EPA
A Computer Code for
Cohort Analysis of
Increased Risks
of Death
-------
ORP Technical Report 520/4-78-012
A COMPUTER CODE FOR
COHORT ANALYSIS OF
INCREASED RISKS OF DEATH
(CAIRO)
John R. Cook
Byron M. Bunger
Mary K. Barrick
June 1978
U.S. Environmental Protection Agency
Office of Radiation Programs
Criteria & Standards Division
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FOREWORD
The Office of Radiation Programs carries out a national program to
evaluate the exposure of man to ionizing and nonionizing radiation and
to develop guidance, standards, and criteria for the protection of
public health the quality of the environment.
This report describes a more refined methodology than heretofore
u-sed for assessing the potential health impact of exposure to low levels
of ionizing radiation, as well as providing a means for comparing these
risks to those from other sources.
Readers are encouraged to bring to our attention any difficulties
encountered in their use of this code, as well as comments or
suggestions for its improvement. These comments should be directed to
John R. Cook, Federal Guidance Eranch, Criteria and Standards Division
(AW-U60), Office of Radiation Programs, U.S. Environmental Protection
Agency, Washington, D.C. ,20U60,
W.D. Rowe, Ph.D.
Deputy Assistant Administrator
for Radiation Programs (AW-U58)
111
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ACKNOWLEDGEMENT
The authors wish to express their gratitude to Christopher
B. Nelson and Philip A. Cuny for their assistance in developing the
CAIRO software, and to Beth Compher for her assistance in the
preparation of this manuscript.
IV
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Table of Contents
Page
FOREWORD iii
ACKNOWLEDGEMENT iv
1. INTRODUCTION 1
2. NCHS LIFE TABLES 3
2.1 Definition of NCHS Life Table Terms 3
2.2 Interpretation of Life Table Data 3
3. CAIRO LIFE TABLES 7
3.1 General Code Description ~>
3.2 CAIRO Version of Standard Life Table ~>
3.3 Calculation of Life Table Data 12
U. ANALYSIS OF INCREASED RISKS OF DEATH 16
U.I Accident Risk Analysis 16
<4.2 Radiation Risk Analysis 18
a. Latent & Plateau Periods 18
b. Radiation Risk Models 19
c. Exposure Stages 19
d. Induced Cancers 20
U.3 Radiation Risk Distributions 20
a. Fetal Stage Dose 20
1. Absolute Risk Model 20
2. Relative Risk Model 25
b. Child or Adult Stage Dose 28
1. Absolute Risk model 28
2. Relative Risk model 28
1.14 Combined Accident and Radiation Risk Analysis 29
5 . CAIRO SUMMARY TABLES '. 31
5.1 Normalization of Output Data 31
5.2 Calculation of Output Data 31
5.3 Premature Death Subtotals 32
6. REFERENCES 33
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APPENDIX A: 34
Input Requirements 35
User Aifls 33
Glossary 39
APPENDIX B: 44
Sample Problems 46
Reference Table Data 93
Cancer Mortality Data 99
Code Listing 100
VI
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1. INTRODUCTION
An important consideration in the development of radiation
protection guidance and standards is -the analysis of the health risk
incurred by the individuals in an exposed population. The most serious
somatic risk confronting individuals exposed to radiation is death from
an induced cancer. These cancers, in general, do not develop until many
years after exposure. The delay permits other causes of death to
intervene and take the lives of -those otherwise destined to die from
cancer. Thus two considerations must be accounted for in radiation risk
analysis: the temporal distribution of induced cancers and competing
risks of death.
A computer code, CAIRD (Cohort Analysis of Increased Risks of
Death), has been developed to aid risk analysis by calculating the
number of premature deaths and loss of years of life produced in a
hypothetical population after exposure to a given risk situation. The
number of premature deaths is estimated using life tables. !^ life table
methodology has been used recently to determine the risk/benefit ratio
of mammography. » Although the CAIRD code can, be used with any set of age
specific probabilities of death, the 1969-71 U.S. population data, as
reported by the National Center for Health Statistics (NCHS) in its
decennial life tables, have been used in the CAIRD calculations
performed to date.2
The NCHS life tables contain age specific probabilities of death
from all causes for various population groups, as well as associated
.survival and longevity information. They are useful for risk analysis
because they provide a baseline or reference for the risk of death from
all causes for any given age. The effect of an increased risk may be
calculated by incorporating the corresponding increase in the
probabilities of death into generated life tables and comparing the
results with reference life tables.
The CAIRD code generates modified life tables and estimates the
impact of the increased risk through several numerical comparisons with
the appropriate reference life tallies. These comparisons yield: (1) the
number of persons dying prematurely due to the increased risk of death;
(2) the total number of years of life lost by those dying prematurely;
(3) the average number of years of life lost for those dying
prematurely; and (U) the decrease in the population's life expectancy at
birth.
One of CAIRO'S frequent applications is in estimating the number of
radiation induced cancer deaths that would result from exposing an
initial population of 100,000 individuals (cohort) to an annual
radiation dose. Either the absolute or relative risk models, as
developed by the National Academy of Sciences' Committee on the
Biological Effects of Ionizing Radiation (BEIR report), may be used to
estimate the risk of radiation induced cancer death.3 The effects of an
incremental accident risk on the cohort may also be calculated, either
separately or in combination with radiation risk. The code may be used
for risk analyses involving the male, female or total population, the
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latter being a combination with the same sex ratio as that of the U.S.
population.
For each risk situation analyzed, the CAIRO code generates a
summary table which documents the input data and contains the results of
the comparisons with the reference life tables. In addition to the
summary table, the generated life table, as well as two tables which
contain the age distribution of deaths due to radiation risks, may be
produced.
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2. NCHS LIFE TABLES
2.1 Definition of Standard Life Table Terms
A life table for the total population, prepared by the
National Center for Health Statistics, is reproduced in Table I. The
example shows the overall mortality experience for the U.S. population
during 1969-1971, regardless of sex, race, national origin, etc. A
brief description of columns in the table follows:
1) Age interval (x to x+t) - period of life between the
specified ages.
2) Proportion dying (tqx) - proportion of the population
alive at the beginning of the age interval who will die before reaching
the end of the interval. This may also be considered the probability of
death for each age interval.
3) Number surviving (lx) - the number of persons, starting
with a population of 100,000 live births, who will survive to the
beginning of the specified age interval.
in the
U) Number dyinq (t^x^ ~ tne number of persons dying
age interval.
5) Average number years lived (tLx) - the average number of
person-years of life lived in the age interval, assuming deaths are
uniformly distributed across the age interval.
6) Total years of life (Tx) - the number of person-years of
life remaining to the persons surviving at the beginning of the age
interval.
7) Average remaining lifetime (e ) - the average number of
years of life remaining to persons surviving at the beginning of the age
interval.
2 . 2 Int erpretation of Li.f e TabJLe Da ta
The life table data in Table I may be used to define either a
single cohort or a stationary population model. The single cohort
interpretation assumes that there is one cohort of 100,000 persons, all
of whom are simultaneously liveborn. During the first year of life, the
cohort is exposed to the probability of death for 0-1 years-olds as
listed in column 2. The product of this probability and the cohort size
(column 3) yields the number of persons in the cohort that die during
the 0-1 age interval (column H) . These deaths are subtracted from the
cohort size to generate the number of survivors that proceed to the
succeeding age interval, which is entered in the third column for the
following (1-2) age interval. The years of life lived in the interval
(column 5) is equal to the average of the numbers surviving at the
beginning and end of the age interval. Finally, the total number of
years of life remaining to the survivors entering the age interval is
-------
Table I
Life Table for the Total Population, U.S. 1969-71
AGE INTERVAL
PF.PIQD OF L IFE
BETWEEN TWO AGES
< 1 )
* to x •* t
DAYS
YEARS
A9-50
PROPOFTI ON
DYING
PROPORTION
OF PERSONS
AL I VE AT
BEGINNING OF
AGE INTERVAL
DYING DURING
INTERVAL
,,.
O.JJ674
.004H2
.00147
.31513
.02002
.30125
.00086
.00069
.30057
.00051
.00043
.00039
.0003-
.00031
.00030
.OOC35
.030-0
.00063
.00082
.00101
.301 17
.00126
.00134
.00140
.00147
.00152
.0015;
.00151
.00147
.30143
.00142
.00144
.00149
.00155
.00163
.00172
.00183
.00195
.30209
.00225
.00244
.33266
.00290
.00314
.30341
.00370
.00404
.00443
. 004 6-
.00526
.00574
.00624
.00678
CF 1 00,000 BP*N AL IVE
NUMBEF
LIVING AT
BEGINNING (IF
AGC INTERVAL
I 31
/.
1 00,330
99,126
96,646
98,503
100, DO?
97,996
t, 97,376
* 97, 792
97,724
97,6o9
97, e 19
97,573
97.531
97,494
9 7 , 4 6 3
97,430
97,401
97,367
97,322
97,26!
97, 181
97,083
96,970
96,846
96,716
= L, 580
96,436
96.292
96.145.
96,000
95,859
95,721
95,586
95,448
95,307
95,158
95,003
94,840
94,666
94,482
94,266
94,373
93,843
93.593
°3,322
93,328
92,712
92,368
91 ,995
= 1 ,567
91 .144
90,662
90,142
89,579
NUMBER DYING
3U= ING
AGE INTERVAL
(41
,-.
674
476
1-5
5J5
2,032
12:
84
bf
56
49
-c
42
37
34
29
34
-5
61
80
96
113
124
130
136
142
146
147
145
141
138
135
138
141
149
155
163
1 74
184
197
212
230
253
271
294
316
34-
373
438
44 :
-82
520
607
S T A T 1 G '.' i - Y
IN THE Af,f
INTER VSL
(51
,,.
272
1,626
5. t-71
90, 714
98. 263
97, =27
97, 634
97, 756
97,f.96
97,643
97. 59t
97, 553
97,512
97,477
97, 4-5
97, 384
97, 3-4
97,221
97, 132
97. C?7
96,936
96.781
9c. 646
96, f-lC
96, 3o'j
96.21P
96.072
95.9J9
95,7=0
95. b54
95.5 17
95.377
95,233
95,060
94,922
94, 753
94, 574
94, 3S4
94. 179
93. 95S
93. 716
93.457
93, 175
92, 870
92. 540
92. 182
9! , 791
SI . 'i5
90, =0i
90, 4j;.
69.861
S9.275
CPULiT ION
AND ALL
S'JBSE PL'E NT
«GE INTERVALS
1 1.1
£VEcir,lr ' E " i 1 '. -
1 Nj L I I f T I M •"
f-Uu.fE- PF
YF AC £, 0- LIFE
(7 I
r ?_
7,074,927
7,074.6? 5
7.C73.C29
7,0( 7,355
7, J7-.927
t.,^7t .644
t, 676, 7C>7
6,:ro,673
t, 66?, 11 5
6,565,419
6,467, 77c.
( , 390. IE 3
t-,292,62 7
(. ,000.193
5 , 9 0 2 , 7 7 F
5, 805, J94
5, 706, Of. 0
5,610.758
'., 51 3,537
5,41 r,,405
5,319,378
5,222,47C'
f . 125, oS9
:•, 329,04 :
4 , £3b, 16t
4, 739,946
4,6-3, 876
4, 547, =4 7
4,452,157
4,356,503
4, 2tO,9B6
4, 165, 009
4,070,?7-j
3,975.2=6
3,560, 374
3- 766,621
3,6=1 ,0-7
3, 596,663
3, 502,464
3,408,f?C:
3, 31-, 808
3,221 ,35 1
3, 128. 1 7o
3,035,306
2,942,7e6
2 . BSD.I-f-
2, 756, 7-=
? , 6 1 7 , - r
2,466,12
2 . 39c . 26
7C. 75
7! . ?'
71. 70
71.7;
7 "r . 7 •
7 ! . 1 =
7 J . 2 c
t S . "* =
1 7 . 4 :-
C !• . - 0
C- 4 . '• 2
63. 5-
!' 1 .56
m
t -. ^.q
f) t . 7 :•
f-f>. f -
r, -. ^ r '-
M:"
-3. 71
- ~ . 7 7
41 .(•-
.0.92
3°. 9 =
? - . •:• 7
7 f . I 5
37.23
35.42
;-.52
53.C-3
3 ? . 7 4
:-I.RC,
?.:.=9
70.12
: s . ? 7
^ ~ . li-
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Table I cont'd
Life Table for the Total Population, U.S. 1969-71
AGE INTERVAL
PERIOD OF LIFF
BETWEEN TWO AGES
( 1 >
I to X + (
YEft»S — CON.
74-75
76-77
PROPORTION
DYING
PROPORTION
OF PERSONS
ALIVE AT
BEGINNING OF
AGE INTERVAL
DYING DUP ING
INTERVAL
121
.«.
. 3073B
.0080^
.00876
..10957
.010*3
.01136
.01236
.01341
.01452
.0 1 570
.01695 ^
.01629
. D 1 S74
.02133
.02306
.02695
. 029 16
.03152
.03400
.03943
.04266
. 04644
.05075
.05552
. 06060
. 06596
.07153
. 07741
.08394
.09122
.09692
.10695
.1 1548
. 12561
. 1 3748
.14979
.16158
.17292
. 1 8502
. 19888
.21363
.22670
.24336
.25745
.26959
.28024
.28977
.29869
. 30696
. 3 1461
.321 67
.32617
.33414
.33960
.34460
.34917
.35333
.35712
OF 100,000
NUMEF.P
LIVING AT
BEGINNING OF
AGE I NT EFVAL
(3)
lt
.
88,972
68,315
87,605
86,836
86, 007
85,110
84 , 1 42
63,103
Rl ,988
80, 798
I 79,529
78, 181
76,751
75,236
73,631
71 ,933
70, 13C
68* 246
66.254
64 , 166
61,984
59,715
57, 360
54.913
52.363
AS. 705
46 .946
44,101
41, 192
36 . 245
35,285
32.323
2°. 375
26. 469
23,638
20,908
16,282
15,769
1 3 ,407
11,240
9,297
7,577
6,070
4.773
3,682
2.786
2,066
1.511
1.087
772
542
375
257
L75
1 17
78
52
34
22
14
BOPN ALIVE
NUMBER DYING
DUPING
AGE INTERVAL
(41
,rf.
657
710
767
831
897
968
1. 039
1,115
1,190
1 .269
1,348
1.430
1,515
1, 605
1,698
1 , 794
1, 893
1 , 992
2,068
2, 182
2 , 269
2, 355
2,447
2.550
2.658
2.759
2. 645
2.909
2. 947
2 , 960
2, 962
2, 948
2.906
2, 831
2, 730
2, 626
2, 513
2, 362
2,167
1.943
1 * 720
1, 507
1 , 297
1,091
896
718
557
424
31S
230
S67
118
82
58
39
26
18
12
e
5
STATIONARY
IN THE AGE
INTERVAL
15)
,*.
86, 644
67, 960
87, 221
86,422
85, 558
84,626
83,623
82.545
81, 393
80. 163
78, 656
77,466
75,994
74,433
72. 782
71.036
69. 192
67, 250
65, 210
63.074
60. 849
58, 538
56, 136
53,638
SI. 034
46, 325
45, 523
42, 647
39,716
36, 766
33, 803
30, 849
27,922
25,053
22,273
19, 595
17, 025
14, 588
12, 324
10, 268
6, 437
6, 823
5,422
4, 227
3, 234
2,427
1, 789
1, 300
929
657
459
316
216
146
98
65
42
28
18
12
>P°ULATION
IN THIS
AND ALL
SUBSEQUENT
AGE INTERVALS
(61
Tf
2,306,987
2.218,343
2.133,383
2.043,162
1.956,740
1,871,182
,766,556
,702,933
,620.366
.538,995
,458,832
,379,976
,302, 510
.226,516
,152,083
,079, 301
,008.265
939,073
871,823
806,613
743,539
662,690
624,152
568,016
514,378
463,344
415,019
369,496
326,849
267,131
250,365
216,562
185,71 3
157,791
132,738
110,465
90,870
73.845
59,257
46,933
36,665
28,228
21 ,405
15,963
1 1,756
8,522
6, 095
4,306
3,006
2,07 7
1*420
96 1
645
429
283
185
120
78
50
32
AVERAGE OEMAIN-
I»JG LIFETI-E
AVERAGE
NUKBEP OF
YEARS OF LIFE
REMAINING AT
PEG I NN1NG OF
AGE INTERVAL
(71
tf
25.93
25. 12
24.32
23.53
22.75
21.99
21.23
20.49
19. 76
19.05
18.34
17.65
16.97
16.30
15.65
15.00
14.38
13.76
13. 16
12.57
12.00
11.43
10.88
10.34
9.82
9.32
8.B4
8.38
7.93
7.51
7. 10
6.70
6.32
5.96
5.62
5.28
4.97
4.68
4.42
4.18
3.94
3.73
3.53
3.35
3.19
3.06
2.95
2.85
2.76
2.69
2.62
2.56
2.51
2.46
2.41
2.37
2.34
2.30
2.27
2.24
-------
given in column 6, and column 7 lists the average years of life left, or
life expectancy, for the survivors entering the age interval.
The survivors from each age interval proceed on to the
succeeding one until the last reported age interval, 109-110, is
reached. The years of life remaining for those who survive beyond age
110 are included in this age interval.
Throughout its "life" the cohort is subjected to the average
probabilities of death calculated for the U.S. population during the
years 1969-71 only. Thus the results from the life table analysis
should be viewed as if the cohort lived its entire existence instantly,
using the mortality data from that three year period. The life tables
should not be interpreted as predicting future effects in a real
population, since this is dependent on many unknown quantities,
including future death probabilities. They are useful, however, for
indicating relative changes which might occur under prevailing mortality
c ond i ti on s.
In a stationary population, 100,000 persons are assumed to be
born every year and the proportions dying experienced by each age group
is taken to be that listed in column 2. This yields an equilibrium
population in which the number of people at a given age does not vary
from year to year. The interpretation of life table data as a
stationary population is potentially useful for certain risk situations,
but is not advantageous for^calculation of risk to the individual and
therefore is not used in the code.
-------
3 . CAIRD LIFE TABLES
3.1 General Code Description
A simplified flow diagram of the process used in CAIRD to
generate life tables is shown in Figure 1. The flowchart details the
major steps used to calculate the effects of increased risks of death.
In order of execution, these steps are:
1) calculation of age specific probability of death from
radiation risk
2) calculation of age specific probability of death from
accident risk
3) generation of the modified life table
U) calculation of radiation induced deaths by age, stage of
life, and cancer type.
5) comparison of case results with reference data
6) output of results
'v
The first two steps calculate the increase in the probability
of death that corresponds to the increased risk of death resulting from
exposing the population to a given risk situation. The incremental
probabilities are added to the reference probability data, and a
modified life table is generated. In the fourth step, calculations may
be performed which categorize radiation induced deaths by type of cancer
cr by the stage of life (fetal, child, or adult) during which the dose
is received, or both. The comparisons with the reference table are than
performed followed by output of the results.
If the code is run for the case of no increased risk of death,
the result is simply a facsimile of the NCHS life table (Table II) . A
comparison between the CAIRO version of the life table .and Table I
reveals certain modifications that have been made to accommodate
analysis of incremental risks.
3.2 CAIRD Version of an NCHS Life Table
The CAIRD life table includes three columns not found in the
reference life table. The first of these is the incremental probability
of death (IXR) column, which shows the total increment to the reference
probability of death from increased risks. The sum of this increment
and the reference probability is shown in the total probability (TQXR)
column. The third additional column is comprised of the number of
deaths which are attributable to the increased risks of death (IXRLXR).
Since the example shown in Table II does not include an
increased risk of death, the IXR and IXRLXR columns contain zeros. The
total probability of death (TQXR) column is simply equal to the
-------
START
READ CASE
DATA
GENERATE MODIFIED
LIFE TABLE
COMPARE RESULTS
WITH REFERENCE DATA
WRITE SUMMARY
TABLE
READ RADIATION
RISK DATA
READ CANCER
MORTALITY DATA
CALCULATE CANCER
PROBABILITY OF DEATH
STORE PROBABILITIES
BY AGE, STAGE AND CANCER
READ ACCIDENT
RISK DATA
CALCULATE ACCIDENT
PROBABILITY OF DEATH
CALCULATE PROPORTION
OF RADIATION DEATHS
WRITE LIFE TABLE
WRITE STAGE TABLE
WRITE CANCER TABLE
Figure 1
CAIRO Flow Diagram
-------
TABLE II
GENERATED LIFE TABLE FOR THE GENERAL POPULATION* UNITED STATES. 1969-71
X TO X*T
VEARS
0- 1
1- 2
2- 3
3- 4
1 5- 6
6- 7
7- 8
8- 9
9- 10
10- 1 1
11- 12
12- 13
13-14
14-15
15- 16
16-17
17-18
18- 19
19- 20
20- 21
21- 22
22- 23
23- 24
24- 25
25- 26
26- 2 7
27- 2I»
2B- 29
29- 30
30- 31
31- 32
32-33
33- 34
34- 35
35- 36
36- 37
37- 3B
3H- 39
39- 40
TQX
0.0200200000
0.0012449230
O.OG08582290
0.0006953530
0.0005730420
0.0005017000
0.0004712200
0.0004304470
0.0003793670
0.0003487390
0.0003078190
0.0002976500
0.0003490720
0.0004621690
0.0006267850
0.0008225290
0.0010064280
0.0011639520
0.0012787460
0.0013423370
0.0014061790
0.0014702840
0.0015139260
0.0015266070
0.001508139C
0.0014687500
0.0014396140
0.0014103490
O.OC1443726C
0.0014772440
0.0015633690
0.0016286700
0.0017157350
0.001834f-6<>0
0.0019436760
0.00?0fi5r)53c
0.0026640740
0.0028955160
IXR
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0-0
0.0
0.0
0.0
0.0
o.o
0.0
0.0
0.0
0.0
0.0
O.Q
0.0
0.0
0.0
O.o
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
IQXR
0.0200200000
0.0012449230
0.0008582290
0.0006953530
0.0005730420
0.0005017QOO
0.0004712200
0.0004304470
0.0003793670
0.0003467390
0.0003078190
0.0002976500
0.0003490720
0.0004621690
0.0006267850
0.0008225290
0.0010084260
0.0011639520
0.0012787460
0.0013423370
0.0014061790
0.00147C2840
0.0015139260
0.0015266070
0.0015081390
0.0014687500
0.0014396140
0.00 141 034 SiO
0.0014437260
0.001477244Q
0.0015633690
0.00162F8700
0.0017157350
0.001b34669o
0.0019436760
0.0022485020
0.00?«i449100
0.0026C40240
0.0028955160
LXR
130000.0000
97998.0000
97876.QOOO
97792.0000
97724.0001
97668.0001
97619.0001
97573.0000
97531.0000
97494.0000
97460.0000
97430.0000
97400.9999
97367.0000
97322.0000
97261.0000
97181.0000
97083.0000
96970.0000
96846.0000
96716.0001
96560.0000
96438.0000
96292.0000
96145.0000
9tOOO.OOOO
95859.0000
95721-0000
95586.0000
95446.0000
95307.0000
95158.0000
95003.0000
94840.0000
^4666.0000
94482.0000
942B5.0000
94073.0000
93H43.0000
93593.0000
DXR
2002.0000
122.0000
84.0000
68.0000
56.0000
49.0000
46.0000
42.0000
37.000C
34.0000
30.0000
29.0000
34.0000
45.0000
61.0000
80.0000
98.0000
113.0000
124.0000
130.0000
136.0000
142.0000
146.0000
147.0000
145.0000
141.QOOO
138.0000
135.0000
13H.OOOO
141.0000
149.0000
155.0000
163.0000
174.0000
1^4.0000
1V7.0000
212.0000
230.0000
250.0000
271.0000
TLXR
98999.0000
97937.0000
97834.0000
97758.0000
97696.0001
97643.5001
97596.0000
97552.0000
97512.5000
97477.0000
97445.0000
97415.5000
97384.0000
97344.5000
97291.5000
97221.0000
97132.0000
97026.5000
96909.0000.
96781 .0000
96648.0000
96509.0000
96365.0000
9621B.5000
96072.5000
95929.5000
95790.0000
95653.5000
95517.0000
95377.5000
95232.5000
95080.5000
94921 .5000
94753.0000
94574.0000
94383.5000
941 79.0000
93958.0000
93718.0000
93457.4999
TXR
7075647.4998
6976648.4998
6878711.4998
6780877.4998
6683119.499 7
6585423.4997
6487779.9996
6390183.9995
6292631.9995
6195119.4995
6097642.4995
6000197.4995
5902781.9995
5805397.9995
5708053.4996
5610761.9996
5513540.9996
5416408.9996
5319382.4996
5222474.4995
5125693.4995
5029045.4995
4932536.4994
4836171.4994
4739952.9994
4643860.4994
4547950.9995
4452160.9995
4356507.4995
4260990.4995
4165612.9995
4070 3HO. 4995
3975299.9996
3880378.4996
3785625.4996
3691051 .4996
3596667 .999t
3502488.9996
3408530.9996
3314812.9997
EXR
70.756479
71.191744
70.279859
69.339798
68.387699
67.426624
66.460218
65.491314
64.519302
63.543598
62.565591
61.584702
60.602889
59.623877
58.651215
57.687666
56.734763
55.791529
54.855961
53.925557
52.997369
52.071293
51.147229
50.224022
49.300047
48.373755
147.444173
'46.511852
45.576837
44.642009
43.707314
42.774969
41.843942
40.914999
39.989283
39.066187
38.146768
37.231607
36.321633
35.417318
IXRLXR
0.0
0.0
O.D
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
. 0.0
Q.O
0.0
0.0
0.0
0.0
0.0
0.0
o.o
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
o.o
0.0
0.0'
0.0
0.3
0.0
-------
TABLE II (cont.)
GENERATED UpE TABLE FOR THF GENERAL POPULATIUN! UMTfct) SIA7ES, 1969-71'
X TO X»T
YE ARS
40-41
41- 42
42-43
43- 44
4/,_ <,5
45- 46
46-47
',7- 4C.
48- 49
49- 50
50- 51
51- 62
52- 53
53- V.
54- 55
55- 50
56- 57
5 1- 5 P
5H- 59
59- 60
60- 61
6 I- 6?
62-63
63- 6'.
64- 65
65- 66
66- 67
67- 6C
68- 69
69- 70
7 0- 71
71- 72
7?- 73
73- 74
7*,- 75
75- 76
76- 7 7
77- 78
7H- 79
79- 80
TO*
0.0031503H20
0.0033968270
0.0037104150
0.0040381950
0.0044350240
0.0048369310
0.0052003350
0.0057355890
0.0062457010
0.0067761420
0.0073843460
0.0000394040
0.0087552080
l>. 00 956954 30
0.01 042930 40
0. 01137351 70
O.U1234B1 /30
0.0134 170(15 o
U. OlV.il 431 90
0-0157058340
0.0169497920
O.OIU290B390
0. 0197391560
0.0213328730
0.0?3060939o
0.0249398750
0.0269892640
0.0291885240
0. 0315150 7BO
0.0340055480
0.03660622 10
0.0394373270
0.0426603900
Q. 0^64 3709 10
0.0507610340
0.0555074940
0.0606015420
0. 06596222 30
0.071543olHc
0.0 773957380
IXR
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
O.p
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
TCXK
0.0031503620
0.0033968270
0.0037104150
C. 0040 ?8 1950
0.0044350240
0.0048369310
0.0052f.5008
4)066 16. 500B
743541.5008
682692.0008
624154.5008
568018.0008
514380.0007
463346.0007
415020.5006
369497.0006
326850.5005
287132.0005
EXR
34.518715
33.626225
32.739133
31.859199
30.986347
30.122157
29.266134
28.419068
27.580124
26.750321
25.929410
25.118587
24.318110
23.526464
22.750985
21. 985*95
21.232672
20.491664
19.763764
19.047463
18.343434
17.651092
16.970645
16.302309
15.646766
15.004310
14.375296
13.760169
13.158651
12.570777
11.995701
11.432504
10.681355
10.343962
9.823349
9.321919
8. 840360
8.378427
7.934605
7.507700
IXRLXR
0.0
0.0
0.0
0.0
0.0
0.3
0.0
0.0
0.0
0.9
0.0
0.0
0.3
0.0
0.0
0.0
0.3
0.0
0.0
0.0
0.0
0.0
0.0
0.3
0.3
0.0
0.3
0.3
0.0
0.0
0.0
0.3
0.0
0.0
0.3
0.0
0.0
0.0
0.0
0.0
-------
TAnr.F. ii (cont.)
GENERATED LIpE TABLE FOR THE GENERAL POPULATION: UNITED STATES, 1969-71
X TO X«T
YEARS
80- Bl
81- 8?
82- 83
•- 83- 84
84- 65
85- 86
86- 87
87- 88
88- B9
89- 90
; 90- 91
91- 92
92- 93
93- 94
94- 95
95- 96
96- 97
. 97- 9fl
98- 99
99-100
100-101
101-102
102-10?
103-104
104-105
105-106
106-107
107-108
108-109
109-110
TQX
0.0839450190
0.0912044050
0.0989276600
0.1069553060
0.1154920040
0.1255978570
0.1374576090
0-14978755BC
0. 1616319830
0.1728647690
0. 1650059160
0. 1988913B20
0.2136738060
0.2285774150
0.2433460080
0.2577171570
0.2693423600
0.28060HB6HO
0.28978840HO
0.2979274610
0. 3081160810
0.31466666 70
0.3190661480
0. 331^285710
0.3333333330
0.3333333330
0.3461538460
0.3529<,1 1760
0.3636363640
0.35 714285 10
1XR
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0-0
0.0
O.Q
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
lOXR
'
0.0639450190
0.0912044Q50
0.0989276600
0.1069553060
0.1154920040
0.1255978570
0.1374576090
0. 14978 755BO
0.1616319830
0.1728647690
0.1850059160
0.1988913820
0.2136738060
0.2265774150
0.2433460080
0.2577171570
0.2693423600
0.28060886bo
0.2B978b40BO
0.2979274610
0.30bllB0810
0.3146666670
0.3190661480
0.33 142H5710
0.3333333330
0.3333333330
0.3461538460
0.3529411760
0. 3636 3< 3640
0.357142H57()
LXR
35285.0000
32323.0000
29375.0001
26469.0000
23638.0000
20908.0000
lb2R2.0000
15769.0000
13407.0000
11240.0000
9297.0000
7577.0000
6070.0000
4773.0000
3682.0000
2786*0000
2068.0000
I5H.OOOO
1087.0000
772.0000
542.0000
375-0000
257.0000
175.0000
117.0000
78.0000
52.0000
34.0000
22.0000
14.0000
OXR
2962.0000
2948.0000
2906-0000
283 1.0000
2730.0000
2626.0000
2513.0000
2362.0000
1 167.01*00
1943.0000
1720.0000
1507.0000
1297.0000
1091.0000
b96.0000
710.0000
557.0000
<,?<,. 0000
315.0000
230.0000
H7.0000
life. 0000
82.0000
58.0000
39.0000
26.0000
lb.0000
12.000C
fc.OOOO
5.0000
TLXR
33804.0000
30849.0001
27922.0001
25053.5000
22273.0000
19595.0000
17025.5000
1 4588.0000
12323.5000
10268.5000
B437.0000
6823.5000
5421.5000
4227.5000
3234.0000
2427.0000
1789.5000
1299.0000
929.5000
657.0000
458.5000
316.0000
216.0000
146.0000
97.5000
65.0000
43.0000
28.0000
18.0000
11 .5000
TXR
250367.0004
216563.0004
185714.0003
157792.0003
132736.5002
110465.5002
90870.5002
73845.0001
59257.0001
46933.5001
36665.0000
28228.0000
21404.5000
15983.0000
11755.5000
8521 .5000
6094.5000
4305.0000
3006.0000
2076. 500C
1419.5000
961 .0000
645.0000
429.0000
283.0000
185.5000
120.5000
77.5000
49.^000
31 .5000
EXR
7.095565
6.699966
6.322179
5.961389
•5.615471
5.283408
4.970490
4.662922
4.419855
4.17557B
3.943745
3.725485
3.526277
3.3<,6628
3.192694
3.056686
2.947050
i.8491o7
2.765409
2.689767
2.619004
2.562667
2.509728
2.451429
2.418803
2.376205
2.317306
2.27941?
