure from work histories will be used  to determine
     chronic effects.
   IDENTIFY I'HOfESSIONAL SCHOOL INVOLVED (.Wi'di.'.i
    iLlf. t'fr.)
                None
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                              DATE

                                                                               Oct.  29, 1976
                                         FOR OFFICE USE ONLY_
            MtTMOP tt'fi.
     TMISI-MICM tf'MN'
Funds EstimateT'.Y
                                      7-CX
                                                 PROJECT OFFICER
                                                      John  F.  Ftnklea,  M.D^
                                                 RESPONSIBLE ORGANIZATION
                                                       NIOSH
EsttaateVY.--HNo.oHrt-F^
            76  I       ...
 ,|    268.4X       /o   i
T'unds approximate not for citation.
                                                           STARTING DATE
                                                                              ESTIMATFO COMPLETION
                                                                              DATE
                                                                                  1976
                                            269

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                        OMB No. 118-R008!
                                                               PROJECT NO. IDa no, u>, fill, apace;

                                                               SSIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                EPA-IAG-D6-E773 - 78 BCX
  riTLE OF PROJECT
      Assessment of  Safety in Energy  Industries
 GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AHO ALL OTHER
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
      Project Director:   Richard Wlberg
        Phone:  (304)  599-7331
 NAME AND ADDRESS OF APPLICANT INSTITUTION
      National Institute for Occupational Safety and Health, Appalachian Laboratory for
      Occupational  Safety and Health,  944 Chestnut Ridge Rd., Morgantown,  W.  Va. 26505
 SUMMARY OF PROPOSED WORK - (1) Objective.. (J) Approach, (J) Current PUn. end/or Progress (200 wort, or less. Omit confidential data).
    In the Smithsonian Science Informal Ion Exchange, luminaries of work In progress are exchanged with government and private agendas sup*
 porting research and are forwarded to investigators who request such information. Yoor summary is to be used for these purposes.

      The energy  shortage will result  in an accelerated expansion in the  energy produc-
      ing industries  which makes these critical installations  even more vulnerable  to
      mishaps.  Accidents and catastrophic incidents not  only  affect workers at these
      workplaces  but  the entire  surrounding population who  would be exposed to pollut-
      ants, toxic fumes,  explosions and fires.  The loss  of resources and energy pro-
      duction have a  critical economic impact on the nation.   As a consequence, the
      project will therefore prove to  be of serendipitous benefit to other  federal
      governmental agencies such as EPA, ERDA and DOT and cooperation and coordination
      with these  agencies will be maintained.  Since regulations of nuclear plants are
      not under the specific authority of  ERDA, these facilities are not  included within
      the scope of this  project.  Energy industries employing  workers covered under the
      Occupational Safety and Health Act and utilizing fossil  fuels and petroleum (liquid
      and gaseous hydrocarbons) will be assessed as to safety  problems, particularly
      fire and explosions, which would indicate vulnerability  in life safety of the
      immediate population.  Accidents involving two or more injuries or  one fatality
      will be tabulated,  explored and  studied in case histories from on-site investi-
      gations.  The final report will  contain recommendations  for future  actions that can
      be implemented  within a reasonable expenditure of funds.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
 drntnl, ffr.)

              None
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
DATE

  Oct.  29, 1976
                                       FOR OFFICE USE ONLY
    SUPPORT METHOD (Chrct on,->
     RESEARCH GRANT
Funds Estimate
I  100K	
                JZfi
                                     9- CX
                                                PROJECT OFFICER
                                                 John  F. Finklea.  M.D.
                                                RESPONSIBLE ORGANIZATION
                                                  NIOSH
                                                         STARTING DATE
ESTIMATED COMPLETION
OATF
  T1976
      approximate not for Citation « ANOSI-SIETSA WHICH MAY NOT BE USED.
                                             270

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                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
                                                                           Form Approved
                                                                         OMB No. DS-R0081
                                            PROJECT NO. (Do not use this epacej
                                            SSIE
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                   EPA-IAG-D6-E773 - 78 BCX
  Mortality and Ind.  Hyg.  Study of Workers in Coal Fired  Power Plants (TVA)
   GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

        Project Directors:   Dr. Carl Ortmeyer and William L. Wagner
          Phone:  (304)  599-7421
   NAME AND ADDRESS OF APPLICANT INSTITUTION
       National Institute  for Occupational  Safety and Health, Appalachian Laboratory for
       Occupational Safety and Health,  944 Chestnut Ridge Rd., Morgantown, W. Va. 26505
   SUMMARY OF PROPOSED WORK - (I) Objective. (2) Approach. (3) Current Plans mad/or Progreaa (JOO words or lese. Omit confidential data).
     In the Smithsonian Science Information Exchange, summaries of work in progress era exchanged with government and private agencies •up-
   porting research and are forwarded to investigators who request such information. Your summary Is to be used for these purposes.

    Pulmonary disease problems, particularly  pneumoconioses and airway obstructive diseases
    could  arise from exposure to pollutant  gas  emissions such  as  S02 and  NO,, from coal
    burned as fuel for steam-powered electricity  generating plants.  Pneumoconioses could
    develop from years of  exposures to coal dusts in coal-loading areas or to asbestos
    fibers in linings of steam pipes.

    The primary purpose of this- study is to measure specified  effects  (decreased longevity,
    "premature" deaths from pulmonary diseases, and early retirement due  to  disability
    attributed to such diseases) on high risk workers in coal-fired  steam electricity
    generating plants who  have had exposures  to these pollutants  that  varied in duration
    and intensity.

    In  the process of collecting information  on early disability  and on mortality of em-
    ployees exposed to these air pollutants,  data will also be obtained on neoplasms of
    the respiratory system and on diseases  of the heart.  This  evidence can  be analyzed
    in  relation to some hypotheses about carcinogenic effects  of  pollutants  and effects
    on  the heart or lung  impairments.
    The TVA and the Environmental Investigations  Branch will jointly conduct preliminary
    Industrial Hygiene surveys to select approx.  10 potentially hazardous occupations  in
    TVA coal-fired plants.  TVA will then  conduct detailed cross-sectioned Industrial
    Hygiene Studies of workers invloved in these  "potentially  hazardous"  occupations.  TVA
    shall  also review existing industrial  hygiene data on past  exposures  in  the potentially
    hazardous occupations  along with information  on control methods  in order to retrospec-
    tively estimate cumulative working lifetime exposures in the  identified  hazardous  oc-
    cupations,                                  (continued on reverse  side)
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Aforffc-.-./,
   denial. f»c.)
               None
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                         DATE

                                                           Oct.  29, 1976
                                         FOR OFFICE USE ONLY
      SUPPORT METHOD tCVu'Cfc t
       RESEARCH GRANT
 Funds Estimate?
     57.1
75
                                   10 - CX
                                                  PROJECT OFFICE
                                                              John F.  Flnklea,  M.D.
                                                  RESPONSIBLE ORGANIZATION
                                                              NIOSH
    NO. OF FUTURE YEARS TENTATIVELY
    ASSURED BEYOND CURRENT F.Y.
                                                          STARTING DATE
                                                                              ESTIMATED COMPLETION
                                                                 7/88
*Funds approximate not for citation, s AND ,,.,,e ™* »H,CH MAY „,
                                                           IOT BE USED.
                                             271

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                           Form Approved
                                                                         OMB No. 1S8-KOOS1
                                  PROJECT NO. (Do not usa ffila

                                  SSIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                 EFA-IAG-D6-E773 - BCX
 TITLE OF PROJECT
     Medical Study  of Divers
 GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
  Project Director:   Joe Costello
    Phone: (304)  599-7307
                    PLICANT INSTITUTION
  National Institute for Occupational Safety and Health,  Appalachian Laboratory for
  Occupational Safety and Health, 944 Chestnut Ridge Road., Morgantown, W. Va.  26505
 SUMMARY OF PROPOSED WORK -  (I) objectives, <2> Approach, (3) Currant Plan, .ml/or Progress (200 word* or less.  Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and prlvata agencies sup-
 porting research and are forwarded to Investigator* who request such information. Your summary la to b« uavd for theae purpoeee.

   The purpose of  the study is  to establish  a  base  line of the incidence, distribution
   and control of  diving related illnesses in  the commercial diving industry.   Physio-
   logical hazards are not limited to symptoms of inadequate decompression such as bends.
   Equally serious in the long  run are problems relating  to pulmonary and vestibular
   function, brain damage, hearing loss,  and dysbaric osteonecrosis.

   Because of the  complexity  of the problems,  plus  the  fact that we are continually
   operating at  the edges of  medical and  technical  knowledge, long  term studies are
   required, especially in hyperbaric medicine, which are not likely to be done by the
   individual diving companies.

   During the first quarter a review of the  literature  and past NIOSH contracts will be
   done.   A protocol and study  plan will  be  worked  out  and then submitted for  contract
   bid.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Mcclidtl.
 1/..MMI. ,•(!'.)

            None
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                               DATE

                                                 Oct.  29,  1976
                                       FOR OFFICE USE ONLY
  X  AGENCY ST App (7'lf r.lnmrill)
.Funds Estimate^
    156.7
ASK NO.


    11- CX
PROJECT OFFICER
   John F. Flnklea.  M.D.
                                                 RESPONSIBLE ORGANIZATION
                                                     NIOSH
                       NO. OF FUTURE YEARS TENTATIVELY
                       ASSURED 9EYOND CURRENT F.Y.
                                                          STARTING DATE
                                               ESTIMATED COMPLETION
                                               DATE
                                                   9/78
       approximate not for citation. AND s|-s|e76A »HICH MAY NOT BE USED.
                                             272

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              U.S. ENVIRONMENTAL PROTECflON AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        Form Approved
                                                                       OMB No.  138-R0081
                                                               PROJECT NO. (Do not use this ipmce)
                                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE
          JECT
                                                                EPA-IAG-D6-E773-- 78 BCX
. . . __ OF PROJE_.
Develop  Criteria for  Recirculation  of  Industrial Exhaust Air
 IIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

Project Director:   Robert Hughes
  Phone: (513) 684-4295
NAME ANO ADDRESS OF APPLICANT INSTITUTION
National Institute  for Occupational  Safety and Health,  Division of Laboratories
and  Criteria Development, Cincinnati,  Ohio  45202	
SUMMARY OF PROPOSED WORK -  (I) Objectives, (2) Approach, (3) Current Plan, and/or Progress (200 words or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary Is to be used for these purposes.

 Since  the advent of the energy crisis, recirculation  of industrial process exhaust
 air  has been receiving widespread  attention as an  energy conservation  method.   Re-
 circulation of  process exhaust air to the workplace rather than to the outside will
 reduce the amount  of  heating or  cooling of make up air  with a significant  reduction
 in energy usage.   Recirculation  of exhaust air has, in  the past, been  used infre-
 quently and has essentially been limited to processes which generate nontoxic
 nuisance type dusts.   The major  limiting factor in the  widespread use  of recircula-
 tion for toxic  materials is the  lack of criteria relating  to both system performance
 and  work protection.   Without such criteria, the use  of recirculation  systems  could
 result in serious  worker exposure  to toxic substances.

 This project will  be  a follow-on to a study initiated in FY 74 to develop  criteria
 for  the recirculation of exhaust air.  The results of that initial contract  effort
 will be evaluated  and a symposium  then held on recirculation of exhaust air. After
 this,  a one-year contract will be  awarded to develop  the exhaust system performance
 and  reliability criteria required  to permit safe recirculation of exhaust  air  from
 processes which generate toxic gases, vapors, fumes and particulates.  Studies will
 also be made to determine the effect of process variables  such as temperature  and
 contaminant generation rate on system effectiveness.  Another follow-on contract
 will be awarded to investigate the air cleaning devices necessary to permit  recircu-
 lation of exhaust  air.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED fMciiic.il,
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD (C/i,'i-Ji
    RESEARCH GRANT
                                   12  - CZ
                                                PROJECT OFFICER
                                                  John F. Finklea. M.D.
                                               RESPONSIBLE ORGANIZATION
                                                   NIOSH
p.. -.Jo
rUndS

I   TTL.2
                     Two. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
                76   I
                                                        STARTING DATE
                                                                            ESTIMATED COMPLETION
                                                                            DATE
                                                                               9/77
       approximate not for citation- AND
                                                WHICH MAY NOT BE USED.
                                           273

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          Form Approved
                                                                        OMB No. D8-R0081
                                                               PROJECT NO. (Do not tiae tnia epacej

                                                               SSIE
                                                                 EPA-IAG-D6-E773-78 BCX
TITLE OF PROJECT
 Mortality Study of  Small Fibrous  Glass Workers
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AMD ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Project  Director:  David Bayliss
   Phone  (513) 684-2761
NAME AND ADDRESS OF APPLICANT INSTITUTION
 National  Institute for  Occupational Safety and Health, Division of Surveillance, Hazard
 Evaluations and Field STudies,  4676 Columbia Parkway,  Cincinnati, Ohio   45226
SUMMARY OF PROPOSED WORK - (I) Objective,, (2) Approach, (3) Current Plans and/or Progreea (100 word! or loss. Omit confidential d»l»>.
  In the Smithsonian Science Information Exchange, aummariem of work in progreaa are exchanged with government and private agenclea sup-
porting research and are forwarded 10 investigators who request such information. Your summary la to be used for theae pwpoaea.

 A recently completed study of  fibrous  glass workers at a plant in Ohio failed to
 demonstrate any increased mortality due to malignant respiratory disease.   However,
 increased mortality  was  noted  due  to non-malignant  respiratory disease in  the same
 study  population.  The  failure  to  observe an excess of malignant respiratory disease
 in this  population possibly may have been due to  the fact that the major portion of
 the study group was  generally  exposed  to fibers of  larger diameter, which  generally
 have not been shown  to  be carcinogenic in man or  animals.

 This study proposes  a retrospective mortality study on a sub»-cohort of the entire
 working  population who  were subjectively determined through  a double-blind study to
 be exposed to fibers with diameters from 1 micron to 3 microns in diameter, a range
 suspected of having  carcinogenic potential to man.   It must  be cautioned,  however,
 that this study will not answer the question of carcinogenesis with respect to the
 fine fiber (less than 1  micron  in  diameter).
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
   SUPPORT METHOD fOi.'t-k 0/1.-)
    AGENCY STAFF (Intramural)
    RESEARCH GRANT
Funds
I40.2       ' 76
                                      FOR OFFICE USE ONLY
                                 6 -
                                               PROJECT OFFICER
                                                John F.  Finklea, M.D.
                                                 RESPONSIBLE ORGANIZATION
                                                   NIOSH
                      NO. OF FUTURE YEARS TENTATIV
                      ASSURED BEYOND CURRENT F.Y.
                                                         STARTING DATE
      approximate not for Citation. AND SI-SIE 76A *HICH MAY NOT BE USED.
                                            274

-------
                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                           Form Approved
                                                                         OMB No. 1H-R0081
                                                               PROJECT NO. (Da not ua« tfile epacej

                                                               5SIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                               _	
                                                                EPA-IAG-D6-E773- 78 BCX
  Mortality and Industrial Hygiene  Study of Workers Exposed to Mineral Wool
 GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
  ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
  Project  Directors:   Ralph Zumwalde and Greg Ness
    Phone  <±S (513) 684-2761
 NAME AND ADDRESS OF APPLICANT INSTITUTION
  National Institute  for Occupational Safety and  Health
  Division of Surveillance, Hazard  Evaluations  and Field Studies
  4676  Columbia Parkway,  Cincinnati, Ohio  45226
 SUMMARY OF PROPOSED WORK - (1) objectives. (2) Approach. (3) Currant Plan, and/or Progrees (200 word, or 1.... Omit confidential data).
    tn the Smithsonian Science Information Exchange, summaries of work In progress ar« exchanged with government and private agencies .up-
 porting research and are forwarded (o investigator, who reque.t >uch information. Your summary i» to be u»«d for these purposes.
  In  view of the  vast quantity of  health data demonstrating  the  carcinogenicity  of
  asbestos  fibers,  insulation and  other Industries  have begun searching for substitute
  materials to replace asbestos.   However, the  fibers constituting  these substitute
  materials may be  similar in shape  and size to that of asbestos.   It  is felt by many
  researchers that  the morphology  of the fibers is  the most  important  factor in  the
  development of  malignant and non-malignant respiratory disease.

  Therefore, since  little is known of the health effects to  man  of  resplrable fibers
  other  than asbestos,  it is incumbent upon the National Institute  for Occupational
  Safety and Health CNIOSH) to investigate epidemiologically the human health conse-
  quences of respirable fiber exposures and other insulation materials.

  This  study will be approached  through environmental surveys and mortality studies
  designed to quantify the risk  of exposure to  mineral wool  used as well as determine
  the presence of other substances that may promote the development of adverse health
  effects or act  in a synergistic  manner.
  IDENTIFY PROFESSIONAL SCHOOL IN VOLVED (
  tlflttfll. ffC.)
                  None
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                                 Oct.  29, 1976
                                        FOR OFFICE USE ONLY
     SUPPORT METHOD (Clirrk urn-)
      NEGOTIATED CONTRACT
                                    6  -  CX
                                                                       ,  M.D.
                                                RESPONSIBLE ORGANIZATION
                                                  NIOSH
Funds
I     70.8
                        NO  OF FUTURE YEARS TENTATIVELY
                        ASSURED BEYOND CURRENT F.Y.
                   76
                                                          STARTING DATE
                                                                              ESTIMATED COMPLETION
*FundS approximate not for citation. AND S.-S^SA WHICH MAY NOT BE USE
                                                275

-------
                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
                                                                            Form Approved
                                                                          OMB No. 1S8-R0081
                                                                 PROJECT NO. (Da ml lue this spacej
                                                                 5SIE
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                  EPA-IAG-D6-E773 -78 BCX
  TITLE OF PROJECT
   Mortality and Industrial Hygiene  Study of Workers exposed to  Clay Fibers
  GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
  PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.

   Project Director:  Greg Ness, Epidemiologist and  Ralph Zumwalde, Industrial Hygienlst
     Phone (513) 684-2761.
  NAME AND ADDRESS OF APPLICANT INSTITUTION
   National  Institute for Occupational  Safety and Health, Division of Surveillance, Hazard
   Evaluations and Field  Studies, 4676  Columbia Parkway,  Cincinnati, Ohio   45226
  SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach. (3) Current PUuu and/or Profreae (200 word* or loss,. Omit confidential data).
     In the Smithsonian Sci«nc.e Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
  porting research and ure forwarded to investigators who request such information. Your summary la to be uaad [or Uleae pia-poaes.

   In the  process of studying the chronic health hazards from occupational exposure to
   respirable fibers such as asbestos,  fiberglas, and  mineral wool,  the xstd National In-
   stitute for Occupational Safety and  Health has identified additional flberous  minerals
   which SXEXX are of  occupational health concern.   Attapulgite, one constituent  of a grouj
   of substances collectively known as  "Fuller's Earth", is one  such mineral fiber which
   has been discussed  with  chronic lung disease.

   A mortality study of  a population with an  occupational exposure to Attapulgite of
   approximately thirty  C30)  years since onset of exposure is being  conducted.  This will
   permit  investigation  of  long term chronic  health  effects of exposures to small diameter
   short mineral fibers  by  a study population with sufficient latency.

   An industrial hygiene study has been completed and  data analysis  is  underway.
  IDENTIFY PROFESSIONAL SCHOOL INVOLVED f

            None
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                                 Oct.  30.  1976
                                         FOR OFFICE USE ONLY
     SUPPORT METHOD [Ch.-.-fc on,')
Funds
     64,500
                   76
                                      6 - CX
                                                  PROJECT OFFICER
                                                      John  F. Flnklea.  M.n.
                                                  RESPONSIBLE ORGANIZATION
                                                      NIOSH
                        NO. OF FUTURE YEARS TENTATIVELY
                        ASSURED BEYOND CURRENT F.Y.
STARTING DATE

       6/75
                                                                                    5/78
** Funds approximate not for citation,; AND SI-SIE ?SA *HICM MAY NOT BE USED.
                                              276

-------
                 U.S. ENVIRONMENTAL PROTECTION AOENCY
                   NOTICE OF RESEARCH PROJECT
                                                                           Form Approved
                                                                          OMB No. I18-R0081
                                                              PROJECT NO. (Do not us* thim space;

                                                              SSIE
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                              EPA	
                                                              EPA-IAG-DG-E773-78 BCX
    Develop Analytical Methods to Determine  OCC Exposure  to  H?SO,Sulfate.Suflite.HNO..& HCL
   IIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHCRZ
   •ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
    Project Directors:  Janet C. Haartz, Ph.D., Supv. Research Chemist, MEB.DPSE and
      Peter M.  Eller, PH.D.,  Research Chemist,  MRB, DPSE
      Phone:  (513) 684-2628
   NAME ANO ADDRESS OF APPLICANT INSTITUTION

    National  Institute for Occupational Safety and Health,   4676 Columbia Parkway,
    Cincinnati,  Ohio  45226
   SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (JOO worts or less. Omit confidential data).
     In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agenclea sup-
    ortine research and are forwarded 10 investigators who request such information. Your summary la to be used for these purposes.

    Fossil  fuels contain varying amounts of  sulfur and nitrogen.   In combustion  of these
    fuels,  with air, oxidized  forms of sulfur  and nitrogen are  released into  the occu-
    pational  environment as well as to the  general environment.
    elemental sulfur, sulfur oxides (adsorbed  SO, and SO,) and  HjS may be
    Nitrogen species include nitric acid and metal nitrates  and nitrites,
 In addition,  a number of  sulfur and nitrogen  species are present  in air samples  in
 smelters,  refiners, and other industries.   Sulfur may be present  in the form of
 sulfuric acid, and metal  sulfates, sulfites,  thiosulfates, and  sulfides.  Also,
                                                                        be present.
                                                                           and oxides
 of nitrogen (NO- and NO).   Separation and  quantitation of these sSnri±EB species
 are desirable for assessment of their effect  on health.  Analytical methods using
 ion exchange  chromatography, polarography,  specific ion potentiometry, ESCA, or
 others which  differentiate  the oxidation states of sulfur and nitrogen are needed.
 This project  will evaluate  the alternatives available and develop protocols for
 sampling/analysis of these  species.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED f.Vo,

              None
                                            SIGNATURE OF PRINCIPAL INVEST
                                                                                Oct.  29, 1976
                                         FOR OFFICE USE ONLY
      SUPPORT METHOD (C/"'fh
        GENCY 5T AFF (/M/r.lmlirJ/)
       RESEARCH GRANT
                                   7a&b -  ex
                                               PR°JJohn FFr Finklea,  M.D.
                                               RESPONSIBLE ORGANIZATION
                                                    NIOSH    	
  Funds Estimate*^-
      93K
                   76
                                                                                   10/78
*Funds approximate not for citation.- -° »«>' ™ -"'™ "" »°T 8E U5ED-
                                            277

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                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE Ut  f-tiOJtCT
     Energy Industry Medical  Protocols.
                                                                                    O.lffl Nn.
                                                                            PROJECT NO. (Do nut UNO thtt
                                                                            ssie
                                                                              EPA-IAG-D6-E773-  78   BCZ
GIVE NAMES. OLPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AMD ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
NAME AND ADDRESS OF APPLICANT INSTITUTION
  MMAi'Y OF f'NOF'ODLO WO^K -  (1) O*-j« i tiv.-t.. (2) Approach, (3) Curre-nt Plan* «m!,'or Profiros (200 wards or |c»*.  Omit confidential (Uld).
   In 111.- Smh;.suni:ifi S« ti-nt •• ln(..tr».,t Jon Km h.mni.-. sumrrwirtr* of work in progr.*** ur«- CKChanged with government mrui private *e*ncl't« »u[>-
  rlim; M-K.-ur4.li ,ir,.i Hr« furwurdvtJ to invf tli(;u(c«s who re-quest such iitfurmillion. Your vuninury i« to bt used (or these purpose*.
         PKOrCSSIONAL SCHOOL INVOLVED f.l.
       -.J
               None
                                                SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                                           DATE
                                                                                              Oct.  29,  1976
   SUPPORT METHOD (Oi.vi ..»i,-)
      i NO  ST *f r f/ri
   X I N I CO 1 I A T 1.1* C ON f H A I' 1
                                             FOR OFFICE USE ONLY _____
                                 See  BCX   AP
                                          8-  CZ
                                                                _____
                                                       PROJECT OFFICER
                                                                               John  F.  Ftnklea,  M.D.
                                                         'HEiPON&IBLE ORGANIZATION
     , FM SI AHCH CHAN 1
Funds Estimate?* .•    ~~] NO. OF t UTUKI- YEARS i LNT *vi IVLLV
 I    150K         I 76    J««OHIOBIVOND CURRENT r.y.
        approximate not for citation.
                                                                                 NIOSH
                                                                  STARTING DATE
                                                                                         ESTIMATLO COktrLETION
                                                                                         °"E  1976
                                                   278

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D.  ECOLOGICAL EFFECTS

-------
                       TABLE OF CONTENTS
                        Ecological Effects
Agency




 EPA




 ERDA




 NIEHS




 NOAA




 TVA




 USDA
  Page




279-300




301-311




312-314




315-316




317-327




328-331

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OP RESEARCH PROJECT
                                                                        Form Approved
                                                                      OMB No. US-ROOSl
                                                           PROJECT NO. (Do not (Ma t
                                                           ssie
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                   CMB
                survey in the violaity of the XETOLA oil spill, Xagellan Strait, Chile.
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
                                        . CMtUlo, Eepartmeut of Marine Biolosr and Ocea--
   ography. University of Concepeion, Concepcion, Chile.
   Dr*. Richard C. Swturtz «ad Donald J, Baamgartaer,  Maria* and Freshwater Ecology Brand
   EPA, JUrtne Science Center, Hevport, Oregon 97365  (503)367-4031.
NAMEANO ADDRESS OF APPLICANT INSTITUTION                      .                   .       ,,,  -,,-
          "of Concepcion, Department of Marine Biology and Oceanography, Caailla 1367
University
Coacepcion, Chile
SUMMARY Of PROPOSED WORK - (1) Obf*etiv»«. (2) Approach. (3) Cumm PUlw and/or Pracr«l* (200 wofds or !•••. Omit eonrLd«mi>[ dau).
   In the Smithsonian Science Information Exchange, •unourioi of work in proffr*** mrm exchanged with gorvrnmont and private aaaacles aup-
   lni research and are forwarded to invealiaator* who requaet auch Information. Your ctunmary ia to be used for theaa purposes.
   A. To quantitatively doscritio  the faanal composition, density, gtaading crop, diver-
      sity, dominance, and apatial  heMgeneitr of the  suWidal maerooenthoa of Sahia Fe-
      lipe, the  aite of the METCIJ.  apill, and  imediate nei^tboring areaa.

