EPA-600/1-78-019
March 1978
Environmental Health Effects Research Series
   CONTAMINANTS ASSOCIATED WITH  DIRECT AND
    INDIRECT REUSE  OF MUNICIPAL WASTEWATER
                                   Health Effects Research Laboratory
                                   Office of Research and Development

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                RESEARCH REPORTING SERIES

Research reports of the Office of Research and Development, U.S. Environmental
Protection Agency, have been grouped into nine series. These nine broad cate-
gories were established to facilitate further development and application of en-
vironmental technology.  Elimination of traditional grouping  was consciously
planned to foster technology transfer and a maximum interface in related fields.
The nine series are:

      1.  Environmental  Health Effects Research
     2.  Environmental  Protection Technology
     3.  Ecological Research
     4.  Environmental  Monitoring
     5.  Socioeconomic Environmental Studies
     6.  Scientific and Technical Assessment Reports (STAR)
     7.  Interagency Energy-Environment Research and Development
     8.  "Special" Reports
     9.  Miscellaneous Reports
This report has been assigned to the ENVIRONMENTAL HEALTH EFFECTS RE-
SEARCH series. This series describes projects and studies relating to the toler-
ances of man for unhealthful substances or conditions. This work is generally
assessed from a medical viewpoint, including physiological or psychological
studies. In addition to toxicology and other medical specialities, study areas in-
clude biomedical instrumentation and health research techniques utilizing ani-
mals — but always with intended application to human health measures.
This document is available to the public through the National Technical Informa-
tion Service, Springfield, Virginia  22161.

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                                          EPA-600/1-78-019
                                          March 1978
          CONTAMINANTS ASSOCIATED WITH
DIRECT AND INDIRECT REUSE OF MUNICIPAL WASTEWATER
                       by

                  SCS Engineers
          Long Beach, California  90807
             Contract No. 68-02-2257
                 Project Officer

                Herbert R. Pahren
             Field Studies Division
       Health Effects Research Laboratory
             Cincinnati , Ohio  45268
       HEALTH EFFECTS RESEARCH LABORATORY
       OFFICE OF RESEARCH AND DEVELOPMENT
      U. S. ENVIRONMENTAL PROTECTION  AGENCY
             CINCINNATI, OHIO  45268

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                           DISCLAIMER
     This report has been reviewed by the Health Effects
Research Laboratory, U.S. Environmental Protection Agency, and
approved for publication.  Approval does not signify that the
contents necessarily reflect the views and policies of the U.S.
Environmental Protection Agency, nor does mention of trade names
or commercial products constitute endorsement or recommendation
for use.

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                                                                       V
                            FOREWORD
     The U.S. Environmental Protection Agency was created because
of increasing public and government concern about the dangers of
pollution to the health and welfare of the American people.
Noxious air, foul water, and spoiled land are tragic testimony
to the deterioration of our natural environment.  The complexity
of that environment and the interplay between its components
require a concentrated and integrated attack on the problem.

     Research and development is that necessary first step in
problem solution and it involves defining the problem, measuring
its impact, and searching for solutions.   The primary mission of
the Health Effects Research Laboratory in Cincinnati (HERL)  is
to provide a sound health effects data base in support of the
regulatory activities of the EPA.  To this end, HERL conducts
a research program to identify, characterize, and quantitate
harmful effects of pollutants that may result from exposure  to
chemical, physical or biological agents found in the environment.
In addition to valuable health information generated by these
activities, new research techniques and methods are being devel-
oped that contribute to a better understanding of human biochemi-
cal and physiological functions, and how these functions are
altered by low-level insults.

     This report presents the state of knowledge concerning
levels, removals, and health effects of contaminants associated
with direct and indirect reuse of municipal wastewater for pot-
able purposes.  With a better understanding of the degree of
insult in our drinking water,  measures may be developed to over-
come some of these potentially harmful materials.
                                R.  J. Garner
                                Director
                                Health Effects Research Laboratory
                               iii

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                             PREFACE
                         eyohen           S ""S'iv
natural processes.  In modern times" it ha^becJme  nc?2as?nqly
necessary to reuse water as populations and product vlty haSe
multiplied and limited water supplies have been used UD   How-
ever, this reuse has usually been done on an ^planned basis
It has.been conservatively estimated that, at the Srlsent time
approximately one-third of the population in the uSued Statel'
derives water from sources which are degraded to some extent
by wastewater discharges   Excepting the transmission of
infectious diseases, little concern - until very recent!*   b**
been given to the disease-producing potential^ s5ch cog-
nation.  It is now necessary to review the health effects of
this situation in a more comprehensive fashion.

     Since the public health disaster of Minimata, Jaoan  in
the late 1950's and early 1960's (caused by ingestion o?'shell-
fish contaminated with methyl mercury) there has been a areat
surge in research concerning environmentally induced health
effects on man.  It is now generally accepted that the mvriad
of contaminants which are continuously discharged to the
environment may produce both acute and chronic repercussions
or public health through daily ingestion of air, water  and
food.  Recently, some forms of cancer, once thought to'be of
genetic etiology, have been projected to be caused or stimu-
lated by environmental contaminants.

     One area of critical consideration to public health is
the direct or indirect reuse of municipal wastewater for potable
purposes.  Municipal wastewater systems have been the reposi-
tories of virtually every chemical contaminant known to be
produced by man.  The very nature of municipal wastewater
streams makes them of critical importance when considering the
environmentally induced health effects on man.  Many questions
must be clearly answered before a complete understanding of the
situation will occur:  What are the harmful constituents of
municipal wastewater?  How well does our present wastewater
treatment technology remove these constituents?  What eventu-
ally happens to them in the environment?  How well do our
water treatment plants perform in providing Contaminant
removals and a last line of protection?  What are the effects
                               IV

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of the contaminants on the health and well-being of man?  This
report is an attempt to assemble and evaluate the existing
literature pertinent to these questions.  It is not an in-depth
study.  Rather, it is intended to serve as a basis for deter-
mining the health risks involved and the future research require-
ments for direct and indirect potable water reuse.

     For purposes of this report, direct reuse is defined as the
discharge of the treated municipal wastewater directly into a
raw water supply without intervening travel, and dilution in
natural surface or groundwater.  No such direct reuse currently
exists in the United States; however, direct reuse has been
practiced in South Africa for about ten years, and long-range
plans for direct reuse are being considered in some United
States municipalities (e.g., Denver).

     Indirect reuse is defined as the reuse of treated muni-
cipal wastewater as a raw water supply after the wastewater
has entered, comingled, and essentially become a part of a
natural surface or groundwater resource.  A significant per-
centage of the nation's raw water supply is derived from surface
waters such as major lakes and rivers, and consists in part of
treated wastewater from other municipalities.  This indirect
reuse has long been accepted by the public and the waterworks
industry as normal and inevitable.  Indirect reuse also in-
cludes introduction of treated wastewater into groundwater
aquifers through percolation or well injection.  This practice
is often labeled groundwater recharge and may be a formal,
intentional program, or simply a result of land disposal of
wastewater.

     Obviously, in some cases there is only a fine line
separating direct reuse from indirect reuse.  For example, if
a municipal water department owns and operates a large raw
water storage reservoir and treated wastewater is introduced
into that reservoir, even as a relatively small percentage
of the "fresh" water volume, that is considered direct reuse.
Conversely, a large volume of the wastewater in a river in the
Midwest may come from wastewater from upstream municipalities,
and yet a water supply taken from that river would be considered
indirect reuse.  Advocates of direct reuse point to comparisons
of this type to show that the stigma attached to well-designed
direct reuse is irrational.  Opponents of direct reuse answer
that "two wrongs don't make a right," and that insufficient
knowledge exists about both direct and indirect reuse to ensure
a "safe" water supply for the public.

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                            ABSTRACT
     This report is an attempt to compile the published quanti-
tative data available concerning the health effects associated
with direct and indirect reuse of treated municipal wastewater
for potable purposes.  The assembled information includes data
on the effectiveness of conventional water and wastewater treat-
ment and disposal  operations in reducing public health contami-
nant concentrations, as well as data on the transport of these
contaminants through the environment back to man.   The data have
been organized in  such a manner that the various pathways of
pollutants to man  can be evaluated for relative public health
significance in order to establish necessary research priorities.

     Wastewater treatment processes evaluated include conven-
tional secondary treatment and tertiary processes.   Wastewater
disposal techniques evaluated include direct discharge to fresh
surface waters and land application.  Water treatment processes
evaluated include  conventional treatment (chemical  coagulation,
with or without filtration, and disinfection) and advanced water
treatment (carbon  adsorption, ion exchange, and reverse osmosis),
A discussion of p.ublic health considerations is also included.
                               VI

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                            CONTENTS
Foreword	    iii
Preface	     iv
Abstract	     y1
Figures	     1X
Tables   	      x
Section

   1     Introduction
6
           Objectives
           Scope
           Approach

   2    Wastewater Inputs

   3    Primary Treatment

   4    Secondary Treatment

           Activated sludge
           Trickling filter
           Aerated lagoons
           Ponding
   5    Tertiary Treatment
           Filtration
           Adsorption
           Chemical treatment
           Ion exchange
           Nitrogen removal  processes
        Disinfection  ...................    83
            Chlorination
            Ozonation
    7     Land/Groundwater

    8     Fresh  Surface  Water
                                vii

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 9    Conventional Water Treatment 	    158

         Chemical  coagulation and flocculation followed
           by solids separation   	    158
         Disinfection  	    180

10    Advanced Water Treatment 	    191

         Adsorption onto activated carbon
           and other materials	    191
         Ion exchange	    209
         Reverse osmosis 	    220

11     Epidemic!ogical and Pathological  Evaluation
      of Wastewater Contaminants 	    230

         Introduction  	    230
         Water quality parameters  	    231
         Elemental contaminants  	    234
         Biocidal  contaminants 	    243
         Synthetic/organic contaminants  	    252
         Biological contaminants 	    257

REFERENCES	    287
                           vlii

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                             FIGURES
Number                                                     Page

   1     Environmental  pathways for direct and
          indirect potable reuse 	    4
   2    Unplanned wastewater reuse exists for
          many groundwater supplies  	   97

   3    Methods of planned recharge  	   99

   4    The effectiveness of a small  amount of
          N-607 polymer relative to alum for raw
          water with a turbidity of 1-250 Jtu	165
                               ix

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                             TABLES

Number                                                     page
   1     Water Quality Parameters 	      5
   2     Elemental  Contaminants 	      6
   3     Biocidal  Contaminants  	      6
   4     Organic Compound Identification New
          Orleans  Water Study  	      7
   5     Biological  Contaminants  	      9
   6     Literature  Review Pertaining To The Composition
          of Wastewater Inputs To Municipal Treatment
          Systems	     11
   7     Summary of  Water Quality Parameters
          Characterizing Wastewater Input to Municipal
          Treatment Facilities 	     15
   8     Summary of  the Concentration Ranges of
          Elemental Contaminants Found in Wastewater
          Inputs to Municipal Treatment Systems  	     17
   9     Average Heavy Metal Loadings and Probable
          Sources  for Twelve New York City Municipal
          Treatment Plants 	     18
  10     Summary of the Concentration Ranges of
          Biological  Contaminants Found in Wastewater
          Inputs to Municipal Treatment Systems  	     19
  11     Distribution of Fecal Streptococci in
          Domestic Wastewater and Stormwater Runoffs  ...     20
  12     Literature Reviewed Pertaining to  Primary
          Wastewater Treatment  	     22
  13     Primary Settling Tank Performance  	     24
  14    Primary Treatment  Removal of Metal Elements   ...     24

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Number                                                      Page
  15    Survival  of Pathogens During Primary
          Treatment	    26
  16    Literature Reviewed Pertaining to
          Activated Sludge 	    29
  17    Activated Sludge Treatment Pollutant
          Removals, Los Angeles, CA	    32
  18    Removals  of Trace Metals by Activated
          Sludge  Processes, Los Angeles, CA  	    33
  19    Percent Removals of Trace Metals by the
          Activated Sludge Process 	    34
  20    Possible  Carcinogens Included in the Analysis  .  .    35
  21    Removal of Pathogens by the Activated
          Sludge  Process 	    36
  22    Percent Removals of Biological Pathogens
          by the  Activated Sludge Process  	    36
  23    Viral  Removal  by Activated Sludge Treatment  ...    37
  24    Literature Reviewed Pertaining to
          Trickling Filters  	    40
  25    Trickling Filter Process Removal of Trace
          Metal Contaminants	    42
  26    Removal of Pathogens by Trickling Filters  ....    43
  27    Literature Reviewed Pertaining to
          Aerated Lagoons  	    45
  28    Literature Reviewed Pertaining to Ponding  ....    47
  29    Literature Reviewed Pertaining to Filtration ...    50
  30    Results of Ontario, Canada Pilot Plant Study
          Involving Filtration Preceded by Chemical
          Treatment of Secondary Effluent  	    52
  31    Heavy  Metal Removal by Sand Filtration
          Following Lime Coagulation 	    53
  32    Removal of Poliovirus I from Ca(OH)2 Flocculated
          Effluent by  Rapid Sand Filtration as Measured
          by Membrane  Filter Recovery of Virus 	    55
                              xi

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33
34

35

36
37

38

39

40
41
42

43

44

45
46
47
48
49

50

51


Literature Reviewed Pertaining to Adsorption . . .
Removal of Specific Toxic Materials by
Carbon Adsorption . . .
Literature Reviewed Pertaining to
Chemical Treatment 	 ....
Removals Achieved by Chemical Clarification . . .
Removal of Elemental Contaminants by
Lime Coagulation 	
Comparison of the Effectiveness of the
Coagulants Tested 	
Removal of Polio Virus 1 from Secondary
Effluent by Flocculation with Ca(QH)z 	
Literature Reviewed Pertaining to Ion Exchange . .
Trace Metal Removals by Ion Exchange 	
Literature Reviewed Pertaining to
Nitrogen Removal 	
Effluent Nitrogen Concentrations in
Treatment Systems Incorporating
Nitrification-Dentifrication 	
Literature Reviewed Pertaining to
Chlorination 	
Identification of Chlorine Containing
Constituents in Chlorinated Effluents 	
Chlorinated Organics in Wastewater Effluent . . .
Effect of Chlorination on Various Organisms . . .
Literature Reviewed Pertaining to Ozonation . . .
Survival of Polio Virus in Ozonation
Continuous Flow Studies 	
Nitrogen Transformation in Recharge
Aquifer, MG/1 	
Nitrogen Transformations Resulting from
Different Spreading Techniques 	
:,. " a .
57

61

65
68

69

72
"7 O
73
75
77
O 1
81

82

84
86
87
88
92

95

103

104
xii

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Number                                                     Page
  52    Survival  of Pathogens in Soils	   113
  53    Percentages of the Total Amounts of Iron,
          Nickel,  Cobalt,  Chromium,  Copper, and
          Manganese Transported by Five Mechanisms
          in the  Yukon and Amazon Rivers	   122
  54    Heavy Metal Distribution in  Streams  	   123
  55    Metals Coordinated by Ligands Normally
          Found in Natural Waters	   125
  56    Selected  Concentrations of Mercury in
          Natural  Waters 	   130
  57    Mercury Content of Sediments and Plankton/Algae
          Samples  Collected From Lake Erie	   131
  58    Biocide Types  and  Examples 	   135
  59    Persistence of Compounds in  River Water  	   137
  60    Estimated  Pesticide Half-Lives 	   136
  61    Chlorinated Hydrocarbon Insecticides  in
          Southern Lake Michigan Sediments 	   139
  62    DDT Concentrations in Stream Sediments 	   140
  63    Dieldrin  in River  Bottom Silts 	   138
  64    Organic Compounds  identified to Date
          From Lower Tennessee	   143
  65    Organic Compound Identifications
          New Orleans  Area Water Supply Study  	   144
  66    Molecular  Constituents Identified in
          Natural  Water Samples  	   152
  67    PCB Concentrations in Selected Water  Courses  .  .  .   153
  68    Average Time in Days  for 99.9% Reduction  of
          Original  Titer of Indicated Microorganisms
          in Waters	   155
  69    Survival  of Enteric Viruses  in Water  	   157
  70    Literature Pertaining to Chemical
          Coagulation  and  Clarification  	   160
                             xiH

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Number                                                     Page

  71     A Comparison of the Effectiveness  of the
          Coagulants Tested on the Raw Surface  Water  .  .  .   163

  72     Typical  Three-Media High-Rate Filtration
          Plant  Performance	   167

  73     Percentage of Pesticide Removed by
          Conventional  Treatment 	   172

  74     Reduction  of Human  Enteric Viruses in
          Water  by Chemical  Flocculation	   178

  75     Literature Reviewed Pertaining to
          Water  Disinfection	   181

  76     Effect of  Ozonation on Chlorinated
          Hydrocarbon Insecticides 	

  77     Probable Reaction  Products, of Chlorine  and
          Some Typical  Organic Compounds Found  in
          Polluted Water Supplies  	

  78     Viricidal  Efficiency of Free Chlorine in  Water .  .   187

  79     Literature Reviewed Pertaining to  Adsorption  ...   192

  80     Summary  of Water Quality Analysis  Data  From         .
          Activated Granular Carbon  	   I9o

  81     Activated  Carbon Filtration at Colorado
          Springs  Pilot Plant  	   '94

  82     Odor Imparted to Odor-Free Water by Pesticides
          and Herbicides	   197

  83     Activated  Carbon Required to Reduce Odors
          Caused by Pesticides and Herbicides to
          Palatable Levels 	   198

  84     Removal  of Heavy Metals by Percolation  with
          Granular Low Volatile Matter Attapulgite Clay.  .   199

  85     Activated  Carbon Removals of Chlorinated
          Hydrocarbons Achieved in Laboratory
          Experiments	   202

  86     Removal  of Specific Toxic Materials by
          Carbon Adsorption  	                    202
                              xiv

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Number                                                      Page
  87    Summary of Cumulative Pesticide Removal
          at 10-ppb Load	   203
  88    Removal of Organics by Percolation With
          Granular LVM Attapulgite 	   206
  89    Adsorption of Organic Compounds onto
          Amberlite XAD-2 Polymeric Adsorbent  	   207
  90    Ion Exchange Resins Selectivity  	   209
  91    Literature Reviewed Pertaining to Ion Exchange .  .   211
  92    Average Water Quality Characteristics of the
          Ion Exchange Pilot Plant Under Typical Operation
          Conditions	   213
  93    Removal of Trace Elemental Contaminants
          From Water by Ion Exchange	   216
  94    Ion Exchange Treatment for Inorganic Mercury . .  .   218
  95    Literature Reviewed Pertaining to Reverse
          Osmosis	   222
  96    Reverse Osmosis Removal of Elemental
          Contaminants 	   226
  97    Metals in the Environment and Their Toxicity . .  .   235
  98    Biocides in the Environment and Their Toxicity .  .   244
  99    Summary of Results of Introducing CCE and CAE
          from Raw and Finished Water into Mice	   254
 100    The Minimal Carcinogenic Dose for Three  of
          the Most Potent Carcinogenic Hydrocarbons
          in Susceptible Experimental Animals  	   255
 101    Waterborne Disease Outbreaks 	   257
 102    Waterborne Disease Outbreaks, by Etiology
          and Type of Water System, 1975	   258
 103    Clinical Response of Adult Humans to Varying
          Challenge Doses of Enteric Pathogens 	   261
                              xv

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Number

 104    Average Values for C.  Albicans, Coliform
          and Fecal  Coliform Counts and TOC (Total
          Organic Carbon)  Determinations in the
          Estuarine  Water  Samples,  Long Island,
          New York	   266

 105    U.S.  Mortality from Selected Causes Related
          to  Water Pollution	   267

 106    Relation of  Dosage of  S_._ Typhosa to Disease  .  .  .   268

 107    Dose  of Various Species and Strains of
          Salmonella that  Caused Disease in
          Human Volunteers	   269

 108    Mean  Indicator Densities at the Coney Island
          and Rockaways Beaches, New York,  During 1973
          and 1974 Trials	   272

 109    Symptom Rates  in Percent at Coney Island
          and Rockaways Beaches, New York,  During
          1973 and 1974 Trials	   273

 110    The Human Enteric  Viruses and the Diseases
          Associated With  Them	   276

 111     The Human Enteric  Viruses that Can  be
          Waterborne and Known  Diseases Associated
          with These Viruses	   277

 112    Published Reports  of Poliomyelitis  Attributed
          to  Contaminated  Drinking  Water 	   283

 113    Minimal  Infective  Doses of  Attenuated Polio
          Viruses for  Human Hosts by Oral  Routes	   285
                              xvi

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                            SECTION 1

                          INTRODUCTION
OBJECTIVES
     The purpose of this report is to clearly describe the state-
of-the-art knowledge pertinent to potential  health effects from
direct and indirect reuse of treated municipal  wastewater for
potable purposes.   No new basic research is  intended.   Rather,
the report ties together the results of past and ongoing research:

     t  The ranges of concentrations of contaminants contained
        in the influent to municipal wastewater treatment plants;

     0  The effectiveness of conventional  wastewater treatment
        processes  in the removal, modification, or inactivation
        of these contaminants;

     •  The potential hazards associated with effluent disposal
        practices  in regard to the introduction of contaminants
        to the ecosystem;

     •  Pathways by which contaminants associated with wastewater
        treatment/disposal operations can intersect with man;

     •  The effectiveness of conventional  water treatment
        processes  in the removal, modification, or inactivation
        of these contaminants;

     •  The chronic and acute effects of the contaminants within
        the human  body.

SCOPE

     This report compiles the published quantitative data
available concerning the potential health effects associated
with direct and indirect reuse of treated municipal wastewater
for potable purposes.  The assembled information includes data
on the effectiveness of conventional water and wastewater treat-
ment and disposal  operations in reducing public health contami-
nant concentrations, as well as data on the transport of these
contaminants through the environment back to man.  The data
have been organized in such a manner that the various pathways
of pollutants to man can be evaluated for relative public

                                 1

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health significance in order to establish necessary research
priorities.

     Wastewater treatment processes evaluated include conven-
tional secondary treatment and tertiary processes.   Wastewater
disposal  techniques evaluated include direct discharge to fresh
surface waters and land application.  Water treatment processes
evaluated include conventional treatment (chemical  coagulation,
with or without filtration, and disinfection) and advanced
water treatment (carbon adsorption, ion exchange, and reverse
osmosis).

APPROACH

     This project was accomplished in three distinct phases
or tasks:

Task I -  Literature Review

     The  first task reviewed the present literature, providing
information and data relevant to the health effects associated
with the  direct and indirect reuse of municipal  wastewater for
potable purposes.   The relevant literature included the
transport and losses of the various contaminants through the
various pathways and unit operations between the raw waste and
usable drinking water.

Library Research--

     Research assistants obtained copies of Pe^1nfn* !l*erj~
ture from several  major university libraries, the Library of
Congress, information retrieval  systems (e.g., NJJJ), and the
SCS Engineers in-house library.   Due to the breadth of the
topic, several  constraints were placed upon the  literature
search in order to assure a workable, yet comprehensive, volume
of information.  Major constraints follow:

     •  Only literature published within the last ten years
       was  reviewed, except in unusual circumstances.

     •  Except in  unusual circumstances, only literature
       directly addressing wastewater and water treatment
       and  disposal, and health effects was reviewed.
       There is,  of course, a large volume of related
        literature (e.g., biological, medical, meteoro-
        logical) that could provide additional insights;
        however, this peripheral literature was  excluded
        from the investigation.

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Correspondence--

     To obtain the very latest scientific information available,
as well as to find areas in which research is presently being
conducted, letters were sent soliciting literature and data
from thefollowing information sources:

     •  State regulatory and public health agencies;


     •  Major sanitary districts known to be conducting
        research; and

     •  Universities conducting related research.

The responses from these sources have  been incorporated into
the project.

Task II - Data Analysis

     The data and information obtained in Task I were organized
and analyzed to trace the movements and losses of the various
contaminants through the pathways associated with direct and
indirect reuse of municipal wastewater.  These pathways included
the waste treatment system, any applicable environmental path-
ways such as river transport or groundwater, and the potable
water treatment plant.  The potential  health significance of
this transport of the contaminants was delineated where infor-
mation was available.

Task III - Report Preparation

     This report is organized by pathway, rather than by
contaminant, so that various public health impairing contami-
nants can be traced through wastewater treatment plants,
through the biosphere, and finally back to man.  Figure 1
illustrates the alternate pathways that various contaminants
may follow to reach man after leaving the wastewater treatment
plant.  In dark relief are those pathways associated with direct
and indirect reuse for potable purposes.

     Each major wastewater and water treatment step and disposal
method is treated in a separate subsection of the report.  The
report does not, however, contain a separate section for each
contaminant.  If the reader is interested in mercury, for
example, he must skip through the report and read about the
fate of mercury during individual treatment  processes, when
released to the biosphere, and the consequent health effects on
man.  To facilitate the task of tracing a single contaminant
through the report, each section is divided  into subsections
by contaminant type.

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                               FIGURE I. ENVIRONMENTAL PATHWAYS  FOR DIRECT

                                       AND INDIRECT  POTABLE  REUSE.

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     The selection of wastewater contaminants for consideration
in this study was difficult, because of the many public  health
impairing constituents found in wastewater.  Several  of  the
traditional wastewater parameters (BOD, suspended solids, etc.)
pose no direct threat to public health, although some of the
direct health-impairing contaminants may be associated with
these traditional wastewater parameters.  Therefore,  some of
the traditional  parameters are included.

     Within each section of this report (which traces waste-
water contaminants through municipal wastewater treatments,
through the environment, and through water treatment plants,
and which details the  epidemiological and  pathological effects
on man) information  is organized and presented in the following
contaminant groups:

     1.  Water Quality Parameters
     2.  Elemental Contaminants
     3.  Biocidal Contaminants
     4.  Synthetic/Organic Contaminants
     5.  Biological  Contaminants

     The water quality parameters group contains those water
measurements  that are  traditionally  associated with  wastewater
treatment  systems, as  well as  those  contaminants that do  not
readily fit  in any other category.   Table  1   lists  these  water
quality parameters.   Most of the parameters  listed in this
table do not  pose a  direct threat to public  health,  but  may be
related to public health  impairing  contaminants.  For example,
heavy metals  or  viruses may be  adsorbed to the  surface  of
suspended  solids and  may  be transported through  the  wastewater
treatment  plant  and  biosphere  in this  manner.   However,  the
nitrogenous  compounds  (ammonia,  nitrates,  and nitrites)  may
directly threaten public  health.


              TABLE  1  .   WATER QUALITY  PARAMETERS


       1.   Ammonia
       2.   Biochemical  Oxygen  Demand  (BOD)
       3.   Chemical Oxygen Demand (COD)
       4.   Nitrates
       5.   Nitrites
       6.   Phosphates
       7.   Suspended  Solids
       8.   Total  Dissolved Solids (TDS)
       9.   Total  Organic  Carbon (TOC)

-------
      The  elemental  contaminants  group,  consists of the  ions,
compounds, and complexes of the metals  and metalloids  listed  in
Table 2.  Many of these contaminants are required  in  trace quan-
tities for normal human metabolic functions,  yet higher levels  of
these trace elements may cause significant health  problems.

                TABLE   2 .   ELEMENTAL CONTAMINANTS
1 . Aluminum
2. Antimony
3. Arsenic
4. Barium
5. Beryl 1 ium
6. Boron
7. Cadmium
8. Chromium
9.
10.
11 .
12.
13.
14.
15.
16.
Cobalt
Copper
Germanium
Iron
Lead
Manganese
Mercury
Molybdenum
17.
18.
19.
20.
21.
22.


Nickel
Sel enium
Thorium
Tin
Uranium
Zinc


      Biocidal contaminants are those contaminants normally
used  to control insect or disease vectors.  Table 3  lists tnese
biocidal contaminants.  DDT, ODD, DDE, aldrin, dieldrin, and
endrin are all chlorinated hydrocarbons; they were considered
separate from the chlorinated hydrocarbon classlfication
because the literature often dealt with these specific  pesti-
cides as individual entities.
     1.
     2.
     3.
     4.
     5.
     6.
DDT
DDD
DDE
Aldrin
Dieldrin
Endrin
BIOCIDAL CONTAMINANTS

      7.  Chlorinated hydrocarbons
      8.  Arsenated hydrocarbons
      9.  Organonitrogen pesticides
     10.  Organophosphorus pesticides
     11.  Herbicides
     12.  Soil sterilants
     The synthetic/organic contaminants group  includes many
synthetically produced organic chemicals that  have found their
way into water systems.   For  the purposes of this report,
information was gathered  on any synthetic/organic chemicals in
wastewater treatment  processes or the biosphere.  A selection
of such contaminants, recently identified by the Environmental
Protection Agency  in  an evaluation of organic  comoounds in the
New Orleans area water supply are listed in Table 4,

     Traditionally, biological contaminants have received the
most attention in  wastewater  treatment, since  these contami-
nants may directly cause  infection in the consumer.  Biological
contaminants considered in this study are listed in Table 5.

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         Table  4.  ORGANIC COMPOUND IDENTIFICATION
             NEW ORLEANS AREA WATER SUPPLY STUDY  ( 61 5 )
 1 .   Acetaldehyde
 2.   Acetone
 3.   Alkylbenzene-C2 isomer
 4.   Alkylbenzene-C2 isomer
 5.   Alky1benzene-C2 isomer
 6.   Alkylbenzene-Cg isomer
 7.   Alkylbenzene-Cj isomer
 8.   Alkylbenzene-Cj isomer
 9.   Atrazine
     (2-chloro-4-ethylamino-
     6-isopropylamino-s^-
     triazine)
10.   Deethylatrazine
     (2-chloro-4-amino-
     6-i sop ropy 1 ami no- s_-
     triazine)
11.   Benzyl butyl phthalate
12.   Bromodichloroethane
13.   Bromoform
14.   Butanone
15.   Carbon disulfide
16.   Carbon tetrachloride
17.   bis-2-Chloroethyl  ether
18.   Chloroform
19.   bis-2-Chloroisopropyl
     ether
20.   n-Decane
21.   Decane-branched isomer
22.   Dibromodichloroethane
     i somer
23.   Dibromochloromethane
24.   Dibutyl phthalate
25.   2,6-Di-t-butyl-p_-
     benzoquinone
26.   Dichlorobenzene isomer
27.   1 ,2-Dichloroethane
28.   Dichloromethane
29.   Dieldrin
30.   Diethyl phthalate
31.   Di(2-ethylhexyl)
     phthalate
32.   Dihexyl phthalate
33.   Dihydrocarvone
34.   Diisobutyl phthalate
35.   Dimethyl phthalate
36.   Dioctyl adipate
37.   Dipropyl phthalate
38.   n-Dodecane
39.   Endrin
40.   Ethanol
41.   p_-Ethyl toluene
42.   p_-Ethyl toluene

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 TABLE 4  (continued)
43.  1,2,3, 4, 5, 7, 7-
     Heptachloronorbornene
44.  Heptachloronorbornene
     isomer
45.  Hexachloro-1,3-butadiene
46.  Hexachloroethane
47.  Isophorone
48.  Limonene
49.  Methanol
50.  Methylbenzoate
51.  3-Methylbutanal
52.  2-Methylpropanal
53.  n-Nonane
54.  n-Pentadecane
55.  Tetrachloroethane isomer
56.  Tetrachloroethylene
57.  n-Tetradecane
58.  Toluene
     1 ,1,2-Trichloroethane
     1,1,2-Trichloroethylene
     n-Tri decane
59
60
61
62
63
64
Trimethyl-trioxp-
hexahydrotrlazine Isomer
Triphenyl phosphate
n-Undecane
65.  Undecane-branched isomer

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    TABLE  5.   BIOLOGICAL CONTAMINANTS
 1.   Adenovirus
 2 .   C1 ostrich'urn botulinum
 3.   C1ostridium perfringens
 4.   Coliforms
 5.   Coxsackie  virus (A&B)
 6.   ECHO virus
 7 .   Erysipelothi ix rhusiopathie
 8.   Escherichia coli
 9.   Fecal streptococci
1 0.   Franci sel1 a tularensis
11.   Hepatitis  virus
12.   Leptospira
13.   Listeria monocytogenes
14.   Mycobacterium
15.   Parasitic  worms
16.   Polio virus
17.   Protozoa
18.   Salmonella
19.   Shigella
20.   Staphylococcus aureus
21.   Vibrio cholerae
22.   Yeasts

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                            SECTION 2

                        WASTEWATER  INPUTS
INTRODUCTION
     Untreated  wastewater  input  composition  is  the first point of
interest in  determining  the  pathways  pollutants  may JjJ1^™"
wastewater management systems  back  to  man  in  dl ^V^1^:^
reuse situations.   In addition  to domestic  sewage, Tnput sources
may include  various industrial  wastes,  storm  water, and ground-
water infiltration, in various  combinations.   Moreove  ,        P
proportions  of  an  individual  system change  with t^e   Po
concentrations  and volumes va.x-\j
      Research surveyed regarding input concentrations to munici-
 pal treatment facilities is presented in Table 6 .   Substantial
 literature concerning input compositions is available for water
 quality parameters and elemental and biological contaminants.
 With few exceptions, however, input concentrations  of biocidal
 and synthetic-organic contaminants have not been investigated.
 It was therefore difficult to determine the effect  of subsequent
 treatment processes upon such contaminants.  Regulations for
 industrial  discharges of complex mixtures of organic compounds
 generally only require reporting of the BOD or COD, suspended
 solids, and similar water quality parameters.  In many instances,
 industrial  concerns themselves may not know the detailed compo-
 sition of their waste streams.

      Since 1972, the development of the National Pollution
 Discharge Elimination System  (NPDES) permit programming has
 changed the typical input composition to municipal  sanitary
 systems through increased restrictions on inputs from industrial
 waste.  In particular, these  restrictions have reduced the
 amount of heavy metal contaminants entering municipal treatment
 systems .

      Municipal treatment systems that process  only domestic
 wastes and that have no excessive infiltration show  predictable
 diurnal and seasonal patterns.  However, most  urban  sanitary
 systems and many rural systems  also contain  industrial wastes.
 Composition and flow volumes  may vary significantly  as a func-
 tion of these industrial inputs.  Food  processing  plants can


                                10

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  TABLE 6.  LITERATURE REVIEWED PERTAINING TO THE COMPOSITION
       OF WASTEWATER INPUTS TO MUNICIPAL TREATMENT SYSTEMS
Contaminant
          Reference Number
Water Quality Parameters

  Ammon ia


  BOD



  COD


  Chlorides

  Cyanides

  Fluorides

  Nitrates


  Nitrites


  Oil & grease

  Phosphates



  Suspended solids


  Total dissolved
  sol ids

  Total organic
  carbon

  Other (general)

 Elemental Contaminants

  Aluminum

  Arsenic
22, 90, 273, 368, 390, 406, 450, 503,
516, 582, 647,  651, 700

19, 69, 171, 251, 273, 302, 345, 368,
390, 450, 503,  526, 569, 647, 651, 653,
700

19, 69, 134, 171, 251, 312, 390, 391,
450, 516, 526,  582, 647, 651, 700

19, 22, 161, 450, 516

390

390

22, 90, 273, 368, 406, 450, 503, 510,
516, 582, 647,  651

90, 273, 368, 390, 406, 450, 503, 516,
582, 647, 651,  700
541
19, 22, 69, 132, 134, 161, 273, 304,
368, 390, 406, 450, 516, 582, 647, 651,
700

22, 134, 171, 312, 368, 516, 526, 582,
647, 651, 653, 700

1, 390, 647
69, 134, 312, 516, 647


7, 312



26, 134, 390, 538

19, 390
                               11

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TABLE 6 (continued)
Contaminant	Reference Number	
  Barium               19, 390
  Cadmium              19, 37, 159, 390,  391, 471, 702
  Chromium             19, 134, 159, 390, 391, 462, 471, 473,
                       702
  Cobalt               134,  273,  390, 471, 702
  Copper               19, 107, 134, 159, 273, 390, 471, 702
  Iron                 26, 134, 273, 450, 471, 538, 702
  Lead                 19, 107, 134, 390, 471, 493
  Manganese            134,  273,  390, 450, 471, 702
  Mercury              19, 392, 471
  Molybdenum           390,  702
  Nickel                107,  159,  273, 390, 471, 702
  Selenium             19, 390, 391
  Tin                  390
  Zinc                 19, 26, 107, 134,  159, 390, 702
Synthetic/Organic         317  434^  702
 Contaminants
Biological  Contaminants
  Coliforms            134>  163>  251» 368» 390« 526>
  ECHO virus           56°
  Fecal  streptococci    163,  236,  390, 560
  Mycobacterium        223
  Parasitic worms      223
  Polio  virus          560
  Protozoa             223
                               12

-------
TABLE 6 (continued)
Contaminant                      Reference  Number
  Salmonella            223,  339



  Shigella              223



  Virus                198,  221

-------
contribute seasonally high BOD discharges;  large metal  platers
and metal finishers may periodically contribute high metal
waste concentrations.  Certain situations require particular
attention when evaluating potential  adverse effects on  human
health, including:

     t  Large hospital complexes connected to small sanitary
        systems;

     •  Situations in which large amounts of waste from metal
        platers and metal finishers discharge to the system;

     t  Tanneries .discharging to the system;

     •  Petrochemical and related complexes;

     •  Biocide manufacturing facilities;

     •  Specialty  chemical manufacturing or formulating facil-
        ities; and

     0  Combined or heavily infiltrated systems that bypass
        excess flow without adequate treatment.

WATER QUALITY PARAMETERS

     The water quality parameters that characterize wastewater
entering into a sanitary treatment plant have been extensively
studied.  Concentration ranges recorded in the reviewed litera-
ture are presented in Table 7 .   Atypical situations that lie
outside these ranges are known to occur under special conditions.
Such exceptions can usually be attributed to excessive industrial
inputs, excessive infiltration,  or unusual characteristics of
the fresh-water supply to the service area.

     Diurnal flow patterns reported by Nomura and Young ( 486 )
show that suspended solids concentrations in raw sewage are
directly related to sewage flow rates.  The suspended solids
content of the raw sewage studied ranged from 20 mg/l in the
late night flow (attributed to infiltration) up to a high of
350 mg/l during the peak daily sewage flow rate.

     Storm and municipal systems show considerable variation in
flow rate as a function of time; consequently, contaminant con-
centrations vary greatly ( 7,  368,  502 ).  Water quality
parameter variations due to storm system input will be a
function of:

     •  Normal concentrations during dry weather flow
     t  Amount and duration of precipitation
     •  Time since the last rain
     •  Season

                              14

-------
     TABLE   7 .   SUMMARY OF WATER QUALITY PARAMETERS
           CHARACTERIZING WASTEWATER INPUT TO
             MUNICIPAL TREATMENT FACILITIES*
Constituent	Range,  mg/l
Ammonia nitrogen                          8 to 50
Total nitrogen                            20 to 85
Organic-nitrogen                          5 to 32
Nitrate-nitrogen                          0 to 3
Nitrite-nitrogen                          0 to 1
Chloride                                  25 to 203
Oil and grease                            1 to 50
Total phosphorus                          4 to 50
Phosphate as PO,                          5 to 50
Inorganic phosphorus                      8 to 13
Organic phosphorus                        1 to 5
BOD                                       30 to 600
COD                                       100 to  1000
Suspended solids                          30 to 350
Total dissolved solids                    250 to  1400
*As reported in the literature reviewed.
                         15

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ELEMENTAL CONTAMINANTS

     The type and amount of elemental  contaminants  contained  in
any treatment system input will  depend primarily  upon  the  type
and amount of industrial wastes  entering  that  system.   A great
deal of material is available on industrial  discharges  to  muni-
cipal  systems.   A summary range  of elemental  influent  character-
istics as reported in the literature is presented in Table 8.
The Interim Drinking Water Standards have been  included to provide
a standard of comparison.

     The literature  reviewed did  not  provide a comprehensive
survey of the sources of  these metallic  contaminants,  but  the
following factors  appear  to  be  important:

     •   Input water  composition

     •   Input water  scaling  and corrosion potential

     •   Type and age of domestic  water piping systems

     •   Type and amount of industrial  discharges

     •   Type of municipal system  (combined or separate storm
         water).

     The relative  significance of these  factors  will again
depend upon the specific  site.  The results of a study by  Davis
and Jacknow (159)  of the  12  municipal  treatment  plants in  New
York City (presented in Table  9  )  give  some idea of the  ratio
of contributions from various sources  that might be expected in
a large  urban area.  This same study  contains source breakdowns
for individual plants.   Input from  the residential sector  con-
tained concentrations exceeding the Interim Primary Drinking
Water Standards by a factor  of 2.

     A knowledge of  the physical  and  chemical forms of elemental
contaminants is necessary in order  to  adequately evaluate
potential public health effects.  In  particular, it is necessary
to know whether these elements are  present as particulate
materials or soluble species.  Data of this type are apparently
unavailable at this  time.

BIOLOGICAL CONTAMINANTS

     Information available in the  literature  concerning input
concentrations of biological  contaminants generally  addresses
primary indicator organisms rather than specific  pathogens.   A
summary range of biological  contaminants  reported in this
literature is presented  in Table 10.
                               T6

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     TABLE  8 .   SUMMARY OF THE CONCENTRATION RANGES OF
      ELEMENTAL CONTAMINANTS FOUND IN WASTEWATER INPUTS
               TO MUNICIPAL TREATMENT SYSTEMS*
Consti tuent
Range (mg/l)
Interim Drinking
Water Standards
Aluminum
Antimony
Arsenic
Barium
Beryllium
Boron
Cadmium
Chromium
Cobalt
Copper
Germanium
Iron
Lead
Manganese
Mercury
Molybdenum
Nickel
Selenium
Thorium
Tin
Uranium
Zinc
0.3 to 3.0
No data in literature
0 to 0.02
0 to  0.02
No data in literature
0.5 to 3
0.01 to 0.2
0.01 to 0.3
No data in literature
0.01 to 0.5
No data in literature
0.5 to 6.5
0 to 1
0.05 to 0.15
0..0002 to 0.003
No data in literature
0.05 to 0.5
0 to 0.11
No data in literature
No data in literature
No data in literature
0.01 to 2.10
      .05
       1
      .01
      .05
      .05
      .002
      .01
*As reported in  the  literature  reviewed.
                              17

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              TABLE   9 .   AVERAGE HEAVY METAL LOADINGS AND PROBABLE SOURCES FOR
                   TWELVE NEW YORK CITY MUNICIPAL TREATMENT PLANTS (159 )
00


Metals

Copper
Chromi um
Nickel
Zi nc
Cadmi um


Total
Loading
3,820
2,340
1,870
10,440
341


Electroplati ng
and
Photoengravi ng
611
345
1 ,010
830
65


Percent-
age of
total
15
14
53
7
19
Estimate
of Resi-
dent!' al
Contribu-
tion
(lb/d)
1 ,440
640
640
1 ,680
128
Other Indus-
tries, Urban
Storm water,
Percent-
age of
Total
38
27
34
16
38
and Other
Contribu-
tions
(lb/d)
1 ,770
1,350
220
7,930
148
Percent
age of
total
46
58
12
76
43

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        TABLE  10 .   SUMMARY  OF THE CONCENTRATION RANGES OF
        BIOLOGICAL  CONTAMINANTS FOUND IN WASTEWATER INPUTS
	TO MUNICIPAL TREATMENT SYSTEMS*	

 Contaminant                      Range/100 mi

 Total  coliforms                 1 x 106 to 4.6 x 107

 Fecal  coliforms                 3.4 x 105 to 4.9 x 107

 Fecal  streptococci               6.4 x 104 to 4.5 x 106

 Virus                            5 to 100,000 virus units/£

 *As  reported  in the literature reviewed.

     Pound and  Crites  (526) reported  that  raw  municipal sewage
 contains  from 106 to 108  total  coliforms  and from  480  to  1,677
 plaque-forming  units (pfu)/£  of  enteric  viruses.   The  average
 enteric virus density  in  domestic  sewage  reported  by the  ASCE
 (198)  was approximatelv 500 virus  units/100  m£.  Coliform  densi-
 ties averaged 4.6 x  lO'/lOO ml.   Analyses  of wastewater reported
 by Kampelmacher and  Jansen  (339)  show that salmonella  is  regu-
 larly  present.

     Viral concentrations in  raw wastewater  reported by Foster
 and  Engelbrecht (223)  range from 5  to 100,000  viral  pfu/£, with
 reported  seasonal variations  of  a  mean  of  4,000 pfu/£  during warm
 months  and a mean of 200  pfu/£ during cold months.   However, no
 universal procedure  or system is presently available for  culti-
 vation  of all viruses.  It  is likely, therefore, that  many of
 the  investigations  of  virus density in  wastewater  have not
 included  all viruses present  due to the  selectivity  of techniques
 employed.

     Fecal streptococci contaminants  present in the  domestic
 wastewater of seven  communities  were  studied by Geldreich  and
 Kenner  (236).   Figures obtained  from  this  study are  presented  in
 Table  11.
                                19

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                                 TABLE  11.   DISTRIBUTION OF FECAL  STREPTOCOCCI
                               IN DOMESTIC WASTEWATER AND STORMWATER  RUNOFFS  (236)
ro
o
Densities/100 ml
Water Source
Domestic wastewater
Preston, Ida.
Fargo, N. D.
Moorehead, Minn.
Cincinnati, Ohio
Lawrence, Mass.
Monroe, Mich.
Denver, Colo.
Storm water
Business district
Residential
Rural
Fecal
Col 1 forms

340,000
1,300,000
1,600,000
10,900,000
17,900,000
19,200,000
49,000,000

13.000
6,500
2,700
FecaV
Streptococci

64,000
290,000
330,000
2,470.000
4,500,000
700,000
2,900.000

51,000
150,000
58,000
Ratio
FC/FS

5.3
4.5
4.9
4.4
4.0
27.9
16.9

0.26
0.04
0.05
Occurrence
Total
Strains Entero-
Examlned cocci

39
50
50
428
50
70
70

1,476
1,158
445

79.5
100.0
90.0
71.5
84.0
78.6
85.7

78.5
80.0
87.4
S.bovLd
S.eqiumA

None
None
10.0
2.8
4.0
1.4
11,4

1.6
0.5
0.5
(*)

S^aecott*
Atypical JUqiu.-
S.&ae.caJLu> ia.CA.tni>

None
None
None
1.6
None
4.3
2.9

1.2
1.4
0.2

20.5
None
None
24.1
12.0
15.7
None

18.8
18.1
11.9

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                            SECTION  3

                        PRIMARY  TREATMENT
INTRODUCTION
     Primary treatment is intended to physically remove settle-
able solids and most of the discrete suspended and floating
solids from the municipal wastewater stream preparatory to
secondary treatment.  In addition, primary treatment removes a
limited portion of the soluble constituents.

     In primary treatment, the wastewater influent is divided
into three output pathways:  primary effluent, primary sludge
(including grit, screenings, and precipitated matter), and
aerosols.  Effluent from primary treatment can be directly
discharged (until  1977), discharged after disinfection (again
until 1977), or treated by a secondary process.  Primary sludge
is normally subject to additional processing.  At some ocean
coastal sites, however, the sludge is discharged without further
treatment.  Aerosols are rarely a problem, due to the absence
of excessive turbulence.

     The information reviewed during this study is tabulated in
Table 12.  Most research conducted to date concerns the removal
by primary treatment of water quality parameter constituents.
It is only in recent years that researchers have examined the
effect of primary treatment on various public health impairing
contaminants.

WATER QUALITY PARAMETERS

     For several decades, extensive work has been reported con-
cerning general contaminant removal efficiencies for primary
treatment.  Removal  varies widely, depending upon the physical
and chemical characteristics of the wastewater, the proportion
of settleable solids, concentrations of the solids, and deten-
tion time.  Mitchell (453) reported general performance efficien-
cies that  could be expected for typical primary treatment.
Removals achieved  during a three-year study of an operational
primary treatment  system are shown in Table 13.
                               21

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            TABLE 12.   LITERATURE REVIEWED PERTAINING
                  TO PRIMARY WASTEWATER TREATMENT
 Contaminant	Reference Number	
 Water Quality Parameters
  Ammonia                453
  BOD                    206, 318, 453, 654, 665, 707
  COD                    251, 318, 443, 453, 665
  Oil  and  grease         251, 453
  Phosphates             443
  Suspended solids       206, 251, 318, 368, 443, 453, 665,  707
  Total organic
  carbon                 251
  Other (general)        280, 318
 Elemental Contaminants
  Arsenic                453
  Cadmium                124, 453, 507
  Copper                 124, 443, 453, 507
  Iron                   124, 443
  Lead                   124, 453, 507
  Mercury                124, 453
  Nickel                 124, 453, 507
  Selenium               529
  Zinc                   124, 443, 453, 507
Biological Contaminants
  Coliforms              88, 251, 293, 357, 443, 583, 594
                                22

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TABLE 12 (continued)
Contaminant	Reference	
  Coxsackie virus       88
  (A & B)
  Escherichia coli       293,  443
  Fecal  streptococci     293
  Hepatitis virus       586
  Mycobacterium         88, 223
  Parasitic worms       88, 217, 223
  Polio  virus           51, 88
  Protozoa              88, 223
  Salmonella            88, 217, 223,  293,  586
  Shigella              88, 586
  Vibrio cholerae       88
  Virus                  38, 48, 49,  50,  51,  54,  55,  88,  200,
                        223,  242,  487,  583
  Other  (general)       88, 586
                               23

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      TABLE 13.  PRIMARY SETTLING TANK PERFORMANCE (453)


Parameter
COD
BOD5
Suspended Sol i ds
Oil and Grease
Ammonia Nitrogen
Primary
Influent
(mg/£)
539
269
279
72
34
Primary
Effluent
(mg/£)
315
165
103
28
20

Percent
Removal
42
39
64
61
41
     When used as a coagulant during primary treatment, lime is
most effective in reducing certain water quality parameter con-
stituents.  When lime addition of 350 mg/l was followed by air
flotation, Mennell et al .  (443) reported the following removals:
turbidity, 98.5 percent; suspended solids,  95 percent;  COD,  60
percent; and total phosphorus, 99 percent.   Total  nitrogen
removal varied between 10  and 20 percent.  Lower lime dosages
provided proportionally lower removal percentages.  The practice
of dosing primary clarifiers with chemical  coagulants will
probably increase, as municipalities attempt to cost effectively
meet federal and state water quality standards.

ELEMENTAL CONTAMINANTS

     Recent interest in elemental contaminants, particularly
trace metals, has prompted investigation into the  partitioning
of these contaminants in the wastewater treatment  stream.
Primary treatment receives elemental contaminants  in a variety
of forms, e.g., soluble, insoluble,  and complexed.  The con-
centrations of each form vary intrinsically as a complex
function of such factors as influent metal  concentration,  pH,
and ligand concentration.

     Mitchell (453) reported removal efficiencies  for primary
settling over a three-year period at the Hyperion  treatment
plant, Los Angeles, California,as shown in  Table 14.
TABLE 14.  PRIMARY TREATMENT REMOVAL OF METAL ELEMENTS (453)

Copper
Zinc
Nickel
Lead
Arsenic
Cadmium
Chromi urn
Primary
Influent(mg/£)
0.39
0.66
0.30
0.30
0.015
0.01
0.55
Primary
Effluent(mg/£)
0.25
0.42
0.24
0.7
0.017
0.02
0.37
Percent
Removal
36
36
20
—

—
32
                               24

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No
inc
explanation was offered to account for the  anomaly  of
reased lead, arsenic,  and cadmium concentrations.
     Chen and Lockwood (124), also working with the Hyperion treatment
plant, discussed the partitioning of trace metals with particu-
lates as a function of particle size.  It was reported that in
primary effluent, more than 70 percent of the total  trace metals
content is associated with particulates as opposed to the solu-
ble ionic form.  However, only 10 to 20 percent of the Ni, Pb,
andMn was associated with the particulate fraction.   Similar
concentrations of metals were found on the larger (44 ym) and
the smaller (0.2 ym) particles.  However, particles  as large as
44 pm will settle about 200 times as. rapidly as 3-ym particles.
More efficient removals of elemental contaminants could be
expected by the use of either increased wastewater detention
time, or chemical precipitants (e.g., lime) for particle coagu-
lation.  Trace metal removals reported (443) at a lime dose of
388 mg/l approached 100 percent for chromium and copper, 97
percent for iron, and 94 percent for zinc.  Molybdenum was not
effectively removed by this treatment.

BIOLOGICAL CONTAMINANTS

     Primary sedimentation usually removes less than 50 percent
of coliform and pathogenic bacteria from sewage and  is rela-
tively ineffective in removing viruses and protozoa.  Literature
concerning the removal of water-borne pathogens by primary
treatment processes reports a varying degree of efficiency,
depending in part on the type of pathogen studied.  Table 15
highlights the results of Bryan's  investigation  of pathogen
survival  during primary treatment  (88).

     In their literature review, Foster and Englebrecht (223)
reported isolation of salmonella from six of seven different
primary effluent samples.  The raw sludge also contained members
of this genus, with 19 of 20 samples tested as positive for
salmonella organisms.   Tubercle bacilli were reduced about 50
percent in the wastewater stream during sedimentation.  It was
concluded that bacterial  pathogens are ineffectively removed
from wastewater by primary settling; furthermore, the process
produced a sludge that, without further treatment, constitutes
a health hazard.

     Amoebic cysts and parasitic worm ova are also ineffectively
removed by primary treatment, due to their low specific densities
and resulting buoyancy.  Ascaris ova are an exception:  Foster
and Engelbrecht (223)  reported 100 percent settlement of these
ova into the sludge within 15 min.

     Viruses, because of their size (.02 to .3 ym),  are rarely
removed by sedimentation, except for those that are  associated
with wastewater solids.  The nature of the surface chemistry of

                               25

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     TABLE  15.  SURVIVAL OF PATHOGENS
    DURING PRIMARY TREATMENT ( 88, 223)
Pathogen
     % Removal
Salmonella typhi
Salmonella  spp.
Streptococcus faecalis
Mycobacterium
Enteroviruses
Polio viruses
Coxsackie viruses
Amoebic cysts
Parasitic worm ova
Ascar is ova
         >50
        0-15
         <50
        48-57
    no reduction
    no reduction
         <50
no effective removal
        50-98 (223)
no effective removal  (88)
          100
                     26

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viral units suggests that adsorption depends strongly on the
chemical environment, would be expected to vary according to
changes in input water chemistry, and would possibly be affected
by chemical additions.

     The removal of viruses by primary settling has been both
researched and reviewed extensively by Berg (  47,  49,  51,  54).
Berg described a project (49) in which only one to two-thirds
of the viral  particles had settled out in one  day, although 75
percent of the suspended solids had settled.  In this review,
Berg discussed several additional studies on viral removal by
primary treatment; all failed to mention detention time, and
more importantly, the levels of virus in the incoming sewage
were not related to those in the effluent.

     Although primary settling alone will not  effectively reduce
the pathogen content of wastewater, dosing primary settling tanks
with chemical coagulants does show some promise in this regard.
Chemical precipitation, when used during primary treatment, is
capable of removing as much as 99.99 percent of the virus sus-
pended in water, effected through the formation of a coagulant-
cation-virus complex.  Elevated pH levels attained during lime
treatment also result in substantial reductions in viral numbers
(242).  Lime coagulation during primary treatment brings remark-
able reductions of coliform density as well.  A 99.9 percent
coliform reduction was measured at a lime dose of 450 mg/£ (443).
                               27

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                            SECTION 4

             SECONDARY TREATMENT:   ACTIVATED SLUDGE
INTRODUCTION
     The activated sludge process entails  the  growth  of micro-
organisms in a reactor.   This effects partial  biological
degradation of organic compounds in wastewater to simpler
organic compounds, carbon dioxide, water,  microorganisms, and
energy (206).  The basic process requires  two equipment compo-
nents:  aeration tanks and clarifiers.  Active biological sludge
is separated from the effluent in a clarifier and recycled to an
aeration tank.

     Activated sludge, the most popular wastewater secondary
treatment process, has been extensively studied, as indicated
by Table  16.  Most research has focused on water quality
parameters such as BOD,  COD, and suspended solids.  The data
are usually presented as percent removal,  with removal effi-
ciency determined by difference in influent and effluent con-
centrations.  Removal of a specific contaminant can be
accomplished by separation into the sludge or by degradation
through biological activity.  Aerosol generation from the
aeration tank is also a possible contaminant pathway.

     In view of possible health effects, the difference between
separation and degradation can be significant.  If the treatment
process merely partitions a particular contaminant into the
sludge or air, it remains available for migration back to man.
In contrast, biological  degradation can terminate the contami-
nant pathway or transform the potentially  harmful substance into
a nontoxic form.  The separation and degradation components of
the removal  process are often not distinguished in the activated
sludge literature.

WATER QUALITY PARAMETERS

     Past research on activated sludge processes has concen-
trated on water quality parameters, with primary emphasis on
BOD,  COD, and suspended  solids.  Because of the tremendous
volume of literature associated with BOD and suspended solids,
and the absence of direct health effects from these pollutants,
this  report  placed greater emphasis on literature dealing with

                               28

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          TABLE 16.   LITERATURE REVIEWED PERTAINING
                     TO ACTIVATED SLUDGE
Contaminant
           Reference Number
Water Quality Parameters

  Ammonia



  BOD
  COD


  Chlorides

  Cyanides

  Fluorides

  Nitrates


  Nitrites

  Oil and grease

  Phosphates



  Suspended solids


  Total  dissolved
  solids

  Total  organic
  carbon

  Other  (general)

Elemental Contaminants

  Alumi num
3, 7, 24, 27, 61,  103, 150,  184,  185,
190, 203, 233, 310,  314, 389,  453,
530, 620, 630

2, 7, 61, 77, 103, 108,  147, 185, 190,
289, 310, 320, 368,  389, 398,  425,
430, 453, 485, 516,  574, 622,  635,  665,
690

103, 155, 190, 289,  301, 320,  338,
389, 453, 516, 543,  620, 690

62, 403, 446, 506

320, 405, 453, 506

506

7, 24, 27, 61, 67, 185,  190, 195, 231,
233, 630

7, 67, 185, 233, 630, 702

393, 453, 506,702

7, 10, 26, 27, 61 , 62, 103,  150,  185,
190, 195, 215, 233,  269, 301 ,  310,
376, 398, 446, 453,  567, 622,  625,  628

2, 7, 61, 77, 103, 123,  185, 289, 320,
336, 368, 453, 516,  665, 702
103, 147, 185, 263, 446


7, 61 ,  62, 185, 311 ,  543, 620, 702

203, 205, 206, 280, 302, 318,  606, 620



269, 398, 486
                              29

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TABLE 16  (continued)
Contaminant	Reference Number	
Elemental  Contaminants
  Arsenic               506
  Barium                506
  Boron                 185, 446, 506
  Cadmium               123, 124, 125, 453, 471, 476, 486,
                        506, 507, 615
  Chromium              31, 33, 123, 124, 320, 453, 456, 462,
                        471 , 506, 615
  Cobalt                186, 471
  Copper                31, 33, 123, 124, 125, 320, 430, 453,
                        471, 486, 506, 507, 615
  Iron                  123, 124, 186, 471, 486, 506, 615
  Lead                  123, 124, 125, 453, 471, 486, 506,
                        507, 615
  Manganese             123, 124, 215, 47.1, 506, 615
  Mercury               123, 124, 245, 471, 476, 486, 506
  Molybdenum            615
  Nickel                 31, 33, 123, 125, 320, 453, 471, 615
  Selenium              506
  Zinc                  31, 33, 123, 124, 453, 486, 506, 507
  Other (general)        506, 615
Biocidal Contaminants
  Aldrin                 186
  DDT                    690
Synthetic/Organic
 Contaminants	41 0 , 666	
                               30

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 TABLE  16  (continued)
Contaminant	Reference Number	
 Biological Contaminants
   Bacteria               38,  88,  347,  528
   Cl ostrich'urn
   botuli num              311
   Clostridium  perfringens 311
   Coliforms              61,  293,  311,  472,  516
   Coxsackie  virus        51,  88,  439
   (A  &  B)
   Escherichia  coli       293
   Fecal  streptococci     293,  311,  528
   Mycobacterium          223,  293,  311
   Parasitic  worms        88,  223
   Polio  virus            51,  53,  88, 411, 412, 439
   Protozoa               223
   Salmonella             88,  104,  223,  293,  311, 357
   Shigella               88,  293,  311
   Vibrio  cholerae        88
   Virus                  38,  48,  49, 50,  54,  88, 185, 198, 200,
                         210,  223,  242, 259,  447, 488, 700
   Other  (general)        88,  280,  318,  690
                                31

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chemical and biological contaminants  of  more  direct public health
concern.

     The various activated sludge processes are all  able to
remove  over 90 percent of the soluble BOD found in wastewater.
Mitchell (453) recorded data on the removals achieved with
activated sludge processes of these and other water quality
contaminants during his study of the Los Angeles Hyperion
Treatment Plant as shown in Table  17.
        TABLE  17.  ACTIVATED SLUDGE TREATMENT POLLUTANT
                 REMOVALS, LOS ANGELES, CA  (453)



COD
BOD5
Suspended Solids
Oil and Grease
Phenol s
Ammonia nitrogen
Phosphorus
Cyanide
Treatment
Influent
(mq/£)
315
165
103
28
0.09
20
10.1
0,30
Treatment
Effluent
(mq/£)
31
9
9
0.5
0.009
9.6
3.3
0.13

Percent
Removal
90
95
91
98
90
52
67
57
A? can be seen from this table, relatively high removals of
most water quality contaminants can be attained in a practical
application over an extended period of time.  These removal
efficiencies are supported by other researchers and reviewers,
including Noland and Birkbeck (485 ), Huang et al. (302), Rickert
and Hunter (543 ), Lindstedt and Bennett (389), and Besik (62 ).

ELEMENTAL CONTAMINANTS

     Although the activated sludge process efficiently removes
biodegradable organic materials, only limited removal  of soluble
elemental contaminants from the wastewater stream can  be
achieved.  The removal of elemental contaminants is governed by
two basic mechanisms:  (1) the precipitation of metal  hydroxides;
and (2) the adsorption of elemental contaminants by the activated
sludge floe.   In either case, the elemental contaminants removed
will be contained in the sludge.

     When suspended solids removals were in the 90 to  95 percent
range, 90 percent of the aluminum, iron, mercury,  lead, and zinc
settled readily with the biofloc, according to Nomura  and Young
(486).  Chromium (VI) and nickel median removals of 77 percent
and 50 percent, respectively, were recorded under the  same


                              32

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conditions.   Morgan (462)  stated  that  the  removal  percentages
for chromium could vary,  depending  upon  the  treatment  process
used.   Chromium exists in  sewer systems  in  Cr  (III)  and  Cr  (VI);
concentrations depend upon pH.   Cr  (III)  is  readily  adsorbed on
particles or precipitated  as  Cr(OH)3.   Chromium  entering  as
Cr (VI) experiences a strongly reducing environment (little or
no dissolved Oo) in sewers and treatment plants, and is  thus
reduced to Cr (HI) and either precipitated or adsorbed.   Aera-
tion used in activated sludge or stabilization processes can
cause the resolubilization by oxidation of trivalent to  hexava-
lent chromium, with resulting effluent water degradation.

     The association of trace metals with suspended solids during
the activated sludge process was investigated by Chen and
Hendricks (123) and Chen and Lockwood (124) at the Hyperion
                  Their work confirms that many trace metals are
                suspended solids, although the concentration of
                particles does'not appear to depend significantly
                   Rather, the removal of trace metals from the
Treatment Plant.
associated with
trace metals on
on particle size
waste stream by activated sludge processes depends to a great
extent upon the adsorptive capability of the activated floes.

     Mitchell  (453) has recorded elemental removal efficiencies
for the Hyperion Plant over a three-year period, as shown in
Table  18.
              TABLE 18 .   REMOVALS OF TRACE METALS
                 BY ACTIVATED SLUDGE PROCESSES,
                      LOS ANGELES, CA (453)
El ement
Copper
Zinc
Silver
Nickel
Lead
Arsenic
Cadmium
Chromium
Influent
(mg/£)
0.25
0.42
0.019
0.24
0.07
0.017
0.02
0.37
Effluent
(mgAO
0.08
0.23
0.012
0.15
0.08
0.013
0.013
0.013
Percent
Removal
68
46
37
38
--
24
35
96
These figures can be compared with the removal  percentages
assembled by the state of California  as shown  in  Table  19.
Clearly, the activated sludge process can reduce,  but will  not
eliminate,  trace metal concentrations in the municipal  waste-
water stream.
                               33

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          TABLE   19.   PERCENT  REMOVALS  OF TRACE METALS BY
                THE  ACTIVATED  SLUDGE  PROCESS  ( 615)

                                     Average
	 Element	Percent Removal	

           Cadmium                       56
           Chromium                      36
           Copper                       59
           Iron                          48
           Lead                          48
           Manganese                    22
           Molybdenum                    23
           Nickel                        22
           Silver                       71
	    Zinc	60	


 SYNTHETIC/ORGANIC CONTAMINANTS

      Malaney  et al.  (410) in a study of the removal  of  possible
 carcinogenic  organic  compounds  by  activated  sludge,  concluded
 that no  significant reduction was  accomplished within normal
 detention times at  the  three  treatment plants  studied.
 Table 20 lists  the  possible carcinogens included in the
 analysis.

      Recent work by Wachinski et al.  (666 )  suggests  that  herbi-
 cide detoxification can be achieved  with  a  pure  oxygen-activated
 sludge treatment system that  was determined  to be  both  economical
 and  ecologically safe.   A  proprietary  strain of  mutant  micro-
 organisms,  PHENOBAC (developed  by  the  Worne  Biochemical  Corp.),
 was  utilized  that was able to degrade  halogenated  phenols.   Even
 with relatively high  herbicide  concentrations  (1380  mg/£),
 degradation of  as much  as  73  percent was  accomplished after  a
 16-day aeration period  using  optimum proportions of  required
 nutrients,  microflora,  and oxygen.   According  to the  authors,
 this figure represents  a conservative  estimate of  possible
 reductions, since testing  was conducted at  18°C, while  the
 optimum  growth  temperature for  PHENOBAC is  close to  30°C.

 BIOLOGICAL  CONTAMINANTS

      Activated  sludge followed  by  secondary  sedimentation  can
 remove over 90  percent  of  coliform or  pathogenic bacteria  that
 remain after  primary  sedimentation;  other  biological  pathogens
 are  removed to  varying  degrees.  Nonetheless,  even  with 90
 percent  removal,  appreciable  amounts of pathogens  remain present
 in  the effluent.
                               34

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   TABLE  20 .   POSSIBLE CARCINOGENS
    INCLUDED IN THE ANALYSIS (410)
2,3 - Butylene oxide
B - Propiolactone
Thiourea
Ethycarbamate
2 - Thiouracil
4 - Ethoxyphenylurea
Benzidine
4,4'  - Dihydroxy-a,b-diethylstilbene
2 - Naphthylamine
4,4'  - Bis (dimethylamino) benzopheuone
p-Phenylazophenol
p-Phenylazoani1ine
9,10 - Dimethylanthracene
1,2 - Benzanthracene
7 - Methyl-1,2-benzanthracene
9,10 - Dimethyl-1,2-benzathracene
1,2,5,6 - Dibenzanthracene
3/4 - Benzpyrene
1,2,4,5 - Dibenzpyrene
20 - Methylcholanthrene
2 - Nitrofluorene
2 - Fluoreneamino
N-2 - Fluorenylacetamide
7,9 - Dimethylbenz (c) acridine
7,10 - Dimethylbenz (c) acridine
Dibenz (a,h)  acridine
Dibenz (a,j)  acridine
                35

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     Pathogens can either be removed by adsorption onto the
sludge floes or destroyed by the predatory activity of the
zoogleal component.  A review of the literature (280,  318)
reveals discussion of general wastewater removal  rates with
little differentiation between removals and the biocidal  prop-
erties of activated sludge.

     Foster and Engelbrecht (223) provided a review of pathogen
removal by activated sludge processes.   Conclusions of this
review are summarized in Table  21.


               TABLE  21.  REMOVAL OF PATHOGENS BY
               THE ACTIVATED SLUDGE  PROCESS (223)
     Pathogen	Percent Removal
     Salmonella                 96 to 99
     Mycobacterium              Slight to 87
     Amoebic cysts              No apparent removal
     Helminth ova               No apparent removal
     Virus                      76 to 99
     Ova of intestinal parasites are apparently unaffected by
the activated sludge process; in fact, the literature indicates
that activated sludge-mixed liquor provides an excellent hatch-
ing medium for eggs.

     A review by Hunter and Kotalik (311) provided additional
pathogen removal data, as summarized in Table  22.


     TABLE  22.   PERCENT REMOVALS OF BIOLOGICAL PATHOGENS BY
                   THE ACTIVATED SLUDGE PROCESS (311)

     Pathogen	Percent Removal
Col if orm
Fecal streptococci
Shigel la
Salmonel la
Pseudomonas aerogjnosa
Clostridium perfringens
Mycobacterium tuberculosis

90
84
90
70
99
90
66
to
to
to
to
to
99
94
99
99
88
     A list of the species of protozoans,  nematodes,  and  fungi
that have been found in activated sludge effluent was also
presented by the authors.  Species recorded include:
                               36

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     Protozoa -
                                     Fungi  -
     Amoeba sp.
     Epistylis p 1 i c i a t i 1 s
     Euplotes patella
     Loxophyl1 urn helus
     Oikornonas sp.
     Pelodinium rem'forme
     Phyllomitus anylophagus
     Trigonomonas  compressar
     Vorticel1 a campanula

     Nematodes -

     Dory!aimus
     Monhystera
     Rhabdias
                                     Alternaria
                                     Aspergi11 us
                                     Aureobasidium
                                     Candida
                                     Cryptococcus
                                     Fusarium
                                     Fusarium aquaeductum
                                     Fusarium oxysporum
                                     Fusarium roseum
                                     Geotrichum
                                     Hansenula
                                     Kloeckera
                                     Mucqr
                                     Pemci 111 urn
     	                        Rhodotorula
                                     Saccharomyces
                                     Torul opsi s
                                     Trichoderma
                                     Trichosporon

     The removal of viral contaminants by activated sludge has
recently become the topic of considerable research.   In general,
viral removal of up to 90 percent has been observed after the
activated sludge process.  However, large variations  in removal
have been reported, probably because sampling was not temporally
coordinated  (242).   Destruction by sewage microflora  and virus
adsorption to floe during the process are believed to be the
main factors governing viral removal.  Table 23  reports typical
viral removals that can be expected from  activated sludge
treatment ( 88 ).


     TABLE  23.  VIRAL REMOVAL BY ACTIVATED SLUDGE TREATMENT (88)
     Pathoqen
                                Percent Removal
     Enterqv iruses
     Polio viruses
     Coxsackie viruses
     ECHO viruses
                                0 to 90 percent
                                0 to 90 percent
                                0 to 50 percent
                                no apparent removal
     Malina et al.  (411) concluded from their research that
viral inactivation by activated sludge is independent of the
hydraulic detention time.  Polio virus adsorption to sludge is
almost immediate; the adsorbed virus particles are inactivated
according to first order kinetics with a half-life in the range
of 4 to 5 hr .   Activated sludge utilizes aeration for optimum
dispersion of the flocculant masses which, along with gases
produced during microbial respiration, may entrain bacterial
                               37

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and viral  pathogens in aerosols.  The aerosols released are in
the 5-ym diameter range, small enough to permit lung penetration
of a substantial proportion of the particles.
                              38

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          SECONDARY TREATMENT:  TRICKLING FILTER
INTRODUCTION

     Trickling filters have been widely used for secondary bio-
logical treatment of municipal wastewater, and substantial
literature is available on this process,  as indicated on Table 24


     The trickling filter system generally consists of a tank
open on both top and bottom.  The tank is filled with a rock or
plastic filter media having a high surface area to allow attach-
ment of zoogleal slimes and void fraction for movement and dif-
fusion of oxygen.  Contaminant removal is accomplished through
adsorption at the surface of the biological slimes covering the
filter media.  Following adsorption, the organics are utilized
by the slimes for growth and energy.  The trickling filter is
followed by clarification to remove biological solids periodi-
cally flushed from the filter.

     Trickling filter influent is usually from a primary treat-
ment system.  System outputs include effluent, sludge, and pos-
sible aerosols.

     The literature generally refers to percent removal, with
no distinction made between separation and degradation or des-
truction.  As in the case of other secondary processes, the
literature primarily addresses the general and biological con-
taminants and is sparse in the areas of elemental, synthetic,
and biocidal contaminants.

WATER QUALITY PARAMETERS

     The removal of BOD and suspended  solids  by trickling
filters is reported to be from 65 to 95 percent,  averaging
about 85 percent (318, 615).   The efficiency  of trickling
filtration decreases as temperatures fall  below 20°C.   Imhoff
et al . (318) reported that a reduction of temperature  from
20° to 10°C results in an efficiency loss of  about  40  per-
cent.  Nickerson et al . (479) found that chemical addition ahead
of primary clarifiers increases overall BOD and suspended solids
removals in trickling filters.  Lager and Smith (368) reported
that no significant removal of total nitrogen or phosphorus
occurred during the conventional trickling filter process.  In

                               39

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            TABLE 24.  LITERATURE REVIEWED PERTAINING
                      TO TRICKLING FILTERS
Contaminant	Reference Number	
Water Quality Parameters
  Ammonia              4, 20, 183, 368, 440, 653, 685
  BOD                  25, 131, 318, 368, 398, 450, 479,  490,
                       540, 615, 635, 653, 706
  Chlorides            450, 685
  COD                  131, 258, 440, 450, 686
  Nitrates             3, 4, 183, 368, 440, 685
  Nitrites             183, 440, 685
  Phosphates           32, 324, 368, 398, 440, 490, 685
  Suspended solids     261, 318, 368, 479, 490, 615, 653,  706
  Total  organic        25, 131, 311
  carbon
  Other  (general)      205, 206, 280, 318
Elemental Contaminants
  Aluminum             398
  Boron                 685
  Cadmium              615
  Chromium             31, 540, 615
  Copper               31, 540, 615
  Germanium            655
  Iron                 615, 685
  Lead                 615, 685
  Manganese            615, 68&
  Molybdenum           615
                               40

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TABLE 24 (continued)
Contaminant                       Reference  Number	
  Nickel                31,  431,  540,  615
  Zinc                  31,  540,  615
Synthetic/Organic
 Contaminants             131,  311
Biological  Contaminants
  Bacteria              38,  76,  88,  210, 254
  Coliforms             254,  293,  472, 592
  Coxsackie virus       88
  (A & B)
  Escherichia  coli      293
  Fecal streptococci    592
  Mycobacterium         223
  Parasitic worms       88,  223,  311
  Polio virus           88
  Protozoa              223
  Salmonella            88,  223,  357,  592
  Shigella              88
  Vibrio  cholerae       88,  357
  Virus                 38,  49,  50,  51, 54, 88, 198, 224, 259,
                        592
  Other (general)       88,  254,  318
                                41

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low-rate filters, ammonia and nitrogenous  organic  compounds are
usually oxidized to yield high proportions of  nitrates  and some
nitrites in the effluent; high-rate trickling  filter  effluents
are low in nitrates and nitrites due to  limited  system  oxidation.
Barth et al.  (32) reported total phosphorus  removals  of up to
75 percent with direct dosing of aluminate to a trickling filter

ELEMENTAL CONTAMINANTS

     Removal of elemental contaminants by trickling  filters is
not well documented.  A  summary of the literature on  metal
removals is shown  in Table  25 •
      TABLE  25.  TRICKLING FILTER PROCESS REMOVAL
             OF TRACE METAL CONTAMINANTS (615 )

                                           Average
          Element                       Percent Removal

          Cadmium                              5
          Chromium                            19
          Copper                              47
          Iron                                46
          Lead                                36
          Manganese                           16
          Molybdenum                          15
          Nickel                              20
          Silver                              48
          Zinc                                56
Trace metal removals by trickling filters are substantially
lower than those achieved with the activated sludge process be-
cause there is less formation and sedimentation of trace metal
complexes.

BIOLOGICAL CONTAMINANTS

     Trickling filters do not effectively remove many biological
pathogens.  Table 26  illustrates  reported  removal  efficiencies.
Organisms are  adsorbed  into  the  zoogleal  slime  but  due to
similar surface charges and  morphology,  biocidal effects are
variable (318).
                               42

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           TABLE 26.   REMOVAL OF PATHOGENS BY
                  TRICKLING FILTERS (223)
           Pathogen Group              Efficiency
Salmonel 1 a
Mycobacterium
Amoebic Cysts
Helminth Ova
Virus
88
66
11
62
0
to
to
to
to
to
99
99
99
76
84
.9
.9
Literature by Foster and Engelbrecht (223) revealed that trick-
ling filters are capable of reducing paratyphoid organisms by
84 to 99 percent.   A review by Hunter  and  Kotalik  (311)  showed
99.7 percent removal of Schistosoma  mansoni  ova.   These  authors
also concluded that trick!ing  filter effluents  can contribute a
major portion of the free living nematode population found in
receiving waters.

     Improperly operated low-rate trickling filters can provide
an excellent breeding area for insects, especially filter flies
(psychoda) and springtails.  Trickling filters cannot be depen-
ded upon to produce significant or consistent viral reductions.
Foster and Engelbrecht (223) reported removals ranging  from 0
to 84 percent.  Berg (51) speculated that even when viruses are
adsorbed, they may eventually be replaced by other substances
and leach out of the filter slime as a result of  an equilibrium
effect.
                                43

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            SECONDARY TREATMENT:   AERATED  LAGOONS
INTRODUCTION

     Aerated lagoons are aerobic or facultative ponds in which
mechanical aeration is used to increase the rate at which oxy-
gen is made available to facilitate biological  stabilization.
The aeration also provides mixing for suspension of microbial
floe.  The biological process does not include  algae, and organic
stabilization depends on the mixed liquor that  develops within
the pond.  Literature surveyed concerning aerated lagoons is
listed in Table 27.

WATER QUALITY PARAMETERS

     BOD removal by aerated lagoons is a function of aeration
period, temperature, and the nature of the wastewater.   The
aeration of a typical domestic wastewater for five days at 20°C
provides about 85 percent BOD reduction; lowering the temperature
to 10°C reduces the efficiency to approximately 65 percent (280).

BIOLOGICAL CONTAMINANTS

     A discussion of the literature by Parker ( 503 ) revealed
that coliform reductions in the range of 80 to  99 percent can  be
achieved with optimum detention time.  This is  supported by the
experiments of Carpenter et al. (105), who reported that coli-
form organisms are efficiently removed by the use of aerated
lagoons.  Klock (357) stated that the coliform  survival rate
in lagoons is a function of the oxidation-reduction potential
and temperature.

     Berg (49) discussed the removal of viruses by stabilization
ponds, concluding that virus removal can be expected to be
erratic.
                               44

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             TABLE  27.   LITERATURE REVIEWED PERTAINING
                       TO  AERATED LAGOONS
Contaminant
          Reference Number
Water Quality Parameters
  Ammonia
  BOD
  COD
  Ni trates
  Nitrites
  Phosphates
  Suspended solids
  Other  (general)
Biological Contaminants
  Bacteria
  Col iforms
  Escherichia  coli
  Fecal  streptococci
  Salmonel1 a
  Virus
233
47, 252, 280, 332, 386, 654
47, 143, 252
233
233
173, 386
252, 368
206, 280, 318

105, 357
105, 293, 357, 503
503
293, 503
293
49, 105, 200
                                45

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              SECONDARY TREATMENT:  PONDING
INTRODUCTION
     An oxidation or facultative pond is generally a shallow
earthen basin designed to promote a symbiotic existence between
algae and bacteria (368).  Algal photosynthesis and surface
reaction maintain aerobic conditions in the photic region, while
anaerobic bacteria flourish in the aphotic zone.  Ponds are
normally operated in series and are sometimes used for
"polishing" effluent from conventional secondary processes.

     Influent to a ponding system may be raw sanitary waste,
primary effluent, or secondary effluent.  Pond effluent can
enter the environment by direct discharge or by seepage to the
groundwater. Literature reviewed concerning ponding is listed
in Table 28; as can be seen from this review, only a limited
amount of research has examined the removal of contaminants by
the ponding process.

WATER QUALITY PARAMETERS

     Oxidation pond removal efficiencies for suspended solids
and BOD can vary widely and may even reach negative values
(368).  Removal ranges of 60 to 50 percent have been reported
for suspended solids, and of 70 to 10 percent for BODg.  This
variation occurs because most influent BOD is converted into
suspended algal mass.  This mass exerts a BOD demand and provides
suspended solids that may be carried out in the effluent.

     Bacterial  decomposition and algal growth are both retarded,
reducing removal efficiency of the ponding process, by reduced
temperatures (280).