2.250000
2.250000
IXRLXR
0.9
0.3
0.3
0.0
0.0
0.0
0.0
0.0
O.o
0.0
0.0
0.0
0.3
0.0
0.0
0.3
0.3
0.0
0.0
0.0
0.0
0.0
0.3
0.3
0.0
0.0
0.0
0.3
0.0
0.0
-------
reference probability of death (TQX). In cases in which an increased
risk of death is included, the IXR risk data are supplied to the main
program by subroutines. A general description of the algorithms used in
these subroutines is given in the next section.
Another dissimilarity between the NCHS and CAIRD life tables
lies in the additional decimal places used in the CAIRD tables. The
extended decimal fields are available because the tq^ data, from which
all the column data are derived, have been recalculated to nine decimal
places in the CAIRD version using the standard lx and dx data:
_a ' = d
t 'x x
X
The recalculated data are accurate and significant to four decimal
places. The remaining decimal places are artifical and have no real
significance, but are used arbitrarily to represent the reference
probabil-i ties of death to nine places because in certain instances, the
incremental probabilities of death are quite small. It is assumed that
any resulting inaccuracy in the life table calculations does not
significantly effect comparisons of results between different risk
si tua ti on s.
For each of the three populations (male, female, and total) , a
CA.IRD life table has been generated without any incremental risk using
the recalculated data. These tables are used as the source of fcqx , IK
and Tx data in all generated tables, and are henceforth referred to as
the reference life tables.
The CAIPD table differs from the NCHS table in two other
respects- The first values for the TLXR and TXR columns are not in
r"•.esc- agreement with their reference table counterparts, while the rest
01 the data arc. The difference arises because the first age interval
it given special consideration in the reference table. Since infant
..•ortality rates are relatively high, the first year of life is broken
dowr in'-o quarterly time periods and the life table data are calculated
r- . -'- ratsiy for ^ach period. The overall results for the four periods
are used in the first age interval of the reference life table. The
CAIRD table does not use this added sophistication, and the first age
interval is treated in the same manner as all others.
The small differences arising between some of the other
columns are attributable to the additional decimal places used in the
CAIRD table and round-off error. CAIRD life tables for cases including
an increased risk of death have the same basic features as those
described above, and differ from reference tables in the same respects.
3.3 Ca_l cualtion of Life Table Data
The CAIRD life table data are calculated in the code's main
section. The table data are handled as elements of 2 arrays: a 2 x 110
integer array for the age interval data, and a 9 x 110 real number array
for the life table data. The array data are produced by an iterative,
two st°p process. 3
12
-------
During the first step, the following data are calculated or
assigned progressively, from a user selected age (NORMAG see Glossary)
through age 110. The equations provided below are equivalent to the
code statements, but are written with the more tractable column heading
potation. The subscript (i) denotes age in all equations.
1) Age intervals
Intrvl2(i) = i (1)
Intrvll(i) = Intrvl2 (i) - 1 (2)
2) Reference probability of death (TQX)
The reference probability of death data for the
population under study must be supplied to the code. These
probabilities express risk of death for those surviving at the beginning
of an age interval. They are incompatible for addition to the mortality
rates which result from increased risks of death, since mortality rates
express risk to those surviving at the midpoint of the age inteval. The
problem is reconciled by converting the reference probabilities of death
to mortality rates, which are temporarily stored as values of REFMOR:*
REFMOR = tqx (3)
1.0 - 0.5 tqx^
The mortality rates due to increased risk are supplied to
the main program by the risk subroutines:
INCMOP = mortality rate (i) (U)
The reference mortality rates are added to the
incremental risk mortality rates to obtain the total mortality rate.
Once the mortality rates are added, the respective components must be
converted to probabilities of death because the remaining life table
calculations require the probability format. The fraction of the total
mortality which corresponds to the reference life table risks are
converted to probabilities of death as follows:
TQX(i) = REFMOR (5)
1.0 + 0.5 (REFMOR + INCMOR)
3) Incremental probability of death (IXR)
The remaining fraction of the total mortality corresponds
to the increased risk of death. The conversion equation to death
probability is:
IXR(i) = INCMOR (6)
1.0 + 0.5 (REFMOR + INCMOR)
-------
The total probability of death is the sum of the
reference and incremental death probabilities:
TQXR(i) = TQX(i) + IXP. (i) (7)
U) Total number dying (DXR)
The number of individuals dying from both reference and
incremental probabilities of death is next in the calculat:on sequence:
DXR(i) = TQXR(i) x LXR(i) (8)
The first value of LXR is taken from the reference table
data.
5) Number surviving (LXR)
The number surviving is calculated for the succeeding
(i+1) age interval by subtracting the number of deaths occurring in the
current age interval from the number of survivors entering the current
age interval:
LXR (i + 1) = 'JJCR(i) - DXR(i) (9)
6) Average number surviving (TLXR)
The average number surviving in an age interval is the
average of the number surviving at the beginning of the current and
succeeding age intervals. This quantity may also be regarded as the
number of person-years of life lived during the age interval:
TLXR(i) = LXRfil + LXRfi+11 (10)
2
7) Number of premature deaths (IXRLXR)
Since the number of deaths in the cohort remains constant
at 100,000, there can be no "excess" deaths. Incremental risks
therefore result in deaths that simply occur before they would have had
there been no increased risk of death. Fractional deaths are carried
through all calculations.
IXRLXR(i) = IXR(i) x LXR(i) (11)
The data for the two remaining colums, TXR and EXR, are
calculated during the second life table generation step. These
calculations are performed regressively from age 110 to the user
selected age because the two quantities begin with the final (age = 110)
values for TLXR and LXR, respectively.
14
-------
8) Years of life remaining (TXR)
The years of life remaining to the survivors in the 109-
110 age internal is the sum of the years of life lived during that
interval (agp = 110 entry for TLXR) and all subsequent age intervals.
The latter component is taken from the reference table data:
TXR (110) = TLXR(110) + years lived after age 110 (12)
The remaining TXR data are calculated as follows:
TXR(i-l) = TLXF(i-l) + TXR(i) (13)
9) Average years of life remaining (EXR)
The last table column calculated is the average years of
life remaining to the cohort, or its life expectancy, and is th°
quotient of the years of life remaining and the number of survivors:
EXR(i) = TXR(i) (1U)
LXR (i)
15
-------
U. ANALYSIS OF INCREASED RISKS OF DEATH
The preceding sections have outlined the structure and content of
NCHS life tables as well as the equations used in the code for
generating modified life tables. While generation of life tables is the
core of the code, the majority of the non-output sections is devoted to
managing, calculating and storing the incremental risk data.
This section deals with the algorithms used to generate the age
distributed mortality rates that result from exposing the cohort to risk
situations. The two major risk categories which can be analyzed using
CAIRO will be discussed individually first, follwed by an example whi-h
C9mbines risks from both categories.
U.1 Accident R^sk Analysis
There are, of course, many different types of risks of death.
For purposes of this analysis, these risks may be grouped into two broad
categories; those which result in prompt deaths and those which result
in delayed deaths.
Prompt deaths are perhaps best exemplified by those that
result from accidents, for'example; automobile collisions, falls and
electrocutions. The causes of accidental deaths are generally easy to
identify, and the corresponding annual mortality rates for the U.S.
population are readily available for certain types of accidents.5,6
Since such deaths may be assumed to occur in the same calendar year as
the incidents initiating death, these rates can appropriately be used to
assess accident risk effects using CAIRD.
In CAIRD accident analyses, the cohort is assumed to be composed
entirely of members of a given occupational workforce. The accidental
death rate for that occupation is then used to represent the risk of on
the job fatalities. it should be noted, however, that the life table's
reference mortality data, which represent the summation of risks from
all causes of death, already contain the contribution from all
occupational accidental deaths. Since the accidental death rate is
added to reference mortality data in the cohort analysis, the risk of
death from that occupation is, in a sense, double counted. Ideally, the
accidental death contribution from all occupations should be subtracted
from the reference data before the accident rate is added. This proves
unnecessary, however, since the contribution of accidental deaths from
the occupational workforce to the overall mortality rate of the U. S.
population is exceedingly small (<1X of annual U.S. deaths due to
occupational accidents). The impact of double counting, therefore, is
negligible
In order to simulate employment under certain working
conditions, accident risk cases require exposing the cohort over a range
of ages. Consider a case in which a cohort of the total population is
exposed to an industrial, annual accident risk of 50. x10~6 between the
agps of 20 ard 30. Figure 2 shows the distribution of this risk across
the ages of the cohort. This exposure situation exhibits a
16
-------
100
oc
< 75
tu
35
z
<
UJ
O
(O
o
- 50
X
UJ
ACCIDENT RISK
EXPOSURE
INTERVAL
10
15
20
25
AGE
30
40
110
Figure 2
Age specific mortality rate distribution resulting from exposure to the
cohort to an annual accident risk = 50. x 10 between the ages 20 and 30,
17
-------
characteristic feature of the prompt death category; there is no
accumulation of risk due to exposure in preceding ages. An area
representing the annual risk rate has been entered for each age in the
exposure interval. Since the cohort faces the risk of death only during
the ages of exposure, all the resulting deaths occur in exposure
interval.
The CAIRO code requires the age distribution of increased risk
described above in order to generate a life table which corresponds to
the exposure situation. For accident risk cases, the ACCRSK subroutine
provides the risk distribution to the life table generating section of
the code. The subroutine uses an array with the same number of elements
as there are ages in the life table. The accident mortality rates are
added to the appropriate ages of the array, which is subsequently used
as the IXR column of the generated life table. The IXR data are added
to the reference mortality data as described previously. The remainder
of the life table is then generated, based on the sum of the incremental
and reference rates. CAIRD results for this example may be examined by
referring to problem 1 in the Sample Problems section.
The example above describes a case in which there is only one
exposure interval, i.e., age 20-30. The code has provision, however,
for accepting cases with multiple exposure intervals, each with a
different risK level if desired. The user can directly submit an
externally produced IXR array containing any mortality rate or
probability of death distribution. For further details, consult the
SWITCH case control parameter in the Glossary.
U . 2 Es2i§.i:i2D Ei§JS Analysis
Th«? code can also be used for risks of death which are delayed
until sometime after the period of exposure. The risk of cancer death
from low level radiation exposure falls into this category, and its
accurate assessment requires 'information on the relationship between
radiation dose and effects. The BEIR committee investigated various
aspects of population doses, including parameters concerning the delay
in death, models for estimating the risk of death and variations in
radioseneitivity with age. The results of these studies have been used
as the basis for the code's radiation risk algorithm. A short
description of the consideration given the BEIR parameters in the code
f ol 1 ow s .
a. Latent and plateau periods
The delay which is observed in radiation induced deaths can be
attributed to latent and plateau periods. In the code's context, th°
latent period is defined as the range of years following the exposure
period during which there is no risk of radiation induced cancer death.
The range of years following the latent period during which the risk of
induced cancer death persists is called the plateau period. The risk of
death is assumed to be uniformly distributed across the plateau period.
18
-------
The delay in radiation induced deaths has an important
consequence: the potential cancer victim experiences additional years of
life which would otherwise be forfeited had the same individual fallen
victim to an accident. Since the cancer may not appear for many years,
or be immediately detected once it has, the potential cancer victim may
not be aware of the pending illness. It is reasonable to assume that
the potential victim maintains a normal lifestyle during this period and
therefore is continually exposed to risks of death from normal daily
activities. The fact that the individual is committed to die from
cancer provides no immunity from other causes of death. Inevitably, a
portion of the individuals previously committed to die from cancer will
die from the competing causes of death.
Life tables are especially suited for calculating
radiation exposure effects because they contain the age specific
mortality rates from all causes of death. From the increased risk
perspective, the mortality rates represent the risk of death from all
competing causes, thus eliminating the need to account for every
competing risk of death individually. Life tables provide a framework
of the competing risks of death within which increased risks of death
may be analyzed. A second advantage is that the latent period and the
distribution of risk during the plateau period can be accurately
represented because the mortality rates in the life tables are age
specific.
b. Radiation risk models
The relationship between radiation dose and resulting
risk of cancer death is not completely understood. Results rom studies
show that for some types of cancer, an absolute risk model ib the best
predictor for the number of deaths resulting from radiation dose. This
modtl assumes that the normal cancer death rate is increased by an
absolute number of cases per unit dose per unit population. For other
cancer types, it appears that radiation dose results in a relative
increase in the number of cancer deaths naturally occuring in the
population: that is, a unit of radiation dose yields a percentage
increase in the population's normal incidence of cancer. Since
currently available data are insufficient to warrant the use of either
model under all exposure conditions or for all types of cancer, the
CAIRD code was designed to analyze radiation dose effects using either
absolute or relative risk estimates.
c. Exposure stages
The response to radiation dose appears to be dependent on
* -"= at which the dose is received. Consider radiation induced
1 *'. .nia deaths as an example. For a given radiation dose, children
have been found to suffer a higher incidence of leukemia than adults,
and in utero doses are estimated to result in a still higher rate.
Ci-?arly, a single leukemia risk estimate could not reflect the different
sensitivities observed at these life stages. Therefore, provision has
been made to include three risk estimates, one each for the following
life stage?: fetal, child and adult.
19
-------
d. Induced cancers
In addition to leukemia, radiation can induce cancer of
the lung, liver, bone, breast as well as other organs. The code will
accommodate up to nine types of cancer for each radiation dose. Each
type of cancer may have a different risk estimate for each of the three
exposure stages. Since latent and plateau periods may vary with the
stage of exposure, the code will accommodate different values for these
parameters for each cancer type as well. The code selects and use? the
appropriate risk estimates based on the ages specified for the exposure
interval.
U. 3 Rad.ia.tion Ei§k Distribution
a. Fetal stage dose
Analysis of fetal exposure cases is simplified by the
fact that there is only one age interval during which doses can be
received. Although the average gestation period might be more
accurately represented by the ages -0.75 to C, the code recognizes -1 to
0 as a fetal exposure case. It is assumed that there is no ill effect
from the radiation during gestation, since the cohort analysis requires
100,000 live births. Unlike the annual dose input requried for child or
adult stage exposures, the dose input for fetal exposure cases is the
total dose received by each member of the cohort during the 9 month
gestation period.
1) Absolute risk model
'g
In the example illustrated Figure 3, it is assumed
that each member of the cohort receives a 1.0 rem whole body fetal dcse.
Table III shows the latent and plateau periods and the absolute model
risk data for in utero exposures as stated in the BEIR report.
The BEIP committee used a form of life table
analysis in calculating the excess number of cancer deaths for certain
exposure conditions. The risk estimates they provide are based on the
number of cancer deaths observed in control and exposed populations.
Since competing risks exist is both populations, their effect is
canceled when the control data is subtracted from the exposed population
data. Risk estimates derived in this manner can be used in subsequent
competing risk analyses without double counting competing risk impacts.
For whole body exposure, the BEIR report estimates
of risk are provided for two cancer types; leukemia and all other cancer
types combined. The absolute risk estimate faced by the cohort is 25.0
deaths/106/rem/year for each cancer type. For in utero exposures, the
plateau period is taken to be 10 years, with no latent period assumed.
For the example in Figure 3, the reference probabilities of deaths for
the first ten age intervals of the life table should therefore be
increased by 50.x10~6 (25. x 10~6 for each cancer type) to reflect the
risk of death from the 1.0 rem in utero dose.
20
-------
50
E
I
LU
Q
O
x 25
LU
5
E
E
O
LEUKEMIA
10
15
20
110
AGE
50
E
I
LU
n
O
f»
x 25
LU
h-
E
>
E
o
ALL OTHER CANCER
10
15
20
^f '
; I 110
AGE
Figure 3
Age specific mortality rate distribution for leukemia and all other cancers
following a 1.0 rem fetal stage (in utero) does to the cohort. BEIR absolute
risk model data are used.
21
-------
TABLE III
BEIR Risk Model Data
Risk Estimate
Age of Ir-
" radiation
In
Utero
0-9
Years
10 +
Years
Type of
Cancer
Leukemia
All other
cancer
Leukemia
All other
cancer
Leukemia
All other
cancer
Duration
of Latent
Period
(years)
0
0
2
15 ^
2
15
Duration
of Plateau
Region
(years)*
10
10
25
(a) 30
(b) Life
25
(a) 30
(b) Life
Absolute
Risk
(deaths/10 /
yr/rem)
25
25
2.0
1.0
1.0
5.0
Relative
Risk
(% incr. in
deaths/rem)
50
50
5.0
2.0
2.0
0.2
* Plateau region = interval following latent period during which risk
remains elevated.
Source: The Effects on Populations of Exposure to Low Levels of
Ionizing Radiation, Table 3-2, p. 171
22
-------
The figure shows the risk distributions for the
example using the BEIP data. Since the latent period equals zero, the
risk plateau period begins at birth. Unlike the accident case, the risk
of death is not experienced in the exposure interval, nor is it confined
to a single age interval, but is distributed uniformly over the first
ten years of the cohort's life.
The code requires the numerical equivalent of the
risk distributions in Figure 3 to generate the modified life table
corresponding to the example. For fetal radiation exposure cases, these
distributions are produced by the FETRSK subroutine.
The subroutine begins with the risk array, IXR.
Using the latent and plateau data for the first cancer type, the risk
estimate is added to the appropriate elements of the array. In the
example, this would result in the 25.0X10~6 leukemia risk estimate being
added to the elements for each age between 1 and 10, with the rest of
the array retaining 0.0 values. The completed leukemia risk
distribution is returned to the main program as the FETAL array.
The individual cancer risk distributions are stored
in a three dimensional array called ALLCAN before being added to the
life table. As shown in Figure U, the ALLCAN array is designed to store
age specific risk distribution for all three exposure stages of each
cancer type. The ages, exposure stages and cancer types are represented
by the rows, columns and planes of the array, respectively. The purpose
in retaining the individual distributions is to enable calculation of
the number of incremental deaths either by cancer type or by stage of
exposure or by both.
As the data calculated by FETRSK are added to the
appropriate column of the ALLCAN array, they are multiplied by the
corresponding age and cancer entry of the CANMOR array. For absolute
risk cases, CANMOR is initialized with values of 1.0 and hence has no
effect on the data added to ALLCAN. Its purpose will be discussed in
the relative risk model example to follow.
To obtain the total risk from a given cancer type,
the risks for that cancer type from each stage of exposure must be
summed. Similarly, the total risk for a given stage can be obtained by
summing the contribution for that stage from each of the cancer types.
Finally, summing the three stage subtotals or the cancer type subtotals
will provide the total increased risk of death from all the stages of
all the cancers. These summations are also performed as the data are
read into the ALLCAN array.
In this example, the second and final cancer type is
all other (non-leukemia) cancers. As with leukemia, the -1 beginning
age of exposure calls the FETRSK subroutine, which generates the
distribution and returns it to be stored, this time in the fetal stage
of the all other cancer plane of ALLCAN. The data are added to the all
other cancer total risk column and the fetus stage total risk column.
Finally, the all other total risk is added to the all cancer column in
23
-------
ALLCAN ARRAY
AGES
I
A.O.
FETAL
LEU "*\^X^ A.O.
FETAL ^"\ CHILD
LEU ^v^X""^ A'°-
ADULT
LEU ^
ADULT
100
110
TOTCAN
TOTAL CANCER RISK
ARRAY FOR ALL STAGES
OF ALL CANCERS
Figure 4
ALLCAN storage array for radiation induced cancer mortality data. The total
cancer mortality array (TOTCAN) is the radiation risk input to the life table.
24
-------
•the third plane which already contains the leukemia total risk da4:;:.
This is the sum of all risks resulting from the radiation dose, and .s
used as the radiation risk input to the increased probability of ceat":
column, IXR. The remainder of the life table is then generated or the
basis of the combined radiation and reference mortality risks.
2) Relative risk model
Radiation exposure cases may also be analyzed us'ino
relative risk estimates. The procedure used differs slightly from thar
used for absolute risk. This may be demonstrated through
reconsideration of the previous example using relative risk estimates.
The EEIR absolute risk estimates are expressed as mortality rates, and
since this format is required for the life table, these estimates can be
used as initial input for the IXP. column of the table. Relative risk
estimates, however, are expressed as a percentage increase in the
natural cancer mortality rate. It is therefore necessary to first
supply the natural mortality rates to the code for the calculation cf
the number of deaths due to radiation exposure.
For relative risk cases, natural cancer mortality
rates are read into the CANMOR array. After these data have- been
entered, examination of the beginning age of the first exposure interval
causes FETFSK to te called. In a manner completely analogous to that
used for absolute risks, the distribution of the percent increases? in
cancer is calculated using the leukemia latent and plateau periods as
shown in Figure 5. The risk faced by the cohort in each age of the two
plateau periods is thus a 50% increase in the natural mortality rate of
the two cancer types.
FETRSK generates the leukemia risk distributicr. as
percentage increases in the natural cancer mortality, and returns it as
the FETAL array in the main program. As these increases in the natural
cancer mortality rate data are added to ALLCAN, they are multiplied by
the corresponding age and cancer entry of CANMOR. Since CANMOF. now
contains the natural cancer mortality rate data, the resulting product
is the mortality rate due to the radiation dose.
Figure 6 shows the natural mortality rates for both
leukemia and all other cancers for the first 20 age intervals.7 As the
distribution shown in Figure 5 is multiplied by natural mortality rates
in Figure 6, the mortality rate due to radiation is calculated (shaded
portion of bars in Figure 6). The resulting mortality rate
distributions are stored in the ALLCAN array in the same manner as the
absolute risk data. This procedure is performed for each cancer type
using its own natural mortality rate data. The sum of the leukemia and
all other cancer mortality rates again serves as the initial radiation
risk input to the IXR column.
25
-------
100 i-
LEUKEMIA
110
100
4 lu
<
2 <
— uj
85
< c
UJ UJ
50
ALL OTHER CANCER
10
AGE
15
20
110
Figure 5
Age specific percentage increase in normal caner mortality for leukemia and
all other cancer following a 1.0 rem fetal stage (in utero) dose to the
cohort. BEIR relative risk model data are used.
26
-------
75,-
CO
Z
LU
Q 50
ID
O
5 25
<
oc'
O
S '
LEUKEMIA MORTALITY
-PLATEAU PERIOD-
.RADIATION INDUCED
.NATURALLY OCCURING
10
15
20
110
AGE
ALL OTHER CANCER MORTALITY
NATURALLY OCCURING
AGE
Figure 6
Age specific radiaton induced mortality rates for leukemia and all other
cancer following a 1.0 rem fetal stage (in utero) dose to the cohort.
Naturally occurring 5-year cancer mortality rates shown for ages 0-20 were
calculated from NCHS data. Radiation induced mortalities (shaded bars)
during the plateau period are products of age specific % increase data
(Figure 5) and naturally occurring mortality rates.
27
-------
b. Child and adult stage exposures
1) Absolute risk model
The cohort's 110 age intervals are divided into
child and adult life stages by a user selected age. Exposure intervals
that include the separation age are permitted: the code uses the
appropriate latent, plateau, and risk data for the child and adult
segments of the exposure interval. Child or adult risk distributions
are calculated in nearly the same manner as those for fetal stage doses.
The distributions may be more complex, however, since it is possible to
expose the population over consecutive age intervals.
Figure 7 shows the leukemia and all other cancer
absolute risk distributions following a 1.0 rem dose to the cohort for
an adult stage exposure between the ages 20 and 30. Child or adult
stage doses are assumed to be accumulated at a constant rate over each
age in the exposure interval. The cohort does not accumulate the full
annual dose, therefore, until the end of each exposure age. Since a
year is required to receive the full dose, a year is also required for
the cohort to reach the full risk level during the plateau period. The
assumption of chronic dctee accounts for the one year extension of the
plateau periods shown in Figure 7, as well as the gradual risk increase
during the first, and decrease in the last, plateau ages.
The individual cancer risk distributions for each
exposure age interval are pictured as parallelograms. The total risk
for multiple annual exposure intervals is shown as a stacked set of the
individual distributions, each offset a year by the succeeding ages of
exposure. Differences in the cancer risk produces risk distributions of
different slope and size.
The CARSK subroutine generates the numerically
equivalent cancer risk distributions for rhild and/or adult exposure
cases. Once the exposure stage for a given case is determined, the code
selects the appropriate latent, plateau aT->d risk estimate data, and
produces the risk distributions for each cancer type. The distribution
data are stored in the ALLCAN array, and added to the life table
mortality rates. The total radiation risk used as initial input to the
IXR column is shown outlined in Figure 7.
2) Relative risk model
As with fetal stage exposures, relative risk cases
require input of the natural cancer incidence rates for the cancer types
under study. The CARSK subroutine generates the relative risk cancer
distributions in the same manner as that used for absolute risk. Using
the percentage increases as in the fetal exposure example, the
distribution data are multiplied by the appropriate CANMOR entry as they
are stored in the ALLCAN array. The resulting cancer mortality rates
are subsequently added to the IXR column of the life table, translated
to probabilities of death, and then used to generate the remainder of
the table.
28
-------
7.0
6.0
K)
ID
£ 5.0
Ul
,f4.0
o
<
oc
>
oc
O
3.0
2.0
1.0
TOTAL CANCER RISK:
LIFETIME PLATEAU
ALL OTHER CANCER
(30 YEAR PLATEAU)
10 YEAR
EXPOSURE
INTERVAL
20
30
40
50
60
AGE
Figure 7
70
80
90
100
110
Age specific mortality rate distribution for leukemia and all other cancer following a 1.0 rem annual dose to cohort from age
20 to 30. BEIR absolute risk model data are used. Small parallelograms represent risk of death from leukemia - the larger
one, risk of death from all other cancer assuming 30 year plateau period. If lifetime plateau assumed, area inside dashed
lines included in all other cancer risk. Heavy solid line shows total cancer risk for 30 year plateau; heavy dashed line
shows added total risk for lifetime plateau.
-------
U.U Combined Accident and Radiation Risk Analysis
It is possible to use the code for cases involving both
accident and radiation risk. These may have different exposure
intervals for each type of risk and may use either radiation risk model.
The incremental mortality rates for the accident and radiation risk are
determined by combining the methods described previously.
30
-------
5. CAIRO SUMMARY TABLES
The code generates a summary table for each case analyzed. This
table includes all input data and results from comparisons between the
generated life tables and the corresponding reference life tables. The
following features may be examined in the summary tables shown for
sample problem 3.
5. 1 Normalization of Output Data
Any age may be selected as the beginning of an exposure
interval. Since each age begins with a different number of survivors,
however, direct comparison of cases beginning at different ages might be
misleading. To facilitate case comparisons, output data are normalized
to 100,000 survivors at a user selected age, such as the beginning age
of exposure. The generated life table, if requested, will be printed
from the selected age through age 110.
5 . 2 Calculation of Output Data
The code uses U parameters for comparison between generated
and reference life tables. The methods used in these comparisons are
dicussed below: 'j
1) Sum of premature deaths
uo^ x 100,000
< ADDEAD = I IXRLXR(i) 1 * ..._,
1=1 x (•!•->)
where x = age selected for normalization
2) Years of life lost .
The code calculates the years of life lost due to
premature deaths. The comparison is made by subtracting the total years
of life left to the cohort in the generated life table from the years
left to reference cohort at the -age selected for normalization:
YLL = (t * - TXR(x)) x 100,000 (16)
V
3) Average years of life lost
The average years of life lost per premature death is:
AVGYLL = YLL (17)
ADDEAD
U) Decrease in life expectancy
If the years of life lost is divided by the initial
cohort size, the quotient is the decrease in cohort's life expectancy:
DLE = YLL (18)
100,000
31
-------
5.3 Premature Dejath Breakdowns
The generated life tables list the number of deaths for each
age due to all incremental risks in the IXRLXR column. The normalized
sum of this column is the first entry in the output data section of the
summary table. For cases including radiation exposure, a breakdown of
deaths by cancer type and stage of exposure is also provided.
The subtotals for radiation and accident risk are produced by
using the accident risk array to subtract the number of accidental
deaths from the total number of deaths in IXRLXR column. The remaining
deaths in IXRLXR are due to radiation and are further categorized by
using the cancer and stage risk distributions stored in the ALLCA.N
array. The subtotals for these categories are shown in the summary
table. Tables of the age distribution of radiation death by cancer type
or stage of exposure may be obtained through use of output options.
Although the results in the output data section of summary table
are normalized to 100,000 at a user selected age, the radiation death
subtotals and distribution tables are normalized at age zero. The us°r
selected age is not used for the latter data because the zero age
results provide a baseline for determining normalization effects and
there is little need to compare the subtotals or death distribution
tables between cases. '*
32
-------
6. REFERENCES
1. Benefit/Risk Patio of Mammography, R.P. Chiacchierini, F.E. Lundin,
.from Breast Carcinomo; The Radiologist Expanded Ro3,ex Edited by
Wende Westinghouse Logan, M.D., John Wiley 6 Sons, Inc., Copyright
1977.
2. U.S. Decennial Life Tables for 1969-71, Vol. 1, No. 1, DHEW
Publication No. (HRA) 75-1150, U.S. Department of Health,
Education, and welfare, Public Health service. Health Resources
Administration, National Center for Health Statistics, Rockville,
Maryland (May 1975).
3. The Effects on Population of Exposures to Low Levels of Ionizing
. Radiation, Report of the Committee on the Biological Effects of
Ionizing Radiations, National Academy of Sciences - National
Research Council, Washington, D.C. (1972).
4. Bunger, Byron M., John R. Cook, Mary K. Barrick, Life Table
Methodology for Evaluating Radiation Risk, Office of Radiation
Programs, U.S. Environmental Protection Agency (in preparation).
5. Accident Facts, 1976 Edition, National Safety Council, Chicago,
Illionis (1976).
6. Statistical Abstract of the United States, 1975, U.S. Department of
Commerce, Bureau of the Census, 1975.
7. Vital Statistics of the United States, 1969, Volume II, Mortality,
U.S. Department of Health, Education, and Welfare, National Center
for Health Statistics.
33
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APPENDIX A
Input Requirements
User Aids
'j
Glossary
35
-------
INPUT REQUIREMENTS
Table I shows the data and sequence requirements for the CAIRO
code. The quantity of input data required varies among cases, depending
on the type of risk data available and the analysis desired. Special
consideration is given to multiple case runs, as is explained in the
USER AIDS section. The sample problems section illustrates typical
input data and resulting output. A brief discussion of input data
format follows. consult the Glossary for additional details on input
variables.
1) Title card - The first card is reserved for an alpha-numeric
title or description of the case (or cases) that follow. The entire 80
column field is printed as the top centered line of the summary table
(see sample problem output) .
2) Parameter Control and Case Variables card - The data on this
card set up the configuration the code uses in analyzing any risk data.
By specifying the seven columns of the SWITCH array, the user can choose
among many combinations of population, risk type and model, output, etc.
