EPA-650/4-74-048

NOVEMBER 1974
Environmental Monitoring Series

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Research reports of the Office of Research and Development, Environmental
Protection Agency, have been grouped into five series. These five broad categories
were established  to facilitate  further development and application of environmental
technology. Elimination of traditional grouping was consciously planned to
foster technology transfer and a maximum interface in related fields. The
five series  are:


          I.   Environmental  Health  Effects Research
          2.  Environmental Protection Technology
          3.  Ecological Research
          4.  Environmental Monitoring
          5.  Socioeconomic Environmental Studies

This report has been assigned to the ENVIRONMENTAL MONITORING series.
This series describes research conducted to develop new or improved methods
and instrumentation for the identification and quantification of environmental
pollutants at the lowest conceivably significant concentrations.  It also includes
studies to determine the ambient concentrations of pollutants in the environment
and/or the  variance of pollutants as a function of time or meteorological factors.

Copies of this  report are available  free of charge to Federal employees, current
contractors and grantees,  and nonprofit organizations - as supplies permit  -
from the Air Pollution Technical Information Center, Environmental  Protection
Agency, Research Triangle Park, North Carolina 27711; or, for a fee, from
the National Technical  Information  Service, Springfield, Virginia 22161.

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                                    EPA-650/4-74-048
AN  EVALUATION  OF ARSENITE PROCEDURE
    FOR  DETERMINATION OF  NITROGEN
          DIOXIDE IN  AMBIENT AIR
                        by

             Michael E. Beard and John H. Margeson
               Program Element No. 1HA327
                   ROAP No. 26AAF
         NATIONAL ENVIRONMENTAL RESEARCH CENTER
            OFFICE OF RESEARCH AND DEVELOPMENT
           U.S. ENVIRONMENTAL PROTECTION AGENCY
            RESEARCH TRIANGLE PARK. N. C. 27711

                   November 1974

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This report has been reviewed by the Environmental Protection Agency
and approved for publication.  Approval does not signify that the
contents necessarily reflect the views and policies of the Agency,
nor docs mention of trade names or commercial products constitute
endorsement or recommendation for use.
                          ACKNOWLEDGMENTS

        The authors wish to thank Mr. Robert G. Fuerst of Methods
   Standardization Branch, QAEML for his calibrations of the N0?
   permeation devices used in this study.  We would also like to
   thank Mr. John C. Puzak of Analytical Quality Control Branch,
   QAEML for his assistance in preparing regression equations and
   other statistical data.
                                  11

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                                CONTENTS
Section                                                                   Page
LIST OF TABLES	   iv
LIST OF FIGURES	   iv
  I.   INTRODUCTION  	    1
 II.   EXPERIMENTAL  	    2
III.   RESULTS AND DISCUSSION  	    6
 IV.   CONCLUSIONS	   21
  V.   FUTURE WORK	   21
 VI.   REFERENCES	   22
VII.   APPENDICES	   25
TECHNICAL REPORT DATA SHEET  	   40

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                             LIST OF TABLES

Table                                                                    Page

  1.   Effect of Nitric Oxide on Collection Efficiency	     9

  2.   Eight Combinations of Seven Factors Used to Test the
       Ruggedness of an Analytical Method 	    14

  3.   Arsenite Method Ruggedness Test - Format 	    18

  4.   Summary of Ruggedness Test Evaluation	    20
                             LIST OF FIGURES

  Figure                                                                 Page

     1     Percent Collection Efficiency of the Arsenite Method
          As a Function of N02 Concentration	   7

  A-l     Sampling Train	35

  A-2     Flowmeter	36
                                    IV

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        AN EVALUATION OF ARSENITE PROCEDURE FOR DETERMINATION



                 OF NITROGEN DIOXIDE  IN AMBIENT AIR
INTRODUCTION



     The Environmental Protection Agency (EPA) promulgated an



annual average of 100 micrograms-per-cubic meter (yg/m ) of nitrogen



dioxide (NOp) as a national primary ambient air quality standard.



The standard and a 24-hour reference method for determining compliance



were published in the Federal Register on April 30, 1971.^ '  The



reference method was later found to have a variable collection efficiency



and a positive interference from nitric oxide (NO).  ' ' '  These de-



ficiencies were considered serious and led EPA to search for new methods



for measuring NO- in ambient air.


                    (5)
     Christie et al.v ' reported a 95% collection efficiency of N00 in
                                                                  c


sodium hydroxide solutions containing 0.1% sodium arsenite.  This method



was investigated and adapted for field use by the Analytical Laboratory



Branch (ALB) of the Quality Assurance and Environmental Monitoring



Laboratory (QAEML) of EPA.  ALB's preliminary investigation showed the



arsenite (Christie) method to have a collection efficiency of 85%.  '



Thus, the arsenite method overcame the major deficiency of the original



reference method and was chosen as one of three candidate reference



methods published in the Federal Register as replacements for the



original reference method.  '



     Investigation of the arsenite method was continued in order to



establish its reliability.  This report contains the results of an
                                  1

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     evaluation  of the  mathod  made  by  the  Methods  Standardization Branch
     (MSB)  of  QAEML.  MSB  is  responsible for  standardizing methods  used
     in  determining compliance with the national ambient  air quality
     standards.   This standardization  process  includes:   1) a  review of
     the method  write-up  to  insure  that it is  clearly written  and technically
     accurate  and, 2) a laboratory  evaluation  to determine if  the method will
     perform according  to  the  specifications  of the write-up.  The  laboratory
     evaluation  may include  investigation  or  verification of such factors  as
     stoichiometry, collection efficiency, concentration  range or effect of
     interferents.  The extent of the  evaluation depends  on how well the method
     has been  developed and  documented.
          If a method proves  to  be  reliable after  MSB's evaluation, it can be
     subjected to a collaborative test designed to determine its precision
     (repeatability and reproducibility)  and  its accuracy (bias).   The colla-
     borative  test is the final  phase  of  the  standardization process and is
     a measure of the performance of the method in actual use.
II.   EXPERIMENTAL
     A.   General
              The method used for the  preliminary  phase  of  this  evaluation
     is  described in the Federal Register; '   The  information  gained in  the
     preliminary evaluation  was  used to  modify the original method  write-up.
     The modified procedure  was  used as  the basis  for the final  evaluation
     and is given in Appendix A.  Basically,  the method  consists of drawing
     ambient air  through a tube having a restricted  orifice immersed in  50 ml