SYNTHETIC/ORGANIC CONTAMINANTS

     The removal of trisodium nitrilotriacetate (NTA) by ponding
has been investigated by Klein (356).  He found that after a
two-month acclimation period, steady-state removal was in excess
of 90 percent,  with influent concentrations in the range of
30 mg/£.
                              46

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     TABLE 28.  LITERATURE  REVIEWED  PERTAINING TO PONDING

Contaminant	Reference Number	
Water Quality Parameters
  BOD                         172,  280,  368
  COD                         685
  hlorides                    222
  Fluorides                   222
  Nitrates                    122,  172,  195,  230, 663
  Phosphates                  172,  195,  221,  230, 685, 693
  Suspended solids            206,  368
  Other (general)             206,  280,  368
Synthetic/Organic
 Contaminants                   356
Biological  Contaminants
  Bacteria                    413,  592
  Coliforms                   417,  480,  592
  Escherichia col i            418,  500
  Fecal streptococci          417,  418,  592
  Salmonella                  337
  Virus                       49,  50, 51, 592
                               47

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BIOLOGICAL CONTAMINANTS

     Kampelmacher and Jansen (337) found that removal  of
salmonella by oxidation ponds was not inferior to removal
achieved by conventional treatment plants.   Species of the
coliform group, although reduced by ponding, are not effectively
eliminated according to Parhad and Rao (500).  Slanetz et al.
(592),  however, reported that if two ponds  were operated in a
series  at temperatures of 17° to 26°C, the  die-off rate of
coliform, fecal coliforms,  and fecal streptococci ranged from
95 to 99 percent.   During winter when temperatures were in the
1   to IOC range,  the die-off rate was 46 times lower.  Berg
(  51 ) states that virus removal  by ponding  is erratic, ranging
from 0  to 96 percent; virus recovery decreased as the  effluent
passed  through a series of  maturation lagoons.
                               48

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                           SECTION 5

                TERTIARY TREATMENT:  FILTRATION
INTRODUCTION
     Inability of gravity sedimentation in secondary  clarifiers
to remove small  particles (and associated public health  impair-
ing contaminants) is a limitation of BOD and  suspended  solids
removal by conventional  wastewater treatment.   Filtration as  a
tertiary process upgrades treatment performance by  removing  a
portion of the unsettled suspended solids from secondary efflu-
ents.  In addition, filtration often precedes  other tertiary
processes such as adsorption and ion exchange  since the  pre-
sence of suspended solids interferes with the  operation  of
these processes.

     Filtration  of wastewater to reduce the suspended solids
concentration is accomplished by passage through a  bed  of gran-
ular particles.   Single, dual, or mixed media  beds may be used,
composed of anthracite coal, granite, sand, and/or  gravel
(280).  Suspended solids are removed by a variety of  mecha-
nisms:  straining, impingement, settling, and  adhesion.   The
treatment efficiency of the process is influenced by:

     •  The concentration and characteristics  of the  wastewater
        solids (particle-size distribution, surface character-
        istics,  organic versus inorganic, etc.);

     •  The characteristics of the filter media and  filtering
        aids used (particle-size distribution, surface  charac-
        teri sties , etc.);

     •  The design and operation of the filter.

Since wastewater flow rate and solids content  are variable,  and
processes upstream of filtration may vary in  performance, the
efficiency of filtration may also be expected  to vary.   For
this reason, values presented in the following discussion
should be considered as merely indicative of  the range  of
achievable removals.
                               49

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     TABLE 29.  LITERATURE REVIEWED PERTAINING TO FILTRATION

Contaminant	Reference Number	
Water Quality Parameters
  Ammonia              21, 287, 438, 615, 706
  BOD                  64, 166, 348, 377, 438, 611, 615,  649,
                       706
  COD                  64, 377, 438, 611, 615
  Chlorides            62, 438, 506, 611, 638
  Cyanides             506
  Fluorides            506
  Nitrates             202, 438, 611, 638
  Oil & grease         506
  Phosphates           59, 64,  166, 335, 438,  615,  649
  Suspended solids     19, 59,  233, 280, 335,  377,  615,  638,  649,
                       670, 706
  Total dissolved      506
  solids
  Total organic        62, 64,  615
  carbon
  Other (general)      203, 280, 318
Elemental Contaminants
  Arsenic              506> 576
  Barium               506
  Boron                506
  Cadmium              18, 19,  391, 506, 507,  714
  Chromium             18, 19,  391, 506, 714
  Copper               18, 19,  348, 506, 507,  611,  714
  Iron                 18, 506, 611, 714
                                50

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TABLE 29 (continued)
Contaminant	Reference  Number
  Lead                  506,  507,  714
  Manganese             18, 325,  506,  611,  714
  Mercury               506
  Nickel                18, 506,  507
  Selenium              18, 391,  506
  Zinc                  18, 348,  506,  507,  611,  714
  Other                 18, 506
Synthetic/Organic          5nfi   fiqi
 /•»  •  •   .               iJ\J\j+\Jj\
 Contaminants
Biological Contaminants
  Bacteria              88, 176
  Coliforms             55, 243,  305,  313
  Coxsackie virus       49, 88
  (A & B)
  ECHO virus            560
  Hepatitis virus       243
  Parasitic worms       88, 678
  Polio virus           56, 81, 88,  118,  547,  560, 601
  Salmonella            88
  Shigella              88
  Vibrio cholerae       88, 219
  Virus                 14, 49, 50,  80,  82,  88,  139,  176,  233,
                        242,  259,  305,  487,  574,  608
  Other                 81, 88
                                51

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 WATER QUALITY PARAMETERS

      In general, the best effluent quality  achievable  by plain
 filtration of secondary effluent is about  5 to  10 mg/l for sus-
 pended solids and BOD.   The suspended  solids  content of
 secondary effluent was  reduced  to  5 mg with both rapid sand and
 mixed media  filters, employed respectively at a treatment and a
 pilot plant.  Complete  removal,  however, could not be effected
 If further reduction is desired, chemical  coagulation must
 precede filtration (233, 280).

      Two studies  (615)  indicated that essentially
 complete suspended solids removal was accomplished  at both a
 pilot facility and a major treatment plant when filtration was
 preceded by chemical treatment of secondary effluent.   Filter
 effluent contained 3 mg/l BOD and 25 mg/t  COD.   Chemical  clari-
 fier effluent contained 0.7 mg/l total phosphorus;  after  fil-
 tration, this phosphorus content was reduced to 0.1  mg/£  .  At
 the pilot facility,  the filter effluent contained 17.6 mg/l
 COD,  9  mg/£ total organic carbon (TOC), and no  detectable  phos-
 phorus,  compared with filter influent concentrations  of  18.1
 mg/l COD,  8.6 mg/l TOC, and 0.4  mg/l phosphorus.

      When  chemically treated secondary effluent was  applied  to
 rapid-sand  filters,  generally 20 to 60 percent  of applied  BOD
 was removed,  30  to 70 percent of phosphate, and 40  to  80  per-
 cent  of  the  suspended solids (649 ).  These values  were ob-
 tained  using  a  variety  of influent concentrations and  chemical
 dosages.  The results of 30 days continuous operation  of  a
 pilot plant  practicing  filtration preceded  by chemical  treat-
 ment  of  secondary effluent  are summarized  in  Table 30  (615).
   TABLE  30.   RESULTS  OF  ONTARIO,  CANADA  PILOT  PLANT
         STUDY  INVOLVING FILTRATION  PRECEDED  BY
      CHEMICAL  TREATMENT OF  SECONDARY  EFFLUENT (615 )
  Quality Parameter
   KdW
Wastewater
secondary
Effluent
 Filter
Effluent
Total Organic Carbon      110-165
(mg/l)

BOD5 (mg/l)               230-400

P04 (as P04)                9-21

Total Nitrogen N           27-51

Ammonia N                  17-29

Suspended Solids (mg/l)   148-268
                14-28


                 5-14

               1.3-3.5

                25-37

                21-29

                13-37
              4.5-7.5


              2.0-3.0

              0.4-1.0

               20-35

               18-29

                3-12
                              52

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     Results of a pilot  plant  study  at  Cleveland, Ohio - where
chemical  coagulation  and settling  of raw  wastewater was
followed  by filtration and granular carbon adsorption -  were
reviewed  by Gulp and  Shuckrow (151).  On  the basis  of the  data
provided, removals attributable to chemical  treatment and  fil-
tration can be calculated to be 66 percent of the applied  BOD
and 77 percent of the applied COD.  A second pilot  plant study
reviewed  by the authors  involved the same treatment scheme.
Removals  at this plant due to combined chemical  treatment  and
filtration can be inferred to range from  77  to 84 percent.

     While studying soil filtration, de Vries (166) applied
primary effluent to a sand filter and obtained BOD  and phos-
phate removals of nearly 100 percent.  Phosphate removals  were
attributed to the natural coatings of Fe00r>  and Al/,0^ on sand
grains.

ELEMENTAL CONTAMINANTS
Fe2°3
A1203
     After chemical treatment, filtration to remove residual
particulate matter may provide some additional removal of ele-
mental contaminants.  Elemental contaminant removals achieved
by filtration depend primarily upon the extent of suspended
solids removals, with which the various trace elements are
associated.  Table  31, compiled from the literature by Argo
and Culp  (is) gives results for sand filtration of some
municipal and industrial wastes.
  TABLE  31.  HEAVY METAL REMOVAL BY SAND FILTRATION
             FOLLOWING LIME COAGULATION (18)
Metal
Cd

Cr+6
Cr+3
Cu

Fe

Mn

Ni

Se
Concentration
Before Filt.
Trace to
0.00075 mq/i
0.0503
2.7
0.79
-
„.

_

0.08

.0103
Concentration
After Treat.

0.00070
0.049
0.63
0.32
.5
0.1
1.2 Organic
0.1
1.1 Organic
0.1
0.5
0.00932
PH
8.1
7.6.
7.6
8.7
9.5

10.8
10.5
10.8
10.5
8.7
9.5
11
% Removal
By Filt.
95
6.6
2.6
77
59.5







9.5
                               53

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TABLE 31 (continued)
Metal
Ag
Zn
Concentration
Before Filt.
0.00164
0.97
Concentration
After Treat.
0.00145
0.23
2.5
pH
11
8
9


.7
.5
% Remova
By Filt.
11.6
76.3
1


Patterson ( 506 ) cites evidence from pilot plant studies that
little or no additional removal of arsenic was afforded by fil-
tration of chemically treated municipal wastewater.

BIOLOGICAL CONTAMINANTS

     Several investigations have been reported concerning the
removal of viruses by sand filtration.  It has been shown that
insignificant virus removal is achieved by rapid filtration
through clean sand (14, 49).  However, virus removal  efficiency
will be increased by impregnation of the filter medium with
coagulated floe, the presence of organic matter trapped in the
sand, chemical  flocculation prior to filtration, or a decrease
in the filtration rate.  The addition of iron salts prior to
filtration has  resulted in significantly higher coliform reduc-
tions, as discussed by Hunter et al. (313).   Similarly,
Robeck et al. ( 547 ) noted that if a low dose of alum was fed to
a rapid coal and sand filter just ahead of filtration, more
than 98 percent of polio virus  Type I" could be removed.  If the
dosage was increased and conventional f1occulators and settling
were used, removal was increased to over 99 percent.   The
authors also noted a general trend toward better removal of
polio virus I with slower filtration rates although their data
were generally  erratic.  At slow sand filter rates (0.6 to 1.2
 -£/min/m2), removal ranged from 50 percent to about 98 percent.
At rapid filtration rates (38 to 76 £/min/m2), virus  removals
ranged from about 10 to 70 percent.  Similarly, research exam-
ined by Berg (49) showed that filtration through sand at 7.5 If
min/m2 removed  99 percent of the coxsackie virus A5 while fil-
tration at 75 £/min/m2 removed only about 10 percent of the
virus .

     Brown et al. ( 81 ) reported 70 to 90 percent removals of
low concentrations of either bacteriophage T2 or polio virus
Type I by filtration through uncoated diatomaceous earth.
However, no significant virus removals by uncoated diatomaceous
earth were achieved in a laboratory study by Amirhor and
Engelbrecht (14).  With polyelectrolyte-coated filter media,
removals greater than 99 percent were consistently achieved.


                               54

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      In  laboratory  tests  by  Berg et al.  (56), from 82 to
 greater  than  99.8 percent  of polio virus I was removed from
 chemically  treated  effluent  by  rapid  sand filtration.  The
 results  of  these tests  are given in Table 32  .


       TABLE  32 .   REMOVAL OF POLIOVIRUS I FROM.
         Ca(OH)2  FLOCCULATED  EFFLUENT,BY  RAPID
                      SAND  FILTRATION
      AS  MEASURED BY  MEMBRANE FILTER RECOVERY  OF VIRUS  (56 )

	Virus  Concentration pfu/l	


 Test  No.                                       Virus Removal
                                                  percent
               Before  Sand       After  Sand
               Filtrationt      Filtration
1
2
3
4
5
2,200
15,912
1,940
505
47
397
750
<4.6
12.5
2.8
82;0
95.3
>99.8
97.5
94.0
 *  Filtration  rate  2.25  gpm/sq  ft  through  8  in  of  sand.
 t  Virus  concentration  in  flocculated  effluent  just  prior  to
   sand  filtration.


      Laboratory  experiments  on the  removal  of  nematodes by
 rapid sand  filtration  were  conducted  by Wei  et al.  (678 ).
 Removal  efficiency  was  about 96 percent when all  the  nematodes
 in the  influent  were dead or nonmotile.   However, most motile
 nematodes were  able to  penetrate  the  filter  bed.

      Sand filtration may  also  provide some  removal  of amoebic
 cysts and ascaris  eggs, according to  a literature survey  by
 Bryan (88).   He did not  indicate the levels of removal affor-
 ded.
                               55

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                TERTIARY  TREATMENT:  ADSORPTION
INTRODUCTION
     Adsorption refers to the removal  from water or wastewater
streams of dissolved contaminants by their attraction  to  and
accumulation on the surface of an adsorbent substance.  Activa-
ted carbon is the most widely used adsorbent in municipal
wastewater treatment to remove trace organics.   Adsorption
using activated carbon is utilized as  a tertiary treatment
step, usually following sand or multimedia filtration.

     Carbon adsorption systems generally utilize granular or
powdered activated carbon packed in a  column or forming a fil-
ter bed through which wastewater is passed.  Three consecutive
steps occur in the adsorption of wastewater contaminants  by
activated carbon:  (1) the film diffusion phenomenon,  or  the
transport of the adsorbate through a surface film surrounding
the activated carbon; (2) the diffusion of the  adsorbate  within
the pores of the activated carbon; and (3) adsorption  on  the
interior surfaces of the activated carbon.

     Carbon adsorption of contaminants has been the topic of
many research projects as shown in the literature surveyed  for
this report, tabulated in Table  33 .

WATER QUALITY PARAMETERS

     Adsorption is most effective for removing  refractory and
other organics from wastewater.  This  is especially important
when effluents of exceptional quality are required (e.g., for
groundwater recharge or other reuse applications).  Adsorption
can be used either as a polishing step or as the major treat-
ment process (676 ).  Rizzo  and Schade (544)  and Zamtsch and
Morand  ( 712 ) reported that carbon columns alone were capable
of about 85 percent removal of BOD from wastewaters entering
the columns.  Bishop et al. (  64,  68) and Zanitsch and  Morand
( 712 ) reported 75 to 80 percent TOC removals under the  same
conditions.  Weber et al.  ( 676) found that a treatment  system
composed of primary settling, ferric chloride coagulation,  and
carbon adsorption could remove up to 97 percent of the influent
BOD.
                              56

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     TABLE 33.   LITERATURE REVIEWED  PERTAINING  TO  ADSORPTION

Contaminant	Reference  Number	
Water Quality Parameters
  Ammonia                    61,  64,  65,  103, 438
  BOD                        61,  64,  65,  84,  92,  103,  151,  167
                             172, 261,  277,  368,  438,  544,  676,
                             712
  COD                        64,  65,  84,  103, 151, 174,  261,
                             336, 438,  544,  707
  Chlorides                  62,  438, 494,  598
  Nitrates                   61,  64,  65,  172, 676
  Oil and grease             249
  Phosphates                 13,  61,  64,  65,  92,  103,  172,  232,
                             438, 676
  Suspended solids           19,  61,  64,  65,  92,  103,  172,  261,
                             336, 438,  676
  Total dissolved
  solids                     103, 233,  707
  Total organic
  carbon                     61,  62,  64,  65,  68,  167,  277,  518,
                             544, 587,  676,  712
  Other (general)            280, 318
Elemental Contaminants
  Aluminum                   644
  Arsenic                    419, 644
  Barium                     419, 644
  Boron                      538, 644
  Cadmium                    18,  19,  315, 370, 372, 419, 549,
                             644
  Chromium                   18,  19,  303, 315, 370, 372, 419,
                             549, 644
                               57

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TABLE 33  (continued)
Contaminant
        Reference Number
Elemental  Contaminants
  Cobalt
  Copper
  Iron
  Lead
  Manganese
  Mercury
  Nickel
  Selenium
  Zinc
  Other  (general)
Biocidal Contaminants
  Chlorinated
  hydrocarbons
  Dieldrin
  Herbicides
  Other  (general)
Synthetic/Organic
 Contaminants
Biological Contaminants
  Bacteria
  Col iforms
  Escherichia co1i
  Polio virus
  Virus
370, 644
19, 316, 549, 644
316, 370, 644
370, 419, 644
370, 419, 644
370, 394, 419
370, 419, 644
18, 506, 644
316, 419, 644
18, 372


373, 570
278
370, 272, 570
278, 322, 373, 615
67, 167, 233, 249,  278,  322,  332,
373, 422, 541 , 599,  615,  674,  691

154
61
140
118, 240, 241, 601,  609
133, 140, 242, 259,  488,  608,  609
  58

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     There is some disagreement among researchers  regarding the
ability of activated carbon to remove nitrogen  species  from
wastewaters.  Bishop et al. (64) reported that  carbon  adsorption
had little effect on nitrogen concentrations.   On  the  other hand,
Weber et al. (676) found that their primary settling  ferric
chloride coagulation, carbon adsorption system  removed  95  per-
cent of the influent nitrate; the reduction was attributed
partly to biological populations growing in the columns.

     Weber et al . (676 ) reported that their pilot system also
removed 90 percent of the phosphate in the influent wastewater.
However,  much of the research on phosphate adsorption has been
concerned with adsorbents other than carbon.  Gangoli  and
Thodos (232) reported that both Fl Alumina and  fly ash were
capable of removing up to 99 percent of influent phosphate
levels.  Ames and Dean (13) demonstrated that an alumina column
could treat up to 400 column volumes before reaching the 10
percent phosphorus breakthrough level.

     Since color is contributed largely by organic compounds  in
water, high color removal levels with adsorption should be pos-
sible.  Zanitsch and Morand (712 ) demonstrated 90 percent
color removal.  They also noted an 86 percent suspended solids
removal,  presumably by filtration.

ELEMENTAL CONTAMINANTS

     Not a great deal of literature is available on the removal
of elemental contaminants by carbon adsorption.  Such systems
are not specifically designed to remove ionic elemental con-
taminants, but some elementals are incidentally removed.  When
the metallic contaminants are in an organometallic complex,
carbon adsorption columns can remove specific species.  Litera-
ture from several sources (315, 372 ) reveals that high removals
(95 percent) of cadmium and hexavalent chromium by carbon ad-
sorption are possible.  Huang and Wu (303) found that the effi-
ciency of chromium removal increases with  decreasing chromium
concentration.  While the mechanism of removal  is not well
understood, Roersma et al. (549) were able to describe the
reduction of Cr+6 to Cr+3.  The Cr"1"6 is adsorbed within the
pores of the activated carbon which, in turn, is slowly oxi-
dized to COg, reducing the chromium ion.

     Activated carbon treatment of a secondary-treated munici-
pal wastewater was found to reduce selenium from 9.32 to 5.85
ppb in a study cited by Patterson ( 506).  This represents a 37
percent removal efficiency.  Patterson cited a second study in
which the selenium removal efficiencies of several advanced
wastewater treatment processes were determined in t'he treatment
of secondary effluent containing 2.3 ppb selenium.  While sand
filtration alone reduced the effluent concentration by 9.5 per-
cent, sand filtration followed by activated carbon treatment

                               59

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provided a cumulative removal of 43.2 percent of the selenium
from the secondary effluent.

     Logsden and Symons (394) researched the removal of mercury
by carbon adsorption and found that powdered carbon, in a  jar
test, would adsorb both inorganic and methyl forms  in excess  of
70 percent.

B.IOCIDAL CONTAMINANTS

     Carbon adsorption is widely applied to remove  organic or
metaV-organic biocides.  The removal of insecticides and pesti-
cides has been reviewed by Hager and Flentje (278).  Dieldrin,
lindane, parathion, and 2, 4, 5-T ester were reduced below the
detectable limit of 0.01 ppb with influent concentrations  of
3.6 to 11.4 ppb.  Influent concentrations of 3, 5 dinitro-o-
cresol of 30 to 180 ppb were reduced to less than 1 ppb by
carbon adsorption.  It was concluded that granular  carbon  beds
will  provide a margin of safety for treatment of water contain-
ing varying insecticide or pesticide residues.

     Activated carbon removals of several pesticides and PCB's
are well illustrated by results of laboratory studies cited by
the California State Water Resources Control Board  (615 ), as
shown in Table  34.  A variety of pesticides were experimentally
added to distilled water and passed through carbon  filters to
test  removal  efficiencies.  Schwarz  (570) investigated the  ad-
sorption of isoprophyl N-(3-chlorophenyl) carbamate (CIPC) onto
activated carbon, concluding that powdered activated carbon
readily adsorbs CIPC from aqueous solution.  The adsorption of
CIPC  on activated carbon was independent of the pH  in the  range
of 5  to 9.

     Grover and Smith (272) studied adsorption onto activated
carbon of the  acid and dimethylamine forms of 2, 4-D, and
dicarbamate.   A strong adsorption effect was noted  on both the
acidic and salt forms of the compounds.  This effect was expec-
ted to increase at low pH values.

     On the basis of the literature which has been  reviewed,  it
can be concluded that activated carbon adsorption is effective
in the removal  of some biocidal contaminants; however, further
investigation  of this process will  be useful.

SYNTHETIC/ORGANIC CONTAMINANTS

     As was mentioned earlier, activated carbon is  most erfec-
tive  at removing organic contaminants from aqueous  solutions.
It is particularly effective at removing organics of low water
solubility, as are many synthetic organic compounds.  In general,
carbon adsorption following secondary treatment is  capable of


                               60

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TABLE  34.   REMOVAL OF SPECIFIC TOXIC MATERIALS
          BY CARBON ADSORPTION (615)
Carbon
Dosage (mg/£)
Control
1.0
2.0
2.5
5.0
10.0
12.5
25.0
50.0
AldHn
48
—
26
«
15
12
—
6.3
4.4
Endri n
62
--
15
—
3.4
1.5
—
0.56
0.22
Residual (ppb)
Oleldrin DDT ODD DDE Toxaphene Arochlor 1242
19 41 56
41
6.3 — 6.9
21
2.4 3.7 3.7
1.1 ~ 2.2
<1
0.45
0.35
38
34
—
29
12
—
3.3
1.1
0.9
155 45
147
80 7.3
—
31 1.6
2.7 1.1
_.
-„
—
Arochlor 1254
49
—
37
—
17
4.2
—
1.6
1.2

-------
 producing  an  effluent  with  from  1  to  7  mg/t  of  organic  carbon
 (233).

      Bishop et  al.  ( 68 )  found  that carbon adsorption was  least
 effective  in  removing  highly  polar, highly soluble organic
 species.   DeWalle  and  Chian  (167)  found  that  removal was a
 function,  at  least  in  part, of  the molecular  weight of  the
 synthetic  organic  contaminant:   low (<100) and  high (>50,000)
 molecular  weight compounds are  poorly adsorbed.  The major
 fraction removed by adsorption  falls  into a  100  to 10,000 mole-
 cular weight  range.

      Studies  of the adsorption of  93  petrochemicals by  Giusti
 et  al .  (249)  confirmed  the results of Bishop et  al.  (68)  and DeWalle
 and  Chian  (167); adsorption is largely a function of molecular
 weight, polarity, solubility,  and branching.   Ability  to function
 substantially affected solubility and  polarity.   The relative
 amenabilities to carbon adsorption  of  straight chain molecules
 of  fewer than four carbon atoms  were  as  follows:  >aldehydes
 >esters >ketones >alcohols >glycols.   For larger molecules,  the
 alcohols moved ahead of the esters.

     Much  of  the research done on the adsorption of synthetic
 organic compounds from wastewater has been concerned with
 determining mechanisms of adsorption and optimum removal con-
 ditions.   The only general removal  efficiency studies  available
 report  removals in terms of total organic carbon with  little or
 no  effort  made to differentiate  the organic compounds  involved.
 Based on these results, adsorption can reduce the levels of
 synthetic  organic compounds in a typical domestic wastewater by
 75  to 85 percent.  If a particular type or types of organic
 compounds  predominate in a wastewater, these  removals  must be
 adjusted to reflect the effect of compound character on the
 adsorption process.

 BIOLOGICAL CONTAMINANTS

     With  the exception of enteroviruses, no  information was
 found on the adsorption of biological  contaminants, although
 incidental  removal  of other organisms  would be expected by
 filtering action.   Adsorption brings about simple removal of
 viruses  from wastewater rather than inactivation or destruction
 (140, 242).  Consequently, viable viruses could be reintroduced
 to wastewater should desorption of viruses adsorbed to activa-
 ted carbon  occur.

     Columns of granular activated  carbon removed between 18
and 40 percent of Type I polio virus  from secondary effluent
 in studies  by Sproul et al. (  609).  This research and research
by Gerba et al . (241)  using Type I  polio virus indicate that
adsorption  is  inversely related to  the concentration of organic
matter in the wastewater. * The organics  and the virus  compete

                              62

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for adsorption sites; consequently,  desorption  of  virus  can
occur as adsorption of organic matter continues, or  if  the
concentration of organics is increased.   Several authors  have
thus concluded that the process is not dependable  for  producing
virus-free effluents (133,  242,  609  ).                         •

     The level of removal actually attained is  closely  related
to the type of treatment that precedes adsorption.   For  example,
reducing the concentration  of soluble organics  in  wastewater
by lime coagulation increased polio-virus removal  in studies  by
Gerba et al. (240,  241).  In addition, the degree  of virus  ad-
sorption from lime-treated  wastewater exceeded  that  from fil-
tered wastewater.  These investigations  also showed  that polio-
virus removal from wastewater effluents  is greatly improved  by
maintaining a pH value in the range  of 3.5 to 4.5.   It  was
found that virus adsorbed at low pH  could become desorbed by  a
rise in pH.
                              63

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            TERTIARY TREATMENT:  CHEMICAL TREATMENT
 INTRODUCTION

     The  purpose of chemical treatment is to coagulate suspen-
 ded  solids  and cause the precipitation of phosphate and various
 trace metals.  Chemical coagulation of secondary effluents may
 be accomplished by the addition of lime, alum, polymers, or
 iron salts, and involves three operations:  (1) injection and
 rapid mixing of the coagulants to neutralize the predominantly
 negative  charges on suspended matter; (2) gentle stirring to
 promote agglomeration of the coagulated particles into large,
 settleable  floe; and (3) sedimentation to provide gravity sep-
 aration  of the flocculated material from the wastewater.  The
 settled material is disposed to a sludge-handling system.  As
 indicated by Table  35, a great deal of information is avail-
 able concerning the removal  of various public health impairing
 contaminants by chemical treatment processes.

 WATER QUALITY PARAMETERS

     Culp and Shuckrow (151) investigated chemical  treatment of
 raw wastewater with lime and found that removals of 95 to 98
 percent phosphorus and 99 percent suspended solids  can be
 achieved with chemical  clarification followed by carbon adsorp-
 tion.  The treatment of municipal  wastewater with alum precipi-
 tation as studied by Shuckrow et al.     ( 582) resulted in
removal  efficiencies of 85  percent for COD and 83 percent for
 total organic carbon.

     The removal  of BOD, suspended solids, and phosphorus as
reviewed by Lager and Smith (368)  is summarized in  Table 36
Removals from secondary effluents  of the magnitudes listed
obviously provide a high quality effluent.
                              64

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TABLE 35.   LITERATURE  REVIEWED PERTAINING TO CHEMICAL  TREATMENT
Contaminant                   Reference Number
Water Quality Parameters

  Ammonia               21, 65, 150, 155, 204, 301,  310,  438,
                        440, 613, 700

  BOD                   64, 69, 150, 151, 155, 178,  261,  310,
                        368, 387, 389, 397, 398, 432,  438,
                        479, 489, 490, 569, 622, 646,  649,
                        651 , 676, 700

  Chlorides             438

  COD                   64, 65, 69, 134, 150, 151, 155, 174,
                        261 , 438, 582

  Cyanides              58, 453, 477

  Fluorides             215, 613

  Nitrates              64, 65, 69, 134, 150, 151, 155, 174,
                        261, 438

  Nitrites              155, 204, 440, 517, 613, 700

  Phosphates            6,  10,  32,  59, 64, 65, 69, 150, 151,
                        155, 156, 160, 172, 173, 195, 215,
                        218, 248, 269, 301, 310, 331, 354,
                        367, 368, 376, 387, 389, 398, 426,
                        431, 438, 440, 489, 490, 495, 497,
                        567, 569, 590, 607, 613, 622, 625,
                        649, 651, 675, 693, 700, 707, 710

  Suspended solids      18,  59, 64, 65,  134,  151, 175, 261,
                        301, 349, 368, 389, 397, 443, 479,
                        489, 490, 569, 582, 623, 649, 651,
                        686, 700

  Total dissolved
  solids                 150, 569, 613

  Total organic
  carbon                 64,  65, 69, 155, 582, 676

  Other  (general)        203, 205, 206, 280,  318
                               65

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TABLE 35  (continued)
Contaminant	Reference Number	
Elemental  Contaminants
  Aluminum               178, 398, 495, 644
  Antimony               18
  Arsenic                18, 419, 453, 506, 615, 644
  Barium                  18, 419, 506, 615, 644
  Boron                   644
  Cadmium                18, 19, 58, 391, 419, 453, 525, 615,
                         644, 696, 697, 698
  Chromium               18, 19, 106, 391, 419, 615, 644, 696,
                         697, 698
  Cobalt                  644
  Copper                  18, 19, 58, 106, 419, 453, 615, 644,
                         696, 697, 698
  Iron                    18, 178, 376, 615, 644, 696, 698
  Lead                    419, 453, 615, 644, 696, 698
  Manganese               18, 178, 215, 419, 615, 644, 696,
                         697, 698
  Mercury                 18, 379, 394, 419, 453, 513, 615,
                         631, 644, 696, 697, 698
  Molybdenum              18, 615
  Nickel                  18, 419, 453, 615, 644, 696, 697
  Selenium                391, 615, 644
  Uranium                 18, 615
  Zinc                    18, 58, 419, 453,  615, 644, 696, 697,
                         698
  Other (general)         18, 372, 389, 615, 698
                               66

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TABLE 35  (continued)
Contaminant                	Reference Number	_^
Synthetic/Organic           ,.  fiQ,
 Contaminants              a, o»i
Biological Contaminants
  Adeno virus            705
  Bacteria               38, 176, 179, 338, 389, 407, 649
  Coliforms              55, 155, 243, 389, 443, 649
  Coxsackie virus
  (A&B)                  51, 705
  CHO virus              705
  Escherichia coli       433, 561, 643
  Fecal streptococci     389
  Hepatitis              241, 705
  Parasitic worms        407
  Polio virus            56, 86, 118, 262, 601, 609, 643,
                         700, 705
  Protozoa               407
  Salmonella             338
  Virus                  38, 48, 50, 51, 86, 116, 117, 132,
                         133, 138, 154, 155, 176, 198, 199,
                         242, 416, 487, 504, 510, 575, 602,
                         608, 609, 700, 701
                               67

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       TABLE  36.  REMOVALS ACHIEVED BY CHEMICAL
                     CLARIFICATION (368)
Chemical
Lime pH 11.5
Ferric Chloride
170 mg/£ dose
BOD
Removal
(Percent)
80
80
Suspended Solids
Removal
(Percent)
90
95
 Ferric Chloride              75
  80-100 mg/l  dose
      Phosphate  removal  by  chemical  precipitation  (lime)  has
 received  considerable  attention  in  the  literature  in  recent
 years.  The  research on phosphate  removal  in  general  indicates
 that  lime clarification usually  provides  removal  efficiencies
 greater than  90  percent.   This  is  supported by  the work  of
 Davis  (160),  Sturm  and  Hatch  (625  ),  Johnson  (331), and  '
 Bernhardt et  al.  (59 ).

 ELEMENTAL CONTAMINANTS

     The  precipitation  of  metal  hydroxides from solution 1s
 governed  by  the  pH  and  the concentration  of the metal ion in
 solution.  Since  many of the  trace metals  form  insoluble hydro-
 xides  near pH 11, lime  coagulation results in a reduction of
 these metal concentrations.   Table 37           (615  ) summari-
 zes the effects af  lime coagulation on a  number of heavy me-
 tals.  Some of  the   data were  collected on industrial  metal
 wastes characterized by metal ion concentrations a great deal
 higher than would occur in any municipal  plant  influent.  The
 data are  included here as examples of possible metal  reduc-
 tions, since such figures from chemical coagulation of munici-
 pal wastewaters are scarce.

     As can be seen from these figures, arsenic, molybdenum,
and selenium had relatively poor removal  rates,and the poten-
tial removal  of mercury was estimated to  be low.  Only 11 per-
cent of hexavalent chromium was removed,  although the trivalent
form was reduced more than 99.9 percent.  Most other metals
tested were very effectively reduced at high pH.  Lower  remo-
vals of these same metals (usually less than 50 percent) can be
achieved with alum coagulation at near neutral pH values
(615 ), a  fact that illustrates the dependence of precipitation
on pH .
                              68

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TABLE 37 .   REMOVAL OF ELEMENTAL CONTAMINANTS
           BY LIME COAGULATION (615 )
Metal
Antimony3
Arsenic3
Barium3
Bi smuth3
Cadmium
Chromium (+6)
Chromium (+3)
Copper
Gold3
I ron
Lead3
Manganese
Mercury3
Molybdenum
Concentration
Before Treatment
mg/£
--
23
--
--
Trace
0.0137
0.56
7,400
15
15,700
7
7
302
15
--
13
17
2.0
15
2.3
2.0
21.0

Trace
11
Concentration
After Treatment
mg/£
--
23
1.3 (sol)b
.0002 (sol)
0.00075
0.050
2.7
0.4
0.79
1
.05
Trace
0.6
<.001 (sol)
2.4
0.1
1.2C
<.001 (sol)b
0.5
Y.ic
0.05
Oxide Soluble
9
Percent
Removal
90
0


Abt. 50
94.5
11
99.9 +
97
99.9 +
86
93
99+
97
90+
82
99 +
40
90+
97
96
45
95
<10
Abt. 10
18
                        69

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TABLE  37  (continued)
Metal
Ni ckel




Seleni um
Si 1 ver
Tel uri uma »"
Ti tanium3 >d
Urani urn6
Zinc

Concentration
Before Treatment
160
5
5
100
16
0.0123
0.0546
--
--
--
17
- -
Concentration
After Treatment
mq/i
0.08
0.5
0.5
1.5
1.4
0.0103
0.0164
(< 0.001?)
(<0 . 001 ? )
7
0.3
.007 (sol)
% Removal
99.9+
90
90
99
91
16.2
97
( 90+)
( 90+)
7
98
90+
  The potential removal of these metals  was  estimated from
    solubility data.
  Barium and lead reductions and solubilities are based
c   upon the carbonate.
  These data were from experiments using iron and manganese
 .   in the organic form.
  Titanium and telurium solubility and stability data made
    the potential reduction estimate unsure.
  Uranium forms complexes with carbonate ion.  Quantitative
    data were unavailable  to allow determination of  this effect
                             70

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     Pilot plant studies of municipal  wastewater  containing  5
mg/£ arsenic cited by Patterson (506 ) suggest that  chemical
treatment can provide efficient removal  of this  element.
Ferric sulfate at 45 mg/£ Fe and pH 6.0  removed  90  percent of
the arsenic; lime at 600 mg/£ and pH 11.5 removed 73 percent.
In similar studies cited by Patterson, barium removals  of 97
percent were obtained when municipal wastewater  dosed with 5
mg/£ barium was treated with 45 mg/l Fe  at pH 6.0.   Lime at
600 mg/£ and pH 11.5 resulted in 80 percent removal. The re-
moval of cadmium from waters by sorption onto hydrous oxides  of
solid metals such as manganese and iron  was investigated by
Posselt and Weber (  525 ).  They concluded that sorptive uptake
of cadmium on such materials would constitute a  method  easily
adaptable to present treatment technology.

BIOLOGICAL CONTAMINANTS

     Chemical treatment can be used to reduce or remove many
biological pathogens present in municipal wastewater.  Lindstedt
and Bennett (389) evaluated the effectiveness of lime clarifi-
cation in reducing bacterial concentrations, finding that
treatment effectiveness increases with increasing chemical
dosage and pH.  At a lime dosage of 400  mg/£ , fecal coliform,
fecal streptococcus, and total coliform  concentrations  could be
reduced by two orders of magnitude.  It  was also found  that
about 90 percent removal of bacteria can be achieved through
alum clarification over a broad range of alum dosage.

     Jar tests employing the f2 bacteriophage virus, lake
water, and a variety of chemical coagulants and polyelectrolyte
coagulant aids were conducted by York and Drewry (705 ).  As
shown in Table  38,  aluminum sulfate (alum), ferric chloride,
ferric sulfate, ferrous sulfate, and polyelectrolyte B  were
found to give maximum virus removals greater than 90 percent at
optimum dosage.
                              71

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      TABLE  38  .  COMPARISON OF THE EFFECTIVENESS OF
                THE COAGULANTS TESTED (705 )
Coagulants-
Coagulant Aids
A12(S04)3
FeCl3
Fe2(S04)3 x H20
FeS04 and Ca(OH)2
Al2(S04h and
Na2OA I2U3
Polyelectrolyte A
Al2(S04)3 and
polyelectrolyte B
Polyelectrolyte B
A12(S04)3 and
polyelectrolyte B
Al2(S04)3 and
polyelectrolyte C
A12(S04)3 and
polyelectrolyte E
A12(S04)3 and
polyelectrolyte F
Al2(S04)3 and
polyelectrolyte D
Dose
25
50
50
36
30
23
2.0
18
1.0
2.0
18
0.7
18
0.4
18
0.1
18
0.1
18
1.0
Maximum
Virus
Removal
percent
99.9
99.4
92.0
93.5
98.6

76
99.2

99.6
99.8

99.3

99.3
99.6

99.4
Berg et al.  ( 56 )  experimentally mixed polio virus I  and secon-
dary effluent in containers, added lime, and stirred  the solu-
tion for 15  min to allow formation of floe particles.   Settling
                to 75 min.  The removals obtained with varying
                are shown in Table  39 .   Large coagulant doses
were capable of effecting virus removals of up to 99.9 percent.
After further investigation, the authors concluded that signi-
ficant destruction of viruses can be attributed to the high
pH occurring with  high lime concentrations (in the range of 400
to 500 mg/£).
followed for 60
dosages of lime
                             72

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   TABLE  39 .   REMOVAL  OF  POLIO  VIRUS  1  FROM  SECONDARY
        EFFLUENT BY  FLOCCULATION WITH  Ca(OH)2  (56  )
Ca(OH)2
Concen-
tration
mg/l
200
300
400
500
500
Initial Virus
Concen-
tration
pfu/£
33,333
51,480
55,000
33,333
33,333

pH of
Treated
Effluent
9.30
10.21
11.30
11.03
11.01
Surviving Virus
Concen-
tration
pfuAe
2,200
15,912
1,940
505
47

Vi rus
Removal
percent
92.3
69.1
96.5
98.5
99.86
     Chaudhuri  and Engelbrecht (116)  used  water devoid  of
extraneous organic matter in their laboratory  investigation  of
virus removal  with alum.   Using the experimentally  determined
optimum pH and  dosage, 98.0 percent removal  of bacteriophage
T4 and 99.9 percent removal of bacteriophage MS2 were  obtain-
able.  However, the addition of organic  matter in the  form of
albumin or treated wastewater lowered these  efficiencies.   For
example, only  95.7 percent removal of bacteriophage T4  was ob-
tained after the addition of 200 ml/I of settled wastewater.
Further experiments demonstrated no inactivation of the virus
particles that  were removed in the settled floe.  However,
Brunner and Sproul (86 )  demonstrated 60 percent permanent  inac-
tivation in the case of polio virus I removed  from  solution
with aluminum  phosphate precipitates.  Their studies of polio
virus I and bacteriophage T2 removal  showed  that under optimum
conditions, removals can  reach 98 and 94 percent, respectively,
with aluminum  and calcium precipitation.  Actual removals  are
related to pH  and chemical dosage.

     Chemical  treatment (high pH) holds  considerable promise
as a means of  effectively inactivating or  destroying pathogenic
organisms contained in wastewater.  By itself, chemical treat-
ment cannot be  relied upon to produce a  pathogen-free  effluent;
used in conjunction with  disinfection, however, it  can help
ensure that such an effluent is achieved.
                              73

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                TERTIARY  TREATMENT:  ION EXCHANGE
 INTRODUCTION
      The process  of selective ion exchange  has  long  been  uti-
 lized in the treatment of industrial  process  waters  and  in  domes-
 tic  water supply  softening.   Ion  exchange resins  (539) are
 classified by  the charge of  the exchangeable  ion.  Thus,  resins
 may  be  either  catonic or anionic.   General  purpose resins will
 selectively exchange both cations  and  anions.   The operational
 features of the  ion exchange  process are well developed and
 reliable.   Such  systems  offer a reliable method of removing
 inorganic  contaminants  from  the wastewater  stream.

      As  can be seen by  an examination  of Table  40 ,  very  little
 information is currently available  on  removals  of  contaminants
 from  municipal wastewater by  use  of ion exchange techniques.
 The  process  has not been economically  feasible  for treatment of
 municipal  wastewater.   Several research programs focusing on
 the  application of  ion  exchange to municipal wastewater treat-
 ment  are presently  under way.  The most promising  future appli-
 cation appears to be  for ammonia or nitrate removals.

 WATER QUALITY PARAMETERS

      Eliassen and Tchobanoglous (194,  195)  conducted a review
 of the literature.  They  found that removals of phosphorus and
 nitrogen by tertiary wastewater treatment incorporating ion
 exchange can reach  90 percent.  The actual  removal efficiency
was seen to depend  upon  the type of preceding treatment.   Evans
 (209) investigated  the removal of nitrate by ion exchange, con-
cluding that the strong  acid/weak base ion  exchange process  is
well  suited for this purpose.  With the exception of these few
studies of phosphorus and nitrate, most research performed to
date  has focused on ammonium removal,  since  specific  exchange
resins are not available for either the phosphorus or nitrate
ions.  However, some zeolite exchange resins do  have  unusual
selectivity for the ammonium ion.   This fact has encouraged
research activity.

     On the basis  of both pilot and laboratory scale  investiga-
tions, it appears  that effluent ammonia concentrations  of  less
than  1 mg/£ can be expected with  ion exchange  (362, 438)    In
                              74

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  TABLE 40.   LITERATURE REVIEWED PERTAINING TO ION EXCHANGE
Contaminant
           Reference Number
Water Quality Parameters
  Ammonia

  BOD
  COD
  Chlorides
  Ni trates
  Nitri tes
  Phosphates

  Suspended solids
  Total dissolved
  sol ids
  Total organic
  carbon
  Other
Elemental  Contaminants
  Arsenic
  Boron
  Cadmium
  Chromium
  Cobalt
  Iron
  Lead
  Manganese
  Mercury
3, 65, 90, 103, 150, 194, 233, 362,
438, 445, 517, 539, 694
64, 65, 103, 150, 255, 438
64, 65, 103, 150, 196, 438, 707
196, 438
3, 65, 90, 194, 195, 209, 539, 694
90, 194, 694
64, 65, 103, 150, 194, 195, 196, 197,
209, 238, 438
3, 64, 65, 103

103, 121, 150, 233, 707

64, 65
280, 318

275, 506, 576
538
370, 391 , 506
370, 391 , 506, 542, 549
370
370
370
370
370, 391 , .452, 506
        75

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TABLE 40  (continued)
Contaminant                           Reference Number
tlemental Contaminants
  Nickel                  370
  Selenium                391
  Other                   372,  506
Synthetic/Organic
 Contaminants               271 ,  541
                                76

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a pilot plant study,  Mercer  et al.  (445) used zeolite columns to
test secondary effluent  containing  10-19 mg/l ammonia.  Greater
than 99 percent removal  of ammonia was achieved.  Similarly, 99.7
percent of the ammonia in activated carbon effluent  was  removed
by a zeolite in laboratory scale experiments  by McKendrick   et
al. (438).

     The Environmental Protection Agency (517) reviewed pilot
plant studies involving  the use  of clinoptilolite -  a naturally
occurring zeolite - for  wastewater treatment.   Ammonia removals
ranged from 93 to 97 percent.

     It should be noted  that the ion exchange process using  a
zeolite such as cl inoptilol ite does not result in the produc-
tion of a sludge containing the  removed ammonia.   Rather, the
spent zeolite is regenerated with a lime slurry,  which is sub-
sequently air stripped,  discharging ammonia to the atmosphere.

ELEMENTAL CONTAMINANTS

     Ion exchange techniques have been principally applied for
the removal of elemental contaminants from industrial waste
streams (506 ).  Few studies have dealt with the application of
ion exchange techniques  to municipal wastewaters for elemental
contaminant removal.  Lindstedt et al . (391) investigated trace
metal removal and concluded that a cation-anion exchange se-
quence was effective in reducing the concentrations of cadmium,
chromium, and selenium in secondary effluent.  Removal effi-
ciencies are summarized  in Table  41.


   TABLE  41  .  TRACE METAL REMOVALS BY ION EXCHANGE (391)	

                   Percent Removal        After Given Process
                       Cation               Cation-Anion
Trace Metal           Exchange                 Exchange
Cadmium
Chromium
Selenium
99
5
1
99.9
96
99.7
BIOCIDAL CONTAMINANTS

     Biocidal contaminant removal through ion exchange has also
received little attention in the literature.  In the only study
located, Grover (271) stated that trifluralin, triallate,
diallate, and  nonionic  herbicides were readily adsorbed on
both cationic and anionic exchange resins, with somewhat more
adsorption occurring on the cationic than on the anionic form.

                               77

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                  NITROGEN REMOVAL PROCESSES
 INTRODUCTION
     Interim primary drinking water standards established by the
EPA set a nitrate limit of 10 mg/8, in the nitrogen form.  Nitro-
gen concentrations in raw municipal wastewaters generally exceed
this value, ranging from 15 to 50 mg/si.   Unless facilities are
specifically designed to remove nitrogen, much of it will remain
essentially unaffected, passing through the varying stages of
treatment to ultimately enter the environment.  Moreover, reuse
of wastewater treatment plant effluents for direct groundwater
recharge, indirect groundwater recharge through land application,
or indirect reuse as a potable water supply is on the increase.
Such reuse policies make effective nitrogen removal an important
aspect of any wastewater treatment scheme.

     In raw municipal wastewater, nitrogen is primarily found in
the form of both soluble and particulate organic nitrogen and as
ammonium ions.   Conventional primary and secondary treatment
transforms some of this organic nitrogen into ammonium ions.
Part of the ammonium ion is oxidized to nitrate, and about 15 to
30 percent of the total nitrogen is removed.

     Tertiary treatment processes designed to remove wastewater
constituents other than nitrogen often remove some nitrogen
compounds as well.   However, removal  is  often restricted to
particulate forms,  and overall  efficiency is  generally low.  Two
tertiary processes  particularly designed to remove nitrogen have
been developed:   nitrification-denitrification and ammonia
stripping.   Tertiary nitrification-denitrification usually
involves two stages.   Nitrification occurs in an initial stage,
during which ammonium ions  are oxidized  to nitrite and nitrate
ions by nitrifying  bacteria.   These nitrite and nitrate ions are
in turn reduced to  nitrcger. ca: whicn : Imply  escapes fro-n ti->e
system.

     Ammonia stripping is effective o";y in removing ammonia
nitrogen from municipal wastewater and has no effect on organic
nitrogen, nitrite,  or nitrate.   Several  ammonia strapping plants
are in operation in the U.S.  (Lake Tahoe, California,  Orange
County, California),  but the process  has been found to be
expensive.   A number of technical problems remain to be solved
as well (438).


                               78

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     Nitrification and denitrification are biological  reactions
which occur naturally during several  conventional  treatment
processes such as activated sludge treatments,  aerobic lagooning,
and anaerobic digestion.   The activated sludge  process,  in
particular, can be closely controlled to promote nitrogen removal.
Such treatment processes  are not principally designed  to remove
nitrogen, and both nitrification and  denitrification occur only
as secondary reactions.  For ease of  reference, however, all
literature reviewed on the general topic of nitrogen removal  has
been tabulated on Table  42, including tertiary processes
specifically designed for this purpose.

WATER QUALITY PARAMETERS

     There is general agreement that  a system incorporating
secondary biological treatment and tertiary nitrification-
denitrification should achieve 80 to  95 percent total  nitrogen
removal at design flows (280, 483).   The nitrification process
alone removes only 5 to 10 percent of the total nitrogen entering
the process, while oxidizing up to 98 percent of the ammonia
nitrogen present to nitrate (236).

     Average nitrogen data from systems incorporating nitrifica-
tion-denitrification processes recorded by an EPA Technology
Transfer Publication (236) is presented in Table 43 .   Based
on this report, the predicted effluent quality from a nitrogen-
denitrification system will be 1.0 mg/a organic nitrogen, 0.5
mg/x, ammonia nitrogen, 0.5 mg/a nitrate nitrogen, and 2.0 mg/si
total nitrogen.

     Nitrification is in itself an oxygen-demanding process and
therefore reduces the total oxygen demand (TOD) in  the waste-
water effluent.  Conventional biological or physico-chemical
treatment obtaining up to 90 percent BOD reduction  will only
partially reduce the TOD of treated wastewater.  For  instance,
such treatment will only reduce an influent TOD of  490 mg/£ to
an effluent TOD of over 100 mg/a.  Nitrification will  reduce the
TOD of this effluent to less than 40 mg/a (236).

     Since the denitrification step involves the oxidation of
carbonaceous material, a reduction in  biochemical oxygen demand
and total organic carbon can also be expected, in addition to
the effective reduction of TOD.

     Nitrogen removal by ammonia  stripping was studied  by
O'Farrell et al. (492), who reported a 90 percent removal of
ammonia from a non-nitrified, lime-clarified secondary  effluent
at pH 11.5.  During a warm weather study performed  at Lake
Tahoe, stripping produced a 95 percent removal of ammonia
nitrogen at pH 11.5 and using 400 cu ft of air per  gallon of
wastewater (280).  Any arbitrary  percentage removal can  be
                               79

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achieved with this type of system within available engineering
capabilities, although higher removals mean higher costs.
                              80

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          TABLE 42.   LITERATURE REVIEWED  PERTAINING  TO
                        NITROGEN REMOVAL
Contaminant	Reference  Number	

Water Quality Parameters

  Ammonia                   3,  4,  6,  40,  66,  127,  194,  204,  236,
                            280,  328, 428,  438,  475,  483,  492,
                            517,  527, 539,  594,  620,  630,  684,
                            694,  706

  BOD                       40, 236,  330

  Chlorides                 403

  Nitrates                  3,  4,  40, 194,  195,  204,  236,  256,
                            257,  327, 328,  330,  428,  475,  483,
                            517,  527, 539,  594,  629,  630,  694

  Phosphates                194

  Suspended
  solids                    40, 330,  629
                               81

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          TABLE   43.   EFFLUENT  NITROGEN  CONCENTRATIONS IN
     TREATMENT SYSTEMS INCORPORATING NITRIFICATION - DENITRIFICATION
                                 (236)

	Average Effluent Nitrogen, mg/l

 Type and  Process Sequence        Organic-N   NHj-N    NO^-N    NO^-N  T°Sal

 Lime treatment of  raw sewage,     1.1        0.3      0.5      0.0    1.9
    nitrification,
    denitrification

 Primary treatment,                0.8        0.0      0.7      0.0    1.5
    high rate activated
    sludge, nitrification,
    denitrification,
    filtration

 Primary treatment,                0.8        0.9      0.6      0.0    2.3
    roughing filters,
    nitrification,
    denitrification,
    filtration
                                    82

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                           SECTION  6

                  DISINFECTION:   CHLORINATION
INTRODUCTION
     Until  recently, chlorination was  considered  virtually  an
unmixed blessing as a cheap, effective method  to  destroy  bac-
teria and viruses.  It is now recognized,  however,  that chlori-
nation of wastewater may create chlorinated  compounds  harmful
to the environment and to human health.  The extent of this
potential hazard has not yet been determined;  new and  existing
wastewater treatment plants continue to utilize chlorine  for
disinfection.  The primary purpose of  municipal wastewater
chlorination is the destruction of pathogenic  microorganisms.
This is reflected in the literature reviewed,  shown in Table 44.

WATER QUALITY PARAMETERS

     Zaloum and Murphy (711) concluded that  chlorination  of
treated wastewater effluents does not  reduce BOD, COD, and  total
organic carbon.  Susag (1346), however, found  BOD reductions  by
chlorination of up to 2 mg/£ per mg/t  of chlorine added.   These
values are somewhat misleading, in that BOD  reduction  was due
both to oxidation of the organic material  and  to the formation
of chlorinated organics resistant to bacterial action.

     When chlorine is added to a wastewater  containing ammonia
nitrogen, ammonia reacts with the hypochlorous acid formed  to
produce chloramines.  Further addition of chlorine converts the
chloramines to nitrogen gas.  The reaction is influenced  by pH,
temperature, contact time, and initial chlorine-to-ammonia
ratio.  If sufficient chlorine is added, 95  to 99 percent of
the ammonia will be converted to nitrogen gas with no  signifi-
cant formation of nitrous  oxide.  The  quantity of chlorine
required was found to be 10 parts by weight  of chlorine to  1
part of ammonia nitrogen when treating raw sewage.  This  ratio
decreased to 9:1 for secondary effluents, and 8:1 for lime-
clarified and filtered secondary effluent (627 ).

ELEMENTAL CONTAMINANTS

     Little information  is available on the minimal removal by
chlorination of elemental  contaminants.  Andelman  (16) studied


                               83

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    TABLE 44.  LITERATURE REVIEWED PERTAINING TO CHLORINATION
Contaminant	Reference Number	
Water Quality Parameters
  Ammonia                 21, 36, 62, 65, 71, 360, 361, 517,
                          531, 597, 713
  BOD                     65, 171, 298, 499, 516, 569, 627, 711
  COD                     65, 516, 520, 627, 711
  Chlorides               342
  Cyanides                28, 499
  Nitrates                65, 342, 517, 614
  Nitrites                360, 361, 517
  Phosphates              65, 342
  Suspended solids        65, 516, 569
  Total  dissolved
  solids                  569
  Total  organic
  carbon                  65, 711
  Others (general)        203, 205, 280, 360, 361, 437, 677
Elemental Contaminants
  Barium                  16
  Boron                    638
  Copper                  16
  Iron                     360, 499
  Manganese               360, 361,  559
  Mercury                 499, 692
  Nickel                   16, 361
                               84

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TABLE 44  (continued)
Contaminant
         Reference  Number
Synthetic/Organic
 Contaminants
Biological Contaminants
  Adeno virus
  Bacteria
  Coliforms

  Coxsacki virus (A&B)
  ECHO virus
  Escherichia coli
  Fecal streptococci
  Hepatitis virus
  Mycobacterium
  Parasitic worms
  Polio virus

  Protozoa
  Salmonella
  Shigella
  Vibrio cholerae
  Virus
  Other (general)
5, 42, 85, 102, 250,  334,  464,  536,
581,  596, 619, 669, 713
49
6, 38, 88, 109, 110, 154, 158, 171,
208, 31 1 ,  332, 407., 604
88, 89,  158, 171, 195, 201, 208, 251,
307, 311,  360, 361, 454, 516, 604,
608, 647,  649, 673, 687, 689
49, 136,  198, 311 ,  439, 564
198, 311 ,  585
75, 195,  201, 223,  311, 564, 656, 661
158, 195,  307, 516
311
223, 311
88, 311 ,  562, 604
88, 118,  198, 311,  401, 404, 564, 585,
601, 659
88, 201,  223, 621
88, 158,  208, 223,  514
88
88
38, 48,  49, 50, 54, 55, 71 , 88, 109,
110, 152,  153, 185, 200, 201, 208,
233, 259,  311, 332, 365, 368, 400,
401 , 447,  463, 487, 514, 575, 584,
585, 604,  637, 664
88, 296
                                85

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the effects  of  chlorination on barium, copper, and nickel.
treatment effected  a  34-percent reduction in barium, a 5"Perce!?n<;
reduction in nickel,  and  had  no effect upon copper.  KokoroDOUic
(360) reported  hypochl orous  acid  reacted with  soluble  iron ^ n i
and manganese (II)  to form precipitates.

SYNTHETIC/ORGANIC CONTAMINANTS
        research was found to address removal or Destruction
 pouns  by              .       . c«». * .«,.„  -•  -...-• --:-        t'tu-
 compounds  in water are diverse,  including  oxidation,  substitu-
 tion,  addition,  and  free  radical  reactions.   Chlorination may
 produce several  different chlorinated  products  from ausing^on
 organic pollutant molecule.   Some of  these compounds  have been
 identified as  toxic  to aquatic  life  by Snoeyink (596 ), Brung*
 ( 85 ) , and others .

      Jolley (334)  evaluated  chlorine-containing organic consti-
 tuents in chlorinated effluents and found that stable chiorm
 containing compounds were present after effluents had been     d
 chlorinated to a 1  to 2  mg/£ chlorine residual.  These compound
 are identified in Table   45.
       TABLE 45.  IDENTIFICATION OF CHLORINE  CONTAINING
          CONSTITUENTS IN CHLORINATED EFFLUENTS  (334)
  2 - Chlorobenzoic acid
  3 - Chlorobenzoic acid
  4 - Chlorobenzoic acid
  8 - Chlorocaffeine
  6 - Chloroguanine
  3 - Chloro-4-hydroxybenzoic
  4 - Chloromandel ic  acid
  4  -  Chloro-3-methylphenol
acid
2 - Chlorophenol
4 - Chlorophenol
4 - Chlorophenylacetic
3 - Chlororesorcinol
5 - Chlorouracil
5 - Chlorouridine
8 - Chloroxanthine
       A similar project was conducted by Glaze and Henderson
  (250)   The chlorinated organics identified  in  this  study  are
  listed in Table 46.

       Shimizu et al. (581) stated  that  halogenated nucleic  ac1d.
  are  incorporated  into  the  nucleic  acid.   Also,  the  Incorporati
  of  5-deoxybromouridine in  DNA and 5-fluorouracil into RNA are
  known  to  cause mutations.  No work has been  completed to deter-
  mine how  nucleic  acids react with chlorine or the resulting
  mutations,

                                  86

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              TABLE 46.  CHLORINATED ORGANICS IN
                   WASTEWATER EFFLUENT  (250)
 Chloroform
 Dichlorobutane  3-chl
 Chlorocyclohexane  (-18)
 0-dichlorobenzene
 P-dichlorobenzene
 Pentachloroacetone
 Trichlorobenzine
 Chiorocumene
 N-methyl-trichloroaniline
 Trichlorophenol
 Chloro-a-methyl  benzyl  alcohol
 Dichloromethoxytoluene
 Trichloromethylstyrene
 Dichloro-a-methyl  benzyl  alcohol
 Dichloro-bis  (ethoxy) benzene
 Dichloro-a-methyl  benzyl  alcohol
 Trichloro-a-methyl benzyl  alcohol
 Trichloro-a-methyl benzyl  alcohol
 Tetrachloroethylstyrene
 Tetrachloromethoxytoluene
 Dichloroani1ine derivative
 Dichloroaniline derivative
Trichlorophthalate derivative
Tetrachlorophthai ate derivative
 Dibromochloromethane
 3-chloro-2-methylbut-l-ene
 Chloroalkyl  acetate
 Tetrachloroacetone
 Chloroethylbenzene
 Hexachloroacetone
 Dichloroethyl  benzene

 Dichlorotoluene
Trichloroethyl benzene
Trichloro-N-methylanisole
Tetrachlorophenol
Trichlorocumeme
Tri chlorodimethoxybenzene
Dichloroacetate derivative
                               87

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 BIOLOGICAL  CONTAMINANTS

     The  effectiveness of  chlorination as a disinfection process
 has  long  been  recognized.  All  researchers are in agreement that
 the  effectiveness  of  disinfection by  chlorine is influenced by
 time and  chlorine  concentration  and also by:  (1) whether the
 chlorine  residual  is  free  or  combined; (2) effectiveness of
 mixing; (3) whether or not particulates are present; (4) pH;
 (5)  temperature; and  (6) the  concentration, condition, and nature
 of the organisms.  Keeping these limitations in mind, an idea
 of the relative resistances of  organisms to disinfection by
 chlorine  can be seen  in Table 47.
 TABLE 47.  EFFECT OF CHLORINATION ON VARIOUS ORGANISMS (311)
Group
Virus
Organism
Infectious Hepatitus
Coxsackie
Coxsackie
Echo
Poliovirus I
Coliphage B
Theiler Phage
Chlorine
Residual
(mg/£)
1
15
5
1.0
1.95
0.53
0.03
0.03
Time
min.
30
30
2.5
3
6.5
14
10
10
Efficiency
Survived
Inactivated
Survived
99.6% Inactivated
Survived
Survived
20% Survival
Inactivated
Bacteria
Nematodes
Others
M. tuberculosis
            E . c o 1 i
Coliforms

Total Count

Diplogaster
Cheilobus

S.  mansoni
Tova and
 miracidia)
S.  japonicum
(ova and
 mirac i d i a)
 1-5
 2
 1
 0.14
 0.03
 1-1.2
 trace

 2.5-3
15-45

 0.2-0.6
                               0.2-0.6
120
 30
 30
  3
 10
 15
 15

120
  1

 30
            30
99% Kill
99% Kill
Destroyed
99.9% Kill
52% Kill
99% Kill
98-99% Kill
Survived
Mobile

Killed
       Ki 11ed
and
Eliassen and Tchobanoglous (195) found that 2 to 6 mg/£ of
chlorine applied for 20 min would effect a 99.99 percent kill
of the total coliforms, fecal coliforms, and fecal streptococci
present in wastewater influent.
                              88

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     The effect of chlorination on entamoebic cysts  was investi-
gated by Stringer and Kruse (621 ).  It was concluded that the
hypochlorous acid (HOC!) form of free available chlorine was
the most rapidly acting cysticide compared with other halogen
species.  Entamoeba histolytica cysts and tapeworm eggs with-
stand the chlorination treatment generally applied to waste
treatment effluent (88).  Rudolfs et al. (562)  reported the
development of active embryos from a majority of  ascaris eggs
in contact with chlorine solutions for  30 min.

     Davis and Keen (158) conducted a research project on the
ability of municipal  wastewater bacteria to survive  chlorination
and reestablish populations after discharge.  Fecal  coliform,
fecal streptococci, and total coliform enumeration was performed
with further differentiation into lactose nonfermenters within
and outside the family Enterobacteriaceae.  It was determined
that the vast majority of the wastewater bacterial species that
reestablished their populations within  21 days following chlori-
nation were lactose nonfermenters not included in the entero-
bacteriaceae.  Many of these bacteria could be pathogenic under
the appropriate conditions and may constitute a threat to public
health in receiving waters designated for contact recreation.

     Virus inactivation is one of the more difficult tasks of
chlorination, but as  in any disinfection process, required kills
can be achieved by lengthening the time or increasing the con-
centration (311).  A  study of the inactivation of viruses in
wastewaters by chlorination was performed by Lothrup and Sproul
(401).  it was ascertained that:

     •  High-level  inactivation of viruses can be obtained in
        treated and untreated domestic  wastewaters.   Present
        chlorination  practices (1 mg/£  of residual), however,
        are inadequate for a high level of virus  inactivation.

     •  A combined chlorine residual of 28 mg/£ was  required
        to produce a  99.99 percent inactivation of the T2
        bacteriophage in settled raw wastewater after a 30-min
        contact time.

     t  A combined chlorine residual of 40 mg/£ was  required to
        provide a 99.99 percent destruction of the Type 1
        polio virus in settled wastewater after a  30-min contact
        time.

     •  Free chlorine residuals of 0.2  to 0.4 mg/l , after 30
        min, produced a complete inactivation of  the polio virus
        and T2 phage  in the secondary effluent.
                              89

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     •  In experimental runs with synthesized storm-water over-
        flow samples, a 100 percent inactivation of the Type 1
        polio virus was obtained by providing a free chlorine
        residual.

     •  The T2 bacteriophage was much less sensitive to combined
        chlorine residuals than are the coliform organisms and
        somewhat more sensitive than the polio virus to combined
        chlorine residuals;

     A similar research project investigating the inactivation
of enteroviruses by chlorination was conducted by Shuval et al.
(585).   The following conclusions were obtained:

     •  The strain of ECHO virus used was sensitive to the com-
        bined chlorine in the sewage, with reductions of 99 per-
        cent in 30 min and 99.93 percent in 6 hr using 3.6 mg/l
        of chlorine.   No virus was recovered in the sample tested
        after 4 hr contact with 7 mg/£ of chlorine dosage or
        after 2.5  hr with 11  mg/l of applied chlorine.  Inacti-
        vation was shown to be a function of time and chlorine
        concentration under the test conditions.

     •  The strain of polio virus Type 1 used was much less sen-
        sitive to  the combined chlorine, showing only 50 and 90
        percent reductions in 6 hr using 4 and 11 mg/l chlorine
        dosage respectively.

     •  Coliform reductions obtained followed known patterns,
        with a standard of less than 100 coliforms/100 ml being
        obtained in 80 percent of the samples after 2 hr of
        contact with a chlorine dose, of about 8 mg/l.

     The minimum concentration of chlorine required for complete
inactivation of the Sabin oral poliovaccine Type I virus strain
was examined by Varma et al.  (659).   Various exposure periods
with pH 5.2 at 20°F were studied.  A concentration of 22 mg/£
for 5 min of exposure time, 19 mg/£ for 15 min, 19 mg/l for
30 min, 17 mg/l for 45 min, and 14 mg/l for 60 min.  Nonetheless,
on the basis of the literature surveyed, it is evident that
chlorination per se does not provide conclusive proof of disin-
fection.

     Boardman and  Sproul (71) described the protection afforded
viruses associated in particulate matter.  Surface adsorption
gave no viral protection.  When viruses are embedded within
particles, the disinfecting molecules must diffuse through the
particle matrix before reaching the virus and initiating any
inactivation.  Chemical diffusion is a slow process; as a con-
sequence, virtually all the embedded viruses are protected from
disinfection.
                               90

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                    DISINFECTION:   OZONATION
INTRODUCTION
     Ozone, an allotropic form of oxygen,  is a powerful  oxidizing
agent for the disinfection of wastewater.   Ozone is used in  over
100 municipalities in Europe for disinfection of drinking water.
Certain chemical  features make ozone treatment a particularly
attractive method of water purification:

     •  It is a powerful  oxidant which reacts rapidly with most
        organic compounds and microorganisms in wastewater.

     •  It does not impart taste and odor  to potable water.

     •  It is produced from oxygen in air  by means of electric
        energy.

On the negative side, the cost of ozonation is not presently
competitive with chlorine disinfection.  Moreover, long-term
residual disinfection capabilities are lacking, and the insta-
bility of ozone generally necessitates its generation on site
( 660 ).

     The principal ozone decomposition products in aqueous
solution are molecular oxygen and the highly reactive free
radicals HOo, OH", and H+.  Very little is known about the sig-
nificance of the free radical intermediates on the germicidal
properties of ozone solutions.  The same free radicals are pro-
duced by irradiation of water, and it has  been reported that
HOs and OH~ radicals contribute significantly to the killing of
bacteria by this process.

     As seen in Table 48, a considerable amount of  information  is
available on the destruction of various pathogens  by ozonation,
however little information was found on the effect of ozone
upon other contaminants.

WATER QUALITY PARAMETERS

     Because of its strong oxidizing character, ozone is very  re-
active toward the organic compounds which make up  the BOD, COD,
and the total organic carbon.  Under ideal conditions the reac-
tions would result in almost complete oxidation and only carbon
dioxide as a reaction product.  In practice, ozonation results

                                91

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     TABLE 48.  LITERATURE REVIEWED  PERTAINING  TO  OZONATION
Contaminant
      Reference  Number
Water Quality Parameters

  Ammonia
  BOD
  COD
  Nitrates
  Nitrites
  Phosphates
  Suspended solids
  Total  organic carbon
  Others (general )
Elemental  Contaminants
Biological Contaminants
  Adeno  virus
  Bacteria
  Clostridium
  botulinium
  Coliforms
  Coxsackie  virus  (A&B)
  ECHO  virus
  iicjierichia  cojj[
  Fecal  streptococci
  Parasitic  worms
6, 244,  332,  353,  545
170,  171,  353,  427,  463,  474
127,  170,  244,  351,  474,  571
244,  332,  474,  545
244,  332,  353,  545
474
244
474,  587
207
227,  228

49, 110
6, 34, 110, 170, 171,  243,  283,
351 ,  353,  556

660
171 ,  244,  351,  402,  673
110
110
34, 49, 343, 344, 351, 660
34, 351
444,  660
                               92

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TABLE 48  (continued)
Contaminant
        Reference Number
Biological Contaminants
  Polio virus
  Salmonella
  Virus
  Other (general)
110, 118, 343, 344, 409
351
49, 50, 51, 110, 152, 170, 259,
400, 402, 508, 509
343
                                93

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in only partial oxidation and produces simpler organic molecules.
Both Ghan and Nebel reported COD removals of less than 40
percent.  Morris found that the apparent BOD of a wastewater can
increase after ozonation as a result of refractory organic
molecules being oxidized to simpler, biodegradable compounds.
If the ozone is applied after other treatment processes (as is
normal), the increase in organic nutrient molecules can lead
to the growth in the distribution system of algae, slime
bacteria, and the possible regrowth of any pathogens not des-
troyed during treatment.

     Ozone is effective at decreasing concentrations of organic
suspended solids and organic nitrogen through oxidation.
Ozonation can assist in suspended solids removal  through froth
flotation mechanisms induced through the process.  Ozone will
also oxidize nitrites to nitrates, but will not react with
ammonia ( 332 ).  There is little evidence to date that ozona-
tion will produce any toxic or carcinogenic oxidation by-products
as will chlorination.

ELEMENTAL CONTAMINANTS

     Furgason and Day (  228   ) studied the feasibility of
ozonation for iron and manganese removal from raw water with
relatively high input concentrations.  The study  demonstrated
that ozone effectively oxidized the iron and manganese to
an insoluble form which could be filtered from the water.

     Complete oxidation of the minerals required  a reaction time
of 30 sec.  Filtration studies indicated a relatively fine
medium was required to remove the oxide precipitate.

BIOLOGICAL CONTAMINANTS

     The use of ozone as a wastewater disinfectant was reviewed
by Venosa (  660 ).  It was concluded that with 0.1 mg/fc of active
chlorine, 4  hr would be required to kill 6 x 10^  E. co1i cells
in water, whereas with 0.1 mg/£ of ozone only 5 sec would be
necessary.  When the temperature was raised from  22°C to 37°C,
the ozone inactivation time decreased from 5 sec  to 0.5 sec.
These investigations revealed that the contact time with ozone
necessary for 99 percent destruction of E. coli was only one-
seventh that observed with the same concentration of hypochlo-
rous acid.  The death rate for spores of Bacillus species was
about 300 times greater with ozone than with chlorine.

     In the  same study, Venosa also described bacteriological
studies performed on secondary effluent from an extended aera-
tion pilot plant in the Metropolitan Sewer District of Louisville,
Kentucky.  Using an average applied ozone dosage  of 15.2 mg/«,
for an average contact time of 22 min, fecal coliform reductions
of greater than 99 percent were achieved, resulting in a mean

                               94

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fecal coliform concentration of 103 cells/100 mi ,  a mean
total coliform concentration of 500 cells/100 mi ,  and a mean
fecal streptococci concentration of 8 cells/100 mi in the
final effluent.  Laboratory results with raw sewage indicated
that ozone could be successfully used to sterilize sewage
containing Bacillus anthracis , influenza virus, and B. s u bt i1i s
morph. g1o b i b i i , and to inactivate toxins of Clostridium
botul i num.  Ozone consumption was 100 to 200 mg/i for 30 min.
Finally, Venosa found ozone to be many times more effective
than chlorine in inactivating poliomyelitis virus.   Identical
dilutions of the same strain and pool of virus, when exposed
to 0.5 to 1.0 mg/i of chlorine and 0.05 to 0.45 mg/i of ozone,
were devitalized within 1.5 to 2 hr by chlorine, while only
2 min of exposure were required with ozone.

    Majumdar et al . (409) also studied the inactivation of
polio virus by ozonation and concluded that the inactivation
is not totally complete.  Results are summarized in Table 49 .


        TABLE 49  .  SURVIVAL OF POLIO VIRUS IN
	OZONATION CONTINUOUS FLOW STUDIES (409)	

                   Ozone          Residence       Average
 Type of        Concentration        Time        Survival
Mastewater         (mg/£)            (min)        (percent)

Primary
 wastewater         0.84             8.0            1'.820
                    1.47             2.0           '0.016
                    4.44             1.0            0.006

Secondary
 wastewater         0.79             8.0            2.055
                    1.77             2.0            0.013
                    5.05             1.0            0.006


      Pavoni and Tittlebaum  (508) recently studied  ozone
disinfection  of viruses  in  the  Fort  Southworth  Pilot  Plant
of the Metropolitan Sewer District  in Louisville.   Using
F2 bacteriophage  as the  model virus, they  demonstrated  virtually
100  percent inactivation efficiency  in  the secondary  effluent
after a  contact time of  5 min at a  ozone dosage of  approximately
15 mg/i  and a  residual  of 0.015 mg/i .  Of particular  interest
was  the  observation that the  rate of inactivation was  greater
for  F2 bacteriophages  than  bacteria.   In addition,  the  following
conclusions were  reached:

      1.   F2 virus concentrations were  shown  to  be  unaffected
          by the flow or  mixing  of  the  ozone  reactor.
                               95

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     2.  F2 virus was inactivated with virtually 100 percent
         efficiency after a contact time of 5 min at a total
         ozone dosage of approximately 15 mg/a and a residual
         of 0.015 mg/a .

     3.  E. coli bacteria and F2 virus were inactivated with
         virtually 100 percent efficiency after a contact time
         of less than 15 sec in the absence of ozone-demanding
         material .

     4.  An extremely small number of viral particles was
         observed in effluent studies.

     5.  Oxidation by ozone appears to be the mechanism of
         kill  for bacterial cells and viral particles.  Ozone
         is theorized to act as a general oxidant causing
         cell  lysis and the release of soluble COD.

     Mercado-Burgos et al.  (444) examined the effect of ozone
on Schistosoma ova, concluding that the process was  ineffective
                              96

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                               SECTION  7

                           LAND/GROUNDWATER
   INTRODUCTION
        Hundreds  of  municipal  and  industrial  wastewater  treatment
   plants  dispose  of their  effluents  to  the  land,  as  illustrated
   in  Figure  2  .  Thousands  of  wastewater  lagoons  percolate
   effluents  into  the  ground.  Millions  of  septic  tank  systems
   leach  their  wastewater  into the  ground.   Most of these  waste-
   waters  travel  through the  soil  and  eventually reach  groundwater
   aquifers.  Unplanned groundwater recharge with  wastewaters,
   therefore, must be  recognized as occurring on a  large scale.
MUNICIPAL 6.INDUSTRIAL
  WASTEWATER LAND
      DISPOSAL
                              WASTEWATER
                                 PONDS
SEPTIC TANK

  SYSTEMS
             USEABLE GROUNDWATER  AQUAFERS
             Figure 2.  Unplanned wastewater reuse exists
                        for many groundwater supplies.
                                  97

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      The  present  interest  in  planned   regulated wastewater
 reuse  projects  is  bringing  into  focus  an  informal  practice
 which  has existed  "in  the  closet"  for  a long  time.  The question
 is not whether  wastewater  reuse  is acceptable, but rather how
 best to control what is an  existing practice.

      Groundwater recharge with treated municipal wastewater is
 accomplished by either  planned or unplanned  processes.  Planned
 processes consist of two basic methods (Figure  3  )   The
 simplest and most widely used consists of conveying'the treated
 effluent to shallow spreading basins and allowing the water to
 percolate through the soil to the groundwater.  The second
 planned method consists of conveying the effluent to a well
 field and injecting the water directly into the aquifer.  The
 major intent of these formal processes is  to replenish ground-
 water basins, to establish saltwater intrusion barriers in
 threatened coastal  aquifers, or to provide further treatment
 for ultimate extraction and reuse.

      Unplanned  recharge, as previously  noted, accounts  for much
 greater amounts of wastewater reaching groundwaters and
 includes  percolation  from  irrigation  and  holding  ponds and
 leachate  from septic  tanks.

      Many  variables affect  the potential  for a public  health
 hazard  from  land disposal.   These include:

      •   The  characteristics  of the  wastewater disposed;

      •   The  rate of waste  application;

      •  The  hydrogeological  characteristics  of the
        disposal  site;

      •  The  method of disposal, e.g.,  crop  irrigation,
        land  spreading,  percolation ponds,  sanitary
        landfill, etc.;

      •  Proximity of public  access;

      •  Utilization of groundwater  potentially
        affected; and

     •  Local climate.

     The above listed variables are not mutually exclusive-
they interact in many ways to  influence the  rate and extent
of transport of  contaminants from each source and to influence
the importance of each potential pathway.  It  is beyond the
scope of this report to delve deeply into the science of waste
application technology.   This subject is being researched


                               98

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                                 SHALLOW BASINS
                                                                 GROUND
TREATED

WASTEWATER
                                                       w _     %****•'  *»,

                                                       • «Q/>tt°0.'  '
   e o» . o '° oe9 o o 0°  " o  ••


   °a?-. 'o0o0:'o<>°a0'\'°>0-*o°°o°°
„" 0 C.O°o0oOo0o  • ° 0 •. °e

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                                    ±
                                 ,  ° . o ' o<>
                                  O o  0 , ,
   M  O    V

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 '" °o O ° o«"0
) 0 0  0 «»  t 0
                                                     -a—«r
                                                                 GROUND
                                              c°o' C

                                              o . o 0~ 0~ O ~ O
' " "0°0- o  • 00,0 0.0<.

'-•-"a o°'0V o'»'*\
                                                 0. 00^0
                                                                          0 ,
                           GROUNDWATER  AQUAFER
                  PLANNED RECHARGE BY DIRECT  INJECTION
                 Figure 3.   Methods of planned  recharge.
                                      99

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heavily by the EPA and other agencies to establish guidelines
for the safe land disposal  of effluents.  This report will,
however, discuss the current knowledge about associated
potential  public health problems.

     Literature reviewed concerning wastewater disposal to
land has centered on groundwater elemental  and biological
contaminants, and water quality parameters  providing plant
nutrients, such as nitrogen and phosphorus  forms.   The increased
use of wastewater application to land has created  a need for
increased  research into the dynamics of wastewater contaminants
in soil systems.  It is necessary  to study  the capabilities of
these systems to destroy, neutralize, remove, concentrate, or
otherwise  affect applied wastewater contaminants.

     A number of factors determines the degree to which ground-
water may  be contaminated by wastewater that is applied to
land.  Depth to the groundwater table and distance to an
extraction point affect residual levels of  phosphorus, bacteria,
and other  constituents for which removal appears to be a func-
tion of travel distance.  Soil  characteristics, native ground-
water quality, assimilation capacity of the aquifer, and method
of waste application also determine groundwater degradation
and consequent health problems  (568).  Cation exchange and
adsorptive capacities important in the removal of  metal ions
and viruses and of trace organics  and solids are determined by
soil composition.  Porosity regulates infiltration rates to
some extent, affecting contaminant residence time  in surface
layers.  Residence time may, in turn, determine aerobic or
anaerobic  conditions.

     Total groundwater volume cannot necessarily be considered
an effective diluting agent.  Uniform diffusion of recharged
water cannot be guaranteed, and water quality may  vary
considerably both in area and in depth.

WATER QUALITY PARAMETERS

     Research in this area has  been principally concerned with
nitrogen and phosphorus forms entering groundwater as a result
of land application of wastewater.  Removal of suspended solids
from wastewater effluent has also  received  attention.

     The problems and transformations associated with nitrogen
forms in soils are relatively well known.  Organic nitrogen
and ammonia, when applied to soils under normal aerobic condi-
tions, are rapidly converted by nitrifying  bacteria to nitrite
and nitrate.  Both of these anionic forms move through soils
in percolating water with little difficulty.  Under anaerobic
soil conditions, on the other hand, the process of conversion
to nitrite and nitrate is inhibited.  Ammonium ions and free
                              100

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 ammonia  persist  and  are  held  near  the  soil  surface by adsorption
 onto  soil  particles,  by  cation  exchange  reactions, or by fixa-
 tion  in  clay  lattices.

      In  an acidic  environment,  nitrite has  been  found to react
 with  secondary  amines to produce  nitrosamines.   These compounds
 have  recently been labeled  carcinogenic, teratogenic, and
 mutagenic.  The  health hazards  associated with  nitrite  and
•'other forms of  nitrogen  in  drinking  water and  crops  have been
 delineated by the  U.S. Department of Agriculture (663).

