Co
Chemicals Identified In
Human Biological Media,
A Data Base

Third Annual Report
October 1981
                         Volume III Part 2

-------
                                         EPA 560/5-81-008A
                                         ORNL/EIS-163/V3-P2
CHEMICALS IDENTIFIED IN HUMAN BIOLOGICAL MEDIA,
                  A DATA BASE
       Third Annual Report,  October 1981
              Volume III,  Part 2
               Records 3501-5271
                  Compiled by

    M.  Virginia Cone,  Margaret F.  Baldauf,
               and Fay M.  Martin

      Chemical Effects Information Center
          Information Center Complex
             Information Division
         OAK RIDGE NATIONAL LABORATORY
          Oak Ridge,  Tennessee 37830
                  operated by
           UNION CARBIDE CORPORATION
                    for the
             DEPARTMENT OF ENERGY
          Contract No. W-7405-eng-26
 This effort was accomplished under the aegis
   of the Interagency Collaborative Group on
 Environmental Carcinogenesis, National Cancer
   Institute, National Institutes of Health,
     Chairperson,  Dr.  Herman F.  Kraybill.
         Date Published — December 1981
         Cindy Stroup,  Project Officer
         Design and Development Branch
         Exposure Evaluation Division
          Office of Toxic Substances
     U.S. Environmental Protection Agency
            Washington, D.C. 20460

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                                CONTENTS

 Part 1
   Acknowledgments	   v
   Introduction   	 .   ^
   Users'  Guide   	   3
   Abbreviations  for Analytical Methods   	   7
   References  for Data Base	   9
   References  for Physical and Chemical Data	  51
   Appendix A.  Journals Searched  	  55
   Appendix B.  Chemicals in Data Base (1979-1981) by CAS
     Preferred Names 	  59
   Appendix C.  Chemicals (1981) by CAS Registry Numbers and
     Preferred Names 	  83
   Appendix D.  Cross-Referenced Chemical Lists  	 103
     1.  CAS Preferred Names — Common Names	105
     2.  Common Names — CAS Preferred Names  	 141
  Appendix E.  Tissues and Body Fluids in Data Base
     (1979-1981)	325
   Indices	329
    Author  	
  Corporate Author
  Tissue
  Keyword ............................  367
Directory of Chemicals (1981) ..................  377
  CAS Pref
  Formulas
    CAS Preferred Names ......................  379
                                                                    090
Part 2
  Data Base
    Nondrugs  ...........................    -,
    Drugs .....................  ........  345
                                  iii

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NONDRUGS

-------
Icctaldehyde
75-C7-0
CS-M-0
!« M.05. IP -123.5 C, BP 20.8 C
TISSUE



3501
Blood






3502
Blood















3503
Ereath









3584
Ereath











EIEOSOBE BOUT!



Inhalation






Xngestion






































AIALTTICAL
BETHOD


SC






















GC/!!S









CC-IS












IUHEEB
OF CASES









4















8









54 (387
samples)











IAIGE



a] 0.403-0. 593*110 (E-3)
1» 0.545-0.847*110(8-3)






a) 5.015-16.387 ag/«l
b) 9.160-11.050 ug/»l















Hot detected-79. 0 ug/hr









Hot given












HSAI |

1
I
a) 0.494M10(E-3) |
b) 0.6611I10(E-3) |
1

1
I
1



a) 10.41 + or - 3.76
uq/ml
b) 12.88 + or - 3.31















22.7 ug/hr









3.3 ng/1
oeoietric











GUIEiL IIFORBATIOI



a) Mo trickloroe thy lens treatnent
t) 100 ppi trichloroethylene
Banqe and lean foe 6 hr period

20-26 vr old students, wt 62-77 kg.
CE1CRIMTID BTDFOCABBOHS; ALCOHOLIC
EIVMACBS: BIOOD: BLOOD PLASBA;
OSIII: BETABOLITES; BETABOLISB;
AUDITS; SEBSJHT
--- -
a) After 0.5 q/k
-------
  Icetic acia ethyl eater
  H1-78-*
  C(-68-02
  Bl 88. Id, BF -83,6 C,  BP  77.15  C,  T? 100 II 3g at 27.0 C
iissnz
3505
E«ath
3506
Enath
_
ZIEOSOBE goal


minicii
RETROD
SC/BS
SC-SS
irasEts
or c»sss
8
5« (337
saiplas)
f SJfSE
I
lot detected- 1«l»TICH: BETIEOLISB; BII1BOUTES:
( PCPOllTICH ElPOSOSBi JBBlll »IiS
1 _ .
BEFES5SCE
Contla, J.3-.
CaBpr B.J.
telch, E. E.
1»75
irdilTes of
iDnicouectal Bejlth
30 CJ) =290-395
EiotaszjDStl, B. K.
BcaBeao, G. 9.
C'Keill. H.J.
1979
Coacnal of Aaalrtical
Tolicologi 1:225-234
tcttlc acil. allrl *««  (9 CD
Icetic atria. 2-prapeirl est«r  (3  CI)
"1-8T-7
CJ-B8-02
*t IOfl.13. SP 10« C
I 1ISS01
1
3507
treat!











titosats scan













lutmcit
GC--TS












1 imsss
1 Of (USES
5t [387
sai pies)











I IKE
Rot fire*












BEil
0.296 ng/l
Geometric











GEIIB1L 1»F05BJTIO»
naaued at 25 C at 3 7iO ai B?
Jtf . *T occurrence
l<:»er a»J upper one-Sign limits
0,0»3 aid 0.435 nq/1

BeaItkT< T9-35 rr old, coosioHlxr,
•Ttan blacks aid caocasiais.
Chicago. II. Bigiflly contiolled
expcriaentBl condltiois.
tll»9; 1ICOG01S; IILI1IOIS; IDHITS;
CEiCRimirn trosociseois; TOUTIIE
CS01.1IC COBKWDS; BULTB BlZ>BIS:
HBIHTICII-. BETISOHSB: BETIBOUTBS:
ICPOLlTIOfl riPOSOil; tllBiS IEEIS
EEFEE29CE
FTOtOEZfESlli, 3. K.
C'«eill^ B^jJ
1979
Journal at lealrtical
Toiicology 3:225-230









-------
ic«tic acid, butyl ester
1S3-8«-«
C6-B12-02
B« 116.16. BF 126 C. TP IS •• Bq at 25 C
iissns
3503
Heath
3509
Breath


ErPOSBBE FOOT!




IHlTTICAl
flETBOB
GC/BS
GC-BS


JDlEla
OF C1SSS
8
5» (387
Maples)


EMGE
Hot givea-41.0 ag/hc
lot given


BEM | GtlEHL IHT08HTIOS
1
1
9.1 ug/hr (Ccatound related to aoraal
I tetabolisi. So other details given
|C cyoqenic saiplinq technique.
1
inealthr illitairy and civilian-
(eiployees. U.S. tic Force school of
| Aerospace Beaicine, ages 23-47 yr. 3
jsioters.
1
|MSZE«ES; CBIOP.IMTED BTDBOCH.BOHS;
|C FLOS HE OBGHIC COBPOOSDS;
ICH10BOBEHZIIIS; FIOOBISE COHPOIUDS:
IEHI1TH; llCCHOLS; TEIAS; 1DU1TS
1
|
0.200 ng/1 | teasuced at 25 C and 760 la Bq
Seoaetric , I 30. «t occurrence
1 lover aid upper one-Sigaa lliits
1 0,055 and 0.139 nq/1
IBcalthy, 18-35 yr old, nonsaofcinq.
I Chicago, II. Bigidly controlled
I
)EB!»TH: tlCOGOlS; I III SOI S; IDOLTS :
| CItOBI!HTE5 ETDBOC»BBO»S; VOI»TI1E
| CTGIHIC CODECOHDS; RZkLTB SUZiRCS;
II1B1UTICK: SETiEOLISn; HET1E01ITSS:
| FOPHL1TIOII IIPOSOBS! OSB»H 1BE1S
BEFERERCE
Ccn*le. J.P.
Caap, B.J.
Kelch, S.E.
1975
Irchives of
Environaental Health
30(21:290-295
Krotoszynski, B. K.
Craneaa, G. H.
O'Neill, B.J.
1979
Journal of Analytical
Toxicology 3:225-23*


Icetic acid, octyl ester
112-1H-1
C10-B20-02
If 172.27, BE -38.S C, BP 210 C
tissue

3510
Ereath













SIEOSOHE ROUT!
















»»»trric»i
BETHOD
GC-SS














808 EES
OT C1SSS
5» (387
Saaples)













HUGE

Rot given














SEkl | GEH'BAL INFC5SXTTC*
!
0. 168 ng/1 I Xasarei at 25 C and 760 >a Rg
Geometric |«.U occurrence
t lever and upper one-sigaa liiits
|0.0»2 and 0.679 nd/1
1
(Bealthy, 18-35 yr old, nonsmoking.
I urtan blacks and Caucasians.
(Chicago, II. BiqidlT controlled
jeiperiieatal conditions.
(BBS4TH: HCCHOIS; IlimOIS; M91TS:
|CB108I!HTEB FIDBOC1BBOSS; ?Ol»TIL!
ICBGMIC C09PCDHDS: BEAITH BIZSSDS;
| IIHIHTICH; 8ET1EOLIS9; BF.TKOLITE5:
| PCPOL1TIOI EIPOSOBE; D5BAS AFEAS
1
BEFEBERCE I

rrotoszjnski, B. K.
Brtinean, G.B.
O'Seill, H.J.
1979
Journal of Analytical
Toxicology 3:225-23«










-------
    Icetic acid, phenyl- (8 ell
    Eexzeneacetic acid (9 CI)
    103-82-2
    CE-B8-02
    BS  136.1«,  BE 76.7 C, BP 265.5 C,  T? 1 •• Rq at 97.0 C
tISSOE

3511
Breath












EXFOSDBE BOOT!















1S1IITIC11
HETBCD
QC-BS













HOHBEB
OP C1SBS
54 [387
sag pies)












HUGE

Vot given













SE«»

0. 161 ng/1
Geoietric












S!IIE»L MKJSaaTJOH

Eeasnred at 25 C and 760 11 BS 161.2,  HI 276 C, BP 227 C
I1SSBE
3512
Breat











IIFOSD55 ROOTE












HJLItlCH
SETHcn
5C-BS











SOBBFE
or cisEs
5* (387
sanp es)










BIISE
Hot given











K»J
0.115 ng/1











CltlSll IirOBUTIOl
feasared at 25 c and 7CO » Eg
Ic«er and apper one-Sigia Units
0.038 and 0.3«9 og/1
Bealthy, 19-35 yr old, nonsmoking*
nrtao blacks and Caucasians.
Chicago, It. eigidly controlled
cxperinental conditions.
tBIJTB; JICCBOIS; IltlHOIS; «DDLTS;
CBI05IMTED EIDROCIEEOBS ; V011TILE
CFG1M1C COICCDIDS; RI4ITH BiZlBUS;
IIHlItTICN; BEIJtOLISS; HEI1EO11TES;
ICPDLITIOH flPOSDPE; 1BBJLB IBEJS
1 SEFESEHCE
KIoto«,S£Xi, M.
C'Keill^ B. J.
1979
Toxicology 3:225-23»








tcctic acid, propTl ester
1C9-60->
C5-B10-02
II 102.13, HP -92.5 C, BP 101.6 C,  »P 10 In tig  at  23.8  C
1ISSOE
3S1J
Exeath










1
IFOSOE; BOTIIE













SfTBOB |
GC/SS










I
1
OF C1SSS
8










I
1
SJKGE
Hot detected-2.0 ug/hr












HEX
0.5 ug/hr












GEHBJL IWFO«31TIO>
Ccipound related to norial
•etabolisn. Ho other details given
Cryogenic sampling technique.

Sealthy military and civilian
eiployees. U.S. lir Force School of
Aerospace nedicine, ages 23-il'7 yr. 3
siokers.
IISIME5: CBICBIHITIB HTDBCC1BBOSS;
CG10SIHE OESinC COBPOnKDS;
CElCBOBSlimtS; FLDCTHE COaPOUKDS ;
ISinH; XICCBO^S; THIS; ITBITS

BEfERBKCS
Cockle, J.P.
Canp, B.J.
Delch, B. E.
197S
Archives of
Environnental Health
30(21:290-295







-------
Icetic acid, propyl ester
1C9-60-4
CE-B10-02
BS 102.13, (!E -92.5 C, BP  101.6 C.  It 40 •« Hg at 28.8 C
                                                                                      (COITIROZD)
1ISSOB
3514
Breath

ZT.POSOBE BOUT!


AUITTICAI
BETHOD
GC-BS

HOBBIB
OF CJSSS
54 (387
sai pies)

BHGE
Not given

BEi«
2.» ng/1
Geometric

GEH5AL IKFOBBATIOH
Measured at 25 C and 760 •• Eg
49.4* occurrence
letter and upper one-sigaa liaits 1.1
ana 5.2 nq/1
Healthy* 18-35 yr old, nonsioking,
acfcan blacks and Caucasians.
Chicago, II. Rigidly contcolled
ISEITH; A1CCBOLS; ILLIHOIS; ADULTS ;
CELOBIHATEC BTDEOCA5EOSS; TOHTIl!
CEGtlTC COHECH!IDS: BE1LTH BI2JECS;
HB«liTIOI(: BETJEOLISS: BETASOLITES;
ECPmtTIOl EIPOSaBE; HBBAH IBEtS
SEFEBEHCE
Krotoszyoski, B. K.
Braneaa, G. H.
O'Seill, B. J.
1979
Journal of Analytical
Toiicology 3:225-231

 cetic acid, thio-  (8  CI>
 thanethioic acid  (9 CD
 07-09-5
 :-H»-O-S
 « 76.11. HP <-17 C, 3? 93 C, TP 1 » Hg at 50.0 C
USSOE
3515
Breath


EIPOSUBI BOOTE



KltTTICtl.
BETBOD
GC-BS


KOBBES
0? C4SSS
5» (387
saiples)


B»KGE
lot given

1
MEtS
3.7 ng/1
Geoietric


GEHEE1L IBF08B1TIOH
ecasured at 25 C and 760 n H
-------
    Icetlc acid,  trichloro-
    7«-03-9
    CI-B-C13-02
    St  163.t3. If 57-58 C,  Sf 1»*-197 C
                                                                                         (COMTITOBD)
1 TISSD1
I

~
3517
Brine













EJfOSOBt ROOM IWITlcre
BETBOD


Inhalation EC






















BOSSIS
or cisss


s










1
1

1

1 i

3518 1 fhotoaetrr 1 2117
Brins 1
1
1 1

1 1




1
I 1
sitai



a; 99-5 mg
b) 5-65 119 '















-

less than t->500 mq/l











BUB 1 GEXIEIL IfFOBBaTXOB 1 BEFE5EICZ
1 f
1
I
a) Hot alien I a) Day 5 and 17 of 50 PP«
b) Sot gi»en 1 tricaloroettrlene. 6 iir/dar, on 5
| cctioecati»e days. Initial Talae, 20
1 *4 an day 1
1 t) 1 and 1« dars after 50 ppl
1 tricblaroetbfleoe, 6 tr/a«r, on 5
1 conseeatiie dars. plus etkanol
1 pretrejtaett. Final raloe, 7 aq on
I d.T 1«
I 2* br excretions
1 latinated frcm orapb.
1
1 20-26 T? old students, *t €2-77 kg.
1
1 CBtOBIBlTri BTDIOCUBOIS: IICOBOLIC
I BiHBKis; Biooi; Bicor PI.ISBI:
1 OBHE; BBHB01ITIS: BITIBOIISIf:
I ICOtTS; seism
1
1
•ot ?irea I Jfter erposare to trjcfiloroethrJene
j [at* also qiTen for age- and
I sei-specific aactalitr tram aeopltsms
| nd total icrtalitr >s coipared «ith
I portalitr of Finnish population.
1
I Iges V5-65 rx or aorc.
1
| riBUBt; JDDIIS; OEISE; COBPIS1TITI
| CIIIOITIOBS; CHLOBIIIS CBGJUIC
| CCBICHIDS ; IJCffSTBIH 1TBOSPHFBES;
1


Bailer, G.
SpassavsXi, B.
Benschler, D.
1975
Irchives of Toxicology
33:173-189














Tola, S.
Tllhanen, B.
Jfttvinen, E.
KorSala, a.
19BO
Jqoinil of Occupational
BeSicine 22 (It) : 737-700




	 t
                                                                                                                                                                                             oc
Icctoacetic acid. b«trl ester  (9 CD
Eatanoic acid, 3-oxo-« fcutTl ester  |9 CI)
5S1-60-*
   1«S. 20,  BE -3S.6  C,  DP
ussai
35t»
Bceata
I
IIKtSOBI SO9TI


AIlltlJCAI
BET9CD
GC-BE

BOBEeB
or cjsss
S« (387
salples)

J1FEB
lot givea

»!i» I or»fsn ijrrosaifior
t
i
I
0.192 tj/1 [ fejsnrej at 25 C aad 760 >i B?
S«oiettic 1 19.1V occocrence
1 lover ana eppec aoe-Sigma liiits
1 0.059 as a O.€13 aq/1
(
1 SealthT, 18-35 re old, nonsiofcinq,
( attta clactf and Caucasians.
1 Chicago. II. SiqidlT contcollea
1 «iperi>egtal cocdttions.
1
I ISUTH: HCCEOir; TIUSOIS; MH1IS;
ICELCftllkTII ETDPOC1SBORS; 1011TILE
1 CIG1B1C COJPCU1DS; BEaLTB «IZ15tS;
1 IHILITIOIt BIT4E01IS1; HIT4EOLITE5;
f eCTULttlOl EinsniE; DEBill IBI1S
L
lire sires
FrotosjTDEki, 3. IT.
Euneau^ S.9.
C'seill, E.J.
1971!
Toiicologj 3:225-23*

-------
lc«tOM 18 Cl)
2-PtOBaiOM  (9 CI)
«7-««-1
C3-I6-0
81 58.08. IP -9«.« C. BP  56.«8  C.  fP «00 •• Ba at 39.5 C
1ISSOB

3520
EE«ltk




3S21
Breath










3522
Breath







.




3523
Breath










EZFOSOBE mrai

-











































alllTTIClL
BRIOB
OC/HS





GC/BS











GC-HS













GC











inaeia
or c»sss
-
13





8











5« (387
saaples)












a) 5
b) 5










IllGE

0.22-4.87 pps





1.3-2000.0 ng/hr











lot given













a) lot given
b) lot given










RIM

0.52 ppn





500.6 ag/ir











101.3 ogA
Seaietric












a) 309.0 * or - 3.1
nioleVl
b| 20.3 * or - 3.1
moles/1








entni. nroiiiTioi

comctea fci level it inhaled aic

EealtkT alalt>

siBDBi; loitis: ansinzBZii BRBODS;
IIIBHOl
Ccipoma related to noiaal
ntabolisi. lo other details givea
Ccyoganic saepliag techaigne.

Bealthy ailitary and clTilUn
eiplorees. O.S. llr Toroe School of
leco^paec Heaicine, ages 23-47 jr. 3
tickers.
EIKIIBS; CBIOBIItlH BIBBOC1BBOIS;
CBLOBIII OBGIIXC COBPOOIDS;
CBtOSOBIIZEIIS; FL001UE COBFOniDS;
EBIITB: IICCEOLS; TZXIS; 1D01TS
«ea«Eed at 25 C and 7CO •• flg
lOOf occurrence
lewc and upper one-Siqu liaits 5«. 6
aid 181.7 gg/1

Bealtkr* 18-35 Tt old, nonsiokiag.
oxfcaa blacks and Caucasians.
Chicago, It. RigidlT controlled
eiperiaental conUtiona.
tIEITS: HCCEOIS; I1IIIOIS; ID HITS;
CElOBIllIir BTDEOCIBBOIS; fOUTILE
cioiiic coipomiDS: HHITH H»I»BDS;
IlHlIiTICl; BETIEOLIS8; HZHBOLITBS;
ECPU11TIOI IIPOSOSE; Visit SBIIS
a) Snblects taking 250 ag/day
tulfiraa
b| Controls
Significant increase (P < 0.001) la
drag-treated subjects.

lea-fasting sablccts. ages 25-«a jr.
taking dicalfiran for treatneat of
alcoholisa fee 1-7 so. (ornal.
ion-fasting controls, ages 20-55 re.
[BOG TUtlPT; Hf»ESOTa: » DOITS;
INKS
BiniBlCI

Jansson, B.o.
larsson, B.I.
1969
Journal of Laboratory
and Clinical Bethods
7« (6) -.961-9(6
Conkle, I.P.
Canp, B.J.
Reich, B.I.
1975
archives of
Environmental Bealth
30(2):290-29S





Rrotoszvnski, B. K.
Braneaa, 6.1.
d'leill. B.J.
1979
Journal of Inalytical
Toxicology 3:225-23*








DeHaster, E.G.
Kagasva, B.T.
1977
Research Coaannicatioas
in Caeiical Pathology
and Pharaacology
18(2):3C1-36«






-------
  icetonitril*
  7«-«S-8
  C5-B3-I
  SI 41.05.  IF -45 C,  IF 81.1 C. TP 100 •• Bg It 27 C
TISSUJ
3524
Breatt






ZIPOSOBJ BOBIB







iiiinicaL
HIT BOB
6C-BS






IBBBra
OT C1SE9
54 (387
sanplea)






I1IGI
lot jiie«






BUI
7.4 ng/1
Seonetrle






GIHMl motlallOl
tcanrcd at 25 C and 7«0 nn Bq
19.4* oecnirence
I»»er and upper one-sigsa Units 3.0
and 16.0 ng/1
IMltny. 18-35 re old, nonsnokinq,
oi Ian blacks and Caucasians.
Cklcago, ii. Eloidlr controlled
«ip€rlnentnl conditions.
ItZITB; klCOeOLS; IILIIOIS: UILTS:
CElOBUlTfO BTDlOClBBOIS; JOlaTIlE
CES1IIC CQBPCUIDS; HltlTB BlllSrS-
IiaiLlTIOI; HttlBOIISH; «BT»BOIITIS!
ECPVL1TIOI HPOSOBB: HUH 1EEIS
itmssct
rcotoszmski, 8.K.
Brnnenn, S.s.
c-it«ill, a.J.
1979
Journal of analftical
Toxicalogr 3:225-23*





         , dlchloro-  (8 CI)
        aictloro-  (9 CI)
7«72-29-»
CJ-C12
If S4.9t, IF -«6 to -C«.2 C

3525
Sreatli


nrracB
oc-as
or ctsis
54 (387
saaples)

lot jirca
•si" i eimii itroxBiiioi
i
10.6 nq/i | Beasarel at 25 C and 760 an Ea
Seonetric | tf.»» occerence
t Io»er and npper one-sioia liaits 2.8
1 and 41.9 Dq/1
1
1 lc*m*. 18-35 1C old, oonanoJtlK,.
1 irtan blacks and Caucasians.
1 Chicago, n. Bidiilr-controlled
1 eipcrlnental conditions.
1 HIITR: 1ICOEOLS; IILIIOIS: 1BB1IS:
1 CELOKIMTH BT080CJB9OIS: TOlaTIlE
J CIBMIC COBPTOIDS; BMIIB giZlBES;
( II»LaTIO«; HCTIEOLISB; BII1BOLITIS-
1 EC?011TIO» EIPOS08B; OBB»» 1BB1S
BlFEBtfCI
rcotasTTnskl, «.)!.
Bmnenn, G. 8.
O'leiii, H.J.
1979
Journal of analytical
Toiicolo^r 3:225-234

-------
llaaiaa, 3-lMthTltkle}-, t- (8 CI)
l-CT*tOla«. S-MtbTl- (9 CI)
1187-8*-*
c*-i9-t-o2-s
II 13*.20
1ISSOI
3126
oriaa















BI tost is BOWK
Inhalation















iiiinicii
BETBOD
CC















•oaazi
or cisss
a)
b)
c)
d)

n
91 7











IIIGI
a) 100-475 aaol
b) 200-425 aaol
c) 25-90 aaol
d) 175-415 aaol
•) 2*0-675 uol
f) 40-150 aaol
all are /aol ereatlalae










- -
nil
a) 336 BBOl
b) 3*0 aaol
c) 38 aaol
4) 289 aaol
e) SI 2 aaol
f) 72 aaol
«) «S » or - 23 aaol
111 aM /aol
creatinino










GIIE111 IBPOIB1TICI
a) Bethyl ckloride aiposue, 30-70
KB
b) Retkyl cklorido exposure, 30-50
KB
c) Mtkyl eklorida oapoaan, 40-40
EFB
d) flctkyl cklorido oapoaaro, 40-70
a) Sotkrl eklorida exposure. 35-65
Fpa
f) Batkyl ckloride azpoaar«. 50-90
q) coatrcl
laaple* taken 2X/day 7 days
Ckaalcal plaat vorkera
IITIEKIIIOS; 1DOLTS; VIIBE: 1E1LTR
Biiisos; innsniu MBOSPBIBES;
IIBU1TIOI; IET1801IIES; CBIOIIIITED
BItBOC>B«OI5
1
BEtEBEICE
Tan Doom, B.
Bora, P.J.I.
Benderaoa. P.I.
Beavara. J.
Tan Borgia, T. J.
1980
International IrckiTaa
of Occapational and
EBTironaeBtal Bealtk
46:99-109








llaaln, 3-l«-C*-kT4ro>r-3-lodopbaaoxr1-3.5-Uloaopaanrl|-. 1-  18 CH
l-Trroaia«, e-(»-kT*roiy-3-lo4ojko»Tl)-3.S-411odo-  (9 CI)
CEU-02-3
C15-812-13-1-0*
II tS1.01. tt 236-237 C (lac)
IlSSflt
352T
Blood,




tlKSVVS JOOTt






iiitmciL
HCTHOD
III





•VIBZS
or cisss
a) 2*3
h) 42
O 27
d) 22



»MS
a) 80-250 aoytOO al
b) 273->1»Ofl no/100 al
c) < 36-145 og/100 al
d) 174-410 (0/100 al



BE1I
a) 183 B4/100 al
b) lot giTBB
e) lot jlTon
d) 275 aq/100 al



GIIHU IirOSBlIIOI
a) CatkTtold Tolastoora
b) Hypoctkrcold patioata
c) HTpotkTTCld pattoata
4) Boraal, proqaant mien
Halt of dotactloa, 36 nq/100 al

iciBoiis; iiisoiBmt BRBODS; BLOOD
SIBOS: TIMS
(ETEBEICB
BtO*Bl I.I.
BotkeaBT> •>•
197*
Joaxaal of
Pkaraacoatical Sclencea
63 («): 1214-1217


IllTl aleokel (8 CI)
2-Itoiwa-l-ol (9 CI)
107-18-6
C--86-0
» 58.08, » -SO C. BP 96-97 C. TP 10 aa fq at  10.S C
1ISSOB
3528
tiaath









EXtoson mm










tin men
BETBOD
ec/ns









inan
or cisss
8









11TCI
«ot d«t«et«d-9.S ui/kt









•Ell
1.3 no/kx









etiitii iBroiBinoi
Ccipoaad relatad to aozaal
•otabollaa. lo otkoc detailt 9lT*a
Cryogoalc aaapllai tockuiqne.

••altkr ailltarr and elTilian
«aplOTMl. D.S. lie force School of
Icrospaea n«liclo«, aq«s 23-47 TT. 3
aaokeca.
EllZNCS; CIIOBIBKED BTDIOC1BBOIS;
CBIOBIII oieinc coipomnis:
CBtomiBiziKS: FIIOBIIS coamms;
IBIHI; 11CCBOLS: TZMS: HOHS
IEIBIEICS
coakl*. i.e.
Caap, S.J.
••lek, I.E.
197S
IrekiTca of
EBTiroaautal Boaltk
30(21:290-295






-------
linings
7*29-90-5
11
lt» 2«.98151, » «60 C, BP 2327 C.
                                   TP 1 •• Ig at 15*0 C


:
TISSai EIPOSSSI ROOT!
lorta
1
1
3 5 JO
51004,
sera a
31
rod.
2
1
1
f
1
1
1
1
1
1
1
1


1ULTTIC1L
BETBCD
11
US
1
t
us
115
I OH BIB
OF C1SBS
2
1
a) «
b| 69
c) 23
U f«
It 30
:J 57
1) 3g
E1IGS
8.5-20 ag/s [net vt)
a) lot applicable
b> lot applicable
c> lot applicable
d) lot applicable
a) Vot given
b) Sot given
c) lot given
>t lot giTei
>) lot given
:J lot given
[| lot given
BUI
11 » or - 8  I Hodge, K.C.
desCerrioranine I 1^80
d! Final leasareaant, dar 290 I lancet 2<8196) :692-693
Levels sLoaed sbort-teca cyclic 1
•artatlags, and long-tera opvard 1
trend luting treataent. E3tiaated t
(cos grapb. 1
36 Tr old aen vitV dialysis |
encephslopatbv. |
1
Irileptlc seizures, svoclonlc larks, I
CialTsis eaceptalopatkr, 1
etteodvstrachv, prosisal aiopatliT. 1
1
noiiim; i»troos STSTEB OISEISZS; I
BiTODiiiisis: anus; DSITID KIIGQCB: t
EtOCD SEBHI |
i
1
a) controls I Gilli, t.
b) Drenic patients on besodlalrsis. I Farlnelli, 1.
Elalrsate. 7.7 * or - 7.51 og/1. pH | Fagiali, I.
7.3 I DeBastlani, P.
c) TIretic patients on internittent I Rnoncristiani, 0.
rerltoneal dlalrsls. Dlalrsate, 10.07 I 1480
« or - 5.3 ag/1, pa < 5.5 | lancet 2(8197) sT»J-7»3
>IDIET DI SEISES; 1LOHI»DB; IRltS; I
HCOB SEltll; ITIII: BIBOD111ISIS t
1
t
i| Control: fron U.S. I llfroy, i.e.
t) loalialTZcd patients 1 Regg. 1.
c) DialTT«d patients I Crasvell, p.
encepItalopatliT t Inerican Journal of
1 Clinical nutrition
Orealc patients in U.S. and 1 33:1509-1516
Instralia. Sose died of dialysis I
msTmti: limit STITES: nno?siEs: i
IIIOIET OISIISES; 1EETOIS STSTIB |
CTStlStS; BOIES; BBlT-f; 8E1BI; LITER; 1
uses; losciis; S?LIEI: EEBCDIILISIS: i
ItC Slim: HE11LS |
1

-------
llCliniB
II
Itl 26.981S4. -IP 660 C. BT 2327 C, T?  1 ••  Hg  at 15*0 C
                                                                                       (COBTIigSD)
1ISSQB

3533
Sralo

















3534
Praia











3135
Bair















3536
Hair










EXFOSDSE BOOTS





























































iiittncu
BETHOD
11

















US









































ItllBES
or CISES


















a) 16
b) 30
c) 57
d) 38


























-
a) 42
b) 40










llBSS

a) 8.0-19 gg/g (rat vt)
b) 22-23 ug/g (vet vt)
c) 6.9- 15 gg/g (vet vt)
d) 12-22 ag/g (vet vt)
















a) lot given
b) lot given
c) lot given
d) lot given



























a) 1-17 ag/g
b) <1-29 ag/g









(HIT
Bill

a) 15 » or - 4 «g/g
(vet vt)
b) 23 » or - 1 ag/g
(vet vt)
c) 11 * or - 2 ag/g
(vet vt)
d) 15 » or - 5 ng/g
(vet vt)












a) 2.4 * or - 1.3
b) 4.1 * or - 1.7
no /kg
c) 8.5 » or - 3.5
•q/kg
d) 24.5 « or - 9.9
•I/kg
Defatted saeples






















») 5 ug/g
b) 5 ng/g
ledians








?HS!)
GE1IB11 IIFOSHMIC1

a) Bales, eerebree, 9 sabjects
t) Teeales. eerebmn. 2 sabjects
c) Bales, cerebellum, 6 snblects
i) Tenales, cerebellua, S subjects

Tron a groat of 61 autopsies.
forensic nedical eianinations, Japan.
Bales, nean age 40.6 rr. Feiales,
nean age 37.4 vr.
T11CI niBtllS; 10TOPSIZS; JIPII;
iioBiinB: iBSERic; CIDBIUB; COBALT;
etBCain*.: COFPZB: MOB; BSBCUBT:
IIBIUB; BlGICSIUfl: BA1611ESB:
IOBIDIOB: iniBoit; sciiDing;
siLEBioB; Timim: TiiioioB; zinc;
GCLC; BBOBIII; lITEli KT91ITS;
CIBEBBH1; CtEIBEHTIB; H!1BT: [HJSCLES;
FHCB11S; SPXEEp; 1I1GS; lOBll;
BITH.S: coipiBHTirs ETiLomcas: SEX;
rcBEisic BICJCHI
a) Controls fron O.s.
r) londialvxed patients
c) Dialrxed patients
d) Bialried patients vith
encephalofathf

Oreele patients in O.S. and
lastralla. Sone died of dialysis
encepbalofattT.
lOSIDlLII: 01ITED STITIS; 10TOPSIES:
II It BIT 9ISE1SES; HIBTO03 SIS1EB
CISI1SIS: BCBES; BB11J: BEIBT: LITEB;
IBISS; IDSCltS; SPlItiT; RlilODIllTSIS;
1IBBI1H!!; BEIU.S
leviev. 24 representative
cte-aaaly*is treataents are
tabulated. Ibe feasibility of a
bclistie, no-vash policy for bair
analysis is cut lined and supported.
ftTIEv; TP1C! riMEITTS; BUB;
mSTfiH.lt; atlSO«EBEIT NETBOOS;
gitus: pBoums; COBPIBITITE
IISEIIC: B»BKIS; BBOIIIE; ClCTlm;
cucin-i; cHicEiiE: CBBOHIIIB: COMIT;
CCPPH: SIIH0B: sEBBtnvi; eoiD:
icon!: IBOI: iiiTHiinB: lilt:
BI61ESI»; BU61I2S1; BEBCDBI;
tClTB9E!TJB: HCKtl: PBOSPHCBOS;
iciisstvii: BUBIDIOB; snumB;
SIUC01: SIIVB5; SODIVB; SIBCIIIIB;
tlic: ilacoiion
a) Controls
c) Boltitle sclerosis patients
Saaples fren 7 scalp sites in each
•vc^ect.

CI11B1; 1E01IS: CEITBll BtBVCOS
!TSTZ9 DIS'JSES; 3»IB: KIDBIBU!!;
IlCHIIt; C1ICIOB: CB10BIBE: COPPER;
ecu: Km*!: >iiisiiis:; IESILS;
S1I»«11!; SIITEl; SCDIOH; SOIF3B;
71110131; TIIC

BEIBBEBCE

Tvkava, B.
snzaki-Iasaaoto, B.
leaao, 1C.
Terai, B.
1980
1 retires of
Enrironnental Health
35(1):3«-44


•









Alfrey, I.e.
Heqg, 1.
crasvell, P.
1980
laerican Journal of
clinical latritioa
33: 1^09-1516







cbittleboroagh, G.
1980
Science of the Total
Environment 14:53-75













Byan, D.E.
Bolzbecher, J.
Stuart, D.C.
1978
Clinical Chemistry
24(11):1996-2000







-------
II mi cai
7g29.90-5
II
Its 26.98154.
              HP 660 C. BP 2327 C.  7P 1  •• Ha, at 1590  C
                                                                                     (COITIIOBD)
1I3SOS

3537
Beart

















3538
Mart












3539
Kidney


















BIPOStJBS BOOtS






















































atunxcii
IRBOD
U


















1>3













U



















BOMBS
0? CISBS
a) 4
b) 2

















a) 16
b) 30
c) 57
4) 38










a) 6
b) 2


















sues

a) 4.7-26 ug/g (net «t)
b) 23-34 a«/9 (oet «t|

















a) Hot given
b) lot given
c) lot given
d) lot given










a) 10-41 ag/g (net »t)
b) 12-12 ag/g (net lit)

















flEIT
•Ell

16 » or - 9 ug/g (««t
•t»
b) 29 * or - 8 ag/g
(«et »t|















a) 1.0 * or - 0.8
eg/kg
b) 6.9 » or - 10.6
ag/kg
c) 22.5 » or - 20.5
aq/kg
d) 42.7 « or - 22.9
•g/kg
Defatted saaples





a) 20 » or - 11 og/g
(vet »tj
bj 12 * or - 0 ag/g
(vet «t)















PIGB)
GEIIBll nPOBUTXCB

a) Hales
1} resales

tcoi a <|coap of 61 autopsies.
forensic aedlcal examinations, Japan.
Bales, aaan age 40.6 ft- Females,
•ean age 37.4 vr.

1B1CB EI.BBZBIS: 40TOPSIBS; J1P1S;
iioBUns; iBsziic; CIDUOB; COBILT;
CEBOSTBB; CCPPBB; IBOB; HEBCOBI;
IltlOH; IfaGBZSIVB; UBeiBBSB;
BOEIDIOHl IBIIBOBT; SCaBDIOB;
SntBIOIt; TIIMIOI; TABIDIDI; ZIBC;
«cit; BBOHUi; tirra; KIDIBTS;
C1BBBBOB; ClBEBniOH: HB1BT; BOSC1BS;
SIICBBU: SPIEM; LOK3S: 10BT1;
BRILS; COBPUMIV8 BVilOHIOSS; SSI;
fCBJISIC BiriCIBI
a) control! tiow 0. S.
t) Bondlalyiei patients
c) olalysed patients
d) Halted patients >ith
•acephalopatby

Dteiie patients in O.S. and
lastralla. Sone died of dialysis
encephalopatfey.
losnuii: omsD SHTBS: IVTOPSIBS;
HC8BI DISBISBS; IBBVOOS STSIBH
tlSHSBS! BOIES; BEIIH; BElBTt 117 IB:
loses! nosciis; SPLBB>; BBBODIIITSIS;
11CBIBHB; BB1US
a) Bales
t) reiales

fron a gtonp of 61 autopsies.
forensic ledical exaainationa, Japan.
Bales, aean age 40.6 yr. Feaales.
aean age 37.4 yr.

1D1CE BLBHIITS; IOTOPSIBS; JlPH;
HOnBDR; IBSIHICJ CiDBIOB; COB1LT;
CEBO»IUR; CCPPBB; IBOB; BBBCOBTj
1BIIOS; BaGIESIUB; BalGaBSSE;
fnEIDMB; IBIIHOBT; SCaHDIOB;
milTOH: TT1MIOR; T1BIDIOB; ZIBC;
CCtll: 9BOHIBE; LIVES: KIOIETS;
CIBZBBOB; CBBIBELUJB: BE1BT; HOSCISS:
fllCBBIS: SflEBB; LOBSS; JOBTi:
BITUS: COBPUtTITB BTAIOATICHS; SEX;
PCBBKStC HIEICIHE

BBFBBBVCB

Tnkava, B.
Suzaki-Tasanoto, B.
Isano, R.
Terai. B.
1980
archives of
Bnvlronaental Health
3S(1):36-i)4











alfrey, I.e.
Regg, 1.
Crasvell, P.
1980
liecican Joornal of
Clinical Bntrition
33:1509-1516







Tnkava. B.
Sazaki-Tasaooto. n.
liana. E.
Terai. B.
1980
archives of
Environaental Health
35(1): 36-40













-------
llaelaas
T«29-90-S
II
Itl 2C.9S15I. It CCO C. If 2327 C. ft 1 M Ba It  ISM C
                                                                                      (CORIIOED)
1XS39I

35*0
llvor

















35*1








35*2
Lviq

















35*3
Lung








NCOSOIS 1OOT1























































1I11TCZCAL
BCTBOD
•1

















us








•1

















us








IBBBM
or CISBS
a) 9
b) 3

















a) 1«
b) 30
4 57
d) 38








a) 2
b) 2

















a) 16
b) 30
d 57
d) 38








B1KB

a) 10-25 ag/g (vet *t)
b) 5.5-20 ag/g (vet vt)

















a) lot given
b) lot given
c) lot given
d) lot given








a) 18-100 ig/g (wt vt)
b) 10-23 ag/g (vet vt)

















a) lot given
b) lot given
c) lot given
d) lot given








RZ1B

a) 18 * or - 6 ag/g
(vet vt)
b) 15 * or - 7 »g/g
(vet vt)















a) ».1 » or - 1.7
b) 25.5 « or - 33.1
agAg c| K1 * or -
12* ng/kg
1) 301 « or - 21*

Defatted saaples






a) 59 » or - 58 ag/g
|v«t vtj
b) 17 » or - 9 ag/g
fvet vt)















a) »3 » or - »3 ag/kg
b) 75.2 » or - 77.3
•g/kg
c) 89.5 * or - 76.8
1) 215 « or - 220
ng/kg
Defatted sanplea.





SEIIIll XBFOIBHIOB

a) Bales

Iron a groap of 61 aatopsias.
forensic nodical •xaninatlons. Japan.
Bales, aeaa age «0.6 jr. fesales.
seen age 37.1 yr.

IBICB xiSBsns: IOTOPSISS; JIPIB;
llOBIRvB; IBSniC; C10RIOS; COBUT:
CBICRina; COPM1; IIOI; HBBCVBT;
HtlDB; SISIISIOH: R1IG1IISB;
inEIDIHI; 1ITIROBT: SCIIDIOR;
SHEim; TITIIIOR; TIHDIUB: Hie;
eciB: Btoiiit: um: KDESTS:
CIBZBBM: ciBZBEiuiR: BEIBI; HOSCLES;
E11CBI1S: SPtBBB; LOBGS; 1CR1;
IRUS; COflPUlTIVB ByilDlTIOBS; SSX;
ICIIISIC BKICIIB
a) Coatrols froa U.S.
t| loaaialyxed patleats
c) tlalyzed patioats
4) Blalysed catiaats a 1th
eieepkalopatby
flrenic patleits la O.S. and
laatralia. Soae diad of dialysis
eaeepbalopatby.
llSnilll; OUTID STIIIS; lOTOtSIBS;
If DIET BISB1SB5: RSTOOS STSTBR
t is lists: BOIES; mil; BBIBT; iirsi:
IDIGS: Rosens; SPLIE*: HHOtimsis;
I10IIIOR; H1111S
a) Rales
1) Teaales

froa a groap of 61 autopsies.
forensic aeUcal oxaaliationa, Japan.
I tics, lean ago *0.6 yr. Peaales.
aeaa age 37.* yr.

T11CB BIBBBItS: 10TOPSXZS; JlPHi
iioniins; IBSZIIC; CIDRXDR; COBUT;
cc
-------
ilmlm
7«S»-«0-5
11
Itl 26.9815»,  at 660 C, BP 2337 C, TP 1 •• Bg at 15W  C
                                                                                   (OOVTIBBXD)
IISSBE EirosotE BOWB IBUTIICU
BETBOD


35«» Ba
BaBcte













1
1
j


3515
Basel*
1















US


I
f
1
1
1
1
1 1

t





35« u
BttBBSJ
or ctsss


*1 *
b] a


















) i«
1 30
) 57
1 38












1115! |
1

|
a| 8.3-16 gg/g («et >t| 1 a| 13
b) 7.4-29 «g/g (Mt >t| 1 (rat
1 b) 17
1 (*et
1
f
1
1

1
1

1

r
i
i
i
i
i
a] lot gtrea I a) 1.2
b) lot livei | 11/tg
) tot glrea I 6) 2.S
) Bot given | eg/kg
I e) 9.1
1 ag/ltg
1 d) 1«.S
t e?/'Jt?
BE1B | SHIIlt moiBHXCI
1
1
1
+ or - 3 ug/g f a) Bales
vt) 1 II Tevalev
+ or - 7 ug/j t
vt) 1 fro i * ?rc«f of 61 autopsies.
1 fcreaslc aedlcal exaaiaationa, Japa
f a*a2*av tutt a^e 40. C fr* faaalea.
I aeaa a Ualraed patleats
1 d) Clalned patieata vlth
« or - 14.6 | encephalopatbr
1
* or - 13.7 | Create patients la (r. 3. aad
; Joetralia. So»e died of dial/aix
I
1
1 llfrei. I.e.
1 B«gg. 1.
1 crasrell, f.
I 1980
1 laerlcan Journal o
i clinical (otcitioa
1 33:1509-1516
i






t



I Defatted sanples eaccpfcalopatlf. 1
1





t
1 1
5 1 a} 9.3-30 nq/q fust vt> la] 15 *
Pancreas 1 1 t) 2 I b) 18-25 «g/g (vet vl) I (ret «t)
1 II »> 22 *
I f«at vl)

i
1


1
1










insTBiLii; nme STITIS; JBTOPSISS,-
Kinzr DISUSES: IZBTOOS SHTEB
CISUS'3; BOIES: BBalf; 1Z1IT; UTJB;
I1BGS; BOSCLIS: SPLEII; HSlOIIlltSIS;
lIOBinB; BE1J1S


or - 9 pj/9 1 •' Bales
| t) Teaales
or - 5 ag/g 1
f tram a graft o- 61 autopsies.
| Coreaslc avdical eiTaaiaatioar, Japan.
1 Bales, swan ag* *0. € rr. Peial«8.
I aeaa ag« 37.* TC,
1
( SMC* nlBEBIS; ItlTOPSIES; J1T1I;
| IIUBIITB: ItSEBIC; CaDBIOB; COBllT;
| CESCflll': CCFPBB; IBOJ; REBCOEIi
| IBDIH!I; IlCBZSItIB; B1BS1BZSI;
| SOBIDITI; linBOIT; SC1IDHJB;
| SUHI11; Tinting; fl I1BIOII; ZIIC;
t fiCID: BBOBIBI; I.ITEE; XTOIETS:
| CltEBRlH: CIBtBEUOB; BSlIf; BVSCLXS;
I >1ICIB»: SPIXE*: lOKS; lOSTl;
| BIT11S: COBPU1TITE CTILD1TIC1S; SIX;
| fCIIISIC HICICIII
|
t
1
t
1
1
1
I
1
1 Tokava, B.
t Sazakl-Tasaaoto, I.
1 laaao, t.
1 lerai, B.
1 "BO
1 IrctUes of














1 lOTlronaental Bealth
1 35(1):36-««
1
1
t
t
I
f
1
t
1
1
|
1













                                                                              (Btlt PtGt)

-------
7129-90-5
II
Itl 26.4115*. W 660 C. BP 2327 C, fp  1 aa Hg  at  1540  C
nssai

3547
Splem

















35*8
Spleen













Exiosns icon



































alUTXICU
IR10B
u


















us














BOBBIE
or CISES
•I s
b) 3
















'
a) 16
b) 30
0 57
1) 38










1
11ISI

a) 6.7-25 ag/g (««t «t)
I) 16-»4 ag/g («et it)

















a) lot gi»«i
b) nt gl»««
O lot gif*B
d) lot gi»«











RIM

a) 14 + oc - 8 ng/9
(net lit)
b) 26 * or - 16 *J/g
(»«t rtl















a) 2.6 » or - 2.1
•i/kg
b) 35.3 * 01 - 72.3
•9A9
C) 2»3 » or - 250
aqAg
3) 493 • or - 463
•9 A?
Mfattcd saiplaa






CtllllL IlTOlSUIOH

•} lain
t) f«Ml«S

Txoi a gcovp of 61 attopsics.
fot«»lc aeileal axaaiaatloia, Japan.
Bales. Ma> «g« «0.6 yr- r«aleB.
•*a> «g« 37.4 TT.

»ici ncims: IBTOPSIIS; juu;
ittnna; iismc; cutiva: COBILT;
CtBCSIBS; CCPPHJ I10PJ B1JCUI1;
IICIH«; laSIISIOB; nlURESI:
»UBiT)in»; ininont; scuoira;
itiinaHi TiiuiDi: TIHD«B: zinc;
CCID: BBOBIItS HTBB: KIDBITS:
CIBBBBCI; citniiiaa: BEIBI: susais;
EUCBZI3; spun: IDKSJ ICBI*;
BITUS; COIIPUHin ETJLniTIOIS: SXI;
TCBIISIC KBICIIX
a| Controls flroi 0. s.
t) tmtitlmS patl«nts
e) ui»lri«a fatluts
d) DlalT>td patltnti «lth
•accpaalopatkT

Ircslc patients ta U.S. asd
Usttalla. Sow di«d of dialysis
•aecpaalopatkT.
lostBiui: miTED STiTis; inapsiss;
IIC1EI DISUSES; niTOOS STSTI9
rijzisis: BOIES: BIHI; min; IITBB;
inss: aosciis; SFIIBI: BEBODIIIISIS;
iitniw; units

BIIEIEVCE

Takava, B.
SoiaKi-Tasnioto, a.
liana. It.
T«al. B.
1*80
Archives of
tSTllonieBtal Baalth
35 (1(: 36- 44











tlfMT. »-C.
B^g, i.
Ctasvell. ?.
1980
laericaa Joarnal of
Cliaical Bntritton
33:1509-1516








1318-09-8
IIKT CODPOSmoi USR1IOII CB DIBBTMBIIBB
nssnB
3541
latastlie


ZXtOSOBZ BOOt!
Ingest Ion


MHTTICH
nrrncn
tn


BOSSES
or ciszs
a) 21
b) 32


IIIGE
a) lot glT«o
b) lot girtn


•an
a) 0
b) 3.20110(1-5)
flb«u/g
Ish «t
?fe

SHIBII HfOBBlTICK
a) Controls
t) Kesldeiits witb 1014 ten, high
l«tal exposnu fcoi drinking
ccataainat«d «at«r
|gtopsl«s, Jflonoa wall
!!2-89 Tr old rasldeats neat t&conite
Ftocessin? plant, niaatsatt. 17-77 jr
tld controls, IHnnesota and Texas.
eilBESOTl; THIS; aOTOFSIES;
IBIESIIBES; IITEE; lOISS; DBIIUnS
««!•>; HtdSnitl EBISSIOIS;
IBOH5TBIU EC11DTIOB; (aTEB
EC1LDII01: ISBISTOS
-
BETEBEKCE
Carter, B.E.
larlor, B.r.
19SO
Environmental Besearch
21:85-93


                                                                                       (IEI1 ?JGE)

-------
   latklboles
   13 10-0«-e
   mc» COSPOSITIOI oinon 01 mtirninra
iissiiB
3550
tine
3551
law
BirOSOBB lOOtl
laaectiaa
Iag«stion
1
i
1
1
1IU.TTIC11
HB9BC&
N
Bl
•(mm
or CISBS

•1 30
b) 32
UTCB
a) tat givea
b) tot glvea
a) lot aim
b) lot gin*
BUI 1 etIIMl ZtrOBMTIOl
1
I
a) 0.3«I10(l-5) | » coatrola
flbers/g 1 b) lesideats «itk long tera. hivk
bt S.KIIO(B-S) I 1«*«1 ««a»*n lea* IrUkiij
fibers/? | ccnt«iii«t«ii «t«r
t*k *t I Ktopdw
1
t i2-n rr eld nsil«its i«*r tacanlt*
I F'oc««aiiq pl«t, linMCota. 17*77 yr
1 cltf coitrali, Rin*«ot« aid Texas.
1
1 eiinsori: Tizist umrsus;
t itTismis; irrii; luics; onntiie
i inn; iimntxii mssiois:
I IIEOSTMII EO.IDTJOI: HTIi
I icunioi: tmsios
i
1
a) O.SUtOtI-5) I I) Controls
fibers/9 1 t) lesUeit* «itk lo>« tera. blah
b) 16.21110(1-5) I level exponce free drlaxiif
fibers/g 1 ceataaiaated natex
ish »t | lotopaiea
1
I S2-89 ji old resideata neat taeeaite
1 ftocessiag rlaat, liaaeaota. 17-77 rr
1 eld coatrolSp ffiaaesota aad Texas.
1
1 HIIESOT1; IZIISi 10TOPSIBS;
I miSTIIIS; UTZI; tDTCS; DBIHtCTS
1 ntn: itDisniii insstots;
I iievsniit tctmiiot: MTBI
1 ICIIOTIOI: J5HSTOS
i
IBRIBICI
Carter* B.E.
Tirlor, t.r.
19*0
BBvlroaaeatal Reaearcb
21:85-93
1
1
1
Carter, B.E. |
Saflor^ W.F. i
1*80
Earlroaaeatal Beaearca
21:85-93
                                                                                                                                                                                  00
IrlllM, •.••-•etkrle*ebia(2-ealaro- (8 Cl)
I«neaasine, a,«'-a«UTleoebIsf2-chloro-  (9 CI)
101-ta-a
C13-B1Z-C12-H
If 267.2
I IIS301
1
1
1 3552
1 Oriae
1
BIfOSVK! B0«r
laaalatloa
Penal
1 tinmen
I IBTVOD
i
1
Coloriictrr
•maEx
or cuss
*
1 tires
i
0.0«-3.8 a«/l
| IE1I
tot giTea
etiiui iiroiuTioi
lir coneeatratloBS oalr sliahtl;
above tkrestold of detectioa (0.01
>«/c< e) .
Iiposed icriers. lev Jersey
CCCOMTIOI1I BHiUS; OBIIE; CBlOBItE
CISIBIC cotrcnos: BstsmBUR
fKIOnS: UCBSTKIU ReiBII
tETEBnCX
liack, I.I.
1S7«
laericaa ladastrial
HTgieae IssociatioB
JoatMl 3S:*26-«32

-------
intisony
1«40-36-0
st
Itl 121.75, n C30 C, B? 163J C. IP 1 •• 19 at  866 C.  10  •• Bq  at 960
USStJB

3553
lorta
















355*
Brain
















3555
Bale


















BIPOSOJE BOOTE
























































1BUITICU.
BBTBOD
Bl

















Bl




































•OBBSS
OF CUSS
3






















































B1B6B

lot given

















a) Bot given
b) Bone detected


































(IEIT
BBaB

0.01 » or - 0.02 ng/g
(net »t)
















a) 0.01 « or - 0.02
•g/g («et «t)
b) Bone detected

































PISE)
GZBEttl IBPOBSITIOB

Bales

iron n grosp of 61 autopsies.
forensic medical exaninations, Japan.
Bales, sean age 40.6 yr. resales.
i«an age 37. a yr.

II1CI ILEHEBTS; JUTOfSIES; J1P1B;
JIUBIBUB; JBSBIIC; CIDRIUfl: COB JIT;
CBSOaXVB; COPPEB; I BOB; BBBCOST;
IICI01; BlGBtSIDH; B1B61IZSE;
1B8IDI05; IBtXBOBT; 9C1BDXBB;
jiiBBiuB; TITJBIOB: YIBIDIOS: znc;
GC1C; IKOBIlIi LITEB; KIDBETS;
C!BBBBB!l; CZBISEUBB; BE1S1; BOSCLBS;
FIBCBZIS; SPIEEI; IIBGS; 1OBT1;
BIT US; COBf J11TITB ET1L01TIOIS; SEX;
KIIBSIC B1DICIBI
a) Tesales, cerebrvn, a subjects
t) resales, cerebellns, 4 sab-fects

Tton a groa; of 61 autopsies.
forensic sedical exasinations, Japan.
Bales, seas age ao.6 yr. resales.
•ean age 37.* yr.
TBICE EtlRBIISi 1VTOPSIBS; J1P1B;
ItBBXBOB; 1BSEBIC; C1DBIHB; COBUT;
CEBCBIHB: CCPPEB; XBOB; BEBCOBX;
IBCItIB; BlGltSIOB; BlBGiBBSE;
IVEIDIOB; IBIIROBT; SCUDIOH;
SE1BBXUH; TII1BIOB; T1R1DIOB; ZIBC;
ecic: BsoaxiE; LITBB: KXDIETS;
CBfBBlVB; CBBtBELLUB; RB1BT; BVSC1B5;
PIBCBB1S; SPIRB; IDICS: JOBT1;
•IIILS: COBP1B1TITB BT1LD1IICBS; SIX;
TCBIBSXC REEICXBZ
It vie*. 2» lepreseatative
pie-analysis treatments are
tatnlated. The feasibility of a
>«listic, no-«ash policy for hair
analysis is outlined and supported.
IfTIZB; TB1CI IIBBEBTS; HUB;
inSTBUIl; BEISOBBIBBT BET BODS;
EITILS; PBOT1IIS; COBP191TITB
IY1L01TIOIS: 110BIIOB; JSTIBCBT;
USHIC: EJRIDB; BBOIIBB: CJDBIDB:
CHCI01; CBICBUB; CB30BIOB; CO E JIT:
CCPPEB; GI11.I1J!!; GEBB1IIOB; SOID;
ICDIBB; laCB; 11BTR1IBB; lElt;
IIGIZSIHB: BiBOtitsE: BEBCVBT;
BCITBDIBOB; IICKIL; SBOSPHCBOS;
fciissitji; tDBioioR; SIIEBIDB:
SIIICOB; SIITBS; SODIHH; STBOBTIUH;
SVIPOB: TIB; TITHIOB: TOBGSTEB;
E1BC; ZIBCOUOB

IZPZBIBCB

Tokaia, B.
Sazvki-Tasnsoto, B.
Isano, K.
Teral, B.
15-80
Irchives of
ZnTironmeatal Bealth











Tokava, B.
Snzoki-Xasasoto, H.
Inano, K.
Terai, B.
1930
Irchives of
Enviroasental Bealth











Chlttlebocoagh, 6.
1980
Science of the Total
Environnent It: 5 3-75

















-------
;«10-36-0
St
l« 1J1.75, RP 630 C. BP 1«3« C, TP  1 an  89 at  BS« C.  10 us 89 at 960
                                                                                       (COBTUOED)
TISSUE

3556
Bale



















_— .
3557
Heart

















3558
Kidney

















STPOSflSH BOOTH




























































iBimreii
iWBOB





















B»


















B*

















.
SnaSBB
0? CaSBS





















a) 10
b) »

















a) 22
b) 3

















SiBOE

	



















.
_
a) Dot given
b) lot given
















-
a) lot given
b| Hot given

















BBXB
..





















a) 0.01 •» or - 0.02
«a/g (»e* **l
b) 0.02 * or - 0.02
aq/q («et «t)















a) 0.01 t or - 0.03
B9/g (»et »t)
b) 0.01 * oc - 0.02
aq/g (vet vt)















G!BFB»l IHFOBiiTIOH
	 	
1 revie» of >orld lltetatnre on to«
accnivlBtioti an« blocoDCeotietion of
selected to tic trace netals ill bnaai
hair and mils aafl other nansaHin
baicr fact nails* clavs and boofs.
labaiatai by geographic area.
•abjeete. «ei» «qe. axpasate
9£adieotr analytics in ppa* and
anthocity frqn ovec 000 E«tenaces.
tr«ICt; inSlBslUl CUaDat CIHltM.
IHIBICIt BOiCPE; HIttDLE BJSt: Ht»
niiMDt sooia aBEnict; somnist
• Sla; OHITII KIveDOI: OBHED STSTBS;
BUB; JJIIS! BEYICT; ABTIBOBT;
is3tmc; BO BOS: caoiimi: CBHOFntms
ccfitT; COPPIB; IBID: BBBCOBI:
IICFEI; S?lS!lI13nj TIB; TiSADIDH; ilE
FCllBTIOB; IBIBil POP014IICI3:
IIOaCCDIOimOVi BIOIBDICMOIIS; t»«B
tOtlOTIOS; POPOHTICB EtPOSOBB; RlTtR
FC11DTTOH; TB1CE BLBRBRSt BETalS
-
a) Bales
t) F«Mles

FCOl t qtaap of 61 autopsies.
fatensie asflical exaainatlons. Japan.
Bales* a«ao age 40.6 ji, Feaales*
lean »q« 37. 4 yr.

TB1CE 8189EI1S; JTITOP3IBS; J1PM:
llOBIIIOilt S8SESIC; CUDBIDB; CD E JIT;
CFSC8HJB; COPPBB; ISO!); BEBCOBYJ
IltlDX; BaGBISIOB; BtBGaBISl:
JCSIBIHI; UTISOBY; SCIHOlOM;
SIllBIOH; TI11RIOBS TaBtDIOB; ZTBC;
ecin: BBOHUB: LIT BE i KIDBKIS;
CIBIKtQK; CISEBEHOn; H5ABT; BVSCLES;
PIBCSB»S: SPIES*; LDVGS; ACBTI;
StTlIS: COIPJBiTIVS B7iL0JT30BS; S2X;
fOBIBSIC BECICI8E
a) Bales
t) feaales

Proa a groop of 61 aatopsies.
totensic aedlcal ezailnationa. Japan,
Bales, man age 40.fi yr. peasles.
aean a4« 37.4 yr.

191CE ELEMBIS; tOTOPStBS: JaPaB:
UOBTII1B; 1BSEHIC: CaDBIQBi COSUTi
ctDOHIOK; COPPBB: IEO»; BEBCIJBT;
IICIDH; 1»aS!5IOB; BaSGiBSSB;
ROBIDI3!l! tKIKOBT: SC4SDIOI":
StlEBlni; TJTHIII01; Ta»DtOB; ZtBC;
GC1I: 3BOHIBI: LIVEH; KIOBITS;
CIBEBBTS: CZBBBEUOR: HElBlt BDSCLSS;
eilCBBaS; SPIEB8; lUDlSS; JOBtl!
R'TllS; C01E»B»TI»! E»»ld«TIOSS: SSI;
fCBHSIC BEEICIBR
8EKBESCB
_
Jenkins. B.B.
1979
«Sl-600/»-79-Oll9, 18»
PP-

















Taka«a, fl.
Soiuki-taaaaoto, H.
Amanov K.
Terai, B.
1980
Archives of
In*iioni«ntal Health
35(1)i36-«a











Takaiia, H.
Sniakl-Iasumoto. n.
Itano. K.
Terai, B.
1940
archives of
?n>itonaental H«altn
35<1).-36-«a











                                                                                       (BBXT PJGB)

-------
Ittiiony
1MO-36-0

-------
IrtlaoiT
•JMO-36-fl
SI
lt« 121.75.  H  830 C. B? I63S  C.  »P 1 M 89 *t  886 C.  10 •• Eg at 960
                                                                                         (CORIIttED)































lissas



3562
Hn.,



















3563
Long















1
EIPOSOBE BOUTE










































1
1

1
1
1
I 356*
1 Riscle
4 1
f 1
1 1






























|
t









|
|













|
1
1



1IUTTXC1L
HETHOD


U




















n






•QMS*.
or cisis


a) 3
M 2



















a) 9
b) 13
c) 23




«
















M a) 5


















b) *


































I1IOE



a) 0.22-0.52 ag/g («et
•t)
b) tot giT«n


















a) 0.011-S.067 iig/g
b) 0.033-0.58 ag/g
c) 0.023-2. « ag/g
Vet *t



SIJI | GEIIUL IBFOSRHIOl
1
1
1
a) 0.33 * or - 0.17 | I) Sales
ng/g (*et it) | t) Paaalaa
b) 0.28 * or - O.ao |
>9/9 (*«t >t) j Proa a groip of *1 antepaiec.
I foienatc aedlcal exialnatiooa, Japaa
j t*l*m, aeaa aae 40.6 jr. Fcaalea,
I lean aga 37. • 7r.
1
| IF 1C! ElEHIItS: 1 CITOPS IBS; J1PK;
I I10III8R: 1BSZIIC; CIDBIOR; CO Bill;
| CRBORIVK: COPPEE; I BOB; HEJCDBI:
| IIDItH; glGIISIII; R1IG1VE5E;
| BDBIOIIB; IIIIBOIT: SC1IDIOB;
| SILIIMS: TH1EIBB; T1R19IDR: IIITC:
| C3CIB; SBOalBZ; UTEB; KIOBEIS;
| CIBIBBOU; CZBEBEUIB: BI1BI; I1TSCLES;
| IHCBEISi SHEER: LUISS; 1OSII;
| BITHS; COUPMiTIT! EHIB1TICITS; SEI;
| PCBIISIC BIOICIRE
1
1
M 0.029 B9/J | a) Controls
b) 0. 27 ag/g | b) Vorfcer qcoap I
c) 0.32 ag/g 1 c) lorker qreip II
fet vt I
Medians | Ecceaaed r«fiaerr and saelter
| vorkers, ages 55-76 jr, exposed to
1 >«a*T Mtals 1-3 iecadas. Tiae
1 tctncn zetlreieat and Aeatli 0-1.5 fr
I Centrals, ages 43-72 jt, »ao lived SO
I ka froa t&e factory. Svedea.
1
| SIEDEI; ClBl'ESS; KINETS: LITER:
| ICIGS; COBPaBaTirS ITllVAIIOIS:
| IICOSTSIll RIGIEBE; SEaSBBERERT
| ItTBODS; SITIKOJI; 1BSBBIC; CSDBItJB;
I | CISIDR; CEIOBIDR; COB1LT; COPPEE;
| | 60IE; IBOI; UBTHlIiri; LIU;
1 | B1BS1BESI: SnCOBT; BOLYSDEIOg;
I | EBOSPBOSBS: 8V9IDI«R: SC» IDIOT;
I [ 2HEIX1M; SIITEl; TIB: TOBGSIEI;
I | HIC; SMITE R1ZMOS: HDOSTBIll
1 | Enrrs; SBEITEBS; TiLinaitu
r i
1
a) lot gir«n a) 0.01 * or - 0.01 1 at Bales
bj Rot glf«t tg/g (w«t vt) | t) Faailas
b) 0.02 + or - 0.02 I
"3/9 C*et vt) 1 Ftoi a qrcuF of 61 aatopsiea.
1 fcienslc a«Ucal •zaainatiaiw. Japaa.
I S«l«s, Man ag» «0. S rr. Tcaales,
I aaaa aga 37.4 yr.
I HtCE ELIRERIS; 10TOPSIBS; JIP1I;
I itiBini; usEiic; cjsHioa: cosiiT;
| CEEC9II4; COPPBBJ 1801; HBtCOBI;
1 iinaa: aiGiisitjB; uicansE;
1 lOEltm; iiiiROH: scuDioa:
I KlIBCTBi TIIHIDE; TUlDlna; IIVC;
I CC1B; MOBIBE: ill ft; KIOIETS;
| CII!Bt"«.: CltEBEU-OH; BE11I; 809CIES:
I tttctMS: SPtlBI; IOIGS; lOBTl;
I RITUS; COIPUlTIf! ITILUITICHS; SIX;
I fCICISIC RIIICIIE
1-
BZFTBEVCE



lakava, R.
Sazafci-Tasvaoto, H.
ftaano« K.
Tcrai. 1.
1980
accaircf of
EaTlronaeotal aealtk
J5(1):36-«













Braaeff D.
lordberg, G.
Matet, P.O.
1980
Science of tie Total
EDTlronaent 16:13-35


















Tnkava* B.
Sazaki-Iasaaoto, S.
laaaOf K.
Tecai, B.
1990
lrcfclr«s of
ZBTlroiiB«Btal Baaltb
3 (1):3«-4«













































tsJ
to
































(itrt tiGE)

-------
HtO-36-0
itl 121.75, » (30 C. BP 1«3S C, TP 1 aa 89 at «8< C,  10  u  Bg  at 960
                                                                                      (COITIUBD)
man

35«
•aieteaa

















3566
Spleea
















ZirOSVH BOOTB






































lUlITXCal
BZTICD
II


















11

















•man
OF CUES
a) C
b) 3

















aj 9
b) 3
















sues

a) lot give*
b) lot given

















a) lot give*
b) lot give*
















BE1I

a) 0.01 * or - 0.02
ag/g (vet vt)
b) 0.01 » or - 0.01
ag/g (vat vt)















a) 0.03 » or - 0.08
ag/g (vet vt)
b) 0.01 « or - 0.01
ag/g (vet vt)














etltUL XBTOIB1TXOI

a) lalaa
t) reaalea

ftoa a groan ol 61 aotopaiea.
forensic nodical ezaainatioaa, Japan.
Rales, aeaa aga ao.e jr. Taaalaa.
aaaa age 37.1 vr.

IBICI E1EBEB1S: aOTOPSISS; J1P1I;
•maim: iBsiiic; CISBXVB; COBU.T;
cBiosiua; COPIIB; 1101; BIBCDBI:
1ICCTI; BlGIESinB; BlieillSS:
toEiDiia: iniBOR; SCIIDIOM;
snmii; Tiiiiioi; wiiDioa: ziic;
601D: BBOBIBS: 1ITIB; KIDI1TS;
CIBIBS55; CIBEBCUOB; B11B1; BOSO.BS;
EIBC1I1S; SPlEllj LOBSS; ICBTi;
BITltS; COBPUITITI ITlLVmOIS; SEX:
FCBliSIC BlOICin
a) Bales
t) rcaalaa

fcoa a group of (1 aatopaiea.
focaasie aaalcal ezaaiaatioaa, Japan.
Bales, *eaa aga ao.6 re. Faaalea,
acaa age 37.* TE.
1B1CB ILBBIBU: 1CTOP3IES: J»1B:
ItSIIVIl; IBSIIIC: ClDBtOI; COBUT;
CIIOBIVR: CCEPE1; I BOB; SEBCUBT;
XIDIOB; B16IZSXVB; B1I61IISE;
BVBIDIIffl; 1BIIHOBT; SC1BDZOB;
SILBII1!; TITIBIOI: TlUOIOBi IMC;
eciB; iBOBXit; IITEB.- siniirs:
ciinivi: CMDEILOB: IEIII; HBSCIBS;
piicins; sttni; itiiesi IOBTI;
•ITILS; COBMB1TIVE ETILOITIOIS ; SEX;
ICIBISIC BZEICXBI
BBIEtEICB

Tnkava, I.
Suaki-Yasuoto, R.
laano. K.
Terai. B.
1980
Irchivea of
Environmental Health
35(1):3«-«a











Takava, B.
Suzaki-TasuBOto. B.
aaaao, K.
Terai, a.
1980
Irehivea of
Enrlroaaental Health
35(1):3«-aa










                                                                                                                                                                                             U)

-------
   ixeclor 1260
   11096-82-5
   IUCT rosaou OIKIOII OB aiDCTiiaxi»
ussoe
3567
Blood.
nbola

















1
1
1
1
I
ElfOSUBE MOT


















1
t
1
1
1
1
immcii
RBTBOD
CC-EC






















1
IOHBI8
OF C1SBS
a) 36
bj «



















1
1
1
1
SHOE
a) lot applicable
b) lot detected























I IEII
a) 8 ng/g
D) lot detected























GtllBlI. IirOSBmTIOl
>1 1019 Ca»l residents, 1 positire
sinple
B) volunteers
Bean of positive siiplss. Llnlt of
•casareient, 4.4 «g/g
Claselr latched, slnltaneous control
tuples «er« not provided foe
analysis along with those fros the 36
love Canal area residents saipled.
licking leaaingfnl control ot
literature data relative to tie
significance of the lav residues
faand la th« field saiples analyzed.
BO definite conclusions can l« dravn
fro* toe results reported.
lesideits of lew rork. controls.
eiploree* of the Enrironaantal
Protection Igencr anS aiirersity
ttidenta, north Carolina.
Ill 10 K: IOITH CISCtlll! BLOOD;
KaSntraZII BET BOOS; CUlOSItl OKUZC
tcttatns; CHLOBOBiiziiiS;
HflCnOICEEREir; POlICBLOBIHilED
EICBHTIS; POPU11TIOJ EIPOSVII

imsEicz
Bristol, O.I.
1980
EM-MO/1 -90-036, »0
pp.





