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of a solution containing 0.1 N NaOH and 0.1% w/w sodium arsenite.  The
NOo in the ambient air is converted to nitrite ion.   The concentration
of nitrite ion is determined colorimetrically by formation of a purple
azo-dye.
B.   Sampling
          Samples were collected in quintuplicate by attaching 5
sampling tubes to a common manifold.  The flow rate for each tube was
measured before and after sample collection as directed in the method.
The total flow rate into the common manifold was also measured immediate-
ly before and after sampling and was compared with the sum of the in-
dividual flows to insure that there were no leaks in the system.  Samples
with a final flow more than 10% different from the initial flow were re-
jected.
C.   Flow Control
          The samples were collected at a rate of approximately 200cm /min
by using a 27 gauge hypodermic needle as a critical orifice as suggested
by the method.  A Gast Model 0211 oil-less vacuum pump was used to main-
tain a pressure drop across the orifice of approximately 0.6-0.7 atmos-
pheres.  The total sampling time ranged from 20 to 24-hours.
D.   Analysis
          After sampling was completed, the tubes were disconnected from
the manifold.  Water lost by evaporation during the sampling was replaced
and an aliquot of the sample was analyzed as described in the method.  A
Beckman Model "B" Spectrophotometer was used for the absorbance measure-
ments.

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  E.    Test Atmosphere Generation


       1.    Nitrogen Dioxide


                 Test atmospheres containing known amounts of NCL were


  generated by diluting the effluent from a gravimetrically calibrated


  NCL permeation device with various measured amounts of purified air.
                                                          (0\
  This procedure has been described by O'Keefe and Ortman,  ' and


  Scaringelli  ejt al_.  '   '  The permeation device was made by the Micro-


  chemical  Analysis Section of the National Bureau of Standards (NBS)


  and was  calibrated frequently at intervals between sampling periods.


  The stability of permeation rates from these devices with respect to


  time has  been well established.^  '


                 The temperature of the device was controlled by a water


  jacketed condenser, which was maintained at 25.0 j^0.1°C by a Forma  Temp,


  Jr. constant temperature bath.  The NCL was flushed from the jacket  by a

                3
  flow of 100 cm /min dry N,,.  The permeation rate for the device was


  1.184 j^O.OOl yg/min.  (Based  on  66 weighings).


                 Purified air was obtained by passing compressed (House)


  air through silica gel for drying, treating with ozone to convert any NO


  to N02,  and finally by passing through activated charcoal (6-A mesh),


  molecular sieve (6-16 mesh, type 4A), and silica gel (6-16 mesh) to


  remove any N02 and hydrocarbons.


       2.    Nitric Oxide


                 NO was introduced to the test atmospheres by means of a


  "T" connection in the N02 system.  A Kjeldahl trap following the "T"


  insured mixing of the NO with the test atmosphere.  A cylinder of NO in


  N~ was analyzed by gas-phase titration with 03 as described in the


4

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Federal Register '  and found to contain 100 ppm N0(122,700 yg/m )
                         o
and 3.0 ppm N02(5644 yg/m ).  Because of the N02 "impurity" in the
NO cylinder, it was necessary to calculate the exact N02 and NO con-
centrations using:
     P.R. yg/min  x  103L  +  Y_  5644 yg N02/m3  =  yg N02/m3
        X L/min        m3     X
and  Y L/min (122,700 yg NO/m3)  =  yg NO/m3
     X L/min
where
     P.R.  =  permeation rate of N02 device
       X   =  total dilution air flow rate
       Y   =  NO flow rate
     For test atmospheres containing a 4:1 ratio of NO:N02 approximately
80% of the N02 was from the permeation tube and 20% from the N02 impurity
in the NO cylinder.  For the atmospheres containing a 1:1 NO:N02 ratio
95% of the N02 was from the permeation tube and 5% from the NO cylinder.
     3.   Carbon Dioxide
               C02 was added to the test atmosphere by means of a "T"
connection, as in the addition of NO (see 2).  The C02 was supplied
from one of two cylinders containing 1060 ppm (XL in N2 and 99.9% C02.
Each cylinder was checked and found to be free of NO and N02 impurities
by means of a chemiluminescent N0-N02-N0  monitor.  The C02 concentration
in each  test atmosphere was calculated using:
         F    x C     =  C
          COp    C02        C02
         Ftotal

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     where  F      = flowrate  from COp cylinder




             total  = combined  flow rates  in manifold



            C™    = concentration of C09 in cylinder
             COp                        L.


            C      = concentration of COp added to  test atmosphere.



     No attempt was made to control  the COp concentration  in  the  purified  air.



     Thus, the final COp concentration was the ambient  concentration,  plus



     the amount added from the cylinder.



III.  RESULTS AND  DISCUSSION



     A.   Collection Efficiency



               The  preliminary evaluation of the arsenite  method  began with



     an investigation of the collection efficiency.   Establishing the  collection



     efficiency was essential  because the original  reference  method  had shown  a



     50% non-linear variation  in collection efficiency  over the  concentration


          (2)
     rangev  ' of  the method and the arsenite method was only  a modification



     of the original method.



               The  collection  efficiency  was determined by sampling  test



     atmospheres  containing 43.6? 77.7, 105, 106, 329,  449, 470,  644,  and



     743 yg NOp/m .  The samples were collected and analyzed  according to  the



     procedure described in the Federal Register: '   Collection  efficiencies



     (percent) were calculated by the ratio of NO,,  recovered  (as  nitrite ion)



     to N02 generated x 100 and are shown as a function of NO- concentration



     in Figure 1.  Data for this figure is found in Appendix  B.   The least



     squares regression equation for the  data is:



               %  CE  =  82.46  - 0.00085 (ygN02/m3)



     The intercept  of the equation (82.46) represents the  collection efficiency



     of the method  and the slope (-.00085) shows no significant  change in
       An  NOp-permeation  device with  a rate  of 0.723  pg/min was  used  to  obtain


       this  level.


   6

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   100











    95











    90






C
tu
u

I   85




u
Z   80
                    O

                o   a
                                                 o
                                                 o
                                                                    ©

                                                                    o
                                                                                                        o


                                                                                                        8
            o   o   o

                0   e
o

P
o
o
o
    75
    70
    65
    60
                                                                 8




                                                                 O
                                                                                           ©

                                                                                           o


                                                                                           8
                                                           % COLLECTION EFFICIENCY = 82.46 • 0.00085 (/ugN02/m3)
                  100
                                200
                                             300           400           500




                                                N02 CONCENTRATION, jjg/m3
                                                                                    600
700
                                                                                                               800
          Figure 1.  Percent collection efficiency of the arsenite method as a function of N02 concentration.