   B. To correlate changes ia conmmity otruetnre with depth, bottoa water quality, and
      sediment oharacteriaties, aapecially oil eontaadnation. particle  size distribution
      and organic  carbon content.

   C. To establish a reference  collection of beathio invertebrates for  future tazonoaie
      comparisons.

      The survey Mill be performed through standard  quantitative benthic biology tech-
      niquea on board B/7 HERO. A T-T^^g grid has  been designed to observe the impact
      of oil both  from the source of the spill and the area* where it wa» finally
      deposited. Fauna! numerical,  gravimetric and taxononio analysis will be followed
      by statistical-BAthcuutical treatment of the data to determine several of the
      important  bio-indices useful in the understanding of possible alterations of the
      biota by the spilled oil.

      The sampling is expected  to take place in the  coming southern autnnn from H/V
      SEF.O  by  a binstional teaa of US and Chilean  scientists.
   Biology Ifflrtitut*. TJept.  BlolJtar,
                                      FOR OF^Itf
   SUPPORT METHOD (
                                   2C"
                                               RESPONSIBLE 0«G-AN|-Z*TIQN
                                                ERLf CorvalliS''-' .^
 FUNDS OBLIGATED | F.Y.
                    NO  OF FUTURE YEARS TENTATIVELY
                    ASSURED BEYOND CURRENT F.Y.
                                 0
 EPA F.r«.57«0-l (7-72)    REPLACES PMS FORM 186 AND SI-SIE75A »MICH MAY NOT SE USED.
                                            279

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        Form Approved

                                                                       OMB No.  l}g-ROOSl
                                                              PROJECT NO. (Da rial u<« Ihlt ip.caj

                                                              SSIE
                                                                   CMB
TMontanaRCoaY-Fired  Power Plant Bioenvironmental Study
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OB PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Dr.  N.  R.  Glass, Director                  Dr. R. A. Lewis
 Ecological Effects Research Division       Terrestrial  Ecology Branch,  EERD

 Dr.  Lawrence Raniere,  Chief
 Terrestrial Ecology  Branch, EERD	
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Corvallis Environmental  Research Lab,  USEPA
 200 SW 35th Street
 Corvallis. OR 97330          	
SUMMARY OF PROPOSED WORK - {[) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or le*ft. Omit confidential data).
  In i hi- Smiihsoni.in Scionct- Informal ion Exchange, summaries of work in progress are exchanged with government and private agencies sup-
 The two objectives  of this program  are:   (1) to develop  procedures which  can be
 used to forecast  and assess the impacts  of stressants  from energy producing activities
 on affected ecosystems; and (2) to  identify and describe the impacts for  a given set
 of ecosystems.

 The approach is to  combine field measurements with on-site field experimentation and
 laboratory process  studies.  Remote sensing, modelling activities, and other
 associated supportive efforts_will  be  utilized to maximize the activity.

 The Corvallis Environmental Research Laboratory has mounted a field effort in
 Montana.  Besides the normal field  facilities (mobile  air quality laboratories,
 biological analysis systems, etc.)  an  effort has been  made to coordinate  the project
 with other scientific centers (Grassland IBP, ERDA, EPA  and NOAA) to include the
 necessary scientific and engineering expertise to guarantee a unified program.  It is
 intended that the research information gathered from this project be utilized in such
 a fashion that  a  set of biological  parameters are found  that will allow planning
 managers to project cost/benefit relationships prior to  locating an energy producing
 facility.
 OENT1FY PROFESSIONAL SCHOOL (N VOL V ED ( V.-.llY. ll
:/, r-r.i/. ,-u:t
                                                                               •P 2 B 1976
                                      FOR OFFICE USE ONLY
   SUPPORT MtTMOO (O....J. „„. \
  $437,000
76
                                               PROJECT OFFICER
                                                 Dr. Norman  R.  Glass
                                               RESPONSIBLE ORGANIZATION
                                               Corvallis Environmental Research Laboratory
ASSURE.O BE'YOND CURRENT F.Y,
  Two  Years
                                                        STARTING DATE
FY 74
                                                           ESTIMATED COMPLETION
                                                           DATE
                                                                 FY 79
EPA Form 5760-1 (7-72)    REPLACtS PHS FORM 166 AND St-SIE 76A WHICH MAY NOT BE USED.
                                            280

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                            Farm Approved
                                                                          OMB .Vo. DS-ROOS1
                                          PROJECT NO. (Da not ua* tfifa

                                          SSIE
  Sffact of Temperature oa  Growth and Survival  of the Hhice Sucser
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
  Lloyd L.  Soith,  Jr.. Professor, Dept. of Eatocology, Fisheries,  & Wildlife
  Walter M. Koenst,  Assistant Scientist, Dept.  of Entomology, Fisheries, a Wildlife
NAME AND ADDRESS OF APPLICANT INSTITUTION
  University of Minnesota
  2642  University Avenue
  Minneapolis, Minnesota 55455
SUMMARY OF PROPOSED WORK - (1) Objectivea, (2) Approach, (3) Currant Plan* and/or Procreas (200 word* or !••*. Omit confidential data).
   In the SmithaonUn Science Information Exchange, aummariei at work in progreaa era exchanged with government and private agencies tup-
portinf feiearch and «re forwarded to Inveatigators who requeat auch information. Your aumrnary ia to be uaed toe theae
     The first objective  of the project is  to determine the growth rate of Catostonua
  cooaersoai under different teoperature regimes and  to construct  response curves
  that  ra" be related to  food consumption.   Subordinate objectives are (1) to
  Uetsraine the  iaf lueuce of size on growth response  at different  temperatures  and
  (2) to deterniae the relationship of optiaua teisperature to incipient lethal
  temperatures.   A second objective is to determine the influence  of reduced  rations
  as coaparad to ad libitua rations on the  optiaum taaperature for jrovth in  three
  size  groups of fish.  Dad will be gathered and analysed in a form which will
  provide input  to ecosystea aodeling.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED ('Medjcal,
dmntal, ere..)
   Agricultural
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                                 1/23/76
                                        FOR OFFICE USE ONLY
   SUPPORT METHOD (Check onej
    AGENCY STAFF (Intramural)
    RESEARCH GRANT
FUNDS OBLIGATED

 fo, 2.98
                                 ID
                          PROJECT OFFICER
                                       okOi*»..aa.iri
                                   e ORGANIZATION
NO. OF FUTURE YEARS TSNTATIVEL
ASSURED BEYOND CURRENT F.Y.
STARTING DATE

  7//0/76
EPA Form 5740.1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                          281

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                  U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
         PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                             Form Approved
                                                                            OMB No.  158-ROOSl
                                                PROJECT NO. (Do not use this space;
                                                SSIE	            	
                                                ^EA~
                                                         CNA
     itydrofogfc"characterization of Coal Spoil  Piles 1n northwest Colorado
   GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
     Georga Laavesley, Principal  Investigator,  USGS - Water  Resources  uiv.-Colo.  Lfist. Jff.
     Denver Federal Center, Oenver,  Colorado  80225
     J.E.  Bieselker, Project Supervisor (Same as  above)
   NAME AND ADDRESS OF APPLICANT INSTITUTION
     J.E.  Bieselke
     Sane  as above
   SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or lest. Omit confidential data).
    ^ In the Smithsonian Science Information Exchange, summaries of work In progress are exchanged with government and private agencies sup-
   porting research and are forwarded to Investigator* who request such Information.  Your summary is to be used for these purposen.
           Tbb purpose of this project Is to study the hydrologlc characteristics  of
     coal  spoil piles west of the Edna Mine in Routt County,  Colorado.   The effort
     is designed to complement on-going studies  by Colorado State University on the
     voter qulaity degradation potential of mine spoils.   Specifically,  the project
     will  examine trace metal concentrations and movement; consider the  moisture
     regime of the spoils profile; examine changes in undisturbed areas;  and develop
     a  model  to predict the impact of disturbed  areas on  total  basin  response.
     Lysimeters will  be installed and a rainfall  simulator will be used.   Water samples
     will  be taken from observation  wells.  Soil  moisture probes will be  utilized.
    IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medic,:,
    dental, ere.)
                                            SIGNATURE OF PRINCIPAL INVESTIGATOR
                                          FOR OFFICE USE ONLY
      SUPPORT METHOD fCf.ec* one;
Funds Estimate*
     $555,000
76
                                                   PROJECT OFFICER
                                                   Dona Id I*  Mount
      NO. OF FUTURE YEARS TENTATIVELY
      ASSURED BEYOND CURRENT F.Y.
                                                   RESPONSIBLE ORGANIZATION

                                                   EPA/ERL-Duluth
STARTING DATE

   1975
                                                                               |June  1978
       approximate not for Citation. tee AND SI-SIE ?SA WHICH MAY NOT BE USED.
                                                 282

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               O.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                             Form Approved
                                                                           OHO No. 118-R0081
                                                                  PROJECT HO. (Da not an Mile tpme»)
                                                                  ssie
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE

TITLE OF PROJECT
                                                                       CPA
   Thermal Effects of Energy Utilization  In Combination With Other Pollutant  Stresses
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIOATORS OH PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
   Dr. Don Miller

   Dr. Juan Gonzalez

   Dr. Eugene Jacklm
NAME AND AOORESS OF APPLICANT INSTITUTION
   Environmental Protection Agency
   Environmental Research Laboratory
   South  Ferry Road, Narragansett, RI
                                             02882
SUMMARY OF PROPOSED WORK - (1) objectives, <2> Apf.ro.ch, (3) Current Plan, end/or Progress (200 word, or !••>.  Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work In progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such Information. Your summary is to be used far these purposes.


         Extramural studies, inconjunction with  in-house studies, on a different
   geocllmactic  province,  will  be conducted which will provide a defensible basis
   for applying  thermal elevation criteria to all areas under tie jurisdiction
   of  EPA.   Such studies will recognize  the interactions between thermal  stress
   and those resulting from simultaneous  or intermittent stresses from other
   sources.


         Studies  on water accommodated fractions of  oil, such as might be  discharged
   from drilling platforms are  being supported  in-house.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED fflladjcal,
 4/erafa/. efc.)
                                           SIGNATURE OF PRINCIPAL INVESTIGATOR
                                         FOR OFFICE USE ONLY
    SUPPORT METHOD fOirc* eni-J
 xxl
               - (Iniratiniral)
    RESEARCH GRANT
 FUHOS OBLIGATED

     86,000
                 F,Y.

                  76
                                                  PROJECT OFFICER
                                                   Dr.  Donald'K. Phelps
                                                  RESPONSIBLE ORGANIZATION
                                                    ERL-Sarragansett
                                                                               838-4843
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                                                           STARTING DATE
                                      Continuing
6/79
 EPA Form 5760-1 (7-72)     REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                               283

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                         Form Approved
                                                                       OMB No. IJ8-R0081
                                                               PROJECT NO. (Do not uae thlm apace>

                                                               551E
                                                                       CPA
TITLE OF PROJECT	
   A FACILITY FOR THE EXPERIMENTAL ANALYSIS  OF COASTAL MARINE ECOSYSTEMS
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCASED IN THE PROJECT.
   Dr. John A. Knauss, Dean            Mr. James Griffin, Project Manager
   Dr. Scott Nixon
   Dr. Michael Pilson
   Dr. Theodore  Smayda
NAME AND ADDRESS OF APPLICANT INSTITUTION
   Graduate  School of Oceanography
   University of  Rhode Island
   Kingston,  Rhode Island    02881
SUMMARY OF PROPOSED WORK-  (1) Objective., (2) Approach, (3) Current Plan, and/or Progreea (200 word* or leea. Omit confidential dull).
   In the Smithsonian Science Information Exchange, •ummsrica of work In progreaa are exchanged with government and private agencies sup-
porting roaearch and are forwarded to InveatigatorB who request auch information. You summary la to be uaed for these purpoaea.

   (1)  Objectives:
        a)   to develop a  facility and methodology for the  experimental  analysis of
             coastal marine  ecosystems and their response to energy-related environ-
             mental stresses
        b)   to relate  the experimental  results to ecosystem theory and  its
             implications  for the management of coastal marine  environments.
   (2)  Approach:
        Replicate meso-scale experimental ecosystems simulating a variety of common-
        coastal marine environments will  be developed and  maintained  at a special
        shore-based laboratory.  A number of  stresses or environmental  perturbation
        associated with  energy development will then be  applied over  a  range of
        intensities to these systems before,  during and  after  the application
        of  stress.  Similar field experiments may also be  carried out on a small
        scale in some  environments.

   (3)  Current Plans:
        The first project will involve  9  shore-based experimental water columns
         (5  m deep x 2  m  dia.) with associated bottom sediments and benthos.  The
        microcosms will  first be studied  for  repllcability and for differences
        between tanks  that  are run as open or closed systems with respect to
         seawater flow.   After this preliminary work  is completed, a  series of
         experiments involving the addition of water  soluble petroleum hydro-
         carbons at concentrations of 100  and  1000 ug/1 will begin.
dental. efc.)
             ilONAL SCHOOL INVOLVED (Medical,
    Graduate School of  Oceanography
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD (Check one)
                                               PROJECT OFFICERi
                                                Dr. Eric  D.'Schneider
                                               RESPONSIBLE ORGANIZATION
                                                ERL-Harragansett, RI -  EPA   838-4843
FUNDS OBLIGATED
   985,000
F.Y.
 76
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                                                        STARTING DATE
                                                         7/22/75
                                                               7/30/78
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                             284

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                       OMB No. 118-R0081
                                        PROJECT NO. (Da nor use rjifs space>

                                        SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                   CPA
 ITLE OF PROJECT
 National Marine  Pollution Monitoring Program
 IVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 ROFESS1ONAL PERSONNEL ENGAGED IN THE PROJECT.
 Edward D. Goldberg,  SS# 548-18-011, Professor  of Chemistry
 Geological Research Division
 Scripps Institution of Oceanography
NAME AND ADDRESS OF APPLICANT INSTITUTION
 The  Regents  of the University  of California
 University of  California,  San  Diego
 Ta Tnllfl  raUfnrrHa   P20Q3
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plan, and/or Progress (200 words or lex. Oral! confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agenclex sup-
porting; research and are forwarded to investigator! who request such information. Your summary la to be used for these purposes.

  A surveillance of four collectives of pollutants in U.S. coastal waters is being
  carried out  through their  concentrations in two sentinel organisms—mussels and
  barnacles.   The pollutant  species include heavy metals  (lead,  cadmium, mercury,
  selenium,  zinc, silver and copper), chlorinated hydrocarbons  {DDT  residues,
  polychlorinated biphenyls,  hexachlorbenzene,  dieldrin, endrin,  heptachlor, benzene
  hexachloride,  cis and trans chlordane and  the insecticidal derivatives oxychlordane
  and heptachlor epoxide), artificial radionuclides  (plutonium-238,  plutonium-239+240,
  americiem-241  and cesium-137), and petroleum hydrocarbons  (to include measures of
  the concentrations of alkanes, cycloalkanes and aromatlcs,  including 2, 3, 4  and
  5 ring polynuclear condensed species).

  The program includes sites off the east, west and Gulf coasts of the U.S. as  well
  as off Alaska, Guam and  Samoa.  Over  two hundred and  fifty samples will be taken
  during the first two years of the project  and analyzed in  8 laboratories, two for
  each set  of pollutants.  Interlaboratory comparisons  are being made on the pollutant
  analyses.

  The goals of the program will be the  assessment of  the U.S. coastal waters for the
  support  of marine resources such as food from the  sea,  the Vitality of communities
  of marine organisms and  the continued use  of non-living resources such as beaches
  and harbors and  the prediction of future exposure  levels of pollutants based  upon
  the best  existing information and models.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED fMo
 dental, etc.)

  Scripps  Institution  of  Oceanography
                                          SIGNATURE OF PRINCIPAL INVES
    SUPPORT METHOD (Check t
    AGENCY ST AFP (litirarr.ttrjt}
                                       FOR OFFICE USE ONLT
                         PROJECT OFFICER
                          Dr.  Ge-rald Hoffman
 FUNDS OBLIGATED  F.Y.
  315,000
                                                RESPONSIBLE ORGANIZATION

                                                 ERL-Narragansett. RI    838-4843
                  76
HO OF PUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                                                         STARTING PATE
                                                          12/75
                                                                            ESTIMATED COMPLETION
                                                                            DATE
                                                         12/77
 F.PA Form 57.0-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WH.CH MAY NOT BE USED.
                                               285

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              U.S. ENVIRONMENTAL PHI.   ^TION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        Form 'Approved
                                                                       O.Vf) No. ;JS-ROOSJ
                                                              PROJECT NO. I Do nor u»e Ihil space)

                                                              SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                    CQB
TITLE OF PROJECT  Studies  on environmental chemical carcinogens  presenc in economicaiiy-
           mr.11iisr-s and crustaceans from Oregon bays, estuaries and inshore  areas:
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 Dr. Michael C. Mix
 Associate Professor  of  Biology
 Department of General Science
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Oregon State University
 Corvallis, Oreeon  97331
SUMMARY OF PROPOSED WORK - (l) Objectives. (2) Approach. (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
porting research and are (orwarded to investigators who request such information* Your summary is to be used for these purposes*
      The principal  objectives are:   to determine the concentration of  selected
environmental carcinogens in economically-important molluscs and crustaceans  from
Oregon bays, estuaries  and inshore  areas; to determine  if there is a potential public
health hazard from  consuming shellfish which contain carcinogenic petroleum by-products;
to survey populations of bivalve molluscs,  determine the incidence of  neoplastic
diseases in these populations and ascertain if there is any correlation  between
carcinogenic body burdens and incidences of such diseases;  to determine  if metabolic
pathways exist  in bivalves which lead to detoxification or modification  of benzo(a)-
pyrene; to determine tne acuce and  ciu.uuic etr«:i-L= ol c^oiin^, ^cllusccr. ;r.d
crustacean gametes  and larvae to selected chemical carcinogens, and evaluate the
ecological consequences of such effects.

      Seven economically-important shellfish will be  sampled monthly during a two or
three year period and the following studies will be  conducted:  quantitative and
qualitative determinations of  chemical  carcinogens present in shellfish; histopatho-
logical examination of bivalves for neoplasfic diseases; studies related to
benzo(t»)pyrene  metabolism and  rates of  uptake, incorporation and elimination in
natural populations of shellfish.   Following completion of this research, personnel
from appropriate  state and federal  agencies will  evaluate the public health implications
of our findings.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
dental, ere.)
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                           Sfpyember  14,  1975
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD JOTecIc one)
                                               PROJECT OFFICER         -.
                                                    "Dr.  Tc-U  A,.  C
                                               RESPONSIBLE ORGANIZATION
                                                                           '' < a *
FUNDS OBLIGATED
               F.Y.

                76
NO. OF FUTURE YEARS TENTATIVELY
ASSURED 9EYONO CURRENT F.Y.
STARTING DATE

   till TG
ESTIMATED COMPLETION
DATE    .
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                             286

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TITLE OF PROJECT                                         ^~~~~-"^——•
Field  Investigation of Brominated and Chlorinated Organic Compounds
             U.S. ENVIRONMENTAL PROTECTION AGENCY
              NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                              Form Approi'cd
                                                            OMfi No. 158-R0081
                                  PROJECT NO. (Do nol use this sp.ce]

                                  SSIE
                                       CQB
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR I
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
                                    George R.  Helz
                                    Chemistry Department
                                    301-454-4850
                              also  Rong  Yew Hsu - same  address
NAME AND ADDRESS OF APPLICANT INSTITUTION
                              University of Maryland
                              College Park, MD  20742
 SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach. (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
 porting research and «ri: forvvurdfd to investigators who request such information. Your suntmary is to be used for these purposes.
         Amounts of chlorine preseirS£yrflS£d in  the drainage basin of
 Chesapeake Bay, and probably also  some other  large estuaries,  could be
 large  enough to sterilize the  Bay  if this chlorine were not  degraded.
 A review of degradation proces.ses  reveals that  perhaps 1% of the total
 chlorine may be converted to halogenated organic compounds,  and it is
 suggested that some of these may be long-lived  and susceptible to
 biomagnification.   Arguments are given to indicate that organic
 compounds produced  by chlorination of estuarine and marine waters may
 differ fundamentally from those  produced by chlorination of  river water
 and  sewage in that  bromine derivatives may predominate over  chlorine
 derivatives in the  marine waters.

         A research project is proposed to test these ideas in the field
 near a power plant  which employs 4-15% estuarine water for  cooling,
 and  chlorinates this to control  fouling.  The site is free  of  other
 nearby anthropogenic sources.  The objectives of the project will be:
         1. Identify  and quantify  the halogenated organic compounds
            produced  by the plant.
         2. Determine chemical factors controlling yields of  the various
            compounds by studying  the cooling waters under a  variety
            of conditions.

         The project  will provide  an evaluation of the magnitude of this
 problem and may provide some indications of how the problem can be min-
 imized by regulation of chlorinating procedures and cooling water quality
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED f.\;(.(/(c../.
          Graduate School
                                   SIGNATURE OF PRINCIPAL INVESTIGATOR
   SUPPORT METHOD Oi.-cfc
                         	FOR_OFFICE USEJJNLY
                       TTASK NO.
    RESEARCH GRAST
                                         PROJECT OFFICER
                                                    Dr. William Davis
                                         RESPONSI8LE ORGANIZATION
                                         - BBFS, Gulf Breeze,  Florida
 FUNDS OBLIGATED  F.Y.
      73K     76"
NO OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.T .
                                                                Rug.  1,  1977
 EPA Form 5760-1 (7-72)   REPLACES PHS FORM 166 AND SI-S'E 76A WHICH MAY NOT BE USED.
                                      287

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                            Form .\pprufV" FUTUflC YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
STARTING DATE
7/15/7 S
ESTIMATED COMPLETI3*
DATE
    7/14/77
EPA Form 5760-1 (7-72)     REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT 8E USED.
                                            288

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY-
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
 ITLEOF PROJECT
                                                                  CQB
      ing nf vpnnhinHcs through estuarlne and marine  sediments
.ivg NAMES, OEPAPTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
'ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
  Charles N. D'Asaro
  Norman I. Rubinstein
                      Associate  Professor
                      Research Associate
Dept. of  Biology, Univ. West  FL
Dept. of  Biology, Univ. West  FL
 ^ME AND ADDRESS OF APPLICANT INSTITUTION
  University of West Florida

  Pensacola. Florida  3250*1	
SUMMARY OF PROPOSED WORK - (I) Objecliv.«. (2) Approach. (31 Current Pliru and/or Pn

porting research and ar« forwarded to Investigators who request such Information.  Your aumma
         This  research will  examine a mechanism of cycling for  various xenobiotics  in
  and through  estuarine  and  marine sediments.   A lugworm, Arenicola cristata
  (Polychaeta:   Arenicolidae),  will be studied to define and quantify movement of
  compounds  through the  sediment as a result  of reworking and biological accumulation.
  Experiments  are designed  to determine,  (a)  how lugworms move  xenobiotics  into
  and through  the substrate  when the compounds are introduced  into the overlying
  water  column; (b) how  effectively lugworms  move sorbed xenobiotics from
  various  depths in the  sediment to the  surface and (c) what volume of sediment
  could  be exposed to xenobiotics due to reworking by  lugworms.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.