Irsenic
TMO-38-2
1C
«tl 74.921«, » 817 c at 28 atn, BP «13 c (Biblines),  TF  1 nn Eg at 380 c.  10 nn  Bg at MO C
N5
1 TISSUE
1
1
1
I j«e
1 tort*
1
1
1
f
1
1










Mood









I EIPOSBBK BOOT
1
1
1
1
1
1
1
1
1
1





















: i iinniciL
1 StTtm


ri




I
I
I
I









Coloriietrr









I IOSBSS
1 Of USES
I
1
1 2
1
















1









B1BSI



•oge detected

|
1














lot applicable








(IBtl
Bill | Gllllal IIFOBBaTICI
I

|
•one detected | Bales
1
I Tros a gro«p of tt autopsies.
1 forensic sedlcal exasinatioss, Japan.
j Hales, sean age 40.6 yr. resales.
f seas age 37.4 rr.
1
| It ICt cllRIItS; IROFSRS; JIPII;
I lIOBIfM; 1F5ZIZC; C1DJHTB; COBILT;
1 cnonra; COPPEP; 1101; BEBCOST;
1 I IBIS!; giciisna: KaieuzsE:
1 loeiBra; union; scinioi;
f SE1EIIVB: TIIUIOB; nUDIBB; Zinc:
I SCID; Bionit; LITEB; EIDIEIS;
| CIIEBB91: CIHBEIUB; BEIBT; SDSCIES;
| tllCIEaS; SF1EEI; L»CS; 1C«TI;
I amis; CO»FIHTITE ETiioitieis: SEX;
I ICHIStC IttlCIlE
1
1.3 ag/g ( Ceath liTolvisg as. Tiss« speclseos
1 lilt ted 10 SCH casat by prior
1 astoeties.
I
1 ICITB cuotiii: IHTOKI-S: ctBujts:
I errii FOISOIIIG; BLOOD; BOIESJ BBIII;
1 Bill; UTtt; msctBSt sni; »aILS;
I BtimSSltt lETBOSS; BR1LS; TOlEtSlC
\ ciitcm
1

BETEBEBCE



Tekana. B.
Saz«kl-Tass,soto, B.
Isaio, It.
Terai, s.
1980
Ircnires of
En*ixonsental Bealth
35|1):)6-*4










BcBay, l.J.
Bldsoi, B.P.
BolitKj, V.S.
1979
Jonrittl oC Inalrtlcal
Toxicology 3:222-223






-------
•rseilc
7MO-3I-2
If
lt» 74.9216,
             Bt 817 C «t 28 ats. H- 613 C  (sebUMs).  TP 1 aa B« at 380 C, 10 is 89 »t ««0 C
                                                                                       (COR»HED)
«SSOI

3570
BOM









3S71
Brala


















3ST2
trail









3573
••it

















meson Mtni






























































iiunxcai
BIT 10t
Color! aetry










I*



















Coloriaetry





























•mm
or cms
5






























2





























BUGS

0.1-2.0 ug/g










a) lone detected
b) so»e detected
c) BOM detected
d) < or - 1.3 119/9 (net
«t)















1.0-2.0 ag/g





























mi

1.3 ag/g










a) lone detected
b) lace detected
c) Rone detected
4) 0.31 » or - 0.5»
«g/« t««t »t)















1.S ag/g





























GEIIUt IIFOBIaTXOI

teatks iavoliing as. lorsals. 0.1
tad 0.2* toy? (secondary raferaace) .
Tii»< specinns Halted in soie
cam by prior autopsies.

11 eikvaed tcdlea baried 2 «k-91 jr.
ICITB cHoiin; tno?siss: CIDITEIS;
eiTlt NISOIIRG; BLOOD; BOISS; EE1I»;
mi; Litrn; TOSCLE3; »ILS: SKU:
iiisvinni BIT BODS: IRILS; FOBEISIC
(IBKIII
a) Hales* cerebral* 13 subjects
k) Vesales, cerebrva, 5 sabjects
c> Rales, cerebellne. 11 aabjects
d) feiales. cerebell.ua. T labjects

fcoa a vcoap of 61 autopsies.
forensic aedical ezaaiBatioas, Japan.
Hales, aeaa aae 40.6 yr. resales.
M«B aqe 37.* yr.
tBICt ILBHtlTS; 1BTOP3IIS; J»P11;
lIOHIin; 1BSEIIC; C1DBIOB; COB1LT:
CBlCHIOl: COPPBE; IBOl; BESCOBT;
IBCIDB: aiGiisiua: IMGHISE:
tiEiDioK: iniROBi: SCMDXDH:
SUKim: TITUIDR; 7HIDIOB; ZIHC;
GCID; BBOBIII; 1ITE1; KIDIETS;
CIBBBBOl; CEBEBEtlOB; BUST; HO SCI. IS:
E1ICRE1S; SntXt; IDIOS; ICBTl;
BITIIS; CO'PIBiTITZ ETlLDiTIOIS; SEX;
KlflSIC BEDICXBE
faaths larolvinq Is. Tissue
iieelsens llaited Is aoae cases by
prior aatopsies.

11 eihased bodies bocied 2 ttk-97 TC.

BCPTI citoiiBi: imopsus: CIDMEBS;
DITIL POISOIIISi BLCOD; BOIES; EB1II;
BUB: llfEB; HOSCIES; SKI I; MIIS;
BB1SOBS1SI1 BETBODS; 1ET11S; FOBSISIC
BtCICII!
ftviev. 2» repreoeitatiTC
Fce-asalTsis treataeats ace
tabelatel. Ihe feasibilitf of a
kclistlc, no-«asli policy for hale
analysis Is eatlised and supported.
BEVIE*; TBtCE I1IIERS; Bill;
IBSTSUII; BElSHBElin SETBODS;
tfllLS; PBOTIIMS; COSPiBlTITI
itiinTiois; iineiioB: HTXHOII:
1ISEBXC; BUIDB; BSOSIBE; C1DBIIB:
cucioii: CBICBXIE; CBROHXOH: COEILI;
CCPPIB; 61ILIOB; GEBBinOHs GOLD;
ICDI1E; IBOl; LlaTBllVB: IE1D;
iieiEsiOR; iiieiiESE; sracnsT;
CCmDEIOH; HCKEL; IBOSPBOBDS;
toiissius; BOBiaiati; SELEIXIH;
SIHCOI: SII1EB; SODXOB; STBCITIDB;
SOLPOB: Til; TXltlXDtl; TOI6S1EI;
IIIC: TIBCOIIOB
BIfllEICE

HcBay, I.J.
Badsoo. S.P.
Baling, T.8.
1979
Jaarnel of analytical
Toxicology 3:222-223





Tukava. fi.
suznki-Tasaaoto. a.
&aano. K.
Terai. H.
1990
IrchiTes of
EnTiconsental Bealth
35(1): 36-4*












IcBay, l.J.
Radso*. H.P.
Boliag, T.B.
1979
Journal of Analytical
Toxicology 3:222-223





Cbittlebocosgh. G.
1980
Science of the Total
Eniiroasent U: 53-75















                                                                                       (HIT PtSZ)

-------
IM0-38-2
if
lt» 7*.921C. IT 817 c at 28 atm, BP *13 C (aabllaea). « 1 » Ig «t 380 C. 10 aa Si *t («0 c


HSSBI
3S7»
«»ir
3575
I«lc
ixposms wot

laatttiox
laaalatioa
1
1
3:16
Stir
amnmi
1ZTBOD
ColoriMtrr
u
r
•VMB>
or cisas
3
*
1
1
Mies
a) lot applicable
1) tot applicable
e) lot applicable
A) lot applicable
•) lot applicable
a) 10.8-76.1 ppa
b) 8,26-11.7 pp>
c) 3.33-K.O J>P«
t) 8.6-63.1 ppa
•) 4.22-12.7 ppa
f) 5.61-38.5 ppa

mi i sunn itrciBitioi i BsreiCTCj
1 1
1 1
1 1
a) C.O 119/4 1 •> <*•* •• ««tr 1 BcSay. l.J.
b) 9.0 «j/« 1 M «*•» 2' »e«lp aalr 1 Hodaon, 8.F.
c) 2T «g/g I c> Caw t, »calp aalr - proilaal I soling. T.S.
tj 10 «j/j I J) CIM 3, acalp balr - U«tal | 197*
«| IS «j/7 I «) Can 3, >aal« 1 Jaanal ot analrtleal
| tmtas livalTtnq >«, T!MM t Taxlcologi 3:222-223
1 *;«eiMm* liilt«4 la IOM caaa* bi 1
1 prior aitocila*. »
1 11 «a«a*d tedl«« 6«ri«d 2 «k-»7 re. 1
i tens citoim; tnorsitss cunmss i
I ittu raisoine; HOOD: BOIISJ BSU»: i
1 Bill: lilts; susciIS; sell: mis; 1
I iiastniHSit iRioas; BETU.S: roiasic i
i ncicni i
i t
1 1
a) lot siren I a) rtoa acaa, steel bconz« >crk«n I claf. J.S.
b) lot gi»«a j tl fcei lead, otMr norkcrs it I sale, I.
cl lot glTea | factory 1 cross, J. p.
dj (at girea 1 c| rrm a«ad, «te»l tcoaie rcrlters at I 1977
e) Hot flT«a 1 ctfcct factories I Journal of tbe SocietT
f) Rot oiren | if mm patlc area, steal broaia 1 of Occupational
I >ctk*r> I MdlclB* 27:102-104
1 <) tmm pabic am. otaar «orkets at I
I tactoiT |
1 f) froa pabic acea, steal brcne 1
I wcikeri at other factories f
1 I
1 letters ID factory ihere arilae 1
f faetorlea, U.K. I
I iiiizd meaci: umrs; MT*I i
r ICIJOiriS; BllB; »I13; CORM9IHTE I
I IH1B1TI01S; IimiSTim HTClni; I
1 iisnic: cisi; HULTB nziBDs: i
| IHIDSItlH IIROSPEEIBS |
i r
t 1
I t r«»iei of «orld literatare ot tie I Jenkitt, D. ».
1 accanlatloa an* blooonceatratiaji of I 1979
I selected toclc tcacw »
-------
Iticiie
1MO-38-2
II
Itl 7«.921C. HP 817 c at 28 »t», BP 613 C (sabliaes). TP 1 •• Eg at 380 C.  10 ••  Rg at MO c
                                                                                      (COItliaSD)
1ISSBI

JS77
Mart

















3578
Md»«T

















3579
Iido«T




















iipososs BOUTS




























































aEURICal
HIT BOB
11

















11


















11





















itmen
or casss
a) 10
b) S

















a| 23
b| 3

















at 8
b> 9
cl 9



















UBSS

a) < Or • 1.* «g/g (««t
•*)
b) BOM detected
















a) < or - 1.7 eg/g (Mt
*t)
b) < or « 1.« ag/g (»et
rt)















a) 0.0030-0.01* ag/g
b) 0.0020-0.016 ig/g
c) 0.0020-0.052 ag/g
I«t vt


















mil

a) 0.1* * or - 0.«»
»g/g (««t rt|
b) Bone detected
















a) 0.1* * or - 0.43
ag/g («et »t)
b) 0.»7 t or - 0.81
ag/» <»et »t)















a) 0.00*0 ag/g
b) 0.0095 ag/g
e) 0.0038 ag/g
let «t
leiiaas

















esisui IIPOBIMIOI

a) lales
t) Faialvi

ttoa a groap of Cl aatopziaa.
Coranatc aedlcal exaaiaatioast Japa*.
I<1<«, aetn ag« *0.< IT. F«ul«s.
•cai aga 37.* jc.

nici miens: aoropsiss; JIPII:
itmiioR: iissiic; ciosioa; COBU.T;
ceioiim: CCPPSBI 1101 : RSICOIT;
iirxvi: 816IISIOR: BUGIIISI:
SD3IBIUJ; llHBOiT; SCllDlnB;
snsiiiH; UTiMioB; vinoioR: me:
GC1D; BBOBIII: UTEB; SIDIZIS;
CIBIBinS; ClBEBSUORi HS1BI; HUSCLSS;
limns: sptEE«: miss; IOBTI:
IIT1LS; COSJ1BHITE ETIIDITIOIS; SEX;
fCSHSIC BIOICIHS
•) Ralas
t) T«l«l«s

Troa a group of Cl aatopsies.
fcr*nalc medical •xaainatioos, Japan.
Balas, a«aa ag« »0. 6 yr. ?aaal«s.
iaaa age 37.* jt.

met nsBsns: aotopsisss JIPII;
iiinin: USCTICJ CIDHIDB; coaiu;
ctBOBim: coppiB: xioi; Hiicnsi:
IB tins j siciisiUB; nieiisss:
BdsiDiiia: iBiiROii: sciiDins:
SItSBI0H; TIIMTOB; T1MDXDR: IIIC;
6010; B10HIII; LITBB; HOISTS;
CIBtBBOI: CIBEBBUaH; HS1BT; IVSdBS:
fltCBElS: SPISII; IDBSS: 1CBT1:
IITILS; COBP1B1T1TI ETltOltlCIS; SIX;
ICIIBSIC iinciii
i) Costrolt
k) war liar qroap I
c) lortar gteap II

Caceaaei cafinery aad saelter
vcckars* ag«> 55—76 jcf expoaed to
taaTf aatala 1-3 decaaes. Tiae
betMea retiieaent anl death 0-1. S yr
ia graap I an! 2-19 It, qioaf II.
ceatrols, ages *3-72 yr, iko llni SO
ka froa tb« factory. Sweden.
SBCCIB; CIOITSBS; KIDBETS; IITSB:
UlSSi CORPliHItl 1T1101TIOBS:
IIDCSTH11 II6ISIS; RSISOSERIBT
SIIBODS: 1BTIBOII; IBSEBIC; C1DBIOB;
ClStdl: CBBCHIOR: COEltT; COPPBB:
COLD: IBOB; X1I1R1IOB: IBID;
B1B61BUI: SIBCUBT: HOITBDZBOB;
iiospioivs: BOBiDiua; SCIIDIOS:
EILZBIDB; SXIYiBi TIBj laBGSTSI;
tnc; HSttTl UZ1BDS; IIBBSTBIll
EIIITS; SREIIEBS: TStmiOl
ESnUBCS

lakava. H.
Saiaki-Tacaeoto, R.
taano, K.
Teral. R.
1*80
Irehives of
EBTlrooaentsl Health
35(1):36-«»











Yakava. H-
Soiakl-Iasaaoto. R.
laano. E.
Terai, B.
1*80
arcaivea of
BDTiroiaectal Healtk
35(1|:3<-*«











Brana, D.
Vordberg* 6.
Mater, P.O.
mo
Science of the Total
CnTlronaaat 16:13-35


















-------
manic
74*0-18-2
a*
att T*.921C. «P 8IT C at 28  ata, » 613 C (artliaex) . TP  1 aa  If *t  380 c,  10 » B« «t **« C
                                                                                       (CORIIITED)

IISSffB
3560
LlMr
3!»f
Ilmt
BZF031BI SOWS

1
immClL
IRBOD
(1
11
(
1
1 3S82 f Colorlaetrr
1 U»er 1
( I
i r
101 em
or ctse
«> IS
b| 8
t| 8
b) 9
c) 10
8
t
1
BMOE U1I 1 EIKU1 IirtJtBlTIOB I SttttXICt
1 1
a> < or - 3.3 ag/g (mt al «. » + or - 0.»S I •) Bal« I Takava, 8.
rt) aa/» (vet «t| 1 It ?«••!•» t S»«W.-raanaota, 9.
») COM tetceted b) ROM *etect«d I 1 *nao. !.
1 rcoi i Troap at SI Mtapai**, I T«r»i, 1.
1 fomdc Mileal «x**ln«tioBs> Japan. I HBO
1 Bil«i, •••• aq« «0.6 rr. r«al», 1 irchires of
1 nu *v> 3^'* rr- 1 ZDTlcg»eBtal Jtalth
1 ( 35<1)i3«-«»
I «ICE taettrs; tmotsitst jwti; i
J liealOTI; IISHIC; CIDnVI; COSU.T: 1
i cnonoi: oo>m: IBO»S BSKOEI: i
I i»iva; sioMsitja; BUGIIBSI; i
i tviigiim: I«TUO»T; sctmim; i
I sniim: Timrtw; nuozvi; z»c: i
I sen; Btoaiii; IITEB; KIOIETS; i
i ciiuan: cnnriLOB; IBUT: SOSO.BS: (
1 Micsus! SPIHI; IDKJS: tont: I
I srms: coapiiinn iruomoTS; six: i
| KinSIC VEDICtK 1
> i
*> 0.0019-0.013 •«/«
fe| t.0030-C.(»J >g/4
C) 0.0020-0.0050 04/9
let lit
2-SS ig/a
1 1
a) 0.0030 09/9 1 «l co.troJs r Sraa*. 0.
b) 0.0085 ay/g r t) larkec fccan I 1 tortbarg, 6.
c) 0.0**0 «j/g | c) forkar grcop II 1 lestM, S.O.
rat «t I 1 W80
Hediaiu f X«c«as«d r«£in*ry and *a«lt«c I Science of tfce fotal
| «ort«n, a««* 55-76 fr, aipoced to 1 tn¥lcoo«ent 16:13-35
I «g«x 1J-7J TC, iia llnd SO (
I ti fcea tie laetarr. Svaaen. 1
1 1
1 5«lt!«; cm»E8S; KioiRSi lirfs: I
1 tnes: COBPISKITI miuiiois; i
| IJMSTBIU BIGIHB; B!lSti!Bt»T I
f HttOOS; IRUOir; USZVIC; ODHBB; I
cisiai: cBBoeidd; COULT: COPPH.- I
coit; iso«: unBHns: uio: i
FJIGIIISB: mean; BotiBDUm: i
taaspvnvs; BOSIDWB: sciinra; i
smiiaii; sitfre: TI»: Ttrissrjs; I
ZIIC; g»HB BaZIEOS; IHDttStEIll |
TllltS; SRItTEBS; 1XUQHV8 1
1
13.6 09/9 tcath* i»»ol»ioq it. taimtlt, 0. OS 1 BcBay, l.o.
aid 0.2* 04/4 (aecoataiT referance). I Badaoa, P.P.
Ilane speclaeaa Uaitel la soie 1 Bolinq, r.B.
c»e* br prlcr aatoasiea. 1 1979
1 Joicnal of mlrttcil
It eskaaad bcdiea bortel 2 rt-*7 rt. 1 Toxlcoloar 3:222-223
t
ICBia CIIOITU; 10TOPSIIS; C101TKS; I
sun POISOIIK3: aiooi; BO»S; miij i
Bill: UTtE; BUSC1ES; »»HS; sri>; 1
•tisninn IRBOKS: SHT*I.S: rosusrc i
ttnatt i
i
(KIT PIGI)
                                                                                                                                                                                           os

-------
linilc
7MO-38-2
II
»t» 7I.921C.
             BP 817  C at 28 ata.  tt  613 c  (snMiMS).  TP 1  •• 84 at  380  C,  10  a* Hg  at  atg  c
                                                                                     (COITHDBD)
1ISSTJE

3583
lung















358*
Ing




















3585
Raacle

















EIPOSOBB S001I



























































luinictt
BXTBOD
It
















Ik





















U


















IHBESS
OF CASES
a) 5
b) »















a) 9
b) 13
0 22



















a) 5
b) 10

















URGE

a) < or • 5.3 99/9 (wet
*t)
b) < or » 0.5* ag/g (wet
•t)













a) 0.0010-0.018 ag/g
b) 0.023-0.013 ng/g
c) 0.01»-0.21 ag/g
let "t


















a) < or » 0.50 ag/g (wet
"t)
b) < or * 0.85 ag/g (net
Wt)















Bill

a) 1.3 * or - 2.3
ug/g (wet wt)
b) 0. 1« » or - 0.27
ug/g (vet lit)













a) 0.0080 ag/g
b) 0,013 ag/g
c) 0.0*8 ag/g
Set *t
Bella as

















a) 0.10 « or - 0.22
ag/g (wet wt)
b) 0.09 « or - 0.27
vg/g (vet vt)















etIZBlI. IIFOXB1TIC1

a) Rales
I) Feaales

It am a groap of 61 aatapsles.
forensic nedieal examinations. Japan.
Bales, aean age «0.6 yr. Feaales,
aean age 37. a yr.
IB1CZ ZIZBI1TS: HJTOPSIBS; J1P1I;
noiiim: iBszvic: ctsaioa; COBH.T:
CHORUM; COfPSB.: IBO«; BEBCOBT;
IICIUB; BlGHlSIHB; RafGkBlSE;
IIIIIXDR; JITIBOIT; SCSIDIOB;
GCIO: BKORIIZ: IITZ8: KlfilZtS;
CIBZEKD!!; ClfEBZUOB: HE1BI; RDSCLBS:
fllCBZAS; SPlEZ-Ij 1QBGS; AGBTk;
BIT11S; COBP»B>TITS ZTUD1TIOI5; SBX;
ICBIISIC R1CICIIZ
«) Controls
t) Vorker gccqp I
c) Vorker grcnp IX

leceasai refinery and snelter
•crkers, ages 55-76 yr, exposes to
teavy aetals 1-3 decades. Tine
tctmea retireaent and death 0-1.5 yr
It group I and 2-19 yr, group II.
Ccntrols, ages 13-72 yr. vho lited 50
ka froa the factory. Sweden.
StZDZl; C1E1TZBS; KXDIZTS; 1ITEB;
imest coapiBiTiT! zTiigiiiois;
XlCISnill. BTGIEIE: BE1SDB1BUT
iHHons; imsovi; iismc: cmaioi;
cisnm; c HBO sio a ; CCBIIT; COPPII;
COII; IROI; HHIBIIOB; LEU;
E1161KS1: BtECOBY; B01TBDIIOB;
tlOSPBOBdSi BOBIBinB; SCUDIOT:
SKZIIM: SIITIP. ; ?II; TBiGSltM;
IHC: BZtlTB B1Z1SBS: IHIOSTBIil
PltHTS; SBZITEBS; TILLnBlOR
» Bales
t) resales

Iroa a groap of 61 autopsies.
forensic nedical exaalnations, Japan.
Bales, nean age «0.6 yr. Fcaales,
aean age 37. (1 yr.

isict SLHiiiS; inTO?sizs: JIPSI;
iicBi»oa: iKszmc; UDBIDB: COBU.T:
CBIOBiail; CCPPXB; IBOI; RZBCtBT;
IICIOR: »«isx0fl: BIIGIBZSZ:
BDBIBMl; 1IIIBOK; SCiUBIDB;
sttzixtii; TIUIIDR: TiiiDioa: znc;
GCID; B30BIII; IITIB; KIDSSTS;
CIBEBR31; C1EEBEXLOB; BJiBI; BOSC1BS;
PlICKIS; SPIZZI; LDBGS; 10B11;
BIT«LS: C09P1MTITZ BTlLDtllCBS: SEX;
fCIZISIC BECICI"!
BZFEBEBC5

Takava. H.
Saznki-Iasaioto, a.
leano* K.
Terai. 9.
1*80
archives of
iBTiconnental Bealth
( ): »«









Brane, D.
•ordberg. G.
•ester, P.O.
1980
Science of the Total
Environaeat 16:13-35
















Yakava, n.
SvznU-Tasaaoto, a.
laano, 1C.
Terai, S.
1930
irchires of
XnTlronnental Health
35(1):36-«»











(KIT PIG!)
                                                                                                                                                                                          IS3
                                                                                                                                                                                          VD

-------
Itsenic
m0-38-2
Ai
Its 71.9216. IP BIT C at 28 at.. BP  613 C (sublines).  TP 1 an Bg at 380 c, 10 •• 89 at 440 C
                                                                                       (C01TIIDBD)
TISSUE

3586
Bnscle












3587
Hall















3588
Bail




















BXPO30BE BO01B















Ingestlon
Inhalation





































ABA1TTXCAL
8ETBOD
Colociaetry













u





































BUBBBB
OF CASES
5













9





































BAHGE

0.8-5-0 ug/g













a) 15.0-188.0 ppi
b) 0.97-6.00 ppn
c) 6.45-53.3 ppn
d) 10.8-60.9 ppn
e) 2.98-4.81 ppa
f) 1.06-5.79 ppn

































(BEIT
BBaB

3. a ng/g













a) Bat given
b) Bat given
c) Hot given
d) Bot given
e) Bot given
fl Bot given






























•


PASE)
GEBIBAl IHFOBBATIOB

Eeaths Involving Is. Bornal, 0.43
ug/g (secondary xefeieDce) . tissue
steclseas United in sone eases by
prior aotopsles.

11 eihued bodies burled 2 «k-»7 vr.
Case adnitted to eaergency roon «itb
gastritis died 1 day later after
x«eoning cyatotic and Incoherent.
ICBTR C1BOUBA; IIROPSIBS; C1DȴEBS;
BITU POISOIIB6; B100D; BOBBS; EE»IB;
BIIB; iiTEB; aoscus; SRTB; i»ns;
mSOBESBST BBTHOOS; RBTA1S; T01EBSIC
BIDICH?
_
a) Fron linq«rs, steel bronze workers
fc) Icon fingers* otber workers at
factory
c) Fron lingers, steel bronse norkers
at other factories
1) Fron toes, steel bronze workers
e) fron toes, other workers at
factory
f) Fron toes, steel bronze vcrkers at
ether factories
Icrkers in factory where arslne
poisoning occurred and in other area
factories, O.K.
OBI1ED KIHGOCB; ADULTS; BBI1I
fOlSOBIBC; BUB; B1I1S; COBPtBlTIVE
IltltUTIOBS; IHDOSTBU1 HIGIIBB;
IBSZHIC; COST; BUITR B1ZABDS;
IIDOSTBIil limSPRBBES
.
1 review of world literature on the
accnnolation and bioconcentcatian of
selected toxic trace netals in ho wan
hair and nails and other nannalian
hair, far, nails, claws and hoofs.
latnlated ty geographic area.
subjects, sei. age, exposure
gradient, analyses in ppn. and
authority frcn over 100 references.
JFSICM IOSTBU.I1: ClBADl; CEHTI1L
IB1BICS; IOBOP8; KIDDIE EAST; BBS
1I1IABD; SOOTH ABEBICA; 500TBEAST
1SIA; OHJTED ICIHBDOB; OH IT ED ST1TSS;
BIIB: BAILS; BETIEW; ABTIBOBy;
IFSEBIC; EOBCB; CADIIDfl; CBBCBIOB;
CCBALT: COPPIB: IEAD; BSBCOBI;
BICKEl; SELIBIOH; TIB; TABAOIOI); AIB
ECIIOTIOB; ABIIAl POFOLATIOBS;
EICACCnaDIATIOB; BIOISDICITOBS; LAHD
ECIIOTIOB; POPDLATIOH EIPOSOEE; B4TBP
ICIIDTIOB; TBACV 31EHEBTS; BETAIS

BEFEBEBCE

IcBay, A.J.
Badson. B.P.
Doling, V.B.
1»79
Journal of Analytical
Tozicology 3:222-223








clay. J.E.
Dale, I.
Cross. J. D.
1977
Journal of the Society
of Occupational
Redlclne 27:102-104











Jenkins. D.W.
1979
EP1-600/H-79-049, 18«
PP-


















                                                                                                                                                                                             LO
                                                                                                                                                                                             o

-------
7MO-J8-2
It
Itl 74.9214.
             IP 817 C at 28 ata. >? 613 C (sablises) , TP  1 »•  tg  at 380  c.  10 •• Bg at MO C
                                                                                      (COBTI1DED)
TISSUE

3589
tancreas

















3590
Skia









3591
Spleea

















EIPOSUBS SOOTE

















































lllLTIICll
UTBOD
n


















Coloriaetry









11


















IflaBES
or cisss
a) 8
b) *

















4









a) 10
b) 6

















SIR6B

a) < or - 1.3 ag/g (mt

b) loae detected
















0.4-1.0 ag/g









a) < or - 0.5S ag/g (vet

b) lane detected
















BE1I

a) 0.28 * or - 0.48
ag/g (*et *t)
b) lose detected
















0.66 og/g









a) 0.07 + or - 0.18

b) loae detected
















Gtlliai IIFOiaiTIOl

a) Bales
t) resales

Icoa a groap of 61 autopsies.
forensic sedical exaaiaations. Japan.
Hales* seaa age 40.6 yr. resales.
aeaa age 37.4 yr.

TBICE ZLBBEHS; aUTOPSIZS; JftPIV;
IIOBIIUB; IBSEIIC: CiDBIOB; COB1LT;
CflOBIUB: COPFBB; IBOI; HEBCOBT;
litiuB: aaeiEsiai; aiieiisss;
IltlDIVH: alTIROR: SCIIDIOB;
s ii nua; TiHiioa: Taiaoiui; zitc;
ecu; BBOBIIB; LITIB: KIDIBTS;
C1IEBBHB; CIIEBI1LOB; IUBT; BUSCLIS;
titcftEiS; SMi«»: lines; ICBTI:
IRUS; COBCUHITE ETILUHOCS; SSI;
fCIEISIC IICICIIE
Ciaths iavoltiag as. lorsal 0.59
«g/g (secondary reference) . Tissae
speciaeas liaited in sone cases by
flior antotsies.

11 exhaled bodies boded 2 «k-97 yr.
ICIta C1B01II1; 1UTOPSIES: CIDtfESS;
BlTll POISOII1G; B1000; BOIES; BB»IW;
C1IS; lira; BOSC1ES; SKIB; I1IIS;
aiisnBtim HZTIODS: anaLS; FOBEISIC
itDicias
a) Rales
t) Feaales

Iroi a qcOBf of 61 autopsies.
forensic aedical eiaaiiatieu. Japan.
Bales, nean age 40.6 yr. resales.
scan age 37.4 yr.

Tiaci niazixs; mofsns: JJPAS;
iimnna: USEIIC; cinaiaa: cosui;
CIICRIOR: CCEPEB; IB01; REBCISI;
liriOH; RIGIESIVB; ItlSaiESE;
iiBiomi: niiRoiy; scaroioB;
SZIEIID9; TIiatlOR; flUDIOB: ZIIC;
eett; Bsoaiii: IIVEB; KIBBZTS;
cisiBtan; CZIEBSUOR; IE1IT; ansciES;
EllCSttS; SflEEl: LDieS; 10BU;
BIT IIS; COBPaBlTITE IT»10«IOIS; SZI;
ZCBZSSIC BZtlCIIX
BZRBEICI

Takava, B.
sazaki-Tasaaoto. a.
inaao. S.
Terai. B.
1980
archives of
Eavironaeatal Health
3S(1):3«-4*











RcBay. a.J.
Hudson, I.;.
Boliag, T.E.
1979
Joaraal of analytical
Toxicology 3:222-223





T«ka«a. R.
Sazaki-Tasasoto, Hi
asaao. K.
Terai, a.
1980
archives of
ZiTironsental Bealth
35(1):3«-aa











                                                                                        IIEIT

-------
Irscnie
7M9-38-2
la
lt» 74.9216, HP 817 C at 28 at., BP  613  C (subliaes), TP 1 >• Bg at 380 C, 10 mm Bg at  MO C
                                                                                       (COITIIOZ9)


















IISSOI

3592
Brine













EIPOSOB! BOOH
















1
minion
OTBCD
















j

IOHBZH
OF C1SSS


















1

tuet reii etizsiL IIFOIBITIOI

a) lot glttm a) 0.8 ag/g •) 9 ratal etildne, inarganic 19
b) lot givca ereatlaina t> 1* cklldm ILiiiq < 1 ka froa
c) lot 9iT«« b) 2.2 ag/g . 2.5 ka froa aaalter.
f) 5 ag/g creatinina tetal Is
I q) 7 ag/g creatinine f) 21 riral bora, total Is
1 Mdlans 9) 22 riral girls, total Is
c)-g) estiiatatf froa graph
Seaool-aga enlldran living naar Pb
sialtar in Ealgiaa. Controls fron

IlieilftSl; C.DBI08; USIIIC; 1SSZIIC
CBS1IIC COiPCOIDS; CBI1DBBI;
iiDosmn. iisosrszsts: SRZUZBS;
tlTUS; BIOOC; ni»; B1LGIOH;
fcpuiiTio iiPosnBi: iniu isiis;
| UIE1B 1RZ1S
1 1
3593 US 1 30 a) 7«-93» ng/1 a) 3«7. 0 ag/1 I a) Iiposad icrkers, 1G-11S technique
1 Urine I 1 bj 91-9S3 og/1 b) 368.8 ug/1 t) Biposad wcrkers, ET-115 technique
| lie) «.»-23. 9 ng/1 e) U.5 09/1 e) Controls, 1G-11S technique
| | d) 6.5-42.5 ng/1 d) 18.66 ag/1 «) Controls. ET-llS technique
III e) 6.9-25.6 «g/l e) 14.73 ug/1 «) Baaitarrnnean sorters, 1G-11S
| | | f) 36-1180 og/1 f) 382.6 09/1 t€Ckniq««
I I g) 15.5-113.1 ug/1 arkars excoscd ta Is203 and S
centrols. 10 Hedit«rra»aans, 10
Klglaa, totb possiblr •zposed to
inorganic Is bat diffarant lisk
ccnsasption. Data arailabla for
velsntaars and attasptad saicidas.

EHSlm; HE HE; COSP1HTIYI
iTiiDiTiois; nismmi HEIBOOS;
IBSnlC; IBSIIIC OI61IIC COaPOOIDS;
tuts; iiDosttlu puras: IIRBU
(IT1BC1ISB

SEfEBEHCE

Backet, j.p.
Foals, B.
laawarra, B.
Braaax, P.
Claars-Tkoraaa, !.
lafontaina, 1.
Verdarn, G.
1980
Invironseatal xasaareb
22:95-108












ncket, J.P.
laanarrs, B.
eels, B.
980
ateraational Irckivas
f Occupational and
nvironsantal Haalth
6:11-29



















-------
U»lM
778»-»2-1
II-B3
Bl 77.93.  » -117 C, B* -«2.S C
TISSUE
359*
Mir











BIPOSOBZ BOVTZ
InhllltiOn












iiiLrricii
RETROD













IORBZB
or CISBS
«












11KI
•) 39-216 ppa
b) 22-107 Hi











HZ1R
a) 107.3 ppa
b) 18.3 ppl











GEBisiL iirosBancR
•) Iftar 9 flays, loot sagiant
b| >it«r 19 days. 0-1 cm Ito» root

50-51 yc old sailor*.

»«»«r, Matacsa, naasaa, toiitinq.
diarrhaa, abdoainal pain.

BfBoqlobinaria, iatravascular
haiolysls. aarroa leprcssien.
ttioibocTterania. reaal failure.
ptiipliaral utoropatky-
ustmc; BUI; occnpi-ioiii HIUBDS
SEiEincz
slUlnson. s.P.
RcHnih, P.
Borsloy, S.
Tobba. R.
le»ls, 8.
Thooli. 1.
Mnterton. H.
Parsons, V.
Vllllaas. B.
1975
British Radical Journal
3(S983):559-5«3

 Irsifta oiide,
 Irslalc acid.
 C2-B7-1S-O2
 Bl 137.99. RI 200 C
                      - (9 CI)
                               (8 CI)
1ISSU!
3595
aria*











BltOSOBS BOOT I













aiumcii
BFTBCD













IOHBZS
or cisss
a) 9
b) 1»











tlBSt
a) lot gi»«n
b) lot gi»en











SE»«
a) 9.2 ag/g
croatinine
b) 11.2 09/9
cr«atlniae









S1I!B»L mOBHlTICI
a) Bncal ehlUrea
b) chiHren near sa«lter

Sekool-aije ehildraa liTinq »«ar tts
ciclter in Belqiua. Control* froa
meal aad arban araas.

R1I6IKSZ; CIE8I05; »SmC; 1RSEHIC
GfSirtC COITCTODS: CHI19RII;
IBDDSTBItl IHOSPBSS1S; SBI1TZBS;
BITtIS: BtOOC; UBIIS; BILGIBB;
ICIOL1TIOB IITOSORB; »DS»1 1BZ1S;
DIEII 1BI1S
BirZISBCI
Bucket, J.P.
Eoels, B.
Laanrys, B.
Brnaax. t.
ciMTs-Thoraaa , r.
lafontaina, a.
Terdnrn, 6.
1980
ZnTironaeatal Research
22:95-108



                                                                                                                                                                                        UJ
                                                                                                                                                                                        u>
 1tbastos
 1332-21-t
 IIICT coiposinoi amo*B OB OBIZTZBRMZD
nssm
3596
Gastric
liqola






BIPOSOB! BOITE









HI1LTTICH
BITBOD
Bicroscopy








BVBBSB
or cisss
13








S1BGI
0-2500 ferraqluoas
todies/20 il






(BEXT
BE1B
Hot 9iTen







?1SE)
GZIIBtl IBrOBBlTIOB


33-72 rr olds nit! 1-50 yr
occapatianal axposora

ISBISTOS; OCCUPlTIOItL H.Z1FDS;
IUBSS; ISDOS1BHI 1TSOSPBZBIS; DOST;
II>BCB

lErZBEECI
Biqnon, J.
Sebasties, ?.
Bonchaoz, G.
Boanaad, G.
197*
IBSZBR 29:205-218




-------
ItbeStOS
1332-21-*
IUCT coBfosmoB nno» 01
                                                                              (COBfttDZD)


























IISSOB



3S97
Gastric
llqaid











3598
Intestlae
EXfOS«n BOOM

















lagestlos



1IUYIIC1L
BETBCD


Biereseopv













IB

I0BBEB I1ICI Bill | CHIllt IirOlBllICl
or CISBS i
i

a) 0-158/20 nl a) lot given I a) lorkers hiadllaq raw asbestos
b) 0-»/20 al b) lot given I t) lorkers aaat factoring aabestos
c) 0-3/20 si c) lot given j [rodacts
I e) lorkers exposed to sized
1 iadostrial dgsts
1
1 33-M vr olds, »ith varinos disease
| occapatioaally exposed to asbestos.
1
| JStlSTOS; OCCOP1TI011L B1Z1BOS;
1 iciss: occnpiTiont oisusis:
I 1CTOPSKS; IIDOStlllL 1TBOSFITEIIS:
1 IQSI; nilCf
1
a) 21 a) not gives a) 150.0110 (!-5) I a) Controls
b) 32 bl lot given fibers/a I b) lesidents wlta long tern, bigb
b) 1«.3i10
-------
libestos
1332-21-*
IHCT coBposmoi omoiM ct OIDITHHIKD
txssoi

3600
larynx

























3601
liver












3602
mag








3«03
HBO






n*OS01J BOOT!

Inhalation

























Ingestion




























iiunicai
BETBC8
n
licroscepy

























n












HI








Bicroscopy






BDBBEB
or cists
2

























a) 20
b) 32












1








13






fllGI

a) lot applicable
b) lot applicable

























a) let gives
b) lot given












a)
1.4x10(1*7} -3.3x10 (E»71
fibera/g
b)
2. 7x10 (E+7) -6.5x10 (E+7)
fibers/g
Dry »t




lot deternined-200,000
ferruginous bodies/en cs






Hal

a) 590 fibers/eg
b) 3600 fibers/ig
Dry vt
























a) 153. 5110 (!-5)
fibers/g
b) 32. «1 10 (1-5)
fibers/9
Ish »t









a) 2.1x10(1*7)
fibers/9
b) 3.9x10(1*7)
fibers/g
3FT Vt






Hot given






6HI11L IIPOS81TIOI

a) Patieat 1. Fiber eea> length 2.»
a, Man Planter 0.08 a. Bate
ctiT'Otile thu aiphlbole fibers, lo
femgieaoc todies
l» Patiemt 2. Fiber Bean length 3. «
i. Bean lianeter 0.1* n. Bore
aapiiaole tkan chrysotile fibers
lorsal tissue.
fatleat 1. age SI yr. Exposure
tetceen aqes 13-15 Tr in welding
factory and tetveen ages 20-10 Tr as
electric arc Holder. Patient 2,
EBoker, aqe 51 yr. HeaTy exposure in
asbestos ceaeat plaetv pre-Vorld Var
2.
EneBsoeoBiosis. bronchitis. Benign
polyp on vocal cord (Patient 1) ,
sqoasoes cell caiciaoaa of larynx
llatieet 2) .
long opacities, costopkrenic angle
obliteration, plevral »all thickened.
FIHCt; ItDITS; CIS! HISTOBI1S;
IIDOSTIIll DISBISIS; M10PLJSBS;
CCCtlflTIOIll DISE1SES;
BHD10COBIOSIS; IHISS; 1TBPB BOOZS;
Eioiccninimoi: nsras; IIBH»TIO«:
1SEISTOS
a) Controls
b) Residents «ith long tern, high
level exposare troe drinking
centeniiated «ater
Chrysotile fibers
latopsies
52-S9 yr old resideats near taconite
riocessiag plant, Binaesota. 17-77 yr
eld controls. Minnesota and Texas.
B11IZSOT1; HUS: 10TOPSIXS:
iiiiSTiiis: urn: LOIGS; DSIMKHG
IITIB; IKtlDSIBIlI SBISSIOSS;
I1DOSTRIH FCIIDTI01; S1TIB
tCIintlOI; 15BBSIOS
a) inalyzel at Dniversity of Cardiff
t) Analyzed by laboratory in Paris
Earencaysa ftoa case of pleura 1
scsothelioia

lOlISS; ISEZSTOS; IE07L1SBS;
CCBFIIITITI ETllOaTIOIS; BK1SUBEREH
BIIBODS; FBItCB



33-72 yr olds «ith 1-50 yr
occapationl exposare

ISBtSTOS; OCCOP»TIO»ll HlZiBDS;
10I6S; IIDOSIBIal ITBOSPflEBES: COST;
ItlKt
(BUT P»Gl)
SIFEBEICK

Birsch, a.
Bignon, J.
Sebastien, p.
Candichet, a.
1979
CBIST 76:697-699





















Carter, S.I.
Taylor, ».?.
1980
Environnental Be search
21:85-93









Sebastien, P.
Billon, n.J.
Janson, X.
Bonnand, fl.
Bignon, J.
1978
archives des Maladies
Prafessionnelles, de
(ledicine dn Travail et
de Secorite Socials
(Paris) 39(»-5):229-2»8
Biqnon, J.
Sebastien, p.
Honchaax, G.
Btibnaad, G.
197*
IISEHB 29:205-218




-------
Ifbestos
1332-21-4
IIACT COBPOSmOl niKSOJI OB BISZTE8BIBBB
1ISSDE JMOSOBS SODTB AIAITTICAL lOaBSB IAIGE | BEAI | CBIMI1 IIFOB8ATIOB I BMBBBBCJ
BSTHOB 0? CASES 1 1 |
1 1
3604 IB 1 1.5-3x10(1*6) ferruginous
long bodies/cc
1
1
1
3605 Bicroscopy a) 200,000-700,000
lung fibers/cc
b) 85-135,000 fibers/cc
1
1
1
1
I I
1 1
3606 1 I Sicroscopy 5 «4- 7,840 asbestos bodyyg
lung 1 1 1 (vet vt)
1 1 1
1 1 1
III 1
III 1
II 1 II
II 1 II
11 1 II
II 1 II
II 1 II
II 1 II
II 1 II
III II I
lot given I Intopsy saterial | Sebastien, P.
1 1 Janrand, B.C.
I Occnpationally exposed «6 yr old vith 1 Bonnaad, G.
I flenral nesotheliona. | Gonl, J.
1 I Signon, J.
| ASBESTOS; OCCOPATIOIA1 B1ZABDS; 1 1973
I 10IGS; AOTOPSIBS; BEOPIASBS; FBAKE I Archives des Baladies
1 | Professiognelles. de
1 t Hedecine du Travail et
1 1 de securite Sociale
1 1 {Paris) 34(6) :335-344
1 1
a) lot given 1 i) (orkers handling rav asbestos
b) lot given I r) (orkers nanufacturlng nsbestos
I (toduets
1
1 33-16 yr olds, vith various diseases
I occupationally exposed to asbestos.
| ASBESTOS; OCCDPATXOIAL BAZABBS:
I IDIGS; OCCOPATIOIal DISEASES:
I IBTOPSIES; HDOSTBIAl ATBOSPBEBBS;
I COST; FBAICE
1
1
lot given I Averages of upper and lover lobes, «
I or - 1 SO. Autopsies.
1
1 3 forser asbestos pipe insulation
1 vcrkers and 2 patients vith
1 asbestosls, lung cancer and pleura 1
I aesothelioaa. Ages 48-73 yr.
1
| ACTCPSIES; CCCUPATTO1L HAZAIDS;
1 IIOPIASHS; DISEASES: ASBESTOS; I TIKIS;
| IICTIT
1
III II 1 1
1 3607 | 1 Bicroscopy 1 1 a) 1-20 ferruginous 1 a) lot given I a) 41 eases
1 lung II II bodies/cu a 1 b) Dot given I r) 38 cases
1 1 1 1 | b) 21-100 ferruginous I c) lot given I c) 18 cases
II 1 II bodies/co • 1 d) lot given I 4) 3 cases
II 1 lie) 101-1000 rerrugiaous I 1 lo significant correlation vith sex
III 1 bodies/cu a 1 | or occupation. * of cases vith
II 1 Id) >1000 ferruginous 1 1 21-100 bodies/cu a increased after
III 1 bodies/cu s 1 1 age 60. • of cases vith highest
III 1 1 density decreased after age SO.
1 1 1 24. 7« of cases vith highest density
1 1 1 lived in Paris.
1
Autopsies, 13-91 rr olds, rural and
urban areas, France.
lelatlonship vith lung cancer eannot
r« accurately analyzed because 9M
vere snokers.
TlllCt: 1COIISCEITS; ADULTS; AGt;
AUTOPSIES; nopiASBS: IHIGS:
ASBESTOS; ATBOSPRni: BU11B HI! AIDS;
1IBA1ATICI
1
1 Chatel. A.
1 Blgnoa, F.
1 Sebastieo. p.
1 ftlrsch, A.
, 1 Bignon, J.
1 Bader, J.-p.
1 Chretien, J.
1 1978
I 2:459-464
1
1
1
1 Soggli. T.I.
1 Greenberg, S.D.
1 Bclarty, J. I.
1 Burst, G. A.
1 Spivey, C.G.
1 Bieger, I.B.
1 1980
j Archives of
1 otolaryngology
1 106:533-535
Bignon, J.
Goni, J.
Bonnaud, G.
Jauraad, H.c.
Dufour, G.
Pinchon, B.C.
1970
Enviroasental Research
3:430-442
(HIT PAG1)

-------
Itbe*t03
1332-21-*
IIICT couosrnoi irinofi as OICZTEEHXIED
iissdl

3608
lang











3609
lung















3«10
long






3E11
Loag












IIPOSDIE iOUTf

lageatlon











Inhalation















Inhalation







Inhalation













*»LT1ICU
SBTHCO
EH











EH
Hicroscopy























EH













WO«BU
or cis 33
a] 20
b] 32











1















9







a) 22
b| 22
O 22
d) 12
e) B
fl 1*








(USE

a) not given
h) lot givea










	
a) lot applicable
b) lot applicable















1000-10 f!*61 ferruginous
bodies per en ci






a) lot giT
b) lot giT
c) Sot giT
d) lot giT
e) lot giT
f) lot giT








IE11

a) 570.6110(8-5)
Cibers/g
b) 11«3. 7110(1-5)
tlbers/g
ish wt









a) 46 ferruginous
bodles/ag
b) 3500 fibers/ag
Dry »t














•ot given







a) 3.7 » or - 1.8
fibers/ng iast
b) a. s * or - 2.5
Eibers/ng dost
_S) SO * oc - 81
fibers/ng dnst
I) 171 » or - 201
fibers/Kg dust
e) 322 .or - 351
Cibers/ng list
() »55 * or - 502
fibers/ng dust


GEimL IIPOBHUIOI

a) Controls
t) lesidents with long tern, high
level expoiin froa drinking
coataaiaated water
CtrvsoHle fiber*
1 1 tops lea
S;-8« jr oia residents near tacoaite
rcocessiag claat. linnesota. 17-77 11
eld controls, linnesota and Texaa.
•XIIESOIa; TIUS: IDIOPSIES;
IlttSTUtS: UT»; tDIGS: OBIVKIie
Itini; ISDUSTKIII BBI5SIOIS;
IICDSTSIil fClLOTIOl; 11TEE
IOIIOTI01: 1SBESTOS
liter aean length 2.8 a. Bean
diaaeter 0.13 a. Hore asphibole thaa
chcisotile fibers
tulaomary parenchvaa staples.
51 vr old patient. Exposure between
age: 13-15 vr in welding factory aad
tetweva ages 20-40 vr as electric arc
*il4er.
Paemocoaiosis, bronchitis. Beaiga
tcltp on Total cord.
long opacities, costophreaic aagle
cfcliteratioa, pleural wall thickeaed.
rtllCE; ICOIIS; USE HISTORIES:
IIOOSTBIH DISUSES; IIOPLIS8S;
CCCOTJTIOlll DISUSES;
fiioiocaiiosis: imrcs; LTIPB VODES:
EioiccointiTio": FIBIIS; ifBiniioi;
JSEISTOS
tata correlated well with ember of
fibers in spotaa.

labestos wocters. teao. age S4 vc.

1C1ICE; ID011S; IESPI1ATOBI
SICSETIOI: IIDU51BHL HTGIEBE:
ISEESIOS: OCCOP4TIOSH. HaZlBCS
a) loraal tissue
t) Spoataneeac Maathellona
c) Occipatioal aesothelioaa
d) isbestosle with aesothelioaa
e) tsbestoai! with bronchial
carcinopa
ft labestosis

OccapationallT exposed workers.
Cersanv

6ISB1IT: lOTOPStES; I»DtJSTBI»L
CISEISH: iniSS; tSBESlOS; flBEIS;
J1BIHTIOM; CCCOP1TIOIII. BiZlEOS
BEFEHEIC1

Carter, B*E.
Tavlor, i.f.
1980
Envlronaeatal B« search
21:85-93









Hirsch, 1.
Eigaon, J.
Sebastien, P.
Gaadicbet, I.
CBSSt 76;«97-699













BigaOB, J.
Sebastien, P.
Jaurand, fl. C.
He*. B.
197*
Eavlronaeatal Bealth
Perspectives 9:155-160

Triedrichs, K.K.
Otto, B.
1981
aaericaB Industrial
Hygiene Issociatioa
Journal 42(2)3150-156








(HIT Pl«)

-------
Asbestos
1332-21-*
met COIPOSIXIOI onion* OB BBBETEBSIIED
                                                                                   (COITIIUED)
TISSUE



3612
inng












1
1
1
1
1
1
3613 |
i £rspi> i
1 node |
1 1
1 1
1 1
1
1

1
1
1
1
1
1
1
1
1
1
1

1 1
I

361*
tespirato
rr
secretion




















1 EIPOSniE BORE AIAIRICAL I08EEB IAIGE IEAI I Gllim IlfOllATIOl 1 IEFESEICE
t HBTHOD OF CASES 1 I
1 1 1
1 II
Inhalation Hicroscopy 21 a) < 0.1-370X10(1*6) a) «3.27X10(E*6) | a) Dncoated fibers, death fron I Dorgan, A.
fibers/g fibers/g | nesothelial tnnors | Holies, A.
b) 3.a-11SOOX10(E*3) b) 1783.7«X10(E*3) I t) Coated fleers, death fros I 1980
1 fibers/j fibers/g 1 lesothelial tutors | British Journal of
1 fibers/g I fibers/g I cancer | 37:25-32
I fibers/g I fibers/g I cancer |
1 e) < 0.1-2. 1X10 (E*6) 1 e) 0.«SX10(E*6) | e) Oncoated fibers, non-cancer deaths I
1 fibers/g fibers/g I f) Coated fibers, non-cancer deaths 1
1 f) 0-210X10(1*3) fibers/g f) 28.93X10 (E*3) I less than 1* of coated fibers "era < I
1 Dry (t fibers/g 1 10 on long. 10* exceeded 80 an. I
1 • Dry »t I I
I lecropsies, 19-88 yr olds. Cancer 1
I cases occnpationallr exposed. Onited I
| Ulngdon. I
1 1
| | ASBESTOS: IOIGS; CABCIIOGEI; |
| | CCBMMTIU ITllOATIOIS: OIITED 1
| | KIIGDCH; OCCOPITIOI »L S1Z1BDS |
II II
1 III
Inhalation 1 EH 1 a) lot applicable a) 0.7 ferraginons | Filer nean length 3.3 o, nean I Birsch, A. |
1 Bicroscopy 1) lot applicable bodies/sg I dianeter 0.15 u. (tore anpbibole than I Bignon, J.
I b) 6, (00 fibers/ng I chrysotile fibers I Sebastien, P.
I Dry »t j lediastinal lysph nodes. I Gaudichet, A.
1 1 1 1979
1 1 1 51 rr old patient. Exposure betireen I CHEST 76:697-699
II II ages 13-15 yr in (elding factory and I
111 | | letween ages 20-«0 ji as electric arc 1
III 1 1 (elder. I
III 1 1
III I Eneanoconiosls, bronchitis. Benign I
III I FclrP OB *ocal cord. |
III 1 1
III I long opacities, costophrenic angle I
III 1 otli tented, plenral (all thickened. 1
1 1
1 1
1 1
1 1
1 1



Inhalation
.




ES



























a) 8
W 7
c) 5





















1








a) 20-2000 ferriginoas
bodies
b) 10-20 ferrsgiiKMs
bodies
c) 0-10 ferrnginons
bodies


















| FIAICE; 1EOITS; CASE BISTOBIES;
| IIDOSTBIII DISEASES: IEOPLASBS;
| CCCDPATIOI1I DISEASES:
1 tiBtrsocoiiosis: miss; LTBPB IODES;
| EIOACCOI10IATICI: FIBE5S; HB1LATIOI:
I A5EISTOS
t
1
a) lot gires I a) High risk exposure for 15 rr
b) lot given I t) Sod era te exposure for 25 jr
c! lot gives I c) Insignificant exposere for 28 re
I falnes for spntns
1
I Ccctpatlonallr exposed persons dth
I thoracic pathology related tc
j asbestos
1
1 Chronic bronchitis in 651 of 18
I stokers and the 2 ton-stokers.
1
I librosls, calcification of pleata.
1 cancer of the Inng or pi Mr a.
j lesions of snail airways foud in 80*
j at cases.
1
| ItAlCE: IICOSTIIAL DISEASES:
| KOtLaSlS; CCCIPATIOIA1 DISEASES:
| llSPItVTOtT SKIRIOIS; ASBESTOS;
1 inns: itAHB BIUIBS: IID
-------
libastos
1332-21-*
tun coBFosmoB imoii 01 oiminmio
                                                                                (CORIIHED)
1XSSBB
3«15
Basplrato
ry
secretion




3616
lesplrato
ry
secretlos



3617
Spatan



SXFOSBBS Milt
Inhalation




Inhalation







tinmen
BET8OD
ra
Bicrescopy




Bicroscopy



licroscopy



•BBIXB
OF C1SIS
2




•t <«
b) «2
c) 16



«» 13
b) 16
e) «5
d) 6«



Hies
a) let applicable
b) lot applicable
c) lot applicable




a) 2-10 ferragiaoas
bodies (n)
b) 2-300 FI
c) 3-1500 FB



a) 0-1 85 0 ferrsgiaoas
bodies
b) lot git ta
c) lot given
d) lot givea


(•JIT
BBIB
a) 20 ferraginoes
bodies/sasple
b| 3 ferzaglaoa*
bodies/Maple
c) 50.000
fiber s/saaple




a) 1 fecragiaoaa body
(FB)
b) 10 ra
c)' 100 IS



a) lot given
b) 100 ferragiaou
bodies
c) 10 fetcoginoas
bodies
d| 1 feccagiaou bolr


Plot)
GIIII1L IITOIIHIOI
a) latleat 1
b| Patieat 2
c) Patieat 2. Fiber aean lengtk 2.*
i, aeaa diasatet 0.10 a. loce
ektysotile taaa aapaibole (ibers
Talaea tor sfatas
fitieat 1, age 51 yr. Sxposare
tataeea agas 13-15 yt in neldiag
factory aad fcataeea ages 20-«0 yc as
electric arc (elder. Patieat 1,
itoker. age !• yr. Iea*y erposare ia
asbestos ceseat plant, pre-lorld Bar
2.
•aeasocoaiosis, broachitis. Beaiga
pclyp oa vocal coed (Patient 1) ,
iqnaaxiM cell carciaoaa of Itryai
(tatlent 2) .
laag opacities, costopkreaic aagle
ctllteratloa, pleeral «all tblcfcaaed.
isiBCB: IDVITS; CISB msTOKES:
IltHSntU CISUJBS; IBOPUSBS;
CCCOVITIOIll DISUSES;
(Koaocoiiosis; miss; LTIPB BODES;
!io»ccns
-------
   »tl«stos
   U32-21-*
   II1CT COBFOSItXOI
                             Ql U»BB«MI».HS
                                                                                          (C01TIT7EO)
IlSSffJ



3618
Spotaa









3CI»
snataa












Biposme sour




























iiiinieiL
BBTBOD


EB










licroaCOBT






HIIIBJB
OF CISES


1









— — — «__ „.













SJ»C!



lot given










	 iili 	 eiiuat urossi'ioi 	



300 ferruginous Occupational!? eiposed, lit. plenral
bodies/sasple sesotaelioia
1
I f( jc old (an
I
1 ISBtSTOS; CCCOVHtO.al EJ21SBS;
1 .rocs: AUTOPSIES; matusas; tsact
I
I
1
	 szrEtnci 	

i

Sehutlea, P.
Janraad, H«C.
Poaaand, G*
Gonir J.
Pignon, J.
1973
archives 4ea ealadies
Piofessiooaelles, de
Hedeeloe 4o TcaTail «t
de Secarite Sociale
1 (Paris] 3*{(]:33S-3«*
a) 29-523 f iberi/saapla 1 a) lot given I a) Sorters ta-dlig? rav asbestos chatel, 1.
b) 0-
-------
Enxaldebyde
100-52-7
C7-B«-0
Bl IOC.12, BI -26 C, BP 179 C. ?P 1 •• 19 at 26.2 C
irsstii

3621
Breatk










3622
Breatk












IXPOSVBB B001Z


























lEUTTICal
BETBOD
ec/BS











GC-BS












»D8B!S
OF CASES
9











54 (387
saaples)












BJIG1

lot detect ei-1. 5 ttg/ar











Bot given












Bill

0.2 ug/hr











0.513 ng/1
Geosetric












GBIEBal IirOSBITIOI

Ccipoiad froi unknown origin. Bo
ctker details given
cryogenic saspling teckique.

Bealtky nilltary and civilian
esployees, U.S. air Force School of
lerospace Bediclae. ages 23-47 yr. 3
tiokers.
EEIZEBES; CBtOBXEaTZB BTDBOC1BBOBS;
CBIOHIH oBcanc COSPODIDS;
CBLCBOBEBZZBIS; FLOOB.XBE COBPODIDS;
EBE1TB; I1CCBOLS; TBIIS; 1COLTS
Beaauced at 25 C and 760 ss Bg
2*. It occurrence
lexer and upper one-Slgaa Halts
0.15) and 1.6« ng/1

Bealtky. 18-35 yr old. nonsnoklng.
artan blacks and Caucasians.
Chicago, II. Rigidly controlled
eiperlnental conditions.
tBIITB: IICCEOLS; ItlXBOIS; aDOHS;
CElOBUiTID ETDBOCIBBOBS; TOLaTILE
CIG1BIC COBPCOTBS; BEallB BlZaBOS;
IIBIltTICB; BRIEOLISB; BETaBOLITES;
EOPOlaTIOB EIPOSOBI; OBB1B IBEaS
BEFEREBCE

Conkle, J.P.
Caap, B.J.
Belch. B.E.
1975
archives of
Environmental Health
30(2);290-295





Krotoszynski. B.K.
Bruneau. G.fl.
O'Heill. B.J.
1979
Journal of analytical
Toxicology 3:225-234








Einzena
71-»3-2
CC-B6
>< 78.11, n 5.S1 C, BP 80.093-80.09* C, TP  10  nn  Eg  at 26.1  C
IXSSOI

3(23
Breatk










362»
Breatk












ElPOSalX BOOTE



























llUTTXCal
BETRCD
SC/BS











SC-SS













IDHBEB
OF C1SES
8











54 (387
saBples)












Bliez

lot detectsd-250.0 ng/kr











Mot glren













BEal

40.8 U9/hc











».3 ng/1
Geonetzic












GE1IBI1 IIFOB11TIOI

Prevloas eipcsvre to conponnd. Vo
ether totallf given
Ctyogealc saipliag technique.

BealtkT illltary and civilian
eiployees, D.S. llr Force School of
leroapace ledlclne, ages 23-47 TC. 3
stokers.
tmtns: CBIOBIIITIO HTDBOC»BBO»S:
CeiOBXI! O«G»IC COHPOOSDS;
CE1CBOBEIZIIIS: PLOOBXI! CCBPOOIDS;
EPiHi: iicceois; TEIIS; mtn.'is
leasared at 25 C and 760 n* Bq
41.1* ocearrcnce
lever aid upper oae-Sigaa Halts 1.6
and 11.3 nq/1

BfaltbT, 18-35 rr old, nonsnlciag.
artan blacks and Caucasians.
Chicago, II. BigiaiT controlled
ctp«rlaeatal conditions.
IBEaTB; HCCBOtS; XILIIOXS; IDtriTS;
CELOBI11TED ETOBOdBSOIS; TOllTXIE
CEGIIIC CCBECTOBS: BSI1TB BH1EDS:
IIBlItTId: BETlEOlXSa; BETIBOLXTXS;
ICPOLITIOI EXPOSOBE; 3BBal >SEaS
EEFEBEBCE

Conkle, J.P.
canp, B.J.
Belch, B.E.
1975
arckives of
Environmental Health
30(21:290-295





Krotoszynski* B.K.
Brnnean, G. B. '
Ofleill, B.J.
1979
Journal of Analytical
Toxicology 3:225-234









-------
       Beaseae, cbloro-
       1C8-90-7
       CI-B5-C1
       »  112.58, BF -«S C, IP 131.7 C. TP 10 »
                                                  at  22.1 C
TISSUE
3«25
ireatk

EXPOSTSB BOOTI


i uitmcn
f ffXTBOD
OC/HS

ETFBZE8
OF C1SI5
8

BUGS
lot giTaa-a.OO? a«/fcr

BE1I
0.01)03 ig/hr

CEIEB1L IBFOSBaTICn
Ceapoaal fcoa aaJuton origla. to
ether detail* qlnn
Cryoaeatc aaapliag teekaiqae.
Bcaltkj eilttarr aad civilian
aaplorees, U.S. air Fore* School of
lerospace Bediciae, agea 23-«7 jr. 3
IIBtBBES; CBlOBtBlTtI BTDBOCUBOBS;
CnCBIBI OBG1BIC COBPOBBOS;
CELOEOBNKBES: FLBOillg COHPOHIDS:
CIB1TB; IICOEOIS; TBtlS; IDVtTS
BEPIEEBCI
Cookie, 3. P.
Caap, B.J.
felck, B.E.
1975
IrcklTes of
t»iniiaeital maltk
30 (2): 290-295

     Emma. «tk|l-
    CS-IIO
    Bt 1»(. 1«. Bf -94.97 C,  BP 136.25 C.  TP  10 •• Hfl at 25.9 C
    I  1ISSVS
                 sxtosmy tent t
                                                       OF C1SIS
                                                                                                                               entiu HFOSBITIOI
     3626
 I
 I lahalatlon

 I
 I
 I
I
  I
  I
  I
  I
  r
_i_
                                                    I  «

                                                    I
                                                    I
                                                    I
                                                   I
                                                   I
                                                   I
                                                  .1	
                                                                   0.50-0.80 a9/1
                                                                                              0.6925 a
-------
f*i**ie, aeiackloro-
C6-C1«
If 28*. 80. » 231 C.  tt 323*326 C, TF 1 •• Bg at 11*.* C
IISSVI

3C29
adipose








3630
adipose












3631
Blood
















niosntE Boott























lagestioi
labalation
Deraal















alllTTXCll
1EYIOD
ec








OC-BC





























main
or CASES
60








a| 22
b) 1*
cl C
d) 6
e) 6



























11KI

0.23-10.70 ppa








a) lot give«
b) lot given
c) lot given
d) lot given
e) lot given










a) 5-1121 ppb
b) 30-9)0 ppb
c) 3-600 ppb
d) 22-«67 ppb
e) lot given














Sglt

1.36 ppa








a) 0.2* » or - 0.09
•g/kg
b) 0.36 » or - 0.2*
ag/kg
c) 0.12 * or - 0.06
•gAg
d) 0.08 «or - 0.07
e) 0.09 4 or - 0.03
•g/kg






a) 310.7 * or - 287.7
PPb
b) 311.5 » or - 2*2.9
ppb
c) 159.9 t or - 1*2.7
PPb
d) 170.3 » or - 111.8
ppb
e) 0.1 * or - 0.6 ppb










Ctmil IIFOIBITIOI

Feripheral tidier fat. roatlve
pathological •xaaliatloas

Iges 6 IO-92 it. Belgian

BHBIBI; 10TOPSIES: IDIPOSE TISSUE;
tlOaCCOROllHOI: PESTICIDB3; DID:
IK; OBI; DIUOEII; HBPT1CB1CB
IPOIIDI; BIIICB10BOBZBIEI1; III CUE;
CBIOBIIB oiemc COBPOOIDS
,
•1 Ilderlr icn
b) BlderlT «enen
c) Toiiq I*B
) Bevborns
crlrenal tissae
176 survey.
•topsles frei 3 donor groipa.
v«rage ages 70 "vr. 2* yr. and 25-35
\, Oslo, lonaj.
ItltOSB TISSBE: BILK; COHPlilTIVB
IflLOiTIOIS; IOBIII: IDOItS;
iVTOFSIlS; IIW8O1I; CnOBIIlTED
BTBBOCISBOIS; IDT: PBSTICIDBS;
ICITCBtOBIIlTtO BIPIMYtS
a) SO exposed vorkers. 197*
b| *9 exposed corkers, 197S
c) *9 exposed vorkeri. 1976
dl «* exposed vorkers. 1977
e) ** controls. 1977
a)-d) aaalrzed by different
lafcoratories.

laplorees of a chlorinated solvents
plait in Ibcrillle parish. 11.
197*-1977. Controls worked In a
polyethylene prediction plant.
Be detected dif fereaces betveen
exposed and controls studied in 1977.
BIIICHIOBOBEHBB1: NI6ICIOIS; BLOOD;
IICDSTIIU. FLUTS; OCCOPITIOHL
iiziiES; let: siciiL STUDIES;
iiinsTiiii iTHospBnis: iionsniit
JICIEIB; COBPU1TITB EY1LU1TIOIS
BIFEBCTCI

Dejoaekheere, I.
Steirbait. 1.
Terstraeten, B.
Rips, I.E.
1978
Toxicological European
Research 2 (2): 93-98



Brevik, E.R,
Bjerk. J.B.
1»78
icta Fhariacologica at
Toxleologica
•3(1)8 59-63









Carrier, I.F.
•cCliians. C.D.
Bana-lloyd, 6.
1980
Joarnal of Toxicology
aid SivironMBtal
Bealth 6:367-377












(HIT fjtet) ' '"
                                                                                                                                                                                           OJ

-------
CcnzeM, aesacaloro-
ce-ci«
1< 28*. 80.  K  231 C, BP  323-32* C, »P 1 u tg at  11*.* C
























IISSO! BIMSOIB iOOTE UllTTICtl
B1TBCD

3632 00 K
Blood,
ibol*


















1
1
1
1
1
1
1 3f33
1 Bilk
1 1
1 1
1 1
1 1
1
|










GC-EC
SC/BS






1



363«
(Ilk


1
1
f
1
1
1









flTSBES
or cises

*) 35
b| «

























a







fUGS


a) 0.1-3 ng/g
b) 0.1-1 ng/g

























.6-17.1 ng/kg







1
1

I - - -
Bill | GBIrBII I»TOBB»TIO« 1 BKnBEXCX
I |
1 1
a) 0.6 ng/g | *> lore cannl reaidenta, 100T ( Bristol, B.I.
b) 0.3 ng/g 1 to«lti»e caarlea 1 lego
I b) Tolnateer*, 10M positive aaaples I IPI-600/1-80-036, 40
1 Halt at aeatoreaent, 0.011 eq/y | pp.
1 ClctelT aatctol, siaqltaaeoai control I
1 *a*Bl«< vere not pcovttod tor 1
1 i*aly*U along «lta those froa the 3* I
1 Icve Canal area residents aaapled. I
1 lacking aeacingf ol control ot I
1 llteratare data relative to tbe 1
1 ctgnifieaac* of the lo* r«»ldne» I
1 foand la tie field saaplea analrr»d, I
1 no definite conclnslons can be dran I
1 fro* tan reialta reported. (
1 1
1 I««ldents ot >•* lork. Controls, I
1 eaploye** ot the Zsvironaental 1
1 Protection Igeacr and oalveratltT 1
1 «tndeot». Berth Carolina. 1
1 1
t «!« TOSH: IOFTH CUOIIll: EICOD: 1
1 Btismnm Brrsons; CBIOBIBE OSGIIIC i
1 CCBfONBS; CBIOFOBBIIIIBS: 1
1 ItllCnOlOBtKEBI; POirCSLOSMJTIB 1
I HPBiiiis; pcpoiairoi Bifostjsr i
1 1
1 1
.9 «g/kg I Uctatiag aetbers 1 Sodrlc-Snit. R.
1 1 salt. -L.
\ 17-41 vr olds fro* Slavonia Province, 1 oil*, X.
1 Yugoslavia. I I960
1 1 Pesticides Honitoring
1 locosmn; uctalioi: Kin: i journal 1*(1>:l-2
1 iiotccmnKio* ; BBUI aa»s; i
1 CKCtlMTEC BTBBOC1EBOJS; C BIO 8MB I
( CEGMTC COHECTTSDS: CHIOJOBSIlrBtS; 1
1 tIE: DDT; BinCBIOBOCTC£OB»IBB: 1
1 HSTICIDIS 1
1 1
ec-BC I a) 14 aj *ot girt* a) 5.5 • or - 3.7 a) Oslo, large iadusrrialiled city 1 Brer Ik, E.a.
1 b) 11 b) (at girea no/kg t) Berqea. large iada»trialin>a city I Bjerk, O.B.
O 10 c) lot giren » 9.2 « or - 4.0 c) Barstad. saaller dtr vitb large I 1978
6J 9 &) Bot given ng/kg cbealcal/petrochealcal complex 1 act* PbarMcolo?lca et
c| 2. 7 + or - t.O d) Porsgrana, aoa-lBdastrielizod' 1 Toxlcolo?ica
ag/ltg flaking coasmity 1 *3(1|:59-«3
i) 3.2 « or - 1.2 U7« sarnv. Significant difference 1
ng/*g (f < fl.OSI tttveen saapllag *lte»: I
EC r gen > Oale > Barstad, PomgcuiB 1
t
looegian aether*, ages 25-28 ir. f
1 ICIP05I IISSBE; «n.K: COBPJSlTIfF I
I cmgiTiois; IOKIIT; tcans ; \
1 IttOPSIBS: BHBOIB; CBtOBHHED I
1 BUBOCtlEOBS; DM; PISTICIOIS: {
i i fcticaionmiD fiPBfins i
1 1 1 1

-------
It ami*, o-aickloro-  (8 CI)
E«I»M. 1.2-aickloro- (9 CI)
CC-B«-C12
S« U7.«, HP -17.5 C, Sf 1*0-183 C,  T*  1  «  Bg  »t 20.0 C
TISSUE

3«35
Btaath










BiniOBS BOOH












iiitnicii
BRIOD
8C-BS










•DBBM
OF CaSIS
» (387










IIICX

lot gl*«










1EII

2.* ng/1
Seoaetric










SEiitiL nrotamoi
	
Masnct at 2S C ana 760 a* Bg
13.91 oceimnc*
lovtc a*a «pp«r one-Sigsa Haiti 0.«3
aaa 13.5 ng/1
Kalthr, IB-IS TC old. aaaanktig,
attaa blacks ana Caucasians.
Chicago, II. Bigidll conttoll«d
.
Obi, 6.
1975
EBTironaantal Pollntioa
8:2««-274





-------
    Mama, p-ajckloro- (t cxt
    mm*. 1,1-M.cklora- f» «)
    1M-M-T
    ee-t«-ci2
    II 1*7.01, It S3 C.  W »7«.«  C,  Tf  10 M tg «t 5*.« C
TJS3BS

3S38
flood.
• boll






3639
BMatk











xuosm *om

Inkalatio*





















I uitmcu.
imoB
8C






1
I
IK- as












tmtst
or C»SB
c








M per
•UplM)











1MSI

•-16 »g/»l








•Ot 9iT«l












IUI

9.5 »g/«l








1J.« ««/i
e*a»t£ic











czitui inoiMtioi



IWltkf J

ll «t 2S C «»a 7<0 » M »t.« occ«ci:«c« tewr «»4 BFp»r aD*-sl4M licit* ».t lid J«.3 «?/l I«althr, 18-35 Tt oW. non*»oti«q. it tin blacka Md csteuikB*. Ckleago, n. Hflldly emtroUcd «ip«rlM>t«l condlticua. (I»T«; HCOtOU; IUIVOIS; IDU1TS; cnciiuiie miociiBois; »ot»rn.e CSSIPIC cowcnD5: IUITB miBos; HBJiiTici; maeoiisa; SITJKHITBS: FCCIIIIICK EITCSVn; OlUt *SU3 nnma Borit«, S. Oki, 6. 1475 z>Tiroi»«Bt«l Fellatio! 8l2«»-27» troto«T»ki< B.K. Era, S. S. O'KUJ, H.J. 1»7» Jooreal of Unljtictl loilcologj 3:225-23* t«MM. fntackloco- ce-»-ci5 » 250.3*. Bf 86 C, IP 277 C 1 IISSO! 1 • 1 1 3MO Bilk 1 iiFOsaii IOITTZ 1 « 1 I 1M1TTIC1I I BVTH00 t t i eoic t OC/TIS I I train i or c*si5 i i 1 6 1 1 1 | 1 11KI 1 1 1 0-3.4 «g/t-j 1 1 t ' 1 atti 2.0 ng/*j 1 Gtitiii nrotaiTioi 1 I tictttiiq ietk«t* 1J-»1 fr olds fro* SlaMiia (rotlic*. I*«o*l«ri«. TCCOSHTll; ItcIlTIOl; Silt; BJOICCOSOIITIOI; IDIU U»S; CKenntn mBoctiBois; cnoim cienic coatents; cnmoBiizsus: tti: on: nxicnoMcrcioMUit; fISTICIDIS Kninrcz Io


-------
ftate«e, peitacaloroiitro-
82-CI-8
C«-C1S-C-02
HI 2»S.«. BF »6 c, BF.328 C. It 0.013 •• Bg at 25 C

36*1
Blood,
•bole





















ElfOSOR BOOT!