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collection efficiency over the concentration range examined.



           The arithmetic mean of the collection efficiencies obtained



from the data in Appendix B is 82.2% with a relative standard deviation



(RSD) of 4.5%.  This is similar to the variability of other impinger


                   (9)
collection systems.  '  More importantly, the data verifies that the



variable collection efficiency of the original  reference method has  indeed



been overcome by the arsenite modification.



     B.    Nitric Oxide Effect



                The next step in the evaluation of the arsenite method



was an investigation of the response of the method to nitric  oxide (NO).



The original reference method had shown an appreciable positive inter-


                (2 3 4)
ference from NO.   ' ' '  The mechanism by which the NC interfere is



believed to be described by the reaction



                        NO + N02 + 2"OH-> 2N02 + H20



In this reaction the NO interference depends on both the NO and N02  con-



centrations; therefore, it was necessary to sample test atmospheres  con-



taining various ratios of NO:N02 in order to 'evaluate their effect on



the method.

                                                                 3

            Test atmospheres containing approximately 100 ygNOp/m  and



NO:N02 ratios (w/w) of 0:1, 1:1 and 4:1 were generated and sampled accord-



ing to the method described in the Federal Register: '  Collection



efficiencies were calculated as in III.A. and are shown in Table 1.

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     Table 1.   Effect of Nitric  Oxide  on  Collection  Efficiency.
NO:N02*
w/w
0:1
0:1
1:1
1:1
4:1
4:1
Mean Collection
Efficiency
%
78.1
82.6
90.5
82.2
89.2
85.1
Standard
Deviation
%
2.7
1.3
1.0
1.5
1.4
1.0
*N02 concentration 103 to 106 ygN02/m3.

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               The atmospheres which contained only N(L (0:1)  gave
     collection efficiencies of 78.1% and 82.6% (average 80.4  +3.2) and
     were used as a basis for comparison to measure the effect of the atmo6.
     spheres containing NO.  The test atmospheres containing a 1:1 ratio
     gave collection efficiencies of 90.5% and 82.2% (average  86.4 +_5.9).
     By comparing the 1:1 values with the 0:1 values, it is difficult to
     draw any conclusions because of the variability of the data.
               The 4:1 ratios gave values of 89.2% and 85.1% (average 87.2  +
     2.9).  Comparing the base value (0:1) of 80.4 +_ 3.2 with  the 4:1 value
     of 87.2 +_ 2.9, the effect of the NO becomes significant.   However, the
     difference is small.
               Additional work is needed to define the actual  effect of NO
     in the arsenite method.  However, it is important to note that the effect
     of the NO in the arsenite method is not as severe as that of the original
                                                  (2}
     reference method indicated by Hauser and Shy.x '
          C.   Other Factors Evaluated
               1.  Orifice Diameter
                         The normal value for the diameter of the glass orifice
     in the bubbler was  originally 0.4 mm.  One lot of glass orifices supplied
     by a local glass blowing shop were examined and found to range from 0.4 mm
     to 0.9 mm.  No significant difference in collection efficiency was found
     using orifice diameters between 0.4 and 0.8 mm.  Therefore, the middle
     value and the range of orifices tested, 0.6 +_0.2 mm, was adopted in place
     of 0.4 mm.
10

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          Pressure drops across the glass orifice in the sampler



were between 10 and 16 mm Hg for the orifice diameters used.   These



pressure drops should have had no significant effect on the pressure



drop across the critical orifice used for flow control.



          2.  Analytical System



                   The diazotation-coupling reaction used to detect



nitrite in this analysis is well documented in the literature.  How-



ever, certain parameters in the analysis were deemed worthy of investi-



gation to insure that the arsenite modification had not affected them.



                   The optimum pH and time for color development were



investigated and found to be 2.0 and 10 minutes, respectively.  The



color was stable for at least 30 minutes after development.



                   The stability of a collected N02 sample was in-



vestigated by analyzing a sample containing approximately 0.55 yg NO^/ml



(equivalent to 100 yg NO^/m ) at 0, 1, 4 and 41 days after collected.



No significant change in concentration was found.



                   Since the pH, time for color development, and sample



stability were found to be as described by the method and related



litereature, no changes in the original specifications were necessary.



     D.  Preliminary Assessment



              At this point in the investigation, a preliminary assess-



ment of the arsenite method was made.  The constant collection efficiency



and lower response to NO overcame the most serious problems associated



with the original reference method.  Therefore, it was decided that a
                                                                      11

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   further, more detailed, evaluation was warranted.  The original
   method write-up, used in the preliminary experiments, was edited
   and modified to its present form (Appendix A) incorporating the in-
   formation gained in the preliminary studies.  This version of the
   method was then subjected to further investigation to determine the
   effect of various parameters which had not previously been evaluated.
        E.   Ruggedness Testing
             1.  Design
                      The second phase of the evaluation involved a test
   designed to determine the sensitivity of important operational para-
   meters to slight changes similar to those encountered in normal use.
   This type of evaluation is called ruggedness testing.  It is accomplish-
   ed by conducting a series of controlled experiments  in which selected
   parameters are  varied at two levels: the nominal  level stated in the
   method write-up and a challenging level.  The results obtained using the
   nominal  procedure are compared with the results  obtained using the
   variation  in order to determine the effect of the variable.  Parameters
   which  significantly effect the method response can then be more carefully
   controlled, thereby improving the method.
                      An  ingenious scheme for determining the individual
   effects  of  variations  in several parameters  with a minimum number of
   experiments has been  described by Youden.^ *'  Seven d  parameters  are
     a Schemes  for examining the effect of a  larger  or  smaller  number  of
                                (13)
       parameters  are available/  '
12