 'unfversity of West Florida
  _Qfi
-f-monl- nf Rinlnny
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD fCliccfc one;
 X
                                         'ROJECT OFFICER
                                           Dr.. Frank G.  Wilkes
                                         RESPONSIBLE ORGANIZATION

                                           Gulf Breeze.  Florida
 FUNDS OBLIGATED | F.Y.

                6
               NO OF FUTURE VEARS TENTATIVELY
               ASSURED BEYOND CURRENT F.Y.
STARTINT DATE
 4/1/76
                                          289

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              U.S. ENVIRONMENTAL PROTECTION ACCNCV
                NOTICE OF RESEARCH PROJECT
                                                                        f'orm Aftftrui'fd
                                                                      OMB ^fo. 15R-R0081
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCilAHGE
                                                  CQB
TITLEiOF PROJECT
Isolation and  Study of Chloro-orp.anies RnGultir.g from Chlorination of  Seawater
Give NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Dr. James H.  Carpenter, Chairman,  Division of Chemical Oceanography, Univ.  of Miami

Mr. Carroll A.  Smith, Research Associate Professor, Div.  of Chem. Oceano. U. of Miami
NAME AND ADDRESS OF APPLICANT INSTITUTION .
University  of Miami, Rosenstiel  School of Marine and Atmospheric Science
 600 Pwictenbacker Causeway
Miami, Florida 33149
SUMMARY Or PROPOSED WORK - (1) Ohjc
                               s. (2) Approach. (3) Current Plans and'or Progress {300 words or te*3.  Omit confidential data).
     The  proposed i-esearch peaks  to  identify the chlorine-containing and  broai.ne-
containing  organic compounds that ara formed when chlorine in added to  neavater.
Initial enphasis would, be placed  on  study of reaction  conditions that occur during
power plant operations; i.e., up  Co  2 hours at temperatures up to 30"C  with and without
sunlight.  Total organic halo£t>nated compounds yield uould be measured.   The reaction
products  would be fractionated, usiug selective solubility and thin layer chromato-
graphy.   Characterisation i:ould be carried out using gas  chromatosraphic-iysss spectral
techniques  and additional characterization would be based on UV and IR  spectra with
  R for special cases.
 IQENTIrY PRO F t SS I O N A L SCHOOL INVOLVED / Mi-,1,1-,,1,
 "'•"'•"• ••"••'Rosensticl School of Marine
and Atmospheric Science
                        SIGNATURE OF PRINCIPAL INVESTIGATOR

                                  'f          -^-'-
                                      FOR OFFICE USE ONLY
 FUNDS ODLIGATFD
 $160, 000
76
                                                (OJtCT OP TIGER
                                                • Dr. William P. Davis
                                               RESPONSIBLE ORGANIZATION
                                                 BBFS,  Gulf Breeze, Florida
STARTING OATC
     I   I   —

7/15/75,
                                                                             7/14/78
 EPA Form 5760-1 (7-72)    REPLACES PUS FORM 166 AND St-SlE 76A WHICH MAY NOT BE USED.
                                      290

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                             Form Approved
                                                                           O.MB No.  1J8-R0081
                                           PROJECT NO. (Do not use thts space)

                                           SSIE
                                                                  EPA~
                                                                          CQB
  Effects  of Energy Related Pollutants  on Organisms and  Ecosystems
 ilvE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 'ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.


  Dr. Norman Richards,  Mr.  Patrick Borthwick, Mr.  Stephan Schimmel, Mr.  Lowell

  Banner,  Mr.  James Patrick, Mr.  Sam Tagatz, Mr.  James Moore.
NAME AND ADDRESS OF APPLICANT INSTITUTION
  U. S.  Environmental  Protection Agency
  Environmental Research Laboratory
  Sabine Island, Gulf  Breeze,  Florida   32561
SUMMARY OF PROPOSED WORK - <1> Objectives, (2) Approach, (3) Current Plans and/or Progress <200 words or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup.
porting research and are forwarded to investigators who request such information. Yowaummary is to be used for these purposes.



  Offshore petroleum exploration and  extraction activities may  affect  marine and

  estuarine  environments.  The objective of this research is to  assess  effects of

  resultant  chemical emissions on representative organisms and  communities.

  Bioassays  using drilling muds and their components will involve a variety of

  test  species and toxic effects.
IDENTIFY PROFESSIONAL SCHOOL INVOLVEO fAh
cjcnrji, ffr.J
                                             GNATURE OF PRINCIPAL INVESTIGATOR
                                                         DATE


                                                          Sept.  30,  1976
                                         FOR OFFICE USE ONLY
    SUPPORT METHOD fCtiuck un
     RESEARCH GRANT
                           PROJECT OFFICER
                               Dr. Norman L.  Richards
                                                  RESPONSIBLE ORGANIZATION
                                                       Gulf Breeze, Florida
 FUNDS OBLIGATED
NO OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
                                                              10/77
                                                                                   10/78
 EPA Form 5760-1 (7-72)     REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                           291

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                        OMB No. 1}8-ROO$1
                                                               PROJECT NO. (Do not use thla apace)

                                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                     CSA
 Re1atiPonsinp of Biological, Chemical and Physical Characteristics of the.
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT. ...SflR  JUdO RlVer tO  the LilHIOlOCJy 3Hd
 Bob Thomas, Principal Investigator      ecological productivity of  the San Juan  Arm
                                            of Lake Powell
NAME AND ADDRESS OF APPLICANT INSTITUTION
 EPA - Environmental  Monitoring  and Support  Laboratory
 Las Vegas, Nevada
SUMMARY OF PROPOSED WORK -  (1) Objectives, (2) Approach, (3) Current Plans find/or Progress (200 worde or leu. Omit confidential date).
  In the Smithsonian Science Information Exchange, flummarles of work in progress are excnaneod with government ancj private agencies sup-
porting research aid are forwarded to Investigators who request such information. You- summary is to be used for chase purposes.
       In the  near future the San  Juan River  Basin will be subjected to  considerable
  pressures to develop its energy  and non-energy resources.   Such actions  oould
  have major impact on the biological, chemical  and physical  Integrity of  the
  San  Juan River, Lake Powell and  downstream  environments.
       A study of the San Juan  River and the  San Juan Arm  of Lake Powell was initiated
  to further define baseline environmental conditions In the states areas.  Data
  collection will emphasize phytoplankton, zooplankton, invertebrates, water chemistry,
  soil caemlstry, sediment chemistry and physical parameters.
       Major objectives are to  assess the ecological Importance of the San Juan Arm
  of Lake Powell, Its dependence on the San Juan River and its relationship to the
  greater Lake Powell exosystem.   Heavy metal  contributions to the San Juan River
  System are to  be further delineated with determinations  made on the  possible
  effects of heaby metal concentrations on the biological  resource.
       In addition, information collected as  part of the study will provide input
  to the design  of an optimum environmental monitoring system for the  San  Juan
  River Basin  by EPA-EHSL.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD fChect one)
    RESEARCH GRANT
                                 1 C
                                               PROJECT OFFICER
                                               RESPONSIBLE ORGANIZATION
                                               EPA, Region VIII, Denver
FUNDS OBLIGATED

   20 K
76
      NO. OF FUTURE YEARS TENTATIVELY
      ASSURED BEYOND CURRENT F.Y.
                                                         STARTING DATE
                                                              6/76
                                                                6/77
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT SE USED.
                                            292

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                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                         OMB No. 158-R0081
                                              PROJECT NO. (Do

                                              S51E
                                                                             lot use thia apace)
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                fpT"
                                                   CSA
     —
    Chemical  and Bacteriological  Analysis of Stream Sediments in the  Knife River Basin...
  OWE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
  PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.   . . . of ilOrtH DakOt3
    Dr. Mary Bromel, Principal  Investigator, Experiment Station - College  of Agriculture
    ;iD State University -  Fargo, North Dakota   58102

    Arlon  Hazen, Project Supervisor (Dean a  Director Morth Dakota State  University)
  NAME AND ADDRESS OF APPLICANT INSTITUTION
    Arlon  Hazen, Experiment  Station - College of Agriculture
    ilorth  Dakota State University, Fargo, North  Dakota  58102
  SUMMARY OF PROPOSED WORK - (1) Objective*, (2) Approach. (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
     In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
  porting research and are forwarded to investigators who request such information. Your summary is to be used for theae purposes.
         Assessment of  the  chemical  and biologiaal  status of sediments  in the Knife
     River  and its tributaries  relative to ethrophying  nutrients, pathogenic  bacteria,
     toxic  chemicals and self purification potentials of surface waters.
         A major objective  of  this study is to obtain  baseline data  for stream sediments,
     determine sediment  chemical  quality and characterize sediment associated bacteria
     for  a  representative segment of the Knife River drainage that could be significantly
     impacted  by future  energy  development.
         A second major objective is to study data  to  enable assessment of sediment -
     bacteriological interrelationship for an area already impacted by  pollution
     loadings  from coal  mine activities.   Ideally a  site  within the interior  drainage
     area of an active mine  where waste has accumulated.   The second  site would be an
     area which has been impacted for years.
         Criteria used  for  selection to establish baseline conditions  should emphasize
     areas  where there 1s a  high  probability for  energy"^development,  an  area  within
     the  drainage development which has not been  significantly disturoed by energy
     development, and an area where surface water drainage patterns are  significantly
     defined so that future  energy impact on surface" water can be assessed wich a
     reasonable degree of accuracy once development  occurs.  The above  described
     second sampling site, an area already impacted  by  pollution loadings should
     provide information on  the long-term effects of sediment loadings  of coal  mina
     activities on sediment  related bacteria.  Sampling of the baseline  sites should be
     more frequent than  of the  impacted environment  sites.
  IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
  dental, etc.)
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                        FOR OFFICE USE ONLY
     SUPPORT METHOD (Check one)
      AGENCY STAFF (Intramural)
      NEGOTIATED CONTRACT
                                                Cooper H*  Wayman
                                                 PROJECT OFFICER
                               RESPONSIBLE ORGANIZATION

                              EPA -  Region VIII
Funds Estimate*
    $20,000
76
      NO OF FUTURE YEARS TENTATIVELY
      ASSURED BEYOND CURRENT F.Y.
STARTING DATE

 1 June 1976
                                                           30  June  1977
Funds approximate not for Citation. i« AND SI-SIE 76A WHICH MAY NOT BE USED.
                                           293

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                        OMB No.
                                                               PROJECT NO. (Do not KM Mil* (pace)

                                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                   CSA
                  Studies - Tongue River, Montana
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
  Ken Bouee, Principal Investigator,  Univ. of  Montana, Geology Dept., Missoula, MT
  James Gore,  Investigator, Univ.  of  Montana,  Sane as above
  Dr. Arnold Silver-man, Univ.  of Montana (Project Supervisor)  (Same as  above)
NAME AND ADDRESS OF APPLICANT INSTITUTION
  Dr.  Arnold Silverman
  Univ.  of Montana,  Geology Dept., Missoula, Montana  59301
SUMMARY OF PROPOSED WORK -  (1) Objectives, (2) Approach, (3) Current Plan* and/or Progress (200 word! or fell. Omit confidential d>U).
   In the Smithsonian Science Information Exchange. summaries of wca-k in progreBB are exchanged with government and private agencies sup.
porting reeearch and are forwarded to investigators nrho request such information. Your summary ie to be used for theee purpoees.
       A methodology is needed  to  predict the effects of changes in warm water stream
  flows on plant and animal ecosystems.   In  order to develop this methodology a
  research plan was  established which provided  for a literature search,  a proposed
  methodology,  and field testing of the proposed methodology.
       Field testing, modification and verification of  the methodology o«curred
  on the Tongue  River, Montana  and was conducted in two phases.   The first phase
  established  tolerance limits  and habitat preferences  of biotlc communities
  under naturally  occurring stream conditions.   Baseline biological data  was
  also collected.
       Phase two Involved the application, evaluation and modification of the
  methodology  within the Tongue River drainage.   This work characterized  the effects
  of flow variation  on a range  of  habitat requirements  for important aquatic species
  during summer and  winter conditions.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED rttodics/.
dental, etc.)
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD (Check c
    AGENCY ST a F F (Intramural)
Funds Estimate^
  I  $12.7  K
                                               PROJECT OFFICER
                                               Cooper H.  Wayman
                                               RESPONSIBLE ORGANIZATION

                                               EPA-Region VIII
               F.Y.

               76
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
STARTING DATE

 May  1, 1976
                                                      November  1,  19'
    approximate not for Citation.  '66 AND SI-SIE ?SA WHICH MAY NOT BE USED.
                                           294

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                  U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
                                                                            Form Approved
                                                                          OMB No. U8-ROOS1
                                              PROJECT NO. !Do not ua« this spaced

                                              SSIE
        PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                 CSA
     Effects  of Energy Development on the  Aquatic Resources  of Two Upper Missouri	
   GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT. ...ReServoie Ec0SyStemS
     B111 Nelson
     Principal  Investigator
     liorth  Cente«l Reservoir Investigations,  USFUS
     Pierre,  South Dakota
   NAME AND ADDRESS OF APPLICANT INSTITUTION
     Same as  above
   SUMMARY OF PROPOSED WORK - (1) objective*. (2) Approach, (3) Cujr.nl Plan, and/or Progress (200 word, or less. Omit confidential data).
      In the Smithsonian Science Information Exchange, summaries of work in progre*. are exchanged with government and private agencies sup-
   porting research and are forwarded to investigator, who request such information.  Your summary is to be used for these purposes.

          Objectives
     a.   Inventory and characterize the  biological, physical,  and chemical conditions
          of Ft. Peck Reservoir, Montana,  and Lake Sakakawea,  North Dakota in  areas of
          current and/or potential energy  development.
     b.   Identify and rank  all known and anticipated impacts of energy or energy-
          related developments on the aquatic biota and water  quality of these reservoirs.
          These items would include, but not be limited to,  liquid and atmospheric waste
          emissions from coal conversion facilities, water withdrawals, construction
          activities, land  use patterns, municipal wastes, energy transportation,  etc.
     c.   Develop a simple mechanism, e.g., a matrix, to integrate data from a  and  b
          above so that  the cumulative effects of energy  development at various levels
          of intensity on the reservoir  ecosystem can be  predicted.
     d.   Based on information from a, b, and c, develop strategies, criteris,
          and guideline  recom mendations to:
          (1) provide realistic development  alternatives  to  minimize damage to the
               aquatic environment;
           (2) mitigate losses resulting  from energy development,  and
           (3) where possible, utilize development-related environmental modifications
               to enhance water quality and fish and wildlife  habitat.
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
                                            SIGNATURE OF PRINCIPAL INVESTIGATOR
                                         FOR OFFICE USE ONLY
      SUPPORT METHOD (Check one)
                                                  PROJECT OFFICER
                                                  Cooper  H. Wayman
                                                  RESPONSIBLE ORGANIZATION

                                                  EPA-Region VIII
Funds Estimate"*
  j $20.000
76
     NO. OF FUTURE YEARS TENTATIVELY
     ASSURED BEYOND CURRENT F.Y.
STARTING DATE

June  1,  1976
June  30,  1977
       approximate not for citation.  '66 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                              295

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                  U.S. ENVIRONMENTAL PROTECTION AGENCY
                    NOTICE OF RESEARCH PROJECT
                                                                             Form Approved
                                                                           OMB No. US-R0081
                                                                   PROJECT NO. (Dor

                                                                   SSIE
                                                                                  tae tMm apace)
                                                                  EPA-
         PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                        CSA
    TITLE OF PROJECT	
    Fishery Investigations  - Poplar River
    GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
    PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
    Robert iieedhatn
    NAME AND ADDRESS OF APPLICANT INSTITUTION
    Montana  Department of Fish and Game
    Glascow,  Montana
    SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 worda or leaa. Omit confidential data).
      In the Smithsonian Science information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
    porting research arid are forwarded to investigators who request such information. Your summary is to be used for theae purposes.

    The  Saskatchewan Power Corporation  is peesently developing  a coal-fired power generating
    complex on the East Poplar River.   Construction of a cooling reservoir  (run-of-the-
    river)  was initiated  in 1975.  The  project could significantly alter the flow regimen
    of the  Poplar and  adversily impact  water quality.

    The  Poplar River system contains a  good sport  fishery consisting of Walleye,  Northern
    Pike, Bass, and Goldeye.   Fish population studies  were initiated in 1975 to acquire
    oaseline information.   Seining and  electrofishing  were conducted to determine species
    abundance and distribution (adult).

    The  objectives of  this  study are to gather quantitative data on the abundance and
    distribution of young-of-the-year walleye, northern pike, and  smallmouth bass at
    selected sites in  the  Poplar drainage.  In addition,  all records of stream  discharge,
    water quality, and temperature will  be secured and evaluated to determine possible
    ir,pact  on sport fish  populations.
    DENT1FY PROFESSIONAL SCHOOL INVOLVED (Medical.
    dental, etc.)
                                            SIGNATURE OF PRINCIPAL INVESTIGATOR
                                          FOR OFFICE USE ONLY
       SUPPORT METHOD (Check ortej
        NEGOTIATED CONTRACT
       RESEARCH GRAN
                                                    Cooper H. Wayman
                               RESPONSIBLE ORGANIZATION

                                EPA -  Region VIII
 Funds Estimate^*
   I  $3,650
76
      NO. OF FUTURE YEARS TENTATIVELY
      ASSURED BEYOND CURRENT F.Y.
                                                            STARTING DATE
June  1, 1976
                                                            June 30, 1977
*Funds approximate not for citation. ,66 ANO S|.SI£ 76A WHICH MAY NOT BE USED.
                                               296

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                   U.S. ENVIRONMENTAL PROTECTION AGENCY
                    NOTICE OF RESEARCH PROJECT
         PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                             Farm Approved
                                                                           OMB No. US-RODS';
                                               PROJECT NO. (Do not use this

                                               SSIE
                                                                      CSA
      Surface Water Quality Monitoring Program 1n Canadian  Coal  development  Impact fireas.
    GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
    PROFESSIONAL PERSONNEL ENGAOED IN THE PROJECT.	of ti16 Pop! 3r R1 V6r - Montana
      Mr. George P1ke, District Chief, Principal Investigator,  USDI, Geol. Surv.,
      Federal  Bldg. 21, P.O.  Box 1696, Helena,  Montana  59601

      Les Sprenger, Project  Supervisor, EPA,  Reg. VIII, 1360 Lincoln, Denver,  CO 80203
    NAME AND ADDRESS OF APPLICANT INSTITUTION
      Les Sprenger, Surveillance and Analysis Division
      U.S. Environmental  Protection Agency,  1860 Lincoln,  Denver, Colorado   80203
    SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach. (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
       In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
    porting research and are forwarded to investigators who request such information.  Your summary is to be used for these purposes.
           Die USGS, HRD,  Montana District  Office will collect and analyze  surface
      water  quality data  at  the six  stations  listed below:
           1.  Middle Fork Poplar River   Mr. Scohey
           2.  East Fork Poplar River    Mr. Scobey
           3.  Middle Fork Poplar River 9 International Boundary
           4.  West Fork Poplar River @ International  Boundary
           5.  Uest Fork Poplar River near Bredette
           6.  Poplar River above West Fork
      For the parameters  of:
           Parameter Group   Specific Parameters
           Field          Streamflow, pH, temperature,  turbidity, dissolved  oxygen  and
                           specific conductance
           Chemical       Calcium, magnesium,  sodium,  potassium, faacarbonate, carbonate,
                           sulfate, chloride, fluoride,  boron,  silica, and iron
           Hutrients      Total nitrite and  nitrate, total  phosphorus, total  kjeldahl,
                           nitrogen, and total  ammonia.
           Metals         Dissolved  (aluminum, arsenic, beryllium,  cadmium,  chromium,
                           chopper, lead,  mercury, maganese, nickel, and  zinc).
    IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
    dental, etc.)
                                             SIGNATURE OF PRINCIPAL INVESTIGATOR
                                          FOR OFFICE USE ONLY
       SUPPORT METHOD (Check one)
        RESEARCH GRANT
 Funds Estimate^
   [$3,650
                                PROJECT OFFICER
                                 Cooper H.  Wayman
                                                   RESPONSIBLE ORGANIZATION

                                                    EPA  - Region VIII
76
       NO. OF FUTURE YEARS TENTATIVELY
       ASSURED BEYOND CURRENT F.Y.
                                         June 1,  1976
June  30,  1977
*FundS approximate tlOt for Citation. .66 ANO SI-S.E 76. WHICH MAY NOT BE USED.
                                                  297

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                           Form Appfoi'fJ
                                                                         OMD No. D8-R008I
                                                                PROJECT HO. (Do oat uao IMm tpmcfl

                                                                SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                     CSE
TITLE OF PROJECT
  Definition of the Radon-222 Source Terra from Uranium Mill Wastes
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCASED IN THE PROJECT.
   Mr. Donald W. Hendrlcks, Director
   Dr. Robert F. Kaufmann
   Mr. Richard L. Douglas
   Mr. David E. Bernhardt
                                      Mr. Joseph M. Hans,  Jr.
                                      Mr. Fred  B. Johns
NAME AND ADDRESS OF APPLICANT INSTITUTION
                         Office of  Radiation Programs, Las Vegas  Facility
                         P.O. Box 15027              Telephone:  (702)  736-2969 Ext. 305
                         Las Vegas.  HV  89114	FTS;  SQS-296q	
SUMMARY OF PROPOSED WORK - (1) Obj.cllv.j, (2) Approach, (3) Current Plant ind/or Pro(res» (200 word! or leae. Omit conddenllat data).
   In the Smithsonian Science Information Exchange, aucnmariea of work in proereaa ara exchanged with government and private agenciea sup-
porting reaearch and are forwarded to investigators who request auch information. Your eununary ia to be usad for theaa purposes.

  A series  of technical  reports will be prepared summarizing the  interrelations among
  radium  content, moisture, and radon exhalation from mill tailings piles  in a
  variety of climatological settings typical of pertinent areas In the United States.
  Principal thrusts  include:

  1.  Extending the  data base of  spot, one-time radon exhalation  measurements.

  2.  Examining the  feasibility and demonstrating the use of digital modeling
      techniques to  calculate the moisture flux In a variety of tailings piles.

  3.  Developing 1 and 2 in conjunction with climatological studies for  subsequent
      input to airborne  dispersion  models.

  4.  Developing an  improved method of calculating the radon source term and dose
  assessment in connection with mill wastes.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED fModical.
dental, etc.)
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                                  10/8/76
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD fClioc*
                                                PROJECT OFFICER
                                                  Donald W.  Hendricks
                                                RESPONSIBLE ORGANIZATION
                                                 EPA,  Region VIII
FUNDS OBLIGATED

 $60,000
76
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
   None
STARTING DATE

April 1974
ESTIMATED COMPLETION
DATE
September 1977
EPA Foitn 57o(M (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                            298

-------
                U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
                                                                                Form Approved
                                                                               OMB No. 118-R0081
                                             PROJECT NO. (Do not use this space)

                                             SSIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          CSF
 Surface Goal Nine Report
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
 John  E. Hardaway, Chief, Research & Applications  Branch
NAME AND ADDRESS OF APPLICANT INSTITUTION
 EPA,  Region VIII
 1850  Lincoln Street
 uenver, Colorado  80203
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies aup~
porting research and are forwarded to Investigators who request such information. Your summary is to be uaed for these purposes.


 A report showing aerial photography of existing surface  mines  1n the NorthernGGreat
 Plains region  Is published.   Data  on each mine and  a discussion of the characteristics
 of  surface mines as  well as  the  technique of aerial  photography is presented.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.
dental, etc.)
                                             SIGNATURE OF PRINCIPAL INVESTIGATOR
                                          FOR OFFICE USE ONLY
    SUPPORT METHOD (Check one)
    RESEARCH GHAN '
                                      1A
                                                    PROJECT OFFICER
                                                    RESPONSIBLE ORGANIZATION
                                                    EPA Region VIII, Denver
FUNDS OBLIGATED
    40 K
                 F.Y.