1U1TTICU
BBTBOD
OC-EC






















miBEE
or cuss
a) 35
b) 11






















MICE
a) lot applicable
b) lot dttacted






















•Ell
a) 0.2 nj/g
b) lot detected






















CBIIBII IirOBBHIOI
-
a) Love Cagal reaideats, 3* (1)
tctitive
b) volonteeri
lean of positive saaples. Llalt of
aeasareaeat, 0.1S ag/g
Closely aatched. sinltaneoas central
saaplei vere not provided for
aaalTSis alaag *ith these free the 36
love Ctial area residents aaapled.
lacking seulngfnl control er
literature data relative te the
significance of the Ion residaes
feind in tbe field sanplos analyzed.
ao definite coaclvsloas can be drain
fios the resells reported.
Itsidents of lev York. Controls,
eaplovees of the Environmental
Iiateetiea leaner and wtlveralty
(tadents, lorta Carolina.
Ill YOHKs IOITB CUOlIIl; BLOOD;
ItlSgiNBII IETBODS: CB10BIIB OBGaRC
CCBFOniDS; CBLOBOBIIZSIES;
IIIICBlOlOBEnEIS: FOLICHlOllmBO
IltltlTLS; POPOL1TIOI SZCOSOBE
BEIXBEICE
Bristol, D.I.
1980
EPI-WO/1-BO-036. ao
pp.




















Baana*, propyl-
103-65-1
C4-I12
II 120.2. If -99.5 C. BP  139.2  C, TT  10 ••  H« at «3.»  C

36«2
Breath










IUOSHIH SOOT I











1HIITIC11
BBTBCn
	
0C/BS










•OIBES
or CISBS
a










tllSE
lot detect «d-6. 5 ag/hr










mi
1. 1 ag/hr









"
6IIII1L IIPOBB1TIO1
Ceafonad related to noraal
••tabolisn. lo other details given
CrTogeaic sanplinq tecbnigee.

Bealthy ailltarr and civilian
eiplovees, O.S. air Force School of
lerospace Hediclne, aaes 23-»7 vr. 3
aaokers.
EIlZEIfS; CBIOBII1TED RDIOC1BBCIS;
CIIOIIIE OIGHIC COIPODIDS;
cncMiNZBiis: rtnonii coipoms;
fltlTB; alCOBOlS; tBZIS; 1DH1TS
BEIESEICE
Coakle. J.P.
Canp, B.J.
nich, B.I.
1975
archives of
IiTironnental Health
30 (2): 290-295






-------
     IJSS1-13-7
     C9-B12
     » 130.2. » -2!.37 C, BP  576,1  C.  V* 100 •• Kg at 108.8 c
tissn
3««3
Cnatk










nfOSOBB BOOTS












iiUTTXcat
BMBOr
EC/IS











Btnuxi
or cuss
8











met
lot d«t«ct«4-9.3 ag/ar











nil
1.2 ag/bt











CZHMI nroBHiiar
Compound fiei aakaon origin. la
ctkct fetalla gi»«n
CXTogvilc aaipliag teebaiqw.

Maltkr •ilitwr a»J cirili.B
• •plor*«<, U.S. lit Fore* Sckool of
l«Mp«c« RcUclM, <9«s 23-«7 jr. 3
••okcrs.
Zfl»»S| CBtOIIMTZO BtOSOCIfiBOBSj
cnoim atcinc cocfomos;
C81O10BH2II1S; nocim caimnos;
tuiTi: ncoeoLS: THIS; loans
nnum
c«n>kl«, J.P.
C»*p, B*3.
»lch, B.I.
W75
»rclil»«« at
XmrlrauutU Mlltli
30 {2)1290-295





    l«0-«7-0
   C1-B5-I
   HI 103.1. IIP -12.8 C, BP 191 C,  11  1  M  84 l coaUtloaa.
I
| IBftTB: ilCCBOlS; H1IK113; JOOLT3;
| tnOHBlTIC (IDBOCtSBOIS: TOW Tin
I cismc coBFcmtis: BMITB ginms:
| KEUnlOB: BRaZOLISB: BEHPOLITIS;
1 pcftniTioi ttnsns: aisn »BIJS
•
tErnncx
Krotonyaaki. B. E.
Ecoaaav, 6. a.
O'Baill, B.J.
1979
Jaanal of analytical
Toxicology 3:225-23*










                                                                                                                                                                                               oo
£«»irl«aiB«  (8 CI)
e«ax*MMtaataiim  (9 cl)
1CO-W-9
C7-B9-B
ft 107.2, BP 18- C^ If 1 mm Bq at 29.0  C
X1SSVE
36«5
Bmth












SXCOSOB5 1OOTB














IBllTTlcal
HTBOO
OC-BS













or cisss
S» R8T
caapl^sl












Eire!
lot giT«a













BUI
-
0.007 ag/1
Scoavtlie











1
GEItBlt nroiBlTIOB
Kaaatad at 25 C met 760 aa Bq
12.94 oecarraae*
Ic««r aa8 tpj«t oaa-Sigaa lialta
C.0015 aad 0.0327 aa/1

Btaltky, 16-35 yr oU, aoaaaoliia.
«tttn blaeka aal caicasians.
Olcaqo, II. HigillT coDtrjll«4

-------
leryiitai
7«*0-*t-7
fc
Itl 9.01211, tl 1287 C. BP 2500 C. W 1 •• Hg at 1520 C, 10 aa Ig at 18(0 C
IXSSOI
3S«6
Blood

36*7
Oriae

IltOSOBI MOT!




lULTTICJl
BBTBOD
us

us

•01 BIB
or cisss
10

a) 2
b) 8

BIKE
lot given

a) lot givea
b) lot givea

BUI
1.0 * or - 0.% ng/g

a) 0.9 * or - 0.5
ag/g
b) » ng/g

61IIM1 IirciIlTIOl
Ceatrol valaes. Increase by factor
of * for eiposed groap.
1 persons nocking *-6 kc daily in
at«a vlth Bacl2 leakage aad 2
non-exposed controls. Federal
t«{iabllc ef Cersaay.
CHiiiT; EiocD: DBlii; BiBiuins;
miLS; eoiomioi iirosoFl; B»TS
a) Coatrola
k) Ixponfl gtovp. leak at * 4»T»«
•>ti«ate4 frea graph.
B«B «orki«g «-« br daily in area with
I«C12 l«akag« and aoa-«zpo8«d
ceitrols. federal Bepablie of
Scraaar.
GIB1JUT; BIOCD; DBIfE; BEBT1LIBB:
inns; popotiiioi ncosoBi: BUS
BIFIBZfCI
Stiaf«l. t.
Schnlxe, X.
Zornf n.
Tolg. S.
1980
irchiTes of Toxicology
•5:81-92

Stiefel. T.
Schulze. K.
lorn. B.
Tolg. 6.
1980
Archives of Toxicology
•5:81-92

ti;k«iTl  (8 en
l.l'-Blphwjl  (9 CI)
92-52-»
C12-B10
BI  151.2. tt 70 C, BP 255 C. TO  1  aa Bg  at  70.6 C
TISS1I
36*8
Breatk












BirOSUBB BOD1I













1HLTTIC11
SSTBOB
SC-BS












IOBCEB
or cisss
5» {387
aaaples)












»I6B
lot given












Bill
0.032 ng/1
Geometric












GUlBiL IIFOSa»TIO»
Icanred at 25 C and 760 aa Bg
2C.74 occacrenca
lever aad nppar one-Sigaa liaits
0.0096 aad 0.109 aoyi

Baaltkr, 18-35 TC old, nonsaokiaq.
artan blacks and Caucasians.
Chicago, II. Bigidly controlled
eipcrlaeatal conditions.
EBIJTB; UCCEOIS; IIIIIOIS; tDOITS;
CEICSIHIIEO BIDBOC1BB01S; fOLlTTLB
CBGinc coitcniDS; HIILTB Binsts;
IlBlltTIOl; «R>EOIISfl: BITiEOlITES:
tCPOUTIOH UPOSOBE; OBSiS »BE»S
EErilEBCE
Krotoszyoski, B.x.
Brnaeaa, G. B.
0«»eill, B.J.
1979
Journal of Analytical
Toxicology 3:225-23«








                                                                                                                                                                                             vD
 tiphenjl.  ciloro  (8  CI)
 I.l'-Biphenyl, chloro derits (9 CI)
 1336-36-3
 IIICT COSPOSITIOI DIKIOVI OS OIEnZBBIBZD
TISSDB
36«9
Idipose







BTPOSOR! SOOtZ









1U1TTIOI
HETBOD
GC/HS








BHBEZB
or cisss
16








ClIGB
1.6-3.2 ng/g (fat basis)







CE)
GZIIBaL IBTOBBITIOB


faaples frea hospitals and aedical
exaaiaer's office in Tokyo.

JltlB; «»IFOSE TISSUE; BLOOD:
CBICIOBIBZIIIS; PESTICIDES:
EcucBLoauniD EIPBIBTLS; IIHOSPHEBE

fEfEBBBCE
Borita, B.
Ohi, G.
1975
EnTironaental Foliation
8: 269- 27*





-------
Mphenyl, chloro (8 CI|
.I'-Blphenyl. cbloro aerivs (9 CII
336-36-3
UCT coBPosmoa OIIIOVB OB OBDETEBBIBED
(COBflBtTBD)
iissnt
3«5«
laipose










3651
adipose















3652
Idlpose









3653
Blood














BIPOS0HB BOD1B
























































aEaLTHCU
BETBOD











_
ec-Ec
















OC-SC










EC- EC















B03BBS
0? C43SS
a) 33
b) 1
c) 1









a) 22
b) 14
0 6
a) e
e) 6
O 36











2


























BlBSB
a) Bot given
b) Bot given
c) Bot given









a) Bot given
b) Bot given
e) Bot given
d| Bat given
e) Bot given











	
a) Dot given
b) Bot given









a) <0. 5-8 ppb
b) 1-22 ppb
c) 1-12 ppfc
a) 1-12 ppb
e) 1-18 ppb
f) 1-23 ppb










BEaB
a) 2.6 * or - 1.90
ppn
b) 3.2 ppn, fat basis
c) 4. 2 ppa, fat basis








a) 2.14 * or - 0.86
•o/kg
b) 1.65 « or - 0.83
•g/kg
O 0.92 » or - 0.38
ag/kg
I) 0.63 • or - 0.53
ng/kg
e) 0.90 » or - 0.42
•g/kg







a) 200 ppa
b) 600 ppn









a) 3.0 or - 1.5 ppb
b) 3. 5 or - 2.3 ppb
c) 3.8 or - 2.0 ppb
S) 3.7 or - 1.9 ppb
e) 3.3 or - 1.9 ppb
f) 3.1 or - 2.3 ppb










GBBtBll lEfOBslTIOB
a) Bospltal catlenta
b) 13 vr old resale «lth lasho
e) 46 vr old nale eitb chronic PCB
cottoning

Japan

IClICcTOBIBlTID BIPBIBYLS; DDT;
BIUCRlOIOCTCLOamEB; BLOOD PLaSBA;
Bionisas; Jipai; saSTBOifiBsnaii.
SISTBB: FISTICIDBS; UIPO5C IISSOB;
U»tB; KIDB1IS; OBEBTOB
a) HderlT nan
b) Ilderlr icnen
c) tonng aen
tf) Toong voien
e) Bevborns
lerlrenal tiesae
197C sarvev. Significant increase in
elderly conpared to 1969/70 survey.

letopsies frcn 3 donor groups.
average ages 70 vr, 24 vr, and 25-33
•k, olso, Borvay.
ICIPOSE IISSOE; BULK; COBPIB1TIIB
ITtlOITIOBS; BOBilT; ADtltS:
lOtOPSIBS: BEIBOBB; CBLOBIBATBD
B1CBOCIKBOBS; DDT: PESTICIDES;
ICllCBtOBIBIIID EIPBEBILS
a) Sanple 1
t> Sanple 2
Cose and origin onknovn
Eata also foi 6C/HS, identltying PCBs
(ran pentacbloroblpbenrl to
d«cachloroblchenTl, at loaat 1»
isosers and cl analogs

JCKOSE TISSOB; BEaSOBEBBn BBIBODS;
IOITCBLOEIB1IID EIPBBBILS;
eioiccoainnoB; POPOLITIOB EIPOSOBB
a) 1972. 129 sanples
b) 1973, 123 sanples
c) 1974. 117 sanples
0} 1975, 113 oaaples
e) 1976, 100 sanples
() 1977, 101 sanples
Concentrations highest in 1st parity
nctbers.

180-141 laetatlng voaen, 2 souths
after delivery. Besidents of Osaka
Icefeetnre, Japan, varied diets and
JIPIE; t»CI»TJOB; BLOOD: BIIK;
EioiccnanitiioB; PESTICIDES;
ECITCBIOBIBIICD BIPBBBnS; OBGtBIC
CEIOBItE COBCOHBDS
BETEBEBCE |
I
Inoae, 1.
kbe, s.
Takamatsn. a.
10*1. I.
Blkl, s.
fojlvmra. K.
1S75
raknoka Bodies I Joarnal
66(10:610-616



Brevik. E.B.
Bjerk, J.E.
197B
Icta Pnarucologica et
Toxicologlca
43(1) 159-63











Biros, f.J.
talker. I.e.
Itedberr, 1.
1970
Bulletin of
Znviromeatal
Coataniaation and
Toxicology 5 (4): 317-323



Takasblji, T.
vatanabe. I.
Knvabara, K.
Tosbida, S.
KayaDja, K.
Konlta, B.
1979
International archives
of Occopational and
Envlronaental Health
43s 1-15





(BEIT PlGE)

-------
fipheeyl, chioro (8 CI)
.I'-Bipkeayl. chioro derive (9 d)
33C-3C-3
HCI COBPOSITIOE OinOIB 01 OHITMRIHD
(COBTIBDZD)
jjjSjf - - — — -
36M
Blood








36SS
Blood










3«5«
Elood








3«57
Blood










3658
Blood.
plaaaa









IIFOSO1B BODXI




















Ingestion



















Ingestion









IBURICU
BETBOD
OC








ec










GC-BC








ec










ec









BVBBBI
or cisss
a) 17
b) 16








37










66








a) 2*
b) 15
e) 2
d) 37








a) 30
b) 18
0 11









BUM
a) <0. 2-12.8 ppb
b) 1.7-4.6 ppb








a) lot given
b) tot given
c) lot given
d) 1.25~« ppb
e) 1.8-0.* ppb







11-720 ppb








a) 3-26 ppb
b) 2-11 ppb
c) Bot applicable
d) 1-7 ppb








a) lot given
b) lot given
e) lot given









BE1I
a) 3. 8 + or - 3.6 ppb
b) 2.8 + or - 0.8 ppb








a) 3 ppb
b) ». 8 ppb
c) 2. 55 ppb
d) lot givea
e) lot givea







M ppb








a) 9 ppb
b) « ppb
c) 2 ppb
1) 3 ppb








a) 6.0 ppb
b) 10.8 ppb
c) 3.7 ppb









CBItllt IIFOTB1TIOB
•1 1 10-6 yr olds
t) Bothers of children
Children* s blood level varied »ltk
length of breast-feeding.

lesUents of Osaka, Japan. Bothers
eith no occa rational exposure to KB.

fClTCILOtlBltm BIPKEBTIS; BILK;
BIOOD; CRIltBEl; POODS; PESTICIDES;
JlVftl
a) Bothers. 8 so prcpaxtna. 1977
b) Bothers. » ao prepartaa. 1977
c) Bothers. ; so postpartoe, 1977
d) Breast-fed infants, birtk and 1
yr. rinal valne 1.7 ppb at 3 yr
O Bottle-fed Infants, birtk and 2
yc. riaal Talae 0.5 ppb at 3 yr
lalaes froa graphs, other data for
17 aornal pregnant eoaen. 20 infants.
tOlTCBLOSIUIIO EIPBEITIS: 1CTBOBI;
IIE6IMCT: JU1B; BIOOD: BILK:
11CTITIOB
latleats vita skin disease cansed by
rice oil contaninated vitk
highly-chlorinated PCBs. Tested 9
ic-1 yr after Intoxication.

laieaa

CItOBIBl OBG11TC COBPOOIDS; EIPHHTL
CCBPOOWDS; foOD COIT1BII1TIOI; CBII1;
Sill DISElSIS; BIOOD
a) Patients - gas ehroaatograa (GC)
patten peculiar to ynsho
b) Patients - GC pattern siailar to
a)
c) Patients - GC patten siailar to
d)
d) controls
significance of similarities not
dlccossed i> English abstract.
lasho patients, nornal controls
JiPii: eioot: BiPHEin cosronws:
fOITCHIOHllTID EIPBEITIS; POPOllTIO*
I1FOSOB!
a) lasho cbildrec
t) Bothers vho coasaaed
ECB-contaaiaated oil
c) Control children.

Exposed aothers. their offspring, and
eentrols la Japan.
Ciarrkea. physical dullness.
ationlnal pain.
fClTCBLOBIHTID EIPBEITLS; BIOOD
CIISBI: JIPII; rooo COITIBTIITIOI;
CBIIDltl
(HIT PIG!)
BETIBE1CE
Knvabara, K.
yakashiji. T.
latenebe, I.
Toshida. S.
Koyaaa, K.
tanita, I.
1979
Bnlletin of
Eavlroanental
Contanination and
Toxicology 21:*58-«62
Kodaaa, B.
Ota, H.
1980
Icchives of
Environaental Health
35(2):9S-100






Chen, P.B.
Gav, J.a.
Wong, c.K.
Chen. C.J.
1990
Bulletin of
Environaental
Contanination and
Toxicology 25:325-329

Basnda, T.
Kagava, B.
ShiaaaaEa, I.
Takada, B.
Karatsnne. B.
197«
raknoka Bedlcal Journal
65(1): 25-27





Jbe, s.
Zaone, y.
Takanatsn, B.
1975
nkaoka Bedical Joaraal
6*(10) -eos-609








-------
       lr  chloro (8 CI)
l.t'-BlphCBTl,  chloro derits (9 CI)
1336-36-3
      coBFosmoi vEinoni OB n»rmEBi»ED
                                                                                     (COITTIOED)

























TISSUE EIPOSIJBE SOOT I alalTIICll BtUIES B»GE HE1B GEBEB1L IBTOBHTIOB I EIIEBXfCI
BETHOD OJ C1SES 1
I
3659 GC a| 82 a) 1-7 ppb a) 3.0 * or - 1.3 ppb a) Controls 1 Takantao. B.
Blood, b) 15 b) 2-15 ppb b) 6.3 » or - 4.0 ppb b) PCB-polsoned patients | I none, I. •
Plasaa t Ibe, S.
EIPBIJH CCBfOUIDS; CB10BHI OBG1IIC I 197*
CCBPOOIDS: Eicon ; BLOOD PLISBI; JJPM I Foknoka nedical Journal
1 65(1):2S-31
1 1 1
1 1 1
3660 1 a) 33
Blood, 1 1 b) 19
alasaa 1 1 c) 30
1 1 d) 1
1 «) 1
1 ft 1



1
1 t
1 1
J
I
1
r
36«1 I BC a) 107
Blood. i b) 151
plasaa 1 c) 166
1 1 d) 192
1 1
1 1
III I
1 1 \
t t t
f 1
I 1
1 1
1
1
1
|
i
3662 1 1 OC
Blood, ( 1
(bole






3663
Blood,
•iole



3«6«
Kidney








































9C




















6








a) 11
b) 25




1










a) fat given a) 6. 1 * or - 3.52 a) Hospital patients | Inooe, T.
b) lot given ppb b) Znciated persona | ibe, 5.
c) Bot given b} S.4 + or - 4.26 e) (bn-enaciated persons | Tafeaiatsu, B.
d) Bot given ppb d) 24 yr old aile »ith aplastic | lofci, ».
e) Bot given c) 4.7 » or - 2.17 aoenia and stoach caacer , mid, s.
f) Bat given ppb e) 73 yr old nale with colon cancer I Fnjivara, It.
d) 92 ppb f) 13 yr old fenal* with Tnsfco I 1975
e) 230 ppb | rakuokn Beflical Journal
f) 5 ppb Japan | 66(10:610-616
EOITCraoBIIlTIB BIP8EBIISJ DDT; I
BEX1CBI080CTCLOHEHBI: 3LOOD PL1SH1; |
BIOPLISSS: JU1B; S1STBOIIIISTIML I
STSIEIf; PESTICIDES; 13IPOSE TISSUE; |
I If IB; KIDEET.S: OBSBTOB f
|
•
a] 0-20.6 pfb a) 0.3 ppb a) Baral blacks r Finklea, J.
b) 0-29.0 ppb b) 1.9 ppb b) Urban blacks | Priester, 1. 1.
c) 0-22*0 cpb c) 2.3 ppb c) Brbaa Caucasians | creason, J. P.
d) 0-16.6 FFb i) 3.1 ppb d) Bnral Caucasians | Banser, T.
1 Biaoers, T.
t | Orban ana rural residents of sc, t Banner, D.I.
1 Infants, children, adults, elderly. I 1972
1 1 Jnerican Journal o*
I SOUTH ClBOLIBl; IBDtTS; CBILDBEB; I Pabllc Bealth
I IKIal STUDIES: BLOOD PLaSBli 1 62 (5» : 6*5-651
| CCBP1SJTITB IT1L01TIOIS; ODD; DCZ; I
I CCT; CIJLDBIB; PESTICIDES; |
1 ECETCB1OBII1T1D EIPHEEILS: UB I
I iciiVTioB; rcoo coiriauiTioH: i



2.2-4.0 ng/nl








) 1-6 ppb
) 1-12 ppb




ot applicable










1 PESTICIDE BI5I9UES: POPDL1TICH )
I IIPOSOBE: BOIU IBEaS; OBB1B 1BI1S 1
1 1
2.9 ng/al I | gorlta, B.
1 1 Obi. 6.
1 Bealthy Japanese, aqes 21-35 yr. I 1*75
I I Environieatal To lint log
I JIEIl: 10IEOSI TISSII: BLOOD; I 6:269-274
| CBLCBOBEIZIBtS; PESTICIOZS; 1
I ECITCHLOBIR1TED BIPBEBHSJ ETBOSPBEBE I
t 1
1 1
a) 2. 8 « or - 1.5 ppb | i) controls | Takasatsu, a.
b) *. 8 » or - 2.9 ppb | b) ECB-poiscwl patients 1 Inane, I.
1 f Ibe, s.
1 EIPBIBTL OOBPOHEDS; CBLOBIBE OPSIITC | 1974
I CCIPODIOS; Biooc: BLOOD PLISBI; Ja?ll I Pokaaka Bedical Journal
1 | 65(1): 21-31
36 ppm (fat basis) I 34 yr old (ale with aplastic aneni* | Inone, T.
1 aid stoaacb cancer I Ibe, S.
1 I Takaaatso. R.
1 Japan | loki, f.
1 1 Biki, 5.
1 tCITCRlOIIIKID tIPBEJTLS: DDT; | Tu1l«ira. K.
| BIIaCBLOlOCTClOBnHI; BIOOC PLISBI; \ 1975
1 lIOfLtSsS: J»»; G»STBOI1TESTI«IL I rukaoka Heiical Journal
I £1J1»8; fSSTICIBSS: UIVOSS 11 S SOT; | SI (10s« W-616
t mis: nmis; OBHTUS \
1 >
                                                                                                                                                                                          Ul
                                                                                                                                                                                          ro

-------
Eipbenrl, ehloro (8 CI)
I.I'-Blpaeiyl,  eklaro derivs  (9 CI)
U3C-3C-3
tiici COIPOSITIOI imtxNi os
                                                                                   (CORII0ED1
HSSfll

3« 9





















a









MUSS

lot applicable









«) lot given
b) lot given
c) lot given
4) lot given






a) lot ilven
b) lot given
c) lot given
d) lot given





















<0.0*-0.1 ppl








inn
Hit

TO ppa, fat basis









a) 612.5 ppb
b) 680.0 ppb
c) «82,5 ppb
d) 5)0.0 ppb
Fat basis





a) 2» * or - 9 vg/kg
b) 2» » or - 9 ilf/tg
o) 29 » or - 8 ag/kg
fl) 19 * or - « 19/kf





















0.05 ppa








P1GE)
GIltUL IirOEBaTIOl

2« TE old tale «ith aplastle >•«•!&
tti stesaea cancec

J*p»

ICltCBLOSJiniD nPHCTTLS; BDT;
DiiiciLOBocictoEnaiE: BLOOI Piisaa;
izociisia; 4ipi«; O«SISOI»TISTIUI.
3TSIE5; PESTICIDIS; IDJSOSI HS3HJ;
tiTtB; Kitiiis; CHITHI!
i) 1 wntk
b) 2 laithl
c} 5 loathe
41 T untie
Uter pactnltlon i« 19T3. Estlcated
ftea qcapk.
lecul, pceqiant «ose> In Japan.
ECtTCILOIIIllfO EIPBWTIS; lIBBCBi;
CItCIllCT; JIP11; BtOOD; VOX'.
IICTITIOV
•> Oslo, Ittge iBdistrlillxci city
1) lerqea, large IndastrlallxeA city
c) latstal. JMllit cltr >ltk lar?«
ch«ilc«Vp«troclie»ical coatl«r
4) foraifrnnB, non'ln4astclallzea
(iailiq cotatnit;
1576 »act«7. si quit leant Increase (P
< O.OS) In Oilo, Bergen, and Barsta4
eaaplat e««pared to a 1969/70 s«Tey.
lemqlan aethers, ages 2S-2S yr.
ItlPOSB TISSUE; BHX; COHPIIITITE
IllLUlttOlS; IOBB1T: tBOtTS;
IOTCPSIBS; ItlBOBR: DOT; CEtCBISlTEB
ETESOClBSORS; PESTICIDES;
ECITCEI01II1TID miEITLS
t«Tin of bleloqical inpact of PCBs
en breast-fed infants and
r«coai«nattions far nrstnq nothers

J1P1I; IBNTS; IinnS; SKIi
I1SE1SES; RIIK; BtflCT;
ECtTBIOIIllTID BIPSIiTLS;
ECITCHtOIIIlItD BIPBMTLS;
EI01CCHBVl*IIO1l; nRE EETISDlRIS;
fCCE CORJBIIHIOf: TOOOS; HCTITIOH;
tCPQUTIOI IIPOSOE!
8iab«st 2 levels In boose* lies «ho
bad navec lived ostsiie Colcrada.

H-2« yz olds In 2 Colorado
eonniaUles vitn popolatlona of about
•5,000, prisarlly aqrlcaltacal, ligtt
irdnstcr.

CCLOB1BO: 1EI1TS; IULK;
EOIICB!.OB1«»T!D EIPHHTLS: KVOLHIOI
IIPOSV1E; BOIU HX»S
_

SEfEBEIC!

Inoae, T.
»be, s.
TakaMtsn, a.
aoki, ».
Riki, s.
rnjivar*. K.
1975
raknoka Radical Journal
66(10:610-616

Kodaaa, R*
Ota, R.
1980
Irchives of
EnvlcanneDtal Health
35(21:95-100




trevlk, I.H.
Bjeck, J.E.
1976
let a PnarMcologica at
Toxicologica
«3(1):59-«3









Biller, S.I.
Tinberg. L.
1977
Journal of Pediatrics
90 (3): 5 10-512






Savage, E.P.
Tessari, J.D.
Ralber?, 3.9.
Vheeler, H. v.
1973
Bulletin of
Environmental
ContHiaation and
Toiicology 9(«):222-22S


                                                                                                                                                                                        Ln
                                                                                                                                                                                        OJ

-------
ti;k«BTl. chloro (B CI)
1,1>-Bipk««Tl, chloro aarlTS (9 CI]
133S-36-3
tiler coiposmoi vinoi* OB OHSTIBRHSD



















TJSSII

3670
Bilk









3671
Rillc,
yhole


ZIPOSDE! SOUIB












Inaestioa



[
1
1IUTTICIL
HETBOD
GC










SC-IC

ICSBJS i Hies »"i
OF CUSS 1
1
1.057 a) tnce-S.100 ppa a| 1. «96 ppa
b) 0-< 1 ppa b) Rot airea
c) 1-< 2 ppa c) wot giTen
it 2-< 3 pp* 1» »ot 9i*e«
ej > 3 ppa I e| got giisn
Fat *t bacl* 1 rat »t basis
f
1
I
|
f
a) 0.01-0.10 ppa a) 0.032 * or - 0.019
b) lot gif«n ppa
eitmi i»ro«HTic»

a) Total. 1»77-117«
b) 27t it saiplaa
c) «9.5« of saaples
91 17. « at eaaples
ej 6. It of aaaples

Besideots of llcUoM

IICBIC1II; JDDHS; BlUt;
EOHCHl SIPBIHILS; IMIII
BIXIBES; I»DOSTBHl IB BIS
a) 1972. Ht saaples
bl 1973, 123 aaailes
c) lot «i«a bl 0.038 » or - 0.025 1 c) 19TI. tit saaFles
I dj 0.01-0.1* ppa ft* 1 A) "75. 113 saapl«s
| •) 0.01-0.10 ppm c) O.o»0 * or - 0.026 1 «) 1976, 100 samples
| t) 0.01-0. 2« ppa ppa 1 *1 1977, 101 saaples
1









1
t
3S72 | I a) 1 a] lot applicable
0 Kit «l I I b) 1 b} lot applicable

1




1
1 1
, I 	
i) 0.036 • or - 0.023 I !«»«!« kii?k«st In 1st parity aothers.
PP« 1
e| 0.033 * or - 0.017 I 100-141 lactatlag »oaeo. 2 aontks
ppa I after dellTery. Residents of Osaka
f) 0.039 * or - 0.02 I Prefecture, Japan, varied diets aal
ppa 1 CBTlroaaeotal coadltloas.
1
I JIF»: ticiinoi: BLOOD; HII.K:
1 tioiccniiJiiTic»: PISTICIDES;
| FCIICILOHIJITID EIBBHTLS; OS611IC
I CBIOBIIE cosponicts
|
a) 1»0 ppa (Cat 1 a) 73 ji old aal« rlth coloa caacec
BIKBEBCE

Sicklier, T.H.
Bcilliant, l.B.
copaland, fi.
tildea, t.
1981
taericaa Journal of
Public Bealtb
71(21:132-137



Takasbiji, T.
tatanabe, I.
Kvvabara, K.
Tosblda, s.
Korana, K.

















Ktmita, 1.
1979
International Ircaires
of Occupational and
EnTlronMntal Health
«3:1-1S





1
1 in
luone, I. **
basis) I b) <6 rr olJ sale »ith atoaach cancer Ibe, s.
b) >. 1 ppa (fat 1 Takaaatsu, I.
basis] 1 Japan lokl, ».
1 Rlkl, S.
1 FOIICBLOIIIIIID EIPBEITIS: Oil; Fo1i»sra, K.
1 BmcHtoiocTcioHHiiB: BIOOB PLISSI; 1975
1 HOPtlSIS; J1»I; GasnoinZSTIUL Fnkaoka Hedlcal Joaraal
1 STSTU; PESTICIDES; UIPOSZ TISSOJ; e6(10:610-C1«
I tiTra: IIDIIIS; OSEITUI
	 1 	

-------
Cocoa
7MO-I2-I
I
It! 10.11.  U 2200 C (approz), BP 2550 C, TP «.5SItO(E-S) atl «t  21*0 C,  1  u «« at 2664 C. 10 u Hg at 3030 C
1ISS1E
2C73
laic



















EitosTin IOCTB





















11U.TTIC1L
BETBCD





















BOBBER
or cuss





















mei





















»»i





















CEIEB1L IIFOlBaTIOB
1 revle* of world 11 tent arc OB tke
aeeiBBlatiei anl blocoacentratiOB of
aaleetei toxic trace aetala IB tuaa
laic aid aalli anl otaer aaaialiaa
kiir. ««r, aallB, cla»« and boots*
tabulated IT qoo^capUe ir«a.
iibjccts. svi. a««, exposure
fiall«at( a«lTa«s In ppi, and
aithorltr Icca over »80 rafcnaces.
iftict: tBSfitiia: CHID*; craTiu
IIIKCl; EOROIB; SIDtlE HStj III
iiauiD: soon unica: sonmsi
1SI1; VIITtD nUCBOi; HITtB STHIS;
IIII; I1IL3; BITICT; IITIBOII;
KSE1IC; E01CI; CIDBTU1; CBI08IOB:
cciiit; coppsi; mo; HiBcnsi:
IICIEL: SEtziiOB; Til; TIUDIOH; IIB
Ectinnoi: mini. POPOL»TIC«S;
HOlCCmOHTIOI; BTOIIDIC1TOIS: LUC
icitotioi; tcroimot sxvosati; BITES
iciinnoi; tnci BIEIIBTS; mils
IBIEBEHCS
Jankiaa, D.».
W79
BS»-600/»-79-0»9. 18»
ft-

















tlOliB*
 it
 IVI •>«.*««, B» -1.2J C,  BP S9.*T C. TP 1 BB 9g at -60 C, 10 BB tg at -30 C
tissoi
3«7*
Ereatk
-
367S
lair


SltOSOEE BOVTt
iBBBlatlOB




lUimcil
BRBOD
Pill




OF CaSSS
	
1




B1EGI
»0-0.01 Bf/CB B



-
BEaB
lot glT«a




GiiEttL iircmixoj
-
lltar aatosotive Pb kaltde aeroaol
•iposare. Level* a {auction of
{article Bin. Extlaated fro* qraph.
lllal Taliae of eboet 900 ca a aad
reaplratorT EreqaeacT of 15
CTclec/ala aaiatalaad dnrlag 10-Bia
• aipllag tin.
ISIJIH: BBOBME; C1LCIDB; CBUBIfB:
I HI; lITORami; 11ROSPBHE:
tlBIICOUTES
9«fle». 2* leprcseatatln
pre-aBalTala treataants are
tabilated. IBB (•uibllltT of a
holistic, io-*aBli policy for aalr
imljtls li ntliaed and a«pport«d.
iifiEi; Ti»ci Eiinns: HUB:
IISTSIIII: BElSnSBeBT IETBOOS;
CtTILS: EBOTEIBS; CORPMATITE
ivuntiois; itonioi!: IBTIBOBI;
IISIBIC; BUIOfl; BBOBIBE; ClOHIIg;
ciicuji: CBICEIII: cnoHioi; coaiti:
CCPPEI: SIUIQII; GBSHlItDB; SOI.B;
ic ens: iso»: niTHimn; L;IC;
tetiB9nv«; BICIIL; PBOSPBOBOS;
ICTISSIOT; SUBIBinH; 3ELEBIOB;
JIIIC01: SHIgg; SOBKId: SlaCHTIOS;
sitfBB: TIB: TnaniR; TVISSTEB;
tiBt: mceiim
KnUfCE
p«Baedeie«r< 6.e.
VlBchester. J. V.
EBtrlroBBeBtal scleace
aad Tecbaology
9(101:971-972

Calttleboroegh, C.
1990
Science of the Total
EaTlroBBeat 1*: 53-75


                                                                                                                                                                                             (Ji
                                                                                                                                                                                             Ul
                                                                                       (BEIT

-------
      Eroalne
      7726-95-S
      II
      lt» 79.904,  S3 -7.25 C,  BP 59.47 C, TP 1 » 9g at -60 C.  10  M Eg at -30 C
IXSSII

3676
Hair










ZIPOSOB1 ROOTI













tULTTIClt
RETBGD

11











1 a us BEE
{ OF C1SZ5

«) «
b) «0







|
I
1
| B1IGE
1
1
1
a) 0.7-93. 1 ag/o
b) 0.3-273.2 ag/g










BB»I

a) 1.6 «g/g
b) 5.0 ng/g
•eiians









GIIEEJL HFOBB1TI01

i) Coat DO Is
B) Saltlple sclerosis patints
Sllples ten 7 scalp sites in each
tatjfct.

C1K1D1; IIIOITS; CEHIBil HEETOIIS
STSTF.H oisEisES; a»is: ILOBIIOH:
EtOnllt; CIICIUB; CB10BIJTI; CO?PEB:
ccic: loom: imsiWBSE; BBTILS:
SfLErlVf: SIITKB; SOOIOS; S\JlPffB:
finiiun: ri ic

ES/BBEBCB

Byao, D.I.
Bolzbecher^ J.
Stuart, I.e.
1978
Clinical cha.lstri
2»(11) : 19*6-2000






    fataM
    1C6-97-8
    C'-BIO
    II :».12, BP -138.35 C.  SP -0.5 C. TP 2 at. at 18.9 C
f IISSUK | KIPOSV1E 80DTE | 1I1LTTIC1L | IOSB5E | B1I5B
1 I | SPTHOD | OF CASES I
II 1 II
II 1 II
1 3677 | I CC/BS |8 I lot detect«d-9.» ug/ir
f Ereatl f 1
1
I
1
1
I
I






1 1
1 1
1 1
1 1
1 1











1 I 1
(
1
1
1
1
1
/












I III! I GEIJilL MFOBHITICJ
1 1

3.9 ag/hc














Ceipent related to notial
letabolis*. lo other detail! giren
Ctrcgenlc saapling technique.

Realthr lilltarr and cirlllan
eiplorees, D.s. tic Force School of
Krospaec Seticiae, ages 23-47 ji. 3
e tot«rs.

eilTHES; CBICBIMtTED HTDBCClBBCIS ;
CB10SII! OIC11IC COKPOOfDS:
CI10BOB!»EIIS: FL3CBISE COKPOIHUS;
JBtlTB; EICCBOLS; TEI1S; 1C01TS

BEIESZBCE

cenkle, J.P.
Ca.p, B.j.
Velch. B.E.
1975
IrchiTes of
FDTironrectal Health
30(21:290-295







      alcohol  (8 ct)
         l  f9 CI)
71-36-3
C«-»io-O
81 7«. 12. SP 117.5 C. TP 5 ••  Bo.  at 20 C
1 IISSM
1
1
1 3678
Breath


zirosoBi soaiz



1 t IUTTJCJI
HETHCO
oc/as


insta
or cisss
a


tues
lot oetected-35.0 ag/hr

(»n
mil
'.1 ««/hr

HUl)
GfHMI IIFOIUTIOI
ccifotad related to aortal
Mtabollsi. lo other details give*
Cryogenic itmllmq t«ctniga«.
Baalthr ailitary and ciTilian
etployaes, D.s. lir Force School of
Ictospace e, aoes 23-*7 yr. 3
linkers.
tilings; CltOIIIHID BTD8CC1SBCSS;
cncim OBSHIC CORPOVIBS;
cncBOBiiznts; r»ctt» COIPOBIBS:
fiiiti; iicctoLS; tuts; icntts

EBFEBEBCE
Coakle, J.P.
Caap* B.J.
Reich, B.t.
1975
Icchives of
CnrlroaaeDtai Health
30 (2>: 2*0-295



-------
Iitrl alcokel (8 CD
1-8«taaol (9 CI)
71-36-3
ca-no-o
II 71.12,  BP 117.5  C.  TP  5  » I« at  20 C
                                                                                     (COETII3ED)
TISSUE
3C79
Breatk












EiMsrai tovn














iBiiTticit
8ETBOD
SC-HS













•mast
or cisss
5* (387
saaples)












S1ME
lot gira














1.» ng/1
Geoaetric












GZBZMI ifrosaiTioE
Beamed at 25 C aad 7(0 aa Bg
36.2* occurrence
lover aad upper one-sigaa Halts 0. *1
and «. 8 nq/1

flea-lthy, 18-35 yr old, nonsaoking.
at tan blacks aad caacasiaas.
Chicago, 11. Bigldly controlled
experiaental conditions.
EBIHB; 1 ICC SOLS; I1LIMIS; 1DU11S!
CB10BII1TZ1 BIDBOC1BB01S: lOllTILB
CIGIITC coipcmis: RZILTB B»?IBDS:
1IB1111ICI; BE11E01ISB; BITIEOLITIS;
ICJH11TIOI 1IPOS8BE; UBB1I 1BE1S
lErEBESCf
Krotosz]nski, B.I.
Braaean, G.8.
O'leill, H.J.
1979
Jonraal of Jnalytical
Toxicology 3:225-23*








Cidaiaa
 ca
 Itl  112. M. 8? 321 C, BP 765 C, TP  1 aa Bq at 39» C. 10 •• Bg at «86
1ISSV!

3680
lerta
















3681
Blood







EIPOSOBE BOOTE



















Inhalation








iiiimcu.
nTTBOD
•1

















115








IDHBSB
or cisss
3


























I1IGE

Bone detected

















0.7-3.8 ng/1








BEII

lone detected

















1.5 og/1








6EIIB1I. IBrOSBlTIOl

Bales

Pcoa a groap oC 61 autopsies.
fetensic aedical •xaaiaations, Japan.
Bales, aeaa age «0. « yr. resales.
•eaa age 37.4 yr.

TBICE ILEBEITS; IBTOfSIBS: J1P1B;
•mains; IBSCTIC: CISBTOR; COBILT;
CBBOnnB: CCfPIB; IBOI; HIICOEI:
iigiDB: BieiisivR; BIBCMZSB;
HtlDHJl; 1IIIBOII; SClIOinB;
StlEIIIB; TI11IID!!: T1B1DIOB; ZIK;
ECLO: BBOBIIt; LIVES; KIDIETS:
CIBIBBDB; CIBEBE1LOB; HS»BT; BDSCLES;
EIICBEIS; SE1BEI; LOIGS; 1OBT1;
ICT1LS: COBP1B1TITE ET1L01TIOVS; SIX;
rCBHSIC HECICIIZ
12 saaples
Direct detettiaatioa and extraction
ctocednes agree.

Iclders, garage personnel aad patty
•crkers in Svedish airplane factory.
.
I1DOST«I11 PCLLnTIOI; COBPlBlTIfE
iTiioinois; ciDBiDB; SVEDZI; icms;
EIOCD; US HI; BI01CC050L1TIOB
BZrEBERCE

Tnkava, a.
Svzaki-Tasnaoto, B.
laano, K.
Terai, B.
1950
IrchiTes of
ZnTironaental Bealta
35(1) : 3(-*a










Lagesson, T.
Indrasko, I.
1979
Clinical cheaistry
25(11) : 1948-1953




                                                                                      («EII P1GE)

-------
Cadalta
Cd
»t» 112. ««. It 331 c. SP 7SS C, TP t •* »J 
1 I aaaa for a»d anflraaaantal afraeta of 1 Tolpa. s.
1 1 Cd, as rapactad tr tM lataraatlaaal 1 1979
< I laat tine Orqaoiratlon. I Cadalaa Basaarct Diqas
1 1 1 lo. 1, 24 J>P.
I j I smn: CUB ma: anus; iMsoBmn i
f 1 1 SttJOBSj II fITO llHTSISi BtOOD; (
r 1 I OBIII! EIDItl BISHSJS; SOIB 1
I i I cisusts; cccorartoiii Distisxs; i
i i I fcmiixoi inosiTBE: IIOITSTIUI. t
1 1 I fCUOItOI |
1 1 1 1
III t 1
J«» I Iijaatlot | a) M 1 a) lot atiata a? 0. IS >g/IOO al 1 al JOT* Itrlag < t It* from aaaltar | Bucks* , 3.r.
Mood | laialatloa b} 20 1 b) lot gli«a b| 0. IS aj/'OO §1 I b| elcl* liilas < 1 ka team aaelte? 1 Boala, a.
t
|
1
1
1
f
f
1
1
1
1
1
I




3695
alaod










3««C
Hoot





^




c) »0 t c) lot gl*aa c) 4.11 og/100 tl I c) Cklldraa at 2.5 ka froa aaaltar 1 laiaar^a, 1.
d) 19 | d| »ot jiraa 4) 4.1 ag/100 al I d| sroaa bof* | traaax, p.
at 1 | al art ftr«a a) O.W ag/100 al 1 a| Irbaa airla t cla«Ts-Thgc«»o, r.


1
1
1
1
















* »


































\

i) «J If) lot fl*a«













a) 70
b) «0































a) 0.02-t. »5 »9/10J al
ft) 0.05-9.SS ag/100 al










.3-29.0 «g/l







\
f> 0.08 at/100 al | n laral ekildraa | lafoatalaa, L.
aaitlaaB 1 latiaatai fcoa qrapk | Terdafa, 6.
f | 1980
f seiool-age ekildrao Urlng tear Pb I CBTfcoaaeatal Ba«ir-6
I caaltar in 8«lgi». Controls froa I 22:95-108
1 oral aaO trtau araaa. |
1 «
t uieatiss: c»m«: ustnc; issraic i
| Ciffinc CO»PCB>BS.- CBUBBIl; |
J IBttSIlUt IIBOSPHHIS; StttllXS; |
I IITltS; ILDCC: OEHJ; BZLGNB: 1
I »c;niTioi inosBti; mil iai»s: f
I oBfii tins i
i i
I i
at 4.12 « or - C.01 | a} ceatroli | lawarrs. s.
ag/100 al | t| tasljaet* of foil (tad arag I Joels, a.
BJ 0.1« * or - O.«1 | | taraard. i.
•7/109 al | Icaaa, aaaa ag« 82.3 rr, fr»a I laekat, J.P.
(S.I. 1 | C4-«ollata4 ataa Kiaqe) , aad 1 1989
1 central*, aaaa aaa «1.1 rt. froa t Iota national IrcalTea
I Ctaclarol. lalglaa. I of Oocapatloaal aad
1 t tMicoaaaatal Raaltk
I 1100B; BIOOO niSU: UHIIS: ClBariS; I 15:2T1-2T*
r tilt: XNCD31] 1IK; ICIilS; SBtGIOB; (
t isi; porvtuioi nrosvu; mismu i
I fcLtirios; stntns: MDIEI nsiisss i
i i
lot 9l*a» | cccaaatloaallT alpotad (-39 IT- lo 1 lblgi«o. I.
I ctkat 4at«ll( ql»a. | «attaa«a, S.
t 1 W»t
1 33-»» TC olta. Sta&aa 1 fhialca la BadiciM a»l
1 1 Jlolaji J6(1):1?-2S
\ »tnt«: Bioct: xinnsi ntint n t
l IIIQ i*»VTJtsi tBismiatn >nao»s; I
I cxiramt occOTVtiotn wtmj: sniis \
	 I 	 \ 	
































Ul
CO







































-------
Cadaiaa
7«ao-*l-e
et
lt« 1t2. «0, BP 321 C. B? 76S C. V? 1 H Bfl at 39* C, 10 u Rg It »8S
                                                                                      (COBTXBIED)
IXSSBt

3C87
Blood.
plasia













3688
Blood.
sens



















3689
Blood.
aan*



















BHOSVSE Bone

Inkalatloa
























































ABAlRICAl
BBTBOD
US



































US




















	 iBBBSB 	
or CASES
•) 60
b» »5
e) 70



































a) 260
b| 260




















EAESS

a) O.OS-O.S5 ag/100 al
b) 0.01-0.28 ng/100 Bl
c) 0.02-0. IS ag/100 el



































a) lot 9i»e»
b) Bet «i»«n



















(BER
ISAB

a) 0.13 B9/100 Bl
b} O.Oa B9/100 Bl
e) 0.10 ag/100 Bl
Geonetrlc


































a) 16.* « or - 6.3
ag/1
b) 1.2 * or - 1.1
a 4/1-

















PAGE)
CIlMAt IEFORHATIOI

at Iesid««t» of Liege (aoit collated
area)
t) Besideats of Brussels (less
foliated aceal
ct tesileata of Charlerol (eentrol
atea)
lleea residents differed fros
Charlerol (p<0.01) aad froi Braisels

-------
CatllU
Cd
ttl 111.10, BP  321 C.  BP 7«5 C, TP  1 a* Hg at  39* C. 10 n 19 at «86
                                                                                        fcomiota)


f
IISSII
BOW
3691
Brail
xtroscm IOBTB


Bair
1
1
693
ale

aiiimcti
us
it
- -
it
i
i
'vasts
or ctsi
i

1 US a| 31
b] 22
1
1
1
f
1
t

tuet
t3 tot ippiictblt
b) tot applicable
c) lot applicable
1) lot applicable
a) (one detected
b} low detected
c) lone detected
d) lone detected
•iii i Gimti nnnmo* ismsacs
l
i
if 8.3 fs* l tt Spiae, aeanred tr US Slaiier. J-»-
b} 2fi * or - 13 ppe I tl Spiae* aeasured *y It ldiaar B.C.
c) 3.2 ppa | c| lib, aeatored by US Bce«er, 9.9.
11 2.1 ppa | 4] renr. leanred IT US Barrey, T.C.
1 1*80
I Ktopaf ip*eia»a». Bittetrj plate Illtiai Joina.1 of
1 aaker, aorted iltk Cd foe 3« 1C. Icdsttrial Seilcioe
1 37.-278-2M
I fOIR; KIC1ZTS; IITIB: IBTCISIJS;
l ciDni*; aniLs; occratiiottt
I BmtDS; OIIIJD niGDOR; OCCOPHIOIll
l [isiisis; aim i
1 1
a| noae detected I a] Riles, cerebtaa, t nblectE I Tifcaia, B.
b( loae detected | t) Feialas, cerebn*. • nbjects t SnaU-Tansota. B.
c| gone detected I cl Bales, eecebellw, ( nkjects I taaao, K.
d) loae detected I 41 leeales, cerebellns, 4 lafcjecta 1 Tetai, 1.
1 | 1380
I tioi a gtoaf of Cl aatopcles. I Icehires of
1 (oceulc eedicel exasiaatlOM, Japaa. | laflrowental Vealtb
I Bal«, eeu a«e tO.S rt. leaales, I 35(1) : 36-«(
1 ieaa aae 37.1 rr. I
1 1
1 tsict ttEtitrs: iiropsrss: JIFH.- i
i juranui1; nstxtct ctasnas cososi i
i CVlCBIQf; CC£PEB; IBOlI 91KCCBI; F
1 iriru; nieitsite; nisiaist: i
j meiom; iiiifloiT; scamof: 4
I SfLIBItl; TtlltHTK; MltDIta; ZIK; I
1 «CIt: BOTBIf!: IiriB; BIDUIS; |
1 cntnm; ciBSEiittia; BUST; BOSCIES; i
l Tjirnis; srrinr; IIBSE; taiti i
I BITIL3; COaPlBtlirg irilOlTlOIS; SIX; I
I tctiisic gieicm i
1
lot qirti a) 1.72 pp« a) tea.nli« JisafcUd | P16I, F.O.
lot gireg b) 1.08 ppa t) Controls t Parlies, '1.
I 1»T7
l«ani>4 disabled tad norsal 3rd and I Selene*
atb grade stideats i* Caaada. I 19S(«3I3) t2M-2O«
I CIICI01; RteilSIII; POI1SSID*; |
l i scriM; ciEHina; costif; cotnsi: i
I ItOl: HID; MIGaltSt; ZI1C; I
I ctROKina: ixtflMit amcnst: anus; t
t 1(11; CSIXJBfl: Clltlt |
1 1

1 t
J leTiev* 21 repcesentatiTe | CBittleboroff^h^ <*•
1 pce-aaal?sis tr«ata»nta are | 19S9
1 tatalated. Tie Ceaslbilltf tl a j science of the Total
1 kcllstie, BO-nsb pollcr fot kaic I Emlconaeit »:53>75
1 laalysls i» ovtliied and supported. 1
t tiiin; TBtct titmns; snt: I
1 IUSTSH.H; BftSffiraiBT BITEOCS; |
l itiusi tRcitits; ccatuitin t
l mumais: UOBUCB; tinscn: i
I llSItK; BlllOa; BBOBtM; C1CJIOB; f
I ciicns; ciLCiiiz: caiosina; conn; i
l ccppti: siiuoi); BitBuinB; coit: i
1 ICDIll: MCI; LimiJUB; lilt: |
i iiensnn; Biiemsi; BSBCDM; i
I ECITBDI11H; IICK1I.; PSOSPHCBnS; t
l tcussiii; minim ; SILIIIOB: i
I E11ICOI; SILTES: SOIIUB; SIlCITlnB; 1
1 SVITm: Til; TITtlllfl; T01GSTII; I
I 1I1C; IHCOHD1 |
1 1
(IE1T FUSE)

-------
Cadlloa
7«fl-«3-*
Cd
»ti 112. M. BP 321 C. BP 76S  C,  VP 1 si Eg at 39* C. 10  »  19 at *8t
                                                                                        (COITIItlED)
ixsstz

369*
Hair






,„,
Bale













3««
Balr



















3*97
Beart














EEPOSVR BOJTB





























































1IILTTICU | IDBBSB
•EMOB
»CT







n



































ii















OF USES
1







a) »
b) 7
0 11
4) TO
e) 10































a) 10
i) »














UMZ

0.66-3. ea 19/9







a) lot given
b) lot glten
c) lot gl!








CIEIT P»GZ(

-------
CaJalta

7«ao-«-9


Itl 112.10. IF 321 C. SP 765 C,  TF 1 »a Bo at 39» c,  10 aa  Ra. at MC
                                                                                 (COItKOEB)


TISS3I
3698
XUa*T
3699
THaar (
I
1
t
3 no
ii4a*r
mason ton


i
i
aBumcu
BATBtJA
US
M
US
1
1
nriMti i met
OF C1SSS |
1
1 a) lot tint
1 ii lot «irw
1 c) Bot giro
1 A) lot glm
1 •) 5S1-1B9I pp.
1 t) 833-939 pp.
I g| 200D-4000 ppa
I t) 1230-2850 ppa
I lit «t
1
1
1
1
1
1
t
i
t
I
- - 1
•) 19 1*1 5.6-110 ag/9 (wt «(
b) 3 | b] 5«-«T aa/g (Mt at)
1
1
1
J
1
1
1
1
1
1
1
4
1 1
1 1
1 1
1 I
$ J a> 1.67-13.1 ag/»
J | b] 2.3V-37.2 «J/T
12 | CJ 0.503-27.6 aj/j
1 let rt
1
1
I
1
t
1
1
1
1
1
1
1
I
r
t
i
BUI i eiieiu monunoB i nnmcs
i i
i i
t i
a) 3231 ppi ( (I 17 caaear patiaats | Baaacc, O.I.
b) 20«1 pp> | t| 58 BOS-C«DC«C p»ti«at« | caloccl, l.Y.
c| 1188 ppi | c| 1ft Kttaiotecs (a«nr a«at«a) I lasaalUjia, T.
it »« ppa | a) 5 laokara, 1.5 packs/oar 1 Illllaaa. Jt.I.
•) 1221 ppi | *) 2 »al»s, «9«a 10-11 71 1 Ftakaclon. C.
t) »fl1 ppi | f| j «» 2197 pp« 1 M • (aaal«a. a««a 50-59 re 1 S.JiclB* 1S(12) :95«-9«3
ask »t | |
I Ktcpatva ftaa hospitals la forth ud I
1 feath Carolina. Marts and I
1 caecaatui. Halt*, *q*M 16-91 »r. I
1 Calldiaa, «i«a I al*a I Tnka*a, B.
(«*t it) ) t) Taaalaa I SaziU-Taavaota, B.
>| «0 + or - 6.7 ag/q 1 1 taano, K.
;«st «t) | ma a 7roof of 61 avtopalas, I T«ra.i, E.
( tcxa»ic mtitctl enainatioas, Japan. I 1980
1 >al*a, aaan aaa 40. 6 rr. f«aalaa< I Jrctl»e» of
1 aaaa aq« 37.1 TT. I EaTiroaMatal B«alth
1 1 35(t|:3C-«*
I nice KS8ZIH: tmotsisss JJP»I; t
1 iKmim: tissue: cjnaiirs; COBW.I: i
l cnomas: const; icot; BEBCMT; i
1 iititrB: BiGitsios: iineuisi: i
1 IBSICIOH: IITIBCIT; SC»»DI05; 1
1 sitnimt tiiiiios; TjHBiijjt UK: i
l eciB: Bfanic ixrn: KISMTS; i
i cisiMia: CIIEBIUOI: n»»; HOSCIBS; i
l incBiis; svixn; niesi tcni: i
( tttltSs COSFIMTln UTU.D1TIOKS; SIX; I
r roiifsic RICKIK i
i t
i r
a) 2.< o oroof II. 1
t Ceatrol*, aon «3-72 yr. «ao llwd SO 1
1 la fraa tb* factorr- Sawdai. I
1 1
l siiDEf: CIHTISS; tnttrsi LITEI; i
1 It IBS; CODUmlTK IIStOlTIOIS; I
i iicvsniii Bieizis: nisaiiBin i
1 KTBOB5: JITIBOrr; IBS MIC: CWIXVB; I
l cismi: c BIO ting; CCMIT: coteii; t
1 eets; I8O«; IIITUIDB: L»D: (
I iJieiBisi; BISCUIT: BDITBEIIDR: i
| EMSFROtOS; SBBIDID1: SCllIIOB; |
1 MI Hi-ii; sum; TI>: raiesnf: i
l me: win niuas; notismti i
1 fiirrs; sBtneis; TEWIIIHB i
i . : i
(ini notj
                                                                                                                                                                                 o>
                                                                                                                                                                                 ro

-------
Cadslui
7UO-B3-9
ca
111 112.40.
            IP 321 C, B? 765 C. TP 1 aa Bg at 3M C. 10 •• Hg at «86
                                                                                      fCOITIinBD)
TISSUE

3701
lidaer










3702
XidBay













3703
Kidney









370*
Kidney







IXMSOn BOBTI




























Inoestion



















1IUTTICU
aZTIOD
US
11










I*


































IUHBEB
or cisss
1











a| 19
b) 7
cl 11
d) 10
•1 10






























BUGS

a) let applicable
b) lot applicable










a) lot given
b) lot given
c) lot given
d) lot given
•) (Ot given






























III)

a) 77 ppa
b) SO » or - 20 ppt










a) 0.07 * or - 0.06
ft*
b) 13.33 » or - 22.72
PP>
o) 8.57 * or - 3.97
ppa
d) 2*. 10 » or - ia.10
ppa
e) 20.89 « or - 12.26
ppm
let *t
























GEimi iirosBitioi

a) Measured IT IIS
t) Beasured by It

latopsy speciaeBS. Batter? plate
•alter, vorted «ith C4 for 3« Tt.

Cateoaalacia. reaal tabular
disfaictioi
tens; KIDII1S; LIT IB: ITCCESXIS;
citBMB; BitiLS; occo?iTto»li
BIHBDS: uinsD nisDOH; ocajpinosiL
ciszisis; mm
a) Ibortases
b) »9«a 2-5 ir
c) Iges 13-11 rr
d) Iges 25-3* TC
<) loe* 65* jr
late also aivea br race a«d
occupation.

Igtopaiea of accitental deatlis in
Ckio, ages. <1 ao-qteatec thao 65 ji.
aid abortuses.
mils: OOBIDI: HUE; KIDIIIS;
iitn; ttttofsns; smnis: icstccos;
1«I; FOPOUTIOI BIPOSBBB: 1BDITS;
itotEscsns; CHiiDBii; runs; OHIO
t«
-------
Ct
»t» 112.10. tt 321 C.  >P 7*S C. T* 1 » B? at 39» C, 10 n H? tt 186

IISSVX | JIPOS1JBB ROOM <»JITTIC»I inaljn | )»GX
I BBTBOO or CJSSS |
3795
KUMT
3106
Xidoer
3T07
Kldn.T
3708
ii fear
f
Inialatlot
1
1


1
1

m
May
Sp*ctroMtcT

»
it i3
b) 10
s

»0t «iT«»
0*9*57 ig
c.»-ii.8 ag
1*3 4C* ttolcal tt acute |
I (caiaoDitif. 1
1 1
I BHIH nieici: IIDHTS: ijfis: i
I lines; trtiH: stii-j BJUBDJ; IRU. i
I rciscwirs; HDVSIIIII itaostmis: i
f HRiiiTiei: cocnp»Tiofu nzuas; i
I cicaMi; SIT t is: inropsirs i
l i
a) I5.J * or - 2.) a? a) forkari, cd ptocaosinq plant < fllla, I.J.
i) 3.7 * or - 2.9 19 t) Cottrola | Bocqu. l.D.
Woaatcie | zanzt, I.
Baag* at critical l»r*la for I Tasaaara^ S.
Ca-l*docc4 titular »cat«iaarta 1 Tarts*;, 9.
•atlaatad at 150-304 tg/1. | Cot*, 5.B.
1 1*81
ItntTS; IIDin DISMS3S; noOTS; 1 Jooraal of Toilcoio^r
tlfSB; IT 1TTO 1IU.TSIS; cigilDB; I ««J InrircBaBntil
(KUST OCCOPJtTIOIU H1318DS 1 Malth 7:491-703
1
lot glT« Talves foe cort«i. Occupitiooallr I Jltlgrai, 1.
eiTOMi S-30 ic. (a atkcc details 1 Battssoa, S.
9i»ai. | 1981
I Pifalcs li S«4iciM tal
33-M TT oUj, Sndn | Biolofly 26(1):1«-2«
1
j coirs ; BICCC; ITIDIITS: mm: Tt i
fltO UaLTSIS: BMSOEERIt BIT HOBS; I
CIEtlOR; OCCOfHXOBU. BlUBDSi BTTiLS I
1
(«trt MGE)

-------
CadliBI
7»4»-43-9
ca
lt« 112.40. IP 321 C.  BP 765 C. TP 1 •• Bg it 394 C, 10 n Bg it *86
                                                                                      (COITIIDBD)
1ISSDI

3709
ll»«














3710
liMT
















3711
liver




















3712
Liter








EUOSDU MOTE

















^___^_^^__

















































1IUTTIC1L
•ETBOB
US















11

















US





















us
It








ITHBES
Of CUES
















a) 8
b) 6
















a) 8
b| 9
c) 11



















1









MICE

a) lot givea
b) lot given
c) 52-281 pp«
4) 75-605 ppi
laa vt











0.66-11 ag/g (vet «t)
b) 2.4-1S ag/g (vet vt)
















a) 0.071-1.16 eg/g;
b) 0.080-3.21 ag/g
e) 0.0010-4.8 ug/g
Vet vt


















a) lot applicable
b) lot applicable








•111

a) 2«8 ppa
b) 2*4 ppi
c\ 143 ppi
d) 287 ppi
ish vt











a) 4.2 » or - 3.5
»g/g («et vt)
b» 8.9 * or - «.5
aq/g (vet vt)














a) 0.32 og/g
b) 0.96 ag/g
c) 0.72 ag/j
Vet vt
Bedims

















a) 172 ppa
b) 210 * or - t ppa








GEIEI11 mOIUTIOl

i) 17 eaacer patleats
t) 58 BOB-ciBcer patieat*
c) 10 BOB— Backers (never snoked)
a) 11 siokars
c) aid d) 40-70 yr old aal«s.

•atopsies fro hospitals la lorta and
Soith Careltia. Blacks aid
Caacaaiaas. Adults, ages 16-91 yr.
CitUraa, tgas 1 days-t jr.
i IT its; softs: inEi; HOISTS:
« CHITS; C1IIOBB1; CIDBI0B; II»C:
HID; 10 wi cuouii: SOOT a CMOLIII;
inopsm: HOICCTIOI.ITIOI: IICIIL
siniiES; net: swntxsi TOBICCOSJ SEX;
IIOPII3BS
I) 1«1«S
t) Teaales

Iioa a groap of (1 aatopsiea.
forensic aedical exaaiaatlons. Japan.
Bales, lean aga 40.6 yr. Teiales,
a«an a^e 37.4 yr.

111CC tlEBIBTS: IBTOPSIES; JlPlI;
unBiHB: iisnic: CUBIOB; COBUT;
cisoiiina: ctiPiB; i»n: Biicrat;
IIOIOS; S1GIISIOB; ailCllESE:
SIIEIII*: timiodl TIUDIIB; tnc;
CCIDt BBOBIII: LirEB; UDBIIS:
ClBEBtIB; CtEFBIIlUB: BHBl; BOSCIES;
IIICIE1S; SPIIB1; LOassj 10111;
B1T»S; COBFIBlTin ET1ID1TIOIS; SE1;
ICBIISIC ISOICIIZ
a) controls
B) locker grogp I
c) florker grcap II

Caceascd reflaecy and snelter
•orkers* aqes 55-76 yr, exposed to
btiTf ntals 1-3 decades. Tlae
tetveen retireaeot and death 0-1.5 yr
ill IJIDIS I and 2-19 yc, groip 11.
ccntrola. aqes 43-72 yr, vho lived 50
ki froa tbe factory. Svedes.
Slttll; Cltims; ItHlITS; liyiB;
IOISS; COBP1S1TITI E11L01TTOIS:
IECOST8I1I BISIEK: RISOBEBIIT
B1TBODS; lITIBOXy,; 1BSBIIC; ClDBIOa;
CISIOB; CBBOBIUn; COBlLTi COIPEI;
GCIDi IHO»: llTTBllOa; LEAD;
BIBG1MIS1: ntBCTJBI; BO1TBDEI03;
IEOSPTO80S: BOBIDinfl; SCIIDIOB:
51IE*ID1; SIIVES; TIB; TOIG5TEI;
IIIC: BIllTt B1ZIBOS; IVDOSTBIIL
FIltTS; sniIEBS; TIIIOBIOB
a) ae&sared cy IAS
t) ••asnred IT la

Intopsy speclieos. Battery plate
Baker, vorked vith ca for 36 yr.