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chosen for testing and their nominal  values are denoted by A,  B,
C, D, E, F, and G.  A challenging value for these parameters is then
selected and denoted by a, b, c, d, e, f, and g.  A series of eight
experiments are then conducted using various combinations of either
nominal or challenging values for each variable.  The format for
these experiments is shown in Table 2.
               Each of the eight experiments produces a result, de-
noted as S, T, U, V, W, X, Y, and Z.   Examination of the format in
Table 2 reveals that by summing the group of experiment results in
which a given nominal value was involved and subtracting from it the
sum of the group of results in which the corresponding challenging
value was involved, the effect of all other variables are canceled.
If the grouped results are divided by the number in each group, the
above subtraction will yield the average effect or difference between
the nominal and challenging conditions.
               For example, the average effect of variable A is cal-
culated using
               A-a  =  S+T+U+V  -  VI+X+Y+Z
                          4           4
A complete set of equations for calculating the effect of A-a, B-b, etc.
are given in Appendix C.
               It should be noted that the results of the ruggedness
test will not completely describe the effect of varying a given para-
meter.  The results only show the effect of the range of variation used
                                                                     13

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      Table 2.  Eight Combinations of Seven Factors Used to Test the
                Ruggedness of an Analytical Method
                              Determination Number
Factor
Value

A or a
B or b
C or c
D or d
E or e
F or f
G or g
Observed
Result

1

A
B
C
D
E
F
G
S


2

A
.B
c
D
e
f
g
T


3

A
b
C
d
E
f
g
U


4

A
b
c
d
e
F
G
V


5

a
B
C
d
e
F
g
W


6

a
B
c
d
E
f
G
X


7

a
b
C
D
e
f
G
Y


8

a
b
c
D
E
F
g
Z

14

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in the experiment.   If the effect is shown by the test to be signi-
ficant, a series of tests controlling various levels  of that para-
meter are then necessary to describe the exact relationship.
          2.   Selection of Parameters
                   Several parameters were considered to be subject
to variation and possibly critical to the performance of the arsenite
method.
              a.  Concentration
                       The effect of various concentrations of N0?  on
the arsenite method had been previously evaluated in the determination
of the collection efficiency.  However, the effect of other variables in
association with the NCL concentration was not known.  Therefore, NCL
                                    3
concentrations of 65 and 700 pgNO/m  were chosen to cover the range of
the method.
              b.  Temperature
                       Methods used in the field are always subjected
to extremes of temperature that can affect the collection efficiency of
the method.  The sampling devices used in most 1^ networks are equipped
with warming devices to eliminate the cold or near freezing temperatures.
Therefore, a temperature of 25°C was selected for the nominal condition and
35°C was chosen for the challenge.
              c.  Orifice Size
                       Orifice size can affect collection efficiency
by controlling the surface area of the bubbles produced in the solution.
A test of  the effect of an orifice diameter outside the prescribed 0.6 +_
0.2 mm was made by using 0.6 mm for the nominal value and 1.0mm for the
                                                                        15

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    challenging value.
                   d.  Flow Rate
                            The method requires a flow rate of 180 to
    220 cm /min.  Since the collection efficiency of a method can be
    affected by the rate of delivery of the sample to the absorbing solution,
    it was decided to examine the effect of flow rates.  The nominal and
                                                                3
    challenging flows selected were 180 to 220 and 310 to 340 cm /min,
    respectively.
                   e.  Sodium Arsenite Concentration
                            The original work by Christie determined  the
    optimum amount of NaAs02 for N02 absorption by adding gaseous N02 to
    solutions containing various amounts of NaAs02 and then shaking the
    mixture.  '  Since this experiment does not duplicate the dynamic
    solution process of the sampling system, it was decided to examine
    NaAsOp concentration.  The nominal value was l.Og/L, as described in
    the method,and the challenging value was set at 0.8g/L.
                   f.  Carbon Dioxide Concentration
                            Merryman reported a decrease in collection
    efficiency of an arsenite-type procedure with a COp concentration of
    2000 ppm/ '  However, he showed no effect with C02 near the ambient
    level of 300 ppm.  Thus, a test to determine the effect of C02 concen-
    trations slightly above the ambient level was conducted.  The nominal
    value for C02 was the existing ambient concentration.  The challenging
    concentration used was the nominal value, plus 300 ppm.
16

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               g.  System Blank
                        The format described by Youden provides for
evaluation of seven variables.   If the performance of the method is well
documented and understood, a complete set of seven variables may be
tested.  When the method does not meet these requirements, it is
advisable to replace one of the variables with a system blank.   It
should be noted here that the system blank is unlike the customary
blank in which the concentration of NC^ would be zero.  The system
blank is merely a mathematical  balance of all the variable conditions
                  (12)
in the experiment.   '  If this experiment yields a low difference we
may conclude that there were no uncontrolled factors which are  critical
to the performance of the method.  Thus, a system blank was chosen for
the seventh and final experiment in the ruggedness test.
          3.  Conducting the Ruggedness Test
              a.  Test Plan and Results
                       The parameters chosen for the ruggedness test
were incorporated into the format previously described and are  shown in
Table 3.  The experiments were conducted in random order (6, 1, 3, 7,
8, 2, 5, and 4) and the individual and average results for each
determination are given in Appendix D.  It should be noted that the
results are expressed in per cent.  This was calculated by dividing the
concentration found by the concentration of NCL generated.  This
normalization of the results was necessary before the effect of the
different parameters could be determined because, the method is obviously
                                                                        17

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00
                                     Table  3.   Arsenite  Method  Ruggedness  Test Format
                                                                   Determination  Number
Factor Value

N0? Concentration
A = 65ug/m3 a = 700ug/m3
Absorber Temperature
B = 25°C b = 35°C
Orifice Size
C = 0 . 6mm c = 1 . Omm
Flow Rate
D = 200cm /mi n d = 300cm /mi n
Sodium Arsenite Cone.
E = l.Og/L e = 0.8g/L
COp Concentration
F = Ambient f = Ambient+300
System Blank
G = g, No variation
Observed Resul t
1
65y.g/m
25°C