The remaining data specify values for case variables. These include:
the number of cancer types resulting from the radiation exposure
(NOCAN), the age to be used in separating child and adult doses
(SEPAGE), the age at which output data are to be normalized (NORMAG) ,
and the beginning ages for up to 9 exposure intervals (BEGAGE).
3) The ending ages of the exposure intervals (ENDAGE) are coded
to form sequential pairs with the beginning age data. The doses used
for the exposure intervals (DOSE) are coded in order corresponding to
the exposure intervals. The doses used only for radiation risk cases,
and their units must match those of the cancer risk estimates used.
In our society, the 20th year of life is lived when one is
referred to as being age 19. In the code, age 19 refers to the 19th
birthday, not the 20th year of life. Hence the age interval 20-30
represents the time between the cohort's 20th and 30th birthdays.
The code is written so that adjacent exposure intervals are
identical to single age intervals which encompass the same ages. One
rem during the 20-25 and 25-30 age intervals, for example, is equivalent
to the same dose of 1.0 rem during the 20-30 age interval. The only
restriction on consecutive year exposure intervals is that they may not
begin with the fetal stage. Hence, the exposure interval -1 to 10 is
not permitted, but may be replaced by the two equivalent intervals, -1
to 0 and 0 to 10.
it) The remaining 6 doses are coded on this card. All unused case
variable data should be coded 0.0.
5) Reference Life Table Data Cards - The largest source of input
data is the reference life table data required for calculation of output
statistics. The age specific values for 3 of the reference table
columns, the probability of death, the number of survivors, and the
37
-------
number of years of life remaining, are input to CMRD. The reference
data are required for the male, female and total populations. Since
these data do not change, the merits of storing the data on disk should
be considered. Should data for a different population become available,
they can be read from cards. The reference data used for the sample
problems may be found in Appendix B.
6) cancer Variables Card - Used only for cases where one of the
risks being analyzed results in death by cancer induction (e.g.,
radiation exposure). The first two variables, CASREP and CANREP, are
used for controlling input in multiple case runs (see User Aids and
Glossary) .
CANNO is a numerical identifier for each cancer type, and
CANCER (3,N) is used for alpha numeric description of the cancer types.
This card also contains the fetal, child and adult stage
latency, plateau, and risk estimate data for each cancer type. If the
case being analyzed involves only a single stage of exposure, the other
stage data should be coded as zeros.
7) Cancer Mortality Cards - used in relative risk analyses.
These cards are required for each cancer type analyzed. They are read
once for the first relative risk case and retained for use in similar
cases (see CANREP). Cancer mortality data are only available in
abridged format. That is the mortality data are reported for five year
intervals whereas the life table data are reported for each year. CAIRO
assigns the five year values to each year in the interval, thus
generating a format compatible with the life table. The last abridged
mortality value is for ages 85+ and is used for ages 85-110 in the
expanded format.
8) Single Non-radiation Risk Card - Used for exposure intervals
involving the same accident risk rate. The single value (SINRSK) is
assigned to each age in the exposure interval.
9) Multiple Non-Radiation Risk Cards - used for cases involving
age-dependent accident risk rates, e.g., to model several changes in
occupations throughout the cohort's lifetime. ADDRSK must be provided
with 110 entries.
38
-------
TABLE I
CAIRO Input Data Sequence and Format
Card Sequence Columns Data
CASE VARIABLES - Required for all cases:
1.
2.
3.
a.
5.
1
1
1
1
Card
Card
Card
Card
330 Cards
1-80
1-7
10-15
16-20
21-25
26-70
1-U5
46-76
1-60
1-30
TITLE
SWITCH (7)
NO CAN
SEP AGE
NORMAG
BEGAGE(9)
ENDAGE(9)
DOSE(1-3)
DOSE(U-9)
REFTBL(111 ,3,3)
CANCER VARIABLES - Required for radiation risk cases only:
6.
N Cards*
Format
20A«
711
15
15
15
915
915
3F10.9
6F10.9
3F10.9
1
2
3-5
10-22
26-30
31-35
36-UO
U1-U5
tt 6- 50
51-55
56-60
61-65
66-70
CASREP
CANREP
CANNO
CANCER (3, N)
FLTNCY
FPLATO
FDEATH
CLTNCY
CPLATO
C DEATH
ALATNCY
APLATO
ADEATH
11
11
13
3AU
15
15
F5.0
15
15
F5.0
15
15
F5.0
CANCER MORTALITY - Required for each cancer type for relative risk cases only:
7. 3 Cards 1-80 MORTAL(22) 8F10.9
ACCIDENT MORTALITY - Required for single accident risk cases only:
8. 1 Card 1-10 SINRSK F10.0
ADDITIONAL MORTALITY - Required for multiple accident risk cases only:
9. 1*» Cards 1-80 ADDRSK(110) 8F10.0
*N = Number of cancer types
39
-------
USER AIDS FOR DATA INPUT
A series of exposure cases which differ only by the cancer variable
data may be analyzed without repetitious input of identical case
variable data by the use of the CASPEP variable. CASREP is input with
the cancer variables for radiation risk cases and with accident
variables for accident risk cases. It is used to determine the step to
be executed after the current case is completed.
When CASREP is set equal to 1, execution resumes at the beginning
of the code and a complete set of input data are required for the next
case. When not set equal to 1, the current case variables are retained,
and execution continues with the next cancer variables coded. Thus one
s
-------
GLOSSARY
Term Definition
ACCRSK Subroutine that calculates accidental
risk arrays
ADDEAD Sum of deaths due to incremental risk(s) of death
ADDRSK(AGE) Array for age specific non-radiation risk distributions
ADEATH(CAN) Array for adult stage exposure radiation risk estimates
ADEXP (J) Array for adult exposure intervals
ADULT(AGE) Array for adult stage exposure radiation risk
distributions
AGE Index for cohort's age
ALLCAN (AGE, STG, CAN) Storage^ array for radiation risk distributions by
individual cancer type and stage of exposure.
ALTNCY(CAN) Array for adult stage exposure latent periods
APLATO(CAN) Array for adult stage exposure plateau periods
ARCO (AGE) Array for age specific accident risks expressed as
probabilities of death. These risks are converted to
mortality rates before being added to the reference table
data
AVGYLL Average years of life lost per premature death
BEGCAN The first cancer type for which the portion of total
deaths is to be calculated
BEGSTG The first stage of exposure for which the portion of
total deaths is to be calculated
BEGAGE(J) Array for the beginning age of exposure intervals
CAN Index for cancer type
CANCER (3,CAN) Array for alphanumeric description of cancer types
CANMOR(AGE,CAN) Array for age specific natural cancer mortality
rates
CANNO Identification number for each cancer type
CANREP Input control variable for cancer mortality data
-------
CARSK
CASREP
CDEATH (CAN)
CHILD (AGE)
CLTNCY(CAN)
CPLATO(CAN)
OLE
DOSE (J)
ENDAGE(J)
FETAL (AGE)
FETRSK
FDEATH (CAN)
FLTNCY (CAN)
FPLATO(CAN)
GLTABL(AGE,N)
I
INCMOR
Subroutine that calculates radiation risk distributions
for child and adult stage exposures
Input control variable for case variables data
Array for child stage exposure, radiation risk estimates
Age specific radiation risk distribution for child stage
exposure
Array for child stage exposure latent periods
Array for child stage exposure plateau periods
Decrease in life expectancy for entire cohort resulting
from increased risks of death
Array for annual radiation dose rates (or total dose for
fetal stage exposures)
Array for the ending age of exposure intervals
Array for ^etal stage exposure radiation risk
distributions
Subroutine that calculates fetal exposure radiation risk
distributions
Array for fetal stage exposure radiation risk estimates
Array for fetal stage exposure latent periods
Array for fetal stage exposure plateau periods
Array for generated life table
Index for SWITCH parameters
Incremental risks of death expressed as mortality rates
INTAGE(AGE,2) Age interval array
INTBLK
J
K
KIDEXP(J)
L
Indicator for initially addressed 5-age block of
generated life table
Index for exposure interval sets
Index for alphanumeric description of cancer type
Array for duration of child stage exposure
Index for abridged cancer mortality data
-------
LINE Index for line of life table.
LSWl Literal translations for SWITCH (1) user options
LSW2 Literal translations for SWITCH(2) user options
LSW3 Literal translations for SWITCH(3) user options
LSWU Literal translations for SWITCH(U) user options
LSW5 Literal translations for SWITCH(5) user options
LSW6 Literal translations for SWITCH(6) user options
LSW7 Literal translations for SWITCH(7) user options
M Index for radiation doses
MOPTAL (AGE, CAN) Array for age specific natural mortality rate for
cancels in abridged format
NOARCO(AGE) Array for age specific accident risks expressed as
mortality rates. These risks do not require conversion
before being added to reference table data
NOCAN The number of cancer types resulting from the radiation
dose specified
NOPMAG Age at which output data are normalized
NOWBLK . Indicator for current 5-age block of the generated life
table
POP Index for population
REFMOR Reference risk of death from all causes expressed as
mortality rates
REFTBLfAGE,PEF,POP) Storage array for male, female and total population
reference life table data
SEPAGE user selected age that separates child and adult life
stages
SINRSK Variable for single accident risk value
STATRF User selected statistical reference year, used for
normalization of results
STRTAG Beginning age of adult stage exposure
SWITCH SWITCH array data are used to specify the user options on
seven case control parameters:
-------
a) Population
SWITCH (1)
b) Input Source
SWITCH (2)
c) Risk Model
SWITCH (3)
0 End "of run
1 Use male referene life table data
2 Use female reference life table data
3 Use general reference life table data
1 Input reference life table data
2 Input reference life table data from cards
1 No radiation risk
2 Absolute radiation risk model case
3 Relative radiation risk model case
d) Additional Risk
SWITCH
1 No additional risk
= 2 Single value accident risk - no risk
conversion required
= 3 Multiple value accident risk - no risk
coversion required
= U Single value additional risk - conversion to
mortality rate required
= 5 Multiple values additional risk - conversion to
mortality rates required
e) Stage & Cancer Analysis
SWITCH (5) =
f) Output
SWITCH
1 No proportional analysis
= 2 Provide portion of total deaths by
stages in summary table
= 3 Provide portion of total deaths
by cancers in summary table
= U Provide portion of total deaths by stages
and cancers in summary table
(6) = 1 Summary table only
= 2 Summary table and generated life table
= 3 Summary table, generated life table
and stage table
= U Summary table, generated life table
and cancer table
= 5 Summary table, generated life table, stage
table and cancer table
g) Dose Rates
SWITCH (7) = n n = number of dose rates (0-9)
TDEAD
Temporary storage array for the premature number of
deaths
TITLE (20)
Array for alphanumeric description of cases
-------
TOTCAN Summary plane of the ALLIXR array for sum of all cancer
types used
YLL Years of life lost
45
-------
APPENDIX B
Sample Problems
Reference Life Table Data
Cancer Mortality Data
Code Listing
-------
SAMPLE PROBLEMS
The first four sample problems correspond to the examples discussed
in preceding sections. The remaining two problems exhibit additional
input and output features of the code. In each case, the output is
preceded by a listing of the input statements used in the problem.
The reference life table data are also required for these or any
other problems. Due to the quantity of reference table data, however,
it has proved convenient to have these data read directly from disk,
thus eliminating the need to submit these data along with the other
problem input. A listing of the reference table data used in the sample
problems is provided in Table I.
49
-------
Sample Problem 1.
This problem deals with exposure of the total population to 'an
accident risk of 5. 0 x 10-s for ages 20 to 30. The 0.0005 entry for the
first DOSE is not used in any calculations, but to document the risk
rate in the summary table. Note that the "*** END OF RON ***" statement
is actually the title input for the final (dummy) case in each run.
n*** OUTPUT DATA ***" are normalized to 100,000 survivors at
age 20 as requested (NORMAG = 20) , whereas the "NUMBER OF DEATHS CAUSED
BY NON-RADIATION RISKS" are normalized at age zero. The generated life
table is provided for this problem (SWITCH (6) =2)).
Input Data:
• • • • I • »*•!• •••*!••••*.••• «~T« •••.J* •••"?*• •••^••••'^•••••^••••+, •••()• • • • ~t~* •••/« •••*!•• *a«O
Of TOT\L rjT'l'UTI.);.' TO ACCIDCIT •IIS!' = 3.0005 T"T';'L;::N AC'IS ::', - 3:
3112121 0 0 20 20 0 0 0 0 0 0 0 0
30 0 0 0 000 0 0 0.0005 0.0 j.O
0.0 0.0 0.0 0.0 C.O u.O
1 0.0005 >j
*** EN:: or nu.i ***
51
-------
EXPOSURE OF TOTAL POPULATION TO ACCIDENT RISK • 0.0005 BETWEEN ACES 20 - 30
NUMBER OF DOSE RATES! OKE
RADIATION RISK MODEL! NCNF
ADDITIONAL RISK! ACCIDENT (SINGLE)
POPULATION AT RISK! GENERAL
REFERENCE TABLE INPUT SOURCE I DISK
ADDITIONAL ANALYSIS! NQNE
ADDITIONAL OUTPUT! LIFE TABLE
»«* IHPUT DATA ««*
DOSE
0.000500000
CHILD AGE INTERVAL •
ADULT ACE INTERVAL •
OUTPUT DATA BASED OK AGE
INTERVAL
ACE INTERVAL
20 - 30
0 - 0
0-110
• 20-110
*** OUTPUT DATA »»*
NUMBER OF PREMATURE DEATHS «
DECREASE IN PCPULATION LIFE EXPECTANCY «
TOTAL YEARS OF LIFE LOST 10 PREMATURE DEATHS •
AVERAGE YEARS OF LIFE LoST PER PREMATURE DEATH
495.10376
0.23953
23952.7891
40.37932
NUMBER OF DEATHS CAUSED BY NON-RADIATION RISKS
479.3162*
TOTAL NUMBER OF INCREMENTAL DEATHS
495.10376
-------
GENERATED LIFE TABLE FOR THE GENERAL POPULATION! UNITED STATES. 1969-71
X TO X«T
YEARS
20- 21
21- 22
22- 23
23- 24
2«i- 25
25- 26
26- 27
27- 28
28- 29
29- 30
30- 31
31- 32
32- 33
33- 34
34- 35
35- 36
36- 37
37- 38
38- 39
39- 40
40- 41
41- 42
42- 43
43- 44
44- 45
45- 46
46- 47
47- 48
48- 49
49- 50
50- 51
51- 52
52- 53
53- 54
54- 55
55- 56
56-57
57- 58
58- 59
59- 60
TQX
0.0014058276
0.0014699168
0.0015135479
0.0015262257
0.0015077623
0.0014683832
0.0014392544
0.0014099967
0.0014433654
0.0014768751
0.0015633690
0.0016268700
0.0017157350
0.0016346690
0.0019436760
0.0020H50530
0.0022465020
0.0024449100
0.0026640240
0.0028955160
0.0031503820
0.003396B270
0.0037104150
0.0040361950
0.0044350240
0.0048369310
0.0052883350
0.0057355890
0.0062457010
0.0067761420
0.0073843460
0.0060394040
0.0087552080
0.0095695430
0.01042S3840
0.01 13735' 70
0.01234R1 730
0.0134170850
0.01'. 5143190
0.015705B340
IXR
0.0004995237
0.0004995076
0.0004994967
0.0004994936
0.0004994982
0.00049950BO
0.0004995153
0.0004995226
0.0004995143
0.0004995059
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
o.o
0.0
o.c
0.0
0.0
0.0
TQXR
0.0019053515
0.0019694244
0.0020130446
0.0020257193
0.0020072605
0.0019678912
0.0019387698
0.0019095194
0.0019428797
0.0019763810
0.0015633690
0.00162B87CO
0.0017157350
0.0018346690
0.0019436760
0.0020850530
0.0022485020
0.0024449100
0.0026640240
0.0028955160
0.0031503820
0.0033968270
0.0037104150
0.0040381950
0.0044350240
0.0048369310
0.0052883350
0.0057355890
0.0062457010
0.0067761420
0.0073843460
0.0080394040
0.0087552080
0.0095695430
0.0104293840
C. 01137351 70
0.0123481 730 .
0.0134170B50
0.0145143190
0.0157058340
LXR
96716.0001
96531.7221
96341.6101
96147.6702
95952.9020
95760.2995
95571.8537
95386.5619
95204.4194
9^019.4486
94831.6540
94683.3971
94529.1702
94366.9832
94193.8510
94010.7687
93814.7512
93603.8086
93374.9557
93126.2026
92856.5542
92564.0206
92249.5966
91907.3123
91536.1726
91130.2075
90689.4170
90209.8210
89692.4145
89132.2225
88528.2499
87874.5267
87168.0679
86404.8933
85578.0380
84685.51 18
83722.3396
B268B.5217
81579. OB28
B039b.01bO
DXR
164.2780
190.1119
193.9400
194.7682
192 .6025
188.4459
185.2916
182.1425
1 84 .970 7 J
187.7946
148.2569
154.2269
162.1670
173.1322
183.0823
196 .0174
210.9427
226.8529
248.7531
269.6464
292.5336
314.4240
342.2843
371 .1396
405.9651
440.7905
479.5960
517.4065
560.1920
603.9726
653.7232
706.4588
763.1746
B26.8553
892 .5262
963.1721
1033.8179
1 109 .4389
1 184 .0648
1262.6708
TLXR
96623.6611
96436.6661
96244.6402
96050.2861
95856.6006
95666.0766
95479.2076
95295.4906
95111.9340
94925.5513
94757.5256
94606.2837
94446.0767
94280.4171
94102.3098
93912.7600
93709.2799
93489.3621
93250.5791
92991.3764
92710.2874
92406.8086
92078.4544
91721.7425
91333.1901
90909.6123
90449.6190
89951 .1176
69412.3185
68830.2362
88201.3683
67521.2973
66786.4806
65991 .4656
85131.7749
84203.9257
83205.4307
82133.8022
80987.0504
79763.6825
IXR
5102527.3169
5005903.4558
4909466.7897
4813222.1495
4717171.6634
4621315.2627
4525649.1861
4430169.9783
4334674.4877
4239762.5537
4144837.0024
4050079.4768
3955473.1931
3861025.1165
3766744.6994
3672642.3695
3576729.6296
3485020.3496
3391530.9675
3298260.3864
3205289.0100
3112576.7226
3020171.9141
2928093.4596
2836371.7172
2745036.5271
2654128.7148
2563679.0958
2473727.9781
2384315.6595
2295465.4233
2207284.0350
2119762.7377
2032976.2571
1946964.7915
IC6I853.0166
1777649.0909
1694443.6602
1612309.8580
1531322.8076
EXR
52.7578*1
51.857600
50.956945
50.060726
49.161326
48.259198
47.353366
46.444363
45.532282
44.619945
43.707315
42.774970
41.643943
40.915000
39.989284
39.066166
38.146769
37.231606
36.321634
35.417319
34.516716
33.626227
32.739134
31.859200
30.966348
30.122158
29.266135
26.419069
27.580125
26.750322
25.929412
25.116568
24.318111
23.526465
22.750987
21.985496
21.232673
20.491685
19.763765
19.047484
•»•»•
1
4
4
4
4
4
4
4
4
4
4
(
(
(
<
IWLMt
48.31191
48.21831
48.12231
48.02511
47.92831
I
47.63301
47.73961
47.64771
47.55601
47.46281
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
-------
GENERATED LIFE TABLE FOR THE GENERAL POPULATION! UNITED STATES. 1969-71
X TO X«T
YEARS
60- 61
61- 62
62- 63
63- 64
64- 65
65- 66
66- 67
67- 68
68- 69
69- 70
70- 71
71- 72
72- 73
73- 74
74- 75
75- 76
76- 77
77- 78
78- 79
79- 80
00- 81
81- 82
82- 83
83- 84
64- 85
85- 86
86- 87
87- 88
88- 89
89- 90
90- 91
91- 92
92- 93
93- 94
94- 95
95- 96
96- 97
97- 98
9B- 99
99-100
TOX
0.0169497920
0.0182S08890
0.0197391560
0.0213328730
0.0230609390
0.0249398750
0.0269892640
0.0291885240
0.0315150780
0.0340055480
0.0366062210
0.0394373270
0.0426603900
0.0464370910
0.0507610340
0.0555074940
0.0606015420
0.0659622230
0.0715430180
0.0773957380
0.0839450190
0.0912044050
0.0989276600
0.1069553060
0.1154920040
0.125597H570
0.1374576090
0.1497875580
0.1616319830
0.1728647690
0.1850059160
0.1988913820
0.2136738060
0.2285774150
0.2433460080
0.2577171570
0.2693423600
0.2806088680
0.2897884080
0.2979274610
IXR
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
o.o
0.0
c.c
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
TOXR
0.0169497920
0.0182908890
0.0197391560
0.0213326730
0.0230609390
0.0249398750
0.0269892640
0.0291885240
0.0315150780
0.0340055460
0.0366062210
0.0394373270
0.0426603900
0.0464370910
0.0507610340
0.0555074940
0.0606015420
0.0659622230
0.0715430180
0.0773957380
0.0839450190
0.0912044050
0.0989276600
0.1069553060
0.1154920040
0.1255978570
C. 1374576090
0.1497875580
0.1616319630
0.1728647690
0.1850059160
0.1968913820
0.2136738060
0.2285774150
0.2433460080
0.2577171570
0.2693423600
0.2806088680
0.2897884080
0.2979274610
LXR
79132.3471
77791.0703
76366.2025
74660.7586
73263.7636
71574.2324
69789.1800
67905.6214
65923.5565
63845.9705
61674.8533
59417.1700
57073.9156
54639.1201
52101.6383
49457.0951
46711.8557
43861.0452
40986.5539
36054.2522
35109.0152
32161.7883
29228.4915
26336.9853
23520.1049
20603.7209
18190.8161
15690.3518
13340.1323
11183.9402
9250.6310
7539.2095
6,039.7257
4749.1946
3663.6359
2772.1046
2057.6658
1503.4639
1081.5786
768.1496
DXR
1341.2768
1422.8678
1507.4439
1596.9951
1669.5312
1765.0524
1663.5566
1982.0649
2077.5860
2171.1172
2257.6833
2343.2544
2434 .7955
2537.2618
2644.7432
2745.2394
2630.8105
2894.4913
2932.3016
2945.2369
2947.2270
2933.2968
2891.5063
2816.6803
2716.3841
2612.9026
2500.4664
2350.2195
2156.1920
1933.3092
1711 .4215
1499.4638
1290.5312
1085 .5586
891 .5312
714.4190
554.2219
421 .6853
313.4289
228.8529
TLXR
78461 .7067
77079.6364
75614.4806
74062.2611
72416.9980
70661.7062
66847.4007
66914.5869
64664.7635
62760.4119
60546.0116
58245.5428
55856.5179
53370.4792
50779.4667
48084.4754
45296.4505
42433.7996
39520.4031
36581.6337
33635.4018
30695.1399
27762.7364
24928.5451
22161.9129
19497.2695
16940.5649
14515.2420
12262.0363
10217.2656
6394.9203
6789.4676
5394.4601
4206.4152
3217.8703
2414.8953
1780.5748
1292.5212
924.8641
653.7232
TXR
1451559.1251
1373097.4163
1296017.7799
1220403.2994
1146341.0383
1073922.0403
1003240.3341
934392.9334
867478.3445
802593.5810
739833.1691
679287.1575
621041.6147
565185.0968
511814.6176
461035.1509
412950.6755
367654.2250
325220.4254
285700.0223
249118.3886
215482.9869
184767.8470
157005.1086
132076.5635
109914.6506
90417.3811
73476.7961
58961.5541
46699.5178
36482.2322
26087.3119
21297.8443
15903.3842
11696.9689
8479.0986
6064.2033
4283.6285
2991 .1073
2066.2432
EXR
18.349436
17.651093
16.970647
16.302310
15.646767
15.004311
14.375299
13.760171
13.158852
12.570779
11.995702
11.432506
10.881356
10.343964
9.823350
9.321921
8.840383
8.378429
7.934808
7.507703
7.095568
6.699969
6.322182
5.961393
5.615475
5.283413
4.970496
4.682929
4.419863
4.175587
3.943756
3.725498
3.526293
3.348649
3.192721
3.058722
2.947099
2.849173
2.765502
2.689897
IXRLXR
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
-------
GENERATED LIFE TABLE FOR THE GENERAL POPULATIONi UNITED STATES. 1969-71
X TO X«T
YEARS
100-101
101-102
102-103
103-10*
104-105
105-106
106-107
107-108
108-109
109-110
TOX
0.3061180810
0.314(666670
0.3190661480
0.3314285710
0.3333333330
0.3333333330
0.3461538460
0.3529411760
0.3636363640
0.3571428570
IXR
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
TOXR
tf. 308 11 808 10
0.3146666670
C. 3190661480
0.3314285710
0.3333333330
0.3333333330
0.3461538460
0.3529411760
0.3636363640
0.3571428570
LXR
539.2968
373.1297
255.7182
174.1272
116.4165
77.6110
51.7406
33.8304
21.8903
13.9302
DXR
166.1671
117.4115
81.5910
57.7107
38.8055
25.8703
17.9102
11 .94.01
7.9601
4.9751
TLXR
456.2132
314.4239
214.9227
145.2718
97.0137
64.6758
42.7855
27.8603
17.9102
11.4426
TXR
1412.5200
956.3067
641.8828
426.9601
281.6883
184.6746
119.9988
77.2132
49.3529
31.4426
EXR
2.619189
2.562934
2.51C118
2.452001
2.419660
2.379490
2.319236
2.282360
2.254557
2.257161
.
IXRLXR
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
-------
Sample Problem 2.
This problem refers to the two cases discussed in section U.3A.
Both cases are analyzed here in one run. The input data are documented
in the summary table, whether they are used or not. It is advisable,
therefore, to code zeros for unessential variable input to avoid later
confusion as to what case was actually run.
The proper sequence, i.e., absolute risk cases before relative risk
cases, is shown. The CASREP is set equal to 1 on the all other cancer
card causes the next full case to be read. Note that since CANREP is
set equal to 1 on the relative risk leukemia and all other cancer cards,
subsequent input of that cancer •s natural mortality data (abridged
format) is required.
The summary table is expanded for cases which include radiation
risk in order to document latent, plateau and risk data, as well as
provide a breakdown of radiation .deaths by stage and cancer. The
radiation death breakdowns are always normalized at age zero.
Input Data:
« •• •!••»• I ••••>• • • • C!,
FETAL RV>i\Ti-n
3121421 2
0
12 i
12 2
FF:T\.L
3U1421
0
2 0
0 0 .1
0.0 i). 0
Li:ui;:vii\
ALL 07' :-C\L
0 -1
0 1
0.0
0
0
- -jj •*•. )~\i_
0 -1
0 0
0.0
0
OuD021347
000062375
PlPL'^ATIO:
0 0
:) 0
0.0
10 25.0
10 25.0
PJPl'LATlJ;
0 0
0 0
0.0
K' 0.5
000020230
000100071
: = i.o:i::i
0 0
0
0.0
0 0
0 0
I = i.OD.~-i
0 0
0
0.0
0 0
000016544
00014008'J
PC I
0
1.0
0.0
0.0
:jc.i
0
1.0
o.o
0000
0002
0.0
o
0
0
0.0
0
0
000032216
002TJ6321
U14124117
009740^4
10 0.5
000052229
003419071
014124127
0 0
000071818
004.^64605
014124127
i:JDivnu\:.: ".T-
000
0.0 0.0
0.0
0 n 0.0
00001034:; 000021?5'. 000023818
00022511H 0000488')', 000467433
0007403^4
0.0 0 0 0.0
000110358 000190325 0003.<(J229
006583333 003509036 010022733
014124127
56
-------
FETAL RADIATION DOSE 10 TOTAL POPULATION
PIJPULAT ION AT
NUMBER OF DOSE RAUSi ONE
RADIATION RISK MODEL: ABSOLUTE
ADDITIONAL RISK: sot
*** INPUT DATA ««»
DOSE AGE IMERVAL
l.CCCOOOOOO -1 - 0
CHILD ACE INTERVAL « 0-0
ADULT ACE INTERVAL • 0-110
CUIPUT DATA BASED OK ACE INTERVAL « 0-110
= l.OKEM >ER INDIVIDUAL'
ABSOLUTE RISK
RISK: GENERAL
REFlhENCE TABLE |M'UT SOURCE « DISK
ADDITIUNAL ANALYSIS: STAGES c CANCERS
ADDITIONAL OUTPUT' LIFE TABLE
««»
OUTPUT DATA ««*
NUMbtR UF PKLKATURE DEATHS • 46.68799
DICKLAiE IN PtPULATION LIFf FXPECTANCY « 0.03292
ILUL YlAkS OF LIFE LOST T'j PREMATUkE DEATHS • 3292«,C'>6e7
AVLMGI Y^ARS UF LIFE LOST PER PREMATURE DEATH • 67.33856
CANCER FlTAL CHILD
LATENCY PLATEAU DEATH KATL LAUNCY PLATEAU DEATH RATE
LEllKtMIA 0 10 25.000
ALL OTHER 0 10 25.000
CANCER FETAL
LEUKEMIA 24.44401
ALL OTHER 24.44401
TCTAL 4B.Hl'b03
TOTAL NUMBER OF INCREMENTAL DEATHS
0 C t.O
0 C C.O
CHILD ADULT
0.0 0.0
0.0 0.0
0.0 0.0
ADULT
LATENCY PLATEAU DEATH RATE
0 0 0.0
0 0 0.0
TOTAL
?<•. 44401
24.44401
4e.6b803
'i«.88799
-------
GENERATED Life TABLE FOR THE GENERAL POPULATION: UNITED STATES. 1969-71
X TO X«T
YEARS
0- 1
1- 2
2- 3
3- 4
4- 5
5- 6
6- 7
7- 8
8- 9
9- 10
10- 11
11- 12
12- 13
13- 14
14- 15
15- 16
16- 17
17- 18
18- 19
19- 20
20- 21
21- 22
22- 23
23- 24
24- 25
25- 26
26- 27
27- 28
2fl- 29
29- 30
30- 31
31- 32
32- 33
33- 34
34- 35
35- 36
36- 37
M- 3 0
3M- 39
J1)- 40
TOX
0.02C0195045
0.0012446919
0.0008582076
O.OOC6953356
0.0005730277
O.OOC5016875
0.0004712082
O.OOC4304362
0.0003793575
O.OOC34B7303
O.COC3078190
0.0002S7650C
O.OOC3490720
0.0004621690
0.0006267850
0.0008225290
0.0010064260
0.0011639520
0.00127B7460
0.00134^3370
0.0014061 790
O.C014702B40
0.001513926C
0.0015266070
O.C0150P.I39C
0.001461-7500
0.0014396140
0.0014103490
0.00 14437260
O.OOI477244C
0.0015633690
0.00162P6700
O.OOI7I5735C
0.001P346690
0.0019436760
0.0020850530
O.U022485020
0. C024449IOU
0.002M.40240
O.U02BV.-51 60
IXR
0.0000494982
0.0000499676
0.0000499773
O.OOC0499813
O.C0004S9U44
O.C000499662
0.0000499869
0.0000499680
0.0000499692
0.0000499900
C.O
C.O
0.0
O.C
O.C
0.0
c-c
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
C.O
0.0
0.0
c.c
0.0
0.0
0.0
0.0
O.C
0.0
0.0
O.C
0 .C
0.0
TOXR
0.0200690026
0.0012948595
0.0009081848
0.0007453170
0.0006230121
0.0005516736
0.0005211952
0.0004604242
C. 0004293468
0.0003967203
0.0003078190
0.0002976500
0.0003490720
C. 0004621690
0.0006267850
0.0006225290
0.0010064280
0.0011639520
C. 0012787460
0.001342337C
C. 0014061 790
0.0014702U4G
0.0015139260
C. 0015266070
0.0015061390
0.0014687500
0.0014396140
0.0014I034VO
0.0014437;" 60
0.001477244C
0.001563369C
0.00162P87CC;
0.001 7157350
0.001P3466SO
0.001V436760
0.0020H50530
C.00224M5020
0.0024'. '.01 00
(i.002M>402«tli
c.o(;2i'9r>5i<,<
LXR
100000.0000
97993.0997
97866.2124
97777.3318
97704.4567
97643. 5H57
97569.7183
97536.8550
97491.9949
97450.1371
97411.2817
97361.2967
97352.3111
97318.3262
97273.3507
97212.3812
97132.4212
97034.4701
96921.5267
96 797.5687
96667.6537
96531 .7216
90309.7926
9< 243.b656
Vt096.9390
9b9b2.01 15
9t>8 1 1 .Ocl?0
95673. 1510
9553H.21H5
95400. 2fc74
95259.35 7V
951 10.4324
94955.5099
94792.5914
946111. 67t<4
V.4.14. 7703
94 237.Mf,»'H
94»>/'>.9/4H
'i.t /''«.. 01, '« I
•M54(-.; 147
OXR
2C06.9003
126 .8673
H8 .C806
72.6751
60.6711
53.8674
50.8633
46.8600
41 .6579
36.8553
29.9B5C
26.9855
33.9630
44.9775
60 .9695
79.9600
97.9511
112.9435
123.9380
129.9350
135.9320
141 .S29C
145.9270
146.9266
144 .9275
140.9295
137.9310
134 .9325
137.9310
140.9295
J-.6.9255
154.S225
162 .91 H5
173 .91 30
183.9081
l<>(, .9015
<'ll .»-'>4ij
229 .t'H5C
/'i 9 .(• 750
t VO.H<.4«.