      The most definitive study  of nitrogen  removal  by  land
 application of  wastewater effluent was conducted by  Herman
 Bouwer at Flushing Meadows, Arizona  (  73).   He  found that  short
 flooding periods (two days  flooding  followed by five days  dry-
 ing)  did not provide sufficient time to develop the  anaerobic
 conditions for  nitrate denitrification.  A  longer flooding
 period of ten days followed by  two weeks of drying proved  to
 be more favorable.  With this schedule, oxygen in the soil  was
 depleted during flooding, causing nitrogen  (in the ammonium
 form) to be adsorbed by the clay and organic particles.  Flood-
 ing was stopped before the cation exchange  complex in the  soil
 was saturated with ammonium.  Upon drying,  oxygen entered  the
 soil, and ammonium was nitrified under aerobic conditions  to
 nitrate.  Concurrently, some of the nitrate formed was denit-
 rified, in micro-anaerobic pockets in the otherwise aerobic
 upper soil zone,  to  nitrogen gas that escaped to the atmosphere.
 When flooding was resumed, if the basins were immediately
 flooded to a depth above 1 ft, the nitrates were quickly
 leached out  of  the top  few feet of the  soil to  groundwater.
 However,  if  initial  flooding was shallow (a few  inches deep),
 the  lower  head  allowed  a low infiltration rate,  a larger nitrate
 retention  time  in the microbiologically  active  soil zone, and
 further denitrification.   At these  lower initial hydraulic
 loading rates,  nitrogen  removals were  as high as 80 percent.
 However,  if  high  application rates were  consistently maintained,
 nitrogen  removal  was only  30 percent  with  a peak nitrate surge
 to the  groundwater  after the start  of  each  new  flooding cycle.

       A  study by Preul  (532)  in  1966 provided the following
 observations of the  movement and  conversion of  nitrogen in
 soil  and  the potential  dangers  of nitrate  contamination:

       1.   Biological  oxidation  is  the  dominant  mechanism
           affecting  ammonia nitrogen  as  it  passes through
           the soil.   This action  initially  occurs at a
           high  rate,  and to a  large  extent,  within  several
           feet  of  the point of  release of the  septic tank
           effluent,  if soil conditions are  well  aerated.
                                101

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     2.  Nitrate contamination of groundwaters is a
         serious threat from shallow soil adsorption
         systems.  High concentrations of ammonia
         nitrogen in septic tank effluents are quickly
         nitrified to high concentrations of nitrate,
         which pollute the groundwater.  Dilution from
         groundwater or soil moisture and possibly
         denitrification aid in the deterrence of
         ni trate.

     3.  The effectiveness of adsorption in deterring
         the travel of nitrogen is limited, because of
         the rapid conversion of ammonia to nitrate.
         Laboratory experiments have shown that ammo-
         nium can be readily removed in soil by adsorp-
         tion; but, under aerated soil  circumstances,
         nitrification of these ions occurs before the
         flow can contact a sufficiently effective
         volume of soil.

     Similarly, results of a study by Chapman et al. (115) have
shown that, in Texas, irrigation with a sewage effluent was a
potential source of nitrate pollution of the local groundwater.
The results indicated that nitrification of ammonia nitrogen
in the effluent is rapid  and complete,  taking place within the
top 3 ft of soil.  It was concluded that substantial amounts
of nitrate would not be fixed by the soil and that, at a 3-in
per week application rate, appreciable  amounts of high nitrate
water would percolate to  the groundwater.  Selective crop
production of grains and  grasses having high nitrogen uptakes
(corn, bermuda grass, oats) was deemed  the most effective
method of protecting the  groundwater.

     Short daily flooding schedules evidently result in highly
efficient nitrification to nitrate.  Me Michael and McKee (441)
reported data from test basins in the Whittier Narrows and the
Rio Hondo spreading grounds near Los Angeles, California.
These basins, equipped to collect water at 2-, 4-, 6-, and
8-ft depths,  received treated wastewaters on a daily basis
using a short period of flooding and a  longer period of drying.
This cycle ensured completely aerobic conditions.  Studies
indicated that almost all the nitrogen  had been converted to
the nitrate form at depths of 8 ft.

     Intermittent and continuous spreading of secondary effluent
at the Hyperion Treatment Plant (572),  in Southern California,
resulted in the nitrogen  transformations shown in Table  50.
                              102

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      TABLE  50 .  NITROGEN TRANSFORMATIONS RESULTING FROM
                 DIFFERENT SPREADING TECHNIQUES (572 )
 I.
      Under continuous
      spreading:

         Effluent applied
II.
         Percolate  from  7-10  ft
         below  ground  (mg/-€)

       Under  intermittent
       spreading:

         Effluent  applied
Organic-N  Ammonia-N  Nitrate-N

 7.1-8.5   15.5-17.5  0.2- 0.8


 1.2-2.7    8.7-18.5  5.2-18.1



Organic-N  Ammonia-N  Nitrate-N

 2.3-3.6    4.9-27.9  0.1-14.2
         Percolate  from  7-10  ft
         below ground  (mg/£)
 1 .1-2.1
                                           0.0- 0.7  8.4-22.4
     A study (  572 )  conducted at the sewage farm in  Arroyo  Grande,
California, indicated the pulse-like effect of intermittent
spreading on the nitrate level  in the percolate.  During weekly
flooding of the field with settled sewage effluent,  the upper
foot of the soil adsorbed 2,840 Ib of organic and ammonia nitro-
gen/ac.    As the fields drained and were exposed to oxygen, this
adsorbed nitrogen was rapidly converted to nitrate,  resulting
in nitrate levels of 1,000 to 2,000 mg/£ in the soil solution
of the top foot.  Consequently, the subsurface drainage water
exhibited pulses of higlj nitrate concentration
began.  After all the nitrate was leached from
the applied wastewater, the nitrate content of
returned to a low level.
                                             when flooding
                                             the topsoil by
                                             the drainage water
    When the South Tahoe Public Utilities Department sprayed
treated sewage on forested hillsides in the fall of 1963,
nitrogen removals by the soil mantle were more than 65 percent.
The removals dropped to 26 percent  in the winter when the ground
was frozen.  Significant amounts of ammonium  ion were present
in the upper 4  in of  soil, but  nitrate  levels were  low
at all depths.   The removal  of  nitrogen was attributed to the
denitrification  in the  soil  mantle  under anaerobic  conditions
(572  ).

      The California State Health Department ( 572)  reviewed
nitrogen removals and management at a number  of well-injection
waste disposal/recharge systems.   Results of  a  six-month study
on the injection of slow  sand filter effluent are shown
in Table  51 .
                               103

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         TABLE 51 .   NITROGEN  TRANSFORMATION  IN  RECHARGE
 	     AQUIFER.  MG/l  ( 572 )	

                      Organic-N   Ammonia-N  Nitrite-N   Nitrate-N

 Natural  water in
   the  aquifer
 Filter effluent
   before  injection

 Recharged water  in
   aquifer, 20 ft
   from injection well

 Recharged water
   mixture in  aquifer,
   500  ft  from injec-
   tion well
,4-. 5


 2.2



 1.4
 .2


1.5



1.2
  .9
 .8
0.0


 .01



 .21
.4-4.8


  21 .3



  18.2
 .003
   6.1
     As can be seen from this table, intermittent spreading
techniques maintained aerobic conditions in the soil, making
possible the oxidation of ammonia and organic nitrogen to nitrate.
Under continuous spreading, anaerobic conditions prevailed, and
ammonia was still present in significant concentrations at a
7- to 10-ft depth.

     When a low-rate application system is used, the amount of
nitrogen applied to soil with sewage effluent is not much more
than can be removed by crops, according to Bouwer (72 ).   A low-
rate system involving application to wheat at 2.5 and 5 cm/week
was cited.  At the lower application rate, 92 percent of  the
nitrogen in the wastewater was removed in the soil,  while at the
5 cm/week rate, 60 percent was removed.  On the other hand, when
animal waste slurries or other wastewater with a relatively high
nitrogen content are applied, the amount of nitrogen supplied
may far exceed that which can be utilized by crops.   To obtain
significant nitrogen removal under these circumstances, Bouwer
suggests that the system be designed to stimulate denitrification
in the soil.  He cites an instance where this was done by install-
ing an artificial barrier to water movement at a depth of 2 m,
causing the formation of an anaerobic region.  Ammonia and organic
nitrogen in applied wastewater were converted to nitrate  in the
upper, aerobic region of the soil, which was then denitrified
in the lower, anaerobic zone.  The system removed 96 to 99 percent
of the total nitrogen applied at rates of 1 to 2 cm/day.
                               104

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     Analysis  of data  in  Table  50  indicates that the  decay
of nitrate in  the aquifer was  due to some extent to  denitri-
fication,  as well as  dilution.   Considering such decay,  the
nitrate nitrogen level  was expected to fall to 10 mg/£ before
traveling  a distance  of 500 ft  in the aquifer.  Further  tests
revealed an anaerobic,  microbiological ly active zone  in  the
aquifer in the vicinity of the  injection well.  During the
tests, nitrate was largely removed by microbial denitrifica-
tion within 150 ft of the injection well.

    In summary, data  indicate  that, under proper management
conditions, land application of wastewater effluent  offers
the potential  to efficiently remove nitrogen from wastewater
and protect groundwater from nitrate contamination.   The most
successful programs stressed an appropriate flooding/drying
schedule to promote both aerobic nitrification and anaerobic
denitrification processes, in  order to ultimately convert
ammonia nitrogen in the wastewater to nitrogen gas.   However,
if not properly managed, a definite danger exists of polluting
groundwater resources with excess nitrates.

    Recent studies of land application of wastewater effluent
indicate that the soil  system  is highly efficient in removing
phosphates from wastewater.  Phosphate removal is both a
function of soil composition and travel distance.  In most
soils, phosphorus not taken up by plants is immobilized due
to the adsorption of phosphate onto the soil.  Adsorption -!s
followed by precipitation into various forms  of calcium
phosphate if the soil is basic (72  ).  These  reaction products
are sufficiently insoluble, so that phosphorus is held in the
upper few centimeters of most soils,  and very  little phospho-
rus moves into the groundwater (388).  However, in the case
of acidic, sandy soils with no iron or aluminum oxides, little
phosphate is fixed.  Thus, it may be  necessary to remove
phosphorus from wastewater before its application to such
soils  (72  ).

    Hook,  Kardos, and Sopper (299)  reported that, under proper
management, most of the  phosphorus  in wastewater remains in
the soil at the  disposal  site or  leaves as a  nutrient in
harvested crops.  They found that soils differed in  their
abilities  to retain phosphorus.   In a heavy-textured soil high
in  iron and aluminum oxides and  hydroxides  (sesquioxides),
phosphorus from  effluent  irrigation did  not increase  in the
soil  below a depth of 1  ft after  7  yr of  irrigation.  In a
light-textured  soil with  half as  much sesquioxides,  phosphorus
content increased  to a depth of  3 ft  after 6  yr of treatment.

    Phosphorus  removals  at  Flushing Meadows,  Arizona  (73 ),
were  found  to  be  basically dependent  upon  the distance  traveled
by  the  wastewater  through  the soil.   The  chief removal mechanism


                               105

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 was  precipitation  as  calcium  phosphate  or magnesium ammonium
 phosphate,  since the  soils  tested  contained  little iron,
 aluminum oxides, or other phosphate fixing materials   Under-
 ground travel distances of  30 ft produced 50 percent reduction-
 distances of several  hundred  feet  were  found to be sufficient  '
 for  90 percent phosphorus removal.  However, the capacity of
 the  soil to remove phosphorus decreased after the start of the
 project, holding stable at  approximately 50 percent removal.

     The fact that soils gradually  lose their capacity to adsorb
 phosphates over long-term application is substantiated by
 Barrow's detailed analysis of this phenomenon (30).   He
 concluded that previously applied phosphate had been  converted
 to a form that was  occupying phosphate adsorption sites, thus
 reducing the capacity  of the soil to further adsorb phosphate.

     Continuing studies at Lake George, New York ( 22  ), have
 shown that significant amounts of nitrates appear to  reach
 the waters  tributary  to the  lake.  However,  the wastewater
 land treatment system  appears  to  remove  essentially all  phos-
 phorus,  thus reducing  the  potential for  algal  bloom in  the  lake.

     Dugan et al.(185), in  their work on  land  disposal  of
 wastewater  in  Hawaii,  noted  that  phosphorus  removals  of over
 95 percent  within a 5-ft  depth of percolation were  obtained
 when secondary wastewater  was  applied  to grassed  areas.

     Suspended  solids are  removed  very  effectively  by  land
 application  systems.   In  fact,  one  problem  encountered  in the
 spreading of wastewater  is that nearly all  suspended  solids
 are  filtered out in the  top  few inches of  soil.   This can cause
 clogging  of  soil pores  and reduction of  infiltration  rates.
 There  is  no danger of  groundwater contamination  in  applied
 wastewater from suspended  solids.   Literature data  on suspended
 solids are not extensive,  because experience  has  shown  land
 application to be capable  of removing  virtually all solids at
 the  surface.  A study  at Whittier Narrows, California (572),
 showed suspended solids removal,  due to  percolation, of 95 per-
 cent.  At Flushing Meadows ( 73 ),  the suspended solids concen-
 tration of the percolate was essentially zero, even though
 the  solids in the wastewater applied reached  100 mg/£.  Similar
 findings were reported at  Lake George  (  22 ), where virtually
 all  BOD and suspended  solids were removed from percolated
 effluent.

    Results from a spray i rrigation and  runoff system used to
dispose of a cannery waste (  45 )  showed that even with a run-
off-type system, suspended solids  removals averaged 97 percent
Dugan et al. ( 185)  reported  similar high suspended solids
removals with application of  secondary effluent to Bermuda
grass in Hawai i.
                               106

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ELEMENTAL CONTAMINANTS

     Municipal  wastewater contains small amounts of nearly all
metals.  The degree to which a particular soil  will protect-
underlying groundwater through removal of contaminants is
primarily determined by the chemical and physical composition
of the soil.  Removal can occur through such processes as
precipitation of solid phases, ion exchange, and adsorption.
These processes are in turn controlled by soil  pH, the
oxidation/reduction potential, clay content, the presence and
type of organic material, and the extent of soil saturation.

     The general nature of reactions of sewage wastes with
soil is well known.  With time, wastes applied to  land are
broken down, and the dissolved constituents become part of
the soil solution.  Released cations can exchange  with those
already on exchange sites in the  soil.  Metals as  ions or  in
the colloidal state can be adsorbed onto soil surfaces.  When
the levels of ions  in solution exceed  the solubility  of
corresponding solid phase compounds and minerals,  those
compounds can precipitate.  When  the  solubility  of solid  phase
compounds and minerals exceeds the  levels of corresponding ions
in  solution, the compounds can dissolve.  Constituents are also
ingested by  soil microorganisms and incorporated into soil
organic matter.

      Ions that  are  not removed by any  of these  processes,  but
that  remain  in  the  soil  solution, are  available  for  uptake by
plant  roots  or  leaching  by water  moving  through  the  soil
profile.  Lindsay  (388)  studies the composition  of the soil
solution, concluding  that  it  is controlled  by  the solubilities
of  solid  phases.   Thus,  precipitation and dissolution reactions
determine the  activity of  ions  in solution, which in turn
governs  ion  exchange.

      Lindsay (388)  also  recognized the importance of the
formation of metal-organic  complexes  and chelates in increasing
the solubility  and  mobility  of  metals in soils.   Brown (79 )
stressed this  point.   He found  that it is  misleading to predict
the availability of metals  in soils from their solubility in
distilled water.  He cites  evidence that plant uptake of metal
 ions  could  not be predicted  by  the water solubility of the
 solid compounds.  This may be because the soil  solution in the
 vicinity of roots, unlike distilled water,  is  mildly acidic  and
 contains organic metal-complexing agents (388).

      All of the trace elements for which water quality criteria
 have been established may occur  as either soluble or insoluble
 metal-organic  complexes  (615).    Low molecular weight organic
 molecules tend to increase the penetration of complexed metal
 ions into the soil, while high molecular weight molecules and
 their complexed ions may be filtered  out by the  soil  (72  ).

                               107

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 The chemistry of the metal  organic complexes is  complicated,
 and present knowledge of organic forms  of the elements  is
 insufficient to generalize.   Where concentrations  of  trace
 elements  in soil  solutions  are  in  excess  of  those  predicted from
 inorganic  solubility product  considerations,  the element is
 thought  to occur in  organic form.   Because of this  lack of know-
 ledge,  the literature discusses  mainly  the chemistry  of inor-
 ganic  forms.   This  is unfortunate  because most of  the metal
 ions  in  wastewater  and sludge probably  occur in complexed
 form.


      Most  metals  are less mobile under  aerobic and  basic soil
 conditions than they are under  anaerobic  and  acid  conditions
 (72 ).   The neutral  water extract  of  soils contains less
 heavy metals  than acidified extracts  of the  same soils, indi-
 cating  the importance of the  pH  factor  in influencing the
 mobility of metals  (533).   Lindsay (374)  cites evidence that
 for zinc and  copper  there is  a  100-fold increase in ionic
 activity for  each unit  decrease  in soil pH.   Normally insoluble
 metals may become mobilized in  the event  of  a  change  in the
 characteristics  of  percolating water, such that acidic or
 anaerobic  conditions  occur.

     The removal of  metals by ion  exchange or  adsorption depends
 upon the availability  of exchange  and adsorption sites in the
 soil as well  as on the  factors  (ionic activity and pH) just
 discussed.  Therefore,  the clay  content of the soil is important;
 clay soils  provide more  exchange and adsorption capacity than
 sands and  gravels (552).  A correlation also exists between the
 form in which the elements occur in solution and their removal
 by exchange or  adsorption.  In general, elements that occur in
 solution as anions or neutral  molecules pass through  soils
 more readily  than do elements  that occur  as cations.  Inorganic
 arsenic, selenium, and fluorine  in aerated soils occur as
 anions or  neutral molecules.  Although there are exceptions
 (depending upon the chemistry  of the system),  inorganic  cadmium,
 copper, chromium, lead, mercury, silver,  and zinc most commonly
 occur in fresh waters and soil solutions  in the inorganic
 form as cations (615).

     Only one reference was  located that  provided experimental
data on cadmium in relation  to wastewater  applied to land.
At Flushing Meadows, Bouwer  (  73  ) found  that  cadmium in  waste-
water  applied to land in shallow basins  showed very little  change
due to migration through the soil.   The  cadmium concentration
dropped  only slightly from 7.7 yg/£ to 7.2 ug/£.   Aerobic
conditions  and alkaline pH prevailed in  the  soil  studied.   A
study  (615) by the California  State Water  Resources Control
Board  (CSWRCB) reviewed available data on  soil  reduction  of
cadmium  in  effluents, concluding that  information  is  not
sufficiently detailed to allow adequate  evaluation  of  cadmium

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concentrations in water reaching g>oundwater basins.   According
to the study, it must be demonstrated that a particular soil
is able to reduce the concentration of cadmium to a level  that
is acceptable for drinking water.  Otherwise, the study advised
against the use of wastewater effluents with concentrations
above this limit for groundwater recharge operations  involving
percolation through soil.

     Bouwer's work at Flushing Meadows ( 73  ) found that the
copper concentration of applied wastewater was reduced about
86 percent by passage through the soil.  This removal occurred
rapidly, usually in the first 30 ft of downward flow.

      Iron and manganese in wel1-oxidized soils are characterized
by the formation of highly insoluble oxides  and hydroxides.
However, at  low  pH and  under reducing  conditions,  these metals
can  be solubilized and  become mobile in  the  soil as  Fe^+ and
Mn2+.  Amramy  (15) conducted a  study  of sewage lagoon effluent
spreading on  sand dunes.  He found that  after a subsurface
travel distance  of 8 m,  the  concentration of  iron  in  the waste-
water  actually  increased  from 0.28 mg/£  to  0.57 mg/£.  The
manganese concentration increased  from 0.08 mg/£ to  0.19 mg/£
after  25  ft  of  travel  through sand.  Wesner and  Baier ( 685)
found  a similar  phenomenon when  tracing  the underground move-
ment of wastewater  after  injection.   Over a travel distance  of
400  or 500  ft,  the  concentration of  iron did not  change.
Manganese  concentrations, on the other hand, increased up  to
300  percent  in  the  first  100 ft of subsurface travel.  Anaerobic
conditions,  favoring  formation  of  soluble manganese  compounds,
are  mentioned as the  possible  cause  of the  large increase.
These conditions are  most likely caused by  biological oxidation
depleting oxygen near the point of injection, thus causing the
reduction of manganese to soluble  forms.  However, after
greater travel  distances and the return to  aerobic conditions,
 the  manganese may revert to  insoluble compounds and  be removed
from the  migrating water.

      Ragone, Vecchioli, and  Ku (535) reported on deep well
 recharge  experiments conducted in  Nassau County, Long Island.
 Tertiary  effluent was recharged by a deep well  into the Magothy
 aquifer,  the primary water supply  source for Nassau County.
 As of September 1972,  12 recharge  tests had been run since the
 inception of the recharge program  in  September 1968.  Although
 the iron  concentrations  of reclaimed  and native water averaged
 0.44 mg/£ and 0.24 mg/£,  respectively, the  iron concentration of
 the mixed (native and  reclaimed) water  at  times exceeded 3 mg/£.
 The authors mentioned  several sources that  could  account for
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 the  increase  in  iron  concentration,  but the most probable source
 was  the  pyrite native  to  the  Magothy aquifer.  During recharge,
 the  natural reducing  condition  in the aquifer was replaced by
 a  progressively  more  oxidizing  environment.  The initial
 response  to this  change was the oxidation of pyrite, which
 released  Fe+2, 504-2,  and H+  into solution.  Eventually, ferric
 hydroxide  precipitated, and the Fe+2 concentration decreased.
 The  exact  oxidation mechanism apparently involved inorganic
 and/or organic constituents in  the reclaimed water, because
 water from the public  potable water supply system caused no
 increase  in iron  concentration when injected into the aquifer.

     The  Flushing Meadows study by Bouwer (73 ) contained data
 on the reduction  of lead by soil infiltration.  Bouwer found
 that the wastewater concentration of lead decreased by 20 percent
 after significant travel distance underground.  Apparently, a
 small portion of  the lead was tied up rapidly (within 50 ft),
 while the majority was unaffected by further travel.  It should
 be noted, however, that the soil examined in these experiments
 was  a sand with limited adsorption and exchange capacity for
 many trace elements.

     Both mercury and zinc form insoluble compounds in soil,
 lowering the activity of the ions in solution so that little
 movement occurs.   Mercury is particularly insoluble as phosphate,
 carbonate, or sulfide.  However, under low pH conditions, the
 metals may become mobilized.  They can also form soluble
 complexes that affect their mobility under certain circumstances
 (388).  At Flushing Meadows (73 ), underground percolation
 through 100 ft of sand produced 40 percent removal of mercury
 and approximately 58 percent removal of zinc.  Further travel
 produced no further removal  of mercury but reduced the zinc
 concentration to  about 20 percent of that in the applied waste-
water.  The final concentrations of mercury and zinc were
 .00014 mg/£ and .037 mg/l, respectively.

     In conclusion, the information garnered in this study of
 the literature is inadequate to define fully the chemical
behavior of elemental contaminants in the soil and their fate
as they percolate through the unsaturated zone.   The CSWRCB
 recommended, on the basis of its literature review (615 ), that
wastes containing concentrations of certain metals above those
acceptable for drinking water supplies should not be applied -to
land, unless it can be demonstrated that contamination of
 groundwater does   not occur.

BIOCIDAL CONTAMINANTS

     Use of chemical pesticides in agriculture generated
many studies of, the potential  harmful effects of these compounds
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on land, crops, surface water, and groundwater.   However,  there
is little data available on biocides in municipal  wastewater or
on the potential  dangers of groundwater contamination through
land wastewater application operations.  This lack of informa-
tion is understandable considering the minimal  role that munici-
pal wastewater plays in transporting biocides to the land  and
groundwater.   Biocides come in contact  with the land through a
number of activities, primarily by direct application to the
land for pest control.  Return irrigation water, and spills and
wastes from pesticide manufacturing operations  also bring
biocides in contact with the land.

     The reactions of pesticides with soil has  received limited
attention in  the literature.  Volatilization, chemical  degrada-
tion, and absorption by plant roots and seeds apparently remove
a small portion of pesticides reaching the soil.  A more signi-
ficant process for pesticide removal may be microbiological
degradation.   Although this process is very slow in some cases,
often taking  several years, microbiological degradation accounts
for the breakdown of a remarkable variety of organic compounds.
Pesticides that are not removed from the soil column or broken
down by these processes may be available for leaching into
groundwaters.

     Gerakis  and Sficas (239) reviewed the literature on pesti-
cide.degradation and leaching   They reported that the most
important factors involved in these two processes are soil
temperature and moisture, organic matter and clay content,
soil management practices, pH, and species and  population
density of microorganisms present.  The presence of organic
matter and clay in the soil appears to be positively correlated
with adsorption of pesticides onto soil particles.

     Van Bladel and Moreale (658) studied herbicide adsorption
onto clay minerals.  They found that adsorption increased
with the polarizing power of the exchangeable cation, and
concluded that adsorption appears to be one of  the most impor-
tant factors  in reducing pesticide removal from soil layers
by leaching.

     Gerakis  and Sficas (239) cite evidence that pesticides
differ in their mobilities in the same soil.  One study showed
that (1) acidic compounds are relatively mobile, (2) phenyl
ureas and triazines are of intermediate to low  mobility, and
( 3 ) organochlorine compounds and organic cations are least
mobile.  Further data that were reviewed supported the conclu-
sion that under normal agricultural practices and rainfall,
it is very unlikely that pesticides may be leached deeply
enough and in such quantities as to cause appreciable contami-
nation of groundwaters.
                              Ill

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      A  California  State  Water  Resources  Control Board report
 (615) mentioned  that  pesticides  are adsorbed by soil clays,
 iron  aluminum  oxides, and especially by  organic colloids, and
 that  they are  susceptible to microbial decomposition.  However,
 the amount of  biocides in average municipal wastewater was
 found to be so minimal that the  spreading of municipal waste
 on land offers extremely low potential for groundwater biocide
 contamination.

 SYNTHETIC/ORGANIC CONTAMINANTS

     One of the most intensely debated questions regarding
 land application for treatment and/or disposal  of municipal
wastewater concerns the problem of residual organic contami-
 nants.  Refractory organic compounds may survive conventional
 treatment processes and penetrate through the soil to contami-
 nate groundwater supplies.  The controversy centers around
 the fate of residual organics within the soil systems, includ-
 ing such issues as the synergistic effects between organics
 and inorganics or other groundwater and soil  constituents, or
 conversion of safe organics  to hazardous compounds in the soil.
 Despite this controversy, no literature was found concerning
 groundwater pollution by the synthetic/organic  contaminants
 in municipal  wastewater as a result of land application.

     The absence of literature concerning the movement through
 soil  of synthetic/organic contaminants is not surprising, since
 the specific organic makeup  of wastewater is  unknown.  Some  of
 the chemicals of concern (PCB's, polycyclic aromatics, and
other chlorinated hydrocarbons, etc.) have low  solubilities  in
water in comparison with vapor pressures.  As a result,  there
 is a distinct possibility of vaporization when  wastewaters
 containing these chemicals are applied to the land surface.

     The California State Water Resources Control  Board  (615)
cited a study carried out in Colorado that compared the  nature
of the soluble organic material in the soil profiles under a
feedlot and under grassland  with selected ground, well,  and
river waters.   It was concluded that the major  portion of the
soluble materials in all  the waters was polymeric.  The  soluble
organics under grassland were essentially the same as those
under the feedlot, although  phenols were present in greater
abundance in the manure and  surface soil of the feedlots.  About
13 percent of the soluble material in the soil  profiles  was
carbohydrate (polysaccharides), and much of the remainder,
based on IR spectra and reductive degradation procedures,
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appeared to be polymerized aromatic structures.   This  report
by the CSWRCB interpreted these observations  to  indicate  that
the soluble organics under wastewater-treated soils  would  be
similar to those under feedlot manure or grassland.
BIOLOGICAL CONTAMINANTS

     Most available data suggest that
other biological pathogens present in
or inactivated by percolation through
  virus,  bacteria,  and
  wastewater  are  removed
  soil.
     The California State Water Resources Control  Board study
(615 )  provides a summary of the fate of viruses,  bacteria,
protozoa, and parasitic worms in wastewaters  applied to land.
The summary states that most of these pathogens prefer warm-
blooded animals as their habitat and do not flourish in the
soil environment.  When introduced into soils, the pathogens
do not  compete well with the vast number and  variety of normal
soil inhabitants and are subject to attack by antagonistic soil
species.  The time necessary for their ultimate destruction
varies, according to species and environmental conditions.
A compilation of pathogen survival data in t^e literature is
shown in Table 52  below.
               TABLE  52.  SURVIVAL OF PATHOGENS
                        IN SOILS (615 )
  Ascaris lumbri coides ova
  Entamoeba histolytica cysts
  Salmonella species
  Coliform group organisms
  Q-fever organisms
  Brucella abortus
  Tuberculosis bacteria
  Enteroviruses
2.5 - 7 years
8 days
6 hours
133 - 147 days
148 days
30 - 100 days
6 months
12 days
     The most persistent pathogens in soils appear to be ova,
cysts, and spore-forming bacteria.  The survival of enteric
viruses in soil has not been thoroughly studied.  The dependence
of enteric viruses on specific host organisms for reproduction
suggests that they would not multiply and would not be expected
to survive for a long period of time, although survival may,
at times, be long enough to cause public health concern.
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     Two-and-a-half years of continuous observation was
conducted of wastewater reclamation by landspreading in Lodi,
California (553).  It was found that the MPN of coliform group
organisms, which averaged 1.9 x 10^/100 ml in the wastewater,
was consistently reduced to less than 1/100 ml after 4 to 7  ft
of soil travel.  The average percolation rate was 0.3 ft/day
in coarse-textured Hanford sandy loam.  It was observed that
the number of coliforms penetrating 1 ft or more was essen-
tially independent of the coliform concentration of the
wastewater.

     At Whittier Narrows (441), percolation tests showed that
vertical percolation of wastewater through 4 to 7 ft of soil
is an effective method of removing bacteria of fecal origin,
despite heavy growth of coliforms of soil origin.  The forma-
tion of an organic-microbial slime layer at the water-soil
interface was found to increase the efficiency of the filter-
ing action.

     Results from studies at Flushing Meadows, Arizona ( 73),
show that fecal coliform density was reduced significantly in
the first 2 or 3 ft of travel.  Bouwer found that fecal coli-
form density at a particular depth tended to decrease with
increased flooding time.  The peak bacteria density invariably
appeared immediately after flooding was resumed.   The concen-
tration of fecal coliforms was consistently decreased to less
than 10/100 ml after 100 ft, and to 0/100 ml after 300 ft of
travel.

     A project at Santee, California (569), is famous for
its pioneering work in the reclamation of domestic sewage for
recreational  lakes.  Travel  of secondary effluent through
1,500 ft of very coarse sand was sufficient to remove all
fecal  coliforms.  Sampling showed that most of the coliforms
were removed  in the first 200 ft.

     At Orange County, California (685), tests conducted on
a  well  injection system showed coliform organisms 30 m from
the injection well, but none approximately 80 m from the well.
The results indicated  that fecal coliforms are more easily
removed by underground travel  than other coliforms.  Some of
the other coliforms may have been supported by nutrients in
the effluent.
                              114

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     Results of percolation tests  at Lake George,  New  York
(  535 ), showed again that percolation of applied  secondary
effluent through 5 to 10 ft of soil  in  two different  beds was
sufficient to remove essentially all coliform organisms.

     Browning and Mankin (  83)  reported  an unusual  case of
disease outbreak due to contamination of groundwater  well
supplies by land application of treated sewage.   In Madera,
California, undisinfected  secondary  effluent was used  to  irrigate
a  pasture located adjacent to  a deep well drawing  part of  the
city water supply.  The wastewater migrated through gopher  holes,
filling a construction pit around  the well, and  eventually
flowed into the well itself.

     On the basis of experience and  results of full-scale,
long-term wastewater reclamation studies, the CSWRCB  (615 )
concluded that, although soil  is an  excellent media for removing
bacteria, a small fraction of the  fecal coliform bacteria  there-
in may reach groundwater reservoirs  at  high percolation rates.
Horizontal travel of viable fecal  coliform bacteria in the
aquifer does not appear to occur to  a significant  degree.   The
available data on horizontal travel, however, are  inconclusive.
Further inyestigation of the transport and survival of pathogenic
bacteria in groundwater, therefore,  is  required.

     Research shows that travel through soil removes significant
amounts of viruses, primarily through adsorption.   Adsorption
is influenced by the pH and ionic strength of the soil solution.
The available information indicates  that adsorption of virus
by soil is nearly complete at pH 7 or less, but decreases as
the pH value increases above 7.  This is mainly because the
overall electric charge surrounding both the virus and soil
particles becomes increasingly negative as pH levels increase
and, therefore, mutual repulsion occurs  (615 ).

     It also appears that increasing cationic strength of the
percolating water or soil  solution  increases virus removal.  At
the pH values normally encountered  in wastewater,  viruses are
slightly negatively charged.  The presence of calcium, magnesium,
sodium, aluminum, and other positive ions  in the  soil solution
decreases the potential for negatively charged  soil and virus
particles to repel  each other.  This results in the formation
of soil-cation-virus bridges that immobilize  virions (615).
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     The ionic strength in percolating wastewater is usual.ly
sufficient so that it does not limit adsorption.  In circum-
stances where ionic strength is significantly decreased,
however, desorption of adsorbed viruses may occur.  Organic
matter in wastewater can also compete with viruses for adsorp-
tion sites.  In laboratory studies, when virus-adsorbed clay
particles were washed with distilled water, an essentially
complete desorption and reactivation of viruses took place.
In field conditions, other mechanisms in soil systems may
inactivate or destroy adsorbed viruses before they are subject
to desorption (615 ).  In addition to pH and ionic strength,
the clay and organic matter content of soil evidently influences
adsorption to some degree.  In general, soils of higher clay
and/or organic matter content are more effective in adsorbing
viruses (615).

     Definitive work on virus interaction with soil was conducted
at Santee, California, where extensive studies showed that
percolation through several hundred feet of soil consistently
removed all virus from secondary effluent (569 }.

     Other studies also supported the conclusion that soil
effectively removes viruses.  Viral analyses in Hawaii by Dugan
et al.  (185)  showed that test soils in 5-ft lysimeters were
completely effective in removing viruses.  Brief tests at
Whittier Narrows, California (441), achieved complete removals
of Sabin Type III polio-virus vaccine.  Although 250 plaque-
forming units (PFU) of enteric viruses/t were present in the
applied wastewater, no measurable concentrations were found below
2 ft in the percolate.

     In 1974 at Flushing Meadows (73 ), virus analyses were
performed bimonthly to determine the fate of viruses in the
soil  system.   Secondary effluent was allowed to infiltrate into
six parallel  horizontal basins consisting of 60 to 90 cm of
fiae loamy sand underlain by several coarse sand and gravel
layers  to a depth of 75 m, where a clay layer begins.  Observa-
tion wells were installed in line across the basin area.  No
viruses were detected in any of the wells at any time during
each flooding period.  Gilbert et al. (247) stated that the
failure to detect viruses in the wells indicates that the virus
count was reduced by at least 99.99 percent within 3 to 9 m
of basin soil.

     Romero ( 553 ) reviewed the studies performed for the
Department of the Army on sands ranging in classification from
silty sand to coarse-granite alluvium.  Results indicated that
the bacterophages Tl , T2, and 65 are more effectively retained
in the finer sands, particularly in those containing a relatively
high percentage of clay and silt.  Virus removal was shown to
increase with decreasing particle size.  The greatest percentage

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 of  removal took pla.ce In the uppermost portion of the  sand
 columns tested.  It was shown that for a well-sorted sand of
 particle  size averaging 0.12 mm, the removal efficiency in 2 ft
 of  penetration was 99.999 percent.

     Young and Burbank  ( 708) described studies of virus removal
 in  Hawaiian soils.  In  the laboratory, columns of various types
 of  Hawaiian soil were subjected intermittently to percolating
 water with a known concentration of virus (coliphage T4BZ mutant
 and polio virus Type II (Lansing) H8), simulating the action of
 cesspool  leaching.  The effluent from each soil column was
 analyzed  for viral content.  Coliphage T4 was applied to
 slightly  acid soils (pH 5-6) at a concentration of 2.5 x 106/m£.
 Percolation through 2.5 to 6 in of soil was 100 percent effec-
 tive in retention of the virus.    Slightly alkaline soil was
 less effective, removing only 67 percent of applied coliphage
 and 35 percent of applied polio virus in 15 in.  Removal of
 polio virus Type II was less complete; 6-in columns were able
 to  effect only 99.3 percent removal with an initial feed concen-
 tration of 1.5 x 10b. pfu/m£.

     Wellings et al.  (683 ) found that virus can be isolated at
 the 6.5 m level below a spray irrigation field.  Another study
 by  Wellings et al. (682 ) measured virus migration through the
 ground from chlorinated packaged plant effluent applied to a
 cypress dome.  Both horizontal  and vertical migration was
 detected  at distances of approximately 7 m for polio and
 coxsackie viruses.  Wells beyond that distance showed no virus.
 The survival of virus within the dome was at least 28 days.

     At Fort Devins,  Massachusetts, where a land application
 site has  been in operation for over 30 years, Schaub et al.
 (,565 ) studied the removal of bacteria from unchlorinated
 primary effluent applied to soil cells.  Using tracer f2 bac-
 teriophage and the enteroviruses poliovirus I, and EMC virus
 it was demonstrated that tracer bacteriophage penetrated into
 the groundwater along with the percolating wastewater.  The
 concentration in the groundwater stabilized at almost 50 percent
 of the applied virus  concentration.  The tracer and entero-
 viruses were sporadically detected at horizontal distances up
 to 600 ft from the application point.

     Lance et al.  (369) passed secondary sewage effluent con-
 taining 3 x 104 pfu/m£  polio virus Type I (LSc) through 250 cm-
 long columns packed with calcareous sand from an area in the
Salt River bed used for groundwater recharge of secondary sewage
effluent.   Viruses were not detected in l-m£ samples extracted
from columns below the  160-cm level, but were detected in 5 of
43 100-m£ samples  of  the column drainage water.  Most of the
viruses were adsorbed'in the top 5 cm of soil.  Virus removal
was not affected by the infiltration rate, which varied between


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15 and 55 cm/day.  Flooding a column continuously  for  27  days
did not saturate the top few centimeters  of  soil with  viruses
and did not seem to affect virus movement.   Flooding with
deionized water caused virus desorption from the soil  and
increased virus movement through the columns.  Drying  the
soil  for one day between applying the virus  and flooding with
deionized water greatly reduced desorption,  and drying for
five  days totally prevented desorption.  The investigators
concluded that large reductions (99.99 percent or  more) of
virus are expected after passage of secondary effluent through
250 cm or more of calcareous sand, unless heavy rains  fall with'
in one day after application of sewage.
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                            SECTION  8

                       FRESH SURFACE WATER
INTRODUCTION
     Approximately two-thirds of the water supplies  in  the  U.S.
are drawn from surface waters.   Direct discharge of  treated
wastewater to these fresh surface waters  is the most popular
method of wastewater disposal and the most significant  pathway
for wastewater contaminants to  reach potable water supply
systems.   In addition, relatively minor quantities of waste-
water contaminants may indirectly reach fresh surface waters
through runoff or percolation from land disposal of  wastewater
effluents.  This section of the report discusses current
knowledge about the fate of various effluent contaminants in
fresh-water systems.

     Most major river systems in the United States contain
wastewater effluent from upstream municipalities and industries.
the percentage of effluent wastewater volume varying from
negligible to over 10 percent.   Potable water systems utilizing
these rivers as a source supply are, of course, reusing waste-
water.  Therefore, there is intense interest in the  subject of
contaminant changes which may occur in the fresh water  system
between waste discharge points  and water intake locations.

     Much of the material contained in this chapter  was derived
from the following references:   162, 211, 239, 326,  534, 591,
and 624.

WATER QUALITY PARAMETERS

     General water quality parameters in surface waters are not
of direct public health concern, although they often degrade
the quality of the aquatic habitat.  For example, phosphorus
concentrations resulting from sewage disposal contributes to
luxuriant growths of certain algae, such an Anabaena, Nodularia,
or Nostoc - all of which produce toxins that can be  harmful to
humans (618, 680  ).  However,  the tastes and odor also asso-
ciated with such water degradation would generally make the
water unpotable long before the concentration of toxins reached
levels harmful to public health.
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     Suspended solids in wastewater can  carry  adsorbed viral and
other biological  contaminants (681).   Trace  metals occur  in
higher concentrations when associated  with suspended matter than
when they are in  a dissolved state (123), a  phenomenon that will
be discussed more fully in the following  section  on elemental
contaminants.  Suspended matter and dissolved organics from
wastewater can affect the natural biological community which,
in turn, affects the nitrogen interconversions and nitrate con-
centrations.

     The nitrogen-containing compounds (ammonia, nitrite, and
nitrate) are theoretically hazardous because of nitrate's
association with methemoglobinemia.  Ammonia and nitrite nitrogen
can be readily converted into nitrate by chemical or biological
reactions.   There are, however, no reported  cases of detrimental
public health effects resulting from nitrates in surface waters.
This is because the dilution and natural processes occurring in
surface waters prevent nitrate concentrations from reaching
health impairing levels.  There are, however, several  reported
cases of groundwater nitrate contamination rising to dangerous
levels.  These cases are discussed in the 1 and/groundwater
section of this report.

ELEMENTAL CONTAMINANTS

     The behavior of elemental contaminants  in fresh-water
systems is very complex.  Generally, elemental  contaminant
transport mechanisms can be divided into either elements  in
solution or elements associated with inorganic or biological
particulates.  Each of these mechanisms  can  be broken  down
still further.  Dissolved elements may occur as unassociated
ions or as inorganic or organic complexes.   Elementals/inorganic
particulate associations include coulombic attraction, as in
conventional adsorption; ionic bonding,  as in  ion exchange;
precipitated or coprecipitated metal coating;  or incorporation
into particulate  crystalline lattices.   Elementals/biological
particulate associations  include  surface adsorption,  ingested
particulation, and  biochemical  Incorporation  into the organism.
The particular transport mechanism  that will  predominate in a
given water system  depends,  in  part, on the geohydrologic
environment, mineralogy/petrology  of the river  or lake bed, pH,
temperature, dissolved  organic  or  oxygen content, biological
activity, elemental  type and  source, and nonelemental chemical
composition of the  water.

     This variety of factors  does much to explain the seeming
discrepancies in the work of  different researchers attempting
to establish element    distributions in fresh-water systems.
For instance, Gibbs  (246),  in his examination  of the Yukon and
Amazon Rivers, concluded that precipitated metal coating and
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crystalline incorporation  accounted for approximately 90 percent
of the transported  iron, nickel, copper, chromium, cobalt,  and
manganese (Table  53).   Perhac  (512), on the other hand, in  his
analysis of two Tennessee  streams, concluded that 95 percent
of the total  stream content  of cadmium, cobalt, copper, nickel,
lead,  and zinc was  in  the  dissolved state (Table 54).  Assuming
that there was no gross experimental error, widely differing
environmental  factors  must have prevailed.

     The complexity of the chemistry, biology, and physics
involved in water behavior of  elements precludes a detailed dis-
cussion.  Instead,  a brief discussion  is  presented  of the  more
important aspects of the  behavior of elements in water,
followed by a detailed examination of  a  few sample  elements
(mercury, arsenic,  lead,  cadmium,  copper,  iron)  to  demonstrate
the principles involved.

     Dissolved elements   may occur as unassociated ions or as
inorganic or organic complexes.   Of the  major elements under
discussion in this  report, only barium appears to any great
extent as the unassociated cation; barium ions do not hydrolyze
and form only weak  complexes.   However,  several  of  the elements
occur as unassociated anions:   antimony,  arsenic, boron, chromium,
molybdenum, and  selenium  generally occur  in fresh-water systems
as the oxo anion.  This is largely because the major sources of
these elements,  including  wastewater,  are rich in the anionic
forms, and because  the cationic forms  are easily oxidized  to the
oxo anion in aquatic systems.

     The majority of the  dissolved elements   normally exist as
inorganic or organic complexes.   Table 55  lists the more  common
ligands and the  conditions and elements    normally  associated
with them.  In relatively  pure water,  aquo (1^0) or hydroxo
(OH")  complexes  are formed.   At pH levels above neutral, many of
the metal-hydroxo complexes  are converted to metal  hydroxides or
oxides, which will  precipitate out of  solution or behave as
colloids.

     The other inorganic  ligands responsible for keeping metals
in solution in natural waters include  carbonate, halides
(notably chloride and fluoride), sulfur  species (SH-* sulfate,
and sulfite), and nitrogen species (ammonia, nitrate, and
nitrite).  Most  of  the complexes formed  from these  ligands are
thermodynamically unstable and appear  as  transition states
between the free  metal ion and a precipitate.  The  complexes,
however, serve to keep the metals in solution for a time,  and
play a role in dissolving  otherwise insoluble metals from
precipitates or  crystalline  lattices.

     Of somewhat  more importance in terms of complex stability
are the multidentate organic ligands.   One of the reasons  for


                              121

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       TABLE   53.  PERCENTAGES OF THE TOTAL  AMOUNTS  OF
    IRON,  NICKEL,  COBALT, CHROMIUM, COPPER,  AND  MANGANESE
             TRANSPORTED BY FIVE MECHANISMS  IN  THE
                 YUKON AND AMAZON RIVERS  (246)
Mechanism
In solution and
organic complexes
Adsorbed
Precipitated and
copreci pita ted
In organic solids
In crystalline
sediments

In solution and
organic complexes
Adsorbed
Precipitated and
copreci pi tated
In organic solids
Iron Nickel
Amazon River
0.7 2.7
0.02 2.7
47.2 44.1
6.5 12.7
45.5 37.7
Yukon River
0.05 2.2
0.01 3.1
40.6 47.8
11.0 16.0
Cobalt Chromium
1.6 10.4
8.0 3.5
27.3 2.9
19.3 7.6
43.9 75.6

1.7 12.6
4.7 2.3
29.2 7.2
12.9 13.2
Copper Manganese
6.9 17.3
4.9 0.7
8.1 50
5.8 4.7
74.3 27.2

3.3 10.1
2.3 0.5
3.8 45.7
3.3 6.6
In crystalline
 sediments           48.2   31.0    51.4    64.5    87.3     37.1
                            122

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                                  TABLE  54 .  HEAVY METAL DISTRIBUTION
                                             IN STREAMS  (512)
CO
Percentage of element occurring in dissolved and
solids
Cadmium
Cobalt
Copper
Iron
Manganese
Nickel
Dissolved solid
Coarse parti cul ate
Colloid
Dissolved solid
Coarse participate
Colloid
Dissolved solid
Coarse parti cul ate
Colloid
Dissolved solid
Coarse parti cul ate
Colloid
Dissolved solid
Coarse particulate
Colloid
Dissolved solid
Coarse particulate
Colloid
Sample 1
95.4
3.9
0.8
95.9
3.9
0.2
95.0
3.6
1.4
18.8
79.5
1.7
23.2
76.4
'0.4
96.5
3.4
0,2
Sample 2
95.3
4.2
0.5
93.2
6.2
0.6
94.4
3.8
1.8
12.5
86.0
1.4
41.7
57.6
0.7
95.2
4.5
0.3
particulate
Sample 3
95.8
3.5
0.7
95.9
3.5
0.7
90.4
8.2
1.4
26.9
67.1
6.0
18.5
74.8
6.7
96.6
2.4
1.0

Sample 4
85.1
8.9
6.0
82.3
17.5
0.2
93.0
5.8
1.2
20.4
75.5
4.1
10.4
89.5
0.1
84.7
14.8
0..5

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     TABLE  54 (continued)
Percentage of element occurring 1n
solids

Lead
Zinc

Dissolved solid
Coarse particulate
Colloid
Dissolved solid
Coarse particulate
Colloid
Sample 1
95.0
5.0
Tr
85.0
15.0
Tr
dissolved and particulate
Sample 2
90.9
7.6
1,6
53,3
46.2
0.5
Sample 3
87.9
9.3
2.9
91,9
7.3
0.9
Sample 4
89.5
10,1
0.4
81.1
18.5
0.4
ro

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                    TABLE  55.   METALS COORDINATED BY LI6ANDS NORMALLY
                             FOUND IN NATURAL HATERS (521 )
ro
en
Metal
Carried
Boron
Aluminum
Barium
Chromium
Copper
Cobalt
Molybdenum
Manganese
Iron
Nickel
Z1nc
Cadmium
Mercury
Lead
Arsenic
Antimony
Ugands Responsible
0~* S"2 , , ?
H20 or OH" or SH" S04"Z S03'Z F~ Cl" C03~* Organic NH3 NHgOH N02
26 1461 6
5 P p(c)
2 64 6 c) 6 6
3 6 4(b) 6(c) 6 (e) 6
46 4 6(c) 6 6
16 6 v
3 4 6 c 6
3 6 614 6 c 6(d)
3 ? 4 6 c 6 (e)
3 6 6 4 6 c) 6 (e)
4 46 616
4(a) 6 6 1 6
2 P 4 6(c) 6
1 6 4
1 6 4
Footnotes
1 In normal natural waters (pH 0-11) this metal Is coordinated by this llgand.
2 Here coordination occurs only at pH of less than about }• . .
3 Normally coordination only occurs at a pH of ess than 4, but If the pCO, Is low
(high concentration), then bicarbonate which 1s water coordinated will bfe formed.
4 Coordination occurs at a pH of 7 or less.

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5   The solubility falls markedly in the presence of this
    ligand at above pH due to precipitation of a carbonate
    or similar basic compound.
6   Coordination  occurs only at pH above 7 due to ligand
    instability,  etc.                                3
7   Coordination  occurs only at pH above 8-9.
P   Precipitation almost always occurs.
    (a) Water will  only coordinate if no other stronger
        ligand is present.   In  some  cases,  there is an
        equilibrium.
    (b) Bromide and iodide resemble  chloride except that
        they both precipitate silver,  whereas  silver
        chloride  is fairly soluble due to  AgClz'ions at
        high chloride  concentrations.   Iodide  also  pre-
        cipitates copper and gold.
    (c) Bicarbonate usually forms  carbonato complexes,  but
        metals so marked have a soluble  bicarbonate which
        is water  coordinated.  Be  and Tl  have  soluble water
        coordinated carbonates, and  Ag has  both sparingly
        soluble water  coordinated  carbonate and hydroxide.
        Two valent iron in absence of air  only.
        If ammonia is  absent, a complex  may be formed.

    If nothing is marked, there is no coordination  of this
    metal  by this ligand in natural  waters.
(d)
(e)

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the lack of inorganic  complex stability is that most of the
inorganic ligands  are  monodentate, i.e., there is one ligand for
each metal ion coordination site.  Organic ligands are multi-
dentate, i.e., a given ligand can usually bond to two or more
of a given ion's coordination sites.  A multidentate complex
(chelate) is more stable than a corresponding complex with
monodentate ligands; thus, a chelate complex is apt to keep a
metal ion in solution far longer than will an inorganic complex.
Normally, this is not a problem; in relatively unpolluted fresh
water the organic content is low, but in highly polluted water
unusually high soluble metal concentrations  may result.   Further-
more, there is evidence that some synthetic  organic ligands,
such as may be found in wastewater,  form stronger complexes than
do natural organic ligands (384).  It has been demonstrated that
one synthetic ligand, nitrilotriacetate (a proposed substitute
for phosphates in detergents),  is capable of dissolving signifi-
cant quantities of precipitated lead out of  bottom sediments
(268, 715 ).

     The tendency for a given metal  ion and  ligand to form
complexes depends on solution pH, concentration of the metal
and ligand, concentrations of other metals and ligands in
solution, equilibrium constants, redox conditions, and so forth.
No two elemental contaminants behave exactly alike, and even
different oxidation states of the same element   may exhibit
widely varying solution chemistry.   Moreover, natural water
systems are seldom in an ;equilibrium condition before, much less
after, wastewater addition.  This constantly changing system
makes concise pathways almost impossible to  construct.  In
general, low pH, an oxidizing environment, and the presence of
a variety of ligands enhance element   solution tendencies.
This is significant from a public health standpoint, because
soluble elemental species are much more readily available for
human contact than are precipitates or particulate elementals.

     Elemental/inorganic  particulate  interactions  typically
account for the bulk of the nondissolved elemental fraction.
These interactions include coulombic or ionic attraction,
precipitated or coprecipitated coating, or lattice incorporation.
Coulombic attraction, or adsorption, is the  least important
transport mechanism except in the case of colloidal particulates,
such as microparticulate iron or manganese hydroxides, which
carry a weak negative charge and attract elemental cations.
Larger particulates do not possess a strong  enough charge to
make coulombic attraction important.

     Ionic attraction, or ion exchange, is somewhat more
important.  In this process, the heavy metal elements   (Mn,
Fe, Co, Ni, Cu, Zn, Mo, Cd, etc.) replace alkali and alkali
earth cations (K, Na, Li, Mg, Ca) attached to crystalline
lattices by ionic bonds.  These  ionic bonds  will hold unless
(1) the element   is displaced by another element   forming a

                               127

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 stronger ionic  bond,  (2)  a  ligand  forming  a  coordination  bond
 stronger than the ionic bond breaks  the  ionic  bond,  or  (3)  an
 excess  of alkali  or alkali  earth  cations  is  available  to  force
 the equilibrium back  to its original  state.

      According  to Gibbs (246),  lattice incorporation  is generally
 insignificant as  a transport or removal mechanism  of  dissolved
 wastewater elements.     It  is  a slow  process that  takes place
 in  the  sediments  and  has  a  more significant  impact on  the
 elemental  composition  of  the sediments.  The lattice-incorporated
 element  burden  of  a water system is primarily from  weathered
 rock, sand, and clay.

      Precipitated  and  coprecipitated metal coatings account for
 most  of  the non-native  particulate element   content of a  water
 system.   Under  favorable  pH-EH  conditions, metal precipitates
 will  form.  The initially small precipitate particles will tend
 to  agglomerate  or  adhere  to  any available surface.   In addition,
 cations  held  to particulates by coulombic or ionic bonds can
 form  covalent bonds with  anionic components of the particulate,
 if  solution redox  potentials change.   In either case, the
 particulates  are  left  with  a coating of metal precipitates.
 This  coating  ultimately settles out of solution with the partic-
 ulate, removing the elements    from possible ready human
 contact  unless  they are redissolved by a change in redox
 conditions, a strong ligand, or some other agent strong enough
 to  attach  the precipitate.   These coatings may account for the
 bulk  of  the inorganic  particulate element   burden of waste-
 waters.

      Elemental  contaminants  incorporated with biological particu-
 lates constitute  the remainder  of the particulate elemental
 burden of  a water  body  or wastewater.  This incorporation  may
 take  the form of  surface adsorption,  inorganic  particulate
 ingestion, or biochemical incorporation into an organism's
 tissues.   Obviously, the role played by biological  transport is
 highly dependent  on the type and quantity of organisms present.
 Surface  adsorption is  usually associated with microorganisms.
 Particulate ingestion  is associated with those  organisms that
 have  internal digestive organs  (e.g., fish, crustaceans, worms,
 etc.); ingested particulates are usually eliminated within a
 short time, but the elements    associated with  them may be
 biochemically incorporated  into the organism's  tissues.   From a
 public health standpoint, soluble and biochemically incorporated
 elementals are the most important, for it is by these routes
 that potentially hazardous elements   reach man.  Biochemical
 incorporation involves both  essential trace element concentra-
 tion  (e.g., cobalt in vitamin B-12) and reaction of an element
with cellular chemicals (e.g.,  the reaction of  mercury with
 sulfur-containing  amino acids in proteins).  Both plants and
 animals  are involved and,  thus,  the concentration of a given
 element  may move up the food chain.   The incorporation is

                              128

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reversible;  once  the  organism  is removed from contact with the
element,  the latter can  gradually  be excreted.

     No two  elements  behave  exactly alike; furthermore, the
number of factors available  that can affect transport mechanisms
makes the possibilities  nearly endless.  There are similarities,
however,  that make the  use of  examples  illustrative and useful;
mercury,  arsenic, iron,  cadmium, copper, and  lead will be used
to provide detailed descriptions of the  general  pathways dis-
cussed above.

     Mercury from wastewater enters a water system primarily as
the metal or divalent cation.   Although of limited solubility,
it can reach concentrations of 100 ppb in aerated water (234;.
Metallic mercury alone  is soluble up to 25 ppb and will hydrolize
to soluble  Hg (OH)2  in  oxygenated systems, increasing the overall
solubility  and water content.   Despite these solubility figures,
mercury  concentrations  seldom  exceed 5 ppb (Table  56 )  except
in polluted  water.

      Inorganic and biological  adsorption, absorption, and pre-
cipitation  serve to  keep the  concentrations  of  dissolved mercury
much  lower  than  the  theoretical maximum.  In general, the bulk
of the mercury in a  given water system is  in  the sediments;
Table  57  gives a summary of some of the mercury concentrations
in the sediments  of  Lake Erie.  In reducing sediments,  mercury
is tied  up  as the sulfide,  although if the system becomes
sufficiently alkaline,  HgS?"  may  be  released into  solution.
Should the  sediments become aerobic,  the  sulfide  will  be  oxidized
to sulfate, and  the  mercury will  be  released.

      All soluble mercury species  except mercuric  sulfide can be
absorbed by bacteria.   Once the  mercury is  in  the bacteria, a
 series of transformations  - possibly via  a  detoxification
mechanism - convert  the incorporated mercury into mono-  and
 dimethyl mercury, both soluble at low concentrations and readily
 released into solution.  The  methyl  mercury  compounds are much
 more 1ipid-preferring than the inorganic  forms and are quickly
 absorbed by living tissues.  As a rule, mercury concentrations
 tend to increase in  organisms up the food chain,  so that the
 highest concentrations are found in fish.  This is partly due to
 absorption of methyl mercury  from the water and partly from
 inqestion of plants  or smaller organisms containing methyl
 mercury.  When  the  organisms  die, the mercury returns to the
 sediments, where most  of the  bacterial methylation occurs.
 Table 57   lists  some sample  sediment and plankton/algae mercury
 concentrations  in Lake Erie.

      Arsenic, selenium, and  antimony are chemically similar  and
 exhibit  analogous environmental  behavior.   Arsenic  has  been
 studied  far more than  either selenium  or antimony.  The  following


                               129

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             TABLE  56.  SELECTED CONCENTRATIONS OF
                 MERCURY IN NATURAL WATERS (234)
Source and Location
                                                 Mercury (ppb)
River water, European USSR
River water, Armenia
Saale River, Germany
River water, Italy
River water, near mercury deposits, Italy
Colorado River, Arizona
Ohio River, Illinois
Mississippi River, Kentucky
Missouri River, Montana
Missouri River, St. Louis, Missouri
Kansas River,  Topeka, Kansas
Hudson River,  New York
Lake Champlain, New York
Maumee River,  Antwerp, Ohio
Delaware River, New York
                                                    0.4-2.8
                                                      1-3
                                                  0.035-0.145
                                                   0.01-0.05
                                                   up to 136
                                                     <0.1
                                                      0.1
                                                      2.8
                                                      3.5
                                                      0.1
                                                      0.1
                                                      6.0
                             130

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  TABLE  57.  MERCURY CONTENT OF SEDIMENTS  AND  PLANKTON/ALGAE SAMPLES
                    COLLECTED FROM LAKE ERIE   (519)
Mercury content in vg/ga
Station
No.
01
02
03
04
05
06
07
08
09
10
11
12
13
14
15
16
Approximate
Location
Buffalo River
Cattaraugus Creek
Barcelona
Ashtabula
Fairport
Cleveland
Toledo
Detroit River
Mid. Bass Island
Port Crewe
Port Stanley
Long Point
Long Point Bay
Port Maitland
Mid-Lake
Black Rock Channel
ij 	 *>• "- - . -•l"!J|_-' __•_ 	 '-!__ '"!_ ••I 1" I"" i " '-'-'.' ^
Sediments
2.0
1.2
0.6
4.6
1.5
12.0
10.4
4.5
1.5
0.5
1.5
7.0
1.0
1.8
1.5
12.4
..••I _!!• ••_! I_M _!•>-••••
Plankton/Algae
31.2
25.1
2.8
7.4
12.8
33.5
20.5
26 .1
20.1
12.4
12.0
14.7
23.7
15.4
0.6
27.8
±aaam^aamam
a  In terms of the equivalentdry wt of  the  sample.

b  Sediment samples from 3 to  30 cm below the water-sediment interface.
                                  131

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discussion of arsenic is largely applicable to  selenium and
antimony as well.

     Arsenic has an unusually complex chemistry in  aquatic
systems:  oxidation-reduction, ligand exchange, precipitation,
adsorption, and biomethylation reactions  all  take  place.
Arsenic species can be removed from water via surface  adsorption
                                                        "^
and coprecipi tation with metal ions; both arsenate (AsO^") and
arsenite (As03~3) have a high affinity for hydrous iron oxides
and readily coprecipitate with or adsorb onto them.  Signifi-
cantly, iron ores are always enriched with arsenic (214).
Aluminum hydroxide and clays are adsorb arsenate species,
although to a lesser degree.

     Microbial  transformations of arsenic,  while demonstrable
in the laboratory, have not been  positively identified  in
natural water systems.   The two most commonly postulated trans-
formations  are  oxidation of arsenite and methylation.   Methyla-
tion is important because it could be a means by which  sediment
arsenic is  recycled  back into the water system;  natural  aquatic
methylation has  not  been demonstrated.

     Soluble iron entering  a water system in  wastewater will
usually be  either ferrous (Fe II) or complexed ferric  (Fe  III)
iron.   The  former is much more soluble than the  latter  (which
has a  stronger  tendency to  form complexes),  although  neither
tends  to remain  in solution long.  In the surface layers of
most natural waters, pH levels and oxygen conditions  are such
that Fe (II) is  readily oxidized  to Fe (III), which just as
readily hydrolyzes to insoluble hydrous ferric oxide  (FeOOH).
Hydroxide  has a  much stronger affinity for ferric iron  than do
basic  organic or inorganic  ligands.

     Hydrous ferric  oxide tends to form microcrystal 1 ine preci-
pitates of  a colloidal  nature, so that it is  almost impossible
to analytically  distinguish between soluble and  colloidal  iron.
Consequently, the two forms of iron are usually  reported together
as soluble  iron.  Although  hydroxide supersedes  other  anionic
ligands,  frequent incorporation of coordinating  anions  into
ferric oxide precipitates enhances colloidal  stability  and
further blurs the distinction between the colloid and  soluble
ferric complexes.

     Cadmium readily precipitates as the hydroxide or  carbonate
and consequently is  not normally  found in high concentrations
in surface  waters.  In  fact, several researchers (188,  461 ) have
noted  that  high  soluble cadmium concentrations are invariably
associated  with  polluted water that receives  a steady  cadmium
source, such as  industrial  wastewater.
                              132

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     Cadmium (II) readily hydrolyzes and forms  transitory
inorganic complexes,  such as chloride complexes  that have a
limited affinity for  hydrous iron and manganese  oxides,  and
organic particulates.   The organic affinity probably indicates
a reaction between the cadmium and sulfur-containing compounds.

     Cadmium forms the insoluble hydroxide at pH levels  of 7
and above; it forms the insoluble carbonate under oxidizing
conditions, particularly in soft waters where cadmium does no.t
have to compete with  calcium and magnesium for  the carbonate
anion.   Once cadmium  has precipitated and settled into the
sediments, it is not  readily removed.  Consequently, if  cadmium
additions are reduced, a water body will tend to purify  itself
of soluble cadmium.

     Copper, and to a  lesser extent nickel, occupy an unusual
position in water chemistry and biology because  they are both
nutrients and toxins.   This has a pronounced effect on their
water chemistry.  Copper contained in wastewater may be  either
soluble or particulate; neither form predominates as a rule.
Copper adsorbs readily onto clay and organic particulates.
Copper also forms several very stable complexes.  In pure water,
while the aquo complex may predominate, the carbonate, chloride,
and amine inorganic complexes are much more stable.

     Ultimately, the  soluble stability of copper can be
attributed to organic  complexes, since copper forms coordination
complexes with virtually every conceivable organic ligand.
These complexes are very stable thermodynamically and are also
resistant to microbial attack, a mechanism responsible for the
destruction of most organic complexes.  Copper is a bacterial
toxin and, if released from its complex by microbial attack,
simply kills the offending bacteria and forms a new complex (461)

     Copper is removed from solution via precipitation or
biological incorporation.  Since the most common precipitate is
the carbonate, most sediment copper is in the carbonate form
(140, 461).  An essential trace nutrient, copper is readily
incorporated into aquatic plants and animals.

     The main soluble species of lead  in wastewater are the
lead (II) cation and  the hydrolyzed complex Pb  (OH)3~.  Lead
forms a variety of stable complexes as well; researchers  (381)
have identified both PbOH+ and  Pb(C03)2"^  in natural water
systems.  Lead complexes easily with a variety of organic
chelates, forming very stable complexes.   Some of these com-
plexes are more stable than the sediment lead precipitates;
therefore, they will  actually dissolve otherwise  insoluble lead.
A case in point is nitrilotriacetate,  which can  solubilize lead
from lead carbonate precipitates  (268).
                              133

-------
      Low water organic content generally prevents  solution  lead
 concentrations from exceeding a few parts per billion.   In  most
 water systems, lead introduced with wastewater  readily forms
 insoluble Pb(OH)2 and PbC03, which will precipitate and  adsorb
 onto suspended particulates.  Ionic lead is not so strongly
 adsorbed, although it does have some affinity for  clays.

      Hydrous iron oxides strongly sorb ionic lead  at neutral
 to slightly acidic pH levels.  Some ionic or complexed lead
 adsorbs onto or is chelated with the surface mucilage of algae,
 and microorganisms immobilize substantial  quantities of  inorganic
 lead, presumably on or in all membranes (648 ).   As a result of
 all of  these mechanisms,  most of the water lead  burden is
 associated  with  particulate  matter, and most of  the lead  entering
 a  normal  water  system  ultimately finds  its way into the sediment!

      Natural  water  bodies normally contain very  low dissolved
 concentrations  of  the  more harmful elemental contaminants.
 Unless  wastewater  additions  are voluminous and repeated,  natural
 water chemistry can purify the water of soluble  species fairly
 well.   However, there  is  a buildup of these elements in the
 sediments.   This means that  if the local water chemistry  should
 change  significantly,  the elements can still be  released  to
 solution.   Natural water  purification mechanisms can only change
 the wastewater element problem from a real to a  potential
 hazard; they  cannot solve the problem of element contamination.

 BIOCIDAL  CONTAMINANTS

      In general, municipal wastewater will  have detectable
 quantities of biocides only if it contains biocide manufacturing
 wastes.    The  single most  important source of biocidal  contami-
 nants in  fresh-water bodies is surface runoff,  followed by aerial
 fallout and industrial waste discharge from plants manufacturing
 biocides.   Cleanup and disposal by households,  farmers, gardeners,
 etc., contribute minimally to the overall  wastewater burden.

      In  this discussion, biocides will  be classed as chlorinated
 hydrocarbons, organophosphates, carbamates,  and ionic  biocides
 (Table 58).

     Biocides can be transported  or removed  from  the system  by
microbial  or chemical  degradation,  photodegradation, adsorption
to sediment or humic matter,  adsorption,  volatilization,  and
biological uptake.   All of these  mechanisms  are in  turn affected
by pH, temperature, salt or organic content,  and  bioproductivity
One mechanism that has not been studied  to  any  great degree  -
especially in fresh water - is aerosolization.    This mechanism
will be  discussed in greater detail in the marine water section
of this  chapter, as its importance in fresh-water systems is
limited  mainly to the  larger lakes.  Briefly, however, aerosoli-
zation occurs through  the action of wind and waves  on floatables.

                               134

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             TABLE   58.   BIOCIDE  TYPES  AND  EXAMPLES
Chlorinated Hydrocarbons

    DDT (ODD, DDE)
    Methoxychlor
    E n d r i n
    D i e 1 d r i n
    Aldri n
    Toxaphene
    Lindane
    Chlordane
    Heptachlor
Organophosphates

Parathion
Malathion
Dimethoate
Methyl parathion
Phorate
Demeton
Ethion
Disulfaton
    Carbamates

    Carbaryl
    Sevin
    Baygon
    Pyrolan
    Dimetilan
Ionic Biocides

 Diquat
 Paraquat
 Chlormequat
 Morfaunquat
 Phosphon
 Hyamine
 2,4-D
 2,4,5-T
 Dalapon
 Si 1 vex
 Dichlobenil
                               135

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 Aerosols  and  particulates  can  be  released to the air and trans-
 ported  great  distances  by  the  wind; biocides can concentrate in
 floatables  via  dissolution  in  surface oil, adsorption on floating
 matter,  or  flotation  (caused by low specific gravity and insolu-
 bility),  thus  becoming  amenable to the aerosolization process.
 As  mentioned  above, this is not an important transport mechanism
 in  most  fresh-water systems.

      Various  transport  mechanisms affect the biocide classes
 differently.   This  is demonstrated in Table 59, which compares
 the persistence  of  selected chlorinated hydrocarbons, organo-
 phosphates, and  carbamates  in  river water.  Because of these
 differences,  the  biocide classes will be discussed separately.

      The  chlorinated  hydrocarbon  pesticides are all  insoluble
 in  water, with  the  exception of lindane,  which  is  sparingly
 soluble  to  10  ppm (211).   They are generally  resistant  to
 microbial and  chemical  degradation, as evidenced  by  their
 estimated environmental half-lives, shown in  Table   60.


        TABLE  60.  ESTIMATED  PESTICIDE HALF-LIVES  (211)

      Pesticide	Half-Life, yrs	

      Lindane                      2
      Chlordane                    8
      Toxaphene                    11
      Heptachlor                   2 to 4
      DDT                          10 to 20
      Endrin (Dieldrin)            8 to 10


      These pesticides are  somewhat more susceptible  to  photo-
 degradation, although the  degradation products are often as
 toxic as the parent compound,  regardless of the type of
 degradation.  DDT is decomposed chemically to ODD and DDE and
 photochemically to PCB's (162, 550 ); aldrin is photooxidized
 to  the more toxic dieldrin  (162); and methoxychlor is degraded
 to methoxychlor DDE (501 ).  Surface oil slicks tend to concen-
 trate chlorinated hydrocarbons and thus make them more  available
for photochemical degradation  (162).

     Chlorinated  hydrocarbons  in general readily adsorb onto
fungi, algae,  and floe-forming bacteria (385,  501  ), and thus
tend to concentrate in  biological communities.  When ingested
by higher organisms, they accumulate in lipid  tissues;  conse-
quently, there is a tendency for chlorinated hydrocarbons to
concentrate up the food chain.

     Chlorinated  hydrocarbon insecticides differ in chemical
structure, but they all  exhibit affinity for organic sediments

                               136

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          TABLE  59.  PERSISTENCE OF COMPOUNDS IN  RIVER WATER (415)
                          Original compound found,  percent	
Compound	0-time     1 wk     2 wk     4 wk     8 wk

Organochlorine compounds

  BHC                     100      TOO      100      100     100
  Heptachlor              100       25        0       0       0
  Adlrin                  100      100       80      40      20
  Heptachlor epoxide      100      100      100      100     100
  Telodrin                100       25       10       0       0
  Endosulfan              100       30        5       0       0
  Dieldrin                100      100      100      100     100
  DDE                     100      100      100      100     100
  DDT                     100      100      100      100     100
  ODD                     100      100      100      100     100
  Chlordane (tech.)       100       90       85       85      85
  Endrin                  100      100      100      100     100

Organophosphorus compounds

  Parathion               100       50       30       <5        0
  Methyl parathion          80       25       10        0        0
  Malathion               100       25       10        0        0
  Ethion                  100       90       75       50       50
  Trithion                  90       25       10        0        0
  Fenthion                100       50       10        0        0
  Dimethoate              100       100       85       75       50
  Merphos                    00000
  Merphos recov. as Def   100       50       30       10       <5
  Azodrin                 100       100       100      100      100

Carbamate compounds

  Sevin                     90         5         0        0        0
  Zectran                  100       15         0        0        0
  Matacil                  100       60       10        0        0
  Mesurol                   90         0         0        0        0
  Baygon                   100       50       30       10        5
  Monuron                   80       40       30       20        0
  Fenuron                   80       60       20        0        0
                                 137

-------
and resistance to microbial attack.  As a result, there is
accumulation in bottom sediment.  Research on Lake Michigan
demonstrates this, as shown in Table  61.  Routh ( 558) showed
that DDT, with its affinity for fine participate clay sediments,
concentrated up to 20 times normal background levels, from 10
to 200 ppb.  This affinity for organic matter and particulates
leads to high sediment DDT concentrations.  Table 62   shows DDT
concentrations in stream sediments over a period of time.
Adsorption of DDT on algae can be 10 to 100 times greater than
adsorption on clay (350).  Moreover, DDT seems to have an
inhibitory effect on sediment bacteria (11).

     There has been little research on other chlorinated hydro-
carbons, much of it limited to an evaluation of environmental
levels.  Table 63  gives the results of one such survey for
d i e 1 d r i n .


        TABLE  63.  DIELDRIN IN RIVER BOTTOM SILTS (466)

     Source	D i e 1 d r i n (ppb)

     Iowa River                                  8.8
     Des Moines River                           35
     East Nishnabotna River                     21
     West Nishnabotna River                     16
     Upper Iowa River                           <1
     Johnson County Creek                      170


     Other researchers have found that the highest reported
concentrations of several pesticides in major U.S. river basins
from 1958 to 1965 were as follows:  dieldrin, 0.100 yg/£;  endrin,
0.116 yg/£; and DDT, 0.148 yg/£.  Dieldrin was the most widely
found pesticide (679 ).

     The organophosphorus biocides are more soluble than the
chlorinated hydrocarbons.  These solubilities range from 1 ppm
for ethion to 20,000 ppm for dimethoate; most fall in the 25 to
150 ppm range (211).  The organophosphorus biocides are also
more amenable to both microbial and chemical  degradation.   Even
parathion, the most chemically resistant of the organophosphates,
will degrade via ester linkage hydrolysis in a few months  under
normal  conditions.  The degradation takes place in just a  few
weeks in polluted water with a high bacteria count (264).   Yu
and Sanborn's (709 ) experimental evaluation of parathion  in a
model ecosystem yielded a calculated half-life of 15 to 16 days.
In a similar study, guthion yielded a half-life of one month at
pH levels less than 9 and a half-life of less than one week at
more alkali ne pH's.
                               138

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CO
                                   TABLE 61 .   CHLORINATED  HYDROCARBON  INSECTICIDES
                                      IN SOUTHERN  LAKE  MICHIGAN SEDIMENTS  (yg/1)  (382)


Insecticide
p,p'-DDT
o,p-DDT
p,p'-DDE
o,p-DDE
p,p'-DDD
o,p-DDD
Total DDT
complex
Dieldrin
Heptachlor
epoxide
Lindane

Mpdian
9.3
1.2
2.2
Tr
3.0
Tr
18.5

2.0
Tr

Tr
interval
50%
Mid-range
5.5-17
Tr-2.0
0.6-3.5
Tr
1.4-10
Tr-1.8
10-32

1.3-4.1
Tr-0.7

Tr

No. of
Samples
59
54
59
49
54
49
59

54
54

45
— i ••
Median
3.8
0.7
0.8
ND
0.5
ND
6.3

Tr
Tr

ND
2-6 cm
50%
Mid-range
2.6-5.2
Tr-1.0
Tr-1.5
ND
Tr-2.0
ND-0.5
3.9-13

Tr-1.1
ND-0.5

ND-Tr
No. of
Samples
40
37
40
32
37
32
40

37
32

30

Median
3.0
Tr
0.6
ND
ND
ND
3.4

Tr
ND

ND
6-12 cm
~~%Q%
Mid-range
1.5-6.0
ND-2.3
Tr-2.1
ND-Tr
ND
ND
2.2-8.1

Tr-0.9
ND

ND
No. of
Samples
20
14
19
12
12
12
20

14
14



-------
     TABLE  62.  DDT CONCENTRATIONS IN STREAM SEDIMENTS (271)
 Years after                     DDT
     one                        (ppro)
 application	
      0                         .83
                             (.04-1.6)

      1                        1 .08
                             (.25-1.9)

      2

      3                         .21
                             (.12-.30)

      4                         .21
                             (.16-.25)

      5                         .59
                             (.07-1.9)

      6                         .06
      7                         .21
                             (.11-.31)

      8                         .13
      9                         .03
                             (.02-.04)

     10                         .07
                             (0-.16)

Never sprayed                   .006
                             (0-.02)

Two sprays                      .43
                             (.17-.77)

Three sprays                    .35
                             (.17-.6)
                         140

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     Interestingly,  the degradation  of  organophosphates  can  be
inhibited by the presence of other synthetic  organic  chemicals.
Experiments were conducted with two  detergent surfactants  -
alkyl  benzene sulfonate (ABS) and linear alkyl  benzene  sulfonate
(LAS).   These experiments demonstrated  increased  persistence
for several organophosphate insecticides,  especially  parathion
and diazinon (162).   As a result, highly polluted water may
exhibit accumulations or half-lives  far beyond the normal  for
organophosphates, which, as a rule,  neither persist nor accumu-
late in the environment, but are removed entirely within a few
months.

     Carbamate biocides are moderately soluble, ranging from 7
ppm for terbutol to 250ppm for propham and averaging  around  100
ppm (211).  In general, they decompose easily and show little
tendency toward adsorption on suspended material, but hydrolyze
readily.   The hydrolysis is particularly pH dependent,  virtually
ceasing entirely below pH 5  (211) and increasing as the pH and
temperature rise.  High salt content affects the hydrolysis
rate inversely, slowing the  rate as the salt concentration
increases  (211).  Carbamates photodecompose  readily - increasingly
so, as  the  pH rises -  and can be rapidly biodegraded under
normal  circumstances  (550 }.  Carbamates are not, then, persistent
in  normal  water systems,  lasting only a few  days to a few weeks,
but remain  as a stable compound  in  acidic waters  (211).

     Ionic  biocides are a broad  class embracing  a variety of
chemical  types  and uses.  They are  all  considered soluble in
water,  with solubilities  ranging  from 100  to more than  1,000,000
ppm.   Ionic biocides  that are marginally soluble  in pure  water
have increased  solubilities  in natural  waters  high in  humic
acid salts (211).  With  few  exceptions, these  biocides  do not
accumulate or persist and,  consequently, are seldom found in
high concentrations.

      Ionic biocides  are,  however, strongly adsorbed onto  soil
particles, all  types  of  clay,  humic matter,  and  organisms -  in
short,  onto anything  with a  partial charge or  an ion exchange
capability (211).  They  are  generally  resistant  to chemical
attack but photodegrade  readily, except when adsorbed  onto
particulate matter  (211).   Ionic biocides  respond  differently to
microbial  attack,  but are absorbed  by  many organisms.   As a
result, they tend  to concentrate in organisms  and  up  the  food
chain.   Research on  TCDD, an ionic  herbicide residue,  demon-
strated that accumulation was  directly related to  water concen-
trations (0.05  to  1,330 ppb) and averaged  between 400,000 and
2,000,000 times the  water concentration (321).

SYNTHETIC/ORGANIC  CONTAMINANTS

      Recently,  there has been  a great interest in identifying
 synthetic/organic  trace compounds  in water supplies  drawn from

                               141

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 rivers  and  in  other water  bodies  receiving treated wastewater.
 Although  studies  have  been made of the concentrations found in
 various water  systems, neither the environmental pathways nor
 the  potential  health effects  to man of these substances have
 been studied to any great  extent.

     Over 100  synthetic/organic compounds have been identified
 in various  drinking water  sources.  Thirty-six compounds were
 found in  the lower Tennessee  River (Table  64), while 66 were
 identified  and quantified  in  Mississippi River water at New
 Orleans (Table  65 ).   Table 66  lists the results of organic
 analyses  of several other  domestic water supply sources.

     The many  different types of  compounds under discussion here
 make generalizations difficult regarding their environmental
 fate.  For  instance, acetone  is  infinitely soluble  in  water;
 chloroform  is soluble to  about 8,200  mg/£;  carbon tetrachloride
 is soluble  to about 800 mg/l;  and  n-decane is insoluble.   The
 specific gravity of toluene is less than  that of water,  while
 the specific gravity of carbon disulfide  is  greater.   Acetalde-
 hyde is readily metabolized since  it  is  a natural  metabolic
 intermediate, but branched alkyls  are almost  impervious  to
microbial  attack.

     The differences in man-made  synthetic/organic  compounds
exceed the similarities,  but  in  general,  these compounds are
 persistent and  resist microbial  degradation.   Beyond  that
generalization, research  has  been  too limited to discuss
specific compounds in detail.