                 76
NO. OF FUTURE YEARS TENTATU
ASSURED BEYOND CURRENT F.Y.
                                                               STARTING DATE
                                            6/76
4/77
EPA Form 570
-------
                 U.S. ENVIRONMENTAL PROTECTION AGENCY
                  NOTICE OF RESEARCH PROJECT
                                                                               Form Approved
                                                                             OMB No.  118-R0081
                                                                    PROJECT NO. (Do not ua-s thtm space;

                                                                    SSIE
                                                                    IPA-
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                      CSF
  TITLE OF PROJECT
  Survey of Figitive Just  from Coal  Strip Mines
  GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
  PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
  NAME AND ADDRESS OF APPLICANT INSTITUTION
  SUMMARY OF PROPOSED WORK -  (I) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less.  Omit confidential data).
    In the Smithsonian Science Information Exchange, summaries of work In progress are exchanged with government and private agencies sup-
  porting research and are forwarded to investigators who request such Information. Your summary is to be used for these purposes.

  There has  baen  little effort to  date to determine the participate Missions from a
  strip coal  mine in the arid west.   These emissions  are significant,  come from various
  points in  the mining activity, and are estremely difficult to quantify.

  This effort will  entail a detailed site specific ambient monitoring program.   Emissions
  will be  estimated by use  of a Gaussian diffusion model and the air quality and
  meteorological  data collected.
  IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
  dental, etc.)
                                             SIGNATURE OF PRINCIPAL INVESTIGATOR
                                          FOR OFFICE USE ONLY
     SUPPORT METHOD fChecft one)
                                                    PROJECT OFFICER
                                                     Cooper H.  Wayman
                                                    RESPONSIBLE ORGANIZATION
                                                     EPA Region  VIII
Funds Estimate*
  I $125,000
                  76
STARTING DATE
June  1,  1976
ESTIMATED COMPLETION
.notary  1,  197
Funds approximate not for citatiOH.es ANDSI-SIETCA WHICH MAY NOT SE USED.
                                                300

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
   TITLE OF PROJECT
     Effect of Oil on Tundra Thaw Ponds
                                                               Fur™ /Ifiproi-ej
                                                             OMB ,Vt>. H8-ROOS1
                                                     PROJECT NO. (Do

                                                     SSIE
                                                       EPA-IAG-D6-E681-BCA
  GIVE NAMES. DEPARTMENTS; AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
  PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

    John E. Hobbie,  Ecosystem Center,  Senior Scientist, 1/6 man-yr
    Stanley I. Dodson,  Dept. of Zoology, Assoc.  Prof., Univ. Wisconsin,1/12
      man-yr
    .Tames F. Haney,  Dept.  of Zoology,  Aast.  Prof. Untv. N.H., 1/9 man-yr
              Hangy,  Ttept
               OF APPLICANT TNS
   NAME AND ADDRESS OF APP^fCANT TNST1TUTION
     Marine  Biological Laboratory
     Woods Hole,  Massachusetts, 02543
   SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach. (31 Current Plans and/or Progress (200 words or less. Omit confidential data).


   Objective:
              The  research will provide  information on the effects of spills
  of crude oil  on  shallow thaw ponds  in  arctic Alaska.  Both immediate and
  long-range effects will be measured.
  Scientific Background For Study; Some  information is available on the lethj
 effects  of  oil on freshwater  plants and animals.  Practically nothing  is
 known  of effects on a pond community where indirect effects, such as the re(-
 noval  of grazing pressure on  plankton,  will occur.  Only a  few  tests have
 :>een made of sub-lethal effects  such as reduction of reproduction rate.
 Nothing  is  known of oil effects  on  arctic ponds.
 Proposed Procedure:  A follow-up study will be made of an oil spill made in
 1970 at  Barrow, Alaska.  Also, a new spill was made in 1975, and a  series o)f
 small  subponds of various sizes  have also been treated.  The amount of oil
 remaining in various fractions will be measured.  The species composition,
  bundance,  and productivity of phytoplankton, zooplankton,  benthic animals,
 and bacteria will be followed.   Also, the effect of oil on  the  growth  of
 Sarex  aouatilis. a rooted aquatic plant, will be measured as well as the
   degradation rate of Carex litter with and without oil  treatment
   Best Objects and Agents:  The objects will be natural thaw  ponds near Barrow
   Ma ska.   Crude oil from  Prudhoe Bay will be the agent  tested.
   Results  to Date: The biota  has almost completely recovered from the oil spilll
   of  1970.   The zooplankton are almost back to normal, but  one group of benthic
   animals,  Tanvtarsus  (Chironominae) are still absent.  Zooplankton are the
   nost  sensitive organisms  while the phvtoglan^ton ar^
                                       KTURE OF PRINCIPAL INVESTIGATOR
                                       John E. Bobbie
                                                                26 Feb. 1976
                                  FOR OFFICE USE ONLY
     SUPPORT METHOD '.Check one;
 Funds Estimate*
      ,000
funds I
 |$70.(
76
                                          PROJECT OFFICER
                                          Clayton M. White
                                          ERDA
     NO. OF F'JTURE, YEARS TENTATIVELY
     ASSURED eEYCNO CURRENT F.Y,
STARTING DATE

April 1976
ESTIMATED COMPLETION
DATE
 April 1978
*Funds approximate not for citation/
                                            CH MAY NOT BE USED.
                                      301

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAK SCIENCE INFORMATION EXCHANGE
                                                                         Form Approved
                                                                       OMB No. I58-R0081
                                                              PROJECT HO. {Do ml u<« ihle space;

                                                              SSIE
                                                                  EPA-IA6-D&-E681- BCA
TITLE OF PROJECT
              Suspended Sediments and Related Lissnology of  an alpine lake system
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
    Principal Investigator  .. Dr. Vera Alexander, Professor,  University of Alaska*
    Onher professional personnel ... Dr. R.J.  Barsdate, Professor, Univ. of Alaska
                                       Mr. J.C.  Mallor, Haval Arctic Res. Lab.,. 0. of A.
                                       Dr. H.W.  Denner, Director, KARL, Univ. of Alaska
                                      479-
                                   Institute of Marine Science,
                                   University of Alaska
                                   Fairbanks, Alaska 99701
SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach, (3) Currant Plans end/or Progress (200 word* or tain. Omit confidential data).
  In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary Is to be used for these purposes.
      The  aia of this project Is to assess  sediment lapact  on  arctic freshwater
      ecosystems,  using as a natnral labortaory  Lakes Peters and Schroder In the
      Brooks Range to determine the utility of aerial assessment of sedfaent
      loads.  These lakes exhibit a natural  sedlaent load gradient since turbid
      water enters lake Peters and flows through the system.   Two field seasons
      have now been completed, with a detailed asaesmant of gradient photography
      currently underway.  We also studied  sons  aspects of  the lake chemistry and
      productivity in order  to dellnleate possible Impact of alterations in
      sediment load regime on arctic lakes  In  general. Hlcrodensity techniques
      are  being used on the  film, and ground truth data are being evaluated.
      We also selected three additional lakes  along the Trans-Alaska Pipeline
      corridor for photography, and are currently evaluating these results
      also.  This project relates closely to a  separate study OB the effects  of
      the  pipeline road on freshwater environments,  and the two studies Till
      essentially merge in their objectives during the last field season.
   Research  InstlttttSe-InstltUte Of
  	Marine Science	
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
   SUPPORT METHOD (
FUNDS OBLIGATED
     38
76
                                      FOR OFFICE USE ONLY
                                  3.1  &  3.2
                                               PROJECT OFFICER
                                                 Clavton White
                                               RESPONSIBLE ORGANIZATION
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
                                               Division of Bloroedlcal & Environmental
                                                            USERDA	

6/1/75
4/78
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                          302

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE

TITLE OF PROJECT                           	
                                                                        Form Approved
                                                                       OMB No.  U8-R0081
                                              PROJECT NO. (Do not use thlm apace.!

                                              SSIE
                                              EPA	
                                              EPA-IAG-D6-E681- BCA
 Effects of Roari fimgrrTjction Ppoa Neraby Lakes  in tfaeMMknn North S3 cm
 IVE NAMES. DEPARTMENTS, AND OFFICIAlTTITtESVFTiRTiraPALTNIVESTIGATORS OR PROJECT DIRECTORS
 ilVE NAMES. DEPARTMENTS, AND OFFICIAL TIT^ESTOF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
  Principal Investigator ...Dr.  Vera Alexander,  Professor, University of Alaska*
  Other Senior Personnel ... Dr. Michael C. Miller.Aesoc. Prof. Univ. Cincinnati
                              Dr. John H. Millar, North Carolina State University
                              Dr. R.J. Barsdate,  Professor, University of Alaska
  •Institute  of Marine Science;   (907) 479-7210	
NAME AND ADDRESS OF APPLICANT INSTITUTION
   Institute  of Marina Science,
  University  of Alaska,
  Fairbanks.  Alaska 99701
SUMMARY OF PROPOSED WORK - (!) Objectives, (2) Approach. (3) Current PUn> and/or Progress (200 words or leu. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary Is to be used for these purposes.

  The study is designed to determine the effects of road construction  on lakes in
  northern Alaska, and is  carried oat along the new road associated with the
  Trams-Alaska Pipeline.   This road has altered drainage patterns  and  thus
  caused the  formation of  new lakes, and has  altered the sediment  patterns.
  The effects of road dost and other atmospheric partlcolatea as veil  as nutrient
  loading are being studied,  all with respect to lattitudinal grsndient.  Hew
  bodies of water are being monitored with tlae to  observe succession in water
  chemistry and  biota.  The effects of nutrient Input are being studied
  in situ and with bloassay approaches.   We  expect to carry out one more
  field season on this work,  having completed two to date.   Additional work
  on determining the mineral  and nutrient additions by dustfall and icefog
  will be carried out during  the winter season, some of this information to
  be gained by using snow  cores in early spring to  give an integrated  record of
  deposition.   This information, along with  suoner experimental work, should
  help give an idea of the impact from such sources.  New pond succession will
  continue to be a major focus of the work, and this work will intensify. Finally,
  the assesnent  of natural variations with latitude will be needed to  separate
  normal gradients and the effects of the human activity.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED Wctiicul,
"1&£rch institut^- Institute of
    Marlne Science	
                                         SIGNATURE OF PRINC
                         SIGN


                          I).
CU,U
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD fC/iccfc om-)
    RESEARCH GRANT
                             TASK NO.

                               3.3
                               PROJECT OFFICER
                               Clayton Unite
                                               RESPONSIBLE ORGANIZATION
                                               Division of Blomedlcal &  Environmental
FUNDS OBLIGATED
      40
76
      NO. OF FUTURE YEARS TENTATIVELY
      ASSURED BEYOND CURRENT F.Y.

                               1
                                                          6/1/75
     4/78
6PA Form 5740-1 (7-72)    REPLACES PUS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                          303

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         F<>rnt Apprni C(i
                                                                         .lin No.
                                                               PROJECT NO. (Do not u»e thin space)

                                                               SSIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                               EPA-IAG-D6-E681-BCC
TRACE METAL CYCLING § EFFECTS ON TERRESTRIAL  ECOSYSTEMS IN THE SOUTHEASTERN UNITED STATS
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED^N THE PROJECT.
J. H. Horton
     EED
Staff Chemist
NAME AND ADDRESS OF APPLICANT INSTITUTION

Savannah  River Laboratory, Aiken,  SC 29801
SUMMARY OP PROPOSED WORK -  (l) Ohj*-''t ivcs, (2) Approach. (3) Current Plans and/or Progress (200 w->rd» or les».  Omit confidential data).
parting rr Krsirch nnc1 are (orwordfd to invrst igatora who re q Meat such information.  Your summery Is to be u§«d for th«*c purposes.

The objectives are to  develop new and improved information  on  the trace metal
content of coal, ash,  fly  ash, soil,  vegetation,  etc., as a basis for evaluating
the cycling mechanisms for trace metals and  to develop means of reclaiming
abandoned ash basins.  A study is in progress  to  determine  the effect upon
the terrestrial environment of trace elements  released from a  coal fired
powerhouse  from 1952 through 1975.  Analyses of surrounding soil  and vegetation
are not complete but from  results to-date  the  effects appear to be small.
Stands of loblolly pine, sweetgum and sycamore trees have been successfully
established on an ash basin abandoned in 1964.  Survival and growth of the
trees  are better on the ashes than on soil, possibly due to a  higher water
content of  the ashes during a severe  drought.

During FY-77 analyses of the soil and vegetation will be completed.
Groundwater and biological  specimens  will be analyzed for trace metals.
 DENTIFY PROFESSIONAL SCHOOL INVOLVED {Mrilic.il,
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                           DATE

                                                                            10/6/76
                                      FOR OF/4/CE'uSE ONLY
   SUPOORT METHOD (Clu; 1 ,,.,. I
 $130,000
1976
                                               'ROJECT OFFICER
                                                David Ballantine
                                               RESPONSIBLE ORGANIZATION

                                                ERDA
                      ASSURED BEYOND CURRENT F.Y.
                           STARTING DATE


                            June 23.  1975
                                                                           ESTIMATED COMPLETION
                                                                           DATE
EPA Fnrr* 5760-t (7-7?)
                                        304

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                      ovn NO. iis-Roost
                                                             PROJECT NO. (Da
                                                             SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                             EPA	
                                                             EPA-IAG-D6-E681-BCC
Coal Ash  Contaminants in Southeastern Aquatic Systems
  'E NAMES. DEPARTMENTS. AND OFFICTAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT OIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

Michael  H.  Smith, Director
John P.  Giesy,  Research Associate
NAME AND ADDRESS OF APPLICANT INSTITUTION
Savannah  River Ecology Laboratory
Drawer E
Aiken, SC  29301
SUMMARY OF PROPOSED WORK - (I) objrrt i yr,. 12] Approoch. (3) Current Plans and/or Progress (300 word, or less. Omit confidential dan
porting rr search Hnd ure forwarded lo investigators who request such Information. Your summary la to be uaed for these purposes.
Trace contaminants from coal combustion include a number of toxic elements  which
are known to be concentrated by  aquatic biota.  Since the majority of  the electri-
cal power generated in states  such  as South Carolina is by coal combustion,  large
inputs of trace contaminants will be expected as a consequence of rapid population
growth in the  southeastern United States and projected increased dependence on
fossil fuels.   This area of the  country may experience more problems with coal ash
contaminants than other areas  because of the generally higher availability  of  these
elements in soft acid waters.  The  objective of these studies is to 1) determine
if aerial and  effluents from coal combustion increase levels of toxic  elements in
aquatic  systems adjacent to power production facilities and 2) determine pathways
and compartmentalization of trace contaminant flaxes in aquatic systems.  Aerial
inputs into a  softwater pond are being  monitored.  Elemental ratios are used to
determine if trace element inputs are from coal combustion or natural  particulate
inputs.   Cycling of metals to  all components of this low ionic strength, highly
organic  acid aquatic system has  been determined.  The hypothesis that  aquatic
systems  act as sinks for metals  and that metals bound to organics are  mobilized
from the drainage basin to the pond is  being tested.  Monitoring of aerial  inputs
is also  being  used to determine  if  electrostatic precipitators is capable of
reducing trace metal inputs into this aquatic system.   The second phase of  this
set of investigations is the fate of trace  contaminants associated with coal in
a swamp  system.   Areas receiving coal ash is being compared to central areas and
trophic  transfers water - periphyton -'  macroinvertebrates - fish are being
conducted.
IDENTIFY PROFESSIONAL SCHOOL INVOLVEO (Mritir.il,
di-rili,l. i'F.-.l
                                        SIGNATURE O5i PRINCIPAL/INVBSTIGATOR
                                                                          DATE

                                                                            10/12/76
                                      FOR OFFICE USE ONLY
FUNDS OBLIGATED  F.Y.    NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
$120,000       1976
                     zd	
                                              PROJECT OFFICER
                                                David Ballantine
                                              RESPONSIBLE ORGANIZATION
                                                ERDA
                                                       STARTING DATE
                                                       June 1975
                                                                               1978
£PA Farm 5760-1 (7-72)
                                        305

-------
U.S. ENVIRONMENTAL PROTECTION AGENCY
NOTICE OF RESEARCH PROJECT
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
Form Approved
O.M8 No. 1J3-R0081
PROJECT NO. (Da not u»e tfil» ipecel
SSIE
EPA-IAG-D6-E681-BCC
TITLE OF PROJECT
"Ecological Fate and Effects of Trace  Elements from Coal Utilization in The Semi-arid We
SIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
LaMar  J.  Johnson,  Group  Leader; David  R. Dreesen,  Ernest S. Gla^ney, Lawrence  E.  Wangen,
Caroline  L. Wienke staff members
Subcontract to Arizona State University-Thomas H.  Nash III, Miltor R. Sommerfeld
MAMS AND AD3SESS OF APPLICANT INSTITUTION
Los Alamos Scientific  Laboratory
P.O. Bos 1663
Los ils=os, SM  87545
   MA=!V C~ s^3=»OSSD 'aaa* - (1) Objectives, (2) Approach. (3) Current Plant aad/or Progress (200 word* or less. Omit confidential data).
   Ja i±* c=^;is±=tian Scier.ce L-u'?rmtian Exchange. , ---- aries of work in progresa are exchanged with government and prlvata agencies aup-
      search ai^ arc forwarded to investigator! vha request such in/oraation. Yot7 suBunary Is to bs usvd (or these purpoae*.
      The purpose of  this research is to determine the ecological fate of trace elements
resulting from the combustion of  coal in semi-arid environments of the western United
States.   The mobilization of trace elements through stack emissions and coal  ash dis-
posal are to be investigated.  Current plans call for the analysis of ambient partieu-
late  matter for trace element content as a function of particle size.  Soils  and veg-
etation  are to be analyzed to ascertain the extent of trace  element content due to
deposition on surfaces and uptake from soils and water.  The use of lichens as bio-
indicators of trace  element pollution is being  investigated.   The adaptation  of
microbial populations to metals is being investigated.
IDENTIFY PROFESSIONAL SCHOOL INVOLVES 'V*2ic^,
J-;.-irol, crc.J
Health Division-Environmental Studies
SIGNATURE OF PRINCIPAL INVESTIGATOR
> f
DATE
///////tf
1 FOR OFFICE USE ONLY
[ SUPPORT METH03 'Ch...f.
I
C

c,n,,
AGENCY STArTFr/!l,fJ~I.r«>;j


Funds Estimate
$105.000
*V.
76

TASK NO.
3
PROJECT OFFICER
David S. Ballantlne
RESPONSIBLE ORGANIZATION
ERDA
so. OF FUTURE YSAPS TENTATIVELY
ASSUHEO BEYOND CURRENT F.Y.
STARTING DATE
ESTIMATED COMPLETION
3fufy 1976
 Funds approximate not for citation.  AND SI-SIE ?SA WHICH MAY NOT BE USED.
                                               306

-------
                  U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
         PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
     -LE OF PROJECT
    Dynamics of trace elements in desert environments
                                                                            Form Approved
                                                                          OMB No. 158-R0081
               PROJECT NO. fDo not use this space)

               SSIE
               EPA	
               EPA-IAG-D6-681-BCC
   GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
   PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
    Frederick B. Turner, Ph.D.   LNMRB
    Arthur Wallace,  Ph.D.        LNMRB
    Wade L. Berry, Ph.D.         LNMRB
    Carl L. Strojan, Ph.D.       LNMRB
Research Biologist           (213)  8258773
Research Plant Physiologist  (213)  8253664
Specialist                    (213)  8258774
Postdoctoral Scholar         (213)  8258773
    NAME AND ADDRESS OF APPLICANT INSTITUTION
    Laboratory of  Nuclear Medicine  and Radiation Biology,  University of California,
    Los Angeles, California 90024
    SUMMARY OF PROPOSED WORK - (I) Objective*. (21 Approach. (3) Current Plans and/or Progress (200 word, or l.as.  Omit confidential data).
      In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
    porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.
          The combustion of coal releases potentially toxic elements into the atmosphere.
     These are ultimately deposited  on vegetation or  the ground and incorporated into
     biogeochemical  cycles.  The purpose of this research is to determine natural
     storages and pathways and rates  of transfer of trace elements (e.g., Cd, Ni, Cu,
     Co, Pb, Zn)  in  and between components of desert  environments.  Potential sites of
     accumulation will be identified.  Field work is  being carried out  in southern
     Nevada—in the  vicinity of Southern California Edison's Mohave Generating Station,
     and at the Nevada Test Site.  Experiments are conducted at the University of
     California,  Los  Angeles.  Amounts of trace elements in desert vegetation are being
     analyzed by  emission spectroscopy.  Trace elements  in soils and animals  are being
     measured by  atomic absorption spectroscopy.  Biological storages of elements are
     estimated by combining chemical  analyses of plant and animal tissues with biomass
     estimates of desert populations.  Greenhouse experiments with desert shrubs and
     soils amended with coal fly ash  are designed to  measure rates of uptake  of trace
     elements, and how such elements  are distributed  in  various plant tissues.  Field
     experiments  are in progress to  determine rates at which plant litter decomposes and
     returns elements to the soil.
    IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
    dental, etc.)
                                            SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                    ''u<. k
                            DATE

                            Oct.  22, 1976
                                          FOR OFFICE USE ONLY
       SUPPORT METHOD (Chsck i
Funds Estimate"
   $130, 000
~.Y.

 76
                                                   PROJECT OFFICER
                                                   David S. Ballantine
                                                   RESPONSIBLE ORGANIZATION
                                                   ERDA
                         NO. OF FUTURE YEARS TENTATIVELY
                         ASSURED BEYOND CURRENT F.Y.
        STARTING DATE

          1976
                                                                              July 1977
*Tunds approximate not for citation. * ANDS.-S.E 76A WHICH MAY NOT ,
                                               307

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OP RESEARCH PROJECT
                                                                        OMB \a.
                                                               PROJECT NO. (Do fujl us* thin tpacfi
                                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                EPA-IAG-D6-E681-BCC
 TITLE or PROJECT Envir0nmentai Impact of Coal Ash on Tributary Streams and Nearshore Waters
:>n Lake Erie	
"LlVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS Oft PROJECT DIRECTORS AND ALL OTHER
 PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Dr. Kenneth G. Wood,  Biology Dept.,  State University College, Fredonia,  New York 14063
Dr. David Dingledy,  Dept.  of Shemistry, SUC at Fredoniai  Dr. Robert Fahnestock,  Dept.
   Geology,  SUC at Fredonia^ Dr. Walther  Barnard,  Dept. of Geology,  SUC at Fredonia;
Dr. Donal Crowley, Dept,  of Geology,  STTC at Frgdcmia	.	.	.
 NAME AND ADDRESS OF APPLICANT INSTITUTION
 '.tate University College,  Fredonia,  New York 14063
 SUMMARY OF PROPOSED WORK - (1) Ob;i-clivfH"
' L". C'i COL

$100 K
                 76
                             TASK NO.

                                  5
                                               PROJECT OFFICER
                                                David  S.  Ballantine
                                                RESPONSIBLE ORGANIZATION
                                                  ERDA
                      ^O. 0^ ruTuPf YEAR? TE'JT UTiv
                      ASSUHE.D DE-tONO CURRENT F.Y.
r.STIMATelC CO.V
DATE
      9/77
 EPA Form 57CO-1 (7-72)    RCPLACFS PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT 9C USED.
                                            308

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                    PROJECT NO. f

                                                    SSIE
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
   riTLE OF PROJECT
                                                       EPA-IAG-D6-E681-BCC
 1 i i uc. i_*r r-rvjjc.*~. i                                  	

Ihe Contamination of Groundwater by Heavy Metals from the Land Disposal of
 GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL IN VEST1G ATO flS OR PROJECT DIRECTORS AND ALL $THFRAsh
 PROFESSION Al. PPRSnHMFI p-wnA^ET-i IM -rue naf\ic?r-r                                       * J   w*«
   GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL IN VEST1G ATOflS OR PROJECT DIRECTORS AN O ALL
   PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.