0.6mm

200cm /mi n
l.Og/L

Ambient
-

S
2
65
25

1.0

200
0.8

Amb. + 300
-

T
3
65
35

0.6

300
1.0

Amb. +300
-

U
4
65
35

1.0

300
0.8

Ambient
-

V
5
700
25

0.6

300
0.8

Ambient
_

W
6
700
25

1.0

300
1.0

Amb. +300
_

X
1_
700
35

0.6

200
0.8

Amb. +300
_

Y
8
700
35

1.0

200
1.0

Ambient
_

Z

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sensitive to NOp concentration.
                    The results  in Appendix D were substituted into
the equations of Appendix C and the effect of each parameter was
calculated.  The net results are shown ranked in order of absolute
magnitude in Table 4.
               b.  Results
                   1.  Carbon Dioxide Concentration
                            The most significant effect on the arsenite
method was due to the C02 concentration.  The positive value of 18.3%
indicates that the recovery of NCL is significantly reduced by the
presence of an additional 300 ppm COo (over ambient) in the air sample.
Thus, C02 is a negative interferent in the method.
                   2.  Flow Rate
                            The recovery of NOp was apparently reduced
                                3                          3
by 14.4% by flow rates of 300 cm /min instead of the 200 cm /min required
by the method.  However, this effect may be related to the increased COp
intake at the higher flow rate rather than the flow rate alone.
                   3.  Orifice Size
                            The negative 2.6% value obtained for this
variable indicates the 1.0mm orifice has a slightly greater recovery
than the 0.6mm orifice.  The preliminary evaluation of this variable
indicated that increasing the orifice size had the reverse of this
result, although the magnitude did not appear to be significant.  The
small magnitude of this result and the possible contradiction between
                                                                      19

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         Table 4.  Summary of Ruggedness Test Evaluation.

  Rank           Factors                                  Difference
     1.   C(L Concentration                                  18.3
         Ambient  vs Ambient +  300
    2.    Flow  Rate                                          14.4
               3               3
        ^200cm /min  vs 'vSnOcm /min

    3.    Orifice Size                                   (-)   2.6
          0.6mm vs 1.Omm
    4.   N02 Concentration                              (-)   1.9
         65ug/m3  vs  700  Mg/m3
     5.    NaAsOp  Concentration                           (-)   1.5
          l.Og/L  vs  0.8g/L

     6.    Temperature                                         1.2
          25°C  vs  35°C

     7.    Experiment Blank                                    1.1
20

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     the  preliminary  evaluation  and  the  ruggedness  test  are  considered
     to be  of no  consequence.
                         4.   Other Parameters
                                  The  values  obtained  for the  N0?  concen-
     tration, NaAs02  concentration,  temperature,  and system  blank  were  1.9,
     -1.5,  1.2 and 1.1%,  respectively.   These  values indicate  that the  effects
     of  these variations  were insignificant.   The small  difference obtained
     for  the system blank indicates  that there were no critical  factors uncon-
     trolled in the test.
IV.   CONCLUSIONS
          The arsenite method has a constant-high collection efficiency over
     the  entire range of the method.  The method  is insensitive  to normal
     variations in: orifice bubbler diameter,  temperature of the absorbing
     solution during  sampling, and concentration  of sodium arsenite.   However,
     NO  and C02 are positive and negative interferents,  respectively;  sample
     flow rate may also be a variable  affecting the method response and should
     be  closely controlled.
          Before an assessment can be  made as to  the  utility of  the arsenite
     method for measuring N02 in ambient air,  the effect of the  above  inter-
     ferents, and flow rate, on the method response needs to be  quantiated.
     (Present-incomplete data indicate that the interference from NO is small,
     approximately 10%).
V.   FUTURE WORK
          Future work will.involve determining if the  reduced  method response
     attributed to flow  rate, as a result of the ruggedness test, was  caused
     by increasing the N02 sampling rate and/or COn consumption.
                                                                             21

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          Additional  combinations  of NO  plus  N(L  and C(L  plus  NCL will



     be sampled to quantify the effect of these interferents on  the method



     response.   The experiments will be designed so that equations  can be



     developed  from the data that  will allow calculation of the  effect of



     NO or C0?  concentration (in combination with  N0?) on the method response.



          This  information will allow a judgment to be made as to the practical



     magnitude  of the interferences and consequently the utility of the method



     for making NOp measurements.   If both the interferences are minimal, the



     method could be used as is and the fact documented with the equations.



     If either  of the interferences is too high, further development of the



     method to  eliminate the interference(s) would be recommended.



VI.   REFERENCES



     1.  Federal Register, 36, April 30, 1971, National Primary  and Secondary



         Ambient Air Quality Standards, p. 8186-8187, Appendix F, p. 8199-8200.



     2.  Mauser, T. R. and Shy, C. M., Environmental Science and Technology, 6_,



         10, 1972, p. 890-894.



     3.  Heuss, J. M., Nebel, G. J., and Colucci,  J. M., Journal of the Air



         Pollution Control Association, 21_, 9, 1971, p. 535-548.



     4.  Merryman, E. L., Spicer,  C. W. and Levy,  A., Environmental Science and



         Technology, 7, 11, 1973,  p. 1056-1059.



     5.  Christie, A. A., Lidzey,  R. G., and Radford, D. W. F.,  Field Methods for"



         the Determination of Nitrogen Dioxide in Air, Analyst,  95, May 1970,



         p. 519-524.




     6.  Wheeler, V. A., Knapp, K. T., and Thompson, R. J., "Aqueous Absorbing



         Solutions for Ambient Monitoring of Nitrogen Dioxide,"  presented at




 22

-------
     165th  National  Meeting  American  Chemical  Society,  April  1973.
 7.   Federal  Register,  3JS,  110,  June  8,  1973,  Reference Method  for
     Determination  of Nitrogen  Dioxide,  p.  15174-15176.
 8.   O'Keefe, A.  E.  and Ortman,  G.  C.,  "Primary Standards  for Trace  Gas
     Analysis," Analytical  Chemistry,  38,  p.  760,  (1966).  .
 9.   Scaringelli, F.  P., Frey,  S.  A.  and Saltzman,  B.  E.,  "Evaluation of
     Teflon Permeation Tubes for Use  with  Sulfur Dioxide," Journal  of the
     American Industrial Hygiene Association,  28,  p.  260,  (1967).
10.   Scaringelli, F.  P., O'Keefe,  A.  E., Rosenburg, E., and Bell,  0.  P.,
     "Preparation of Known  Concentrations  of Gases  and Vapors with  Per-
     meation  Devices Calibrated Gravimetrically,"  Analytical  Chemistry,
     42_, 8, p. 871,  (1970).
11.   Rook,  H. L., Fuerst, R. G., and  Margeson, J.  H., Progress  Report: EPA-
     NBS Study to Determine the Feasibility of Using NOp Permeation Devices
     as Standards,  December 1972 - January 1973.
12.   Youden,  W. J., "Statistical Techniques for Collaborative Tests," 1967,
     p. 29-32, Association  of Official Analytical  Chemists, Washington,
     D. C.  20044.  Price $2.00.
13.   Plackett, R. L., and Burman, J.  P., "The Design of Optimum Multi-
     factorial Experiments," Biometrika, 3_3, 305 (1946).
                                                                         23