     Polychlorinated biphenyls (PCB's) are the only class of
synthetic/organic contaminants that have  been studied  in detail.
They are virtually insoluble  in  water, which, combined  with a
high specific gravity and volatility, serves  to keep  solution
PCB concentrations low.  However,  PCB's  are  strongly  adsorbed
onto suspended  particulate matter  and transported through the
water system.   Because of their  heavy, insoluble character and
sediment affinity, they tend  to  accumulate in bottom  sediments.
A comparison of selected  water and sediment  PCB concentrations
from across  the United States  is  presented in Table  67.

     PCB's are  fairly stable  in  fresh-water  systems,  resisting
hydrolysis and  chemical degradation,  and  are  not amenable to
photodegradation (481).  Theoretically,  they  should readily
vaporize from solutions,  but  this  is  prevented by their  tendency
to sink or strongly adsorb onto  suspended matter.   Only  PCB's
that are associated with  floatables or oil  slicks appear to
vaporize to  any great degree.   The lower isomers (four or fewer
chlorine atoms) are somewhat  responsive  to biodegradation, but
the degradation products  are  frequently  more  toxic  than  the  PCB
 itself (481).  The higher isomers  resist  microbial  attack.


                              142

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                            TABLE 64
              ORGANIC COMPOUNDS IDENTIFIED TO DATE
                   FROM LOWER TENNESSEE (615)
Acenaphthene
Allylbenzoate
Anthracene
Benzene
Biphenyl
Butyl benzene
5-Chloro-2-Methyl benzofuran
p-Cresol
Diallyl Adipate
Dibutyl Phthalate
Di phenylacetylene
COMPOUNDS ----------
    Fluorene
    Hexachlorobenzene
    Indene
    o-Methoxybenzoic Acid
    2-Methylanthracene
    2-Methylbiphenyl
    4-Methyldiphenylacetylene
    Methyl Indene (2 isomers)
    1-Methylnaphthalene
    Naphtha!ene
    p-Nonylphenol
    n-Octyl-o-Phthalate
1,1-Diphenylethene
2,6-Di-Tert-Butyl-4-Methylphenol  Pyrene
Ethylbenzene                    Styrene
Ethyl o-Phthalate               1,2-Tetradecanediol
Ethylstyrene                    Toluene
Ethylene Dimethylacrylate       3,4,4-Trimethyl-2-Hexene
Fluoranthene                    Xylene
                               143

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           TABLE  65

 ORGANIC COMPOUND IDENTIFICATIONS

NEW ORLEANS AREA WATER SUPPLY STUDY
            (615)
Highest Measured Concentration
vfl/1
Compound
1
^
3
4
5
6
7
8
9
10
Acetaldehyde
Acetone
Alkylbenzene-Cg fsorcer
Alkylbenzene-Cg isomer
Alkylbenzene-C2 isomer
Alkylbenzene-C3 isomer
Alkylbenzene-C3 isomer
Alkylbenzene-C3 isomer
Atrazine *
(2-chloro-4-ethylamino-
6-isopropylamino-
v-triazina)
Deethylatrazine
(2-chloro-4-amino-
6-isopropylamino-
^.-triazinc)
Carroll ton
Water Plant
D-VOA
D-VOA
0.05
0.33
0.11
0.01
0.04
0.02
5.0
0.51
Jefferson # 1
Water Plant
NE
NE
NO
ND
0.03
NO
0.05
NO
4.7
0.27
Jefferson •? 2
Water Plant
NE
NE
ND
NO
NO
ND
0.02
ND
5.1
0.27
             144

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TABLE  65  (continued)
                                    Highest Measured Concentration
Compound
11
12
13
14
15
16
17
18
19
20
21
Benzyl butyl phthalate*
Bromod i chl oroethane
Bromoform *
Butanone
Carbon disulfide
Carbon tetrachloride
bis-2-Chloroethyl ether*
Chloroform *>a
bis-2-Chl oroi sopropyl
ether *
n-Decane *
Decane-branched isomer
Carrol. Hon
Water Plant
0.64
0-VOA
0.57
D-VOA
D-.VOA
D-VOA
0.07
173
0.18
0.04
0.03
Jefferson # 1
Water Plant
0.81
HE
ND
NE
HE
NE
0.16
NE
0.05
NO
ND
Jefferson f 2
Water Plant
0.73
NE
ND
NE
NE
NE
0.12
NE
0.03
ND
NO
                                   145

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TABLE 65   (continued)
                                       Highest-Measured Concentration
                                          t-g/i
Compound
22
23
24
25
26
27
28
29
30
31
32
Di broraod i chl oroethane
isoiner
Oibromochlorome thane *
Dibutyl phthalate *
2,6-Di-t-butyl-£-
benzoqulnone *
Oichlorobenzene isomer
1,2-01 chl oroethane a
Oichloromethane
Dieldrin **
Diethyl phthalate *
Di(2-ethy1hexy1) phthalate "
Dihexyl phthalate
Carroll ton
Mater Plant
0.33
1.1
0.10
0.22
0.01
8
D-VOA
0.05
0.03
0.10
0.03
Jefferson 9 1
Water Plant
NO
0.30
0.16
0.19
D-RE
NE
NE
0.07
0.03
0.31
ND
Jefferson 1 2
Water Plant
0.63
0.60
0.19
0.23
ND
NE
NE
0.05
0.01
0.06
ND
                                    146

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TABLE  65  (continued)
Highest Measured Concentration
ug/i
Compound
33
34
35
36
37
38
39
40
41
42
43
Dihydrocarvone
Diisobutyl phthalate *
Dimethyl phthalate
Dioctyl adipate
Dipropyl phthalate *
n-Dodecane *
Endrin **
Ethanol
o.-Ethyl toluene *
£-Ethyl toluene *
1, 2, 3, 4, 5, 7, 7-
Heptachloronorbornene *
Carroll ton
Water Plant
0.14
0.59
0.27
0.10
0.07
0.01
0.004
D-VOA
NO
0.02
0.06
Jefferson 3 1
Water Plant
0.06
ND
O.IS
ND
0.13
ND
NYE
NE
0.04
0.03
0.05
Jefferson § 2
Water Plant
0.07
ND
0.18
ND
0.14
ND
NYE
NE
0.02
0.03
0.05
                                  147

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TABLE   65  (continued)
                                      Highest Measured Concentration
Compound
44
45
46
47
48
49
50
51
52
53
54
Heptachloronorbornene
isomer
Hexachloro-1 ,3-butadiene *
Hexachloroethane *
Isophorone *
Limonene *
Kethanol
Methyl faenzoate
3-Methylbutanal
2-Methylpropanal
n-Konane *
n-Pentadecane *
Carroll ton
Water Plan
0.06
0.16
4.4
1.5
0.03
D-VOA
NO
D-VOA
D-VOA
0.03
0.02
Jefferson # 1
Water Plant
0.04
0.27
0.19
2.2
KD
NE
D-RE
NE
NE
ND
ND
Jefferson # 2
Water Plant
0.04
0.21
0.16
2.9
ND
NE
NO
NE
NE
ND
ND
                                    148

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TABLE  65  (continued)
Highest Measured Concentration
pg/i

55
56
57
58
59
60
61
62
63
64
65
66
Compound
Tetrachloroethane
Isomer
Tetrachloroethylene
n-Tetradecane *
Toluene *
1 ,1 ,2-Trichloroethane *
1 ,1 ,2-Trichloroethylene
n-Tridecane *
Trimethyl-trioxo-
hexahydrotriazlne
isomer
Triphenyl phosphate *
n-Undecane *
Undecane-branched isomer
Undecane-branched isomer
Carroll ton
K'ater Plant
0.11
0
0.02
0.08
0.35
D-VOA
0.01
0.07
0.1E
0.02
0.04
0.06
Jefferson 9 1
Water Plant
NO
0.5
ND
0.10
0.45
HE
ND
ND
ND
ND
ND
ND
Oeffsrson £ 2
Water Plant
ND
0.41
ND
ND
0.41
NE
ND
ND
ND
ND
ND
ND
                                    149

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                     KEY  TO SYMBOLS  USED  IN TABLE  65

 Symbols used  in  column headed  "Compound"


 *    While all compounds listed  in  the table v/cre identified by one or
      more methods,  those marked  with this symbol gained added confirma-
      tion by  gas  chromatography  retention time match v/ith an available
      standard of  the compound.

 **   Compounds marked with  this  symbol gained further confirmation by
      gas chromatography  retention time match with available standards on
      each of  three  different columns, polar and non-polar.

 a    The quantitative values for these compounds were obtained on
      Volatile Organics Analysis  by comparison with standards of known
      concentration  at the Water Supply Research Laboratory.  Compound 18
      was detected but not quantified in Tetralin extracts of Carrol lion
      water at Southeast  Environmental Laboratory, but not in Tetralin
      extracts of Jefferson Ho. 1 or Jefferson No. 2.  The latter labora-
      tory did not detect compound 27.


 Symbols  used  in columns headed "Highest  Concentration  Measured"


 D-VOA     These compounds were detected by Volatile Organics
           Analysis - Bellar Technique only.   Quantitative values
           have not yet been obtained.  Ttvi5 method was performed
           only on the Carroll ton water at the Water Supply Research
           Laboratory.

 D-RE       These compounds were detected only  on XAO resin
           extracts in the specific water for  which this symbol
           is used.  Quantitative values v/ere  not obtained from
           the resin extracts.  The compound may have been detected
           and quantified by another method in one or both of the
           other waters examined.

 D          In the one instance where this  symbol  was used the
          compound v/as detected by both the Hater Supply Research
          Laboratory and Southeast Environmental  Research Laboratory
          but not quantified by either laboratory.

NE        This symbol means not examined.  It is  used
          exclusively for some compounds  reported by the Water
          Supply Research Laboratory.   This laboratory did not
          obtain  samples  of v/ater from Jefferson  No.  1  or Jefferson
          No.  2.
                                   150

-------
                     KEY TO TABLE  65   (Continued)
NO        This  symbol means the compound was not detected in
          that  specific water by any of the methods employed.

NYE       Compound  39 was confirmed in Carrollton water carbon
          chloroform extracts shortly before preparation of this
          report.   Jefferson No. 1 and Jefferson No. 2 extracts
          have  not  yet been re-examined specifically for compound 39.
                                  151

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        TABLE  66.  MOLECULAR CONSTITUENTS IDENTIFIED
                   IN  NATURAL WATER SAMPLES (615 )
Constituent
p-Cresol
Diethylene glycol
Ethylene glycol
Glycerine
Glycine
Manni to!
Methyl-a-D-glucopyranoside
Methyl-B-D-glucophranoside
Sucrose
Xylitol
Urea
Inositol
0-Methyl inositol
Linoleic Acid
Oleic Acid
Palmitic Acid
Stearic Acid
2,2' -Bipyridine
Sample.
Source
3
5
5
1,2,3,4,5
1
5
4
4
1,5
5
1,2
1,2,3,4,5
1,2,3,4,5
1,5
1,5
1,5
1
4
Concentration
mg/£
7
1
20
1-20
2
2
30
3
2
1
4
0.5-1
0.3-10
1
1
0.4
0.5
4
al - Lake Marion, 2 - Fort  Loudon  Lake, 3 - Holston River,
 4 - Mississippi River, 5 - Watts Bar Lake
                             152

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TABLE 67.   PCB CONCENTRATIONS IN
  SELECTED WATER COURSES (146)
State
Alaska
Arkansas
Cal ifornia
Connecticut
Hawaii
Georgia
Maryland
Mississippi
New Jersey
Oregon
Pennsyl vania
South Carolina
Texas
Virginia
Washington
West Virginia
Concentration
Water
yg/ i-
ND
ND
0.1 , 0.1
0.1-0.2
ND
--
0.1
ND
0.1
ND
0.2
--
0.1-3.0
0.1
ND
ND
Concentration
Sediment
yg/kg
ND
20-2,400
20-190
40
ND
10-1 ,300
10-1 ,200
50; 170
8-250
15; 140
10-50
30-200
7.9-290
5-80
ND
10
              153

-------
PCB's are thus quite persistent in water/sediment systems,  and
lifetimes of years or even decades have been postulated (481).

     The continued presence of PCB's makes it inevitable that
they will enter the food chain.  As they tend to accumulate in
lipid tissues in higher plants and animals,  it has been
estimated that PCB's will  concentrate up the food chain to  as
much as 10'  times the water concentration (482).

BIOLOGICAL CONTAMINANTS

     An important pathway  for certain communicable disease
transmission to man is the consumption of contaminated water.
Direct disposal of wastewater is the principal contamination
route.  Land disposal of wastewater is not an
important pathway,  as pathogenic organisms have limited mobility
in soil and seldom migrate far enough to contaminate water
supplies (296).  However,  in contrast to their restricted
mobility in soils,  biological contaminants are readily dispersed
and transported by receiving waters.  Consequently, there is a
high potential for direct public contact through drinking or
recreational use.  Wastewater treatment has  diminished this
threat by reducing the number of organisms in the wastewater.
This, combined with natural pathogen mortalities, has greatly
lessened the outbreak of water-borne diseases attributable  to
public water supplies.

     The environmental factors that influence the survival  of
pathogens in fresh water are, in most cases, similar to those
that prevail in marine systems.  These factors will be discussed
in greater detail in the marine water section of this chapter.
Briefly, however, the chief factors influencing survivabi1ity
are temperature, pH, sunlight, toxins, predators, and lack  of
nutrition, which affect pathogens to different degrees.  An
examination of Table 68  reveals that pathogens may survive for
long periods of time and travel great distances before destruc-
tion by environmental factors.

     Pathogenic bacteria are best adapted to survival in the
human body or to conditions resembling those found in the body.
Consequently, natural water systems are a hostile environment.
However, cool water is generally more hospitable than warm  water
because of the depressed metabolism of both  the bacteria and
their predators.  Predatory organisms, especially in slightly
polluted waters, are a major contributor to  bacterial die-off.
For instance, Barua (35) noted that Vibrio choi erae survived
one to two weeks in clean water as opposed to one to two days in
water with a large bacterial population.

     Pathogenic bacteria also suffer from a  lack of proper
nutrition in clean waters; low nutrient levels prevent reproduc-
tion.  Since die-off rates exceed growth rates, the overall

                              154

-------
en
tn
                               TABLE  68.  AVERAGE TIME IN DAYS FOR 99.9% REDUCTION
                           OF ORIGINAL TITER OF  INDICATED MICROORGANISMS IN WATERS (595)
Microorganism


Poliovirus I
ECHO virus 7
ECHO virus 12
Coxsackie virus A9
Aerobacter aerogenes
Escherichia coli
Streptococcus fecal is


28°C
17
12
5
8
6
6
6
Little Mi
River (Oh
20°C
20
16
12
8
8
7
8
ami
io)
4°C
27
26
33
10
15
10
17
Ohi
(
28°C
11
5
3
5
15
5
18
o River
Ohio)
20°C
13
7
5
8
18
5
18


4°C
19
15
19
20
44
11
57

-------
pcpulctiort vn 11 decline,   Other factors affecting die-off are
L": tra\-(C" e.t  r-cc-'ati or. ~r  Sunlight, pH extremes, natural anti-
biotics, end chemical toxins,

     In contrast to bacteria, viruses do not multiply in water
ere.  therefere, their number In a water body can never exceed
the number introduced into that body by waste disposal.  Typi-
cally,  viruses are much more resistant to external environmental
factors (chemical  content, pH,  temperature, time, etc.) and
survive longer than bacteria (136, 198).  It was long suspected
that  f'gcf cca'ld inactivate viruses through some process because
of low virus concentrations in  algae-rich waters.  However, it
is now believed that the  high pH and dissolved oxygen in the
vicinity of  algal  blooms  are responsible for the inactivation.

     Virus inactivation in lake water is further enhanced by
the presence of proteolytic bacteria which degrade the viral
coat  (292).   Coxsfcckie is particularly susceptible to proteolytic
bacteria,  while pcl'O virus is  generally resistant except to
Pseuc-omonas  aeryginosa (292).   Otherwise, the mechanisms rf virus
removal ere  obscure.   lable 69  reports survival times for various
enteric viruses in fresh-water  bodies.

     Transport mechanisms for pathogens include physical current
motion, organism motility, adsorption, ingestion, and aerosoli-
zation.  As  most pathogens readily adsorb onto suspended matter,
sediment pathogen  concentrations may greatly exceed water con-
centrations.   Filter feeding organisms, such as fresh-water
shellfish, tend to concentrate  pathogenic organisms.  Conse-
quenfy, shellfish can be a major factor in the spreading of
certain communicable diseases.
                              156

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TABLE
             IK  WATER

Type of Water
River water





















Impounded fresh
water












• - 	
V i rus
Cp\5*rlc-?f> S-3
ECHO 5
Polio 1
Coxsackie B-3
ECHO 12
ECHO 7
Coxsackie A-9
Polio 2
Polio 3
ECHO 5
Ccxsackie A-9
ECHO 12
Polio 1
Polio 1
ECHC 7 '
Polio 1
Polio 3
Polio 3
Coxsackie A-2
Coxsackie A- 2
Coxsackie B-5
Ccvsackie E
Cnxsarlif F-3
Polio 1
ECHO 7
ECHC 6
Coxsackie A-9
Polio 1
Coxsackie ?
ECHO 12
Polio ?
ECHO ?
ECHO :
Polio ?
Polic ?
ECHO ?
Temr-e
*-fc
7 t: •• •?
7/0.5
7/1
7/1.7
19/3
15/3
10/3
75/3
SO/3
60/3
? C / 3
33/3
19/3
60/3
2t 5
27/3
50/3
67/3
-
-
-
'f T
"7 ,' 1 t
1 / ") . 5
22/3
t t
e/3
2 " ' 3
18/3
H/3
21/3
23/3
2 ": .' c
52/3
52; 3
42/3
r2u.re °f
iS-16
res- c* Daj
P/3
-
-
-
-
-
-
15/3
8/3
15/3
_
-
-
45/3
-
-
18/3
7/1 .3
-
-
24/1
-
_
-
-
-
-
-
-
-
-
-
.
-
-
-

20-25
o •*>
3/3
3/3
3/3
5/3
7/3
8/3
S/3
S / 3
8/3
E/3
12/3
13/3
16/3
16/3
20/3
-
7/2.1
5/2
47/2
_
-
3 ' 3
3/3
4/3
F ••' 3
6/3
6/3
8/3
5/3
10/3
12/3
20 3
21/3
C i- / 3
24/3
                 157

-------
                           SECTION 9

    CONVENTIONAL WATER TREATMENT:  CHEMICAL COAGULATION  AND
          FLOCCULATION FOLLOWED BY SOLIDS SEPARATION
INTRODUCTION

     Chemical coagulation and flocculation,  followed by clari-
fication or filtration, is common water treatment practice for
the treatment of surface waters.  The primary purpose is to
remove suspended and colloidal solids.

     The overall process takes place in three distinct phases.
Coagulation involves destabi1ization of the  colloids by rapid*
mixing of the chemical coagulant with the water in some type
of agitated rapid mix tank.  Retention time  in rapid mixing
is very brief, on the order of a few minutes.  Flocculation
follows in which the wastewater is gently stirred with paddles,
allowing the particles to collide and aggregate into larger
floes.  Depending on temperature, concentration of the solids,
and the type and dosage of coagulant, flocculation requires from
15 minutes to one hour.  Clarification and/or filtration
usually follows, to provide solids separation.

     Commercially available flocculator-clarifier units (often
called solids contact units) combine all  three operations in
a single compartmented tank.  In a typical design, coagulant
is fed and mixed with the wastewater at the  influent pipe;
flocculation occurs in a central cone-shaped skirt where a high
floe concentration is maintained.  Flow passing under the skirt
passes up through a solids blanket and out over surface weirs.
These units are particularly advantageous for lime softening of
hard water, since the precipitated solids help seed the floe,
growing larger crystals of precipitate to provide a thicker
waste sludge.  Recently, flocculator-clarifiershave been receiv-
ing wider application in the chemical treatment of industrial
wastes and surface water supplies.  The major advantages promot-
ing  their use are reduced space requirements and less costly
installation.  However, the unitized nature  of construction
generally results in a sacrifice of operating flexibility.
                               158

-------
     The primary substances used as coagulants and their
reactions are described below:

     1.  Aluminum sulfate + calcium bicarbonate
         A12(S04)3 + 3 Ca(HC03)2 = 3 CaS04 + 2 A1(OH)3 + 6 C02

     2.  Aluminum sulfate + sodium aluminate:
6NaA102 + A14(S04)3 .  18
         6H
                                        8A1(OH). + 3NaSO
     3.  Aluminum chloride (used under exceptional circumstances
         only) :
         2 A1C13 + 3 Ca(HC03)2 = 2 A1(OH)3 + 3 CAC12 + 6 C02

     4.  Aluminum sulfate + hydrated lime-
         A12(S04)3 + 3 Ca(OH)2 = 3 CaS04 + 2 A1(OH)3

     5.  Ferric  sulfate:
         Fe2(S04)3 + 3 Ca(HC03)2 = 2 Fe(OH)3 + 3 CaS04 + 6 C02
Ferric sulfate + hydrated lime:
Fe2 (S04)3+ 3 Ca(OH)2 = 2 Fe(OH)3 + 3 CaS0

Ferrous sulfate:
FeS04 + Ca(HC03)2 = Fe(OH)2 + CaS04 + 2 C

Ferrous sulfate + hydrated lime:
FeS0
    4 + Ca(OH)2 = Fe(OH)2 + CaS04
Ferrous sulfate + chlorine
2 FeS04 + 3 Ca(HCO,)? + C19 = 2 Fe(OH),  + 2 CaSO,  +
CaCl   + 6 C0      ^ 2     2           3          4
     6


     7


     8


     9
     The most commonly used coagulant is Al?(SOA)o .  18 HoO,
which is known as filter alum.   The amount of hydrolysis which
occurs when filter alum is introduced to the water is a function
of the pH of the water, with optimum efficiency achieved at a
pH of 7 to 8(506) .

     Because chemical coagulation and clarification is
probably the most popular water treatment technique,  there
exists a substantial volume of information on this technology.
Table 70 summarizes the available literature located  during the
study.  As shown in the table,  most research work has been
performed on the elemental group of contaminants as many of
the metals are most efficiently removed by chemical precipita-
tion.  Substantial  study of turbidity removal and virus in-
activation/removal  have also been conducted.  With the current
focus on synthetic/organic and  biocidal contaminants  in water
supplies and their potential carcinogenic effects with long-
term ingestion, a surge in research in these areas is anticipated
                              159

-------
     TABLE 70.   LITERATURE  PERTAINING  TO  CHEMICAL  COAGULATION
                            AND  CLARIFICATION
Contaminants
       Reference  Number
Water Quality Parameters
  Asbestos
  COD
  Color
  Hardness
  Suspended solids
  Turbidity
Elemental Contaminants
  Antimony
  Arsenic
  Barium
  Cadmium
  Chromium
  Cobalt
  Iron
  Manganese
  Mercury
  Molybdenum
  Nickel
  Selenium
  Vanadium
374, 375
575
226, 414, 575
141
93
9, 137, 157, 225, 226,  274,  548,  575

537
39, 99, 157, 275, 280,  396,  491,  576,
577
39, 396, 506, 588
39, 157
157
470, 480, 537
130, 157
130, 157
157, 394, 506
537
537
157, 506
537
                              160

-------
TABLE 70  (continued)
Contaminants
Biocidal Contaminants
DDT
D i e 1 d r 1 n
Endrin
Lindan.e
Parathion


537,
537,
537,
546
40
Reference Number

546
546
546


Synthetic/Organic
 Contaminants

  PAH  (Polynuclear
  Aromatic  Hydrocarbons)  284

  PCB                      352

  TTHM (total  trlhalo-
  methanes)                632

Biological Contaminants

  Bacteria                 14, 56,  112,  113,  116, 198, 435, 547,
                           575, 639,  643,  700

  Virus                    112, 113,  547
                               161

-------
WATER QUALITY PARAMETERS

   Asbestos has recently been implicated as a carcinogen of
potential danger to workers breathing the fiber in asbestos
manufacturing plants.  Thus, it is feared that the incidence
of asbestos in drinking water supplies may also be a health
hazard .

   Several studies have investigated the ability of chemical
coagulation followed by clarification and/or filtration to
remove asbestos from water intended for potable purposes.
Lawrence et al. (375)  examined the effectiveness of various
methods:  straight filtration, diatomaceous earth filtration,
chemical coagulation and combinations.  The most effective
method involved chemical coagulation with iron salts and poly-
electrolytes followed by filtration, which resulted in better
than 99.8 percent removal  from water containing 12 x 106
fibers/^  .  The optimum ferric chloride dosage was found to
range from 6 to 8 mg/£ ; satisfactory floes were formed at all
test temperatures.  Other reported removal efficiencies were
reported as follows:


                                          % Asbestos Fiber
             Treatment                       Removal	

   Ferric chloride, polyelectrolyte
   coagulation and filtration                   99.8

   Graded sand filtration only                  90

   Diatomaceous  earth filtration only           96.8

.   Bentanite clay, polyelectrolyte
   coagulation and filtration                   99


     As  a continuation of the above effort, Lawrence and
Zimmermann (374)  studied the optimization of alum and polyelectro'
lyte coagulation for asbestos removal.  Optimum removals were
obtained with alum concentrations of 30 to 50 mg/a and poly-
electrolyte values of 0.3 to 0.6 mg/a .  Asbestos removals of
over 99.9 percent were achieved.   Rapid coagulation and direct
filtration was also evaluated and the performance found to be
comparable to conventional  treatment employing flocculation and
sedimentation.  In addition, a survey of turbidities and fiber
concentrations for several  municipal water supplies indicated
no correlation between these two parameters.

     Shelton and Drewry (575) evaluated the effectiveness of
various  coagulants in the removal of COD from a raw surface
water supply.  Results are summarized in Table 71.


                               162

-------
                    iABLE  71  .  A COMPARISON OF THE EFFECTIVENESS OF THE COAGULANTS TESTED
                                           ON THE RAW SURFACE WATER (575)
CO
Coagulant and
Coagulant Aids
A12(S04)3
FeCl3
Fe2(S04)3 . nH20
Cationic flocculant
A12(S04)3 +
Cationic flocculant
A12(S04)3 " +
t. to
Nonionic aid 1
A12(S04)3 +
Anionic aid 1
A12(S04)3 +
Anionic aid 2

A12(S04)3 +
i. to
Nonionic aid 2
A12(S04)3 +
Na9OAl 90,
C, C* «3
Coagulant
con-
centration
mg/fc
15
34
35
0.56
8 +
0.25
10 +
0.25
10 +
0.2
9 +
0.2

10 +
0.2
10 +
12
""'• - -'--- ~~~ '-"-"-—
Maxi-
mum
Turbidity
Removal
percent
96.50
94.80
90.50
46.0
97.4

97.4

99.65

98.6


97.20

98.70
.••^^^^••i^^B*™™™"*""""""""""^^^^""™
Coagulant
con-
centration
mg/£
20
48
38
0.51
8 +
2.25
10 +
0.5
10 +
0.4
10 +
0.2
71
+
0.4
10 +
9
Maxi-
mum
COD
Removal
percent
43.0
73.0
88.50
26
49.5

59.3

97.5

79.5


85.00

86.00
Optimum
Dosage*
A B
12 14
37 32
65 42
t 1.5
9.2 7.2
0.25 0.25
9 9
0.4 0.16
8.2 |
0.4 t
7.1 1
0.2 |
64 54

0.4 0.4
10 |
Q t
y t
•
         se
        Isoelectric point was not reached with test dosage.
        More than one isoelectrici point was indicated.

-------
       Mey  conducted  tnat aiumirijin suifate was the most effective
  coaguiant  *or  COO removal.   Cationic poi velectrolyte additions
  *«"«  • 'i* '**,;:• ,i  ,.7:'i  i7-,;-rT,; jTjs ,^d , 3' 3dtt9r. results.

       Color  is  caused  by  numus, tannins,  weeds, algae, soluble
  wastes, and  to  a  certain extent,  metals  (632).  In itself, color
  is not a hea tn Jiazard;  however,  it signals the presence of dis^
  solved organics and metals  that may be of some health concern

  Ii«??nie/E?!?arC£erS-eval?ated C°1or removal  in the same inves-
  tigation (575).   Ferric  chloride  was found  to  perform erratically
  at differing dosages.  Excellent  removals  were achieved at a    *
  35 aig/i. out it dosages  around 35 m^/ i' ,n«j  50  mg/t!,  color was
  significantly  increased.  A  study by Mangravite et!  al  (414)
  showed t>jat removal o* V^>7  ,^d r0,? s^!jrce  Qf color  $n ^^
  >jp3,»i-si jy ir.,.-.ji- ^:j-.,;-t  p-CJIi0:;(j ,;ie  3J.ne  hi  ^ percentaqe of
  removals as the conventional  coagulation/sedimentation  technique
  but at .a rar.9 0,  5 tc ?J  ,,rnes  faster    F  , t    and 8       (226)
  investigated the  use of  aTum  with 13 coagulant aids  for color
 reroova,.   v,?r.rnam aljsn Jasages  ranged  from  20  to  25  mg^ and
 successfully lowered the color  concentration to  below five stan-
 dard  units.   The  use of  irot  saUs,  oxViation, adsorption, or
 po;/7ie"5 j:^3   ;:a'J ,TJ: i.vvavi  :l:s  !d>e^ of removal.
       jr-jTjss -i.n-:/r ,•;,!   jn- ^.>    -oas  ^-edom^na fitly)  via lime
 soaa prtjcipitdtirfa scjfiening is a common practice  at  many water
                        soft water has g-na^My  been  considered
 f   f •T-^'ii  ?T t::u: ? z raauces cne usage of  soap  and detergents
 tastes  better,  and reduces scaling and precipitation  in  pipes  '
 rnnn*'1CM«??'i1:2r3    * -v«* ' •* " •  3 ™* "e •- - " -  stjuies,  summarized  by
 Looper  (141)  have  discovered  an apparent  inverse  relationship
 between  hardness  arjjftenrtg process may nave to be  reevaluated.
                 ,           il  ">'o.n w-i-ie- supplies by coated
and uncoated diatomite  filter  was evaluated by Burns et al.  (93)
They  found that  special  polyelectrolyte coatings were useful
For a final polishing filter process, but that these aids were
not as effective as  conventional  filter aids where large amounts
or suspended solids  had  to  be  removed.

     T-jr!3icHt/  is  J  iT-vn^  nejiur-eo  *at«r q^jtlity parameter
inversely related  to the  visual  clarity of the water.  Turbidity
is caused by clay  and other  colloidal matter which in themselves
are or no health concern.   However,  nea^y metals, virus, and
bacteria may be adsorbed  onto  the clay  particles, and the removal
of turbidity can be of  imoortance in  regards to potential  long!
term nealth effects.  because  of  ,ts  poouUrisy as a quality test
many studies or turbt^ty removal  lave  been  performed as         '
summarized below.  Robtnson  (543  compared the  effectiveness of
                               164

-------
alum versus polyelectrolytes for  removal  of  turbidity  from muddy
surface water.  Figure 4  summarizes  the  De!"fo~
-------
4.  The optimum paddle speed ranges between 40 and  50
    rpm.

5.  The optimum flocculation time was approximately 30
    mi n.

6.  This study revealed that the significant interactions
    between the independent variables (alum dosage, floc-
    culation time, and paddle speed)  can be utilized in  more
    efficient water treatment.   For example, a higher
    percentage removal of turbidity can be obtained by
    using low alum dosage and increasing the flocculation
    time and/or paddle speed.  On the other hand,  high
    alum dosages and reduced flocculation times and/or  paddle
    speeds can be utilized.

7.  The study shows the importance of the following equip-
    ment and methods in the removal of turbidity in water
    treatment plants:
    a

    b
             Variable speed flocculator paddles.

             Multiple flocculation basins that can be used in
             series or parallel operation.

         c.  The use of jar tests to determine the optimum alum
             dosage continuously during the operation of water
             treatment plants.

     Gruninger et al . (274) compared the performance of ferric
chloride versus alum as the primary coagulant and found that
the combination of 8 mg/A Fed- + 4 mg/s, bentonite clay + 0.25
mg/ji polymer provided comparable performance to the system with
alum and clay; there was approximately 95-98 percent turbidity
removal.

     Reference 157 summarizes the performance of various treat-
ment technologies in removing turbidity.  These results are -

     •  Plain sedimentation:  50 to 95 percent, depending
        totally on the settling characteristics of solids;

     •  Coagulation with sedimentation:  80 to 99 percent;

     •  Rapid sand filtration:  80 to 99 percent with influent
        turbidity of 10 JTU or less;

     0  Slow sand filtration:  80 to 99 percent with influent
        turbidity of 10 JTU or less;

     •  Diatomite filtration:  80 to 99 percent with influent
        turbidity of less than 10 JTU.

                               166

-------
     Shelton and Drewry  (575)  analyzed the effectiveness  of
different cationic,  nonionic,  and anionic polyelectrolytes  in
reducing turbidity.  Table  71, presented earlier, displays their
results.  Aluminum sulfate  with  anionic coagulant aids was  found
to be the most effective, achieving 99+ percent removal  at  a
10 mg/£ dosage.  Frissora  (225)  evaluated the performance of
rapid multimedia filtration alone on turbidity removal and
achieved removals of 96  to  99.7  percent at high loading  rates  of
4 to 16 gpm/ft2.  Conley (137)  also studied rapid filtration
preceded by chemical coagulation and settling, for turbidity
removal at a number  of water  treatment plants around  the country,
Table 72 summarizes  the  results  of his study; removals ranged
from 80 to 97 percent and  averaged 94 percent.

ELEMENTAL CONTAMINANTS

     Many elemental  contaminants are readily removed  by  chemical
coagulation and subsequent  solids separation steps (settling  or
filtration).  As some of the  elemental  contaminants are  being
more closely reviewed for  possible long-term health effects,  the
importance of chemical coagulation as a removal process  becomes
more pronounced .

  TABLE  72.  TYPICAL THREE-MEDIA HIGH-RATE FILTRATION PLANT PERFORMANCE
Location
Regina, Sask.
Siler City, N.C.
Pasadena, Tex. (industrial)
Corvallis, Ore.
Ocaquan, Va.
Samoa, Ca. (industrial)
Fort Lauderdale, Fla.
Knoxville, Tenn.
Albany, Ore.
Long view, Tex.
Paris, Tex.
Newport, Ore.
Norristown, Pa.
Springfield, Mo.
Winnetka, 111.
Stanton, Del.
Turbidity
Applied Filtered
JTU JTU
0.5
1
3
3
1
10
1
1
2
4
10
3
6
1.5
2
2
0.1
0.2
0.5
0.2
0.1
0.5
0.1
0.2
0.2
0.2
0.3
0.2
0.3
0.2
0.3
0.2
Filter
Rate
gpm/ft2*
4
5
6
3
4
5
4
5t
5
3
3
4
4
4»5
5
4
Filter
Runs
hr
30
30
40
50
48
18
80
60
20
48
50
20
45
24
15
30
Backwash
Water
percent
2
2
1
1
1
2
1
1
2
2
2
3
1
1
2
3
  * Typical summer peak daily flow rate.   Hourly peaks
    are generally in  the range of 4-6 gmp/sq ft.

  t Under test.  Some filters are out of  service so
    that rate could be increased on remaining filters.
                                167

-------
       Arsenic  is  one  element  being  closely  watched  in  water
  thnHS  3S H\hSSKa  relat1vely  h19"  toxicity,  accumulates  in
  the  body,  and  has  been  associated  with  the occurrence of  cancer
  (39)   Several  studies on  arsenic removal are  available.   Some
  JlSn^T-5 21 black-f°°t  disease  and skin cancer  have  been
  reported  in the  southwest  part of  Taiwan.   According  to
  statistical data,  there is a  close  relationship  between these
  diseases  and the high arsenic content (0.6 to 2.0  mg/£) in
  deep-well  water  used for drinking  (577).  Since there is  no other

  iirl  SlJhJST  S°UrCe  !un  the area' some P^^ical and  econo-
  mical method to  remove  the arsenic  compounds was urgently
  needed    To satisfy this need, Shen (576) performed  a lengthy
  ISSl^JV* *reatabH1ty tests to evaluate  the arsenic  Removal
  capability of coagulation/settling/filtration processes
  Initial coagulant  tests showed ferric chloride to  be  the best
  chemical,  achieving 92 percent As removal  at a 30  mq/£ dosaae
  Subsequent testing, however,  showed that these removals could'
  be improved by preoxidation before coagulation.   Adding 20 nq/t
  of chlorine and then coagulating with 50 mg/£ of ferric chloride
  provided the best results, achieving 98.7 percent As remova?
 *ff0HKu             (275)sh°wed that As removal was
 affected by PH and doses of suitable coagulants.  Arsenic
 adsorption onto ferric hydroxide exceeded adsorption onto
 ?™miHnhin/J?lde-  1^ "?0tt? C0a9ula"ts, increased dosages
 rfoJj^e  •  9/ } r
                              168

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     The toxicity of antimony is  similar to  arsenic,  although
less acute.   Very little research has  been conducted  related
to Sb,  as other metals appear to  be of more  importance from
a health-effects standpoint.   Lime coagulation has  been shown  to
provide Sb removals of better than 90  percent from  wastewater
effluent (537).   Similar removals  may be possible in water
supply treatment, but no data was found.

     Barium is  a toxin that acts  as a  muscle stimulant.  As
such, it strongly affects the heart muscles and causes high
blood pressure  and nerve blockage (39).  Barium removal -
only for wastewater treatment - was reported by several re-
searchers.  Sigworth and Smith (588) found during pilot waste-
water plant tests that lime coagulation and settling was an
effective method, resulting in a 99 percent Ba removal.  Dosage
rates were 45 mg/£ FeCla, 260 mg/£ lime plus 20 mg/t FeCl3 for
the  low  lime test, and 600 mg/£  lime for the high lime run.
Logsdon  (396) found improved removals with the lime softening
process.  Treatment efficiency was pH dependent, increasing
to  a maximum of  98 percent at pH 10.5,  and dropping off at
higher  pH values.  Barium is not appreciably removed  by ferric
or  alum  coagulation.

     Cadmium has  a  high  toxic potential,  accumulates  in  the kid-
 ney and  liver,  and  has  been  suggested  as  a  causative  factor in
 high blood  pressure  (157).   Only minute traces  of  cadmium  are
 found  in natural  waters.  However,  several  industries  discharge
 cadmium in  their wastewaters,  including metallurgical  alloying,
 ceramics manufacture,  electroplating,  inorganic  pigments,
 textile printing,- chemical industries,  and  acid  mine  drainage.
 Very little  data are  available regarding  the  use of  coagulation
 for Cd  removal  at water treatment  plants.   The  summary reference
(157pists removals at  50 to 90  percent with  coagulation followed
 by  filtration.   Unpublished  data developed  by EPA  indicates
 that lime softening  and ferric  sulphate coagulation  above  pH  8
 achieves Cd  removals  of over 98  percent.

      Chromium  in the hexavalent  form  is highly toxic to man
 and has been shown to be carcinogenic to man when  inhaled.
 Volkert and Associates, In  a study for EPA (157), summarized
 that coagulation and sedimentation with filtration is capable
 of removing 50 to 90 percent of the insoluble chromium (Cr)
 forms  present  in water supplies.

      The hexavalent form is  much more difficult to remove with
 typical water  treatment coagulants than is the trivalent form.
 It  is desirable, therefore,  to reduce the chromium present
 to  trivalent prior to treatment.  Laboratory studies  by EPA
 (unpublished)  indicate that trivalent  chromium  is removed at
 better  than 95 percent levels by ferric sulphate  up  to pH
 9.5, removed at 90 percent levels by alum up to pH 8.5, and
 removed at 98 percent level  by  lime softening at pH  from  10

                                169

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to 11.5.  Hexavalent chromium, however, is not effectively
removed by any of these coagulants.  Cobalt (Co) concentration
in potable water sources seldom reaches levels that require
special consideration.  Cobalt is currently best treated by
lime coagulation, although as much as 2 mg/t may be left in
the effluent (537).  Nilsson (480) found that lime coagulation
was capable of achieving 88 percent removal of cobalt.  Another
study  (470) found that cobalt precipitation could be enhanced
by the addition of chitosan or a chelate as a polishing agent.
An EPA study (537) concluded that similar precipitation techni-
ques are also applicable to molybdenum (Mo), nickel (Ni), and
vanadium (V) removal.

     Iron and manganese, often found together, are important
constituents of potable water supplies because they can import
unwanted aesthetic qualities.   From a health standpoint, how-
ever,  iron and manganese do not pose any significant threat
in the concentrations  normally found in surface and ground-
water  supplies.  Therefore, removal of these constituents will
not be discussed in any depth here.  Effective removal can be
provided by aeration or more commonly, by chemical precipitation,
sedimentation, and filtration (130).

     Recent attention  has been focused on the contamination of
water  supplies by organic and inorganic mercury (Hg) by
industrial  discharges.   Fortunately, recent rests by the EPA of
273 water supplies across the country showed very low mercury
levels in nearly all of them.   Even so, the performance of
conventional  water treatment technologies and new techniques for
removing Hg from water is of interest.  Logsdon and Symons (394)
investigated  the efficiency of conventional water treatment
processes in  removing  Hg.  Bench scale studies of chemical
coagulation and settling yielded the following conclusions:

     1.  Mercury removal during coagulation was related
         mainly to adsorption  of mercury onto the
         turbid-causing agents in the water.

     2.  In raw waters  with low turbidity, ferric sulfate
         was  more effective than alum for removal of
         inorganic mercury.  Removals ranged from 40 to
         60 percent over a turbidity range of 2 to 100
         JTU's.

     3.  Removal  by coagulation or adsorption onto turbidity-
         causing agents was less for methyl mercury than
         for  inorganic  mercury.
                              170

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     4.   Inorganic mercury removal  by  softening  was  most
         effective in the pH range  of  10.7  to  11.4 and
         is thought to be related  to adsorption  onto
         magnesium hydroxide floe.

     5.   Methyl  mercury was not removed by  softening.

     The authors concluded by stating  that  as  long as  environ-
mental levels of mercury in raw water  remain low (near  drink-
ing water standards), extremely high removals  will not  be
required, and conventional technology  should be  sufficient.

     Molybdenum can occur naturally in drinking  water supplies
at concentrations up to 20 vg/£ due to weathering of minerals.
It can also be found in water as a result of waste discharges
from industries related to the manufacture of glassware,
ceramics, printing inks, electrical equipment, and certain
steel alloys.  Virtually no data relative to molybdenum removal
from water supplies are available, because molybdenum is not
currently seen as a primary health hazard.

     Nickel occurs naturally at concentrations up to 0.072 mg/£
with an  average concentration of about 0.005 mg/£.  Wastewater
discharges from industries associated with nickel-plating,
nickel alloying,  storage  battery manufacturing,  organic  hydro-
genation, and the manufacture of nickel-chrome resistance wire
can  contribute  to  the  presence  of  nickel in water sources (21).
In  large doses, Ni can  be  harmful;  however, in this country,
natural  concentrations  are  low, and lime coagulation appears  to
be  successful in  removing  large percentages of Ni from waste-
water.   No literature  pertinent to  Ni  removal by water treatment
facilities was  found.

      Alum  and ferric  sulfate  coagulation and  lime softening
are  only moderately  effective  for  selenite  (Se+^)  removal,
and  are  largely ineffective  for selenate  (Se+°)  removal  (396).
Studies  with  ferric  sulfate  (30 mg/£)  at a  pH of 5.5 yielded
removals of  85  percent from river  water  containing  0.03  mgSe H/£.
Removals decreased as the pH  increased.  The  maximum  achievable
Se+4 removal  with alum (100 mg/£,  pH 6.9) was  32  percent.  A
maximum  removal  of 45 percent was  obtained  with  lime  softening.
No conventional  method achieved greater  than  10  percent  removal
of Se+6.

      No  data were located relative to vanadium  removal  from
water supplies.  In wastewater treatment,  however,  very good
vanadium removals were achieved via coagulation with iron or
 aluminum salts  or chitosan polymers (537).
                                171

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310CIDAL CONTAMINANTS

     Recently, there has been increased a'.v.j"e>ie ?•> cf the
potential health hazards of biocidals.  Limited data, however,
are available in the literature regarding the removal of
these constituents from water supplies by chemical coagulation
Robeck et al. (546) studied the effects of various water treat-
ment processes on pesticides.  Their results, in regards to
pesticide removal via chemical coagulation (alum) and filtra-
tion, are shown in Table 73  below.
         TABLE  73.  PERCENTAGE OF PESTICIDE REMOVED BY
                 CONVENTIONAL WATER TREATMENT (546)
  Pesti cide
Load - ppb
                                          10
            25
Lindane
Dieldrin
DDT
Parathion
2, 4, 5-Tester
Endri n

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SYNTHETIC/ORGANIC CONTAMINANTS

     In recent years, con.e^n  ias  }«ei  exsf*>52J  omr  tne
possible occurrence of certj'n ci-^ao-^jo'<'c  .-^mounds  In
drinking water (World Health Organization,  1964).   A group
of compounds which has received  particular  attention  is  the
polynuclear (polycyclic) aromatic  hydrocarbons  (PAH),  some
of which are potent carcinogens  under certain conditions.   It
is, however, far from certain  that  these  compounds  are signi-
ficant when present in the trice  mounts  found  In drinking
water.  Clearly, further research  is T??ded  into  both  the
levels and health effects of :3A,i  i i  uie en* < ronmenc ('-'84j .

     Harrison et al. c jnc 1 ujs  \Z84; :   'Tie  --^1 ••'•ab'i M ty  of  much
of the information concerning  tna  removal  of  PAH  by conven-
tional water treatment processes  is  open  to  considerable  doubt.
Field experiments hava frequently  ignored  retention times
within the works, and hence been  rende-ed  unreliable at  the
sampling stage.  Laboratory studies  nave  commonly used unreal-
istic high concentrations of PAH,  and the  high  removals  achieved
may be largely explained afcen D/  :<•«.?  'ow  sjiubiiity  af  the
PAH themselves.  Further analytical  work  is  required  in  this
field, and fundamental studies o*  the cheoncaT  changes that
occur upon chlorinati aa  jf *ie.>'i  co»n': ju 7 Js  i:  'o«» concentrations
are necessary.  Increasing water  reuse  makes  the  ne-?d  for t*ii$
type of information par tic -j • ar' y  aci-.i  '

     After the EPA disclosed its  ^inj:; !ig$  o'  or^oe^!?s
Mclndoe (435) summari *ea rase-arci  ? n  :i*j area  as  fc!-cws:

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    t  Work by the U.S.  Army Engineering Research and
       Development Laboratories at Fort Belvoir,  Virginia,
       showed that a diatomite filter using a coarse grade
       of filter aid was capable not only of 100  percent
       removal of the entamoeba cysts,  but also of partial
       removal of other  pathogenic organisms.  Work done
       at Rutgers University has shown  that even  the
       coarsest grade of diatomite gave coliform  removals
       of greater than 50 percent for influent levels of
       210 to 1300/100 ml.   Finer grades gave "complete"
       coliform removals of influent levels up to several
       thousand per 100  mi.

    9  Work by Chang (112,  113), Hunter (313), and
       others with solutions of iron salts added  to bacteria-
       contaminated water has indicated a reaction takes
       place between the iron ions and  the protein sheath
       of both bacterial and viral organisms.  Subsequent
       removal of the iron  by the diatomite MgO process
       has produced total count reductions on the order of
       99 percent, with  fecal strep and Escherichia coli
       counts of zero.

    t  Waters so clarified  would be expected to be readily
       disinfected by usual practices.


CONTAMINANTS

     Amirhor and Englebrecht (14) analyzed the potential
use of uncoated and polyelectrolyte -aided diatomaceous earth
filtration for bacterial virus removal.  They concluded that
uncoated DE filtration was  not effective for virus removal,
but that precoating of cationic polyelectrolyte greatly
improved removals.  Certain variables such as pH, level and
concentration of polyelectrolyte coating, and virus concentra-
tion affected removals.

     Wolf et al. (700) conducted a large-scale pilot study of
virus removal by both lime  and alum.  They demonstrated that
virus removals from secondary effluents by alum coagulation-
sedimentation and coagulation-sedimentation-filtration pro-
cesses are essentially the  same as described in the literature
using smaller-scale processes.  Removals of bacterial virus
as high as 99.845 percent for coagulation-sedimentation and
99.985 percent for coagulation-sedimentarion-fi1tration pro-
cesses were observed at  an  A1:P ratio of 7:1.

     At a lower alum dose there was a marked decrease in virus
removals.  At an A1:P ratio of 0.44:1,  removals of only 46
percent of f2 coliphage  and 63 percent of polio virus by the
coagulation-sedimentation process per se were observed.

                               174

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     High lime treatment of secondary effluents achieved
very high degrees of virus removal, but the percentage has not
yet been quantified.

     Englebrecht and Chaudhuri (116) conducted a study to extend
the knowledge in this field.   Their conclusions follow:

     1.  Chemical coagulation and flocculation is an
         effective process in removing viruses from
         water.  Removals in the range of 98.0 to 99.9
         percent can be expected.

     2.  The presence of bivalent cations like calcium
         and magnesium up to a concentration of 50 mg/£
         each does not interfere with the efficiency of
         the process.

     3.  The efficiency of virus removal is reduced when
         the raw water contains  organic matter.

     4.  Intelligent use of commercially available
         cationic polyelectrolytes with or without
         hydrolyzed metal ions may markedly increase
         the efficiency of the coagulation and floccula-
         tion  process  in  removing  virus.

     5.  Virus particles remain  active in the  settled
         sludge  following their  removal from water by
         coagulation and flocculation, and can be recovered
         from  the floe by various  eluants.  Therefore,
         proper  care should be taken  in sludge disposal.

     Thorup et al. (643) conducted a study to determine  the
effectiveness  of polyelectrolytes  used as coagulant aids
for the  removal  of virus from  artificial ly seeded water.   They
found  that the cationic polyelectrolyte performed more
acceptably than  the an ionic and  nonionic types and was  benefi-
cial in  aiding floe formation  under  conditions of poor  coagula-
tion.   However,  the 80 to 94  percent  removal achieved  under
these  circumstances was well  below the 99+ percent usually
considered acceptable.  In instances  of adequate coagulation,
however, cationic polyelectrolytes did not increase virus re-
moval  beyond the levels obtained with unaided  Al2(S04)3 or
^62(504)3 coagulation.

     Shelton and Drewry  (575)  performed a literature search of
virus  (f2 bacteriophage)  removal via  coagulation and,  based
on  the  results,  studied the effectiveness of different chemical
coagulants and polyelectrolytes  for  this purpose.   Their
conclusions were:
                               175

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     1.  Aluminum sulfate, ferric chloride, and ferric
        sulfate are the most promising of the group
        of  primary coagulants  tested, from the stand-
        point  of f2 bacteriophage  removal, all produc-
        ing greater than  99  percent  removal.  Aluminum
        sulfate  is considered  to be  the  most  effective
        coagulant, whereas  ferric  chloride and ferric
        sulfate  are  less  effective.

     2.  The cationic  polyelectrolyte tested  is not
        satisfactory  as  a primary  coagulant  because  of
         its poor  floe formation  and  settling  characteris-
        tics.   Virus  removals  with the  cationic  flocculant
        were only  moderate  (92 percent).

     3.   Anionic,  nonionic,  and cationic  polyelectrolytes
         have only  minor  significance in  virus removal.
         It is noted,  however,  that the  anionic  coagulant
         aids are useful  in  widening  the  effective dosage
         range for  good virus reduction.   The nonionic
         coagulant  aids give moderately  better results,
         which are  attributable to  an ability to  form more
         dense and  "sticky"  floe.   This  improvement  of  virus
         removal  is indirect, because the nonionic poly-
         electrolytes  do  not form a virus-ion complex with
         the virus  protein coat.   The cationic coagulant aid
         produces a moderate improvement  in  virus removal;
         however, it  is questionable  if  this  improvement
         would be economically  justifiable for a  full-
         scale operation.

     4.   The use of sodium aluminate  with aluminum sulfate
         does cause a  marked increase in  virus removal,
         to 99.9 percent  overall.   This  increase, however,
         could be used only  for "special-case" situations,
         since the  sodium aluminate dosage for optimum  virus
         removal  is not compatible  (by a  factor  of 3) with
         turbidity  and COD optimums.

     Thayer and Sproul (639)  of  the  University of  Maine  did
extensive  research  concerning the effects of  water softening
upon virus inactivation.   Their primary  objective was the
determination of the  effect  of  chemical  precipitation in water
softening  upon bacterial  viruses.   Inactivation  of T2 virus
varied widely, with the best results, on  the  order of 99.999
percent inactivation,  occurring when  magnesium hydroxide was
the only precipitate  formed.  The standard excess lime-soda-
ash process also produced good  results with  about 99.45  per-
cent virus reduction.
                              176

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     Lime f 1 occulation  with rapid sand filtration,  a long-used
standard water-treatment, method,  was investigated for its
virus-removal  characteristics by  Berg et al.  (56) at the
Cincinnati Water Research Lab.   Conclusions  based on their
study using polio virus I (nacuine) exclusively were that
(1) flocculation of secondary effluent yielded up to 99.86
percent removal  of the  virus, dependent upon  the coagulant
dose and the pH level  attained, and (2) the  total removal  by
lime flocculation and  rapid sand  filtration  through an 8-in-
deep filter achieved a  maximum of 99.997 percent.

     The Journal of the Sanitary  Engineering  Division, ASCE,
published an article in 1961  summarizing the  virus  work done
up to that time (198).   Table 74  shows the results  of this
work.  As shown, the dosage of flocculant alone is  not a
measure of the efficiency of the  process.

     Robeck et al. (547) investigated the fate of human viruses
in rapid filtration processes with and without flocculation and
settling.  They found  that if low alum doses  were fed just
ahead of the dual-media filter (operating at  6 or 2 gpm/ft^),
more than 98 percent of the virus was removed.  When the alum
dose was increased and  conventional flocculators and settling
added, removals were increased to over 99 percent.   When turbid
water was treated, a floe  breakthrough was  usually accompanied
by an increase  in virus penetration.  Polyelectrolyte doses
as low as 0.05 mg/£ increased floe strength  and helped  to
prevent such breakthroughs.

     The current state  of knowledge indicates that  chemical
flocculation, settling, and filtration are effective in remov-
ing virus from water.   Removals of 99*percent have been  reported
under proper operating  conditions.  However,  more research  is
still needed in the area to fully determine the most effective
doses of coagulants and coagulant aids, the physiochemical
effects of turbidity,  pH, temperature, and colloidal charge,
and to develop  optimal  operating parameters.

     Chang et al . (113)  performed comprehensive studies  of the
dynamics of removal of bacterial  virus by aluminum  sulfate
flocculation.   From their observations they concluded:

     1.  Flocculation by aluminum sulfate can remove high
         percentages of virus, and within the zone  of
         flocculation,  higher doses produced greater
         efficiency.

     2.  The virus is concentrated  in  the floe sediment
         and is not destroyed, but  only  temporarily
         inactivated.    It will become  active again, if
         dissociated   from  the  aluminum.
                               177

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             TABLE  74.  REDUCTION OF HUMAN ENTERIC  VIRUSES  IN
                      WATER BY CHEMICAL FLOCCULATION (.198)

Virus
Polio

Polio






Infectious
hepatitis6
Coxsackie A5
Coxsackie A2
(purified)





Type of Water
Tap
Raw
River






Distilled

Spring
Ohio River
(16-255ppm
turbidity)




Stages
1
1
1

1
1

1

1

1
1
1

2

2

Coagulant
Added*
ppm
100
100
136

410
136-273

273-546

69

28-45
15
25

15
15*
25
25*
Floe Amount
or
Description





0.4-1.03
mi per 1
1.5-2.2
mi per 1



Good
Very good

Very good
Very good
Very good
Very good
Virus Removal
Little6
Some0
Some to
significantd
Some
Little to some

Significant

Little to some

Some
95.7% at 25°C
95.9% at 5°C

98.6% at 25°C
99.8% at 25°C
99.6% at 5°C
99.9% at 25°C
 Alum except where marked with an asterisk; asterisks
   indicate ferHc chloride.
DProbably less  than  25%.
:Probably less  than  50%.
JMore than 50%.
2Gauze-strained  fecal  suspension in distilled water.
                                    178

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     3.   Virus inactivation is believed to be the result
         of the formation of an aluminum protein salt
         in the virus.

     Chang et al.  performed another study O12) evaluating the
efficiencies of alum and ferric chloride in removing coxsackie
and bacterial viruses.   They analyzed the effects of coagulant
dosage,  pH, and rate and method of stirring on virus removal.
A 40 mg/£ dose of  Al2(S04)3 yielded an 86.3 percent removal of
coxsackie virus and a 93.5 percent removal of bacterial virus.
Under similar testing conditions, 20 and 40 mg/£ of FeCK
facilitated the following removal percentages: 96.6* coxsackie
virus and 99.3 bacterial virus, and 98.14 coxsackie and 99.9
bacterial virus.
                               179

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                                           DISINFECTION
INTRODUCTION

     Disinfection refers to the inactivation  or  destruction of
pathogenic microorganisms.  Disinfectants  (chlorine,  ozone,
ultraviolet and ionizing radiation) also have secondary applica-
tions, particularly as oxidzrts for the removal  of organic con-
taminants.  Both applications are  included in the  literature
pertaining to the treatment of drinking water with disinfectants
(Table  75).

     In the United States, the traditional  disinfectant is
chlorine, which rf Lfe^ate:1.' .   It  Is a  powerful
oxidant.  Both its germlcical and  oxidizing properties  seem to be
the ^esult cf the *r-"!rpt- rr r* ffvf"?,1 ^ree ^adicaTs  in water
(HCp. OH, HOi*). v«r-;-t v'  fitted, c'niost  all organic compounds.

     bl trtv,del cr.c • ; 7. ; r 9 ^cc-.Efi6n have  been  used  in  pilot
plant and small industrial applications.   Like ozone, they seem
to act. by fcrir,1r?c c ff'f* :'" f'-rf "cf'T'cels in water, which can
attacl; crgan-'c bones.  i,1 ii'-cv u';tt is  incapable  of acting  at more
than a fev. centimeter de-rtr. prc'  both forms  of  radiation  are
highly susceptible tc interference from turbidity  and suspended
matter.  Ionizing radiation requires  radioisotopes and  the con-
commitant shieldinc cnc el cti-^-ii.e  Scfety precautions.

     AH r^ the d*<" r ft •; tf T *. < tf«r cl 5 ?c;vantapes that prevent
any of then* frofri be".r.o urr, vera'; ly applicable.  For a given
situation the rhc-r.f dfpprc'f "e^cr-v  or the water  quality, types
of microorganisms 1r tt-e water, desirability  of  nondi sinfection
applications, and erst.
                               180

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                          TABLE 75.   LITERATURE REVIEWED PERTAINING TO HATER DISINFECTION
               Contaminant
                                              Chlor1nat1on
     Water Quality Parameters
          /\rnrrr>r> i 3
          BOP,  '0,0, TOC  .
 332, 366, 616, 688
 332, 555, 616
     Elemental Contaminants
          Iron
          Manganese
     Biocldai  Contaminants
          Chlorinated
          hydrocarbons
_,         Organo-phosphorus
oo         Carbamates

     Synthetic/Organic Contaminants
          PCBs
          General

     Biological Contaminants
          Viruses, general
         Coliforms
         E. Coli
         Clostridium
         Protozoa
 91,  157
284, 319, 555, 616


55, 111, 136, 242, 284,
332, 399, 463, 547, 600,
616
111, 366, 537, 555
55, 332, 351, 660

111, 660
                                 Reference Number
                                    Ozonation
 3^2, 351, 455, 660
 3-2


 157, 402, 465
 157, 351, 465
 91,  157,  332
157, 284, 465


111, 242, 332, 402,
463, 465, 600, 660

61, 111, 283, 332, 537
351, 465, 660
660
111, 332, 660
                                                                                               Radiochenrical
                            469
 157
 157
 157


 157, 352
 157
111,  469,  656

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WATER QUALITY PARAMETERS

     Although disinfectants are seldom specifically employed
to remove any of the water quality parameters,  there are certain
chemical reactions that make the idea feasible.   The reactions  of
chlorine with ammonia are the best known.   If allowed to go to
completion, the ammonia will be oxidized to nitrogen gas and  will
thus be removed from the water.  Ozone does not  react with
ammonia ( 332 )•  Ammonia is seldom an issue, though, as it is
not a common constituent of most water supplies.

     The organics, as represented by BOD,  COD,  and total organic
carbon, in drinking water are susceptible  to oxidation by dis-
infectants.  However, reactions other than oxidation may produce
potentially hazardous compounds.  For instance,  Rook (555) and
McClanahan ( 332 ) reported that chlorine  reacted with humic  and
fulvic substances, forming chlorinated organic   compounds.
These chlorinated compounds are much more  resistant than the
precursor compounds to both biodegradation and  chemical  oxida-
tion.  Consequently they persist in a water supply that  is not
treated any further than chlorination.  Some of  the chlorinated
compounds formed are suspected to have carcinogenic properties.

     Ozone is even more reactive toward organic  compounds than
is chlorine.  With ozone, though, the reactions  are almost
exclusively oxidation, with few if any hazardous  compounds formed
in side reactions.  The formation of ozonides and similar com-
pounds has been postulated, but there has  been  no evidence to
date demonstrating their formation during  the ozonation  of water.
Morris (465) reported an increase in BOD after  ozonation and
attributed it to the breakdown of nonbiodegradable organic
molecules into simple, degradable compounds.

     Murphy (469) recently demonstrated that gamma radiation  had
an oxidizing effect on organic compounds similar  to that of
ozone.  Ultraviolet radiation theoretically has  a similar effect.

     It should be noted that nonbiological contaminants  inter-
fere with the primary disinfection role of these  chemicals by
consuming the disinfectants.  To achieve proper disinfection
in highly organic waters, for instance, requires  large  increases
in applied dosages.  Some water-borne disease outbreaks  are
attributed to improper disinfection of highly organic water
supplies.

ELEMENTAL CONTAMINANTS

     In general, the disinfectants have no effect on elemental
concentrations.  Elements   would have to  be in  a reduced state
before oxidizing disinfectants could have  an impact.  This is
not likely in most drinking  water supplies.  Exceptions are
                              182

-------
iron and manganese, which are more soluble in their lower oxida-
tion states.  Morris (465)  reported that ozone readily oxidized
soluble iron and manganese  to the insoluble oxides, which could
then be removed by sedimentation or filtration.

     Trivalent chromium can be oxidized to the hexavalent form,
which is more toxic and difficult to remove with conventional
coagulation/filtration processes.

BIOCIDAL CONTAMINANTS

     Chlorinated hydrocarbon biocides are generally resistant
to chemical  oxidations.  Stone et al. (537) reported that
chlorine was not a particularly effective oxidant for such bio-
cides.  Ozone was more effective, but removal efficiencies
varied widely from 16 to 93 percent, depending on the type of
biocide, ozone concentration, and contact time (Table  76).
Stone et al . reported other ozone studies that yielded 50
percent removal of endrin,  75 percent removal of lindane, and
approximately 100 percent removal of dieldrin and aldrin.  They
also stated  that ultraviolet radiation could completely elimi-
nate carbamate biocides, reduce aldrin by 45 percent, and reduce
endrin and dieldrin by 18 percent.

     Buescher et al. (91 )  studied the chemical  oxidation of
chlorinated  hydrocarbons in water.  They concluded  the following:

     t  Lindane concentrations in aqueous solutions were
        readily decreased by ozonation and only partially
        affected by potassium permanganate.  Treatment with
        chl orination, peroxides, and aeration had no measurable
        effects.

     •  Aldrin in aqueous solutions was readily attacked by
        chlorination, potassium permanganate, ozone and aera-
        tion; peroxides had no measurable effects.

     •  Dieldrin concentrations in aqueous solutions were
        decreased by ozonation and aeration.

     •  Lindane and aldrin  in aqueous solution were found to
        be volatile.  The degree of volatility may be an
        indication of the susceptability of that pesticide to
        chemical treatment.

     •  Lindane in the presence of other naturally occurring
        trace organics found in river water was readily attacked
        by ozonation, though aeration had only a minor effect.
                               183

-------
oo
                                         TABLE  76.  EFFECT OF OZONATION ON
                                     CHLORINATED HYDROCARBON INSECTICIDES (537)
Y-BHC Dieldrin DDT TOE (ODD)
Time of
Ozonation
5
10
20
5
10
20
Before After Before After Before After Before
Ozone Ozonation Ozonation Ozonation Ozonation Ozonation Ozonation Ozonation
Absorbed
mg/t ug/*
8.8 1.32 0.88 1.29 1.08
18.3 1.39 0.81 1.30 0.66
36.0 1.31 0.34 1.31 0.22
11.7 2.00 0.54 2.00
20.0 2.00 0.46 2.00
38.2 2.00 0.14 2.00
Aftei
Ozonat



0.62
0.43
0.13

-------
SYNTHETIC/ORGANIC  CONTAMINANTS

     As previously mentioned under "Water Quality Parameters,"
both chlorine and  ozone readily react with dissolved organics.
However, synthetic organics  are often more resistant to oxida-
tion than the natural  organics.  Rosenblatt (  332 )  indicated
that chlorine reacted  with many organics to give both chlorina-
ted and oxidation  products,  but that there was no reaction with
many others (Table  77).   Ozone is an effective oxidant against
the phenolics and  organic nitrogen compounds,  but not against
many of the simpler organic  molecules, such as ethanol .
Harrison et al.  (284)  reported  that chlorine was more effective
than ozone against benzo(a)pyrene.

     Many of these synthetic organics, such as nitrobenzene,
benzo(a)pyrene   oniline, and ethyl benzene are reportedly
carcinogenic.  While these chemicals are seldom found in
drinking water supplies at concentrations exceeding a few ppm,
the postulated no-threshold-dose character of many carcinogens
makes even one molecule a potential hazard.  Note also that
chlorine is suspected  of producing chlorinated organic compounds
which may themselves be carcinogenic.

     Kinoshita and Sunada (352) investigated the effects of
irradation on PCB  in water.   They concluded that PCB in aqueous
microparticulate colloidal solution is destroyed by ionizing
irradiation (up to 95  percent), but that its resistance to
radiation is far greater than other chlorinated hydrocarbons
used as pentachlorophenol or DDT, and other pesticides such as
parathion.  They also  found that the acute toxicity of the
irradiated PCB solution was far less than the nonirradiated
solution for striped shrimps.

BIOLOGICAL CONTAMINANTS

     The major application of disinfectants is against biological
contaminants.  In this light, the disinfectants  have been eyaluated
primarily on their effectiveness  in  controlling biologicals
(e.g.,  bacteria, viruses, protozoa,  parasitic worms).

     Chlorine is the traditional disinfectant in the United
States.  It is effective to some extent  against all  types of
pathogenic organisms found  in water.  Bacterial  kills  of at
least  99 percent are considered normal  (537), and 4  to 5 log
reductions are not unusual .  Both  Sobsey  (  600  ) and Long
(399 )  reported virus  reductions  of  up  to  99.99  percent.
Reference  136 summarized  r-esearch  on  virus  destruction  by
chlorine  as  shown  in Table  78.  Chlorine can  be  effective when
used with  filtration against free-swimming  protozoa  and  para-
sitic  worms.  However, chlorine is  relatively  ineffectual
against their ova  and  cysts  that  are  resistant  to  oxidation.
Chlorine  has the  further  advantage  of persistence   given  a


                               185

-------
           TABLE  77  .  PROBABLE REACTION PRODUCTS OF
          CHLORINE AND SOME TYPICAL ORGANIC COMPOUNDS
           FOUND  IN  POLLUTED WATER SUPPLIES (332  )
Organic Compound
Probable Reaction Products
Alcohols
   Methanol
   Isopropanol
   tert-Batanol

Ketones
   Acetone

Benzene and Derivatives
   Benzene
   Toluene
   Ethyl benzene
   Benzole acid

Phenol and Phenoli cs
   Phenol


   m-Cresol


   Hydroquinone
Organic Nitrogen Compounds
   Aniline
   Dimethyl ami ne
   Nitrobenzene
None
None
None
None
None
None
None
None
Mono-, di-, and trichlorophenols;
non-aromatic oxidation products

Mono-, di-, and trichlorocresols;
non-aromatic oxidation products

p-Benzoquinone, non-aromatic
oxidation products


Mono-, di-, and trichloroani1ines;
non-aromatic oxidation products

N-Chlorodimethylamine, oxidation
products

None
                              186

-------
TABLE 78.   VIRICIDAL EFFICIENCY OF
   FREE  CHLORINE  IN WATER (136)
Investigator
Chang et al.



Neefe et al.



Lensen et al.



Clarke and
Kabler









Weidenkopf






Kelly and
Sanderson








Virus
Part, purif.
Theiler's
virus in
tap water
Feces-borne
Inf. Hepat.
virus in
dist. water
Purif.
Polio II in
dist. and
lake water
Purif.
Coxsackie
A2 in
demand- free
water






Purif.
Polio I
(Ma honey)
in demand-
free water


Purif.
Polio I
(Ma honey)
in demand-
free water
Purif.
Polio III
(Saukett)
in demand -
free water
Temp.
°C
25-27
25-27


Room



19-25



3-6
3-6
3-6
3-6
3-6
3-6
27-29
27-29
27-29
27-29
27-29
0
0
0
0
0
0
0
25-28
25-28



25-28
25-28



Final
PH
6.5-7.0
6.5-7.0


6.7-6.8



7.4-7.9



6.9-7.1
6.8-7.1
6.9-7.1
8.8-9.0
8.8-9.0
8.8-9.0
6.9-7.1
6.9-7.1
8.8-9.0
8.8-9.0
8.8-9.0
6.0
6.0
7.0
7.0
8.5
8.5
8.5
7.0
9.0



7.0
9.0



Free Chlo-
rine
mg per £
4.0-6.0
4.0-6.0


3.25



1.0-1.5



0.58-0.62
1.9-2.2
3.8-4.2
1.9-2.0
3.7-4.3
7.4-8.3
0.16-0.18
0.44-0.58
0.10-0.18
0.27-0.32
0.92-1.0
0.39
0.80
0.23
0.53
0.53
1.95
5.00
0.21-0.30
0.21-0.30



0.11-0.20
0.11-0.20



Virus Destruction
98.6% in 10 min
99% in 5 min


30 min cont. time
protected all of 12
volunteers

10 min cont. time
protected all of 164
inoc". mice

99.6% in 10 min
99.6% in 4 min
99.6% in 2h min
99.6% in 24 min
99.6% in 9 min
99.6% in 5 min
99.6% in 4 min
99.6% in 3 min
99.6% in 10 min
99.6% in 7 min
99.6% in 3 min
99.6% in 3% min
99.6% in l*s min
99.6% in 8 min
99.6% in 4*s min
99.6% in 16 min
99.6% in lh min
99.6% in 3 min
99.9% in 3 min
99.9% in 8 min



99.9% in 2 min
99.9% in 16 min



               187

-------
TABLE  78 (continued)
Free

Investigator
Kelly and
Sanderson
(cont'd)


Clarke et al .





Virus
Purif.
Coxsackie
B5 in
demand-free
water
Purif.
Adenovirus
3 in BOD
demand-free
water
Temp.
°C
25-28
25-28
1-5
1-5

25
25
4
4



7
9
7
8

8
6
8
6

Final
pH
.0
.0
.0
.0

.8-9.0
.9-7.1
.8-9.0
.9-7.1

Chlo-




rine

0
0
0
0

0
0
0
0

mg
.21
per £
-0.30
.21-0.30
.21
.21

.20
.20
.20
.20

-0.30
-0.30






Virus
99
99
99
99

99
99
99
99

.9%
.9%
.9%
.9%

.8%
.8%
o
-------
sufficiently large dose, a low residual  chlorine concentration
will  remain in the water after treatment,  providing  continued
disinfectant action.   This prevents regrowth and protects  against
accidental  contamination during distribution.

     Despite chlorine's widespread use and some reports of
effective virus kill,  other reports are less optimistic about  its
performance against virus.  Clarke et al.  (129) and  Sobsey (600)
reported the isolation of viruses in chlorinated drinking  water
in Paris (1 pfu/300£)  and South Africa (1  pfu/10-fc).   In view of
the fact that only one to two viruses of some types  are suffi-
cient to cause infection, anything less than 100 percent inacti-
vation may be unacceptable.  But with chlorine, even the absence
of any "living" viruses still may not be acceptable.  McClanahan
(429) reported that chlorine removes the protein coat of a
virus - thus rendering the virus technically nonviable - but may
leave the infectious  nucleic acid core intact.   Consequently,  a
water supply free of  any living viruses may still be infectious.

     Ozone is equally as effective as chlorine against bacteria
and viruses and has a much faster reaction rate.  Once the
proper "threshold" ozone dose is applied (usually less than
5 mg/£), the bactericidal action is almost instantaneous.   Tests
have shown ozone to be between 600 and 3,000 times more rapid
than chlorine in its  destruction of bacteria (429).   McClanahan
(429) was unable to recover viable nucleic acids from ozonated
water, suggesting that virus destruction was complete, as  opposed
to the action of chlorine.  Venosa (660) reported that protozoal
cysts resistant to chlorine were easily inactivated by ozone.
Furthermore, the biocidal character of ozone is not affected by
pH, as is the biocidal character of chlorine.

     Ozone is not without problems; however, ozone  leaves no
 residual.  It has a  fairly short half-life in water and rapidly
 loses all disinfectant ability.  Experience in Europe has
 revealed few problems along these lines, but the added margin
 of safety with chlorine has worked against the adoption of
 ozone in the United  States.  The versatility of ozone and its
 relatively greater disinfecting ability has led to the suggestion
 that initial ozonation could be followed by low-level chlorina-
 tion to provide a residual.  However, little research has been
 conducted along these lines.

     Murphy (469) and Vajdic (656 ) both reported that gamma
 radiation was as good a disinfectant as chlorine against
 bacteria and was somewhat better against the more  chlorine-
 resistant biologicals.  Ultraviolet is a proven bactericide,
 but research on other biocidal characteristics has been limited.
 Nevertheless, any radiation treatment suffers from operational
 difficulties, and, like ozone, provides no residuals.
                               189

-------
    The sanitation districts of Los Angeles County are in the
final stages of an extensive study for EPA and the California
State Water Resources Board.  This study titled "The Pomona
Virus Study," has evaluated virus removals by various combina-
tions of tertiary treatment processes  and followed by chlori-
nation or ozonation.  Their conclusions in part are that the
majority of virus inactivation occurs during disinfection and
the main function of the preceeding tertiary unit processes
was that of removing substances (turbidity, organics, etc.)
which interfere  with efficient disinfection.  In virus seeding
experiments involving combined chlorine residuals of 5 mg/s,
average seed virus removals of 4.7 to 5.1 logs were achieved.
With 10 mg/£ of combined chlorine residuals,5.2 logs of virus
removal were achieved.  In seeding experiments involving ozona-
tion, average log virus removals ranged from 5.1 to 5.4 logs.
                              190

-------
                           SECTION 10

           ADVANCED WATER TREATMENT:   ADSORPTION  ONTO
              ACTIVATED CARBON AND OTHER MATERIALS
INTRODUCTION

     Activated carbon adsorption (or simply carbon  adsorption)
is employed to remove color,  odor,  taste,  and refractory organic
compounds from water.  Many water treatment plants  presently pass
their effluent through a carbon column or  fine-grain carbon bed
to polish the final  product.   Available data indicate that carbon
adsorption is an effective method for removing synthetic and
natural  organic contaminants, particularly chlorinated hydro-
carbons  and organophosphorus  pesticides, from water.  Carbon
adsorption may also  be used to remove some metals.   There is some
adsorption of the free metal, but metal removal  can be greatly
enhanced by the addition of an organic chelating agent prior to
passage  through the  carbon.  The carbon will readily adsorb the
chelating agent, thereby also removing the complexed metal.

     The literature  that has  been reviewed on the effective-
ness of  the adsorption process in potable  water treatment is
summarized in Table    79.  The major portion of the research
to date  has involved tertiary wastewater treatment application,
although there has been substantial  work also in the water
treatment field as shown in Table 79.  With the recent
concern  over residual organics in U.S. water supplies, one
can anticipate increased activity in both  pilot and full-
scale activated carbon systems for treating water supplies.

     In  addition to  activated carbon, synthetic polymeric adsor-
bents have been extensively tested and show promise for
potable  water treatment.  They are not widely used in water
treatment plants but have been tested in pilot-scale instal-
lations.  Some tests have indicated higher removal  efficiencies
for synthetic adsorbents than for activated carbon for some
contaminants.  Inorganic adsorbents, such  as clays and
magnetite, are also capable of contaminant removal.

WATER QUALITY PARAMETERS

     Activated carbon adsorption was used following chemical
coagulation and rapid sand filtration at the much-publicized
Windhoek, South Africa, water treatment plant.  The influent

                               191

-------
     TABLE 79.  LITERATURE REVIEWED PERTAINING TO ADSORPTION
Contaminant	Reference Number	
Water Quality Parameters
  Ammonia                 442, 610
  BOD                     515, 610
  COD                     515
  Chlorides               442, 551, 589
  Nitrates                442, 610
  Nitrites                610
  Oil  and grease          316
  Phosphates              515
  Sulfates                610
  Sulfides                378
  Suspended solids        515
  Taste and odors         70, 157, 276, 282, 316, 378,  442,  524
  Turbidity               70, 276, 442
Elemental  Contaminants
  Arsenic                 467, 506
  Barium                  506
  Cadmium                 467
  Chromium                506
  Iron                    442
  Lead                    467
  Mercury                 157, 309, 394,  467,  506,  640, 641
  Selenium                506
                                192

-------
TABLE 79  (continued)
Contaminant	Reference  Number	
Elemental Contaminants
  Silica                  126
Biocidal  Contaminants
  DDT                     157, 192, 537,  546,  589
  DDE                     192
  Aldrin                  157, 192, 537
  Dieldrin                157, 192, 316,  537,  546
  Endrin                  157, 192, 537,  546
  Carbamates              193
  Chlorinated
  hydrocarbons            157, 192, 316,  537,  551,  589
  Organophos              157, 192, 467,  537
  Herbicides              157, 467
  Lindane                 546
  Other (general)         157, 262, 546,  570
                          157, 262, 276,  284,  316,  352, 442,
                          455, 467, 506,  537,  589,  610, 632
Biological Contaminants
  Polio virus             467
  Virus                   467, 498
                               193

-------
to this plant was treated wastewater which was subsequently
mixed with surface water for direct reuse.  Stander and
Funke (610) reported on the effluent quality through the
pilot plant.  The concentration of ammonia nitrogen in the
effluent was lowered from 0.3 to 0.1 mg/l by passage through
an activated carbon filter.  ABS and BOD were also signi-
ficantly reduced, 82 and 67 percent, respectively.

     Table  80 , from Medlar (442), summarizes water quality
analysis data from several water treatment plants in New
England employing granular activated carbon filters.  Two
of these plants  (Amesbury and Scituate) use carbon for both
filtration and adsorption, while the remaining four use
carbon for adsorption only.  At each plant, the carbon signi-
ficantly reduced ammonia levels, as between 33 and 100 percent
of the influent ammonia was removed.

     Phillips and Shell (515) presented a study of the
effectiveness of granular activated carbon and other general
contaminants in removing BOD.  The study was conducted at a
pilot water plant treating wastewater effluent by chemical
coagulation, filtration, and passage through 16-ft carbon
columns.  Data are presented in Table   81 .  BOD removal by
the carbon columns averaged 33 percent, while COD was
reduced 80 percent.


          TABLE   81.   ACTIVATED CARBON FILTRATION AT
              COLORADO SPRINGS PILOT PLANT (515)


                  Influent       Effluent         Removal

BOD5
COD
SS
P04
ABS
(ma/£
3
41
4
2
0.9
)
2
8
3
1
0.03
m
33
80
25
50
97
     Activated carbon is highly efficient for removing non-
colloidal, soluble, aromatic-structured color sources.
David Volkert and Associates (157) indicated that
the carbon removal  efficiency for color-producing substances
is 100 percent of methylene-blue active substances.   Table 80
shows that the color removal efficiency of carbon filters
in six water treatment plants was nearly 100 percent
(Medlar,   442).              Activated carbon has also been
used industrially for decolorizing organic dye waste effluents
                              194

-------
                                TABLE 80.   SUMMARY OF WATER QUALITY ANALYSIS  DATA
                                       FROM ACTIVATED GRANULAR CARBON  (442)
VO
CJl

Color (APHA): Raw
Finished
Turbidity (N.T.U.): Raw
Finished
Iron (mg/£): Raw
Unfinished
Odor ( ton) : Raw
Unfinished
Specific Conductance
(ymhos/cm) : Raw
Unfinished
Nitrate (mg/t): Raw
Unfinished
Ammonia (mg/£): Raw
Unfinished
Silica (mg/l): Raw
Unfinished
Ames bury
Mass.
115
0
14.5
0.2
3.5
0.03
3
0
155
230
0.0
0.0
0.7
0.0
11.0
9.6
Newburyport
Mass.
50
0
2
0
0.25
0.16
2
0
102
280
0.0
0.5
.02
.01
4.6
5.4
Scituate
Mass.
250
5
4
0.12
1.57
0.05
3
0
150
268
0.2
0.2
0.22
0.13
7.7
8.3
Somerset
Mass.
30
2
K8
.13
.35
.05
1
0
76
107
0,1
0.2
.07
.02
,7
.8
Manchester
N.H.
20
0
1
0
0.4
trace
1
0
—
—
__
—
Burlington
Mass.
34
0
1.0
0,2
0.51
0,10
3
0
190
235
0,4
0.4
0.21
0,14


-------
 Recently, the nonionic polymeric adsorbents, such as Amberlite
 XAD-7, have been gaining popularity for this purpose (589).