BOIES; KIBItIS; J.ITIB: IUTOPSTES;
C1C8IOH; H1IIS: OCC5PITIOIH1
EIHBDS; 3-IHtD KIIGDOB; OCCOPtTIOVU
tlSItStS; OB HE
EZRtSICI

Baaier. D.I.
Calocci. 1.7.
BasselblaA. T.
(illlaas, I.E.
Piakerson^ c.
1973
Joarnal of Occapational
Hedicine 15(12) : 954-563








Takava, B.
Sazakl-yasaaoto. I.
laano. (.
Terai, B.
1980
IrchiTes of
iBvironaeatal Health
35(11:36-44










Brone« D.
fordberg. 6.
tester, P.O.
1980
science of the Total
Environment 16:13-35
















Blainey, J. D.
IdUS, 5.0.
Braver. O.S.
Harvey, T.c.
1930
British Joan a 1 at
Industrial Beflicine
37:278-284


(HIT P»5S)

-------
      Cidaioa
      7MO-»3-9
      Cd
      It* 112.10, » 321 C, Bf 7«S C, W 1 » Be at 39* C, 10 » Hj  at «8«
                                                                                            (CORIITOD)
IXSSBI i nvosm nati i amnxcii i
i i stmat i
i i i
i i t
3713 |
liver 1
1
1
1
1
U 1
1
t
1
1
1

1 1
1 1
f 1
1 1
1 1






IIUZBI |
OF CASXS |
1-
1
•1 19 I a)
c| 11
d) 10
«> 10





1 >)
c)
V
e)





1
1
HMS |
1
1
1
lot girts | a) 0.01
lot alirea | ft) 0.33
tot gl»e» ppa
lot alien
lot alien







O 0.97
ppa
d| 1.25
ppa
e) 1.97
PP*
let »t


9B1I

ppa
« or - 0.35
* or - 0.«9

» or - 0,75

* or - 1.08




l ' crntai irroiiunoa
l
i
i
1 a) Jbottnes
I 61 soe> 2-5 rr
I c) aoea 13-K fr
| d) iges 25-31 rr
1 e> Joes «5* jr
1 Cata also qtrea tr "c« «J
I ccctpation.
1
1 iBtopaiea of accidental deaths la
I Cbio, a«aa, ber 7, 1975






 I
 I
 I
 I
 I
 I
 I
 I
 l
 I
I
1 1 1
1 1 1
1 1 t
1 1
1 1
1 1
37T« Imq*atiom | I
Unr t 1
1 1 1
1
1
1
!
i i
i
i
i
i
i
t
i
i
i
i
aed abort****.
tints; ctDinii mil: EIBHTS;
XXTIB; IBTOPSISS: s»o*iw; ICBJCCOSJ
jes: fo?njinw rwosraij mans;
ttoiiscnrst antnttn rms? ono
enl«r. Profil* of taaltbr «nb]»ct«.
(as«ll»* dati for d«t«r»i»ins ekaiigM
IB ntrltiaMl atatas Iroa ItdostrUl
1
t
1
1
t
(
1
1 Sttart*, B. J.
f Rott«son, s.r.
1 1»7«
37T« lagesuos III 1 Cerle*. Profile of kaaltar nb]»c
tirer III 1 (asallaa data for deteralalae ekaa
1 III I ia n«triti«a*l statas fro a Itdoatr
III 1 feed prooessioa tecnniaies.
1 ' 1
II l tit Hunt; 1D01TS; riTVS; 1IT1IT
l l l BIOCII siBim: ui«; KID»TS: inn;
1 1 1 em; imn: mits; FOODS: SOILS;
III l TiejT»Tlo»: ciBsira: coirxts
1(1 I lUSHXSt: B1T11S; TMCI SUBSflSi
III 1 tlK
1 1 1 ,
« » 1 1
3715 1 Inkalatloa 1 1 lot jlren «.« ao/9 »•« «t I 34 sin eipoeere
liter 1 1 1 litopsr tisaae
1 1 1
II 1 I 3« r* old selder
111 II
III 1 Visnaea, persisteat non-prodoctire
III 1 tcogb.
Ill 1
1 f 1 i«atk 5 d«7» after exposare. laxj
III 1 flowed ckaDocs typical of acvte
1 III pteaaoaiti<.
1 III
1
1
1
1 1
1 1
l i
1 1 f
716 I 111 1 a) 83
i*er 1 1 M 10









i DIITII Kiiecci: Kioms: IITIB;






a) 0.8-120 ppa a) 22.* * or - 3.3
fc) 0.6-7.9 fpa ppa
b) 2.6 * or - 2.2 ppa
Seoaetric





t
1
INGS; a tilt; HE4LT8 giZlSIS; ami
rciSOITIG; HOOSTBUI MVOSFHSISS;
IH111TICI; CCCVFITIOfU B1JJSB5;
cicanu; urtJU: »oio?siis


a) lorkers, Cd proeessiaa plait
t) Control*

*aa«e of critical levels far
<4-iaa*ce4 titmlar protelaaria
eatlaated at 150-300 »o/1-

ICBITS: (ItllT DJSEISBS: KIIIITS:
IITEt: II TITO IfUISIS; CIDBlnS;
ifTils: occopiiioiii iiziios

t«. i eatarie, B.I.
ges 1 Kofelason, s.r.
ial I 1»7«
1 »e« Kalaad aedical
1 Joonal (7(<03l:3-B
s: i
l
l

l
1
i

1 tacas, P.I.
1 Jarivalla, J.G.
1 Jones, J.B.
1 S009B, J.
1 Tale, P.t.
1 1930
1 laacet 2(8187) :205
I
1

1
1
1
1
I
1
1
1
1
1 Fills, K.J.
1 Borqso. (.0.
1 Zaaxl, I.
! Tasaaara, S.
I fartskr, B.
1 Coba, S.B.
1 1981
1 Journal of Tozicologr
1 aid ItTlronaestal
1 Bealti 7:491-703
1
                                                                                     (•ire PISE)

-------
Cldsill
7MO-43-9
cd
Itt 112. tO, IF 321 C, BP 765 C. T?  1 la  Bg tt  39« C.  10 II «g at >86
                                                                                      (COmilXD)
IISSSB


3717
Lang

















3718
Ling




















3719
Ing













3720
Bilk








BIMSOBB BOOTB











































Inhalation














IngestioB









1BUTHCU
BEIBOD

Bl


















US














































BOBBBB
or cisBS

a) 3
b) 2

















a) 8
b) 9
O 11



















1
























SHOE


a) lot givei
b) Bone detected

















a) 0.001-0.17 ag/g
b) 0.058-0.78 ag/g
c) 0.046-1.4 »g/g
•at lit


















Bot given
























BB1B


a) 0.90 « or - 0.85
«g/g (vet »t)
b) Bone detected
















a) 0.026 ng/g
b) 0.42 ag/g
c) 0.11 og/g
vet vt
gedians

















4.7 ag/g net vt
























GEBIBAL IIFOBBATIOI


a) Baits
11 resales

Iroi a groip of C1 aatopsies.
forensic nedical ezaalaatiois, Japan.
Bales, sean age 40.6 yr. resales.
staa aoe 37.4 yr.

IlaCB E1BBSI1S; aOTOPSIBS; JAPAI;
llEBIItia; ASSEBIC; C1DBIBB; COBALT;
ctBCBTOs: CCIPEJ: IBOI: BEBCOTI:
IIEITJ1; BAGI1SIBB; BAIGAIESE:
BVEIDTVB; AITIBOBT: SCaBDZOH;
SHSIII4; TI11BIBH: TAIADIOB; ZIBC;
COLE; BSOBIII: UTEB: HBBETS;
CEBEBSIBj; CEIEBELLOB; BB1IT; BOSC1BS;
SIBCBE1S; SHBEI; LOBGS; »CM»;
aillLS; COaPllaTITB IT1LH1TIOIS ; SET;
ICBEBSIC HIDICIIE
at Control*
t) worker groap I
c) lorker grcap II

leceascd raflasry and sneltery
•orkers, ages 55-76 yr, ezpoaed to
heavy aetals 1-3 decades. Tise
b*tveea retlreneat and death 0-1.5 yr
in groap I aid 2-19 yr, group II.
Ccntrols, ages 43-72 yr, *ho lived SO
*• fron tke factory. Svede*.
SIIDBB; CaGaTEIS; EIDBBIS; trTEB;
HUGS; COBPIB1TITE ETalUTIOBS;
tlCOSTBIlL B1SIEBE; aElSOEEBIWT
BIT BODS; IITIBDHT; IES1IIC; UDBIOI:
CISIOB: C1BOBIOB; COBllI; COFPIJ;
GOLD; HOB; IHTBIBOB; IBID;
UBGIBBSI; BIBCnil; BOITSDEIUB:
IBOSPHOBU3; BOBIDIOB; SCJBDIOB;
SILZBlnl; SI1VEB; TIB; TOBGSTEI;
II!C: BEILTB H1ZJBDS; IBDOSTEI1L
ElaBTS; SBEITBHS; TBLL01IOB
30 aia eiposvre
litopsy saipla

3« yr old aelder

Cyspnea, persistent Bos-prodactive
ccagk
Deatk 5 days after exposure. Long
ctoied chaages typical of acute
pteasoaitii.
OIITED KHGDCH: nOBBIS; 1HIE:
IHIGS: nan i: HEIITB UZAXOS; IETIL
tCISOIIBS; IICaSTBIlt UHOSPBEBES;
IIBIUTIOI; CCCOPiTIOBU. BJZIBOS;
ClCBIlfl: BR1IS
levle*. frofile of healthy nbj«ets.
Baseline data for determining changes
fcod processing techniques.

Ill :EILa»; 1DBLIS: EETUS; II'llTS;
ttooi SEIDB: BUB: KIBIETS; urn;
IIIK; B5TIH; DIETS; POODS: SOILS;
1EGFT1TIOI; CABBIOfl; COPPEB;
BalGalBSC: BET1LS; TB1C5 EIEBESIS;
me
IBTBBEBCB


lakan, B.
Sazaki-Tamsoto, 1.
Asano, I.
Teral. B.
1980
Archives of
Eavironneatal Health
3S(1|:36-44











Brnne, D.
Bordberg, G.
tester. P.O.
1980
Science of the Total
EBTironnent 16:13-35
















Laeas, p. A.
Jarivalla. 1.6.
Jones, J.B.
Goagh, J.
Tale. P.T.
1980
Lancet 2(8187) :20S








Gathrie. B. B.
Eobinsoa, a.T.
1978
lev Zealand aedical
Journal 87(603) :3-8






(BEIT PASE)

-------
ctfliiu
ca
»1» 112.10,  BP  321 C. If 7«5 C. TP t mi Bg at 3»« c.  10 u 89 at  «B6
IISSU BXFOSDKI BOOTS 1IU.TTXCU. 1 ITBBSSB JI1BI IBal ( GJI1SU. UTOtBITIOl i RlriSElfCI
HEIECD | Of CASES I I
1 • 1
3T21 U a) C c) tone 4et«et«4
Basel* b> « t) lot glT«
1
1 1 t
1 1 f
1 (
1
1
1
1
1
t
3722 in a) C
P«ncna« 1 J» 2
1
1
1
1 1
1 1
1 1
I 1
1 1 1
III 1
i r i
i i i
3723
srltn
S7J*
otlo«
»

nhalatioa
,
»
n
us
\
\
a) 9
i b) *
t
a) lot «i»«i>
b) Sot giren
) Jot jif«»
1 Cot gives
5-1.2 »g/l
l
1 1
a) lone detected | •) 'fit' I Inlwn. S.
b) 9. 1* » or - 0.27 l t> Feiales I Suafcl-faauoto, •.
ag/q (»t «t| | t IMOO. K.
1 tram a ?roup of *1 xtopsiva, I Tetal, R.
1 | (oceanic cedical muloatlott. Japan, l 19BO
( | Bales, •«•* ao« 40. t re. Feiales, ( Irchirca of
1 i«a> «9« 37.* rr, | tmironaettal E«lth
I | 35|1)t36-«H
t IBICI tiEniis: ioio?siBSi ji»>; i
J 1108I>9«: »5E>IC; CIOBIOB; COBU1; 1
t ceieini; cemi; ttn»; BIECDRT; i
1 noiDg; fnoiisiDB: «a*etiEsi: i
| BOSIDI39; 1HIBOJT: SC1IDII1; I
i fnttii^; TIUH09: Tinnioa; nice; j
l GCIB: itonit; IITEJ: noicrsj i
l CHIBBOS: ciEnmnt; n»i; ivscits; i
l rnciEis: srini: IVKJ: tosti; i
I B«»is; coHrumn mtairicis: sti.- i
i ICSHSIC wmcim i
l i
1 l
a) 1. 2 « or - t.« 1 ») Bales I TuUwa, «.
04/9 (net nt) | t) r«nl«s | Sniaki-UBttMto, i.
b) 2. 6 » or - 3.6 j I liana, X.
"9/7 <«et «t) | Pro* a «couf of «1 autopsies, I Teral, 5.
1 forensic Mdlca.1 araiiutlDU, Japan. 1 1990
I Bales, Mai age 40.6 Tt. Feules. I Irckirea of
1 *
O. 80 • or - 1.6
/j {»et lit)
«V1
a) Rales 1 tataiw. B.
l| F«eal«» | S«aa iq« 37.* yr. | iBTiromatal Bealth
I 35|1):3»-*a
TSICI nilltltS; tOtOPSIiS: JlPif; |
iicama: issMic: CIBSIDB.- cosuT: i
CBBCdlO!; CCEPCf; I Mr: BIBCBET: |
3ICI5J!; usnsiua: MICIIZSZ: t
fUBIBItrS; »»IISO»T: SCHBIOH: |
stLmai: iniiros: Tuinusj sue; f
«C1C; BiOMH; 1JTBE; nniHS; I
CttlBIxt; C»Z9IUna; aXIBI; BOfClSS; I
IIKSltS; SE1KI; LtTIGS: ICB«; C
»»I115: COIPUlTln ITilBHICIS; SEI; I
Kfiisxc srciciK i
1
12 aaiplae | laawson, T,
ClT«et J«t«Tll»atloa «»a •its&ctio* i liAnsto, 1.
icocedvces a^r*e. } 1979
1 Clinleal Ckesistrj
ItlJers, qario* pnraiMl and pgttj l 25(11) : 19*1-1953
letters ta s««di*k airplane factor*. 1
t
iiosniit icixoiioi: coBtuniti i
nnoitiois; ciosiDB; s«!»l»: jtotTs: l
HOCV; i»lil; BtoiccninrLMIoi i
	 , 	 ,. . , « 	
                                                                                                                                                                                  OO

-------
Cadalaa
7MO-43-*
C*
Itr 112.40, IP 321 C, IV 765 C. n 1 ae gg at 3M C. 10 •*  Sg at  486
                                                                                      fCOITIIDEIl)
tissn

3725
Dilne















312*
Urine









31TI
Orlae















312*
Brine








EZpoSBBB BOOM

Iggestloi


























Ingest Ion
Inhalation
























auiRlcii
H FT BOD
US



















































BVBBEB
OP C15IS
•t 34
b) 38
0 22
d| 20
























b» 15
c) 24
41 t«
e| 19
0 7
9) 21
hi 21












1








UBCB

a) lot gives
b) lot given
e) lot given
1} Bot given
























a| lot given
b} lot gl?T4 Tr.
Ccitrola fcot IsnitiH Prefect ice.
Ige* SS->10 ir.
Creetltine clearance and « reaal
(icctlioiaa Eeaisocotloa decreased
algalfleaitly in cd-eiponed subjects.
rrcteinorea, gloco«rea, and
J1PII; aOOITS; K10IIT BISIaSES;
BIOOD; VBIII; EIOiCCOStTLKIOl; iETlt
toisoiiis: tins; IIDJSTSIH
tcmrtioi; CIEBIOH
1 Tevlea of research la Industrial
*aea for aad envlroanental effects of
Cd, as reported by the International
lead Zinc Orgaailatioa.

Hint; CH8IBR; HBT1LS; lEISVtnnt
IIIBODS; II TITO IIIITSIS: BIOOD;
ifin: EIEIIT DISUSES; BOII
HSElSES; OCCOPUIOU1 DI5B1SBS:
FOPtmtioi tiposnB; iinosiiiit
ECIURIOB
a) Coys living < 1 k» froa naelter
t] Sirls llvlnq < 1 ka froa saelter
cl Coys living 2.S km froe enelter
d) Girls living 2.5 ki Iron enelter
e) Drban tovs
f) Vrbai qlrl*
g) Ural boy:
M Imral girls
tatlaatel ftca graph

School-age chilicei living nenr Pb
tnelter in Belgian. Controls froa
rntal anl mean areas.

Biieaitsi: cmsios: usiiic; IESEIIC
CIG1BTC COBPCOIIDS; CHUBtli
IIDOSTIIlt tlBDSPKBlES: SailTESS;
EIIILS; BIOCD; V1IIE: BEtSIJH;
TCPULiTIOW EIPOSOJB: EOH1 tlEaS;
IBEII tins
teunc«4 7 S to it a,f.t«r einos*c«

letopsy specimens. Battery elate
»k
-------
      CalaiM
      T*»9-»3-9
      C«
      HI  112.10, BF 321 C. It 765 C. H» 1 M B» at  39* C,
                                                          10
                                                               Bg «t
        HSSOt
                   EXFOSBBt IOOIE
                                       nunictL
                                        HKTBOB
  |   HBBSS
  I  Of ClStS
  |	
                                                                              ttia
                                                                                                                               eimii iiroKimoi
                                                                                                                                                                    IlfZUlCl
       372»
       Dtlna
    a) 70
    b) 60
   a) o. 002-0. t5S ag/br
   b) 0.015-0,365 «o/kr
                                                                                                                     I
   a) 0.0*0 » or - 0.00*
   aa/az:                 t
   b) O.fl»3 » or - 0.007  |
   tto/kc                 (
   (S.S.)                 I
                         I
                         I
                        I
                        »
     •1 Coatroli
     c) tesideats of pollute! area

     reaea. *»** age »2.3 ji, froa
     Cd-polleted area Ui*?e>, lad
     coatrols, a«at  aoe B1.1 rr, froa
     ttarlerol,  Belgige.

     BIOOO; StOOB FIA5U:  OBIII; CJmlOB;
     nit: iiicntT: tiKs  smis; sstetvxi
     Kit tantuioi KVosnK;  iicnsniii
     PCIHTTIOI) SltllHS;  KIBB1T CISI1SES
     I  l«ol«rjs, B.
     I  »oel«, B.
     I  Bernard, t.
     I  Backet, J.f.
     I  1980
     t  lateraational IcckiTe
     I of occupational and
     I iDTltooMBtal Vealtk
     I  «SlZ71-27*
     I
    I
    I
      3730
      Urioo
                  lakalatloi
                                                                  lot applicable
                                        ( 2000 naoVl
                                        I
                                                   I  30 aia aiEoxan
                                                   I  lit«*iortt* letel
                                                   <
                                                   I  3* rr  oU ««i4«r
                                                   t
                                                   1
                                                                                                                     Caatk 5 Jan after exposure.  long
                                                                                                                     cfeond ciangea typical of acate
                                                                                                                    Bimi KiicicB:  mini:  tims
                                                                                                                    IOI6S; mil;  BU1TB B1I1KBS;  gRtt,
                                                                                                                    FCISOHI6:  iitusniii ITIDSFBHSS:
                                                                                                                    lioit»Tic»:  ccctrpirioiu.  MIIBIIS;
                                                                                                                    CltitBB:  HTatS; iffTOPSIIS
                                                               I
                                                               I  Local, P.I.
                                                               I  Jarivalla, i.e.
                                                               I  Jones, 3.B.
                                                               I  sough, j.
                                                               I  rale, t.T,

                                                               I lancet 2(81aTJ :205
                                                               I
                                                               I

                                                              I
                                                              I
                                                              I
                                                              I
                                                              I
                                                              I
                                                              I
    J731
    OClB*
               InialttKu
a) 60
b) as
O 7*
a) 0.015-0.365 nij/lir
b) 0.012-0.T19 OJ/kr
c) 0.002-0.ISt ia/ar
a) 0.077 aq/hr
b) 0.047 ag/br
c) 0.030 «g/hr
Geoeetric
                                                                                                                                         («»t (dilated
 I
 I at lesUeata at
 I a real
 f t) BesUeit* of Brussels (less
 I Fcllaved tr«a)
I c)  teslieats of Charl«roi  (ceatral

I lie** resldects Uffervd ftot
  Caarleroi fp(0.01) tat tram Iraaeals
                                                                                                                   Malta* sabjccts >SO rr old,
                                                                                                                              f tft« m»mf ar«as 2S
                                                                                                                           itniTS; let; BLOOD rusai;
                                                                                                                  ff»I«!; eitSIJS; IIIB; SIECOEI;
                                                                                                                  eitiis; me; mtsTRiu BBISSIO»S;
                                                                                                                  IfDHST>Ilt fCtLBTIOI; POP0tlTIOI
  I Eoela, B.I.
  I l«o»erT», S.S.
  ( Bucket, J-P
  I Bermard, t.
  I 1981
  I  ZaTiroacutal  3esearch
  I  24:117-130
  I
  I
  <

  I
  I
  I
  I
 I
 I
 I
 I
.1	
I 3732
  trrla*
                                                               a.»-28.5 oo/l
                                                                                          tot glr«»
                                                                                                                  t*po»ti  6-30
                                                                                                                  ItNTS; BIOOO: ID1ETS; VSIIE; H
                                                                                                                  tin  ifUTSiS: lusnsnix anfcss:
                                                                                                                  cionti: occvFHiorii BHMBS: amu
                                                                                                    f  IHqraa, L.
                                                                                                    I  Mttsaoo, S.

                                                                                                    t  Pariica io BedlciM
                                                                                                    I  Btolwjf 2«(1):1»-2«

-------
7MO-70-I
ca
It* 10.OB,  IE 850 C, SI la«0 C, TP 10 M Eg at 983 C
1ISSII

3733
Blood

















373*
Blood,
seras


















3735
Braia














373*
eraatli







EIPOSOK BOOM
























































Inhalation








UllRlCtL
OETBOD



















us



















us















Fin








niBSS
OP C1SES



















a) 260
b] 2«0



















3















1








MICE

«) lot aiTat
b) lot , set.
laagtk of reside DC* , aarital and
•coaoale at at as, occupation, noaber
el ckildran. sacking habits, ht, at.
la kacd-eatar araa. aloaificaat
Itctaasa ia ayperteasion, ice
ataoraalitiaa, aad krperKieaaia.
iiisis: aissciBij isnis:
CItDlOTiSClnM DISBUSS;
nrrnnsioi; BLOOD SEIVB;
CCBPlSlTITt ITILDIII01E: CIDBIOi;
CltCHS; CtlCllni; IMBWS;
iieiism: IBOSPEOIOOS; pmissioa;
saotoi: TIIC-. BIOICCBSOIHIOI:
CII1S1K *lt»
a) elotraa pallliD«, 11 saaplvs.
ecctetclmt of rariation (CT) »0.«
l\ Catdat* oicleis, 13 aaaplas, CT
3S. 9*
c) Pataaan. 12 caaplas. CT 33. Of
1} Salstaatia nlgra. S saapl«, CT
*1.t«
«t Cerebtal cort«i, 17 saaples, CT
43.0f
f) Eippooaapas, 13 saaplei, CT M.6I

IttgpST saatles

CIEIB5U COitITi SE1SUSMMI RSIBODS;
citctOB; cetitij IEOI; Riieiizsi;
nail: IOTOPSIIS
t«Tal9 aftar «Tponc« to aerosols of
c>a,lk dust froa blackboard erasers a
fiactloa of cartlcla alia. latiaatcd
trca grapk. Tidal volaaa ol about
9CO c« a aid respicatorr frequoncr of
1! cycles/alt aaiataiand dtrlag
taapliag tlaa.
EtllTB: BKCinz; C1LCIOB; CBLOKIITB:
lilt: koTOionrt: ixiosraiEE:
KFUnCE

Cootlmrn, t.
Baltoa, I.I.
larria, B.J.
Giles, R.I.
trovii, 3.K.
Taraer, TC.L.
»111iinso». I.e.
Tortar, J.O.
Barrie, M.I.H.
BcRaf. G.S.
roeock. s.j.
isao
British Badical Joarnal
2<1(<232):11-14





Biaraabaee, R.I.
riaischaan, I.I
Oann. 3.

1975
lAnca-t
1(1»1«) tlOOI-1016














Goldberg. 1.3.
111m, l!
1981
Clinical Caeaistrj
27(»):5t2-5»«











Des*«daleer. S.S.
Riackaater, J.I.

Environmental Science
and techaoloqi
9 (10): 9 71-972



(BEIT PIBE)

-------
Caleian
7MO-70-2
Ca
Itl 40.06, BP 850 C. BP 1440 C, TP 10 •• Hg at 983 C
                                                                                      (COHTUOED)




























1

IISSUE | EIPOSOBE BOUTE I 1IJI.TTIC11 HtJBEIB | BalGE BE1I | SBBEBll IBF08H1TIOB I SEFEBBICE
1 BETBOD OF OSES 1 1 1
1 1 1 1
II II
3737 Inhalation FIXE 1 | lot given 20. 1 ng 1 « 1 sanpled at rate of 1 1/nin, 2-10 1 Ikselsson, K.E.
Breath | | iln after burning * arc velding rods. | Desaedeleer, G.G.
1 I 1 Johansson, T.B.
1 1 I University physics shop, Florida I Winchester, J. B.
Ill 1 1976
1 1 I ftCBIDl: HOtTS; BHEaTH; C11CIUB; | annals of Occupations
i | CCIOXIRE: CBBOKOB: COPPES: IBOI; I Hygiene 19:225-238
| | IIJD; MIGIIISE; IICKEL; POT JS Sltm; I
j I soxFOR; tiTHiuB; viHiDiOH; ZIBC: IIB (
| | PCUDTIOI; FUSES; IBDOSTBUL |
| | MiOSPBEBIS: TRICE EIEBEHTS |
1 1 1
1 1 1
3738 US a) 31 1 a) lot given a) 397 ppa I a) learning disabled I Pihl, B.C.
Bair b) 22 I b) lot given 1 b) 311 ppa i t} Controls I Parkes, B.
1 1 1 1»77
| I 1 learning disabled and nornal 3rd and I Science
1 I I 4th grale students in Canada. 1 198(4313) :204- 206
1 1
1 1
1 1
1 1 1

1 1
1 1
1 1
1 3739 i 1
|

1
I
1

I
1
1
1
I

1
I
1

1

1


lair 1 1
1 1

1 1
1 1
1 1
1 1
1
1
1

1
1

1

1
f



3740
Bair











3741












Spinal
cord

























































n












X-ray spectron


































1









a) 42
b) 40











7
12






















a) 63-1501 ng/g
b) 77-2068 «g/g











a) 29.9-94.1 ug/g
b) 17.2-66.3 ig/g
ry *t












1 1
| ClICXHR; R1GIESIOR; POTASSIDB; I
1 seems; CIOBIDB; COBU.T; COPPEH: i
| HOB; IBID; BaRGalSSE; ZIBC; |
| CBBOBIOB; LITBIUB; HE8C!JBIi BET US: |
I BUB; CHIIBBF.I; CllaOa I
1 1
1 1
1 Beviev. 2* representative I Chittleborough, G.
1 tre-analysis treatments are 1 1930
I tabnlated. The feasibility of a I Science of tbe Total
1 holistic, so-nash policy for hair | Environment 14:53-75
1 analysis is outlined and sgpported. I
1 1
I BEVIES; TB1CE ElESEITS: SUB; |
I ltSTBU.Il; RIaStTBEBEBT SEIBCDS; |
I HTHS: PBOIIHS; COBP1B1TITE |
I MllOlTIOBS; IIOBIBOB; 1ETIBOII; I
1 iBsiiic; itaiiTB; BEOaiiz: CIDHIOB; i
1 CIICIBI: CBICBIII: CBBOHIUB; COBILT; I
1 CCPPEB: sunns: GEBBIIIOB: GOLD; i
1 ICSIIE; IBOI; IIITBIIVI; LE1T; |
I E1SIESI0B; BIBGalESE: BESCHBI; I
1 ICLISOEIHB: iicKiL: {BOSPBOBOS: i
1 fOTISSIOl: EOBIDIUB; SILEIIUB; I
1 SIIICOI; SIITEB; SODIOB; SIBCITTOS: |
1 SOIFDB: TIB: TirinaB: TDIGSTEB; i
I me; ZHCOIIU8 i
i i
l i
a) 26« ng/g 1 a) Controls I Ryan, O.E.
b) 210 ug/g | b) Stltiple cclerosls patients | Holibecher, J.
ledians 1 Sanples fron 7 scalp sites in each I staart, D.C.
1 cnbject. 1 1978
I I Clinical Chenistrv
I C1I1DI; IDniS; CEBIB11 BEBVOnS | 24 (1 1) : 1996-2000
1 £1SIEB 3ISE1SES: H1IB: ILHSIIOB: |
I IBCSIIE: cucnm; CBLOBIBE; COPEEB: i
I ecio; IODIIE; niGiiiSE: BETHS; i
I SfLEIIfl; SIITEB; SCDI8B; SBimB; |
1 I1«10I05I; rllC 1
1 1
1 1
a) 54.7 * or - 27.9 1 a) Botor Deacon disease patients I Rarlander, B.B.
ttg/g | b) Controls 1 Patten, B.R.
b) 35.0 » or - 15. 1 I ventral horn tissve. aatopsy 1 1979
ug/g 1 1 Innals of leorology
Dry lit 1 Patients died of nyotrophic lateral I *(1):21-2«
1 sclerosis aad progressive sescnlar I
1 atrophy, nan age, 58.6 » or - 13.1 I
1 ?i< Control: died of various 1
1 diseases at (0.9 » or - 11.1 yr. I
1 1
1 1MIS: 10DL1S: aOTOPSISS; 1
| IMSOimCULIB DISUSES; SIII1L COBO; \
\ cioiccvimtaTioi: citcimi: cotpii; \
1 IICI*. ItlCs IMCanSf. ISTlUt \
\ siitirm IIK i

-------
CirtxM tatcacUocid*  II CI)
tataait. tctucUoro-  n CI)
««-23-S
CC1*
!I 153.8*.  IP -21.6 C, BP 76.8 C. TP 100 » Bg  »t  21.0 C
TISSUE
37*2
Brtatk


KfOSOtt BODTI



IHITTICU
BITBOD
ec-is


BDBBM
OF ClSES
54 (397


BMSI
lot aivea


U1E
1.4 ag/1


GIBIB1L IBFOllallCB
S*amr<4 at 25 c aid 7SO » Hg
M.~n occnxitace
Icier a«d «p«t oae-Sigaa Halts 0.»3
aid *.< 14/1
Bealtar. 19-35 ir old, noeaaoklEK],
•eta* blieka aad eaaeailaas.
Cklcaga. 11. Bigldlr controlled
aipcriaaatal ooidltloas.
flllTB; 11CCB01S; ILLIWIS; 1D01TS;
CtlOtliniD BYDBOCHBO1S; TOUTILI
ciGiiic coipcinos: BUITB HIZIIBS;
fO'BHTIOl IIPOSOBI: OBBll 1BI13
BEKBEBCt
ECOtOSXIDSkl. B. K.
Brnneav. G.I.
C< Belli, H.J.
1979
Joacaal of inalfttcal
Toilcology 3:225-23*


 Ctlill
CI
It*  132.90SI. IP 28-5 C, BP 70S C.  TP  1 •• tg at 27S C. 10 ai Ig it 373 C
TISSUE
37*3
«UMT





















HPOSTOE BOW!























iiumcu
BET BOD
»






















main
or C»SBS
i) e
b| S
c| 12




















utei
a) 0.006-D.058 tg/y
i) D.OO5-0.064 ag/q
C) 0.009-3.057 ltq/9
fet »t


















<»BIT
Bill
a) O.OU ug/j
b) 0.01T 09/9
c) 0.021 ng/9
let vt
Heliats

















PUSH
emut iiraiiiTioi
a| coitrolt
b) (atfccr itoop I
cl Mt»«r gicap It

t«c«»*«d rtfiaerr ud ia«lt«c
norkecs. ag«a 55-76 ji, exposed to
k»*T ««tal« 1-3 decalo. Tiie
tctiee* cetimeBt and death 0-1. S yr
1> gro«p I aid 2-19 TC, gcoa; II.
ccatmlB. a«es 13-72 re, vio lived SO
la fro* «« factotr. S««d«m.
S»m: CICITIKS; KIDIETS; LITE1;
IOISS; COBMUTXT* BTlltHTIOIS;
IlDDSnial 8ISIEII: BStSOBIinT
HIBODS; iniBOIl; 1BSZIIC; ClDIHIi
CISIHB; CBtCBIDI; COB11T; COFPBB;
coin: isoi! imiiiva; ins;
tllCtlBSE; IIJCUH: tOtlSDimH;
EtOSPBOtDS; IVBIDtnB; SC1IDIIB;
smmi; sitTEE: TIB; toiesni;
me: Bum Huuas; inmsniu
fLktlS; SBttTEES; TBUDIIOI

BIHBBIC!
Brine. 0.
locdberg. G.
Wester, P.O.
1980
Scle*oe of the total
En»lroua«»t 16:11-35

















                                                                                                                                                                                      LJ

-------
       Cuimi
       YUO-W-2
       C*
       Itt  1JJ.M5«, n  28.S C.  BP 70S C. T) 1 u If *t 179 C.  10 n  89  «t  371  C
                                                                                             {COITHIIZII}
iissoi mosaic tom iniRicu
BSTSOD
37M U
Unr




t

1
1
1
I |
II 1
1 1 1
1 1 1

l
1





t 1

17*$ I U
laaa t
1
I

1
1
I
1 1
( 1 1
1 1
1 1
1 t
1 1

I
1






•OBBEI
or cuss
a) 8
bj 9
et n






















8
9
11





















1 »MI

a) 0.01»-0.05Z aoyg
b) < 0.0010-0.0*1 U9/9
Cj < 0. J00«-t.0«3 t«/a
««t «




















|
a) 0.005-0. CM *g/g
b) 0.00*-9.0*8 09/9
c) 0. 007-0. flSO aoyj
tat *t




















8ii i t eiiiuL inratUTioi
i
a) 0.018 oj/9 1 it Control*
•1 0.3065 m/g | tj loriar «til> 1-3 d«eai«*. 1t*»
batMm r«tirta»»t aa4 teat* 0-I.S yr
ia qzoap I aid 2*19 yx« orovp 11.
1 cos won, aaas «l-72 yc, «lo 11 wa SO
1 H froi tit factory. s»«d««.
1
I SfiDCi; ciaitsis: ciirtrs; HTM;
IflSS: CO5P1MTII! mUUIIOIS;
IICOSIBIH ireitii; ncison«»T
tltSCBS; jRIBOIT; UStWIC; Clinvc
ctsmii CBIOBHTB; couii: COPFII:
eoic: ito«: imitm: aits
flieimC; fUCBBT; SOLIBDHOB;
EMSMOCVSs IQtlffrVB; SCJVOXDBj
sntnov: sum; TCI: THKSTEI;
tiic; HIITI HJiisrs: iiiosisni
SliftSt SBltltBS; TCLtffSIOR

I nnnict
{
1 Br«a, 9.
1 lordoar*. S.
t vvvtar^ P.O.
1 1»8«
1 sct«oc« of taa Total
1 ZaTlroBMBt 16:13-35
1
rr 1

50 |
1
1
1
1
1
1
1
1
1
1
1
1
1
i
1
1 Brag*. 0.
I lardbara,. C.
1 »«st«r, P.O.
1 1480
1 sci«c* of the fatal
i EorlroBMit 16:13-35
1
1
1
1
1
1
t
1
1
1
1
1
1
1
1
|
1
1
Cklord
C19-M-CI8
II *0*.8, tt 175 C «t 2 »
                                   1110(8-5)  u «9 »t 25 C
l rrsiM i
l i
37*6
•Ilk







l
1
t
(TfOSPXt MtOTC
laowtioa








t
i
iraimcu
SffUOQ
oc





t

t
t

iraszt
OF CUSS
a] 21
b) 24
c) »S
i) »5






1
1
t
IJfSI
a) 4-4.150 ppa
b) 0-0.733 ppa
c) 0-0.723 ppa
4) lot 

I
t
\
1 , . . -

-------
Chlorine
77S2-SO-S
Cl
Itt 39.753. SP -101 C. tt -3«.OS C.  TP  «800  u  Bg «t 20 C. 1 •• Bg «t -123 C
tlSSBS

37»7
Breath








37*a
freatk









37*9
lair

















3750
Bair












ixfosms MUTE

lakalatioe









Inhalation











































1IUTTICU
SRBOD
rat









HIE





























»













man
OF CASKS
1









1





























«l 23
b| 19
e| «2
d) 14
•t 26
f) »0








11KB

8-0.005 ig/cn •









let given





























a) 230-5(20 ««/9
b) 20-910 ««ya
e) 20-5620 og/f
d) 230-2710 og/g
•) 20-2120 Bg/g
f) 20-2710 ag/g








BUI

lot giren









29.8 na





























a) 10«0 ug/a
b) 360 Ig/9
c) €90 og/9
4) 1570 ng/g
et 780 sg/g
f) 1050 ag/g
sedians







CIBIlll IBFOIB1TIOB

Ut«r aitoiotiT* Pb htlld* Mro«ol
•iposvre. !«*•!• a Cvaction of
TKtlel* sis«. B«tiHt«d fre* graph.
Tidal TOllM of aboit 900 CB » and
respiratory frcvnacy of 15
CTCl«s/ili aal«t>l>«4 dariag 10-aia
saifliiq tia«.
aiiiti: Btcnn; ciicxgR; cnotiiB;
tut: igionmTS: WBOSJBJBB;
tllTICILaTZS
e 1 »aapl«4 at rata of 1 1/iia, 2-10
lia at t«i timing » arc *«lliag rods.

0>l*«raltT tkyslcs »hop. rlorlfta

tUBXBt; 1E11TS; BBBIIB; Caicloa;
CBLOBIBBi CBBORIVBi COPPEls IBOB;
mo: BiBeiBisB; ncdi: KTCISSIDB:
SBLFBi; tninoa; TMIDIOB; TIBC; in
KJIIBTIOl: TUBES; IBDBSTIIll
ItBOSPBBBBS; TH»C« BIBBEilS
B«*i*«. 2* r«pr«*ntatiT«
Fr«-aaalTsi< tr«at*«>ts ar«
tafeilated. Ike fuilbi.li.tT of «
kellitlc, ao-«a>h roller for hair
analysis is cot lined and supported.
itrixB; TBICI BiiatiTS: BIIB;
HSnUIt: BI1SOBBEBR BETBOOS;
IITILS; PBOIIIBS; COBV1B1TITI
HHBITIOBS; UBBIBOB; 1BTIBOBT;
IBSIBICJ B1BIOB; BROBin; CIEBIOB;
CI1CIIB; CBICBIBB: CBBOBIOB; COBU.I;
ccppSB; sutjDB: GSBBIBIVI; ooio:
ICCIBt; IBOB; HBTBIIUBJ LB1E;
BISIBSIDS; BUCIBESB: BEBCOBI:
tetiBotna; BICKHS PBOSPBOHDS;
MiissnB: BBBionia: SBLKBIOB;
SXIICOB; SHVEB; SODUJBJ SIBCHTWH;
SIIFOB; TIB; TITIBIBB; 30BCS1EB:
MIC: UBCCBIOB
a) Bale controls
t) Tonal* eottrols
c) 111 ccntrols
1) Bal« saltiple sclerosis patient*
•) F«n«l« ssltlpla sclerosis patients
f) 111 Btltlrls sclerosis patieits
Staple* fros 7 scalp sites IB eack
(ifcject
ClBIDl; 1DBIIS: CIBTBU. BIBfOOS
fisTEB oisBists: BIIB: UOBIBBB:
MOBtBB; CIICIOB: CBLOBIBE; COFFEB;
cciii xooiBi; BiaciBisi; HBTILS;
StlEBIOB; SIITSE; SCSIOB; S01FDB;
IIBIOIOB; IIBC
HHSZEC!

Oesaedeleer, 6.6.
Vinekester, J.».

EBTlronwntal Science
and Teebnology
9(10»:971-»72




Ikselssoi. K.B.
Desaedeleer. G.s.
Jokasssoa* T. B.
Winchester. J.B.
197«
Inuls of Occopatioail
Hygiene 19:225-238




Cklttleboroagk. C.
1980
Science of the Total
Environment 1«:S3-75















Byan. D.E.
Bolibecher. J.
Stuart. B.C.
1978
Clinical Ckenlstry
2«(11):199C-2000









-------
    Cfclcrototi |t CI)
    Catkua. trlchloio- n  CI)
    «7-«S-3
    C-S-C13
    » m. 39, H -63.5 c,  re  100  •• ig it  10. • c
















1
1

1
1
r












TISSUE EXfbsm BOVII i 11*11*101
I BCTBCB
i
37SI OC/BS
treat*





1
r
i
i
i i
r i
i i
i i
3751 1 ee-BS
Breath i







1
1
1

l
1
i
1 TO a sra
1 or casts
i
8



|
f
|
1







s* fr
f
1 minis; ciictttiT» BIDIOCIBBOM:
i CBIO1IBX OBEWXC COWOIMDS!
| CBlCflOSBaTZBifKrj FKFO9XVS COBPOVUkS?
1 isriiB: uccfois; THIS: (Dints
i

23.3 ag/1 r Manrat at IS c «Bd 7CO •• Bg
SaOMtrlc I «2- Tf oci«rMBc»
I lerar «a *PT*r OM-slgaa lialta 7.»
j ait 73.7 >g/l
1
1 B«alt*T> 18-35 yr olfl, •oB«aklag.
I «t«a Hack* aad ea>casia».
1 Ciieaqa, 11. ligidl; coitiollvd
| «p«clMatal co*dltlo».
1
| E1IHB; ItCCEOIS; II1IBOIS; IDOLTS;
| CBLCSlrlTID eTDBOClEtOIS; TOHII1I
| CESlnc COiKITIDS; iniTI BlllBDS;
( 3IBMHICI; BETIEOUSS; gllaMlRBS;
J fOMLITIOB timSDBE; nB» IBB1S
1
IMBSCTCI


Cookl*, J.P-
CMP, ;.J.
Mich. B.S.
1»7S
lrchlr«» of
EDTlrouotal Bealtk
30 (2) : 240-295








xrotoaimrtl, B.K.
Braaeaa, S, «.
O'Balll, B. a.
197S
Jotciwl at laalytieal
Toilcalogr 33 225-23 «










              l » CD
9 . W-5«oaeBi>lwu-S.7.131W] -Irlei-J-M,
«»-97-a
CS7-J<»-0
•1 381.62. H 8«-85 c
I TIJSM
1

1 3753
I Blood,
scrva






















SirOSBlE BOffTJ







i
i

















l iiiiTiieii
1 giriov
1
f

Caipetltiw
ttndiog



1
1
1
















OP CISSS

15
























| BM6I
1
-1 - -
i
a] Pat qlrca
t>) rot glrei
cj (at giren
3) lot g-lta
e) Bat jl»«a
1) Bat giT«n
gj Rot glvu
h] lot jtiei

















1 Kit 1 fitlEIK I»rOSUTIOB
1
1
a] 2T «c - 3 atffi. 1 rt 2S-trdrciTTlt««i» D fi«tatollt«) ,
b] 28 «r - 1 94/Bl 1 15 CfcLldno lltb blool =t of 1D-24
c( 23 or - 1 og/al I o?/r*£tuia 9
1 U-etiboUMJ, cUldrca is a]
1 f) 1.25~dUTdroxr>it»l« K/ etlllrea
1 In W
I gl 1,J5-diliTdror7Tlts«io D, children
1 1* c|
1 i) 1,2S>4tiTdroxrTitMla D. ehHdr««
1 i» e| <(t«c ckalatiaa tterapj.
f
I 1-5 71 old«. BT
1
{ itii: f!Ti.m D; cinoiEr: in TOIK;
1 IlOCt; COBPtllTITE (niniTIOIS: BIOOO
1 SMOB; SETieciisB; smsoiiiis:
1 EIOBOIICBOItClIClrSBOlS
1
ftrtxaci

9039k J.7.
Ctaner. 3-1-
a««»tn, I.
D«Ioca, B.T,
!ab>ff€T, I.E.
1980
Vttv BoglaoA JoorD41 of
HclidBa
302 [2«» r1T2a-iui

















-------
ciroaloa
7MO-«7-3
Ct
Itl SI.M6, tt 1990 C, BP 2«*2  C,  TI> 1 u 89 at 1«f6 C,  to •• Bg at 1ft«0 c
11SSM

37!»
t«I«Ul
ala»d












3755
lort*
















3756
lorta












3757
Blood,
plaaaa








BIPOSBBB BODIE



























































11UTTICU
HFTBOD
us














u

















us
























BOBBBB
or cans
> i
> 5













3

















•1 1
l>» 5























S1BGB

) lot glna
) 31.5-156 ag/a »«t .t













Boa* tetcetti

















a} ik>t givu
to) 8.2-13. C «g/g vat »t























BUI

a) 1530 ng/g wt vt
b) lot gina













Boa* d«t*et«d

















a) 221 ng/g »«t *t
b) tot gl»««























GCICB11 IIFOIUTIOI

a) lockvr
b| Controls

JiCaneM ioTk«r, 65 Tr all, at
ctiout* TrcdDClnq plant foe 30 Tr.
tl«a of nxillaty ani lug canc«r.
Cntcols, a««« !S-7« jr old.

Jltal: IDIPOSE TISSII: UHIa; BOII
IIIMI; Will; CISEBttLSB; CMItBOB-.
IIIIR5: IlflEJ LOTES; SBSCIIS;
(iicms; SHI: cnonaii COPPIB;
situs: me; IIDJSTBIJI. piiiis;
1IB1HT10I; COCTO1TIOI11 B4IIBOS;
fctraiiioi IIPOSOM
lal«*

Iroa a aroip of 61 Mtopsivs.
tctcmic aealctl «xa»lutloM. Japan.
Bills, nao aq« ao. 6 T'* T«aal«s,
t«ai ag« 37.* yr.

MICE ZlKIItB: IVTOPSIIS; JIPJI:
iimmu: USEIIC: CUEIIB: COBM.T;
CBtOHHS: COfPBl; IBOt; B1BCDBI;
1ICHJB; B1S1ISHH: DUeallSB;
IDHDIHa: 1RIROIT; SCimiDB;
siiinni: inuioa; TIIIDJUB; UK;
CC1I; BSOSIH; lITtB: RIBHISi
emnni: cnnn&tti; asm; IOSCIM;
fiiCBiis; spun: miss; iant:
B (TILS ; COIFllMIft ETHBIIIOIS; SKI:
ICtHSIC BTG1CI1B
a) torku
b) Coitcols

Ja(aa«M « octet, «5 TT old. at
cktout* (lodocinq plant fox 30 TT.
tl«d of aaxlllary aid lug caaecc.
Cntcoli, ao«A 59-71 jl old.

J1P1»; 1DI70SZ TISSUI; 10IT1; BOII
S1BBO«: tllll; CISBBELtOB; CBIBtBn;
IIBIBTS; illlS: I, DIGS; RDSC1ZS;
IIBCBIU: StlB: CBBOilDB; COSPEB:
EtTUS; UK; IBDBSTBIU PIWTSj
lISKktlOl; CCCOPITIOIIL B12MD3:
tCPOTlTIOI EIPOSOB!
ItTla«. Protlsas IB risk analysis of
e»e*r 1* Bl aid Ct ladmtrj at*
pc««t«d. various coapoanda at*
citvd (kick cana« eaacar ID practical
ciponc* sltMtiou. n« iMd for
4oa* nfistxatioa Is «apkasii«d.
ICBIH; CIBCIBOB1S: BLOOD PtlS-IJ;
I«IS; IIDBSnUI HtSIBK; SETtBB;
CBBomi: anus.- BICKCI; CBBCIIOGBI;
IIOnSTItlil KBOSVEBBBS; IBIVSTBIES;
CCCIPITIOIlt B1KIBDS; IBOFI1SRS
BSJIIBBCB

BTOdo* K.
SlXDki, S.
InrnTa, B.
Beshiioka, !C.
ueo
IBtcraatioaal Icchivts
of ooeapational and
InTitouABtal Bealtk
46:141-150






YokaH, B.
Swnki-lasitBoto, B.
laano. B.
Tecal. B.
1980
lrckl»«s of
BBTiroBMBtal Baaltk
35(1):3«-B«










Brodo. B.
Sozoki, S.
r«aia, B.
(•abixuka, B.
1*80
IntxraatlODal irchiTcs
of OccapatioBal aad
BBTicoBBeatal Eaalth
«6:1<1-150






•orsetb, f.
1*90
Journal of Toxicology
and BBTicoBMBtal
Bulth «(5/6|! 12 W-1227






(IBM PIS!)

-------
Ckniiu
Itt 51. WS.  Sf 1999 C, 3T I6»2 C. W 1 a* 8e at  1«1« C. 10 mm go. at 1MO C
                                                                                  (comma)





















nssn


3TSi
•ena'















mostii mm i IIUKXCU
1 frUOD
l
US




1
1





amin aiaac sij»
or cisss

a) 260 a) lot ei.*en a) 0.012 * or - 0.002
b) 2CO b) vot 9i*ea ao/7
b) 0.0*3 * or - O.OOT
ag/l









1
1
1
1

1
1
1
1
379* t US a) 1
laaa r W '
•arroa 1
^
i i
i i
i i
i
i
i i









ci i»u. nramxioi unurci


a| (aaeii CItr. JU. aard-nater area Bieraaba«.a. B.I.
b) U>MS cttT. *>, aaft-*atec area nelackaaa. l.T
Siaiificaitli kt^ker lent (r<0.01) Baaa, 3.
it »ft~«tex area.. Inold, J.
UTS
IS «md 10 reeldeate aatcked far age laacet
(aeaa a«ea 37 aad 3T.7 rr|. eex. 1(|eia)s10M-loU
lea«tb of realdeac*. aarltal ud
eceaoetc etetas, oecapetioa, aeabec
cf ekUdrea, «aakla« kaMtcv kt, »t.
I* karl-aater area, etoaiflcaat
irereaee la fcrvertMicioB, ICC
araorealltie*. aad krpererlceala.
R1VSIS; BYSSOVBXf AOVtTSi
CIltlOTMCMII PISIISIS;
• CPf*TnSZOa. BIOCD SBKOB;
CCIMUIin CTIIUTIOMJ C*»ntl;
cticnii ciionofl: HTBHTBJ
B1B1ISIBB; HOStBMOISl KlllJSIinrs
SCBIOT: tnci BiotceanuTtci:
cittrraa ntn


) lot flrea a) 51.3 nj/g a) tarter Irada. X.
k) lot alrea b) 22.* aa/a | >| Caatrola s«nkt. s.
*et rt 1 tmtni*, 1.
t | JapaaeM eercar, 85 fr old, at »«»W»o*«, I.
t 1 caraeate trolacijae plaat tex 10 yr. 1580
I | tied of eadllarr aad laae caacer. lateraatloaal IrcUves
| crttcele. i««d S»-7* fr «la- «t OceapxtloBal aad.
1 A)TlroaM*tal Bealtk
Jin»: tDirosi TISSBC; ioHa; Ban
(iiian nuit cnnutDB; CIIJBOTB:
l f i UBiBTSj art*} utesi aosctis;
f 1 1 *»»cMis; am; cnanaBi ccrpsi;
1 1 MTI1S; tllC; IIBIBMIU. FtatTS;
1 II IBBIUirOlf CCCtrfATXOVll BAX4EDS:
1 1 t 1 CCFOUTIO* tmsni
1 1 11
1 til
I 3760 1 in f la) *ne detected a) Vane detected a) Rale*, cerebraa, 8 mbfcct*
1 Irata 1 1
II 1
1
1
1
1
I
r
l







i
f
t
l
i
f
1

















I b) ftwe detected 1 »| teae detected t) feaale*. ceratne, « nb^eets
1 c) me detected 1 cl Baae detected c) Balea, eacebtllna, c aatjecti
1 d) loae detected d) >oae detected J) teeale*. cerebellaa. • avbjecte
|
1 ftoa a arm of ft *otop«l«».
1 1 (omsle aedleal exaelutioM. Jffta.
I | la]e«, aeaa ao* M.t Tr. rtnles.
) 1 aeaa ao« 3T.< rr.
J
1 II1C1 tLBBIIU; inorsitS; «HI;
I utRna: Msnic; cumntt; COBUT:
t CEfOBHTB| COPm; IBOV; BBBCKBT*
I IICIUB: iicftsiaii tuetitsi:
l mime; iniBoir; scuvrirf;
i Jiinimij tnmiB; nuviai; &K;
l sotr: noitBii imi; nrans;
l cttinni; cfianui: axiit: TOSCIES:
I F1KIII5J SIUBI; LDIGS; 10 lilt
I BtlllSt COBflUTITB >TUIltIC*3; SIX;
i music Bmcrii
i
«:t«J-!5O
















































Totaaa, V.
santl-laaaaoto, B.
tent, v.
1910
lrefci*as of
rnriron»eat»l Eealth
35(11 :3«-aa



































                                                                                                                                                                                 oo

-------
ciroulM
7MOM7-3
CX
Itf SI.99C.  IT 1900 C, BJ- 2CI2 C,  It  1 mm ty at HIS C, 10 •• 19 at 1WO C
                                                                                    (coiTUoiD)
IISSBI

37C1
Bra la














37(2
Bxaath








3763
Bair








37«a
lair

















IUOSBH toon

















laaalatioa






































IBaLRICll
B2TBO0
US















mi









us




























BUBIEl
or cuis
















1









a) 31
bl 22



























•JICI

a) 1st glra
b) lot glT«>
e) lot gink
d) lot glr»












lot gl»*a









a) lot given
b) lot give*



























•Ml

a) 62.1 »g/g
bj St. 5 ug/j
e) 5&.0 >g/g
d) 19.5 ug/g
lut «t











9C.« ag









a) 0.25 ppa
b) 0.09 ppa



























SEIIUl ZITOIIITIOI

a) lorter - o*c*bcaa (teaporal)
fc| lorter - cenbra* (occipital]
<| lort«r - e«r*b*lla>
d) Coatrol - e*c*brua |fxo*tal lob*)

Jataa*aa vorkar. 65 yr old, at
cbcoaat* frodncinq plaat for 30 Tr.
tied of aaxillacj aad Imng caac«r. 5
cntrola. aqu* !»-78 yr.
J UII; llirOSI T1SSDB; 10BTI: BCIS
Biiioi: n»ii: cniBEiioa; cniEni;
me BETS; inn: HISS; BISCLES;
Tiiciiist »iis cnonoi: CCFPII;
BIMIS; IltC; I1BBSTK11 PlliTS;
IBlltlTIOl; CCCVI1TIOIIL B1I1IDS:
icttUTtai tirosots
* 1 aaaaltd at rat* of 1 Vain. 2-10
ata after baralag * arc nlding rods.

Bal»«r»lty ptyulca akop. Florida
ItOIIDIi aEBlTS; BIIWB; CUCIOI;
ccioiiR; ciwiios: eoppii: iioi:
HID; laicmss: sscsns Miassim:
SUPBl; TItllin: VillOIOg; CIIC; III
iciioTioi; ions; XISDSTBIU
niospints: inci miERS
a) learulag disabled
t) Coitroli

l«araiaq ditibled aad aoraal 3rd aad
ata grad* *tad*ats la Canada.
ClICIBl: •aCIBSIDI: (OI1SS1OB!
SCCHa; CatHTOB; COBU1; CQ»SS;
iioi: ii»; iiioinsi; me;
CIIOINI: tltlTOB; BIB CUB I; IBTUS;
•Hi: cniDKi: ciiua
le*l«. 2* x*pr*s*atatln
tt*-aaal7tla tr*at**ata ar*
tatalat*d. Ik* feasibility of a
kellstle, ae**asa policy for lair
«»»lyii» la emtlt**d aat a«pport*d.
ItTIEl; TIKI IlialBTS; Ball;
KSISllIl! lUSOUini BITHOOS;
mus: iioiins; COIMUTITI
imnnoBS; iioiimn: mnoiT;
llSIIICi BlltOB; BSOIIBEt CIDBIOBJ
ciicim; ceicint; cnoBivi; coaiiT:
. «.t.
Da>a*d*l**r, 6.G.
Johansaoa, T.B.
*lack*«t*r. J.I.
laaal* of Occupational
Bfglu* 19:225-238




Pihl, 1.0.
Parkas. I.
1977
Science
1«B(*313):20«-206





Chlttlebocoagh. 6.
19BO
Sclano* of the Total
Z»lreiM>t Hi 53-75















(I1R PISE)

-------
Clrealia
1MO-4T-3
CC
itt si. Me. n 1*00 c.  tr 2««2 c.
                                  T» 1 » l« it 1»!6 C, 10 •• lg at 18«0 C
                                                                                     (COVflKFED)
1
1
1
1
1
1
HSSBI MPOSBBS BOOTB
37«S
Balr
1
1
1
f
1
1
l
BFTBOD

37(6 f M
••art |
1 f
1 1
1 1
1 1
< t
1 1
1 f
1 / 1
i l 1
I01BSI
or cis

•) 8
w *
1 1 *
3767 | U | a) 22
fitter 1 1 b) 3
r i
i i i
i i i
i i t
1J1GI

a) lot gives
b) Bone detect**1
lot gives,
(one detected
iiai i eiitut iiroiBMioi i IBRIBICB
i i
i i
I 1 rsvlev of iiorld literature o* tie I Jaailas, D.s.
I aecMnlatlra and blocoBeestratloa of I 19T9
I selected toxic trace seta!* la tnus 1 E>a-«00/*-7*-0*9, It*
1 ktlr aid sells «al a tier sessallu 1 pp.
1 bait, far, atil*, clavs asd tools. I
I Jaiolated by geographic area, 1
1 »t)ects, sex, *ge, expomte 1
1 gradiest. asalrae* la pp», and I
I aatbaritv free over 400 reference*. 1
1 t
1 MIICI: iistiuia: cauoa; czniu 1
i itznci; tncns HBSIB BIST; n* t
| tZallES; SCm IBXBICl; SOOTBJ1ST 1
1 ISI1; BIXTFD KTK9OI; OII9I9 ST»BS; I
1 iui; mis; BETin; irriBOtr: l
I MSS1IC; BOtCI; CIBBI3S: CBtOBIOBJ |
I CCtJttj CCPFU; LStDl IBBCB1T; 1
I iiciEt; sntiiOR: Hi; Tinnraa: UB i
l fciivrioi; inni pojonnois: i
I HOlCCIBBIltlOI; BIOIIDIC1IOBS; IIIO I
1 iciiDiioi: reroLaiioi titosvtt: ttttt i
1 FOtionoi : IBICB MiBBns: IETIU i
i i
l i
a) 0.07 + or - 0.12 1 al tales 1 Tvxata. B.
ag/g (vet «t) I t) resales 1 Saz*kl-*as»oto, 1.
b) lone detected I 1 >e»o, «.
1 rros a Troop of 61 aatopsles, t Tersl, B.
1 (orsaslc sedlcal exaslaatloas, Japan. 1 1*10
1 Bales, eeaa age M. C r'* resales, t archive* of
1 seat age 37.4 rr. { tirironaestal Bealth
1 1 35(1|:3*-M
1 tsaci ziBBtiis; iraopsiss: »»ai; I
i aiontra; IISMIC: cuutas coiui; i
1 CtBOBTOd; CCfPEK; IBOir; MBCmi; 1
I iiEim; sieiismi; uieansE; i
1 MMDIJI: JIHBOBI: SCaiDIOB; I
1 Sllttttrt; TIIalTOB; MUDIDB; ZIBC; I
1 SOtD: BBOBI1Z; IITBS; (I9BBTS; I
1 CIIEBSOB; ClBtBEIIBB; BEtBT; BOSdlS: I
1 FJUCBHS; SI1BZI; HISS; JOBH: I
I BZtalS; COBP1B1TITB BTlltJkllCBS; 5SX; I
1 fCBEISIC tit Kill |
1, 1
1 1
a) 0.09 « or - 0.3* I ») Bale I Tatava, B.
«9/g (vet vt) 1 t) resale I Sozakl-Tamsoto, B.
b) lone detected I I Isano, K.
1 Iroa a groaf of 41 avtopsles* 1 Teral, fl.
1 forensic sedlcal exaslsatloss, Japan. I 1980
1 Bales, seaa age »0.« ji. resales, t arculres of
1 seas age 37.* rr* 1 Envlronseatal Healta
1 r 3SO):3«-««
l iiacz nEBtiTS: taropsiES; japi»: i
1 110BH7B; JBSJBICi CaOBIOB; COBU.I.- |
1 CBBCBIN; CCtfEB; I BOB; REBCtJBT: 1
I IBOIOB; BaGBESXVB; U161BSSB; 1
1 ismiiB: IITIBOBT: SCIIDIDB.- i
I sniima-. uiaiioB; TI«»DID«: ziic; i
1 CC1D; BBOBIll: UTE1: KIOBETS; |
1 CZIZnUB; CZBEBB110B: BBaBt; BOSCLES: 1
1 EIICBI15; SFIBBI: 10I3S; 10M1; |
1 sniLS: coB?uatiTB ETalvaTiois; SEX; i
1 ICBZISIC RltlCHS I
1 t
lisn MOB)
                                                                                                                                                                                        oo
                                                                                                                                                                                        o

-------
 CftiMln
 7««0-«7-3
Cr
J» S1.99C. IP  1900  C,  BP 2642 C. TP  1 » Eg at  1616 C, 10 •• Bg It  18*0 C
rrssiri

SS,











3769
Kidney



















3770
tine


















3771
liver












ixposni sotnt




































































iBiiTiicit
RfTBOD
115











11




















Bl



















iU













tmtst
or cases
) i
} 5











a) B
bl 20



















a) 8
*i 7


















M 1
b) 5












la KB

) lot given
I 3.«-22.2 og/g vet it











a) < 0.003-0.069 eg/g
b) < 0.003-1. 14 »g/g
»et «t


















a) Bot giien
b] lone detected


















a) Bot gi^en
b» W.7-38.7 ng/g vet at












Bill | SEBZML IBPOBBITIOB

) 128 ng/g net tt I t) rocker
b) Hot given | t) Control*
I Japanese torier, *5 yr old, at
1 catenate producing plant for 30 yr.
1 tied of aazlllary and long cancer.
I ccntcola. aged SS-71 yr old.
1
t Jltll: 1DIMSJ TISSOI; aOSTl: lOIS
t B1BHB; BtllB; CIBmUIJB: CEEBESDS;
| BIOI1T3; I1TEB: 10IGS; aDSCIZS;
I HBCIXU: sin; CBIOBIDS: ecipnt
1 IBBlllTIOB; CCCDPHIOB11 B131EBS;
| KTOUTIOI IIPOSD1I
1
a) lot given I a) Coatroli
b) Bot given t t) Voxkeis. gronp* I aad II
1
1 Itceased refinery and aaelter
1 vexkecs. age* 55-76 rr, exposed to
1 l«a»y aetala 1-3 decades, tine
I Ei yr old.
1
I OIP»: aDiPoss Tjssoz; lOEii; BOB:
1 BIBtOV; atllB; CIFS3ELIDB; CIFEEBOB;
I «mms: uytsj iJBss: auscus:
1 I1BCHE1S; SKIS; CBBOHlnR; CCIPSB;
I irtiLS: 21 »c; IRDEISIHIU pxiirs;
1 IBBlLlTIOB; CCCW11I01IU, E1ZUDS;
1 ECPOTHTOB 1JPOSOEE
imBZICZ

3Yo3o» K*
Smkl, S.
leshixaka, X.
I960
International lreU.Te>
of Occupational and
ZBTironnental Health
a*: HI-ISO





Erene, D.
Vordberg, 6.
tester, P.O.
1980
Science of the Total
Znvironnent 1*: 13-35















Tnleava, a.
Saznkl-Iasanoto, S.
llano, I.
Teral, a.
1980
Irchlree of
EiTixonnental Health
3S(1):3«-«4












BfOdo, E.
Sllrti, S.
rirtya, 9.
1930
laternfttioul Itcairea
of Occupational and
Zniironaental health
46" 141—150






(BEIT PaPI)
                                                                                                                                                                                               00

-------
Ckroaln
1MO-47-3
Cr
»tt 51.»»«. 1* 1950 C, BP 2M2 C, TP  1 » Hg at  16U C«  10 •• lg It 18«0 C
ussti
3772
liMT
1
1
3773
l«*e
1
1
1
1
1
1
1
1
1
1
I 3771
1 l«»9
1
1
!
1
ixrosni tom


1
1
1

i
i
i
I
i
i
I
i
I
i
JkULTtlCll
BETB0D
U
u
us
(

mm
or Cisia
a) »
b) 21
al 3
» ^

MMI iu> i ctBiBit iiroiiiiioi i nrxsncs
i i
i i
i i
a) < 0.003-0.11 »s/q a) lot gir« I a) Cntrola | Btu«. I.
b) < 0.003-0.23 »a/g b| lot aim I 1) (ork*». groip* I a«J u ( BordlMta, G.
l«t »t I | v«it«r. I.e.
I ttcMMl rcilMrr a»8 *Mlt*x | 1930
I nrkvrc, •<)•• 5S-7t jr. •xpow« to 1 Scl*ac« of tk* Total
1 k»*T Mtal* 1-3 tecatu. Tt» | nviconMtt 16:13-35
I bltvMi »tit*Mat aad teatk 0-1.5 Tr I
1 It gro»p I ai< 2-1* jr. qroir II. j
I Ccitrols, ag«« (3-72 yt, »ko Una 50 1
1 >• fro* tk« fictotf. Sv«a««. |
I SIIBII; C»)inS; CIMITS; tlTSB; |
I IBieS; C08PH1TITB WHOUIOIS; 1
1 IltDSnill HGIXIS; SMStJElSMT I
I i iRiooi: iRiJoir; iBsiiic; usnua; i
I i CZSIBI: cnonoR; coatu: cant*-, t
1 1 eOlB; noi; tHTMigi; IJIDJ |
t I MKlltSI: BttCBlI; SOITBBJIOB; |
I | IMSPBOIVS; IBBIBIITSJ SOirlOB; I
i i attnm: mnts ni; roiesnit i
1 i tncj SJJITB HUjiri: neosniM i
i i CHITS: sntTos; numva t
i i i
it (
«) 0.27-1.2 09/9 |Mt .t) | a) O.SS » or - 0.»6 | a) 8al« | Takan, 1.
I Ma* d«t«A«d 1 ag/g (««t nt) I t) MiaUa | Saxakl-Ia«aoto, 9.
1 b] Ion* tetoetcd 1 ( laaao. I.
1 1 tto» a qcoap of *1 aatopcix, I t«ral, 8.
1 1 loraaslc ndtcal naataatiou, Japac. I 1980
1 | lalm. Maa a«a «0.f Tr. r«Ml«a, { lrcfcir«a of
1 I Maa a«« 37. « rr. 1 Enriroaacittl Bcaltb
1 1 1 35<1):3«-*a
i i tiict ninns: utopsns; JIP>I; i
1 i iinnmi: iisinc; cionoi; COBUT: i
i i cnonrai; ccmu IM»; »tcnT; i
1 1 IIDIOI; RieitSIHRj IM6*II»: |
I | BOBMIUS; tinaOIT! SCMPID9: I
i i siunoi; tmnvi; nuoiiu: me: i
1 1 etlD; BlOilll; tITUt IIDIttS: |
l i ciMBius; CEtnin.ua: BUIT; HVSCIBS; i
1 I FUCtflS; Sfirai; IITKS; IOH1; |
I i Bims: ccBfiwTire naioniois: ssi; i
1 i fonsic MticiM i
i i i
l i J 	 - ~
») lot 9! TOT | a) 7100 ng/g I a| Iork«r. rl««t «r;tr lob« ( Byodo. K.
t) lot gi»«i 1 b) «S30 »g/» | t) (ork«r, ri^at aidU* lob* 1 Sntrti, s.
c) lot aiTai | .c) C1C mg/g I c) forkcr, right lo««r lob* | rtriya, I.
9) 96.9-293 »g/j | i) lot gir«B | «) controls, right iep*r lob* I BtsHinU, K.
»> 204-2»1 ag/g I e) lot glraa I *| coatcolc, rtgbt alJdl* lob* I 1980
C) 19.3-13* aa/g | fl lot giTeB I f) Coitrols, cigkt lo««r lob* 1 Ktcnatioaal IrcklTM
l*t «t | (at »t | | of occupational ana
t I Jaraaaa* lorter, t5 Tr old. at | EBTiroamtal B*altb
1 1 ckroaat* trciocla? plaat for 30 jr. 1 *«:1lt-tSO
1 1 ti«a at MXtillaiT aai long ca>«r. I
1 1 ccatrol*, «g«a 5«-7l ri oil. 1
1 1 1
1 i Jim; iDiPosi Tissnj; IOETI: sets i
1 i BiiBoa; BBHI; cnntuw; crasspoB; i
l i mtiEiS; IITEB: LDIGS; HBSCIIS: i
1 l iiicstis; SKI; cnonoB; cotrsi; i
1 l prtiis: Hie; IIDDSIIIU. PlirtS; i
1 1 IIBWIIICl: CCCVPlTIOItl 11I1BDS; |
1 1 fOPTClTIOl HPOSni |
1 1 1
(HIT PIG I)
                                                                                                                                                                                         oo

-------
Ciroila*
7«0-«7-3
Cl
Itf SI.996,
            ir IMO c. tr  2C«2 c, rr  i u 89 *t i«ic c,  to ••  (9 at  isao c
                                                                                    (COBTIVDED)
IJSSOB
37TS
1.19
377«
Mlk
3TTT
Ba»Cl«
37W
.•••el*
•iiosnc Bom




IIUTTXCU
ECTBOB
n
us
u
us
nrnzt
or CISBS
•I a
b) 9
C) 11

al «
b) *
1
I1ICE
•) 0.025-0.72 «9/iJ
b| 0.0*7-1.75 »9/9
c) O.OSI-H «9/9
*«t wt
•) 0.23-0. *« «9/*l
b) 0. ta-O.a; ag/lai
c) 0.19-0.t9 >9/il
4) 0.1 3-0.*. * ag/J«i
a) lot 9l»«
»J tot «ir«»
lot gins
•MB i «mm iiroiBiiioE
i
i
i
•1 O.M2 19/9 I «) COBtrol*
b) 0.32 »9/9 | t> tartars, 9ro«p« I «•« II
O 0.14 tg/g |
I«t *t | r«C«UWlt«t
MAltll | 9«* (3-72 yi, «ko li»wl 50
I »• froi tb« teetoiT. S»«i«i.
1 inon; cigttms: tioins-. ivrn-.
t mesj CORMIHITE Emuiiois;
I niasniit ITSI«K! raisotum
I iRWDS; iniioiT: usnic; CIDBVB:
1 ctsni; cBiotru: ccuur: corpii;
i Kit'. licit iimim: LS»D;
1 tiietnsi; mcgiTi niiSDinm;
1 itonioifs: IQBIDIOII scimira:
1 SHima.: SILTZBt III; TDiSStllJ
1 me; mill aituis: IIDOSTHII
I tuitsj S9HIEBS; mtntzni
i
l
») 0.«3 » «r - 0.13 | t) 10 (otktti, «-1t toy* IscUtlon
•q/il 1 b) 10 Ufaiti. 8-H days oil
b) 0.27 * or - 0.10 I c) 5 lottoT*. «7-S4 a»r» laetatloa
ag/aay 1 <) 5 ialut*. (7-5* tay* old
e) 0.39 4 or - 0.21 I
wj/al 1 Batlmn a«4 twic br«»«t-I«4 imlaats
4) 0.2C «• or - 0.1* 1 It M*lu«.
•9/aay J
1 em: uctHiOBi muw; cnoiini:
i ttius; coarumTx irunmcisi
I IlflBTS
1
a) 0.»» » or - 0.10 I >) l*l*a
09/9 (nt »t) | t) ?••*!••
b) 0.07 » or - O.ia |
•9/9 t»*t vtj 1 Iioi a qiomr at «1 »topxUi.
I fot«Klc H41cal •xailutioal, Japai.
1 (aim. Mai *.g» »0.t yr. T«aaln.
1 ••«• a«« 37. a yr.
1
I HIM ttsBiBis; inomss; JIMI:
1 iioiiws; iisnic; cuaim: COBU.T;
I CltOBIOl; CCimi ItOlj tllCUST;
1 IigiOH; B1SBISIOB1 I1BU1ISI:
1 BUIDIVB; klTIBOIT; SC1BOIOB;
1 sncBini; utiiiBB: TiBioioB: znc;
1 SCID: BBO»I1; tlfBB; SIDIITS;
I ctteanB; cnnxuti: BEUI; BHSCLBS;
1 flBCIt»; SP1EM; 101BS; lOBtl;
1 BRUS; C01FIUTITK ETaLIlTICBS: SIX;
1 fCtllSIC BEBICIBI
1
61.3 19/9 *«t »t |
1
1 dafaa«M «oi1r«c. 65 yc olfl. at
1 cicoaat* [xc4nclB9 VUat for 30 yc.
1 tl«d of (axillary »ai luq canc«c.
1 JIf>«: »DIPOSK TISSUE; MITli BCRS
t qum; niiBi cniBinoo; CESBESOS;
1 RISERS: LlTtt; IHBeS; ROSC1ES;
1 flfCHlS; SXII; CBIOBIgR; COPtll;
1 BITltS; IIK: IlDBSIlIIi fllRS;
1 JBBI11TIOE; CCCWIIIOIIL BH1BD3;
1 tCtQUSIOl tlMSm
1
unMsttt
Braa«, D.
•orSbarg, e.
B«tK, P.O.
1*10
Sci«BC» of tl« Total
EBTlroBMit 16:13-35
r«»p«l»U«a. J.
Tmori, E.
1980
Kerlcaa Joamal of
Cliaical ttttrltlom
33:22*9-2302
Takava, B.
snvkl-Tamaoto, B.
luno, X.
I«r«i, B.
1980
Ircktres of
CaTlroauntal Baalth
35<1|i3C-M
ByoAo, S.
Sncki. S.
rarvya. B.
iMshiivka. R.
1980
latarsational iccUvas
of Oocvpatloaal and
tarttoneital Bulth
«6:iai-iso
lint MSE) "' • '• 	
                                                                                                                                                                                         CO

-------
     Ctroaioa
     7«40-<7-3
     Ct
     »« M.99&, IF 1900 C. » 2645 <. n 1  n  B» at ISIS C, M aa la. at UlO C
                                                                                       (com i HID)
        HSSSJ
                           BOVTI
                                      iitirricti
                                        iznci
     nnaa
   or ctsis
                                                                                                                              GZHUI mosunoi
       377*
       ••11
                                                               I
                                                               t I r«rt« of world literature 100;  111
                                                                                                                  |  lOItOTrOI; JII811 FCPOHriOISf
                                                                                                                  I  IIOICCUIDIITIDI;  BrOMOIClIOES; U«D
                                                                                                                  I  ICIITTIOI; TCfOiJTICl EXFCStBZ; FJIBS
                                                                                                                              inci  ELmns; snus
                                                                                        1»7»

                                                                                      1 PP-
                                                                                      I
                                                                                      I
                                                                                      f
                                                                                      1

                                                                                      I
                                                                                      I
                                                                                               , D.I.
   I 3190
   I call
   I
   I
   I
  I
a) 9
t) 11
«0t
lot
  6.77 * or - 3.99
P"
i)  4.23 t or - 1.25
I i) laaan
» 1) B»
I left ttnib
I Ilso relieved:
I ctbec eleaeats
I
I  Eealtbr 20-«C rr olo<
                                                                               tnooa  larcla of JO
                                                                       SKI:  nits; iMiri! uonnra;
                                                             | IRMOIT;  1I5BIIC; BUIDIi ClSHlrB;
                                                             l cuciBB; cssnu; caBosiuB: CCBIIT.-
                                                             l ccpreB;  etsttaatt SOLO; iso»; IEID;
                                                             I B16I«SIO«: BIIG1KSI:  BSBC0BI;
                                                             I  IClTIDtltia; IICKU; COT1SSIDI:
                                                             I  JOBIBI1H; 5HMIBS: SI1ICOI; SI1TSB;
I Kaaabrocki.  E.t.
I Ksnabrocii,  J.t.
  Sreco,  3.