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VII.  Appendices
      A.   Tentative Method for the Determination of Nitrogen

          Dioxide in the Atmosphere (Sodium Arsenite Procedure).*

      B.  Collection Efficiency vs Concentration.

      C.  Equations for Evaluation of the Ruggedness Test.

      D.  Arsenite Method Ruggedness Test Data.
  *A tentative method is one that has been carefully drafted from
   available experimental information, reviewed editorially within
   the Methods Standardization Branch, and undergone extensive
   laboratory evaluation.  The method is still under investigation
   and, therefore, is subject to revision.
                            25

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  APPENDIX A.   TENTATIVE METHOD FOR THE DETERMINATION OF NITROGEN  DIOXIDE
               IN THE  ATMOSPHERE (SODIUM ARSENITE PROCEDURE)
1.   Principle and Applicability

     1.1    Nitrogen dioxide is collected by bubbling air through a sodium

hydroxide-sodium arsenite  solution to form a stable solution of sodium
     A
nitrite.  The nitrite ion produced during sampling is reacted with phos-

phoric acid, sul fenilar.ide, and N-l-(naphthyl)ethylenediamine dihydro-

chlorids to form an azo dye and then determined colorimetrically.

     1.2    The method is applicable to collection of 24-hour samples in

the field and subsequent analysis in the laboratory.

2.   Range and Sensitivity

     2.1    The range of the analysis is 0.04 to 2.0 yg N0"/ml.  Beer's lav/

is obeyed through this range (0 to 1.0 absorbance units).  With 50 ml

absorbing reagent and a sampling rate of 200 cm /min for 24-hours, the
  nge of the net hod is 20 to 750 ;;g/m  (0.01  to 0.4 ppm) nitrogen dioxide.'

     2.2    A concentration of 0.04-tS NO-Vml-v;i 11 produce-en-absorbance of

approximately 0.02 with 1-cm cells.

3.   Interferences

     3.1    Nitric oxide is a positive interferent.   The presence of NO can
                                                         2
increase the NO- response by 5 to 15?. of the N02 sampled.

     3.2   -.The interference of sulfur dioxide is eliminated by converting

it to sulfate ion \vith hydrogen peroxide before analysis.

4.   Precision, Accuracy and Stability

     4.1    The relative standard deviations  for sampling N02 concentrations

of 78, 105 and 329 ug/m  are 3, 4 and 22, respectively.
                                                                           27

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     4.2    No accuracy data are available.
     4.3    Collected samples are stable for at least 6 weeks.
5.   Apparatus
     5.1    Sampling.  A diagram of a suggested sampling apparatus is
shown in Figure 1.
     5.1.1  Probe.  Teflon, polypropylene, or glass tube with a polypropylene
or glass funnel at the end.
     5.1.2  Absorption Tube.  Polypropylene tubes 164 x 32 mm, equipped
with polypropylene two-port closures.  Rubber stoppers cause high and vary-
ing blank values and should not be used.  A' glass-tube restricted orifice
is used to disperse the gas.  The tube, approximately 8 mm O.D.-6 mm I.D.,
should be 152 rrm long with the end drawn out to 0.3 » 0.8 mm I.Dia'The tube
should be positioned so as to allow a clearance of 6 mm from the bottom of
the absorber.
     5.1.3  Moisture Trap.  Polypropylene tube-equipped with two-port
closure.  The entrance port of the closure is fitted with tubing that extends
to the bottom of the trap.  The unit is loosely packed with glass wool to
prevent moisture entrainment.
     5.1.4  Membrane Filter.  Of 0.8 to 2.0 microns porosity.
     5.1.5  Flow Control Device.  Any device capable of maintaining i. con-
stant flow through the sampling solution between 180-220 cm/min.  A typical
flow control  device is a 27 gauge hypodermic needle,  three-eights inch long.
(Most 27 gouge needles will give flow rates in this range.)  The device
used should be protected from particulate matter.  A membrane filter is

^a'This  specification  was  modified after the completion of our  study by addition-
   al  information  obtained from other investigators.  '
28

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•.suggested.  Changs filter after collecting 10 samples.
 .»
 •      5.1.6  Air Pump.  Capable of maintaining a  pressure  differential

  of at 'least 0.6-0.7 of an atmosphere across the  flow  control  device.

,  This value includes the minimum useful differential,  0.53  atmospheres,

 'plus a safety factor to allow for variations in  atmospheric pressure.

 !;     5.1.7  Calibration Equipment. - Flowmeter for measuring airflows  up

 •('to 275 cm /min. within + 2%, stopwatch, and a precision wet test meter
 ,'-•                 •      ™~

••;'• (1 liter/revolution).
 ' i
.•••••     5.2    Analysis

       5.2.1  Voluretric Flasks.  50, 100, 200, 250,  500, 1,000 ml.

 ;     5.2.2  Graduated Cylinder.  1,000 ml.
 \;
..-.•;     5.2.3  Pipets.  1, 2, 5, 10, 15 ml volumetric; 2 ml, graduated in
 11'                               '
-.ST'T^r-"1 •?*•*--*-••~^-
 ., I/ lo fill ifi (.cTva ii .

•  •     5.2.4  Test Tubes, approximately 20 x 150 mm.

       5.2.5  Spectrophotoreter.  Capable of measuring  absorbance  at 540 nm.
 ,>

 :','6.   Reagents

       6.1    Sampling

*•:      6.1.1  Sodium Hydroxide.  ACS Reagent Grade.