      While Table  80 and the operation at Windhoek  (610)
 show that both organic and ammonia nitrogen were reduced by
 carbon adsorption, they also show that oxides of nitrogen
 (nitrate and nitrite) were not reduced.

      Oils derived from natural, domestic, or industrial sources
 may occasionally be found in wastewater effluents and in water
 supplies.  Hyndshaw (316) reported that petroleum products
 are very quickly adsorbed from water by activated carbon.
 He stated that for emergencies, such as gasoline or oil
 spills, large quantities of powdered activated carbon will
 remove the hydrocarbons.

      Reduction of phosphates  as P04  from  2 mg/l in  the  carbon
 filter influent  to  an  effluent concentration of 1  mg/£  is  shown
 in Table  81   (515).   Sulfate  as S04  was not  reduced from its
 concentration  of  220  mg/l by  carbon  filtration  at  the Windhoek
 plant.   However,  sulfides in  the  form  of  hydrogen  sulfide,
 and polysulfides  that  result  from  the  reaction  of  chlorine
 with  hydrogen  sulfide  were  removed  from well  water,  according
 to Lee  (378).  The  removal  was  indirectly  evidenced  by  the
 destruction  of sulfide  odor  in  the water  supply  and  resulted
 from  a  catalytic  reaction with  the carbon  rather than from
 adsorption.

      Activated carbon  is  commonly used  for removing  tastes
 and odors  from water.   Undesirable odors  in  water are caused
 by the  vapors  from many chemicals, including  halogens,
 sulfides,  ammonia, turpentine,  phenols  and cresols,  picrates,
 and various  hydrocarbons  and  unsaturated organic compounds,
 some  of which have not  been identified.  Tastes  and  odors
 are also  caused by substances produced  by  living microorganisms
 or decaying organic matter.   Some inorganic  substances,  such
 as  metal  ions in  high concentrations (especially iron)
 also  impart taste and odor to water.  Removal of many tastes
 and odors with activated carbon approaches 100 percent.
 Successful taste  and odor removal from  a municipal water
 supply by carbon  bed filters was demonstrated in Buckingham,
 England (Hager, 276).  The water was taken from  a river
 that runs through farmland and  had an earthy taste that
 resisted chlorination; clarification and sand filtration; and
 experimentation with ozone,  permanganate,  and chlorine
 At Goleta, California, taste and odor in the water supply
were also eliminated by passage through granular activated
 carbon beds (276).  Popalisky  and Pogge (524) reported that
 powdered activated carbon was used at a water plant treating
Missouri River water to eliminate taste and odor caused  by
microorganic  compounds.   The compounds  and their concentrations
were not identified.


                              196

-------
     Hansen (282)  reported that installation of granular carbon
filters at Mount Clemens,  Michigan,  completely removed  the  septic
and phenol tastes  and odors that were present in the Clinton
River water supply during  runoff periods.   Granite City, Illinois,
reported a similar experience (70).   The dosage of activated
carbon required to remove  taste and  odor is influenced  by chlorine
application.   Generally, carbon should be applied before chlo-
r i n a t i o n (316).

     Many pesticides and herbicides  produce tastes and  odors
when present only  in very  small concentrations in water.
Hyndshaw (316)  used the beta isomer  of benzene hexachloride
to illustrate the  influence of a small concentration of a
biocide on the  taste and odor quality of water.  This substance,
when present in amounts as little as 17 ppb in odor-free water,
gives a threshold  odor number (TON)  of 8.  (The threshold
number denotes  the number  of volumes of odor-free water
required to dilute the odor concentration to a point where
the odor is just barely perceptible.)  Other organic pesticides
and their concentrations and subsequent effects upon taste
and odor are shown in Table 82  (316).


         TABLE  82.  ODOR  IMPARTED TO ODOR-FREE WATER
              BY PESTICIDES AND HERBICIDES (316)
Substance
Toxaphene
2,4 D (isoctyl)
2,2 D
D-D
Rothane
Chi ordane
BHC
Concentration
ppm
0.84
2.0
92.5
0.0235
50.0
0.07
0.0175
Odor
TON
6
17
4
17
Nil
140
8
     A simple study employing the threshold odor test gave
evidence of the reduction of these compounds by activated
carbon.  The amount of activated carbon required to reduce the
odor of each compound to a palatable level is presented in
Table  83 (316).
                                197

-------
      TABLE   83.   ACTIVATED  CARBON  REQUIRED  TO  REDUCE
         ODORS  CAUSED  BY  PESTICIDES AND  HERBICIDES
               TO  PALATABLE  LEVELS  (316)

Substance
Parathion
37 gamma BHC
Malathion
2,4 D
DDT
•
Concentration
of substance
PDm
10
25
2
6
5

Odor
TON
50
70
50
50
70
Carbon
Dosage
PPm
20
15
20
40
4
Odor
after Carbon
TON
4
1 .4
4
3
3
     Significant reduction in turbidity and suspended solids
concentration is also effected with activated carbon.  The
data in Table  80 show that turbidity is
reduced both at plants where granular activated carbon is
used for filtration and adsorption and where it is used for
adsorption only.  Passage of water through 16-ft carbon
columns effected 25 percent removal of suspended solids at
Colorado Springs (Table 81) (515).

     Turbidity removal is essentially complete  at Nitro,
West Virginia, where activated carbon has replaced sand in
the filters (276).   Final effluent JTU's are typically less
than 0.1.   At Granite City, Illinois, Blanck and Sulick ( 70)
report that suspended solids removal  by carbon  filtration
exceeds that achieved with sand filters.

ELEMENTAL  CONTAMINANTS

     Although little data from municipal water  purification
applications are available, it appears that activated carbon
can provide some removal  of heavy metals.  Direct adsorption
provides some removal, but efficiencies can be  increased  to
nearly 100 percent by adding an organic chelatlng agent
(537).   The carbon removes the complex by adsorbing the organic
agent,  removing the metal along with it.

     Patterson (506) cited evidence that filtration of water
containing 0.2 mg/£ arsenic through a charcoal  bed yielded
an effluent containing 0.06 mg/l of arsenic, or 70 percent
removal.  He cited another report of 40 percent reduction of
arsenite by activated carbon from an initial concentration of
0.5 mg/l to a concentration of 0.3 mg/£.  Morton and Sawyer
(467) tested heavy metal  adsorption during filtration
through a  granular bed of attapulgite clay.  Data are presented
                              198

-------
in Table  84  that show the amounts of metals  remaining in  the
effluent after filtration of various quantities of water at
two different rates.   The initial  solutions contained 1  mg/£
of each metal.  Arsenic was reduced from 0.97 and 0.98 mg/£ to
0.02 and 0.03 mg/£ upon filtration of 2.5 volumes of water
per volume of bed.
    TABLE  84 .   REMOVAL OF HEAVY METALS BY PERCOLATION WITH
      GRANULAR LOW VOLATILE MATTER ATTAPULGITE CLAY (467)
Rat
io o
Percola
Vol ume


Initial



2.
5.
10.
f Volume
te to
Bed

Recoveries
in
Effluent


Concentration 0.
5 0.
0 0.
8 0.
As

97
02
12
56


1
0
0
0
Cd

.00
.01
.01
.01

(
Slow
1
0
0
0
Pb
ppm)
Rate*
.06
.01
.01
.01


1
0
0
0
Hg

.11



.004
.01
.11
6
6
* 960 gal/ton clay/hour.
f 2,880 gal/ton clay/hour
                                        Fast Rate"1"
Initial Concentration
2.5
5.0
12.6
0.98
0.03
0.16
0.68
1 .00
0.01
0.01
0.01
1 .06
0.01
0.01
0.01
1 .11
0.010
0.072
0.152
      In  a  study cited  by  Patterson  (506),  carbon  adsorption
 did  not  improve barium removal efficiency  over  that  achieved
 with  chemical  coagulation  and  clarification.   Patterson  notes
 that  others  have  also  found  poor  removal efficiency  for  barium.
                                    presented  in  Table
                                    and  was  unaffected
 84 (467)
by the
     Cadmium removal  data are also
Removal  of 99 percent was achieved
changes  in flow volume and rate.

     Some success has been reported from pilot plant work on
chromate removal by activated carbon.  Patterson (506)
reported on a study of metal removal from municipal wastewater
plant effluent, in which initial hexavalent chromium levels
of 0.09 to 0.19 mg/£ were reduced to 0.04 mg/£ or less.  The
average effluent concentration reported was 0.017 mg/£.

                              199

-------
 Initial  hexavalent chromium levels of 5 mg/£ were reduced to
 0.09 mg/£ following carbon adsorption.   Patterson noted that
 it appears that activated carbon may not be equally effec-
 tive at  higher chromate levels.

      Table 80   reports  removal  of iron  at six water treatment
 plants  by granular activated  carbon filtration.   Removal  effi-
 ciencies  ranged from 99 percent  to 36 percent.

      Lead removal  is shown in  Table  84  for adsorption  onto
 attapulgite  clay.   Over 99 percent removal  was  achieved at
 all  flow  volumes  and rates tested.

      Mercury adsorption has been studied extensively.   In
 Table 84  ,  it  is  shown  that adsorption  onto attapulgite clay
 of over 99  percent was  achieved  after filtration  of 2.5
 volumes of water  per volume of  bed.   Removals  decreased to
 86 percent removal  as 12.6 volumes  per  volume  of  bed were
 filtered.  Logsdon and  Symons  (394)  conducted  jar tests
 using powdered  activated  carbon.   Increasing  carbon dosages
 increased  removal  of both  inorganic  and  organic  (methyl)
 mercury.   Organic  mercury  removal  was more efficient  than  inorganic
 mercury removal for  a given dosage  of powdered activated
 carbon at  effluent concentrations  less  than  2  ppb.   Residual
 concentrations  of  0.8 ppb  of inorganic  and  0.2 ppb  of methyl
 mercury were achieved.   Further  tests were  performed in
 which powdered  carbon was  added  just  before  alum  coagulation
 to  improve mercury  removal.  Removal  by  alum alone  was  about
 40  percent,  whereas  removal with  65 mg/l of  activated carbon
 plus 30 mg/£ of alum was  in excess  of 70 percent  with an  ini-
 tial mercury concentration of 9.3  ppb.

     The capacity  of granular activated  carbon for  removing
 mercury from water was  also evaluated by  pumping  mercury
 solutions through  columns  (394).  Average influent  concentra-
 tions ranged from  20 to 29 ppb.  Mercury  removals declined
 as the number of bed volumes (based on gross void space)  of
 water treated increased.   Columns with 3.5-min contact  times
 removed 80 percent of the  inorganic mercury for up  to 15,000
 bed volumes of water and 80 percent of the methyl mercury  for
 up to 25,000 bed volumes treated.  Evaluation of  carbon column
 performance at 80 percent  removal indicated that  as contact
 time in the column increased,  the amount of mercury adsorbed
 by the carbon increased.  Also, granular activated  carbon
adsorbed  more methyl mercury than it did inorganic  mercury per
gram of adsorbent.  This behavior was expected, since acti-
vated carbon has a high  capacity to adsorb organics.

     Thiem (640) also conducted jar tests on mercury adsorp-
tion using powdered activated  carbon.  Solutions containing
10 ppb mercury  were brought into equilibrium with various
carbon dosages.  Less than 30  percent of the mercury was

                            200

-------
adsorbed at a carbon dosage of 10 mg/l at pH 7.   When 100
mg/£ of carbon was applied to the test solution, removal
approached 80 percent.  Removal  decreased with increasing
pH, with best removal occurring  at pH 7.   The addition of
chelating agents such as EDTA or tannic acid prior to contact
with the carbon increased adsorption.  Concentrations of as
little as 0.02 mg/£ of EDTA or 1 mg/l of tannic  acid increased
removals from 10 to 30 percent,  depending upon the carbon
dosage that was applied and the  pH of the system.

     Patterson (506)  summarized the data on activated carbon
removal of mercury, saying that the highest percentage removals
(80 to 95 percent) are achieved  with more concentrated mercury
solutions.  However, lowest effluent mercury results from
treatment of less concentrated waters, although the  relative
efficiency is less.  Thus carbon treatment of initial mercury
below  1 ppb yields an efficiency of removal of  less  than
70 percent, but effluent mercury is  below 0.25 ppb.  Carbon treat-
ment of initial mercury concentrations of 5 to  10 ppb yields
about  80 percent removal and effluent levels of below 2
ppb.   Carbon treatment of initial mercury concentrations
between 10 and 100 ppb yields 90 percent or greater  effi-
ciency.

     Poor selenium removal from well water  by activated  carbon
has been reported  in  one case cited  by Patterson  (506).
Removal was  less  than 4 percent.  Poor or no  reduction  of
silica has also been  shown by the data from  six operating  water
purification  plants  employing carbon  adsorption and  filtra-
tion  (442).

BIOCIDAL CONTAMINANTS

     As with  other  synthetic-organic  compounds, some of  the
organic  pesticides  and  herbici'des that are  resistant to  removal
by conventional treatment  techniques  are  effectively removed
by adsorption.   David Volkert and  Associates (157)
cited  evidence  that  over  99  percent  of  the  following chlorinated
hydrocarbons  can  be  adsorbed  by activated  carbon:

         DDT
         Aldrin
         D i e 1 d r i n
         Endrin
         Chlordane
         Heptaclor epoxide
         Lindane
         Methoxychlor
         Toxaphene
                                201

-------
     Laboratory studies cited by Stone (537) have shown that
the following reductions in chlorinated hydrocarbon concen-
trations can be achieved by contacting with appropriate
doses of activated carbon (Table  85):
     TABLE  85.  ACTIVATED CARBON REMOVALS OF CHLORINATED
     HYDROCARBONS ACHIEVED IN LABORATORY EXPERIMENTS (537)
Substance
Chi orinated
hydrocarbons
DDT
DDT
A 1 d r i n
A 1 d r i n
Aldrin
D i e 1 d r i n
Die! dri n
Dieldri n
Endri n
Endrin
Chlordane
Li ndane
Li ndane
Li ndane
Initial
Concentration

6.3
5
5
6.6
5
-
-
0.5-1
4.4.
5
0.5-1
50
10
25
1

ppb
ppm
ppm
ppb
ppm
t

0 ppb
ppb
ppm
0 ppb
ppm
ppb
ppb
ppb
Treated
Concentration

0.04-0.11 ppb
-
-
-
-
-
-
0.25 ppb
-
-
0.25 ppb
-
1 ppb
-
0.05 ppb
Percent
Reduction

98-99
90
76
90
85
99
99
50-97
99
86
50-97
99
90
90
95
Activated carbon removals of several pesticides are well
illustrated by results of laboratory studies cited by the
California State Water Resources Control Board (615)
shown in Table  86 .
TABLE
Carbon
Dosaae (ma/£)
Control
1.0
2.0
2.5
5.0
10.0
12.5
25.0
50.0
86.
REMOVAL
CARBON
Aldrin
48
26
15
12
6
4
.3
.4
Endri
62
15
3
1
0
0
OF SPECIF
ADSORPTION
Re si
n Dieldrin
.4
.5
.56
.22
19
6.3
2.4
1.1
1C TOXIC
( 615)
dual
DDT
41
41
21
3.
MATER
IALS
(ppb)
ODD DDE
7
56
6.
3.
2.
0.
0.
9
7
2
45
35
38
34
29
12
3.
1.
0.
BY
Toxaphene
155
147
80
31
2.7
3
1
9
                              202

-------
     Adsorption of the carbamate pesticides  Sevin  and  Baygon
on granular activated carbon was investigated  by  El-Dib   et  al.
(193).  Passage of a 5 mg/£ solution  of  Baygon  through carbon
columns effected complete removal  for up  to  273 bed  volumes
of water when a contact time of 3.76  min  was allowed.   In
the case of Sevin, 1,800 bed volumes  were  passed  with  complete
removal under the same conditions.  Rapid  breakthrough of
the pesticides into the effluent occurred,  however,  as the
contact times were decreased to 1  or  0.5  min.

     According to reference 570, the  available  data  on
organophosphorus pesticide removal  indicates that  the  effi-
ciency of activated carbon ranges  from 50  to over  99 percent.
Stone and Company (537) cited laboratory-scale tests showing  that  Para-
thion was reduced from 10 to 2.5 mgA  using  20  mg/£  powdered
carbon; and from 11.4 to 0.05 mg/£  using  dual  granulated carbon
filters.  Malathion was reduced in  laboratory-scale  tests
from 2 to 0.25 mg/Ji with 10 mg/2 powdered  carbon.   Some  data
on removal  efficiencies of the  organic herbicides  were also
cited.  They report that over 99 percent  removal  of  2,4-5-T   and
2,4-D is possible.

     Robeck et al, (546) surveyed  the effectiveness of various water
treatment processes in pesticide removal.   Table   87  summarizes
their results using carbon in  both a  slurry form and in  beds.
          TABLE  87 .   SUMMARY  OF  CUMULATIVE PESTICIDE
                     REMOVAL  AT 10-ppb LOAD (546)
    Process
                            Pesticide Removed - Percent
               DDT    Lindane  Parathion  Dieldrin
                  2,4,5-T
                   Ester
                Endrin
Carbon:
  SIurry
     5 ppm             30
    10 ppm             55
    20 ppm             80
Bed 0.5 gpm/
    cu ft     > 99    > 99
> 99
> 99
> 99

> 99
75
85
92

99
  80
  90
  95

> 99
84
90
94
     In addition  to  activated  carbon,  other adsorbents such
as clays and synthetic  polymeric  adsorbents are capable of
removing biocidal  contaminants.   Morton and Sawyer (467) studied
the adsorption of  diazinon,  an organophosphorus pesticide,
onto attapulgite  clay.   Coarse-ground,  high-volatile matter
attapulgite was stirred  with contaminated water in laboratory
experiments.  At  least  50  percent of the diazinon in a 0.1
mg/£ solution was  removed  by the  clay  in a 10 percent clay
suspension.  An investigation  of  the use of the synthetic
polymer Amberlite  XAD-4  for  the  removal of various pesticides
                               203

-------
was cited by Stone and Company (537).  The pesticides examined
included lindane, B-BHC, aldrin, and dieldrin in tap water at
initial concentrations of 1  ppb each.  Consistent removals of
over 60 percent were reported.

     Schwartz (570) also studied the adsorption of selected
pesticides on activated carbon and mineral surfaces.  He found
that the clay minerals ilite, kaolinite, and montmori1lonite
suspended in dilute pesticide solutions adsorbed very little
2,4-D or isopropyl N-(3-chlorophenyl) carbamate (CIPC).
Adsorption of CIPC from aqueous solution with powdered activated
carbon, however, was extensive (>90 percent).

SYNTHETIC/ORGANIC CONTAMINANTS

     Adsorption is commonly  cited as a presently available
technology for removing particulate, colloidal, and soluble
organic contaminants from water.   Many of the organics  pre-
sent in water supplies - particularly the soluble and colloidal
organics - are of a refractory nature, i.e., they resist removal
by conventional methods.  A  number of these are potentially
toxic or carcinogenic and,  as a result, their detection, iden-
tification, and treatment in water is receiving increasing
attention.   These substances, even in small amounts, contri-
bute to taste and odor conditions and may pose a chronic
health hazard.   As has been  discussed, activated carbon  is
widely applied for taste and odor removal; however, its
effectiveness for removing  residual organics has just come
under study in recent years.  The delay has been caused  in
part by the lack of standard procedures for identifying  and
classifying the vast assortment of organics that occurs  in
trace quantities in water (262,455).  The delay is also  due
to the search for a gross organic parameter that can be  used
as a measure of organics.  The more common parameters used
include carbon chloroform extract (CCE), liquid extraction,
paper and gas chromatography, fluorescent spectroscopy,  and
radiation.

     Traditionally, carbon  life expectancy has been based on
the capability of the carbon to absorb tastes and odors.
But research has shown that  the life expectancy of carbon
to reduce carbon chloroform  extract or organic compounds is
somewhat less than that to  remove tastes and odors (442).
Medlar (442) suggested that  monitoring carbon chloroform
extract concentration  in carbon  filtered water would
provide a conservative estimate of filter performance,  but noted
that the CCE test may not encompass all the compounds that
should be considered.

     Carbon chloroform extract indicates the presence of stable
organic compounds in water.   The extract has an operational
definition and is a mixture  of organic compounds that can be

                               204

-------
adsorbed onto activated carbon and then desorbed with organic
solvents under specific controls.  Examples of substances mea-
sured with this method include substituted benzene compounds,
kerosene, polycyclic hydrocarbons, phenylether, and insec-
ticides.  The efficiency of activated carbon in reducing CCE
depends upon several factors including water temperature, ini-
tial amount of contaminant, and the molecular weight of the
contaminant (157).  Percentage removals must therefore be deter-
mined by laboratory testing.  Removals ranging from 50 to 99
percent were reported by David Volkert and Associates
(157).

     The adsorption of polycyclic (polynuclear) aromatic
hydrocarbons (PAH) from water by activated carbon was discussed
by Harrison et al. (284).  These compounds are potential
carcinogens under certain conditions.  Carbon  adsorption has
been shown to give 99 percent removal of PAH from water filtered
by prior seepage through river bank soil.

     Bis-ethers are synthetic organic compounds that may
occur in water associated with industrial discharges.  Stone and
Company (537) cited laboratory tests of activated carbon  treatment
in which isopropyl ether concentrations were reduced from
1,023 to 20 mg/£, butyl ether concentrations from 197 mq/i
to nil, and dichloroisopropyl ether concentrations from
1 ,008 mg/x, to nil.

     The treatment of dilute phenolic industrial  wastewater
was reviewed by Patterson  (506).  Adsorption onto activated  car-
bon has been employed to remove over  99 percent of the  phenol
present in process waters with initial concentrations  ranging
from 5,325 mg/a to 0.12 mg/£.  Final  phenol concentrations
ranged from 0.25 mg/£ for  treatment of a concentrated  solu-
tion to 0.001 mg/£ for treatment of weaker  solutions.

     Foaming agents such as  linear alkyl benzene  sul-
fonate in concentrations up  to 5 mg/a can  be removed  by  acti-
vated carbon with 90  to 100  percent efficiency according  to
evidence cited by David Volkert and Associates
(157).  Table 81  (Phillips  and  Shell,  515), which presents
data on activated carbon filtration at the  Colorado  Springs
pilot plant, shows  97  percent  removal of alkyl  benzene  sul-
fonate  (ABS).  Stander and  Funke  (610) reported  reduction  of
ABS from 4  to 0.7 mg/a at  the  Windhoek pilot plant.   Organic
acids are also reported  to  have  been  reduced from 1  to  0.4  mg/£.

      Morton and Sawyer  (467)  studied  the adsorption  of two
organic compounds  - diethylsti1bestrol  (DES), which is  a  hormone
and aflatoxin, which  is  a  natural  toxin  produced  by  fungi  -
onto  attapulgite  clay.   Attapulgite  is a magnesium  aluminum
silicate clay that exhibits  a  high  degree of adsorption  for
                               205

-------
 low-weight organic molecules.  Coarse-ground, high-volatile-
 matter attapulgite was contacted with contaminated water in
 laboratory experiments.   DES at a concentration of 5 ppb was
 decreased 68 and 76 percent by contacting with 1.1 and 10
 percent (fay weight) clay suspensions, while in a 50 ppb
 solution the removals were 68 and 89 percent, respectively.
 More than 98 percent of  the aflatoxin at concentrations of
 0.5 ppb and 5.0 ppb was  removed by both 1.1 and 10 percent
 clay suspensions.   The results of column percolation studies
 through granular low-volatile-matter clay are presented in
 Table 88.
         TABLE  88.   REMOVAL OF ORGANICS BY PERCOLATION
                 WITH GRANULAR, LVM ATTAPULGITE

 Ratio of percolate                  Recoveries in Effluent
 volume to bed volume              Slow rate*       Fast rate1"
Initial Concentration
2.5
5.0
10.8
12.6
52 ppb
ND}
ND
ND
— —
48 ppb
ND
1

2
     Initial Concentration           17 ppb           17 ppb
        2.5                       ND               ND
        5.0                       ND               ND
       10.8                       ND
       12.6	--	    ND	

 *  960  gal/ton  clay/hour.
 t  2,880 gal/ton  clay/hour.
 £  ND =  not detectable.


     Stone and Company (537) cited  data concerning the  treatment
of polychlorinated biphenyls (PCB's) by adsorption onto  clay
minerals and Amberlite polymeric adsorbents.   In  laboratory
tests,  Amberlite XAD-4 removed up to 76 percent of the  PCB
present in solutions.  Several  clay minerals demonstrated PCB
removal capability in laboratory tests:  illite - 60 percent,
montmorillonite - 40 percent, and kaolinite -  40  percent.
Kinoshita and Sunata (352) evaluated the adsorption of  PCB onto
powdered activated carbon in a  jar  test and found that  the
initial concentration of 100 ppb PCB was reduced  to 10  ppb in the
product water.
                               206

-------
     The Amber-lite  adsorbents  represent a new technology  for
adsorbing organic molecules  from water.  They are used  spe-
cifically for adsorbing  aromatic and aliphatic compounds.
According to Simpson  (589),  small molecules such as  phenol
are effectively  adsorbed by  Amberlite XAD-4, while for  a
larger molecule  such  as  an alkylbenzene sulfonate, Amberlite
XAD-2 has a much  higher  adsorptive capacity.  Phenol  is a
model aromatic,  low-molecular  weight compound that is  con-
sidered  to be highly  objectionable, as are  some  of the  chlori-
nated phenol products.   Using  the XAD-4 adsorbent, up  to  40
bed volumes of  a  500  ppm water solution of  phenol were  treated
with less than  10  percent leakage at a flow rate of  0.5 gal/fW
min.  At a higher  flow  rate  of 2.0 gal/ft3/min,  20 bed  volumes
were treated with  less  than  10 percent leakage.   It  was further
found that the  adsorptive capacity was higher for  chlorinated
phenols  than for simple  phenol.  Simpson  (589)  cited a labora-
tory study  in which the  removal  efficiency  of Amberlite XAD-2
for  a list  of organics  at flow rates of  1.25  gpm/cu  ft were
determined.  The results are presented  in  Table 89.   Non-
ionic compounds were  removed with  100  percent efficiency while
ionized  compounds were  less effectively  removed.

      In  the  nationwide  study of  water  supplies  and water treat-
ment  facilities by Symons et al.  (632)>  it was  concluded that
both  powdered  and granular activated  carbon treatment  signi-
ficantly reduced the trace concentrations  of  total  trihalo-
methane  in  the  product water.


        TABLE   89.*  ADSORPTION  OF ORGANIC COMPOUNDS ONTO
            AMBERLITE XAD-2 POLYMERIC  ADSORBENT  (589)

                                                       Retention
 1.  Aliphatics                      Influent    Effluent    Efficiency, %

    a) alcohol: n hexanol            200 ppm     30 ppm       85
    b) ester: ethyl butyrate         100         0          100
    c) ketone: methylisobutylketone   100         0          100

 2.  Aromatics

    Benzene                        100         0          100
    Benzene sulfonic acid              3.0       2.1          31
    p-toluene sulfonic acid            9.0       6.9         23
    Benzoic acid                      1.0       0.8         23
    Benzoic acid  (pH 3.2)              1.0       0          100
    Phenol                           0.4       0.22        45
    Phenol (Amberlite XAD-7)           0.4       0.06        86
    0-Cresol                         0.3       0           100
    2, 4-dimethyl  phenol               0.4       0           100
    p-nitrophenol                     0.2       0           100
    2-methylphenol                    0.3       0           100


                                 207

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TABLE  89. (continued)
2.  Aromatics  (continued)
Influent    Effluent
  Retention
Efficiency,
4, 6-dinitro-2-aminophenol
Phenylenediamine
Aniline (Amberlite XAD-7)
Naphthalene
2-hydroxy-3 naphthoic acid
0.4
0.9
4.0
0.05
0.6
0.22
0.02
0
0
0.37
43
98
100
100
39
BIOLOGICAL CONTAMINANTS

     The limited efficiency of activated carbon  in  removing
viruses from wastewater was discussed  in the advanced  waste-
water treatment section of this report.  Results  show  that
activated carbon is inefficient in removing viruses  from
drinking water.  Oza and Chaudhuri (498 ) suggested  that the
inefficiency may be due to the exclusion of viruses  from  the
micropores of activated carbon because  of  their  size.
Coal adsorption of a bacterial virus was investigated,
and results indicated that coal may be  a more effective
adsorbent than activated carbon.  Morton and Sawyer  (467 )
demonstrated that attapulgite clay also has the  capacity  to
adsorb polio virus from water.  Aqueous virus-clay  suspensions
were shaken for 1 min and then filtered.   High-volatile-
matter clay completely removed virus infectivity  from  a
20 percent clay suspension with an initial virus  concentration
of 16 million infectious particles per  rru.  However, reducing
the contact time from 30 to 5 min or the clay concentration
from 20 to 5 percent resulted in incomplete removal.
                               208

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             ADVANCED  WATER  TREATMENT:   ION  EXCHANGE
     Ion exchange has  its  greatest current application  in
industrial  and small-scale potable water supply operations.   The
most common use of ion exchange is for removal  of hardness
(calcium and magnesium cations) from municipal, industrial,
household,  and laboratory  water supplies.   It is particularly
suited for  desalting brackish water, pretreating water  that  must
be almost completely demineral iz'ed for industrial use,  and
remo.ving metals from industrial metal  plating rinse wastewaters.

     No one ion exchange resin  is capable of removing all ionic
contaminants.   Various resins,  depending upon their chemical
nature, show preferential  selectivity for specific ions.
Table 90  presents data on ion  selectivity for various  types of
exchange resins (506).


_ TABLE  90.  ION EXCHANGE RESINS SELECTIVITY (506) _

_ Resin _ Resin Selectivity* _

Strong-acid cation         Li+, H+, Na+, NH4+, K+, Rb+, Cs+,
  (Sulfonic)               Mg+2, Zn+2, Cu + 2, Ca+2, Pb + 2
Weak-acid cation           Na+  K+, Mg+2, Ca+2,
  (Carboxylic)             Cu+2, H+
Strong-base anion          F", OH', ^04-, HC03-, Cl~, N02',
  (Type I)                 HS03-, CM- ,  Br~ , N03-f HS04-, I~
Strong-base anion          F~, H2P04~, OH~,
  (Type II)                C1-, N02-, HS03-, CN~,
                           Br~, N03-, HS04~, I-
Weak-base anion            F", Cl~, Br", I~, P04-3,
                           N03-, CrQ4-2, S04-2, OH"
increasing selectivity left to right.


     The more strongly a resin adsorbs a particular ion, the
more complete the ion removal.  However, a high affinity
between a particular resin and a specific ion also means greater
difficulty in regenerating the resin;  that is, it is more

                               209

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difficult to release the adsorbed ions to make the resin reuse-
able.  As a result, regeneration of an effective resin is
seldom carried to completion, and the operational capacity of an
ion exchange resin may be reduced to 50 to 60 percent of theoret-
ical ca paci ty.

     Ion exchange processes are very sensitive to both clogging
and fouling.  An ion exchange resin bed is a good filter;
therefore, suspended solids in water will clog the bed.   Fouling
results when the resin adsorbs materials which, because of their
adsorption or absorption into the resin pores, cannot be removed
in the regeneration step.  Fouling often results from the
irreversible sorption of high molecular weight organic acids.

     The nonselective nature of most exchange resins is a
drawback when attempting to remove a low-level contaminant from
water.  The simultaneous removal of other nontarget ions rapidly
increases the cost of using the process.  More selective resins
are currently becoming available (Koerts, 359).

     In the past, application of ion exchange processes was
confined to the removal of ionic contaminants.  Recently,
however, some ion exchangers have been developed that can remove
nonionic species, e.g., A1203, Fep03, H2Si03, etc.  Resinous
adsorbents are also available that are particularly suited for
removing organic compounds - including biocidal and synthetic/
organic contaminants - from water.  While often used in conjunc-
tion with true ion exchange processes, the mechanism of organic
removal is actually adsorption; therefore, the resinous or
polymeric adsorbents (as they are called) are discussed in the
carbon adsorption section of this report.  The literature
utilized during this review on the removal of various contami-
nants by ion exchange methods is indicated in Table  91.

WATER QUALITY PARAMETERS

     Reduction of total dissolved solids may be an important
application of the ion exchange process when reclaimed waste-
water for potable reuse is the objective of treatment.  High
total dissolved solids concentrations, from 500 to over 1,000
mg/£, are found in wastewaters.  Approximately 300 mg/£ of total
dissolved solids is generally considered the increment added
during one cycle of domestic use of a water supply.  Ion
exchange treatment of water and wastewater for removal of
dissolved solids is most successful after prior treatment using
both conventional and advanced techniques has taken place.  This
prevents clogging and fouling of the exchange resins.

     Ion exchange is technically capable of producing a water
with only 0.055 mi cromhos ,(jjmhos) of specific conductance.  One
micromho will  normally indicate a dissolved solids concentration
of 0.5 to 0.6 mg/£.  However, water of such purity is rarely

                               210

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   TABLE 91.   LITERATURE  REVIEWED  PERTAINING  TO  ION  EXCHANGE

Contaminant	Reference  Number	
Water Quality
Parameters
  Ammonia              101,  505,  506,  524
  Chlorides            157,  505,  506,  524
  Color                157
  Cyanides             157,  506
  Fluorides            157,  506
  Hardness             505
  Nitrates             63, 90,  101,  119,  157, 267,  297
  Phosphates           63, 119
  Sodium               119,  157,  505
  Sulfates             119,  157,  505
  Total dissolved      63, 119, 505, 506
  solids
Elemental Contaminants
  Arsenic              99, 506, 576
  Barium               506
  Boron                506
  Cadmium              506
  Chromium             506
  Copper               359,  506
  Iron                 12, 506
  Manganese            12, 506
  Mercury              359,  506
  Nickel	506	
                               211

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TABLE 91  (continued)
Contaminant	      Reference Number
  Selenium             506
  Zinc                 359, 506
                              212

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required, and the costs  to  achieve such purity would be pro-
hibitive.  Complete  demineralization of municipal water supplies
is unwarranted and may  even have adverse consequences, as the
body requires certain  trace concentrations of many mineral's.

     The EPA and  the LA  County Sanitation Districts jointly
funded an advanced wastewater  treatment facility in Pomona,
California.  The  results  of the ongoing tests have been compre-
hensively reported by  Parkhurst (505) and Chen (119).  The  ion
exchange system,  which  was  proven to be of economic and technical
feasibility, effectively  reduced the total dissolved solids  by
90 percent.  The  treatment  involved passage first through a
primary cation column  and an anion column, then through a
secondary cation  column  and a  secondary anion column.  A series
of 80 complete operating  cycles including exchange, backwashing,
and regeneration  was completed at a 2.5-gpm flow rate.  The
total dissolved solids  concentrations of the feed and  product
waters averaged 610  mg/a  and 72 mg/£, indicating an 89 percent
average reduction.   A  complete listing of the various  consti-
tuents at successive stages of the demineralization sequence  is
presented in Table   92  (505).
         TABLE  92.  AVERAGE WATER QUALITY CHARACTERISTICS OF THE
      ION EXCHANGE PILOT PLANT UNDER TYPICAL OPERATING CONDITIONS (505)*

Calcium
Magnesium
Sodium
Potassium
Ammonia, as N
Sulfate
Nitrate, as N
Chloride
Orthophosphate,
as ?OA
Total alkalinity,
as CaCOo
PH
Conductivity
Silica, as Si02
Carbon
Column
Effluent
(feed)
53+
17
126
14
20
72
2.9
135

27


7.4
10
23
Primary
Cation
Effluent
2.0
0.59
61
7.3
9.6
72
2.8
132

27


2.7
9.7

Primary
Anion
Effluent
1.7
0.56
59
7.1
9.2
3.6
1.6
84

15

51
5.7
6.8

Secondary
Cation
Effluent
1.1
0.38
16
1.9
4.0
3.6
1.5
83

14


2.8
5.5

Secondary
Anion
Effluent
(product)
0.60
0.00
15
1.9
3.8
1.3
0.35
14

0.25

39
5.8
3.7
23
*Data taken from May 1968 through December 1968.
tAll constituents in mg/£ except:  (1) pH and (2) conductivity (ymhos/cm).
                               213

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     All of the major anions and cations were removed to a
considerable degree except silica.   Silica removal  can be
accomplished, however, with highly basic anion resins (Betz,
 63). "Calcium and magnesium, the cations responsible for water
hardness, are almost completely removed in the primary cation
exchanger; but only about half of the sodium, potassium, and
ammonium ions are removed in this column.  The secondary cation
exchanger, however, efficiently removed the majority of the
remaining ions.  Similarly, the primary anion exchanger removed
most of the sulfate ions, while the nitrate, chloride, and
orthophosphate ions were partially removed by both  the primary
and secondary stages.

     David Volkert and Associates (157) cited evidence
that the sodium and fluoride concentrations of water can be
reduced by 95 percent using ion exchange.  It reported that
chloride, sulfate, and nitrate can be reduced by as much as 95
percent, depending on the degree to which the exchange resin  can
be regenerated.

     The application of ion exchange to nitrate reduction of
reclaimed wastewaters may be particularly important, as these
waters frequently may contain nitrate concentrations in excess
of the 10 mg/£ limit set by the U.S. Environmental  Protection
Agency as an interim primary drinking water standard.  The use
of ion exchange resins for the removal  of ammonium  and nitrate
ions has been discussed in the adsorption section of this report,
Few specific exchange resins are available for removal of the
nitrate ion from wastewater; ammonium ion removal with certain
specific zeolite  resins can be quite effective.  In wastewater
treatment, significant nitrogen removal may be effected by
removing ammonia with ion exchange; in water purification treat-
ment, nitrate is often the most significant form of nitrogen.
Strong nonspecific anion exchange resins have been  applied to
the removal of nitrates from drinking water; but because the
resins are nonspecific, competition from sulfides,  chlorides,
silicates, and phosphates limits the target removal of nitrates.

     This problem of competing ions may be significant when
considering potable reuse, since reclaimed wastewaters that are
high in nitrates are also likely to be high in these anions.
The caking and clogging problems caused by iron, turbidity, and
colloidal matter are also significant.   In other words, ion
exchange technology for nitrate removal is still developing.   A
successful application of the available technology  has taken
place at Long Island, New York (267,297).  A few years ago, Long
Island communities began experiencing rising nitrate levels in
their drinking water supply source.  Drinking water was obtained
from groundwater wells that had been contaminated with nitrates
from septic tanks and cesspools.  An ion exchange process
originally developed to demineralize industrial process water
was adapted in a prototype ion exchange plant; it reduced the

                               214

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nitrate content of several  thousand gallons  of the  Long  Island
water from 22 ppm to 0.5 ppm nitrate.   A plant was  then  built
that successfully provided  ion exchange treatment for the  Long
Island well water under the constant flow and pressure require-
ments of a municipal water  system.   However, the well water was
of relatively low total dissolved solids, and it is uncertain
how this process would perform on waters of  poorer  quality.

     A water quality parameter that is of interest  in potable
water treatment is color.   According to David Volkert and
Associates (157), ion exchange resins  have been  developed
that will completely remove color-causing organic dye wastes,
humates, and lignates.

ELEMENTAL CONTAMINANTS

     Ion exchange techniques have been applied to the treatment
of industrial process water containing trace metals for several
years.  Application of these techniques to drinking waters con-
taining trace concentrations of these metals is analogous.  In
a review of the literature, David Volkert and Associates
(157) found that several trace elements can  be removed from
water to a level of 95 percent.  Table  93 lists these elements
and gives the maximum concentrations that can be reduced to
1974 Standards and Guidelines  in a single pass through an  ion
exchange process (157).  Water containing concentrations of a
particular contaminant higher  than the maximum listed in the
table can be either passed through a series  of ion exchange
columns with different types of resins, or pretreated by a
method  such as lime coagulation to precipitate the major amount
of the  metal present.

     Calmon  (99  ) noted that anion exchange  treatment can  be
used to remove residual arsenic after  lime coagulation  is  used
to precipitate the major amount present.  Both weak  and strong-
base ion exchange resins appear effective in  removing arsenate
and arsenite from drinking water (Patterson,  506).   Calmon  ( 99)
treating an arsenate water containing  68  mg/a arsenic at pH
6.95 with a weak-base  anion exchange resin  (lonac  A-260),
reported 82 to 100  percent removal.  Medium  and  strong-base
resins  (lonac A-300, A-540, and A-550) were  less effective.

     Again  using  the  weak-base anion exchange resin  (lonac
A-260),  Shen  (576)  treated water containing  106  mg/£  of
arsenic.  Only 20.7  percent of the arsenic was  removed.  When
well waters with naturally high arsenic  levels were  treated,
essentially  100  percent removal was achieved.  The disparity of
the results was  not  explained.

     Bone char and  activated  alumina readily remove  arsenic via
an ion  exchange  mechanism.  Arsenic sorption on  bone char
results  in  an  irreversible change  in the  chemical  structure of


                               215

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             TABLE  93.  REMOVAL OF TRACE ELEMENTAL
                   CONTAMINANTS FROM WATER BY
                       ION EXCHANGE (157)
                                       Maximum*
             Contaminant  % Removal  Concentration
Arsenic
Barium
Cadmium
Chromium
Copper
Cyanides
Lead
Iron
Manganese
Mercury
Selenium
Si 1 ver
Zinc
95
95
95
95
95
95
95
95
95
95
95
95
95
2.0 mg/
20.0
0.2
1. 0 mg/
20.0
4.0
0.1
6.0
0.1
0.04
0.2
0.1
100
A


£









*Maximum concentration in raw water,  which can be reduced to
 1974 Standards and Guidelines in a single pass through process,
 If raw water concentrations are higher,  then combination or
 duplication of processes or other processes must be considered,
                              216

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the char.   Consequently,  exhausted  bone  char  must  be  discarded;
it cannot  be regenerated.   Activated  alumina  is  regenerable.

     Effective removal  of barium by ion  exchange has  been
reported.   Patterson (506)  cited a  98.5  percent  reduction  of
barium from 11.7 to 0.17  mg/j, in a  full-scale ion  exchange
groundwater softening plant in which  a general  nonspecific water
softening  resin was used.

     .According to Patterson (506),  ion exchange  is a  common
method for recovery of cadmium from industrial  wastewaters, and
many exchange resins are  available  with  high  specificity for
the metal.  To meet stringent effluent standards,  some industries
are using  ion exchange rather than  cheaper but  less effective
methods to treat chromate and chromic acid waters.  With proper
pH adjustment, chromate is  removed  even  in the  presence of high
concentrations of sulfate and chloride (506).  Reduction of
hexavalent chromium to 0.023 mg/a in  a metal  finishing waste-
water has  been reported (506).  Cation exchange  can be applied
to remove  trivalent chromium, and anion  exchange can be employed
to remove  chromate and dichromate (506).

     Ion exchange is capable of achieving very high levels of
copper removal.  Reduction  of 1.02  mg/£  copper to less than 0.03
rng/5, has been reported.  A selective  ion exchange resin (Amber-
lite IR 120) reduced the  copper concentration of an industrial
copper plating rinse solution from  45 mg/a to an undetectable
amount (506).  Koerts (359) found that ion exchange can remove
copper and zinc from industrial waters to produce effluents
containing as little as 0.04 mg/s, of copper and 0.1 mg/£ of
zinc.

     Removal of several metals, such as  iron, manganese, lead,
copper, and nickel can be accomplished with  ion exchange,  but
the processes involve low pH or anaerobic water streams, which
make them normally unsuitable for municipal water treatment.
This technology, however, may be expected to develop as more
attention  is given to the application of ion exchange for  the
purification of reclaimed municipal wastewaters.

     Ion exchange treatment of inorganic mercury-bearing waters
appears to be capable of furnishing an effluent with 1 to  5 ppb
inorganic  mercury.  Table 94  from  Patterson (506) reviews the
experience with ion exchange treatment for inorganic mercury.
Effluent values in the ppb range are  indicated.   Preliminary
tests have indicated that cation and  anion exchange resins in
series can remove 98 percent of both  inorganic and organic
mercury forms.  Akzo Chemie has developed a special resin  for
mercury, which produces effluent levels  below 5 ppb mercury (359)
                               217

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                  TABLE  94.   ION EXCHANGE TREATMENT
                      FOR INORGANIC MERCURY (506)
Resin Type
Mtylon-T
Anion*
Macroreticular
Anion*
Osaka IE*
Osaka MR*
ActiveX
Ajinomoto


Billingsfors
Treatment
PH
5-6
7
na
na
"acidic"
na
na
1.5
6.0
11.0
6.5
Mercury (ygA)
Initial Final
5,000-25,000 1
850 2.5
10,000 <10
470 30
3,000-10,000 100-150
100-150 2-5
10 <5
60 5
87 3
1 ,800 990
35 1
Additional
Treatment
•• •
--
--
--
Prefilter
Osaka IE Resin
--
--
--
--
--
Percent
Removal
100
99.7
100
94
98
98
50
92
97
45
97
*Mercury removed as mercuric chloride complex, HgCl
                                             (2-x)
     Patterson (506) presented  evidence  that  cation  plus anion
exchange applied to secondary wastewater effluent  can  remove
selenium to a level of 99.7 percent.   He also cited  an example
of 85 percent removal of silver  from  an  extremely  dilute
secondary sewage effluent by cation exchange,  and  91.7 percent
removal  by combined cation-anion  exchange.

     Calmon (100) discussed the  use of ion-exchange  for trace
heavy metal removal.  As part of  his  paper,  he listed  the
specific resins that can be used  to remove  various heavy metals
These are as follows:
     Element

     Arsenic (3+)
     Beryl 1ium
     Bismuth
     Boron

     Cesium
     Cobalt
     Copper
     Germanium
     Gold
Polar Group

F1 u o r o n e
Phosphonic diallyl phosphate
Pyrogallol
N-methyl glucamine, tris  hydroxymethyl
   amino methane
Phenolic OH +  sulfonic groups
M-phenylene diamine, 8-hydroxyquinoline
Phenolic OH +  phosphonic  groups,
   8-hydroxy quinoline
   m-phenylene diamine
      imino diace tic acid
   a 1g i n i c acid
Phorone
Pyridinium, thiourea
                               218

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     Element           Polar  Group

     Iron              Alginic  acid
                         m-phenylene diamine
                         hydroxamic  acid
                         phosphonous
                         phorone
                         chlorophyll
                         haemin deriv.
     Lead              Pyragallol,  phosphoric
     Mercury           Thiourea, thiol,  iminodiacetic acid,
                         mercapto  resins
     Nickel            Alginic  acid,  dimethylglyoxime
     Potassium        Dipicrylamine
     Strontium        Phosphorous
     Titanium         Chromotropic  acid
     Uranium           Pyridinium,  phosphorous ester
     Zinc              Anthranilic
     Zirconium        Phosphate ester


He also discussed the various  types  of  exchangers, dosages,
operating  problems, etc., that can  be anticipated for removal
of each metal.

BIOCIDAL CONTAMINANTS

     Ion exchange units are not specifically designed to remove
biocidal contaminants.  However, some incidental removal of
these pesticides, insecticides, and  herbicides may occur due to
adsorption on the resin material.   This phenomenon will occur
until the  adsorptive capacity of the resin  is exhausted.

SYNTHETIC/ORGANIC CONTAMINANTS

     Because many of the synthetic/organic  contaminants have
chemical and physical properties that are similar to the
biocidal contaminants, the same considerations apply here as in
the biocidal  section.

BIOLOGICAL CONTAMINANTS

     Since the primary removal mechanism of  ion exchange is
based on particle charge properties, any removal of the
biological contaminants will be incidental.  Any removal that
does occur will probably be due to  mechanical filtration.
                                219

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           ADVANCED WATER TREATMENT:  REVERSE OSMOSIS
INTRODUCTION

     For readers unfamiliar with the osmotic membrane process,
one can picture these membranes as thin sheet filter materials.
Initial investigators thought that the membranes acted as
strainer-type materials with such small pore sizes that most
ionic and biological  molecules were too large to pass through.
Recent studies with electron microscopes have shown that
removals are controlled by molecular diffusion through the
membrane and that salts and other impurities diffuse much more
slowly than water (652).  The differential  pressure to provide
a driving force through the membrane is supplied by pumps.  The
discarded flow of concentrated contaminants is continuous,
and its volume normally equals from 5 to 30 percent of the
volume of the process influent volume.  Membrane fouling by
suspended solids, organic slimes, and precipitates is a problem
unless substantial  pretreatment of the influent water is pro-
vided.  Therefore,  reverse osmosis (RO) is normally located as the
last unit process in  the water treatment chain.

     Very little actual operating data are  available regarding
the use of reverse  osmosis for treatment of municipal
water supplies, because the quality provided by reverse osmosis
systems has not as  yet been required.  Even in areas of high
TDS that could benefit from RO treatment, the cost of this
unit process has been prohibitive.  There has, however, been
a substantial amount  of research conducted  on the use of RO
for polishing highly  treated wastewaters.  This research,
though,   primarily  focuses on the removal of selected contami-
nants from solution in laboratory and pilot scale projects.
Since these are similar in many respects to raw water supplies,
performance is often  analogous to water treatment situations.

     Reverse osmosis  may become more important in the future
as both a tertiary  wastewater and raw water supply treatment
process, because of its capability to remove a high percentage
of all types of general, elemental, and biological contaminants
as well  as many synthetic/organic and biocidal constituents.
With the recent concern over even very small concentrations of
heavy metals, residual organics, and toxic  compounds in water
supplies, RO with its >99 percent removal efficiency may see
increased usage, albeit at a high cost.


                               220

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     Aqueous solutions of two or more solutes reacting with a
membrane may give product flux and solute retentions that are
quite different from those predicted from the behavior of
solutions of the individual salutes.  This results from inter-
actions between solutes, their products, and the membrane.
Improved retentions of solutes have been observed when mixed in
partially treated wastewaters, thus increasing the attractiveness
of wastewater RO treatment for reuse (191).   Improved retentions
are thought to be due to synergistic effects among the high
molecular weighted components.

     Various types of membrane systems have been tested on a
variety of wastewater effluents from primary to highly
treated tertiary.  Laboratory tests have also been conducted
on the removal of many synthetic/organic chemicals and bio-
cidal compounds.  The RO process does not destroy any of the
input contaminants, but only  separates them into two streams,
with the waste stream containing the rejected materials.
Depending upon the feed conditions  and the desired objectives,
the product water volume can  range  up to 95 percent of the
total influent, with the remainder  representing the discarded
flow.  The characteristics of RO membranes can be controlled
within a wide range by controlling  the manufacturing  variables.
In general, as one improves the contaminant removal efficiencies,
the flux per unit area decreases.   This type of trade-off
implies that the systems can  be optimally designed  to achieve
the desired objectives.

     For this study, the literature reviewed was  oriented
towards tertiary wastewater applications as well  as  laboratory
and pilot scale  tests of osmotic membranes.  The  literature
excluded the extensive basic  research on osmotic  membranes
for other applications  (e.g., industrial wastewater  treatment).
The very extensive patent  literature on the different types
of membranes, designs,  and manufacturing processes  was  also
excluded.  Table 95 provides  a  summary  of the current literature
pertaining  to  the  performance of  reverse osmosis  units.

WATER  QUALITY  PARAMETERS

     RO  systems  are not  commonly  used specifically  for  general
contaminant removal from water supplies (with the exception of TDS), as  these
constituents  can  be  sufficiently  removed  by  other less  expen-
sive treatment  units.   However,  there were  quite  a  few  references
that noted  the  performance of RO  on general  contaminant  removal
from wastewaters  as  shown  in  Table  95.   The  performance  of RO
systems  in  terms  of  percent  removal is  excellent  (90  to  99+
percent)  for  all  general  contaminants except  for  low molecular
components  of  BOD,  or  COD, and
                               221

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   TABLE  95.   LITERATURE  REVIEWED  PERTAINING  TO  REVERSE  OSMOSIS
 Contaminant
           Reference  Number
 Water Quality Parameters
  ABS
  NH4
  BOD
  COD

  Chlorides
  CN
  Fluorides
  Hardness
  N0
  so4
  TDS

Elemental Contaminants
  Aluminum
  Arsenic
  Barium
  Boron
  Cadmium
  Chromium
  Copper
  Iron
 46,  281,  286,  449,  593
 120,  148,  149,  182,  281,  294,  449,  593
 148,  286
 120,  148,  149,  182,  189,  371,  449,  593,
 615
 120,  148,  149,  294,  449,  593,  671
 294,  671
 148,  294,  671
 286,  294,  449
 140,  148,  182,  281,  286,  294,  593
 120,  148,  149,  182,  281,  286,  294,  449,
 593
 120,  148,  149,  294,  449,  593
 120,  148,  149,  182,  281,  286,  371,  449,
 593

 148,  294
 157
 157
 148,  157, 294, 671
 157, 294, 615
148, 157, 294, 615, 671
157, 294, 615, 671
157. 294, 449,. 593, 615
                               222

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TABLE 95 (continued)
Contaminant	Reference  Number	
  Lead                 615
  Magnesium            120,  148,  149,  294,  449,  578, 593, 671
  Mercury              157
  Nickel               615,  671
  Potassium            148,  149,  294,  449,  578,  593
  Selenium             157
  Silver               157,  615
  Zinc                 157,  615
Biocidal  Contaminants
  DDT                  46,  126
  ODD                  46,  126
  Aldrin               126
  Organophosphorus     126
  insecticide
  Chlorinated          126
  hydrocarbons
  D i e1d r i n             126
  Herbicides           126
  Lindane              46,  126
  Pesticides           126,  191
Synthetic/Organic
 Contaminants
  Misc. organics       46,  148,  189, 281
Biological  Contaminants
  Bacteria             148,  294
  Virus                148
                                223

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     Several references discussed the removal of ABS from
solution.  The presence of highly nonbiodegradable alkyl
benzene sulfonate (ABS) even in concentrations of only 1 mg/l
can produce undesirable frothing and foams although health
implications do not appear significant.  Hauck and Sourirajan
(286) reported removals of 99+ percent with a high feed con-
centration of 300 mg/l .  Merten and Bray (449) and an EPA
study (593) both reported ABS rejection of about 98 percent
with a variety of membranes.  Bennett et al. (46 ) tested RO
performance on a vast array of organics.  They showed ABS
removals of 90 percent at a 14 gpd/ft^ flux.

     Many studies were conducted that included ammonia removal
(see Table 95  ).  Reported removals  ranged from 60 to 97
percent.  Since ammonia concentrations are not generally
of significance in water supplies and NH is readily oxidized
in treatment processes, further discussion is not necessary
here.

     Hauck and Sourirajan  (286)  studied the performance of RO on
hard water and on wastewater.  The average BOD removal from
secondary effluent was 85.8 and 80.8 percent at 1,000 and 500
psig, respectively.   Cruver (148) reported secondary
effluent BOD rejections varying from 81 to 94 percent with a
cellulose acetate membrane.

     COD removal is  studied more frequently than BOD removal
in regard to RO performance, because many of the nonbiodegradable
constituents of COD  can be effectively removed by RO.  A review
of all  nine references reporting on COD removal  shows a removal
range of 90 to 99+ percent with an average of about 95 percent.
As a typical example, one of the larger scale pilot programs
performed at Hemet and Pomona, California (615), found that
RO provided very good removals of trace organics.  The COD of
secondary effluent was reduced from 39 mg/l to 1 mg/£ at
Pomona,  while  activated carbon effluent COD was reduced from
11.4 mg/l to 0.3-1.0 mg/£  .  Similar removals were reported
from the RO pilot plant at Hemet.  It was found that although
RO was  capable of greatly reducing effluent COD concentrations,
the costs for  full-scale operation are very high.

     Chloride  is readily removed by RO.  Many studies have
evaluated this constituent with removals ranging from 85 to
97 percent (120, 148,  149,  294,  449,  593, 671).

     Two references  included CN removal in research efforts
(294,  671).  Hindin  and Bennett (294) found that CN removals
ranged  from 79 to 85 percent at a flux of about 18 gpd/ft .  A
summary  report (671) listed typical  CN removal  at about 90
percent.
                              224

-------
     A study by  Cruver  (148)  reviewed  RO  performance  in  removing
various contaminants.   It was found  that  fluoride  removals
ranged from 88 to 98  percent  using selective cellulose  acetate
membranes.   Hindin and  Bennett (294)  and  reference 671  reported
similar results.

     RO units are highly efficient at removing hardness  (Ca
and Mn++)  from water supplies.  Hauck and  Sourirajan (286)
summarized the effects  of RO  treatment of hard-water supplies
in five cities and formal removals ranging from 96 to 99.9
percent as CaCOs.  Operating  pressure was 1,000 psig with a 90
percent product recovery.  Performance was directly related to
flux, with the higher removals achieved at lower flowrates.
Merten and Bray  (449) also reported removals at roughly 99 per-
cent  for the more efficient membranes they analyzed.

     The reviewed data indicates  that nitrate nitrogen is one
of the most difficult compounds for RO processes to remove
(593).  Hauck and Sourirajan   (286) reported NO^-N  removals
ranging from 50  to 60 percent.  Extensive pilot testing by
the EPA at  Pomona, California, showed NOo-N removals of 54 per-
cent  over  the first 9,475 hours of operation  (120).  The five
other  references  showed  similar poor  removals ranging from
51 to  86 percent  and averaging around 60  percent.

      Both  P04= and S04=,  on  the other hand, were  very readily
removed by RO processes.  All references  reviewed  showed
removals of 94 percent  or better, some up to  99.9  percent.

      The  primary water  treatment  use  of  RO  units  is  to  reduce
 the  TDS concentrations  of highly  mineralized  waters.   One  full-
 scale example  of this  is the Orange  County  Water  Districts
Water Factory 21 (371)  where 5mgd of  highly treated  effluent
 is  given RO  treatment  prior  to  recharge  of  potable aquifers.
 Results  from the operation  to date  show  a 90  to 95 percent
 TDS  removal at  90 percent feed  recovery.   Results from other
 references using various membranes,  pressures,  and fluxes
 showed that average  TDS removals  were about 91  percent and
 ranged from 89  to 99 percent.  Removals  can be controlled by
 membrane  selection and adjustment of flux.   Studies of pilot
 RO systems at Pomona (120)  showed TOC removals of 86 percent
 when using primary effluent  on the  feed.

      The major problem areas associated  with general contaminant
 removal  are fouling, short  membrane l*fe, and associated
 engineering problems.    If the membrane life and flux rate prob-
 lems are  solved, the RO membrane technology may become applicable
 to wastewater treatment where some sort  of reuse  is desirable
 and salt  content would  restrict  reuse.   At present, the tubular
 type membrane systems appear to  be more  applicable to sanitary
 wastewaters  due to the  lower fouling and easier  cleaning


                               225

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 inherent in this type of design.  This advantage may not be as
 significant in potable water treatment.

 ELEMENTAL CONTAMINANTS

      A good deal of available literature on RO membranes
 deals with removal  of elemental  contaminants.  RO systems can
 be designed to remove almost any elemental contaminant existing
 in either an ionic  form or colloidal  form in water.  Generally,
 multivalent ions (Fe+3, Cu*"1", Zn++, S0«)are rejected more
 effectively than monovalent ions (B+, NOo).  As previously
 mentioned, the percentage removal will depend upon the specific
 membrane and manufacturing procedures.  Most references provide
 a lengthy list of contaminant removals.  It would be redundant
 to discuss each of  them here.  References 154, 294, and 615
 provide typical summaries of the performance of reverse osmosis
 units in removing elemental contaminants.  Results are shown
 in Table  96.   AS shown, RO is generally very effective.


             TABLE   96.   REVERSE  OSMOSIS  REMOVAL  OF
	ELEMENTAL  CONTAMINANTS  (REF.  154.  294,  615)	

                        Percent Removal  (Single  Pass)

 Contaminant       Reference  154   Reference  294   Reference  615
Aluminum
Arseni c
Barium
Boron
Cadmium
Chromium
Fluorides
Copper
Lead
Iron
Manganese
Mercury
Nickel
Selenium
Si Tver
Zinc
-
90-95
90-95
-
90-98
90-97
90-97
90-97
90-99
90-99
90-99
90-97
- *
90-97
90-97
90-99
97
-
-i
50
68-70
93-98
88-98
82-96
-
95-98
-
-
-
-
,
-
-
-
-
-
66-98
82-98
-
99
99
94-99
-
-
98-99
-
96
97
                              226

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BIOCIDAL CONTAMINANTS

     A few studies have been conducted on the removal  of bio-
cidals by osmotic membranes (  46,  126, 191).   Excellent
removals were reported for a wide  variety of  pesticides,
insecticides, and herbicides including chlorinated hydrocarbons,
organophosphorus compounds, and halogenous cyclodienes.
However, a considerable amount of  this removal  can be  attributed
to adsorption or absorption on the membrane itself.   Since
these tests were for short time periods relative to  commercial
application, the long-term rejection may be more complex and
may depend upon whether the contaminant is adsorped  or absorbed
and upon the diffusion rates through the membrane.

     With such a large percentage  of the removal being related
to adsorption/absorption, it is clear that different types of
membrane materials will show significantly different results.
For example, cellulose acetate (CA) membranes show rather
poor performance on the more polar randox and atrazine, whereas
the less polar polythyl enimine-based membranes showed satis-
factory performance.  Since the active surface on some types
of membranes is on the order of a  few tenths  of a micron, any
significant amount of absorption can change the membrane compo-
sition and possible rejection of other contaminants.

     Edward and Schubert (191) summarized some results of various
studies using cellulose acetate (CA) membranes for the removal  of
the common pesticide 2, 4-D.  Results varied  widely from 57 to  99+
percent removal depending on influent concentrations, esterifi-
cation, and feed rate.  Performance for removal of the  insec-
ticide lindane was also sporadic, ranging  from  rather poor
removals up to 84 percent.  DDT and ODD have a  very low solu-
bility and tend toward micelle formation  thus enhancing RO
performance.  Reported DDT  and ODD removals were  97 to  99
percent (157, 191 ).

     Chian et al. (126) performed a detailed analysis of  the
performance of RO units in  removing biocidals.  Two types of
membranes were evaluated, cellulose acetate  (CA)  and cross-
linked polyethylenimine:  (NS-100).  With each membrane,  rejection
of all types of pesticides  (chlorinated hydrocarbons, organo-
phosphorus, and miscellaneous) was  greater than 99 percent.
Specifically, the following chlorinated pesticides were retained
at greater  than 99  percent:   aldrin,  lindane, heptachlor, hepta-
chlor  epoxide, DDE,  DDT,  and  dieldrin';

      Of the organophosphorus  pesticides,  diazinon was  removed
at greater  than 98  percent, and methylparathion.  malathion,
and  parathion at  greater  than  99  percent.  The  lowest  removals
were  reported with  the CA membrane  on  randox  (72  percent) and
atrazine  (84  percent).  A  significant  portion of  the  pesticide
removed was  adsorbed  on  the membrane  itself:  about 80  to 95

                               227

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 percent for hydrocarbons, 30 to 50 percent fororganophosphorus
 compounds, and 5 to 60 percent for the miscellaneous pesticides.

     Bennett et al . ( 46  ) reported on the removal of organic
 refractories including some biocidals.  They found that lindane
 removal was 84 percent;  DDT, 99+percent; and  casein, 99 percent.

     The literature data indicate that removal of biocidals is
 highly variable, depending not only on contaminant concentra-
 tions and membrane characteristics, but on synergistic effects
 of other components in the water.  In any case, RO provides a
 high level of treatment  for many of the common pesticides and
 insecticides.

 SYNTHETIC/ORGANIC CONTAMINANTS

     The performance of  RO membranes with respect to removal of
 synthetic/organic contaminants is similar to that of many of
 the biocides.  In general, these contaminants can be adsorbed,
 absorbed, rejected or transmitted by the membrane, w.ith removals
 depending on chemical  species and membrane type.  In general,
 larger molecular weight  compounds are readily rejected or
 sorbed by the membrane, whereas low molecular weight compounds
 (<100) are more likely to pass through.

     Studies by Duvel  and Helfgott (189) on cellulose acetate
 (CA) type membranes have shown that rejection of low molecular
 wet organics depends upon the molecular weight and molecular
 size (as determined by steric geometry, with the size being more
 important);  it  also depends  on the ability of the molecule to
 form hydrogen bonds.  The hydrogen bonding behavior affects the
 solubility in the membrane surface and hence the permeability.

     Studies by    Hamoda et al.  (281) have shown that high
 flux membranes  can be  developed that have good rejections (>99
 percent)  of  tested organic compounds such as sucrose, glutamic
 acid,  starch,  sodium stearate, ABS, LAS, and beef extract.
 Cruver (148)  reviewed  similar contaminant removals and listed
 sucrose at 99.9 percent and  glucose at 99.5 percent.

     Bennett et al. (46) performed a comprehensive study of
 the removal  of  organic refractories by RO.  Results showed
 that the  RO  process is capable of producing a product water
 that is extremely low  in organic  matter in aqueous solution or
dispersion,  with  the exception of those organic compounds that,
when in solution  or dispersion, have a lower vapor pressure
 than water.

     The  classes  of compounds  that do not appear to be well
 rejected  and are  present in  wastewater effluents include com-
 pounds such  as  methanol ,  ethanol ,  and phenol.  No data were
                              228

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found on the low-molecular-weight,  halogenated hydrocarbons
such as chloroform,  bromoform,  halogenated ethane,  or ethylene
compounds; but,  based on the present theoretical  knowledge,  one
would expect the removals to be poor.

BIOLOGICAL CONTAMINANTS

     Due to the  large size of biological  contaminants, including
virus, relative  to the effective pore size of RO membranes,  high
reductions of these contaminants can be expected.

     Hindin and  Bennet (294) conducted microbiological studies
to determine the permeation through a porous cellulose acetate
membrane of microorganisms found in sewage effluent.  Their
results showed that Escherichia coli. Aerobacter aerogenes,
coliphage T-7 and X-175. and Streptococcus narcesence were all
removed 100 percent by the RO unit, with the exception of one
test in which a leak in  the membrane may have permitted per-
meation.

     Cruver (148) reports that  several studies have  shown that
99.9 percent removals of bacteria  and virus  can  be  attained.
However,  even with these excellent removals,  RO  processes
are  not used alone for  disinfection because  of the  presence
of  imperfections  in  the  membranes.  These  systems  are  primarily
designed  for TDS  removal in which  small  leaks through  the
membrane  and at seal joints are generally  inconsequential.
Nevertheless, these  leaks could be  significant when they  reduce
the  removal of  virus and bacteria  from 99.9999  to  98 percent.
To  depend  upon  these systems for 100  percent biological  con-
taminant  removal  would  require  continuous  monitoring for
biologicals and a degree of  quality  control  that would be
considered  beyond  the  state  of  the art for field systems.

      The  present  literature  indicates  that whereas removals
of  biological contaminants  with RO are very good,  they are  not
as  high or as fail  safe as  other disinfection practices'
 (chlorination,  ozonation).   It should  also be remembered  that
RO  is  only a  separation process,  not a destruction unit,  and
 that the  biological  contaminants,  once  removed,  will remain  in
 the waste solution.
                                229

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                           SECTION 11

           EPIDEMIOLOGICAL AND PATHOLOGICAL  EVALUATION
                   OF WASTEWATER CONTAMINANTS
 INTRODUCTION

     Many contaminants contained in municipal wastewater are
 known to produce adverse human health effects.  A number of
 elemental, biocidal, and synthetic/organic constituents have
 been clearly identified as potential carcinogens; some have
 even been identified as being mutagenic or teratogenic.
 Although the epidemiological effects of various viruses and
 bacteria are known and predictable, knowledge of the health
 risks of certain other contaminants is incomplete or lacking.
 Moreover, some chemical substances work not only in isolation
 within the human body, but may react synergistically (two or
 more chemicals combining to produce a net effect that is
 greater or lesser than that produced if the chemicals act
 independently).  A multiplicity of factors is involved in
 such reactions, and knowledge of potential health risks is
 scant.

     Literature detailing the epidemiological and pathological
 effects of wastewater constituents has been surveyed; the
 principal health problems posed by these contaminants are
 summarized below.  A sound understanding of human physio-
 logical reactions and consequent public health threats will
 better prepare responsible authorities to assess treatment
 performance and set acceptable standards.

     Present standards controlling wastewater discharges and
drinking water supplies have been assumed by many to guarantee
adequate protection of public health.   However, recent in-
vestigation has shown that some residual  organics,  carcinogenic
chlorinated hydrocarbons, synthetic compounds, trace elements,
and biocides are harmful  even in extremely small concentra-
 tions.   Existing standards are called into question by this
 increasing knowledge:  there may be no "safe" threshold for
 some of these chemicals.   Growing epidemiological and patho-
 logical evidence must be taken into account if discharge and
drinking water standards are to safely ensure public well-
 being.
                              230

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WATER QUALITY  PARAMETERS

     Suspended solids,  BOD,  TOC, and most other constituents
of general  water  quality  have  no direct effect on public
health.  However, certain constituents may become associated
with other, more  directly harmful, contaminants.   The sur-
vival and potential  health threat  of such contaminants may be
magnified as a result of this process.  Moreover, nitrogen
species present in wastewater can  directly affect human
health.

Nitrogen

     Nitrogen in  wastewater effluent is usually found in one
of the stable forms  (ammonia, nitrate, or organic nitrogen)
rather than the more hazardous nitrite form.  Nitrates and
nitrites occur in drugs, food, and water.  Man is continually
exposed to small  amounts of these  substances, which usually
cause no harm.  In high concentrations and under special cir-
cumstances, however, they may cause illness and even death.
Sapp (572) and the Hazardous Waste Advisory Committee of the
EPA  (484) consider nitrite, in particular,  a significant
health problem.

     Nitrite toxicity is the major health problem associated
with these nitrogen species since  nitrate easily reduces to
the  toxic nitrite form.  Such a conversion may occur outside
the  human body in food or water containing nitrates  •  Con-
version can also  take place inside the body through  the
action of intestinal bacteria on  ingested nitrates.

     Nitrate/nitrite conversion that occurs during  digestion
requires special  conditions likely to be present only in
infants.  The foremost prerequisite is the  presence  of
nitrate-reducing bacteria  in  the  upper gastrointestinal
tract.  Such  bacteria are  not normally present so high  up  in
the  intestinal tract.  This circumstance, however,  may
occasionally occur in infants, particularly those with  gastro-
intestinal infections and  a gastric pH insufficiently acidic
to kill the bacteria.

     Acute nitrite toxicity  (methoglobinemia) occurs when
hemoglobin (the oxygen-carrying red pigment of blood) is
oxidized into methemoglobin  (a brown  pigment  incapable  of
carrying oxygen).  Methemoglobin  constitutes  about  1  percent
of the total  hemoglobin of  a  healthy  adult  and up to
approximately 4 percent of  that of a  healthy  newborn  infant.
Cyanosis results when roughly 15  percent of the  hemoglobin
in blood is converted  into  methemoglobi n; when tnethemogl obi n
constitutes 70 percent or  more of the total  hemoglobin,
oxygen transport is severely  impeded, and death  may occur  (484)


                              231

-------
      Infants,  then,  are particularly  prone  to  nitrate-
 induced methemoglobinemia.   In  addition  to  the  presence of
 nitrite-reducing bacteria in the upper gastrointestinal
 tract as mentioned above, (1) the hemoglobin of very young
 infants is oxidized twice as rapidly as that of adults by
 nitrate to form methemoglobin; (2) the red blood cells of
 infants are not able to reduce methemoglobin into hemoglobin
 as well as adult cells; and (3) the total  fluid intake of
 infants per unit of body weight is much greater than that of
 adults.  Thus, for a given concentration in fluids,  infants
 consume proportionately more nitrate  than  adults.

      The consumption of water containing high levels of
 nitrates has accounted for many more  cases of methemoglobin-
 emia than  all  other causes combined.   Methemoglobinemia of
 such etiology  has been reported only  in infants, although one
 study documents one occurrence resulting from the use of
 nitrate-contaminated well  water for  peritoneal  dialysis in
 an adult.   In  the United States only  one case has been
 associated with water from a public water  supply;  all  the
 rest (about 300)  have been due to  well  water (484).

      Standards for  nitrates  in  drinking  water limiting nitrate
 to 10 mg/i expressed as nitrate-nitrogen  (45 mg/£  expressed
 as nitrate) were  set by the  U.S.  Public  Health  Service in
 1962.   The 10-mg/£  nitrate-nitrogen level  was  set  because
 there  had  been no  reports  in this  country  of infantile
 methemoglobinemia associated with  the  ingestion of water
 containing nitrate  at  levels below 10  mg/l.   In addition,
 this  level  was set  because  it  was  a standard  that  could  be
 met  easily by  most  municipal  water supplies.   After  publica-
 tion  of  these  standards, however,  data  reported from  other
 countries  revealed  that a  small percentage  of  cases  had
 occurred where the  water nitrate-nitrogen  content  had  been
 below  10 mg/£.

     As a  consequence,  the 1962 standards are currently under
 revaluation.   Several  studies  have been designed to determine
 more specifically the exact  nitrate levels  in water required
 to cause elevated levels of  methemoglobin and clinical
 evidence of methemoglobinemia in infants.   Preliminary re-
 sults suggest  that the  1962  standards provide adequate pro-
 tection against clinical methemoglobinemia.  However,  sub-
 clinical elevations of methemoglobin have been  found in
 infants with diarrhea or respiratory disease, consuming water
with a nitrate  content below the 10 mg/t level  (484).

     In contrast to the relative wealth of data on acute
toxicity in humans,  reliable data are  lacking on the physio-
logic effects,  if any, of chronic nitrate/nitrite toxicity
or of mild, noncyanotic methemoglobinemia.   Studies in
animals indicate that nitrates and nitrites may, on occasion,

                               232

-------
cause vitamin  A deficiency,  and  that nitrates may have an
antithyroid effect by increasing the need for iodine.   No
data are available to indicate whether such effects can
occur in man.

     Chronically elevated levels of methemoglobinemia  may
have some effect on the human brain:  abnormal  changes on
electroencephalograms have been observed in rats given 100 to
2,000 mg/£ of sodium nitrite each day for two weeks.  A
Russian study purports to show decreased response to visual
and auditory stimuli in school children with a  mean methemo-
globin level of 5.3 percent of total hemoglobin.  However, the
study was poorly controlled, and the results are inconclusive.
There have been patients with hereditary methemoglobinemia
and mental retardation, but the association may be coincidental
Most patients with hereditary methemoglobinemia show no
mental or neurologic abnormalities (484)

     Nitrosamines  formed  by  the  reaction  between  nitrites  and
amines have been proven hazardous  to  human  health.   Nitrites
and/or precursor nitrates  are  found  in  foods, water, and  drugs;
amines are found in tobacco  smoke,  beer,  tea, wine,  and  tooth-
paste as wel1.

     Nitrosamines  have potent biological effects, including
acute cellular injury (primarily involving the  liver), car-
cinogenesis, mutagenesis, and teratogenesis.  To date,
approximately one  hundred nitrosamines have been tested in
animals.  The vast majority has proved to be carcinogenic.
Many organs (liver, esophagus, and kidneys) that are common to
diverse species of animals are susceptible to the cancer-
producing effects  of these compounds.   These effects can be
elicited experimentally by various routes of nitrosamine
administration (oral, intravenous, inhalation)  at extremely
low doses.  In some instances, cancer can develop after a
single exposure(484).

     Concerns about potential nitrosamine hazards to human
health arise  from the possibility for (1) contact with pre-
formed carcinogenic nitrosamines and (2) the formation of
carcinogenic nitrosamines within the human body after exposure
to precursor nitrites and amines.  The possible formation of
carcinogenic nitrosamines in the human gut through the
combination of ingested nitrites and amines is  of critical
concern.  Such reactions have been demonstrated to occur
both in vitro and in vivo (in animals).

     Studies in humans that were fed nitrate and a noncarcino-
genic nitrosamine precursor amine (diphenylamine) have  shown
that diphenylnitrosamine can be formed in the human stomach.
Nitrosamine determinations in these studies were made  by


                               233

-------
 thin-layer  chromatography, a method now known to give false
 positive  results.  Unfortunately, these data have not yet
 been confirmed using the newer and more reliable techniques
 of gas-liquid chromatography and mass spectrophotometry (484).

 ELEMENTAL CONTAMINANTS

     It is  often difficult to assess the health effects of
 metals and  their compounds:  many metals are essential to
 life at low concentrations but toxic when concentrations ex-
 ceed tolerance in man.  The situation is further complicated
 because the various chemical states of metals (pure metal,
 inorganic or organic-metallic compounds) react differently
 within the  body.  Individual differences between subjects,
 incubation  periods, and sites of accumulation of the sub-
 stances in  the body are also significant factors in toxicity.

     In addition, results from experiments with animals may not
 be readily  applicable to humans.  Experimental animals such
 as rats and mice have a much shorter life-span than man and
 react and respond differently to chemicals because of their
 own distinctive physiological processes.

     Table  97  gives a comprehensive summary of the presence
 of metals in the environment, their toxicity to humans, and
 their half-life in the body (the time it takes for one-half
 the chemical to be excreted).  Five heavy metals --cadmium,
 lead, mercury,nickel as nickel carbonyl, and beryllium --
 represent known hazards to human health.  Lead, mercury, and
 cadmium are particularly insidious,because they can be re-
 tained in the body for a relatively long time and can
 accumulate as poisons.  Antimony, arsenic, cadmium, lead, and
mercuric salts are the most toxic.   Discussions of fatal
 doses and other considerations can be found in each individual
metal section.

 Lead

     Lead  is a cumulative  poison.  However, except  in cases of
 prolonged  exposure  at  high  concentrations,  most of  it is absorbed
 into the blood and  is  later  excreted  in  the urine.  The blood  lead
does not rise to acute levels; however,  a small portion of the
daily lead intake gradually accumulates  in bones, where it
 is normally insoluble and harmless.   Under certain conditions,
 such as periods of high calcium metabolism in feverish
 illness, cortisone therapy, or old  age,  this accumulated lead
can be released suddenly into the blood  at toxic levels.  A
 fatal dose of absorbed lead has been estimated to be 0.5 g;
 ingestion of more than 0.5 mg/£/day may, because of the above-
mentioriPd accumulation, cause toxicity and death.
                              234

-------
                                         METALS  IN THE  ENVIRONMENT AND THEIR TOXICITY1
ro
CO
en
Metal Food
Antimony
Arsenic
Barium
Beryl 1 i urn
Cadmi urn
Chromium
Copper
Iron
Lead
Manganese
Mercury
Nickel
Selenium
Silver
Tin
Zinc
a Data primarily
(ppb) (ppb)
and Water Air
100
400-900
735
12
1.7
—
30
0.04
20 to 100 7.4
245
1,325
15,000
300
4,400
25
600
62
60-80
7,300
14,500
from Drei
Oregon State University
b Copper sulfate

1.1
11.4
84
46
28.8
—
2.36
--
—
0.6
16.8
i
sbach (181 )
(288)

Oral dose
producing
toxicity (mg)
100
5-50
200
--
3
200
50-250
—
—
--
—
--
5
60
2,000
—
and


c A two-yr old child
Fatal
dose
(ingestion)
100-200 mg
120 mg
1 9
—
—
5 g
10 gb
5-10 gc
0.5 g
ft
20 mg - 1 g
—
^
29f
	
10gg
d Mercuric salts
e Methyl mercury
f Silver nitrate
g Zinc sulfate
Total
Body content
(mg)
7.9
15-20
22
0.3
50
1.8
72
4,200
120
12
--
10
14.6
1
17
2,300




Whole body
half-life
(days)
38
280
65
180
25 years
616
80
800
1,460
17
-,«e
70
667
n
5
35
933





-------
      Lead prevents the formation of hemoglobin in the blood
 by interfering with the synthesis of certain precursors
 (prophyrins), which leads to the anemia present in chronic
 lead poisoning.   Lead also inhibits the sulfhydryl enzymes
 that catalyze many of the metabolic pathways,  including the
 biosynthesis of  heme.  The effects of lead on  the brain and
 peripheral  nervous system are most serious,  manifested as gas-
 trointestinal or central  nervous system disturbances and
 anemia.   Symptoms of acute poisoning include metallic taste,
 abdominal  pain,  vomiting, diarrhea, black stools, oliguria.
 collapse,  and coma.   Symptoms of chronic poisoning in early
 stages  include loss  of appetite and weight,  fatigue, head-
 ache,  lead  line  on gums,  loss of recently developed skills,
 and anemia.   In  advanced  stages, there  is intermittent vomit-
 ing,  irritability; nervousness; lack of coordination; vague
 pains  in  arms, legs,  joints,  and abdomen; paralysis; disturb-
 ances  of  menstrual cycle; and abortion.   Exposure to tetra-
 ethyl  lead  or tetramethyl lead  causes  insomnia,  disturbing
 dreams, emotional  instability,  hyperactivity,  and even toxic
 psychosis.   Severe symptoms  include persistent  vomiting,
 papilledema,  ataxia,  encephalopathy  (any disease of the brain)
 elevated blood pressure,  cranial nerve paralysis, delirium, con-
 vulsions, and  coma (131).