  Oexter.  r.T.
I  Brar, S.S.
                                                                                                                                                         »«130B, D.B.
                                                                                                                                                         Boon. c.z.
                                                                                                                           UK;
                                                                                                                                                       I Science of tbe Total
                                                                                                                                                       I iBTlronaent 13:131-1*0
                                                                                                                                                       t
                                                                                                                                                       I
                                                                                                                                                       I
                                                                                                                                                       I
                                                                                                                                                       I
                                                                                                                                                                                      00
I 3781
I Pxoctfts
t
           a)  lot fir*>
           t)  foaa detect«d
                       a)  O.fl» + or - O.It
                       "9/1  <»«t »t)
                       t|  ratra dettcttl
                    I
                    I •] Bales
                    I tt feules
                    I
                    I Froi a vr«ap of  61
                   I forensic ndical aiaalaatiooa, Japan.
                   I galas,  aeaa  ao« 40.6 it.  Feiales,
                   r ie»»  aqa 37.* ri.
                   I
                   l ntci niKiiTs: motszssi jititi
                   t IXCBIlffl; tlSEHC:  CIO HOB;  CO HIT;
                   I CB1CII7B; COPPIB: IBOB;  BIBCOBT:
                   I xitm: !nairsim;  aimaisx;
                    	      IIItBOIt!  XUDlUSi
                              iituim:  TiuoiOB;  znc:
                   I GC1D; 5BOS1BIJ  LITBBj HDBIIS;
                                                                                                                fllCBtlS; Slim;  LOfSS;  aCITa:
                                                                                                                IttUS: CCIFIMT1TE  HILTHIICSS; SIX;
                                                                                                                icinsic
                                                                                                             -I-
                                      I
                                      I Takaira,  a.
                                      I SazaU-Tasasato, a.
                                      I laaao, s.
                                      I T-eral, B.
                                    ,  |  1*30
                                      I IreklTes of
                                      I tmlton»eBt»l aealtb
                                      I 3S(1):3i-*«
                                      I
                                      I

                                      I
                                      I
3782
faaeta
                                                              •.1-28.0 ng/g «at at
                                                                                                              I
                                                                                                              I  CottoH
                                                                                                                lq«« 5«-7« jr.
                                                                                                              I JIPH; allFOSE TlSSUt;  iOlll; SO»I
                                                                                                              | Bl«10»: 8X1II; Cl»tE!L10B;  C1BSBBOR:
                                                                                                               I i TOUTS: LUn: LUKGE-.  nasciis;
                                                                                                               I tnci»i; ssi»: CBEOBTUR: cafizi:
                                                                                                               I EllalS; tUC; HOTS1SIU. tlaltS;
                                                                                                                11B»1»TI01; CCCDfUIQIal. B1ZUIS;
                                                                                                                            ItPOSOTt
                                                                                                  I  fjodo,  I.
                                                                                                  1  5«otl, S.
                                                                                                  I  rnrnra, >.
                                                                                                  I  itesblztta.  X.
                                                                                                  I  1980
                                                                                                  I  Iitatnitioul
                                                                                                  I  of Oceopatioaal «a6
                                                                                                  I  tBTltoiaaettl  Haaltb
                                                                                                  \  »*-.1»1-«0
                                                                                                  I
                                                                                                  I
                                                                                                 „»

-------
Ctroalaa
7««fl-»7-J
Cr
Itl 51.996,
            IP TWO C.  BP 26*2 C, TP 1 •• Hg at 1«1< C. 10 •• Bg at 18*0 C
                                                                                     (com* mot
TISSUE

3783
Tkazyax













37«»
Stla













3785
Svleea

















3786
He In*













EIPOSalB BOOtE


















































Inhalation














1IUTTXCU.
nnoD
us














us














u


















us














nun
or cisss
I i
) 1













a) i
b) i













a) 9
b| «

















22














BUGE

• ) lot gi»*n
b) let given













a) lot gi«en
b) lot gii«n













a) lone detected
b) lone detected

















a) lot siren
b) lot gl»en
C) l«t gl«B












IUI

a) 96.7 ag/g
b) 27.9 ig/g
let »t












a) 104 14/9
b) 14,3 ag/
Ret «t












a) Ion* detected
b| lone detected.

















a) S. 3 » or - 3.7
nq/g cceatinln*
b| 33.3 * or - 6.9
uq/g cr«atl«ioe
c) 2«.S * or - 12.5
m/g creatliioe









GIIII1L MFOB11IIOI

a) vorkec
t) Controls

Japaivae vetker, 65 yr old, at
chxout* ccodncing plant Cor 30 Tr.
tied of lailllary aid long cancer.
Ccntrols, agio: 59-78 rr.

JIPII; aDIPOSE TISSUE; lOitl; 1CIS
I1BIOI; Stilt; cntlELlQI; CHIIlraa;
(loins: tTTEB: Liiss: Bosciis;
tllCBtlS; SKII; CBtOBIUll; CCCPE1:
eitllS; CIIC; XIB1STBIU BIIBTS:
iiiiUTici; cccnpiTiom BICIBDS;
tcrotMioi IIPOSHBB
a) lotket
b| Coatrela

3at*n«3e «or)wc. K it old. at
c trout* tEotaeing plant for 30 jr.
tied of •aiillacy knd Ing cancer.
central!, aged 59-78 fr old.

J1CII; aDIFOSE TISSUE; 10STI; BOHE
H1B80I; JE1I1; CEBIBELLUl; CIBEEBIH;
HOIITS; IlftB; LDieS; BOSCLIS;
E1ICIM3; SHI; CBtOBIOB; CCEPII:
Buns: site; inosniu, PIMTS;
iiBjiaTioi; cccopiTioiai aisiivs;
ECPOUTIOI 1TPOSOBS
a) tal«a
t\ r*»i«s

fro i a groaf of 61 aitopaiea.
forensic aadlcal eiaalnatioiu, Japan.
Bales, neea age «0.6 TC. r«aalea.
aeaa aq* 37. • TC.

ItlCI !LEBE«1S; tOTOPSIES; OtPtI;
II.OMOTS; IBsmc; CUHint; COBUT;
cciesni; CCFPEI: iao»; BssctRt:
lltlOE; SIOIISIDB; aafGtIISt;
1IBIDI»; 1ITIBOIT; SCMDlnB;
siLnii*: TIIUTJH: miDinB: Jl«t:
e»D; BMBIBE; 1ITEB; HDI1TS;
CIEEBlm; CttlBELLia: IU1T: SOSCIBS;
ciicstts; sptisi; ines; losu;
B1T11S; COHPU1TITE ETtLOlTICIS: SIX:
PCBEISIC RltlCtlE
a) Stalalees steel veldvcs, ctposed
«.« 11
b) lrao«c«4 steel welders, exposed
1.0 11
c) Carolina platers, exposed 8.9 yr

Italians, lean age 40 yr, taak
•aiafactnrlng

Increase la teta-qlecuronlftasa.
Ttatelnarea, and lysoxyaarla.
1HII; IDOITS; KIDIET DISE1SIS;
Dim; BIOKCTHDIATIOI ; THUS;
IIDTOTBUI PCILUTIOI; IHODSTBIIL
IIEICII!; eiROMTtfll: BET11S
tEFEBZICB

ByolO. t.
Soi»ki, S.
Fanya, B.
Beshtxata. E.
HSU
latecnatloaal trchlves
of Occupational and
Eavlcoaicatal Bern It k
•6:1*1-150






Byodo, E.
S«akl, S.
Fnrgya, B.
B«shlmka. K.
1180
International Irchires
of Oceapatlanal and
EBTlronsaatal Baalth
46:141-150






Takava, S.
Sui»ki-Ia»naot.o, S.
llano, K.
Teral. B.
1980
IrcbLies of
Enriroiiantal Health
35(1):3«-4«











flattl, i.
Caratorta, 1.
Pedronl. c.
EOTgfci, a.
elaroll. c.
Pranchini, I.
1979
International archives
of Ocevpatloaal and
Enlronwntal Bealtk
13:123-133




(MIT P»SB) 	
                                                                                                                                                                                            oo

-------
  Ctroslia
  7»a.O-a7-3
  Ci
  Itl  51.996.  «P 1999 C.  BP 2C*2 C. TP 1 aa Hg «t 1616 C.  10  mm  Ij  at  18*0  C
                                                                                        (COETIEOED)
1ISSBI
3787
vrlae







BIPOSBBB BOOTS









aiunxcu
BETBOO









EUBBZX
or casss









I»6B









IEIB









GEIEB1L IEFOIIHIOB
levin. Protleas in risk analysis of
caacec la 11 and Cr iadastry are
(reseated. Varloas coapoeiids' axe
cited wkicb CMS* caiccr in practical
«ipomr« *iti«tioas. Ifc« o««d for
tea* cealstcitloa 1* •apkaalzei.
icivii; ciiciioms; BLOOD raisii:
«EII!; IIBISItlal BT6IBBE; IBTln:
CEIOnnii IIU1S; IICCZL; C1BCIIOO!»;
iioosTBiii iisosentsist IWCOSTBIES;
cccoriTtoiii Blums: IEOPIISBS
BIFBBSBCB
Beca«t!i. T.
1980
Joarul of Tozicolagr
and BaTlroaaeatal
Health «(S/C|: 12 W-1227





CbZT«Otll«  (8 CI) (TIB)
ctrfMtlle r>»aq3(S12o9j l  (9 ci)
1JOO1-29-5
B10-09-312.3Sq
II 282
f TIS5VB
1
1
I 370ft
I £u?
I

|







1 3789
1 tmmq







f EIPOSOU BOOtE
1
l
1
I
|


















i
i iBiimcu
SETBOO
E9











KB








| BVBBIK
I OP C1SSS
1
1











*








SIB6B

a)
5.8ll« (I* 7| -l.'xtO (1*8)
fltwn/9
t>)
1.0z10{Z»8)-2.7z10(Z<-8)
fllwn/9
Dry rt





lot glrea








SB1B

a) 1.071 10(1*8)
flbara/f
b) 1.6l10(I»8)
elbers/g
Dry "t







10 fiber* or
farraginous
bodleo/saiple







GEIIFaL I»FOBS»TIC» | EEVEBEBCE
1
«
a) analyzed at Oni»«r«ity of Cardiff 1 Sebastian, p.
b) lulynd ty laboratory la Paris I Billon. H.a.
Faraachyaa fioa ease of plcoral I Janson, X.
nsotkelloaa I Bocaaad, G.
tata also for aspklbolc flbecs. | Bigaon, J.
1 1978
10ISS; ISB1SIOS; notUSXSi 1 irehlvca des Baladles
CCRPII1TITE ETUOaTIOBS; BE1S01EBIBT I Professiona«lles, de
BI1BOBS: FBI KB | (tadldi* da Trarail et
1 de Secnrlte sod ale
1 (Carls) 3 9 («-5): 229-2*8
1
1
1C sa spies. la Tiro notification I Jattrand, B.C.
ladlcatal by lacrftase la Sl/Bv ratio, I Goal, J.
s bodies. 1 Jeanrot. I.
1 Sebastian, p.
tatieats. Prance | Bignon, J.
1 1976
SAIC*: tnes: IB TITBO »«11ISIS; IB 1 Sevne rraccalse des
ITO HllTSIS; 15BESTOS; FIBERS | Baladles Besplratolres
1 «. Stppleaeat 2:111-120
1
                                                                                                                                                                                           oo

-------
 Cobalt
tc
Itl sa.9332. n 1*93 C, tt 1100 C, TP 1 M 14 at  1910  C
TXSSfg

37M
loct*
















m,
Blood,
Mtai





















3791
Seala




















EEMSBEI toiTi

































































iHiiTicii
BETBOD
n

















US"























u





















Erases
OF C1SES


















a) 2SO
b) 260












































I1KE

•one detected

















a) lot applicable
b) lot elves






















a) lone detected
b) Cone detected
e) lone detected
d) toae detected

















fttn
RE1I | GEIIBtl IIFOKIlTIOf
j
tone detected 1 (alea
1
1 ftoa a groat of «1 aatopsiec.
1 fetea*lc aedlcal exanlnatiOBB, Japta.
I Btles, aaaa age «0. S Tr. F«aal«*,
1 taaa aae 37. < it.
1
I T1ICI SLEBEBlSt VITOFSIE5; J1P1I;
I altBiira: usnic: CIOBIUB: COBU.I:
I cncBioi; cctpnj IBOI; gncrai;
1 1ICHH; iriSKSIOB: BlIStltSE;
1 lanom: iniiont SOIOIOB:
1 SHEnn; nutim; TIBIBIOB; »K;
1 Ctlt: B»O«IH: LTTSB; KIDIEtSt
I ciimm; cnzBEUAi; BEAST; atiscLis;
1 flBCBEtS; SElIEEj IOIGS; »OH»!
1 1HILJ; COfltUKln nUBMXOIS; SSS;
1 fCBEBSIC BICICIM
1
a) lot detected I a) Kaaaaa City. (3. katl-vater area
b) 0.1«« * oc - 0.026 | b) Kaasaa City. 10. aoft-aater area
•9/1 I IlqaiflcaatlT blgber Krel [P
-- i
a) Hone detected 1 a) Bales, eacabcat, 7 sablecti
b) lone tetectad | 1) Teaalen, cetebcaa, » aablecta
O >one detected I c) Balea, ctraballai, » satjecta
d) lone detected 1 d] Fcaales, caraballaa, « »ab1act»
1
1 f coa a qtott of 61 aatopnlea.
1 taceaaic aedical axanlnatioaa, Japan.
1 Bales, aea* aqe *0.6 it. Fanalw,
1 leaa aoe 3?.* rr.
1
1 itaCE nERtttsj inofSiES; JiPii;
1 iivniit; iisniCi CIPBIOB: COBUT:
< C1ICBIJB: COfPEI] IBOf; BEICII3T:
I I»ITIB: BieiunBi BaieiiKii
1 siiBiivaj tiuiiga; nnoiWi zi«c:
i sctD; swam; irrstj nonis;
I CllEBBVl; CIIEBEU.ni. EEaBt; IVSCLES;
1 viBCTiu; SPUSE: attest town:
| BtTllS; COBPU1TITE ETIUlTICHi $!X;
I FCBEVSIC HItlCIII
1
r PISE)
nri BZECS

Takan, B.
Snialti-IaBtaoto, B.
aaano, E.
fatal. B.
WO
lech Ires of
EBTiEoiMBtal Health
35(1):3t-o










Uecanbaaa, B.I.

DUB. J.
Irnold, J.
M75
lancet
1(W1»):1008-101«

















Takava, I.
SazaU-Ianaoto, B.
leaao. K.
Teral, 1.
19BO
IrchlTaa of
loTlroanantal Health
35 (1) • M~a4












t

                                                                                                                                                                                             00

-------
Ccb.lt
7MO-W-S
Cc
l« 58.9332. » l«»3 C, BP 3100 C, ?P 1 ••  Rg  at  W10  C


















xi5soz

3793
Hir







379«
laic





1
8IPOSDEE BOOTI










IIU.TTXCIL nasn I 11101 RHR
BITHOD OF C1SES
US a) 31
b| 22











a) lot given a) 0, 16 ppn
b) lot given b) 0.23 ppn










1

1
I (
1
GFIZI1L IIPOlaiTIOR

a) learning disabled
I) controls

*tl grade stndenta in Cagnda.
cucioa; B »e SKIDS: POTISSIUH:
SCUM; C1IBIDH; COBilT; COPPBH;
ZECV: LSir; HIVGJSESZ: zzic;
CEBOinti: tiiertu; SJBCOBIT: RZTIU;
B!IB: CBJLCBM; cinot
fieriev* 24 representative
Ece~analrsis treetseats are
tatnlated. the feasibility of a
holistic, no-nash policr foz hair
analrsis is outlined and snpported.

ftTIFI; IEICI B1H JITS; III];
losmtii; ausoiSREtt SMBODS:
| 1 MMIS: PBOlSIRSs COftFlBlTITE
| I
|






I
| t

1 1
t 1
379S | |
Sail t 1
I |

1 i
I |

• i
1 1
I |

• i
• *
1 1 1
I


















































IfllDlTIOVS; ILOHmil; 1RTIROVT:
1ISZ1IC; BIBIOS; BBOSISB; C1MITC:
cuciVR; cncsiRC: CJSOKORJ COIIIT?
ccppfB: cmittr; siBBinoa.- soie;
xcoiit: IBC«: LinsMus: me;
MCHSIOH: austiisi: BSBCOBT:
(CITEBHDR; IICKZI: PHOSEBOBUS;
ECIISSI3I!: BOBIBIOS; SElniOB;
I silica*: si i TIE: SOOIOR: SIBCITIOR:
I stiFDi; in; Tninra: Ta«ssTi»;
1 IJIC; tlBCCIIOT
i
I 1 te*ie« of norld litecatare on the
1 eceninlntion and nloconcentcation of
1 selected toiic trace netals in nnnan
1 talr and nails t*l other nannnlian
1 tnir, f»r, nails, class sad boofs.
1 tstnlsted ti qeoocapklc ar««.
I tubltcts, sei, toe. exposnce
I otadient, analrses in ppn. and
I svtkoritr ttam orer *00 referanees.
1
1 iFtici: i0siiu.ii: ciiioii CMTBU
| MUICl; ZtllCPC: HDDt! E1ST; IN
| iZlUID; SOUTH IRZEIOL; SOOIBE1ST
i is»: Hint niGBOR: OTITIB STITES;
1 RIII: mis; terisw; tiriaofi;
1 iistfic; BO!o«; cioaioii: cfreeflimi;
| CCB1U; COPP1B; LEID; BIBCDBI:
I lICKZt; SZ1ZIIDR; Til: TlIlDlnii lie
| ECHUTIOf; HUH POPBHTIOS;
I eioicmraiiioii BioiiBictToss: ti»D
1 foiinTioi: PCOTiitici sxposffHE; »irrs
| fCUCTIOI; niCt SLKHTS: RR11S
1. 	
BIPZBEBCB

Plbl, B.C.
parkes, 9.
1977
1991*313) :204-20«





Chlttleboroogti. e.
I960
Science of the Total
iDl-iroosant 14:53-75

I
f














enltins, D.«.
179
Pl-SOa/4-79-049. 19*
P-



















                                                                                 (IEXT PiO!)

-------
Cebalt
7MO-*9~«
CC
It! 58.9332. OP 1«93 C. BP 3100 C, TP  1 » Tig at  1910 C
                                                                                      KOITIITOD)
TISSUE

3T9S
Be art
















3797
Kidney
















3199
Kldftef




















XPOSDBS BOBT1



























































iiimicit
RET BOD
Bl

















n

















„





















IDBCEI
OF C1SSS
1 B
b) *
















a) 19
b) 2
















a) 8
M 9
C| 12



















11 KI

) < or - 0.07 ag/q (wet
t|
) lone detected















a) < or » 0.11 Ufl/9 (vet
»t)
b) < or * O.oa ag/9 (vet
•t)














a) 0.00050-0.015 ag/q
t] 0.0007-0.032 ng/g
c) 0.0005-0.0066 09/1
vet vt


















BE»I

I 0.01 » or - 0.03
g/g |vet »t)
) Rone detected















a.) 0.01 * or - 0.03
uq/9 (tret vt)
b) 0.02 * or - 0.03
uq/q (vet vt|














a) O.OOtO nq/q
D) 0.00*1 nq/q
c) 0.0020 tq/q
let vt
leiians

















GEIZIU IIFOBIHIO*

a] Bales
t) rcules

Froi a group of *1 avtopaies.
!oceasic aedical examinations, Japan.
Kales, a«an aoe »O.S jr. leaales.
nan aoe 37. • jr.
Kl« rLEBIIlS- WOKIZS- MPII-
lIIflllDI; 1BSEBTC: CIDHIDH; COBUT;
CHORnn; ccena; iwn; sitcnaT;
IBDIHB; BlGIESIdl; ailOHESI;
tuEinna: imaoiT: scuoina:
EilEiins; Timms: MIIDIOS; zuc;
GCIO: BBOBIII: LITEH; KZDIETSi
CHIBBOB; CEJEBEIMB: HEiBT; igSCLES;
IIICBE1S; SPIIEl; 1VBSS; 10111;
BmiS; CCSP«B1TI»B E»»LtHII01S; Sir;
ECBIISIC REBICII1
a) Rales
t) resales

Pcoa a qrcnp of 61 avtopsies.
forensic *edieal esaainatlOBS. 3apan.
laics, lean aqe *0. 6 jt. Fenales,
actn aqe 31.* TT.
IBtCt dEBEITS; 1HTOPSIZS; JIP1M;
itOBims: iBsiHic; CIDHIOH; COBILT;
cEBcaiia: cciptB; IBOB: BSBCOUT;
HDIBB; 9IGI1SIDB: RllGinSS;
SqEIOIIB; HTIBOII-. SCaSBUlB;
£ii»ii»: TiTUioi: TisiDioa; ziic;
GCL1; BROHIIt; LITIE; KIDIXTS;
ClBtlBM; CltmnLOR: BIltT; BOSC1ES;
EIICBI1S: SPLEEI; IDKGS; lOBIi;
RITUS; COBPULTITE HHOITICHS; 5EI;
fCBIBSIC MtlCIBE
a) Coitcols
t) locket qccap I
c) forkec qcoap II

Kceasei caftnerr and saeltec
•cikera. ages 55-76 yr, exposed to
lea»r tetalg (-3 decades, live
tetwen cetlieient and Aeatb 0-1. 5 yr
in qroap I and 2-19 yr, qroip II.
Ccatrols. aqei »3-T2 yr, «bo lived SO
111 fcoe the factory. Svedea.
EIIDH: ClEirtSS; EIDIBTS; HfES;
tCIGSi COBPJEIIIVE EtlLUlTIOlS;
IIDOSlKlll BTGIEIZ; RilSOBEKnT
atlBODS; 41TIBOII: IBSEIIC; ClDSIiJI;
CI5HJB; cBBcnnB: COBILT; COEPII;
eciD; IBCI: iiBTBiioa; isiB;
IIDGMZSI: 1ISCOBT; f-OITBDIIDB;
iscspHoaas: EoaiBiffB: SCEBDIOB;
stiEnnt; SIITEBJ TIB; TniesiEi;
me: mini BiziBDS; IIDOSIBIII
Il»«TS; SBJITEBS; TEILtlSIOB
EEFEBSiCl

lakava. a.
Suaki-Tasoaoto. B.
IsanOr K.
Ter«i, a.
1980
Archives of
EaTiroaseatal Health
35(1):36-»«










Takava, a.
SuinM-Iasttaoto, a.
tsano, K.
Terai. a.
1980
Irchlres of
EnTiconiental aealth
35(1):3«-4W










Brane, D.
Hocdberqj G.
Jester, P.O.
1980
Science of the total
Envlroasent 16:13-35
















CIEIT P16E)
                                                                                                                                                                                              oo
                                                                                                                                                                                              vo

-------
Cctwlt
Ce
ItB 59,9332, IP t«» C. St 3190 C. It 1 » Ba it 1910 C





















IISSII



379»
llier



















3800
liwr




•
I
I

1

1

t
1
1
1
1
f
I
t


3801




i
1
1







































•

























I
1

















ZlfOSIM






































































touts tiumcu
SCTBOD


n










I

I

I
I
l
i
i
t
11







t
f
l
I

1
t
nsiSt I1BGZ BZII 1 SZlIBll IITOM1TIOB I KSKBgBCB
OF CaSZS | |
< 1
1 1
•) 7 aj 0.02-0.10 m-j/i (wet a) 0.06 * or - 0.03 1 «l Bales | taken, a.
b) 7 rt) ag/-e (»et »t) | l| fviales | samU-Iameoto. B.
b) < or • 0.09 09/9 <••* W 0.05 « or - 0.03 1 1 i«eo, I.
vt) *9/9 ('ot vt) I Fcov a 9rovp of 61 aBtopsles. i Tecal V
| fctensic cedlcal «a*i>atioiis, Jap«o. r H8»
1 e«l«s. ie«a age »0.6 IT. rciales, t Ircilrec of
1 •••» •«• JT-' tr. | I«Tirouutal Bealta
1 { 3S(1):3«-«4
I TItCB ZIHZBTS; ISTOPSIJS; JJP»«; I












a| 8 |l) 0.00050-0.15 nq/q
) 9 | b) 0.001 t-«.0*l 09/9
1 11 |c) 0.0030-0.030 19/4
1 let rt
1


i IIOBIOTS; isszBiCi cwsros: COBU.T: l
I cficmm; coprzi; IBOB; BBBCOBI; i
| IttllB; B1GIISUS; IIBCaBZSBi |
| B«t tOIBS ! aKIBOBTi SCIIBlOfl; (
l snnin: miftonj TIBUIOB; z»c: i
l ««o: BtoBifE: HTM; XIDBZTS; i
| CIIIBBO!: CZIZBBUOB; BEaBI; BBSCltS; |
l tucmsi SPIBSI : IHKS: »cin: i
| SITUS; COIMB1TITE BTUU1IOBS; S»; |
| IO11ISIC tlDICIHE |
< 1
1 1
a) 0.013 ao/g I aj Coitcols I Brtiae, o.
b) 0.012 19/9 I t) lorker grcup I I lordberg, 0.
e) 0.0095 ng/g I c| lorter qregp II I tester, P.O.
let it t 1 1980
.lediaii 1 Ceceased r*f inerr and nelter I Science of the Total
I «ortet«, *?ei 55-74 rr, expowd to | Enrlroniait 16:13-35
1 tea?r tetali 1-3 decides: Tin 1
I teteeei ceUteieit and Jeatfc 0-1.5 yr I
< ir group I »d 2-19 Tt, acovp II. I
| CdtcoK, a9<* 43-72 ft, vho llwd 50 I
1 ki froi tie factory. Sweden. I
1 1
I SfZXZB; ctlatns; riOBns; IITIB; 1
IOICS: COWaUTITE tt»101TIOIS: I
I IBDgSttllL BTfilEBS; (USBBEIZBT I
| | MTBODS; IRIBOIT; USHXC; C19BIII; I
| | C1SIBB; COMMITS: CCMIU COtttH: 1
f | GCID: 1MB: 1MTBK0B; 1X1D; 1
I I | tllUHSf; BHCOBT; BOITBBZiM: I
| | I fEOSPHOlirS; SBSIBIOB: SCKDim; 1
l i i siicnm: SIITZR: TIB; TsmssTH: i
1 1
I

u


1
1



















a) B
b| 9
a 11





















a) 0.000*0-0.013 H9/9
b) 0.00050-0.0*4 *9/9
C) 0.0020-0.0*0 Of/9
»«t M


















ZZIC: 8Z11T8 B1II1DS: IBOIStEril 1
[tins; smtzzsi tumim i
i
O 0.0016 oj/g *) Coatrol* 1 Briue, O.
b) 0.0075 a?/9 t| Vorkec qtcap I l (ordberg, a.
c) O.OOSS ag/g c) forker gtcap II I tester, ?.o.
let rt 1 1980
tediana teceased refinery aid saelter 1 Science of the Total
lockers, ages 55-74 rr, el posed to I ZgYironient 16:13-35
k«IVT netall 1-3 decades, tile 1
tcteeea cetlreient and deatt 0-1.5 yc 1
It oroip I aid 2-19 Tr, groac II. I
cotrols. ages tt-72 rr, «ho llwd SO 1
ki Iron the factorr. Sveden. 1
sstDBi: catiTzts; cioirrs: IITES; i
toias; comiiTin mioitiois: i
IRRODS: UTIBOIIj'lBSIBIC; C1DU1I1: I
cisioB: cBiontiB: COBILT; COFPIB; i
GOtC; IIOK; IIRBIIOB; Lilt); |
iiiemsi; BIBCTBI-. •otTBDima: l
ttOSfWIIIS; IVBIDIDB; SCDDIIB: t
StlNIOB; SltTEt; Til: THIGSTZB; I
IIIC-, BUI7B BalllVS; IBDISTBIU I
n ins : snintts; ttiiasian i
i
(1«M fist)

-------
Ccbllt
Cc
ItV 58.9332.
             IP 1*93 C, BP 3100 C. IT  1 m*  By  at  1910 C
                                                                                       (COrtllOED)
1ISSBI
3*02
Risele
3803
1*11
380*
Pancrea*
xposm som



1B1ITTIC11
BIT BOD
IL
n
n
BIIBBES
or cms
) «
b) 4
a) 9
b) 11
at «
b) 3
I1KI
) lone detected
) < or - 0.13 17/9 (net
t|
a) got given
b) tat 9li««
a) Bom detected
b) Bone detected
1MB | GZIZS1L IBPOIBHIOB
1
1
1
) loaa detected 1 •) Bales
) 0.04 * or - 0.06 1 t) Pennies
aa/« (net ntl 1
I fro* a qrovp of (1 antopsies,
| forensic nedical exaainations, Japan.
j Bales, aeu aoe 40.C jt. Teialas,
1 tea* aoa 31.* yr.
I II1CZ niBIBIS; 1DTOESI1S; JUaB;
| IltlBTBin; IBSEIIC; ClBBlnB; COBILT;
| CIBCnvB; CCEPIB: 1MB; HI1COBI;
| lltrog; SlSHSIOfl; BllGlBBSE;
| IOEIBIOI1; 1B1IROBT; SCIIDIUS;
1 itiEBivi: tziuioi: TiiiDios: zinc:
| CCLD: BBOIIBI: LITtI: HDBITS;
| CIIHBDB; CHEBStlOB; BUST; BUSCltS;
I I11CIE1S; SHISBi IOBGS: 10ITA;
| BIIUS: CORPM4TITS BTUOltlOIS: SSI;
1 tctnsic IICICIRI
1. - 	 	 	 	
a) 0. 07 * oc - 0.04 I •> Bonn
ppa 1 bl B*a
b) 0.0* • or - 0.03 I l«ft thnib
ppa | Ilia r«Ti«««d: knova lava 19 ot 30
Dry »t I ct*« alaaaati
1
I Baaltay 20-«0 ft olds
| ItClTS; SBT; Hits; BBTIXf; H.HBIIOH;
| IITIBOII; MSSBIC; BiSIOB; CtDHtM;
1 ciiciui; cisiOB; CHSOSIBB; COBIIT:
1 ccppn: GZBitiTiB: GOLD; IBOI: IEID;
i msiisina: uBeiBssi; BMCOBT:
| tOlIBBJIOB; BICKIl; POTlSSIOa;
| iOSIDIUB; SZUBIQ9; SH.ICOI; SIITSI;
| SOCIdl: STBQBIIOB; Til; TIlinnB;
1 IIHDIHH: XIBC: iraccsiUB
i
a) loa« datacted I at Bales
b) IOM detected I t) feiale*
1 tio* • groin of «1 aitopaiea,
j focansic aedical e»iimtioic( Japan.
I *
-------
   Cctalt
   Co

   Its  58.9332,  BP 1(93 C, BP 3100 C, TP  1 •• Hg  at 1910 C
                                                                                          (CORIItrXD)
Tissnj
3805
Spleen
















1
SXPOSOBB tomi

















1
1
BET BOO
M


















OF CASES
a) 7
b) •

















MICE
a) < or » 0.05 04/0 (vet
vt)
b) Bone detected
















BEai
a| 0.01 t or - 0.02
<>9/g (vet vt)
b) Hone detected
















6EIEBIL IEFOBB1TIOE
a) Ralu
t) Penales

Iron a groep of *I aatopsies.
forensic eedlcal examinations, Japan.
Bales, wan age so. 6 yr. Fenales,
•can age 37.* rr.

IMCE nsiiEis: inopsiES; JIPIR;
HiBinri; issERic: CIOBIDB: COBILT;
CBBOnlffSj CCFPEBi IBOB; BBECOBT;
ECBIPlil; alTIIOIt; SClBDXDBj
SUEEH3; Tiinioi: TIUDIDI: znc;
SCID; BBOBIV!; LITEB; KIDREIS;
CIBEBBBB; CEBEBEUDB; BEJIBI; RDSCIBS;
FJICBI1S; SP»tKi IUKS; lOETa;
BRais: CCIPIBITITE Efimnios: ssi:
tCBEISIC BEriCIRE

BEFEEEECI
Talwva, i.

ftaano, C.
Terai, K.
1980
archives of
Environmental Health
35(1):36-M











Ccpper
7<«0-5»-8


tt« 63.S«6. BP 1083 C, BP 2S»5 C. TP  1  u Eg at 1«28 C. 10 mm t.g at 18TO C
| TISS0E | EXPOSDtE BODTE | alllTTICIL ( BDBBIB 1 URGE i BE1E 1 GEIEMt IIMBB1TIOI
| | HETBOB OF C1SBS | 1 {
II II
II 1 1
I 3806 I US a) t a) lot 9! Ten 1 a) 0.38 07/9 vet vt I a) lorker
Idrenal | b) S b) 1.12-2.39 ag/g vet vt I b) Rot glren t) controls
glani I 1
1 I Japanese vortec. 65 re old, at
1 j etiolate FCOdociaq plant foe 30 jr.
f 1 1 f tied of •axillary aod lung cancer.
II j | Ccatrols, ^9-78 jr old.
1 i 1
ill I JIFU; JDIPOEB TISSUE: IOBIA; SORE
III! I Bltaoi; BEJII; CfBEaEllVH; CZSEEBHII;
III 1 Kllins; IlfTB; LtTRCS; EUSCLES;
III I EiiCBEis; sin; cnonuB; COFFEE:
I
1
1
i
3807 1 1 1* 2
lorta 1 1
t 1 '




























































1
< or * 2.1 ag/g (vet vt) 1.2 + or - 1.7 ug/g

















(vet vtj
















EIT1LS; !I«C; IIDOSIBUL PtlHTS;
IIMIaTIOl; CCCDPITIOI1L B1ZJS3S:
tcenttTioi tmsniE

tales

Fro • a grogc of 61 aatopsies.
foreosic aedical exallDfttiansr Japan.
Blles^ eean age 40.6 rr. Peiales,
••an aqe 37.* Tr.

1I1CZ EHHITS; aUTOPSISS: JlFtl;
IICBIKD1; ISSEEIC; CIDami; COBUT;
cBEcsrns: CCPPEB: IBOI: IEBCHBT;
IlttVI: B16IESHB; BlIClRISt;
EDilDIDS; HIIHOIT: SCIVOIOB:
SIIEHDI; TIIIEIOI; HMDID5! ZIIC;
«C1D; aiOPIIII; UTEB; KIDR'TS;
CHZB839: CZEEBELLItB: BIIET; BUSCLES;
tllCBtlS; SPIEEI; LUGS; 10BI1;
iniLS: COIP1UTITE ITflOaTIOIS: S!I;
TCIIKSIC HIC1CIIS
BZFEB3ECE



Fjodo, I.
SazoW. s.
Fnrnya, H.
Beshizaka, K.
1»BO
International archives
of Occupational and
Environmental Bealtb
•6:1«1-1SO







Tnkava, S.
Snzoki-Tasuaoto, g.
Inano, S.
Terai, B.
1980
Irckires of
EnTicoDaentsl Health
35(1):36-4«










(HIT PIG!)
                                                                                                                                                                                              VO
                                                                                                                                                                                              ro

-------
per
0-50-8
• 63.516, IP 1083 C, BP 2595 C. TP 1 » Bg at 1628 C, 10 an Bg at 1870 C
(COITIIVZD)
T.ISSI!



3808
aorta















3809
Blood,
semn













3810
Blood.
sersa












3811
Blood.
ceres









IPOSOBE BOOT!




































Ingestion














Ingestion











Murricti
BF/TBOD


US



























































BOBBEB
OF C»SBS


) 1
1 5















28















2


























B1TCS *E1B 1 01 II Ml I1FOB81TIOB
|
1-
1
lot given a| 1.01 ag/g vet »t I a) lorker
0.56-1, »3 ug/g set *t b) lot given 1 M controls
1
I Japanese nortec, S5 vr old. at
j chreeate crodncing plant for 30 yr.
1 tied of saiillart and lung cancer.
1 Controls, 59-71 it old.
1
1 Jifai: iDiposE TISSUE: IOBI*; BOBB
| BlBtOB; IB ill; CIBEBKLIOT; CZBEiBOB;
) K1B1IYS; 1ITES: LSBSS: HHSCIES;






a) lot give*
t) lot given
c) lot given
d) lot given












a) lot given
b) (ot given
c) lot given
d) lot given
e) lot given
f) lot givei
g) lot given




















I MicBtis: SHI; cHBosioa: cansii
1 (IT IIS; me; I1DUSI3IU. PUBTS;
| 1IB1LITIO"; CCCBPITIOIIL BallBDS;
| tCiaUIIOB I1POSOBB
1
1
a) 166.6 t or - 7.95 1 a) 18 pellagiins
a 11 no old. hospital day 1*
f) 108 ag/dl I ft 11 no old, hospital dav 17
g) 105 ag/dl | g) 11 no old, hospital dav *S
1 Cn adnisslon levels belov detection.
1 then given 3.5 eg/dav
I Ccpper-deficieint children.
1
1 C1SE BISTOBIIS; CHIIDSB"; XISBtSES;
t B1IB; COP?IB: BBIILS: 2HC
1
1
1 levlev. Profile of healthy snblects
1 lastline data for deternining change
I it nutritional status from Industrie
I fcoA proceasieg tecfcnigaes.
1
I in 2tniic: »so its: rimst KFMTS;
I I100B 5!BUR; BIIB; KIOIBIS; IIT1B;
1 Bill; «£Vin; OIRS; FOODS; SOUS;
1 vlGRHIOt; CIDBTOB: COPPEB;
] BIBGIVISE; milS; TBtCE E1EBBITS;
| ZIBC
1
IBFIBBBCI



lyodo, K.
Sunk!, 5.
FDrnva, 1.
Beshiznlta, X.
1980
International archives
of Occupational and
Bavironiental Health
a«:1»1-150








Krlshnasacaaci ,
K.t.V.S.
117*
aserlcan Journal of
Clinical Butrition
27:108-111










Bradfield, K.B.
Cordano. 1.
Baertl, 3.
Erahae, G.6.
1980
lancet 2(8190) :3«3-3«









GnthrLe, B.B.
Bobinson, n.r.
1978
>e» Zealand Bedical
Joornal 87(603):3-6







(BEIT P«GE|

-------
Ccppac
74*0-50-8
Cl
It* 6X5*6, BP 1083 C, BP 2595 C. TP  1 ••
                                             at  1628 C.  10 » 89 at 1870 C



















IISSIB

3812
Blood,
seraa










1
|
1
1
1
1




3813
Blood.
sera a

KPOSBBB BOOTS













1
1
1
|







1ULYTIC11 BOa-BIB | BaBGB IBal | GBIIBIL IIPOBBaTIOB
BFTBOD OF CISSS I |
	 1 1
1 1
US a) 2«0 | a) lot given a) 1*4.60 » or - 3.95 | a) Kansas city, KS. hard-vater area
b) 260 | b) lot jivea ag/100 si | t) Kaasas City. SO, (oft-vater area
I b) 172.1* * or - «.7S | Significantly kigker level in
1 ag/100 al I aoft-iater area.
1 1
1 I IS and 8O residents aatened for age
1 1 (aean ages 37 and 37.7 yr). sex,
I | lengtk of resldeao*. narital and
I | econoaic statas. occipation, amber
| | ef cklldrea, saokiag kablta. bt, it.
I 1 IB kard-vat«r area, significant
1 1 increase in hypertension. ECG I
I 1 abnormalities, and kypernrieeaia. 1
1 1 1
| | 111315; BIS5COEI; 1DO1TS; |
| | CatDICTlSCDXll BISE1SBS; |
| | BIPBBtXlSIOl; B1OOD SBBDB; |
I I CC8P1I1TIVB IValUTJOBS: C1DBIVB; I
| | C11CIKB; CfllCBIOH; IITBIOB; I
I I I1SBESID8: PB05PBOBOBS; POT1SSIOB; I
1 I soDins; MIC; BIOICCDIOIITIOB: i
I t DfiiniG IIIIB i
i ii
I i i
IIS a) 15 j a) Bot givea a) 168 » or - 38 I a) Ben, lov tlood pressure i
BIPBBXICB

Blerenbans, fl. 1*
rielscksan. 1.1
Dnnn , J.
arnold, J.
1975
lancet
1(1914)5 1008-1016
















BcKenzie, J.B.
1 b) 17 | b) sot given ag/al I e) lea. kigk blocd pressure | 6atkrle,~ B.B.
1

c) 19 |c) Bot givea b) 1S9 * or - 19 I c) loien. lot blood pressure | Prior. I.a.H.
d) IS 1 d) Bot givea ng/ul I d) loaea. fcigh blood presaare 1
1978
1 c) 179 « or - 30 I Subjects selected by blood pressure I laerican Journal of
1 oq/al 1 rank froa a previous study. I clinical Butrition
1 d) 172 » or - 27 I Iftlaated daily intake, 1.5 ag. 1 31:*22-*28

1
1
1
1
1
1
1
1 1
1
1
1




|
|
1
1
|
1
I
1
1 381* lagestioa 1
1 Blood,
1 saroa |
1 1
1 1
1 1
1 1
1










38 IS
lone
•arrov























1
1
1
1
1
I
I


















....
1 ug/al | f
1 I Fclyaesian residents of Tokelau |
1 Islands, croided conditions, I
1 satsistence ecoaoay. Ben, aeaa age I
1 «! yr. »«an kt 167 ca, nean it 7* kg. 1
| Icnan, sean age 46 yr, nean kt 165 j
j en, lean vt 79 kg. j
1 1
I CCCPIR; ZI1C: BIOOD SBBOB; BAIB; I
1 I | MILS; B1III; I» ZfttllD |
II II 1
II II 1
1 a) 12 I a) Bot givea
1 b) 10
1 c) «














US
d) 7
•) 11
f) 8
g) '
a) 7










«) 1
b) S














b) Bot given
c) Bot given
d) Bot given
e) Bot given
f) lot given
g) not given
h) lot given










a) Bot givea
b) 0.32-1.07 ag/g vet it













..












a) *2.8 ug/dl I a) Baseline data, at age IS * or - 1 Hillnao. L.S.
b) 46.4 ug/dl | (.3 days I Bart in, 1.
e) 58 ng/dl | r) 4 vk | ri
ore. B.
d) 73.6 ug/dl 1 c) 9 vk I 1981
e) 35.3 ug/dl f d) 12 vk I Journal of Pediatrics
f) 40.9 gg/dl I e) Baseline data, at age 17 » or - I 98(2): 311-313
g) 54.3 ng/dl | 7.0 days j
h) 63.9 ng/dl | f) 4 vk |
1 9) 9 vk |
1 «) 12 ik |
1 Creaatare infants fed foraula I
1 ccntaining 1.67 eg/1 cu (a-d) or 0.4 1
1 ag/1 Cu le-k) |
1 1
I nrirrs; BICCD SIBOB: COPPKB; DIETS; i
| BII1IS |
i i













a) 0.82 ag/g vet vt I a) lorker I Byodo, I.
b) lot given I b) Controls I Suzuki. S.
1 1 Furuya. B.
1 Japaaese uorkec, 65 yr old, at 1 Keskiznka. K.
I ceronate) trcdaciag plant for 30 yr. I 1980
1 lied of nazillnry and lung cancer. 1 International ircaives
1 Ccatrols. 99-78 yr old. I of
Occupational and
1 1 SnvironMBtal Health
1 Jlfll; IDIPOS! TISSDB; »OB1a; SO1B | 46:141-150
| B1BBOU; Btlll; CI1BBBL10B; CIBBfSOB; I
| KIIIITS; ll»n; LOIGS; BOSCIZS; |
| (IBCBZaS: SKll: CBtoniTl: COtPIB; |
| BI111S; HBCt 1IDDSTH1L P1HTS; I
1 iiBiiiiioi: cccumioitt BIIUDS; i
1 fCTVUTIOl IIPOSaBK I
^ \







                                                                                                                                                                                          VO

-------
Ccpper
7MO-50-8
C«
III «3.S«6, IP 1083 C, BP 2S95 C, TP  1 aa Sg at  t628 C,  10  •• (9 at 1870 C
                                                                                      (COITIIDSD)
I tISSVZ
1
3816
Brain
3817
train
3118
Iraia
3819
Brail
KFOSB8I toitl




nitmcu
1ST BCD
1
US
IIS
us
VIM EH
OF C1SSS


a) 8
b) *
Cl 10
3
MieS
) 2.4-12 sg/g |Mt vt)
| ».5-1» qg/g fvejt vt)
I 1.7-6.5 ag/g (vet vt)
I 2.3-7.2 99/9 (Mt lit)
a) lot given
b) lot git««
e) 2.42-4. 19 ag/g vet it
a) lot given
•) lot giT«
a) 2.1 3-4. 6C ug/g
b) 3.26-4.09 ag/g
c) 2.55-4. 20 «g/g
let it
a) lot given
b) lot gi*»
c) lot given
d) lot given
•) lot Jinn
f) lot given
mi i GIIIMI iiroiuTioi
I
i
) 6.0 » or - 4.1 I a) Bales, cexebtan. 1 subjects
g/g (vet vt) | 1) Peaales, cerebraa, 2 sabjects
) 9.3 * or - 6.7 | c) Bales, cetebellaa. 7 subjects
g/g (wet vt) 1 o) Peaales. cerobellaa. 5 sebjects
) 4.3 * or - 1.S |
og/g (vet vt) 1 ftoa a groep of «1 aitopsiea,
) 5.5 » or - 2.0 | forensic aealeal exaaliatioc*. Japan.
g/g (vet vt) I gales. Man age »0.6 re. Teules.
1 ««a» age 37.* yr.
1
1 II1CI niaillS; aOTOPSXBS; JlPlI;
1 unniioa; Hsmc; CIDBIOB; COBUT;
I cnonni: CCIPII: nci; HICOBI;
I iitioa: HiGiisina; iiiGaiisi:
i stsiDius-, unaoiT; SCMDIDI;
1 Eiiniai; Tiiiiioi: wiiDini; znc:
1 GCIC: BBOBJII: titiB: KIDHIS;
I cntBtni; cHiBEima; BUST; ansciis;
1 I licit IS; spmi; iotas; loill:
| IRUS; COHPU1TITE ITILUITIOJS; SIX;
| ICI1ISIC SIDICIIB
1
1
a) 4.11 ug/g 1 a) Vorke>r - oarebrva (temporal)
b) «.2S 09/4 1 b) locket - eerebrua (occipital)
c) lot gi*en 1 e) S coatrcli - cer«brt» (frontal)
d) S.03 ag/g I a) lortor - cerebellui
e) 3.58 ag/g 1 c) Coatrol - cerebellii
let vt |
1 Jafanem voEtor. 65 ji old. at
1 caroaate Erodociog plant for 30 yr.
I tiad of aazlllary aafl lang caacer.
I Ccatrola, £9-78 rr old.
I OKU; iBiposi TISSOI: toaii: BOIK
I guioi; EJiii; cnEBnim; CZEIEBOH:
1 JICIETS; HTn; mss; ausciIS;
| CllCIltS; Sill; CBBOnOI; CCfPEB;
I BRILS; IIIC; IIDISTBIal PlaRS;
| 11B>I»ICI: CCCDPUIOIIL BIZUDS;
| tOttnaHOI IIMSOBB
1
a) 3.23 ag/g I •) City reiideats. lover flacrs
b) 3. SI ag/g 1 E) City residents, apper floors
c) 3.50 ag/g 1 c) Sabarbs and Tillage residents
let vt I l«s«tli« correlatioa (P < 0.05)
Hedians I cttveea orgaaic Pb aad ca.
1 litopslea. Resideats of Copenhagen,
1 Its suburbs, and of Tillages on
1 Haland. ages 12-S« yr.
1
I CtlHHK; 10D1TS; IOTOPSIBS; CBI1DBH
1 imii IXB PCHOTIOI;
1 cicaccnioiinoi: nan IBEIS: L»D
1 CISIIIC CO»C0IDS
1
a) S25.8 * or - 3«.8 I a) Slobns pallidvs. 11 sanples,
niol/g | cceffieleit ef Taciation (CT) 21. 91!
b) 659. 1 * or - 2».» I b) Caadate noclens, 11 sasples. CT
mol/g I 12.3*
c) 7>2.< « or - 17.6 | c) Pntaaen, 12 staples, CT 7.9Y
naol/g j d) Sabstaatia nigra, C sanples, CT
d) 1139.8 » or - 66.3 | 11.2V
aaol/g | e) Cerebral cortex, 19 sanples, CT
e) «95.4 * or - 22.8 I iO.1t
aaol/g I f) lippoeaapas, 13 staples, CT 19.21
f) »25.1 » or - 22.7 I
naol/g I Ktopsy saitlas
Dry vt I
SB | CHZBIal CCBTEX; REISOBSHXIT HBTBDDS
I ciiciiH; copcBB: noi: meinsi:
1 i»n: mopsxis
UfSIZICB
akava, 8.
oiokl-Tasnaoto, B.
naao, K.
Terai. 8.
980
rcniTes of
•Tironneatal Bealtn
S(1):36-««
flyodo, K.
S«aki, S.
Paroya, 1.
•esbizuka. K.
1980
Intematioaal IccaiTes
of Occapational aad
Enviroaneatal Health
»6:1»1-1SO
lielsen. 1.
Jensen, K.I.
Grandjean. P.
1971
latare
273(5671) :602-603
Goldberg, 9.3.
lllen. I.
1981
Clinical Cheaistn
27 (»): 562-56*
                                                                                                                                                                                              vo
                                                                                        (IBXT

-------
Ccfptr
C«
lt> 63. 5«6, tt 10*3 C. BP 259S C, tP  1 •• Hg at  1«2B C,  10 aa Eg at 1870 C
























flSSfff



3*20
tnatk











3821
Bafr




1
1 1
1
1
1
1
1
3S22
Stir
1

1
1
r
i i
i
i



3823
flair
1
1
1 l
< 1
1 1
1 1
1 1
l l
t











M2»
Halt



















ZTfiOSORZ 8O9TZ UllTClClli lOBBtt BalGI
HRBQD OP CaSBS


laaalatlaa PIZE 1 lot linn






1





a] 8
b) 10





I

1

1
1
1 US a) 31
t »| 22







a) lot giro
b) lot gi»«n










mi i CFKUL nroiBuioi i sznnicz
i i
i i
i i
3.8 ag f t I *aapl«d at rat* of 1 I/air, 2-10 I Mtnlnoi, E.E.
I vie aftec batalbg 4 ace v*14lB9 C9d*. \ D«aa«d«l*«Cv G.&«
1 I Joaaaaaon* T.S.
I rilvaralty pljalBB a bop, Florida I Uaeaaater, J-»-
1 1 "7S
1 IIOJIDI; units; B8X1H; CilClOB: | Inaala of occupational
I cnoiIlB; CIBOKOS; COPPZ1; ItOI; | Byglan* 1»:22S-23»
I mi: Baieiiisz: ncm; POCISSIOB; i
l sotroa, iirniiTB: Tiiirijni; ate-, in i
1 M1IOTJOP; TOBSS; mnsnial 1
| 11BOSPBE11S: tBaCZ ZIEBIIS I
i r
1 t
a| IS. 6 * or - 1.73 | a) Pclla-griai | Kr iebmaachiri .
ag/g 1 t) BealtVr »Uont»ac» 1 x.l.r.H.
b) 8,7 * or - O.S7 | | 19T«
ag/g 1 todaaic pvllaoclaa, 16-60 ji old and I laerlcaa Joacaal of
1 b«altar *al«« oocloccoaoalcallr 1 clinical latrition
1 uteita to rillagciaa. I 27:tO»-111
1 1
1 CCPPfl; BX111S; H1EB11 RZtlBOtlSI; (
1 CISZISBS; HEta; BIOOS SEEDS; BITIZ; t
i sui irszasis; inic icias: BUI: i
1 CCBPMI1IVI (VUDITI} t? fft l tj Cettiali I Parkw, 1.
1 1 1«7T
1 laanlaa fllaiblad utf soraal Jit «ad l scluc*
1 att arad* stadant* 1* Canada. I 1»Bfa313) s20»-2O6
1 1
1 cucin; siGiJsios: wmssioB; i
I SCtlOU: caDBItM; OOBILT; const; |
| 1(0 f; IMC; MISMSSX: ZI«C; |
t i cticiTM} imttrts matt; HETIIS; i
I 1 Bill; CBIUBEl: CaMDl |
1 1 1
1 1 1
1 1 E«»i«». 24 c*pnw*atati» I cbittlwbocoagli, B.
I | F>*^analy9ia tcvatatats arc I 1980
1 I tatolatad. tta fcaalbilltr of a I scl«ce of the Total
1 | 1 tells tic. ao-*ash policy foe oair I MTlrooaoat H:33-73
1 1
1 1
1 1
1 1
f
j
1






















1ST








.












1























8.58-15.09 ng/g








- -
1 aDalyals la cvtllacd and sapportod. |
4 1
I fITIZI: TB1CI B1E1EBTS; Bilk; I
1 icsttiiH: ausgizBcn iRBors: i
i fiins; PROIH»SJ ccipuitm i
1 ITJtmtlOIS; 1IBBTIDS; HIIBCn; I
I JPSZdC; B1BIUB; BEOKK; C1IBIOB; I
j c»icn
-------
ccpper
Co
It* 63.5(6, IP 1083 C, BP 2595 C. TP 1 •« Eg at 1C28 C. 10 II  Bg  at  1870  C
                                                                                      (COITIIUKD)
1I3SDI

3*25
lair














•sane
4a«O
lair

















3827
Bait












BIFOSms 10011


















































nunicu
OTBCD
US


































It













HJBBSS
or CISBS
3















»t ^A
1 Jo
b) 2«
0 37
S) 28
a) 16
f) 19













a) 23
b) 19
c) «2
1) 11
e) 26
f) 10








11IGI

) Rot applicable
) lot applicable
) lot applicable
) lot applicable
) 11-35 ng/g
) 1«-68 04/9
) 11-28 ag/g
) 13-39 ag/g
) 16-27 119/9








0 lot given
c) lot given
d) lot given
e) lot given
f) lot given













a) «-10» ug/g
b) 10-2*5 og/g
c) 1-215 ug/g
d) «-35 ag/g
e) 6-»3 aj/g
f) *-»3 ag/g








mi

) 36 «g/g
) 13 09/9
O 56 ag/g
fl) 22 ag/g
«) 19 * or - 7 ng/g
f) 29 * or - 11 ag/g
g) 21 » or - 6 09/9
h) 25 • oc - 11 ag/g
i) 21 * or - 3 ng/g








ag/g
b) 11.0 * or - 1.8
ag/g
c) 10.2 « ot - 1.7
ag/g
d) 28. 5 t or - 4.7
ng/g
e) 31. S t or - «.«
«g/g
C) 20.8 t or - 7.8
ag/g







a) 22 ug/g
b) 59 ag/g
c) 29 ng/g
*1 7 ag/g
e) 10 ug/g
f) 9 ag/g
Medians







eiiiiiL iirosaaiioi

) 10 ao old patient, o& admission
) 11 >o old patient. OB adBission
) 10 BO old, recovered
) 11 BO old recovered
•) 11 COBtColS
f) K Kvaahicrkot patients, on
adiissioi
g) S I»a»hioi!tot patients, xecoveted
i) 1* gatasau patiartl, 01 adnisaion
.) 9 aaiaaint patients, tvconred
Cepper-deficievt 10- and 11 BO olds.
loraal eciticls, aad negative
ccatrols with Hataaana aad
liaahiottot.
C1SI HISTOSIIS: CBIID5II; DISUSES:
mi; COFPII; mils: zuc

b) Tall-ten Ion blrtkveigkt, at
blrtt
c) Pce-tera, at birth
d) Controls, 3 BO
e) Fnll-tera lo« birtaveigbt, 3 BO
f) fre-tert, 3 BO
g«diaas « 01 - si

leoaates in Halifax. Pre-tera gxoap
lean bicthieigkt 1880 g, 26-36 t\
geatatloa, foil-ten lov birth«
-------
CCppar
7M 0-50-1
Cl
Itl C3.SW, I* 1083 C, BP 259S  C,  TP 1 aa Eg »t 1628 C. 10 »  Bg at  1879 C
                                                                                       fCOITIIllCD)



























IISSDS


38 28
Bait















iiMsnts tons






















IIIIRXCIX
RCTBOD
























•3*ea
OF CIS!
























1
1 3B2» I rng«cion us i ai is
I late t 1 b) 17
l| C) 19
It 1 « 15
( 1 i
1 1 1
1 1 1
1
I


1
1 1
1 1
1 1 1

.1 1
1 .........
1
3139 U a) *
(«rt


1
( I
1 I
t






























«>) 2


















IIICB mi i SEiim iiroBRirio*

i
1 1 rc*i« of rarld lltaratar* os tie
I accaavlatioa and bloe>ac*atratioa of
1 acleetad toxic tcac* aatalx la bnaaii
1 atic *>it nil* aad oth«r aaanllaa
1 tali, foe, aiils, clara aed tools.
1 Tatalat«d JIT geographic area.
1 1 «i61«ct», MX. to*. *xpo*ar«.
I | ozadiaat, aaalra** IB ppav and
I 1 attaorltr tret orcr »»0 raf«r«so««.
1 1
I | micii IDSIUtUj C1UD1; CIIT1U
I i «§i»ict: IOBCPB: u»nz nsi; in
I i iiuiu: SOOIB unict; somnin i











1 Vot flTCI
1 *>t «1T«>
lot gl»«
lot jt»««















*| < or « 4.3 «?/9 (nt
•t)
b) 2.<-6.9 «9/J (wt >t)

















I 1511; OIIIJI KII600I; DRTIO STUBS: t
1 aui; iiii5: BifiEt: imioii: i
1 1BSHIC: BOBC»; C1B5IUB; CH08IJB: 1
1 CCI11T; COPPlt: 1111; BISCUIT: |
1 11CIF1; SB1E1IHB; til; Tllllloa; III I
1 icimioi: itiHu paraiinois; t
1 iioiccaamiioi; BIOIIDICIIOIS; HID i
1 foiiBnoi; pcromioi CTPOSOIB; »*T«B i
1 (cuonoi: tuct nimis; anus i
J i
l i
vi/q I t) ••>. klgk blocd (t*<»t« I
b! 10. a t 01 - «o/o | e) IOMI, Ion blooj pr«ssut« |
c| ID. t + or - 3.0 | o) IOHI, klgi blood preside* j
M/7 | £otj«cts Mlacted by blood pnaxur* I
4) 14.8 • or - 2.3 I tait fro> a tnvloM atodf . I
•9/9 1 I*tlaat«d dallr iitaln, 1.5 ag. I
1 I
j felTiaslan tasldamta of To»«lao I
j Iclaida, eroidad eoidltlona, I
I Mtslstoac* «CODO«T. B»n, vaai aq« |
1 «5 tr, aaan bt 167 ca. Man «t T* kg. |
1 Icaca, Man ag« »6 ir, *«ai at 16S I
I em, a<» at 79 kg. I
1 1
I ccppia: sue: BIOOO SEBOS; HIIB: i
l mis; »i»: IM ZBUIID (
i i

BZFBBZBCI


Jeakias, B.I.
1979
BPl-«00/»-79-M9, IBt
pp.




