   Dr. Thomas L. Theis - Assistant Professor  of  Civil Engineering 0.3 man-years
   Dr. Jerry J. Marley - Associate Professor  of  Civil Engineering o.!6 man-years
   NAME AND ADDRESS OF APPLICANT INSTITUTION
    Graduate School  (University of Notre Dame)
   Department of Civil Engineering. Notre Dame,  Indiana 46556
   SUMMARY OF PROPOSED WORK- (I) Objectives. (2) Approach. (3) Current Plans and/or Prof»» (200 u/ords or less. Omil confLdenlia 1 ij
        The objective  of the proposed work  is  to define the aqueous chemistry
   of heavy metals associated with fly ash  disposal systems.  It has been
   demonstrated  that many heavy and trace metals are concentrated on fly ash
   during the coal combustion process.  Normal disposal practice for this
   naterial involves ponding or use directly as fill.   Considering the amounts
   which must be disposed of (1975 estimate, 30-35 million tons), a potential
   contamination problem exists with local  groundwaters.
        Previous research conducted on this problem in the first year of stud]/
   involved laboratory experiments in which the sorptive characteristics of the
   species As, Cd, Cr, Cu, Fe, Hg, Mn, Pb,  and Zn associated with these systetrs
   was investigated.   The coming year's effort will continue with these labora
   tory studies,  however the main emphasis  will be on field research on exist-
   ing disposal  sites.  The procedures to be used will include monitoring
   through a well survey and a heavy metal  tracer study using either a radio-
    ctive or inorganic source of the metals of interest.  Laboratory data will
   t>e coordinated through a mathematical groundwater quality model to predict
   metal attenuation with distance from source.  The model will be calibrated
   with laboratory leaching columns and through comparison with field data.
   RESULTS TO DATE;  Suggest that release of metals from fly ash in aqueous
   environments  is  dependent upon the presence,  sorptive characteristics and
   concentration of various metal "sinks" associated with the ash (e.g.Fe(CH)3
   Mn02, etc).   Subsequent readsorption  onto local soil matter is strongly pH
   dependent and is also a function of "sink" presence and concentration.
   IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical t
   JcfU.i/, etc.)
                                     SIGNATURE OF PRINCIPAL INVESTIGATOR
                                     Thomas L.  The is
                                                              2/17/76
                                   FOR OFFICE USE ONLY
      SUPPORT METHOD fCh,"c« wm-)
    XJ";
         l' ARCH GRANT
 Funds Estimate*' F-Y-~
   fcioo.ooo
              76
                                          PROJECT OFFICER
                                          David S.  Ballantine
                                          RESPONSIBLE ORGANIZATION
                                          ERDA
                  NO. OF FUTURE YEARS TENTATIVELY
                  ASSURED BEYOND CURRENT F.Y.
                                                  STARTING DATE
                                                                  ESTIMATED COWPLE-1CN
July 1976
*Funds approximate not for citation. 16C AND S'-5IE 76A "HICH HAY f'OT 8E U3E
                                      309

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                Form Approved
                                                              OMB No. S58-R0081
                                                       PROJECT NO. (Do nut use this space)

                                                       SSIE
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                     EPA-IAG-D6-E681-BCC
                Development  of Biological  Indices for Identifying & Evalua-
   TITLE OF
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
John Cairns,  Jr., Univ. Distinguished Prof,  of Zoology, Biology Dept., VPI6
Ernest F.  Benfield, Ass't  Prof,  of Zoology,  Biology Dept.,  VPI&SU
Arthur L.  Buikema,    "     "    "     "         "     "         "
                                                                                  SU
   NAME AND ADDRESS OF APPLICANT INSTITUTION
  Dept.  of Biology & Center for Environmental Studies
  1020 Derring Hall
  Virginia Polytechnic  Institute &  State University. Blaeksbtire.
                                                                   Va. 2&Q61
   SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
     In Ihe Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
       Structural responses of aquatic communities to pollutional stresses ha
  listorically  been the principal methods by which biological assessment of
  mvironmental perturbations have been evaluated.  While community structure
  responses are often of value,  they do not give  the investigator sufficient
  information to understand the  impact of stresses on community  dynamics, e.g
  energetics and nutrient cycling.
       The primary objective of  this work is to examine a number of major
   functional processes common to most aquatic communities in terms of develo
  Lng and evaluating techniques  for measurement of those processes in terms
  Df their suitability for pollutional stress assessment.  A secondary objec-
  :ive of the work will be an attempt to relate data generated by examining
  functional aspects of communities with standard community structure measure
  nents.
       The general areas to be examined in the project include the following:
  L) evaluation of functional indices to assess pollution effects on autotrop
  md heterotrophic communities; 2) relationship  of protozoan invasion and ex
  :inction rates to the eutrophication process; 3) responses of  zooplankton
  subjected to  cooling water entrainment; and 4)  responses of detrital proces
  ing to pollutional stress.  The research has been ongoing for  approximately
  nine months and significant progress has been made in all areas of study.
                                                                                ic
   1OENTIFY PROFESSIONAL SCHOOL INVOLVED OT
                                    SIGNATURE OF PRINCIPAL INVESTIGATOR
                                      John Cairns,  Jr.
                                                                DATE

                                                                2/24/76
                                  FOR OFFICE USE ONLY
     SUPPORT METHOD fOjecfr onej
Funds Estimate* f
  {$100,000
             76
                                          PROJECT OFFICER
                                          David  S.  Ballantine
                                          RESPONSIBLE ORGANIZATION
                                          ERDA
                    NO. OF FUTURE YEARS TENTATIVELY
                    ASSURED SEYOND CURRENT F.Y.
                                                 STARTING DATE
ESTIMATED COMPLETION
DATE
 July 1976
      approximate not for Citation, i&s AND SI-SIE ?SA WHICH MAY NOT BE USED.
                                      310

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                  U.S. ENVIRONMENTAL PROTECTION AGENCY
                   NOTICE OF RESEARCH PROJECT
                                                                            Form Approved
                                                                          OMB No. nS-ROOSl
               PROJECT NO. (Do not u«« thlt apacej

               SSIE
         PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
               EPA

                EPA-IAG-I&-E681-QCC
          Numeric  Information
     IVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
     ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
          R. L.  Burgess
          R. H.  Strand and R.  3.  Oi&on
          Environmental Sciences  Division
    NAME ANO AODRESS OF APPLICANT INSTITUTION
          Oak Ridge National Laboratory
          P.O.  Boa X
          Oak Ridae. TN  37830
    	UO.K tfT-Oge. TiV  C/Q3U	
    1UMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or If mm.  Omit confidential data).
      In the Smithsoninn Science Information Exchange, summaries of work in progress are exchanged with government and private agencies mup-
    lorling ri-strarch and ure forwarded In investigator* who request such information. Your summary la to be used for these purpose «,
    Objectives - The overall objective is to provide numeric information processing and
    analysis support for the assessment and  related regional studies  being  performed  by
    the  Oak Ridge National  Laboratory for the  Environmental Protection Agency to evaluate
    the  effects of surface  mine-land reclamation activities on  freshwater resources.
    Approach - Specific needs  and approaches will be developed  through continued interaction
    with investigators.  Existing data will  be acquired, edited, documented and stored in
    the  Numeric and Textual  Information System (NUTIS)  developed by the Environmental  Sci-
    ences Division.   The Statistical Analysis  System (SAS-76) will  be used  in conjunction
    with NUTIS to provide data  management and  statistical analysis  capabilities.  Our effort
    will  be coordinated with Argonne National  Laboratory to m4nimize  duplication and
    maximize compatability  of  data bases.
    Current Plans/Progress  - We are currently  processing the USGS water quality/quantity
    tapes and have obtained air quality tapes.   We are developing  computer  files describing
    toxic compounds potentially found in  aquatic ecosystems.  These files,  derived from the
    literature, contain numeric information  in tabular form and  cover by element and  organ-
    ism  the concomnitant effects of environmental variables such as pH, hardness, alkalinity
    temperature, DO, total  dissolved solids  and  concentration of the  compound.  We have con-
    current projects that are  developing  compatible county level environmental data bases
    for  use by the EPA studies.  Computer capabilities are being expanded in the area of
    graphical display.
    IDENTIFY PROFESSIONAL SCHOOL INVOLVED r,V..rfic.J,   SIGN ATURE OF PHINC PAL INVESTIGATOR
                                          FOR OFFICE USE ONLY
       SUPPORT METHOD (Oirffc <>"'•)
Funds
    $50,000
                    76
PROJECT OFFICER
David  S. Ballanttne
                                                   RESPONSIBLE ORGANIZATION

                                                   ERDA
                          NO. OF  UTUHE YEARS TENTAT.VELY
                          ASSURED BEYOND CURRENT F.Y.
                                                            STARTING DATS
                            ESTIMATED COMPLETION
                            DATE
                                                                                      1977
•*Tunds approximate not for citation. ** «»o S.-S.E 7^ *H,CH MAY NOT BE USED.
                                               311

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
                                                             PROJECT NO. (Do not use thin apace/

                                                             SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                              EPA-IAG-D6-E77 2-BCV
 The Physiological Effects of Arsenic,  Cadmium, and Copper on Marine Shellfish
OIVE NAK'ES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

 Project Director:  David W. Engel, Ph.D., National Marine Fisheries Service
 Project Officer:  B'.A. Fowler, Ph.D., NIEHS
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Nat' 1 Institute of Environmental Health Sciences, P.O.Box 12233,  Res. Tri. Park,  N.C.
 27709
SUMMARY OF PROPOSED V.OPK - tl> Objr-ctives, (2) Approach, (3) Currcr.r Pljn
                                                     nd 'or Progress i200 word* or less,  omit confidenti*: da'.A).

      search and are forwarded te investigators *ho request such Information. Your jummary is to be used for these purposes.
     This study was undertaken to determine the physiological,  biochemical, and ultra-
 structural effects of arsenic,  cadmium,  and copper on tissues of marine shellfis h in com-
 parison with those previously observed  in mammals.  Large numbers of shellfish will be
 exposed to these elements for subsequent incorporation of freeze-dried shellfish meats
 into rat diets for evaluation of pharmacokinetic and toxicological differences in comparison
 to similar doses of these metals administered in drinking water.  At this stage,  a suitable
 sea water system has been developed for dosing of oysters with cadmium  (410 ppm) and
 copper (360 ppm)  were found in freeze-dried meats of these animals indicating a much
 faster and greater capacity for cellular accumulation of  these elements than is known to
 exist in mammals. During the next year,  glucose metabolism and oxygen consumption in  '
 similarly dosed oysters will be studied.
       PROFESSIONAL SCHOOL INVOLVED (Medici,   SIGNATURE OF PRINCIPAL INVESTIGATOR      DATE
          METHOD 'CI,,'CI< ,
JJClNCCOT^Tfcn COr.-T^ACT


' U '. C j COL1G
-------
              u.s. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                       PROJECT NO. (Da ,

                                       SSIE
     PREPARED POR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                       EPA	
                                       EPA-IAG-D6-E772-BCV
TITLE OF PROJECT        ~~~~	                  "
Metabolism of Hydrocarbon Isomers in Vertebrate and Invertebrate Marine Species
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL. INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
John R. Bend,  Ph.D.,  Head, Marine Pharmacology and Biomedicine Section, Pharmacology
Branch (Principal Investigator); Margaret O.  James, Ph.D., Marine Pharmacology and
Biomedicine Section,  Pharmacology Branch; Robert P. Weatherby,  Ph.D.,  Marine Phara-
cology and  Biomedicine Section, Pharmacology Branch
NAME AND ADDRESS OF APPLICANT INSTITUTION
Nat1 1 Institute of Environmental Health Sciences,  P.O.Box
SUMMARY OF PROPOSED V.OPK - (J) Objrrtlvci, (2) Approach. C3> Cu.-rc.il Plum nnrt.'or Ptos.ns 1.200 a-ords or learn. Omit confidcr.iu: data).

     The in vitro metabolism of selected hydrocarbons, which are constituents of crude or
 refined petroleum products, will be studied in.marine species indigenous to Florida and
 Maine.  Special attention will focus on benzo(a)pyrene, a polycyclic aromatic hydrocarbon
 associated with chemical carcinogenesis  and mutagenesis.  The enzyme systems respon-
 sible for alkene oxide and arene oxide biotransformation will also  be studied  (in vitro) in
 hepatic and extrahepatic tissues of marine species from Florida and Maine.  The effects
 of preexposure of marine animals to chemical pollutants associated with petroleum on the
 subsequent uptake, distribution,  metabolism  (in vivo and in vitro) and excretion of
 selected hydrocarbons including octane,  hexadeccane and benzo(a)pyrene will also be
 studied and compared to similar investigations in untreated animals.
       PROr'ESSIGNAL SCHOOL INVOLVED (MeJic.J,
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                     FOR OFFICE USE ONLY
   SUPPORT METHOD .'C.-u-cfc <

    ACI-'jCY STAFF fli:l,.imiiml
fUNDC CDUIGATED 1 F.Y.

  $70,000        76
      TASK NO.

            8-2
PROJECT OFFICER
 Dr. Larry G. Hart
                                              RESPONSIBLE ORGANIZATION
                                              NIEHS
NO, Or FLJ
ASSUMED
 YEAR? T E *' T A T | v
NO CUtlRENT F.Y.
    0
         STARTING DATE
             7/75
If.STIMATcC COUPLET!
°ATE1977
EPA Form 5760-1 (7-72)    RCPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT SC USED.
                                         313

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                         ¥rtrm Approved
                                                       OMB .Vo. MS-BOOS/
                                                              PROJECT NO. (Do not ua« tftfa

                                                              SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                               EPA-IAG-D6-E772-BCV
TJ,TLE OF pso-rec-Carginogenic tirects 01 Petroleum Hydrocarbons on Selected Marine and
 Esluarine Organisms
&IVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

 John R.  Bend, Ph.D., Visiting Scientist,  Pharmacology Branch
 Bruce A. Fowler, Ph.  D., Senior Staff Fellow, Environmental Toxicology Branch
NAME AND ADDRESS OF APPLICANT INSTITUTION
 National Institute of Environmental Health Sciences,  P. O.  Box 12233, Res.  Tri.  Park,
 N. C.  27709	
SUMMARY OF PROPOSED WOPK - (1) Objectives. <2> Approach. (3> Current Plans and/or Progress (200 words or less. O:ml confidential data).
   In the Smithsonian Science Information Exchange, sum.Taries of work in progress are exchanged with government and private agencies sup-
porting research and arc forwarded to investigators who request such Information. Your summary is to be used for these purposes.

    Pre-metamorphic and post-metamorphic forms of a selected flatfish species,  that has
 been demonstrated to develop epidermal papillomas,  will be exposed to ,benzo(a)pyrene
 and possibly some of its electrophilic derivatives and the incidence of papillomas in the
 exposed animals will be assessed.   Control groups will be included for each exposed
 group in the study.  The histopathology of tumors occurring in both exposed and control
 groups will be  assessed comprehensively.  Benzo(a)pyrene hydroxylase activity will be
 measured in hepatic microsomes prepared from both control and  exposed fish, with and
 without epidermal papillomas,  that  survive until sacrifice (10-12 months of age).  This
 project will be done on a  research contract. The proposals have been  ranked and those
 with the highest scores have been site visited.  An award will be made by November,  1976.
IOEUTIFY pt'.Of ESSIONAL SCHOOL INVOLVED fA/
*•«!.,/. ,.fc.l
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                      FOR OFFICE USE OMLT
   SUPPORT METHOD (Chock orit-J
   CS OBLIGATED
                               8.3
  $45,000
F.Y.
 76
                                               PROJECT OFFICER
                                                 Dr. Larry G. Hart
                                RESPONSIBLE ORGANIZATION
                                  NIEHS
                      NO. QF FUTU»E YEARS TENTATIVELY
                      ASSUHEiD QEYOND CURRENT F.Y.
                                     -0
                                                        STARTING DATE
                                             7/75
F.STIMATEO COMPLETION"
DATE
  1977
EPA Form 5740-1 (7-72)    REPLACES PHS FORM 166 ANO SI-SIE 76A WHICH MAY NOT BE USED.
                                          314

-------
             U.S. ENVIRONMENTAL PROTECTION AGENCY
              NOTICE OF RESEARCH PROJECT
                                                              Form Approved
                                                             O.MB No. 158-R0081
                                       PROJECT NO. (Da not use this

                                       5SIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE

        30JECT
  rTTo
 Envirnnmfintn1
                                         EPA-IAG-D6-E693-BEN
                             of Northern Puggt Sound  and th£ Strait  of Juan d
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
         Dr. Howard S. Harris, Project Manager
         Environmental Research Laboratories/NOAA
         3711   15th Ave.,  N.  E.             Phone:   (206)  442-0199
         Seattle, WA  98105                        FTS   399-0199
NAME AND AOORESS OF APPLICANT INSTITUTION

         NOAA

         Rockville, MD  20852
SUMMARY OF PROPOSED WORK - (I) Objective*. (2) Approach, (3) Curr.nl Plans and/or Progress (200 word, or less. Omit confidential data).
   In the Smithsonian Science bifurmation Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to b« used for these purposes.
 This project  is designed  to  provide the ecological  data required for
 making management decisions  concerning  regional development and  for
 assessing  the potential impact of petroleum hydrocarbons on the  eco-
 system.  The  results of this research will be immediately applicable
 to decisions  on the lofeation of deepwater ports, expansion of  refinery
 capacity at existing sites  verses the development of  new sites,  and the
 regulation of tanker traffic in parts of the sound.

 Investigations will be based on existing ecological and environmental
 data augmented by field and laboratory  investigations.  Priority will be
 given to evaluating the ecological  factors at risk  from the instantaneous
 release of a  large volume of oil.   Second priority  will be given to
 the ecological factors at risk from the chronic effects associated with
 transnort,  transfer, and  processing of  oil and oil  products.   Output
 products will include:   (1)  description of existing ecological and en-
 vironmental conditions,  (2)  the present occurrence  and variability of
 petroleum  related pollutants,  (3) a state-of-art oil  spill trajectory
 model for  northern Puget  Sound and  the  Strait of Juan de Fuca, and
  (4)  an ecosystem model to provide prediction of fate  and effects of
 selected pollutants on components of the marine ecosystem.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED rMrrilr.il.
 N/A
                     SIGNATURE OF PRINCIPAL INVESTIGATOR

                       Howard S.  Harris
DATE

 28 Sept. 1976
                                 FOR OFFICE USE ONLY,
   SUPPORT METHOD fCht-i-k o.i.->
 FUNDS OBLIGATED
 $920K
 S230K
76
                             1-4
                          "ROJECT OFFICER
                              John W.  Townsend.  Jr.
                                         RESPONSI3LE ORGANIZATION

                                           NOAA/ERL
    NO. OF FUTURE YEARS TENTATIVELY
    ASSURED 8EYONO CURRENT F.Y.
                                                 STARTING DATE
                                  1 Sept. 197s    1 Seot.  1980
                                                                 ESTIMATED COMPLETION
                                                                 OATE
'tPA Ferr. 5760-1 (7-72)    REPLACES PNS FORM 166 AND SI-SIE 7«A WHICH MAY NOT BE USED.
                                    315

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
                                                                        Form Approved
                                                                      OMB No.
                                                             PROJECT NO. (Do oat uee Oil* apaeej
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                               JPA-IAG-D6-E693- BEO
TITLE OF PROJECT
              Golf of Mexi
                             Assessment of an Active Oil Field In the Horthweirtern
                              1975-1980
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Or.  Joseph W. Angalovic,  Golf Coastal Fisheries Center (GCFO,  GalvMtcn, Texas,
    Project Manager.  Phone.  (713) 763-1211,  Ext. 501
Dr.  Richard J. Barry,  GCFC, Galveston, Texas, Project Coordinator,
    Phonei  (713) 765-1211,-Bit, 532
NAME ANO ADDRESS OF APPLICANT INSTITUTION
 National Marina Fisheries Service
 Golf pMafa.1 Fisheries Center
 4700 Avenue O
SUMMARY OF PROPOSED WORK - (I) Objectives, (2) Approach. (3) Current Plant and/or Proffreaa (200 words or laaa. Omit confidential data).
  In the SmilhBonian Science Infornuition Exchange, euffiaiariea of work in proe»»a-are eschanged with government and private agenclaa aup>
porting research and ure forwarded to inve»llgator» who request alien inlonnatlon.  Your aununary la to be uavd for thoae purpoaea.
     A detailed 5-year environmental assessment study of the Buccaneer oil and gas field
 vas initiated in April 1976.  The Buccaneer Field ia about 30 miles •oath of Galveston,
 Texas, and is relatively isolated trem other gam and oil wells.   It inclaaes two  pro-
 duction platform*  and 13 satellite platforms.  The field has  produced both gas and oil
 since 1963.  The objective* of the stndy ant  to describe the existing eccsyateas and
 area! distribution of their major cotaponentsj to compare the  concentrations of pollutaal s
 in the sediments,  water, and biota of  the oil field with those in an unaltered area;and
 to identify changes that have occurred.   The project is making use of historical  and
 new data to describe and quantify the  biological, chMtical, and  physical characteristic!
 and the tesporal variations of these characteristics in the envlronBents of the oil
 field and the control area.  Surveys have been <*•«•<»•»•«.* to describe the hydrography,
 water quality parameters, sediments, pollutants,  and the abundance, distribution,div
 sity and habitat of major planktonia,  benthic, and pelagic ceeannities.
 Principal Investigators;
 Mr. K. Heal Baxter, GCFC, Galveeton, Demersal Flnfishes -  AC713  763-1211, Ext. 526
 Mr. John B. Finucane, GCFC, Panama City,  Fla., Ichthyoplanleton - AC9O4 234-6541
 Dr. W. Lee Trent,  GCFC, Panama City, Fla.,  Pelagic and Beef Fish - AC9O4 234-6541
     Kick Potheringham. Oept. of Biology,  Cniv. Houston, Houston, Tex., Effects of Oil
    Field Structur
       - KC713 749-1763
             Dept. of Biophysical Science
Dr.
   ]
Dr. Brian S.
   Hydrocarbons - AC713 749-4845/2801
Dr. John B. Anderson, Dept. of Geology                              	
   Metals - AC713 527-4884
Dr. Donald E.  Harper, Dept. Mar. Sci., Texas ASM Onlv., Galveston, Tex., Benthos -
   BCfl3 744-7161, Ext. 242
Dr. E. William Behrens, Mar.Sci.Inst.,Tex.Unlv.,Pt.Aransas,  Tex., Total Organiea -
   AC512 749-6745
                                                           Dniv.  Houston, Bouston,  Tex.,

                                           Rica Inst. , Bouston, Tex., Sedimpnta and Trace
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Mcdicul,
"'National Marine Fisheries Service
 Gulf Coastal Fisheries Center
                                                                9/24/76
                                     FOR OFFICE USE ONLY
   SUPPORT METHOD (C/i.-.-t an,-)
    RESEARCH GRANT
                                 1-6
                                              PJotfnTfif.F"ifownsend, Jr.
                                              RESPONSIBLE ORGANIZATION
                                              NCAA
  176,000
Y6
76TO
                     NO. OF FUTURE YEARS TENTATIVELY
                     ASSURED BEYOND CURRENT F.Y.
                                                       STARTING DATE
                                                       1 Sept.  1975
                                                                          ESTIMATED COMPLETION
1 Sept.  1980
EPA Form 5760-T (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                          316

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                            Form Approved
                                                                          O.Mfl No. 158-ROOSl
                       PROJECT NO. (Do not ua« thlx spocej

                       SSIE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                 SFA-SAG-D6 -E72 1 -BDO
r,   IT.-  j „   Fieid & Filt/Unfilt Field Exposure Chamber Studies of the  Effects of
Coal-Fired Power Plant  Emissions  on Crop  & Forest Species of  Economic Impt. in SE US
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.                   Division  of Environmental Planning
Herbert C. Jones III (Project Director),  Supv.,        Air Quality Research Section
 Air  Quality Research Section                            Tennessee Valley Authority
Norman L. Lacasse  (Principal Invest.), Biologist       E&D Building
N.  T. Lee and  C. McDuffie, Biologists                   Muscle  Shoals, Alabama  35660
   	                                                  Phone:  FTS 872-8342
NAME AND ADDRESS OF APPLICANT INSTITUTION
Division of Environmental Planning
Air Quality Research Section
Tennessee Valley Authoritv
T*!rVn Building.  Muscle Shoals  Alabam
35660
 SUMMARY OF PROPOSED WORK- (1) Objectives. (2) Approach, (3) Current Plans and/or Progress (200 words or lees.  Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
 porting research and are forwarded to investigators who request such information. Your summary Is to be used for these purposes.