     There are up  to  100 cases of lead poisoning reported in the
 U.S. annually; an  average of 10 are fatal.  Most of the fatalities
 are related to children who ingested lead-based paint from homes
 built before  1940; however, 7 cases of lead poisoning were
 reported from drinking well water in Australia  in 1973 (57, 144).
 The well water contained a soluble lead content of about 14 mg/l\

 Mercury

     Neither methyl nor elemental mercury  is normally  found
 in dangerous concentrations in  air,  water, or most  common
 foodstuffs.  There are three  principal ways  in which  man  can
 be poisoned by methyl mercury:   (1)  when  food is  consumed  that
 has been contaminated with methyl mercury, e.g.,  seed  con-
 taining mercury fungicides (HgCl2);  (2) when methyl  mercury
 used or formed in  industrial processes is  intentionally or
 unintentionally dumped into natural waters,  reaching man
 directly through  the water and  indirectly  through  the  food
 chain;  and (3) when nontoxic inorganic or  organic  phenyl
mercury is converted into toxic alkyl mercury compounds by
microorganisms in the environment and is passed on  to  man
 through the food  chain (329).

     The acute toxicity of methyl mercury  is the  result  of
 almost complete (98 percent) absorption of the compound
 from the gastrointestinal tract.  Ingested metallic  mercury
 is not toxic since it is  not absorbed.  Mercurous  chloride
 and organic mercurials such as  acetomeroctol, ammoniated

                              236

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mercury,  merbromin,  mercocresol,  and  mercury  protoiodide
are not likely to cause  acute  poisoning  because  they  also
are poorly absorbed.   The  single  fatal  dose of these  compounds
is 3 to 5 times the  fatal  dose of soluble  mercury  salts.  The
mercurial diuretics  (mersalyl, meralluvide, mercurophyl1ine,
mercumati1 in, mercaptomerin,  chlormerodrin, and  merethoxyl1ine)
are almost as toxic  as mercury salts.   Volatile  diethyl  and
dimethyl  mercury are 10  times  as  toxic  as  mercuric  chloride
(695).   The fatal dose of  mercuric salts is 20 mg  to  1  g.   The
biological half-life of  methyl mercury  is  estimated  to  be about
70 (30 to 100) days  as shown  in Table 97 (615,672).

     Acute poisoning by ingestion of mercuric salts causes
metallic  taste, thirst, severe abdominal pain, vomiting, and
bloody diarrhea.  Death is from uremia  (an excess of urea
and other nitrogenous waste in blood).  Ingestion of insol-
uble or poorly dissociated mercuric salts (including mercurous
chloride  and organic mercurial compounds) over a prolonged
period causes urticaria progressing to  weeping dermatitis,
stomatitis, salivation, diarrhea, anemia, liver damage, and
renal damage progressing to acute renal failure with anuria
(total  suppression of urine).  In children, repeated ad-
ministration of calomel  (Hg2Cl2)  appears to  be  the cause of a
syndrome   known as erythredema polyneuropathy.   In  fatalities from
mercury  poisoning, the pathologic findings are  acute tubular
and glomerular  degeneration or hemorrhagic glomerular
nephritis.   The  mucosa of  the  gastrointestinal  tract shows
inflamation,  congestion, coagulation, and corrosion  (181).

     Mercurialism is  manifested  primarily in kidney, liver,
or brain  damage  in  animals.   Exposure to  inorganic  mercury
compounds  usually results  in  kidney  damage,  while  alkyl
mercurialism  is  characterized by  brain  damage.   However,  some
degree of both  kidney and  neurological  injury results  from
exposure  to  either  category  of mercurials.   Mercury poisoning
apparently  damages  Kreb's  cycle  enzymes (which  catalyze the
oxidation of  tricarboxylic acids) and  protein synthesis,
leading  to  kidney and  brain  damage  (216).

     Methyl mercury has an affinity for the fetus and is terato-
genic  in  its  effect, as it readily penetrates to the fetus through
the  placenta.   In addition, the cytogenic toxicity of methyl
mercury  is  potentially greater than that of any other known sub-
stance.   The  urine and especially the feces are the most important
means  of mercury elimination.

     The tragedy of Minamata  Bay,  Japan,  which  occurred from
1953 to  1961,  is one  of the  best  documented  cases  of mercury
poisoning.   In  essence, it was concluded  that the  disease  --
which  had felled many  inhabitants of the  fishing  villages
on  the shores  of Minamata  Bay --  had  resulted from mercury
poisoning.   A chemical  plant  in  the  area  used mercurv  chloride

                               237

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as a catalyst  in the production of vinyl chloride.  The waste
containing the mercury washed off the product was discharged
into the bay,  and was ingested by the shellfish therein.  Some
114 cases of "Minamata disease" were reported, as well as
44 deaths and  22 cases of brain damage  in 400 live births (423)

     A similar disaster struck at Niigata, Japan, where 120
persons were poisoned (423).

Nickel
     The fatal dose of nickel is not know, but its whole body
half-life is about 667 days.  Inhaled nickel carbonyl decomposes
to metallic nickel, which deposits on the epithelium of the lung.
This finely divided nickel is rapidly adsorbed and damages the
lung and brain.  The principal manifestation of nickel carbonyl
poisoning is dyspnea (difficult respiration).  Workers exposed
to nickel carbonyl show a high incidence of lung cancer, and
some workers develop dermatitis (181).  Very little is under-
stood about the adverse health effects of nickel in waste or
water supplies.

Cadmium

     Cadmium has become the most recent and perhaps the most
acute menace among the widely used heavy metals.  A great amount
of current research is being conducted regarding the fate and
distribution of cadmium to the environment.

     Nearly all this literature concerns the quantification of
cadmium in wastewater and sludges, and the effects of disposal
to land and water systems.  However, there is little information
available concerning the direct health hazards of cadmium present
in wastewater and water supplies.   The average  American  citizen's
daily intake of cadmium from foods  and  water supplies  is
estimated to be between 0.02 and 0.1 mg/d.  The oral dose of
cadmium producing toxicity is about 3 mg, but its fatal dose is
not known.   The whole body half-life of cadmium is 25 years
(Table 97).

     Circumstantial evidence appeared to point to some link
between trace metals of cadmium and hypertension.  Recent studies,
however (615), have disagreed with this finding, and the general
consensus now is that there is no  link between cadmium ingestion
and hypertension.   Inhalation of tobacco smoke is a major source
of cadmium accumulation in man.   Only about 5 percent of the
cadmium ingested through food or drink is absorbed by the body,
while 10 percent to perhaps as much as 50 percent of inhaled
cadmium is retained (615).

     Cadmium tends to accumulate in liver and kidney tissues
because of its very long biological half-life in man (estimates

                               238

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range from 10 to 25 yr,  compared with about 70  days  for  methyl
mercury).  Excessive levels in the kidney cortex (over 200  mg/g
wet weight) results in proteinuria.   Therefore, the  cadmium con-
centration in water must be kept low (615).  The Environmental
Protection Agency (EPA)  in its 1975  Interim Primary  Drinking
Water Standards set a mandatory limit of 0.010  mg/£  for  cadmium
concentrations in drinking water; the World Health Organization
set a limit of 0.05 mg/8, .  The results of a U.S. Geological
Survey investigation of 720 waterways showed that 4  percent had
concentrations above EPA standards (423).

     Cadmium has reportedly caused a number of  deaths from oral
ingestion of the metal in food or water.  For example,  Japanese
people living along the Jintsu River suffered for years  from an
unknown malady characterized by kidney malfunction,  a drop in
the phosphate level of the blood serum, loss of minerals from
the bones, and osteomalcia resulting in bone fractures  causing
intense pain.  One of several causes of the malady implicated
was a cadmium, zinc, and lead mine that was discharging wastewater
into the river.  The disease, known as i tai i tai, was contracted
either by  drinking water from the river or by eating rice that
had accumulated the metal from irrigation water  (123).   In
another situation, there was an outbreak of acute gastroenteritis
in 13 children who drank orange soda contaminated with  cadmium
at a concentration of 16 mg/S,  .  The contamination was  caused
by the orange soda coming in contact with  the  soldered joints
in the tank of  the soft drink machine  (57, 60).

Chromium

     Chromium,  which  exists  in various oxidation  states (+2+3
and +6),  appears  to  be most  toxic to man as the  hexavalent
chromium  ion.   The fatal  dose  of  a  soluble chromate  such as
potassium  chromate,  potassium  bichromate,  or chromic acid  is
approximately 5 g.   Acute  poisoning  from ingestion is manifested
by dizziness,  intense thirst,  abdominal  pain,  vomiting, shock,
oliguria  (scanty  urination),  or  anuria.  Hemorraghic nephritis
occurs,  and  death  is  from  uremia.

      Repeated  skin  contact with  chromium leads  to incapacitating
eczematous dermatitis with edema  and  slowly  healing  ulceration.
Breathing  chromium  fumes  over  long  periods  of  time causes  pain-
less  ulceration,  bleeding, and  perforation  of  the nasal septum
accompanied  by  a  foul  nasal  discharge  (181).

      Whether  chromium is  carcinogenic  is questionable at  this
time.  However, the  incidence  of lung  r"ncer in ^ork^r? exposed
to  dusty chromite,  chromic oxide,  and  chromium ores  is  reported
to  be  up to  15  times the  normal  rate (181).
                               239

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     Experiments on rats  showed  no  toxic  response from
drinking water  containing 0.45 to 25 mg/£ in chromate and
chromium ion form  (408)-

     Although a potential health hazard exists, evidence of
health problems resulting from chromium present in waste-
waters is lacking  in the literature.

Arsenic

     Arsenic is widely distributed in nature.  It is present
in toxic concentrations in many water supplies:  cattle in
New Zealand have died from drinking water containing natural
arsenic, and there are several areas of the world where there
is a high incidence of skin cancer among people drinking well
water that contains natural arsenic (423).  In 1971  the U.S.
Geological Survey  found that 2 percent of the samples drawn
from 720 waterways were above their standard of 0.05 ppm for
arsenic.

     Before the advent of modern insecticides, arsenic com-
pounds were widely used to treat food crops.  Although arsenic
can stimulate plant growth in very low concentrations, in
excessive quantities, as little as 1 ppm of arsenic  trio-
xide arsenic  can be injurious.  Organic arsenicals,  such as
arsphenamine and dimethylarsinic acid, release arsenic
slowly and are less likely to cause acute poisoning.  But
arsenic accumulates in the body, so decreasingly small doses
can ba lethal.   Repeated or prolonged intake has a  cumulative
to.xic effect,  presumably caused by the arsenic combining with
sulfhydryl  (-SH) enzymes and interfering with cellular
metabolism.

     Chronic poisoning from ingestion or inhalation  of
arsenic can cause anemia,  weight loss, polyneuritis, optic
neuritis, dermatitis, cirrhosis of the liver, abdominal cramps,
chronic nephritis, and cardiac failure (181).

     Arsenic is suspected to be carcinogenic but not tumori-
genic (29,  340, 363.)-  Chronic exposure to arsenic-contaminated
water of 0.3 mg/£  is also suspected to be related to the
increased incidence of hyperkeratosis (hypertrophy of the
horny layer of the epidermis) and skin cancer ;  chronic
exposure at levels of 0.8 mg/l may be related to gangrene of
the lower 1 imbs (265 ).

     Arsenic is one of the impurities in mineral phosphate
deposits, a source of commercial water softeners.  Concen-
trations of 10 to 70 ppm of arsenic have been detected 1n
several  common household detergents.  Baby rash, hand rash,
skin eruptions, and other types of dermatitis allergies are


                              240

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associated with arsenic in  detergents.   Much  of the  sewage
containing such detergents  is  dumped  into  waterways  (423).
There is a danger that arsenic in laundry  water may  be
absorbed through unbroken skin.

     The principal  oxidation states  of  arsenic  are +3 and  +5.
In the +3 state, arsenic forms arsenious oxide; in the  +5
state, arsenious acid; and  in  the -3  state,  arsine gas.
The fatal dose  of arsenic trioxide is  about  20  mg.   Arsenic
poisoning is manifested by  gastrointestinal  disturbances;
death is due to circulatory failure  as  a result of hemolysis
(destruction of the red blood  cells).

Copper

     The biological properties of copper are  such  that  it  is
a useful biocide, especially as  an algicide.   Various  salts
of copper (one  of the most  common  being copper sulfate -
CuS04) are used as  astringents,  deodorants,   and antiseptics.
These salts are all water soluble, and  their  protein-
precipitating characteristics  form the  basis  of their  astrin-
gent and antiseptic effects.  The copper mined  in  the  United
States for these effects alone amounts  to  some  15  million
Ib/yr and accounts  for about 40  percent of all  chemical uses
of the metal.

     Trace amounts  of copper are essential for  normal
metabolism, and relatively  large concentrations can  be
tolerated by most animals including  vertebrates.  The  effect
of copper on aquatic organisms varies greatly;  microorganisms
including algae, are highly susceptible.

     Small quantities of copper  are  not considered  toxic,
but higher concentrations are  known  to  cause vomiting  and
liver damage (672).   Fatalities have been reported  following
the ingestion of 10 g of zinc  or copper sulfate 0.81 ).   An
outbreak of acute copper poisoning occurred  in  a school in
Mesa, Arizona.   The outbreak began 10 min  after the  students
drank an orange-flavored drink that  had been  kept  in a  brass
container for 17 hr (57).   An 8-oz  glass  of  the drink
contained 8.5 mg of copper.

Selenium

     Selenium is an excellent  example  of the  fine  balance
that can occur  in nature between the  beneficial and  injurious
effects of a natural substance.   An  essential micronutrient
for some plants, selenium is one of  the most  toxic substances
to occur naturally  in the environment;  concentrations  only
slightly above  those needed for  growth  of  plants may be
poisonous to animals.   A selenium compound that was  used to


                              241

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 kill  insect pests  in fruit orchards  left  a  residue  in  the
 fruit.   Cattle that were feeding  on  this  fruit  contracted
 a  chronic form of  livestock poisoning called  alkali  disease.
 Ingestion of forage containing  about 25  ppm can cause  this
 disease  when the  forage  is eaten  for several  weeks  or  months
 (423).

      As  long ago  as 1936,  inhabitants of  seleniferous  areas
 of  South Dakota and Nebraska  complained  of  gastrointestinal
 symptoms and were  found  to excrete  large  quantities of selenium
 in  their urine (423).  There  is also a report of selenium
 toxicity from a three-month exposure to  well  water  containing
 9 mg/£ of selenium.

      The American  Conference  of Governmental  Industrial
 Hygienists  recommends  a  selenium  limit of 0.2 mg/cu  m  in
 air and  0.01  ppm in water.

 Beryl 1ium

      Although  the  fatal  dosage of beryllium  is  not  known,
 in  1971  the  EPA placed beryllium  on  the  list  of hazardous
 pollutants.   From  1941 to  1967, 760  cases of  berylliosis
 were  recorded  (181).

      Soluble  beryllium salts  are  irritating  to  the  skin and
 mucous membranes,   and  induce acutepneumonitis with  pulmonary
 edema.   At  least part  of the  changes  present  in  acute
 pneumonitis  and berylliosis (chronic  pulmonary  granulomatosis)
 develop  from  hypersensitivity to  beryllium  in the tissues.
 Weight loss  and marked dyspnea,  which are  symptoms of
 berylliosis,  begin  3 months to 11  years after the first ex-
 posure (inhalation).   Eczematous dermatitis with a maculopop-
 ular,  erythematous  visicular  rash appears in  a  large percentage
 of workers exposed  to  beryllium dusts.
Barium

     Absorbable salts of barium, such as  the  carbonate,
hydroxide, or chloride, are used in  pesticides;   the sulfide
 is sometimes used   in depilatories  for external  application.
A soluble barium salt such  as the  carbonate or  hydroxide may
be present as a contaminant in the insoluble  barium sulfate
used as  a radiopaque contrast medium.

     The   fatal dose of absorbed barium is approximately 1  g.
The principal manifestations of barium poisoning are tremors
and convulsions.   Barium presumably  induces a change in
 permeability or polarization of the  cellular membrane that
 results   in stimulation of all cells  indiscriminantly (423).
                               242

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Other Elements

     Antimony will be considered a potential hazard if levels
of the element increase.  It is present chiefly in industrial
wastes, typesetting metal, pewter, and enamel ware.  Antimony
is suspected to cause a shortened life-span and heart
disease in rats (423) .

     Metal alloys and smoke suppresant in power plants are
the major sources of manganese as a pollutant.  Although
manganese in trace amounts is an essential element to man,
increased levels may imperil health.  The findings in one
death -  suspected to be caused by the ingestion of manganese-
contaminated drinking water -  were atrophy  (a wasting of the
tissues) and disappearances of cells of the globus pallidus
(in the brain).  Experimental animals show inflammatory
changes in both gray and white matter  (423).

BIOCIDAL CONTAMINANTS

     There is significant information in the literature^
concerning biocidal contaminants, their chemical and physical
characteristics, toxicology, analytical chemistry, and
impacts on health and the environment.  In both chemical  and
medical literature, hundreds of cases of acute poisoning
resulting directly or indirectly from such pesticides have
been reported.  Table 98 summarizes  the  various  levels at  which
      fatal  dose, chronic poisoning,  and  acute  poisoning  occur.
Chlorinated Hydrocarbons

     Because of their persistence and nondegradational
characteristics, many of the relatively less  toxic  chlorinated
hydrocarbons, such as DDT, aldrin, and dieldrin,  have  been
banned and are being replaced by highly toxic  but less  per-
sistent organophosphorus pesticides.  The U.S.  EPA  is  pre-
sently conducting a program to  identify new,  less harmful
pesticides that can act as substitutes for those causing
the  problems.

     This decision to remove aldrin and dieldrin from the
market has been highly criticized.  The idea  that these com-
pounds pose  "an unreasonable risk of cancer"  is based on the
presence of  tumors in the  livers of mice that  were  given food
containing aldrin and dieldrin; some of these  tumors metasta-
sized  to the lungs.  However, it has been noted that similar
tumors can be produced by  other compounds, such as  DDT  and
phenobarbi tal ,  and can occur in mice on normal diets.
There  is, then, some question as to whether  the production
of  tumors in the  livers of mice given aldrin  or dieldrin is
a  reliable indicator of a  hazard to man.  The  general  dietary
intake of all major pesticides  except aldrin  and  dieldrin

                               243

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      Dieldrin
ro
      Lindane
      (Benzene
      hexachloride)

      Malathion
      Parthione
                           TABLE 98 .   BIOCIDES IN THE ENVIRONMENT AND THEIR TOXICITY*
Biocide LD5Q (oral)
mg/kg
DDT Rat 285
Rabbit 325
Fatal Doses
(g/kg)
0.4
Chronic
Poisoning
Not substantiated.
Having 648 ppra in
their body re-
mained well .
Acute
Poisoning
Severe vomiting within
30 min to 1 hr of 5 g.
Weakness and numbness of
the extremities. Appre-
hension and excitement
are marked.
Rat 60
Dog 68
Rabbit 45
Rat 135
Dog 120
Rabbit 130

Rat 2500
Rat 4
0.07
0.6
0.86
0.0014
Not been estab-
lished in man.
Impair liver func-
tion in animals,
occasional epilep-
tiform convulsions,

In animals, liver
necrosis.
In animals, colin-
esterase levels of
red blood cells
and plasma are re-
duced markedly.

Not established
in man.
Hype r ex c i ta b i 1 i ty,
tremors, ataxia, con-
vulsions.
Vomiting and diarrhea,
convulsions, circulatory
failure.

Headache, tremors,
nausea, abdominal cramps,
diarrhea, coma, heat
block.
Similar to those of
malathione, but more
severe and fatal.

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ro
     TABLE 98 .  (.continued)
Biocide ID™ (oral )
mg/kg
2, 4-D Mouse 375
2, 4, 5-T Rat 300
Dog 100
Fatal Doses
(g/kg)
0.7
0.6
Chronic
Poisoning
Weakness, fall of
blood pressure,
muscle damage.
Similar to 2, 4-D
Acute
Poisoning
Burning pain, painful
and tender muscle, fever,
paralysis, irreversible
fall of blood pressure.
Similar to 2, 4-D.
        Data primarily from Sunshine (626),  Dreisbach (181),  and McKee and Wolfe  (436).

-------
is well below the allowable standards that were established
in 1972 by the World Health Organization Council on Environ-
mental Quality.  Much of the DDT uptake (about 85 to 90
percent) comes from food; the remainder comes from air,
water, aerosols, cosmetics, and clothing.

      Because of  DDT's extremely low solubility  in water
(about 2 ppb), the body, which is essentially a water system,
cannot handle the liquid soluble substance and deposits it
in fat.  Quantities of DDT and other related pesticides do
not appear to build up continuously; instead, the pesticides
reach a plateau  or steady state (storage equilibrium) at
which they are being excreted and degraded at levels equal
to their intake.  Children may take 5 to 10 yr  to reach
storage equilibrium.  Little is really known about these
levels, which undoubtedly vary with different pesticides,
exposure, intake conditions, and individuals.

      Of real concern are the possible effects of long-term
exposure to low  levels of DDT and other pesticides.  Some
sublethal effects have been observed in animals (cellular
changes in liver tissue and other physiological and histologi-
cal effects); however, these effects cannot be extrapolated
to man.  Of course, there is still the suspicion that DDT
might eventually cause damage to human physiology.  It has
been  suggested,  for instance, that long-term exposure to
low levels of pesticides may cause cancer.  Research
neither supports nor contradicts this possibility, because
it is difficult  to control  or document experiments on humans
over  a longer period of time.

      Based on animal experiments,  the average lethal amount
of DDT is a single dose of about 8,000 to 14,000 mg/150-lb
person, although quantities as high as 109 ppm have been
found in sampling a general population.  A study was conducted
of persons accidentally or violently killed in Dade County,
Florida,  from 1965 to 1967.  The average concentration of
DDT in the fat of the bodies ranged from 5 to 22 ppm; there
was more in adults than in children, more in nonwhites than
in whi tes.

     Because the use of chlorinated hydrocarbon pesticides
has been  sharply curtailed, it is  therefore expected that
smaller quantities of DDT are being ingested and that
residues  in human fat will  decline.  However, the average
value of DDT, DDE, and isomers in  human fat samples in India
was 21.8  +_ 2.9 mg/kg in 1973 and 24.3 mg/kg in 1965.  This
would seem to indicate that the DDT storage status had not
undergone any significant change in those years.
                              246

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     A comparative study was performed of DDT and its
derivatives in human blood samples.   The study was conducted
in two areas of Ontario where DDT has been used in large
amounts.   The mean values of total  DDT in the adipose tissue
and blood samples were found to be  5.83 and 0.032 ppm,
respectively.  There was a significant correlation between
total DDT in the fat and blood, but there was no evidence
of any adverse effects of DDT on either of the populations
(78).

     In another study, tap water samples collected in the
Washington, D.C., area before treatment showed the presence
of DDT (0.17 mg/£), TDE (0.27 mg/£), and DDT-derived compounds
(.15 mg/£); no evidence of these compounds was found after
treatment.

     The EPA's ban on DDT has been  modified since the incep-
tion of the pesticide in 1972.  In  1974, DDT was used against
the tussock moth in northwestern forests and against the pea
leaf weevil in Washington and Idaho.  The EPA, however, states
that DDT will be used only against pests that cannot be
controlled  by other means and that will do economic damage
or threaten human health or safety.  Also, despite the
suspension  of aldrin and dieldrin,  the  EPA will  permit  their
use against termites and clothes moths, under certain circum-
stances.

     The toxic effects of carbaryl  , which is used against
DDT-resistant lice, were found  to be minimal at  the  levels
of 75 mg/l  (135).

     The residues of mirex  -  a chemical which  is used  to
control  the imported fire ant -  were discovered  in  the
fatty tissue  of  six persons from 1971 to  1972.   It was  con-
cluded that the  residues came from routes other  than direct
pest icide  usage  (478).
     The maximum allowable  concentration of most  of  the
pesticides  (as determined by  biological tests)  lies  below
l'mg/i,  but is as low as about  0.01 mg/l for such preparations
as atrazine,  malathion,  and thiometon(522).

     Workers  occupationally exposed  -   through  manufacturing
processes  -  to  aldrin,  dieldrin,  endrin, and  telodrin
(isobenzan) for  up  to  15 yr were studied  by  Versteeg and
Jugar  (622).   No  persistent  adverse  effects on  health  were
observed  in 52 workers  who  had  left  the company  and  were
traced.   The  average  pesticide  exposure in  this  group  of
workers  was 6.6  yr, and  an  average  of  7.4 yr  had elapsed
since  exposure.   No hepatic disease  or  convulsions  occurred,
and  no  new gases  of malignant disease  developed.  Most  of
the  workers experienced  no  unusual  illnesses.

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     Exogenous leukemogenic agents such as pesticides (DDT,
lindane, organophosphates) are being considered as potentially
contributory etiological factors that may activate a latent
leukemia virus in certain cells (617).

Organophosphorus Pesticides

     The organophosphates attack the neural  transmission
system of mammals and arthropods and thus interfere with
the function of the target organs.  Especially active are
those organophosphates that function by inhibiting carboxylic
ester hydroxylases (including acetylcholinesterase, which
is present in human erythrocytes, nerves, and skeletal
muscle; and cholinesterase, which is present in human
plasma and in the liver).  Miosis (contraction of the pupil),
is found in about 90 percent of the patients with moderately
severe or severe cases of organophosphate poisoning (704).

     Tamura et al. (634) conducted a statistical  and
epidemiologic investigation of the relationship
between the changes in the use of organophosphorus insecti-
cides and the recent increase in cases  of myopia  in 40,000
Japanese children from 1957 to 1973.  The study showed  that
in the year following any period when large  amounts of
organophosphorus insecticides were used, the morbidity  from
myopia in school children increased rapidly; conversely,
decreased use of the insecticides resulted in decreased
morbidity.  This it appears that the recent  increase in
myopia in school children was due, at least  in part, to
chronic intoxication of organophosphorus insecticides (634).

     Pediatric hazards associated with  organophosphates are
often reported (424).  Signs of toxicity are overaction of
the parasympathetic nervous system, nausea,  vomiting, diarrhea,
sweating, and abdominal  cramps.   Large  doses may  lead to
muscular paralysis and death from respiratory failure (424).

     Because organophosphorus pesticides are readily absorbed
through the skin, as well as by ingestion and  inhalation,
these pesticides present a particular hazard to agricultural.
workers who engage in mixing, loading,  and applying  the  con-
centrated materials (605).

     The incidence of organophosphorus  insecticide  poisoning
varies considerably throughout the world.  During  17 yr  in
Japan there were 19,000 cases of organophosphorus  poisoning
reported, resulting in more than 9,000  deaths.  By  contrast,
during 17 yr in Great Britain there were only  five  deaths
reported from this poisoning  (657).   Increased chromosome
aberrations were observed in patients suffering acute
organic phosphate insecticide intoxication.   The  frequency
of stable chromosome aberrations showed a significant  increase

                               248

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with malathion, trichlorfon,  mevinphos, and methyl parathion;
malathion induced an outstandingly high number of structural
chromosome aberrations.  Patients less seriously intoxi-
cated suffered milder chromosome alterations.   Even
in the absence of clinical signs of organophosphate poison-
ing by dichlorvos at low levels, the cholin  esterase
values were much lower than those of a nonworker control
population.  The decrease in enzyme levels was significantly
correlated with subjective health complaints:  sore throat
and loss of memory (43).

Herbicides

     Today over 40 weed killers are available, but the most
widely used are 2, 4-D (2, 4 - dichlorophenoxyacetic acid)
and 2, 4, 5-T (2, 4, 5 - trichlorophenoxyacetic acid).  In
general, these chemicals are rarely lethal to humans or
animals, do not persist for long periods of time in the
environment, and do not build up in the food chain.

     During the Vietnam war, South Vietnam suffered massive
military herbicide spraying.  It has been estimated that at
least one-third of the timber forests was destroyed, as
well  as 10 percent of all  cultivated land and at least 25
percent of the coastal Mangrove forests, which are the
breeding or nursery grounds for most offshore fish and
crustaceans (686).    However, there was no evidence in
Vietnamese hospital records that were examined by Thimann
(642)   that birth defects  could be attributed to the herbicide
spraying.

     Humans are exposed minimally to the phenoxy herbicides
through food; air and water are the primary sources of
exposure to these herbicides.  On the basis of air samples
collected from wheat-growing areas in the state of Washing-
ton,  it was estimated that an average person would be ex-
posed to 1.8 mg of phenoxy herbicide/day.   Rain and wind carry
the herbicides into water(114).   Workmen who were engaged
in the manufacture of herbicides were examined; the clinical
results were compared to those of a control population that
was not exposed to the 2,  4-D or 2, 4, 5-T.  No meaningful
differences were obtained; moreover, there were no chromosomal
effects  (114).

     In the fall of 1969,  the National Institute of Cancer
reported that 2, 4, 5-T was teratogenic and was responsible
for fetal toxicity at levels of 27 ^ 8 ppm.  The manufacturer
claimed that this herbicide was not teratogenic; that the
fetal  toxicity was caused  by 2, 3, 7, 8-tetrachlorodibenzo-p-
dioxin, known as dioxin (333).
                               249

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      At the dose level of 100 mg/kg/day of silvex, there
 were no effects on either the dams or fetuses of rats.
 Similar observations were also made with picloram.  Picloram,
 however, is much more persistent in soil than the other com-
 pounds.  Unlike DDT, it forms soluble salts and does not con-
 centrate in fat; in addition, the toxicity of picloram  is
 very low when compared to that of most other herbicides (333) .

      The widespread use of phenoxy herbicides has produced
 no demonstrable evidence of potential harm to man.  The
 herbicides used most widely (2,  4-D and 2, 4, 5-T) are
 degraded to nontoxic components  and do not bioconcentrate
 (653).

      An epidemiological  investigation was  made of tumor
 incidence  and mortality   in Swedish railway workers  exposed
 to various herbicides.   Among workers exposed to amitrole
 (3-amino-l, 2, 4-triazole), tumor incidence and mortality were
 significantly increased  and were slightly  dose related.   Nearly
 normal  conditions  were found in  those exposed to phenoxy
 acids.   Animal experiments suggest that amitrole may produce
 malignant  tumors in several  different organs, but tumors
 of the  thyroid and  liver have received the most attention
 (23).

      To receive a  letal  dose of  2,  4,  5-T, a  125-lb  woman
 would have to eat  the equivalent of her body  weight  of  material
 containing 380 ppm  of the  herbicide (based on the acute  oral
 toxicity expressed  in mg/kg).  Both 2, 4,  5-T and DDT in
 technical  form are  relatively nontoxic on  skin contact  (3,800
 mg/kg for  2,  4,  5-T and  2,500  mg/kg  for  DDT).   There  have been
 no  human deaths  and  remarkably few  human illnesses from  the
 agricultural  or  public health  uses  of  either  of  these chemicals.
 A  no-effect level of  50  mg/kg/day of  2,  4,  5-T  containing less
 than 1  ppm  dioxins  is  proposed as providing ample  protection
 for human  embryos  (114).

     The first recognized  incident  in  which significant
 poisoning resulted  from  the  improper disposal of waste
 residues containing TCDD (tetrachlorodibenzodioxin) was  in
 eastern Missouri.   In this incident, a salvage oil company
 sprayed waste-oil sludge on an arena at a  horse-breeding
 farm, to control dust.  Birds, cats, dogs,  and rodents were
 killed;  62 out of 85 horses became ill, and 48 died.   The
 horses had been exposed to the arena in the summer of 1971,
and they continued  to die as late as January 1974.  The  horses
showed chronic weight loss, loss  of hair, skin lesions,
dependent edema, intestinal colic, dark urine, gross  hematuria
 (the passage of blood in the urine), conjunctivitis,  joint
stiffness,  and laminitis (inflammation of one side of the
neural  arch of a vertebra).  In addition, the horses' feet


                               250

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were inflamed.  Human illness, although less severe, included
one case of hemorrahagic cystitis in a 6-yr-old girl who
played in the arena.  The soil of the arena contained 3.18
to 3.3 percent TCDD by weight and 2, 4, 5-tri chlorophenol
(TCP) and related chemicals  (662).

     Paraquat, a widely used bipyridyl herbicide, produces
a low-dose, chronic illness in rats, primarily manifested
by pulmonary fibrosis  (216).  Paraquat is also known to
cause severe lung damage in rats, leading to death.
Although it causes proliferation of fibroblasts, no
carcinogenic action has been demonstrated.  Taken orally,
paraquat causes ulceration in the digestive tract, diarrhea
and vomiting, renal damage, and jaundice.

Pesticidal Viruses

     Tinsley and Melnick(645), found some antibodies that
reacted with insect viruses  in domestic and wild animals and
in several laboratory workers handling insect viruses.
There is always a possibility that changes  in the patho-
genicity and specificity of  pesticidal insect viruses could
occur, causing a wider  spectrum of  host involvement.  No
collaborative research  programs on the in vitro  specificity
of insect viruses were  recommended  (645).

Fungicides

      In  Iraq during a  two-month period, 6,530 poisoning
victims were hospitalized, and 459 hospital  deaths  occurred.
The  source of the poisoning  was found  to  be homemade  bread
prepared  from seed  wheat treated with  methyl mercurial
fungicides (634).    In  another case,  diphenyl  (or  bi.phenyl )
poisoning  from fungicide  in a  Finnish  paper mill  was  reported
by  Seppalainen and  Hakkinen(573).    Workers were  employed in
areas of  the mill where the average  concentration of. diphenyl
measured  in  the air varied from 0.6  to 123.0 mg/m^.   The
workers  developed  EEC  abnormalities  that  were compatible  with
generalized  cerebral disturbance  (573).

Polychlorinated  Biphenyls  (PCB's)

      Relatively  high concentrations  of a  group  of  widely  used
 industrial  chemicals  known  as PCB's  have  been  found in  fish,
 birds,  and  man.  The widespread  presence  of  these PCB's  has
 tagged  them,like  DDT,  as truly  global  pollutants.   In fact,
 it has  been  speculated that  sunlight might  convert DDT  to
 PCB's.   PCB's  are  insoluble  in  water,  soluble  in fats and
 oils, and very  resistant to  chemical  and  biological degrada-
 tion.  Due to their solubility,  PCB's accumulate in the
 environment, especially in  aquatic  organisms and birds  (in


                               251

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 which cumulation factors  up to one  billion  may  be  reached)
 PCB's, like  DDT, can inhibit photosynthesis of  marine
 phytoplankton  and can kill  shrimp,  trout, minks, and  birds
 PCB's may be twice as effective as  DDT  in causing  thinning'of
 bird eggshells.

      In  1968,  over 1,000  people in  Japan suffered  from  a
 skin disease and from liver damage  caused by rice  oils.   The
 oil  was  heavily  contaminated with PCB's; however,  these
 effects  were not due to the PCB's but to a  highly  poisonous
 contaminant  -  chlorinated dibenzofurans.  This  contaminant
 is  found  in  some PCB's manufactured  in  other countries.

      To  date limited study  in  this  area indicates  that
 uncontaminated PCB's have a very low toxicity to man.
 According  to the Food and Drug  Administration,  the average
 PCB  concentration  in a normal  American  diet  is  only about
 10  percent of  the  strict safety  levels  set  in 1971 for  food,
 food packaging materials, and  animal feeds.

 SYNTHETIC/ORGANIC  CONTAMINANTS

      Recently diverse compounds  identified  in water supplies
 drawn  from the Mississippi  River have been  discovered in
 the  blood serum  of local  residents using the water supply.
 This  has created great concern  over chemicals found in
 drinking water.  The presence of small  amounts  of synthetic/
 organic chemicals  in treated reclaimed water has been
 recognized as a  potential  health hazard.

     The list of compounds  identified in drinking waters is
 rapidly growing  larger.   This is due primarily  to the
 continual introduction of new chemicals but  also to the
 development of sensitive analytical  techniques  that measure
 trace quantities of  the chemicals.   There  is very little
 evidence available concerning the relation  between  the
 presence of these compounds  in water and human disease.
 Information on classical  acute health effects of relatively
 toxic chemicals can  be obtained from physicians' manuals.
 However,  knowledge of the  chronic health effects associated
with long-term exposure to low-level concentrations of
chemical  substances  is not well documented.   The possibility
that cancer may result from  long-term exposure to low  con-
centrations of carcinogens  is of utmost  concern.

Carbon-Chloroform Extractables (CCE) and Carbon  Alcohol
Extractables  (CAET                  	'—

     The  Committee on Water  Quality  Criteria (672)   suggested
that absorbable organic  carbon in public water supply  sources
should not exceed the carbon chloroform  extractables  (CCE)


                              252

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level  of 0.7  mg/£.   (No  level  has  been  established  for carbon
alcohol  extractables  -  CAE).   The  establishment  of  this  level
was based upon  the  adverse  physiological  effects  of CCE  as well
as aesthetic  considerations.

     To date, laboratory testing  of the epidemiological  and
pathological  effects  of  trace  organics  has  been  restricted
to mice and fish.   Hueper and  Payne (306)  conducted a  study  of
mice that were  exposed  subcutaneously,  cutaneously, and  orally
to extracts of  CCE  and  CAE  obtained from both  raw and  finished
water supplies.   Results of this  study  indicated  that  these
extracts had  a  potential for carcinogenicity (see Table  99).
The cutaneous dose  used  in  the experiment was  one drop of  extract
every 2 weeks for 56 weeks  with 72 mice;  the subcutaneous  dose
was 2 to 4 mg every 2 weeks for 56 weeks with  72  mice; and the
oral dose administered  as 2 percent of  the raw powdered  food
was eaten ad  libitum by the animals for a 13-month  period  during
the study.  The control  group  consisted of 40  unexposed  mice.
No tumors were  observed  among  the 40 mice in the control
group or  among those exposed  orally.   Carcinogenic effects
in subcutaneous and  cutaneous  groups included one  papilloma
(a circumscribed overgrowth of the  papilla) of  the bladder;
four spindle-cell  sarcoma  (fusiform cell  tumor)  at the  site
of subcutaneous injection;  and leukemia,  lymphoma, or
reticulum-cel1 sarcoma  of  the  liver in all  other instances.
However,  it  is very  difficult  to  extrapolate  the experimental
data of  animals to humans.  Thus,  the  question  still  remains
as to whether such extracts would  cause  similar  abnormalities
in humans.

     Another experiment was conducted  to  investigate  the
toxicity  of  CCE and  CAE from  processed water  supplies (187)  .
A  total  of 5 mg of either  CCE  or  CAE was  introduced sub-
cutaneously  during the  first  20  days after birth of the
test mice.   No tumors were  found  to be induced  during  the
 period,  but  varied death rates of the  test animals were ob-
 served.   The studies were  conducted over a 1-yr period  using
 New  Orleans  drinking water supplies (187).

 Organohalides

      Occurrence  and  formation of organohalides  such as
 CHC13,  CHC^Br,  CHCIB^, and  CHBr3 were reported when water
 containing organic substances was chlorinated (41, 554).
 Of the  haloforms,  chloroform   (CHC13)  was reported as  the
 predominant  organohalide,  with concentrations ranging from
 54 yg/£ to 150 yg/£.  The  level  of risk for chloroform -
 estimated from  consideration  of the worst case  and for the
 expected cancer  site,  such as the liver -  might  be ex-
 trapolated to  account  for  up  to 40 percent of the observed
 liver  cancer.   The toxicity of chloroform has been well
 demonstrated in  lethal-dose studies.

                               253

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              TABLE 99 .  SUMMARY OF RESULTS OF INTRODUCING CCE AND CAE
                    FROM RAW AND FINISHED WATER INTO MICE (306)




ro
tn
•f*



Route of
Exposure
Subcutaneous
Cutaneous
Oral
Number of Tumors Produced/Animal Exoosed
Water Source
Raw Finished
CCE CAE CCE CAE
5/72 1/72 2/72 1/72
2/72 1/72 0/72 0/72
"* — - 0/40
-M 	 ~- 	 — 	 	 	
*  No test.

-------
     An LD50 (lethal  dose  -  50  percent)  value  ranging  from 89  to
35 mg/kg was observed by Tardiff  and  Deinzer  (636)  when  CCE
obtained from the  Kanawha  River in  West  Virginia  was  introduced
into mice via an  interperitoneal  route.   The  differences  among
these LDso values  was shown  to  be due to the  amount of chloroform
present in the extract,  indicating  the toxicity  of  chloroform.
The CAE obtained  from the  same  river  showed  an LDso of 84 mg/kg.
The LD5o for the  concentrated  organics from  Cincinnati  tap water
was shown to be 65 to 290  mg/kg.

     The same authors also  reported the  identification of 60
compounds from drinking  water.   Of  the compounds,  1  was  classified
as nontoxic; 14,  moderately  toxic;  16, very  toxic;  2,  extremely
toxic; and 27, unknown (74).   However, it is  difficult at this
time to determine  the relationships of the toxicities  of these
compounds in humans to the  level  of the  compounds present in
water and wastewater.

     Careful interpretation of the toxicity data,  such as
the 1050 value obtained from concentrated extracts, is
necessary when these values are  to be used to set  toxicity
levels in drinking water.

Polynuclear Aromatic Hydrocarbons  (PAH)

     Occurrence, formation, concentration, activity,  carcin-
ogenicity, and degradation of  polynuclear aromatic  hydro-
carbons  (PAH)  in water are well  documented  (17).

     Of  the PAH, 3,  4-benzpyrene has  been generally recognized
as the most potent carcinogen.   Minimal  carcinogenic  doses of
three of the most potent hydrocarbons in  susceptible  experi-
mental animals is shown in TablelOO  .


       TABLE 100 .  THE MINIMAL CARCINOGENIC  DOSE  FOR
    THREE OF THE MOST POTENT CARCINOGENIC HYDROCARBONS
         IN  SUSCEPTIBLE EXPERIMENTAL  ANIMALS  (716)

                                          Least  Amount  which
Carcinogen
3,4 - Benzpyrene
3,4 - Benzpyrene
1,2,5,6 - Dibenzanthracene
20 - Methyl cholanthrene

Animal
Mouse
Rat
Mouse
Mouse
Rat
Caused Cancer*
4.0 yg
50.0 yg
2.5 yg
4.5 yg
20.0 U
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Miscellaneous Organic Compounds

     A preliminary experiment was designed to study the
toxicity of organic compounds present in a secondary treat-
ment plant effluent.  Rats were supplied with filter-
sterilized effluent from an activated sludge plant as the
sole source of drinking water.  Two of the 10 rats developed
massive tumors.  Also, the exposed female rats developed
significantly smaller adrenal glands than the control rats
that were provided with the local water supply (496).

     An epidemiologic study on the toxicity of compounds
present in drinking water was cited by Andelman and Suess
(17).  This study indicated fewer cancer mortalities in a
London borough that was supplied with well water than in
boroughs supplied with river water.  This could mean that
the river water receives more carcinogenic waste material.

     Similar findings reported by Tromp (650)  showed that
areas using municipal water systems had Tower cancer death
rates than those using other systems.  However, the cancer
death rate was higher among areas that received municipal
water from a river than among those that received municipal
water from wells.

     When other factors such as food, air quality, and
individual habits (i.e., cigarette smoking) are considered,
the importance of trace carcinogens in water supplies may
not be significant.  However, several observations have been
made correlating water supply quality and cancer incidence.
For example,  Talbot and Harris (633)   established
a correlation between cancer mortality in white males and
water supply source, between mortality and urbanization, and
between mortality and income.  When occupational variables
are not considered, lung cancer mortality rates were found
to be correlated with surface water sources, but there were
no correlations found in other cancers.

Halogenated Hydrocarbons

     In a study that was designed to investigate the correla-
tion between levels of halogenated hydrocarbons in New
Orleans drinking water and levels of halogenated hydro-
carbons in blood plasma of individuals drinking the water,
13 halogenated hydrocarbons were isolated.  Researchers also
detected the presence of carbon tetrachloride and tetra-
chloroethylene (2 of the 13 compounds) in the pooled sera
of eight people.  It is probable that biomagnification was
involved if the chemicals in the plasma originated from the
drinking water (180).
                              256

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Low Molecular  Sulfurated  Hydrocarbons

     A case  history  study of  the  waterborne  goitrogens  and  their
role in the  etiology of  endemic goiter  was recently  reported  from
Colombia,  South  America  (229).  The  potential  presence  of  low
molecular  weight compounds (less  than  220),  such  as  sulfurated
hydrocarbons in  water and wastewater,  received  careful  evaluation.
The compounds  (sulfurated hydrocarbons)  were known  to  be  related
to the high  incidence of goiter among  children  and  were regarded
as waterborne  goitrogens.  The  study also  reported  a 10-fold
increase in  cancer of the thyroid where endemic goiter  was
observed (229).

BIOLOGICAL CONTAMINANTS

     Epidemics of waterborne  diseases  have largely  been elimi-
nated, due mainly to the advancement of sanitary  engineering,
enforcement  of public health  regulations,  and preventive  medical
practices; however,  waterborne  disease data  from  the last three
decades indicate that outbreaks  are  no longer on  the decline  in
the United States.  During the  25-yr period  from 1946 to  1970,
there were 358 recognized outbreaks  (72,358  individuals involved)
of disease or chemical poisoning  attributed  to contaminated
drinking water (145, 220).

     According to the reports of  the Center  for Disease Control
(221) during the past four years  (from 1972  to 1975), 105 water-
borne disease outbreaks  were  reported, involving 22,650 cases.
As shown in Table 101, in 1975,  24 waterborne disease outbreaks
were reported, involving 10,879 cases.

            TABLE 101.  WATERBORNE DISEASE OUTBREAKS
                      1972-1975 F AND W (145)
               1972      1973      1974      1975     Total
Outbreaks
Cases
29
1,638
24
1,720
28
8,413
24
10,879
105
22,650
      Table 102  shows  the  number of outbreaks and cases by
 etiology  and  type  of  water system.  The category with the most
 outbreaks Is  acute gastrointestinal  illness.  This category
 includes  outbreaks characterized by upper and/or lower gastro-
 intestinal  symptomatology for which no specific etiologic agent
 was  identified.   In previous years, these outbreaks were
 considered  sewage  poisoning.  One outbreak each was caused by
 giardiasis,  shigellosis,  enterotoxigenic E. coli, and hepatitis A.
 There were  no reported deaths associated wTth waterborne disease
 outbreaks in  1975   (221).

                                257

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      Most outbreaks involved  semipublic  (67 percent) and
 municipal (25 percent) water  systems;  some involved individual
 (8  percent) systems.  Outbreaks  attributed to water from muni-
 cipal  systems affected an average  of  1,218 persons; those
 attributed to semipublic systems  involved  221 persons; and those
 associated with individual water  systems  affected 13 persons.
 Of  those 16 outbreaks associated  with  semipublic water supplies,
 11  (69 percent) involved visitors  to  areas used mostly for
 recreational  purposes.


          TABLE 102.  WATERBORNE DISEASE OUTBREAKS, BY ETIOLOGY
                    AND TYPE OF  WATER SYSTEM, 1975 (221)

               Municipal      Semipublic       Individual       Total

            Outbreaks Cases  Outbreaks Cases Outbreaks  Cases  Outbreak? Cases

 Acute gastro-    4    7,300      13    2,460     —     ~      17    9,760
 intestinal
 illness
 Chemical         2      11      1      26                     3      37
 poisoning
 Giardiasis      —              ~             19        1       9

 Shigellosis     --     —        1      56     --     -        1      56

 Enterotoxi	        1    1,000     --     —        1    1,000
 genie £._ col i
 Hepatitis       —              —             1     17        1      17

   Total         6    7,311      16    3,542     2     26      24   10,879


     The  object  of  this  section is to  compile a  comprehensive
summary  of  research into  the  health effects of  biological  contami-
nants  in  wastewater treatment.  Diseases transmitted by water and
wastewater  largely  originate  in the intestinal  discharge of man
and/or animals.   These diseases are caused  by bacteria, viruses,
fungi, and  protozoan and  other parasites.

Protozoan  and  Other Parasites

     A number  of intestinal  parasite infections  can be introduced
into man  directly  from water  supplies  and  indirectly through
wastewater  discharges.  Under normal conditions,  the potable-water
route  of  infection  is  quite unimportant.   However, the reuse of
treated  waste  effluents  for potable purposes  requires  that  this
 problem  be  reexamined.

     Ascariasis   (a disease caused by  infection  with ascaris),
trichuriasis   (a disease  caused by infection  with trichuris), and

                               258

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hookworm diseases are some of the infections that originate from
direct soil  pollution by feces.   This pathway has been virtually
eliminated in the United States, due to the introduction of modern
sewage disposal  and water supply systems.   When there is a break-
down in sanitation, these diseases may reappear (699).

     Studies in  foreign areas affirm the relative unimportance of
public water supplies as a route of infection for intestinal
parasites.  A study by the World Health Organization  (WHO) in
Sudan, in which  a modern water supply was provided to one test
city, showed that parasitic infections were not decreased.  The
study indicated, instead, the need for sanitary waste disposal
facilities.   This finding was substantiated by the substitution
of a modern water supply system for an older system in Western
Transvaal.  The  substitution had no effect on the prevalence
of helminths among the Bantu population studies - children 7 to
16 years  (699).

     Amoebic dysentery (or amebiasis) appears to be the most
important parasitic disease associated with wastewater  in the
United States.  It is caused by Entamoeba his to1y t i c a ,  a  protozoan
Today, the prevalence rate of E. histolytica in the general popu-
lation of the United States is considered to be around  3  to 5
percent  (383).  The prevalence of the  intestinal protozoa varies
considerably in different population groups and  is generally
correlated with socioeconomic conditions.   Higher rates are
found in  areas of  poor sanitation and  in regions without  sewage
systems  and potable water.  Higher  rates are also noted in  groups
of people with poor personal hygiene  (e.g., patients  in institu-
tions for the mentally retarded).

      The  amoeba can form  small  cysts  (5 to  20  ym) with  a  specific
gravity  of about 1.06.   Each mature  cyst is capable  of  producing
four  motile amoebae.  The  cysts are  resistant  to adverse  environ-
mental conditions  and are excreted  with feces  into water  and/or
remain  in the human digestive tract to  become  vegetative  amoebae.
These amoebae multiply  and may  become  invasive,  causing erosion
of the  superficial mucous membranes.   They  may eventually invade
the  tissue with  consequent ulceration.

      The vegetative  forms do  not  survive outside  the  digestive
tract.   As with  most  parasitic  diseases, the  symptomatology
produced by  pathogenic  intestinal  protozoa  is  too  nonspecific  to
enable  the  physician  to  make  an accurate clinical  diagnosis.
In  1974,  there  were  2,743 reported  cases of amebiasis in  the
United  States (458),  because  of nonclinical  manifestations, the
actual  figure is  undoubtedly  considerably  higher.

      In  an  experiment  with  volunteers, it  has  been  demonstrated
that up  to  25 percent  could  be  infected by a  dose  containing  less
than 10  organisms  of  entamoeba; the remainder required a  minimal
dose of 10,000  organisms to  become infected.   However, as shown


                                259

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in Table 103, the infected volunteers did not manifest any signs
of illness.

     Giardia lamblia, a flagellated protozoan of the small
intestine, often implicated epidemiologically with drinking
water     is the etiological agent for giardiasis.  An outbreak
has recently been reported (460) in Rome, New York, where the
water supply could have been contaminated by untreated human
waste.  Another outbreak of giardiasis by G.  lamb!ia was reported
in September 1976 in Idaho.  The source was purported to be from
untreated surface water of an individual water system (290).

     Apparently, the cysts of GL_ lamb!ia survive in water and
remain infective for 16 days.  During 1969 to 1973, seven out-
breaks involving 193 people were reported in the United States.
During October 1954 to March 1955, there was a suspected water-
borne outbreak of 50,000 cases of giardiasis in Portland, Oregon.
The outbreak was not reported, because of the failure to isolate
the organism from the suspected water source (451).  Epidemic
giardiasis among American travelers to the Soviet Union has been
reported since 1970; the latest outbreak was reported in
October 1975 (460).   Sporadic single cases or occurrences of
giardiasis with recent exposure to untreated mountain or pond
water have been noted (457).   In an experiment where adult
humans were given challenge doses of Giardia lamblia, 76 to 100
percent infected with a dose containing 10 organisms did not
become ill.   Similar results were observed with doses containing
up to a million organisms (see Table 103).

     An outbreak of ascariasis occurred after World War I;
one out of every three surgical patients at a hospital in
Le Havre,  in the 2 yr following cessation of the war, was found
to have the disease (699).  Also, following World War II, a
40 percent incidence of ascariasis was reported in Darmstad
and was attributed to a widespread breakdown of sanitation
practices  that occurred in Germany during the latter part of
the war (699).

     In moderate climates, the human contribution of ova to
wastewater would appear to be no greater than 10 percent, but
may reach  30 percent in subtropical regions such as the southern
extremities of the United States.  The remainder of the ova is
of animal  origin.  Various authors have reported 59 to 80 worm
eggs/£ sewage (223).  The eggs are generally resistant to
environmental conditions, having a thick outer covering to
protect them against desiccation.   In one study, 90 percent of
ascaris ova was destroyed after 15 days at 29"C; the ova may
survive for up to 60 days at 40°C (223).

     Ova from the giant roundworm Ascari s 1umbri coides, the
pinworm Oxyuris vermicularis. the whipworm Tri churi s ' tri churia_,
the tapeworm Taenia saginata. and possibly the hookworm are


                               260

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                 TABLE 103 .   CLINICAL RESPONSE  OF ADULT  HUMANS  TO
                VARYING CHALLENGE DOSES  OF ENTERIC PATHOGENS  (88)
ORGANISM
(strain )
Shi gella
dysenteri ae
Challenge doses
10° 101 102 103 104 105 106 107 108 109 1010 1011

(1) (A-l)
(1) (M 131)

Shigella
flexneri (w)
(2a) -
(2a)

Vibrio
cholerae
inaba 569B
 (unbuffered)
inaba 569B
 (+NaHC03)

ogawa
(+NaHC03)

Salmonel la
(Zermat)vi
(Quailes)
                           ++
                                      ++++
++
                                                                     ++
                                             ++



-------
     TABLE  103.   (continued)
ORGANISM
(strain)
Salmonella
new port
Salmonel la
barei 1 ly
Salmonel la
Challenge doses
10° 101 102 103 TO4 105 106 107 108 1Q9 in^O lftll

+ ++
+ ++

    anatum(I)
           (II)
           (HI)
rsa            *
ro
    Salmonella
    meleagridis (I)
                (ID
                (HI)
                  *

    Salmonella
    derby

    SalmoneJ la
    pul loriTmd)
            (II)
            (III)
            (IV)

-------
ro
   TABLE 103.   (continued)
    ORGANISM
                                           Challenge doses
    (strain)
Escheri chia
coli(0111714)
TOt5":B4)
(06:H16)
(0124:K72:H-)
(0143:K?:H-'
(0144:K?:H-
(0148:H28)

Streptococcus
faecali s var.
1iquefaciens

Clostridi urn
perfringens.
type A (Heat-
resistant)

Clostridi um
pjsrf ri nqens
type A^tHeat
sensi tive)
               10'
10
10'
TO
10
10
                                          10
                                                                         10
                                                                           10
                                                                                 10
    Endamoeba
    coli
    Giardia
    Tambli a

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 TABLE 103.   (continued)
ORGANISM
(strain)
Chall
10° 101 TO2 103 104 TO5
enge doses
TO6 107 TO8 TO9
	 	
1010 1011
 agent
 (virus)l  ++
 ++      2  +++
        3  +

 Hepatitis
 virus A   +++
 (fecal    ++
 vi1trates)
de^optng niness? = 26~5°' +++ = 51'75' ++++ ' 76-100 Perce"t of volunteers

*  Refeeding trials of volunteers who mo before became infected by the same strain.

** 1,2,3 refers to serial passages of stool  filtrates.

( + ). Infections  without illness.

1 = cholera-like diarrhea.

-------
reported  to  be  present  in  wastewater (223).  Heavy infestations
of roundworms found  in  some  European cities are related to the
use of  night soil, which  is  also known to be responsible for
about 20  percent  of  the recurrent infections of amoebiasis and
hookworms  (237).

     Man  is  known to  be the  host and reservoir of A.  Tumbricoides.
whose ova are excreted  in  the  faces  of infected indTviduals.0~vT
of these  intestinal  parasites  require several  days before maturing
to an infective stage.   Under  the most favorable conditions,
ascarlds require  10  days to  mature;  trichurids, 21 days; and
hookworms, 6 days.   Hence, these parasites are unlikely to pose
health  threats  if the water  is  used  for drinking,  since they  would
be eliminated from the  human body before maturation.   However, use
of such water for food  processing,  garden watering, or simple
aesthetic activities  may require the effective removal  or destruc-
tion of the  parasites (699).

     Free-living  nematodes  are widely found in municipal water supplies.
Their potential as carriers  of enterococci, salmonella, and shigella has
been demonstrated  (699).  Although free-living nematodes are not important
as health threats  in conventional  waterworks practice,  their significance
in a reclaimed water situation needs  evaluation.

     Dracontiasis, or guinea worm infection, is a disease
primarily associated  with  poverty (especially  inadequate water
supplies  and wastewater treatment),  and is common in India and
West Africa.  Vector  species of Cyclops persisting in ponds
used for  drinking water must be controlled (usually by the use
of Abate  at  a concentration  of 1 mg/£).

     In summary,  it  may be stated that a large quantity of a
variety of ova  from  parasitic  worms may be present in wastewater,
and that  the ova  possess  a high degree of resistance to many
environmental stresses.

Fungi

     Candida albjcans,  a  pathogenic, yeastlike  fungus,  is an
asporogenous (non-spore-forming) yeast that develops pseudohyphae
(a kind of filamentous  structure).  Large, round, thick-walled
chlamydospores  -  the morphological  characteristic of the  genus
Candida -  are frequently,  though not always,  present in waste-
water.

     c- albicans  has been found  in  the feces  and  skin of several
animaV~species  other than man.   The fungus rarely occurs in
soil.   The prevalence of Candida  in feces in  different regions  of
the United  States varies from  19.3  to 44.6 percent of the total
population (323).   Seventy percent  of the inhabitants of Baghdad
have the  fungus in their feces.   Another important infective
                                265

-------
area in the human body is the female vagina;  43 percent  of  the
female population in the United States are carriers (323) .

     C. albicans may cause oral thrush, cornea! ulcers,  and
other ocular infections.  One survey analyzed 20 weekly  samples
collected at three stations on the North Shore of Great  South
Bay, Long Island.  It was reported that the estuarine  water
samples contained between 1,000 to 11,000 or  more cells/£(323).
These results are shown in Table 104.

       TABLE 104.  AVERAGE VALUES  FOR C. ALBICANS, COLIFORM
    AND FECAL COLIFORM  COUNTS AND TOC  (TOTAL ORGANIC CARBON)
         DETERMINATIONS  IN THE  ESTUARINE WATER SAMPLES,
                  LONG  ISLAND,  NEW YORK  (323)


Estuari ne
Stations
Station 1
Station 2
Station 3

C. albicans
cells/.£
4,245
4,003
9,555
Col iform
Total
MPN/100 ml
338
298
1,962
Col iform
Fecal
MPN/100 ml
33
12
490.5

TOC
mg/£
8
8.4
8.7

     This fungus retained an infectivity and pathogenicity to
mice after  it was exposed to sea water for eight weeks  (323).
In the open ocean, there is a concentration of 200 to 300 fungal
cells/£; in moderately contaminated beach areas, there  are
levels of 10,000 to 20,000 cells/£J and in heavily contaminated
estuaries,  up to 100,000 eel ls/£(323) .   The overall trend was
a gradual increase in concentrations during summer months, from
June to September, after which the concentration declined (323).

Bacteria

Salmonellosis--
     A wide variety of species that are pathogenic to man and
animals belongs to the genus Salmonella.  Water and food, as
well as personal contact, are the main routes for transmission
of the species from man to man.

     Among  the three distinct forms of salmonellosis in man,
typhoid fever - caused by S_^ typhj -  is the most severe
enteric fever form, and man is the only host.  Salmonella
septicemia, most commonly caused by S. choleraesuis. is
relatively  rare.  This bacteria  is not particularly common in
humans, but has a predilection for swine.  Salmonella are most
commonly encountered in acute gastroenteritis.  Serotypes (types
based on antibodies) in excess of 1,500 have been identified.
Most, in contrast to S. typhi, are not host specific.


                              266

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     The death rate,  due  to  typhoid  fever  in  the  United States
in 1900, was 31.3/100,000 population;  however,  at  present, death
due to this disease is practically  nonexistent, as  shown in
Table 105 (164,  308).

         TABLE 105.  U.S. MORTALITY  FROM SELECTED  CAUSES
                RELATED TO WATER POLLUTION (164)

Cau
Fyphoi
se
d
of Death
& paratyphoid
1920
7.6
Death
1930 1
4.8
Rate
940
1.1
per 100
1950
0.1
,000
1960
0.0
1967
0.0
fever

Dysentery

Gastritis, duodenitis,
enteritis, & colitis
 4.0   2.8    1.9    0.6    0.2    0.1

53.7  26.0   10.3    5.1    4.4    3.8
     Relatively few outbreaks of typhoid fever and salmonellosis
associated with drinking water were reported in the United States
during 1971 to 1973(220, 448).   The reported isolation rates
for humans in the United States in 1972 was 12.5/100,000; the
fatality rate between 1962 and 1972 was 0.43 percent, mostly
among the very young and very old.

     In 1974, 23,833 isolations of salmonella were reported to
the Center for Disease Control, a decrease of 2,855 cases
(10.7 percent) from the previous year.  As in 1973, S. typhimurium
(30.8 percent), S. newport (6.9 percent), and S. enteritides
(6.0 percent) were the first, second, and thircTmost commonly
isolated serotypes, respectively  ( 563).  The annual incidence of
reported human isolations of salmonella has remained relatively
constant since 1963  (563).
The seasonal incidence for the period from 1967 to 1974 shows
a consistent pattern, with the greatest number of isolations
reported in July through November, and the fewest reported in
February through April (563).

     The ages of infected persons reveal that 66.8 percent of
the 17,229 isolations was from persons less than 20 yr of age.
Similarly, this age group showed  the highest  infection incidence
for the years from 1963 through 1973  (563).
     Several serotypes  (e.g., S. weltevreden
S. os 11o in Hawaii; S. newport and S. javiana
states! have definite regional patterns, for
not clear.
                     S. panama. and
,  5^_ £
 in  th
                           southern
                    reasons  that are
                               267

-------
     from 1962 to 1974, 143 deaths were reported among the 34,291
persons involved in 499 outbreaks.  This resulted in  a  case-
fatality ratio of 0.42 percent.

     In 1974, in 18 of the 34 outbreaks of salmonellosis  (involv-
ing a total Of 4,011 persons), 5 outbreaks were caused  by contami-
nated poultry, 5 by beef or beef  products, and  3 by dairy products,
In 6 of these outbreaks, person-to-person transmission was thought
to be responsible; none was reported to be transmitted by water.
In 1§73, 3 typhoid outbreaks  (totalling 217 cases) and 1 out-
break of salmonellosis (3 cases)  occured  in semipublic or
individual water supplies.  In  1974, an outbreak involving several
hundred people on a cruise was  reported;  epidemiologic investiga-
tion failed to clearly implicate  either food or water.   Three
epidemiologic investigations  of turtle-associated salmonellosis
were also found in thfe 1iterature(144).

     According to experimental  data, the  dose  required to bring
about human cases of typhoid  fever is  surprisingly high  (300).
Human volunteers were challenged  with  various  doses of
Salmonella typji_j_.   The results are summarized  in Table  106.


               TABLE .ioe.  RELATION OF DOSAGE  OF
                 IL. TYPHOSA TO  DISEASE  (300)


Number of Viabie CellsTotal  VolunteersNumber with  Disease
     S_^ typhosa            Challenged
109
lb8
107
105
103
42
9
32
116
14
40 (95%)
8 (89%)
16 (50%)
32 (28%)
0 (-- )
     With the salmonella species isolated from spray-dried eggs,
human volunteers were challenged orally; the results are
Summarized in Table 107.  Existence of varying degrees of
virulence among the species and strains are shown.  Similar
results are shown in Table 103.
                              268

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       TABLE 107 .   DOSE  OF  VARIOUS  SPECIES  AND  STRAINS  OF
    SALMONELLA THAT CAUSED  DISEASE  IN  HUMAN VOLUNTEERS  (142)

     Salmonella                        Dose at which 50% or More
   Species/Strain                       Develop Clinical Disease
S.  meleagridis I50,000,000
S.  meleagridis II                          41,000,000
S.  meleagridis III                       >10,000,000
S.  anatum I                                '  860,000
S.  anatum II                               67,000,000
S.  anatum III                               4,700,000
S.  newport                                 1,350,000
S.  derby                                  15,000,000
S.  bareilly                                1,700,000
S.  pullorum I                         >1 ,795,000,000
S.  pullorum II                          >163,000,000
S.  pulloram III                       >1,295,000,000
S.  pullorum IV                         1,28(0,000,000
 Shigellosis--
      Shigella  cause  bacillary  dysentery  in  man  and  in  higher
 apes.   Although  person-to-person  transmission  is  the  predominant
 mode  of spreading  shigellosis, waterborne outbreaks have  played
 a  significant  role in  the  overall  epidemiology  of the  disease
 in the  United  States(579,  612).     In  1975,  14,757 shigella
 isolations  from  humans were  reported  to  the Center  for Disease
 Control (CDC).   This was  a decrease of  24.0 percent from  the
 19,420  isolations  reported in  1974 (580).    Utilizing  population
 estimates for  July 1,  1975,  approximately 69.2  isolations were
 reported for each  million  population  of  the United  States in  1975.
 Shigella sonnei  (60.3   percent )  was  the most common  etiological
 agent in all these cases,  followed by S. flexneri (38.2 percent).
 Between January  17 and March 15,  1974,  approximately  1,200 cases
 of acute gastrointestinal  illness occurred  in Richmond Heights,
 Florida.  The  outbreak was caused by a  failure in the chlorination
 process of well  water, which allowed insufficiently chlorinated
                                269

-------
water from a contaminated well  (located near a church's septic
tank) to be distributed to the  community (144).

     Most instances of Shigella-induced illnesses reported in the
past several years have involved small wells, temporary break-
downs of chlorination systems in water supply, and swimming in
waters contaminated with sewage.  The isolation rate in the United
States is approximately 15/1,000,000 population.   Up to 25 per-
cent of adult humans may be infected and show clinical  response
to Shigella dysenteriae doses of 10 cells; 25 to  50 percent, to
doses of 100 eel Is; and up to 100 percent, to doses of  10^ cells
(see Table 103).  These results indicate that it  would  take
smaller doses to show clinical response for shigella than it
would take to show response for salmonella.


Cholera--
     Cholera, which is fully  controlled  in the  United States,
has created a major global  public health problem  in India, Italy,
Portugal, and many other countries.  In the United States, only
one case (in the Gulf Coast town of Port Lavaca,  Texas) has
been reported since 1911.   Transmission was associated  with a
well that was contaminated  by leachate from a septic tank system.

     The etiological  agent  of cholera is Vibrio chplerae, Biotype
El Tor, Serotype Inaba or  Ogawa.  Man is the only known natural
host, and,  since a prolonged carrier state is uncommon, the
disease must be maintained  by an unbroken chain of mild, subtle
infections.   Cholera  is a  serious disease, similar to typhoid
fever but more rapid  in onset, more virulent, and more  often
fatal.   Death rates of 25  to 85 percent are commonly reported
(142).

     The primary means of  cholera transmission is the drinking
of contaminated water.  Also associated with cholera is the
eating  of fish caught in contaminated waters.  In the event that
imported cases occurred in  the United States, it  is felt that
the risk of spread would be minimal  because of modern, indus-
trialized sanitary engineering  as well as responsible  medical
therapy.   It is also  reported that vaccination is not needed
to control  imported cases  or outbreaks that may occur in the
United  States (144).

     The minimum doses of  vibrio that cause clinical symptoms
in adult humans may vary (depending upon the strains of vibrio
that are used) from 103 cells (in up to 50 percent of the
individuals) to 105 cells  (in up to 75 percent of the individuals),
as shown in Table 103.
                              270

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Gastroenteritis--
     There are many reports of waterborne gastroenteritis  of
unknown etiology in which bacterial  infections  are suspected.
These include outbreaks characterized by nausea,  vomiting,
diarrhea, and fever, for which no specific etiologic agent
could be identified.

     An epidemiological study of the impact of  wastewater
pollution on marine bathing beaches  was conducted during the
summers of 1973 and 1974 at the Coney Island and  Rockaways
beaches in New York (95).    A statistically significant finding
was observed:  the rate of gastrointestinal symptoms among
swimmers compared to nonswimmers was higher at  Coney Island,
where the densities of the indicative organisms such as E. coli
and fecal streptococci were significantly higher  than the
densities at Rockaways Beach (Tables 108 and 109 ).  It was
concluded that there were measurable health effects associated
with sewage  polluted waters  (95).

     In 1971, a waterborne gastroenteritis outbreak was
reported  in  Pico Rivera, California, in which 11,000 residents
became  ill with diarrhea and abdominal  cramps.   No pathogens
were isolated from  any cases.  The  source of water was
responsible  for the outbreak; chlorination at the reservoir had
been interrupted when  the  chlorine  supply was exhausted.  One
of  the  major outbreaks involving over  1,000  persons occurred
at  Crater Lake  National  Park, Oregon,  in  July 1975.  The
illness was  reported  to  be associated  with sewage-contaminated
water  (459).  Enterotoxigenic E. col i ,  Serotype 06:H16, was
isolated  from ill  park residents and from  the park's water
supply  (221) .

     It was  noted  that  the attack rate of  acute  "summer diarrhea"
on  the  Fort  Apache  Reservation,  Arizona,  during  1971,  rose
simultaneously  with rainfall, temperature,  and bacterial
contamination of  water  sources (703).    Nonenteropathogenic
E.  coli  capable of  producing  enterotoxin  was isolated.

     In the  study  of  clinical response of  adult  humans  to
challenge doses of  E.  coli,  it  has  been demonstrated  that very
large  doses  of  cells  (about  108) would be necessary  to  show
clinical  response  in  75  percent  of  the individuals  tested
 (Table  103  ).   With the  E. coli  strain of 0111:84,  doses  of
only 106  cells  were necessary  for a similar  response.   However,
 it  should be noted  that the  digestive  tract  in most individuals
 is  populated by normal  flora,  of which E.  coli is the most
 abundant and most characteristic; about 10^/g  of feces is
 common(44) .
                               271

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N)
-vl
K)
                   TABLE 108.  MEAN INDICATOR DENSITIES AT THE CONEY ISLAND
               AND ROCKAWAYS BEACHES,  NEW YORK, DURING 1973 AND 1974 TRIALS  (95).
Indicator
Total coliforms
Fecal coliforms
Escherichia coli
Klebsiella
Enterobacter-cltrobacter
Fecal streptococci
Pseudomonas aeruginosj^
Aeromonas hydrophila
Vibrio parahaemol yticus

Log Mean Recovery/100 ml
1973
Coney Isl .
983*
165*
174*
112*
530*
91.2
30.4
25.3
ND
Rockaways
39.8
21 .5
24.8
13.7
11.1
21 .8
6.5
26.5
ND
1974
Coney Isl .
1213*
565*
15.3*
59.2*
434
16.4*
45.8*
9.6
54.5
Rockaways
43.2
28.4
2.4
3.5
6.6
3.5
3.1
4.9
32.8
     *Significantly different at 95 percent confidence  level.

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                   TABLE 109 .   SYMPTOM  RATES  IN  PERCENT AT CONEY  ISLAND AND ROCKAWAYS BEACHES,
                                    NEW  YORK.  DURING  1973 AND 1974 TRIALS(95)
Symptom
Group
Rates in Percent for Symptom


1973
Coney Island
S
NS
X
Rockaways
S NS


X
Groups in
1974
Coney Island
S
NS
X
Rockaways
S NS x
NJ
N
Resp.
G.I.
Other
"Severe"
474
12.9
7.2a
9.9
5.9
167
10.2
2.4
6.6
4.2

2.7
4.8
3.3
1.7
484
18.0ab
8.1
9.1
6.0
197
11.7
4.6
8.6
5.6

6.3
3.5
0.5
0.4
1961
7.2
4.2a
7.3
3.8
1185
6.4
2.6
6.7
2.9

0.8
1.6
0.6
0.9
2767
8.3
3.9
8.6
3.0
2156
7.8
3.5
7.7
2.6

0.5
0.4
0.9
0.4
       a  Significantly (P = 0.5)  higher than nonswimmers.
       b  Significantly (P = 0.5)  higher than other beach.
       N-sample size;  S-swimmers; NS-nonswimmers;x-difference
      GI - gastrointestinal; Resp. - respiratory

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Leptosplrosis--
     Etiological agents of 1eptospirosis  (an  infection caused
by leptospira) constitute approximately  150  different serotypes
categorized on the basis of their agglutinogenic  properties
(383).   The pathogenic serotypes are otherwise  indistinguishable
by morphology or biochemical  activity.

     Recognition of two species, Leptospira  interrogans and
L._ biflexa, has been proposed for the so-called  pathogenic and
saprophytic leptospires, respectively (383).

     Generally, 1eptospirosis, typically a disease of animals,
has been regarded as an occupational disease that occurs
primarily in workers associated with wastewater, rice,  sugar
cane, farms, and slaughter yards.  The disease is transmitted
to man by direct contact or via water contaminated by urine
from infected wild and domestic animals.   Leptospirosis  is
endemic in some parts of the world.  However, 11 outbreaks in
nonendemic areas during 1939 to 1959 were associated with
swimming or wading in contaminated water  (144,  283),  indicating
the potential for contacting the disease as  a result of
recreational activity.

     At the same time, leptospirosis has become a more  recognizable
human health problem in recent years, because of better  identifi-
cation of symptoms and improved methods of diagnosis.  In rural
populations in France, the percentage of infection by source was
as follows:  water or mud, 21 percent; animals, 53 percent; and
water and animals, 25 percent.  In nonrural  populations,  how-
ever, 80 percent of the infections was acquired by contact
with contaminated water (144).    It was also noted that  sub-
clinical leptospirosis in humans was not infrequent and  may be
a significant public health hazard (144).    Information  on the
infective dose of leptospira to humans is not available  from the
literature surveyed.  Leptospira can apparently penetrate intact
skin, assisted by cuts, abrasions, and immersion.  Incidences of
infection from swimming also suggested penetration via  the
mucous membranes of the mouth or nasopharynx (144) .   The nesting
site of leptospires in natural hosts is the lumen of nephritic
tubules, from which they are shed into the urine   (144).  Patho-
genic leptospires can survive for three or more months  in neutral
or slightly alkaline waters, but do not persist in brackish or
acidic water (144).    In 1975, two outbreaks of leptospirosis
were attributed to swimming in contaminated surface water.  Seven
children in Tennessee developed infection with L. interrogans
serotype grippotyphosa after swimming in a small local  stream.
Two persons in Louisiana became infected with leptospires of the
serotype icterohaemorrhagiae after bathing in a man-made lake  (221)
                              274

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Tuberculosis--
     The possibility that tuberculosis  may be  transmitted  by
sewage has frequently been considered  in  connection  with  the
disposal of wastewaters from hospitals, tuberculosis sanitaria,
dairies, and slaughter houses; the possibility has  even  been
considered in connection with domestic  sewage  in  general.
Concern has been expressed about the danger of human and  animal
infection, particularly where these waters are reused (266).

     The presence of mycobacteria in wastewater has been
extensively studied since around 1900 - the time  of the  first
findings of the bacteria in feces (223).   The  recovery of
Mycobacterium tuberculosis (the bacteria that  cause tuberculosis)
is difficult, even from favorable sources such as sputum;
recovery from sewage is much more difficult because of the
presence of other bacteria.

     The tubercle bacilli are present  in the  sputum and feces
of tuberculosis patients.  The wastes  from institutions that
treat  the patients will almost always  contain large numbers
(4 x 105 to 10//£ ) of tubercle bacilli (266).   Significant
numbers (about 3/£ in the effluent of  a  plant producing about
7,600  gpd of milk) of virulent tubercle  bacilli  are  also  found
in the wastes from some dairies.  A cow  suffering with tuber-
culosis of the udders discharges  about 1.5 x  10** tubercle
bacilli/day (266).  M. balnei , which causes granuloma, may be
present in chlorinate~d~ water  used for  swimming pools  (295)
of the data on survival of tubercle bacilli in sewage Indicate
that,  under laboratory conditions, the bacteria  can be infective
for 6  months  in sewage and for up to 24  months in  feces  (266).

     Contaminated water can  produce typical tuberculosis  in
humans  in  some instances.  The first clear-cut cases  of  human
infection were reported  in  1947.  From 1947 to 1953,  nine cases
of tuberculosis were described in humans who  aspirated polluted
water  into  their  lungs after  swimming  and  nearly drowning in
contaminated  water (266).

     There  were not  much  data available  in  the literature on
the  infectious dose  to  humans of  tubercle  bacilli  in wastewater.
In an  experiment  with  guinea  pigs,  it  was  reported  that  80 per-
cent of the  animals  contracted  the  disease  when  they were fed
with grass  that had  been  sprayed  with  more  than  4  x 106  tubercle
bacilli.   Calves  that  had  been  similarly fed  also  succumbed  (266)

     The  majority of studies  carried out on mycobacteria  has
focused on  the  presence  of  M. tuberculosis  in sanitarium  wastes.
These  studies may not  providT a  realistic  picture  of the  danger
of  infection  from contaminated  water.
                               275

-------
     The potential  health  hazards  of  M.  tuberculosis being
transmitted  through sanitarium  wastewaters,  to drinking supplies,
and back to  man  in  general  appears  to  be  quite remote.

Viruses--
     In the  past,  transmission  of  waterborne  viral diseases was
rarely recognized,  due  largely  to  lack  of sensitive virus-detection
methods and  precise quantification.   With improved techniques for
concentrating  viruses from  large water  samples,  increasing
occurrences  of viruses  in water and wastewaters  have been reported.
Viral  transmission  through  water may  take place  in various ways:
bathing in  contaminated  water,  eating  contaminated seafoods,
drinking from untreated or improperly treated water sources,
or contacting contaminated waters.  Enteric viruses have been
investigated with greater emphasis than  any other group of
viruses, mainly because any virus excreted in the feces and
capable of producing infection when ingested is theoretically
transmissible by water.  The human enteric viruses and the
diseases associated with them are listed  in Tables 110 and 111.
              TABLE 110.  THE HUMAN ENTERIC VIRUSES
          AND THE DISEASES ASSOCIATED WITH THEM (142)
  Virus Subgroup
No. of
 Types
       Disease
Polio virus
Coxsackie virus
  Group A
  Group B
ECHO virus



Infectious hepatitis

Reovirus


Adenovi rus
  26
   6
  34
   K?)