BcRaazla, J«R.
Gitkria, B.I.
Ftiox, 1. 1. 8.
1S78
laerican Journal of
cHaical latrltloi
31:«J2-«28












a) 2. » » or - 1.8 I a) Balas I Tokav*. a.
»9/J («*t »t) t| reaalM f E
J» «. 8 • or - 3.9 t 1
azafci-Iasaaoto. a.
aamo. K.
ng/g (»et »t) Proa a gco«i of 61 avtopclas, 1 Taral. R.
fonasic aadieal vxaalaatlou, Japaa. 1 1984
Bal«s, a*at age *«.« yt. r«aal«s, f 1
ccnlTei of
a*a> a«a 37.1 rr. I EmrironMiital Baaltt
1 3!
1I1CI 1LIBIITS; HTTOPS1ES: Jlfll; t
atORIIil: llSniC; CIDBIII; COB1LI; f
cnoBios: CCCKI; IBOI; aiBctrar; i
IltlM: llGIBIBB; UieilZSB; |
iOtlDHI; IITIIOIT; SCHBina; (
stmria; tnuiai; tiiioina: •Jisc; i
GCID; B10BIII; UCTEB; KIDIBTS; I
ciiEBBii: ciimiua; BUST: lasctES; i
CIKBBIS; SPIUI; LUIGS: 10ST1: 1
aitus; coirumn iriivincis; ssi: i
rcmsic Biticiii i
i i
(«tii Pie i)
>
-------
7MO-50-8
Ct
lt» 6J.5«6.
            IP 1083 C.  St 2595 C, TP 1 •• Bg it 1628 C. 10 •• Sg at 1870 C
                                                                                     (COBtlHEV)
HSSIt
3831
Kidney
3832
Kidney
3833
Kiaaey
EIPOSOBI BOVTX



iBixYTicu
RTBOB
u
us
n
•0IB8B
or cisss
) «
) 2
«) 1
b) 5
a) 8
b) 9
CJ 12
S1BSB
J 1.5-3.8 ag/g (»«t wt)
) 1.«-3.0 og/g I 1.07-1.19 ag/g
b) 0.89-3.72 «g/g
C) 0.82-3.58 ag/g
Bet «
iui | eiiiiti. iirosufioi I MPIBBBCB
i i 	
1 1
a) 2.5 » or - 1.1 1 a) Bales I Takana, S.
ng/g (»«t »t) 1 t) resales 1 Sazati-lasnaoto, a.
b) 2.2 + or - 1.1 1 1 »»aao. «•
ag/g (»et rt) 1 Hoi a groap of 61 utopsies. 1 T«rai. B.
I forensic ndieal ezaaliatioas, Japan. I 1910
I Bales, Ma» ao* ao.6 yr. P«aal«s, 1 IrchlTM of
1 a«a« am 37.* jr. \ Intitouutal Malth
I 1 35(1):3«-«*
1 nici niBiiis: lOTOPSixs; juai: i
i iiciimB: iisnic: CIBHOH; COBU.T: i
| CIBOBTDl; COFPBB; IIOI; BIBCDBt; 1
1 IltCTB: BKHSXHB; BiIMlISI; 1
I ItHIVira; 1BIXBOBT; sciiDIOl; I
1 siimus: mum; TIKDIDB; sue; i
| CCLD; B10RIBB; 1ITB1; EIDBZ1S; 1
I ctBiBira: cntBitittB: BSiBi; anscLiS; i
I FMCB113: SftESIi LOBGS: ICSTl: 1
1 iittts; coiiniTin BTiLoitiois; SET; i
1 ICBHSIC IICICIII 1
1 1
1 1
a) 1,«9 ng/g »«t vt | a) lork«r 1 Bjodo, K.
b) «ot givei | k> Co«trola 1 Somki. S.
1 I Tncnra, S.
I jaiaHi* «ott«E. «5 TE old. at 1 Beskliaka. K.
I cttoaata (ceaaelag plaat foe 30 TE. 1 19SO
1 tied of •axillary aid long cucnr. 1 International irchlTos
I Ceatrols, 59-78 jr old. 1 of Occapational and
1 | iBTtCOBMatal Baalth
I J»II; IDIPOSt TISSOB; IOBT1; Bon I «6:1«1-150
1 iiBim; BSIIB; CIIBBELLOB; CZBBIIOB; i
1 KIBIITS: 1ITEB; lOIGS; HUSCLIS; |
| I1BCBB1S: SKU: CBBOnOH; CCIfSS; I
| BFtltS; ZIBC; IBOOSnilL PlllTS-. I
1 IIBIUTIOB; CCCBFlflOIU, HIZHDS; 1
I fCPOIlTIOI IIKSDBB 1
1 • 	
	 1 1
a) 1.57 «g/g | a) coatcoli 1 Brrae, B.
b) t.6« «g/g | t) Iock«r gteap I 1 BoEdbeEg, C.
ol 1.66 ng/g | c) «ork«r qcoip It 1 s«st«r, P.O.
let it 1 1 1'80
Rediaas I C«c«as«4 rofisorr and Melt.r 1 Science of the Total
| •cikacs. ag«> 55-76 TE. exposed to 1 InTitoaaent 16:13-35
I k«a*T tetali 1-3 decades. Tiaa 1
1 tctveea Eetlteaeat and deata 0-1. S yr 1
1 la groip t aad 2-19 TE. groap II> 1
| ccattola, agas »3-72 yr, »»o ll»ed 50 1
j ka fro a the factory. Svedea. 1
I jiiDii: ciBaTEBS: mo«TS: LITIB; I
I miss: coMitmn iTiiniTiois; I
1 lltBSTBIll BTGIBIB; BIISUIIBIBT 1
1 (HMDS; 1RHOBT: 1BS1SIC: C1BHOB: I
I CISlnfl: CBICRIDH; COB11T; COJPEB; I
i «c»: HOB: itKBMW: LEID; |
t BIICIIISI; BZBCOBT: BOLTBDHOR; 1
1 IBCSPHOSOS; BDBIDIOB; SC1BDIDB; 1
| SZ1ZII1M: SJ1TCT; TI»: THIGSTJB; |
1 IIIC: BBIItB H121SBS; IIODSTBIll 1
| tllBTS; SBtHEBS; miBBIUH |
1 	 1 	
                                                                                             net)

-------
ccpper
74.40-SC-8
Co
»« 63.546, IIP 1083 C,
                       BP  259S C,  TP 1 •• Hg at 1628 C, 10 ••  fg  at  1870 C
                                                                                       (CORIRBED)
1
1
1
1
1
1
1
1ISSO! BIPOSIJBZ tODlS ASAIYTICA1 B0BBZB
HETHOD Of C1SI.
383* U a) 10
liver b) 3
1
I
1
1
1
1
1
3835 1 US
line \
1
1
1
1 1
1
1
1
1
1
1
1 1
1 I
3836
line
i
1
1
3837
lifer
I
»
»
f
1
1
Ingestion
»
1
1 M
1
4
«
«> 1
1 b) 5
1
a) 8
b) 9
c) 11

I1IGX
>
a) 3.9-38 09/9 <«»t vt)
b) 3.0-8.2 ag/g (net vt)
a) lot given
b) 1.16-10.20 ug/g vet vt
1
1
a) 1.44-6.9C og/g 1
b) 1.30-5.2* ag/g
c) 1.38-5.52 og/g
let vt

BXAI | GZIIB1L IlfOHBlTIOl | BSFS8ERCZ
1 1
1 1
1 1
a) 16 » or - 12 og/g I » Hales I mkava. 9.
(vet vt) | I) Females | Snznki-Iasnioto, B.
b) 5. 9 » or - 2.« 1 1 Amano, K.
ng/g (vet vt} 1 From a gromp of 61 autopsies, I Terai, B.
I forensic lexical examinations, Japan. I 1980
j Bales, lean age 40.6 jr. Feaales, I Archives of
I lean age 37.4 vr. I Environmental Health
1 1 35(1):3«-44
| TBACE BLIMBITS; AUTOPSIES; JJPA5; |
| AIOsImTJg; ABSEIIC; C1DHIOH: CO BUT; |
| CBROHIUS; COEPBB; IBO»; HBBCORI; |
1 UDmn: aiciEsioB; uxsarxsz; i
I IOEIEIII1I; 1III8OIT: SCAHDIUS; |
1 siLEiins: iiiMios; Tinoioi: ziitc: i
I SCH: BSOBIIE; LITEB; KID1XI5; |
t ClSnimi; CHEBE11UB: BK1BI; IDSCLES; 1
| FIBCBB1S; SFIEXI; tDIGS; 1CBIJ; |
| BIT1LS; COHFUITITZ BTltUiTJOKS; SET; I
| FGBEISIC SICICIHE I
1 1
a) 4.26 ng/g vet vt 1 <) worker 1 Sjoia. f.
b) lot given 1 t) Controls I Suzuki, S.
I I FuruTa, H.
| Japanese vorkec, 65 Tr old, at I Heshliola, K.
I cntoeattt Fccdocing plant for 30 yr. I 1980
1 Cied of •axillary and long cancer. I International Archives
I Ccatrols, S9-7A yr old. I of Occupational and
I 1 EnTlronieatal Health
| JAEAI; ADIPOSE TISSUE: AOBTA: BORE I 46:141-150
I B1BBOB; EBAII; CEBEBELLBB: CEBIEBOI; 1
I KICIIIS; IITfS; LUBGS; BOSCIES; |
I fllCBEAS; SKIS; CBEOBlaH; COIPEB: I
| BETAISJ ZIIC; IBOHSTBIU PIABTS; |
I I1BAIATIOB; CCCBPSTIOKJ1 B1Z18DS; I
I ECPOIiTICli UPOSOBB I
1 1
1 1
a) 3.59 ag/g 1 a) Control! 1 Brune. D.
b) 2.91 ug/g I t) socket gtcap I 1 Koraberg, C.
c) 3.08 ag/g 1 c) socket group II j tester, F.O.
Ret vt 1 I 1980
Medians | Ceceased refinery and saelter I Science of the Total
1 vcrkers, aqes 55-76 TT, exposed to j Environment 16:13-35
1 betvaen retirement and death 0-1. 5 rr 1
I in group I and 2-19 rr, group II. 1
1 Centrals, ages 43-72 re, vbo lived 50 1
1 ki ftoi the factory. Sveden. 1
1 1
1 SfECZB; C1DATZRS: KIDIET5; IIT5B; I
| I DIGS; COBPIBATIVB BTA1UATIOIS; |
I IIEOST8IAL BTSIEIB; HXASOXEaEMT I
I BITBODS; ARIIOII; 1BS1IIC; CADBIUB: 1
I CISIOR; C BBC BIBB; COBALT: COPP1B; |
| eCID; 1501; IllTHAHOS; LEAD; |
1 eiiGiiist; incvBT; ROXTBDZIDI: I
1 fBCSPHOBDS; BDBIDI01: SCASDIOH: I
I fHEIin.l; SIITE8; TIM; TDIGSTH: I
1 !UC: gtllTB BAZABDS: IIDOSTBI1I I
1 tl«RS; SBtllSBS; TEL10BIV1 I
1 1
1 1
1 tevlev. Profile of healthy snb-Jects. t Gnthrie, B.E.
I Baseline data for determining changes I Bobinson, B.F.
1 in intritional status froi indnstrlal I 1978
1 feed processing techniques. i Rev Zealand Sedleal
1 I Journal 87(6031:3-8
1 111 ZtrLAIt; ADULTS; FITOS; HF1I7S; I
1 I1CCD SnV
-------
 Ccgtn
 7«««-5»-»
Co
JMT 63.5*6, If 1083 C, BP 2595 C. TP 1 M Bg at 1628 C, 10 •• »g at 1870 C
                                                                                     fCOITIXDED)
nssvt



3838
long


















3839
lung

















38*0
tinq






















tXMSDII SOME


































































IIU.TTICU
8ETBOD


U



















US


















U























IDSBEB
OF CaSKS


1 2
b) 2





































a) 8
M 9
c| 11





















11*61



J < or » 5.2 «g/g (»et
t)
1 0.9-6.2 og/g (net it)

















a) Bot aiTen
bj 0.77-1.59 agyg
c| Bot giteo
A) 0.60-1.32 0.9/9
a) lot giTst
f) 0.81-1.96 aoye-
Bet it












a) 0.62-1.M ng/q
b) 0.17-1.5* «g/o;
c) 0.059-2.15 ug/g
It «




















BUB | ClBIBal IBYOBBaZICB
1
1
I
a) 2.6 * or - l.< 1 a| Balea
g/g (vet vtj I t) Feaalca
b| 3.5 » 01 - 3.6 |
ng/g (vet »t) 1 'roa a group of it autopsies.
1 fortnslc ndical exailBatioas. Japan.
j Bales, Mai age «0.6 rr. Maales.
1 ie»» aae 37.* yr-
1
| IB 1C I CISBTBTSS iOTOPSIES; JiPlt;
| limiTln; IES1IIC; CIBBIOB; COB1LT;
| CEBCIIDB; COPPIB: 11013 HEBCOBTj
I utiua; SMIESIDB: BIBSIBBSS:
I iBiiDivi; IRUOII; sctmn:
I sui«n»; TinBita; niioina; zinc:
| GC10: B10RIBI; LITER: KID1ETS;
i ClSIBfiajj CltEBBttOB; HE1ET; BOSCIES;
i EiBCBEis; spiiEi; imns; icrti:
| BITtLS; COBPU4TITE EYUOITIOBS; SEI;
| ICBE1SIC BIEICIBI
i
a) 0. 5S ng/g I a) Sorter, right upper lobe
b) Hot gi»e | b) 5 eoatrols. tlqht upper lobe
e| 0.96 uq/g j el Borkar, right loner lobe
4) lot qiven I 9) 5 coattol*. right lover lobe
e) 1.02 og/g I «l Borker. left upper lobe
f) Bat give* I f) 5 contrail, left upper lobe
let vt |
1 Jtpaiese "or*«r, 65 re old, at
1 chroaate ftodaciim plait toe 3O 71.
I Clad of aaxillarr &*& laaq cancer.
I Ctstiols, 59-18 TT oia.
I Jicii: IOIFOSE f ISSUE; aoBii: son
| SIISOW; EBIIli CUEBZL10B; ClBEtSdd;
I Hums: HTiB; LDUSS; nosciES;
| ElBCBtIS: SHI: CBBOBIOT; COPPEB;
| R1T1I.S: ZIIC: UDDSIBIIL PlIBTS;
\ imilTIOB; OCCieKKniL UtlSDS;
| ICfOIftTTOB ZXPOSOBS
1
a) 1.10 ag/g 1 a) coatrclc
b| 1.0* ng/g I t| torkec grenp I
c) 1.0* og/g | c) Borker group II
Bet vt 1
ledians I I«c«asad cef luerr and aaelter
1 vorkera, agea 55-7$ jt, expose! to
1 aaa*r aetala 1-3 decades, tile
I bcteeea cetlieaent anl death 0-1.5 rr
| in group I aid 2-19 Tt, group II.
j Controls, aa«a 13-72 ji, *io live! 50
I ka froa the tactorr. Sveden-
1
| JKtEB; C»D»TEES; KIDIITS; IITiBj
| IOISS; COBP1FITITE ETILD1TIOJS;
| IBDOSTSItl BTOIBBB; BEaSaiEBEBT
| SITBODSj inilOBT: 1SSEBIC; C1DBIOB;
| CISIOB; CKICUOl; COBlllj COl?ZI;
| CO 10; IBOB; I1BTB1BQIT; 1»D;
i iitGiitst; stacnii: sonBriiBB;
| tBCSPROBOS: BDBIOIOR: SCaBDIOH;
| SltBHUS; 5IITEB; Tit; TOBCSTEB;
| tIBC: B!IITB B1I1BDS; IIOOSTSIU
| HUTS; SIIHEBS; lEliaBIOH
1
tEIEBBBCE



Tukava, 5.
Sninki-Ia«naoto, I.
laaao, t.
Teral, B.
1980
archives of
laTlroaMBtal Health
35(1):3C-*«











.._
Byodo, K.
Suzuki, S.
Fttrwa. 1.
Beshlznka; K.
1980
Interaatloaal Irchlres
of Occupational and
EiTlronaental Health
«6:1*1-150









— ™
Braae, D.
Bordberg, 6.
Beater, P.O.
1980
Scieoce of the lota!
EiTlrona«nt 16:13-35


















(BEIT PtGC)

-------
7M8-SO-S
c«
It* 63.S«C. ST  1083 C. BP 2595 C. YP 1 M Sq at 1628 C,  10  •• 89 *t 1870 C
                                                                                       (COITIIIIED)























1
1

1
1
r
i
i
i
i
i
i
i
flSSOE EXPOSDIB BOOTS

38*1 Ingeatloa
Bilk






1
1
1
1
1
38*2 1
Bssele I




1
1
1
1 1
1 1

1
I
1
1
1
1
1 1
I i
1 1
iiiiTTicu.
BETBOD






.






la






IDBBIB
OF USES













a) a
*) e






BIICE














a) < or « 5.2 ag/g (vet
vt)
b) < or • 7.6 va/g (vet
vtj




1

1111 | SfitBll IBTOBBallOB
1
1 Serie.. profile of kealthy subjects
1 BacellM data foe deteeidnlng eaange
j la latrltional states (con lidestrla
1 feed processing teckniqaes.
1
I in itutic: UDLTS; rr«s; IIFMT.S;
| FIOGD SEIffB: BUB; KIDIETS; LITEB;
| lltK; lETIil; DIRS; FOODS; SOILS:
| TIGBT1TIOI; CIO BIDS; COPPEB;
f BlieilESF; IETA15; ZBaCE EIJHIBTS;
| ZIIC
1
1
a) 2.1 * oe - 2.3 I a) Hales
ag/g (vet vt) 1 t) fesalas
b) Z.O * oe - 2,« )
ig/g (vet vt) t (cos a groaF of Ct aatopsles.
| feceasle aadlcal ezaalnatloas, Japan.
1 Bales, neao age *o.t re. resales.
1 sean age 37. » rr.
1
| IBICt ELEiEITS; aVTOPSIES; JaPlI:
1 IICBIIOT; 1BSCTIC; CUBTOB: COBU.I:
I | CBBCBTBBs CCFPBB: I BOB; BB1CDFI;
| | IIDIB1J aiSBISIOB; BaieilZSE;
1 | IBCmotl; 1IIII01T; SC1BDIOB;
1 i seiBBTOS; uiaiTOB: niiDioB: ziic;
1 i i eciD: BIOBIII: IITEI; rums:
1 1 | CMIBSOT; CEflBElLUS; BB*Ht; HOSCIES;
1 1 1 MICJ11S; SPIFBI; tUISS; 10IT1;
I 1 1 BmtS; COBPIB1TITE STILOITIOIS; SH;
4 | | FC3HSIC BICICIII
1 11
f II
1 38«3 | I US 11 lot glreo I 0.50 ng/g vet vt I
1 flu
1
1
1
1
1
1







38««
lall




















sole | |
1 1
1 1
1 1
1 1































1
1



































II 1 1
|J | | Japanese vorker. 65 rr old, at
II 1 1 ckroaate pcooiclag plait far 30 re.
|| | I tied cf saxlllarj asd lung caacer.
II 1 1
1 1








1


























































I J1FJB: 1PIPOSE TISSUE: 10BTI: BOIE
| B1BIOI; (Sail; CIBEBniVB; CEEBBSOBi
I SIOBETS; tITEB: IOIS5; BQSCIIS;
I E1ICIII5; Slllt CB80BTOB; COFPIB;
| BrillS; ZIIC; XIBISTBIal PI11TS;
| 1IBII1TIOI; CCCnPlTIOIal BaZUDS;
i toremioi IIPOSDBE
1
1
1 1 revlev at vorld literatare ox the
f accoselatton and bloeeoeeatratloa of
1 selected tezlc trace eetals la kaaan
1 late aai aails and other aaaaali&a
1 halt, fie. Balls, elavs and hoofs.
1 Iitulated by geographic area«
t gcadleat. aaalrses In pps, and
1 aitborlly feea ever 100 references.
1
| Illicit 10STBU.II; C1I1D1; CF.ITNL
| lEllICI; IOt«E; BICCll BIST: in
I miiio: soon uraici; SOOTKEIST
| ISII; OiniD KHSDOB; U»ITtD STITES;
| Bill; IU1S; 1EVI3B; 1RIMIT:
I nsiiic; BOici; ctDBm: cBtcHin«:
\ CCS 111-, CCKll.; UkD; 5SBC11ST;
I iiCKEi: sninoB: TI«: IIBIDIOH; in
I CCUOIIOI; Itlaftl ffOPQLatlOIS;
I lUiccuniKioi; iioiiBiciiiou; LUD
1 icturrioB-. PCPVLITIO* ETPOSOBE-. IITSC
i tciintoB: TIUCI simns; BEXILS
i
•IFESEICE

Gotkrle. B.E.
Sobiason, B.F.
1»7*
lev Zealand Helical
Journal 87(6031:3-8








Tokava. a.
Snzaxi-Tacniaoto, !l.
iaano, n.
Teral, B.
1980
lechlres of
Fnrironnantal Be alt b
35(1):36-4»













eroto, E. |
saitttl, s. |
Fnrora, 1. |
aesaizaka, 1C.
1980
International Irchires
of Occopatlooal and
IDTlconnental Health
4(:iai'-iso






Jenklas, O.I.
1979
BPl-600/»-79-0«9, 18«
PP.




















































                                                                                                                                                                                             o
                                                                                                                                                                                             NJ

-------
Ccpp«r
7MO-SO-«
Co
Itt 63.5««. (F 1013 C, W 2595 C, TV  I u B* at 162« C, 10 (a  B?  «t  MTO C
                                                                                         (COVT1TID*9D)
nssn

38«
lall













3*a«
Faacreaa

















3817
Fa«ct«a*













3048
Faaryax














IPOSBBJ toBiz

atLoa
































































1H1TTIC1I
BETIOV
US














u


















us






























mm
OF C1SXS
> 15
17
19
1 «











a) 5
M 2

















a) 1
b) 5













a) 1















I1KE

) lot jlY«n
I lot 9iT««
1 lot give*
1 lot giT«n











a) 1.4-1.9 ng/g (wet wt|
*) < or « 2.0 ag/g (wet
•tj
















a) lot gl»«»
b! 0.46-2.2? ag/g ««t «t













a) lot glT«a
t) 0.90-1. 16 «g/g ««t at













Bill

1 15.6 t or - 1.8
g/g
) 21.9 » at - 27.9
0/9
O 23. » * oi - 12.9
<»/g
1 10.4 * oc - 0.5
9/9







a) 1.7 * or - 0.2
09/9 C«t »t)
b) 1.0 » or - 1-»
B9/9 <"«t wt)















i) 0.39 ag/g not wt
b) lot glvea













a) 0.80 ag/g not wt
b) lot gin*













t
CM mi moisiTioi

t) lei, low 11004 prastare
b) Bea. high bloct pxesrare
c) loan, low blooi pressace
{) loata, high blood praasare
S«b1«eta Ml«ct«a bT blood prasaura
tank fcoa a trarioa* st«di-
fatlaated daily latako. 1.5 19.
FolrMSlaa culftaats of Tokclaa
Iflaidi, erotted condltiona.
ntalstamcc aconoar- Son, Ma* «g«
4! it, aaai It 1*7 ci, Man »t 7» kg.
Bcna, Mai ago tS rr, aoan It 1«S
ea, aaaa «t n kg.
tepPH; me; Bioon SSBOB; BUI;
nils: quit; in nuui
a) Bates
1) F«al«s

ftoi a groat of «1 aatoo(l«s.
forniic acOlcal ozailaatloa*, Japaa.
B*l«a, Man ag« »0. 6 jr. r«aal«a.
a«aa ago 37.4 jr.

met ziMcns; inopsits: j»pn:
itoiiigi; aisEBic; ciDBina: COBU.T:
cnciini: cctPiB; IMIJ SEBCHBI:
tlCtOC BieiKlOB; UI6UMS:
BttlDiuri; iiiinoir; SCIIDIDB:
stiTiivi; iiiuiint: miDioB: znc;
eclt; BSOBTIl; tniB; IIDIIIS;
Clllim: CIBEBE1LOBJ BEIBT; RDSCIBS:
IllCtllSt SIIEII; tllSS; 10BTI;
BtTUS; COIIaUTITB STliOllIOIS: S!I;
FCBIISIC BEIJCIBE
al lorkar
b) Coatrols

japana* worker. 65 rr old, at
chxosat* fiooaclaa plant for 30 TC*
rial of aaxillarr aa4 lang cuear.
ccatrot*. 59-78 rr oW.

Jim: IOIPOSE nssuEi toiti: sou
mm; Hiii: cmaniw; cnsspon;
(Ifiins; llttK; LOISS; MSCUS;
fiicms; ssii; cstoaoH; COEPSH;
cmiSi tile; inastiiu HMT$;
iiitutioi; cccnusnii «i»»s;
cctaimci ZIFOSOBB
a) lorkar
b) Coatrola

Jacaaew werkar, 85 rr oil, at
caxoaate prolaelng plant tat 30 TC.
Cl<9 of aailllUT and lung ca«c«r.
Ceitrols. 5S-TS rr old.

J1FII: 1DIPOSB TTSSOIJ 1OBT1; BCIE
Mtioi: BBIIB; CIBEBIILOIIJ CIBEBRUB:
IIDIHS; UTEB; IOIS5; BOSCltS;
UaCEfIS; SIM; CBROnuH: CCEPH;
HIIIS; IIIC; IIDOSnilt FI1ITS!
llltUTIOl; CCCOPIIIOHII. B1Z1BDS;
fOfDIITIOl IIFOSVIB

BHEJMCI

ncKoaiie, J.a.
eothrlo, B.I.
ftiot, I.l.S.
197*
lavrican Joans 1 of
Cllalcal IntrltioB
31:422-428








Tnkawa, S.
Sankl-Taoacoto. B.
aaaao, x.
Taul, I.
1980
archives of
Eftvlxorattatal Health
35(1>:3«-44











ITOjO, K.
Sazakl, S.
TttTUJB.* !•
Beshixvka. S.
1980
International archive*
of Oceapatlooal aad
EavlroBmaatal Health
*«t1«1-150






Hroio i
Suzuki, S.
I«r«ra, I.
Reshixuka, C.
1980
iBtenatloaal IrehiTes
of Oceapational a&d
r«Tlrota«atal Health
46:141-150







(IIIT FISB) 	

-------
ccpper
7440-SO-8
CD
lt» 63.546. IP  1083  C,  B* 2595 C. TP
                                       1  m» Eg at IC2« C.  10  ••  H<7 at 1870 C
                                                                                         (COfTXItTED)
IISSDE txzosnn Boort AIAITTICAI i amsxt IAIGE i »g»i i GEIIKU HEOBBATIOS



3849
stin










i

1
r

3850 I
Spinal 1

1
[
1

1
1 1
1 1
1 1
1 1
1 1
1 1
1 1
f 1
1 1
J 3851 |
1 Spleen I
1 1
1 1
1
1
1
1



1
|
1







3852
OriM




























IITEOD | OP CASES I (
I If
1 1
IAS a) t a) lot giTen I a) 0.38 ag/s vet vt I a) torlter
b) 5 b) 0.29-0.45 ng/g »et at 1 b) lot given I tt controls
1 1
1 I Japanese aocler, 65 vr old, at
1 1 cbzonate rrcdaciag plant foe 30 yr
1 f 1 Bled cf aazillarr and long cancer.
1 1 Controls. 55-7* yr old.








t

t I-rar opectros 1 a) 7
1 1 VI 12
1 1
|
1
1
1
1


t
1
1
1
1
I
1 1
1 »A 1 a) 5
1 1 W 3
t 1
1 1
1
1
1
1
1
1
1
1
1
1
1
1





Coloriaetrr



























4










1 1
1 | JJf»«: ADIJOSE T1SSOE; AOBTli BOIE
I | MItOf; BR1I1; CBtlSBlIDB; CEIIEXD
1 i mains: iiTEE; trass: mrsciES;
1 1 IIICBEAS; S*M: CBBOBICPS: CCPP'fl;
1 | HTALS; II 1C: IIBOSTSIAl M.AWTS;
1 1 IfBltATIOl; OCCUPATIO9AI HAI1BOS;
i i icpoimo tnosniE
1 1
1 1
a) 35.3-182.9 ag/g; I a> 89.0 * or - 57.6 I a! flotor teuton disease patients
b) 19;7-11S;i «g/g I ag/g I t) Controls
Brr «t I b) 06. J + or - 23.8 I lentral horn ttssm, antopsv
1 ng/9 |
1 B*T »t 1 latients tlef of svotropnic lateral
1 1 sclerosis and progressive nvsculae
1 1 atrophy, Kan a««. Si. 6 » or - 13.1
1 1 it. Controls died at various
1 1 diseases at <0.9 » or - 11.1 jr.
t 1
t l itEis: »onis; Anopsus:
i i •lOBoaoscniii DISEASES; SPIVAI ODII,-
1 1 tlOACCWglATIOI; CllCIOS; CCtPBB:
1 { IfCI; IHC; BtSEAXESZ; BIHlSj
l i smnoR; ZIK
f 1
1 1
< or » S.t ag/g (*et I a) 2.2 + or - 2.1 I a| (ales
t) | «g/g (wet vt) | 1) feaales
< or > 3.8 ag/g [vet I b) 1.3 « or - 2.2 I
) 1 ag/g («et "tl I Hot a groap of Cl autopsies.
1 1 forensic sedieal ezaiinatioo*. Japan.
1 1 Bales, nean age «0.« Tr. Fewtles,
1 1 s«aa age 37.4 fr.
1 1
1 1 IIACE EtERmS; AOT07SIES; JAPAI;
1 1 AZ8BXIOI; IBSIItC; CtDBIOB; COB1LT;
1 i CEDOEta*: CCPPEB: IBOS.- UJBCBBT;
1 i mm: IAGIISI«C lAifiAEisx;
1 1 PUSIDIDS; AHIROBT; SCAIDI08;
l i ftiEiivR: inaiura; VAIASIM; znc:
( l ecu; BRomi; tiTEl: Hours:
l i ctBZBtm: cttEBEimi: BEA»: ROSCIES;
1 | FIICBIIS; SPICTI; LVKS; 10B1A;
1 1 IIETA1S; CO(IP«BATI»S CTAU7ATIOS: S!I:
1 | rCMISlC HECICIIE
1 1
1 1
>} 22.8-7&.J ag/24 ar 1 a) 52.4 «g/2* fee 1 a) Initial levels
i) 38.6-130.6 ag/2* kr I b) 89.7 ag/24 ar 1 t) Dorina 5 f leecine aallv
:) 35.4-103.2 ag/24 hr t c! ''2.1 «s/2« hr 1 el S iars after leaclne vithSraral
1 1
t 1 B«altkr volnnteers.
1 1
1 1 CCIIEI: 1ETALS; limit 1E1AWI.ISH;
l l tistASfS; mil: BICOD SIIOB; oint;
1 1 SK» CISEAStS; ABIIO ICIDS; Ball;
1 1 CCSPAIITITI tfAlOATIOIS
1 1
(MET PIG I)
I BERBEICE
1
1
I
I Bvodo, E.
1 SanU. 5.
1 Tarara, E.
1 Beshizoka, K.
| 1980
1 International Archives
1 of occupational and
1 Envlrannental Bealtb

': 1
i
i

i
i

i
1 Knrlaader, 1.8.
1 ratten. B.I.
1 1979
1 Annals of Veorologv

1
1
I
1
1

1
1
1
1
1
1
1 Tnknva, 8.
1 Sazaxl-Tasnsoto, 9.
1 Asano, It.
t Terai, I.
I 19BO
1 Archives of
1 Environsental fiealti
1 35 J1): 36-44
1

1

I
1

1

1
1
1
I
1 Kriabnaaachari,
1 K.A.V.B.
1 197*
1 Aserlcaa Journal of
t Clinical Intrition
1 27:108-111
1
1
1
1
I


-------
7«»0-50-8
Itf 63.5*6, HP 1083 C. EP 25-95 C, TP  1 « Eg at  1«28 C,  10 as Bg at 1870 C
                                                                                      (CO«TI*0!D)
TISSUE
3* S3
Orine














ETPOSORE BOTCE
lageStiOn















1MLTTIC1I
MtBOt
US















1 OH BIB
OF C1SSS
al IS
bl 17
C| 19
3} 15












B1IGS
a) lot given
b) lot given
C) lot given
d) lot given












nil
a) «3 + or - 51 ug/2»
to
b) 3« « or - 22 ng/24
ht
c) 31 * or - 29 og/2*
hr
4] 25 * or - 8 ag/2«
hr








CII1B1L IITOB«4TICI
al Be«, Ion tlood pressure
t) gen, high bloed pressure
ct Boiaa, law blood pressure
dl voiav, high blood pressure
Slblects selected by blood pressure
rank froi a prerioas stady.
istiiatea dallT iitake. 1.5 ag.

EolTneslai ccsLdanta of Tokelav
Islands! croioed coDditioae,
Eitsist«ce econo»T. Ren, seal age
»i TC. aaa« ht 167 cm, aean «t 7» kg.
«o««n, icaa age *< yr, aeaa tt 16S
c«, *eaa tt 79 kg.
CCfPEB; 11K-. BLOOD SEBBB; B1IH;
I1ILS; mill; III liiLin
EIJEBEICE
BcKenzie> J. a.
Guthrie, B.E.
Prior. I.I. I.
1978
aaeclcan Journal o£
clinical latritioa
31:«22-*2»









 Ccvaarla  (9  CD
                          CI)
 *1-««-5
 C4-B«-02
 » 1*6.1, HE 70 C. B? 291.0 C, It 1 na 89 at 106.0 C
iissat
3««
Breatl












zitosors sornt














itUTUCU.
8ETHCD
8C-BS













lOBBIE
OF CISIS
?a (387
sanples)












EilCE
lot given













asii
1.0 ag/1
Geoaetric












etltitl tllOBHlTlQl
teacacei at 25 C and 760 nn Bg
63.1^ occurrence
Ic>er aad upper ooe-Sigaa Units 0.2«
aad ».2 iq/1

KalthT, U-35 TC old, nonsaelciiig.
or tan blacks and Caucasians.
Cnlcago, II. tlgidlT-contcolled
ciperiaeatal coidltions.
HI1TI; tICCBOLS: IltllOIS; IDBLT5;
CEtOBKlTIO ETOBOCMBOIS; TOIiTILE
cieinc cosEcmtDS; BEILTH BIUBDS;
IIR1I1TICI; SETltOLISI; HET1EOLITBS f
FCPClltlOI ETPOSOIE; HBB1I ISSiS
EETIEEICE |
Krotosrynski, B.K.
Sraneaii, 5.H.
C'Heill, H.J.
1*79
Journal of Inalrtlcal
Toilcoloqy 3:225-23*








  Ctesol (8 CI)  (»«»
  Ibenol, aethjl-  (9 CI)
  1319-77-3
  C1-B8-0
  BI 106.10. »P 10.9-35.5 C,  BF  191-203 C,
                                            W  1  an Bg at 38-53 C
TISSUE
3855
DCi DC









HtOSOBE BOOTS
Deraal










ItllllTICtL
flETHOD
9C










• OHBI9
OF C1S3S
a) 15
b) 10









B1IGE
a) 8.8-128.5 ag/g
creatisiDe
b) 31.7-**. 8 ng/g
creatiniae







9Z»
.
a) lot given
b) lot given









cziiau. iiFoaauici
a) Controls
t) (orkecs eiposad to chlocaphenols

forkera in barbicide nanaf actariiig
plants.

6I8BICIOES; HOB STB III P11ITS;
CCCSPtTIOIal B1I»EDS: PESTICIDES:
FCEOLtTIOW IiraSOBE: HMSOBEKin
MTIODS; CB1CBIIS OESIIIC COHP00KD3;
FE'IOIS; C»HD»; OBI1Z
EZrZBSICZ
Tan Boosialen, P. 3.
Klein, t.l.
Oranaond, I.
1980
International archives
of occupational and
Environmental Health
*5:57-6Z




-------
    C»«M  (8 CI)
    Eenxene,  (1-nethylethyl)-  (9 CI)
    58-82-8
    c«-Bi2
    •I 120.15. » -96 C. BP 152  C.  TP  10 »  Hg at  38.3 C
IISSIE



38S«
Breath










3 §57
Breath I
1
1
1
|
|







Eiposms BOOTS















1
1
I












AIA1TTICAL
BETBOD


SC/SS











GC-BS













I ITJSBBS
I OF CASES
1
1
8











54 (387
saiples)












11KI



lot detected-21.0 ng/hr











I lot given
t
1
1










8»l



2.6 ug/hr











0.3 It ng/1
SeoMtclc












eiBiBAi. MFOSBATICI



Ccipond related to norul
xetabolisi. lo other details given.
Cryogenic caipling technique.

Beilthy eilitarr and civilian
eeployees, 0.$. Air Force School of
lerospace fledicine, ages 23-»7 yr. 3
iiokera.
Efizms; CBIOBIUTEC STDBOCIEBOJS;
CflCBIlE CBG1IIC COIPOWOS:
csioBOBHiznis; FiocBin COIPOHIDS:
fttits; ilcceotS: fins; 1DOITS
«ca
-------
CFClotuaM
CC-112
II t«.1S, IF 6.5 C.  8P  SO. 7 C,  W 100  H  Bg at «0.8 C
1155*1

3B59
Bianh












nrlaa







nfOSOBS BOOT!















Bactal







iiumcit
KEf BOD
SC-BS













9C/B5







IBB BBS
or cisxs
5« (3S7
SMplM)




















IltEE

lot 4i**i













"''" "* 1Vl







BUI

5.0 as/1
fieoattcic




















GEIIUL IIFO1BUIOI

fcamcca at 25 C »a 7SO a* Bg
(>.«t occirrtne*
lover aid afpar oae-Sigaa limit* 2.7
" "
BaalthT* IB— 35 fr old* BO&saolclngr
attaa black* aad caacaxiaas*
Chicago. It. KigiilT caatroll«9
axpaciMBttl coiditioaa^
IBUTB: llCOBOtS; IIUWIS; H>HMS;
CILOBmTED STDBOOBBOIS: TOtlTILB
OMUIC CClICinDS; HU1TB BHIBIS;
iiBiUTioi; amioiisri: BiTteoims;
tcroimoi iirostriB: IIBII tuts

Ifl cfclohoaaol (aataboUta}
Data also on solm.t* IB factocy air

Icckara IB shoe teetorf IB Italy

tBIBB; BTD10CU1OB3: BJRUO1IXES;
lt»lT; HDoniJll ITIOSFBIBtS;
imsmii neiEii: IIB potmriai-.
ccciruioni Di«isis
IIFEUVCE

l-wtenrMkl. t.t.
SmnBio, «.B.
O'leill, B.J.
Join*! of InalTticil
ToiicologT 3:225-23*









BrugsoB** F.
FaTaB* I.
1980
Toilcologr and applied
Ptarneol04T 53:220-224



              MtftTl~
  10B-87-2
  C1-BU
  tl *g.10, » -116.» C, BV 100,3 C. TT «» » Eq at 22.0 C
II3S«
Inath


EMOSVBB iOOTI




8IVBS


lire Bat
OF cuts
*


III6B
lot 4*t*ct«d-13«0 ag/ht


Bill
1.6 ««/hr


SCIEUL mOBMTIOl f
CeipoMd fcoi aafcaoia orlgia. lo
cthat latailt gitaa
B«aUhT allltarr a>9 civlliaB
«lplOTM>> 0.5. llr IOCC* School Of
laroapaca Ratlcia*. ages 23-*7 ji. 3
not«n.
minis; cBiosiBiTSD naaacaBBOist
CBIOBIKS oiemc COIPOOIOS:
CBtOBOBEIIlKSt FITOSIlt COBPOUIDS;
IBZITB: HCCBOlSj THIS; 1BC1TS
BETESBICE
-
COBkl«. J.P.
Caap. D.J.
»*lch. B.I.
znvlronwattl Health
30 t2(: 250-295
i

-------
crelohaiase, 1,2.3,a,J.«-»axac!>loco-. alpha-  (6  CIJ
'--'"---ane, 1,2.3,»,S,«-ka)zachlaro-,  (1alpha,2alpha.3beta.«alpha.5beta.6b«ta)- (9
   MO.S3, 8J 1S9.S-UO C, BT 289 C, »P 0.02 u Ba, »t  20 C























fISSVS



J««2
Blood.
MtU









IUOSOBB soon




















1
1
1 1
1 I
1 3t«3 1
1 Hood, |
1 >kole I
1 1
1
1





1
1
1
f
1




,
1
1
1
1
1
*
39t»
Bilk





























lumicti.
HBfBGD


BC



















BVBBBB i um RUI i snmi aronutoi i unmet
OF CIStS 1 1 t
1 1 1
1 1 1
•I » of 19 I a) 1.*-B.3 •o/l a| 2. S af/1 1 *) 6e*eral population - Continental t Kraathacker. 3.
b) 8 o* •« I b| 0.7-2.5 aoyi b) 1.3 ag/1 1 *o«th (»rban) 1 lleble-RoUuh, T.
O 1 of SO 1 c) 3.4-29 ooyl c> 9.2 go/1 1 b) eeieral population - island I Ktal-), C.
dj 28 of 14) 9.2-157 ««/!
28 |
f
1
1
|
1
1
1
1
1
<
|
1
1
1
1
1
I SO-BC a| t« | •) lot detect*!
1 b) 2 I b) lot applicable
1 1
1
1
|
1
d) 38 ag/1 | (ratal) I TkaleeTic, B.
Geometric Mans I c) Sipoaod workers - Continental 1 Miner. I.
1 iccth (drban) I 1910
1 d) Xxposed vcckan - Continental t latamatioaal archive
1 sootb (arban) 1 of Occupational and
1 1 EntironaentU Malta
1 Oeneral ponalatlaa. a?<* «-79 rr. 1 «5: 2 17-220
1 occipatlocallr exposed >ock«n. »g»f 1
1 2C-62 ?r. IiaoslaTla. (
1 1
I ivaostmi: MOOD saas: DBB; BOB; i
1 EM; CBLOSlliTED HTOBOC»EBO»S: |
I cnotitz oteuic COIPOUSDS; (
i iKicnorocicioBmu; PISTICIDBS; i
l occopiTioiii nzuos; PESTICIDS i
1 1ISIB1HS; P05011TIOI RPOSOSI; BHB11 I
1 IttlSs VtStt UtttS I
1 1
1 1
a) lot detected I a) love Canal residents | Bristol, o.v.
b) 0. 1 09/7 | b) Tolnteec*. 1 positlre 1 19SO
1 man of polltiTe sasples. Ll»lt of I IP1-600/1-80-03S, «0
1 •eaaiireBeikt. 0.0a7 H4/9 I pp.
1 Cloself watched, sisiltaneons control I
1 sanplei vere got proiided for I
1 analysis aloaq «ltk tkose fro* the 36 1
1 1 1 lore Cull area residents saaplcd. I
1 1 1 lacking Maninofal control at 1
1 I 1 literature data relatin to the I
1 1 1 significance of the Ion residues I

(
1
f
1

1
1
1
|
1
1




CO- 1C
GC/BS


























i











1 1 found la the field «»pl» analyzed. I
1 I 10 definite coacllalon* can be drava 1
< I fzoi ti« results repotted, |













< 0.1 o»/*9











1 1
f fesideats of re* Tor It. Controls, I
1 caplorees of the Snrtroueital I
1 Protection tamer »n4 aniTarstty I
1 «t«de«ts, forth Carolina. |
1 1
1 III T01K; WOKH CIROIUI; B1OOD; |
1 9MSWMJIT HrrBOJSj C9LOBITC OIXStBIC I
I ccatoonDS; ctia&otztssKS: \
1 iixicRioicBtnziz: POIICBIOBIITITEI) i
l ntitmss poptrHTios SIPOSUSI I
i i
l i
Wot applleafele I lactatlif lothcn 1 Kodric-Salt. S.
1 < Salt, t.
I 17-«1 TT old* froa $lanaia Province, 1 Clie, K.
1 TvgoslaTla. 1 1980
1 1 Pesticides 1ooltorin
-------
CfelokuaM, 1,2.3,«,S.6-li«iackloro-,  beta- (» CIJ
Crdektxu*. 1,2,J,*.S,6-t«nckloro-,  (1alpaa,2beta,3alpfca,*Jbet«,5ali>ka,6beta)-  (9
3M-8S-7
Cf-B6-C16
If 290.83, M 31*-31S C fsabliaes), BP CO C at  0.58 n Bg,  TP 0.005 » Eg it 20 C
TISSUE



3665
IdiBoaa























36 6€
Ulpose










3M7
lolpose










IPOSOH BOOTS




















































uumcu
BBTBOD



























ec























iD9Bm
or cists



























60











a) 27
») 1
C) 1









UK*




























0.23-9.79 ppa











a) lot firea
B) Bot ei»ea
c) lot alien









nn t GEimi lifotBino*
i
i _..._.... . _ .
i
1 l«le«
1
I liposed persons IB tke United States,
I tke letkailnndB, sseden, Israel.
1 Japan, VSSB, Poland* Gernanf* India,
1 Balgarla. Pakistan, lastria.
1
I elevated seTae cholesterol, abnornal
1 Its*, or iapalraeat of Bearcaascolar
1 faietlOB a(t«r acvte ezpo*ata to
I cciSi.Mti.OBi of pesticides, tat »ost
1 data sho« no adTerse effect* alter
1 lca«-tecB occupational exposure.
1 1DS1BT1; B'JISISU; GJBS1II: noil;
| IS&m; 31?l»; ISTHEB1MDS: IUI5TM:
1 tciiBD; iissu: svcDii; UIITID
| STlttS; IBIPOSE TISSOE; BlOOIi BLOOD
| tllSBl; »IOCI StMl; E3TTBBOCTTBS;
| HOSOCITES; BILK; UBISB; BET1ES-.
I I»HH HUlBtS: OCCD?»TIO«U BKUOS;
| K>*nmO« IIMSOK: ISOPtlSBS;
I (ISTICIDIS; CBlOtllB OBSalTC
I CCHOV1DS
1 .
I
0.7« pps 1 laripkeral kidnei fat, roatine
1 patkoloqlcal eianinatlons
1
1 iqes « ao-ej jr, Belaivs
I
I fllSIO!!; kOTOPSIBS; >9IK)SB 1I3SOE;
I SIOICCtHHI»TIO»; PESTICIDES; DDO;
1 cm: on: BIILDBI*: ISPTICIIOB
| tfOTIH; SEllCBlOBOBEltraB; mguS:
1 cnoitis oBeinc conaams
i
I
a) 1S.7 » or - 19.78 I a) tospital patients
ppa |k) 13 TT old Caaale «itk Tasko
b) 0.*7 ppe, fat |c) as yr old aale wltfe chronic PCB
basis 1 foiaoAlnq
c) 2.0 ppa, fat basis 1
1 Japaa
1
1 IClYCIItOBmtlD BIPBEITLS: 1ST;
1 BillCBLOtOCYCLOBItllE; BLOOD fHSB»;
I SYSTER; pzsuciois: utross nssns;
1 IIVR; KID1IITS: OBMIU9
1
lirEEEICE



eicaaannv H.B*
BacOonali, I.E.
»77
Icatozieoleor »d
EaTirOBBeatal Safetf
: 89-1 10



















De-taBekaeere. I.
Stearbant, f.
Terstraeten, B.
Kips, S.H.
1978
loileoloolcal Earopean
leseareh 2(2) « 93-98





Isone. 1.
Ibe, S.
Takasatsv* H.
aoki, >.
Rikl. S.
Palirara, K.
197S
Tvkaoka Heiieal Journal
6* {10: 6 10-6 16



(Hit USB)

-------
CTCloaexane, 1,2,3, *.5,6-hexechl0ro-, beta-  (•  CI)
Sigijs""*' '•2*3'*«s'*~h"»e*loro-,  (1alpha,2beta.3alph»,abeu.5ali*a,6beta)- (9 CI)

C«-IC-C16
II 290.83, R( 31V-J15 c  (sgbliaes), BP CO C at  0.56  u  Bg,  TP 0.005  as Bg at 20 C
                                                                                      (COfTIPOlD)
HSSffl

38«8
Blood










|
|
1
1
|
1
1
1
1
1
1 1
1
1


38 «9
Blood,
plasna




|
1 1
1 1
1 1
1 1
1 1
1 1
1 1
1 3870 I
1 BlflOl, i
1 (kola 1
1 1
1













































mosaic BOOM

















1UITTIC1I | suites 1 B1IGX
RETROD i or cisss i
1 1
J 1
t 1
1 1
1 1
1 1
1 1
1 f
1 1
1 1
1 1
1 1
1 1
1 1
1 1
i 1
1 1
l 1 1
1 l 1
1 1 1
l l l
i J
1 1
BUI i ert BUI nroiMTioi
J
1 >
1
1 Izposet pezscas ia the onlted States
1 tka setherlaids, Svedon, Israel.
I Japan, USSR, Poland, Gersanv. India,
1 Eilgarla, Pakistan, instrla.
1
1 Reported cases of hypertension.
I elevated serm cholesterol, abnornal
t IFSs, or iapalraent ot aearoanscalar
1 function after aente exposnre to
1 eoatinatioas of pesticides, bat sast
1 data shov no adverse effects after
1 long-tern occapatlaial exponre.
1
1 lostsiit BoieiBia: era^nt; KDU:
| ISmSl; J1P1I; IETRESI.UDS: PIKIST1
i JOHID: EOJSJ*: SVIDEI; OBITED
t STITBS; jiDIPOSI TISSUS: B100D; BLOO
| FI1SU; BIOOD SEBUB: SSTTBBOCrlES;
| XfOITOCTTSS; Et£K; VBIVl; BEfTZV;
1 HtllTB 3IZIBCS; OCCVP1TIORU R1Z1BPS
| | | IC7DUTIOI UPOS01B; IIOPIISRS:
( | t I15TJC1DIS: CB10BIIE OBG11IC
1 | I CCIPOBUDS
tit 1
til 1
1 a) 2« la) lot given a) 1«.« » or - 1O.45 | a) Hospital patients
1 b) 16 | b) lot given ppb I t) Enacitted persons
1 O 37 J c) lot givea b) 25.5 t or - 22.01 I c) loa-eaaciated persons
t d| 1 It) lot given ppb I d) 13 rr old f«nale vith Tasbo
1 •) 1 I e) lot given O 14.3 » or - 11.00 I e] 2> rr old nale «lth tplastic
J 1 P"P.b f •••etift And stonicich Cttnc*Bi?
II d) 19 ppb I
1 e) *30 ppb | Japan
1 1 1
1 1 1 I01TCB101IIITH> BIPBEITIS; BDT;
1 1 1 BCI1CBXOBOCYCI0RR1I3; BIO08 PlaSBl;
1 I i iropusus; Jipi>; atsnoinssnm.
1 t I SISTER; P-STICTDIS; JDIPOSE TISSUE;
J
1
1
SC-EC

















































a) 3» |a) 0.2-O.C sg/g
VI 11 | b) 0.2-1 ng/g
I
























1 ZIVBR; BTXDIEYS: OREITUR
1
1
a) 0.3 ng/g | a) love Canal residents, 50* (17)
b) 0. S ng/g I rceitire candles
1 tl Tolonteers, 551 (6) positive
1 Maples
1 Bange and teas of positive sasples.
1 licit of aeasnresent, 0.21 no/g
r Closelr natcbsd, sinnltaneoas control
f sasples vere not provided for
1 analvsis along vith those from the 36
I love Canal ares residents aaipled.
1 lacking neaninvfnl control or
1 litcratare data relative to tie
1 significance of the lo« residees
I fensd in the field sanpl«s analyzed.
1 nc definite conclusions can be drain
1 fios the results reported.
1
1 Residents of lev lork. Controls,
j etplofees of tke Invironnental
I Protection Igencr and inivecBitj
I etedents, forth Carolina.
1
| 111 TOM; HCFTH CtEOUti; BLOOD;
| RllStnEHEIT JITBOBS; CHLOBTIE OKU1C
| CCBKHHDS; CH08OB*IXSII$:
1 «!i»cstoacsiHB»i: POITCEHOBIW ITIB
i
BtmnrcB

Deichaann, J.B.
lacDosald. I.E.
.1977
Ecotozicologr and
Environaeatal Safety
1S89-110





















Inoae, r.
Ibe, S.
Takasatsa, R.
loki, 1.
Blki, S.
W75
Fakaaka ledlcal Journal
66(10:610-616







ristol, D.I.
980
Pl-600/1-80-036, 40
P.























                                                                                 (lilt IIGB)

-------
t,2,3,a,S,«-texackloro-, beta-  f« CI)
t,2.J,a.5.S-k*Mckloro-. (1»lpka,2beta,3«lpka,,«bet«,5alpka.6b«ta) - (9 CI)
 CFdoaezaae,
Crclohezane,
319-8S-7
CC-BC-C1C
•I 290.83. IP 314-315 C (siblisea). BP 60 C at 0.58 u  H«
                                              TP 0.005 » tg at 20 C
                                                                         (C01IIIUED)
lissni
3871
I idler
3872
lint
1
|
3873 1
lilt
387*
Bilk, fat
3875
Oceatss
xiposTOK BOOM

I
1
1



1I1LRICU
nraoo

1
1
i
GC-EC
oc/ss
GC-BC

man
OP C1SIS
1
1
10

») 1
b) 1
Inez
t applicable
ot applicable
a. 1-18.6 o«/kg
a) lot film
b) lot given
c)  or - 1.51 I after iell»«rT- 5esidents of Osaka 1 of Occapatiooal and
ppa 1 Prefecture, Japan, »aried fllets and I ZnTiroaseatal Health
f) 2.07 « or - 1.00 | (nviroBaental conditions. | 43: t-15
PPa 1 |
1 oiPH: iDoiTS; itctiTioi: niK: I
I BIOCCTBOIITIOB; PE3TIC1DIS; OB5HIC |
I CEIOSin COBtOOlDS; POLTCmOBIUTE!) 1
| EI»B?ITLS |
• 1
1 1
a) 23 ppa (fat basis) | a) 73 YT old i*l« vltk coloa caacer I Inoae, T.
b) «.1 ppa (fat | c) 66 rr old aale with stonach cancer | ibe, s.
basis) | | Takaaatsa. (1.
1 Japan | loki, ».
1 | niki, 5.
1 I01YCELOBIIITID BIPBZ1ILS: DDT; | Tnjinara, 1C.
1 EfTtClIOBOCTCIOBITilt; BLOOD PLISBl: 1 1975
I IZ07LISJS: J1P1I; GlSTBOIlTESnilL I Tuknoka aedical Jonraal
1 SIStEl; PtSlICIDBS; 1DIPOSZ USSUX; I 66(10:610-616
1 I1TZB; KI01ETS; OSIITIB 1
• 1

-------
    Cyclohezane.  1.2.3,«,S.6-bexachloro-.  delta-  (8  CI)
    Cjclohezane,  1.2.3.*.S.6-hezacfcloro-,  {1alpha,2alpha.3alpha,*beta,5alpha,6teta)-  (9 CI)
    31$*86~fl
    ce-B6-ci«
    H» 290.83, ft 141.5-1*2.0 C, BP 60 C at 0.3* mm  Eg. vp 0.02 mm Bg at 20 C
IISSOI

3876
Blood.
• bole






1
1
1
1
1
1
1 1
1
1







EIPOSOIE BODTE 1ULYTIC1L
BETBOD

GC-BC



J
1
1
1






|
|
1








1 Bragg*
1 OF CASES
i

a) 33
b) 12























*"se

a) 0.1-0.2 ng/g
b) lot applicable























•Elf | GIIIB1L IIF01B1TIOI
1
1
a) 0.2 ng/g I a) Love Canal residents. 9* (3)
b) 0.5 ng/g 1 positive
1 b) Volunteers. «« (j) positive
I Bange and Man of positive sanples.
1 Ilsit of aea sure neat. 0.12 ng/g
1 closely natched. sinnltaneons control
1 sanples vere not provided for
I analysis along vita those fron the 36
j tove canal area residents sanpled.
I Lacking neaningfal control or
1 literature data relative to the
1 significance of the lov residues
1 found in the field sanples analyzed.
1 no definite conclusions can be dravo
I fron the results reported.
1
1 Besldents of Ren Tork. controls.
| eaplovees of the SBVlronsental
I Protection agency and university
1 students. Vorth Carolina.
1
1 iti TOSS; lorrn cuoiiwi; BLOOD;
I BIlSVBERni BETBOOS; CBLO8IIE OBG1BIC
| CCtPOOIDS; CBIOBOBEB2BWBS:
| BIIICB1050BIIZEIE: POLTCHLOIII1IE9
I ciPBirrts; popoimoB ETPOSBBE
i
IEFEBEBCE

Bristol, D.V.
1980
EP1-600/1-80-036, *0
pp.





















Cjclohnane.  ,2.3.4.S,6-hezacbloro-, ganna-  (8 CI]
Crclohezane,  .2,3,4,5,6-hezachloro-, (1alpha,2alpha,3beta,*al;ha
-------
 Crcloluave.  f,2.3,*,5,<-aexacaloro-, gmmmt- (8 CI)
 Cyclohexane,  l,2,3,*,5.«-a«acaloro-, f1«lpk«,2alpha.3bata,4«lpk«,5«lph«,«b«t«)-  |» CT)

CS-B6-C16
It 290.95, BP g-aua-isoser crystals 112.5 C, SP 323.• C,  176.2 c it 10 mm Bg.  TP 0.1« •• Bq at *0 C
                                                                                      (COETIBDED)
IIS5BZ
3878
IBlOtiC
fluid
3879
Blood
3880
Blood.
s«ma
3881
float,
vbole
IPOSDBS BOVTZ




lEaimciL
SETS CD
-EC
8C-BC
oc
SC-IC
B0SBSB
F CIStS

25
IS
10
a) 2 of 19
b) 29 of
SO
c) 28 of
28
a) 33
b> 11
11(61
9-61 ppb
) 7-39 ppb
I 15-75 ppr
1 W-136 ppb
a) 2.1-6.7 ug/1
b) 3.6-30 ugA
c) a. 5-98 ug/1
a) 0.1-0.6 ng/g
b) 0.1-0.3 ng/g
Bill 1 CEIIB1L XEFOBB1TIOB 1 lErElEICB
1 1
1 1
1 1
7.12 ppb 1 50 positive speciMBS I Saxena, I.e.
Geoaetric I I Seth, T.D.
1 Pregnant soaen, siiilar ID 1 Bahajan, P.I.
1 locioecoaoalc level and dietary 1 1980
1 habits, lo occupational or 1 International Journal
1 accidental exposure. LUCXBOV, India 1 of Environmental
1 ' 1 Inalytical Chesistrv
I flSTICIDlS; CHIOBK1TED HTDBOC1BBOBS; I 7:285-251
I CBLOBIJB OBGltTC COBPODIDS; ODD; DDE; I
1 Ell: IIDIl; FBE6I1BCT; 1B1IOTIC |
1 ftOIB; P11CIBT1 |
1 1
1 1
) 18.9 * or - 8.8 1 a) Controls, full-ten pregnancies I Sanaa, B.C.
ib | t) ire-tern pregnancies 1 siaaiqai. fl.K.J.
1 39.7 « or - 1*.3 I c) Spontaneous abortions at less than I Seth. T.D.
pb 1 8 «k | Krishna Haiti. C.B.
) 73.3 » or - 32.2 I t BhargaTa. l.K.
ppb | icalthYf non-expose4, pregnant toaen. j natty, 0.
I ages K-32 TT, InSia. | 1981
1 1 Joamal of Analytical
1 IIDH; 4BOBTIOS; 1DHUS; TITOS ; | Toxicology 5:6-9
1 BLOOD; 711CIR1; CORMB1TITB |
1 tfllTllTIOIS; CI10BXI1TBD I
1 BTCBOCllBOS; CB10KIBB OXS1BIC |
1 COBtOOBDS; I1SECTICID5S; P1SHCIDES; |
I IBSTtCIIB 11SIDOIS; POPntaTICI 1
1 UPOSH1B; P1I6B1BCT |
1 1
1 |
a) 3.8 vg/1 1 at General population - continental 1 K rant hacker. B.
b) 10. » ng/1 I seath (urban) | llebic-Kolbah, T.
c) 26 og/1 I t> Sxposei workers - continental 1 Krall, B.
Geoietric leans | aorth (orban) | TkalceTic. B.
1 e) IzposeS workers - continental I Reiner, B.
1 scuta | 1980
1 1 International archives
1 General population, ages 6-79 yr. I of Occupational an!
1 Ceeupationallv exposed workers, ages I Environsental Health
1 20-C2 yr. Yugoslavia. I (5:217-220
t TUGOSltVIl; BLOOD SETOB; CBLOHIB1TED |
1 BIDBOC19BOIS: CHIOBUS OS61BIC 1
| COHPCWKDS; HDD: DDE; DDT: 1
I BIIlCHIO8OCyC10BEIlBI: PISTICIDHS; |
1 CCCOPITIOBU HaZlSDS; PESTICIDE I
I BI5IDOIS; POEOIATIOI EIPOSDBZ; ROB11 I
1 1DTIS; 18B1I 1BE1S |
1 1
1 1
a) 0.2 ng/g I a) tove Canal residents. 21! (7) | Bristol, D.I.
b) 0.2 ng/g \ positive I 1980
t b) Volunteers. 36" (») positive | ISI-600/1-80-036, 40
1 B»ge ana nean of positive sasples. I pp.
1 lilit of neasureaent, 0.068 ng/g I
I Closely latched, sinaltaneonE control 1
I saiples were not provided, for 1
I analysis along with those frcs the 36 1
1 love canal area residents saapled. 1
1 lacking seaningful control or |
1 literature data relative to the I
1 significance of the low residues 1
1 found in the field saaples analyzed, I
1 ao definite conclusions can be drawn |
1 fros the results reported. I
1 1
1 eaployees of the Environaental 1
1 Frotection Igency and university I
1 students. Sorth Carolina. 1
1 III TOBK; BOBTR CaSOLIBl: BLOOD; I
1 MkSnREHERT IBTBODS; CRLOBIBE OBGAHIC I
1 CCBPODIOS; CBL030BEBZ3BES; |
1 BITlCRLOBOBtlZSRE; PO1TCBLOBIBATED I
1 EIPBIWT1S: CCPHL1TIOB EXPOSOIt! |
(HIT P»S!)

-------
     Cyclohexane,  1.2.3.>.5,K-heiachloro-. gam- (8 CI)
     Cyclokexane.  1,2.3,a.S.6-lieiachloro-, <1alpha,2alpha.3b»ta,(alpha,5alpka.6beta)- (9 CI)

     CC-IC-C16
     II 290.85,  BP ganna-iawBer crystals 112.5 C, BP 323.* c,  176.2 c  at  10  m*  eg.  TP 0.1* » Bg at «0 c
                                                                                           (COBTIHUED)



I
1
1
1
1
1
IIS30!
3»82
Bilk
3883
Placenta
388* I
Placeata |
I
1
EXPOS9IE IOOII
Ingest ion
1
1
1
I
1
1
numcu
IUTHCD
ec
ec-sc
oc-xc
IBH8EB
OF CIStS
a) 21
b) 2*
c) «5
d) *S
50
) 25
) 15
> 10
BUGS
a) 0-0.061 pp.
b) 0-0.270 ppB
c) 0-0.270 jpe
A) lot given
62-1631 ppt
) 2-23 ppb
) 7-*1 ppt
I 10-6 6 ppb
Bill | SEBI11I IIFOtBaTXOI | BBPEBBtCE
1 1
1 1
a) 0.011 ppa I a) (oral Bothers, fat basis I Pozo Lota, B.
b) 0.037 PPB 1 M Orbaa aotbers, fat basis I Herrera Karteache, a.
c) 0.025 ppB | e) 111 Bothers, fat basis f Polo Yillar, 1.1.
i) 0.000* ppB I d) 111 Bothers, .hole allk basis I topez-Giaenez, B.
1 Data for sni of all pesticides and I Jodral Tillarejo, 9.
I ccifarisons vita Tains of other I Iglesias Perez, J.
1 laresttjaton qlven | 1979
1 1 Berista Sspanola de
I Inrsiag aoth«rs froa Cordoba region, I Pediatria
1 SfaiB | 35(206) :93- 110
| SF1H: IDOLTS; HUE; CHLOIIIZ OBG1IIC I
| COIPOmiS; PISTICIDES; IGBICDlTrei; |
| iUSlL »B!IS; VBB1I aR31S |
1 1
389.6* ppb I *l positive tpeciMBS t Saxena, n.c.
SeoBetcic | I Seth, T.D.
I Freaaant noaan, siaiiar in j Bahalan, P.I.
1 aceioeooaoiic level and dietary I 1980
j cabits. no occupational or I International Journal
j accidental exposm. Lucknov, India 1 of EnTironaental
j 1 analytical Cheaistrr
| flSTTCIDIS; CHLOSIlllTSO HTDBOCUBBOKS; | 7:245-251
I CEIOBIIS OB«I1TC COBPOOUPS; BOO; DDZ; I
j CtT; IIOII; PIE6I1ICT; 1BIIOTIC I
| I1UID; PlICIRI |
1 1
1 I
) 8.9 * or - 4.3 ppb | a) Controls, fall-ten pregnancies I Saxena, B,C*
) 20.* * or - 8.8 j i) Pre-tera presiaancies I Siaalqui, S.K.J.
pb | c) Spontaneois abortions at less than j Seth, T.D.
) 30.6 » or - 15.5 I 1 »k (inclad«s fetus) I Krishna flnrti, C.B.
pb I I Bhargava, a.K.
I Bealthy, non-exposed, pregnant voaen, 1 Rutty, D.
I aoes 18-32 jt, India. I 1981
I | Journal of taalf tical
I IIDI1; « BOB! 10» ; aOOLTS; FETOS; 1 Toxicology 5:6-9
| EtOCD; PI1CIIT1; COBPJS1TITE I
| ITJLOITIOKS; CHLOEIIaTED I
1 BIDBOOBBOJS; CHIOBIIE OBGtllC 1
1 ccnpotnos: IISECTICIDSS; PESTICIDES; I
I FISTICIDt BESIDDES; POPDL»IIO» 1
| tlPOSDBE; PBE6I1ICT I
1 1
CTdoaexagel
1C8-93-0
C6-H12-0
II 100.16, If 2* C, BP 161.5 C,  TP  1  BB Bg at 21.0 C
TISSUE
3885
Ereati



BIPOSBBE BOUTI




iUIITICal
IJZTBOD
SC/HS



OF C»S!S
8



»IGE
lat detected-I.C ng/hr


(MT.1
1E11
0.5 ua/hr


S»GE)
Glimt IIF01I1TIOI
CCBcaul related to aornal
netabolisn. lo other details given
Cryogenic saapling teehnigae.
Sealthv ailitary and civilian
enplorees, D.s. lir Force School of
lerospaee iledieine, ages 23-*7 yr. 3
SBOkers.
EtlTWES; CBIOBUATSB HTDBOCaDBOIS:
CBIO'IS* OSGIHC COBPOniDS;
IBI1TH: aLCOBOLS; TBT1S; AEHITS

BEFE8EICE
Conkle, J.P.
Canp, S.J.
Belch, B.E.
1975
archives of
Environmental Health
30 (2): 290-295




-------
CjcloaeiMol
1M-tJ-0
«-II2-0
M 100.1C. tt 2« C, 0 Kt.5 C. T*  7 M V? at 2t.O C
                                                                                      (COBTHOED)
1I5SVI
3866
Breath












IWOSOSI BOOT*














iBunicu
BBTBCD
cc-»s













B01BCB
or cisss
S* (387
saaples)












MBGI
lot girea













BB1B
2.6 (9/1
eeoutric












mnu iBfosBivxoB
Manna at 25 C and 760 u 14
«5.6» occurrence
loier and upper oae-Sigia Halts 1.03
aid <.« no/1

Bealthr, 19-35 TC old, a«»sw>kii<|.
vrtu blacks and caoc»siana.
Chicago, U. Blqiaiy conttollei
aifctiaaital eondltioaa.
miTE; ticcHLs: iitisois; IDQHS;
CBLClIIaTID tIDiOClIBOlS: TOHTI1!
CIS1ITC COSfCtWDS; BEllTB BltlBBS;
1I11I1TIC1; BSTlEOlISfl; BniBOlTTIS:
tcraimoi inosoM; TUB in »BE»S
1E7Z2EHCX
Kratoszinaki. B.I.
Bnuaan, G. a.
O'Hsill, a.j.
1979
Jovrnal oX inalrtical
Toxicology 3:225-23*








1162-K-8
Cn-H12-06
Bl 312.3. » 268-269 C
                                        <1)b«BiopTra»-1.11-aion«. 2.3,6aalrha,«aalp1ia-t«tcatiTdro-«-Mta(UT- (a CI)
                                                                                                            )- (9 CI)
TISSHI
38)7
Hood.
EtIM


BUOSOIE BODTB
laqastion


llaLTIICll
8BTHOD
BSLC
IS


•oHtm
or cisis
1


files
lot applicable


•nil
3.39 »q/al


GT1EB1L IIPOlRaTIOI
CB adaissioD. itlatoiin aoarce
•HkBOII.
31 it old black patlmt with hepatic
carcinoaa.
at latoiia-lB(air«d iaaone ceepoaoe.
line eaaccE. Clotting tile
alfeetal, deitt caaaad bf heaorrfcaqe
altar ncqecf.
JtClTS; C1SS EISIOIIBS; IBOFUS9S;
HOOD SEBTra; ITLatOIXIS; CIBCIIOCBII;
IttU« HITlBtS-. IOOB COHTIHIIVTIOS
1BFIBBICB
tr«r. B.S.
Bljes, 1.1.
1980
ZBTir<»Beiital Be search
22:«00-ao3


             *. latkTl-
  «€-37-7
  C«-B12
  El e«.1«,  HP -H2.3 C, B? 71.8 C, TF 100 la Bo. at  17.9  C
IISS01
3888
Breath

1


iBiinicit
BETBOD
OC/HS

BBBBSS
or CISES
8

IUGB
Bat detected-11.0 ng/hr

B!i« 1
1.5 ag/hr


Ccifonid related to nocaal
•etabolisi. fa other details gives
CXTogealc aaipliag tectalgM.
BcaltliT ailitarr and clTillaa
eeplOTees. o.s. lie TOTCC School of
lecospaee RedleiBe. ages 23-47 jr. 3
tmiBSS; CSIOBIBITEI BTDBOC1BBOIS:
CBlOtIRE OB6UIC COBFOWDS:
CBIOBOBEBZEBIS: FLOOBII! COBPOVBDS;
IltlTH; HCOBOLS; TEI1S; 1D01TS
BBFBIEICE
"conkle, J.P.
Caap, B.J.
Belch. I.E.
1975
IXChiTCS Of
OriroBaeatal Health
30(21:290-295


-------
     C5-B10-0
     II as.13, BF -19 C, BP 139.5 C
T1SSTII

3889
Breath








1
1
!
I ElPOSmi BO1TZ
1
1













1 lliLIIICtt
1
|
I CC-BS
1
(
f
1
1
I
t






IIXBE1
OT CtSBS

5« R87
saaples)











BJISI

lot gir«












BEir

0.329 ng/1
SeoMtric











CXinil II'OMITIOS

Beasorea at 25 C aid 760 is Bg
8.5V occurrence
lover and upper ane-Sigsa Units
0.0«9 and 1.59 ng/1

aeilta-r. 18-35 vr old, oonssoklng,
oilsn Hacks aid Caucasians.
Caicago, II. BigidlT controlled
•npcrineatal conditions.
E9HTS: tlCCCOLSj 1ILIIOTS; 1DVLTS;
CB10BIUTID BTDBOCaBBOK; lOXaTILI
cosine coftants: mm BIZAEBS;
IBRIUTIOB: BETIEOI.ISB: HSTisoirrss:
POTULtTtOI ZIPOSD9S; nBS»» »EE»S
JiriSElC!

Kcotoszvnski B*t
Bma«aaf G. H.
O'Rvill, B.J.
T979
*7&QfBa:2 0-f AoalTtlca]
loxicologv 3:22S~23«







   Cjatiu
   ;«64S-67-»
1
1 3890
1 Kail
f



J
1
|
1
j EXK>5Sft£ BO ffll
1
'








1IU.TTICU.
JSTBOO
ColorlsetrT








OF C15SS


1
1
1
I
I
1
J
1
BUS!
a) 10.6-16. 2S
1) 10.7-is. »jr
zirr vt







1 Mli
I
a) 13.3 » or - 1.61
b) 13. S * or - 1.««
Dry *t





1
i
G11EB1L irFOBIaTIO*
a) Bxposed verk«rs
t) Controls
to association betveen dnratios of
exposure and crstiaa content.

lork«rs, 22-52 11 olfl, in vanaiion
factory, rinlaad.

IB! tO tCIDSj OCCVP1T10B1L BHASDS;
FCFDUTIOI SIPOS01I; I1ILS; 7IS11BD

lEffBncl
KivillotO, *.
Fakarlnen, 1.
1980
International Archives
of Occupational aai
•6: 179-182



112-31-2
CK-B20-0
H 156.27, H -5 C,  BP 2*3-209 C. TP 1 •* Hff at 51.9 C
IISSOB
-
3091
Breatk












zzrosasz soni














1 UI.TTICII
SC-HS













or cis is
M 1387
saaplee)












IU6E
Bot given













*"'
0.261 ng/1
seoxatric












GE1IS1I IirOBSaTIOB
Bea tared at 25 C and 76D n Bg
5(. 1* occori-ence
Icntr »nJ apper oae-Signa Halts
C.0t7 an$ 0.700 nq/1

EealtkT, 19-35 rr oie. aonsnoking.
ntlan blacks and caacasiana.
Cblcaqo, II. EiqidlT controlled
•ipcriaeata) conditions.
ElflTH: IICCBOLS; IlLHOIS; iDOlTS;
cnoilRaTED ETDIOCkVSOBS; TOUT RE
CIG1ITC C09KOBOS: l^alTB ElUEES;
IIHltlTIOl-; BITieolISIj BBtlBOtrtSS;
POT1HTI01 1IWSB?E: 1JBM 1B11S
ISFE1EBCE
KrotosxT&skl, 3. E.
Brnnean, G. a.
C'leill. B.J.
1979
Journal of analrtlcal
Toiicoltxji J:225-2I«









-------
 12*-ta-5
1X exposed residents had bnrnllke
skin lesions, sone with cbloracne
ITILT; IDOIfSCETITS: MOLTS; US!
EISTOBItS; CBlLBSei: 1DIPOS! TISSO!;
EBtll; KIDIITS; LITIB: LDB6S;
fllCSHS; RI11TH HnllSDS; IVDUSTBIU.
1CCIDHTS; IIOPLaSSS
-
IntopST tissue. Bepre seats cat
recovery
?•• it oil vonaa »ho died of
pancreatic carcinon 7 no after
industrial accident in Seresc, Italy,
111 exposed residents had bernllke
till lesions, sose "ith caloracne
IT11T: IDOllSCeilTS; IBOtTS; CASE
BISTOBIBS; CBItDSE*: iBIPOS! TISSUE;
tBi»; moms: LITIB: LDBSS;
EHICBI15; BULTB BnZ»BS; IBDUSTEI1L
UflBEICS I
Seggiani, 0.
1990
Joarul of Toxicologv
and SnTironnental
Health 6:27-43


' Beggianl, s.
1980
Joaraal of Toxicology
and tnvironnental
Health 6:27-13


                                                                                        (•SIT PICK)

-------
Dlbeniofnran. 2,3.7,8-tetrachloro-
•1J07-31-9
C13-B«-Cl«-0
BR 306
                                                                                      (COSTIBUBD)
TISSBB
3695
Kidney


3896
liver


3897
lung


3898
Pancreas


EIMSOSB BOOTB
Xngestion


Ingest ion


Inqestion


Ingestion


IBalTTICaL
RETROD












RUBBBB
Of CASBS
1


1


1


1


BUGS
Rot applicable


Mot applicable


lot applicable

. _ _ _
lot applicable


BBaB
O.OH ppb


0.15 ppb


0.06 ppb


1.04 ppb


GEBEBaL IBVOBRaTIOB
Autopsy tissue. Represents 60*
recovery
5? yr oil HOMO who died of
pancreatic carcinoma 7 BO after
industrial accident in Seveso, Italy,
1976
All exposed residents had burnlike
skin lesions, soae vlth chloracne
mil: iDOtBSCBBTS: IDOI.TS: C»SB
FISTOBI8S; CBILDBBB: IDIPOSB TISSUE;
tBalB; KIDBIIS; 11788; IHBGS;
EISCBS»3; BBILTR HIZISDS; IIDDSTBIaL
iccioirts: iiopLaSRS
lotopsr tissue. Represents (VI
r«eo*ery
^5 yr old voian who died of
pancreatic carclnoia 7 no after
industrial accident in Seveso, Italy,
t976
All exposed residents had bnrnlike
akin lesions, soae with cbloraene
ITUT; IDOLBSCBBIS; 1DOLTS; CISB
BTSTOBIBS; CBILDBBB: JDIPOSE TISSUE;
EBilS; KIBSBT3; IITEE; LOSGS;
flBCBBSS; BIIITH BaZtBDS; IBDOSTBIaL
ICCIOSSTSJ IBOPLtSHS
•ntopsy tissue. Represents 60f
recoTery. Calculated total body
atount ao aq
55 yr old votan »ho died of
Jancreatic carcinona 7 «o after
ndastrial accident in Seveso, Italy,
1976
111 exposed residents had burnlike
skin lesions, soae «ith chloracne
ITalT; IDOIBSCERTS; ADULTS; CI5E
alSIOBIBS: CBILDBBH; ADIPOSE TISSUE;
IRtIB; KIDBETS; LIVBB: 10BGS;
PlRCBEaS: HEALTH HAZARDS; IBEDSTBIU
ICCIDB^TS: BtOPLASnS
Autopsy tissue. Represents S9¥
recovery
?5 yr old voian «ho died of
pancreatic carcigoaa "> no after
iodoatrial accident in Seveso. Italy,
1S7«
ill exposed residents had bnrnlike
akin lesions, soae with chloracne
ITALT: ADOltSCERTS; ADULTS; CASE
HISTORIES: CBILDBEB; ADIPOSE TISSVE;
ESAU; tlOIBIS: LIVEB; LOBGS:
EJBCBSAS: BIIITH 8ATABDS; IBDOSTBIaL
aCCIDEBTS: BBOPLASBS
BErBBEBCB
Peagiani, 6.
1980
Journal ot Toxicology
and Environmental
Health «:27-«3


tleaolanl, 6.
1980
Journal of Toxicology
and Environmental
Health 6:27-43


Beggiani, G.
1980
Journal of Toxicology
and Environnental
Bealth S;27-a3


Beggiani, G.
1980
Journal of Toxicology
and Envlronoental
Health 6; 27-03


                                                                                                                                                                                            oo

-------
 Cit«tyliilB«  (8  CI|
 T-Htantaiat. a-tvtjl-  (9 CIJ
 111-92-2
CS-«19-«
II 129.2*. Bf -69 to -59 C. Sf  155-ISO C, TP 2 ma  Eg at 20 C
TISSUE
38*9
Imtt












EXPOSOIE MOTE













1IUTTIC1I
BKBOD
CO-SS












B0HBBB
or cisis
5* (387
aaaplea)












I1IBE
lot given












•Ell
0.218 ng/1
Geoaetric












GIIHII IfFOIBITIOI
•eanrei at 25 C and 760 mm eg
6.5» occicrcnco
loner aad apper oM-Sigaa Halts
0.043 »i 1.11 aaA

RaaltkT. 18-35 Tt oil, nonaaofclnq.
vctu blacks and Caucasians.
Chleaao, 11. Siqidlr controlled
cxperiMital conditions.
E1IITH: ILCOWtS; IILXIOIS; tDOlTS;
CILOIlnTCD ETDBOCtlaOHS; T011TIIS
cseanc concnDS; IULTB HITJEOS;
mtunci; aiTiEOLiSB; BITIBOLITES;
iCIOtUIOl IIPOSBtS; QBB» »BUS
B8FEEE1CB
Krotoszjnaki, B.I.
Bconeau, G.S.
O'Kill. B.J.
1979
Joarnal of inalytical
Toilcology Js 225-21*








          lM.  l-nittoso-  (« CI)
Ittbaaaila*. 1-MthTl-I-iiltresa- (9 CT]
C2-1S-9
CJ-B6-I2-0
•t 1«.1.  B» 152 C
IIS5V1
3900
Blood









iiposnBE BO or i











iiunicki
BRBOD
GC








t
1
B08B1B
OF C1SIS
a










IUGI
< 0.5-1.3 »9/al










Bill
Bot giTon










GEIIUL IirOSBlTIOB
tcfoce and after a«al iiqh in nitrate
aid aecoadari aaiaea. Bo siqii:icant
• ff«et of teal. 32 saaples.

17 and 30 yr old lapaacae.