 These studies  are aimed  at characterizing  under field  conditions  the relationships  of
 pollution  dose and effects on  foliar appearance, growth, and yield of selected crop
 and  forest species (including  soybeans, wheat,  cotton,  and Virginia pine).  Both field
 plots and  field exposure chambers are being utilized  in the studies.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (,Mi-
-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                          Form A
                                                                          Vn No.
                                                                PROJECT NO. (Do not use this spucr)

                                                                SSIE
                                                               EPA
                                                               EPA-IAG-D6-E721- BDO
TITLE OF pRojEcTDose_Rasponse Kinetics for Effects of Atm.  Emissions  from Coal-Fired Pr.
Plants on Soybeans & Other Crop & Forest Sp.  of EC. Impt.  in the SE US.
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Herbert C.  Jones III (Project Director), Supv.,
 Air Quality Research Section
Norman L. Lacasse  (Principal Invest.), Biologist
N. T.  Lee,  C. McDuffie, & F. P. Weatherford,
 Biologists                               	
                                                           Division of  Environmental Planning
                                                           Air Quality  Research Section
                                                           Tennessee Valley Authority
                                                           E&D Building
                                                           Muscle Shoals,  Alabama   35660
                                                           Phone:  FTS  872-8342
NAME AND ADDRESS OF APPLICANT INSTITUTION
Division of Environmental Planning
Air Quality Research Section
Tennessee Valley Authority
F.&T) Bm* 1 H*int> . MTigrlf* Rfanalfl  Alabam
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omtt confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
The  studies involve acute and  chronic controlled exposure studies of the effects  of
S02,  N02, 03, and  combinations of these pollutants on  the growth and/or yield of
soybeans, cotton,  wheat, and Virginia pine  grown and exposed under  several environ-
mental regimes.  Responses measured include visible injury,  growth,  yield, respiration,
and  photosynthesis.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED fM
dentul, rfc.)
N/A
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                            DATE

                                                                              9/27/76
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD iClu-ck anrl
FUNO3 OBLIGATED
   45 K
               1976
                                  2.
                      MO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
                                                                                 5/6/80
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND S1-SIE 76A WHICH MAr NOT HE USED,
                                          318

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               U.S. ENVIRONMENTAL PBOTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                           Farm Approved
                                                                         OMH No.
                                                                PROJECT NO. (Do not u«e this space)
                                                                S5IE
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                S'A1AG-D6-E721-BDO
   LE OF PROJECT   Transfer,  Fate, and Effects  of SO*, SO*,  and Acid Precipitation  on a
Terrestrial Ecosystem  Representative of the  Tennessee Valley Region
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OS PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Herbert C. Jones III  (Project Director), Supv.,
 Air  Quality  Research  Section
3. M. Kelly  (Principal  Invest.),  Biologist
J.  C. Noggle,  Biologist
                                                         Division of Environmental Planning
                                                         Air Quality Research Section
                                                         Tennessee Valley Authority
                                                         E&D Building, Muscle Shoals, Ala 356
                                                         Phone:   FTS 872-8342	
NAME AND ADDRESS OF APPLICANT INSTITUTION
Division of  Environmental Planning
Air Quality  Research Section
Tennessee Valley Authority, E&O Building, Muscle Shoals, Alabama 35660
SUMMARY OF PROPOSED WORK -  (1) Objectives. (2) Approach. (3) Current Plan, and/or Progress (200 word, or less. Omit confidential dalaj.
   In thr Smithsonian Srienci- Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research iirid are forwarded to investigators who request such information. Your summary It to be used for these purposes.
The  objective of these studies  is  the characterization and quantification of the
transfer, fate, and effects of  SOX,  NOx, and  acid precipitation on  forested ecosystems
typical of the Tennessee Valley.   Field studies  include the development of sulfur and
nitrogen budgets for forested watersheds including measurements of wet  and dry atmos-
pheric input.   An acid rain simulator system  has been developed and  is  being utilized
to evaluate plant and  soil response  to various precipitation pH levels.
                                                    F PRINCIPAL INVESTIGATOR
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (.Vi-'/«-.'l.
drift.,1. i-lt-.l
                                       FOR OFFICE USE ON
                                                 RESPONSIBLE O*TO*NI Z ATION
                                                   Tennessee/Valley Authority
                                                          G/ARTING DATE         ESTIMATED COMPLETION
                                                                              DATE
FUNDS OBLIGATED  F.Y.    NO. OF F U TURE YE AOS TEN T ATIVELY
                      ASSURED BfYOND CURRENT F.Y.
    184K
                1976
EPA Form S760-1 (7-72)     REPLACES PMS FORM Ib6 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                          319

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U.S. ENVIRONMENTAL PROTECTION AGENCY
NOTICE OF RESEARCH PROJECT
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PROJECT Beneficial Effects of S02 Emissions irom C
Crop and Forest Species
Form /\f>proi'fd
O.Mfl No. I^8-R0081
PROJECT NO. (Do not ua* thia apace)
SSIE
EPA
•EWAG-D6-E721-BDO
loal-Fired Power Plants on
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT. Division of Environmental Planning
Herbert C. Jones III (Project Director), Supv., Air Quality Research Section
Air Quality Research Section Tennessee Valley Authority
J. C. Noggle (Principal Invest.), Biologist JScl^ShSf s , Alabama 35660
Phone: FTS 872-8342
NAME AND ADDRESS OF APPLICANT INSTITUTION
Division of Environmental Planning
Air Quality Research Section
Tennessee valley Authority
E&D Buildine. Muscle Shoals, Alabama 35660
SUMMARY OF PROPOSED WORK - (!) Objectives. (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
In the Smithscnian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
This study will involve the evaluation of economic benefits of sulfur deposition from
the atmosphere on crop and forest species. Techniques for measuring S02 transfer from
the atmosphere to the terrestrial ecosystem will be investigated in the vicinity of a
large coal-fired steam plant. Accumulation of sulfur in soils at various distances
from coal-fired steam plants will be measured.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED fMcdicnl. SIGNATURE OF PRINCIPAL
rfonl.il, rrc.) 	 ,
./A ^ ***&*
FOR OFFICE USE ONVT/ /
SUPPORT METHOD [Check am-) TASK NO. p^f&/af'T^
•"" — ""— " /"#t
-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
      PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                           Form Approvtd
                                                                         O.MB No, nS-ROOHl
PROJECT NO. (Do not uae Mils spacej

;sie
CPA

 2PA-IAG-D6-E721-BDP
        PHOjecT   Fate it Etrects ot Atmospheric Emissions from Cooling  Systems
                 on Terrestrial Habitats
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OB PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENOAoEo IN THE PROJECT.               Division  of Environmental Planning
 Herbert C.  Jones III  (Project Director),           Air Quality Research Section
   Supv., Air Quality Research Section               Tennessee Valley Authority

 J. M. Kelly (Principal  Invest.),  Biologist         E&D Building
 Danna Baird,  Biologist                               Muscle  Shoals, Alabama  35660
                     5                                  Phone:  FTS 872-8342
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Division of Environmental  Planning
 Air Quality Research Section
 Tennessee Valley Authority
 E&D Building. Muscle Shoals, Alabama  35660
SUMMARY OF PROPOSED *ORK - (I) Objectives. (I) Approach. (3) Currenl Plan. and/or Profress (200 wort, or less.  Omit confidential data).
   In the- Smiihsoninn Science Information Exchange, summaries at work in progress are exchanged with government and private agencies sup-
porting rest-arch and .re forwarded tr> investigators who request such information. Your summary Is to be used for these purpose!.

 This  investigation is aimed at  identifying and  characterizing the effects of atmos-

 pheric releases from mechanical and  natural  draft cooling towers.  Measurements

 include (1) wet and dry  deposition of toxic  chemicals, their  accumulation in and

 effects on soil and vegetation,  (2)  impacts  of  moisture on growth and/or yield of

 selected crop and timber species and incidence  of disease.

                                                 Tennessee Tazley  Authority
EPA Form 5760-1 (7-72)    REPLACES PUS KOWM 166 AND bl-SIC 7&A WHICH MAY NOT QE USED,
                                         321

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             u.s. ENVIRONMENTAL PROTECTION AGENCY
              NOTICE OF RESEARCH PROJECT
                                                  Fotm Approved
                                                 OMB No.
                                                       PROJECT NO. (Do not uae thin spac«>

                                                       SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                        EPA-IAG-D6-E721-BDQ
TITLE OF PROJECT
Ecological Recovery after Reclamation of Toxic Spoils Left by Coal  Surface
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL
 ROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

Thomas G. Zarger (615) 632-4411
Joe  B. Maddox
William M. Seawell
NAME AND ADDRESS OF. APPLICANT INSTITUTION
 Tennessee Valley Authority, Division of  Forestry,  Fisheries,  and Wildlife  '
 development,Morris, Term. 37828
  = vc.i.upmeiiutHui.i, j.a t xeim. j/o^o
  IMMARY OF PROPOSED WORK- (!) Objective. (2) Approach, <3) Current Plan* and/or Progress (200 words or less. Omit confidential data). fr
  In the Smithsonian Science Information Exchange, summaries of work In progress are exchanged with government and private agencies sup-   '.
  •rllng research and are forwarded to Investigators who request sueb' information. Your summary is to be used for these purposes.    " T.. ..''-',-

 3b1eetive; To  determine  the rate of recovery of a  damaged ecosystem in     •
response to  intensive  remedial  treatment  of a problem surface mine.   The
project involves a problem watershed in which 400  acres of  forested  land
were  disturbed by coal surface  mining in  the early 1970's.   Unsuccessful'
reclamation  efforts resulted in adverse environmental impacts within an
LI-square mile watershed that includes a  city water supply  reservoir.
.ooroach & Plans; Project objectives will be accomplished by applying in-  '
tensive remedial land  treatments  & evaluating their effectiveness by  .  ,  •;
neasuring the  degree of  recovery  of the affected terrestrial fit aquatic eco?
systems.  Environmental  data collected during the  period of  mining & early,
reclamation effort will  serve as  initial baseline  study data.  Monitoring
[soil,  vegetation & receiving stream ecology) is being conducted through   '
treatment & will be continued thereafter on a more limited basis as  long
is  significant recovery  is noted.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.
 dental, etc.)
                                    SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                     DATE

                                                     10/13/76
                                  FOR OFFICE USE ONLY
   SUPPORT METHOD f
                               1-4
                                          PROJECT OFFICER
                                          Thomas G.  Zarger
                                                                                •---I
                                          RESPONSIBLE ORGANIZATION
                                          TVA
 FUNDS O8LIGATED

 $70,000
76
     NO. OF,FUTURE YEARS TENTATIVELY
     ASSURED BEYOND CURRENT F.Y.
STARTING DATE

7/1/75
                                                                   ESTIMATED COMPLETION
                                                     1/31/81
 EPA Form 5740-1 (7-72)   REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                     322

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form
                                                                        OMIt No.
                                                PROJECT NO. fDo not u>e turn «»«•>

                                                SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLEOF PROJECT
     INFORMATION  SYSTEMS DEVELOPMENT
                                                                  EPA-IAG-D6-E72HBDR
OWE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

Dr. John S. Grossman, Biologist,  Water Quality and Ecology  Branch (Principal  Invest,)
James R. Wright,  Jr., Biologist,  Water Quality and Ecology  Branch (Research Invest.)
NAME ANO ADDRESS OF APPLICANT INSTITUTION
                                      Tennessee Valley Authority
                                      Division of Environmental  Planning
                                      Water Quality and Ecology  Branch
                                      Muscle Shoals, Alabama   35660
SUMMARY OF PROPOSED WORK - (I) Objectives, (2) Approach. (3) Current Plant anil/or Progress (200 words or les». Omit confidential data).
   to the Smithsonian Science Information Exchange, summaries of work in progress ara exchanged with government and private agencies sup-
porting research and are forwarded to investigator* who requeat such information. Ypur summary is to be used for these purposes.

The objective of  this task is  to develop the  capability to measure and  evaluate
existing and anticipated environmental impacts of energy-related technologies  on
important biotic  assemblages in the aquatic environment.

To accomplish this objective, representative  data sets have been tested using
various analytical techniques.   The techniques considered include correlation,
distance and association coefficient matrices, diversity indices, and various
cluster and ordination analyses.   Two other short-term projects  were undertaken
aa part of this  task—a hierarchical diversity study and a similarity coefficient
atudy to determine what coefficient(s) should be used when clustering biological
data  from stream surveys.

With  the completion of the data evaluation, species associations will be identified
for additional laboratory and field studies to determine their functional role
in the environment.   This information will subsequently be used  to adapt or
create statistical and/or ecosystem simulation models in order to accomplish the
Stated objective.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (
denial. t'lv.J

    Not  Applicable
                          SIGNATURE.JpFPftlNCtPAL INVESTIGATOR
                                  . /5Zft./&-*i~>
                                  S. Crossman
                                                      DATE

                                                      September 27,1976
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD (C/ircft •
                                                PROJECT OFFICER
                                                W.  R.  Nicholas.  Chief, Water Quality &
                                                RESPONSIBLE ORGANIZATION      Ecology Branch
                                                Tennessee Valley  Authority
FUNDS OBLIGATED

  57,000
F.Y.

 76
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYONO CURRENT F.Y,

          3.0
                                                         STARTING DATE
5/7/75
5/6/80
EPA Form 5760.1 (7-72)
                                RM 166 ANU SI-5IE 76A WHICH MAY NOT BE USED.
                                          323

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                       OA1B Wo. I
                                              PROJECT NO, (Da nal u
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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Farm Approved
                                                                        O.VD No. IW-KOOtSl
   PROJECT NO. (Do not use this spaeo)

   SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PROJECT

 BIOCHEMICAL METHODOLOGY. AQUATIC  THERMAL IMPACTS
                                                                  EPA-IAG-D6-E7 21-BDR
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

 Sylvia  A. Murray, Biologist, Water  Quality and  Ecology Branch (Principal  Investigator)
 Colette G.  Burton,  Biologist, Water Quality and Ecology Branch (Research  Investigator)
NAME AND ADDRESS OF APPLICANT INSTITUTION
                                         Tennessee  Valley Authority
                                         Division  of Environmental Planning
                                         Water Quality and Ecology Branch
                                         Muscle Shoals. Alabama   35660	
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words-or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to b« used for these purposes.


          The objective of this  task is  to investigate thermal impacts on bluegills
          as measured  by physiological and biochemical changes in the blood.   Our
          approach  is  to subject  the fish to various  thermal plume conditions  associated
          with constant and oscillating background temperatures.   Peripheral blood
          from the  caudal peduncle  is used for  morphological and chemical analyses,
          including microanalysis of the chemical constituents of the plasma.

          We have worked out most of our analytical methods on available fish—viz,
          catfish,  goldfish, and bluegills.   Currently, we are studying population
          density effects  on these  fish  to establish  carrying  capacities for
          maintaining  and  culturing fish for our  thermal experimental work.  To  date,
          we have obtained data on  catfish and  goldfish and have  initiated similar
          studies on bluegills.  The data are currently being  reduced for statistical
          analyses.  In addition, we are setting  up our baseline  studies on bluegills
          to characterize  the blood.
IDENTIFY PROFESSIONAL SCHOOL IN VOLVEO f.
          Not Applicable
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                SpA~-1 A-
                                                Sylvia  A. Murray
                September  27,  197
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD T/-CI:* i.ru-J
      fA«CH C«ANT
                                                PROJECT OFFICER
                                               W.  R.  Nicholas,  Chief, .Water Quality & Ecol,
                                                RESPONSIBLE ORGANIZATION                  Branch
                                               ,Tennessee Valley Authority
FUNDS OBLIGATED
  53,000
                 76
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
                                 3.0
                                                         STARTING DATE
5/7/75
                ESTIMATED COMPLETION.
                DATE
                                                                                S/6/80
EPA Form S760-J (7-72)    REPLACES PMS FORM ISG AND SI-SIE 76A WHICH MAY NOT BE USED.
                                          325

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                        OAlfl No. DS-ROOXl
                                                               PROJECT HO. f/>o not i/«0 tM»

                                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                   EPA- IAG-D6-E721- BDR
TITLE OF PROJECT
 BIOMONITORING, MOU.USKS,  ASP OTHERS
GIVE NAMES. DEPARTMENTS. ANO OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

 Billy G.  Isom, Biologist, Water Quality and Ecology Branch (Principal  Investigator)
 Charles  Gooch, Biologist, Water Quality and Ecology Branch (Research Investigator)
 Larry T.  Neill, Biological Aide, Water Quality & Ecology  Branch (Research Investigator)
NAME AND ADDRESS OF APPLICANT INSTITUTION
                                       Tennessee Valley Authority
                                       Division of  Environmental Planning
                                       Water Quality and Ecology Branch
                                       Muscle Shoals. Alabama   35660	
SUMMARY OF PROPOSED WORK - (1) Objective*. (2) Approach, (3) Current Plan, .nil/or Procre»> (200 word, or !•«».  Omit confidential data).
   In the Smithsonian Science Information Exchange, • ummaries of work in progres* are exchanged with government and private agencies cup*
porting research and are forwarded to inve»tig«tor» who request *uch information. Your • untnary 1* to be iu«d for the** purpoae*.


         The objective of this task is to quantify the role  of bioaccutnulation in
         cycling  of  trace elements  (selected metals and radionuclides)  released to
         aquatic  ecosystems by energy technologies (coal combustion and nuclear
         steam-electric stations).

         Studies  have  been conducted over the  past several years on mo Husk population
         species  distribution in Tennessee Valley reservoirs in proximity to coal
         combustion  and operational nuclear facilities.  We  have a limited knowledge
         of the use  of mussels and  macroinvertebrates as biological monitors of
         metals and  organochemical  species.

         We have  considerable background literature on toxicity of power plant chemicals
         to aquatic  life.  This  research will  further evaluate  the use  of  mo Husks
         and other invertebrates  for monitoring bioaccumulation in the  aquatic
         environment.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical,
•  \till, L'(f. >

  	Not Applicable	
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                 September 27.  197
   SUPPORT METHOD (Chvck UH.-J
 Xii
   63,000
                76
                                      FOR OFFICE USE ONLY
                                                PROJECT OFFICER
                                               H.  R.  Nicholas.  Chief. Water Quality &  Eeol
FUNDS OBLIGATED  F.r.    NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
                                                RESPONSIBLE ORGANIZATION

                                                Tennessee Valley Authority
                                 3.0
                                                         STARTING OAT£
5/7/75
5/6/80
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 16C AND SI-SIE 76A WHICH MAY NOT DE USED,
                                          326

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
     OF PROJECT
                                                                       d.vn
                                                                            Aftfirorctt
      PROJECT NO. I
      SSIE
                                                                  EPA-IAG-D6-E721- S
j;  EVALUATE WATER  INTAKE. ZOOPLANKTON ENTRAIKMENT
OWE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

54  Dr. Richard D.  Urban, Biologist, Water Quality & Ecology  Branch (Principal  Invest.)
   Donald L. Dycus,  Biologist, Water  Quality & Ecology Branch (Research  Investigator)
NAME AND ADDRESS OF APPLICANT INSTITUTION
                                       Tennessee Valley Authority
                                       Division of Environmental Planning
                                       Water Quality and Ecology Branch
                                       Muscle Shoals. Alabama  35660
SUMMARY OF PROPOSED WORK -  (1) Objective,, (2) Approach. (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
, ;  In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and ar« forwarded to investigators who request such information. Your summary is to be used [or these purposes.

*  The objective of the research  project is to determine the best type of intake
 -  design to mitigate deleterious effects to the zooplankton community of a water
;...;  body.  To accomplish this goal,  several different types of intake designs  and
 '  sitings of  these intakes will  be evaluated as to the  rate of entrainment,  the
.£  percentage  of the community  entrained, and the possible effects of the entrain-
 j  ment upon the community.  The  results of this research will permit a  description
 ;  of zooplankton distribution  in response to naturally  occurring phenomena  (e.g.,
   currents, thermal stratification, pressure changes  induced by objects  in  the
.'''•  water column, etc.) to be made.   By knowing these responses, criteria  can  be
 j  developed for use in designing and locating intakes which will minimize the
'•  entrainment of zooplankton.

,:'  Specific studies will generally  conform to the following format.  The  horizontal
' '••  and vertical  distribution of the organisms in a water mass upstream of the
",;  intake, at  the intake, and dox?nstream of the intake zone will be determined
„   (i.e., the  same water mass).   In addition, temperature, current direction, and
••'!  current velocity data for various depths will be collected.  A second  phase
 *  will be to  assess in the laboratory the avoidance behavior of zooplankton  to
 ;  currents and  pressure changes  resulting from different-shaped objects  placed
 •  in the water  column.

 r  Entrainment effects (316b) studies were initiated in  1974 at eleven TVA
ft  fossil-fueled steam-electric stations.  Data from these studies have  been  used
,,t  as  guides for selecting appropriate study sites.  Intake evaluation will be
 -  conducted at  Gallatin, Johnsonville, Bull Run, Browns Ferry, and Colbert
"•  steam-electric stations.	
IDENTIFY PROFESSIONAL SCHOOL INVOLVEO f.U
Uvritjil, t-re.J
 :  Not Applicable
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                             Richard D.  Urban
                                                                          September 28. l°7ij
                                      FOR OFFICE USE ONLY
FUNDS OOLIGATEO
  67,000
                 76
                                               PROJECT OFFICER
                                               >. R. Nicholas,  Chief. Water Qxiality & Ecol.
                                                                              Branch
                                               RESPONSIBLE ^M^
                                               Tennessee  Valley Authority
                     NO. OF FUTUHC- YEAFIS TENTATIVELY
                     ASSURED DEyONO CURRENT F.Y.
                                3.0
STARTING DATE

    5/7/75
ESTIMATED COMPLETION
DATE
                                                                              5/6/80
EPA Form 5760-1 (7-72)    REPLACES PMS FO«M !M ANO il-SIE J6A WHICH MAY NOT 3E USEO.
                                        327

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Fttrm
                                                                        Alri No.
                                                              PROJECT NO.'fOo nut MM* IMH i
                                                              SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                               EPA-IAG-D6-E764 78  BED
TITLE OF PROJECI  Assessment of impaccs  of mining and  airborne pollutants on forest,
  range,  and _related_ freshwater ecosystems.
GIVE NAMF;S, HI-HAHTMLNTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PEHSUNNEL ENCAGED IN THE PROJECT.   Coordinated studies by Forest Service Research
 scientists underway at  several  locations in  the West,  Northern Great Plains, and East
 being conducted by:   Director,  Rocky Mountain Forest and Range Experiment Station,
 240 West Prospect Street, Fort  Collins, Colorado  80521, (303) 484-6270; Director,
 Intermountain Forest and Range  Experiment Station, 507 25th Street,  Ogden, Utah  84401,
 (801)399-6361;  (continue on attached-Sheet)	.	        	1
NAME AND ADONESS OF APPLICANT INSTITUTION
 U.S. Department of  Agriculture
 12th & Independence Ave., S.W.
 Washington, D.C.  20250	              	
SUMMARY OF PROPOSED WORK - <|) oh,.-,-li.,-s, (1} Approwli. O) Current Plans anil/or Progrt.j (200 words or let*. Orr.il eonlidrnli.l data).
    111.- Sm
           iind .irr f^rwurdod l.t
                                   request such inrormation. Your summary !• lo bf used for thece purposes.
                                                                                        • up-
 1.   Assess quality of water in water bodies in strip-mined areas as  it relates
 to  habitat for aquatic organisms  and wildlife species associated with these
 water bodies.

 2.   Assess teghnologies for redopositing and stabilizing mine spoils to include
 identification of technologies  that will keep water quality within acceptable
 limits for aquatic organisms and  associated wildlife species.

 3.   Assess effects of mining-related transportation systems on water, air, soil,
 plant, animal, and esthetic resources.

 4.   Develop operational technical information system for reclamation of lands
 affected by mining.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (.v.-,ft,'..l,
(Trrir.ir. i-fr. >

            NA
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                              9-13-76
                                      FOR OFFICE USE ONLY
           [ 1' C ON TH l\C T
$583,000        76        Three
                                  1-4
                                               PROJECT OFFICER
                                               R.2 . Callaham
                                               RESPONSIBLE
FUNDS OBLIGATED  F.Y.    NO. OF FurunC VEAH5 TENTATIVELY
               1       ASSURED BEYOND CURRENT F.Y,
                                              —	  --,     Forest Environment
                                                Research, Forest  Service, USDA
                                                        STARTING DATE-*-      ESTIMATED COMPLETION
                                                                           DATE
                                                          1975
                                                                                 1979
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-5IE 76A WHICH MAY NOT S£ USED.
                                           328

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              Continues from Page 1
Give Names, Departments, and Official Titles of Principal Investigators
or Project Directors and all other Professional Personnel Engaged in
Eho Project.	

and Director, Forest Environment Research Staff, 12th & Independence Ave.,
S.W., Washington, D.C.  20250, (703) 235-1071.
                             329

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
TITLE OF PROJECT
                                                                          Form Approved
                                                                        OMB No.
                                               PROJECT NO. (Do not u.« U|I> space)

                                               SSIE
                                                                     BFO
   Resource Inventory. Monitoring and Analyst* System (EIMaS)
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
   Nelson. William C., Assoc. Prof.,  Agricultural  Eeoncmica» Principal  Investigator
   Johnson*  Jerome E.» Professor, Agricultural Economic*
   Barker, William T., Assoc. Prof.,  Botany
   Omodt. Hollis W.,  Professor, Soil*
NAME AND ADDRESS OF APPLICANT INSTITUTION
   Agricultural Experiment Station
   Borth Dakota scat* Oniveraity
   Fargo. HO  5S102
SUMMARY OF PROPOSED WORK - (1) objectives, (2) Approach, (3) Current Plan* and/Of Prognaa (200 word! or laa*. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research arid are forwarded lo investigators who request such information. Your summary is to be ua«d for thea* purpoaes.