       6.1.2  Sodium Arsenite.   ACS Reagent Grade.

       6.1.3  Absorbing Reagent.  Dissolve 4.0 g sodium hydroxide  in distill'
 t
 ;
-------
     6.2.2  N-(l-Naphthyl)-ethylenediamine dihydrochloride (NEDA).   Best
grade available.
   , 6.2.3  Hydrogen Peroxide.   ACS Reagent Grade,  30».
     6.2.4  ScdiuT, Nitrite.   Assay of 972 NaN02  or  greater.
     6.2.5  Phosphoric Acid.   ACS Reagent Grade, 85%.
     6.2.6  Sulfanilamide Solution.  Dissolve 20 g  sulfanilamide in 700
ml distilled water.   Add, with  mixing, 50 ml  concentrated  phosphoric acid and
dilute to 1,000 ml.   This solution is stable  for one  month,  if refrigerated.
     6.2.7  NEDA Solution.  Dissolve 0.5 g of NEDA  in 500  ml  of distilled
water.  This solution is stable for one month, if refrigerated and  protected
from light.
     6.2.8  Hydrogen Peroxide Solution.  Dilute  0.2 ml  of  30/J hydrogen
peroxide to 250 ml with distilled water.  This solution  may  be used for cnc
month, if protected from light  and refrigerated.
     6.2.9  Standard Nitrite  Solution.  Dissolve sufficient  desiccated
sodium nitrite and dilute with  distilled water to 1,000  ml so that  a
solution containing 1,000 ug  NOl/ml is obtained.  The  amount of NaNO- to
use is calculated as follows:
          --                  r     1.500  v 100
                               =  —5—
    G =  Amount of NoNOp grams.
1.500 =  Gravin-etric factor  in  converting NOp into  NaNOp.
    A =  Assay, percent.
30

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7.   Procedure


     7.1    Sampling.   Assemble the sampling apparatus as shown in


FigureAl.  Components  upstream from the absorption tube may be connected,


where required, with teflon or polypropylene tubing;  glass tubing with


dry ball joints; or glass tubing with butt-to-butt joints with tygon,


teflon or polypropylene.   Add exactly 50 ml  of absorbing reagent to the


calibrated absorption  tube (8.1.3).  Disconnect funnel, insert calibrated


flowmeter, and treasure flov/ before sampling.  If flow rate before sampling


is not betv:een 180 and 220 cm /min, replace  the flow control device and/or


check the system for leaks.  Start sampling  only after obtaining an initial


flow rate in this ranga.   Sample for 24 hours and measure the flow after


the sampling period.


     7.2    Analysis.   Replace "any water lest by evaporation d-jring sampling


by adding distilled water up to the calibration mark  on the absorption tube.
                                i

Pipet 10 ml  of the collected sample into a test tube.   Pipet in 1 ml  hydrogen


peroxide solution, 10  ml  sul fanilamide solution, and  1.4 ml NEDA solution


with thorough mixing after the addition of each reagent.  Prepare a blank in


the same manner'using  10  ml of unexposed absorbing reagent.  After a 10-minute


color-doveloprrent interval, measure the absorbance at 540 nm against the blank,


Read pg NOl/ml from the calibration curve (Section 8.2).  Samples with an


absorbance greater than 1.0 must be reanalyzed after  diluting an aliquot


(less than 10 ml) of the  collected sample with unexposed absorbing reagent.
                                                                             31

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 8.   Calibration and Efficiencies
     8.1    Sampling
                                                 /-
     8.1.1  Calibration of Flcwmeter.  (See Figure 2).  Using a wet test
                                                          3
 meter  and a stopwatch, determine the rates of air flow (cm /min) through
 the  flcwmeter at a minimum of four different ball positions.  Plot ball
 positions versus flcv.1 rates.
     8.1.2  Flow Control Device.  The flow control device results in a
 constant rate of air flow through the absorbing solution.  The flow rate
 is determined in Section 7.1.
     8.1.3  Calibration of Absorption Tube.  Calibrate the polypropylene
 absorption tube (Section 5.1.1) by first pipeting in 50 ml of water or
 absorb"! r.g ;c-c;r,t.  Scribe the level of the meniscus with a sharp object,
•go over the' area with a felt-tip marking pan, and rub off the excess.
     8.2    Calibration Curve.  Dilute 5.0 rn,l of the 1,000 yg NO^/ml
 solution to 200 ml with absorbing reagent.  This solution contains 25 yg
 NO^/ml.  Pipot 1, 1, 2, 15, and 20 ml of the 25 yg N0"/ml solution into 100-,
 50-, 50-, 250-, and 250- ml volumetric flasks and dilute to the mark with
 absorbing recrent.  The solutions contain 0.25, 0.50, 1.00, 1.50 and 2.00
 pg NO^/nl, respectively.  Run standards as instructed in 7.2, including
 the blank.  Plot absorbance vs.  ug NOl/ml.  A straight line with a slope
 of 0.13 j_ 0.02 absorbance units/ug N0"/ml, passing through the origin,
 should be obtained.
32

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     8.3    Efficiencies.  An overall average efficiency of 82% was
obtained over the range of 40 to 750 wg/m  NOp-
9.   Calculation
     9.1    Sair.pl ing
     9.1.1  Calculate volu~.-2 of air sampled.
                  F   + F          '
                            X T X 10
   V   =  Volume of air sampled, m .
   F,  =  Measured flow rate before sampling, cm /min.
                                               3
   F?  =  Measured flow rate after sampling,-cm /min.
   T   =  Time of sampling, min.
  -6                      3     3
10"    =  Conversion of on  to m .
    .9.1.2  Uncorrected Volume.  The volume of air sampled is not corrected
to S.T.P. because of the uncertainty associated with 24-hour average
temperature and pressure values.
     9.2    Calculate the concentration of nitrogen dioxide as yg NO^/m
using:
            pg N02/m3  =  (ug Np;/rr.l) X 50
                             V X 0.82
•  50  =  Volurr.e of absorbing reagent used in sampling, ml.
   V  c  Voluirc of air sair.pled, m .
0.82  - . Collection efficiency.
     9.2.1  If desired, concentration of nitrogen dioxide may be calculated
as p.p.m. fiOp using:
                      p.p.m. H02  =  (ug Hb2/m3)  X 5.32  X 10"4

                                                                          33

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 10.    References



 1.     Christie,A. A. e_t al_.  "Field Methods  for  the Determination  of



       Nitrogen Dioxide in Air."  Analyst 95. 519-524  (1970).



 2.     Unpublished results, Environmental Protection Agency,  Research



       Triangle Park, N. C. 27711.



 3.     Merryman, E. L. e_t a]_.   "Effects of NO, C02> CH4>  H20  and  Sodium



       Arscnite on N'Op Analysis."  Presented  at the Second  Conference on



       Natural Gas Research and Technology in Atlanta,  Georgia  on June 5,



       1972.