Possible BitiMailna foraatiao in
lower SI tcact.
JI»1B; ID01TS; HOOD; OUTS;
raavtts; in«osiB»csi HIHEOLTTSS

BlfBBEICE {
1
1
Taaaaoto, B.
luada, T.
Taniiura, 1.
1980
rood and Coaaetica
Toilcoloqi 16:297-299





  to4«cau«
  112-M-3
  C12-826
  8B 170.3, B» -12 C, B? 216.2 C, TP  1 aa  Hg at  «7. 6  C
TISSUE
3*01
Breath










BXBOSOBE BOim











BXTBOD
sc-as










IOBBEB |
or CUES
5» (3(7










MICE
Bot given










SEAM
0.130 og/1










GEEIE1L IBFOIBKIOB
...
tenure! at 25 C and 760 la Hg
36.2* occurrence
to»«r ani npjer oae-siqaa Halts
0.03* and O.W1 »
-------
      EC0079 (Id poatlnqs i» CHElimj.
ITSStJ!
3902
Orise
EISOSOE1 BOItl
Ingest! on
IIUTTICU
BETHCD
Badiosetry
TOSSES
or cisss
«
B«GS
0.407-0.022!
I nilB
1
1
1
0.0161
cziiBii nroiRHiow
* excreted in urine daring 96 hr
after 50 iCi. Bost of dose excreted
III faces, blood negative.
EcaltliT volunteers, 22-39 jr old.
FCOI JDKTrTES; FOOD PBESBBTMIVES:
KT»BOIISI; JSIJtl: lEIZOfl
SEFIBISCE
Valsan, P-B.
Carter. D.E.
Prerson, B-i.
Ealladar, S.C.
1979
rood and Cosmetics
Toxicology 17:201-203
	 I
     000*78  (lo pcatinqs la CHUIIWI).
irssmr
3903
Urine






( txtosns soarz
Ingest ioa






	 1
HETHOD
Badiosetrj





t
t
IVXBSS
OF CASES
6







lltSI
0. 028-0. 06JT







JIEJII
0.0««







cittau, iirosHjTioi
1 excreted daring 56 hr after SO nci.
Bost of dose excreted in ieces, blood
negative.

fOOT IDBITITIS; POOD PBSSIRIJTITIS;
e(T»BOI,ISI!; OKIBB; 1EIEOH


MMZZWU
Ralsan, P.D.
Carter, O.E.
Brerson, B.t.
Balladar, S.C.

loot and Cosaetics
Torlcol'igy 17:201-203

   7S-1B-J
   C2-B*-C12
   «i S9.0. .T? -97.7 C, BP S7.3 C, T* 230 •> ffg at 2i C
1 TISSUE
1
1
1
1 390*
1 Breath












JIPOSORl FOTI!















I 19UTT1C1L
| BtTSCD

OC/IS












'
I 9tllBZE
I 07 C1SIS
1

8













| BIIGE
1
1

Hot applicable












I
1 IEK
t
1 trace aiout
|
1











1 GiitFiL riroauTror
1

CeiB»nd froi aikiova origin, la
ether details giT«n. Detected la
only 1 «61ect
Cryogenic saipllag teehnigne.

•ealttr illitarr and civilian
employees, O.S. lir force Scaool of
leroepiee ledicime, ages 23-«7 jr. 3
Eioken.
fllllttS; CBIOBIHTEC Bn»OC»BO>S;
C81OEH? OBGtUC COSPOOWDS;
CBLOioanzEics: FLTCBII: COBKUHDS;
EKHTI: IICCBOLS; T»1S; 1COITS

SErESSJCE

Conlclev J.P.
Caip. B.J.
•elch, B.E.
1975
Archives of
EBTiEoaaeittal BealtL
30 (2): 290-2 95






I
1 I-'
! S
i ^^














Ethane.  1,1-aichloro-2.2-bi9fp-clilarpaeirl)- (B CI)
Eenien,  l.l'-fZ.Z-dicltlocoethrlideaelbisia-chloco- (9 CI)
7Z-5«-«
CK-B10-CH
H 350.S6. BP 221-222 C
tISSOB
3 SOS
adipose


\
BIPOSDBE BOOT!





aUlTTICIL
HETflOD
OC




IO93EK
or CASES
60




111 1
I \ I I
\ \ \ \
I1IGI
< 0.10-1. 05 Fpa





SE1I
a. 27 pp»





|
t
\ » » It 1
* .-»- . _ i 11 i
eEIEllL MPOtUTIOI
Feriphenl kidwr ttt, rogtine
pathological exaalaatio»

«ge« 6 14-92 rr. S«liin«
BltBITTS; inTOPSlES; 19IPOSI *ISSHS;
noaccmm&im ; TBSTICHIB,SS BBB;
Kit ACT; DIlLmlB; S5TTIC91OB
tfOTTDl" BnftCHLOROEmm* LX10ME*
•EFE8EICE
Dejaxclciieere, ».
Steacbaat. 1.
Terstraetm, H.
Kips, «.H.
Toxioological European
eesearcb. 2 (2) -.93-98


CBic»t« o*»nc coBtovms' * i
i
l«M *«H 	 —

-------
mate, 1,1-diciloro-2,2-bi«(p-ctlorplienrl>- (« CD
ecBte», l.t'-K.Z-dlchloroetbrlia'eMlblAp-ckloro- fS CI)
7i-5«-»
C«-B10-C1»
El 350.46,  at 221-222 C
                                                                                     (COITTKJED)
nssvt
}»«
iniotic
flail
3907
float
3401
Blco-5.
«Una
3109
Blood,
aeraa
IPOSTOE coral




luimcn
BRHOD
OC-SC
SC-JC
GC
OC
IDIBEB
OF C1SSS
0
t 25
o> 15
CI 10
•1 139
b) 175
C) 199
d) 210
at 31 of
•1
b) 20 of
««
cl 10 of
19
at 35 of
50
a) 8 of 2
MICE
24 pp*
1 lot 4etectable-23 ppb
) lot o«tect»ble-35 ppb
) lot detectable- «32 ppb
a) 0-1.3 PFt
b) 0-H.S ppt
c) 0-5.0 ppb
d) 0-1.2 ppb
a) 0.5-2.1 ng/l
bl 2.5-23 09/1
c) 3.«-17 09/1
d) 3.1-318 ng/1
e) 3.5-11 as/1
Uil | SSIEE1L IJFOSB1TIOI I B!FEB!»CE
1 1
1 1
99 ppb 1 10 positive specimens I Saxena, B.C.
ontcic 1 1 Setl, 1.0.
1 Pregnant vonen, sinilar In f Hahajan, P.L.
1 tceioecononic lerel ml Sletarr 1 1910
1 tabits. »o occupational or 1 International Joaraal
1 4ccia*ntal eiposnre. Locknon, India 1 of E»riroua«ntal
1 1 Inalytlcal Chealstry
I risTicists; CBTORIHITSO BTDBOCIBBOHS; i 7: 2*5-251
1 CH10HI1! OSG1IIC COIMOTOS; COO; DDE: I
I tn; HDII: PRIGIUCT: IBIIOTIC i
1 MOID; ?llC!m |
i i
I i
1 6.9 » or - 7.9 ppb 1 a) Controls, Cull-ton pregnancies 1 saxeu, B.C.
! 15.2 » or - 12.5 | t) Fee-ten pregnancies 1 si.41i.gtii. I.E.J.
pb I cl Spontaneous abortions at less than | Setb, T.D.
c) 65.5 + or - 129.* 1 « »V I Krishna Rorti, C.5.
pb | | Bbargata. I.E.
1 H«alt»T. nan-exposad, pregnart mien, 1 Kntty, D.
1 ages 18-32 yr. U41*. | 1981
t 1 Journal of Inalytical
1 IlDIl; HOBTIOI; IDHT.TS; IITTIS; | Toiicologi 5:6-9
t E10CD; •HCBITl; COBPIBITHE 1
t 11U.H1TI01S; CBLOSI11TED 1
1 BIDBOCUBOIS; CBLOEII! OBG1IIC I
1 CCBPOTIOS; 1ISECHCIGBS; PISTIdDES: t
1 FISTIC1DI T.IS1BDES: MPUllTIC!! I
I ixcosa»; pBtenict i
i i
a) 0.1 ppb 1 a> Boral tlacks | Finilea, J.
b) 0.» ppb I t) ncfcu blacks I Priester. I.I.
c) 0.3 ppb 1 c) Qrban Caucasians | creason, J. P.
1) 0. 3 ppb 1 a) Boral Caucasians t Ha user, T.
1 I Pinners. T.
1 Ocbaa an! rnial cesltents of SC, I Banner, 6.1.
1 infants, children, adults, eiaerlr- 1 1972
I 1 lierlcan Journal of
1 SOOTH CUtOIIBk; 10VLIS; CHHCSE1; | Public Health
1 SICIU 5TODI1S; BIOO1 PUSH; | 62 (5) : 6*5-651
1 CCHftSITITE miOlTIOBS: ODD; ODE; |
1 ttT: DISIDBI); PESTICIDES; |
1 tCLTC9LOsn»ED BIPHEITLS; 115 1
1 tctiUTioi: fcoo coitiaimiioH; i
I P'StlCIlt ItSIDBES; P050LITI01! |
1 MtOSSBE; «VB1I 1HE15: OBBU IKllS |
1 1
1 1
a) 1.1 us/1 1 a) General popalation - continental I Kraithacker, B.
b) 6.4 ug/1 | central (rural) I llebic-Solbah, T.
c) 5.2 ng/1 | t) General population - island \ Kr«l1, n.
11 11 ug/1 | (coral) | Tkalceric, B.
e) 6.2 ng/1 I c) General population - continental | lei nee, I.
GeonetrLc aeau I contb (urban) | 1980
1 d) Stpoael ocrters - continental | International IrchiTes
1 north (urban) | of Occopational and
1 e) Exposed »crters - continental ( Environnental Health
1 icuth (urban) | 95:217-220
1 1
t General population, ages 6-79 yr. |
1 Occipationally exposed workers, ages \
1 20-62 rr. Tagoslavia. t
1 1
i TtJsesLirii: siooe stMH: CBIOSIHTED i
| gTOKOCiBBO'S: CEIOEIK! OPG1IIC |
1 CCBP01HS: DEE: DOE; DDT: PESTICIDES: |
I eiiicaLOECcYCLottmii: OCCOPITIOHI i
1 BI11BC3; FtSIICIDl HESIDUES; |
1 fC?0HTIOJ SirOSOBE; BOail UEHS; |
I mm issis i
1 1
(1EIT PiSE)
                                                                                                                                                                                           NJ

-------
Itaaa*, Ifl-dichloro^^-bisfn-cUorphwyl)- (8  CI)
Icrane, 1,1'-(2,2-dlcia.oroethTUa'en«)nls(*-chloro- (9 CI)
7Z-5«-S
CH-B10-C1*
IE 3SO.««, If 321-222 C
                                                                                      OS; ODD; 001; |
CBt! I»BI«: PBESIAICT: »H»IOTIC I
MOID; CtlCERl |
1
a| 25 a) lot detectable-* 1 ppb
b) 15 b) lot det«ctable-«2 ppb
c) 10 c) lot detectable-75 ppb
a) a.s * or - 8.3 ppl a| Controls, f all- 1 era pregnancies I Saxeu, B.C.
b) 10.7 * or - 10.7 b) Pre-ters preon ancles | siddiqai, a.K.J.
Ppb c) Spontaneoas abortions at less than I Seth, T.D.
c| 20-« « or - 22.8 9 «k (inclides fetas) | Krishna Barti. C.B.
PP* 1 EhargaTa, l.K.
Bealthr. non-exposed, pregnant w»ien, | ICnttj, O.
ages U-32 rr, India. | 1981
IIDI1; 1BOI1IOI: IODLTS; ?ITDS; [ Toiicology 5:«-9
EtocD: pticsiTi: cospiBiins i
ttlLOaTIOIS: CBI08II1TBO 1
ETseocitgois; caws IK osciaic i
CCBEOWDS: IISICTTCIDSS: PESTICIOBS; |
FISTIC ID I SISXDOZS; POPB1.1TIOS I
IlPOSmS; 7BESI1ICT |
1


M
N5
to

-------
 !tku«.  t.f.l-trlcaloro-
 71-SJ-6
C2-BJ-C13
n 133.»2. « -3fl.«1 c, BP 7*.1 c. TP too » 89 at 20  c
1ISSOI

341*
Bteatk










391S
Breath












siMsnn BOOIE



























i in men
IBTBOD
ac/is











QC'IS













nun
Of C1SIS
8











» (387
saiples)












IMGE

lot detected-1«0.0 ««/kr











lot giren













Bill

20.1 «g/nr











1.8 na/1
MOM trie












6Sl*tal tlFOBBlTIOB

Cciponad related to nornal
•etabolita. *o other details glren
Cryogenic gaipllag technique.

SealthT illltarr and civilian
employees, U.S. air Force School of
lerospace Dadlclae. aq«s 23-47 yr. 3
>*oter3.
tiizms; cnotiiniD iiosoctssoss;
CELOBIW oisinc coiMmas;
CILOBOKIZIIK: HVOSIR COH001DS:
IttKI; IICOBOLS; TEHS; IB HITS
Masaccd at 25 c and 780 •• Bq
21.7* oeenrteBce
Lo««c a«d ipper oae-Sigaa lilits 0. *2
aid 7.7 an/1

Bcaltkr. 18-3S TC old. aonsaokiaj.
ottaa blacks aid Caucasians.
Cfcicaqo. IL. llqldlT eoDtiollel
cipcrlmtal coaditiom.
HiiTB; IICOEOIS: iiLisois; units:
CHIOHHTID ITDBOClSBOIS; 7O11TH.I
CB61IIC CC8PCOIDS; SE11TH I1U8DS;
IlHlllTIOl: IR1BOIIS1: HET1BOLIT8S;
ccrmiTioi nposiii; eaTl)-2-(p-cUocoph«arl|- (8 CI)
 Kaxeae. 1-cUoro-2-(2.2,2-trichloro-1-(«-cilocopbenil|«tliTl)- (9 «l
 7t»-02-«
 C1*-B9-C15
 81  3S«.»9, EC 7«-7«.«> C  (coc)
                                                                                                                                                                                              to
                                                                                                                                                                                              U)
1ISSJB

3916
tlDlotlc
flail






3917
(load.
plasaa













EXMSin BOOTI


























1MLTIIC1L
RZTBOD
SC-BC








ec















miiBzs
or CUBS
so








a) 139
b) 175
c) 199
d) 210












BUGS

0.5-11 ppb








a) 0-2.7 ppb
b) 0-3.9 ppb
c) 0-2.7 ppt
d) 0-1.6 ppb












am

1.06 ppb
SeoMtric







a) 0.2 ppb
b) 0.* ppb
c) 0.2 ppb
1) 0.1 ppb












Gzmii iirosBiiioi

15 posltiTe «p«ciaens

tlegaaat voaca, siillai in
habits. Ho occnpational or
accileatal erposare. Locknoi. India
ftSnciDIS; CHLOBI1ITSD HIDBOCABBOIS;
CEIOBIIS OB61HC COBP001IDS; DID; DDE;
BtT; IIBI»: ciEeiiicT: IBSIOIIC
IIOID; PLicirri
at Snral blacks
t) Urban blacks
c) nrbra Caucasians
i) Bvral Caucasians

Urban and raral residents of sc.
infants, ckildrea. adults, elderly.

SOOTH CHClIll; 1B8LTS: CHILCTEB;
BICIJT. STUDIES: BtOOT) PLaSRl;
CCIPtDtTIfZ miOMIOIS; DDD; ODB;
Ctl; OTEIBBIB: PISTICISBS;
EOIICBtOBIHTTO BIPBfBILSi tl<<
EC11QTIOI: FOOD COIT»«H»TIOI:
PISTICI9I BESIDDIS; POPOL1TIOR
upasnB!: BOBIL isiasj OBBII nias
BEFEBEBCB

Sanaa. B.C.
Seth, T.D.
Hahalan. P.L.
1980
Internatiooal Joinal
of ^nrironnental
tnalrtical Cheaistry
7:2*5-251



Finklea, J.
Priester. L.E.
Creason, J.P.
Baaser* T.
Binners. T.
Eaaaer. D.I.
1972
taerlcan Journal of
Public Health
C2(5):6«S-6S1






(HIT P1S£)

-------
 Ithane, 1.1,1-trickloro-2-(o-chloropkeayl)-2-(p-ckloropli«Byl)- (8 CI)
 EeBxene, 1-chloro-2-(2.2.2-tricliloro-1-(»-chloropb«ayl)ethylj- (9 CI)
 789-02-*
 C1»-B9-C15
 81 35*.«9. BE 7«-7».S C (cor)
                                                                                       (CORIMIEO)
IISSVE

3918
Placenta









Exposure sotrtE











1BALRICAL
BETHOD
OC-BC









IOSBEB
OF CASES
SO









B1BGE

9-63 ppb









BE* I

«9.63 ppb
Geoaetric









GZIE1AL IIFORBaTXOB

20 positive speciMIS
Pregnant voneB, siBilar in
socioecoaoslc level and dietary
habits. Bo occapatiomal or
accideital exposure, tncknov, India

MSTICT9I5; CBLOBIBATBD HTDBCCABBOIS;
CELOBiit OIGABTC COBPOOBDS; COD; DOE;
CCT; nni»: PBSGBAICT: ABBIOXTC
flUID; PLACIITA
EErtiBBci

Saxena, B.C.
Seth, T.D.
Bahamas* P.I.
1910
iBtecaational Journal
of EnviroBaental
Analytical Chenistry
7:2*5-251



tthane, 1.1. 1-tricliloro-2,2-bis (p-chloropfceofl)-  (8 CI)
tcnsm. 1.l'-(2.2,2-trlchloroetfcrlWeB«)bi»(»-ctloro-  (9 CI)
58-29-3
CH-B9-C15
BI 3?*.59.  it 108.5-109 C. BP 260 C, TP 1.5X10(1-7) •• Eg at 20 C
1 TISSUE
1
1
1
1 3919
1 Adipose
1
1
1
1
1
1
3920
Adipose
3921
Adipose
EIPOSDIS BOOTS IIALYTICAL B9BBSB
BETHOO Ot CIS!



1
1
1
1
f
1
GC

1
60
7
BABGB

.20-3.70 ppl
t given
MEAI GBIZBAL IBPOBBATIOB f BEPEBEBCB
1
,._,.. 	 1
1
1
1. 52 ppn
1.4 * or - 1.26 ppn
1
B«vie* | Delchnann. I.B.
1 tlacDonald. I.E.
Exposed persons in the United states, I 1977
tfce setherlands, Sweden, Israel, I Ecotoxicology and
lapan, USSB, Poland, Seraany, India, I Environnental Safety
Bulgaria, Pakistan, Anstria. I 1:89-110
1
feporteJ cases of hypertension, I
CEGs, or ispairsent of neacosnscalar I
function after acute exposure to I
1 continatlons of pesticides, tat most |
1 data show no adverse effects after I
1 long-tors occupational exposure. I
JCSTBIl: BBIGARIA; GE8IA«r: IRDIA; 1
ISBAEL; JAPAI; BETHIBll-fBS: PAKISTAB; 1
tciiiD: BussiA; CTEDMI IBITED t
STATSS: ADIFCS! RSSffE: BLOOt; BLOOD I
PUSSA: BtOCC SEIOfl: !BrTBBOCr*!S; |
KOICOCTTES: BILKj It lit; SETIE8: |
BIALTB fAZADCS; OCCOPATIOBAl HAZARDS; |
PCPOLITIOK HPOS08E; XEOPLASBS; I
FISTICI9CS; CBI08IVE OSGAXIC I
CCIPOtr»DS |
1
Periok«ral kidney fat. routine ( De-jonckbeere, W.
Fatbologlca 1 examinations | stenrbant, I.
1 Terstraeten, E.
Ages 6 so— 92 yr. Belgian I Kips, S.B.
1 1978
!E1«IVS; AUTOPSIES: ADIPOSE TISSUE; 1 Toxico logical European
EIOACCISBLAtlOB; PESTICIDES; DDD; 1 Research 2 (2): 93-98
let; DDT; DiiiDaii: BSPTACHLOS i
ITOIIDf; BEXICnoBOBEBZEIE: 1IBDABE; I
CnOBIIB OEGAIIC COBPOHBDS |
Bospital patients | Inoae, T.
1 Abe, S.
Japan | Takanatsu, 8.
1 Aoki, «.
tOtT.CBLO^I«ATBO IIPBMTLS; DPP; I "liki, S.
BIXACBtOBOCTtClOBEIABE: BLOOD PUSBA; ) Fnlluara, K.
I'OPLASflS; JAP11; CAStBOIBTESTlnL | 1975
STSTW1; PESTICIDES: ADIPOSE TISSITS; I Tnknoki Helical Journal
1
                                                                                                                                                                                           to

-------
 ma»e.  l.1.1-triehloro-2,2-l:is(p-cliloropIi«»yl)- <* ci|
 e«a»l»r  1. f'-(Z.2f2-tricMoro«thrU*«»)l>i«t»-chloro- (9 CI)
 Sfl-29-3
C1«-«9-C15
fl« 35«.50, HF 106.5-199 C. » 2«0 C, TP  I.SXIOfI-7}  u Bg at 20 C
IISSBI 1
3922
1 1
1 1
| |
3923 1
Blood |
1
1
392*
Blood

!IM50ra lOBII
<



SFTHCD
SC-BC

SC-EC

in Bit
or cis is
l) 22
b| 1*
4 6
1) 6
» 6

a) 25
b) 15
O 10

	 iiiei i Bill BMIUI nroMinoi'" i IEFBBIJCB
! i
lot gives 1 a) 2.60 + or - 1.33 al Elderly >«• 1 BreTik. E.H.
lot gives 1 sg/kg ») Elderly «csen 1 Bjerk. J.B.
lot givsB 1 bl 1.86 + or - 1.»1 el Toang sen I 197>
lot givee 1 sg/kg «1 T.on»g >oa«a 1 Icta Pharmacologies at
lot gives 1 c) 0.95 * or - 0.26 e) levbocBs 1 Toxicologies
1 ,,/kg Perirenal tissue |»3(1):5>-«3
1 d) 0.91 * or - 0.61 197C survey. Significantly higher in I
I ag/kg elderly, particular IT in sen (P < I
I e) 0.75 * or - 0.56 0.051. Significantly lower levels in I
j i
-------
I thane. 1.1,1-triehloro-2.2-bi*(B-caloroph«Tl)- (8 CI)
Bentene. 1.1>-(2,2.2-trichloroethrlld*M)bls(*-ehloro- (9 CI)
•0-29-3
CW-B9-C1S
81 35«.50. BP 108.5-109 C, BP 260 C. TV 1.5110(1-7)  » Bg at 20 C
                                                                                     (COITIIOSD)

























1ISSIE


392S
Blood.
Flan*










392C
Blood,
plasaa















3927
Blood,
1 serai
1
1
1
1
1
1
BXKSOIS BOOTE

















111LTTICU
BETBOB














ec

1
t
|
I

1
I
1
1
1
1





1 ec
I
IUBBEB suet
or CASES

a) 27 a) Jot given
b) 16 b) lot given
c) 37 c) lot given










a| 139
b| 175
c) 199
d) 210














32 of
1
< I b) 8 Of 19
1 C) 17 of
1 ««
1 d) 32 of



1
1
1
1
1
1







SO
e) 7 of 28

















a) 0.6-28.2 ppb
b) 0.1-62.7 ppb
c) 0.1-6.6 ppb
d) 0-6.0 ppb



BE1I


a) 3.5 « or - 2.50
ppb
b) 4.7 * or - 5.53
ppb
c) 3.0 « or - 1.96
ppb







a) 8.8 ppb
b) 5.* ppb
c) 1.7 ppb
d) 1.6 ppb


entail itrosaiTioi i BEFESEICE
I
i
a) Hospital patients | Inoue, T.
t) Zsaciated persons j Ibe, S.
c) Ron-esaclated persons 1 takanatau, B.
1 »oki, ».
Japan I Biki, S.
1 rajivara. K.
lOITCBLOBIIITB) SIPBEITLS; DM; I 1975
BEIICBtOBOCTCLOBRlIE; BIOOD P11SB1: I Tnknoka Redical Journal
IIOPUSIS; JIPIB; G1STIOIITESTIML I 66(10:610-616
SISTW: PESTICIDES; IBIPOSf TISSUE; I
IITEB; KigitTS; 01EITUB |
1
1
a) (nral blacks I Flnklea. J.
r) Urban blacks | Priester, I.E.
e) Urban cancasians I (Treason, J.p.
4) Baral eaacasiais I Banser, T.
1 Binners. T.
Orban and rural residents of SC. 1 Banner. D.I.
infants, children, ad«lts, eldorlr- 1 1972
1 Aaerican Journal of
SOUTH ciaotm: IDOITS; CHILESEI; i Public Health
B1CI1L STODIES; BLOOD PUSH; | 62 (5) : 645-651
CeiPlBITTTI tYllDHIOBS: DDK: DIE; I
ttr: tnunii; PESTICIDES; i
EOITCBLOHIITID BIPBEBTLS; AIB I
| (CIITTIOB; FOOD COETMIBlTIOIi |
| PISIICID! RESIDUES: POPVL1TIOB I
| EIPOSUB!; BOMl UB1S; BUSH M»5 |
1
1
a) 1.1-5.3 ng/l a) 2.2 ag/1 a) General population - continental I Krauthacker, B.
b) 3.7-17 ng/1 b) 6.1 «g/l central (rural) 1 llebic-Xolbah, 1.
e) 3.1-39 og/1 c) 7.2 ug/1 r) Senacal popalation - continental I Krai-), B.
) 3.7-96 «g/l | d) 15 og/1 a««th (arban) | TkalceTic, B.
) 4.7-29 og/1 | e) 11 ng/1 e) General population - island 1 tteiner, EJ
1 Seonetric >eans (rural) | 1980
1 d) Exposed workers - continental I International IrcniTes
( north (urban) | of Occupational and
1 e) Ixnosed corkers - continental I Environeental Health
tenth (urban) I 05:217-220
1
Gmecal population, ages 6-79 rr. 1
Occapationally exposed workers, ages |
20-62 rr. Tngoslaria. 1
1
TOSCSHTIl; EIOOE SB1!IH: CELOEIIITES I
RTBtOClSIOIS: CBIOEI1! OBGIHIC |
ccnoowos: Dtt: DDE: ODT; i
ifitcRtoiccTcioBixm: PESTICIDES; i
CCCnPATIOIlI B13IIDS; PESTICIDE |
BISIDQES; POPO11TIOI SIPOS01Z; BBB»L |
IB IIS; ISBll UEtS |
(HIT PISS)
                                                                                                                                                                                        N3

-------
       ,  f.f,1-trical,oro-2,2-bis(p-ekloropa«Tl)- IS CI)
ttmutt,  1,1*-(2,2,2-trichloro»thrlU*a»)i>LsH-chJaro- (9 CI)
SO-29-3
CM-B9-C15
II 354.50, H 10«.5-109 C. 31 260 C, TP 1.5X10(1-7) mm  Bg at 20 C
                                                                                      (COITIIIBD)
IISSBE

3928
Blood.
senm























3929
Bilk










3930
Bilk





3931
Bilk












tlPOSOlE ROOTZ


























































i uimcit
MBTBOD1

























-
BO-EC

















GC-IC












BOHBSH
p cists


























10










25






a) 1»
b) 11
c) 10
d) 9












URGE



























8.0-135.4 no/kg










lot given






a) lot given
l) lot given
c) Rot given
d) Hot given












BEll | GHIUL IBPOBBlTIOl

1 leviav
1
I Zxposed perscaa ia the United states.
I tie letkerlands, Svedem, Israel,
I Japan, nssi, Poland, Gernany, India,
| Bulgaria, Pakistan, avstrie.
1
I teportea easts of kypertension.
1 elevated seen cholesterol, abnormal
1 IT.GS. or iapairaeat of nenronscalar
I fmction attar acute ezposare to
I conbinations of pesticides, bat cost
1 data shov no adverse effects after
1 long-ten occupational exposure.
1
1 ItSTBIa; BOieiBII; GEBBliy; mil;
1 ISBlEl; JlPtl; IZTEBBLllOS; PMCISTal;
1 iClalD; BOSSU; StEDEB; UBITZD
1 ST1TIS; 1DIPOSE TISSUE: BLOOD: BLOOD
1 PUSH; B100B SBBVB; IBTTBBOCTTZS;
I lIOKOCTtZS; HLK; OBI1B; BE»IE«;
I IIUTB HIZIIES: OCCOPITIOIIL BIMBOS;
1 PCPD11TIOI ZXPOSDIE: IIOPLlSBS;
1 PISTICIDIS; CRLOBI1E OBS11IC
1 CHPOOROS
1
1
50.8 og/kg I lactatlng sotbers
1
1 17-«1 yc olds froa Slavonia Province.
1 Jugoslavia.
1
1 TOGOSLlVIi: IICTITIOR: SILI;
1 EI01CCHBDUTIOB: BOBat 1BE1S;
1 CBIOIIHTID BIDBOC1BBO1S; CBLOBI1E
| OBGaBIC COBPCH10S; CBLOBOBI1ZE1IS:
I It I; DOT; BtllCBIOBQCTCLOHIIUE:
I EISTT.CIDSS
1
180 * or - 1*0 ppb | lilk bank donors
I
1 California
1
1 cuifOMii: UNITS: IRLK;
1 IIOlCcniBllTIOl; LlCTaTIOl; DDE; DDT;
1 PISTICIDZS
1
1
a) 50 + or - 38 ag/kg 1 i) Csla. large indastrialized city
b) «9 » or - 31 eg/kg | r) Bergen, large iadastrialized city
c) 39 » or - 17 ugykq 1 c) Barstad, saaller city vita large
d) 29 * or - 13 ng/kg I chenical/petrocaeiical complex
1 d) Porsgrvna, non-industrialized
1 fisting eonsanity
1 197* nrvey. Significant decrease at
1 all sanpling locations conpared to a
1 1*69/70 sarvay.
1 lotwgiaa anthers, ages 25-28 yc.
1
I ItlPOSZ TISSUE; IILK; COBPiSlTIVB
1 tvllolTIORS; K)B«1T: lOOLTS;
I IDTOPSISS; inBOBl; DDT: CB1CBII1TED
1 BTBEOCIBBOIS: DDT: PESTICIDES:
1 ECITCB108H1TID BIPBEITLS
1
flIXT PlGZ)
IEPB1E1CE

eichiann, V.B.
acDooald. I.E.
977
cotozicology and
Environmental Safety
:89-110




















Kodrie-Snit. B.
Slit, Z.
Olie. K.
1980
Pesticides Bonitoring
Journal 1«{1):1-2






narrod, J.E.
asgnith, B.T.
1980
lev England Journal of

303(16) :9«5-9*6

Brevik. E.B.
E-lerk, J.E.
1978
teta Pharmacologica et
Toxicologica
«3(1)s59-63












                                                                                                                                                                                              t-0

-------
Ittane, 1.1,1-trichloro-2,2-fcistp-cBlorapnenrl)- (8 CI)
Ecnxem, 1. tI-t2,2,2-trichloroethylid«i>e) fcistl-clOoro-  (9 d)

C11-B9-C15
IB 351.50. IE 108.5-109 C, BP 260 C, »P 1.5110(5-7) •• Hj at 20 C

tissos
3932
Ri Ik
3933
Silk, fat
1 393*
1 Placenta
f
1
3935
Dtine
»
UPOSHEI BOOT!
Ineestion
1
1

V -
inimcii
BET BOD
BC
OC-BC
1
i ec-Bc
1
» *
tmtSt
07 C*S
a) 21
b| 2«
C| «5
d) 15

a) 25
b) 15
C) 10

BUGS | SIl* 1 GEIIBJL IIFOBI1TIOI I KKBMCS
1 1 1
II 1
1 1 1
a) 0.045-33.122 ppa I a) *.223 ppi | »l faral lotters, fat basis | POIO Lora, H.
b} 0-10.361 ppi I b) 2.745 ppa | b) Orban aethers, fat basis I Berrera Racteache. 1.
•e) 0-13. 122 ppa 1 e) 3.««1 pp» | c| 111 letters, fat basis I Polo rillar, l.S.
fl) Tot gi»«B f S} 0.06S ppa I 4) 111 lotlieia, (hole ail* basil | Lopez-Gineaai, H.
t | Data for sei of all pesticides and | Jodral Tillarejo, B.
I | cciparismB «ith Talus of other | Iglealaa Perez. J.
1 I investigators qiven | 1979
1 1 I Fevista Ispaoola la
1 I Bursinii aethers fro* Cordoba region, I pediatria
I | Spain f 35(206) :93-1 10
1 1 1
I i spin; IDOLIS: aziK; cmoBiii osunc i
i i ccepooiDS: pEsnciots; IGBICHLTD»E: i
| | SIBIL IBUS; DBB1I 1BE15 |
t t i
a) Hot ot gifen | ppi | f) 1977, 20 saiplas I Hanita, If.
1 d) 0.1* » or - O.tS 1 | 1979
1 ppa | 100-1*1 lactating «oaan, 2 acaths | International archirea
1 e) 0.49 » or - 0.18 I aft*c dallrecr- lesideats of Osaka 1 of Occupational and
1 ppa | Ir*f«ct*re, Japan, varied diets aad 1 £B*lrona«atal Bealtb
1 C) 0.29 » or - 0.09 | e»iroa*eatal conditions. I 13:1-15
1 PPi 1 {
I i iisTicmts: SOT: OBGMIC CHLCBHE i
I | COIPOVIDS: JIM*: tDHlTS; UCTaHOI; |
I i (us; iioiccoauLtTio*: i
i i FciTcnoimiiD iipaariLS i
i i
lot detectable- 1 • ppb
Rot detectable-55 ppb
Rot detectable-210 ppb

1 1
at «. 1 » or - 3.9 ppb 1 a) Controls, fall-ten pregnancies i Sazeaa, g.c.
b) 19. S * or - 14.9 | t) Pre-tere pregnancies | slddiqni, H.H.J.
PPb 1 c) Spontaneous abortions at less than I Seth, T.D.
ct 57.2 « or - 71.8 | « »lt (iaelades fetss) | rtishna Sarti, C.S.
PPb | t Eharga»a, I.E.
1 BealtnT. non-ecposed, pregnant vonen, | KnttT> D.
1 age 1*-32 ji, India. ) I9B1
1 | Journal of inaljtical
| HDI1: 1BO»TIO»: iDBLTS; FlIOS; I TorlcologT 5:6-»
1 EICCD: Pticsni: COBPIBJTITE i
I iTitaiTions ; cnosiiaTis i
1 BltSOClSBOIS; CBLO8IR OfiGMIC I
1 CCSMHI3S: IISECTICIDBS; PISHCIDKS; 1
1 PISTICI3I SZS1BMS; POPtTHTIOf 1
t 'IPOSBRI; PI1GMKT |
....._ 1 1
) leviei | Delchiana, U.S.
1 I EaeDonald, 9.5.
I Ciposed perscus in the united states, I 1977
1 the Vetherlatds. Svedea. Israel, I Zcotoxicology aad
1 Japan, 7SS?, Poland, Gertany. India, 1 Zniitonaiental Safety
1 Eolgaria. Pakistan, Instrla. 1 1:89-110
1 1
I Beported cases of hrpertensicn. |
I elentel cer» cholesterol, abnorial |
I lC€s, or iapalraeDt of nearcaascalar 1
1 function after acate exposvce to |
1 coiblnatiois of pesticides, bat cost I
1 data show nc adverse effects after |
t lon^-teri occupational eiposnre. |
1 I
I nsni*: BDIGUII: GIEBUI; noit; i
| 15BIB1: JIPII; IRHE1LH1IS: PKISTtl; I
I ICIIDOT SDSSIl; SH5DII; DIII1D |
| S11TIS; 1DIPCSI IISSUS; B1OOE: B100D |
| PlaS<»; B10CS SUDHi SBTTBEOCTTBS; |
| ItOKOCTTJS; BIlKi B81IE; BBflHi |
I B1U1R IIZUIS: OCCVPtTIOIll HaZlSBS; |
\ IOI1HTTC1 EIPOS01I: IZOIlaSHS; |
| ftSTTCT«lS; CffLO»I*I OBOHTC \
\ CC1VOUIQS |
1 1
                                                                                                                                                                                        N3
                                                                                                                                                                                        c»

-------
It It**,  1,1.1-trlcfcl<>rQ-2.2,2-trlflaoro-
3f«-?8-S
cz-ci3-M
(f 187.38, Bf 1«.2 C, n »5.« C
TISSUE
3936
lr«ath










ElIOSOBB EOOI I












IBlimcAl
arm CD
ec/«s











IORBER
or cis is
8











EIBGS
lot detect «d-580.0 ng/hr
"










mi
88.3 «g/hr











GEItlAI. IirOBBATIO*
Pntiois eiposare to conponad. lo
ether details gives
Cryogenic saiplinq technique.

lealthv lilitacy ana civilian
employees, O.S. air lore* School of
Aerospace BediciM. ages 23-»7 yr. 3
iiokers.
tllZEBES: CBtORMATII BYDBOCABBOHS;
cnoBii? otcinc coieonos;
CBioBomznis: twonn COBPOOIBS:
tsuiH: iiccBots; TE»S: iiniis
BEfSIEBCE
Conkle, J.P.
Caip. B.J.
Mich, B.I.
1»T5
lICklTQB Of
Imlronaental Bealth
30(21:290-295





IthtM, 1.2-dichloro-
107-06-2
C2-B1-C12
(I 98.98. BP -35.36 C. BP 83.5 C. TP  100  ••  Ho.  at  29.4 C
IISSO!
3937
Ircath










IIPOSQtS SOUI1 |
1
1












1ULTTICU.
BRBOD
6C/BS











KDBBIB
or cists
8











ItlGB
Bot 4at«ct«d-0. SO ng/hr











Bill
0.10 ag/kc











SEItitl IBfOBBHIOB
Coipomi froi ankaovB origin. lo
ctfc«r details qiven
Crroqenle saiplinq techaiqae.

Bealthr lilitacr and civilian
eiplorees, V.S. lir force School of
lerospaec Dcdieliie, ages 23-07 jr. '3
linkers.
EtKtRSS; CBIOBIIITZE BTDBOCABBOHS ;
cnosm oBsinc COBPOVIDS;
CB1QBO!BB7IIIS; FID C8 I IB COBEOUBDS;
MllIH; HCOBOtS; THIS; »BOITS
BE rial JOB
Conkle, J.P.
Caap, B.J.
Belch, B.I.
1975
archives of
EnTiroBMntal Health
30(2);290-295





                                                                                                                                                                                             K)
                                                                                                                                                                                             VO
 Ithanol. 2.2,2-trichloro-
 115-20-9
 C5-B3-C13-0
 ft 1»9.«2, BI 18 C, B? 151-153  C
•ussot
3938
Blood


EIPOSOB! SO01E
Inhalation
•

UUCTTCll
RETBOD
GC


BDHEEB
or CASES
5
-

S1IGZ |
1
_,
a) 0-2.8 ng/al
b) 0-1.* ug/»l
- 	 - -
(HE IT
9E1B 1
a) Bot given
b) Rot given

PJGI)
6ZBCB11 I1FOSBITIOI
a) 10 hr and day 5 of SO ppi
tcichlocoethvlene, 6 hr/daj, on 5
conaecative days
t) 10 hr and day S of SO
tcichloroethvlene, 6 hr/day on 5
consecative dars plas ethanol
pcetceatcent. Ethanol given to
•aintain blood level of 0.06*.
20-26 vr old students. »t 62-77 kg.
CBIOSIBJTID BTB8OC»BBO!IS; 1LCOHOUC
ItVntASES; BIOOD; BLOOD PL1SB1;
OIIIE; HETIB01ITES: DEMBOIISJI:
1 CULTS; GTIBAtT

EEfEBSBCE
Buller, G.
Spassonski, B.
Benschler, D.
1»75
Archives of Toxicology
33:173-18»
1


-------
     Itbanol,  2,2,2-trlcUoro-
     11S-20-8
     CS-B3-C13-O
     ft 149.12, » It C. EP 151-153 C
                                                                                           (COITUOED)
IISSOI
3935
Urine















Eivosns BOOM
Inhalation
















1U1TTICH.
BETH CD
6C
















IOEBSB
OF C1S3B
S
















B1ISE
a) 160-35 19
i) 120-10 •?















mi
a) lot giren a) Rat
9iren















Giimi iiroifliTios
a) Day 5 and 6 of SO ppa
tricliloroetfcTlsne. 6 hi/day, 5
consecutive days. Initial value. 102
•9 *n day 1
ttieiloreetnyleita. 6 ar/day, 5
ccase«ti*« taya plas ethaiol
Tt«tr«ata«nt. Initial valv«, 70 ug on
ttl 1
2* ar etcretloas. Itaaaol glren to
•ajatalt blocd !«»«! of 0.0«%.
latiaatea fcoa grapi.
JO-26 yt 014 stqdoata, lit «J-77 kg.
CELORX1HED HIOROCIBBOSS: 1LCOBOLIC
I1T1»»SIS; IIOOD: BLOOD PLlSOi;
mil; arriBOLiTES; HBTISOLISH;
i coirs : sEtauy
i
ssnetici
Bailee. 6.
Spassovski, B.
B«nschl*rr D.
197S
Jlrcbives of To xl colour
33:173-18»












   Rtciw. dicalorodlfloaro-
   i71«-03-2
   «« 133
TISSUE

3940
Br«ath







1
1

i
1 ElfOSOBB BOgiB














1 1IURJC1L
I BETIOO
1

GC/IS












VDflBSS
or cisss

8

f










I B1IGE
1
f
lot tat«cted-0.029 og/ir











'
BE19

0.009 ag/lr












t GEIIiil IKFOIRaTIOI

FreTioos czpasnre to coipoimd. Ho
cttor datailc qi»«n
Ciyogeaic saapliag technigae.

acalthy ailitary aad ci»ili«o
•aploye«sr 1?.S. lir FOTC« School of
lerospace Hedicin«v ages 23-47 yc. 3
saokecs.
CIIZEVIS; CHlCSHlTtt BTOIOClBBOlS;
CKOBTKB oseinc coipotmos;
catCHoetmns: PLHORISE COIPOETIDS;
fBHTB; 1ICOBOLS; TlliS; iBOlTS
1
BEPE1EIC!

Conkle, J.P.
Caap» B.J«
»elch, 3.1.
1975
ArcbiTM of
EavironBental Health
30(21:290-295






                                                                                                                                                                                               CO
                                                                                                                                                                                               o
Itljl aleohcl  (8  CI)
Itaanol  (9 CI]

C2-B6-0
It 16.07. U -117.3 C, BP 78.32 C,  tp HO an Bg at 19 C
IISSOI
39*1
Blood








t
EIPOSIBS BOOTI
Inhalation










IIIITTICII
iZTICB
GC










•OJIBIH
OF CISSS
6









1
BIIG3
a) 0. 039-0. 06«
b) 0.0»3-0. 073S









9X11
a) 0.0541
bl 0.059^









GEitui irroasiTicu
..
a) la trichlcioethylene treatieit
b) 100 ppa trichlorOBthyleoe
Sange amd icaa for 6 \t period

20-26 yc old students, vt 62-77 kg.

CILOEIlkTID BIDBOCIBBOSS; AlCOHOLIC
HflBlSIS; BIOOD; BICOO PllSSl:
DBIBEl II'TJBCIITES; 15T»BOIISn;
icnirs; GIB tin

IBFEBZICE
Bailee, G.
Spassovski, R.
Peosciler, D.
19.75
iTcbiTes of Toxicology
33:173-189





                                                                                        (1111  PaSl)

-------
      alcohol  (8 CI)
ttiaaol  (» CI)
CJ-B6-O
» ««. 07, BP -117.3 C, BP 78.32 C.  TF «fl •• tg at 1) C
ttSSVt

3M2
Breath




3M3
Heath










39M
Breath












nposm SO«M

































1I1XRIC1I
BET BOB
ec/as





SC/IS











SC-15













BffBEJB
or cisxs






6











5* (38T
saeples)












I1IGX

0.05-0.36 ppe





lot oetected-MO.O «g/ar











lot ai»«













nil

0.13 ppa





136.1 no/he











9.* ««/!
GCOMtClC












eiHui nrosniTioi

Corrected for level is inhaled air

tcaltir adllt*

sunn: HQHS: BHSITEIBT«I IRBOVS;
fiinioL
Coipani rtlatei to normal
eetahollai. lo otter details girea
Crrogenic Baiplla? technlqve.

Bealtkr "Hilary u« elTlliaa
caployees, U.S. ail force School of
Krespace s«dieia«, aqea 23-*T Tr. 3
giotori.
iiizms; cnoBimit ITDBOCHBOIS :
CBIOUMI oistric CPHPOTIIDS:
cnioBomznzs: n.0otm COBPOOIDS;
isiiTS: iicoiois: tnas; IDOLTS
Kanrei at 25 C aid 760 >a B?

-------
  Ithyleae (8 CI)
  Itnene (9 CI)
  74-85-1
  C5-B4
  HI  28.05 C. IP -169.» C.  BP -103.9 C. TP 100 •• Bg at  131.8  C
TISSOB
3946
Breath










EIPOSDSS BOOT!












ininiciL
BSTBOD
GC/BS











BOB BIS
or CISBS
8











BMGB
let detected- 120.0 ng/hr











BZ1B
1S.1 «g/hr











GEIZUL IIFOR81TIOI
Ccsponad related to noraal
Htabollsi. le other details given
Cryogenic sampling teehnigie.

lealthy illitarr aid ciriliaa
employees, O.S. lir force School of
lerospace Bedieiae, ages 23-47 jr. 3
ciokets.
tiixnts ; CBIOBIBHBD ITOBOCISBOVS;
CBIOBIK OBGIHC coiPooiDS:
CBioaoBE«u»is: FIOOBUE COBFOOIDS:
iiiiTB; iiccEois: TBIIS; IDOITS
BErXBEICB
Conkle, J.P.
Ca»p, B.J.
Velek, B.B.
1975
•rchires of
BoTiroBMatal Health
30 (2): 290-295





fthylene, chloro-  (8 CI)
!th««, ebloro-  (9 CI)
7J-01-*
C2-B3-C1
BB 62.50,  BP -13.« C, TP 2600 •• at 25 C
I IISSOS
1
1
1
1 39»7
Breatk





XtPOSDBB BOOTI I 1ULTTIC1L BDHBS
I BBTBCD OP C1SIS
1
1
Inkalation 1 GC 5
t
1


1
1
IIB6B



a) lot giren
h) Bot gl«n
c) Bot givea
d) Bot gi»«»
e) Bot giT«n
f) Bot given

1
1
1
1
1 1
1
I 3948
1 Ereath










1
1
1 6C/ES

\























g












ug/kr










IStl



a) 27.6 eg/en •
b) 11.2 »g/cu a
c) 5. 8 ag/cu e
d( 2. 8» «g/co a
e) 1.30 •g/Cd a
f) 0. 5» ag/ca a







0.09 tigXhr











GBIZB11 I»FO»»»TIOI



a) IieeJlatcly after $0.0 ig/co •
fc) leieaiately after 30.0 ag/ca •
e) lemediately after 15.0 ag/ca •
1) 30 lin after 60.0 ag/ce e
e) 30 ala after 30.0 ag/cn e
f) 30 iln after 15.0 ag/ca •
6 hr ezposare

Bealthr 26-31 ji olds, Poland.

fCllBD; 1D01TS; BB51TH; TIITI
CCBPOOMDS: lIBllaTIOl


ether detail: glTea
Crrogenlc saipllag technique.

Bealthr allltarT and cirillan
eeployees, O.S. »lr Force School of
lerospace Kcdiciae, ages 23-47 yr. 3
eiokers.
IIBIZVIS; CBIOBIIHTIt BTDBOC1BBOBS:
CEIOBIB« OFGICIC COIPOVVDS;
CB10BOBB1ZZIIS; FLUOBIIE COBPODlDS;
EDIITR; HCOB01S; TZXtS; IDOITS
BErZIBBCZ



Itralenski. J.
Oobeckl, B.
Groaiec, J.
1980
British Journal of
Industrial Bedicine
37:373-374







ConJcle* J*P.
Caap, B.J.
Welch, B.B.
1975
IrchtTes of
Environaental Health
30 (2)! 290-295





                                                                                                                                                                                             CO
                                                                                                                                                                                             NJ

-------
      e-m. cUorofJaoro- (S CJI
         cMeroflsoro-  (9 CI)
   m.*«
TIJSBB
W»9
Eceatk










UFOSIIS MOTE












auirticiz
BRTHOD
SC/HS











units
or cisxs
-
a











11*61
lot detexrted-a. 5« uoybr











mi
0.07 ng/br










..
6EIEML IIFOIBUIOI
C«ipomi ftoi uk>an origin, to
other details qln*
CXTogeaic saapliag technique.

icalthr lilituy and civilian
tiploTees, U.S. lit Force School of
lerospace ledicise. ages 23-H7 jr. 3
ssokers.
{IllntS: CgUMXIHEO BTDIOCUBORS:
CdOBin O8G1HC COIIOniDS;
caiOBOinzms: TUJCEIH COHEOBHDS;
I«1HB: HCOEOtSj THIS; 1I101TS
	
0E^£BEVCE
Conkle. J.P.
Cup. B.J.
Mick, B.E.
1975
lrctiT«s of
iBTirouental Maltk
30(2):2«-295





          tctcuckloro-  (8 CI)
Eth«M, tctcachloro-  (9 CI)
1IT-H-I
ea-ci«
II ISS.85. It 121 C
1ISSOI



3950
Blood







3951
Brain









3952
Breath













1IMSVEB BOOH | IHITtlCtt



Inhalation








Inhalation










Inhalation













HETBOD


8C-IC








GO-EC










OC













WttSBS | BUCK | BE1I | 6E1IU1 HF08BIIIOI
OF C1SES | | |
1
I
1








1










a) 29
b) «2

-------
 tbyleae. tetrackloco- (8 CI)
Etteae. t«tctchloro- (» CI)
C2-CM
It 1«S.«, » 121 C

1ISSO
3*53
tteatk
3*5*
Bceatk
3»55
3956
39S7
»
xuosviE to


nkalation
•talatlon
kaUtloa
1U1TTIC11
HBTBOI)
GC/iS
OC-9S
8C-BC
ec-sc
EC
B1MBXB
OF CUE

M (387
uiplos)



HUBS
lot detect«d-2. 0 ag/hr
tot 9! ren
ot applicable
ot applicable
applicable
BEil | GBIIMI ZirOIMIIOI | BEfEtEICE
1 1
1 1
1 1
0.3 ag/kr | Ftcvloa* eipcnre to compotmS. la t Cockle, J.P.
1 clker details give* I Ca*p, B.4.
I Cryogenic saaplUg technique, i lelek. B.E.
1 1 H75
1 Bealthr ailitary ud civilian | ircklres of
I eiplorees. U.S. Air force School of t Environmental He a It k
1 aerospace ledlciM, ages 23-17 jr. 3 1 30 (2) :2»0-295
1 stolen. |
1 1
1 ftnntSt CHOSIHTED BTPBCC1B30HS; |
1 cnoiiBS oBsirtc COBPOOIDS: i
| CIlOIOEMZHtS; FLDOBIII COBPODIDS; I
1 iiiHi: itccBois: THIS; unts i
i i
< i
2.6 ng/1 | teasared at !5 C aid 760 •• Bg | trataszfBslEi, B.C.
Seoeetric I 30.2V occurrence f Braneaa, e.g.
I I8«er ••< «ppsr on«-Sig»t Halts 0.51 I O'leill, B.3.
1 aa4 13.2 ag/l | 1»7«
1 I JoaruL of analytical
1 Beeltkr. 18-35 TC old. nonaaotinq. I toxicology 3:225-23*
1 oi tan blacks and cancusflaas. I
( CUcago, It. tWiJlr-contrellea I
I experimental conditions. |
1 1
I IBHTH; atCCBOLS; IILtfOIS; 1DDLTS; I
| CBlOKiriTEB irDBOCJBBOMS; rOUTHI |
( cxeavic COBPCOMS; SEU.TH sir IB us; i
| IBRlUTICl; BBTalOLISS; BZTaBOlIIES; I
| EOPDUTIOB IIPOSOtE; OBB1I 1BI1S 1
1 f
1.0 eg/kg I Utopjy, 2* kr after deatk, dose I Lev lire. B.
1 indetemiBed. | rlerro. B.F.
1 1 Coze, S.».
1 53 rr old, 70 kg, dry cleaner, tt. ( Talaatoor. I.e.
1 1 1991
1 VltSIIU; 1D01TS; iOTOPSIES: BIOOD: | Journal ot Forensic
I fB»r«; 5IOIITS: LITBB; LUB6S; | Sciences 26{1) :206-20«
1 fcinstc BtcicisE; CBIOEIBITED i
1 *T9(oc»sBcrs: iiroasmu iccioevrs; t
1 OCCVPITIOMt MZ1BDS; UDDSTBUL \
t CBE'ICILS |
1 {
0.0 sg/kg 1 lutopsy, 2* kr after death, dose I Lirine, B.
I gnl«tenl>ed. | Plerro, B.f.
1 1 Goza, s.v.
1 53 yr old. 70 kg, dry cleaner, n. 1 falentoar. J.c.
1 I U51
1 incznt; IBOirs: inofsitsi BLOOS; i joaroal ot Tor en sic
1 ItHV; SItltTS; IITE8; 10I6S; | Sciences 26(11:206-20*
| 'CBMSIC lltlCIB!; CBLOBUWID |
| EIDBOCUBCIS; HDJSTBIU 1CCIDEETS: 1
1 OCCVMTrolIt niHBS; ITOHSTtHL |
1 CBJnrciLs |
1 1
1 1
.0 ag/kg t litopsy. 2* kr after death, dose ( t«ilee, B.
1 nd«ter«ined. | rlerro, H.r.
1 1 Got*. S.I.
1 f3 TT on. 70 kg. dry cleaner, Tl. I T»l«ntoor, J.c.
1 1 »«1
1 iiisiin: >iat,TS: IOTOPSIIS: BLOCK: t joernal of forensic
1 EB»I»; tcnniS; IITEI: must I Sciences 26 (1) : 2 06-20*
| fCBZISIC 
-------
 BttvleM,  tetracMoro-  (8  CIJ
 ctaeae, tetncfcloro-  (9 CJ>
 IZ7-M-I
C2-CH
SI 165.85.  BP 121 C
                                                                                      (CORIKIED!
T.ISSBE
3SS8
Briw











EXfOStTBX BOOT!
Inhalation












1ULTTIC1L
BZWOD
Caloriietrr












rorasE
Of C1SBS
2












SWGE
» 1-7. a 19/1
b) 0.3-5 a«/l











BE1B
a) lot given
b) lot given











GEIEBll IIFOIBITIOR
a) Start of exposure to peak at 10
he. 2.3 aq/1 at 22 hr
i) start of exposure to peak at 12-20
ht. (.3 sq/l at 25 nr
]c triehloroacetie acid after
eiposure to tetracbloraethvlene
vtpors (390 ao/1) orer 6 hr «iti t»o
30-aln brcats. sliainatioa only a
fc« percent of dose. ZstiaateA froa
graphs.
fclntMti
TC11I9; UBIIE: lETtBOLISB;
CELOBIIITIC ETDBOC1BBOIS
er re MICE
Bolanovslca, V.
Golacka, J.
1»72
Belrcyna Pracr
2C23):109-119;
TC-78-0130







     eae, trlckloro-  (« CI)
Itkaae, trickloro-  (9 CD
19-ai-6
C2-B-C13
g?  131.«».  gc 73 C,  B» 87.1  C,  It 100 n 8g at 32 C
USSHE


3959
Blood












3960
atetth











EIWSUBE SOOTI


Inhalation













Inhalation











1I11ITICK
HITHOD

GC













ac











BTFiBES
OF C15SS

«













<











sue:


a) 0-2.6 09/al
1) 0-1.3 119/mi












aj 0-38 pp.
b) 0-11 ppa











n&i


a) lot givea
b) lot given












a) lot gliren
b| Bot ?i»en











611 HiL IIFOtBJTIOl


a) 0 aad E hi after start of 100 ppa
for 6 hr. Final valve, 0.2 uq/»l at
2« hr
b> 0 and » hr after start of 100 ppi
foe C hr plis etaanol pretreataent.
final Talae, 0.1  at 21
bl
t) 0 aid 5 hr start of 109 ffn for <
«t pins ethanol pretreataent. Final
valve. < 1 ppa at 2* hr. Ethuol
qiven to naintaia blool level of
0.06«. Bstinated fros graph.
20-2« rr old stadents, *t 62-77 kg.
(ElCBIIIlTED EIDBOCiSBOlS; ilCOHOLIC
»T1B1«ES: S100D; 910QD PUSH;
T15I1F: BCT1BCLITES; IP!T»BO1ISH;
ItTLTS; GESillY
BEFEBEIC! f
j
1
laller. 6.
Spassonski, B.
Benschlor. 0.
197S
irchives of ToiicoLogy
33:173-189








Holler, C.
Snassottaki. 8.
Censchler, 9.
1975
archives of Toxicology
33:173-189







                                                                                                                                                                                             OJ
                                                                                                                                                                                             Ln
                                                                                        (HIT PIS!)

-------
fthvleae, trichloro- (8 CI)
ttkeae. tclcUoco- J9 CI)
7t-01-«
CS-B-C13
S« 131.40, SP 73 C. BP ST.1 C, TP 100  u  «g  at  32 c
                                                                                      (COITIIUBD)
I 11SSOJ
3M1
Ireath
3962
Breath
3»«3
Ortse
ZIPOSOBI 100


halation
etWl
IIILTTICU
SBTBOD
IX
9C
OC/BS
SC/BS
IIBBIB
or CISE
4
a
0
tuet
a] sot given
b| (at given
c] tot given
d| lot gi««
a) (at given
fl lot given
»ot feteeted-3.9 ngyhr
•-22 «j/l
BE*« | CI1IBIL IlTOtStTIOI I JEWHMCB
1 1
1 1
1 1
a) 28.7 ppa | a) 1 ill after 200 ppa, 7.5 hr 1 stevirt, C.D.
b) 58.3 pp» | t) 1 «ti after 200 pps, 7. 5 hr, plus I Bake, C.L.
c) 14.2 pp« j ctbaaol { Peterson, J.s.
d) 29.3 pp» | c) 30 tin atter 200 ppi, 7.S kc I 1974
e> 9.9 pp« | a) 30 ili after 200 pp«, 7.S hr. plus ( trciirei of
aol |
I Ithaool doac, 1 qt beer or 90 •! 1
1 *o4fca after 5.5 hr of TCE 1
1 1
1 BealthT 19-»6 rr olds f
1 1
I Tasodilatatioe. of saoerficial resaels 1
j <* face, cheat, shoalders, tetveea 1
1 xca^olae, peaking at about 30 iln, 1
I »«dinq \>j *0 iln. Lesions not I
j accaapaaied tT subjective response, 1
I at changes in blood pressure, 9K0, t
1 etc, iriaalTEts, 501-12 panel. I
t t
1 ICIIIS; DZlRHITIS: 9IUTB: DBH« (
1 inmciioi; ticoHoxs; ceioeifs i
I cioisic comcoivs; BIILTB BIZISDS i
i i
1 1
0.54 vg/hr I Fievioas expoamre to cosponid. iro 1 Cookie, J.P.
1 ether detail* qivea ( Caip, B.J.
1 Cryogenic saapliig techaiqne. 1 Belch, B. B.
1 1 1»7S
1 acalthr nilitarT and ciTilian 1 Ircaive* of
1 eiploreea, V.S. lie Force School of 1 Enrironaeutal Health
1 lerospace ledlctne, ages 23-47 rr. 3 1 30 (2) : 290-21 S
1 siokers. I
1 1
1 CEIZniSi C8IOEIIITZD HTO«OC»BOHS; 1
1 CEIOBHE OBSinC C08MOTDS; I
I CEicsoBimms: nvostiE coapoorns: i
1 IBI1TI: ItCOgOLS; TIT IS; «D01TS I
1 1
1 1
0 • or - 5.9 ig/1 | it trlehlocoethanol (Mtabolite) 1 Perdelllai, t.
1 Data also on solvents In factory air 1 Bragnoae, T.
1 t Pavan. T.
1 letters In shoe fact or T in Italy i »*«0
1 I Toxicology and Ipplied
1 DIIIB: 8TDBOC1BBOIS; IPTIBOLITES: | PSaraacOlogf 53:220-229
I nttT; HDismii inosptrzoss; i
1 HtUSTSIlt ITSICfE; US PO[tUTIO»: |
1 CCCOP1TTOIII OISEtSES {
1 I
                                                                                                                                                                                           U)

-------
 FthFlew,  t,1-dlcUoro-  (8 CD
 I«k«M,  M-dichloro- 19 CI)
 TS-3S-*
C2-M-C12
II «fi.9«, » -122.1 C,  BP 37 C, TP 100 •• B» at 15 C
JISSOI
39«»
Breath










EXPOS*!* IOSTE












tiaimcu
nTBOO
«vas











IOIBES
OF C1SK
8











sues
»ot detected-13.0 ao/kr











mi
1.6 ag/hr











esiuii IIFOBHMIOB
Previous eiposare to compound, lo
ether ietailc aiven
Cryoanic saiplin? technique.

lealthr "Hilary ud civilian
employees. U.S. ale Farce School of
lacespacc Xilicina, aq«s 23-4T jr. 3
scoters.
EIRZISS; CHLOBU1TEC BTBEOC»EBO»S:
CHLOBII1 OI6UIC COKPOnilDS;
cBio?oBEii!«is: nnoBi» coiponns;
EB!»TB: I1COBOLS: TCT15; IDDITS
UFEIZICE
Conkle. J.P.
Caip, B.J.
Velck, B.E.
1975
KrchlTcs of
EaTiron«ental Health
30{2):290-MS





ItkyleM, l,1-«lcliloto-2,2-bis(p-cliloropbeiijl)-  (8 CI)
ECIMM, 1,1*-(dlekloroetlM«illteM)bls|a-ckloro-  (9 CI)
12-55-9
CK-S8-CH
B« 318.02, K 88.• C
IISSTJE



39«S
lAipose
























39(6
liipoae









BIKJSUBB «OHT1








































IIIITTICIL
8 IT BOD




























GC










*
-------
Itajlane.  1.t-aicUoro-2.2-bis(p-caloronhearl)-  (« d)
MBxeae.  1.1*-(aicaloroetaeB)li4e»«)bis(*-caloro-  (9 CI)
7J-55-9
81 318.02.  IE 88. « C
1ISSI
3967
idipos
3968
laaioti
fluid
3969
Blood
1
3970
Blood
EXfoson loot




B liUYTICaL
BETBOD

ae-BC

X-K
(OSBEB
OF CaSSS
•> 27
*) 1
Cl 1
SO

25
IS
10
iaiG>
•) lot giTea
b) lot giten
c) lot alien
2-21 ppb

•-32 ppb
13-281 fpb
32-325 cpb
Mil | SZIZB1L IIFOBBaTIOl I BEPBBSIC1
I 1
I 1
I 1
a) 11.9 » or - 9.70 | •) Bospital patients 1 Inon. T.
ppi | b) 13 yr old feaale rfth Yusho | Ibe, 3.
b) 1.C ppa, f«t basis I el •« jr old aale »ith chronic PCS { Takaaatsv, H.
O 1. 5 ppa, fat basis | fot»nl«<} I loki, I.
1 i Him. s.
1 Japan 1 Fajiwara, K.
1 1 1975
I fClTcnORIMin BlPenitS; DDT: 1 rafcooka Sedical Joarna
| lIHCnOBOCTCIOIIMKEi BLOOD PlISBli 1 66(10:610-616
| lEOniSRS; JIF1I; GlSTBOinSSTIUL I
| SISTI8; PESTICI9ES; IDIPOSf USS0E; 1
I IITZg; KIDIBIS: OBEITVR 1
1 1
10.51 ppb f ao poaitirc apociaaas 1 Sazeaar B.C.
Seoaetric I I S*th, T.D.
1 Itegaaat towa, aiailic IB ' 1 Bahajan. P.I.
I sociovcoaoaic ler«l and diatary 1 1910
1 tabits. Ho occopatioaal or I International Journal
1 accid«»tal exDosare. I»c!cno», India 1 of EnTicoaaental
1 1 inalitical Cbeaistry
I EISTICIDIS; CRIOiniTSD HTDBOC«BBO»S; | 7:2*5-251
1 ciionis oieinc COBPOOIOS; ODD: DDE; i
I tCT; I«OI»; FBESIHCT; 1BIIOTIC 1
1 HOIS; P11CIIT1 1
I 1
1 1
I ICTle* I Deictaann, I.B.
1 | RacDonali, ».E.
I iipoael perscas in th« United states, 1 1977
1 tne Watkeclaads, S*ctea( larwl, 1 Ecotoricology and
j Japan, USSB, Poland, Garaany, India, j Earironaental Safety
I Bolqaria, PakistaB, lastria. | 1:19-110
1 1
1 Mpoctel cases of hypertension, 1
I elentei seraa cholesterol, abnoraal |
( IZGs* or iapairaent of nearoaascolar I
I function after acate exposere to 1
I coabinations of pesticides, bat aost j
1 data shoe nc adverse effects after j
1 Icng-tere occopational exposure. 1
1 1
1 iisr»i»: raiGtKii: GIRBIIT; HTDI»: i
r issin; J»P»I: (XTBESLUDS; PIKISTH: i
I ICIIID: sDssii: s«E9ii; DIITED i
I suns: IDIPCSS TISSUE: BLOOI; BLOOD i
1 EltSU; B1CCD SSIOB; SHT180CITES: I
1 itoirocTTES: mi; nsiit: stntt; i
1 BtltTfl B1Z1BCS: OCCnPITIOBIL BaZtSOS; |
1 PCPBHTIO« ZIPOSOBE: IFOPllSBS; I
1 PISTICIDIS; CBLOSIBE OBS1IIC |
1 CCBPODVDS I
1 1
1 1
12.6 * or - 70 ppb 1 a) Coatrols, fall-ten pregnancies t Sanaa, B.C.
57.8 * or - 65.3 I t) Pre-ten cre^aaacias I Siddlgai, B.K.J.
pb j c) Spontaneous abortions at less than j Seta, T.D.
163.8 » or - 105.2 1 t w* I Krishna Horti, C.5.
b | 1 Bhargara, i.K.
I Bcalthy, non-«xpO9ed, pregnant voaen, 1 Ratty, 0.
1 age 18-32 yr, India. I 19t1
1 | Journal of analytical
1 11911; aBOBTIOf; IDOLTS; TITUS; | Toxicology 5:6-9
I tlOCD; PtlCXRl; COBP1B1TITE I
| ITltniTIOBS; CHLOBIHTED |
| BIDBOC1BBOBS; CBIOBIR OBGIBTC 1
| CCBPOtJUDS; IISBCTICIDIS; PISTICIDSS; I
| PISTICIOI BESIOOIS; POtHLlTIOll |
| tlPOSnii PBICBaBCT |
1 1
                                                                                                                                                                                       u>
                                                                                                                                                                                       CO
                                                                                 (Bill »aSZ)

-------
 ItkrlM*. 1.1-aickloro-2.2-M«fp-cklOTO«n«Bjrll- (8 cq
 BCIMM, 1,1<-(dieklorostlMnjlla«M)bls(*-eUoro- (* CI)
 72-S5-9
C14-18-Cl*
 I* 318.02.  n 88.« C
                                                                                     (COITIIOID)
tISSBB



»71
tood.
Lasu













3172
Blood,
plasna















3973
Blooi,
sens



















397%
Kidney









MOSBBB com






































































IB11YTIC1L I B9BBES
•RIOD I OF C1SIS
1
1
1 *) 27
1 b) 17
1 0 37
> d) 1
1 •) 1
1
1
1
1
I
1
1
1
1
•
1
SC |a) 139
1 b> 175
1 C> 199
1 4) 210
|
1
1
1
1
I
1
1
1
1
1
1
1
1
OC | a) 41
1 b) 19
1 c» 50
1 *) 28
1
1
1
1
1
1
1
|
|
1
1
1
1
1
1
1
1
1
1 1
1
1
1
1
1
|
1
1
1
1
UKI



lot five*
lot elves
lot «!*<•
lot aim
lot «.l»ea











) 0.8-43.5 ppb
b) 0.1-18.5 ppb
c) 0.5-7.* ppb
d) 0.3-9.7 ppb














a) 1.2-31 uo/1
b) 9.2-118 «9/l
e) 7.1-213 nq/1
d) *.i-« uoyl


















lot applicable










HI! | 611(111, IMOBB1TIOI | IBFE1EICI
1 1
1 1
1 1
) 29.1 » or - 10.51 I a) Hospital patients | Inou. T.
ppb I b) Euclated person* I Ibe, S.
) 35.6 « or - 22.65 I c) •on-esaciated' persons 1 Takasatsn. B.
pb 1 o) 13 yr old tesale with Tasho < lokl. 1.
1 21.9 * or - 15.95 1 •) 2* yr old aala wltk aplnstic 1 Biki. S.
pb I aiesie a«d atoaach eaacer I fajlvara, X.
1 13 ppb | | 1975
1 180 ppb | Japao 1 rvkaoka Bcdlcal Journal
1 I 6«(10:610-«16
1 FOITCHLOBIUTP) EIPBIITLS; BET: I
I BIHCBtOBOCTCtOBniBB; BLOOD PL»SS1: I
1 BIOEL1SIS; JIP1I; 6tSXBOIITBSTIIU. 1
1 SISTBB; fBSTICIOBS; IDIPOSB IISSO!: I
1 1ITII: 5IDIITS; OBEBTIII 1
1 1
1 1
a) 10.5 ppb | a) Bural blacks 1 Fiaklaa, J.
b) 6.2 ppb | b» Urban blacks 1 Priastar, L.E.
O 2.5 ppb | e) Ocbaa cancaslaas I Creason, J.P.
4) 3.« ppb | 4) Ural Caucasians 1 Bauer, T.
1 1 Blnaera, T.
1 urban aal taral residents of SC, [ Bauer, D.I.
1 Infants, cklldcen, adnlts, eUerly. | 1972
1 j taerlean Journal of
1 SOOTH CUOIII1; 1DD1TS; CB1UHII; | Public Health
I HCIil STODTBSi BLOOD PLaSHl; | 62(5) : 6*5-651
I CCHMKITI IttLTJITIOSS; ODD; IBE; |
1 ICT; BIB1DHIB; PESTICIDES; (
I ECITCBLOIIIITID BIPHCTTIS; *IP 1
I toiwreioi; rcoD commtnoi; i
1 PtSTICIDt ilSIBOES; VO?ITUTXOB |
1 IIPOSVtB; SOilL MtBlS; HKBII UttlS |
1 1
1 |
a) 6.9 a VI 1 a) General population - continental I Kranthacfcac, B.
b) 29 u/1 | central (ratal) 1 klebic-Kolbah, T.
c) 53 af/1 | t) Ceeeral popnlatioa - continental | Kralj, a.
d) 23 a«/l | foatk (urban) | TkalceTlc. 3.
Oeoaetric neans | c) Szposed (erkers - contiaaatal I Beinec, S.
1 aorth («rbu) ' | 1910
1 9) Exposed vcrkecs - contlaental \ International irchires
1 tootk (arban) | of Occupational anl
1 1 ZnTironnental Healtk
1 General population, aqea 6-79 yr. I «5:217-220
1 OccipationnllT exposed vorkecs. ages t
1 20-62 TC. IllMlaTla. I
1 I
1 TBtOSUTIl; BLOOD SEBOII; CBLOBII1TSD I
1 BTDBOCIIBOBS; CBLOBIB! OBSUIC |
1 CO»POO»DS: CtC; DBS; DOT; |
1 IHlCBLOBOCTCLOBETalE; PISTICIOES; I
1 CCCOP1TIOI1L HITIRDS-. PESTICIDE |
1 IZSIDOES; POfOliTIOI BXfOSBBI; B1B.1 I
1 IBIHi U8B1I MI1S |
-_..(• |
1 |
76 ppa (fat basis) 1 2* JT aid ul* ulth aplutic aienia I Inooa. I.
1 ail stauck cancer t »b«, s.
1 1 Takauatsu, a.
1 Japan 1 Joki, B.
1 t Hikl, S.
1 FCITCHLOBHIT1D BIPBHTLS; DOT; I luliwara, E.
1 BHlCSIOSOCTClOBnill: BLOOD PLISI1; I 1975
1 IIOfLtSIS; JIPII; GtSTBOIBTISTIIlL 1 fukaoka fledical Journal
1 STSTCT; PISTICIOES; IDIPOSE IIS SITS; | 66(10:610-616
1 1ITIB; KIDIHS: omTOR |
1 1
(HIT P1GI)
                                                                                                                                                                                          U)