TLXR
98996.5499
97929.6561
97821.7721
97740. P943
97674.0212
97616.6520
97564.2866
97515.4250
97471.0660
97430.7094
97396.2892
97366.6039
97335.3197
97295.8394
97242.6659
97172.4012
97083.4457
96977.9984
96859.5577
96732.6212
96599.6877
96460.7571
96316.8291
96170.4023
96024.4753
95881.5467
95742.1165
95605.6847
95469.2530
95329.6227
95184.8952
95032.9712
94074.0506
94705 .6349
94526.7243
94336.3196
'»4131 .9?1«
•M911 .0323
9.16 71 . 1522
V.'4 10.7824
TXR
7072355.4529
6973358.9030
t«75429.2469
6777607.4746
(679866.5605
6582192.5593
6484575.9074
6387011.6208
6289496.1958
6192025.1298
6094594.4204
5997198.1312
5399831.3273
5602496.0076
5705200.1682
5607957.3022
5510784.9011
5413701 .4554
5316723.4570
5219863.6994
5123131.2782
5026531.5905
4930070.8334
4833754.0043
4737583.6020
4641559.1268
4545677.5801
4449935.4636
4354329.7789
4258860.5259
4163530.7032
4068345. 8060
3973312.8369
3B78438.7862
3783733.1513
3689206.4270
3594H70.1074
3500738.1857
340682 7. l*>34
J313I56.0012
EXR
70.723555
71.161734
70.253350
69.316756
68.366065
67.410394
66.447327
65.481716
64.512950
63.540446
62.565591
61.584702
60.602889
59.623877
56.651215
57.687686
56.734763
55.791529
54.855961
53.925557
52.997369
52.071293
51.147229
50.224022
49.3C0047
48.373755
47.444173
46.51J852
45.576837
44.642009
43.707314
42.774969
41.643942
40.914999
39.989263
39.066187
38.146768
37.231607
36.321633
35.417318
1XRIXR
4.94981
4.8965)
4.89111
4.88701
4.88371
1
4.88081
4.8 7821
4.87581
4.87361
4.87151
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
-------
CtNlKATF;tJ Lift UKU F UK 1H|. CI.M.KAL t'li^Ul A I 1 UN : UMll.l SlMt!,, 1969-71
X TO X«l
YEARS
40- 41
41- C
0.0062457010
0.0067761420
0.0073R43460
0.0080394040
O.COC7552080
O.OOS5<95430
0.0104293040
0.0113735170
0.0123481730
0.0134170850
0.0145143190
0.0157058340
0.0169497920
0.018290P890
0.0197391560
0.0213328730
0.0230609390
0.0249398750
0. 0269892640
0.02S18fc524C
0.0315150780
0. 0340055480
0.0366062210
0.0394373270
0.0426603900
0.0464370910
0.0507610340
0.055507494C
0.06C6015420
0.0659622230
0.0715430180
0.0773957380
IXN
0.0
C.O
0.0
0.0
0.0
0.0
0.0
0.0
o.o
0.0
0.0
0.0
0.0
C.O
o.c
0.0
0.0
0.0
0.0
0.0
0.0
0.0
C.O
0.0
0.0
0.0
0.0
0.0
C.O
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
o.c
0.0
1CXS
0.0031503«20
0.003396R270
0.0037104150
0.00403H9r,0
C.OC443',0240
C. 0041-369 3 1C
0.0052fU'3350
0.00573'>5fl90
0.00624?,70I(i
0.00677M4?(.
0.0073d43460
C.OOHOJ94040
O.OCM75520HC
O.OOS5695430
C.0104293H40
0.01137351 70
C.01234P1 730
0.0134170P50
0.0145143190
C.015705H340
0.0169497920
0.0 182906690
0.01973V1560
0.02133287JO
0.0230609390
0.0249398750
0.0269692640
0.02916E5240
0.0315150780
0.0340055460
0.0366062210
0.03943732 70
0.0426603900
0.0464370910
0.0507610340
0.0555074940
0.0606015420
C. 0659622230
0.0715430180
0.07739573BO
IXK
93275.3501
9t9Ml.497l
9t«i65.6551
9/321 .H271
91949.01 J5
91541 ..'I ?4
91 OVH.4JI3V
V0616.(.7VI'
9(!0'»6.9.>'yii
HV534.2212
hl.927.524«p
H1270.l"-»30
l!75(.l .20dO
»!(j 794.5914
b5964.006H
05067.4552
84099.9390
B3061.45H4
H1947.0I58
1*0757.6107
794H9.2450
76141.9189
76712.6337
751V8.3911
73594.1933
71897.0421
70103.9389
68211.8852
66220. B8 09
64133.9247
61953.0154
59685.1497
57331.3269
54HH5.5501
52336.8248
496R0.1535
46922.5327
44078.9548
41 171.4090
3H225.8021
im
293 .8530
315 .1)421
JS3.U280
3/2 .H135
4u7 .7961
442 .77H(,
4K1 .759 1
'j 19 . 74 (1C
?.«-2 . /III5
006 .t9M)
.6166
tOO .5H4C
t96 .55 16
907.5161
1038. 4P06
1114 .442t
1 1(19.4051
• ;<,&. 365fc
1347.3262
1429. 2P52
1514.2426
U04 .1977
It97 .1512
17S3.1032
1B92.0537
1991 .0042
2C86.9562
2180.9093
2267.8658
2353.8228
2445.7768
2548 .7253
2656 .6713
2757 .6208
2B43.577H
29C7.5458
2945.5269
2958.5204
11 XR
93128.4236
92H23.576 1
92493.7411
92135.4203
91745. 1155
91319.8282
90857.5593
90356. 8()9f
1.-B9815.5805
B9230.8729
H8599. 1888
H7916.0305
C7177.P997
86379.2991
H5515.7310
H45B3.6971
83580.6987
82504.2371
81352.3132
80123.4278
78815.5819
77427.2763
75955.5124
74396.2922
72745.6177
71000.4905
69157.9120
67216.3830
65177.4028
63043.4701
60819.0826
58508.2383
56108.4385
53611. 1B75
51008.4892
4B301 .3431
45500.7438
42625.1819
39698.6456
36746.6220
TXR
3219745.2188
3126616.7951
3033793.2190
2941299.4779
2849164.0577
2757418.7422
2666099.1140
2575241.5547
2484884.7449
2395069.1644
2305838.2914
221 7239.1026
2129323.0721
2042145.1724
1S55765.6733
1870250.1423
1785666.4452
1702085.7465
1619581.5094
1538229.1961
1458105.7683
1379290.1863
1301862.9101
1225907.3977
1151511.1055
1078765.4878
1007764.9973
938607.0852
871390.7022
806213.2994
743169.8293
662350.7468
623842.5085
567734.0700
514122.8825
463114.3933
414813.0502
369312.3064
326687.1245
286988.4790
EXK
34.518715
33.626226
32.739133
31.859199
30.986347
30.122157
29.266134
28.419068
27.580124
26.750321
25.929411
25.118587
24.318110
23.528484
22.750986
21.985495
21.232672
20.491884
19.763764
19.047483
18.343435
17.651092
16.970645
16.302309
15.646766
15.004310
14.375298
13.760169
13.158851
12.570778
11.995701
11.432505
10.881355
10.343962
9.823349
9.321920
8.840381
8.378427
7.934806
7.507701
1XRLXR
0.0
0.0
C.O
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
-------
GENERATED LIFE TABLE FOR THE GENERAL POPULATION: UNITED STATES, 1969-71
X TO X«T
TEARS
80- 81
81- 62
82- 63
83- 64
64- 85
85- 86
66- 67
67- 88
88- 89
89- 90
90- 91
91- 92
92- 93
93- 94
94- 95
95- 96
96- 97
97- 96
96- 99
99-100
100-101
101-102
102-103
103-104
104-105
105-106
106-107
107-108
108-109
109-110
TQX
0.0839450190
0.0912044050
0.096927660C
0.1069553060
0. 1154920040
0.1255978570
0.1374576090
0.14S7875580
0. 1616319830
0. 1728647690
0.1850059160
0.1968913820
0.2136738060
0.2285774150
0.2423460080
0.2577171570
0.2693423600
0.2806088680
0.2897884080
0.2979274610
0.3081180810
0.314*666670
0.3190661480
0.3314205710
0.3333333330
0.3333333330
0.3461538460
0.3529411760
0.3626363640
0.3571428570
IXR
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
c.o
0.0
0.0
c.o
0.0
0.0
0.0
0.0
0.0
TOXR
0.0839450190
0.0912044050
0.0989276600
0.1069553060
0.1154920040
0.1255978570
0.1374576090
0.1497875580
0.1616319830
0.1728647690
0.1850059160
0.1988913820
0.2136730060
0.22B5774I50
0. 2433460 080
0.2577171570
0.26934236CO
C.28060PB6UG
0.2897884080
0.2979274610
o.soeiifioein
0.314666667U
C.31906U460
0.33142F5710
0.3333333330
0.333333333C
0.3461538460
0.3529411760
0.3636363640
0.3571428570
LXR
35267.3618
32306.8424
29360.3161
26455.7687
23626.1839
2C897.5486
18272.8612
15761.1174
13400.2981
11234.3814
9292.3526
7573.2124
6066.9657
4770.6141
3680.1594
2784.6073
2066.9662
1510.2447
1086.4566
771.6141
541.7291
374.6K5
256.*)715
174.9125
1 16.9415
77.9610
51.9740
33.9830
21.VH90
13.9930
DXR
2960.5194
2946.5263
2904.5474
2829.5848
2728.6353
2624.6873
2511.7438
2360.8193
2165.9168
1942.0287
«T
1719. 1402
1506 .2467
1296.3517
1090.4546
895.5521
717.6411
556.7216
423.7881
314 .8425
229.HH50
166.9165
117.9410
81 .9590
57.971C
3H .9805
25.9670
17.9910
11 .9940
7 .9960
4.9975
TLXR
33787.1021
30833.5793
2790B.0424
25040.9763
22261.8662
19585.2049
17016.9893
14580.7078
12317.3398
10263.3670
8432.7825
(,820.0891
5418.7899
4225.3868
3232.3834
2425.7868
1788.6055
1298.3507
929.0354
656.6716
458.2708
315.8420
215.8920
145.9270
97.4513
64.9675
42.9785
27.9860
17.9910
11.4943
IXR
250241.8570
216454.7549
185621.1756
157713.1332
132672.1569
110410.2907
90825.0858
73806.0965
59227.3887
46910.0489
36646.6819
28213.8994
21393.6103
15975.0204
11749.6337
8517.2503
6091.4635
4302. P580
3004.5074
2075.4720
1418.8004
960.5296
644.6876
428.7955
282.8685
185.4173
120.4498
77.4713
49.4853
31.4943
EXR
7.095565
6.699966
6.322179
5*961389
5.615471
5.283409
4.970491
4.682923
4.419856
4.175579
3.943746
3.725486
3.52627«
3.348630
3.192697
3.058690
2.947055
2.649113
2.765419
2.689780
2.619022
2.562693
2.5C9767
2.451486
2.418889
2.378333
2.317500
2.279706
2.250455
2.250714
IXRLXR
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
FETAL RADIATION COSt TO TOTAL POPULATION > l.OREH PER INDIVIDUAL: KLLA1IVL MSK
-------
FETAL RADIATION OOSl TO TOTAL KiPULAl
PPPULA1 ION
NUMBER OF DOSE RAUSt ONE
RADIATION RISK MODlLt RELATIVE
ADOITICNAL RISKl NCNE
*** INPUT DATA *«*
DOSE ACE IMEKVAl
1.000000000 -1 - 0
CHILD ACE INTERVAL « 0-0
ADULT ACE INTERVAL * 0 - J 1C'
CUTPUT DATA BASED ON ACE IN1EKVAL * 0-110
ION = l.OKIM PEk INUIVIDUALi RELATIVE RISK
AT RISK: UNLRAL
RlFLktNCE TABLE INPUT SOURCE I DISK
ADDITIONAL ANALYSIS! S1ACES C CANCERS
ADDITIUNAl OUIPUt t LIFE TABLE
•»* OUTPUT DATA ***
NUMUR OF PKLPATURE DEATHS
DICMA^t |N PtPULATION LIFE
TUtAL YEARS OF LIFE LOST TO
AVLKACL YEARS OF LIFE LOST
CANCER FITAL CHILD
LATENCY PLATEAU DEATH RAH LATENCY HLAllAU OtATHRATE L
LEUKEMIA 0 10 0.500
ALL OTHER 0 10 0.500
CANCER FETAL
LEUKEMIA 16.36830
ALL OTHER 17.01355
TCTAL 33.401B5
TOTAL NUMBER OF INCREMENTAL DEATHS
0 0 0.0
0 0 C.O
CHILD ADULT
0.0 0.0
0.0 0.0
0.0 0.0
S
EXPECTANCY «
PREMATURE DEATHS «
PER PREMATURE DEATH •
ADULT
ATENCY PLATEAU DEATH
0 00
0 00
TOTAL
16.38830
17.01355
33. 40185
33.40181
33.40181
0.02249
2249.10962
67.33496
RATE
.0
.0
-------
GENERATED LIFE TABLE FOR THE GENIKAL POPULATION: UNITED STATES. 1969-71
X TO X«T
YEARS
0- 1
1- 2
2- 3
3- 4
/,- 5
5- 6
6- 7
7- 8
6- 9
9- 10
10- 11
11-12
12- 13
13- 14
14- 15
15- 16
16- 17
17- 18
18- 19
19- 20
20- 21
21- 22
22- 23
?3- 24
24- 25
25- 26
26- 27
27- 28
28- 29
29- 30
30- 31
31- 32
32- 33
33- 34
34- 35
35- 36
36- 37
37- 38
38- 39
39- 40
TOX
0.02CG196620
0.0012449016
O.OOC8 562144
0. COC695341 1
0.0005730322
0.0005016914
0.0004712119
O.OOC4304396
0.000379360!)
0.0003467330
O.OOC3078190
O.OOC2976500
O.OOC3490720
0.000462169C
0.0006267850
0.0008225290
0.0010084280
0.0011639520
0.0012787460
0.0013423370
0.0014061790
0.0014702840
0.0015139260
0.0015266070
0.0015081390
0.0014687500
0.0014396140
0.0014103490
O.C014437260
0.0014772440
0.0015633690
0.0016268700
0.0017157350
O.C01834669C
O.C019436760
0.0020G50530
0.0022465020
0.0024449100
0.002*640240
0.0028955160
IXR
0.0000337655
0.0000340P57
0 .0000340923
C. 0000340951
0.0000340971
0.0000342013
0.0000342C19
C.C000342C26
0.0000342034
0.0000342039
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
o.o
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
TOXR
0.02005 34? 75
0.0012789875
0.0006923067
0.0007294362
0.0006071294
0.0005358928
0.00050541 JH
0.0004646422
0.0004135639
0.0003829370
0.0003078190
0.0002976500
0.000349Q72C
0.0004621690
0.00062C7850
0.0006225290
0.0010064260
C. 0011639*20
0.00127H7460
0.0013423370
0.0014061 JSO
0.0014702840
C.OC15139260
0.0015266070
0.00150B1390
C. 0014667500
0.0014396140
0.0014103490
0.0014437260
0.0014772440
0.00156336SO
0.00162B07CO
C.001715735C
0.00163466SC
C. 0019436 760
0.00208^0530
0.00224H5020
0.00244491CO
0.0026640240
0.00289551 to
LXR
100000.0000
97994.6572
97869.3; 3
97781.9939
97710.6661
9765».3451
9759V. 0145
97549.6666
97504. 3C09
97464.0J66
97426. M40
97396.724;
97367.7341
97333.7457
9726P.7611
97227. 7620
97147. Uo93
97049.8427
9t.936.UHI4
96C12.9237
96682. 96111
96547.0146
9640^.0630
96259.1129
9C 1 12. 1631
9'.- 96 7. 2 126
958*6.2607
956H8.3079
95553.3540
95415.4011
95274.4493
951^5.5002
91970.5531
94807.6068
94633.668?
94449.7310
94?b2.7983
94C40.H707
9 38 10.9493
93561 .0347
OXK
2C05.3426
Ii5.3339
87.3294
71 .3257
59.3230
52 .3306
49.3279
45 .3257
40.3243
37.3226
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29.989P
28 .9901
33.9883
M4 .9846
60.9791
79 .9727
97 .9666
112.9614
123.957C
129.955(
135.9536
141 .9515
l',5.9501
146.9498
144 .9505
I40.951fi
137.9526
134 .9539
137.952V
140.9518
148 .9491
154 .94 1}
162 .S443
17J.940t
Ih3.937i
196 .9327
ill .9276
229.92 15
24<) .9146
£ 70. 90 75
TLXR
9B997.32B6
97931.9903
97825.6566
97746.3310
97681.0066
97625.1798
97574.3505
97527.0237
97484.1967
97445.3753
97411.7191
97382.2291
97350.7399
97311.2534
97258.2715
97187.7956
97098.8260
96993.3620
96874.9025
96747.9459
96614.9914
96476.0318
96332 .0860
96185.6360
96039.6878
95896.7367
95757.2843
95620.8310
95484.3776
95344.9252
95199.9747
95048.0266
94889.0810
94720.6385
94541 .6996
94351 .2647
94146.8345
93925.9100
93685.9920
IXR
7073398.3900
6974401.0614
6876469.0711
6778643.4125
6680897.0815
6583216.0749
6485590.8951
6368016.5446
6290489.5208
6193005.3221
6095559.9468
599B148.2277
5900765.9986
5B03415.2586
5706104.0052
5608845.7337
551 1657.9381
5414559. 1121
6317565.7501
5220690.8475
-
5123942.9016
5027327.9103
4930P51.8714
4834519.7835
4/38334.1455
4642294.4576
4546397.7210
4450640.4367
4355019.6057
4259535.2282
4164190.3029
4068990.3282
3973942.3015
3879053.2206
3784332.5821
3689790.8624
3595439.6177
3501292 .7832
3407366.8732
93425.5809 | 2313660.8812
EXR
'
70.733984
71.171236
70.261741
69.324046
68.374285
67.415519
66.451397
65.484747
64.514956
63.541441
62.565591
61.584702
60.602889
59.623877
58.651215
57.687686
56.734763
55.791529
54.855961
53.925557
52.997369
52.071293
51.147229
50.224022
49.3C0047
46.373755
47.444173
46:511852
45.576637
44.642009
43.707314
42.774969
41.843942
40.914999
39.989283
39.066187
38.146766
37.231607
36.321633
35.417318
IXRLXR
3.37661
3.34021
3.33661
3.33391
3.33171
1
3.33981
3.33811
3.33641
3.3350)
3.33371
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
-------
GENERATED LIFE TABLE FOR THE CIMKAL POPULATION: UMUO STATES. 19(9-71
X TO X«T
YEARS
40- 41
41- 42
42- 43
43- 44
44- 45
','- 46
46-47
47- 48
48- «9
.9') 35
2958 .989 1
TLXR
93143.1774
92838.2816
92508.3943
92150.0167
91759.6501
91334.2954
90871 .9534
90371.1245
B9829.8094
89245.0092
68613.2251
87929.9585
67191.7108
86392 .9637
85529.2787
64597.0972
83593.9399
62517.3078
81365.2014
U0136.1213
78626.06£2
77439.5426
75967.5455
74408. 07P3
72757.1424
71011.7367
69168.8683
67227.0317
65187.7285
63053.4577
60826.71 77
58517.5074
56117.3274
53619.6808
51016.5701
48308.9952
45507.9522
42631 .9348
39704.9348
36752.4435
'
. TXR
3220255.3003
3127112.1229
3034273.8413
2941165.4470
2849615.4303
2757855.7802
2666521.4848
2575649.5314
2485278.4069
2395448 .5975
2306203.5882
2217590.3632
2129660.4047
2042468.6939
1956075.7103
1870546.4315
1785949.3343
1702355.3944
1619838.0867
1538472.8653
1458336.7640
1379508.6957
1302069.1531
1226101.6076
1151693.5292
1078936.3869
1007924.6482
938755.7799
871528.7482
806341.0197
743287.5620
682458.8443
623941.3369
567824.0095
514204.3287
463187.7585
414678.7634
369370.81 12
326730.8764
2870.13. 9416
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EXR
34.516715
33.626226
32.739133
31.8591S9
30.986347
30.122157
29.266134
28.419060
27.580124
26.750321
25.929410
25.116567
24.318110
23.528484
22.750985
21.985495
21.232672
20.491884
19.763764
19.047483
18.343435
17.651092
16.970645
16.302309
15.646766
15.004310
14.375298
13.760169
13.158851
12.570777
11.995701
11.432505
10.881355
10.343962
9.823349
9.321919
8.840381
0.378427
7.9348C5
7.007701
1
IXRLXR
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
-------
GENERATED Lift TABLE FOR THE GENERAL POPULATION! UNITED STATES, 1969-71
X TO X«T
YEARS
80- 01
81- 82
82- 93
83 04
84- «5
85- 86
86- 87
87- 88
88- 89
89- 90
90- 91
91- 92
92- 93
93- 94
94- 97-
95- 96
96- "'
97- <8
91 •• 99
•; -oo
KO T!
i« :•:.}
n. --106
106-107
107-108
108-109
109-110
10X
0.0839450190
0. 091204*1050
0.0989276600
0.1069553060
0.1154S20040
0.1255978570
0.1374576090
0. 1<,97875560
0.1616319830
0.1728647690
0.1850059160
0.1988913820
0.2136738060
0.2285774150
0.2423460080
0.- •177171570
0.26S342360C
0.2806088680
0.2897884080
0.2979274610
0.30811R0810
0.3146166670
0.3190661480
0.33142n571P
0.3333333330
0.3323333330
0.3461538460
0.352941 1760
0.36J6363640
0.357142C570
1XR
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
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0.0
o.c
0.0
0.0
0.0
0.0
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TOXR
0.o'839450190
0.0912044050
0.0989276600
0.106955306C
0.1154920040
C. 12559 78570
0.1374576090
0.14978755PO
0.1616319830
0.1726647690
0.1850059160
0.1986913820
0.2136738060
0.2285774150
0.2433460060
0.2577171570
0.2693423600
0.2b060PB6BO
0.2897864080
0.2979274610
0.3081 180810
0.31466t6670
0.31906614BO
0.3314285710
C. 3333333330
0.3333333330
C. 3461538460
0.3529411 760
0.3636363640
C. 3571428570
LXR
35272.9490
32311.9606
29364.9675
26459.9599
23629.9268
20900.8592
1P275.7561
15763.6144
13402.4211
11236.1612
9293.8248
7574.<»122
6067.9269
4771.3699
3680.7425
2785*0485
2067.2937
1 5l0.4b39
1086.6288
771.7363
541.8149
374.6719
256.9122
174.9402
1I6.96UO
77.9734
51.9822
33.9b64
21.9925
13.9952
DXR
2960.9884
2946.9931
2V05.C075
2830.0331
2729.0676
2625.1031
2512 .1417
2361 .1933
2166.2W9
1942 .3364
1719.4126
1506.«.853
1296. 557C
1090.6274
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717.7546
556.f>09fc
423.6552
314.J<924
229.V214
166.9430
117 .959 1
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57 .9802
38 .9067
25.V911
17.9939
11 .S95S
7.9973
4 .9983
TLXR
33792.4548
30838.4640
27912.4637
25044.9434
22265.3930
19588.3077
17019.6852
14583.0177
12319.2911
10264.9930
8434.1165
6821.1695
5419.6484
4226.0562
3232.8955
2426.1711
17PB.8868
129*1.5563
929.1825
656.7756
458.3434
315.8921
215.9262
145.9501
97.4667
64.9778
42.9853
27.9904
17.9939
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TXR
250281.4981
216489.0433
185650.5793
157738.1156
132693.1722
110427. 77S2
90839.4715
73819.7863
59236.7686
46917.4775
36652.4845
28218.3660
21397.1965
15977.5481
11751.4919
8518.5964
6092.4253
4303.5365
3004.9802
2075.7976
1419.0220
960.67H6
644. 786*
428.8603
282.9102
185.4435
120.4657
77.4804
49.4899
31 .4961
EXR
7.095565
6.699966
6.322179
5.961369
5v615471
5.2834C9
4.970490
4.682923
4.419856
4.175579
3.943746
3.725486
3.526278
3.348629
3.192696
3.058689
2.947054
2.849111
2.765416
2.689776
2.619016
2.5626B5
2.509754
2.451468
2.418862
2.378293
2.317439
2.279613
2.250311
2.250468
1XRLXR
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
•«« END OF RUN ***
-------
Sample Problem 3.
This problem addresses the adult stage radiation exposure discussed
in section U. 3b. The four cases analyzed examine the effects of
absolute and relative risk, and 30 and life plateau periods on the adult
exposure.
The title and case data for the first absolute risk case are input
followed by the two cancer data cards. Since the second case differs
only by the all other cancer plateau period, there is no need to inpjt
the case data again. Setting CASREP equal to 2 on the all other cancer
card causes the cancer cards for the second case to be input. These are
used with the retained case data to generate the second case results.
Since CASREP is 1 on the second case's all other cancer card (if
there is more than one cancer card, the CASREP value on the last card is
used), new case data are input. Use of CANREP allows cancer mortality
data to be input and retained for subsequent relative risk cases.
Only summary tables are output for these cases.
Input Data:
A3U1T P.ADI \7lur; !))5E TO T-JT\L PJP'JLAT Iu:i = 1. 0^n,'P!:RSO'J/AGE20-3'\ ABSOLUT I: ".IS!:
000000
0 1.0 0.0 o.O
3121 '.11
30
O
10
0
0
2 !">
0
0
12
•> •>
12
12
0.0
0
ALL 07MII".
ALL 07:1 P.".
0
u
0
0
A~»ULT •
3131411
30
2
0
11 1
10
0 0 0
0 0.0
LCI.T.V: !!'-.
4 000035367
00003545/* 0000/43371
00^590330 00/74083-'.
21 2 ALL 07'IKR
0000371)31 00003255-'.
O007332'il 001119068
01159633& 01M24127
22 1 LEUKii'lIA
12 2 ALL 07ili:i
TO T:)T\L
20 20
0 0
0.0
0
000021347
000062375
000740334
0
00.1032216
002196321
014124127
0
0
* i*
0
0
0
0
••'.0
0.0
0.0
0.0
0.0
0
0
0.0
0 0.0
000020230
000100071
000740334
0 0.0
000052229
003419671
014124127
0 0.0
0 0.0
n
o
o
0
L • «.
0
0
0.0
0
0
0
0
0.0
2
15
o
15
0.0
0 0
000016544
000140039
000740884
0 0
O00071.'il8
004864605
014124127
0 0
0 0
0.0
0.0
0.0
0 0
1.0
0.0
0.0 2
00001^845
000225118
0007408:54
0.0 15
000110TJ53
006533333
014124127
0.0 2
0.0 15
25
3J
25
1 10
J°t
o
0.0
1.0
5.0
1.0
5.0
P.ELMIVL
0
0.0
25 0.02
000021354 000028818
000348S96 0004f.7433
30 .002
000196325 000339229
003509686 010022733
25 0.02
110 .002
65
-------
ADULT RADIATION DCS? TO TOTAL POPULATION * 1.OFLH/PrPSON/AGE20-30, ABSOLUTE FISH
POPULATION ^^ RISK:
NUMBER OF DOSE RATES: ONE
RADIATION RISK MODEL: ABSOLUTE
ADDITIONAL RISK: NONE
PEFEFEHCE TABLE INPUT SOURCE: DISK
ADDITIONAL ANALYSIS: STAGES t CANCERS
ADDITIONAL OUTPUT: NONE
* **
INPUT DATA
*»«
DOSS AGE INTERVAL
1.000COOOOO 20 - ?0
CHILD AGE INTERVAL = C - 10
ADULT AGE INTERVAL = 10 - 110
OUTPUT DATA BASED ON AGE INT'-PVAL = 20 - 110
***
OUTPUT DATA
NUMBER OF PSfMATURS DEATHS =
DECREASE I!) POPULATION LIFE EXPECTANCY =
TOTAL YFARS OF LIPS LOST TO PREMATURE DEATHS =
AVSKAGS YEARS OF LIFE LOST PER PREMATURE DEATH
151.52635
0.0381P
3809.50391
25.1U085
CANCER
LEUKEMIA
ALL OTHER
LATENCY
0
0
FETAL
FLAT5AII
C
n
DEATH RA~E
0.0
0.3
LATENCY
0
0
CHILD
PLATEAU DEATH RATE
0.0
0.0
ADULT
LATENCY PLATEAU DEATH RATE
2
15
25
30
1.000
5.000
CANCER
LEUKEMIA
ALL OTHER
TOTAL
FETAL
0.0
0.0
0.0
CHILD
O.n
ADULT
23.18555
123.36U95
1U6.55050
TOTAL
23.18555
123.36U95
1U6.55050
TOTAL NUHES3 OP INCREMENTAL DEATH!-
151.52635
-------
ADULT RADIATION DCSE TO TOTAL POPULATION = 1.Op2M/PERSON/AGZ20-30, ABSOLUTE RISK
NUMBER OF DOSS RATES: ONE
RADIATION RISK MODEL: ABSOLUTE
ADDITIONAL RISK: NON2
POPULATION AT PISK: GENERAL
PK:-T.PSNCE TABLE INPUT SOURCE: DISK
ADDITIONAL ANALYSIS: STAGES 6 CANCERS
ADDITIONAL OUTPUT: NONE
*«* INPUT DATA *•«
DOSE AGE INTERVAL
1.000000000 20 - 30
CHILD AGE INTERVAL = 0-10
ADULT AGE INTERVAL = 10 - 110
OUTPUT DATA BASED ON AG£ INTEPVAL = 20 - 110
OUTPUT DATA
NUMBER OF PREMATURE DEATHS =
DEC33A5E IN POPULATION LIFE EXPECTANCY =
~0~AL YEARS OF LIFE LOST TO PREMATURE DEATHS =
AVERAGE YJ5ARS OF LIPS LOST P5H PREMATURE DEATH
190.36925
O.OU137
U136.90625
21.73096
CANCHR
LEUKEHIA
ALL OTHER
FETAL
LATENCY PLATIAU DEATH RAT£
1 0 0.0
LATENCY
0
"I
CHILD
PLATEAU
C
n
DEATH PATE
•">. 0
ADULT
LATENCY PLATEAU DEATH RATE
25
110
1.000
5.000
CANCF.R
LEUKEMIA
AIL OTHE?