   3
  32
           paralytic poliomyelitis,
           aseptic meningitis
herpangina, aseptic meningitis,
paralysis pleurodynia,
aseptic meningitis, acute
Infantile myocarditis

aseptic meningitis, rash and
fever, diarrhea! disease,
respiratory illnesses

infectious hepatitis

fever, respiratory infections,
diarrhea

respiratory and eye infections
                               276

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                           TABLE 111 .   THE HUMAN ENTERIC VIRUSES  THAT CAN BE WATERBORNE
                              AND KNOWN DISEASES ASSOCIATED WITH  THESE VIRUSES (637)
       Group
           No. of
          Types or
Subgroup  Subtypes
Disease Entities Associated
    with These Viruses
Pathologic Changes In
      Patients
  Organs Where
Virus Multiplies
    Enterovlrus  Pol1ov1rus
                 ECHO virus    34
r\>
                     Muscular paralysis


                     Aseptic meningitis

                     Febrile episode

                     Aseptic meningitis

                     Muscular paralysis


                     Gulllain-Barre's Syndrome

                     Exanthem

                     Respiratory diseases




                     Diarrhea

                     Epidemic myalgia
                     Pericarditis & myocarditis


                     Hepatitis
                               Destruction  of motor
                                neurons

                               Inflammation of
                                meninges from virus
                               Vlremia and  viral
                                multiplication
                               Inflammation of
                                meninges from virus
                               Destruction  of
                                motor neurons

                               Destruction  of
                               motor neurons
                               Dilation and rupture
                               of blood vessels
                              Viral Invasion of
                               parenchymiatous of
                               respiratory trarcts
                               and secondary Inflam-
                               matory responses
                              Destruction of
                               intestinal  bacteria
                              Not well  known
                              Viral invasion of
                               cells with secondary
                               responses
                              Viral invasion of
                               cells with secondary
                               responses
                         Intestinal  mucosa
                          spinal  cord,
                          brain  stem
                         Meninges

                         Intestinal  mucosa
                          and  lymph
                         Meninges

                         Intestinal  mucosa
                          spinal  cord,
                          brain stem
                         Spinal cord

                         Skin

                         Respiratory tracts
                         and  lungs
                                                                                              Intestine


                                                                                              Perfcardial  and
                                                                                               myocardial  tissue

                                                                                             liver parenchyma

-------
     TABLE 111.    (continued)
        Group
           No. of
          Types or
Subgroup  Subtypes
Disease Entitles Associated
    with These Viruses
Pathologic Changes in
      Patients
  Organs Where
Virus Multiplies
     Enterovirus  Coxsackie
     (cont'd)      virus
N>
^1
00
                     B
             >24      Herpangina


                      Acute  lymphatic  pharyngitis


                      Aseptic  meningitis

                      Muscular paralysis


                      Hand-fcot-mouth  disease



                      Respiratory disease




                      Infantile diarrhea

                      Hepatitis

                      Pericarditis & myocarditis

               6      Pleurodynia

                      Aseptic  meningitis
                      Muscular paralysis
                               Viral invasion of
                                mucosa with secondary
                                inflammatory responses
                               Viral invasion of
                                mucosa with secondary
                                inflammatory responses
                               Inflammation of
                                meninges from virus
                               Destruction of motor
                                neurons

                               Viral invasion of
                                cells of skin of
                                hands and feet and
                                mucosa of mouth
                               Viral invasion of
                                parenchyma of
                                respiratory tracts
                                and secondary inflam-
                                matory responses
                               Viral invasion of
                                cells of mucosa
                               Viral invasion of
                                liver cells
                               Same as before

                               Viral invasion of
                                muscle cells
                               Same as before
                               Same as before
                        Mouth
                        Lymph nodes
                         and pharynx

                        Meninges

                        Intestinal mucosa
                         spinal cord,
                         brain stem
                        Skin of hands
                         and feet and
                         much of mouth

                        Respiratory
                         tracts and
                         lungs
                        Intestinal
                         mucosa
                        Parenchyma cells
                         of liver
                        Same as before

                        Intercostal
                         muscles
                        Same as before
                        Same as before

-------
       TABLE 111.    (continued)
          Group
           No.  of
          Types or   Disease Entitles Associated
Subgroup  Subtypes       with These Viruses
                                Pathologic Changes  in
                                      Patients
       Enterovirus  Coxsackie
       (cont'd)      virus B
                    (cont'd)
ro
•vj
to
      Reovirus

      Adenovirus
            6

           31
     Hepatitis
          >2
                      Meningoencephalitis

                      Pericarditis, endocarditis,
                      mycarditis
                      Respiratory diseases
                      Hepatitis or rash
                      Spontaneous abortion

                      Insulin-dependent diabetes
                     Congenital heart anomalies
 Not well  known

 Respiratory diseases
 Acute conjunctivitis
Acute appendicitis

Intussusception

Sub acute thyroiditis

Sarcoma in hamsters

Infectious hepatitis
                            Organs Where
                          Virus Multiplies
 Viral invasional
  invasion of cells
 Same as before

 Same as before
 Same as before
 Viral invasion of
  vascular cells (?)
 Viral invasion of
  insulin producing
  cells
 Viral invasion of
  muscle  cells

 Not  well  known

 Same as  before
 Viral  invasion of
 cells and secondary
 inflammatory  responses
 Viral  invasion of
 mucosa cells
 Viral  invasion of
 lymph nodes (?)
Viral invasion of
 parenchyma cells
Transformation of
 cells
Invasion of paren-
 chyma cells
                                                        Meninges and
                                                         brains
                                                        Same as before

                                                        Same as before
                                                        Same as before
                                                        Placenta

                                                        Langerhans cells
                                                         of  pancreases

                                                        Developing heart
 Same as  before
 Conjunctival
 cells and blood
 vessels
 Append1a and
 lymph nodes
 Intestinal lymph
 nodes (?)
Thyroid

Muscle cells

Liver

-------
     TABLE 111.    (continued)
        Group
           No.  of
          Types or
Subgroup  Subtypes
Disease Entitles Associated
    with These Viruses
Pathologic Changes in
      Patients
  Organs Where
Virus Multiplies
Hepatitis
(cont'd)
Serus hepatitis
Down's Syndrome
Invasion of paren-
chyma cells
Invasion of cells
Liver
Frontal lobe
                                                                                              of brain,
                                                                                              muscle,  bones
K>
00
O

-------
Infectious Hepatitis--
     Apart from theoretical  considerations,  there  are  very  few
viruses for which epidemiological  evidence  suggests  transmission
by water.   Infectious  hepatitis  (hepatitis  A)  is  the only disease
caused by  an agent having  the  characteristics  of  a virus for
which evidence of waterborne transmission  has  been accepted by
all workers in the field(468).   Therefore,  it is  regarded  as  the
viral disease of greatest  importance in  wastewater.

     In 1973 alone, a  total  of 59,200 cases of viral hepatitis A,
 B, and a  type unspecified were  reported (221).   In 1974,  a total
of 59,340  cases of viral  hepatitis -  hepatitis A,  B, and  type
unspecified -  were reported to  CDC.  This represents  a rate of
28.1 cases/100,000 population, approximately the same  rate  as for
1973.  Since 1971, 1974 is the first year to have shown rate
increases for two quarters; the  increase in cases began in the
fourth quarter of 1973.  The seasonal variation noted in the
1950s  and early 1960s was not seen  in 1974.  The  48,709 cases
of acute  hepatitis A and hepatitis, type unspecified, constituted
82.1 percent of the total  cases  of  viral hepatitis  reported in
1974  (291).   Waterborne outbreaks of hepatitis A  continue  to
occur  in  the United States.  From 1971 to 1973, these documented
outbreaks were associated with contaminated drinking water from
either municipal, semipublic, or  individual water systems (144,
448).  Use  of contaminated spring or groundwater  without proper
treatment or disinfection, and back-siphonage of  contaminated
water  into  the distribution system  were reported  to be the
causes of the outbreaks.  The majority of documented  hepatitis A
outbreaks  in municipal water systems in the United  States  between
1946  and  1971 occurred as a result  of distribution  system
contamination, primarily through  cross connections  and back-
siphonage.

      Two  outbreaks of  shellfish-associated  hepatitis  involving
285  cases were reported in  1973(221).   Both  outbreaks - one
in Georgia  and the other in Texas  - were  associated with the
eating of raw  oysters.  Epidemiologic evidence  suggested that
two  particular bays contaminated  by flooding  were the  source  of
the  contaminated  oysters.

      A recent  hepatitis outbreak  of 14 cases  was  reported  to
be associated  with swimming in a  grossly  contaminated  lake in
North  Carolina,  and with  ingesting  water  from that  lake.   This
is the first time that such a definite case has  been  made  for
the  potential  of contracting  this  disease  while  swimming in
sewage-polluted  water*         The  probable fecal-oral trans-
mission of infectious  hepatitis made the  waterborne route
possible.   This  mode  of transmission was  vividly  illustrated
by several  large epidemics  that  took place  in 1955  to  1956,
especially in India where  28,745  cases  occurred  (468).
                               281

-------
    As far as the magnitude of waterborne infectious hepatitis
is concerned, the water route still only accounts for up to
1 percent of reported cases at any time for which information
is available (468).

    Despite the increased interest and concern in infectious
hepatitis, its infectious agent has not yet been isolated and
cultured.  One recent report (212) using microscopic techniques
was able to show the presence of viruslike particles,  immunolo-
gically distinct from hepatitis B, in infected stools.

Poliomyelitis--
    The infectivity of feces from persons with poliomyelitis
and the characteristic fecal excretion of the diseased  persons
have  been documented for years.   The  polio virus has been sought
and detected in sewage.  Accordingly, the water  route  of  trans-
mission has been implicated in several  outbreaks of poliomyelitis
(see  Table 112).  Many cases of epidemics of  poliomyelitis were
attributed to waterborne transmission through contaminated or
untreated water, but the evidence  is  not  sufficient.   It  appears
that  water transmission of  the polio  virus may  be a rare  occurrence
in the United States, but common  in  parts of  the world  lacking
adequate sanitary facilities.  Six of the outbreaks attributed
to drinking water occurred  in Sweden  during  the  1930s  and 1940s
(468)  and led to the early  recognition  of the importance  of the
fecal-oral route in poliomyelitis.


Viral  Gastroenteritis--
      When a recognized pathogen cannot  be isolated  in  cases
of gastroenteritis and diarrhea,  the  term viral  is  often  used
to describe the symptoms.   It is  quite  possible  that forms
of gastroenteritis and diarrhea transmissible from  person to
person are due to viruses.

      Gastroenteritis and diarrhea! disease are  believed  to
have  accounted for approximately  60  percent  of  all  epidemics
of waterborne diseases throughout  history.   The  number  of
these cases that was due to viral  agents  is  not  known;  if,
however, only a small portion of  the  cases was  due  to  viral
agents, this number would still be quite  substantial.

     A viruslike particle,  similar in appearance but immuno-
logically distinct from the hepatitis A,  has  been reported to
be associated with an acute infectious  nonbacterial gastro-
enteritis  (341).  Shellfish-associated  gastroenteritis  has also
been reported (177).
                               282

-------
ro
CO
                 TABLE 112.   PUBLISHED REPORTS OF POLIOMYELITIS ATTRIBUTED TO
                              CONTAMINATED DRINKING WATER(463)
No.
1
2
3
4
5
6
7
8
Yr of
occurrence
1913(?)-39
1944
1944
1948
1948
1949
1952
1953
References
Spaak, 1941
Kling, 1947
Kling, 1947
Faahraeus et al . , 1950
Faahraeus et al . , 1950
Huss et al. , 1952
Bancroft et al . , 1957
Little, 1954
Country
Sweden
Sweden
Sweden
Sweden
Sweden
Sweden
U.S.A.
Canada
Place or
type of
population
Rural district
Town
Town
Stockholm
suburb
Town
Malmoe
"Huskerville"
Edmonton
No. cases
attributed
to supply
10b
63
53
9
63C
138
45
76l>
      a Unadjusted rate among persons presumably consuming contaminated supply.

      b Estimated from author's data.

      c Includes  cases attributed to other modes of transmission.

-------
     TABLE 112 .   (continued)
00
-U
No.
1
2
3
4
5
6
7
8
Attack
rate per
100a
--
0.5
0.2
--
0.2
0.1
6.7
<0.1b
Character
of Episode
Sporadic cases
Epidemic
Epidemic
Sporadic cases
Epidemic
Epidemic
Epidemic
Epidemic
Duration of
waterborne
phase
Yrs
5 mo
3 mo
3 mo
7 mo
6 mo
5 weeks
2 weeks
Type of supply
held responsible
Private well , pond
Municipal system
Filtered surface water
Municipal system
Untreated deep well water
Municipal system
Proximate contamination
Municipal system
Untreated deep well water
Municipal system
Filtered surface water
Municipal system
Proximate contamination
Municipal system
Chlorinated surface water
     a Unadjusted rate among persons presumably consuming contaminated supply.

     b Estimated from author's data.

     c Includes  cases attributed to other modes of transmission.

-------
Infective Dose  of Viruses —
     Virologists  feel  that  one  plaque-forming  unit  (pfu)  -  one
viral  particle  that grows  in  the  laboratory  media -  constitutes
an infectious viral dose.   However,  there  is a difference
between infection and  disease (637);  the  diseased person  mani-
fests  a variety of symptoms  and readily  recognizes  that  he  is
sick;  an infected person  has  the  material  in his  system,  but
does not necessarily show symptoms  of the  disease.   It has  been
estimated that of every 100  to  1,000  people  who are  infected,
only one will manifest the  clinical  symptoms of disease.   How-
ever,  it is not quite  as  simple as  these  statistics  suggest,  for
an infected individual can  serve  as  a carrier  or  source  within
the community and transmit  this disease  to other  people  (637).

     Table 113 shows the  minimal  infective doses  of attenuated
polio virus for human  hosts  by  oral  routes.  The  infected rate
with 20 or more pfu was 100 percent;  with 2  pfu,  67  percent of
the individuals was infected.


       TABLE 113.  MINIMAL INFECTIVE DOSES  OF ATTENUATED
       POLIO VIRUSES  FOR HUMAN HOSTS BY ORAL  ROUTES(637).

Subject
Adults



Premature
Infants


Poll
(SM


Poli
(Fox

Virus
o virus Type I
Strain)


o virus Type III
Strain)

Dose
(Pfu)
200
20
2
0.2
10
2.5
1
Carrier*
Rate
4/4
4/4
2/3
0/2
2/3
3/9
3/10
Infected
Percent
100
100
67
0
67
33
30

* Number of persons developed  into  carrier  for  the
  virus/number  of  persons  who  had  taken  the virus  orally.


      It has been mentioned that infection with small amounts of
virus  in water  would probably  immunize individuals rather than
produce disease.   This may be  substantiated by the fact that
sewage workers  continually exposed  to small amounts of infected
material had  the lowest rate of absenteeism among  all the occu-
pation groups studied (52).

      An adequate biological indicator for viruses  in various
waters is  not currently available;  however, efforts are being
made  to find  better indicators.  For example, ratios of coli-
phages to  human enteric viruses and the  coliform-virus ratio
                               285

-------
have been investigated ('235,  364)     Also, a high degree of
coliforms and coliphage occurring in water samples (346)'  as
well as a yeast and two acid-fast bacilli recovered from waste-
water, resist chlorination at a level sufficient to inactivate
viruses.  This suggests that they may be useful indicators of
wastewater chlorination efficiency (201).
                              286

-------
                           REFERENCES

 1.   Adams, A.  P.  and J.  C.  Spendlove.   Coliform Aerosols
     Emitted by Sewage Treatment Plants.   Science.  169(3951)-
     1218-1220.  September 18, 1970.                 	

 2.   Adams, B.  J.  and R.  S.  Grimmell.  Performance of Regionally
     Related Wastewater Treatment Plants.   JWPCF.  45(10):2088-
     2163.   October 1973.                           —

 3.   Adams, C.  E.   Removing  Nitrogen  from Waste Water.  Environ-
     mental Science and Technology.   7_(8) :696-701 .  August 1973.

 4.   Adams, C.  E. ,  P. A.  Krenkel, and E.  C.  Bingham.  Investiga-
     tion into  the  Reduction of High  Nitrogen Concentrations.
     Advances in Water Pollution Research.   1970(1):13/1-13.

 5.   Adams, V.  D. ,  E. J.  Middlebrooks,  and  P. D. Nance.  Organic
     Residue in a  Recycled Effluent.   Part  I.  Water and Sewage
     Works.  l_2_i(6): 82-84.  September 1975.

 6.   Advances in Wastewater  Treatment.   Advanced Wastewater
     Treatment  Research Facility.  Pomona,  Ca.

 7.   Agnew, R.  W. ,  e_t aj_.   A Biological Adsorption System for
     the Treatment  of Combined Sewer  Overflow.  Presented at  the
     46th Water Pollution  Control Federation Annual Conference,
     Cleveland, Ohio.  October 2, 1973.

 8.   Akin,  E. W.,  W.  H. Benton, and W.  F.  Hill, Jr.  Enteric
     Viruses in Ground and Surface Waters:   A Review of Their
     Occurrence and Survival.   Proceedings  Thirteenth Water
     Quality Conference;  Virus and Water Quality; Occurrence  and
     Control.  University  of Illinois,   pp.  59-74.  February  1971

 9.   Al-Layla,  M.  A.  and  E.  J. Middlebrooks.  Optimum Values  for
     Operational Variables in Turbidity Removal.  Water and
     Sewage Works.   1_2J_(8): 66-69.  August 1974.

10.   Albertson, 0.  E. and  R. J. Sherwood.   Phosphate Extraction
     Process.  JWPCF.  41(8):1467-1490.  August 1969.

11.   Albone, E. S. , e_t a_l_.  Fate of DDT in  Severn Estuary
     Sediments.  Environmental Science and  Technology.  6(10)-
     914-919.  October 1972.                            ~

12.   Alsentzer, H.  A.  Ion Exchange in Water Treatment.  JAWWA
     £5.( 6): 742-748.  June  1963.

13.   Ames,  L. L.,  Jr., and R.  B. Dean.   Phosphorus Removal  from
     Effluents  in  Alumina  Columns.  JWPCF.   42(5)-R161-R172
     May 1970.                               —


                               287

-------
 14.   Amirhor,  P.  and  R.  S.  Engelbrecht.   Virus  Removal  by  Poly-
      el ectrolyte-Aided  Filtration.   JAWWA.   67.(4) :187-192.
      April  1975.

 15.   Amramy, A.   Waste  Treatment  for Ground  Water  Recharge.
      Advances  in  Water  Pollution  Research.   1964(2):147-168.

 16.   Andelman,  J.  B.  The  Effect  of  Water Treatment  and Distri-
      bution on  Trace  Element  Concentrations.   In:   Chemistry  of
      Water  Supply  Treatment and Distribution.   A.  J.  Rubin, ed.
      Ann Arbor  Science  Publishers, Ann Arbor, Michigan,   pp.  423-
      440.   1975.

 17.   Andelman,  J.  B.  and M. J. Suess.  Polynuclear Aromatic
      Hydrocarbons  in  the Water Environment.   Bulletin  of the
      World  Health  Organization.   431:479-508.  1970.

 18.   Argo,  D. G. and  G.  L. Culp.  Heavy  Metals  Removal  in  Waste-
      water  Treatment  Processes.   Part 1.   Water and  Sewage Works.
      l_l_9(8):62-65.  August 1972.

 19.   Argo,  D. G. and  G.  L. Culp.  Heavy  Metals  Removal  in  Waste-
      water  Treatment  Processes.   Part 2.   Pilot Plant  Operation.
      Water  and  Sewage Works.  1_1_9(9): 128-133.   September 1972.

 20.   Arpa,  S. S.   Nitrogen Removal Obtained  through  Heterotrophic
      Growth in  Trickling Filters.  NTIS/PB-239-925.   August 1974.

 21.   Atkins, P. D., Jr., ll il-   Ammonia  Removal by  Physical-
      Chemical Treatment.  JWPCF.  £5(11):2372-2388.   November
      1973.

 22.  Aulenback, D. B., et. aJL  Water  Renovation Using  Deep
      Natural Sand  Beds.  JAWWA.   £7(9):510-515.  September 1975.

 23.  Axelson, 0.,  ejt  al..  Herbicide  Exposure  -  Mortality and
     Tumor Incidence; An Epidemiological  Survey of Swedish
     Railway Workers.  Pesticide  Abstracts.   75-1886.   1975.

24.  Balakrishnan, S. and W. W. Eckenfelder.  Nitrogen  Removal
     by Modified Activated Sludge Process.   Journal  of  the
     Environmental Engineering Division,  ASCE.   96(SA3):501-512.
     April  1970.

25.  Balakrishnan, S., W. W. Eckenfelder,  and C. Brown.  Organics
     Removed by a  Selected Trickling  Filter  Media.   Water and
     Wastes Engineering.  6^(1 ): A22-A25.    January 1969.

26.  Bargman, R. B., J.  M.  Betz,  and W.   F. Garber.   Nitrogen-
     Phosphate Relationships and  Removals Obtained by  Treatment
      Processes at  the Hyperion Treatment  Plant.  Advances  in
     Water Pollution  Research.  1970(1):14/1-17.

                              288

-------
27.   Barnard,  J.  L.   Cut P and N Without Chemicals.  Water and
     Wastes Engineering.  JJ[:33-36.   July 1974.

28.   Barnes,  G.  E.   Disposal  and Recovery of Electroplating
     Wastes.   JWPCF.   4£(8):1459-1470.  August 1968.

29.   Baroni,  C.,  G.  J.  Van Esch, and V. Saffiotti.  Carcino-
     genesis  Tests  of Two Inorganic Arsenicals.  Archives of
     Environmental  Health.  _7_:668-674.  1963.

30.   Barrow,  N.  J.   Effect of Previous Additions of Phosphate
     on Phosphate Adsorption by Soils.  Soil Science.  118:82-89.
     August 1974.

31.   Barth, E. F.,  ejt al_.  Field Survey of  Four Municipal Waste-
     water Treatment Plants Receiving  Metallic Wastes.   JWPCF.
     3_7(8):1101-1117.  August 1965.

32.   Barth, E. F. ,  et_ «*!_.  Phosphorus  Removal  from Wastewater
     by Direct Dosing of Aluminate to  a Trickling  Filter.   JWPCF.
     41_(11):1932-1942.   November 1969.

33.   Barth, E. F. ,  e_t al.  Summary Report on the  Effects of
     Heavy Metals on tFe Biological Treatment  Processes.   JWPCF.
     3_7.(l):86-96.  January 1965.

34.   Barton,   R..  R. , et al.  UV-Ozone  Water-Oxidation/Steri1iza-
     tion Process.   FTII7AD/A-004 205/1WP.   September  1974.

35.   Barua, D.   Survival of Cholera Vibrios in Food, Water,  and
     Fomites.  Principals and Practice of Cholera  Control.
     Chapter  4:29-31.   1970.

36.   Bauer, R. C. and V.  L. Snoeyink.   Reactions  of Chloramines
     with Active Carbon.   JWPCF.  45(11):2290-2301.  November
     1973.

37.   Baughman, G. L., et  al.  Chemistry of  Organo-Mercurials in
     Aquatic  Systems. ~TP7T"660/3-73-012.  September 1973.

38.   Bausum,  H.  T.  ,  e_t  a_l_.  Bacterial  Aerosols Resulting from
     Spray Irrigation with Wastewater.  U.S.  Army Medical
     Research and Development Laboratory, Fort Detrick,  Md.
     June  1976.

39.  Bean, E. L.  Potable  Water -  Quality Goals.   JAWWA.  66(4):
     221-230.  April 1974.                                 ~~

40.  Beckman, W. J. , e_t al.   Combined Carbon Oxidation-Nitrifi-
     cation.  JWPCF.  44TTO):1916-1930.   October 1972.
                                289

-------
41.  Bellar, T. A., J. J. Lichtenberg and R. C.  Kroner.  The
     Occurrence of Organohalides  in Chlorinated  Drinking Waters.
     NTIS/PB-238 589.  November 1974.

42.  Bellar, T. A., J. J. Lichtenberg, and R. C.  Kroner.  The
     Occurrence of Organohalides  in Chlorinated  Drinking Waters.
     JAWWA.  1_6^:703-706.  December 1974.

43.  Bellin, J. S. and I. Chow.   Biochemical Effects of Chronic
     Low-Level Exposure to Pesticides.  Research  Communications
     in Clinical Pathology and Pharmacology.  9_(2) :325-337.
     October 1974.

44.  Benarde, M. A.  Land Disposal and Sewage Effluent:  Appraisal
     of Health Effects of Pathogenic Organisms.   JAWWA.  65(6):
     432-440.  June 1973.

45.  Bendixen, T. W. , ejt aj_.  Cannery Waste Treatment  by Spray
     Irrigation-Runoff.  JWPCF.   4J_(3): 385-391 .   March 1969.

46.  Bennett, P. J.,  S. Narayarian, and E. Hindin.  Removal of
     Organic Refractories by Reverse Osmosis.  Proceedings,
     23rd Purdue Industrial  Waste Conference, May  1968.  pp.
     1000-1017.

47.  Berg, E. L., C.  A. Brunner,  and R. T. Williams.   Single
     Stage Lime Clarification of  Secondary Effluent.   Water and
     Wastes Engineering.   7.(3):42-46.  March 1970.

48.  Berg, G.  Integrated Approach to Problem of  Viruses in
     Water.  Journal  of the Sanitary Engineering  Division, ASCE.
     i7_(SA6):867-882.   December 1  971 .

49.  Berg, G.  Removal of Viruses from Sewage, Effluents, and
     Waters.   1:  A Review.   World Health Organization Bulletin.
     1£:451-460.  May 1973.

50.  Berg, G. Removal  of Viruses  from Sewage, Effluents and
     Waters.   2:  Present and Future Trends.  World Health
     Organization Bulletin.   4_9:461-469.  May 1973.

51.  Berg, G.  Removal of Viruses from Water and  Wastewater.
     Proceedings Thirteenth Water Quality Conference;  Virus
     and Water Quality:  Occurrence and Control.   University of
     Illinois.   pp. 126-136.  February 1971.

52.  Berg, G.  Transmission of Viruses by the Water Route.
     Interscience Publishers, New York.  December  1965.

53.  Berg, G.  Virus  Transmission by the Water Vehicle.  I:
     Viruses.  Health Laboratory  Science.  3.(2):86-88.  April
     1966.

                               290

-------
54.  Berg,  G.   Virus Transmission by the Water Vehicle.   II:
     Virus  Removal  by Sewage Treatment Procedures.  Health
     Laboratory Science.   3_(2) :90-100.  April  1966.

55.  Berg,  G.   Virus Transmission by the Water Vehicle.   Ill:
     Removal  of Viruses by Water Treatment Procedures.  Health
     Laboratory Science.   3_(3) :170-181 .   July 1966.

56.  Berq,  G., R.B. Dean, and D.R. Dahling.  Removal of Polio-
     virus  1  from Secondary Effluents by Lime Flocculation and
     Rapid  Sand Filtration.  JAWWA.  60(2): 193-198.  February
     1968.

57.  Berg,  J.W. and F. Burbank.  Correlations Between Carcino-
     genic  Trace Metals in Water Supplies and Cancer Mortality.
     Annals of the New York Academy of Sciences.  199:249-261.
     June 28, 1972.

58.  Bernardin, F.E.  Cyanide Detoxification Using Adsorption
     and Catalytic Oxidation on Granular Activated Carbon.
     JWPCF.  45J2)-.221-231 .  February 1973.

59.  Bernhardt, H., ejt a]_.  Phosphate and Turbidity Control by
     Flocculation  and Filtration.  JAWWA.  63(6):355-368.
     June 1971 .

60.  Bertucci, J.,  D. Zenz, and C. Lue-Hing.  Report  on the
     Virological Studies of Big Creek and Evelyn  Reservoir in
     Fulton County, Illinois, February,  1973.   Metropolitan
     Sanitary District of  Greater  Chicago.  September 6,  1973.

61.  Besik, F.K.   Renovating Domestic Sewage  to  Drinking  Water
     Quality.  Water  and Pollution Control.  Hl(4):58-63, 97.
     April  1973.

62.  Besik, F.K.   Waste Water Reclamation  in  a  Closed System.
     Water and  Sewage Works.  118(7):213-219.   July 1971.

63.  Betz  Laboratories.   Betz  Handbook  of Industrial  Water
     Conditioning.  1962.

64.  Bishop,  D.  F., e_t aJL  Physical-Chemical  Treatment  of
     Municipal  Wastewater.  JWPCF.  4^(3) :361-371.   March 1972.

65.  Bishop,  D.  F. , ejt ^1_.  Physical-Chemical  Treatment  of Raw
     Municipal  Wastewater.  EPA-670/2-73-070.   September 1973.

66.  Bishop,  D.  F., J.  A.  Heidman, and  J. B.  Stamberg.   Single-
     stage Nitrification-Denitrification.  EPA-670/2-75-051.
     June  1975.
                                291

-------
 67.   Bishop, D.  F.,  J.  A.  Heidman, and J.  B.  Stamberg.   Single-
      stage Nitrification-Denitrification.   JWPCF.  48(3)•520-532
      March 1976.                                    —

 68.   Bishop, D.  F. ,  ejt  al .   Studies on Activated Carbon Treat-
      ment.  JWPCF.   39^(27:188-203.  February  1967.

 69.   Black,  A.  P.,  A.  T.  DuBose,  and R.  P.  Vogh.  Physical-
      Chemical  Treatment of  Municipal Wastes  by Recycled Magne-
      sium  Carbonate.   EPA/660/2-74-055.   June 1974.

 70.   Blanck,  C. A.  and  D. J.  Sulick.   Activated Carbon  Fights
      Bad Taste.   Water  and  Wastes  Engineering.   12(9):71-74.
      September  1975.

 71.   Boardman,  G. and 0. J.  Sproul.   Protection of  Viruses
      during  Disinfection by  Adsorption to  Particulate  Matter.
      Presented  at the 48th  Annual  Conference,  Water  Pollution
      Control  Federation, Miami, Florida.   October 1975.

 72.   Bouwer,  H.  Use of the  Earth's  Crust  for  Treatment or
      Storage  of Sewage  Effluent and  Other  Waste Fluids.  CRC
      Critical Reviews in Environmental Control,   pp. 111-130
      March 1976.

 73.   Bouwer, H., J.  C. Lance, and  M.  S.  Riggs.   High-Rate Land
      Treatment II:  Water Quality  and  Economic  Aspects  of the
      Flushing Meadows Project.  JWPCF.  £6(5):844-859.   May 1974.

 74.   Boyden, C. R.  Trace Element  Content and  Body Size  in
      Mollusks.  Nature.   5_1:311-314.   September  1974.

 75.   Braswell, J.  R.  and A.  W. Hoadley.  Recovery of Escherichia
             m Chlorinated Secondary Sewage.   Applied Micro-
               28^328-329.   August 1974.

 76.  Brewer,  R.  F.   Fluorine.  In:   Diagnostic  Criteria  for
     Plants and Soils.   H.  D. Chapman, ed.  Quality Printing
     Company, Abilene,  Texas,  pp. 180-196.  1973.

 77.  Brinska, G.  A.   Sludge  Disposal by Incineration at Alcosan
     Proceedings of  the  National  Conference on Municipal Sludge'
     Management,   pp.  157-161.  June 11-13, 1974.

78.  Brown, J.  R.  and  L.  Y.  Chow.   Comparative Study of DDT and
     Its  Derivatives  in  Human Blood Samples in Norfolk County
     and  Holland Marsh,  Ontario.   Bulletin of  Environmental
     Contamination and  Toxicology.   1_3_(4): 483-488.

79.  Brown, R.  E.  Significance  of Trace Metals and Nitrates in
     Sludge Soils.   JWPCF.   £7_( 1 2): 2863-2875.   December 1975.
                               292

-------
80.   Brown, T. S., ejt a]_.  Virus Removal by Diatomaceous Earth
     Filtration - Part 1.  JAWWA.  6j6(2): 98-1 02.

81.   Brown, T. S., J. F.  Malina, Jr., and B. D. Moore.  Virus
     Removal by Diatomaceous Earth Filtration  - Part 2.  JA-WWA.
     61:735-738.   December 1974.

82.   Brown, T. S., e_t a_l_.  Virus Removal by Diatomaceous Earth
     Filtration.   In:  Virus Survival in Water and Wastewater
     Systems.  Malina and Sagik, eds.  Water Resources Symposium
     #7.  pp. 129-144.  1974.

83.   Browning, G. E. and J. 0. Mankin.  Gastroenteritis Epidemic
     Owing to Sewage Contamination of Public Water Supply.
     JAWWA.  81_(11): 1465-1470.  November 1966.

84.   Browning, J. E.  New Water Cleanup Roles  for Powered
     Activated Carbon.  Chemical Engineering.  79:36-48.
     February 21, 1972.

85.   Brungs, W. A.  Effects of Residual Chlorine on Aquatic  Life
     JWPCF.  45(10):2180-2193.  October 1973.

86.   Brunner, D.  R. and 0. J. Sproul.  Virus Inactivation  during
     Phosphate Precipitation.  Journal of the  Sanitary Engineer-
     ing Division, ASCE.   £6(SA2):365-379.  April 1970.

87.   Bryan, E. H.  Concentrations of  Lead in Urban Storm Water.
     JWPCF.  4j[(10):2419-2421 .

88.   Bryan, F. L.  Diseases Transmitted by  Foods Contaminated
     by Wastewater.  In:   Wastewater  Use in the Production of
     Food and Fiber - Proceedings.  EPA-660/2-74-041.  pp.  16-
     45.  June 1974.

89.   Buelow, R. W. and G. Walton.  Bacteriological Quality vs.
     Residual Chlorine.  JAWWA.  6_3_(1 ): 28-35.   January 1971.

90.   Buelow, R. W. , et_ al .  Nitrate Removal by Anion-Exchange
     Resins.  JAWWA.  67T"9): 528-534.  September 1975.

91.   Buescher, C. A., J. H. Dougherty,  and  R.  T. Skrinde.
     Chemical Oxidation  of  Selected Organic Pesticides.  JWPCF.
     3_6(8):1005-1014.  August  1964.

92.   Burns, D. E. and G. L. Shell.  Carbon  Treatment  of a
     Municipal Wastewater.  JWPCF.  46(1 ):148-164.   January
     1974.                          —

93.   Burns, D. E., E. R. Baumann, and C. S. Oulman.   Particulate
     Removal on Coated Filter  Media.  JAWWA.   62(2):121-126.
     February 1970.


                               293

-------
 94.  Cabelli, V. J. and W. P. Heffernan.  Elimination of
      Bacteria by the Soft Shell Clam, Mya arenaria.  Journal
      of the Fisheries Research Board of Canada.77:1579-1586.
      1970.

 95.  Cabelli, V. J., e_t aj_.  The Impact of Pollution on Marine
      Bathing Beaches:  An Epidemiological Study (Personal
      Communication).  1975.

 96.  Caldwell, G. G., ejt aj_.  Epidemic of Adenovirus Type 7
      Acute Conjunctivitis in Swimmers.  American Journal of
      Epidemiology.  ££(3):230-234.  March 1974.

 97.  California Morbidity.  Weekly Report from the  Infectious
      Disease Section, California State Dept. of Health.  June
      11, 1976.

 98.  California Morbidity.  Weekly Report from the  Infectious
      Disease Section, California State Dept. of Health.
      October 8, 1976.

 99.  Calmon, C.  Notes and Comments Relative to an  Article,
      Arsenic Removal from Potable Water, by Ervin Bellack
      which appeared in the July 1971 Journal.  JAWWA.  65(8):
      568-569.  August 1973.

100.  Calmon, C.  Trace Heavy Metal Removal by Ion Exchange.
      Personal Communication.

101.  Calmon, C. and H.  Gold.   Treatment of Industrial Waste  by
      Ion Exchange.  In:   Proceedings of the Second  National
      Conference on Complete Water Reuse.  American  Institute
      of Chemical Engineers, New York, 1975.  pp. 820-842

102.  Carlson, R. M., e± a]_.  Facile Incorporation of Chlorine
      into Aromatic Systems during Aqueous Chlorination Process,
      Environmental Science and Technology.  £:674-675.  August
      1975.

103.  Carnes, B. A., J.  M.  Eller, and J. C. Martin.  Integrated
      Re-Use-Recycle Treatment Processes Applicable  to Refinery
      and Petrochemical  Wastewaters.  American Society of
      Mechanical Engineers, New York.  1971.

104.  Carney, J. F., C.  E.  Carty, and R. R. Colwell.  Seasonal
      Occurrence and Distribution of Microbial Indicators and
      Pathogens in the Rhode River of Chesapeake Bay.  Applied
      Microbiology.  3£(5):771-780.  November 1975.

105.  Carpenter, R. L. ,  e_t a_l_.  The Evaluation of Microbial
      Pathogens in Sewage and Sewage-Grown Fish.  In:  Waste-
      water Use in the Production of Food and Fiber  - Proceed-
      ings.   EPA-660/2-74-041.  pp. 46-55.  June 1974.
                               294

-------
106.   Case,  0.  P.   Metallic  Recovery from Waste Waters  Utilizing
      Cementation.   EPA-670/2-74-008.   January 1974.

107.   Cassel,  A.  F.  and R.  T.  Mohr.   Sludge Handling  and Disposal
      at Blue  Plains.   Proceedings of the National  Conference
      on Municipal  Sludge Management,   pp.  171-176.   June 11-13,
      1974.

108.   Chahal ,  K.  S.   Microbial  Activities during Sewage Treatment
      in Lagoons.   I.   Changes  in Aerobic and Anaerobic Bacteria,
      Actinomycetes,  and Fungi.   II.  Changes in Different Types
      of Fungi.   III.   Changes  in BOD and Dehydrogenase Activity.
      NTIS/PB-237 501/2WP.   1974.

109.   Chambers,  D.  W.   Chlorination for Control of Bacteria and
      Viruses  in Treatment Plant Effluents.  JWPCF.   43(2) :228-
      241.  February 1971.

110.   Chang, P.  W.   Effect of Ozonation on Human Enteric Viruses
      in Water from Rhode Island Rivers.  NTIS/PB-236 421/4WP.
      July  1974.

111.  Chang, S. L.   Modern Concept  of  Disinfection.  Journal
      of  the Sanitary  Engineering Division,  ASCE.  97(SA5)-
      689-707.  October  1971.                      —

112.  Chang, S. L., et. aj_.  Removal of  Coxsackie and Bacterial
      Viruses in Water by Flocculation.   I.   Removal of Cox-
      sackie and Bacterial Viruses  in  Water  of  Known Chemical
      Content by Flocculation with  Aluminum  Sulfate  or  Ferric
      Chloride Under Various Testing Conditions.  American
      Journal of Public  Health.   4^:51-61.   January  1958.

113.  Chang, S. L., P. C. G. Isaacs, and  N.  Baine.   Studies  on
      Destruction of Bacterial  Virus.   III.   Dynamics  of the
      Removal of Bacterial Virus  (Bacteriophage against Micro-
      coccus pyogenes  var. Albus)  in Water by  Flocculation with
      Aluminum Sulfate.  American  Journal  of Hygiene    57(3)-
      253-266.  May 1953.                            '   —

114.  Chapman, B.  Sponsors of  Science Inc.  on  Safety  of
      2,4,5-T and  Dioxin.  Clinical  Toxicology.  7(4):413-421
      1974.

115.  Chapman, S.  W.,  Jr., R. M.  Sweazy,  and D.  M. Wells.
      Nitrogen Mass Balance Determination  for  Simulated Waste-
      water Land Spreading Operations.   NTIS/PB-239-406,
      December 1974.

116.  Chaudhuri, M. and  R. S. Engelbrecht.   Removal  of Viruses
      from  Water by Chemical Coagulation and Flocculation.
      JAWWA.  6^(9):563-567.  September 1970.

                                295

-------
117.  Chaudhrui, M. and R. S. Engelbrecht.  Virus Removal in
      Wastewater Renovation by Chemical Coagulation and
      Flocculation.  Advances in Water Pollution Research.
      1970(l):II/201-22.

118.  Chen, C. L.  Virus Removal (Personal Communication).
      September 1975.

119.  Chen, C. L. and R. P. Miele.  Wastewater Demineralization
      by Continuous Counter-Current Ion Exchange Process.
      Contract No.  14-12-150.  National Environmental Research
      Center, Cincinnati, Ohio.  1972.

120.  Chen, C. L. and R. P. Miele.  Wastewater Demineralization
      by Tubular Reverse Osmosis Process.  Contract No. 14-12-150,
      National Environmental Research Center, EPA.  Cincinnati,
      Ohio.

121.  Chen, C. L. and R. P. Miele.  Wastewater Demineralization
      by Two-Stage Fixed-Bed Ion Exchange Process.  Advanced
      Treatment Research Center, EPA.

122.  Chen, C. W. and G. T. Orlob.  The Accumulation and  Signi-
      ficance of Sludge Near San Diego Outfall.  JWPCF.   44(7):
      1362-1371.  July 1972.

123.  Chen, K. and  T. Hendricks.  Trace Metals on Suspended
      Particulates.  Southern California Coastal Water Research
      Project Annual  Report.  El Segundo, Ca.  pp. 147-152.
      June 30, 1974.

124.  Chen, K. Y. and R. A. Lockwood.  Evaluation Strategies of
      Metal Pollution in Oceans.  Journal of the Environmental
      Engineering Division, ASCE.  102(EE 2):347-359.  April
      1976.

125.  Chen, M. H. ,  e_t al.  Heavy Metals Uptake by Activated
      Sludge.   JWPCF. ~T7(2):362-376.  February 1975.

126.  Chian,  E.  S.  K., W. N. Bruce, and H. H. P. Fang.  Removal
      of Pesticides by Reverse Osmosis.  Environmental Science
      and Technology.  9_(l):52-59.  January 1975.

127.  Christensen,  G. L.  Use of Ozone and Oxygen in Advanced
      Wastewater Treatment.  JWPCF.  46^(8): 2054-2055.  August
      1974.

128.  Ciaccio, L.  Water and Water Pollution Handbook.  Vol. 4.
      Marcel  Dekker,  New York,  1971.

129.  Clarke,  N.  A.,  e_t aj_.  Virus Study for Drinking Water
      Supplies.   JAWWA.   68(4):192-197.  April 1976.

                               296

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130.   Cleasby,  J.  L.   Iron and Manganese Removal  - a Case Study.
      JAWWA.   67_(3):147-149.   March 1975.

131.   Cleasby,  J.  L. ,  e_t aj_.   Trickling Filtration of a Waste
      Containing NTA.   JWPCF.   46^(8): 1872-1887.   August 1974.

132.   Cliver,  D. 0.  and J. F.  Herrmann.  Proteolytic and
      Microbial  Inactivation  of Enteroviruses.   Water Research.
      6.(7):797-805.  ' July 1972.

133.   Cliver,  D. 0.,  K. M. Green, and  J. Bouma.   Viruses and
      Septic  Tank Effluent.  Small  Scale Waste Management
      Project,  University of  Wisconsin, Madison,  Wisconsin.
      1975.

134.   Colston,  N.  V.,  Jr.  Characterization and Treatment of
      Urban Land Runoff.  EPA-670/2-714-096.  December 1974.

135.   Comer,  S.  W. ,  et^ ajk  Exposure of Workers to  Carbaryl.
      Bulletin of Environmental Contamination and Toxicology.
      1_3(4):385-391.  1975.

136.   Committee on Public Health Activities.  Coliform Organisms
      as an Index of Water Safety.   Journal of the  Sanitary
      Engineering Division, ASCE.  87JSA6):41-58.   November  1961.

137.   Conley, W. R.   High-Rate Filtration.  JAWWA.   64_(3):203-
      206.  March 1972.

138.   Cookson, J. T.  The  Chemistry of  Virus Concentration  by
      Chemical  Methods.   Developments  in  Industrial  Microbiology.
      15:160-173.  1973.

139.   Cookson, J, T.  Removal  of Submicron  Particles in  Packed
      Beds.  Environmental Science and  Technology.  £:128-134.
      February 1970.

140.   Cooper, B. S.  and  R. C.  Harris.    Heavy Metals  in Organic
      Phases of River and  Estuarine Sediment.  Marine  Pollution
      Bulletin.  5J2):24-26.    February  1974.

141.   Cooper, R. C.   Health Considerations  in Use of Tertiary
      Effluents.  Journal  of  the Environmental Engineering
      Division, ASCE.   1P_3_(EE1) :37-47.  February  1977.

142.  Cooper, R.  C.  Wastewater  Contaminants and  their Effects
      on  Public Health.   California State Water  Resources
      Control Board.   1975.

143.  Cortinovis, D.   Activated  Biofilter:   A  Modesto  Invention
      Gains Acceptance  Throughout  North America.   The  Bulletin
      (California Water Pollution  Control Association).   12(2):
      38-41.  October  1975.
                                297

-------
144.  Craun, G. F.  Microbiology - Waterborne Outbreaks.  JWPCF.
      4_7(6) :1566-1581 .  June 1975.

145.  Craun, G. F. and L. J. McCabe.  Review of the Causes of
      Waterborne-Disease Outbreaks.  JAWWA.  65(1):74-84.
      January  1973.

146.  Crump-Weisner,  H. J., H. R. Feltz, and M. L. Yates.  A
      Study of the Distribution of Polychlorinated Biphenyls
      in the Aquatic  Environment.  U.S. Geological Survey
      Journal  of Research.  1:603-607.  September  1973.

147.  Cruver,  J.  E. and I, Nusbaum.  Application of Reverse
      Osmosis  to Wastewater Treatment.  JWPCF.  £6(2):301-311.
      February 1974.

148.  Cruver,  J.  E.   Reverse Osmosis - Where it Stands Today.
      Water and Sewage Works.  1_20_(10): 74-78.  October 1973.

149.  Cruver,  J.  E. and I. Nusbaum.  Application of Reverse
      Osmosis  to Wastewater Treatment.  JWPCF.  46(2):301-311.
      February 1974.

150.  Culbertson,  C.  G.  The Pathogenicity of Soil Amebas.
      Annual Review of Microbiology.  2I_5:231.  1971.

151.  Gulp, G.  L.  and A.  J.  Shuckrow.  Physical-Chemical Tech-
      niques for Treatment of Raw Wastewaters.  Public Works.
      103_(7):56-60.  July 1972.

152.  Culp, R.  L.   Breakpoint Chlorination for Virus  Inactiva-
      tion.  JAWWA.  6^:699-703.   December 1974.

153.  Culp, R.  L.   Breakpoint Chlorination for Virus  Inactivation
      In:   Virus  Survival  in Water and Wastewater  Systems.
      Malina and  Sagik, eds.  Water Resources Symposium #7.
      pp.  158-165.   1974.

154.  Culp, R.  L.   Virus  and Bacteria Removal in Advanced
      Wastewater Treatment.   Public Works.  l_0_2:84-88.  June
      1971.

155.  Culp, R.  L.   Wastewater Reclamation at South Tahoe Public
      Utilities District.   JAWWA.  60(l):84-94.  January 1968.

156.  Daniels,  S.  L. and  D.  G. Parker.  Removing Phosphorus
      from Waste  Water.  Environmental Science and Technology.
      ^(8):690-694.  August 1973.

157.  David Volkert and Associates.  Monograph on  the Effective-
      ness and Cost of Water Treatment Processes for  the
      Removal of Specific Contaminants.   Contract  #68-01-1833.
      EPA, Office of  Air and Water, August 1974.
                               298

-------
158.   Davis,  E.  M.  and S.  R.  Keen.   Municipal  Wastewater
      Bacteria Capable of  Surviving Chlorination.   Health
      Laboratory Science.   1_1_: 268-274.  October 1974.

159.   Davis,  J.  A.   Ill and J.  Jacknow.   Heavy Metals in Waste-
      water in Three Urban Areas.  JWPCF.  47^(9): 2292-2297.
      September 1975.

160.   Davis,  W.  K.   Land Disposal III:  Land Use Planning.
      JWPCF.   45_(7): 1485-1488.   July 1973.

161.   DeBoise, J.  N. and J. F.  Thomas.  Chemical Treatment for
      Phosphate Control.  JWPCF.  47(9) :2246-2255.   September
      1975.

162.   Degradation of Synthetic Organic Molecules in  the  Biosphere:
      Natural, Pesticidal, and Various Other Man-Made Compounds.
      National Academy of Sciences, Washington, D.C.  1972.

163.   DeMichele, E.  Pathogenic Organisms in the Murderkill
      River Estuary.  JWPCF.  4J[(4) :772-776.  April  1974.

164.   DeMichele, E.  Water Reuse, Virus  Removal and  Public
      Health.  In:  Virus Survival  in Water and Wastewater
      Systems.  Malina and Sagik, eds.   Water Resources
      Symposium #7.  pp.  45-56.  1974.

165.   Dennis, J. M.  1955-1956  Infectious Hepatitis  Epidemic  in
      Delhi,  India.  JAWWA.  51_: 1 288-1296.  October  1959.

166.   de Vries, J.  Soil  Filtration of Wastewater  Effluent and
      the  Mechanism of  Pore Clogging.  JWPCF.   4_4(4): 565-573.
      April 1972.

167.   DeWalle,  F.  B. and  E. S.  K.  Chian.  Removal  of Organic
      Matter  by Activated Carbon Columns.   Journal  of the
      Environmental Engineering  Division, ASCE.   1_00(EE5): 1 089-
      1104.   October  1974.

168.  Diaper, E. W. J.  Disinfection  of  Water  and  Wastewater
      Using Ozone.  In:   Johnson,  J.  D.   Disinfection -  Water
      and  Wastewater.   Ann  Arbor Science Publishers, Ann Arbor,
      MI.  1975.   pp.  211-231.

169.  Diaper, E. W. J.  Microstraining  and  Ozonation of Water
      and  Wastewater.   Water  and Wastes  Engineering.  5_(2):56-
      58.  February 1968.

170.  Diaper,  E. W. J.  Practical  Aspects of  Water and Waste
      Water  Treatment  by  Ozone.   In:   Ozone in Water and Waste-
      water  Treatment.  Ann  Arbor  Science Publishers, Ann Arbor,
      MI.  pp.  145-179.   1972.

                                299

-------
 171.  Diaper, E. W. J. and G. E. Glover.  Microstraining of
       Combined Sewer Overflows.  JWPCF.  43(10):2101-2113
       October 1971.

 172,  Directo, L.  S. and C» Chen,  Pilot Plant Study of Physical-
       Chemical Treatment.  47th Annual Water Pollution Control
       Federation Conference.   Denver, Colorado.  October 1974.

 173.  Directo,  L.  S., R. P.  Miele, and A.  N.  Masse.  Phosphate
       Removal by Mineral  Addition to Secondary and Tertiary
       Treatment  Systems.   Presented at the  27th Purdue Industrial
       Waste Conference.   May  1972.

 174.  Directo, L.  S. ,  C.  Chen,  and  R.  P.  Miele.  Physical
       Chemical Treatment  of Raw Sewage.   Advanced  Waste Treat-
       ment  Research Laboratory,  EPA.

 175.  Director,  L.  S. ,  C.  Chen,  and R.  P. Miele.   Two-Stage
       Granular Activated  Carbon  Treatment.   Advanced Waste
       Treatment  Research  Center,  EPA.

 176.   Disinfection  of  Wastewater, Task  Force  Report.   EPA  Office
       of  Research and  Development.   July  1975.

 177.   Dismukes,  W,  E., e_t  aj_.  An Outbreak  of  Gastroenteritis
       and Infectious Hepatitis Attributed to  Raw Clams.
       American Journal of  Epidemiology.   8jK5): 555-561.   1969.

 178.   Disposal of Wastes  from Water Treatment  Plants  -  Part I
       JAWWA.   61(10):541-566.  October  1967.

 179.   Dixon,  J. K.  and M.  W. Zielyk.  Control  of the  Bacterial
       Content  of Water with Synthetic Polymeric Flocculants.
       Environmental Science and Technology.   3:551-558   June
       1969.                                   ~

 180.  Dowty, B.,  e_t a]_.  Halogenated Hydrocarbons  in  New Orleans
      Drinking Water and Blood Plasma.  Science.   187(4171):75-
      77.   January 10,  1975.

 181.  Dreisbach,  R.  H.   Handbook of Poisoning:  Diagnosis and
      Treatment.   Lange Medical  Publications, Los Altos, Ca.


182.  Dryden, F.  D.   Mineral Removal by Ion  Exchange, Reverse
      Osmosis and Electrodialysis.  Presented at the Workshop
      on  Wastewater and Reuse,  South Lake Tahoe, Ca.  June  25-
      26,  1970.

183.  puddles, G.  A., S.  F. Richardson, and  E.  F.  Barth.
      Plastic-Medium Trickling Filters for Biological Nitrogen
      Control.  JWPCF.   4j6(5): 937-947.   May  1974;

                              300

-------
184.



185.


186.



187.
188.
189.
190.
191.
192.
193.
194.
195.
196.
Dugan,  G.  L. ,  ejt aj_.   Land Disposal  of Sewage in Hawaii
a Reality?  Water & Sewage Works.   121(11):64-65.  November
1974.

Dugan,  G.  L. ,  ejt aj[.   land Disposal  of Wastewater in
Hawaii.   JWPCF.   47_(8): 2067-2087.   August 1975.

Dugan,  P.  R.   Bioflocculation and the Accumulation of
Chemicals  by Floe-Forming Organisms.  EPA-600/2-75-032.
September  1975.

Dunham,  J.,  R.  W. O'Gara, and F. B.  Taylor.  Studies on
Pollutants from Processed Water:  Collection from Three
Stations and Biologic Testing for Toxicity and Carcino-
genesis.  American Journal of Public Health.  57(12):2178-
2185.   December 1967.
Durum, W. H.
Distribution
of Science.
and J.  D.  Hem.   An Overview of Trace Element
Patterns in Water.  Annals, New York Academy
199:26-36.   June 28, 1972.
Duvel, W. A., Jr. and T. Helfgott.  Removal
Organics by Reverse Osmosis.  JWPCF.  47(1)
January 1975.
                               of Wastewater
                               57-65.
Eckenfelder, W. W., Jr.
Economics and Techniques
122_(6):62-65.  September
            Wastewater
            - Part I.
            1975.
Treatment
Water and
Design:
Sewage Works
Edwards, V. H. and P. C. Schubert.  Removal of  2,4-D  and
Other Persistent Organic Molecules from Water Supplies  by
Reverse Osmosis.  JAWWA.  6J5(1 0): 61 0-61 6.  October  1974.

Eichelberger, J. W. and J. J. Lichtenberg.  Carbon
Adsorption for Recovery of Organic Pesticides.   JAWWA.
63J1): 2.5-27.  January 1971.

El-Dib, M. A., F. M. Ramadan, and M.  Ismail.  Adsorption
of Sevin and  Baygon on Granular  Activated  Carbon.   Water
Research.  9:795-798.  1975.
Eliassen, R. and G. Tchobanoglous.   Chemical
of Wastewater for  Nutrient  Removal.   JWPCF.
R180.  May  1968.
                                Processing
                                40(5):R171.
Eliassen, R. and G. Tchobanoglous.   Removal  of  Nitrogen
and Phosphorus from Wastewater.   Environmental  Science
and Technology.  3^:536-541.   June  1969.

Eliassen, R., B. M. Wyckoff,  and  C.  D.  Tonkin.   Ion
Exchange for Reclamation of  Reusable  Supplies.   JAWWA.
57(9):1113-1122.   September  1965.
                               301

-------
 197.  Ember, L.  The Specter of  Cancer.   Environmental  Science
       and Technology.  9.( 1 3 ) : 111 6-1 1 21 .   December  1975.
 198.  Engineering Evaluation of  Virus  Hazard  in Water.  Journal
       of the Sanitary Engineering Division, ASCE.  96(SAl)-lli-
       160.   February 1970.                         —
 199.  England,  B.  Recovery of Viruses from Waste  and Other
       Waters by Chemical  Methods.   Developments in Industrial
       Microbiology.   15:174-183.  1973.
 200.  England,  B.,  ejt aj_.  Virologic Assessment of Sewage Treat-
       ment  at Santee, California.   In:  Transmission of Viruses
       by the Water  Route.  G. Berg,  ed.  John Wiley, New York
       pp.  401-417.   1965.
 201.  Englebrecht,  R.  S., e_t aK   New Microbial Indicators of
       Wastewater Chlorination Efficiency.   EPA-670/2-73-082
       February  1974.
 202.   English,  J. N. ,  e_t  aj[.   Deni trif ication in Granular Carbon
       and Sand  Columns.   JWPCF.   £6(l):28-42.   January 1974.
 203.   English,  J. N. ,  K.  D.  Linstedt,  and  E.  R.  Bennett.
       Research  Required to Establish Confidence in the Potable
       Reuse  of  Waste  Water.   U.S.  Environmental  Protection
       Agency, Cincinnati,  Ohio.   1975.
 204.   Ericsson,  B.  Nitrogen  Removal in a  Pilot Plant.   JWPCF
       4_7(4):727-740.  April  1975.
 205.   Esvelt, L. A., W. J.  Kaufman,  and R.  E.  Selleck.   Toxicity
       Assessment of Treated  Municipal  Wastewaters.   JWPCF
      15(7):1558-1572.  July  1973.
 206.   Evaluation of Municipal Sewage Treatment Alternatives
       NTIS/PB-233 489.  February  1974.
 207.   Evans, F.  L.  III.   Ozone Technology:   Current  Status.
      ]_n_:  Ozone in Water  and Wastewater Treatment.   Ann Arbor
      Science Publishers,  Ann Arbor, Michigan.   pp.  1-13.   1972.
208.  Evans, F.  L.  Ill,  e_t aj_.   Treatment  of  Urban Stormwater
      Runoff.  JWPCF.   40J5") :R162-R170.  May  1968.
209.  Evans, S.   Nitrate  Removal  by  Ion Exchange.   JWPCF  45(1)'
      632-636.  April  1973.                                — v  '*
210.  Fannin, K. F. ,  ejt afj..  Field Studies  on  Coliphages and
      Conforms  as Indicators of Airborne Animal Viral Contami-
      nation from Wastewater Treatment  Facilities   Water
      5rh«J5"Ch; DDK?*' uf Environmental Health and Epidemiology,
      School  of Public Health, University of Michigan, Ann      '
      Arbor.   (In press)
                              302

-------
211.   Fate of Organic Pesticides in the Aquatic Environment.
      Advances in Chemistry Series No.  111.   American Chemical
      Society, Washington,  D.C.   1972.

212.   Feinstone,  S.  M.,  A.  Z.  Kapikian, and  R.  H.  Purcell.
      Hepatitis A:   Detection  by Immune Electron Microscopy of
      a Viruslike Antigen Associated with Acute Illness.  Science,
      1_8_2:1026-1 028.   December 7, 1973.

213.   Ferens, M.  C.   A Review  of the Physiological Impact of
      Mercurials.  EPA-660/3-73-022.  February 1974.

214.   Ferguson, J.  F. and J.  Gavis.  A Review of the Arsenic
      Cycle in Natural  Waters.  Water Research.  6:1259-1274.
      1972.

215.   Ferguson, J.  F.,  D. Jenkins, and J. Eastman.  Calcium
      Phosphate Precipitation  at Slightly Alkaline pH Values.
      JWPCF.  45(4):620-631.   April 1973.

216.   Finberg, L.  Interaction of the Chemical Environment with
      the  Infant and Young Child.  Pediatrics.  53:831-837.
      1974.

217.   Focht,  D. D.   Microbial  Degradation of DDT Metabolites to
      Carbon  Dioxide, Water,  and Chloride.  Bulletin of  Environ-
      mental  Contamination and Toxicology.  _7_(1): 52-56.
      January  1972.

218.   Folk, G.  Phosphorus Removal with  Liquid Alum.    WPCF
      Highlights,  pp. 8-9,  February  1976.

219.   Folkman, Y. and A. M. Wachs.  Filtration  of Chlorella
      through  Dune-Sand.  Journal  of the  Sanitary Engineering
      Division, ASCE.  96JSA3):675-689.   June  1970.

220.   Foodborne and  Waterborne  Disease Outbreaks  Annual
      Summary  1973.  U.S. Center  for Disease Control,  HEW.
      1974.

221.   Foodborne  and  Waterborne  Disease Outbreaks  Annual  Summary
      1975.   U.S. Center for  Disease Control,  HEW.   September
      1976.

222.   Fossum,  G. 0.  Water Balance in  Sewage  Stabilization
      Lagoons.   NTIS/PB-233-482.   August 1971.

223.  Foster,  D. H.  and  R. S. Engelbrecht.   Microbial  Hazards
      in  Disposing of Wastewater on Soil.   In:   Conference  on
      Recycling  Treated  Municipal  Wastewater  through Forest  and
      Cropland.  W.  E.  Sopper and L. T.  Kardos,  eds.   EPA-660/2-
      74-003.  pp. 217-241.   March 1974.


                              303

-------
 224.  Frank, R., et a]_.  Organochlori ne  Insecticide  Residues  in
       Sediment andFish  Tissues,  Ontario,  Canada.  Pesticides
       Monitoring Journal.   7^:165-180.  March  1974.

 225.  Frissora, F. V.  An Advanced Water Filtration  Plant
       Water and Sewage Works.  UB(11):365-369.  November'1971.

 226.  Fulton, G.  P. and  E.   A. Bryant.  Pilot  Plant Program -
       Treatment of NYC Water Supply.   Civil Engineering - ASCE.
       46(6):52-55.

 227.  Furgason, R.  R.  and R. 0.  Day.   Iron and Manganese Removal
       with Ozone.   Part  I.   Water and  Sewage Works.  122(6)-42
       45-47.  June 1975.                              	       '

 228.  Furgason, R.  R.  and R. 0.  Day.    Iron and Manganese Removal
       with Ozone.   Part  II.   Water and Sewage Works.   122(7 :61-
       63,  July  1975.

 229.  Gaitan,  E.   Water-Borne Goitrogens  and their Role in the
       Etiology  of  Endemic Goiter.   World  Review of Nutrition
       and  Dietetics.   ]_£:53-90.   1973.

 230.  Gambrell, R.  p.  and S. B.  Weed.   The  Fate of Fertilizer
       Nutrients as  Related  to Water Quality in the North Carolina
       Coastal Plain.   NTIS/PB-238  001/2WP.   August 1974.

 231.   Ganczarczyk,  J.   Nitrogen  Transformation in Activated
       Sludge Treatment.   Journal of the Sanitary  Engineering
       Division, ASCE.  j)8(SA5):783.   October 1972.

 232.   Gangoli,  N.  and  G.  Thodos.   Phosphate Adsorption  Studies
       JWPCF.  i5(5):842-849.   May  1973.

 233.   Gavis, J.   Wastewater  Reuse.  National  Technical  Informa-
       tion Service, Springfield, Va.   1971.

 234.   Gavis, J.  and J. F. Ferguson.  The  Cycling  of Mercury
       through the Environment.  Water  Research.   6-989-1008
       1972.

235.  Geldreich, E.  E. and N. A.  Clarke.  The  Coliform Test-   A
      Criterion  for Viral Safety of Water.   In:   Proceedings
      13th Water Quality  Conference.   Urbana~Il 1 inois .  1971
      pp. 103-113.

236.  Geldreich, E.  E.  and A. Kenner.   Concepts of Fecal Strepto-
      cocci in Stream Pollution.   JWPCF.  41(8):R336-R352
      August 1969.                         —
                              304

-------
237.  Geldreich,  E.  E.  and R.  H.  Bordner.   Fecal Contamination
      of Fruits and  Vegetables during Cultivation and Processing
      for Market;  a  Review.   Journal  of Milk and Food Technology.
      34(4):184-195.   April  1971.

238.  George,  A.  and  0.  T. Zajicek.   Ion Exchange Equilibria.
      Chloride-Phosphate Exchange  with a Strong Base Anion
      Exchanger.   Environmental Science and Technology.  2(7)-
      540-542.   July  1968.                               ~

239.  Gerakis,  P.  A.  and A.  G. Sficas.  The Presence and Cycling
      of Pesticides  in the Ecosphere.  Residue Reviews.  52:69-
      87.  1974.                                          —

240.  Gerba, C. P.,  e_t aj_.  Adsorption of Poliovirus onto Acti-
      vated Carbon in Wastewater.   Environmental Science and
      Technology.  £:727-731.   August 1975.

241.  Gerba, C. P.,  e_t al_.  Enhancement of Poliovirus Adsorption
      in Wastewater  on Activated Carbon.  In:  Virus Survival
      in Water and Wastewater Systems.  MaTTna and Sagik, eds.
      Water Resources Symposium #7.   pp. 115-126.  1974.

242.  Gerba, C. P.,'c.  Wallis, and J. L. Melnick.  Viruses in
      Water:  The Problem, Some Solutions.  Environmental
      Science  and Technology.   9J13):1122-1126.  December 1975.

243.  Ghan, H.  B., C. Chen,  and R. P. Miele.  Disinfection and
      Color Removal  with Ozone (Draft Report).  EPA Advanced
      Waste Treatment Research Laboratory.  Cincinnati, Ohio.

244.  Ghan, H.  B. , e_t a_l_.  Wastewater Disinfection with Ozone
      Works Best with a Clean Effluent and Multiple, Low-Dosage
      Injection Points.   Bulletin  (California Water Pollution
      Control  Association).   j_2_(2) :47-53.  October 1975.

245.  Ghosh, M. M. and P.. D. Zugger.   Toxic Effects of Mercury
      on the Activated Sludge Process.  JWPCF.  45(3):424-433.
      March 1973.                                —

246.  Gibbs, R. J.  Mechanisms of  Trace Metal Transport in
      Rivers.   Science.   18£:71-73.   April 1973.

247.  Gilbert,  R.  G. , e_t al.  Wastewater Renovation and Reuse:
      Virus Removal  by SoTT Filtration.  Science.  192:1004-
      1005.  June 4,  1976.                         	

248.  Gilliam,  J.  W., R. B.  Daniels,  and J. F. Lutz.  Nitrogen
      Content  of Shallow Ground Water in the North Carolina
      Coastal  Plain.   Journal  of Environmental Quality.  3-147-
      151.   April  1974.                                   -
                             305

-------
249.  Giusti,  D. M.,  R.  A.  Conway,  and  C.  T.  Lawson.   Activated
      Carbon Adsorption  of  Petrochemicals.   JWPCF.   46(5) :947-
      965.  May  1974.

250.  Glaze, W.  H.  and J. E.  Henderson  IV.   Formation  of  Organo-
      chlorine Compounds  from  the  Chlorination  of  a  Municipal
      Secondary  Effluent.   JWPCF.   47(10):251-2515.   October
      1975.

251.  Glover,  G. E. and  G.  R.  Hubert.   Microstraining  and  Dis-
      infection  of  Combined  Sewer  Overflows  - Phase  II.   EPA-R2-
      73-124.  January 1973.

252.  Gloyna,  E. F.,  S.  0.  Brady,  and H.  Lyles.   Use  of Aerated
      Lagoons  and Ponds  in  Refinery and  Chemical  Waste Treatment.
      JWPCF.   41_(3):429-439.   March 1969.

253.  Godfrey, K. A., Jr.   Land Treatment  of  Municipal Sewage.
      Civil Engineering.  43_(9): 103-1 09.   September  1973.

254.  Goff, G. D. ,  ejt ajk   Emission of  Microbial  Aerosols  from
      Sewage Treatment Plants  that  use  Trickling  Filters.
      Health Service  Reports.   88^(7): 640-651 .   August-September
      1973.

255.  Gold, H. and  A. Todisco.  Wastewater Reuse  by  Continuous
      Ion Exchange.   In:  Complete  Water  Reuse.   L.  K. Cecil,
      ed.  American Institute  of Chemical  Engineers,  New  York,
      pp. 96-103.   1973.

256.  Goldman, J. C. , e± aj_-   Inorganic  Nitrogen  Removal  in a
      Combined Tertiary Treatment  Marine  Aquaculture  System - I:
      Removal  Efficiencies.   Water  Research.  8_:45-54.  1974.

257.  Goldman, J. C. , e± aj_.   Inorganic  Nitrogen  Removal  in a
      Combined Tertiary Treatment  Marine  Aquaculture  System -
      II:  Algal  Biomass.  Water Research.  §:55-59.   1974.

258.  Gossling, J.   and J. M. Slack.  Predominant Gram-Positive
      Bacteria in Human Feces:  Numbers,  Variety,  and  Persistence
      Infection and Immunity.  ^:719-729.  April  1974.

259.  Grabow,  W.  0. K.  The  Virology of Waste Water Treatment.
      Water Research.  2^(1 0): 675-701.    November 1968.

260.  Grabow,  W.  0. K. and E.  M. Nupen.    The  Load  of  Infectious
      Microorganisms  in the  Waste Water of Two  South African
      Hospitals.   Water Research.   £:1557-1563.  1972.

261.  Graeser, H. J.  Dallas'  Wastewater-Reclamation Studies.
      JAWWA.  63jlO):634-640.   October  1971.


                               306

-------
262.   Graeser, H.  J.   Water Reuse:  Resource of the Future.
      JAWWA.   (56_(10):575-578.   October 1974.

263.   Graetz, D.  A.,  L. C. Hammond, and J. M. Davidson.  Nitrate
      Movement in a Eustis Fine Sand Planted to Millet.  Soil
      and Crop Science Society of Florida.  Proceedings.  33:
      157-160.  November 27-29, 1973.

264.   Graetz, D.  A.,  ^t a_l_.  Parathion Degradation in  Lake
      Sediments.   JWPCF.  42^2) :R76-R94.  February 1970.

265.   Granata, A., ejt a_l_.  Relationship between Cancer Mortality
      and Urban Drinking Water Metal Ion  Content.  Minerva
      Medica.  61_:1941.  May 1970.

266.   Greenberg,  A. E. and E.  Kupka.  Tuberculosis Transmission
      by Waste Waters - A Review.   Sewage and  Industrial Wastes.
      i9(5):524-537.   May 1957.

267.   Gregg,  J. C.  Nitrate Removed  at Water Treatment Plant.
      Civil  Engineering - ASCE.   43_(4) :45-47.  April  1973.

268.   Gregor, C.  D.  Solubilization  of Lead  in Lakes  and
      Reservoir Sediments by NTA.   Environmental  Science and
      Technology.  6.(3) :278-279.   March 1972.

269.   Grigoropoulos, S. G., R. C.  Vidder, and  D.  W.  Max.  ^Fate
      of Aluminum-Precipitated Phosphorus in Activated Sludge
      and Anaerobic Digestion.   JWPCF.  43_(12) :2366-2382.
      December 1971.

270.   Grinstein, S. , J. L. Melnick,  and C.  Wallis.   Virus
      Isolations from  Sewage and  from  a Stream Receiving
      Effluents of Sewage  Treatment Plants.  Bulletin of  the
      World  Health Organization.   42^:291-296.  1970.

271.   Grover,  R.   Adsorption and  Desorption of Trifluralin,
      Triallate, and  Diallate  by  Various  Adsorbents.   Weed
      Science.  £2:405-408.  July 1974.

272.  Grover,  R. and  A.  E.  Smith.  Adsorption  Studies with the
      Acid and Dimethylamine  Forms of  2,4-D and  Dicambra.
      Canadian Journal  of Soil  Science.   5^:179-186.   May  1974.

273.  Gruenwald, A.   Drinking  Water from  Sewage?  The American
      City.   82(3):92-93.   March 1967.

274.  Gruninger,  R. M.  Chemical  Treatment for  Surface Water.
      Water  and  Sewage Works.   1_21_(6): 110-114.  June 1974.

275.  Gulledge,  J. H.  and J.  T.  O'Connor.  Removal of Arsenic
      (V)  from Water  by Adsorption on Aluminum and Ferric
      Hydroxides.  JAWWA.   6^(8):548-552.

                               307

-------
276.  Hager, D.  G.  Adsorption and Filtration with Granular
      Activated  Carbon.  Water and Wastes Engineering.  6^(8):
      39-43.  August 1969.

277.  Hager, D.  G. and P. B. Reilly.  Clarification-Adsorption
      in the Treatment of Municipal and Industrial Wastewater.
      JWPCF.  ^2_(5):794-800.  May 1970.

278.  Hager, D.  G. and M. E. Flentje.  Removal of Organic
      Contaminants by Granular-Carbon Filtration.  JAWWA.  57
      (11 ):1440-1450.  November 1965.

279.  Hall,  H.  E.  and G.  H.  Mauser.  Examination of Feces from
      Food Handlers for Salmonel1ae, Enteropathogenic E s c h e r i -
      chia coli,  and Clostridium perfrigens.  Applied Micro-
      FToTogy.   14(6):9280932.  November 1966.

280.  Hammer, M.  J.  Water and Waste-Water Technology.  Wiley,
      New York.   1975.

281.  Hamoda, M.  F. , e_t aj_.   Organics Removal by Low-Pressure
      Osmosis.   JWPCF.   4_5( 1 0) :2146-21 54.  October 1973.

282.  Hansen, R.  E.  Granular Carbon Filters for Taste and Odor
      Removal.   JAWWA.   64(3):176-181.  March 1972.

283.  Harris, W.  C.  Ozone Disinfection.  JAWWA.  £4(3): 182-183.
      March  1972.

284.  Harrison,  R. M.,  R. Perry, and R. A.  Wellings.  Polynuclear
      Aromatic  Hydrocarbons  in Raw, Potable and Waste Waters.
      Water  Research.  9^:331-346.  1975.

285.  Hatch, M.  J. and H. Wolochow.  Bacterial Survival:  Conse-
      quence of  the Airborne State.  In:  An Introduction to
      Experimental Aerobiology.   R. L. Dimmick and A. B. Akers,
      eds.   Wiley, New York.  pp. 267-295.   1969.

286.  Hauck, A.  R. and S. Sourirajan.  Performance of Porous
      Cellulose  Acetate Membranes for the Reverse Osmosis
      Treatment  of Hard and  Waste Waters.  Environmental Science
      and Technology.  1(12):1269-1275.

287.  Haug,  R. T.  and P.  L.  McCarty.  Nitrification with Sub-
      merged Filters.  JWPCF.  44(11):2086-2102.  November 1972.

288.  Heavy  Metals in the Environment.  Water Resources Research
      Institute,  Oregon State University, Corvallis, January
      1973.
                               308

-------
289.



290.


291.


292.



293.
294.
295.
296.
297.
 298.
 299.
           M.  L.  and T.  L.  Cox.   Effluent Water Treating
           International  Oil  Company's Houston Refinery.
AIChE Symposium Series.   69_(135) :151-153.  1973.
Hentschel ,
at Charter
Hepatitis Surveillance.   Center for Disease Control Report
37.   U.S. Public Health Service, HEW.   June 1975.

Hepatitis Surveillance.   Center for Disease Control Report
38.   U.S. Public Health Service, HEW.   September 1976.
Herrmann, 0. E,
Persistence of
Microbiology.
               , K. D. Kostenbader, and D. 0. Cliver.
               Enteroviruses in Lake Water.  Applied
               28:895-896.  November 1974.
 300.
Mickey, J. L. S. and P. C. Reist.  Health Significance
of Airborne Microorganisms from Wastewater Treatment
Processes.  Part I:  Summary of Investigations.  JWPCF.
47.(12):2741-2757.  December 1975.

Hindin, E. and  P. J. Bennett.  Water Reclamation by
Reverse Osmosis.  Water and Sewage Works.  116(2):66-73.
February  1969.

Hinesly,  T. D.,  0. D.  Braids, and J. E.  Molina.  Agricul
tural Benefits  and Environmental Changes  Resulting from
the Use of Digested Sewage Sludge on Field Crops.   An
Interim Report  on Solid Waste Demonstration  Project.
Environmental Protection  Agency.  1971.
Hoadley, A. W. and
of the Application
Civil Engineering,
Atlanta, Georgia.

Holzmacher, R. G.
Supply.  Water and
1971.
                    S. M.  Goyal.   Public  Health  Implications
                    of Wastewaters  to  the Land.   School  of
                    Georgia  Institute  of  Technology,
                    Nitrate  Removal  from  a  Ground  Water
                    Sewage Works.   1_]_8(7): 21 0-213.   July
 Horn,  L.  W.   Kinetics  of  Chlorine Disinfection  in an Eco-
 system.   Journal  of the  Sanitary Engineering  Division,
 ASCE.   9!3(SA1):183-193.   February 1972.

 Hook,  J.  E.,  L.  T.  Kardos,  and W. E.  Sopper,   Effects of
 Land  Disposal  of Wastewaters  on Soil  Phosphorus Relations
 In:   Conference  on  Recycling  Treated  Municipal  Wastewater
 through Forest and  Cropland.   W. E.  Sopper and  L. T.
 Kardos.   EPA-660/2-74-003.   pp. 179-195.   March 1974.
 Hornick,  R.  B.,  e_t a],
 Immunologic  Control.
 283:739-746.   October
                         Typhoid Fever:  Pathogenesis and
                       New England Journal  of Medicine.
                       1, 1970.
                                309

-------
301.   Hsu,  D.  Y.  and W.  0. Pipes.   Aluminum Hydroxide Effects
      on Wastewater Treatment Processes.  JWPCF.  45J4):681-697.
      April  1973.

302.   Huang, C.  H., D.  L.  Feuerstein, and E. L. Miller.  Demon-
      stration of  a High-Rate Activated Sludge System.  EPA-670/
      2-75-037.   March  1975.

303   Huang, C.  P.  and  M.  H. Wu.  Chromium Removal by Carbon
      Adsorption.   JWPCF.   4_7( 10): 2437-2446.  October 1975.

304.   Huang, P.  M.  and  C.  P. Hwang.  Inorganic and Organic
      Phosphorus  Distribution in Domestic and Municipal Sewage.
      Water and Sewage  Works.  l_2Cl(6): 82-83 .  June 1973.

305.   Hudson,  H.  E.  High-Quality Water Production and Viral
      Disease.  JAWWA.   54(10):1265-1274.  October 1962.

306.   Hueper,  W.  C. and W. W. Payne.  Carcinogenic Effects of
      Adsorbates  of Raw and Finished Water Supplies.  American
      Journal  of  Clinical  Pathology.  39_(5) :475-481 .  May  1963.

307.   Hulka, S.  C., e_t  aj_.  Sediment Coliform Populations  and
      Post  Chlorination Behavior of Wastewater Bacteria.    Water
      and Sewage  Works.   1_2J)(1 0): 79-81.  October  1973.

308.   Hume,  N. B.  and W.  F. Garber.  Marine Disposal  of
      Digested Screened Wastewater Solids.  Advances  in Water
      Pollution Research.   1966(3):243-262.

309.   Humenick,  M.  J.,  Jr. and J.  L. Schnoor.   Improving
      Mercury  (II)  Removal by Activated Carbon.   Journal of  the
      Environmental Engineering Division, ASCE.   100(EE6):1249-
      1262.   December 1974.

310.   Humenick, M.  J. and W. J.  Kaufman.  An  Integrated
      Biological-Chemical  Process for Municipal Wastewater
      Treatment.   Advances in Water Pollution  Research.   1970
      (1):I-19/1-18.

311.   Hunter,  J.  V. and T. A. Kotalik.  Chemical  and  Biological
      Quality  of Sewage Effluents.  In:  Conference on Recycling
      Treated  Municipal Wastewater through  Forest and Cropland.
      W. E.  Sopper and  L.  Kardos, eds.  EPA-660/2-74-003.
      pp. 6-27.  March 1974.

312.   Hunter,  J.  V. and H. Heukelekian.  The  Composition  of
      Domestic Sewage Fractions.  JWPCF.  37J8): 1142-1163.
      August  1965.

313.   Hunter,  J.  V., G. R. Bell, and C. N.  Henderson.  Coliform
      Organism Removals by Diatomite Filtration.   JAWWA.   58(9):
      1160-1169.   September  1966.

                              310

-------
314.   Mutton, W.  D.  and S.  A.  LaRocca.   Biological  Treatment of
      Concentrated Ammonia  Wastewaters.   JWPCF.   47(5):989-997.
      May 1975.

315.   Hyde, H.  C.  Sewage Sludge Utilization for Agricultural
      Soil Enrichment.   Presented at 7th Annual  Western
      Regional  Solid Waste  Symposium, April  7-8, 1975.

316.   Hyndshaw,  A. Y.   Activated Carbon to Remove Organic
      Contaminants from Water.  JAWWA.   64(5):309-311.  May
      1972.

317.   Identification of Organic Compounds in Effluents from
      Industrial  Sources.  EPA-68-01-2926.  April 1975.

318.   Imhoff, K., W. J. Muller, and D.  K. B. Thistlethwayte.
      Disposal  of Sewage and Other Water-Borne Wastes.  Ann
      Arbor Science Publishers, Ann Arbor, Michigan.   1974.

319.   Ingols, R.  S.  Chlorination of Water - Potable, Possibly:
      Wastewater, No!  Water and Sewage Works.    122(2):82-83.
      February 1975.

320.   Interaction of Heavy Metals and Biological Sewage Treat-
      ment Processes.  U.S. Public Health Service, Cincinnati,
      Ohio.  May  1965.

321.   Isensee, A. R. and G. E. Jones.  Distribution of 2,  3,  7,
      8-Tetrachlorodibenzo-p-dioxin  (TCDD) .in Aquatic Model
      Ecosystem.  Environmental Science  and  Technology.   9:688-
      672.   July  1975.

322.  Ishizaki,  C.  and J.  J.  Cookson, Jr.   Influence  of  Surface
      Oxides on  Adsorption and Catalysis  with Activated  Carbon.
      In:  Chemistry of  Water  Supply, Treatment, and  Distribution,
      J.  Rubin,  ed.  Ann Arbor Science  Publishers, Ann Arbor,
      Michigan.   pp. 201-231.  1975.

323.  Jamieson,  W.  Candida albicans as  an  Indicator  of  Pollu-
      tion in Estuarine  Water"!   PhD  Thesis.  New York University.
      1974.

324.  Jebens, H.  J. and  W.  C.  Boyle.   Enhanced  Phosphorus
      Removal in Trickling Filters.  Journal of the  Sanitary
      Engineering Division, ASCE.   98JSA3): 547-660.   June 1972.

325.  Jenkins, S.  R.,  J. Engeset,  and  V.  R.  Hasfurther.   Model
      Sand Filters  for the Removal  of  Colloidal  Manganese
      Oxides Using  Selected Cations  as  Filter  Aids.   In:
      Chemistry  of  Water Supply,  Treatment,  and Distribution.
      A.  J.  Rubin,  ed.   Ann Arbor  Science Publishers, Ann Arbor,
      Michigan,   pp.  181-199.   1975.

                               311

-------
326.  Jenne, E. A. and S. N. Luoma.  Forms of Trace Elements in
      Soils, Sediments, and Associated Waters:  An Overview of
      Their Determination and Biological Availability.  U.S.
      Geological Survey, Menlo Park, Ca.  1975.

327.  Jeris, J. S. and R. W. Owens.  Pilot-Scale High-Rate
      Biological Denitrification.  JUPCF.  47(8):2043-2057.
      August 1975.