 4.     Jacobs, M. B. and Hochheiser, S., "Continuous Sampling and Ultramicro-



       determination of Nitrogen Dioxide in Air,"  Anal.  Chem.  30,   426



       (1953).      -



 5.     Lodge, J. P. et_ aj_.  "The Use of Hypodermic Needles  as Critical



       Orifices in Air Sampling."  J.A.P.C.A., 1_6., 197-200  (1966).
34

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               BUBBLER
                                                      TRAP
                                                     Figure A-1. Sampling train.
CO
en

-------
CO
CT>
    OPEN
     TO
  ATMOSPHERE
                                                          RATE CONTROL VALVE
                                                                                      PUMP
                                    FLOWMETER
                                       Figure A-2. Flowmeter.

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Appendix B.  Collection Efficiency vs Concentration.
N0? Generated      N09 Found     Collection     Mean     Standard
                     *           ™ •-         ,       Deviation
   43.6               35.8           82.1        84.1       2.3
   77.7               63.7           82.0        82.5       2.9
   105                83.3           79.3        78.1       2.7
   106                87.8           82.8        82.6       1.3
N09 Found
£
3
37.3
37.0
35.8
35.4
37.7
61.8
62.9
63.7
64.6
67.7
77.5
84.8
83.3
83.1
81.8
88.1
89.3
87.8
85.7
87.0
280
280
273
284
267
366
367
351
362
362
429
428
417
511
502
486
512
490
632
616
601
613
617
Collection
Efficiency
85.6
84.9
82.1
81.2
86.5
79.5
81.0
82.0
83.1
87.1
73.8
80.8
79.3
79.1
77.9
83.1
84.2
82.8
80.8
82.1
85.1
85.1
83.0
86.3
81.2
81.5
81.7
78.2
80.6
80.6
91.3
91.1
88.7
79.3
78.0
75.5
79.5
76.1
85.1
82.9
80.9
82.5
83.0
   329                 273           83.0        84.1       2.0
   449                 351           78.2        80.5       1.4
   470                 428           91.1        90.4       1.4
   644                 486           75.5        77.7       1.8
   743                 601           80.9        82.9       1.5


                                                                     37

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    Appendix C.  Equations for Evaluation of  the  Ruggedness  Test.

    1.  A-a  =  S + T + U + V  -  VI + X + Y + Z
                      4                 4
    2.  B-b  =  S + T + M + X  -  U + V + Y + Z
                      4                 4
    3.  C-c  =  S + U + VI + Y  -  T + V + X + Z
                      4                 4
    4.  D-d  =  S + T + Y + Z  -  U + V + W + X
                      4                 4
    5.  E-e  =  S + U + X + Z  -  T + V + VI + Y
                      4                 4
    6.  F-f  =  S +-V+'Vr+ Z  -  T + U + X + Y
                      4                 4
    7.  G-g  =  S + V + X + Y  -  T + U + VI'+ Z
                      4                 4
•\ .'••
 38

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     Appendix D.  Arsenite Method Ruggedness Test Data.
Determination No.  NO, Generated   NCL Found   % Response
                                   yg/m3
                      Mean   Observed Result
                             Designation
                        65.9
                        66.6
                        66.4
                        66.3
                        736
                        735
                        722
                        741
61.8
62.8
59.0
63.2
58.4
48.4
52.0
52.9
52.0
52.6
                                                   93.8
                                      36.
                                      39.
38.0
39.3
39.0
                                      53.
                                      54.
54.1
                                      53.
                                      53.
 617
:593
 596
 595
 560
 485
 498
 478
 473
 443
 541
 551
 551
 549
 576
 696
 707
 698
 696
 716
95.
89.
95.
72.7
78.1
79.4
78.1
79.0
54.5
59.5
57.2
59.2
58.7

80.7
82.4
81.6
80.7
80.2

83.8
80.6
81.0
80.8
76.1

66.0
67.8
65.0
                                                   64.
                                                   60,
                                                   74.9
  ,3
  .3
76.
76.
76.0
79.8
93.9
95.4
94.2
93.9
96.6
          92.6
          77.5
          57.8
         .81.1
          80.5
          64.7
76.7
          94.8
                                                                                 39

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                                TECHNICAL REPORT DATA
                          (Please read Instructions on the reverse before completing)
1. REPORT NO.
  EPA-650/4-74-048
                                                       3. RECIPIENT'S ACCESSION-NO.
4..TITLE AND SUBTITLE
                                                       5. REPORT DATE
 An  Evaluation of Arsenit« Procedure for
 Determination  of  Nitrogen  Dioxide in Ambient Air
               November  1974
            6. PERFORMING ORGANIZATION CODE
7. AUTHOR(S)
 Michael E.  Eeard  and John H.  Margeson
                                                       8. PERFORMING ORGANIZATION REPORT NO.
9. PERFORMING ORGANIZATION NAME AND ADDRESS
 Quality Assurance  and Environmental Monitoring
  Laboratory
 Methods  Standardization  Branch
 Research Triangle Park.  N.C.  27711	
            10. PROGRAM ELEMENT NO.
                   1HA327
            11. CONTRACT/GRANT NO.
12. SPONSORING AGENCY NAME AND ADDRESS
  Environmental  Protection Agency
  National Environmental  Research Center
  Research  Triangle  Park, N.C. 27711
                                                       13. fXPE Of REPORT AND PERIOD COVERED
                                                         Final
            14. SPONSORING AGENCY CODE
15. SUPPLEMENTARY NOTES
16. ABSTRACT
   Report describes and  evaluates the sodium  arsenite  manual procedure  for
 measurement of NC>2  in  ambient  air.  The evaluation included  ruggedness
 testing, as  described  by Youden.   The  results  showed  a constant-high
 collection efficiency  of  82 ±3.7% over the entire range.  The method involves
 sampling for  24 hours with a  restricted-orifice bubbler immersed in  a
 NaAsO2~NaOH collecting  solution.   The range  of the  method is  approx-
 imately 20 to 750  ug/m  .  The method  was insensitive  to normal  variations in
 orifice bubbler  diameter,  temperature of the absorbing solution during  sampling,
 and concentration  of arsenite.   However,  the  ruggedness test  identified NO
 and CC>2 as  positive and negative interferents, respectively;  sample  flow
 rate  may also  be  a variable affecting the method  response.
   An  assessment  of the  usefulness  of the  method  was  deferred  until  the
 effects of the above interferents  and  of the flow  rate have been  quantitated.
17.
                              KEY WORDS AND DOCUMENT ANALYSIS
                 DESCRIPTORS
b.IDENTIFIERS/OPEN ENDED TERMS  C. COSATI Field/Group
13. DISTRIBUTION STATEMENT

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