TOTAL
FETAL
0.?
0.0
0.0
T . n
1.0
ADULT
21. 18555
U0.9J2U7
1Hu. 11801
TOTAL
23.1B555
160.932U7
1BU.11801
TOTAL NUMBER OF INCREMENTAL DEATHS
190.36925
-------
ADULT RADIATION DCSf. TO TOTAL POPULATION = 1. Of RM/PEPSQN/AGE20- 30, RELATIVE RISK
OF DDSE PATES: ONE
PAOUriON PISK HODSL: RELATIVE
ADDITIONAL ?!SK: NOll*
POPULATION AT RHK: GENfAL
REFERENCE 7ADLF INPUT SOURCE: DISK
ADDITIONAL ANALYSIS: STAGES 6 CANCERS
ADDITIONAL OUTPUT: NONE
INPUT DA^A
LJOJ"
1.OCOOOOT01
CHILD A.iJF. INTEPVAL =
ADULT AGE INTERVAL =
OUTPUT i:A"A BASED ON "VGE
»G!T INTERVAL
20 - 30
0-10
10 - 110
INTERVAL 20 - HO
OUTPUT DATA
NUflHEP OF PR:;HATIIR~ DEATHS =
DECSSASE IN POPULATION LIFF EXPECTANCY =
TOTAL YEP.T«-~"OF LIFF LOST TO PPFHATURE DEATHS =
AVERAGE YEARS OF LIFE LOST PER PREMATURE DEATH
168.92007
0.0338U
33BU.33057
20.03510
CANCER
LEUKEMIA
ALL UTIIEH
LATENCY
FETAL
TLAT^AU
DEATH HATE
0. 0
0.1
LATENCY
0
0
CHILD
PLATEAU
DEATH RATE
1.0
0.0
ADULT
LATENCY PLATEAU DEATH RATE
2
15
25
30
0.020
0.002
CAHCSS
L2I1K5.1IA
ALL OTH2.1
TOTAL
FETAL
O.i)
0.0
0.0
CHILD
0.0
0.0
0.0
ADULT
15. I
1«7.9hU38
163.37295
TOTAL
15.U0857
1"47. 96U38
1S3. 37295
TOTAL NUHBE? OF INCPEflENTAL DEATHS
168.92007
-------
ADULT RADIATION DCS?. TO TOTAL POPULATION = 1 . "PSI/PKRSnN/AGEZO- 3
RELATIVE RISK
POPULATION AT RISK:
NUMUER OF DOSS SATSS: ONE
9ADIATION RISK HODEL: RELATIVE
ADDITIONAL RISK : NONE
RETEPENCE TABLE INPUT SOURCE: DISK
ADDITIONAL ANALYSIS: STAGES 6 CANCERS
ADDITIONAL OUTPUT: HONE
*•* INPUT DATA ***
DOSS AGE INTERVAL
•>. 000000000 20 - 30
CHILD AGE INTERVAL = 0-10
ADII-T AGE INTERVAL = 10 - 110
OUTPUT DATA BASSE ON AGE INTERVAL = 20 - 110
OUTPUT DATA
NUHUER OF PRErATUPE DEATHS = 325.95239
D=:CR2/,SE IN POPULATION LIFE EXPECTANCY = O.OU619
TOTAL YFA*S OF LIFE LOST TO PREMATURE DEATHS = 14619.00391
AVERAGE YEAP5 OP LIFE LOST PER PREMATURE DEATH = 1U.17079
CANCS3
LLUKEMIA
ALL OTHER
LATENCY
0
o
FETAL
PLATEAU DEATH RATE
LATENCY
CHILD
PLATEAU
1.
DEATH PATE
0. T
0,0
LATENCY
2
15
ADULT
PLATEAU
25
110
DEATH FATE
0.020
0.002
CANCER
LEUKEMIA
ALL OTHER
TCTAL
FETAL
0.0
CHILD
0.0
i. 1
1.0
ADULT
15.141857
299.9U3«5
31ri.252T2
TOTAL
15.00857
299.8U3«5
315.25202
TOTAL NU.1BE3 OF INCHEMENmAL DEATHS
325.95239
i)ND OF 3'JN
-------
Sample Problem 1.
The last problem considered in the text concerns combining accident
and radiation risk and is discussed in section H.U. In this example,
the radiation exposure interval partially overlaps the first of two
accident exposure intervals. The effects are calculated using the male
population, for which the BEIR absolute risk estimate for all other
cancers has been reapportioned to eliminate the risk of death from
breast cancer.
Use is made of the code's multiple accident risk provision to
accommodate the two different accident exposure intervals and rates.
Both radiation and non-radiation risk summaries are provided in the
summa ry ta ble.
Input Data:
TOTAL
312K.21
65
0.
22 1
00 •>
22 1
12 2
TOTAL
3121411
65
0.
22 1
22 2
22 1
12 2
TOTAL
3131411
65
0.
21 1
PJPL"L.\TION:
2 10
000
0 0.0
LCUKF/1I\
ALL OT.-lLl
LEUKT.ML\
ALL OTiiE't
OCC UPA'T
13
0
<0
IONAL
18
0
.0
0
0
0
o
POPUL\TIO:!: OCC'JPXTION\L
2 1.
0
0
o
15
2
15
nin
0
0
2
IMC
0
0.0
25
110
25
30
INC
0
0.0
25
110
25
30
ING
0
0.0
25
in - 65
0
5.0
2.0
1.0
2.0
1.0
n - 55
0
1.0
2.0
l.n
2.0
1.0
IS - 65
0
5.0
0.05
ACL
0
0.0
2
15
2
15
•\CE
0
0.0
2
1.5
2
15
\C1
0
0.0
T
INT
0
0.0
25
110
25
3.1
INT
0
0.0
25
110
25
30
INT
0
0.0
25
ErtVAL
0
1.0
5.0
1.0
5.0
'•.'VtfAL
0
1.0
5.0
1.0
5.0
E;lV\L
0
0.02
0.0
0.0
0.0
0000311S4 000035367
000035454 000043871
000590330 000740834
21 2 ALL OTUCR
000037031 000032554
000758201 001319668
011596386 014124127
22 1 LEUK'VIIA
12 2 ALL OTME^
TOT\L POPULATION:
2 10
000
0.0 0.0
22 1 LEUKK 1I\
22 2 ALL OTIIE^
22 1 LEUIXIIA
12 2 ALL OTIIi:*
*** EN'^ OF .IUN
000021347 000020230 000016544
000062375 000100071 000140089
000740384 0007408S4 OOD740W4
0 0 0.0 15 110
000032216 000052229 000071818
002196321 003419671 004S64605
014V24127 014124127 014124127
3131411
65
OOOU6345 00002185'* 00002331 S
000225118 000348390 000467433
0007408H4
0.02 15 110 .002
000110853 000196325 000389229
006533333 003509635 01D022733
014124127
0.0
OCC U1'\T
lo
0
0
0
0
IONAL
111
0
.0
0 ,
0
0
0
0
0
0.
0.
0
0
EXPOSURE
0
0
0
0
0
0
0.
0.
0.
0.
0.
0
0
0
0
0
0
0
n
15
DIR
0
0
2
15
2
15
25
30
I;;G
0
0.0
25
110
25
30
0.
0.
18
1
0.
0.
0.
0.
05
02
- 65
0
.0
05
02
05
02
2
15
ACE
0
0.0
2
15
2
15
25
30
FIT
0
0.0
25
110
25
30
0.02
.002
ERVAL
0
0.02
.002
0. 02
.002
**.;-
70
-------
(Hilt POP: ACC. MSK-O.O005 FOk 25-35; 0.0002 F UK 3*-4$; COSE=3.0REM FOR 20-30
POPULATION A1 KISK: MALI
NUMBER OF OOSL RAILS: Or>E
RADIATION RISK MOUELt AfcSOLUU
ADDITIONAL RISK: ACCIDENT HULTIP LE)
REFERENCE TABLE |NHj| SOURCE i DISK
ADDITIONAL ANALYSIS! STAGES t CANCERS
ADDITIONAL OUTPUT! NONE
»«« INPUT DATA ««*
OOSE
3.0COOOOOOO
CHILD ACL INTLKVAL
ADLLT ACL INHKVAL
CUIPUT DATA BASED
AGE
ACL INURV/l =
INTLRVil
^0 - JO
0 - 1C
10 - 1 10
20 - 110
*«* OUTPUT DATA •*•
NUKCLR UF JKIKATUkl CEAThS '
MIKI.AK II. MHLLATION LIFl EXPECTANCY •
TLTAL innti UF LIFE LOST Tr PREMATURE DEATHS «
AVIKACL YLAkS OF LIFl LOST FER PREMATURE DEATH
1061.11230
0.34428
34^28.3125
32.44548
CANCIR
LtUKIMl A
ALL (THLR
Fl TAl
LATtKCY PL*TLAU lilATH MiTI
0
0
C.U
0.0
C» ILU
LAHNtY ^L/.TlAU hIATHRATt
C.O
C.O
AOULT
LATENCY PLATEAU DEATH RATE
2
15
25
110
1 .000
3.500
CANCIR
ALL
TOTAL
Fl TAl
C.O
(. .1
(i.l:
Chilli
0.0
0 .0
ADULT
(jfc.93t.74
<'*9.6H?tf2
^06.61907
TdTAL
66.93624
2c'9.6b2B2
366.61907
NCMFI.R HF rtATHS CAUSIO uv MCN-KADIATIUN
653.39601
TOTAL NIIMOI K OF INCKLMINTAL
1061.11230
»««
111 RUN
-------
Sample Problem 5.
This problem examines the exposure of the female population to a
lifetime annual dose of 0.5 rem. In addition to the summary and life
tables, two tables are provided which show the age distribution of the
radiation deaths by stage of exposure and cancer type.
Input Data:
c
21
12
12
12
12
12
i:
*
IIIV>
2 I 4 '. .
110
1
1
'3
4
5
0
X*
1 6 10
000
0.0 0.0
L;:UU: \i\
3P.::,\:-,T
Ll^O
01 U/S701.
^o::2
ALL OT'li:"..;
C'.'L) Or "U"! ** :
r T / \ • 1 '"^ i "" '-1*
L 1 V / * ^J.J J 1_<
0 0
•I u
u.O
0
0
0
0
0
0
k *
TO r
0
•/
,"i
0
0
0
(1
0
F.-L\Lr.
0
0
0.0
0.0
J.O
'J.O
0.0
0.0
0.0
P'J?:J
0
0
2
0
0
0
0
15
L\Tlo;l =
0
0.
u. o
9 c -i
0 0.
0 0.
"i J.
0 0.
1 U 1 .
a
o
5
0
J
0
u
0
0
5--1
0
u.O
2
15
15
15
15
15
n
0.0
25
1 lf?
110
110
110
llu
•,VJ/AC:::I-I 10
0
0. u
1.0
1.0
1.3
1.0
0.2
1.0
72
-------
CHILD AND ADULT RADIATION DOSE TO
POPULAT
NUMBER OF DOSE RATESt ONE
RADIATION RISK MODELS ABSOLUTE
ADDITIONAL RISK! NONE
«*« INPUT DATA «»«
DOSE ACE INTERVAL
0.500000000 0-110
CHILD ACE INTERVAL - 0-10
ADULT ACE INTERVAL •= 10-110
OUTPUT DATA BASED ON ACE INTERVAL = 0 - 110
CANCER FflAl
LATENCY PLATEAU DEATH RATE
LEUKEMIA 0 0 0.0
BREAST 0 0 0.0
LUNG 0 0 0.0
Cl W/STOM. 0 0 0.0
RONE 0 0 0.0
ALL OTHERS 0 0 0.0
CANCER FETAL
LEUKEMIA 0.0
BREAST 0.0
LUNG 0.0
Cl M/STOM. 0.0
BONE 0.0
ALL OTHERS 0.0
TOTAL 0.0
TOTAL NUMBER OF INCREMENTAL OEAIHS
FEMALE POPULATION = 0.5REM/PERSON/ACEO-110
ION AT RISK: FEMALE
- REFERENCE TABLE INPUT SOURCE: DISK
ADDITIONAL ANALYSIS: STACES C CANCERS
ADDIIIONAL OUTPUT: NONE ONE TWO
•«» OUTPUT DATA «•*
NUMBER OF PREMATURE DEATHS *
DECREASE IN POPULATION LIFE EXPECTANCY *
I DIAL YEARS OF LIFE LOSI TO PREMATURE DEATHS «
AVER ACE OfEARS OF LIFE LOST PER PREMATURE DEATH =
CHILD ADULT
LATENCY PLA1EAU DEAIH RATE LATENCY PLAIEAU DEAIH
2 25 2.000 2 25 1
0 0 0.0 15 110 3
0 0 0.0 15 110 1
0 0 0.0 15 110 1
0 0 0.0 15 110 0
15 110 1.000 15 110 1
CHILD ADULT TOTAL
24. 31237 63.25590 67.56827
0.0 208.22997 208.22997
0.0 90.2329* 90.23294
0.0 69.40997 69.40997
0.0 13.BB200 13.88200
27.47919 69. 40997 96.88916
51.79156 514.42075 566.21231
566.20532
566.20532
0.1272B
12728.4727
22.48030
RATE
.000
.000
.300
.000
.200
.000
-------
GENERATED LIFE TABLE FOR Ft MALES: UNIItO SIATES 1969-71
X TO X«T
YEARS
0- 1
1- 2
2- 3
3- <•
4- 5
5- 6
6- 7
7- 6
8- 9
9- 10
10-11
11- 12
12-13
13- 14
14-15
15-16
16- 17
17- Ifl
1H- 19
19- 20
20- 21
21- 22
22- 23
23- 24,
24- 25
25- 26
26- 27
27- 28
28- 29
29- 30
30- 31
31- 32
32- 33
33- 34
34- 35
35- 36
36- 37
37- 38
38- 39
39- 40
TO.X
0.0l7
IXR
100000.0000
98254.0000
98139.0000
98063.9510
9H004.8040
97954.5592
97912.2167
97174.7766
97840.2390
97809.6037
97780.8711
97755.0410
97729.1136
97701.1135
97669.0654
97627.9700
97578. H030
97520.5406
974?>b.lH30
97386.7304
97316.1827
97244. 5«.02
97171. B031
970V6.97I9
97020.0470
96942.0284
96861.78)4
96778.1802
96692.2678
96601. 096B
96505.6678
96402.9835
96293.0455
96173.8566
96046. 41B5
95906.7356
•)S756.B09H
95542.6466
95415.2251
95721. '-'HO
DXR
1746.0000
115.0000
75.0490
59.1470
50.2448
42.3425
37.4401
34.5377
30.6352
28.7326
25.8301
25.9274
28.0001
32.0481
41.0955
49.1670
58.2624
65.3576
68.4527
70.5477
71.6425
72.7371
74.8312
76.9249
78.0186
80.2449
83.6032
85.9124
91.1711
95.4290
102.6843
109.9380
119.1889
127.4381
139.6828
149.9259
164.1632
1 77.4215
193.6971
2 10-9*. 72
TLXR
99127.0000
98196.5000
98101.4755
98034.3775
97979.6B16
97933.3880
97893.4967
97857.5078
97824.9213
97795.2374
97767.9561
97742.0773
97715.1136
97685.0895
97648.5177
97603.3865
97549.6718
974fi7.86l8
97420.9567
97351.4565
97280.3614
97208.1716
97134.3875
97058.5094
96981.0377
96901.9059
96819.9818
96735.2240
96646.6823
96553.3823
96454.3257
96348.0145
96233.4510
961 10.1375
95976.5770
95831.7727
9V674.72B2
95503.93-i9
95318.3766
<>M K.0444
TXR
7452295.7044
7353168.7044
7254972.2044
7156R70.7289
7058836.3514
6960856.6698
6862923.2819
6765029.7852
6667172.2774
6569347.3561
6471552.1187
6373784.1626
6276042.0853
6178326.971 7
6080641 .8823
5982993.3645
5885389.9781
5787B40.3063
5690352 .4445
5592931 .4878
5495580.031 3
5398299.6698
5301091 .49H2
5203957.1107
5106898.6013
5009917.5636
4913015.6578
4816195.6759
4719460.4519
4622813.7696
4526260.3873
4429806.061 7
4333458.0472
-------
GENERATED LIM 1ABLE FOR FEHAIESt UNIIED S1AIES 1S69-71
X TO JUT
YEARS
40- 41
41- 42
«-2- 43
43- 44
44- 45
45- 46
46- 47
47- 48
48- 49
49- 50
50- 51
51- 52
52- 53
53- 54
54- 55
55- 56
56- 57
57- 58
5B- 59
59- 60
60- 61
61- 62
62-63
63- 64
64- 65
65- 66
66- 67
67- 68
68- 69
69- 70
70- 71
71- 72
72- 73
73- 74
74- 75
75- 76
76- 77
77- 78
78- 79
79- 80
TQX
0.0023238642
0.0025189B75
0.0027261048
0.0029772416
0.0032411711
0.0035395614
0.003R517061
0.0041565BBO
0.0044759214
0.004B427214
0.0052255364
0.0056578957
0.0061 OB 3096
0.0065998588
0.0071118783
0.0076792519
0.0082930490
0.0089442198
0.0096120126
0.0103561843
0.0111339974
0.0119957204
0.0129828351
0.0141035793
0.0153800808
0.0167745887
0.0183112987
0.0200436940
0.0219392713
0.0240723971
0.0263198593
0.028786B059
0.0316533099
0.03502506 38
0.0389227071
0.0432481585
O.O4 7888 3993
0.052937H084
0. 058400 7B70
0.0643196602
IXR
0.0000677938
0.0000710329
0.0000742708
0.0000775064
0.0000807406
0.0000839725
0.0000872029
0.0000904325
0.0000936605
0.0000968851
0.0001001077
0.0001033264
0.0001065428
0.0001097555
0.0001129654
0.0001161704
0.0001193707
0.0001225668
0.0001257596
0.0001289454
0.0001321264
0.0001352993
0.0001384605
0.0001416091
0.0001447426
0.0001478631
0.0001509683
0.0001540533
0.0001571196
0.0001601606
0.0001631851
0.0001661838
0.0001691402
0.0001720430
0.0001748879
0.0001776813
0.0001B04316
O.OOOIB312B2
0.0001857689
0.0001883475
lUXR
0.0023916580
0.0025900204
0.0028003756
0.0030547480
0.0033219118
0.0036235339
0.0039389089
0.0042470206
0.0045695619
0.0049396065
0.0053256441
0.0057612221
0.0062148524
0.0067096143
0.0072248437
0.0077954223
0.0084124197
0.0090667866
0.0097377722
0.0104851296
0.0112661238
0.0121310197
0.01 31212957
0.0142451884
0.015524B234
0.0169224519
0.0184622670
0.0201977473
0.0220963910
0.0242325577
0.0264830444
0.0289529897
0.0318224500
0.0351971068
0.0390975950
0.0434258398
0.04806BB309
0.0531209366
0.05H5865509
0.0645080077
LXR
95010.5608
94783.3280
94537.8373
94273.0958
93985.1153
93672.9050
93333.4781
92965.8460
92571.0181
92148.0073
91692.8324
91204.5090
90679.0596
90115.5026
B9510.B623
88864.1603
88171.4267
87429.6916
B6636.9B53
85793.3341
B4893.779B
83937.3560
82919.1103
81831.1041
80665.4046
79413.0884
7B069.2243
76627. BB94
75080.1787
73421.1777
71641.9948
69744.6966
67725.3792
65570.1917
63262.3106
60788.9064
5B149.0971
55353.9380
52413.4850
49342.7597
OXR
227.2328
245.4908
264.7415
287.9806
312.2103
339.4269
367.6321
394.8279
423.0108
455.1743
4,
488.3234
525.4494
563.5570
604.6403
646.7020
692.7337
741.7350
792.7064
843.6512
899.5542
956.4238
1018.2457
1088.0062
1165.6995
1252.3162
1343.8642
144 1.3349
1547.7107
1659.0010
1779.1829
1897.2981
2019.3175
2155.1875
2307.8810
2473.4042
2639.8093
2795.1591
2940.4530
3070.7253
3183.0031
1I.XR
94896.9444
94660.5827
94405.4666
94129.1056
93829.0101
93503.1915
93149.6620
92768.4321
92359.5127
91920. 4198
91448.6707
90941.7843
90397.2611
89813.1825
69187.5113
88517.7935
87800.5592
87033.3385
86215.1597
65343.5569
84415.5679
83428.2331
82375.1072
8124B.2544
80039.2465
78741.1564
77348.5568
75854.0340
74250.6782
72531.5862
70693.3457
6B735.0379
66647.7854
64416.2511
62025.6085
59469.0018
56751.51 76
53683.7115
50878.1223
47751.2581
IXR
3567693.0239
3472796.0795
3378135.4968
3283730.0303
3189600.9247
3095771.9146
3002268.7230
2909119.0610
2816350.6289
2723991.1162
2632070.6964
2540622.0257
24496B0.2414
2359282.9603
2269469.7778
2180282.2665
2091764.4730
2003963.9138
1916930.5754
1830715.4157
1745371.8587
1660956.2908
1577528.0577
1495152.9505
1413904.6962
1333865.4496
1255124.2933
1177775.7364
1101921 .7024
1027671 .0242
955139.4380
884446.0923
815711.0544
749063.2690
6B4647.017B
622621 .4093
563152 .4075
506400. 6900
452517. I7H5
401639.0562
LXR
37.5504B9
36.639314
35.733158
34.832101
33.937299
33.048745
32.167115
31.292342
30.423676
29.561042
28.705305
27.856320
27.014840
26. 180656
25.354127
24.535001
23.723836
22.920862
22.126007
21.338667
20.559479
19.788046
19.024903
18.271206
17.528018
16.796544
16.077069
15.370066
14.676599
13.996929
13.332117
12.681195
12.044393
11.423838
10.822352
10.242353
9.684629
9.148417
6.633602
8.139777
IXKLXR
6.4411
6.73271
7.0214)
7.30681
7.56B4)
1
7.866 (.|
B.I 36 'M
8. SO/1 |
8.67021
B.927BI
1
9.17921
9. 4238 I
9.66121
9.890 /I
10.1 11 (. 1
1
10.32341
10.5251 I
10.71601
10.69541
11.062/1
1
11.216/1
11.356/1
1 1.48101
11.58801
1 1.67571
11.74231
11.786UI
1 I.B04BI
11.79661
11. 75921
1
11.69091
11.59041
11.4551 1
11.28091
11.06381
1
10.8011 I
10.49191
10.1 3691
9./3bB|
9.29361
1
-------
GENERATED 1 Iff 1.'IUE FOR FEMAlESt UNI IEO S1ATES 1969-71
X TO JUT
TEARS
BO- Bl
61- 82
82- 63
83- 84
84- 65
85- 86
86- 87
87- 88
88- 89
69- 90
90- 91
91- 92
92- 93
93- 94
94- 95
95- 96
96- 97
97- 98
98- 99
99-100
100-101
101-102
102-103
103-104
104-105
105-106
106-107
107-108
108-109
109-110
TQX
0.07095BB866
0.0783256489
0.0861139362
0.0941740430
0.1027508779
0.1127924513
0.1246152479
0.13*8211616
0.1466134576
0.1600259913
0.1726513207
6.1870907321
0.2024356601
0.2174882487
0.2318444843
0.2457565514
0.2584673794
0.2698490298
0.2800120499
0.2890886127
0.2987087410
0.3063929810
0.3146194635
0.3207180105
0.3266656196
0.3309959344
0.3301672669
0.3437093507
0.3571004888
0.3332927650
1XR
0.0001908355
0.0001932289
0.0001955552
0.000197R279
0.0002000200
0.0002020274
0.0002038086
0.0002055091
0.0002072163
0.0002069282
0.0002104634
0.0002117456
0.0002128737
0.0002139670
0.0002151361
0.0002162934
0.0002175554
0.0002189444
0.0002204526
0.0002220688
0.0002235840
0.0002253255
0.0002269690
0.0002288758
0.0002305076
0.0002326978
0.0002357261
0.0002365051
0.0002372619
0.0002434078
TQXR
0.0711497221
0.0785168777
0.0663094913
0.0943718709
0.1029508979
0.1129944787
0.1248190565
0.1370266707
0.1488206741
0.1602349195
0.1728617641
0.1873024777
0.2026485338
0.2177022357
0.2320596204
0.2459728447
0.2586849349
0.2700679742
0.2802325025
0.2693106814
0.2989323250
0.3066183065
0.3148464325
0.3209468863
0.3288963274
0.3312288322
0.3304029930
0.3439456558
0.3573377507
0.3335361728
LXR
'
46159.7565
42675.5027
39506.9663
36096.9675
32692.2404
29326.5449
26012. 8073
22765.9132
19646.3759
16722.5690
14043.0463
11615.5403
9439.9208
7526.9347
5888.3042
,,
4521.8665
3409.6102
2527.5954
1844.9728
1327.9515
943.7609
661.6403
458.7693
314.3274
213.4450
143.2437
95.7973
64.1456
42.0630
27.0451
DXR
3284.2539
3366.5364
3409.9988
3406.7271
3365.6955
3313.7377
3246.6941
3119.53*3
2923.7669
2679.5427
2427.5060
2175.6195
1912.9861
1638.6305
1366.4376
1112.2564
862.0148
682.6226
5 1 7 .02 1 4
384.1905
282.1206
202.8710
144.4419
100.8824
70.2013
47.4464
31.6517
22.0626
15.0378
9.0205
TLXR
44517.6296
41192.2345
37803.9669
34395.6040
31009.3927
27669.6761
24389.3602
21206.1446
18184.4825
15382.8177
12829.2933
10527.7305
6483.4277
6707.6194
5205.0854
3965.7384
2968.6028
2186.2841
1586.4621
1135.6562
602.7006
560.2048
386.5483
263.8862
178.3444
119.5205
79.9714
53.1143
34.5640
22.5349
TXR
353887.7981
309370.1685
268177.9340
230373.9670
195978.3630
164968.9703
137299.2942
112909.9340
91703.7694
73519.3069
58136.4893
45307.1960
34779.4655
26296.0377
19588.4183
14383.3329
10417.5946
7448.9918
5262.7077
3676.2455
2540.3893
1737.6687
1177.4840
790.9356
527.0494
348.7051
229.1846
149.2132
96.0989
61.5349
tXR
7.666587
7.215546
6.787774
6.381733
5.994645
5.625244
5.278142
4.959605
4.667720
4.396407
4.139877
3.900567
3.684296
3.493592
3.326665
3.180840
3.055362
2.947067
2.852458
2.768356
2.691772
2.626335
2.566615
2.516280
2.469252
2.434348
2.392392
2.326165
2.283559
2.275266
1XRLXR
8.80891
6.28481
7.72621
7.14141
6.53911
1
5.92481
5.30161
4.67861
4.07101
3.49381
1
2.95551
2.45951
2.00951
1.61071
1.26681
1
0.97801
0.74181
0.5534)
0.40671
0.29491
1
0.21101
0.14911
0.10411
0.07191
0.04921
1
0.03341
0.0226)
0.01521
o.oiool
0.00661
1
-------
ACE DISTRIBUTION OF RADIATION DEATHS BY STAGE FOR ALL CANCERS COMBINED
ACES
0- 1
1- 2
2- 3
3- 4
4- 5
5- 6
6- 7
7- 8
8- 9
9- 10
10- 11
11- 12
12- 13
13-1*
14- 15
15- 16
16- 17
17- IB
IB- 19
19- 20
20- 21
21- 22
22- 23
23- 24
24- 25
25- 2t
26- 27
27- 28
2B- 29
29- 30
30- 31
31- 32
32- 33
33- 34
34- 35
35- 36
36- 37
37- 3B
3H- 39
39- 40
FETAL
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
o.o .
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
CHILD
0.0
0.0
0.05
0.15
0.24
0.34
0.44
0.54
0.64
0.73
0.83
0.93
0.98
0.98
0.98
.00
.05
.10
.14
.19
.24
.29
.34
.38
.43
.45
.45
.40
.30
.21
.11
.01
0.91
0.82
0.72
0.62
0.53
O.'iH
0.4R
0.4B
ADULT
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
•*.02
0.07
0.12
0.17
0.22
0.21
0.32
0.37
0.41
0.46
0.51
0.56
0.61
0.81
1.17
1.54
1.90
2.26
2.62
2.97
3.33
3.69
4.04
4.40
4.75
5.07
5.37
5.67
TOTAL
0.0
0.0
0.05
0.15
0.24
0.34
0.44
0.54
0.64
0.73
0.83
0.93
.00
.05
.10
.17
.27
.36
.46
.56
.65
.75
.B5
.94
2.04
2.27
2.63
2.94
3.20
3.46
3.73
3.99
4.25
4.51
4.76
5.02
5.27
5.55
5.H5
6.15
-------
ACE DISTRIBUTION 1
ACES
40- 41
41- 42
42- 43
43- 44
44- 45
45- 46
46- 47
47- 48
46- 49
49- 50
50- 51
51- 5?