328.  Jeris, J. S., C. Beer, and J. A. Mueller.  High Rate
      Biological Denitrification Using a Granular Fluidized
      Bed.  JWPCF.  4£(9):2118-2128.  September 1974.

329.  Jernelov, A. and S. Jensen.  Biological Methylation of
      Mercury in Aquatic Organisms.  Nature.  223:753-754.
      August 1969.

330.  Jewell, W. J. and R.  J. Cummings.   Denitrification of
      Concentrated Nitrate Wastewaters.   JWPCF.  4_5_(9): 2281-
      2291.  September 1975.

331.  Johnson,  E.  L., J. H. Beeghly, and R.  F. Wukasch.   Phos-
      phorus Removal  with Iron and Polyelectrolytes.  Public
      Works.  l_00:66-68, 142.  November 1969.

332.  Johnson,  J.  D.   Disinfection:  Water and Wastewater.  Ann
      Arbor Science Publishers, Ann Arbor, Michigan.  1975.

333.  Johnson,  J.  E.   The Public Health Implications of Wide-
      spread Use of the Phenoxy Herbicides and Picloram.
      Bio-Science.  £]_( 1 7) :899-905.  September 1971.

334.  Jolley, R. L.  Chlorine-Containing Organic Constituents
      in Chlorinated Effluents.  JWPCF.   47_(3) :601-618.   March
      1975.

335.  Jordan, T. A.,  M. M.  Ghosh, and R. H.  Boyd,  Jr.  Physico-
      Chemical  Aspects of Deep-Bed Filtration.  JWPCF.  46^(12):
      2745-2754.  December 1974.

336.  Kalinske, A. A.  Enhancement of Biological Oxidation of
      Organic Wastes Using Activated Carbon in Microbial Suspen-
      sions.  Water and Sewage Works.  119(6) :62-64.  June 1972.

337.  Kampelmacher, E. H. and L. M. van Noorle Jansen.  Occur-
      rence of Salmonella in Oxidation Ditches.  JWPCF.   4_5(2):
      348-352.   February 1973.

338.  Kampelmacher, E. H. and L. M. van Noorle Jansen.  Reduction
      of Bacteria  in Sludge Treatment.  JWPCF.  44(2):309-313.
      February 1972.
                               312

-------
339.
340.
341.
342.
343.
344.
345.
346.
347.
348.
349.
350.
Kampelmacher,  E.
Salmonella - Its
System.   JWPCF.
H. and  L. M.  van  Noorle  Jansen.
Presence  in  and Removal  from  a  Wastewater
42(12):2069-2073.   December  1970.
Kanisawa, M.  and H.  A.  Schroeder.  Life Term Studies on
the Effects of Arsenic, Germanium, Tin, and Vanadium on
Spontaneous Tumors in Mice.  Cancer Research.  27:1192-1195,
July 1967.

Kapikian, A.  Z. , et al.  Visualization by Immune Electron
Microscopy of a 27^"nm Particle Associated with Acute
Infectious Nonbacterial Gastroenteritis.  Journal of
Virology.  10:1075-1081.  1972.
Kardos, L. T. ,  e_t al.
for Reuse as a  Water
February 1974.
       Renovation  of  Secondary  Effluent
     Resource.   EPA-660/2-74-016.
Katzenelson, E., B. Kletter, and H. I. Shuval .   Inactiva-
tion Kinetics of Viruses and Bacteria in Water by Use of
Ozone.  JAWWA.  66:725-729.  December 1974.

Katzenelson, E. , e_t al.  Inactivation of Viruses and
Bacteria by Ozone.  Tin:  Chemistry of Water Supply,
Treatment, and  Distribution.  A. J. Rubin, ed.   Ann Arbor
Science Publishers, Ann Arbor, Michigan,   pp. 409-421.
1975.

Keeney, D. R.,  K. W. Lee, and L. M. Walsh.  Guidelines  for
the Application of Wastewater Sludge  to Agricultural  Land
in Wisconsin.   Technical Bulletin  No. 88.  Department of
Natural Resources.  Mad'ison, Wisconsin.  1975.

Kenard, R. P. and R. S. Valentine.  Rapid  Determination of
the Presence of Enteric Bacteria in Water.  Applied
Microbiology.   2^(3)-.484-487.   1974.

Kenline, P. A.  and  P.  V. Scarpino.  Bacterial Air Pollu-
tion from Sewage Treatment  Plants.  American Industrial
Hygiene Association Journal.  33:346-352.  May 1972.
Kerfoot, W. B. and B. T.
Renovation and Retrieval
and Conservation.  Woods
February 1974.
         Ketchum.  Cape Cod
         System, a Study of
         Hole Oceanographic
Waste Water
Water Treatment
Institution.
Ketchum, L. H. ,
Stormwaters and
53-62.  January
Jr.  and W.  J. Weber, Jr.  Coagulation of
Low Alkalinity Wastewaters.  JWPCF.  46(1)
King, P. H., et al.   Distribution  of  Pesticides  in Surface
Waters.  JAWWAT ~Tl_(9):483-486.  September  1969.
                              313

-------
351.  "c/;nu, • , R. N.  Ozone in Water Disinfection.  In :  Ozone
       n '..Vter and Wastewater Treatment.  Ann Arbor Science
      ?i'o': ishers, Ann Arbor, Michigan.  pp. 123-143.  1973.

352.  Kinoshita, S. and T. Sunada.  On the Treatment  of Poly-
      chlorinated Biphenyl in Water by Ionizing Radiation.  In :
      Advances in Wastewater Research.  Pergamon Press, New York
               -e.   1972.
353.  Kirk, B. S., R. McNabney, and C. S. Wynn.  Pilot Plant
      Studies of Tertiary Wastewater Treatment with Ozone.  In :
      Ozone in Water and Wastewater Treatment.  Ann Arbor Science
      Publishers, Ann Arbor, Michigan,  pp. 61-82.  1972.

354.  Kirkham, M. B.  and G.  K.  Dotson.  Growth of Barley Irri-
      gated with Wastewater Sludge Containing Phosphate
      Precipitants.   Proceedings of the National Conference on
      Municipal  Sludge Management,  pp. 97-106.  June 11-13,
      1974.

355.  Klein, L.  A.,  et^ ^]_.   Sources of Metal in New York City
      Wastewater.  Metal Finishing.  7^:34-35.  July 1974.

356.  Klein, S.  A.   NTA Removal in Septic Tank and Oxidation
      Pond Systems.   JWPCF.   46(l):78-88.  January 1974.

357.  Klock, J.  W.   Survival of Coliform Bacteria in Wastewater
      Treatment  Lagoons.  JWPCF.  43_( 1 0) : 2071 -2083.  October
      1971.

358.  Knittel, M. D.   Occurrence of Klebsiella pneumoniae in
      Surface Waters.  Applied Microbiology.  29^( 5 ): 595-597 .
      May 1975.

359.  Koerts, K.  Selective Removal of Mercury, Lead, Zinc,
      Copper, and Silver.   In:   Proceedings of the Second
      National Conference on Complete Water Reuse.  American
      Institute  of Chemical  Engineers, New York, 1975.   pp. 260-
      262.

360   Kokoropoulos ,  P.  Designing Post-Chlorination by Chemical
      Reactor Approach.  JWPCF.  4_5(1 0) : 21 55-21 65.  October 1973.

361.  Kokoropoulos,  P. and  G.  P. Manos.  Kinetics as Design
      Criteria for Post Chlori  nation.  Journal of the Environ-
      mental Engineering Division, ASCE.  ^£(EE1 ): 73-88.
      February 1973.

362.  Koon, J. H. and W. J.  Kaufman.  Ammonia Removal from
      Municipal  Wastewaters by  Ion Exchange.  JWPCF.  47(3) :
      448-465.  March 1975.
                               314

-------
363.
364.


365.
366.
367.
368.
370.
371.
 372.
 373.
 374.
Kopp,  J.  F.   The Occurrence of Trace Elements in Water.
Proceedings  of the Third Annual  Conference on Trace Sub-
stances in Environmental Health.   University of Missouri,
Columbia.   D.  D. Hemphill, ed.  pp.  59-73.  1969.

Kott,  Y.,  e_t aj_.  Bacteriophages as  Viral Pollution
Indicators.   Water Research.  8^(3) :165-171.   1974.

Kruse, C.  W.,  V. P. Oliveri, and K.  Kawata.   The Enhance-
ment of Viral  Inactivation of Halogens.  Proceedings
Thirteenth Quality Conference; Virus and Water Quality:
Occurrence and Control.  University of Illinois,  pp. 197-
209.  February 1971.

Kuiper, 0. and R. Wechsler.   Domestic Waste Water Re-Use
Aspects of the Treatment System.  Water  Research.  9:655-
657.  1975.
Labadie, 0.
of Combined
1973.
            W.   Optimization
            Sewer Overflow.
Technique for Minimization
NTIS/PB-234 331/7WP.  June
Lager, J. A. and W. G. Smith.  Urban  Stormwater  Management
and Technology:  An Assessment.   EPA-670/2-74-040.
December 1974.
369.  Lance, J. C., C. P. Gerba, and  J.  L.  Melnick.   Virus
      Movement in Soil Columns  Flooded with Secondary Sewage
      Effluent.  Applied and Environmental  Microbiology.   32(4):
      520-526.  October 1976.                              —
Lanouette,  K.
Environmental
1972.
              H.   Removing Heavy Metals from Waste Water.
              Science and Technology.  6^(6) :518-522.  June
Larson, T.  J.  and D.  G.  Argo.  Large Scale
tion by Reverse Osmosis.  Presented at the
tion Conference of the American Continent,
October 24-29, 1976.
                                            Water Reclama-
                                            First Desalina-
                                            Mexico City,
 Lawrence,  A.  W.   Kinetics  of  Microbiological ly Mediated
 Transformations  of  Heavy Metals  in  Aquatic  Environments.
 NTIS/PB-239  148.  June  1974.

 Lawrence,  J.  and H.  M.  Tosine.   Adsorption  of Poly-
 chlorinated  Biphenyls  from Aqueous  Solutio.ns  and Sewage.
 Environmental  Science  and  Technology.   10(4) -.381-383.
 April  1976.

 Lawrence,  J.  and H.  W.  Zimmermann.   Potable Water Treat-
 ment  for Some Asbestiform  Minerals:  Optimization and
 Turbidity Data..   Water  Research.  1_0:195-198.   1976.
                                315

-------
 375.   Lawrence,  J.,  ejt  aj..   Removal  of Asbestos  Fibres  from
       Potable  Water  by  Coagulation and Filtration.   Water
       Research.   _9:397-400.   1975.

 376.   Leary, R.  D.   Two-Hundred  MGD  Activated  Sludge Plant
       Removes  Phosphorus  by  Pickle Liquor.   EPA-670/2-73-050.
       September  1973.

 377.   Lee,  J.  A., et al.   Filtering  Combined Sewer  Overflows
       JWPCF.   44(7771317-1333.   July 1972.

 378.   Lee,  P.  E.  Activated  Carbon  Removes  Sulfide  Odor.   Water
       and Sewage  Works.   j_2J_(9): 11 6-11 7.   September 1974.

 379.   LeGendre,  G. R. and  D.  D.  Runnels.   Removal of Dissolved
       Molybdenum  from Wastewaters  by Precipitates of Iron.
       Environmental  Science  and  Technology.  9.: 74.4-749.   August
       I .7 / 0 «

 380.   Leigh, G. M.   Degradation  of Selected  Chlorinated  Hydro-
       carbon Insecticides.   JWPCF.   41(11):R450-R460.   November
       1969.                          ~~

 381.   Leland,  H.  V., W.  N. Bruce, and  N.  F.  Shimp.   Chlorinated
       Hydrocarbon Insecticides in Sediments  of Southern  Lake
       Michigan.   Environmental Science and Technology.   7(9):833.
       838.   September 1973.

 382.   Leland,  H.  V., S.  S. Shukla, and N. F. Shimp.   Factors
      Affecting Distribution of  Lead and  Other Trace  Elements
       in  Sediments of Southern Lake  Michigan.  In:   Trace  Metals
      and Metal-Organic  Interactions in Natural Waters.   P. C.
      Singer, ed.  Ann Arbor Science Publishers, Ann  Arbor,
      Michigan,  pp.  89-129.   1974.

 383.  Lennette, E. H., E.  H.  Spaulding and J. P.  Truant.   Manual
      of  Clinical Microbiology.  2nd edition.  American  Society
      for Microbiology,  Washington,  D.C., 1974.

 384.  Lerman, A.  and C.  W. Childs.   Metal-Organic Complexes in
      Natural Waters:  Control of Distribution by Thermodynamic,
      Kinetic and Physical Factors.  In:  Trace Metals and  Metal-
      Organic Interactions in Natural Waters.  Ann  Arbor Science
      Publishers, Ann Arbor,  Michigan,  pp.  201-235.  1974.

385.  Leshniowsky, W. 0.,  ejt  aJL   Aldrin:  Removal  from Lake
      Water by  Flocculent  Bacteria.  Science.  169(3949):993-
      995.   September 4, 1970.

386.  Levin, G. V. and J.  Shapiro.  Metabolic Uptake of Phos-
      phorus by Wastewater Organisms.  JWPCF.  37(6):800-818.
      June  1965.


                              316

-------
387.   Lin, S.  S.  and D.  A.  Carlson.   Phosphorus Removal by the
      Addition of Aluminum (III) to the Activated Sludge Process.
      JWPCF.   47_(7): 1978-1 986.   July 1975.

388.   Lindsay, W. L.  Inorganic Reactions of Sewage Wastes with
      Soils.   In;  Recycling Municipal  Sludges and Effluents on
      Land; Proceedings of the Joint Conference, July 9-13, 1973.
      pp. 91-96.

389.   Lindstedt, K. D. and E. R. Bennett.  Evaluation of Treat-
      ment for Urban Wastewater Reuse.   EPA-R2-73-122.  July
      1973.

390.   Lindstedt, K. D., E. R. Bennett,  and S. W. Work.  Quality
      Considerations in Successive Water  Use.  JWPCF.  43(8):
      1681-1694.  August 1971.

391.   Lindstedt, K. D., C. P. Houck, and  J. T. O'Connor.   Trace
      Element Removals in Advanced Wastewater Treatment Processes
      JWPCF.  43J7):1507-1513.  July 1971.

392.   Lingle, J. W. and E. R. Hermann.   Mercury  in Anaerobic
      Sludge  Digestion.  JWPCF.  4_M3) :466-471 .  March  1975.

393.   Loehr,  R.  C.  and C. T. deNavarra, Jr.   Grease  Removal at
      a  Municipal  Treatment  Facility.  JWPCF.  4J_(5): R142-R1 54.
      May  1969.

394.   Logsdon, G.  S.  and J.  M.  Symons.  Mercury  Removal by
      Conventional  Water-Treatment  Techniques.   JAWWA.  65(8):
      554-562.   August 1973.

395.  Logsdon, G.  S.  and  E.  Edgerley,  Jr.   Sludge  Dewatering  by
      Freezing.   JAWWA.   63_(11) :734-740.   November 1971.

396.  Logsdon,  G.  S.,  T.  S.  Sarg,  and  J.  M.  Symons.   Removal  of
      Heavy Metals  by  Conventional  Treatment.   In:   Proceedings,
      16th Water Quality  Conference, University  of Illinois at
      Urbana-Champaign.   1974.   pp.  111-133.

397.  Long, D.  A.  and  J.  B.  Nesbitt.   Removal  of Soluble  Phos-
      phorus  in  an Activated Sludge Plant.   JWPCF.  47(1):170-
      184.  January 1975.

398.  Long, D.  A., J.  R.  Nesbitt,  and  R.  R.  Kountz.   Soluble
      Phosphorus Removal  in the Activated Sludge Process.  Part
       I.  Water Quality  Office, U.S.  Environmental Protection
      Agency.  August 1971.

399.   Long, W.  N.  and F.  A.  Bell,  Jr.   Health Factors and
       Reused  Waters.   JAWWA.  64.(4) :220-225.  April 1972.
                               317

-------
400.   Longley,  E.,  e_t  aj_.   Enhancement  of  Terminal  Disinfection
       of a Wastewater  Treatment  System.   In:   Virus  Survival  by
       Water  and Wastewater  Systems.   Malina  and  Sagik,  eds.
       Water  Resources  Symposium  #7.   pp.  166-179.   1974.

401.   Lothrop,  T.  L. and  0.  J. Sprout.   High-level  Inactivation
       of Viruses  in  Wastewater by  Chiorination.   JWPCF.   41(4):
       567-575.  April  1969.

402.   Lowndes,  M.  R.   Ozone  for  Water and  Effluent  Treatment.
       Chemistry and  Industry.  ^4:951-956.   August  21,  1971.

403.   Ludzack,  F.  J. and  D.  K. Noran.   Tolerance  of  High
       Salinities  by  Conventional Wastewater  Treatment  Processes.
       JWPCF.  37^(10):1404-1416.  October  1965.

404.   Lund,  E.  Inactivation of  Viruses.   Progress  in  Water
       Technology.  .3:95-97.  1973.

405.   Lutin, P. A.   Removal  of Organic  Nitrites  from Wastewater
       Systems.  JWPCF.   4^(9):1632-1642.   September  1970.

406.   Mackenthern, K. M.  Nitrogen and  Phosphorus in Water:   An
       Annotated Selected  Bibliography of Their Biological
       Effects.  U.S. Public  Health Service.  Division  of  Water
       Supply and Pollution Control.   1965.

407.   Mackenthern, K. M.  and L.  E. Keup.   Biological Problems
       Encountered in Water Supplies.  JAWWA.   6^(8):520-526.
       August 1970.

408.  MacKenzie, R. D., e_t aj,.    Chronic Toxicity  Studies.   II:
       Hexavalent and Trivalent Chromium Administered in Drinking
       Water to Rats.  AMA Archives of Industrial  Health.   1_8:
       232-234.  1958.

409.  Majumdar, S. B.,  e_t aj_.  Inactivation  of Poliovirus  in
       Water by Ozonation.   JWPCF.  4^(12):2433-2443.   December
       1973.

410.   Malaney, G.  W., et_  aj_.  Resistance of  Carcinogenic  Organic
       Compounds to Oxidation by  Activated  Sludge.  JWPCF.  39
       (12):2020-2029.  December  1967.

411.   Malina, J. F., e_t aj_.  Poliovirus  Inactivation by Activated
       Sludge.  In:  VTrus Survival in Water  and Wastewater
       Systems. "Ralina  &  Sagik,  eds.  Water  Resources  Symposium
       #7.   pp. 95-106.   1974.

412.   Malina, J. F., e£ al.  Poliovirus  Inactivation by Activated
       Sludge.  JWPCF.  47J8):2178-2183.  August  1975.


                               318

-------
413.   Malone, J.  R.  and T.  L.  Bailey.  Oxidation Ponds Remove
      Bacteria.   Water and  Sewage Works.  116(4):136-140.  April
      1969.

414.   Mangravite, F. J., Jr.,  e_t aj_.  Removal of Humic Acid by
      Coagulation and Microf 1 otation.  JAWWA.  67^(2): 88-94.
      February 1975.

415.   Manske, D.  D.  and P.  E.  Corneliussen.  Pesticide Residues
      in Total Diet Samples (VII).   Pesticides Monitoring
      Journal.  8i(2): 110-124.   September 1974.

416.   Manwaring,  J.  F.  Removal of  Viruses by Coagulation  and
      Flocculation.   JAWWA.  6,3(5) :298-300.  May 1971.

417.   Mara, D. D.   Fecal Bacterial  Kinetics  in Stabilization
      Ponds.  Journal of the Environmental Engineering Division,
      ASCE.  100(EE5):1191-1192.  October  1974.

418.   Marais, G.  V.  R.  Faecal Bacterial Kinetics  in  Stabiliza-
      tion Ponds.   Journal  of the Environmental  Engineering
      Division, ASCE.   1_00(EE1 ): 119-1 39.   February  1974.

419.   Maruyama, T., S.  A.  Hannah, and J. M.  Cohen.   Metal
      Removal by Physical  and Chemical  Treatment Processes.
      JWPCF.  £7_:962-975.  May  1973.

420.   Marx,  J. L.   Drinking Water:   Another  Source  of Carcino-
      gens.   Science.   86^809-811.   November 1974.

421.  Matsumura,  F.,  Y. Gotoh,  and  G. M.  Boush.  Factors
      Influencing Translocation  and Transformation  of Mercury
      in  River Sediment.   Bulletin  of Environmental Contamina-
      tion  and Toxicology.  8(5):267-272.   November 1972.

422.  Mattson, J. S.  and F. W.  Kennedy.   Evaluation Criteria for
      Granular Activated Carbons.   JWPCF.   43_(11 ): 2210-2217.
      November 1971.

423.  Maxwell, K.  E.   Environment of Life.  Dickenson Publishing
      Company, Encino,  Ca.  1976.

424.  Mayer,  B.  W.  and N.  Schlackman.  Organo-phosphates - A
      Pediatric  Hazard. American Family Physician.  !_]_( 5) : 1 21 -
      124.   May  1975.

425.  Mayrose,  D.  F.   Heat Treatment and Incineration.  Pro-
      ceedings of the National  Conference on Municipal  Sludge
      Management.   pp.  87-91.   June 11-13,  1974.

 426.  McAchran,  G.  E. and  R.  D., Hogue.   Phosphate  Removal from
      Municipal  Sewage.  Water and  Sewage Works.   118(2):36-39.
       February 1971.

                               319

-------
427.   McCarthy,  J.  J.  and  C.  H.  Smith..  A  Review  of  Ozone  and
       Its Application  to  Domestic  Wastewater  Treatment.  JAWWA.
       .66:718-725.   December  1974.

428.   McCarty, P.  L.   Biological Processes  for  Nitrogen  Removal  -
       Theory and Application.   Proceedings  Twelfth Sanitary
       Engineering  Conference;  Nitrate  and  Water Supply:  Source
       and Control.  University of  Illinois.   pp.  136-152.
       February 1970.

429.   McClanahan,  M. A.   Recycle -  What  Disinfectant for Safe
       Water Then?   In:  Johnson, J.  D.   Disinfection - Water
       and Wastewater.  Ann Arbor Science Publishers, Ann Arbor,
       Michigan,  1975.  pp. 49-66.

430.   McDermott, G. N., e_t aj_.   Effects  of  Copper on Aerobic
       Biological Sewage Treatment.   JWPCF.  3j>.(2):227-241.
       February 1963.

431.   McDermott, G. N. , ejt aj_.   Ni'ckel in  Relation to Activated
       Sludge and Anaerobic Digestion Process.   JWPCF.  37(2);
       163-177.   February  1965.

432.   McGarry, M.  G.   Algal  Flocculation with Aluminum Sulfate
       and Polyelectrolytes.   JWPCF.  42_(5): R191-R201.  May  1970.

433.   McGregor, W.  C.  and R.  K.  Finn.  Factors  Affecting the
       Flocculation  of  Bacteria  by  Chemical  Additives.  Biotech-
       nology and Bioengineering.   1_]_(2): 1 27-138.  March  1969.

434.   McGuire, J.  H.,  A. L.  Alford,  and  M.  H. Carter.  Organic
       Pollutant  Identification  Utilizing Mass Spectrometry.
       EPA-R2-73-234.   July 1973.

435.   Mclndoe, R.  W. Diatomaceous  Earth  Filtration for Water
       Supplies/2.   Water and  Wastes  Engineering.  6.(11) :48-52.
       November 1969.

436.  McKee, J. E.  and H. W.  Wolf.   Water  Quality Criteria.
       2nd edition.California  State  Water Quality  Board,  1963.

437.  McKee, J. E., C. H. Brokaw,  and  R. T. Mclaughlin.  Chemical
      and Colicidal Effects  of  Halogens  in  Sewage.   JWPCF.
       3_2(8):795-819.   August  1960.

438.  McKendrick,  J.,  G. R.  Bates,  and E.  R. Swart.   The Physico-
       Chemical Treatment of  Crude  Sewage.   Water  Pollution
       Control.  74(2):155-159.   1975.

439.  McLean, D.  M., J. R. Brown,  and  R. Laak.  Virus  Dispersal
       by Water.  JAWWA.  58(7):920-928.  July 1966.


                               320

-------
440.   McLellon,  M.,  T.  M.  Kunath,  and C.  Chao.   Coagulation of
      Colloidal- and Solution-Phase Impurities  in Trickling
      Filter Effluents.   JWPCF.  44(1 ): 77-91.   January 1972.

441.   McMichael, F.  C.  and J.  E.  McKee.  Wastewater Reclamation
      at Whittier Narrows, California.   California Institute
      of Technology.  September 30, 1965.

442.   Medlar, S.  Operating Experiences with Activated
   •   Granular Carbon.   Water and Sewage Works.  122(2):70-73.
      February 1975.

443.   Mennell, M. , e_t a_]_.   Treatment of Primary  Effluent by Lime
      Precipitation  and Dissolved Air Flotation.  JWPCF.  46(11):
      2472-2485.  November 1974.

444.   Mercado-Burgos, N.,  R.  C. Hoehn,  and R.  B. Holliman.
      Effect of Halogens and Ozone on Schistosoma Ova.  JWPCF.
      £7(10):2411-2419.   October 1974.

445.   Mercer, B. W., et al.  Ammonia Removal from Secondary
      Effluents by Selective Ion Exchange.  JWPCF.  4_2(2):R95-
      R107.  February 1970.

446.   Merrell, J. C. and A. Katko.  Reclaimed Wastewater for
      Santee Recreational  Lakes.  JWPCF.  38^(8): 131 0-1318.
      August 1966.

447.   Merrell, J. C. and P. C. Ward.  Virus Control at  the
      Santee, California Project.  JAWWA.   61_(2): 145-1 53.
      February 1968.

448.   Merson, M. H.  and W. H.  Barker, Jr.   Outbreaks  of Water-
      borne  Disease in  the United States, 1971-1972.   Journal
      of Infectious Diseases.  1_2£(5) :614-616.   May 1974.
                                i
449.   Merten, U. and D. T. Bray.   Reverse Osmosis for Water
      Reclamation.  Advances in Water  Pollution  Research.   1966
      (3):315-331.

450.   Metzler,  D. F. , e_t  
-------
453.  Mitchell, F. K.  Comparison of Primary and Secondary
      Treatment.  Southern California Coastal Water Research
      Project Annual Report.  El Segundo, Ca.  pp. 163-165.
      June 30, 1974.

454.  Monroe, D. W.  and D. C. Phillips.  Chlorine Disinfection
      in Final Settling Basins.  Journal of the Sanitary
      Engineering Division, ASCE.  9_8(SA2) : 287-297.  April 1972.

455.  Montalvo, J. G., Jr. and C. G. Lee.  Analytical Notes -
      Removal of Organics from Water:  Evaluating Activated
      Carbon.  JAWWA.  £8(4):211-215.  April 1976.

456.  Moore, W. A.,  e_t aj_.  Effects of Chromium on the Activated
      Sludge Process.  JWPCF.  33. (1): 54-72.  January 1961.

457.  Morbidity and  Mortality Weekly Report.  U.S. Center for
      Disease Control, HEW.  2^(34).  August 24, 1974.

458.  Morbidity and  Mortality Weekly Report.  U.S. Center for
      Disease Control, HEW.  ^4_(28).  July 12, 1975.

459.  Morbidity and  Mortality Weekly Report.  U.S. Center for
      Disease Control, HEW.  2^4(29).  July 19, 1975.

460.  Morbidity and  Mortality Weekly Report.  U.S. Center for
      Disease Control, HEW.  24_(43).  October 1975.

461.  Morel, F., R.  E. McDuff, and J. J. Morgan.  Interactions
      and Chemostasis in Aquatic Chemical Systems:  Role of pH,
      pE, Solubility, and Complexation.  In:  Trace Metals and
      Metal-Organic  Interactions in Natural Waters.  P. C.
      Singer, ed.   Ann Arbor Science Publishers, Ann Arbor,
      Michigan.  pp. 157-200.  1974.

462.  Morgan, J.  J.   Physica1-Chemical Forms of Chromium in
      Sewers, Treatment Works, and Coastal Water Environments
      (Personal Communication).  1975.

463.  Morris, J.  C.   Chlorination and Disinfection - State of
      the Art.  JAWWA.  61( 12):769-774.  December 1971.

464.  Morris, J.  C.   Formation of Halogenated Organics by
      Chlorination of Water Supplies (A Review).  EPA-600/1-75-
      002.   March 1975.

465.  Morris, J.  C.   The Role of Ozone in Water Treatment.  In:
      Proceedings, 96th Annual Conference American Water Works
      Association.  June 20-25, 1976.  29-6.

466.  Morris, R. L., L. G. Johnson, and D. W. Ebert.  Pesticides
      and Heavy Metals in the Aquatic Environment.  Health
      Laboratory Science.  2:145-151.  April 1972.
                               322

-------
467.   Morton, S.  D.  and E.  W. Sawyer.  Clay Minerals Remove
      Organics, Viruses and Heavy Metals from Water.  Water and
      Sewage Works.   Reference Issue:  116-120.  April 30, 1976.

468.   Mosley, J.  W.   Transmission of Viral Diseases by Drinking
      Water.  In:   Transmission of Viruses by the Water Route.
      G. Berg, ed.  Wiley,  New York.  pp. 5-23.  1965..

469.   Murphy, K.  L.   Gamma  Radiation as an Effective Disinfec-
      tant.  Water and Pollution Control.  112(4):24-28.  April
      1974.

470.   Muzzarelli,  R. A.  Selective Collection of Trace Metal
      Ions by Precipitation of Chitosan, and New Derivatives  of
      Chitosan.  Analytica Chimica Acta.  ^4_:133-142.  1971.

471.   Mytelka, A.  I., e_t al.  Heavy  Metals in Wastewater  and
      Treatment Plant Effluents.  JWPCF.  45(9):1859-1864.
      September 1973.

472.   Napolitano, P. J. and  D. R. Rowe.  Microbial  Content  of
      Air  Near Sewage Treatment Plants.  Water  and  Sewage Works.
      1J_3( 12)-.480-483.  December 1966.

473.   National Emissions Inventory  of  Sources  and  Emissions  of
      Chromium.   EPA-450/3-74-012.   May  1973.

474.  Nebel,  C.,  et  al.  Ozone Disinfection  of  Industrial-
      Municipal Secondary  Effluents.   JWPCF.   4J>(12) :2493-2507.
      December 1973.

475.  Nelson,  D.  W.,  L. B.  Owens, and  R.  E.  Terry.   Denitrifi-
      cation  as a Pathway  for Nitrate  Removal  in Aquatic
      Systems.  NTIS/PB-231  305/4WP.   December 1973.

476.  Neufeld, R. D.  and E.  R.  Hermann.   Heavy Metal  Removal  by
      Acclimated  Activated Sludge.   JWPCF.   47(2):310-329.
      February 1975.

477.  New Process Detoxifies Cyanide Wastes.  Environmental
      Science and Technology.  5^(6) :496-497.  June 1971.

478.  Newton, C.  D., W.  W. Shephard, and M.  S.  Coleman.   Street
      Runoff as a Source  of Lead Pollution.   JWPCF.  46(5):999-
       1000.   May  1974.

479.  Nickerson,  G.  L.,  ejt aj_.  Chemical Addition to Trickling
       Filter Plants.  JWPCF.  46^(1): 133-147.  January 1974.

480.   Nilsson, R.  Removal of Metals by Chemical Treatment of
       Municipal  Waste Water.  Water Research.   5:51-60.  1971.
                                323

-------
 481.   Nisbet,  I.  C.  T.   Criteria Document for PCB's.   EPA-440/9-
       76-021.   July  1976.

 482.   Nisbet,  I.  C.  T.  and  A.  F. Sarofim.   Rates and  Routes  of
       Transport of PCB's  in the Environment.   Environmental
       Health  Perspectives.   ^:21-38.   April  1972.

 483.   Nitrification  and Denitrification  Facilities:   Wastewater
       Treatment.. EPA  Technology Transfer.   August  1973.

 484.   Nitrogenous Compounds in  the  Environment.   EPA-5AB-73-001
       December  1973.

 485.   Noland, R.  F.  and R.  Birkbeck.   Two-Stage  Biological
       Process Provides  High Degree  of  Treatment.   1973  Water
       Pollution Control Conference.  Cleveland,  Ohio.   October
       2,  1973.

 486.   Nomura, M.  M.  and R.  H. F.  Young.   Fate  of Heavy  Metals
       in  the Sewage  Treatment °rocess.   Water  Resources  Research
       Center Technical  Report No. 82.  University of  Hawaii,
       Honolulu.   September  1974.

 487.   Nupen, E. M.   Virus Studies on the Windhoek Wastewater
       Reclamation  Plant (South-West Africa).   Water Research
       4:661-672.   1970.

 488.   Nupen, E.  M.,  B.   W.  Bateman, and N. C. McKenny.   The
       Reduction of Virus by  the  Various Unit Processes  Used  in
       the Reclamation of Sewage  to Potable Waters.  In:  Virus
       Survival  in Water and  Wastewater Systems.  MalTna and
       Sagik, eds.   Water Resources Symposium #7.  pp. 107-114.
       1974.

 489.   Ockershausen, R.  W.   Alum  vs.  Phosphates:  It's No Contest.
      Water and Wastes   Engineering.   H:54-61.   November 1974.

 490.  Ockershausen, R.  W.    In-Plant Usage Works  and Works.
      Environmental Science and  Technology.   865:420-423   May
      1974.

491.  O'Connor,  J. T.  Removal  of Trace Inorganic Constituents
      by Conventional Water Treatment Processes.  In:   Proceed-
      ings,  16th Water  Quality  Conference, University of Illinois
      at Urbana-Champaign.   1974.  pp.  99-110.

492.  O'Farrell, T. P.,  et.al.   Nitrogen  Removal by Ammonia
      Stripping.    JWPCF.   W(8):1527-1535.   August 1972.

493<  ^orf'  h/Shsflii-   Chloride and Lead In Urban Snow.
      JWPCF. £6(4):766-771.  April  1974.
                              324

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494.   Olson, L.  L.  and C.  D.  Binning.   Interactions of Aqueous
      Chlorine with Activated Carbon.   In:  Chemistry of Water
      Supply, Treatment, and  Distribution.  A. J.  Rubin, ed.
      Ann Arbor Science Publishers, Ann Arbor, Michigan.  pp.
      253-295.  1975.

495.   0' Shaughnessy, J. C., ejt aj_.  Soluble Phosphorus Removal
      in the Activated Sludge Process.  Part  II:  Sludge
      Digestion Study.  Water Quality Office, EPA.  October  1971.

496.   Ottoboni, A.  and A.  E.  Greenberg.  lexicological Aspects
      of Wastewater Reclamation - A Preliminary Report.  JWPCF.
      42_(4) :493-499.  April 1970.

497.   Owens, L. B.  and D.  W.  Nelson.  Relationship of Various
      Indices of Water Quality to Denitrif icat ,on  in  Surface
      Waters.  NTIS/PB-237 702/6WP.   1972.

498.   Oza,  P. P. and M. Chaudhuri.  Removal of  Viruses  from
      Water  by Sorption on Coal.  Water Research.  £:707-712.
      1975.

499.   Palin,  A. T.   Chemistry of  Modern Chlorination.   Water
      Services.  _7Jk7-12,  53-56.  January 1974.

500.   Parhad, N. M. and N. U. Rao.  Effect  of pH  on  Survival of
      Escherichia  coli.   JWPCF.   46.(5) : 980-986.   May  1974.

501.   Paris,  D. F. , £t  aJL   Microbial  Degradation  and Accumula-
      tion  of Pesticides  in  Aquatic Systems.   EPA-660/3-75-Op7.
      March 1975.

502.  Park,  J. W.   An  Evaluation  of Three Combined Sewer Over-
      flow  Treatment  Alternatives.  EPA-670/2-74-079.   December
      1974.

503.  Parker,  C. D.   Microbiological  Aspects  of Lagoon  Treatment,
      JWPCF.   3_4.(2): 149-1 61.   February 1962.

504.  Parkhurst, J. D.  Virus  Study:   Supplement  to tiie Project
      Report for Facilities  Planning  Study.  Los  Angeles County
      Sanitation District.   November  1974.

505.  Parkhurst, J. D. , et. aJL   Demi neral ization  of Wastewater
      by Ion Exchange.  Advances in Water Pollution Research.
 506.   Patterson,  J.  W.   Wastewater Treatment Technology.  Ann
       Arbor Science  Publishers, Ann Arbor, Michigan.  1975.
                                325

-------
507.  Patterson, J.  W. , P. Shimada, and C. N. Haas.  Heavy
      Metals Transport Through Municipal Sewage Treatment
      Plants.  Second National Conference on Complete Water
      Reuse.  Chicago.  1975.

508.  Pavoni, J. L.  and M. E. Tittlebaum.  Virus Inactivation
      in Secondary Wastewater Treatment Plant Effluent Using
      Ozone.  In:  Virus Survival in Water and Wastewater
      Systems.  Malina & Sagik, eds.  Water Resources Symposium
      #7.   pp. 180-198.  1974.

509.  Pavoni, J. L., ejt ^1_.  Virus Removal from Wastewater Using
      Ozone.  Water  and Sewage Works.  IJjK 12):59-67.  December
      1972.

510.  Pearson, F. and T. G. Metcalf.  The Use of Magnetic Iron
      Oxide for Recovery of Virus from Water.  NTIS/PB-234 626/
      OWP.   1974.

511.  Pennypacker, S. P., W.  E. Sopper, and L. F.  Kardos.  Reno-
      vation of Wastewater Effluent by Irrigation  of Forest Land
      JWPCF.  3£(2):285-296.   February 1967.

512.  Perhac, R. M.   Distribution of Cd, Co, Cu, Fe, Mn, Ni, Pb
      and  Zn in Dissolved and Particulate Solids from Two
      Streams in Tennessee.  Journal of Hydrology.  1_5:177-186.
      1972.

513.  Perry, R.   Mercury Recovery from Contaminated Waste Water
      and  Sludges.  EPA-660/2-74-086.  December 1974.

514.  Pfeiffer,  K. R.  The Homestead Typhoid Outbreak.  JAWWA.
      ££(12):803-805.  December 1973.

515.  Phillips,  J. D. and G.  L. Shell.  Pilot Plant Studies of
      Effluent Reclamation.  Water and Wastes Engineering.
      6.(11 ):38-41.  November 1969.

516.  Phillips,  W. J.  II.  The Direct Reuse of Reclaimed
      Wastewater:  Pros, Cons, and Alternatives.   JAWWA.  66(4);
      231-237.  April 1974.

517.  Physical-Chemical Nitrogen Removal:  Wastewater Treatment.
      EPA  Technology Transfer.  July 1974.

518.  Physical-Chemical Wastewater Treatment Plant Design.  EPA
      Technology Transfer.  August 1973.

519.  Pillay, K. K.  S., et. aj_.  Mercury Pollution  of Lake Erie
      Ecosphere.  Environmental Research.  5^:172-181.  May 1972.
                              326

-------
520.  Pitt, W. W., R. L. Jolley, and S. Katz.  Automated
      Analysis of Individual Refractory Organics in Polluted
      Water.  EPA/660/2-74-076.  August 1974.

521.  Pittwell, L. R.  Metals Coordinated by Ligands Normally
      Found in Natural Waters.  Journal of Hydrology.  21:301-
      304 .   1 974 .                                       — '

522.  Pokornts, Y. and K. Kulikova.  Effects of Pesticides on
      Reservoir Water.  Pesticide Abstracts.  74-1874.  1974.

523.  Poon, C. P.  C.   Studies on the Instantaneous Death of
      Airborne Escherichia coli .  American Journal of Epidemi-
      ology.  £4(1): 1-19.  July 1966.

524.  Popalisky, J.  R. and F. W. Pogge.  Detecting and Treating
      Organic  Taste-&-Order  (!) Compounds in the Missouri
      River.  JAWWA.   64_(8) : 505-51 1 .  August 1972.

525.  Posselt, H.  S.  and W. J. Weber, Jr.  Removal of Cadmium
      from Waters  and Wastes by Sorption on Hydrous Metal Oxides
      for Water Treatment.  JJK  Chemistry of Water Supply
      Treatment, and  Distribution.  A.  J. Rubin, ed.  Ann Arbor
      Science  Publishers, Ann Arbor, Michigan,  pp. 89-108.
      I y / D •

526.  Pound, C. E. and R. W. Crites.  Characteristics of
      Municipal Effluents.  J_n:  Recycling Municipal Sludges
      and Effluents  on Land; Proceedings of the Joint Conference
      July 9-13, 1973.  pp. 49-61 .

527.  Prakasam,» T. B. S. and R. C. Loehr.  Microbial Nitrifica-
      tion and Denitrif ication in Concentrated Wastes   Water
      Research.  6^:859-869.  July 1972.

528.  Prasad,  D. and  P.  H. Jones.  Degradation of Organic
      Nitrogenous  Compounds by Psychrophi 1 ic Bacteria   JWPCF
          ) = 1686- 1691.  July
529.   Preliminary Investigation of Effects on the Environment
      of Boron, Indium Nickel, Selenium, Tin, Vanadium, and
      Their Compounds.  Vol. IV:  Selenium.  EPA-560/2-75-005D
      August 1975.

530.   Premi, P. R.  and A. H. Cornfield.  Incubation Study of
      Nitrogen Mineralization of Soil Treated with Dried
      Sewage Sludge.   Environmental Pollution.  2_(l):l-5.  July
      I *7 / I •

531.   Pressley, T.  A., D. F. Bishop, and S. G. Roan.  Ammonia-
      Nitrogen Removal by Breakpoint Chlori nation .  Environmental
      Science and Technology.  6/7) : 622-626.  July 1972.


                               327

-------
532.   Preul,  H.  C.   Underground  Movement  of  Nitrogen.   Advances
       in Water  Pollution  Research.   1966(1):309-328.

533.   Process Design  Manual  for  Nitrogen  Control.   EPA  Technology
       Transfer.  October  1975.

534.   Radding,  S. B. , e_t  a_l_.   Review  of the  Environmental  Fate
       of Selected Chemicals.   EPA-560/5-75-001.   January  1975.

535.   Ragone, S. E. ,  J. Vecchioli, and H.  F.  H.  Ku.   Short-term
       Effect  of  Injection of Tertiary Treated  Sewage  on  Iron
       Concentration  of Water in  Magothy Aquifer,  Bay  Park,  New
       York.   In:  Reprints of  Paper  Presented  at  the  Inter-
       nationalSymposium  on  Underground Waste  Management  and
       Artificial Recharge.   J. Braustein,  ed.   G.  Banta,
       Menasha,  Wise.  1:273-290.  1973.

536.   Rains,  B.  A.,  M. J. DePrimo and T.  L.  Groseclose.   Odors
       Emitted from  Raw and Digested  Sewage Sludge.  EPA-670/2-
       73-098.   December 1973.

537.   Ralph Stone and Company.   Treatment  Effectiveness  for the
       Removal of Selected Contaminants from  Drinking  Water;
       Final Report.    Water Supply Division,  EPA.   March  1975.

538.   Recycling  Sludge and Sewage Effluent by  Land  Disposal.
       Environmental  Science and  Technology.   6_( 10) :871-873.
       October 1972.

539.   Reeves, T. G.    Nitrogen  Removal:  A  Literature  Review.
       JWPCF.  44(10):1895-1908.  October  1972.

540.   Reid, G. W. ,  et_ a_l_.  Effects of Metallic  Ions on  Biolog-
       ical  Waste Treatment Processes.  Water  and  Sewage  Works.
      j_I_5(7):320-325.  July  1968.

541.   Research Foundation to Undertake Study  on Organics
       Removal.  Watercare.  San  Jose, Ca.  September  1975.

542.   Richardson, E.  W.,  E.  D. Stobbe, and B.  Bernstein.   Ion
       Exchange Traps  Chromates for Reuse.  Environmental  Science
       and Technology.  2_( 11): 1 006-1 01 6.

543.   Rickert, D. A.  and  J.  V. Hunter.  Effects of  Aeration
      Time on Soluble Organics during Activated Sludge  Treatment.
       JWPCF.  43_(9):134-138.   January 1971.

544.   Rizzo, J.   L.  and R. E. Schade.  Secondary Treatment with
       Granular Activated  Carbon.  Water and Sewage  Works.   116
       (8):307-312.   August 1969.                           	
                              328

-------
545.   Roan,  S.  G. ,  D.  F.  Bishop,  and T.  A.  Pressley.   Laboratory
      Ozonation of  Municipal  Wastewaters.   EPA-670/2-73-075.
      September 1973.

546.   Robeck,  6.  G.,  e_t al.   Effectiveness  of Water Treatment
      Processes in  PestiFTde  Removal.   JAWWA.  57J2): 181 -199.
      February 1965.

547.   Robeck,  G.  G.,  N. H.  Clarke,  and K.  A.  Postal.   Effective-
      ness of  Water Treatment Processes  in  Virus Removal.
      JAWWA.   54(10):1275-1292.   October 1962.

548.   Robinson, C.  N., Jr.   Polyelectrolytes  as Primary Coagu-
      lants  for Potable-Water Systems.  JAWWA.   66(4) :252-257.
      April  1974.                                —

549.   Roersma, R.  E.,  G.  J.  Alsema, and I.  H. Anthonissen.
      Removal  of Hexavalent Chromium by Activated Carbon.
      Chemical Abstracts.  83_:65112w.   1975.

550.   Rogers,  C.  J.  and R.  L. Landreth.   Degradation Mechanisms:
      Controlling the Bioaccumulation of Hazardous Materials.
      EPA-670/2-75-005.  January 1975.

551.   Rohm and Haas.   Summary Bulletin:   Amberlite Polymeric
      Adsorbents.   Philadelphia, Pa.  February 1975.

552.   The Role of Soils and Sediments in Reducing the Concentra-
      tion of  Heavy Metals, Fluorides, and Pesticides in
      Percolating Waste Discharges (Memorandum Report).   State
      of California Resources Agency, Department of Water
      Resources.  June 1972.

553.   Romero,  J. C.   The Movement of Bacteria and Viruses through
      Porous Media.  Ground Water. . 8_(2) :34-48.  March-April  1970.

554.   Rook,  J. J.  Formation of Haloforms during Chlorination
      of Natural Waters.  Water Treatment and Examination.
      23_:234.   1974.

555.   Rook,  J. J.  Haloforms in Drinking Water.  JAWWA.   68(3):
      168-172.  March  1976.                               ~

556.   Rosen, H. M.   Use of Ozone and Oxygen  in Advanced Waste-
      water Treatment.  JWPCF.  45(12) :2521-2536.  December
      1973.

557.   Rosen, H. M., F. E. Lowther, and  R. G. Clark.  Economical
      Wastewater Disinfection with Ozone.  In:   Johnson,  J.  D.
      Disinfection - Water and Wastewater. ~A~nn  Arbor  Science
      Publishers, Ann  Arbor, Mich.  pp. 233-248.   1975.
                               329

-------
558.  Routh, J. D.  DDT Residues  in Salinas River Sediments.
      Bulletin of Environmental Contamination and Toxicology.
      7.(2/3):168-176.  February/March 1972.

559.  Rozell, R. B. and H. A. Swain, Jr.   Removal of Manganese
      from Mine Drainage by Ozone and Chlorine.  EPA-670/2-75-
      006.  March 1975.

560.  Rubenstein, S. H., et al.   Viruses in Metropolitan Waters:
      Concentration by PoTy"eTectrolytes, Freeze Concentration,
      and Ultrafiltration.  JAWWA.  £5_(3): 200-202.  March 1973.

561.  Rubin, A. J. and G.  P. Hanna.  Coagulation of Bacterium
      Escherichia coli by Aluminum Nitrate.  Environmental
      Science and Technology.  2.(5) :358-362.  May 1968.

562.  Rudolfs, W., L. L.  Folk, and R. A. Rogotzkie.  Contamina-
      tion of Vegetables Grown in Polluted Soil.  Part V:
      Helminthic Decontamination.  Sewage  and Industrial Wastes.
      2^3:853-860.  1951.

563.  Salmonella Surveillance.  U.S. Center for Disease Control,
      HEW.  Report No.  122.   February 1975.

564.  Scarpino, P. V.,  e± a_l_.  Effectiveness of Hypochlorous
      Acid and Hypochlorite Ion in Destruction of Viruses and
      Bacteria.  In;  Chemistry of Water Supply, Treatment and
      Distribution.  A. J. Rubin, ed.  Ann Arbor Science
      Publishers, Ann Arbor, Michigan,   pp. 359-368.   1975.

565.  Schaub, S. A., j^t a_K   Land Application of Wastewater:
      The Fate of Viruses, Bacteria, and Heavy Metals  at a
      Rapid Infiltration Site.  NTIS/AD-A011263.  May  1975.

566.  Schistosomiasis Control:  Report of  a WHO Expert Committee,
      Geneva.  July 3-7,  1972.

567.  Schmid, L. A.  and R. E. McKinney.  Phosphate Removal by a
      Lime-Biological Treatment Scheme.  JWPCF.  41(7):1259-
      1276.   July 1969.

568.  Schmidt, C. J. and E.  V. Clements  III.  Reuse of Municipal
      Wastewater for Groundwater  Recharge.  EPA-68-03-2140.
      1975.

569.  Schmidt, C. J., I.  Kugelman, and E.  V. Clements  III.
      Municipal Wastewater Reuse  in the  U.S.  JWPCF.   47(9):
      2229-2245.  September 1975.

570.  Schwartz, H.  G.,  Jr.  Adsorption of  Selected Pesticides
      on Activated Carbon and Mineral Surfaces.  Environmental
      Science and Technology.  1(4):332-337.  April 1967.

                              330

-------
571.   Selleck,  R.  E., L.  W.  Bracewell,  and R. Carter.  The
      Significance and Control of Wastewater Floatables in
      Coastal  Waters.  EPA/660-3-74-016.  January 1974.

572.   Sepp, E.   Nitrogen Cycle in Ground Water.  Bureau of
      Sanitary Engineering,  State of California.  1970.

573.   Seppalainen, A. M.  and I. Hakkinen.  Electrophysiological
      Findings  in  Diphenyl  Poisoning.  Journal of Neurology,
      Neurosurgery, and Psychiatry.   38^(3)-.248-252.   1975.

574.   Shane, M. S., S. B. Wilson, and C. R.  Fries.   Virus-Host
      System for Use in the  Study of Virus Removal.   JAWWA.
      7jf(9):1184-1186.  September 1967.

575.   Shelton,  S.  P. and W.  A. Drewry.   Tests of Coagulants
      for the Reduction of Viruses,  Turbidity, and Chemical
      Oxygen Demand.  JAWWA.  6J5(10) :627-635.  October 1973.

576.   Shen, Y.  S.   Study of Arsenic  Removal  from Drinking Water.
      JAWWA.  6_5(8):543-548.  August 1973.

577.   Shen, Y.  S.  and C. S.  Shen.  Relation Between  Blackfoot
      Disease and the Pollution of Drinking Water by Arsenic  in
      Taiwan.  JWPCF.  3_6(3):281.  March  1964.

578.   Shields, C.  P.  Reverse Osmosis for Municipal  Water  Supply.
      Water and Sewage Works.  119(1) -.61-70.   January  1972.

579.   Shigella Surveillance.  U.S. Center for  Disease  Control,
      HEW.  1974.

580.  Shigella Surveillance Annual Summary.   U.S. Center  for
      Disease  Control, HEW.   Report  No.  38.   September 1976.

581.  Shimizu, Y.,  et  al.   Further Studies  of the  Interaction
      of  Chlorine  andf I57ganic  Molecules in  Water.   OWRR:   B-057-
      RI.   Office  of Water  Research  and Technology,  U.S.  Depart-
      ment  of  the  Interior.

582.  Shuckrow, A.  J.,  et al.   Treatment of Raw and  Combined
      Sewage.  Water an^TSewage  Works.   1J_8(4): 104-111.   April
      1971.

583.  Shuval,  H.  I.   Health Factors  in  the  Re-Use  of Waste
      Water for Agricultural, Industrial, and Municipal  Purposes
       In:   Problems in Community Wastes Management.   World
      Health  Organization,   pp.  76-89.   1969.

584.  Shuval,  H.  I., et al.   Chlorlnation of Wastewater for
      Virus Control. "RunTch Abstracts  - Section II.  38(3):343.
                               331

-------
585.  Shuval , H. I., e_t aj_.  The  Inactivation of  Enteroviruses
      in Sewage by Chlorination.  Advances  in Water  Pollution
      Research.  1966(2):37-51.

586.  Shuval, H. I., E. Katzenelson, and  I. Butum.   Risk  of
      Communicable Disease  Infection Associated with Wastewater
      Irrigation in Agricultural  Settlements.  Science.   194:
      944-946.  November 26, 1976.

587.  Sierka, R. A.   Activated Carbon Treatment and  Ozonation
      of MUST Hospital Composite  and Individual Component Waste-
      waters and MUST Laundry Composite Wastewaters.  NTIS/AS-
      A008 347/7WR.   May 1975.

588.  Sigworth, E.  A.  and S. B. Smith.  Adsorption of Inorganic
      Compounds by Activated Carbon.  JAWWA.  64(6):386-391.
      June 1972.                              ~~~

589.  Simpson, R.  M.   The Separation of Organic Ctiemicals from
      Water.  Presented at the 3rd Symposium of the  Institute
      of Advanced  Sanitation Research, International.  April 13,
      1972.

590.  Singer,  P. C.   Anaerobic Control of Phosphate  by Ferrous
      Iron.  JWPCF.   £4(4):663-669.   April  1972.

591.  Singer,..F. C.   Trace Metals and Metal-Organic  Interactions
      in Natural Waters.   Ann Arbor Science Publishers, Ann
      Arbor, Michigan.   1974.

592.  Slanetz, L.  W.,  et al.  Survival of Enteric Bacteria and
      Viruses  in OxidatTon Pond Systems.   University of New
      Hampshire.  197?.

593.  Smith, J.  M.,  A.  N.  Masse, and R.  P. Miele.  Renovation
      of Municipal  Wastewater by Reverse Osmosis.  Water
      Pollution Control  Research Series 17040 - 05/70.  May 1970,

594.  Smith, J.  M. ,  e_t al.   Nitrogen Removal from Municipal
      Waste Water  by  CoTumnar Denitrification.  Environmental
      Science  and  Technology.  6>(3): 260-267.  March  1972.

595.  Smith, R.  J.,  ejt aJL   Relationships of Indicator and
      Pathogenic Bacteria  in Stream Waters.  JWPCF.  45(8) :1736-
      1745.  August  1973.

596.  Snoeyink,  V.  L.  and  F. I. Markus.   Chlorine Residuals in
      Treated  Effluents.   NTIS/PB-227-268.  August 1975.

597.  Snoeyink,  V.  L.  and  F. I. Markus.   Chlorine Residuals in
      Treated  Effluents.   Water and Sewage Works.  121(4);35-38.
      April 1974.                                         ^


                               332

-------
598.  Snoeyink, V. L., e_t^ aj_.  Active Carbon:  Dechlorination
      and the Adsorption of Organic Compounds.  J_n:  Chemistry
      of Water Supply, Treatment, and Distribution.  A. J.
      Rubin, ed.  Ann Arbor Science Publishers, Ann Arbor, Mich
      pp. 233-252.  1975,

599.  Snoeyink, V. L., W". J. Weber, and H. B. Mark.  Sorption of
      Phenol and Nitrophenol by Activated Carbon.  Environmental
      Science and Technology.  8^:918-926.  October 1969.

600.  Sobsey, M. D.  Enteric Viruses and Drinking-Water
      Supplies.  JAWWA.  67J8): 41 4-418.  August 1975.

601.  Sobsey, M. D. , £t aj_.  Virus Removal and Inactivation by
      Physical-Chemical Waste Treatment.  Journal of the
      Environmental Engineering  Division, ASCE.  99(EE3):245-
      252.   June 1973.

602.  Sorber, C. A., S. A.  Schaub, and H. T. Bausum.  An Assess-
      ment of a Potential Virus  Hazard Associated with Spray
      Irrigation of Domestic Wastewaters.  Virus Survival in
      Water and Wastewater Systems.  Malina and Sagik, eds.
      Water Resources Symposium  #7.  pp. 241-352.  1974.

603.  Sorber, C. A., H. T.  Bausum, and S. A. Schaub.  Bacterial
      Aerosols  Created by Spray  Irrigation of Wastewater.
      Presented at the 1975 Sprinkler Irrigation Association
      Technical Conference, Atlanta, Georgia.  February 1975.

604.  Sorber, C. A., S. A.  Schaub, and K. M. Guter.  Problem
      Definition Study:  Evaluation of Health and Hygiene
      Aspects of Land Disposal of Wastewater at Military Instal-
      lations.   Army Medical Environmental Engineering Research
      Unit.   August 1972.

605.  Spear, R. C., D. L. Jenkins, and T. H. Milby.  Pesticide
      Residues  and Field Workers.  Environmental Science and
      Technology.  £(4):308-313.   April 1975.

606.  Spody, B. and S. D. Adams.   Improved Activated Sludge
      Treatment with Carbon.  Deeds and Data.  January 1976.

607.  Spohr, G. and A. Talts.  Phosphate Removal by pH Controlled
      Lime Dosage.  Public Works.  l_gi_:63-66.  July 1966.

608.  Sproul, 0. J.  Virus  Inactivation by Water Treatment.
      JAWWA.  64(l):31-35.  January 1972.

609.  Sproul, 0. J. , ejt aj_.  Virus Removal by  Adsorption  in
      Waste Water Treatment Process.  Advances in Water  Pollu-
      tion Research.   1969:541-554.
                               333

-------
610.  Stander, G. J. and J. W. Funke.  Direct Cycle Water Reuse
      Provides Drinking Water Supply in South Africa.  Water and
      Wastes Engineering.  6j5):66-67.  May 1969.

611.  Stander, G. J. and L. R. J. Van Vuuren.  The Reclamation
      of Potable Water from Wastewater.  JWPCF.  £L(3):355-365.
      March 1969.

612.  Stanford, G. B. and R. Tuburan.  Morbidity Risk  Factors
      from Spray Irrigation with Treated Wastewaters.  In:
      Wastewater Use in the Production of Food and Fiber  -
      Proceedings.  EPA-660/2-74-041 , pp. 56-64.  June 1974.

613.  Starkey, R. J., Jr., ejt aj_.  An Investigation of Ion
      Removal from Water and Wastewater.  EPA/660/3-74-022.
      August 1973.

614.  Stasiuk, W. N., Jr., L.  J. Hitling, and W. W. Shuster.
      Nitrogen Removal by Catalyst-aided Breakpoint Chiorination,
      JWPCF.   4£(8):1974-1983.  August 1974.

615.  "State of the Art" Review of Health Aspects of Wastewater
      Reclamation for Groundwater Recharge.  State of  California
      Water Resources Control  Board.  November 1975.

616.  Stevens, A. A., ejt aJL  Chlorination of Organics in
      Drinking Water.  JAWWA.   6^(11 ): 615-619.  November  1976.

617.  Stobbe, H., ejt. a_l_.  Fundamental Remarks on the Problem
      of Occupationally Caused Leukemias.  Pesticide Abstracts.
      75-0812.  1975.

618.  Stone,  R. and H. Smallwood.  Intermedia Aspects  of  Air
      and Water Pollution Control.   EPA-660/5-73-003.  1973.

619.  Stoveken, J.  and T. Sproston.  Ozone and Chlorine
      Degradation of Wastewater Pollutants.  NTIS/PB-238  365/1WP,
      June 1974.

620.  Stover, E.  L. and D. F.  Kincannon.  One- Versus  Two-Stage
      Nitrification in the Activated Sludge Process.   JWPCF.
      4J3(4):645-651.  April 1976.

621.  Stringer, R.  and C. W. Kruse.  Amoebic Cysticidal
      Properties  of Halogens in Water.  Journal of the Sanitary
      Engineering Division, ASCE.  9_7(SA6) :801-811 .  December
      1971.

622.  Stukenberg, J. R.  Biological-Chemical Wastewater Treat-
      ment.  JWPCF.  43.(9):1791-1806.  September 1971.
                               334

-------
623.   Stukenberg, 0.  R.   Physical-Chemical Wastewater Treatment
      Using a Coagulation-Adsorption Process.  JWPCF.  47(2):
      338-353.   February 1975.

624.   Stumm, W.  and J.  0. Morgan.  Aquatic Chemistry:  An
      Introduction Emphasizing Chemical Equilibria in Natural
      Waters.  Wi1ey-Interscience, New York.  1970.

625.   Sturm, M.  and N.  N. Hatch.  The Sarasota Phosphate Removal
      Project.   Water and Sewage Works.  121(3) -.39-40, 42-43,
      59.  March 1974.

626.   Sunshine,  I.  Handbook of Analytical Toxicology.  Chemical
      Rubber Company, Cleveland, Ohio.  1969.

627.   Susag, R.  H.  BOD  Reduction by Chiorination.   JWPCF.
      4ip_(ll):R434-R444.   November 1968.

628.   Sutton, P. M., et  a!.   Efficacy of Biological  Nitrifica-
      tion.  Water PoTTution  Control Federation.   47th Annual
      Conference.  Denver, Colorado.  October 1974.

629.   Sutton, P. M., e_t  aj_.   Low-Temperature Biological  Denitri-
      fication of Wastewater.   JWPCF.  47(1):122-134.  January
      1975.

630.   Sutton, P. M., K.  L. Murphy,  and B.  E. Jank.   Nitrogen
      Control:  A Basis  for  Design  with Activated  Sludge  Systems
      Conference  on Nitrogen  as  a Water Pollutant.   Copenhagen,
      Denmark.  August  1975.

631.   Swanson, C. L., e_^ a_l_.   Mercury  Removal  from Waste  Water
      with  Starch Zanthate-Cationic  Polymer  Complex.  Environ-
      mental Science and Technology.  _7_:614-619.   July  1973.

632.   Symons, J.  M. , e_t  aj_.   National  Organics  Reconnaissance
      Survey for  Halogenated  Organics.  JAWWA.   4_7_(11): 634-648.
      November  1975.

633.   Talbot, P.  and R.  H. Harris.   The  Implications of  Cancer-
      Causing Substances in  Mississippi  River  Water.  Environ-
      mental Defense Fund, Washington,  D.C.   November 1974.

634.   Tamura, 0.,  e± aj_.  Relationship  Between  Consumption of
      Pesticides  and Chronological  Changes in  Myopia in  School
      Children  in Tokushima  Prefecture.   Pesticides Abstracts.
      75-1893.   1975.

635.  Tank,  N.  H.   Relationship Between  BOD Removal and LAS
      Detergent  Removal.  NTIS/PB-232 997/7WP.   May 1974.
                                335

-------
636.  Tardiff, R. G. and M.  Deinzer.  Toxicity  of  Organic
      Compounds  in  Drinking  Water.  Proceedings  of 15th  Water
      Quality Conference,  Champaign,  Illinois,   pp.  23-32.
      February 1973.

637.  Taylor, F. B.  Viruses - What is Their Significance  in
      Water Supplies?  JAWWA.  66(5):306-311.   May 1974.

638.  Tchobanoglous, G.  Filtration Techniques  in  Tertiary
      Treatment.  JWPCF.   4_2(4): 604-623.  April  1970.

639.  Thayer, S. E. and 0. J. Sproul.   Virus Inactivation  in
      Water-Softening Precipitation Processes.   JAWWA.   58(8):
      1063-10M.  August 1966.

640.  Thiem, L.  T.   Removal  of Mercury from  Drinking Water Using
      Powdered Activated Carbon.  In:   Proceedings,  96th Annual
      Conference American  Water Works Conference.   June  20-25,
      1976.  pp. 17-3.

641.  Thiem, L.  T.   Removal  of Mercury from  Drinking Water Using
      Powdered Activated Carbon.  Water and  Sewage Works.  123
      (8):71.   August 1976.

642.  Thimann, K. V.  Herbicides in Vietnam.  Science.   185
      (4147):207.  July 19,  1974.

643.  Thorup,  R.  T.  , e_t a_l_.  Virus Removal  by Coagulation  with
      Polyelectrolytes.  JAWWA.  61(2):97-101.   February 1970.

644.  Three Summary Tables Relating to Metals Removal.   Dallas
      Water Utilities Water  Reclamation Research Center.
      Dallas,  Texas.  September 1975.

645.  Tinsley, T. and J. L.  Melnick.  Potential  Ecological
      Hazards  of Pesticide Viruses.   Intervirology.  2^(3):206-
      208.  1973/74.

646.  Tofflemire, T. J. and  G. P. Brizner.   Deep-Well  Injection
      of Wastewater.  JWPCF.  43^(7): 1468-1479.   July 1971.

647.  Tofflemire, T. J., e_t  a_K  Activated  Carbon  Adsorption
      and Polishing of Strong Wastewater.   JWPCF.   45(10):2166-
      2179.  October 1973.

648.  Tornabene, T.  G. and H. W. Edwards.   Microbial Uptake of
      Lead.  Science.  VTjSj 1334-1335.   June  1972.

649.  Tossey,  D., e_t aj_.   Tertiary Treatment by  Flocculation and
      Filtration.  Journal  of the Sanitary  Engineering Division,
      ASCE.  i6(SAl):75-90.  February 1970.
                              336

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650.   Tromp,  S.  W.   Possible  Effects  of  Geophysical  and  Geo-
      chemical  Factors  on Development and  Geographic Distribution
      of Cancer.   Schweizerische Zeitschrift fur Allgemeine
      Pathologic und Bakteriologie.   1_8(5):929-939.   1955.

651.   Ulmgren,  L.   Swedish Experiences in  Chemical  Treatment of
      Wastewater.   JWPCF.  47^(4)-.696-703.   April 1975.

652.   UOP Fluid Systems Division.   Reverse Osmosis.   San Diego,
      California.   1977.

653.   Upgrading Existing Wastewater Treatment Plants:  Case-
      Histories.  EPA Technology Transfer.  August 1973.

654.   Upgrading Lagoons.   EPA Technology Transfer.  August  1973.

655.   Vacker, R. , C. H. Connell, and W.  N. Walls.  Phosphate
      Removal through Municipal Wastewater Treatment at San
      Antonio, Texas.  JWPCF.   3J9(5) :750-771.   May 1967.

656.   Vajdic, A. H.  Gamma Rays vs the  E_._ col i  Monster.  Water
      and Wastes Engineering.   l_2_:29-32.  July  1975.

657.   Vale, J. A. and G. W. Scott.   Organophosphorus Poisoning.
      Guy's Hospital Reports.   1_23J13): 13-25.   1974.

658.   Van Bladel, R. and A. Moreale.  Adsorption  of  Fenuron and
      Monuron  (Substantial Ureas) by  Two  Montmori11onite Clays.
      Soil Science  Proceedings.  38^244-249.  March  1974.

659.  Varma, M. W.,  B. A.  Christian,  and  D.  W.  McKinstry.
      Inactivation  of Sabin Oral Poliomyelitis  Type  I Virus.
      JWPCF.   46^(5): 987-992.   May 1974.

660.  Venosa,  A. D.  Ozone as  a Water and Wastewater Disinfec-
      tant:  A  Literature  Review.   In:  Ozone in  Water  and
      Wastewater Treatment.  Ann ArEoV  Science  Publishers, Ann
      Arbor, Michigan.   pp. 83-100.   1972.

661.  Venosa,  A. D.  and  C. W.  Chambers.   Bactericidal  Effect of
      Various  Combinations of  Gamma  Radiation and Chloramineon
      Aqueous  Suspensions  of Escherichla  coli.   Applied Micro-
      biology.   25^735-744.  May  1973.

662.  Versteeg,  J.  P.  J.  and K. W.  Jager.   Long-Term Occupational
      Exposure to  the  Insecticides  Aldrin,  Dieldrin, Endrin, and
      Telodrin.  British Journal  of Industrial  Medicine.   30(2):
      201-202.   1973.                                      ~

663.  Viets,  F.  G., Jr.  and  R.  H.  Hageman.   Factors Affecting
      the Accumulation  of Nitrate  1n Soil,  Water, and  Plants.
      Agricultural  Handbook  No. 413.  U.S.  Department  of Agri-
      culture, Washington, D.C.  November 1971.

                                337

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664.  Viruses in Water.  JAWWA.  61_(10):491-494.  October 1969.

665.  Voelkel, K. G., D. W. Martin, and R. W. Deering.  Joint
      Treatment of Municipal and Pulp Mill Effluents.  JWPCF.
      4_i6(4):634-656.  April 1974.

666.  Wachinski, A.  M., V.  D.  Adams, and J. H. Reynolds.
      Biological Treatment of the Phenoxy Herbicides 2,4-D and
      2,4,5-T in a Closed System.  Utah Water Research Laboratory,
      Utah State University.  March 1974.

667.  Wallace, R. N. and D. E. Burns.   Factors Affecting Powdered
      Carbon Treatment of a Municipal  Wastewater.  JWPCF.  48
      (3):511-519.  March 1976.

668.  Waller, D. H.   Pollution from Combined Sewer Overflows.
      Proceedings of the Conference on Pollution.  St. Mary's
      University, Halifax.   pp. 67-80.  August 1969.

669.  Ward, P. S.  Carcinogens Complicate Chlorine Question.
      JWPCF.  <4_6( 12).-2638-2640.  December 1974.

670.  Wastewater Filtration:  Design Considerations.  EPA
      Technology Transfer.   July 1974.

671.  Water Purification Associates.  Innovative Technology
      Study Prepared for the National  Commission on Water
      Quality.  August 1975.

672.  Water Quality Criteria 1972.  U.S. Environmental Protection
      Agency, 1972.

673.  Watkins, S. H.  Coliform Bacteria Growth and Control in
      Aerated Stabilization Basins.  EPA-660/2-73-028.
      December 1973.

674.  Weber, W.  J. and J. C. Morris.  Equilibria and Capacities
      for Adsorption on Carbon.  Journal of the Sanitary
      Engineering Division, ASCE.  9£(SA3):79-107.  June 1964.

675.  Weber, W.  J.,  Jr. and L. H. Ketchum, Jr.  Activated Silica
      in Wastewater Coagulation.  EPA-670/2-74-047.  June 1974.

676.  Weber, W.  J.,  Jr., C. B. Hopkins, and R. Bloom, Jr.
      Physicochemical Treatment of Wastewater.  JWPCF.  42J1):
      83-99.  January 1970.

677.  Wei, I. W. and C. Morris.  Dynamics of Breakout Chlorina-
      tion.  In:  Chemistry of Water Supply, Treatment, and
      Distribution.   A. J.  Rubin, ed.   Ann Arbor Science
      Publishers, Ann Arbor, Michigan.  pp. 297-332.  1975.
                               338

-------
678.   Wei, I. W., R. S. Engelbrecht, and J. H. Austin.  Removal
      of Nematodes by Rapid Sand Filtration.  Journal of the
      Sanitary Engineering Division, ASCE.  S>5_(SA1 ): 1-16.
      February 1969.

679.   Weibel, S. R., e_t a_l_.  Characterization, Treatment, and
      Disposal of Urban Stormwater.  Advances in Water Pollution
      Research.  1966(1):329-352.

680.   Weibel, S. R. , ejt aj_.  Pesticides and Other Contaminants
      in Rainfall, and Runoff.  JAWWA.  58(8): 1075-1084.  August
      1966.                            ~~

681.   Wellings, F. M., A.  L. Lewis, and C.  W. Mountain.  The
      Demonstration of Solids-Associated Virus in Wastewater
      and Sludge.   Epidemiology  Research Center, State of
      Florida Division of  Public Health.

682.   Wellings, F.  M. , e_t  aj_.  Demonstration  of Virus  in Ground-
      water  after Effluent Discharge onto  Soil.  Applied
      Microbiology.  49i(6): 751-757.  June  1975.

683.   Wellings, F.  M., A.  L. Lewis, and C.  W. Mountain.  Pathogen
      Viruses May Thwart Land Disposal.  Water and  Wastes
      Engineering.  l_2:70-74.  March 1975.

684.   Weng,  C. and  A. H. Molof.  Nitrification in  the  Biological
      Fixed-Film Rotating  Disk System.  JWPCF.  46(7) :1674-1685.
      July 1974.

685.   Wesner, G. M. and  D. C. Baier.   Injection of  Reclaimed
      Wastewater into  Confined Aquifers.   JAWWA.   62(3):203-210.
      March  1970.

686.   Westing, A. H.   Ecocide:   Our  Last  Gift to  Indochina.
      Environmental Quality.  4_(5):36-42,  62-65.   May  1973.

687.   White,  G.  C.  Disinfecting Wastewater with  Chlorination/
      Dechlorination.   Part  I.   Water  and  Sewage  Works.   121(8):
      70-71.  August  1974.

688.   White,  G.  C.   Disinfection:   The Last Line  of Defense  for
      Potable Water.   JAWWA.   6J7(8) :410-413.  August 1975.

689.   White,  G.  C.   Disinfection Practices in the  San  Francisco
      Bay  Area.   JWPCF.   46(1):87-101.  January  1974.

690.   Wilhelmi,  A.  R.  and  R.  B.  Ely.   A Two-Step  Process for
      Toxic  Wastewaters.   Chemical  Engineering.   83(4):105-109.
      February  16,  1976.
                               339

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691.   Willenbrink,  R.   Wastewater Reuse and Inplant Treatment.
      AIChE  Symposium  Series.   £9(135):153-154.   1973,

692.   Williams,  L.  G.,  J.  C.  Joyce,  and J.  T.  Monk, Jr.  Stream-
      Velocity Effects  on  the Heavy  Metal Concentrations.
      JAWWA.  64_(4):275-279.   April  1973.

693.   Williams,  T.  C.  and  S.  K. Malhotra.  Phosphorus Removal
      for Aerated Lagoon Effluent.  JWPCF.   4_6(1 2): 2696-2703 .
      December 1974.

694.   Wilson, T.  E. and M. D. R. Riddell.  Nitrogen Removal:
      Where Do We Stand?  Water and Wastes Engineering.  1J_:56-
      61.  October 1974.

695.   Windom, H.  L.  Mercury Distribution  in Estuarine-Nearshore
      Environment.  Journal of the Waterways, Harbors,  and
      Coastal Engineering Division, ASCE.  i9:257-265.   May  1973.

696.   Wing, R. E.  Corn Starch Compound  Recovers  Metals  from
      Water.  Industrial Wastes.  21(l):26-27.  January/February
      1975.                       ~

697.   Wing, R. E., e£ al_.   Heavy  Metal Removal  with Starch
      Xanthate-Cationic Polymer  Complex.   JWPCF.   4_6(8):2043-
      2047.  August 1974.

698.   Wing, R. E., W. M.  Doane,  and C. R.  Russell.   Insoluble
      Starch Xanthate:  Use  in  Heavy Metal Removal.   Journal or
      Applied Polymer Science.   l_9:847-854.   1975.

699.  Wolf, H. W.  Biological  Aspects  of Water.  JAWWA.  63_(3):
      181-188.   March  1971.

700.  Wolf, H. W., et  al_.  Virus  Inactivation  during  Tertiary
      Treatment.   JAWWA.   6^(9):526-553.  September 1974.

701.  Wolf,  H. W., e_t  aj_.  Virus Inactivation  during  Tertiary
      Treatment.   In:   Virus Survival  in Water and Wastewater
      Systems.   MaTTna  and Sagik, eds.   Water Resources Symposium
      #7.   pp.  145-157.   1974.

702.  Wood,  D.  K.  and  G.  Tchobanoglous.   Trace Elements in
      Biological  Waste Treatment.  JWPCF.   4_7(7): 1 933-1 945.
      July  1975.

 703.  Woodward,  W.  W. ,  e_t al.   Acute Diarrhea on an Apache
       Indian Reservation. "American Journal  of Epidemiology.
       9£(4):281-290.   1974.

 704.   Worrell,  C.  L.   Management of Organophosphate Intoxication.
       Southern  Medical Journal.  £8(3):335-339.  March  1975.


                                340

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  705.   York,  D.  W.  and W.  A.  Drewry.  Virus Removal by Chemical
         Coagulation.   JAWWA.   £6:711-716.   December 1974.

  706.   Young,  J.  C. ,  et_ a]_.   Packed-Bed Reactors for Secondary
         Effluent  BOD and  Ammonia  Removal.   JWPCF.  47(1):46-56.
         January 1975.

  707.   Young, R.   A.,  P.  N. Cheremisinoff,  and  S.  M.  Feller.
         Tertiary Treatment:  Advanced Wastewater  Techniques.
         Pollution   Engineering.  7^4):26-33.   April  1975.

  708.   Young, R.   H.  F. and N'. C.  Burbank,  Jr.  Virus Removal  in
        Hawaiian Soils.  JAWWA.  6J5:598-604.  September 1973.

  709.   Yu,  C.  C.  and J. R.  Sanborn.  The Fate of Parathion in  a
        Model  Ecosystem.  Bulletin of Environmental Contamination
        and  Toxicology.  Jj[:543-550.  May 1975.

  710.   Yu,  W.  C.   Selective Removal of Mixed Phosphates by
        Activated  Alumina.   JAWWA.   5_8(2): 239-247.  February 1966.

 711.   Zaloum,  R.  and  K.  L. Murphy.   Reduction  of Oxygen  Demand
        of Treated  Wastewater  by Chlorination.  JWPCF.   46(12):
        2770-2777.   December 1974.

 712.  Zanitsch, R. H.   and J.  M. Morand.  Tertiary  Treatment  of
       Combined Wastewater with Granular Activated  Carbon.
       Water and Wastes Engineering.   ,7:58-60.  September  1970.

 713.   Zellich, J. A.  Toxicity of  Combined Chlorine Residuals  to
       Freshwater   Fish.  JWPCF.  44J2) :212-220.    February  1972.

 714.   Zimansky, G. M.   Removal of Trace Metals  during Conven-
       tional  Water Treatment.   JAWWA.  66(10):606-609.   October
       1974.                             —

 715.   Zitko,  V. and  W.  V.  Carson.   Release  of Heavy Metals from
       Sediments by Nitrilotriacetic Acid (NTA).   Chemosphere.
      I(3):n3-118.  May  1972.

716.  ZoBell,  C.  E.  Carcinogenic  Hydrocarbons  as Marine  Environ-
      mental Pollutants:  A Preliminary Report.   In:  Sources
      and Biodegradation  of Carcinogenic Hydrocarbons.  API/EPA/
      USCG Conference  on  the Prevention and  Control  of  Oil
      Spills.   pp. 441-451.  1971.
                              341    «u* oonrtumtict PRINTING of net: 19?s jto-8»o/32 1.3

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                                 TECHNICAL REPORT DATA
                          (Please read Instructions on the reverse before completing)
 REPORT NO.
                                                         3. RECIPIENT'S ACCESSION-NO.
                           _L
 TITLE AND SUBTITLE

  Contaminants Associated with Direct  and Indirect
  Reuse of Municipal Wastewater
             5. REPORT DATE
                March 1978 issuing date
             6. PERFORMING ORGANIZATION CODE
 AUTHOR(S)
                                                         8. PERFORMING ORGANIZATION REPORT NO.
 PERFORMING ORGANIZATION NAME AND ADDRESS
  SCS Engineers, Inc.
  4014 Long Beach Boulevard
  Long Beach, California  90807
              10. PROGRAM ELEMENT NO.

                 1CC614
              11. CONTRACT/GRANT NO.

                 68-02-2257
2. SPONSORING AGENCY NAME AND ADDRESS
  Health Effects Research  Lab-Cincinnati, OH
  Office of Research  and Development
  U.S. Environmental  Protection Agency
  Cincinnati, Ohio  4^268
              13. TYPE OF REPORT AND PERIOD COVERED
                 Final..  7/1/76 - 12/1/77	
              14. SPONSORING AGENCY CODE

                 EPA/600/10
5. SUPPLEMENTARY NOTES
6. ABSTRACT

       This report  is  an attempt to compile the published quantitative data
  available concerning'the health effects associated with direct and indirect reuse
  of treated municipal wastewater for potable purposes.   The assembled information
  includes data  on  the effectiveness of conventional water and wastewater treatment
  and disposal operations in reducing public health contaminant concentrations,  as
  well as data on the  transport of these contaminants  through the environment back
  to man.  The data have been organized in such a manner that the various pathways
  of pollutants  to  man can be evaluated for relative public health significance
  in order to establish necessary research priorities.

       Wastewater treatment processes evaluated include conventional secondary
  treatment and  tertiary processes.  Wastewater disposal techniques evaluated include
  direct discharge  to  fresh surface waters and  land application.  Water treatment
  processes evaluated  include conventional treatment  (chemical coagulation,  with or
  without filtration,  and disinfection) and advanced water treatment (carbon
  adsorption,  ion exchange, and reverse osmosis).
                               KEY WORDS AND DOCUMENT ANALYSIS
                 DESCRIPTORS
                                             b.IDENTIFIERS/OPEN ENDED TERMS
 Waste  water
 Waste  treatment
 Potable water
 Public health
 Water
18. DISTRIBUTION STATEMENT

   Release to public
   Drinking water
   Waste water reuse
   Water treatment
   Water Supply
 19. SECURITY CLASS (ThisReport)
     Unclassified   	
                                             20. SECURITY CLASS (Thispage)
                                                 Unclassified
                                                                          COSATI Field/Group
   68D
21. NO. OF PAGES
   357
                                                                        22. PRICE
EPA Form 2220-1 (9-73)
342

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