  Expand tit* Baaflurc* Inventory, Information Uoaagtawnt and Monitoring Sytttm (RdS) by
  adding coal related natural reaoutett, soeloeecnoaBle and etsTlraaoKBtal inforaatloB and
  adapting the General Eovironnental Hodel (GSM)  to interact with BOB.  Sianlat*
           of coal dcvalopo«nt by geographic areaa and prorlda deelalcn oakera with
  infonaatiCB on potential iapacts.   Data required to operate (ZH ea the Hordli Dakota
  coal  area will be obtained from other research projects and SOB* secondary •oareea.
  Baseline data will  be inputted and stored in KIMS.  Linkages will be contracted to
  transfer data frtm  KDS to Q3L.  GEM will be selectively modified and tested against
  other impact projects to accurately represent  the North Dakota coal area.  Ine final
  phase will apinttlate coal development iapeets  upon the land, people, ecoocoiy and
  govemnent fa. the area under varying conditions.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Mcilic
drntitl, cfc.l

  Agricultural Experiment Station
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                               10/5/76
    AGENCY 5T
FUNDS OBLIGATED
  220K
76
                                      FOR OFFICE USE ONLY
                                               PROJECT OFFICER
                                                M. L. Wilson
                                               RESPONSIBLE ORGANIZATION
                                                 CSRS-USDA
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
                                                         STARTING DATE
S/76
ESTIMATED COMPLETION
°ATE  6/78
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                              330

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               U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OTRESEARCH PROJECT
      PREPARED FOR THE SMITHSONrXM SCIENCE INFORMATION EXCHANGE
                                                                          Form Approved
                                                                        OMB No. 158-RODS I
                                                       PROJECT NO. (Do not uee this spmce)

                                                       SSIE
                                                       EPA—
                                                        BFO
             Inventory. Monitoring, and Analyaia Syateaf-Phase II
 GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIOATORS OH PROJECT DIRECTORS AND ALL OTHER
 PROFESSIONAL PERSONNEL ENGACED IN THE PROJECT.
'NAL PERSONNEL ENGACED IN THE PROJECT.

m, VilUa* C.. AMOS. Prof.. Agriealtaral Scaa
MO. Jerone K.» Professor, Agricaltural EcananJ
tf. eHllfoem T_  oteeuH.  9~n£ _   9n*m**m
                    I 1*.« AOMHOC.  rcw. f> «B>r4.VffAa«aB¥
   jonnaoa. jeroae K.» Profeasor, Agricaltural
   Barker. RilliaM T., Aaaoc.  Prof.. Botany
   Oaodt, Hollia «., Profeaaor. Soil*
                                                                • Principal  Inveattsator
 NAME AND ADDRESS OF APPLICANT INSTITUTION
   Agricultural Bxperlneat Station
   Berth Dakota State University
   Fargo. HP   58102
 SUMMARY OF PROPOSED WORK - (1) Objective., (2) Approach. (3) Cwr.nl Plan* and/or Prosr... (200 wonto or !=».. Omit COftTldentl*! data).
   In the Smithsonian Science Information Exchange, »unnurl«t of work In procresB are ezchanacd with lovenuwnt and private agencie* sup*
 porlinB research and are forwarded to Investigators who request such information. Your summary is to be uaed for these purposes.
   Expand cha  analytical capabllltlca of  KIHAS to *«tl..«t* tapaet* of cnergjr traaaaicaioi
 conHora and topacta o£  altci^atl«« MttO^aast pattacoa OBOB eoanualty scxviea* and
 tranaportaticn ayrtMtv   Adapt aad apply co-positc napping to analyze  energy davelop-
     : latpaetA on land oa«  and cower; and to identify areas where trinina will have mini-
 wm negative effect*.  A  coasiatariead aliemlatio.. aodel will be oaed  60 predict trana-
 KUalon corridor and settleMUt patteroa  and their ija>aetar the prcdlctiona will be
 Ahspareti to  ofiier analyaea and to reality, and the aodel will be oodified aa neceaaary
 to achieve accurate and rueful rtwulta.  Soila. wgetadoa... coal •vcrbordea. ground
 water and other characterictica will be digitised and  need ac input* to a coopoaite
 •apping ayatem to Identify potaadal oinlng areaa and  aenitor land oca changim doe to
 coal development.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Mc
 (AMKiif. ffr. I
 J.griealtur»X Ezperlatid: Station
                                          SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                         10/S/76
                                       FOR OFFICE USE ONLY
    SUPPORT METHOD (C/iri-k omO
 FUNDS OBLIGATED
   $220K
         76
                                        PROJECT OFFICER
                                         M.  L.  Wilson
                                                RESPONSIBLE ORGANIZATION
                                                 CSRS-USDA
                       NO. OF FUTURE YEARS TENTATIVELY
                       ASSURED BEYOND CURRENT F.Y.
                                                          STARTING DATE
                                                   S/76
                                                                             ESTIMATED COMPLETION
                                                                                  6/78
• 6PA Form 57«M (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                            331

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E.  INTEGRATED ASSESSMENT

-------
                      TABLE OF CONTENTS




                     Integrated Assessment
Agency




 EPA




 TVA




 USDA
 Page




332-341




342-345




  346

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              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                         Form Approved
                                                                       OMB NO.
                                                              PROJECT NO. (Do not umm thtm apace)

                                                              SSIE
                                                                     ccc
 ITLE OF PROJECT
   Geothermal  Systems/Environmental Assessment  of Extraction,  Conversion §  Waste Disppsa
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   Donald  B.  Gilmore - Project Officer         MSA/EMSL-.LV
   Alan  Crockett - Principal  Investigator      MSP/EMSL-LV
   William Sutton - Principal Investigator     MSE/EMSL-LV
NAMe AND ADDRESS OF APPLICANT INSTITUTION
   U.S.  Environmental Protection Agency,
   Environmental Monitoring and Support Laboratory, P. 0.  Box 15027;
   Las Vegas,  NV  89114.	
SUMMARY OF PROPOSED WORK - (I) Objectives, (2) Approach, (3) Current Plans and/or Proere» (200 word, or lets. Oratt conf.d.mia 1 data).
porting research and are forwarded to investigators who request such information. Your lummBry 1m to b« u»*d (or th*B« purpooi.

   Objective:   To evaluate  the effect   of geothermal resource  development  derived
                pollutants on the local  species;  to furnish  information  for an
                integrated monitoring system around any geothermal resource development.

   Approach:   Samples  from plants and  animals in the vicinity of geotherraal develop-
                ment  areas are being analyzed on a quarterly basis and are  being
                compared to  control areas.   Effect of geothermal pollutants will be
                noted and included as a  part of the total monitoring  strategy.
   Current
        Plans:
                Initial  sampling has been  done.   Extractions  and analyses  are in the
                process  of completion.   Sampling and analyses are contemplated on a
                quarterly basis with quarterly letter progress reports and annual
                reports  covering conclusions as well as recommendations for the
                succeeding year's activities.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED ( A/,-,/iV.(/,
          NONE
                                         SIGNATURE OF^PRINCIPAL^CNygSTIGATOR
                                                        9/28/76
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD [Ch,t, HIM-)
   $198.5K
                 76
                                               PROJECT OFFICER
                                                 Donald  B.  Gilmore
                                               RESPONSIBLE ORGANIZATION
                                                 HSD/EMSL-LV
ASSURED BEYOND CURRENT F.Y.

     4
STARTING DATE

  3/76
                                                          3/81
EPA Form 5760-1 (7-72)    REPLACE? PHS FORM 16P AND SI-SIE 76A WHICH MAY NOT BE USED.
                                          332

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                        Form Approt-ed
                                                                      OA1B \o.
                                             PROJECT NO. (Do not use this apace.)
                                             SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                    ccc
Geothermal Systems /Environmental Assessment of Extraction. Conversion,  and Waste
 IVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
 HOFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.                                    JDlSpOSal
Dr. Tsvi Meidav, Principal Investigator
NAME ANO ADDRESS OF APPLICANT INSTITUTION
Geonomics, Inc.
3165 Adeline Street
Berkeley. CA  94703	
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach, (3) Current Plans and/or Progress (200 words or less. Omit confidential data).
   tn the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used [or these purposes.
Objective:
Approach:
 Current
  Plans:
A guideline document will be developed for the multimedia monitoring
strategy around any geothermal resource  development.  A handbook
of referenced geothermal sampling techniques and sample analyses
will be developed.

A contractor has been selected to adapt a.  previously developed
groundwater monitoring strategy to geothermal resource developments
The East Mesa Area of the Imperial Valley,  California, has  been
selected..  All background data involving geology, hydrology,
effluent constituents, ongoing groundwater monitoring programs, and
resource developments and possibilities will be collated into a
beginning report.  The groundwater monitoring strategy will be
developed  and implemented.
Collection of baseline data has been started.  Implementation of
monitoring is expected to begin about 6/77.
 IDENTIFY PROFESSIONAL SCHOOL INVOLVED r
 dentn/, etc.)

 NONE
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                           DATE

                                                            9/28/76
                                       FOR OFFICE USE ONLY
    SUPPORT METHOD (Check one)
 FUNDS OBLIGATED

 $201.5K
 76
                               PROJECT OFFICER
                                 Donald B.  Gilmore
                                               RESPONSIBLE ORGANIZATION
      NO. OF FUTURE YEARS TENTATIVELY
      ASSURED BEYOND CURRENT F.Y.
STARTING DATE

   9/76
                                                                 9/81
 EPA Form 5760-7 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A .WHICH MAY NOT BE USED.
                                             333

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                       OMB No. VS-R008I
                                              PROJECT NO. (Do nol u«e thim mpfce)

                                              SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                     CCC
TITLE OF PROJECT
                Site Engineering and Waste Management for  Radioactive Waste Bunal
Give "NAMES. EPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIOATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
  Mr. David Ross
  SCS Engineers
  4014 Long Beach  Blvd.
  Long Beach, CA   90807   '(213)  426-9544
NAME ANO ADDRESS OF APPLICANT INSTITUTION
  U.S. Environmental  Protection  Agency, Office of Radiation  Programs-Las Vegas Facility,
  P.O. Box 15027,  Las Vegas, Nevada  89114.
  (702) 736-2969 ext. 305    FTS:   595-2969 ext.  305              	
SUMMARY OF PROPOSED WORK - (I) Objective!. (2) Approach, (3) Currant Plane and/or Progreaa (200 wort, or leaa.  Omit confidential data).
  In the Smithsonian Science Information Exchange, auntmarlea of work in progreaa are exchanged with government and private agencies sup*
porting research and are forwarded to Investigator* who requekt »ueh Information. Your •ummary la to be u««d for these purpoaaa.

 The contractor shall summarize and discuss engineering and water management  practices
 that minimize  the infiltration of  precipitation  into trenches containing radioactive
 waste.  Using  literature surveys and inhouse  expertise, the contractor shall  summarize
 proven practices, proposed studies, and pilot demonstration projects.   The contractor's
 expertise shall be required to synthesize and to apply this data base to the shallow
 land burial of containerized  (drums, boxes, etc.)  radioactive waste.

 Specific efforts  shall be directed toward, but not limited to, the following topics:

      a.  Trench and trench cap design
      b.  Backfilling and compaction requirements
      c.  Site  erosion control  and  reyegetation                                   •
      d.  Relative costs of implementing alternatives for  items 1-3
      e.  Methods  to-evaluate  the site water budget

 Supportive  conclusions shall  be  supplied by the  contractor as to which practice or
 combination of practices in the  long run, will result in  minimal water saturation of
 waste and maximum surface stabilization so as to minimize perpetual care and mainte-
 nance.  This shall be accomplished by applying:

      1.  Contractor expertise and  rationale to evaluate the practices/methods des-
          cribed,  and
      2.  Case  histories or recent  research results
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.
denial, etc.)
   SUPPORT METHOD fOiocl on,.;
    AGENCY STAFF (7ntn
    RESEARCH GRANT
                              PROJECT OFFICER

                               Michael  F.  O'Connell  (702)  736-2969  ext.305:
                                               RESPONSIBLE ORGANIZATION It C  FDA   QRP-I VF

                                                P.O.  Box 15027.  Las Vegas. Mevada  89114
FUNDS OBLIGATED
   $18.4K
76
                     NO. OF FUTURE YEARS TENTATl\
                     ASSURED BEYOND CURRENT F.Y.
None
STARTING DATE

 October 10, 1976
                                                           ESTIMATED COMPLETION
                                                           DATE
                                                            July 1977
EPA Form 5760*1 (7-72)    REPLACES PHS FORM 166 AND S1-S1E 76A WHICH MAY NOT BE USED.
                                           334

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                        OMB No. 158-R0081
                                                 ROJECT NO. (Da not use this

                                                5SIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                    CSD
 Integrated Assessment of Coal Lease  Areas In the  Western United States
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OH PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

 Not Yet  Awarded.
NAME AND ADDRESS OF APPLICANT INSTITUTION
SUMMARY OF PROPOSED WORK - (I) Objective*. (2) Approach, (3) Current Plans and/or Progress (200 word* or less. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.

 The steady evolution of a new Federal Coal Leasing  Program,  the lifting of an  injunctio
 against  mining plln  approvals 1n  the Eastern  Powder River Basin as well as demands for
 moderate cost energy fuels such as low sulfur coals,  are all  facts which are placing
 unique environmental  pressures on the coal resources  of the  Western  United States.
 There is a need for  a systematic, uniform and  representative  classification 
-------
U.S. ENVIRONMENTAL PROTECTION AGENCY
NOTICE OF RESEARCH PROJECT
PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
Form Approved
OMB No. HS-ROOSl
PROJECT NO. fDo not use ?fif« »p«ce>
SSIE
EPA
CTA
  TLE OF PROJECT
     .io-Rivey-Basin Enprgy  Study
     •.MES. DEPARTMENTS, AND OFTHCIAL. TlTL
   _____
GIVE NAMES.
PROFESSIONAL
   Principal Investigator
   Professor Hugh T. Spencer
   Associate Professor of Engineering
   University of Louisville
   Louisville. Kentucky  40208
                                  LES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS ANO ALL OTHER
                           IN THE PROJECT.
NAME ANO ADDRESS OF APPLICANT INSTITUTION

   University of Louisville
   Louisville,  Kentucky   40208
SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach, (3) Current Plan* and/or Progress (200 word* or less. Omit confidential data).
  In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigator! who request such information. Your summary ia to be ue»d for theae purposes.

        This set of studies represents a portion of a multi-institutional policy-
  oriented technology  assessment of the socioeconoraic and environmental impacts
  which might result from  a proposed increased  concentration of energy conversion
  facilities within the Ohio River Basin.

        Utilizing the best  available data bases, these studies will attempt to
  address the broad-scale  environmental, institutional, economic and social effects
  of  various future combinations of energy conversion facilities.tj.e., coal-based plants
  producing synthetic  fuels, as well as nuclear and coal-fired  electric power
  generating plants) and their required support facilities  (i.e., coal mining,
  processing and transportation; ash and sludge disposal facilities;  nuclear
  fuel and reactor waste transportation facilities; and energy  transportation systems,
  including electrical power transmission  systems) that might be built and operated
  in this region in the future.

        The principal objectives of this assessment are (1)  to  assist in outlining
  the full range of policy options for dealing  with selected kinds of development,
  alternative levels of development and their possible undesirable effects, and
  alternative technological levels of environmental controls; and C2) to analyze
  the probable  impacts that would result from Implementing  each option in its total
  framework, with  special  emphasis on the  natural environment  and its inter-
  relationship with public health and welfare.   The full range  of primary,
  secondary, and higher order effects will be considered.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Mcit
 """Environmental Engineering
    Speed scientific  School
                                        SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                            July.  1976
                                      FOR OFFICE USE ONLY



X
SUPPORT METHOD (Cli.u-k ant-)



FUNDS OBLIGATED
$55,888
F.Y.
1976
TASK NO.
5D
PROJECT OFFICER
Lowell Smith
RESPONSIBLE ORGANIZATION
Office of Energy, Minerals and Industry
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
STARTING DATE
Julv 29, 1976
ESTIMATED COMPLETION
DATE
Julv. 1978
EPA Form 5740.1 (7-72)
                   REPLACES PHS FORM 166 ANO SI-SIE 76A WHICH MAY NOT BE USED.
                                         336

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCV
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                        OMB No.  1SS-KOOS1
                                                               PROJECT NO. (Da not u.e Ihie space.)

                                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                CTA
   Ohio River Basin Energy Study
   EWAMES. DEPARTMENTS. AND accir-in TIT,
         aj.vtsi. gasjji energy ST;UQV
oaTrT^r.""'*' DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   Co-Principal  Investigators:
   Professor Donald A. Blome
                                                   Professor James E. Jones, Jr.
NAME AND ADDRESS OF APPLICANT INSTITUTION

    University of  Kentucky
    Lexington, Kentucky  40506
SUMMARY OF PROPOSED WORK - (1) Objective.. <2> Approach. (3) Current Plan, and/or Progress (100 words or less. Omit confidential data).
   In rhe Smithsonian Science Information Exchange, summaries of work In progress are exchanged with government and private agenclea sup-
porting research and are forwarded lo investigator* who request such information. Your summary !• to be used for th*a« purpoaea.

       This set of studies  represents  a portion of a multi-institutional policy-
  oriented  technology  assessment  of  the socioeconomlc  and environmental Impacts
  which might result from a proposed increased concentration of energy conversion
  facilities within  the Ohio River Basin.

       Utilizing the best available  data bases, these  studies will attempt to
  address the broad-scale environmental,  institutional,  economic and social effects
  of various future  combinations  of  energy conversion  facilities (I.e.,  coal-based plants
  producing synthetic  fuels, as well as nuclear and  coal-fired electric power
  generating plants) and their required support facilities (I.e., coal mining,
  processing and transportation;  ash and sludge disposal facilities; nuclear
  fuel and  reactor waste transportation facilities;  and  energy transportation systems,
  including electrical power transmission systems) that  might be built and operated
  in this region in  the future.

       The  principal objectives of this assessment are (1) to assist in outlining
  the full  range of policy options for dealing with  selected kinds of  development,
  alternative levels of development  and their possible undesirable effects, and
  alternative technological levels of  environmental  controls; and  (2)  to analyze
  the probable impacts that would result from implementing each option in its total
  framework, with special emphasis on  the natural environment and its  Inter-
  relationship with public health and  welfare.  The  full range of primary,
  secondary, and higher order effects  will be considered.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED C.Worfiail.
r.-i/, t-rr. >

    Institute  for Mining  and Minerals
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                             July, 1976
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD (Cht't-k i
    AGENCY STAFF (/;irr.Tn«jra/)
                                   5D
                                               PROJECT OFFICER
                                                Lowell Smith
                                                RESPONSIBLE ORGANIZATION
                                                Office of Enerw, Minerals and Industry
FUNDS OBLIGATED
    $70,060
               F.V.

               1976
NO. OF FUTURE YEARS TENTATIVELY
ASSURED 8EYOND CURRENT F.Y.
STARTING DATE

 July 29, 1976
ESTIMATED COMPLETION
DATE
    July, 1978
EPA Form 5760-1 (7-72)
                   REPLACES PHS FORM 166 AND SI-5IE 76A WHICH MAY NOT BE USED.
                                           337

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTiCE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                       OMB No. H8-ROOS1
                                                              PROJECT NO. (Do not U99 thta apace)
                                                              SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                              EPA
                                                               CTA
  TLE OF PROJECT
OIVE NAMES/DEPARTMENTS, AND OFFICIAL TITL
                                  LES OF PRINCIPAL INVESTIOATORS OH PROJECT DIRECTORS ANO ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   Co-principal Investigators!
   Professor James S. Stukel
   Director  Office of Energy Research
                                                   Professor Boyd R. Keenan
                                                   Professor, Dept.  Political  Science
NAME AND ADDRESS OF APPLICANT INSTITUTION

   University of Illinois
   Urbana,  Illinois  61801
SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach, (3) Currant Plan* and/or Pregreaa (200 worda or leaa. Omit confidential data).
   In ihf Smithsonian Science In/ornuitlon Exchange, summariei of work in progreaa are exchanged with government and private agenclea aup-
porling research and are forwarded to investigators who requeat guch information. Yow eummary la to be uaed for theae purpoaea.

      This set of studies represents  a portion of a multi-institutional policy-
  oriented technology assessment of the socioeconomic and environmental  impacts
  which  might result  from a proposed increased concentration of energy conversion
  facilities within the  Ohio River Basin.

      Utilizing the  best available data bases, these studies will attempt  to
  address the broad-scale environmental, institutional,  economic and  social effects
  of various future combinations of energy conversion facilities (i.e., coal-based plants
  producing synthetic fuels, as well as nuclear and coal-fired electric  power
  generating plants)  and their required support facilities (i.e., coal mining,
  processing and transportation; ash and sludge disposal facilities;  nuclear
  fuel and reactor waste transportation facilities; and energy transportation systems,
  including electrical power transmission systems) that  might be built and  operated
  in this region in the  future.  -                                              *

      The principal  objectives of this assessment are  (1) to assist  in  outlining
  the full range of policy options for dealing with selected kinds of development,
  alternative  levels  of  development and their possible  undesirable effects, and
  alternative  technological levels of  environmental controls; and (2) to analyze
  the probable  impacts  that would result from Implementing each option In  Its total
  framework, with special emphasis on  the natural environment and its inter-
  relationship with public health and  welfare.  The full range of primary,
  secondary, and higher  order effects  will be considered.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Medical.

   Civil and Mechanical  Engineering
   Pft^r-t-manti of Pnl it-.inal  Science
                                                                           July.  1976
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD :CVn'.-fc t
    RESEARCH GRANT
                                   5D
                                               PROJECT OFFICER

                                                 Towel 1 Smith
                                                                TION
                                                 Office of  Energy.- Minerals  and Industry
FUNDS OBLIGATED

$163,495
               F.Y.

                1976
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
STARTING DATE

   July 29, 1976
                                                                             July, 1978
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                         338

-------
              U.S. ENVIRONMENTAL PROTECTION ASENCY
                NOTICE OF RESEARCH PROJECT
                                                                        Form Approved
                                                                      OMB No. D8-R0081
                                                              PROJECT NO. (Oo not use this apace)

                                                              SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                CTA
 TLC OF PROJECT
   Ohio River Basin Energy Study
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
   Co-Principal Investigators:
   Professor Robert E.  Bailey
   Assistant Head of  Interdisciplinary
     Engineering Studies
                                                     Professor J. C.  Randolph
                                                     School of Public and Environmental
                                                     Affairs
NAME AND ADDRESS OF APPLICANT INSTITUTION

    Purdue University
    West Lafayette,  Indiana  47907
                                                     Indiana University
                                                     Bloomington,  Indiana  47401
SUMMARY OF PROPOSED WORK -  (1) Objectives. (2) Approach. (3) Currant Plan* and/or Progress (200 word* or less. Omit confidential data).
   In the Smithsonian Science tnfornuitton Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your sumoarv is to be used for these purposes.

        This set  of  studies represents  a portion of a multi-institutional policy-
   oriented technology assessment of  the socioeconomic and environmental impacts
   which might result from a proposed increased concentration of  energy conversion
   facilities within the Ohio River Basin.

        Utilizing the best available  data  bases, these studies will attempt  to
   address the broad-scale environmental,  institutional, economic and social effects
   of  various future combinations of  energy conversion facilities(i.e., coal-based plants
   producing synthetic fuels, as well as nuclear and coal-fired  electric power
   generating plants) and their required support facilities  (I.e., coal mining,
   processing and transportation; ash and  sludge disposal  facilities; nuclear
   fuel and reactor  waste transportation facilities; and energy  transportation  systems,
   including electrical power transmission systems) that might be built and  operated
   in  this region in the future.