52- 53
53- 54
54- 55
55- 56
56- 57
57- 5«
58- 59
59- 60
60- 61
61- 62
6?- 63
63- 64
64- 65
65- 66
66- 67
67- 66
66- 69
69- 70
70- 71
71- 72
72- 73
73- 74
74- 75
75- 76
76- 77
77- 7fl
76- 79
79- 80
IF RADIATION
FETAL
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
DEATHS BY
CHILD
0.47
0.47
0.47
0.47
0.47
0.47
0.47
0.46
0.46
0.46
0.46
0.45
0.45
0.45
0.45
0.44
0.44
0.44
0.43
0.43
0.42
0.42
0.41
0.41
0.40
0.39
0.39
0.36
0.37
0.36
0.35
0.34
0.33
0.32
0.31
0.30
0.26
0.27
0.25
0 ?4
SI ACE FOR ALI
ADULT
5.97
6.26
6.55
6.84
7.12
7.40
7.67
7.94
.8.21
«- 6.47
8.72
8.97
9.21
9.44
9.67
9.86
10.09
10.26
10.46
10.64
10.79
10.94
11.07
11.16
11.26
11.35
11.40
11.43
11.43
11.40
11.34
11.25
11.12
10.96
10.75
10.50
10.21
9.67
9.48
9.05
L CANCERS COMBINED
TOTAL
6.44
6.73
7.02
7.31
7.59
7.87
6.14
6.41
8.67
6.93
9.18
9.42
9.66
9.69
10.11
10.32
10.53
10.72
10.90
11.06
11.22
11.36
11.46
11.59
11.68
1 1 . 74
.79
.60
.60
.76
.69
.59
.46
.2fl
.06
10.80
10.49
10.14
9. 14
9.29
-------
-J
ID
AGE DISTRIBUTION C
AGES
80- 81
81- 82
82- 83
83- 84
84- 85
85- 8fc
86- 87
87- 8b
88- 89
89- 90
90- 91
91- 92
92- 93
93- 94
94- 95
95- 96
96- 97
97- 98
98- 99
99-100
100-101
101-102
102-103
103-104
104-105
105-106
106-107
107-10R
108-109
109-110
IF RADIATION
FETAL
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
•-1
DEATHS BY
CHILD
0.22
0.21
0.19
0.17
0.16
0.14
0.12
0.11
^ 0.09
0.08
0.06
0.05
0.04
0.03
0.03
0.02
0.01
0.01
0.01
0.01
0.00
0.00
0.00
0.00
0.00
0.00
0.00
0.00
0.00
0.00
STAGE FOR ALI
ADULT
8.59
8.08
7.54
6.97
6.38
5.79
5.18
4.57
3.98
3.42
2. 89
2.41
1.97
1.58
1.24
0.96
0.73
0.54
0.40
0.29
0.21
0.15
0.10
0.07
0.05
0.03
0.02
0.01
0.01
0.01
L CANCERS COMBINED
TOTAL
8.B1
8.28
7.73
7.14
6.54
5.92
5.30
4.68
4.07
3.49
2.96
2.46
2.01
1.61
1.27
0.98
0.74
0.55
0.41
0.29
0.21
0.15
0.10
0.07
0.05
0.03
0.02
0.02
0.01
0.01
-------
ACE DISTRIBUTION OF RADIATION DEATHS BY CANCER 1TPE FOR ALL STAGES COMBINED
ACES
0- 1
I- 2
2- 3
3- 4
-------
ACE DIS1RIBU1ION OF RADIATION DEATHS bY tANCIR 1YPE FOR ALL S1AOES COMBINED
ACES
40- 41
41- 42
42- 43
43- 44
44- 45
45- 46
46- 47
47- 46
48- 49
49- 50
50- 51
51- 52
52- 53
53- 5*
5*- 55
55- 56
56- 57
57- 58
58- 59
59- 60
60- 61
61- 6?
62- 63
63- 64
64- 65
65- 66
66- 67
67- 68
68- 69
69- 70
70- 71
71- 72
72- 73
73- 74
74- 75
75- 76
76- 77
77- 7B
78- 79
79- 80
LEUKEMIA
.19
.18
.18
.18
.17
.17
.16
.16
.15
.15
.14
.14
.13
.12
.11
.11
.10
.09
.08
.07
.06
.04
.03
.02
.00
0.98
0.97
0.95
0.93
0.91
0.88
0.86
0.83
0.81
0.78
0.74
0.71
0.67
0.64
0.60
BREAST
2.21
2.34
2.48
2.61
2.74
2. 8B
3.00
3.13
3.26
3.36
3.50
3.61
3.73
3.84
3.95
4.05
4.15
4.24
4.33
4.42
4.50
4.57
4.63
4.69
4.74
4.78
4.81
4.64
4.84
4.84
4.82
4.79
4.75
4.69
4.61
4.50
4.36
4.?4
4.08
3.90
LUNC
0.96
.02
.07
.13
.19
.25
.30
.36
.41
.46
.52
.57
.62
.66
.71
.75
.60
.84
.88
.91
.95
.98
2.01
2.03
2.06
2.07
2.09
2.10
2.10
2.10
2.09
2.08
2.06
2.03
2.00
.95
.90
.64
.77
.69
Gl H/S10H.
0.74
0.78
0.83
0.87
0.91
0.96
• •
.00
.04
.09
.13
-11
.20
.24
.28
.32
.35
.38
.41
.44
.47
.50
.52
.54
.56
.58
.59
.60
.61
.61
.61
.61
.60
.58
.56
.54
.50
.46
.41
.36
.30
BONE
0.15
0.16
0.17
0.17
0.18
0.19
0.20
0.21
0.22
0.23
0.23
0.24
0.25
0.26
0.26
0.27
0.28
0.28
0.29
0.29
0.30
0.30
0.31
0.31
0.32
0.32
0.32
0.32
0.32
0.32
0.32
0.32
0.32
0.31
0.31
0.30
0.29
0.28
0.27
0.26
ALL OTHERS
.21
.25
.30
.34
.38
.43
.47
.51
.55
.59
.62
.66
.69
.73
.76
.79
.82
.85
.88
.90
.92
.94
.96
.97
.98
.99
.99
.99
.99
.98
.96
.94
.92
.68
.85
.80
.75
.68
.62
.54
.
TOTA1
6.44
6.73
7.0?
7.31
7.59
7.87
6.14
8.41
6.67
8.93
9.18
9.42
9.66
9.89
10.11
10.32
10.53
10.72
10.90
11 .Ob
11.22
11.36
11.48
11 .59
11. 68
11.74
11.79
II .HO
11.80
11.76
11.69
11 .59
II .46
11.28
11.06
IU.80
10.49
10.14
9.74
9.?9
-------
ACE DISTRIBUTION OF RADIATION DEATHS 6V CANCER TYPE FOR ALL STAGES COMBINED
ACES
80- 81
81- 8?
82- 83
83- 84
84- 85
85- 86
66- 87
87- 8B
88- 89
89- 90
90- 91
91- 9?
93- 93
93- 94
94- 95
95- 96
96-97
97- 98
98- 99
99-100
100-101
101-10?
102-103
103-10*.
10
-------
Sample Problem 6.
All of the previous problems have dealt, with whole body exposure.
This problem examines a partial body exposure situation: dose to the
liver from lifetime inhalation of CM-2U2. This radionuclide is absorbed
and partially retained by the body. The continuous exposure results in
accumulation of the radionuclide and an increasing annual dose. The
cohort's 110 year "life" is divided into nine exposure intervals, each
using an annual dose taken from internal dosimetry calculations.
Twelve cases are analyzed which show the effect of the absolute and
relative risk models using 15 and 30-year latent periods, and 0.2x, 1x,
and lOx radiosensitivity factors for child stage doses.
Input Data:
TOTAL rol'U'.ATlO;! LIV
312141V 1 10
2 :J 12 17
.'J0059G
22 1
22 1
22 1
22 1
22 1
12 1
.000060
LIVLM
LIVE. I
LIVIM
Liv-::>
LIVE-
\I\"1Z
TOTAL P)?UL\TI'.)'i LTV
3131419
t ;;
.000596
21 1
00000155')
00000'* .142
000063339
22 1
22 1
22 1
22 1
12 1
*** r*:v
1 1")
12 17
.000660
LIVI'-l
000000244
000009-43
000071373
I. IV" *
LIVU:I
Livr.r.
LIV.1.
LIVU ''.
1 ')" n IJ-I
U:>. FATAL IT
0 0
22 i*>
.0'X)7Ci
.0004
• —
T
• *.
T
• •»
.2
.2 t
.2
EL \TIvT. RI"K
60
.000532
11
000001606 OOH002161
00006J
110
110
110
110
110
4
•
•
•
•
•
42 000066922
11
11
11
11
11
83
-------
TOTAL POPULATION LIVER FATALITHS FROM LIFETIME CH-242 INHALATION! ABSOLUTE RISK
NUMDtR OF
RAD1 AT ION
ADDI
DCSt RATES! NINE
RISK MODEL! ABSOLUTE
TICNAL RISK! KCNE
*** INPUT DATA
DOSE
CHILI)
ADULT
CUTPU
CANCER
LIVLR
O.OC02 75000
0.000464000
O.COC532000
O.CCC596000
O.OOC660000
0.000766000
0.000*46000
0.000911000
0.001000000
ACE INTERVAL •
ACE INTERVAL <=
POPULATION AT RISK: CENLRAL
(•EfERLNCE TABLE INPUT SOURCE! DISK
ADDITIONAL ANALYSIS! STAGES C CANCERS
ADDITIONAL OUTPUT! NONE
44*
ACE INTERVAL
0 - 2
2 - 8
6-12
12 - 17
17 - 22
22 - 35
35 - 45
45 - 60
60-110
0-10
10 - 110
T DATA BASED OK ACE INTERV/L « 0-110
LATENCY
0
CANCLR
L IVER
TOTAL
TOTAL NUMBER
*** OUTPUT DATA •**
-
*•"
NUMBER OF PREMATURE DEATHS « 0.99772
DECREASE IN POPULATION LIFE EXPECTANCY • 0.00007
TOTAL YEARS OF LIFE LOST TO PREMATURE DEATHS - 7.19927
AVLKACL YEARS OF LIFE LOST PER PREMATURE DEATH • 18.10124
FETAL CHILD ADULT
PLATLAU DEATH RATE LATENCY PLATEAU DEATH RATE LATENCY PLATEAU DEATH RATE
0 0.0 15 110 C.840 15 110 4.200
FETAL CHILD ADULT TOTAL
0.0 0.01877 0.37895 0.39772
0.0 0.01877 0.37895 0.3.'CRE MENTAL DEATHS 0.39772
-------
TOTAL POPULATION LIVER FATALITIES FROM LIFETIME CM-242 INHALATION* ABSOLUTE RISK
NUMBER OF
RADI AT ION
ACOIT
DOSE RATES* NIKE
RISK MODEL* ABSOLUTE
IONAL KISK* NCNE
*** UPUT DATA
DOSE
0
0
0
0
0
0
0
0
0
CHILD
ADULT
CUTPUT
CANCER
LlVtK
.OC0275000
.000464000
.CC0532000
.C00596000
.000660000
.000766000
.COOB48000
.OOC911000
.001000000
AGE INTERVAL -
AGE INTERVAL -
POPULATION AT RISK* GENERAL
REFERENCE TABLE INPUT SOURCE* DISK
ADDITIONAL ANALYSIS* STAGES C CANCERS
ADDITIONAL OUTPUT* NONE
«**
AGE INTERVAL
0 - 1
2 - B
8 - 12
12 - 17
17 - 22
22 - 35
35 - 45
45 - 60
60 - 110
0 - 10
10 - 110
DATA EtASED OK AGE INTERVAL ' 0-110
LATENCY
0
CANCER
L IVEK
TOTAL
TOTAL NUMBER
**• OUlpUT DATA •**
«T
NUMhER OF PREMATURE DEATHS « 0.20029
(HCkLASE IN POPULATION LIFE EXPECTANCY • 0.00003
TdTil YEAkS OF LIFE LOST TO PREMATURE DEATHS «= 2.B1565
AVERAGE YEARS OF LIFE LOST PER PREMATURE DEATH - !<.. 05774
FETAL CHILD ADULT
PLATEAU DEATH RATE LATENCY PLA1EAU DEATH RATE LATENCY PLATEAU UEA1H KATE
0 0.0 30 110 0.840 30 110 4.200
FETAL CHILD ADULT TOTAL
0.0 0.0134t 0.1B682 0.20029
0.0 0.0134fc 0.186B2 0.20029
OF INCREMENTAL OfATHS 0.20C29
-------
TCTAL POPULATION I IVEk FATALITHS FROM LIFETIME CM-242 INHALATION:
NUMBER OF
RADIATION
ADO IT
OOSE RATES! NINE
RISK MODfLi ABSOLUTE
IONAL RISKt NINE
«** INPUT DATA
DOSE
0
0
0
0
0
0
0
0
0
CHILD
ADULT
OUTPUT
CANCER
LIVEF
.000275000
.000464000
.CC.C532000
.OC0596000
.OC0660000
.000766000
.CCOP40000
.000911000
.001000000
AGE INTERVAL •
AGE INTERVAL *
POPULATION AT R 1 SK I GENERAL
KfEKNCE TAPLE
ABSOLUTE RISK
INPUT SOURCE i DISK
ADDITIONAL ANALYSIS! STAGES t CANCERS
ADD!
***
AGE INTERVAL
0 - 2
2 - C
e - 12
12 - 17
17 - 12
22 - 35
35 - 45
45 - 60
to - no
0-10
10 - 110
DATA BASED OK AGE INTERV/l - 0-110
LATENCY
0
CANCER
L IVEK
TOTAL
TOTAL NUMBER
**«
«r
NUMBER OF PREMATURE DEA
DECREASE IN f'CPULAT ION
TIONAL OUTPUTl NONE
OUTPUT DATA ***
THS * 0.47280
LIFE EXPECTANCY • 0.00009
TOTAL YIAkS OF LIFL LOST TO PREMATURE DEATHS « 9.33692
AVERAGE YEARS OF LIFE LOST PER PREMATURE DEATH « 19.74791
FETAL CHILD
PLATEAU DEATH RATE LATENCY PLATIAU UIATH RATE
0 0.0 15 110 4.200
FETAL CHILD ADULT
0.0 0.09385 0.378S5
0.0 0.09385 0.37695
OF INCREMENTAL DEATHS
ACULT
LATENCY PLATEAU DEATH RATE
15 110 4.200
TOTAL
0.47281
0.47281
0.47280
-------
TOTAL POPULATION LIVER FATALITIES FRUM LIFETIK CM-242 INFLATIONS ABSOLUTE RISK
NUMBER OF
RAD1 AT ION
AI'DIT
DOSE RATES: NINE
RISK MODEL' AtSOlUTl
1DNAL RISK! KCNE
*** INPUT DATA
DOSE
0
0
0
0
0
0
0
0
0
CHILD
ADULT
OUTPUT
CANCER
LIVER
.000275000
.C00464000
.000532000
.OC0596000
.000660000
.000766000
.C00848000
.000911000
.00 1000000
AGE INTERVAL «
AGE INTERVAL •
POPULATION AT K I SK : GENERAL
REFERENCE TABLE INPUT SOURCE t UISK
ADDITIONAL ANALYSIS' STAGES t CANCERS
ADDITIONAL OUTPUT! NONt.
«*«
AGE INTERVAL
0 - t
2 - 8
t - 12
12 - 17
17 - 22
22 - 35
35 - 45
45 - 60
60 - 110
0-10
10 - 110
DATA BASED ON AGE INTERVAL * 0-110
LATENCY
0
CANCER
LIVER
TOTAL
TOTAL NUMBER
*** OUTPUT DATA •**
'
«r-
NUHBLR OF PREMATURE DEATHS ° 0.25419
DECREASE IN POPULATION LIFE EXPECTANCY - 0.00004
TOTAL YEARS OF LIFE LOST TD PREMATURE DEATHS • 3.96654
AVERAGE YEiRS OF LIFE LOST PER PREMATUkE DEATH « 15.66306
FETAL CHILD ADULT
PLATEAU DEATH RATE LATENCY PLATEAU DEATH RATE LATENCY PLATEAU DEATH KATE
0 0.0 30 HC 4.200 30 110 4.200
FETAL CHILD ADULT TOTAL
0.0 0.06738 0.18682 0.25420
0.0 0.06738 0.18662 0.25420
OF INCREMENTAL DEATHS 0.25419
-------
TOTAL f-OPULATlOK LIVIK
NUMBER OF DCSE RATES* NINE
RADIATION RISK HODLLi ABSOLUTE
ADDITIONAL R1SM KCNE
*«* INPUT DAtA ««*
DOSE AGE
O.C00275000 0
O.C00464000 2
O.OC0532000 8
0.000596000 I!
O.C00660000 . 17
O.C00766000 22
0.000(148000 35
O.C00911000 45
O.OC1000000 60
CHILD ACE INTERVAL = 0
ADULT Act INTERVAL « 10
OUTPUT DATA BASED OK ACE INTERVAL « 0
CANCER FETAL
FATALITIES FROM LIFETIH CM -24 2 INKALAIlONi ABSOLUTE RISK
POPULATION AT HSK: GENERAL
REIEkENCE TABLE INPUI SOURCE « DISK
ADDITIONAL ANALYSIS* STAGES t CANCERS
ADDITIONAL OUTPUT i NONE
*** OUTPUT DATA *»«
INTERVAL
2
e
- 12
- 17
- 22 ^
- 35
-
-------
TOTAL FUPULATION LIVEK FATALITIES FkOM LIFETIME CM-242 INHALATION! ABSOLUTE RISK
NUMBER OF
RADI AT ION
AUDIT
DOSE RATE Si NINE
RISK MODEL: APSOLUTE
IONAL RISK! NCNE
»** INPUT DATA
DOSE
0
0
0
0
C
C
0
0
0
CHILD
ADULT
CUTPUT
CAF.CIR
LIVLk
.OGC275000
.000464000
.000532000
.OC0596000
.C00660000
.OC07660CO
.CC0848000
.cocsnooo
.001000000
ACE INTERVAL =
ACE INTERVAL '
PDPULATILN AT RISK: tlNEKAL
REFERENCE TABLE INPUT SuUKCEl U1SK
ADDITIONAL ANALYSIS! STAGES t CMJtERS
ADDITIONAL OUTPUT » NONE
*««
ACE INTERVAL
C - 2
2 - e
B - 12
12 - 17
17 - 22
2i - 35
35 - 45
45 - 60
60-110
0-10
10 - 110
DATA BASED ON ACE INTERVAL • 0-110
LATENCY
0
CANCER
LIVER
TOTAL
TOTAL NUMBER
**+ OUIPUT DATA ***
*-""
NUMBER (JF F'kEHATURE DEATHS « 0.86059
OlCKLAil IN PEPULATION LIFE EXPECTANCY « 0.00017
TOTAL YEARS OF LIFE LOST TO PREMATURE DEATHS « 17.15B94
AVLkACl YEARS OF LIFE LOST PER PREMATURE DEATH « 19.93851
FITAL CHILD ADULT
PLATEAU DEATH RATE LATENCY PLATEAU DEATH RATE LATENCY PLATEAU DEATH KATE
0 0.0 30 110 42.000 30 110 4.200
FETAL CHILD ADULT TOTAL
0.0 0.6737fc 0.1066? 0.86059
0.0 0.6737fc 0.18682 0.06059
OF INCREMENTAL DEATHS 0.86059
OTAL POPULATION LIVIR FATALITIES FkUM LIFETIME CH-242 INHALATIONt RELATIVE MSK
-------
MJMOER OF
RADI AT ION
ADDI T
TOTAL POPULATION LIVER FATALITIES FROM LIFETIME CM-Z42 INHALATION: RELATIVE RISK
POPULATION AT RISK: GENERAL
OOSf RATlSt NIKE REFERENCE TAPLE INPUT SOURCE* DISK
RISK MODEL: RELATIVE ADDITIONAL ANALYSIS' STAGES i CANCERS
IONAL RISK: NONE ADDITIONAL OUTPUT t NONE
*** 1KPUT DATA ««*
DOSE AGE INTERVAL
0
0
0
0
0
0
0
0
0
CHILO
ADULT
CUTPUT
CAKCIK
LIVL^
.OC0275000 0 - 2
.OOC464000 2 - fc
.CCC532000 B - 12
.000596000 12 - 17
.000660000 17 - 22
.000766000 22 - 35
.00064HOOO 35 - 45
.OC09110CO 45 - 60
.001000000 60 - 110
AGl INTERVAL « 0-10
ACE INTERVAL = 10 - 110
DATA BASED OK AGE INTERVAL « 0-110
*«* OUTPUT DATA •**
4-
NUMBER OF PREHATURE DEATHS • 0.40528
DECREASE IN PCPULATION LIFE EXPECTANCY • 0.00005
TOTAL YEARS OF LIFE LOST TC PREHATURE DEATHS • 4.83513
AVERAGE YEARS OF LIFE loSl PER PREMAIUhE DEATH • 11.93045
MTAL CHILD ADULT
LATENCY PLATEAU UEATHRATE LATENCY PLATEAU DEATH RATE LATENCY PLAIEAU DEATH KATE
0 0 0.0 15 lie C.022 15 110 0.110
CANILK F( TAl CHILU ADULT TOTAL
LIVI.k 0.0 0.01050 0.3947B 0.40526
ICTfL 0.0 0.01050 0.3947H 0.40528
TLT/lL NijMHEK (IF INCREMENTAL LLAThS 0.4052B
-------
NUMBER UF
RAO 1 41 ION
ADD1 T
TOTAL
DOSE RATI S: N IM
RISK MODI L> RtLA
ICNAL RISK: NOM
FOF-ULA1IOK LIVER FATALITIES (ROM L 1 F L 1 1 hi CM-i'42 INhALAIIUI': REl/ilVE RISK
PUPULAIILN Al RISK: tlMKAL
REKRLNCE TAPLl IMLT SOURCE « U 1 SK
TIVC ADDITIONAL ANALYSIS: STAGES L CANCEKS
ADD! 1ICNAL OUIPUH NONE
«*» INPUT DATA ««*
DOSE
0
0
o
0
0
0
0
b
0
CHILD
ADULT
OUTPUT
CANCER
.OC0275000
.000464000
.CCC532000
.000^96000
.COC660000
.OCC766000
.OOCP40000
.CC091 1000
.001000000
ACL INTERVAL -
ACE INTERVAL «
DATA BASED OK A
AGE INTERVAL
0 - 2
2 - e
t - \2
li1 - 17
1 7 - 22
22 - J!:
3t - 4^>
4b - 60
60 - 110
0 - 1C
10 - 110
Gl INTERVtl = 0-110
*** OUTPUT DATA «**
NUMbER OF fkl MATURE DEAIHS = 0.25103
OIL HA SI IK PCPULAIION LIFE EXPECTANCY ' 0.00003
TOTAL YEARS OF LIFE LOST 10 PREMATURE DEAIHS « 2.74694
AVERAGE YEARS DF LIFE LOST PLK PRLMATUnt DEATH « 10.94261
MTAL CHILD ADULT
LATENCY PLATEAU DEATH KATE LATENCY PLAIIAU DlAIHKATE LATENCY PLATIAU DEATH KATE
LIVER
CANCEK
LIVER
TGTAL
TOTAL
0 0 0.0 30 IK 0.022 30 110 0.110
FETAL CHILD ADULT TOTAL
0.0 0.01033 0.24070 0.25103
0.0 0.01033 0.24070 0.25103
NUMBER OF INCREMENTAL DEATHS o. 25103
-------
TOTAL POPULATE LIVER FA1ALIIMS FROM LIHUHt CM-242 INHALATIONi RELATIVE. RISK
NUMBER OF DOSE RATES* NINE
RADIATION RISK MOOfcLt RELATIVE
ADDITIONAL RISK: NCNE
*»* INPUT DATA
DOSE
0.000275000
0.000464000
0.000532000
O.C00596000
0.000660000
0.000766000
0.000646000
0.000911000
0.001000000
CHILD ACE INTERVAL •
ADULT ACE INTERVAL *
POPULATION AT RISK: CLNERAL
REFERENCE TABLE INPUT SOURCE! DISK
ADDITIONAL ANALYSIS* STAGES t CANCERS
ADDITIONAL UUTPUIt NONE
«**
ACE INTERVAL
0 - 2
2 - 6
b - 12
12 - 17
17 - 22
22 - 35
35 - 45
45 - 60
60-110
0-10
10 - 110
OUTPUT DATA BASED OK ACE INTERVAL * 0-110
CANCIK
LATENCY
LIVEk 0
CANCER
LIVER
TCTAL
TOTAL NUMBER
«** OUTPUT DATA *•*
*r
NUMELR OF PREMATURE DEATHS • 0.4472B
OUKEASE IN PEPULATION LIFE EXPECTANCY - 0.00005
TOTAL YEARS OF LIFE LOST TO PREMATURE. DEATHS « 5.44420
AVLRAGE YEARS OF LIFE LoST PER PREMATURE DEATH < 12.17162
FETAL CHILD ADULT
PLATEAU DEATH RATE LATENCY PLATEAU OiAIH RATF LATENCY PLATEAU DEATH KATE
0 0.0 15 110 0.110 15 110 0.110
FETAL CHILD ADULT TOTAL
0.0 0.05250 0.3947H 0.44728
0.0 0.05250 0.3V47P 0.4472B
OF INCREMENTAL DEATHS 0.44728
-------
NUMBER Oh
RAD I AT 1UN
AC.01 T
TOTAL IliPULATIOK LIVER FATALITIIS 1 RUM 1 I F I ! I Ml CM-2<.2 INHALATION: RELATIVE RISK
PEiPUEATlUN AT k 1 SK : CENLKAL
DOSE RATES: MM REFERENCE TABLE IKPU SOURCE « DISK
RISK MCIULL : RELATIVE ADDITIONAL ANALYSIS: STACES C CANCERS
IONAL RISK: NTM ADDITIONAL OUTPUT: NOKE
*** IKPUT DATA *««
DOSE ACL INTERVAL
U
0
c
0
0
0
0
0
0
CHILD
AOllLT
OUTPUT
CANCER
LIVER
.CC0275000 0 - 2
.000
-------
TOTAL POPULATION LIVER FATALITIES FROM LIFETIME CM -24 2 INHALATION: RELATIVE RISK
1
NUMBER OF
RADI AT ION
ADD IT
DCSE RATES: NINE
RISK MODEL: RELAT |V[
IONAL RISK: NCNE
*** INPUT DATA *«*
OOSE AGE INTE
0
0
0
0
c
0
0
0
0
CHILD
ADULT
OUTPUT
CANCIR
LI VER
.000275000 0 -
. 000464000 2 -
.OC0532000 8 -
.000596000 12 -
.OC0660000 17 -
.OC0766000 22 -
.00084BOOO 35 -
.OC09HOOO 45 -
.OC1000000 60 - 1
AGE INTERVAL • 0 -
ACE INTERVAL * 10-1
DATA BASED UK AGE INTERVAL « 0-1
FETAL
LATENCY PLATEAU DEATH
0 0 0.0
CANCER
LIVER
TCTAL
TOTAL NUHbEK OF INCREMENTAL
POPULATION AT RISK: GENERAL
REFERENCE TABLE INPUT SOURCE i DISK
ADD II IONAL ANALYSIS! STAGES t CANCERS
ADDITIONAL OUTPUT! NONE
RVAL
2
e
12
17
22
35
45
60
10
10
10
10
*«* OUTPUT DATA •»•
4--
NUMltLR OF PREMATURE DEATHS * 0.91981
DECREASE IN PLPULATION LIFE EXPECTANCY - 0.00012
TOTAL YtARS OF LIFE LOST TO PREMATURE DEATHS • 12.29628
AVERAGE YEARS OF LIFE LOST PER PREMATURE DEATH • 13.36827
CHILD ADULT
RATI LATENCY PLAILAU DEATH RATE LATENCY PLATEAU DEATH RATE
15 110 1.100 15 110 0.110
FETAL CHILD ADULT TOTAL
C.O 0.52504 0.3947B 0.91981
0.0 0.52504 0.39476 0.91981
DEATHS 0.91981
-------
TOTAL POPULATION LIVER FATALITIES FROM LIFETIME CM-2
60
10
10
10
10
»«* OUTpUT DATA *«•
_
NUHbER OF IMMATURE DEATHS * 0.75739
DECREASE IK JLPULATION LIFE EXPECTANCY • 0.00010
TOIAL YEARS Of LIFE LOST TO PREMATURE DtATHS • 9.«
-------
Reference Life Table
Male Population
0.0224500000
0.0013298550
0.0009423820
0.0007689700
0.0006464320
0.0005749780
0.0005444890
0.0005139480
0.0004627920
0.0004115610
0.0003499710
0.0003500930
0.0004120180
0.00058-73680
0.0008454830
0.0011351440
0.0014153770
0.0016760300
0.0018446550
0.0019830350
0.0021118120'j
0.0022622310
0.0023509500
0.0023564900
0.0022675740
0.0021675080
0.0020667690
0.0019865170
0.0019798840
0.0020262460
0.0021047710
0.0021837780
0.0022739650
0.0023968500
0.0025205940
0.0026775060
0.0028895500
0.0031141870
0.0033842420
0.0036895950
0.0040091330
0.0043433430
0.0047368310
0.0051799710
0.0056853580
0.0062325860
0.0068121430
0.0074370510
0.0081209810
0.0088668820
0.0096781690
0.0105939^10
0.0116086040
0.0127526840
0.0140110320
1
X
1 00000. OOOOOOOUUO
97755.0000000000
97625.0000244750
97532.999981 7019
97458.0000307060
97395.0000608301
97339. 00007H4852
97286.0000636714
97236. 0001ie51u7
97191.0000755438
97151.0000503617
97117.0000177231
97083.0000358359
97043.0000923271
96986.0001394489
96904.0001250930
96794.0001307750
96657.0001292519
90495.0000973252
96317.0001129207
96126.0001306018
95923.0000900139
95706.0001055973
95481.0000846490
95256.0000627596
95040.0000336732
94834.0000732802
94638.0001017828
94450.0001057346
94263.0000617253
94072.0000349022
93874.0000173167
93669.0000413069
93456.0000136279
93231.9999999953
92996.9999801873
92747.9999547583
92479.9999714890
92191.9999578178
91879.9999194966
91540.9999311936
91173.9998875164
90777. -9999333230
90347.9998891208
89879.9998697871
89368.9998934874
88811.9999159173
88206.9998723741
87550.9999157662
86839.9999089193
86069.9998768469
85236.9998722088
84333,9998626956
83-354.9998545535
82291.9998815883
T
X
6705203.4960201313
6606325.9060201313
6508635.9960078939
6411056.9960048057
6313561.4959.986019
6216134.9959528339
6118767.9958831763
6021455.4958120983
5924194.4957210072
5826930. 9956239U02
5729U09. 9955610274
5632675.9955269850
5535575.9955002058
5438512.9954361245
5341498.4953202365
5244553.4951879657
5147704.4950600318
5050978.9949300184
4954402.9948167300
4857996.9947116072
4761775. 4945U98461
4665750.9944795384
4569936.4943817330
4474342.9942866100
4373974.4942129059
4283826. 49416468°7
4188889.4941112131
4094153.4940236816
3999609.4939199230
3905252.9938361931
3811085.4937878796
371 7112.4937617702
3623340.9937324584
3529778.4937049912
3436434.4936981 797
3343319.9937080885
3250447.4937406159
3157833.4937774923
3065497.4938128390
2973461.4938741820
2881750.9939488370
2790393.4940394822
2699417.4941290626
2608854.4942178410
2518740.4943383872
2424115.9944567499
2340025.4945520477
2251515.9946579020
2163636.9947638321
2076441.4948514896
1989986.4949586065
1904332.9950840737
1819547.4952166267
1735702.9953580021
1652879.4954899314
-------
Reference Life Table (cont)
tqx
0.0153317150
0.0167594970
0.0182672230
0.01 936483-30
0.0215772140
0.0233916550
0.0253225900
0.0273367530
0.0295391690
0.0320114380
0.034624.S330
0.0374611460
0.0404249480
0.0435055540
0.0466328800
0.0499273370
0.0534366510
0.0574101640
0.0619219490
0.0670434050
0.0726344820
0.0735453180
0.0846378910
0.0906844170
0.0969016130
0.1036475260
0.1112454110
0.1193270540
0.1276595750
0.1366373180
0.1473268530
0.1597791240
0.1727793090
0.1352895950
0.1967599870
0.2083414920
0.2213702700
0.2350698860
0.2500000000
0.2657807310
0.2797388390
0.2910994760
0.3013293940
0.3107822410
0.3190184050
0.3288288290
0.3355704700
0.3434343430
0.3538461540
0.3571428570
0.3703703700
0.3529411770
0.3636363640
0.4285714290
0.2500000000
0.0
Male Population
1
X
81133.9999233034 1
79894.9999010943 1
78555.9998899369 1
T
X
571163.9955874856
490646.9956752670
411421 .4957797716
77120.9999219594 1333582.9958738235
75588.9998960617 1
73957.9998692584 1
72227.9998518266 1
70398.9998250538 1
63470.9998054028
66444.9998205618
64317.9993283959
62090.9998254436
59764.9998156967
5734H. 99981 76772
54853.9993092632
52295.9498186373
49684. 999H1 19408
47029.. 9993170550
44329.9998146379
41584.9993269459
38746.9998416230
'^35978.999854^727
33152.9998805420
30346.9993903296
27594.9998975760
24920.9998967661
22337.9999120200
19352.9999308894
17483.9999360742
15251.9999349349
13167.9999436893
11227.9999516813
9433.9999551246
7303.9999617763
6357.9999694783
5106. 99997?! 381
4042.9999830489
3147.9999351913
2407.9999875444
1805.99999065o3
1325.9999929551
954.9999944122
676.9999964588
472.9999977879
325.9999984324
221.9999989365
143.9999992432
98.9999994705
64.9999996953
41.9999997931
26.9999998730
16.9999999301
10.9999999'457
6.9999999615
3.9999999750
0.0
257227.9959648130
IH2454. 4960821532
109361 .4962216108
03H047. 9963831 683
9f>3612.99'>5679375
901154. 996754')552
835773.4969304763
772563. 9971035566
711640.9972829864
653083.9974662995
596982. 4976528292
543407. 49783887S7
492416.998023539-'.
444059.4932090915
393379.4933932451
355421 .9935724531
315230.9987381687
277842.9988898708
243276.9990221135
211526.9991366777
182555.9992427249
156297.9993455539
132663.4994411608
111572.9995197061
92904.4995862244
76536.4996507199
62326.4997114078
50128.4997637225
39797.4998103170
31178.4993518640
24097.4998862365
18364.9999124280
1 3789.9999318345
10194.4999477144
7416.4999613466
5309.4999722452
3743.4999804385
2602.9999867548
1786.9999913193
121 1.9999941959
812.4999960608
538.4999973514
352.9999982590
22^.9999988996
146.9999993167
93.4999995725
58.9999997394
36.9999998378
22.9999998999
13.°999999463
8.4999999781
5.0
98
-------
Reference Life Table
Female Population
a
t X
0.0174600000
0.0011704360
0. 0007642220
0.0006016480
0. 00051 01 780
0.0004287680
0.0003778860
O.U003473780
0.0003066170
0.0002862630
0.0002556650
0.0002557310
0.0002762600
0.0003172750
0.0004095170
0.0004916220
0.0005340880
0.0006562020
0.0006874120
0.0007084190
0.00071 91 950 'W
0.0007219950
0.0007511060
0.0007722640
0.0007831660
0.0008044060
0.0008360170
0.0008573760
O.U00909KU50
0.0009520260
0.0010254390
0.0010990720
0.0011937010
0.0012732670
0.0014047720
0.00151U9520
0.0016593440
0.0017979970
0.0019687920
0.0021510570
0.0023239430
0.0025190770
0.0027262060
0.0029773570
0.0032413020
0.0035397100
0.0038518740
0.0041567760
0.0044761310
0.0048429560
0.0052257980
0.0056581880
0.0061086350
0.0066002210
O.OU71122800
1
X
100000. 0000000000
98254.0000000000
98138.9999812560
98063. 99999M4123
98004.9999389413
97954.9999940569
97913.0000246194
97H76. 0000726921
97342. 0001 0353K9
97812.0000829931
97784.0001264134
97759.0001600210
97734.0001731460
97707.0001782582
97676.0001897766
97636.0002072069
97588.0002015130
97531.0002216513
97467.0001842438
97400.0001987132
97331 .0001879724
97261.0002192922
97190.0001754371
97117.0001831653
97042.0002201359
96966.0002249915
96888.0001926145
96807.0001773574
96724.0001787734
96636.0001997907
96544.0002150645
96445.0002320280
96339.0002327330
'J6224. 0002713161
96101.0003076607
95966.0003132565
95821.0002931512
95662.0002912407
95490.0003017031
95302.0003530291
95097.0003180557
94876.0003098455
94637.0003596130
94379.0004014106
94098.0004239124
93793.0003869424
93461.0003655427
93101.0003682207
92714.0003643141
92299.0003531494
91852.0003555951
91372.0003558408
90855.0003998914
90300.0003645236
89704.0004058177
T
X
7465024.1789402708
7365397.1789402708
7267700.6789496429
71 69599. 178959S088
7071564.6789661320
6973584.6789746331
6875650.6789652950
6777756.1789166392
6679897.1788285237
6582070.1787352578
6484272.1786305546
6386500.6784773376
6288754.1733007542
6191033.6781250522
6093342.1779410350
5995686.1777425434
5898074.1775381835
5800514.6773266015
5703015.6771236539
5605582.1769321756
5508216.6767388331
5410920.6765352008
5313695.1763378363
5216541.6761585353
5119462.1759568849
5022458.1757343214
4925531.1755255186
4828683.6753405328
4731918.1751624674
4635238.1749731854
4538648.1747657580
4442153.6745422119
4345761.6743093316
4249480.1740575572
4153317.6737673188
4057284.1734573604
3961390.6731541567
3365649.1728619609
3770073.1725654891
3674677.1722381231
3579477.6719025809
3484491 .1715836304
3389734.6712539012
3295226.6708733396
3200983.1704607282
3107042.6700553009
3013415.6696790585
2920134.6693121768
2827227.1689459095
2734720.6685871778
2642645.168232^056
2551033.1678770878
2459919.6674992219
2369342.1671170145
2279340.1667318440
99
-------
Reference Life Table (cont)
Female Population
0.0076796930
0.0082935440
0.0089447680
0.009612617U
0.0103568520
0.0111347330
0.0119965320
0.0129837340
0.0141045780
0.0153811940
0.0167758290
0.0183126810
0.0200452380
0.0219409950
0.0240743250
0.0263220070
0.0287891980
0.0316559370
0.0350280770
0.0389261110
0.0432520010
0.0478927200
0.0529426560
0.0534052070
0.0643257180
0.07096505-W
0.0783332170
0.0361223570
0.0941U33590
0.1027611550
0.1128038460
0.1246279480
0.1368352220
0.1486288570
0.1600427100
0.1726694910
0.18711U5420
0.2024572090
0.2175115210
0.2318694260
0.2457831320
0.2584954980
0.2698785740
0.2300429180
0.2891207150
0.2937421380
0.3064275040
0.3146551720
0.3207547170
0.3287037040
0.3310344830
0.3302061860
0.3437500000
0.3571428570
0.3333333330
0.0
X
89066.0004373114
88382.0004523811
87649.0004428213
86865.0004684283
86030.0004882205
85139.0005056041
84191.0004670873
83181.0004358719
82101.0004523586
80943.0004876003
79698.0004941584
78361.0004662265
76926.0004618476
75384.0004742018
73730.0004967173
71955.0005025092
70061.0004755971
63044.0004608271
65390. 000466C111
63532.0004569296
61107.0004495411
58464.0004049906
55664.0004035145
52717.0003735674
49633.0003420377
46445.0003299519
43149.0003207266
39769.0003152701
36344.0002725853
32921.0002474163
29538.0002382365
26206.0002082145
22940.0001769771
19801. 0001600304 v
16858. 0001 388309 V
14160.0001114320
11715.0000996311
9523.0000814591
7595.0000636601
5943.0000478183
4565.0000380127
3443.0000310898
2553.0000234392
1864.0000176915
1342.0000135851
954.0000101274
669.0000074499
464.0000049910
318.0000036126
216.0000024478
145.0000015792
97.0000010214
64.9700006422
42.6365629214
27.4092190270
0.0
100
X
2189955.1663100296
2101231.1658649335
2013215.6654173324
1925958.6649617078
1839511.1644833835
1753926.6639864712
1669261.6635001258
1585575.6630486462
1502934.6626045310
1421412.6621345517
1341092.1616436725
1262062.6611634803
1184419.1606994432
1108264.1602314187
1033707.1597459592
960864.6592463459
889856.6587572927
820804.1582390806
753837.1578252615
689101.1573633911
626756.6569101558
566971.1564828899
509907.1560786374
455716.6556875964
404539.1553272939
356497.6549912992
311700.6546659600
270241.6543479616
232185.1540540340
197552.6537940332
166323.1535512069
138451.1533279814
113878.1531353856
92507.6529668568
74178.1528174011
58669.1526922697
45731.6525367382
35112.6524961931
26553.6524236335
19784.6523678943
14530.6523249789
10520.6522904276
7528.6522631631
5320.1522425977
3717.1522269594
2569.1522151032
1757.6522063146
1191.1522000941
800.1521957923
533.1521927621
352.6521907485
231 .6521894432
150.6671836164
96.8639068346
61 .8410153604
39.0
-------
Reference Life Table
Total Population
t X
0.0200200000
0.0012449230
0.0008582290
0.0006953530
0.0005730420
0.0005017000
0,0004712200
0.0004304470
0.0003793670
0.0003487390
0.0003078190
0.0002976500
0.0003490720
0.0004621690
0.0006267S50
0.000822529U
0.0010084280
0.0011639520
0.00127S7460
O.U013423370
0.0014061790 'j
0.0014702H4!)
0.0015139260
0.0015266070
0.0015081390
0.00146H7500
0.0014396140
0.0014103490
0.0014437260
0.0014772440
0.0015633690
O.OU16238700
0.0017157350
0.0018346690
0.0019436760
0.0020850530
0.0022485020
0.0024449100
0.0026640240
0.0028955160
0.0031503820
0.0033968270
0.0037104150
0.0040381950
0.0044350240
0.0048369310
0.0052883350
.0.0057355890
0.0062457010
0.0067761420
0.0073843460
0.0080394040
0.0037552080
0.0095695430
0.0104293840
X
100000.0000000000
97998.0000000000
97876.0000358460
97792.0000142112
97724.0000536253
97668.0000971866
97619.0000615378
97573.0000363288
97531.0000311822
97493.9999882933
97460.0000282314
97429.9999884827
97400.9999489862
97366.9999871319
97321.9999781149
97261.0000083586
97181 .0000152827
97082.9999737993
46970. OOOU218138
96846.0000221659
i 96716.0000530341
96580.0000447955
96438.0000160097
96292.0000203974
96144.9999791223
95999.9999549988
95858. 99<)955064fi
95720.9999967035
95585.9999800792
95447.9999866719
95307.0000013796
95157.9999920945
95002.9999806473
94840.0000084755
94666.0000005000
94481. 9999682o30
94284.9999908031
94072.9999797538
93842.9999613733
93592.9999572442
93321.9999283800
93027.9999796016
92711.9999575149
92367.9999621925
91994.9999665852
91586.9999338533
91143.9999346763
90661.9999297817
90141.9999602665
89578.9999809726
88971.9999568835
88314.9999248899
87604.9999612337
86837.9999647331
86006.9999900366
X
7075647.4998189092
6976648.4998189092
6878711.4998009864
6780877.4997759578
6683119.4997420397
6585423.4996666338
6487779.9995872716
6390183.9995383383
6292631.9995045830
6195119.4994948453
6097642.4994865831
6000197.4994782261
5902781.9995094917
5805397.9995414328
5708053.4995588094
5610761.9995655727
5513540.9995537521
5416408.9995592113
5319382.4995614048
5222474.4995394151
5125693.4995018153
5029045.4994529006
4932536.4994224980
4836171.4994042946
4739952.9994045349
4643830.4994374744
4547950.9994824426
4452160.9995065585
4356507.4995181672
4260990.4995347918
4165612.9995407662
4070380.4995440294
3975299.9995576586
381J0378. 4995630973
3785625.4995586097
3691051.4995742184
3596667.9995946754
3502488.9996093970
3408530.9996388336
33-14812.9996795249
3221355.4997367130
3128180.4997827224
3035310.4998141644
2942770.4998543109
2850588.9998899221
2758797.9999397029
2667432.5000054382
2576529.5000732094
2486127.5001231854
2396267.0001575660
2306991.5001886380
2218348.0002477514
2130388.0003046896
2043166.5003417062
1956744.0003643215
101
-------
Reference Life Table (cont)
0.0113735170
0.0123481730
0.0134170850
0.0145143190
0.0157058340
0.0169497920
0.0182908890
0.0197391560
0.0213328730
0.0230609390
0.0249398750
0.0269892640
0.0291885240
0.0315150780
0.0340055480
0.0366062210
0.0394373270
0.0426603900
0.0464370910
0.0507610340
0.0555074940
0.0606015420
0.0659622230'
0.0715430180
0.0773957380
0.0839450190
0.0912044050
0.0989276600
0.1069553060
0.1154920040
0.1255978570
0.1374576090
0.1497875580
0.1616319830
0.1728647690
0.1850059160
0.1988913820
0.2136738060
0.2285774150
0.2433460080
0.2577171570
0.2693423600
0.2806088680
0.2897884080
0.2979274610
0.3081180810
0.3146666670
0.3190661480
0.3314285710
0.3333333330
0.3333333330
0.3461538460
0.3529411760
0.3636363640
0.3571428570
0.0
Total Population
1
X
85109.9999604525
84141. 9999290323
83102.9999573426
81987.9999431600
80797.9999578130
79528.9999829435
78180.9999752646
76750.9999828080
75236.0000209914
73630.9999875156
71932.9999882945
70138.9999602114
68245.9999735893
66253.9999654562
64165.9999887328
61983.9999961480
59714.9999938250
57360.0000122635
54913.0000413403
52363.0000613376
49705.0000348820
46946.0000436758
44101.0000502970
41192.0000504563
38245.0000493905
35285.0000457579
32323.0000465017
29375.0000594456
26469.0000410648
23638.0000421587
20908.0000467377
18282.0000467115
15769.0000325527
13407.0000255747
11240.0000253600
9297.0000174161
7577.0000131421
6070.0000091142
4773.0000047467
3682.0000018667
2785.9999999565
2068.0000005657
1510.9999999333
1087.0000004040
772.0000007910
542.0000006633
375.0000005569
257.0000002567
175.0000001388
117.0000001678
78.0000001509
52.0000001266
34.0000000908
22.0000000747
14.0000000396
0.0
T
X
1871185.5003890770
1786559.5004443347
1702937.0005011472
1620391.5005508962
1538998.5006004099
1458835.0006300318
1379980.0006509279
1302514.0006718917
1226520.5006699921
1152087.0006657337
1079305.0006778338
1008269.0007035810
939076.5007366807
871826.5007671580
806616.5007900635
743541.5007976232
682692.0008026367
624154.5007995925
568018.0007727906
514380.0007214517
463346.0006733418
415020.5006340629
369497.0005870765
326850.5005366999
287132.0004867765
250367.0004392023
216563.0003930725
185714.0003400988
157792.0002898437
132738.5002482320
110465.5002037838
90870.5001570592
73845.0001174271
59257.0000883634
46933.5000628961
36665.0000415080
28228.0000262289
21404.5000151008
15983.0000081 703
11755.5000048635
8521.5000039519
" 6094.5000036908
4305.0000034413
3006.0000032726
2076.5000026751
1419.5000019480
961.0000013379
645.0000009311
429.0000007334
283.0000005801
185.5000004208
120.5000002820
77.5000001734
49.5000000906
31.5000000335
20.0
102
-------
o
OJ
Cancer Mortality Data (Abridge Format)
...4- I. ...+. ...2. ... + . ...T. ...••-. ...4. ...+. ...S +. ...6. ...+. ...7. ...'•»-. ...S
Leukemia
OOOH3I l.'i/t OOOOTVr.7 00002l3''t7 "000202)0 0')r>nidS/»/» ri00016S'»5 00:)021S3A '.
0()010007I 100[/,00y9 000225113
All Other Cancers
000037031 OOOOT25)-'* Ouri032?16 00005222° M00071 31 tJ OOOllOys:* 0-"t019(i325 ni):)33')22('
0007r)3?.01 O.)l31'»r.r,:< O021'.)'i321 :)03-'.l'U)7l 0')/«.SfiAW)5 ')0'i5U3333 0')1{'i!T)f,Hf, 010022733
01 !5'K>;{LJf) 01/.I2-U27 'JU12'tl::7 01.'.12A127 Ol'il2'.127 Ol/. 1 2-'. 12 7
Lung
-'t't f)');;0'>oo'-o OOOOOOIMA nooooo3r>7 000001^7
0000IS225 000;)2973^ 000'"'5'tOU» 00008;:)27
Liver
OlO'ir)i)24.» On"1.')r)03''tl 00"OOOS'i') OOiOOTi1}! 0000"' V>1 I 00)0nif>0()
00000'>.'..Vv; OOOO] r,rn7 00002f)TtO 00003:'.272 000'ir>|S30 OOOOSO't.'i2 0()00'.ri'>22
0-''H)7I 37'.l 000071 "i7.:i O'»0071373 O0'i,)7l 373
-------
FORTRAN IV Cl RELEASE 2.0
HAIN
DATE = 78193
13/44/22
PAGE 0001
0001
0002
o
-tr
0003
0004
0005
0006
0007
OOOfl
0009
0010
0011
001?
0013
0014
0015
c
c
c
c
c
c
c
c
c
c
c
00000100
00000200
00000300
...DECLARATION, OIHENSION AND INITIALIZATION OF SCAURS AND ARRAVS00000400
00000500
00000600
00000700
00000800
00000900
00001000
00001100
00001200
REAL«8 LSW1(3>/'MALE','FEMALE','GENERAL'/,LSW2(2)/'DISK'.'CARDS'/,00001300
COHORT ANALYSIS FOR INCREASED RISK OF DEATH «««
REALS8 REFTBLfill,3,31/99940.0/,MORT(22,3,111/726*0.OX,ALLCAN
l(m,4,ll)/4884*0.0/,GLTABL(lll,9)/999*0.0/,ARCO(llll/lIl*0.0/,
2NOARCO(1111/111«0.0/,TDEAD(1III/I 11*0.0/,FETAL(11I)/111*0.O/,
3CHILO<1111/111*0.0/,ADULT(lll)/llieo.O/.MORTAL(22»/22*0.0/,
4CANMOR(111,10)/1110«1.0/.OOSE(9}.FOEATH,CDEATH(101,AOEATH(10I.
5INCMOR.REFHOR
ILSM3m/'NONE'.'ABSOLUTE','RELATIVE'/,LSW4(4,5)/'NONE',' ',' •,
2' »,'ACCIDENT',' (S INGLE•,')',' ».'ACCIDENT',' MULT IP','LE»•,' ',
3'CANCER C'.'OMMITTME'.'NT (SINGf,'LE )','CANCER C • ,'OMMIITME•,
4'NT .CANCER(3,10!
INTEGERS INTAGEfll0.2).BEGAGE(9),ENOAGF(9l,STRTAG(9),CtTNCY(9l,
1CPLATO(9I,ALTNCY(9).APLATO(91,KIOEXP|91,ADEXP(9),SWITCH(7),
2AGE.CAN,POP,REF.STG,SEPAGE.STATRF,TOTCAN.CANNO.BEGSTG,BEGCAN,
3SMI,SH2,SM3.SW4,SH5,SH6,SW7,CASRFP,CANREP
EQUIVALENCE (SW1,SW ITCH(1)1,(SU2,SMITCH(211,(SM3.SWITCH(3)1.
MSW4,SWITCH(4)!,(SM5,SMITCH(5M,(SM6,SWITCH(6M.(SU7,SMITCHm)
...INPUT CASE PARAMETERS - DETERMINE END OF RUN
5 READ(5,7)TITLE
7 FORMAT(20A«)
MRITE(6,7»T1TLE
REAO(5,I7,END=15MSWITCH(M,I = 1,7),NOCAN,SFPAGE,NORMAG,
I(RFGAGE(JI,J=1.9),(ENOAGE(J),J=1.9),(DOSE(J),J=1,9)
17 FORMAT(71 I ,3X.1215,/,9I5,3F10.9,/,6F10.91
IF(SM1.EO.OJGO TO 15
TOTCAN = NOCAN « 1
...INPUT REFERENCE LIFE TABLF DATA FROM DISK OR CARDS
IF(SM2.NE.1)GO TO 25
READ(e,27)(((REFTBKAGE,REF .POP] ,RFF =1 ,3) ,AGF = I , 1 11 ) ,POP= I .3 )
?7 FORMAT(3F20.10)
00001400
00001500
00001600
00001700
00001800
00001900
00007000
00002100
00002200
00002300
00002400
00002500
00002600
00002700
00002800
00002900
00003000
00003100
000032CO
00003300
00003400
00003500
00003600
00003700
00003POO
00003900
00004000
00004100
00004200
00004?00
00004400
00004500
00004600
00004700
00004800
-------
FORTRAN IV Gl RELEASE ?.0
MAIN
DATE = 78193
13/**/22
PAGF 000?
0016
0017
001P
0019
0020
0021
0022
0023
002*
0025
0026
0027
0028
0029
0030
0031
0032
0033
003*
0035
0036
0037
0038
0039
00*0
00*1
00*2
00*3
00**
C
c
c
c
c
c
c
c
c
c
c
c
c
c
c
c
25
35
37
*7
65
20
55
75
85
REWIND 8
GO TO 35
READ(5,37I((
-------
o
01
FORTRAN IV Cl
00*5
00«6
00*7
00*P
00*°
0050
00C1
005?
0053
005*
0055
0056
0057
005P
0059
00*0
0061
0062
0063
006*
0065
0066
0067
0068
PELEASF 2.0
MAIN
DATE = 7819?
13/**/22
PACE 0003
C
c
C
c
c
c
c
c
c
c
c
c
c
c
c
c
CALL CARSK(SHITCH(3).PEGAGE(J),KIDEXP<.M, DOSE(Jl,CLTNCY(CAN)
1 CPIATO(CAN).CDFATH(C«N).CHILD)
SIRTAC(J) = SEPAGF
AOFXP(J) = ENDAGE(J) - SFPAGF
CALL CARSMSWITCHm.STRTAGU) ,AOFXP(J),OPSF(J» ,«ITNCY(CAN) ,
1 APLATO(CAN),ADEATH(CAN|,ADULT)
GO TO 30
95 KIOEXP(J) = ENDAGE(J) - BEGAGE(J)
CALL CARSK(SW1TCH(3),PEGAGE(J),KIDEXP(J), OOSEf J ) .CLTNCY (CAN )
I CPLATO(CAN).CDEATH(CAN),CHILD)
30 CONTINUE
...STORE FETAL. CHILD, ADULT AND SUMMED RISKS FOR ALL AGES
- CALCULATE RADIATION MORTALITY FOR RELATIVE RISK CASES
00 40 AGE=1,110
ALLCAN(AGE.l.CAN) = ALL CAN(AGE,1.CAN) « FETAL(AGE) *
I CANMOR(AGE.CAN)
ALLCAN(AGF.?.CAN| = ALLCAN(AGF .?^CAN) « CHILD(AGF) '
1 CANMOR(AGE.CAN)
ALLCANUGE.3.CAN) = ALLCAN (AGE .3 .CAN ) « ADULT(AGF) '
I CANMOR(AGE.CAN)
AILCAN(AGF,4.CAN) = ALLCAN(AGE ,4 .CAN I « (FFTAL(AGF) »
1 CHILD(AGE) * ADULT(AGE)) * CANMOR(AGE.CAN)
...STORE TOTAL RADIATION RISK FOR ALL AGES
00 50 STG=1 ,*
ALLCAN(AGE.STG.TOTCAN) = ALLCANtAGE,STG,TOTCAN) «
1 ALLCAN(AGE.STG.CAN)
50 CONTINUE
*0 CONTINUE
...INITIALIZE STAGE VECTORS FOR NEXT CANCFR
00 60 AGE=1,1I1
FETAL(AGE) = 0.0
CHILD(AGE) = 0.0
ADULT(AGF) = 0.0
60 CONTINUE
10 CONTINUE
...DETERMINE TYPE AND FORMAT OF ADDITIONAL RISK
GO TO(105,115,115,125,1?5I,SM«
...INPUT NON-RADIATION RISK VALUES - THESE RISKS ARE NOT SUBJECT
MORTALITY CONVERSION
.00009700
00009800
00009900
00010000
00010100
00010200
000103CO
00010*00
,00010500
00010600
00010700
00010800
OOOI09CO
00011000
00011100
00011200
00011300
00011*00
00011500
00011600
00011700
00011800
00011900
00012000
00012100
00012200
00012300
00012*00
00012500
00012600
00012700
00012800
00012900
00013000
00013100
00013200
00013300
00013*00
00013500
00013600
00013700
00013800
00013900
0001*000
0001*100
0001*200
0001*300
0001**CO
-------
FOR IRAN IV Gl RELEASE ?.0
HAIN
DATE = 78193
13/44/??
PACE 0004
0069
0070
0071
007?
0073
00 74
0075
0076
0077
0078
0079
OOflO
OOP1
OOP?
0083
OOP*
OOR5
OOP6
0087
OOP8
OOP9
0090
00"!
009?
00«>3
0094
0095
0096
0097
009P
0099
0100
0101
0102
0103
010^
0105
115
C
C
C
C
1
C
C
C
125
105
CALL ACCRSMSW4,BEGAGE(l).ENDAGE(l).CASREP,NnARCO)
GO TO 105
...INPUT NON-RADIATION RISK VALUES - THESE RISKS ARE SUBJECT
I MORTALITY CONVERSION
CALL ACCRSMSV4,BEGAGE(1),ENGAGE(1 ) .CASREP ,ARCO)
...GENERATE LIFE TABLE
STATRF = NORMAG 4 1
GLTABl(STATRF.4) = REFTBL»STATRF,?,SU1)
ADDEAO = 0.0
00 70 AGE=STATRF,110
INTAGEfAGE.?) = AGE
INTAGFUGE.l) = INTAGEfAGE.?) - 1
REFMOR = REFTBLUGE.1.SW1) / < 1 .0-r.5«REF TBl (AGE, 1 ,SN1 ))
GLTABLfAGE.Z) = ARCO(AGF)
GLTABLUGE.?) = GLT ABL ( AGE .? » / (1 ,0-0.5«GL1ABl(AGE,?11
INCHOR = GLTABLUGE.?) « ALLCAN (AGE ,4 .TOTCAN» « NOARCO(AGF)
GLTABLUGE.1) = REFMOR / (1.0*0.5*(REFMOR « INCMQRM
INCMOR / (1.0*0.
GLTABLUGE .1 ) «
GLTABL(AGF.3) «
= GLTABL(AGE.4)
70
135
C
C
C
155
165
GLTABLUGE.?) =
GLTAPLUGE.3) =
GLTABL(AGE.5) =
GLTABLUGF«1.4)
GLTABLUGE.6) =
GLTABL(AGE.9) =
AOOEAO = AODEAO
CONTINUE
AOOEAO = ADOEAO
AGE = 110
GLTABLUGE.7) =
GLTAPL(AGE.B) =
AGE = AGE - 1
CLTABL(AGE,7) -
GLTABL(AGE,8) =
,5«(RFFMOR « INCMOR))
GLTABL(AGF,7)
GLTABL(AGE,4)
- GLTA8L(AGE,5)
(GLTABLUGF,4)«GLTABl(AGF«1.4)) / ?.
GLTABl (AGE.?) « GL TABL ( AGE ,4 )
* GLTABLUGE .9)
« (100000.0/REFTBL (STATRF,?,SWIM
GLTABLUGF.6)
GLTABLUGF.7)
GLTABL(AGF.6)
GLTABL(AGF,7)
RFFTBL(111.3.SW1)
GLTABL(AGE,4)
GLTABL(AGE«1,7)
GLTABLUGF.4)
IF(AGE.GT.STATRF)GO TO 135
...DETERMINE TYPE OF ADDITIONAL ANALYSIS AND ASSIGN ORGAN ANP
GO TOm5.155,165.175),SW5
BFGCAN = TOTCAN
8EGSTG = 1
GO TO 145
PEGCAN = 1
BFGSTG = 4
GO TO 145
OC014500
00014600
000)4700
00014ROO
TO 00014900
00015000
00015100
00015200
00015300
00015400
00015500
00015600
00015700
00015BOO
00015900
00016000
00016100
00016200
00016300
00016400
00016500
00016600
00016700
00016000
00016900
00017000
00017100
00017200
00017300
00017400
00017500
00017600
,00017700
00017800
00017900
oooieooo
00018100
OOOIP200
00018300
ST«G00018400
00018500
00018600
00018700
00018800
00018900
00019000
000 I'9100
00019?00
-------
FORTRAN IV Gl RELEASF ?.0
MAIN
DATE = 7B193
13/44/P2
000«i
o
CD
0106
0107
0108
0109
0110
0111
0112
0113
0114
0115
0116
0117
0116
0119
0120
0121
0122
0123
0125
0126
0127
0128
0129
0130
0131
0132
0133
0134
C
C
C
175
145
185
195
205
BECCAN
BEGSTG
C
C
C
215
C
C
C
100
90
80
C
C
C
C
C
C
...CALCULATE FRACTION OF TOTAL DEATHS FOR ALL AGES
00 80 AGE*STATRF,111
IF(GLTABL(AGE,9).E0.0.01GO TO 80
GO T0(185,195,195,205,205),SW4
TDEAO (AGE) = GLTABL(AGE.9)
GO TO 215
NOARCO(AGE) = NOARCO(AGE) « GLTAfiL(AGF ,4)
NOARCOMI1) - NOARCO(lll) « NOARCO(AGE)
TDEAD(AGE) * GLTABL (AGE ,91 - NOARCO(AGE)
GO TO 215
ARCO(AGE) = (ARCO(AGE)«GLTABL(AGE,9)) / (ALLCAN(AGE ,4 .TOTCAM*
1 ARCOUGEI)
ARCO(lll) * ARCOM11) « ARCO(AGE)
TOEAO(AGE) = GLTABL(AGE,91 - ARCO(JCE)
...CALCULATE AND STORE FRACTION OF TOTAL DEATHS FOR EACH CANCER
IF(SM3.E0.1)GO TO 80
DO 90 CAN*BEGCAN.TOTCAN
...CALCULATE AND STORE FRACTION OF TOTAL DEATHS FOR EACH
00 100 STG=BEGSTG,4
ALLCAN(AGE,STG,CAN) = (ALLCAN(AGE ,STG ,CAN)«TDEAD(AGE ) /
1 ALLCAN(AGE,4,TOTCAN1)
ALLCANdll.STG.CAN) = ALLCAN ( 111 ,STG ,CAN) *
\ ALLCAN(AGE.STC,CAN)
CONTINUE
CONTINUE
CONTINUE
...CALCULATE YEARS OF LIFE LOST AND DECREASE IN LIFE EXPECTANCY
296
475
6
YLL = IREFTBLISTATRF,3.SH11-GLTABL(STATRF.7M
1REFTBL(STATRF,2,SW1M
AVGVLL * YLL / ADDEAD
OLE = YLL / 100000.0
...OUTPUT TITLE AND CASE PARAMETERS
WRITE(6,296)
FORMATMHl.* •)
HR1TE(6,6)
FORMAT(IH ,T2,» I
(100000.0/
00019300
00019400
00019500
00019600
00019700
00019800
00019900
00020000
00020100
00020200
00020300
00020400
00020«iOO
00020600
00020700
00020800
00020900
00021000
00021100
00021200
00021300
00021400
00021500
00021600
STAGE 00021700
00021800
00021900
00022000
00022100
00022200
00022300
00022400
00022500
00022600
00022700
00022800
00022900
00023000
00023100
00023200
00023300
00023400
00023500
00023600
00023700
00023800
00023900
•,00024000
-------
FORTRAN IV Cl RELEASE 2.0
MAIN
DATE = 78193
13/44/22
FACE OC06
o
ID
0135
0136
0137
0138
0139
0140
01*1
0143
0144
01*5
0146
0147
0148
0149
0150
0151
015?
0153
0154
0155
0156
0157
0158
0159
0160
0161
016?