        The principal objectives of this assessment are  (1)  to assist in outlining
   the full range of policy options for dealing with selected kinds of development,
   alternative levels of development  and their possible undesirable effects, and
   alternative technological levels of  environmental controls; and C2) to analyze
   the probable impacts that would result  from implementing  each option  in its  total
   framework, with special emphasis on  the natural environment and its inter-
   relationship with public health and  welfare.  The full  range of primary,
   secondary, and higher order  effects  will be considered.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED (Metl,

  Nuclear Engineering             Affairs
  Snhool nf Public and Environmental/
                                                                           DATE

                                                                             July,  1976
                                      FOR OFFICE USE ONLY
   SUPPORT METHOD (
    RESEARCH GH A
                                    5D
                                               PROJECT OFFICER
                                                Lowell Smith
                                               RESPONSIBLE ORGANIZATION
                                                Office Energy,  Minerals and  Industry
 FUNDS OBLIGATED
                 1976
                      NO OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
                                                        STARTING DATE
                                                          JT_my29. 1976_,
                                                                                 FED COMPLETIOI
                                                                             _Julv. 1978
 EPA Form 5740-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                            339

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                        OMB No.  158-ROOgl
                                                PROJECT NO. (Do not uae rjifs sp«caj

                                                SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                   CTA
   Ohio River Basin  Energy Study
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL E.NGACED IN THE PROJECT.
    Principal Investigator:
    Professor Ross  J.  Martin, Director,
    Engineering Experiment Station
    Professor of Mechanical Engineering
NAME AND ADDRESS OF APPLICANT INSTITUTION

    University of  Illinois at Urbana-Champaign
    Urbana, Illinois  61801	
SUMMARY OF PROPOSED WORK - (1) Objectives. (2) Approach. (3) Current Plan, and/or Proireas (JOO word, or lass. Omit confidential data]
   In the Smithsonian Science Information Exchange, summaries of work In proBTeas are exchanged with government and private agencies sup-
porting research and are forwarded to investigator* who request such information. Your summary Is to be ua«d for these purposes.

        This  set  of  studies represents a portion  of  a multi-institutional policy-
   oriented technology assessment of the socioeconomic and environmental impacts
   which might result  from a proposed increased concentration of  energy conversion
   facilities within the Ohio River Basin.

        Utilizing  the  best available data bases,  these studies will attempt to
   address the broad-scale environmental, institutional, economic and  social effects
   of  various future combinations of energy conversion facilitiesCi.e.,  coal-based plants
   producing synthetic fuels, as  well as nuclear  and  coal-fired electric power
   generating plants)  and their required support  facilities Ci-e.,  coal  mining,
   processing and  transportation;  ash and sludge  disposal facilities;  nuclear
   fuel and reactor  waste transportation facilities;  and energy transportation systems,
   including electrical power transmission systems) that might be built  and operated
   in  this region  in the future.

        The principal  objectives  of this assessment are (1)  to assist  in outlining
   the full range  of policy options for  dealing with  selected kinds of development,
   alternative levels  of development and their possible undesirable effects, and
   alternative technological levels of environmental  controls; and  (2) to analyze
   the probable impacts that would  result from implementing  each  option  in its total
   framework, with special emphasis on the natural environment and  its inter-
   relationship with public health  and welfare.  The  full range of primary,
   secondary, and  higher order effects will be considered.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED W
ifrntiif. .-!<•.)
            nf Fngi nooiH r,rr
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                            July,  1976
                                      'FOR OFFICE USE ONLY
    JEGOTIATED CONTRACT
    RESEARCH GRANT
                                   3D
                                RESPONSIBLE ORGANIZATION

                                        ri-F FnQi-fjy,  M-ino-rala
                                                                                 Tnr1«a<-r-y
FUNDS OBLIGATED
    $188,305
1976
                      NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
                                         STARTING DATi:

                                         July 29, 1976
July, 1978
EPA Form 5740-] (7-72)
                   REPLACES PHS FORM 166 AND SI-SIE 76A WHICH MAY NOT BE USED.
                                           340

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                       OMB No. VS-R0081
                                               PROJECT NO. (Do not an Ihl,

                                               551E
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                    CTA
    Ohio River Basin Energy Study
GIVE NAMES. DEPARTMENTS, ANO OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.

    Principal  Investigator:
    Professor  Robert C. Stiefel
    Director,Water Resources  Center
NAME AND ADDRESS OF APPLICANT INSTITUTION
    Ohio State University
    1791 Neil avenue
    Columbus,  Ohio  43210	
SUMMARY OF PROPOSED «ORK - (1) Objectives. <2) Approach, (3) Current Plans and/or Progress (200 word, or less. Omit confident..I d»t»>.
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary Is to be used for thes* purposes.

        This set of studies represents  a portion of a multi-institutional policy-
   oriented  technology assessment of the socioeconomlc and  environmental Impacts
   which might result from a proposed increased concentration  of  energy conversion
   facilities  within the Ohio River Basin.

        Utilizing the best available data bases, these studies will attempt to
   address the broad-scale environmental, Institutional, economic and social effects
   of various  future combinations of energy  conversion facilities(i.e., coal-based plant
   producing synthetic fuels, as well as nuclear and coal-fired electric power
   generating  plants) and  their required support facilities (i.e., coal mining,
   processing  and transportation;  ash and sludge disposal facilities; nuclear
   fuel and  reactor waste  transportation facilities; and energy transportation systems,
   including electrical power transmission systems) that might be built and operated
   in this region in the future.

        The  principal objectives of this assessment are (1) to assist in outlining
   the full  range of policy options for dealing with selected  kinds of development,
   alternative levels of development and their  possible undesirable effects, and
   alternative technological levels of  environmental controls;  and (2)  to analyze
   the probable impacts that would result from  implementing each  option in its total
   framework,  with special emphasis on  the natural environment and its inter-
   relationship with public health and welfare.  The full range of primary,
   secondary,  and higher order effects will  be  considered.
IDENTIFY PROFESSIONAL SCHOOL INVOLVED f
dt-lllul, ,•!<:>
    Civil Engineering
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                                                                             July, 1976
                                      FOR OFFICE USE ONLY
    AGENCY STAFF (In
                                   5D
                                               PROJECT OFFICER

                                                Taw-ell  Smith
                                               RESPONSIBLE ORGANIZATION
                                                Office  of Energy, Minerals and Industry
FUNDS OBLIGATED

 $96,867
F.Y.

 1976
NO. OF FUTURE YEARS TENTATIVELY
ASSURED BEYOND CURRENT F.Y.
TARTING DATE

 July 29, 1976
ESTIMATED COMPLETION
DATE
  July, 1978
EPA Form 5760-1 (7-72)    REPLACES PHS FORM 166 AND SI-SIE 76«- »HICH MAY NOT BE USED.
                                            341

-------
              U.S. ENVIRONMENTAL PROTECTION AGENCY
               NOTICE OF RESEARCH PROJECT
                                                                      Form Approved
                                                                     OMB NO.  /58-Roos;
                                        PROJECT HO. fOo mil u«« Ml

                                        SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                              EPA-IAG-D6-E721- BAZ
   Lime/Limestone and Advanced Concepts— TVA's 1-MW Pilot  Plant (Colbert)
GIVE NAMES. DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENCAGED IN THE PROJECT.
Dr. Gerald A. Hollinden,  Chemical Engineer, TVA Power Research Staff,  1320 Commerce Unloi
Bank Building, Chattanooga, Tennessee  37^01 Telephone:  615/755-3381,  FTS/85^-3381
Russell  F. Robards, Chemical  Engineer, TVA Power Research  Staff, 1320 Commerce Union
Bank Building, Chattanooga, Tennessee  37^01  Telephone: 615/755-3381,  FTS/85^-3381
NAME AND ADDRESS OF APPLICANT INSTITUTION

Tennessee Valley Authority
Knoxville, Tennessee
SUMMARY OF PROPOSED WORK- (I) Objectives.  Approach. (3) Current Plan. end/or Frotre»« (200 wordl or less. Omit eonlidentill data).

The objectives of  this  study are to determine the effects of gas velocity and solid-
liquid loadings on mist eliminator performance and to determine the mechanical and
chemical methods necessary to maintain continuous reliable operation.   The study is
to be carried out  at  TVA's 1-MW lime/limestone scrubbing pilot  plant  facility located
at the Colbert Power  Plant.   The initial mist eliminator designs are  formed from a
compilation  of data  received from previous pilot plant tests at TVA  and observations
of other research  projects throughout the world.

The 1-MW lime/limestone scrubbing pilot plant facility operated during this fiscal year
in the effort to develop reliable closed-loop mist eliminator washing techniques for
lime/limestone systems  where the mist eliminator is positioned  in  the vertical duct.
Systematic operation  of a Chevron-type mist eliminator led to a 1000-hour long-term
run in the limestone  mode and a 560-hour run in the lime mode.

Continuous operation  of the  Chevron-type mist eliminator, positioned  horizontally in a
vertical duct, in  the limestone system was maintained (after extensive testing) by
washing the bottom of the mist eliminator intermittently with a11  the  available clari-
fied liquor immediately followed by an allocated amount of the  allowable makeup water.
The top of the mist eliminator was  washed intermittently with the  remaining allocation
of allowable makeup water.  Continuous mist eliminator performance in the lime system
was maintained by  washing the bottom of the mist eliminator  intermittently with an
allocated amount of allowable makeup water.  The remainder of the  allocated makeup water
was used to intermittently wash the top of the mist eliminator.
IDENTIFY PfiOf-fSSION AL SCHOOL INVOLVED [
             N/A
                                                          INVESTIGATOR
                                                      9/27/76
                                     FOR OFFICE USE ONLY
               1976
                              : NO.

                                1
                        PROJECT OFFICER
                         Gerald A. Hollinden.  Russell F. Robards
                        RESPONSIBLE ORGANIZATION

                         Power Research Staff, TVA
ASMJFIED UEYONO CURRFNT F.Y
            0
STARTING DATE

May 7, 1975
                                                      December 1,  1971
EPA Forni 57*0-1 (7-72)    REPLACED Pus FORM 166 AND St-SIE 70A WHICH MAY NOT U£-triC,D.
                                         342

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form Approved
                                                                        OMB No. nS-ROOSl
                                                            PROJECT NO. (Do nor u«« this
                                                            5SIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                EPA-IAG-D6-E721- BDU
""-'<" ''"OJtcr  Develop Economic  Projection Modeling Capability Ii3cessary to Drive
          Modular Energy .and Environmental Planning Models  at a Multicounty Level
GIVE NAMtS, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AMD ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IM THE PROJECT.
          Project Director:  Hubert Hinote, Economist
                              Division of Navigation Development and Regional Studies
                              Tennessee Valley Authority
                              Knoxville, Tennessee  37902
	Tele-phone:  632-29W-	
NAME AND ADOKE&S OF APPLICANT INSTITUTION
                              Tennessee Valley Authority
                              Knoxville, Tennessee  37902
SUMMARY OF PROPOSED WORK - (1) Objectives, (2) Approach. (3) Current Plan, and/or Progress (200 word, or less.  Omit confidential dais).
   In thi- Smithsonian Scicnt-i- Itifurtnut ion Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting rmrjirirh aid *rc forwarded lo investigators who request such information. Your summary is to be used for these purposes.

    As a part of its ongoing economic research program, TVA is in the process of
    developing a Regional Economic  Simulation  Model of the  TVA region and its
    principal subregions.  The objectives of the present work  are to expand the
    existing model for use in:   (1) assessing  an area's sensitivity to various
    national parameters; (2) evaluating the impact in small areas (economic area
    or multicounty planning area) on population, labor force,  employment,  etc.
    of a major construction activity; e.g., construction of a  large nuclear energy
    plant;  and (3) providing the  macroeconomic data base at a  multicounty level
    that is necessary for rigorous  site specific analyses.   Much of the conceptual
    work has been done, but a  significant effort is required to make the model an
    operational tool for driving  energy and environmental planning models.   A
    demonstration of the two sector model (population-labor force and employment
    sectors) for a multicounty area will be completed by 12/76.
IDENTIFY PttJr-LSSIONAL SCHOOL IN VOL VED ,.Vi-.li

            None
                                       FOR OFFICE USE ONLY
   SUPPORT .MtTHOO if/u-,/. ...
AC. f_NC> 3T AIT (l,Ht."TI,r.,n
        HCM on AN T
r uNiv; ot»LiCAT ro TF.V.

  SX.     1976
                             TASK NO.
                                                PROJECT OFFICER
                                                Hubert Hinote	
                                                RESPONSIBLE ORGANIZATION TVA, Division Of
                                                Navigation Development and  Regional Studies
                  NO. OF FUTURE VEARS TENTATIVELY
                  ASSUMED OEVOND CURRENT F.V.
STARTING DATE

     5/7/75
ESTIMATED COMPLETION
DATE
Phase  I  Report-
3/77-  Final I960
EPA Faro. 5760-1 (7-72)^a   UrPLACLS f'HS FORM I6& AND SI-SIE 76A WHICH HAY NOT OE.USED,
                                           343

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form ApprovfJ
                                                                        OMR No. 758-ROOg;
                                                               PROJECT NO. (Do nor us* iMm soacej

                                                               SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                EPA-IAG-D6-E7S1 -BDV
TITLE OF PROJECT
Fleetrle Power  System Operation and Expansion Environmental Residual Model	
GIVE NAMES. DEPARTMENTS, AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT DIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Department - Systems Development Staff, Division of Fover Resource Planning,  Office of
D.  H.  Walters,  Supervisor
Floyd E. Davis, Power Supply Engineer
Mona M.  Breaux, Power Supply Analyst
                                                                                               Isver
NAME AND ADDRESS OF APPLICANT INSTITUTION
 Tennessee Valley Authority
 216 Power Building
SUMMARY OF PROPOSED WORK - (I) Objectives. (3) Approach. (]) Current Plans and/or Progress (200 words or less.  Omit confidential data).
   In the* Smithsonian Scicncr Information Exchange, summaries of work in progress are exchanged with government and private agencies sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.

 1.  Objectives - The objective of the project is to determine residual output from
     an integrated power  system.

 2.  Approach - Wevare using the model which will be based on a power system simulation,
     model  POVEISY1':* developed by OTA, but  will be capable of being used with other
     power  system simulation models.   It  will be capable of predicting the residual
     output cf a power system on a plact-by-plant basis as a function of time and
     extended over   two  or more decades.  The development is being coordinated
     with TVA Power Program Integrated Planning Model.

 3.  Progress - We are using the residuals  sulphur dioxide and gross particula^es to
     develop e. pilot residual report.  Specific emission rates  (in Ibs. per  10° BTU)
     for  sulphur dioxide  and participates for TVA. plants under an assumed abatement
     strategy have been obtained.  Programming on the  residual model for purposes
     of producing the pilot residual report has begun.


  "  A Stochastic Approach To Chronological Short Term Production Costing by
     Roger  A. Babb and R.  Taber Jenkins
Jriir.il. t-rr.)
       PROF-ESSIONAL SCHOOL INVOLVED f
            H/A
                                      FOR OFFICE USE ONLY
fJNDSOOLIG*TCD  F.Y.    NO. OF FUTURE. YEARS TCNTATIVGLY
                      ASSUHtD 9EYOND CURRENT F.Y.
                                                PROJECT OFFICER
                                                  Dr.  D.  H.  Walters
                                                RESPONSIBLE ORGANIZATION
                                                  TVA -  Office of Pover
                                                         STARTING DATE
                                                          5/75
                                                                                9/1980
tPA Form 5760-1 (7-72J    RE'l'l.ACt:S PHS FORM 106 AND SI-SIE "";A WHICH MAY NOT OE USED.
                                            344

-------
               U.S. ENVIRONMENTAL PROTECTION AGENCY
                NOTICE OF RESEARCH PROJECT
                                                                          Form f\pprof?d
                                                                        o.wfl N't.
          PROJECT NO. (Do not u«e thin space}

          SSIE
     PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                                    EPA-IAG-D6-E721- BEW
  TLE OF PROJECT
               Develop and Demonstrate Applications of Computer  Graphics to Site-
Specifie and Regional Integrated Environmental Assessment of Mixed Nuclear, Coal-Based.*
GIVE NAMES, DEPARTMENTS. AND OFFICIAL TITLES OF PRINCIPAL INVESTIGATORS OR PROJECT QIRECTORS AND ALL OTHER
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT. „.,..    ,.._,       „
                                         *and Hydroelectric Energy Systems
Project Director, H.  R. Hickey,  Chief, Applied Research and Education Staff, Division
  of  Environmental  Planning, TVA
Principal Investigator, Malcolm  Babb, Environmental Engineer, Division of Environmental
  Planning, TVA
NAME AND ADDRESS OF APPLICANT INSTITUTION
Tennessee Valley Authority
Division of environmental Planning
2bk 5oi Building
Chattanooga, TEi
     -  smir.n.,  Ha scarp.n
Division of Environmental Planning,
TVA
SUMMARY OF PROPOSED WORK - (1) Objective!, (2) Approach, C3) Current Plans and/or Progress (200 word* or lets. Omit confidential data).
   In the Smithsonian Science Information Exchange, summaries of work in progress are exchanged with government and private agenciea sup-
porting research and are forwarded to investigators who request such information. Your summary is to be used for these purposes.

   Output  Summary:

   The outputs of this project consist  of demonstrations of the desirability and
   practicality of using computer graphic techniques for improving  and facilitating
   the environmental impact assessment  of power generating facilities.  Current
   applications include:  (a) the use of interactive computer graphics for the
   analysis of the output of computerised models which predict the  dispersion of
   environmental residuals and (b) the  development of  a  system for  processing,
   analyzing and displaying geographically referenced  data for use  in power plant
   site  impact assessment.  An inventory of computer graphics applications has
   been  prepared.  Numerous demonstrations  have been implemented.   Most of the
   techniques developed  to date have been readily  accepted as a means of improving
   day-to-day assessment activities.
IDENTIFY PROFESSIONAL SCHOOL IN VOLVED {.Uodic.J,
    N/A
                                         SIGNATURE OF PRINCIPAL INVESTIGATOR
                        9/30/76
                                       FOR OFFICE USE ONLY
   SUPPORT METHOD i
      srAHCM GRANT
FUNDS OOLIGATuO  F.Y.    NO. OF FUTURE YEARS TENTATIVELY
                      ASSURED BEYOND CURRENT F.Y.
   $131,000     76
                                                PROJECT OFFICER
                                                  H. R.  Hickey
                                                RESPONSIBLE ORGANIZATION
                                                  Division of Environmental Planning  - TVA
                                                         STARTING DATE
          6/75
                       ESTIMATED COMPLETION
                       DATE
5/6/80
 EPA Form S760-1 (7*72)    REPLACES PHS FOttM tfaf. AND SI-SIE 76A WHICH MAY NOT QE USED.
                                         345

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                U.S. ENVIRONMENTAL PROTECTION AGENCY
                 NOTICE OF RESEARCH PROJECT
                                                                         Form Approved
                                                                       OMB No. D8-R0081
                                                               PROJECT NO. (Do not u»o thlg apace;

                                                               SSIE
       PREPARED FOR THE SMITHSONIAN SCIENCE INFORMATION EXCHANGE
                                                               EPA-IAG-D6-E762-BEG
  riTLE OF PROJEC1
                 Integrated A0Mara«nt: Socio-Economlc Consequences of Coal and Oil
                 Shale Develocmen£                                              ______
                                                        TORS OH PROJECT DIRECTORS ANO>LL OTHER
                                                            " 'Director, NaturalJl^sourc
GIVE NAMES, DEPARTMENTS, AND OFFICIAL TITLES OF Pj
PROFESSIONAL PERSONNEL ENGAGED IN THE PROJECT.
Economics Dlv.,  Economic Research Service, (KXS) USDA Washington, D.C.  zuzau  (.rrojecc
Director);Lloyd Bender, Agricultural Economist, Economic  Development Div., BRS,  USDA,
c/o Dept. of Economics,Montana State University, Bozeman,  Mt.  59715; Joseph Sane,
Agricultural Economist, Natural Raaonree Economics Division,  ERS, USDA, Washington, D.C,
20250
  NAME AND ADDRESS OF APPLICANT INSTITUTION
  Economic Research Service
  U.S. Department of Agriculture
  Washington,  D.C.   20250	
  SUMMARY OF PROPOSED WORK - (I) Objectives. (2) Approach, (3) Current Plan* and/or Progress (200 worda or less.  Omit confidential data).
                   nee Information Exchange, summaries of work in progress are exchanged with government and private agencie* »up-
                   •warded lo investigator* who request such information. Your «ummary !• to be ua«d for these purposes.
                    Describe current resource use in coal and  oil shale extraction and
porting research und are foi
(1)  Object*?
  (2)
    assess agricultural economic implications, resource competition and use, resulting
    from alternative future coal and oil shale development.   Estimate Impact Of  energy
    development in Northern Great Plains on employment, Income and population of rural
    communities and on local government finances and services, Including revenue po-
    tential.   Analyze interrelationships of local government expenditures to employment,
    population, income, age structure and other socio-economic variables.  $*aiuate
    coats of mined land reclamation and uses for land after  mining. Evaluate;inter-
    regional economic Implications and trade offa for agricultural and riral areas re-
    sulting from coal development.  Evaluate effects of increased water demand for coal
    development on agricultural  industries, environmental quality and rural resource use
    Approach—Gather data, describe current situation.  Make evaluations for local
    areas called homogeneous coal producing areas (HPA's), and aggregate these into
    regions and into an Interregional analytical system.   System will employ linear, or
    if appropriate, nonlinear programming under alternative  public policy constrains
    and objective functions to rationalize future or alternative allocation of extract!'
    reclamation, transportation  and energy activities among  HPA's and regiona.-
    Progresa—Reports In advanced manuscript stage: (a) State taxation of Mineral
    Deposits and Production; (b)  Northern Great Pianos Resources and Coal Development.
  IDENTIFY PROFESSIONAL SCHOOL INVOLVED (M
  rii-n(.,l. t-ff.)
            Hone
                                       FOR OFFlCEjUSE ONLY
     SUPPORT METHOD {C/i,-,-fc „„,
                                 1-9
                                                PROJECT OFFICER
                                                John R. Schaub
                                                RESPONSIBLE ORGANIZATION
                                                 USDA - ERS
unds  Estimate*
 ]$396,000
                76
                                                         STARTING DATE
3/76
                                                                          ESTIMATED COMPLETION
                                                                          DATE
                                                                         June  1979
 Funds approximate not for citation "* *N° SI-SIE 76A WHICH MSY NOT BE USED.
                                            346

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                                   TECHNICAL REPORT DATA
                            (Please read Instructions on the reverse before completing)
1. REPORT NO.
 EPA-600/7-77-004
2.
                              3. RECIPIENT'S ACCESSION NO.
4. TITLE AND SUBTITLE
                                                            S. REPORT DATE
                                                                         1Q 76
 Fiscal Year  1976/Health and  Environmental Effects
            	Research Program Abstracts	
                                                            6. PERFORMING ORGANIZATION CODE
7. AUTHOR(S)

 A. Gerard,  P .  Mavraganis,
               H
                              8. PERFORMING ORGANIZATION REPORT NO.
9. PERFORMING ORGANIZATION NAME AND ADDRESS
          AUTOMATION INDUSTRIES,  INC.
          VITRO Laboratories Division
           14000 Georgia Ave.
          fi-tlwr Spring, MH  20Q1Q	
                              10. PROGRAM ELEMENT NO.

                                    626     	
                              11. CONTRACT/GRANT NO.
                                    68-01- 2934
12. SPONSORING AGE.NCY NAME AND ADDRESS


 Nina  Rowe and Richard  Laska
 Office of Energy, Minerals, & Industry
      -o nf Tjpgtaarr-h anri Davelontnent WashinEtOn.  DC 20460
                              13. TYPE OF REPORT AND PERIOD COVERED
                              Abstracts Summary	
                              14. SPONSORING AGENCY CODE

                               EPA-ORD
15. SUPPLEMENTARY NOTES
  This report is  part of the Federal Interagency Energy/Environment Research and
  Development Program.
16. ABSTRACT
            This report includes SSIE(Smithsonian Science Information)Abstracts  per-
       taining to  the  FY 1976 Interagency  Energy/Environment  Research, Development
       and Demonstration Program being  coordinated and managed by EPA's Office of
       Energy, Minerals, and Industry.   The Abstracts are organized by major health
       and ecological  research categories.  This volume  includes research being
       accomplished  by EPA and its laboratories as well  as  a  number of other par-
       ticipating  agencies of the Federal  Government.
17.
                                KEY WORDS AND DOCUMENT ANALYSIS
                  DESCRIPTORS
                 b.lDENTIFIERS/OPEN ENDED TERMS  C. COS AT I Field/Group
       ABSTRACTS  •
       ENERGY
       ENVIRONMENTS
       ENVIRONMENTAL ENGINEERING
                  ENERGY/ENVIRONMENT
                  ENVIRONMENTAL Research

                  EPA PROGRAMS
06F
08H
10A
13B
18. DISTRIBUTION STATEMENT
          Unlimited
                                               19. SECURITY CLASS (ThisReport)
                                               	Unclassified	
                                                                          21. NO. OF PAGES
                 20. SECURITY CLASS (This page)

                       Unclassified
                                                                          22. PRICE
EPA Form 2220-1 (9-73)

 » U.S. GOVERNMENT PRINTING OFFICE: 1977-241-037:10

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