0163
0164
0165
0166
I • •
WRITFI6.16)
16 FORMATC1H ,T?, • | • ,7133, • | • J
MRITE(6.?6)TITLE
?6 FORMATUH ,T?, • 1 • .T?7,?OA4 ,T 133, • 1 • >
WRITE(6.16)
WRITF(6.36)LSW1(SW1 )
36 FORMATUH ,T2, M * .T54 . 'POPUL AT ION AT RISK: • ,A8.T 1 33 .• | • 1
MRITE(6.46)LSW7(SM7«H.LSW2(SW2)
46 FORMAT (1H ,T? , « | • ,T 7, 'NUMBFR OF DOSE RATES: ' .A8.T79 ,'RFFERFNCE
1MABLE INPUT SOURCE: • .AB.T1 33. • I • )
URITE(6.56)LSU3(SM3).(LSW5(L.SW5).L=I,21
56 FORMATC1H ,T 2. M • ,T 7. 'RAOI AT ION R 1 SK MODEL: • ,A8 ,T88 .' ADD IT 1 ON • ,
1'AL ANALYSIS! • ,2A8 ,T 1 33 ,' 1 • )
WRITE (6. 66)1 LSW4(L.SW4).L=1.4).(LSU6(L,SW6),L=1.3)
66 FORMAT (1H ,T2. • 1 • .T 1?. 'ADOI T IONAI RISK: • ,4 A8 ,T90,' ADO I Tl ONAL ',
1'OUTPUT: '.3A8,T133.'|M
MRITE(6,16)
HRITE(6.6)
WRITEI6.386!
386 FORMATdH ,T?, • | • ,T67, • | • ,T 1 33 . • I • )
WRITE (6. 76)
76 FORMAT (1H .T?. • | • .T23 . •**« INPUT DATA *** • ,T67, • 1 • ,T90, • **< •
!• OUTPUT DATA «**• ,T133. ' I M
HRITE(6,386)
C
C ...OUTPUT CASE VARIABLES AND STATISTICS
C
WRITE(6,86)
86 FORMATMH ,T?, • | • .T 15 . 'DOSE • ,T46. • AGF INTERVAL* .T67.M'.
1 T.I 33, MM
TO 1?0 M^1.SM7
WRITFJ6,96)DOSE(M>.BECACE(Ml ,FNPAGF(M)
96 FORMATC1H ,T? ,• I • ,T 1?.F 15 .9,T47, I3.T5 1 ,•- • ,T53, 13 ,T67, • 1 • ,T 133
1 MM
1?0 CONTINUE
WRITE (6.1 06 )SEP AGE. ADDEAD
106 FORMATC1H ,T ?, M • .T 1 1 . 'CHILD AGE INTERVAL ='.T49,«0 -I.153.l3,Tf
IM'.TTI. 'NUMBER OF PREMATURE DEATHS = • .T 1?1 ,F 1 1 .5, T 1 33 , M M
WRITE (6, 1161 SEP AGE. OLE
116 FORMATdH ,T ?, M • .T 1 1 , «ADUL T AGE INTERVAL =t,T47,|3,1 - 110°.
lT67,Mt.T71. 'DECREASE IN POPULATION LIFE EXPECTANCY =',T1?1,F11.
?T133.'|M
WRITE(6,1?6)NORMAG,YLL
126 FORMATMH .T 2. • I • .T 1 1 . 'OUTPUT PAlA PASFO ON ACF INIFRVAL =».1
-------
FORTRAN IV GI RELEASE 2.0
MAIN
DA IF = 78193
13/44/P2
PAGE CC07
0167
0166
0169
0170
0171
0172
0173
017*
0175
0176
0177
0178
0179
OlflO
0181
0182
01R3
0184
01P1
01P6
0187
018P
01P9
0190
0191
0192
01*)?
019*
019?
0196
0197
019P
0199
YEARS OF LIFE LOST PER*,
C
c
C
WRITF(6,136)AVGYLL
136 FORMATdH ,T2,• I • ,T67,'I ' ,T71,'AVERAGE
!• PREMATURE DEATH = •,F12.5,T133,•I•I
WRITE(6,146>
146 FORMATdM ,T2, • I • ,T67, • I • ,T1 33, • I • )
MRITE(6.6t
WRITE(6.16)
|F(SU3.E0.1)GO 10 485
...OUTPUT CANCER VARIABLES
MRITE(6,16)
WRITE(6.156)
156 FORMATdH ,T2,• I •,T9,'CANCER •,T42,'FETAL•,T75,'CHILD*,TI08 ,
166
1*AOUL1*.T133.*|()
MRITE(6,166)
FORMATdH ,T2,trt,T31,'LATENCY PLATEAU DEATH
I," PLATEAU DEATH RATE*.T97.'LATENCY-' PLATEAU
00028900
00029000
00029100
00029200
00029300
00029400
00029500
00029600
00029700
00029800
00029900
00030000
00030100
00030200
00030300
176
130
00030400
RATE»,T64,HATFNCY'00030500
DEATH RATE»,TI33, 00030600
2tlil 00030700
WRITEI6.I6) 00030800
DO 130 CAN*1,NOCAN 00030900
WRITE(6,176MCANCER(K,CAN).K=1,3I,FLTNCY,FPLATO.FDEATH, 00031000
1 CLTNCY(CAN}.CPLATO(CAN),CDEATHfCAN),ALTNCY(CAN).APLATOICAN},
2 AOEATHCCANI
FORMATdH ,T2,M(,T9,3A4(T31,I5,T40(I5,T46,F10.3.T64,I5,T73,I
1 T79,F10.3,T97,I5,T10B,15,T114,FI0.3,T133,'I()
C
C
C
CONTINUE
WR1TE(6(16)
WRITE(6.6I
WRITF(6,16)
.
...OUTPUT CANCER DEATHS FOR ALL STAGES
WRITE(6,186I
186 FORMATUH ,T2, • I • ,T27, »C ANCERf ,T54 ,»FE TAL • ,T69, 'CHILD' ,T8 4 ,
l»AOULT».T104,«TOTALt,T133.t r«>
WRITE(6.16)
GO T0(485, 535, 255, 2651, SH5
1F(SH5.NE.1>GO TO 255
535 DO 140 CAN=1,NOCAN
WRITE(6,196)(CANCER(K,CAN1,K=1.31
196 FORMATdH ,T2 ,M ' ,T27,3A4 , Tl 33, • I • »
140 CONTINUE
WR|TE(6,2061 ( ALLCANf 1 1 1 ,STG .TOTCAN) ,STG = I ,4 »
206 FORMATdH ,T2, • I • ,T27, »TOT AL • . T52 ,F5 .2, T67.F5 .2,T82 ,F5 .2, Tl 0? ,
lF5.2,TI33,Mt)
GO TO 245
255 IF(SW5.NE.2)GO TO 265
00031100
00031200
00031300
00031400
00031500
00031600
00031700
00031800
00031900
00032000
00032100
00032200
00032300
00032400
00032500
00032600
00032700
00032800
00032900
00033000
00033100
00033200
00033300
00033400
00033500
00033600
-------
FORTRAN IV Gl RELEASE 2.0
MAIN
DATE = 78193
I3/**/22
PACE 0008
0200
0201
0202
0203
020*
0205
0206
0207
020P
0209
0210
0211
0212
0213
021*
0215
0216
0217
0218
0219
0220
0221
0222
0223
022*
0225
0226
0227
0228
0229
0230
0231
0232
0233
023*
216
150
226
265
236
160
2*6
2*5
C
C
C
*85
275
256
285
C
C
C
295
266
C
C
C
505
DO 150 CAN=1,NOCAN
MR I TE (6,21 61 ( CANCER (K, CAN ) ,K =1,31, ALLCANd 11,*, CAN)
FORMAT (1H ,T2,M',T27,3A*,T102,F5.2,T133,'I'I
CONTINUE
URITE(6.226)ALLCAN(111.*,TOTCAN)
FORMAT MM ,T2,' I ' ,T 27, 'TOT AL ' , T102 ,F5.2 ,7 1 33, ' I ' )
GO TO 2*5
DO 160 CAN=1,NOCAN
WRlTE(6,236HCANCER(K.CAN),K=1.3),(ALLCANd 1 1 . 1 ,C AN» , 1 = 1 ,* 1
FORMAT (1H ,T2,'I',T27,3A*,T52,F11.5,T67,F11 .5.T82 ,FI 1 .5 ,T 1 02 ,
1 F11.5,T133t*l*)
CONTINUE
WRlTE(6,2*6MALLCANdll,STG,TOTCAN»,STG = l.*l
FORMAT (IH ,T2,Mt.T27,'TOTAL',T52,F11.5,T67,F11.5,T82,F11.5,TI02,
1F11.5,T133,'I')
WR1TE(6.16)
WRITE(6,6)
WRITE(6,16)
...OUTPUT ADDITIONAL RISK
GO TO<295,275,275.285.285),SW*
WRITE (6.256)NOARCO< I 111
FORMATdH. T2.llt.T27. 'NUMBER OF DEATHS CAUSER BY ',
1 'NON-RADIATION Rl SH S' , T10* ,F 11 .5,T 133 . ' 1 ' )
HR|TE(6,16)
WRITE(6.6)
HRITE(6,16)
GO TO 295
WRITE(6.256)ARCO(111)
URITE(6,I6)
WRITE(6.6I
URITE(6.16)
...OUTPUT TOTAL NUMBER OF INCREMENTAL DEATHS
WRITF(6.?66)AODEAO
FORMATdH ,T2,' |',T27, 'TOTAL NUMBER OF INCREMENTAL OEA THS ' ,T 10* ,
1F1 1 .5 ,T133»' I ' )
URITEI6,16)
WR|TE(6.6)
...OUTPUT GENERATED LIFE TABLE
GO TO(3*5,505,515,505),SM6
CALL LTHEAO(SMI I
INTBLK = (STATRF « *) / 5
DO 170 AGE=STATRF,110
00033700
00033800
00033900
0003*000
0003*100
0003*200
0003*300
0003**00
0003*500
0003*600
0003*700
0003*800
0003*900
00035000
00035100
00035200
00035300
00035*00
00035500
00035600
00035700
00035800
00035900
00036000
00036100
00036200
00036300
00036*00
00036500
00036600
00036700
00036800
00036900
00037000
00037100
00037200
00037300
00037*00
00037500
00037600
00037700
00037800
00037900
00038000
00036100
00038200
00038300
00038*00
-------
FORTRAN IV Gl RELEASE 2.0
MAIN
tlATF = 78193
13/**/2?
PACF 000°
0235
0236
0237
02 3P
0239
02*0
0241
0242
0243
02*5
02*6
02*7
02*8
02*9
0250
0251
0252
02«>3
025*
0255
0256
0257
0258
0259
0260
0261
0262
0263
026*
0265
0266
0267
0268
0269
0270
0271
,T 71 , • | • ,TB3 , •
MRITF(6,276)( INTAGF ( AGE . J ) ,J = 1 ,2 ) . (GL T ABl (AGF ,N),N=1 ,9)
276 FORMATdM ,T2 , M • .T* .1 3. •- », 13, • I *,FI2.IO,* I *,F12.10.* I •
1 FI2.10.' |.*.F1I.*,* I •,F9.*.« I ».F10.*,1 I '.F12.*,' I •,
2 F9.6,» I •.F8.*,T133,> I')
LINE = MOO(ACF-1.5) « 1
IF(LINF.EQ.5)GO TO 315
170 CONTINUE
GO TO 325
315 WR1TF(6,286)
286 FORMAT (1M ,T2, • I • .T 12 ,• I • ,T27, • | • . T*2, • | • ,157 .
1T96.'II,T111,M t.T123.»|ttT133.Mt)
NOW6LK = (AGE * *)/5
IF(NOWBLK-INTBLK.F.Q.7)GO TO 335
GO TO 170
335 CALL LTHFAO(SWl)
INT6LK = NOUBLK « 1
GO TO 170
325 WRITE(6,6)
WRITE (6 .6)
...DETERMINE TYPE OF ADDITIONAL OUTPUT
515 GO TO(3*5,3*5.355,365,355).SW6
...OUTPUT STAGE TABLE
355 CALL STHEAD
STATRF * 1
1NTBLK = (STATRF**) / 5
DO 190 AGE=STATRF,110
HR1TE(6,336)( INTAGE ( AGE . J) ,J = 1 , ? ) ,
1 (ALLCAN(AGFtSTG.TOTCAN),STG=l ,* )
336 FORMAT (1H ,T28, • | • ,T36 , I 3 . •- • , 1 3 ,T50 . • I • ,755 ,F5 .2 ,T6 3 , • I • ,T66 ,
1 F5.2,T73.tltiT77,F5.2,T86,»l • ,T93,F5 .2.T 105 . • I ' ) .
LINF = MOOUGE-1.5) « 1
IF(LINE.EQ.5) GO TO 375
190 CONTINUE
GO TO *05
375 HRITE(6.316)
316 FORMAT (1H ,T 28 , 'I • . T50.» I • ,T63 . • I • ,T 73, • I • ,T86 , • I • , T 105 , • | • )
NOWBLK = (AGE**) / 5
1F(NOWBLK-INTBLK.E0.7) CO TO 395
GO TO 190
395 CALL STHEAO
INTBLK = NOWBLK * 1
INTBLK = NOWBLK « 1
GO TO 190
*05 WR1TE(6.306)
C
C
C
•
C
C
C
00038500
, 00038600
00038700
00038800
00038900
00039000
00039100
00039200
00039300
'.00039*00
00039500
00039600
00039700
00039800
00039900
000*0000
000*0100
000*0200
000*0300
000*0*00
000*0500
000*0600
000*0700
000*0800
000*0900
000*1000
000*1100
000*1200
000*1300
000*1*00
000*1500
000*1600
000*1700
000*1600
000*1900
000*2000
000*2100
000*2200
000*2300
000*2*00
000*2500
000*2600
000*2700
000*2800
000*2900
000*3000
000*3100
000*3200
-------
IV Gl PELFASF P.O
MAIN
DATE = 7P193
13/44/??
PAGE 0010
OP7P
OP73
OP74
0?7*
0?7fc
OP77
OP7P
0?7°
OPPO
OPP1
OPPP
OPP.3
OPP4
OPP1!)
OPPt
OPP7
OPP9
OP90
CP"?
OP93
OP94
OP95
0?°6
OP97
OPSP,
0?«?9
03CO
0301
0303
03P4
030C
3UO
C
C
C
36*
445
346
POO
41*
366
43*
4P5
i*\ A
3 vO
C
C
C
345
WR|TE(6,306)
...OUTPUT CANCER TABLE
TF(«;W*.E0.3)GO TO 345
CALL CTHEAO(CANCFR)
STATRF = 1
1NTBLK = (STATRF«41 / *
00 POO AGE=STATRF,110
WRITE (6,346 )( INT AGF (AGF.J),J?1 ,P),ALLCAN( AGF
1 (ALL CAN (AGF ,4 .CAN ) ,C AN = 1 ,NPC AN )
FORMATMH ,T?.M ' ,T 7 ,1 3 , •- • , I 3 . T 1P3, • 1 '.TIP*
1 t|<,T?3,F5.2tT33tt|t,T3PtF*.?,T4P,t|t,T53,FK
? T7fl,' I»,TP3,F5.?,T93,' I ' .T9P. ,F* ,?,T 108 ,' 1 • ,T
LINE = MOD(AGE-1,5) « 1
1F(L1NF .E0.5) GO TO 41*
CONTINUE
GO TO 425
WR1TF(6,366)
lT10P,'|'.Tl?3,f l*.T133,t 1")
NOWPIK = (AGF«4) / 5
IF(NOWBLK - 1NTBLK.F0.7) GO TO 43*
GO TO POO
CALL CTHFAO(CANCFR)
1NTPIK = NOWPLK « 1
GO TO POO
WRITE (6,366)
WRITE (6.6)
URITF (6,366)
WR|TF(6,356)ALLCAN( 111 ,4 .TOTCAN ),( ALLC AN ( 1 1 1 .4
IT 33," 1 t,T3P,F6.?,T4P,tli ,T5 3 ,F 6.P , T6 3, ' 1 ',T6P,
?F6.?.Tf'3,1 1 *,T9e,F6.?. Tl OP," |», T113, F6.P.T1P3 ,
WRITF(6,366)
WRITE (6, 6)
WRITE (6, 6)
...INTIALI7E MATRICFS FOR NFXT CASF
CONTINUE
PO PIO AGF = 1 ,111
TPFADUGEI = 0.0
APCO(AGF ) = 0.0
NOARCOUGF ) = 0.0
00 ??0 N=l,9
; ',UUO* HUV
00043400
00043500
00043600
00043700
00043800
000439CO
00044000
000441CO
00044POO
00044300
,4, TOTCAN), 00044400
00044*00
,F5.?,TI33, ' I '.TIP, 00044600
.P.T63,' 1 • ,T6P,F*.P, 00044 700
113,F*.P) 00044POO
00044900
0004*iOOO
0004*100
0004*?00
0004*300
0004*5CO
0004*600
0004*700
0004lcflCO
00045900
00046000
0004 f 100
C0046200
00046300
00046400
,1 ) ,I = l,NOr AN) 000465CC
i T i Q 1 1 § T?^ f f\ 7 r\f\r\^f^,f^f\f\
fiinfi ^icjt*rt«r» wvV'~i3D(.'»"
F6.P.T7F ,* 1 *,TP3, 0004f 7CO
•1') 00046PCT
00046900
00047000
000471CO
0004 7POO
00047300
00047400
00047500
00047600
00047700
000«7POO
00047900
0004POOO
-------
FORTRAN1 IV Gl RFLFASE 2.0
MAIN
PATF = 7P193
13/44/P2
PAGE 0011
0307
030P
0309
0310
0311
031?
0313
0314
0315
0316
GITABL(AGF.N) * 0.0
00 230 STG=1,4
ALLCAN(AGF,5TG,N>
?30 CONTINUE
220 CONTINUE
210 CONTINUE
1F(CASREP.E0.1)GO TO 5
GO TO Y>
15 STOP
END
0.0
00048100
00046200
0004R300
00048400
0004P500
00048600
00046700
0004flPOO
00048900
00049000
-------
FORTRAN IV Gl RFIFASE 2.0
MAIN
DATE = 78193
!3/**/?2
FACE 0001
C
r
c
OPOl
000?
0003
000*
0005
0006
0007
0008
0009
0010
0011
001?
0013
0014
NON-RADIATION RISK SUBROUTINE «««
SUBROUTINE ACCRSK (SW* .REGAGE .ENGAGE ,CASREP , AODRSK )
REAL*8 AOORr.K(l I,SINRSK
INTEGER SW*.AGE,BEGAGE.ENGAGE,CASREP
GO TOJ5,15,?5,15.25).SW*
15 READJ5.71CASREP.SINRSK
7 FORMAT(I5,F10.9»
00 10 AGE=BEGAGE.ENPAGF
APPRSK(AGE) = SINRSK
10 CONTINUE
GO TO 5
?5 REAO(5,17)CASREP»(AOORSKfAGE).AGF=l.llp)
17 FORMAT«I5/1«(8F10.9/))
5 RETURN
END
00049100
000*9200
000*9300
000*9*00
000*9500
000*9600
000*9700
000*9800
000*9900
00050000
00050100
00050200
00050300
00050*00
00050500
00050600
00050700
-------
FORTRAN IV Cl RELEASE 2.0
MAIN
OA1E = 7H193
13/44/??
PAGE 0001
0001
000?
0003
0004
0005
0006
0007
OOOfi
0009
0010
0011
001?
0013
0014
C
C
C
15
10
««« FETAL RADIATION RISK SUBROUTINE
SUBROUTINE FFTRSK CSH3 .FLTNCY, FPL A TO. DOSE ,PE ATMS. IXR )
REAL«6 IXR(l), DEATHS. DOSE
INTEGER SW3, START, END. FLTNCY, FPL A TO
IF(SM3.EQ.3)GO TO 5
RISK = DOSE « (DEATHS/1000000.0)
GO TO 15
RISK = DOSE * DEATHS
START = FLTNCY « 1
END = FLTNCY * FPLATO
DO 10 I=START,END
IXR(I) = RISK
CONTINUE
RETURN
END
OC050BCO
00050900
00051000
00051100
00051?CO
000513CO
00051400
OC051500
00051600
00051700
00051800
00051900
000«>?000
ooo5?ion
0005??00
0005?3CO
-------
FORTRAN IV Gl RELEASE 2.0
MAIN
OATF = 78193
13/44/P2
PAGE 000!
C
c
C
*** CHILD C AOULT RADIATION RISK SUBROUTINE
0001
0002
0003
0004
0005
0006
0007
0008
0009
0010
0011
0012
0013
0014
0015
0016
0017
0018
0019
0020
0021
0022
0023
0024
0025
0026
0027
SUBROUTINE C ARSK(SW3,BEG AGE .YRSFXP.DOSE ,LATNC V .PLATOE, DEATHS ,
REAL«8 IXR(l)
INTEGER BEGAGE.YRSFXP.PLATOF.SU3,YR.AGE.BEGHLF,STRTAG,FNDAG
GO TO <5,5,151,SW3
5 RISK = DOSE « (DEATHS/1000000.0)
GO TO 25
15 RISK = DOSE « DEATHS
25 BEGHLF = BEGAGE « LATNCY 4 l
00 10 YR=1.YRSEXP
IXR(BEGHLF) - IXR(BEGHLF) « 0.5 « RISK
STRTAG = BEGHtF 4 I
ENDAG = BEGHLF 4 PLATOF - 1
IF(ENOAG.LE.110)GO TO 35
IF(ENOAG-PLATOE.GE.110)GO TO 45
ENDAG = 110
35 00 20 AGE'STRTAGtENDAG
IXR(AGE) = IXR(AGE) 4 RISK
20 CONTINUE
BEGHLF = BEGHLF 4 1
IF(ENOAG.EQ.110)GO TO 10
IXR(ENOAG4l) = IXR(ENOAG4l) « 0.5 « RISK
10 CONTINUE
45 DO 30 AGE=1.110
IXR(Ill) = TXR(lll) 4 IXR(AGF)
30 CONTINUE
RETURN
FND
1XR)
00052500
000*2600
00052700
00052900
00053100
00053200
00053300
00053400
00053500
00053600
00053700
00053800
00053900
00054000
00054100
00054200
00054300
00054400
00054500
00054600
00054700
00054800
00054900
00055QOO
00055100
0005«2CO
00055300
00055400
00055500
00055510
-------
FORTRAN IV Cl RFLFASE 2.0
MAIN
DATE = 7P193
13/44/22
PAGE 0001
c
c
c
«*«
LIFE TABLE HEADING SUBROUTINE
**«
0001
000?
0003
0004
0005
OOOfc
0007
oooe
0009
0010
0011
001?
0013
0014
0015
0016
0017
ooie
0019
00?0
0021
00?2
0023
0024
0025
0026
00?7
0028
0029
63
83
125
60
135
145
61
62
70
71
SUBROUTINE LTHEAD(SWl)
INTFGFR SW1
WRITE(6,63)
FORMATdHl,' M
WRITE(6,61)
IF(SWI.EQ.I) GO TO 125
IF(SW1.E0.2) GO TO 135
UR1TE(6.831
FORMATC •,T2,M'.T27,'GENERATED LIFE
1' POPULATION: UNITED STATES, 1969-71'
GO TO 145
WRITE(6.60)
FORMATC ».T2.M',T36, 'GENERATED I If_-E TABLE FOR MALES: UNITED ',
1'STATES 1969-71',T133,'IM
GO TO 145
WRITF<6,84)
FORMATC ',T2.Mf.T35,'GENERATED LIFE TABLE FOR FEMALES: UNITED'.
1' STATES 1969-71',T133,MM
UR1TF(6,61)
FORMAT C ' ,T2, • I ' ,
TABLE FOR THE GENFRAL',
'.T133.M M
00055600
00055700
00055800
00055900
00056000
00056100
00056200
00056300
00056400
00056500
OOOS6600
00056700
00056800
00056900
00057000
00057100
00057200
00057300
00057400
00057500
00057600
00057700
r
IM
P p •»•••••• *•*»****•. ••_.
WRITE<6.62>
FORMATdH ,T2,Mf,T12,'l',T27,M',T42
l'l',T96,M',Tlll,'l',T123,M'.T133,M
URITF(6,701
FORMATdH ,T2,M'.T3,'X TO X«T l',T18
1T42,M',T48,'TQXR',T57,M'.T63,'IXR',
2T88,'TLXR»,T96t»|t.TI02.MXR.',Tni.M
3MXRLXR',T133,MM
URITE(6.62>
NRITE(6,61)
URITE(6.62)
MRITE(6,71)
FORMATdH ,T2,M'.T4,'YEARS',T12.M'.
l'|',T83,Mt.T96,Ml.Tlll,M',T123,'|'
WRITEI6.6?)
RETURN
END
t
M
I,'TOX',T27,'|' ,T33,'IXR'f
T71,M',T76,'OXR',183,Mt.
',T116,'EXR',T123,M',T126,
T27,M'.T42.'lf,T57,'|',T71,
,T133,'IM
0005R100
00058200
00058300
00058400
0005P500
00058600
00058700
00058800
00058900
00059000
00059100
00059200
00059300
00059400
00059500
00059600
00059700
-------
FORTRAN IV Cl RELEASE 2.0
HAIN
PATE = 7B193
13/44/22
PAGE 0001
0001
000?
0003
0004
0005
0006
OO07
OOOP
0009
0010
0011
001?
0013
0014
0015
0016
0017
c
C **« STAGE TABLE HEADING SUBROUTINE «**
C
SUBROUTINE STHEAD
UR1TF(6.6)
6 FORMAT (1H1,« •)
URITF(6.16>
WRITE(6.26)
26 FORMAT! 1H ,T28 . • I • , T33, • AGE DISTRIBUTION OF RADIATION «,
1* DEATHS BY STAGE FOR ALL CANCERS COMB INFO • ,T 105 , « I • )
URITE(6,16)
MRITF(6,36)
36 FORMATMH ,T28 , • 1 • , T50. • 1 • ,T63 . • I • ,T 73, • I • , T86 ,' | • , T 105 . • | • )
WR1 TE (6«46)
46 FORMAT (1H ,T28,Mt.T38,tAGESt,T50,*l • ,T55, »F E T AL • ,T 63, • I',T66,
1 »CH ILD '. T 73, •|'tT77,t ADULT* ,T86,« I t,T93,tTPTAl *,TI05,1 |» J
HRITF(6,36»
WRITE!6,16)
WRITE(6,36)
RETURN
END
00059800
00059900
00060000
00060100
00060200
00060300
00060400
• °
00060700
00060800
00060900
00061000
00061100
00061200
00061300
00061400
000615CC
00061600
00061700
00061800
00061900
00062000
-------
FORTRAN IV Gl RELEASF 2.0
MAIN
OATF = 7P193
13/**/22
0001
ooo?
0003
000*
0005
0006
0007
0008
0009
0010
0011
0012
0013
COM
0015
0016
0017
OOIP
0019
««« CANCER TABIE HEADING SUBROUTINE
SUBROUTINE CTHEAD(CANCFR)
REAL** CANCERC3.10)
INTfGFR CAN
WRITE <6,6 I
FORMAT(IH1,« •)
WRITE(6, 16)
16
?6
36
*6
FORMATdH
1'— -
,T?.M-
WR1TFC6.26)
FORMATMH ,T2,' ',T37,'Ar,F DISTRIBUTION OF RADIATION',
1* DEATHS BY CANCER TYPE FOR ALL STAGES COMB INFO•,T133,' '
WR|TE(6,16)
WRITFC6.36)
FORMAT(1M ,T2,'I',T18,•I•,T33,•|',f*8,'|',T63,'|',T78,'I'
lT108,'|t,T123,'l',T133,'l')
WRITF(6,*6M (CANCER(K,CAN).K=1 ,3I.CAN=1 ,7)
FORMATdH ,T2,'I',T9,'AGES',T18,'I ' ,T33 , ' I • ,T*P, • | • ,T63 , '
l'l',T93,' I',T108,M',T123,M',T126,'10TAL',T133,'I',T20
WRITF(6,36I
NRITFI6.161
WRITE(6,36)
RETURN
END
OC062100
00062200
00062300
00062*00
00062500
00062510
00062600
00062700
00062800
',00062900
',00063000
00063100
00063200
0006^300
) 00063*00
00063500
00063600
,T93,'|',00063700
00063800
00063900
0006*000
0006*100
0006*200
0006*300
00064*00
0006*500
0006*600
0006*700
I',T78,
,T35,
-------
UNITED STATES ENVIRONMENTAL PROTECTION AGENCY
DATE: OCT 3 1
SUBJECT: Definition of Abbreviations Used in the
CAIRD Code Life Tables
'"(/
FROM: Tang Rerisen .' ,t
Bioeffects Analysis Branch (ANR-460)
TO: See Below
The computer code for Cohort Analysis of Increased Risks of Death
(CAIRD) by John R. Cook, Dr. Byron M. Bunger and Mary K. Barrick is used
by CSD for radiation risk calculations. Frequently the abbreviated
terms in the life table headings included in the CAIRD output data need
further explanation. These terms and their definitions have been
briefly summarized in the attaclunent to this memorandum.
This summary might be of help to users of this code, particularly
since the interpretation of the output data in terms of a stationary
population is not explained in the CAIRD manual.
'v
Attachment
Addressees:
Byron M. Bunger (ANR-460)
John R. Cook (AN'R-460)
Allen C.B. Richardson (ANR-460)
Chris B. Nelson (ANR-461)
Luis R. Garcia (ANH-A60)
BAB Staff
EPA Fom 1370-4 (R... 6.771
-------
CAIRD CODE AND THE TERMS USED IN ITS LIFE TABLE
I. CAIRD: Cohort Analysis of Increased Risks of Death
II. Application: To estimate the number of induced cancer deaths resulting
from radiation exposure to an initial population of
100,000 individuals (Cohort)
III. Risk Models: (1) absolute
(2) relative
IV. Population: (1) general (total) population
(2) Male population
(3) Female population
V. Cohort used in code:
(1) Single cohort—
A cohort of 100,000 followed from first exposure (or
from age 0 in some cases) until the last reported
age interval, 109-110.
* (2) A population generated by having 100,000 newborns each
year and constant age-specific death rates throughout
lives *6f the members; i.e., a stationary population with
constant age distribution totaling 7,066,295 persons
VI
Definition
Age interval under consideration
Reference probability of death during
age interval (not including that
caused by radiation)
(3) IXR ' Probability of death due to radiation only
(A) TQXR Total probability of death = TQX + IXR
(5) LXR Number alive at the beginning of age
interval •* number of survivors from
last age Interval.
LXR(x -I- 1) - LXR(x) - DXR(x) (See (6))
(6) DXR Total number of deaths in the age
interval. DXR(x) - TQXR(x) x LXR(x)
(7) TLXR (a) Total years of life lived in the
age interval x to x + 1 by those
alive at the beginning of the interval
or (b) Average number of survivors in the
* Definitions marked (b) refer to situations when interpretations of CAIRD
data are made based on a stationary population.
-------
(8) TXR (a) Total years of life lived in the
age interval x to x 4- 1 and in all
subsequent age intervals by those
alive at the beginning of the age
interval.
or (b) Total number of persons in the
stationary population alive in the
indicated and all subsequent age
intervals.
TXR(x) - TLXR(x)+ TXR(x + 1)
(9) EXR Life expectancy of the Cohort =
TXR(x)
LXR(x)
(10) IXRLXR (a) For a single cohort—number of
premature deaths in the cohort in
the age interval resulting from
radiation exposure.
'J (b) For a stationary population—
number of premature deaths per
year for each specified age
interval due to radiation exposure
IXRLXR(x) = IXR(x) x LXR(x)
-------
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