-------
          1,1-aicsloro-2.2-bis(p-chlorojhenTll-  (6 CI)
Eenzene, 1,1'-(illcklocoetlieailidena)bis(«-ckloro-  (« CI)

C1«-B8-C1«
CI 318.02, II 88.» C
ttSSB
3915
I tier
3»7«
Bilk
3»T7
Bilk
1
1
I
397J
tin
39T«
Bilk
sirosoBB 10




estion
~ i
IRUYTICll
BBTHOD

SC-EC
SC/BS
-


•agora
or cis
1
10
25

21
2*
45
«S
1M6Z
lot applicable
•2.0-H18.5 «g/kg
(at glT««

0.935-2«.«06 pp.
0.535-13.407 pp.
0. 535-26. »0« pp.
lot given
BMf | 61BIU1 XBF01UTIOB 1 MMBBfCE
1 1
1 1
1 1
ISO ppa (fat basis) I 2* TT old Bale slta aplastlc aseaia 1 mom, I.
j aid stanch cancer | *be, s.
1 1 lakaaatsa, 9.
1 Japan | »oki, ».
1 1 Bikl. S.
1 soiiciuniiiTtD BiPBims: DBTJ i rnll«ara, n.
I nntcBioiociaoRnait; BIOOD PMSBI; i WTS
I KOPUSSS; J1P1I; 6JSTEOIII1STII11 | Fvkaoka Mdlcal Joacmal
| STSTIB; PISTICIDES: 1HIP05! USSQI; | C« (10t«10-C1«
I IITEB: KIDIIIS; OHSlCTS |
1 |
1TS.T ag/kg ( HctatiB? fetter* I Kodrlc-Silt, 8.
1 1 Salt, Z.
1 17-41 re oldi froi Slaronla Protlgca, | die, S.
I loqaalarla. | 1980
1 1 Pesticide* sonltorlng
1 TIGQStaTti; 11CTJTIOI; BH,Ki | joaraal 1» CDs 1-2
1 iiotccviaimon; JBBII IBBIS; i
< caeiimTiD eroBocassois: catOBiu i
1 oisinc ccapcojos; CRIOHOBHIBBIS; i
1 rci: BUT: BgucEioaocicioHiiuB; i
1 FISTICIOES |
2130 » or - 1*50 ppt ( Bilk bank aonota | Hacrol. J.B.
1 1 Jsqoith, B.T.
1 Callfociia | 1980
1 1 Vev Sagland Journal a£
1 CUIfOnil; ten-IS; BHK; 1 HediclM
1 •loiarrironTioi; LICTITIOB; DO:: IDT: i 303 (16) :9»s-9*£
I PSSTICIDIS |
1 1
1 |
1 B»i«r | Oaichaan. (.B.
1 1 HacMmald, V.I.
1 tsposcl peraeis in the Onited States, I 1»71
1 tae fetkaclands, s«ede», Israel. t Boot oxieo logy »d
I Japan, VSS9, Polaaa, Seriaajr, India, I EnHroBaental safety
1 Balgarla, Pakistan, Kstria. I 1:89-110
1 |
1 Beported cans of brpertenstcn, I
1 derated serua chalesterol, abnocaal |
1 lies, or lapalrsent of nenrouscnlat f
1 Inaction *fttr acute axposmte to 1
1 coabinatlom of pesticides, but lost I
1 data show no adverse effect! after (
] lens-tern occupational eiposnre. 1
I insHia: EBtsisri: estsitr; noil; i
1 ISSirt; J»PII; KTRI811BDS: T1KIST1I; t
I tciiio; BH5SU; SVEDBI: USHID i
1 ST»TIS; ICIF05E XlSSVii BlOOt: B1OOB |
1 PUSH; BICCO 3EBOS; ISTTBBOCTTES; |
I IWItOCTTIS; (IIIKJ WRI»I; BETIE1»i |
1 gitiTB sirtsrs; OOCVMTIOIIL BIZJBDS; i
I 5CP011TICK BXPOSOBB; JIOPUSHS; |
1 PZSTICI9IS; CBLOBIIE OSGaaTC 1
1 CCBPOOirBS I
1 1
«.64g ppa | «) (oral sctkera, fat basis t Pozo Lora, B.
5.833 ppa | \) Urban lotkers, fat basis I Berrera Barteache, 1.
6.263 ppa | c) 111 .others, fat basis | Polo Tillar, 1.9.
0. 11» ppa 1 d) 111 anthers, nhole ail* basis I Lopez-Gltenez, B.
1 Cata for sna of all pesticides and I Jodral Tlllare^o. a.
I ccifarisons vith valoas of other 1 Iglesias Perez, J.
1 lirestiaatoti X HE'KS; TTOBal IB? IS I
1 1
(HIT PIGZt

-------
Itliylene,  1,1-dlckloro-2,2-bi8(p-cklorophen7l)-  (8 CD
Eenzcira, 1.1>-(dlckloroetkeoylidene)bis(4-ckloro- (9 CI)
7Z-JJ-9
C14-M-C14
If 318.02. If 88.* C
                                                                                       (COITIIIIED)
tlSSdl



3*60
Silk, fat














3481
Oaentai








3982
Placenta











3983
Placenta














MOSOSS W30T1


























































atalTTICaL
KETIOD


ec-BC

























GC-EC












SC-EC















IOBBS3
OF C1SIS


















1









50












a) 25
W IS
at 10













BUGS



) lot given
) lot givan
I lot given
) lot given
) lot given
) lot given










lot applicable









37-19 ppb












*) 3-42 ppb
b) 7-5* ppt
C) 7-19S ppb













nil | exiHii iiroiRaTioi
1
1
1
) 1.71 + or - 0.88 I ») 1972, 40 saaples
pa | b) 1973. 31 saaples
> 1.98 + or - 1.51 1 <=) W«. " saaples
pa j t) 1975, 20 aaaplas
) 1.9« « or - 1.0» | «) 197S, 19 sa.ples
pa | f) 1977, 20 naples
d) 1.92 * or - 0.79 I
ppa | 100-1*1 lactatinq voa«n, 2 lonths
e) 2.02 * or - 0.99 I alter deliTery. Bes Wants of Osaka
ppa | Eca lecture, Japan, varied diets and
:1 1.60 » or - 0.6* 1 «n»irometit«l conditions.
ppa I
I J»P1I; aDDlTSs LkCTlTIOl; BIIK;
| EIOICCUHOliTIO>; PISTICIDIS; DD<;
I oi6»ic cmonn COHPOJIDS:
| fOlTCHLOSIIaTID BIPHIIILS
20 ppn (fat basis) 1 «* Tr old >al« »ith stoaach cancer
I
1 Japan
1
| ICLICHlOSHiTID BRBIITIS: DDT;
| BHICHIOBOCICLOHHIIE: BLOOD P1»SB»;
| ItO?tlSBS: JlPaS: CtSTSOIIlZSTIIaL
| STSTBI: PISTIC1BE5; 1DIPOSE US SOT;
| IITIB; HtHlIS; OMIT1JB
1
50.54 ppb | 31 positive specinens
GeoMtric 1
j Ptaqnatt voaen, siailar in
I iccloa-coaonic l«>el aafl dietary
j babits. lo eccnpational or
j accidental eiposnre. t.ac1cno«. India
I
| HSTICIDtS: CHlOlIltTIO HIDBCC»BBO«S;
I cnoBiii osGinc COIPODIDS; ODD; DIB;
I en; noil; PIISIIICT: IHSIOTIC
I iinio; ?i»cin»
i
I
a) 11.9 » or - 11. « | a) Controls, fall-tern pregnancies
ppb | t) Pre-ters pregnancies
b) 31.2 » or - 15.0 | c) Spontaneons abortions at less than
ppb | 8 «tt (inclades fetus)
c) 93.6 « or - 69.3 I
ppb I Bealtky. non-exposed, preqnant nonen.
| ages 19-32 it. India.
1
| IIDIa: tBCRTIO*: aDOITS; TITOS:
1 110CD; PLlCIRa; COBPlBiTITI
| ITHOlTIOIS: CH101II1TIO
| BYtSOCUtBOlS: CHLOBIK ORCkllC
| CCRfOTKDS; II5ICTICI9ES: ISSIICIDIS;
| fISTICIOI HISIDDES: POPtlLlTIOl
| HPOSOBS: PBIGIilCI
1
BEHBEICZ



Takasaiji, T.
Vataaabe, I.
Knvabara, K.
ToshUa, S.
Koyaaa, K.
Huita, 1.
1»79
International archives
of Occupational and
Environmental Bealtn
»3:1-15





Inoae, T.
Abe, s.
Takanatsa, B.
>okl, I.
Biki, s.
Fnjiwara, K.
1975
rakuoka Badlcal Journal
66(10:610-616

Saxena. I.e.
Setk. T.D.
flahalan, P.I.
mo
International Journal
of Environmental
analytical cienistry
7:245-251





Saxena, R.c.
Siddiqai. B.X.J.
setk, T.D.
Krishna Rorti, c.s.
Ehargava, l.K.
Kitty, D.
1981
Journal of analytical
Toxicology 5:6-9








-------
flsorlte
1698*-*8-8
f
It! 18.998*



1ISSVI
398*
Hood.
plassa
3985
Blood,
Plasaa
39tf
Hoot,
ser»
87
lie
3*88
Brill*
BirOSOlE BOOTS aULRICU
BRBOD
lagestios ISj
Isgestlon

lahalatioR
Tngestlon
colorlMtry
ISB
ec

s
•DUES 1 I1I6S | mi | GtllBlL IIPOBS1TI01 I 1SFI1BICE
or C*SM 111 i
III 1
III 1
* I ») 1«-20 »g/»l | a) lot give* | a) tefore vanish application to 1 Ekstrand, J.
1 b) 60-120 ng/nl I b) lot given I t«eta I Koch. G.
1 1 | t) attar Tarnish application to | Potersson, L.B.
1 1 I teeth, dose 2.3-5.2 *9. peak at 2 hr 1 1*10
III I Caries Besearch
1 1 1 «-1» Tr olds | 1«: 185-189
III 1
I i i FtnoMDE: BICOD nasai; CHUDBM: i
1 1 | Mill: SIIDZI |
iii i
26* | a) lot gi.ni> I a) S. 00 » or - 0.27* | a) 10-20 Tr old* | singer, 1.
1 b) lot given | oaol/1 1 b) 21-30 Tr olds | cphaog, I.E.
1 c) lot given ) b) «.7» + or - 0.216 | c) 31-«0 yr elds I 1979
1 d) lot given i naol/1 1 d) «i-so yr olds I clinical Cnenistry
I •) lot given | c) S. 58 * oc - 0.316 | «) 51-60 re elda I 25 f«> SS23-S25
1 f) lot given | nsol/1 | f) > CO rr old 1
1 1 d) 5.«6 » or - 0.295 | Ifter consoirtton of fluoridated 1
1 1 naol/1 | »it«r (1 aa/1) > 1 yr I
1 1 •) S.«7 » or - 0.326 | |
1 I oaol/1 I Beside its of n I
t 1 f) S.58 * or - 0.3*2 I I
1 1 naoVl 1 IIIIBSOTI: 1 CHITS; 1GS; CHIICBEI; |
1 1 1 IIOOD JtlSBJ: C01P1MTITE I
1 1 1 !1U0»TIO»S: FLOOIIEI; DBIIKIR6 «TtI I
III 1
1 II 1 " "'
1 • I a) 0.0*-0.06 ppa | a) lot giren { a) Controls | Obel. ».».
IB | b) 0.01-0.07 pps I b) lot given | b) laboratori persoBMl, > 20 TI 1 Socenson. S.D.
I *9 |c) 0.01-0.09 pps | e) lot given | eiposir* | Roach, D.I.
1 1 1 e| Frod«etiea vorkers | 1980
III I Isericaa Industrial
1 1 1 lerkers at aaaoaias | Hygiene Association
1 1 1 Ferflaorooetasoate prodnctloa plant. I Journal «1:58*-589
1 1 1 ftOOSIfl; IIDOSTBIll «ltRS; B100D I
1 1 1 snag: occqpnioiu. BI±»BBS: B»S: i
1 1 1 FlflCBIDl; PlIOBin COSPOOKCS; |
1 1 1 IIBUSTBIlt HMSPHSBES |
1 1 1 J
1 1 1 1 	
1 a) 6.5-18. e ag/1 1 a) 12.02 ag/1 | a) tofor* local exhaust ventilation I white. D.I.
1 b) 0.2-3.2 ag/1 | b) 1.«1 eg/1 | b) Ifter ventilation | 1980
III 1 Joarnal of the Society
1 1 1 Scottish factory workers exposed to 1 of occupational
1 1 1 "- I Bedicine 30:12-1*
1 1 1 SCCTLUB: OBIIE: FL001IDE; mnSTBIU I
1 1 1 aTIOSPBEBES; OCCOPtTIOIU. B1Z1KES I
'•I 1
1 1 1 | 	
1 a) lot gives 1 a) 100 ng/12 hr I a) Before Tarnish application to | Ekstrand, J.
1 b) lot given I b) 200 ug/12 hr | teeth. 2 yomxjer children | Koch, 6.
I c) lot given I c) 5SO ng/12 hr I t) Before varnish application to | Petersson, l-G,
1 d) lot given 1 i) 1. 100 ag/12 hr I teeth, 2 older children | i*«o
1 1 le) Ifter varnish application, 2 | Caries Besearch
1 1 1 voisger children | 1«:185-189
1 1 Id) after vanish application. 2 older I
1 1 1 children |
1 1 I rose, 2.3-3.0 nq for younger children I
1 1 1 and 5.0-5.2 19 for oiler ones |
III 1
1 1 1 *-1* yr olds |
III 1
1 1 1 IIOOBIDE; SLCOO PUS1»; CHXIBEII; |
i i i ciiiz; SIIBZI i
- - 1 1 1 1

-------
flierlM
7782-«1-«
r
Itl 18.99M.  op -2I9.«1 C, IF -188.13 C. If 100 mm Hg at -203 C
TISSBB
3989
Blood,








nPOSOBB MOTE









AIAITTICA1
HITBOD
ac








mass*
or CASES
at *
b| *
O »9








IAI6E
a) 0.01-0.08 ppa
b) 0.04-2. CO ppa
e) 1.00-71.00 ppa








mi
a) lot given
b) Wot glTea
ct lot given








GEBZBlt IirOBUTIOB
a) Coitrols
1) Laboratory personnel, > 20 jx
•xpoair*
c] Prodictioa tOEkeca

forkera at aiaoaloa
ptrf luorooctuMatat ptoonetion plant.
flOOBIR; IBEDSTlItl PLAITS; 8100D
SEBBH; OCCOP1TIOBU, BISABDS; BITS;
ItBCBIBB; TLOOBIIE CCSPOOIDS;
IIDDSTEIAl UBOSPBISIS
tEKBIBCI
Ibal, F.I.
Socenson, S.D.
loach, D.B.
1980
aaerican Industrial
Bfgiaae Aasociation
Ooarmil »1:58»-5B9




113-39-7
ei-BS-i-o
» 59.01, BP iao-ies c
1 ISSUE
3990
VElM











3991




BXIOSVB IODT1
latalatioa
Da rial











laaalatloa




AI1L1TICU
BET HOC
ec











5C




OF CaSXS
22











9




"BGB
a) lot airai
b) lot given
e) lot alien
d) lot qlTea










0.«- 19.56 .O/O.T




BUI
a) 19.9 * or - e ag/g
creatiaine
b) 63. 0 + or - 16
aq/g creatialae
e) 10.3 « or - 5 ag/g
creatlniae
d) 22.6 * or - 8 ag/g
creatiline







lot glTea




CIIZBA1 IBTOBBITIOI
a) Before >otk, 2ad da?
t) after wort, 2ad day (expoaare 92. «
* or - 21 ag/ctt a « kr
c> Before »ort 5tV Jay
d) After work Sth dar (expoaare SI. 7
* or - 7 aq/cn a i hr

31-»7 TT old voikera in acrylic fiber
factory.
icdoaiul. qastric pai».

VBiiii anitcmES; EIIGIDB;
CCCHPATIOI11 BAZABDS: BEALIB HAZAEDS;
H5HSTBIH AtRasmtis; IHBOSTBIAL
I11BTS; SJTBtl BADtCALS; IBBAlAItO*


20-29 TT old factory nortera, Japan.
I1IBB; 9ITA301ITBS: J1FAI;
CCCOPATIO»»1 BAZAB9S; BBA»B HAZABOS;
1IDOSTSIAL AlflOSPHCRES: ZIDVSTfiXAL
BHEEtIC!
lannerfa, E.B.
riTita, A.
Biqolet. ».
Eanbean, D.
Backet, J.S.
Roels, E. A.
1990
International ArchiTes
of Occapatioul and
CDTiroanental Bealtk
•5:1*9-203




Toneaoto, J.
SnznU, S.
1980
International Archives
of Occ«pational and
EaTiroaaeatal Bealtk
•6:159-165
                                                                                                                                                                                           U)

-------
  !oriMi4«,
  CJ-S7-I-0
  B» 73. M.  IF -61C.  IP 153 C at 760 •• E«. 7C C at 39 » B}, 25 C at 3.7 M Bo. TP 3.T  »  B« at 25 C
IXSSn
3992
trcata













I IIMSOJJ SOnil
Inhalation














lULTIICJL
RETROD
BC














BOBBM
OF C1SBS
a| 5
it a
C) 7
d) 9
•1 8
a ^
« «
h) 5







iiies
a) 4.9-2.9 ag/cu
b| 0.4-2.4 ig/cg
c) 0.»-2.a lo/co
4) 0.1-2.9 ig/cn
•1 0.7-5.1 mg/cu
f) 0.7-».9 «g/co
9) 0.7-7.1 cg/ca
k) 0.7-*.« «9/ca























an
a) 1.7* ig/cn >
b| 1. t »g/c« •
c) 1.27 *g/aa •
fl 1.5 »g/c« •
•) 2.23 *g/ca •
f) 2.07 iv/eil •
3) 2.( >g/ca •
h) 2.3 «9/ca i







6XKML t»ro«mrioi
•t 0909 ir
b) 1000 kr
cl 1100 hr
91 1200 kr
«) t*0» kr
tl tSOO kr
41 1600 kr
h| 1700 kr
saifle tlmfs dorlag • kr shift
lectots In artificial lutt*c
factory. Italy
Hill; tDDLlS; BHaTB: SOLTBWT3:
FUBISl HJ1LT1 RAZUDSs K005TEUI
JITO3PHMZS; I»B1HIIO»; OCCOPlTIOJil
I111IDS
unuicB
BTtgnoM^ F.
Parbcllial. 1.
CalCnri, I.
IfSO
Britlak Journal of
Iniustcial HeiiciM
37:1«5-1«»








fatal
|tO-00-9
t«-a«-o
>1 68.07. RP -8S.6S C,  BP 31.3C C
I TISSU1
1
1
1
1 3993
1 Breath
1












39««
tr«atk













BIVOSHIE ion
















. _
















1I1LTTIC11
•erioo


ec/as














GC-BS














man
or cisss


8












_

5« (387
saaplvo}













Miec



lot d«t»ct«d-98.0 g4/hr














lot giraa














»B»» Giiitit urotBinoi



21.3 <9/
-------
tmllltm
7MO-55-3
c*
Itl C9.T2, ft 29-78  C,  BP 2*03 C
TTSSm
3995
laic

















ttttaam earn*



















1I11TT1C1I
SETHOD



















EOSBSS
or USES



















IMG!



















"*'



















GrilUL IITOSBITIO1
levin. 2* rei>rese«titl»e
pie-anal yds tceataents ace
tafcilate*. Tbe feasibilltT of a
kolistie, no-«ask policy foe kale
••alTsis is ootllmed a*d sapjoctei.
Kim: TBICI ntRSBts; s»ii;
*
-------
           *- (2-setarUe»zo7ll -
  C10-H11-I-03
  (1  193.21
1ISSOI
3»97
oriae











tZPOSOlt BODTI
Inoestlon
laaalatiOD











RRB09
BFLC











IVIBSS
or cisss
a) •
b) «
c| 2










(IKE
a) lot glvaa
b) lot gi»«n
c\ ff-O. t» sg/sl










fUt
a) 0.122 » or - 0.00*
b) 1.2 « or - 0.4
•g/al
c) Mot glma








GEBIIll ItPMBaTIO*
• ) 2» kr cxcretloa after 0.3«*
•*ol/kg oral dose of o-rylt»«. Peak
IB 3-* be
t) Ifter 3 ht exposure to 13» pp»
c-xTleae vapor. Peek at 3 ar
«> Paiatera. Xstlaated fro* orapa.
Diiraal variation.
volunteer!. Man ages 53 jc (oral) ,
«« rr 
-------
7MO-S7-5
Itl 1»S.»6«5, IF He*. 76 C, » 7700 C.  W  1 mm  Ig  at 1M» C, 10 •• Ig «t 21CO C
TISSIl



1000
*Waej




















W01
U*ar





















4002
laag






















nosns tagti








































































immcu
BKBOD


n





















n






















n























nrnra
or cisss


8
21




















») e
b] 20





















4 8
b| 9
d 11





















iiiei



< 0.00001-0.0011 ag/g
< 0.00001-0.0021 ag/g
•t «t



















*| < 0.00001*0.000*6 »g/g
bj < O.OOOCt-0.0010 19/t
tat lit




















•) 0.000080-0.0079 oq/g
b) < 0.00002-0.01* og/ij
e) 0.00024-t uA teatk 0-1.5 IT
\ la fttap I *•« 2-19 fc, gto»j II.
I cntcols, aqaa «3-72 rr. «ko llnd SO
I »i {xoa tb* factorr. S««4«n.
1
| !1!»S»: C1I»Z8S: IIDIITS: tITII;
| IVTCSt CO»»IITIfS mUHIOIS;
I iiDosTiiii tieinii nisniEim
1 siTBoes; imsoii: ustiic: CIDIUJB:
| CISIOP1; CnOROl; COtUT: COFPIl;
1 «CLH; iio«; umiuwi: HID:
| I1IMIESI; M1CUIT; ROITBPIim;
1 iTOswoBDS: ivaiBini: SCHDIOB:
| SIIHI35: 5I1TSB; Til: TOISSTII:
I IMC; II11T1 IK1SDS; UDOStlUt
i tiins; smms; Tmmioa
a) lot gi»e» I a) Coatrol*
b) lot gii*a | I) VoikarB, groaps I aa4 II
1
1 I«c«aaal r«flMcr and a»lt»r
I toikcn. »gai SS-7C jt, •z^oced to
1 Icavy actala 1-3 4acad«s. Tiae
I tct**«a rctlnaaat aa4 teatk 0-1.5 yt
I la gcoip I aal 2-19 it, groaj II.
j Coatcola> aq«a »3-7J ji, »ho lli*a SO
1 1 • fcoa tk« tactocr. $••!•>.
1
1 aiuii: ciouns: riwiis: mm
1 IBISS: COWUITITI mtOlTIOlS;
1 imosnm Bteins; msoBtatrr
I HIIO9S; niTisoii; iismc: c«Dnra«;
I cisn»: craosnii; COBILI: conBS:
| SCID; 1101; IHTBIIOH; LEAD;
1 iMsutsi: iiBcoiT; BonsriftHi:
1 {BOSfBOius: straiDlui: scitiiOR:
| Slltnil: SIITIE; Til; TOIOST5S;
I ZIfC; IStlTR BIZISBS: I»D9St8I»L
| tllrtS; SHSITCTS; TIUmiDB
1
a) 0.00062 V)/i | a> Controls
b) 0.0017 ag/g ( t) larkac qrcup I
c> 0.0023 og/g 1 e> lacker grnp II
nt »t i
a»li»os | tcc«*aa4 ccflMcr tai nelt«r
1 lockers, aq«i S5-7S yr. •xpaacA to
1 b«»TT wtaH 1-3 tacaft*-. Tiae
| t€tM«H ntlXWMBt U4 3«tk 0-1.5 TC
t tn group I and 2-19 TC. gtoap II.
I ccatcola, agas »3-72 rr. »1ia lii«l 50
1 k> fraa the f actor?. Svedaa.
1
f SHDZt; ClDtfmS; KIDSnsj 11TES;
1 toiGS: con?»iTin mintTiois:
I unnstatn. vtettrc; seisoaiBirr
1 stiBODS; ntHom: IBS me : CIDSITJII:
1 CISIUR: CBSOHWB: COBUT; corpn;
1 eciB: IJOP: I»TIM«I: LJ»D;
I 8»Gtnsi: tmcun; ROITBPIIOR:
1 ccosrwngs; BVBIOIHS; sctigioi:
I SHEfXIM; SIITEB; TH; TO«SSKIi
| -JIC! a«»lTB BIIJBOS; I1DOSW41
1 flirts; sunnts; TtLi0
Scl««c« of the Total
raviro*a«t 16:13-15

















Bcana, D.
locdbeig, G.
V«ster, P.O.
1980
Sctoace of tba Total
Ia»iro»«»«t 16:11-35


















(HIT P16IJ

-------
   «cia
   7440-57-5
   In
   I« 196.9665. HP 1064.76 C.  EP  2700 C.  TP 1 •• tig at 1869 C, 10 an 89 at 2160 C
                                                                                         (COETT.BOED)
TISSUE
«003
Hall















SIFOSHBE BOOM

















immcii
BET BOD
»
















101 BBS
Of OSES
a) 9
b) 11















sues
a) Wot given
b) lot given















mi
a) 2.64 * or - 3.81
PP»
b) 0.«2 * or - 0.32
PP»
Dry lit












GBIEBIL IIFOSBJTIOI
a) «oian
t) Ben
left thiab
Use revieved; knovn levels ot 30
other ele««ts

Bealtkv 20-60 re olds

HOLTS; SCI: IIIIS; BBflM; UDBIIHB;
IITIBOII: IBSCTIC; BIHIDB; C1DBIUS;
caicni: cisioa: CHBoaing.- COSIIT;
ccppra: eiBBiiinB; GOLD; isoi; uig;
xensiiiH; Hiieiiisi; RISCOXT;
lOlTBDIIBI; RCKBL; fOTJSSIUB:
BHBIDI1R: SBlZflOB: SI1ICOII; SILVIB;
joetnR: SIBOITIQB; Tt>: TITIIIHH:
1H1DIVJ: ZIK: ZIBCCIIDR
BZFSBERCZ
Xanabrockl, E.I.
Kanabroeki, J.I.
Greco, J.
Kaplan. E.
Oester, T.T.
Brat, s. s.
GastafsoD, P. S.
Kelson, D.I.
Boor*, C.E.
1979
Sclenctt of the Total
E>TiEon»ent 13:131-140





  Beptane
  142-82-S
  C7-116
  f« 100.20. IP 98.52 C. TP 40 •• Bg at 22.3 C
nssra
4004
Breath












FIFOSOBI IODTE














a»tmc*i
BETROD
GC-HS













inaaxs
or cisis
54 (387
saaples)












EIIGI
•ot given













BUI
1.8 09/1
Geonetric












GEIII11 IHfOBBlTIOl
Beanceil at 25 c and 760 » Hq
47. 0* occarrcnce
lover and upper one-Signa lialta 0.69
and 4.7 nq/1

BealthT. 18-35 ji old, nonsmoking.
nrfcan blacks and Caucasians.
Chicago, It. Rigidly controlled
eipcriaental conditions.
I1I1TB; JICOBOLS; I1LIIOIS ; 1DITITS;
CEIOBIMTII BTOBOCaBEOIS; 7O11TII.B
CfSUlC COBFCOMDSJ HULTH B1Z1BDS;
IIH»HTIO»; Brtuonsa; BXTIBOLITES;
COPOLtTIO* EIFOSOBi; OBB1I tBElS
BETBBEHCZ
Krotoszynski. B.K.
Brunean, G.H.
C'Belll. B.J.
1979
Jovraal of Analytical
Toxicology 3:225-234








                                                                                                                                                                                              oo
Beptan. 2,4-diaethyl-
;J13-2J-Z
CS-B20
(I 128.76, !F 133.5 C
tlSSBl
4005
Breath









t
t
\
»
EIPOSOBE EOUTI











\
I
\
\
1IJIITICIL
BETHCD
SC-BS











1
I
t
IDiBIB
or cjsss
5« (387
saiples)













illGE
lot given














mi
0.267 ng/1
Ge one trie











t
I
GEBBBli IRrOMlTTOi
(•asared at 25 c and 760 •• Bg
46. 5< occurrence
lower and upper one-Sig*a Hails
0.0«S aad 1.5! ag/1

1««lthT, 18-35 jt old, nonaaoltinq.
nrtan blacks »d caacasiaas.
Cfclcaqo, 11. BiqldlT contcolled
• xveriMetal conditions.
ISI1TH; klCCBOlS; IlltlOIS; UD1TS;
CB105T11TID BT9-BOC1BBOIS: VOIlTItX
ctetiic coiifcncs; BEIITB mziBis-.
llflllHTOI: BITIB01ISR: BI1WOHTES:
tcrnnTTOi ixtosims IBBM uzis

PIFEBEHC!
KrotosTjnski, B.K.
Brnnean, G.I.
O'leill, B.J.
1»79
Journal of Ualytieal
TOTicologr 3:225-234










-------
        ,  2,5-diMtari-
C«-B2O
BI lie. 25, tt 136 c
tisstt
»00«
truth












arosast WOTS














luimcu
BET8OD
CC-SS













» oasis
or ctszs
56 [397
oaipl«s)












fl»GE
flot givfll













Bill
0.083 09/1
Geoaetric












SBKBII nroaa»Tio»
aea*area at 25 C »a 740 II B«
21.25 occurrence
to»r »3 op par ooe-Sigia Halts
0.019 in a 0.353 Bq/1

BealthT, It- 35 TC oil. noniBOfcia?,
«tn black* u4 Caucasian*.
Chicago, IL. BlgUlr conttollea
etpcctMBtat condltioos.
ESIHB: 11CCS01S; IIUIOIS; UVLTS;
CB101IHTID BIDBOCHBOSS; 1014TILE
CBGIITC COBfCDUDS: BI1I.IB BIII8CS:
IHIHTIOI; IRtBOlXSI; RITtBDIrrES;
tCTDtlTtQI tlPOSDM: VSBK 1BUS
sxtttstcs
tratoazjncti, I.E.
Broi«»f S.B.
O'lteiH, B.J.
197*
Journal of In&lTtic&l
ToiicologT 3:225-23*








S«ptrl alcebel (a CI)
1-M;tuol (S CI|
111-70-*
C1-H1«-0
II  116.2. » -3».6 C. BE  175.8 C. TP  1  ••  Bol ci»ill«li
erplofeea, n.s. lit Torce Sctool of
l«rosp«c« fledlclnev a^«s 23-*7 rr. 3
stokers.
tllZEBIS: CIlQSIflLltl STDECCKBOSS:
CE10BI1! OBOinC COBCOraSS;
CElOSamtEIIS; FLDOEIK COHIO11BS:
fEUTB; II-CCIOL5! TEHS: 1DOITS

BEFZBEICE

Coakle, J.?.
Caap. B.J.
nelch, B.E.
1975
•rcoiTes of
Eavlronaental Bealta
3 0(2): 2 90-295




f
1
                                                                                        (SHI P1GZ)

-------
   ICXtM
   110-S4-3
   CC-11*
   B1 86.17.  BF  «8.7 C. T*  100  ••  Bo.  at  IS. 8 C
TISSUE

400*
£t««th












trrina










siposoB! BOOI














I»kalatio»
Bataal










1 ZURICH
9STHOD
ec-ss












ec/as











BOBISB
or cisis
5* (387
saiplas}











10











HISS

Krt »1T«












a) 0.1-1.4 ««yi
b) 2. 9-30. C •»/!
c} 9.7-5.5 »o/l
4) 1.7- 17. S aj/1








SBl»

t.7 a 9/1
6a>oaetrlc











a) 0.5 * or - 0.4
•«X1
b) 10.1 « er - 8.3
•9X1
c) 2.4 » or - t.7
•4X1
1) 5.2 » or - «.e
•aXl




SZBZZIL lirOIBITIOl

e«i»ar«d at 25 C aid 7«0 as Rg
6.9% occttic^Bca
laiar i*i »?F*r oM-Slaaa Haiti 1.63
a«< 13.5 aq/1
B«altkr. 18-3$ rr ol£, aonsaokiiiq.
ntln blacks and Caucasians.
Caicaqa, II. SioldlT coatrollei
«xp«riMatal conditions.
ESI1TH; HCOBOLS; 11LHOIS; IDB1T5:
CKClIHIfO etDBOClBBOIS; TOIITHE
cieinc coapctjiDs: BIIITB BITIBCS;
JiaiuTioi; miBoiisa: MTIBOLITBS:
IC?BUtTOB ElPOSOIt! UBBI* UZtS
a) Is 2-baxanl
tt Is 2,5-b«zan«aloa«
c) Is qaaaa-Talerolactow
S) Is 2,5-Ua*tk}lfaraa
9«tabolltai
lata alia aa animate In factory air

letters in ikoa factory in Italy
aaizfc: ITCIOCIZBO*S; BZIIBOLITIS;
Ilitt; IIDOSnill tTMSMEBES:
ncosnm treizzt: us roiLmoi;
occvrnioui DISUSES
nntEicz

KcatoazjuliU B.K.
BCQIMail, Q.S.
0'Walll, B.J.
1»7*
Journal of laalytical
Toilcolwjy 3:225-23*








Petballlnl, L.

Pa»a», I.
19AO
Toxiooloqr and Ipplled
Pbaraacologr 53:229-229






Kxan, 1-ctloro-
•M-10-S
C6-BTJ-C1
II 120.62, a* -«* C, tt 13* C
r TISSUE
«011
B»atn












zirosmi IOBT?














mtnicii.
BETROD
SC-BS













•mm
or CISES
S« (387
saapl«s)












*IIGI
•at gi*«













BUB
0.121 ag/1
Geoiatrlc












«ZBI»L IITOtaiTIOI
e«a««ra4 at 25 c aid 7«0 aa 89
27. ?% oeeatrcne*
lc««r aai app«i: oie-Sl^M 11 alt a
0.033 aad 0.«34 a.j/1

IcalthT. 18-35 rr aid, aonsaotiag.
•Tta« blacks u4 cagcaslan*.
Ckieago, It. Maiair-coatrolled
•x|:ccia«Btal conilltloas.
HEITR; ilCCBOtS; HLIIOIS; JOBtTS;
CKOSIUT10 ITOIIOCIBBOSS; tOUTILE
cs-:irrc cospcoiDS; RZILTI BIIISOS;
niitnic*: «ET»EOLrs»: SEWBOI.ITBS:
POPOHTIOI {IVOSKSS: tIBBaB IBZIS
SBrfgEJCI
Frotossreskl, B.K.
Bra«a««, G.a.
O'Mlll, B.J.
1979
.loiraal of Inalytlcal
loxlcologr 3:225-23*









-------
(nan. 2,3-«Mtarl-
;««-*«-!
cf-in
Bf lit.23, Bf 116 C, TV 10 •• Hg «t 9.9 C
TIS5BI

•012
Bnatt












BMosnE xoni














1IURIU1
8ETICB
K-BS












•MB!t
01 CUBS
5» O*7
caaples)












MKI

•Ot giT«»












mi
.
1.« •«/!
Sooaetric












CEIIBlt IIFOtBlTIOl

Bcamrad at 25 C and 760 •• Hg
31. 81 occittcncr
lever ul tppar ona-sLgaa litita 0.57
ami a. 5 »q/l

MaUkT. «-35 Tc old. nou«oki»).
•ct« blacka ua CMcaslaas.
Oileaqo, n.. Slqldlr controll«J
«ip«rl««»t»l coo4ltio»s.
HIKH; IICOBOIS; IUIWOIS: U01TS:
c«io»i»«m «n>*oc*iw>is: rautns
ciemc coBfcoiBS; anna snitos:
initmoi: IRIMLISI; Bnimms;
rOMUIIOl IIMSOKE; 0«B»« 11E1S
BirESZRCE

KrotosifiMki, B.K.
Sraneai, C.H.
O'Ksill. B.J.
1979
Jamal of lulTtlcal
Toiicoloqr 3:2SS-23»








IciaM,  ].3.S-trlMtkTl-
ice«-53-a
e»-B2o
II 128.1!, BP -1JT.8 C. BP 131.34 C
1ISSBC

Bctatk











EsnsiBB toon













auirncu.
BETVCD
8C-BS











B0BBH
or cisis
54 (387
•uples)











SU6E

lot gl»«a











BEil |

MOM trie











eniui uroBBnioi

Manc*4 at 25 C and 7(0 •• Bq
SI. If occirtem
t,o««E wd «pp*r oa*-sia»a limits 1.7
aad a, a aq/l
'
MaitsT. 18-35 yc aU, nomaoklag.
artaa black* and caveasiau.
Ckicaqo, IL. Rlqidlr coattollad
aipniMital coidltioas.
tlllTB: ILCOWLSJ I III SOTS; UV1TS;
CBlWltti jp nioVOClBMIS ; TOL&TZLS
CKMK coifcmres; BULTI aunts;
IIBltMIOl) 8BT1EOIISR: K11BOLITIS:
ictvuTioB iiposani; DBBM »Bts
BBf»«HCI 	 ~~

Krotoszyncki, B.K.
Bruwaa, S.B.
C'Halll, B.J.
1979
Joanal of laalytical
Toiioolojf 3:225-234







 9li«M. 3,a-dlMtkrl-
 583-W-x
 cf-ne
1HSBI
1
«01»
Braatk











ITKISDK BOOK














tlUTtlCU.
HCTBOD
«C-RS












IOI1II
or ctsss
54 (387
savplfed)











IIIGI

lot glTci












BEH

3.7 a a/1
Geometric











GUtllL IiraUTIOl

(caeared it 25 C aad 760 la Bj
43.2^ oecvrrcnce
ivme aal appar out-siqaa llaita 1.7
a«l 7.4 iq/1

BealtkT, 18-3S Tr oil, Bonaaoklng,
or tan blacka a»d caacaslaaa.
Chicago, It. Uoiair contiolled
eipariceatal conditions.
null: iiccEois; IILIIOIS; wuits:
CilOBlaiTID m>BOCllB01S; lOIJ'It!
cteiitc codtCTiiBS: HEII-H BIUEDS;
iimnTioi; imioiisi!: BSTIBOLITIS;
KPVUIIOI EIPOSOK; VIBtl alMS
MTttMCB 	


Brncaa, G.a!
O'leill. B.a.
1979
Joaraal of analytical
Totlcoloqy 3:22S-234








-------
   252M-93-1
   ee-«i2
   •I M.1S. IP -139.9 C, BP Sa.5 C. TP 314 •• Hg at 38 C
TISSJ1
S015
Breath











HPOSqES BOTIIB













IIIITTICIL
BETgOD
oc/ss












BUHESB
OF CaSBS
8












I1IGS
lot detected- 1.3 ng/kr












BEH
O.S «g/-hr












eiizFii I»FOSBHIO»
Ccapoml fres tmfcaovit origin. lo
ether Ja tails giren
Cryogenic saapllaq technique.

B«althf silitary an! ciyiliao
eaployees, D.S. lir Focce School o£
l«rospac« Heflicioe, ages 23-47 yr. 3
siokera.
BHIH'SS; CBIOBIIITtD BIDBOC1EBOSS :
CBLOaHI OBGIIIC COWOOSD5;
CHLOBOEjrZIUJS; FLVQBIRE COBPOUICDS;
E1I1TB; HOOBOtS; THIS; 1BOLIS I
1
EiriBEICS
Conkle, J.P.
Caap, E.J.
»alch. B.E.
1975
Irchives of
E3Tiroa«ental Bealth.
30r2)s2SO-295

.


1
1
   Blppmlc *ci«  (S CI|
                         cr>
  CS-M-l-03
  II 179.17. BP 187-188 C
TISSUE
»016
ntlna








I
EIPOSOSE BO Oil
I.halatlon





1
I
1
1
njirricii
HITBOD
HflC









(OH BSE
OF C1SI5
2









BlIGE
0.42-0.46 ig/ml









9E1>
Rot qirex









GEIIEIL moMlTIOil
Cccapatiosallr ezposea to o-rrlene.
Dliraal farlatlaa. istliatei fro a
naph

Kilters, lean age 32 yr

mm; arriBOLiTES; occwuioiti
HIIiEDS; POP011TIOI tlPOSOBE; BETBTt,
EIDICilS; PURS; MB1UIIOI

1
ElFItErCE
Ogata, I.
Yaaazalti* T.
Sugikara. K.
Shlaada, I.
gegaio, T.
1910
Interaational Ircbires
of oocapational aa4
EBTico»ental Sealtb
•6:127-13*

tlpplrlc acid, i-Mthfl-  (S CIl
ClTclM, I-(3-««tbrUw»OTl)-  (4 CI)
C10-I1T-I-03
CI 193. 2 T
tissn
•917
Brine










IZFOSD1B BOOT!
Ineastion
Initiation










lUlRicu
9ETHC9
OF 1C











»5BBES
OF CUBS
al •
« 2










EJIGI
a) tot glwem
b) 0.01-0.33 ng/nl










""
a) 0.200 t or - 0.007
aiol/kg
b) lot oiTea









GBItm n-OMHXtW
al 28 he «rcr*tions alter 0.3S8
nrl/kq oral dose of i-irlen«. Peak
IB 1-3 »r
t) Painters. Estiaatea froi graph.
IJnnal rarittlet.

(olinteers, *eaa age S3 re (oral) and
32 fr (spray painters) .

iBiit; annciiTES: OCCTPITIOIIL
EITISBS; TO?DUTIO> BIPOSUB!; BITBTI
IC»IS; Fi ! laKOS
SBTEKICI
Ogata, B.
Taaazaki, I.
Saaihara, E.
Shiaada. I.
KoyvfOf 7*
199(1
International archives
of occupational anj
Invironkeatal Bealth
•6:127-139



-------
   «ae  ft CI|
          (9 cii
»!-T3-S
C«-BS
•I tlC.2. n -1.IC, IP 112 C, W  10 U •• at  58.5  C
iissie

uw
tceath










«019
Breath












MMSOM MITI



























alURICtl
IRIOD
CC/BS











sc-ss













I-DBBEB
or cisss
s











M (Ml
naples)












MM!

lot 
-------
ladlaa
In
It* 1U.7C, t* 1SC.C1 C, 3P 20(0 C
                                                                                     (COIIIIOBD)
IISSOE



«02f
Brill





















•022
Mart



















•023
Eidaer

















IXMSOIB SOU


































































IMtTTICU
BETHOD


U






















u




















1


















mtn*
or cisis

























*> «
b» 2



















) 7
» 2

















IIIGI



«) fat glrm
b) tone detected
c) lot alten
d) lot firen



















«} tfot gives
b) lane detected



















I lot given
i lone detected

















»S»B | GZBIUl IirOBBlTIOI
1
I
1
a) 9.OJ « or - O.fl« | et irt | •) «ale*
(1«ll«n) | t) resales
b) lose detected I
1 Icoa a «roep of *1 autopsies.
I (oreaslc aedieal ezailnations, Japan.
I tales, aean aoe 40.4 re. resales.
I aeaa aoa 37.* re.
1
I TIICE E1ER1ITS; lUTOfSIIS: J1P1I;
1 iiDnrai: iismc: ciDBiira: COBU.T:
I CEBOUIB1: COIFZR; 1BOM; BIBCB8T;
I iiciis; siGHisnru; UHGIIZSE;
1 EOBIDHHJ ini!fOIT; SClIDIOTi
1 SlinUMi (TTtllOa; TtJtDIOS; ZIIC;
1 GC10; B10BI1I; LIT1B; (30BZTS;
1 CIBmOI; CIIEBEUgil; B!»1T; BOSCLIS;
1 PlICBtlS; SPlEIi; lUKS: 1OBT1;
f BETais; coiipasann EriLnirioss; sii;
1 FCBEIStC B'DICIII
t
1
t 0.93 * or - 0.06 I a) tales
g/g (vet «t) 1 t) Feule*
) ton* detected I
1 fios a Troop of 61 antopsies.
1 forensic •edical eiaalnatioas, Japan.
1 Bales, nan aqe ««. 6 rr. resales.
1 seen aqe 37.* re*
1
I iiaci ELEdins: ioTopsi»s: Jisu;
i iinBZfoi; lESEfic: CIDKOH: COBILT:
r CHBosni: cctPiRi IBO»: BEBCOBT;
1 1IEIOB: RaGilSIDIi BalGaiESE;
1 BDEIDIM: 1III90II: SCalOIIi:
i stums; nnnm: ntmns ?i»c;
1 BCtD; 3SOB1I!; I1TCT; KIBIXTS;
1 CISIMdS; CESIEELHIKi BtlST; ROSCIES;
1 PiiCBEis; SFISI»: mss: IOBTI:
1 BIT USt COOPIE1TITE ITllniTICHS: S!I;
1 rcizisic Bieicim
BTTEBBICB



Tatara, 1.
Sazaki-Tasnaoto, B.
Isaoo. K.
Tecal. B.
i»ao
trchiTes of
EiTlrotBental a«alti
35 (1) : 36-an















Takasa, Jl.
soztlii-Tamioto, g.
Isaac, K.
Tecal, (1.
19SO
irchlres of
tnrlronaeotal Health
35<1)s 36-0













'okava, 9.
Saiafci-Iasaaoto, a.
Isaao, K.
Teral, R.
980
rchlTes of
nrironaestal Health
S(T):36-M











(•BIT fa«C)

-------
7«0-7«-S
lit 11*.?(. 0 156,61 C. BP 2080 C
                                                                                      (COITIVIBD)
HSSDE



»02«
line


















«02S




















*026
BiBda


















ZPOSOM 1OOTI
































































ininicit
BETROD


a



















M




















U



















Brain
or cists


11
3


















al 2
bl 2



















a) «
M «


















inei



0.13 «j/9 (KM ft}
0.005 mo/9 («at «t|


















a) Bot 9Lv«n
b) Bon lataetaa



















a) Bat ait«
b) Bat fltan


















SEIB | OZIIttl XffOHiTIOB
1
1 -
1
) 0.03 t or - 0.0* I •) Bilas
9/9 fvat vt) 1 t) YavaLai
1 0.00* vg/9 »at rt t
Badiaa) | ?roa a araii of 61 aatopslaa.
1 total lie Mdleal araalnatloaa, Japan.
1 Balw. nil aqe *0.6 rr. (••ales.
1 Mas aq« 37.* re.
1 THICI tiRBiitS: lottusies: JIPII:
1 llOBIBm; 1BSEBIC; C1DBXITB; COBll*;
l cnoEin; corpEB; iBoi: BEKOBT:
1 tBinfl: "WiESina: BueiBESE:
1 BBBioxra; amson; scairemi;
I !ItE»TBlJ TIlaBIOB: nBIDTOB: ZIBC;
| 6CLD: SBoniZ; LITtB; KIBfllS;
| CttEB»m; CHffllLWRt HEIMJ BOSCltS-.
I tiBCBits; sritiBi toias: icni:
| BtTalS: COBtlBallTB BTalgiTIOBS; SEX;
I IOSIISIC BIB KIBE
1
1
at 0.07 « oc - 0.10 | a) Balas
B9/9 (vat vt) | \) Vaaalav
)| Bon* tetacttd 1
1 Ito» a qcoap of tl latopalai.
I fcraaslc aaalcal •laaioatloai, Japai.
I (alas, aaaa 14* »O.S rr. males.
1 i«ai &9« 37.1 Tr.
1
| tllCt Il*Bt«S: IBtOPSIES; JaPIBt
l itoBini: iBssiic: CIOBIDB; COBU.T:
t CnOHIOBi CCPFBB; tlOB; HEBCUSI;
l lit JOB; ai«BESV»: BIIGIIESE:
| J5BIOW1J IBTIBOBT: SCUDIOBl
I snniBB: TiniinB! nuDioa: znc;
I GciB: BBOaiBt: UTEI; BTDBITS;
f ciBEBRira: CIBESEUOB: BUBI; BOSCIBSS
1 IIICIE1S: SI1BBB; tOBSS: lOBTit
l amis; coflniiTiTE ETU.OITIOIS: SM-,
1 ICItBSIC BBtlCIWS
1
1
a) Bat aatactad t a) Balat
b) 0.02 * or - .0* | t) r«ial««
aq/4 (vat vt) |
1 Froi a O.EOIT of 61 iitop*ia«.
1 (oraislc ia4ieal •laainatloa*. Japai.
1 BtlM, Mia 19* *0. 6 ir. Taaala*,
1 l«a« aqa 37.* Tr.
1
l mci iLBiiits; mopsiss: JUIB:
1 atHBtni; 1BSEBIC; C1D8HJB; COBUTi
1 CB1CBTOB; CCPPiB) IBOB; BMCVBt:
1 11C1OT; BlSBISHIBi BII61BMB;
1 1BBIOIIIB: tlTIIOBtJ SCIBDIVB;
1 siirirafl: TKiitoii TIBUIOB: irtc:
1 «015: KOHni; im«; KIOiIIS;
1 CtlEBtUl; CHZBXILOB: BEaBTJ BUSCLBS;
1 t»C9EU! stinij inias; IOBTI;
1 BITUS; COBPUlTin ETallHtlCBS: SEX;
1 ictnsic nciciBi
1
UIZ1IBCI



Tafcana, B.
Sazokl-Tanaoto, a.
liaao. It.
Tacal. B.
1990
ircklfea of
inriroacantal Baaltk
( l»3 «»












Tnltava* H.
Satakl-Iaaaaoto. B.
laaao, I.
Taral, B.
I960
irohirai of
EnflroBBBital Ha«lt»
3Sf 11 136-4*













Tvkava. B.
Svnkl-Timaota. 
-------
   7««fl-7a-6
   III
   Itl 1K.76.  IP 156.61 C.  BF 2080 C
                                                                                         (COBTIR0ED)
IISSOE


»027
Pancreas


















•028
spleen

















EIPOSOBE BOOT









































liaiTTICAl
RETHOD

11



















11


















BOBBIE
OF CISSS

a) S
b) 2


















a) 5
b) 3

















Si BSE


a) lot given
b) Bot given


















a) lot given
b) lot given

















BEAR | GEEtBAL IEFOSR1TXOB
1
I
a) 0.01 + or - 0.01 I a) Bales
ug/g (vet vt) I t| Fenales
b) 0.002 ag/g vet vt I
(aedian) I from a group of 61 autopsies.
I forensic aedlcal exaainatioas. Japan.
j Bales, aean age »0. 6 vr. Fenales.
I neaa age 37.* yr.
1
| 1P.1CE EISBSBTS: AUTOPSIES; JAPAB;
| AlOBIRVR; 1BSEBIC: CADRIDB; COBILT;
I CBBCRIVR: COPPEB; IBOf; BEBCaBT;
| IICIBB; RIGBESIUR; RABGAEESE;
1 SOBIDIUR: 1BTIROBT; SC1BDIDB;
I jiLEiim: TITIBIOR; WRADIBB: ZIBC;
| GCID: BROHIREJ 1ITES; KIDBETS;
I CIBEBBUR; CE8EBE1I8B; HEIST; RUSCLES;
I PIBCSEtS; SPIEEB; LUEGS; AOBTA:
| BFTUS; CORPABATXTE STALHATIOES; SET;
| 10BEBSIC REDICIBE
1
a) 0.01 « or - 0.01 | a) Rales
ag/g (vet vt) | t) Pennies
b) 0.03 * or - 0.03 I
ag/g (vet vt) 1 Frov a grosp of SI autopsies.
1 forensic •epical ezaslnations, Japan.
I Bales, nean age 40. 6 yr. Fenales,
I scan age 37.* vr.
1
I IBACB ELEBERTS; AUTOPSIES; J1P1B;
I 1IBEIE1R; IBSEBIC; CIDSIOH; COBUT;
| CEBCHni: CCPPEB; IBOI: HEBCOBT;
I IVBIOR; BISRESIOB; RIBGIBESE;
I BQStDTIlI; 1BTIBOBT; SC1BSTDR;
1 SIlIBIUd; TIUBIOM; VlBiDIOB; ZIVC;
I GC1B; BSORIBt; LITEB; KIDIETS:
| CIBIBBIS; CIBEBElLItH: HBMT; MtJSCllS;
| P1BCBE1S; SPIEEB; IOBGS; aOBTt:
I RIT1LS; COHPIStTITE ETlttUIIOIS; SEI;
I IC8EBSIC BBDICIBE I
BEFEBEBCS


Tokava. fli
Saznki-Iasaaoto, a.
Inano, K.
Terai. B.
1980
archives of
Environmental Health
35(1):36-«»












Takava, R.
SaTOki-Iasoaoto, B.
aaaao, K.
Terai. B.
1980
archives of
Environmental Health
35(1):3«-««











ledine
7553-56-2
I
Itv 126.90«S, HP 113.60 C. BP  185.2* C,  TP (solid)  0.03 aa Bg at 0 C. 0.305 an Bg at 25 C, 2.151  a*  Bg  at SO C,  2C.T« mm Bg at 90 C
TISSUE
•029
Rair

















EIPOSOBE BOOTE


















1
IMLTTICit
RETHOD



















BUBBSB
OF CASES


















1
BUGS


















1
sei*



















GEREBil IBFOBBITIOB
Beviev. 2* cepresentative
pie-analysis treatments are
tatalate*. The feasibility of a
be list ic, no-vash policy for hair
analysis is cutlinei an! sapcorted.
EtTIIB; TBACt EIERSBTS; RAIB;
• OSIBatll: RUSDBEREBT 1ETBODS;
ftTlLS; PBOTZIBS; COBP1BJTIT!
IT»101TIO«S; ILORIBTR; 1BTIBCBT;
aBSEBIC; BHHIU3: BRONB!; CiDBIUB;
CI1CN9; CBICEIBE; CHBONIUH: COEILT:
CCPPEB: sail inn: Grsiisinn; soio;
ICDIIE: tpoi: LIITHASIS: IZ»D:
RisBESiaR: RinaaRESE; REBcniT:
BOITBDEIOH: HCKEL: PROSPBOBOS;
PCTtSSIIB: BOBID11B: SEtEBIOR;
SIIICO«: SILTEP; SODI1": STBOBTIOR;
seiftnt: Tils TiriittiiR: TOBOMER;
*
BXFESZBCE
Chittlebomigh. G.
1980
Science of the Total
Environment 1«:53-7S















                                                                                       (HIT PIG!)

-------
:«J-S6-2
tt 126.9045, IP 113.60 C, 91 1*5.2* C, TP [oolld) 0.03 •• Kg at 0 C, 0.30S •• flg tt 25 C, 2.154 aa Sg tt 50 C, 26.71 aa Rg tt 90 c
TX3SVS


4030
lair
















4031
Balr








Eitasora >oni





























IMtRIClt
BXTBOB


11

















n








ROB an
OT CkSIS


a) 19
W 15
c) 17
•) 12
f) 5














a) 42
b) 40








B1BGI


a) lot glT«a
b) lot giTCB
c) lot glTaa
4) lot giv«B
•) lot gi»an
*) lot givan














a) 0.059-1.055 «g/g
b) 0.015-15.167 og/g








Silt \ 61III1L IirORBlTXOf
1
1
1
a) 19.0 * or - 5.1 1 «1 Coatrola, at birth
og/g | bl Fnll-tara lo» birth wight, at
bt 110.0 » or - 44 | tlrth
og/g | «) fra-tara, at birth
c) 110.0 * or - 49.2 I 4) Coitrola, 1 BO
ng/g | a) Fall-tarB lov birthvaigfat* 1 ao
0) 28.5 » or - 26.1 1 I) Pwtara. 1 ao
og/o; I lailtis * or - SK
a1 112.5 + or - 44.1 |
ag/g i laaaataa in Balifai. pra-tara group
«) 575.0 » or - 113.2 I MM bicthaaight 181« g, 26-36 »lt
ag/g | gaatatioB. foil-tan lo* blrthwaight
I gtoap tean blrtk valght 2371 g, 39-42
i »* gestation, ant fall-tera controls
j aaaa birtkvalght 3590 g, 38-42 n)t
1
1 BUB: RKits: ziic: COPPIB;
I Biieuist: TIUDIUH: IODIBE: nnirs;
I s«x
I
a) 0.422 ag/g t t) Controls
b) 0.143 ag/g | b) Raltlpla celaroals pttlaata
Railans I Staples fcoa 7 scalp altaa IB «ach
1 iab]aet.
1
1 Cllllla; ICTUS; CERTMl USTOtJS
1 !1S11lth Tarioos raaal Uaaaaas,
tafora 41alfaia

ChlUraa, 5.5-18 rr
iioiEscERs; cnioan; Kititn
tlSUSK-. B1OOD: QBln; HIUOEIH.TS1S;
lUSDlHEn RRRODS; I10B; HRUS
1ERBZICC

Tnkava, R.
Siizaki-Taaaaoto, B.
laano, R.
Taral, B.
1980
Itchivas of
Eivironaaatal Raalth
35 (lit 36-44










Ellis, D.
1979
Clinical Cheaiatcr
25 Pit 74 1-744



                                                                                       flER P1SE>

-------
atl 55.8*7, se 1535 c (para).  1000-1300 C  (east).  1SOO  C  (nought).  1300 C (steel) ,  B» 3000 C.  T* 1 u Bg at 1787 c.
                                                                                      (COBflBttBS)
                                                                                                                       10  ••  «g  «t  20*0 c
1ISSBB
•03*
ElOOd.
serua
1035
Blood,
sens
•036
lood.
Sana
«037
BodT
EirosBBi BOBT
ingest ioa


gestion
1U1RIC11
antes
us


dioaetry
•OBBBI
OF casis
al 26
bl 2S
c) 25
4) 20
10
*
(
g
25
12
| S1IGB
*) lot gl**>
b) lot gi*ea
c) lot give*
d) lot give a
•) «-18 OBOlaS/1
b) 3-15 aaoles/1
212-237 «g/dl
0.2-2. 8V of doss
0.6-1.5* of dose
0.4-12. rt of lose
1.2-8.51 of dose
nil I etttui iBToBBitroB t BEFEBIBCB
1 i
i i
a) 88 « or - 37 I •) Breast >llk OBIT 1 Picclano, B.F.
ag/100 ml | t) Fe-fortizied foraola (1* sg/gt) to 1 Deer ing. B.B.
b) 75 » or - 2« | * 10 I 1980
•4/100 ml | c) to-fortified foc»la (1« «g/qt) to I tnrlcu Journal of
O 9» « or - «3 | 12 «o | Clinical In tr it ion
ag/100 al 1 d) Ioa-tortift*d focaula (1.* ig/gt) I 33:7*6-753
1) 60 * or - 29 | tc » ao (differed sianificaatlr) 1
ag/100 al I * traasfacria satacation of fe) and d) 1
I •loalficaatlT lover. Data available I
I fer ages 3 and 9 ao. 1
1 1
| Full-tera 5.5-6.0 kg iafaata in 1
| Illinois 1
| le Set ieieacT la 2 cases. I
1 1
1 isoi: DIETS: niBoii: luiiois: BIOOD i
| SZBVR; COHP111TITE ETJI01TIOIS; I
| I1CI1TIOI 1
1 '
a) 11.5 aaoles/1 I a) Subjects aith noraal s«rua 1 Watson, v.s.
b) 9.5 uaoles/1 1 ferritin 1 Rone, B.
j b) Sablects sitk sabaoraal serua I Boore, B.B.
I f«rritia I 1980
I I tancet 2(8118) :236-237
1 35-70 jr alia. United Ungdoa. 9 I
| patients vith chronic blood loss* I
1 besipatesis, or i«nes»ctio» for 1
j secoadarT polrcythenia* 1 nornal |
| klcod iooor. I
1 1
1 DiiTED msoca: BLOOD SIBVB; BOUT; i
| BIOlCCOjnilTIOE; HETIBOLISB; IB TITO 1
I imrsis; IBCI; IEID i
1 1
221 ug/dl 1 Ittkritis patieats vita possibl* iron I B'Seffar, 1.
1 ttorage disease. j ronasier, T.L.
1 | rox. I.B.
| 38-!> rr old Canadians I 1977
1 f Journal of the iaerican
1 Jcint pain, cltrated transferrla I Hedical lasociation
I allocation, aneaia, deer east d libido, I 238 (17) : 1825-1828
1 iipoteace. i
1 1
1 reposition of heansiderin IB 1
1 lepatocrtes IB all, cirrhosis in one. 1
1 1
1 EIOOD s*Bna: itoi: CIHDI; icniTS; i
| SITUS: BETH POISOII1S 1
i i
1 1
> 0.71 of dose I a) ferric ortnophosphate 1 Bios, E.
1.0* of dose j b) Sod la a irca pyropbosphate j Hanter, B.E.
2.7% of dosa | e) Ferrous sulfate 1 Cook, J.D.
a.o* of dose 1 d) Bedaced iron, 5-10 u particle size 1 Saith, l.j.
s«oa«trie I t* suppleaeit foras IB a)-d) 1 Finch, C.I.
I « hole- bod T attake 10 days after last I 1975
I of flv« 10 g feedings of cereal 1 Pediatrics
I containing 5 *g P«- label led dose. 1 55 (5) :686-«93
1 Cata for other iroa nnpleaeats. 1
1 1
I 1-7 aoaths elds, lov socioeconoaic 1
I class, siailar iron nutrition. I
1 1
I ISOI; IMltS; DIFtS: CO<1Plt*tITt 1
1 TtimiTioiiS: urirts; BOOT: EBDGS; I
| IKCt EIBHEIIS |
1 1
tiBtt MSB)
                                                                                                                                                                                           oo

-------
lit*
7«9-89-6
It
Itl 35.9*7,
            0  IBS c  (pint,
                              tMO-1300 C (cut), 1500 C (troagkt). 1300 C lc >*4ieal aiMlaatiODi. Japaa.
j (»«t irt) I Halts, M«i aq» »0. « yr. ?«al«,
1 I •*» a9* 11. » TT.
1 <
I t met zuniTSi inomss; J»PII:
I t auniWi iismc; ciBBUjB: COBU.T:
I i cttoimis; COEPZB: IMC BIBCOTI;
1 i mm: itsitsniB: iiieiiist:
i i loeiDimi: imnon: sctnini:
1 i SHUTS!; Tiiunai; mtviaa: »K:
| | SC1D; nOBIIl; IITHS KIDfFTS;
1 \ cniBitM: cuamm; BUST; gosciis;
I i fiicitis; spine inras; IOITI:
1 | BITllS; COHPlMtm BTiiniTICIS; SBI:
1 i retnsie IIDICIH
1 1
a) lot giv« | a) 13.9 * ot - 1.1 t a) Global paUltos. 11 saiplcs,
b) lot 9iT«m | ••oVg 1 cMffleliBt of variation (C») 2C.6«
e) lot «i»«a I b) 12.8 * or - 0.7 I b) Camlat* n«cl««s, 11 maptes, CT
i) lot ji»am | aaol/4 1 11. *«
•} lot git«» | el 10.9 t 01 - 1.2 Icl tataaaa, 12 »a»plas. CT 38.81
IJ lot givaa I uol/g I i) Sabataatia ni^ra, « aaaplea, CT
1 1) 19.1 * or - 2.1 1 21.2V
1 aaol/g | c) Carabral cort«i, 16 *aapl«. CT
la) «.» » 01 - 0.» I 3i.«
1 aaoV9 1 I) llppocaapM. 8 saaplas, CT 26. »*
1 fl 2.6 t or - 0.3 1
1 aaol/4 1 titopiT Mipln
1 Dry «t |
1 ss i cttmu COITXI: iBtsomm BITSOPS;
t i ciicwi: ccptiij IBOI; MICKCSB;
1 | (Bill; lUTCfSIIS
1 1
•ot giT«a | 166.0 ag I C 1 «aapl«a at cat* of 1 !/•!•. 2-10
1 | »i» aCtcc taralai a arc *«UiB4 cods.
1 1
1 1 DalwsltT pVrsicB «kop, nocida
1 1
1 I fiotisa; HOLTS : BBHTB; ciictna;
1 1 CE101IIBJ CH9OHIOS: COVPBI: ISOI;
I i ttiB; uieiiisK: ncm,: potissiust
I t snrn: TITIITBH; TIBIOIOI; n«c; lit
1 1 fCILOTIOl; PMES: 1»SOSTSI»I
1 t ItBOSPBHES; TB1C1 ZIEIEVTS
1 1
1 1
a) lot givaa I a) 23 ppa I a) laanlaq 41nbl««
b) lot givaa 1 b) 22 ppa I t) Coatrols
1 1
1 1 t«»t»lm
-------
lioo
1MV89-C
»^ jy—»y w
it
U« SS.ga?. B* 1535 c (pit*), 1000-1300 C  (cast), 1500 C  (trtn^at). 1300 c (steel), B» 3000 C,  T? 1  » 19  at  1787  C,  10 •• agj
                                                                                    (coiiiioca)
•t 20*0 c
tISSO!

*0*2
lair




















«0«3
Heart

















*OM
Kidney


















SIPOStJBJ BOO






























































immcu.
SKIOC






















n


















n



















BOB BBS
or CASZS






















a) 8
W 3

















a) 16
> 3


















tIBCB























a) J.»-68 a«/« (net rt)
1) 19-73 19/9 l«t »tl

















6. 6-1(0 «9/9 (net it)
37-130 gg/g (mt vt)


















BBIB 1 fiEHBU. IBTQxBlTlOI
1
| Bavlen. 24 represeatatim
1 tre-analTais treataaats are
I tabelatel. The fcasibilitT of a
I Bdllstic. eo-iash policy for hair
I »ajysls is outlined anl support**.
1
| UllZt; TBJCt nitHRS; BUS;
1 USTBU.H: BIISOBIBBB* IBTBODS;
i KttLS; noTinsi ccwmtift
| IfUDlTIOIS; ILBBtlUI; 1RIBOIT;
1 itsmc: tuna: BHOBIIBI C»BBIOS;
t ciiciaj; csiciiH: cssomas: conn;
1 CCF*R; auini; cts«iiir»: eoio:
t ICDIIB; 1ROB: lliTHITOB; IBIB:
I MfiBMlfl; MIMIBSB; BgECtlBT;
| KITBDtmi: BICCZl; PBOSPHOBW;
I foTission; tmazii; sncnoR;
I SI1ICO1; SIItBB; SOBIOB; STBOTIOB;
1 SOITOti TIB: TITtnOB: TOICSTCB;
1 TIBC; ZItCO»JBB
1
t
a) 38 » or - 20 «j/g | a) Rales
(•at *t) | t) Feaalea
b) a* * or - 27 ag/9 j
(vet *t) 1 Itaa a 
-------
 Irei  .
 7«3 *-**-«
1C
Itl 55.a«7, IP 1535 C (pore), 1000-1300 c (east),  1500 C  fumaht).  1300 c (itecll, tr 3900 C. n 1
                                                                                                        *9 at 1787 C.  10 u Hg it Z0«0 C
1IS30I


4045
Kidney






















>04t
liver



















a 047
liver



















tOSOBS BOni




































































1BJIRIC11
imoi

























Ba




















u




















mesa
r cists

a
a
12





















) 3
b> 5



















a) 8
b) 9
C) 11


















IIB6I | Bill | 6EBIE11 IBMBS1TI01
1 1

51-148 og/g
40-513 og/g
27- 507 ««/?
•t vt




















a) 29-150 ig/g («et at)
b) 44-2*0 ag/g (vet vt)



















a) 81-391 ug/g
b) 111-796 ag/g
c] 91-344 io/g
Bet vt

















1
) 79 ag/g 1 a) Contrail
94 ag/g I b) torkar grcap I
54 ug/j 1 c) Writer qtcip II
et vt i
edtans 1 teceasad refinery a»d seelter
I verkers. agea 55-76 yr. exposed to
1 heavy ietala 1-3 decades. Tla«
1 tatieea retiremt aid deatk 0-1.5 jc
1 la groip I and 2—19 yr, groap II.
I Controls, ages 43-72 yr, vho lived 50
I ki froa tne factory. Sveden.
I
t SIUI*: ClBattSS; KID1ITS; liyiB;
I 10B6S: coBPaBiTiTi BTHBITIOIS;
I iBoasTniat iiftim: CTISOBEBWT
t IRBOOS; iiiiBOii; IESCTTC; c»omna;
1 cis in a; CBBOBIOB; COBILT; COPPIB;
| GOLD: IS01; UBTBMBB: tSlD;
I eifGMESI: HIBCVIT-. MtTBDXim;
1 fEOSPBOiis: BITBIDIDB: sciigitn;
I SILEVIN; SHVEB; TIB; TVBGSIEB;
1 II«C; BEI1TB B1Z1SDS; IBDHSTBI11
t ti»ns; smiTSSS; Tnivnna
i
a) 62 * or - 68 ng/g 1 a) Bales
(vet vt) 1 t) Veaalas
b) 150 + or - 83 ug/g 1
(vet vt) 1 Itoi a grc«f of 61 aotopsi«3.
I fereaaic aedical exaainatlona, Japan.
I Bales, aeaa age «0. » yr. Tesalas,
| aaan age 37.4 yr.
1
| TB1CI EIEBEB1S: 10TOPSIES: J1P1I;
1 tiBnBVB: iBsuic: cioaioB: COBILT;
1 CWCHOB; CCJSIB; isoi; BKBCDII:
| IBCIDB; SIGIISIDB; BIIGISESI;
1 JOBID10!!: IIKBOIT; SC1B9IOB;
| SIUIHJ1; TITMIOa; T1B19IQB: ZI«C:
| 6CID; IBOIfll!: tlVIB; HDIITS;
I CZlE9B>n; CIBtBEUIB; HE1BT: BDSCLBS;
I ElBClElS; SFUEI; LBISS; >O»1i:
I SITUS; COBP1B1T1YS STIHHTICKS; SII;
I fCBMSIC BIIICItE
1
1
a) 246 ag/g | a) Controls
b) , 198 ag/g | c) Vorker gtcap I
c) 139 ng/
-------
Horn
7*39-89-8

It* 55.M7.  BP 1535 C  front.  1080-1300 C (east). 1500 C (*ro*ait). 1300 C {ttaol),  »  3000 C,
n 1 n Bg «t 1187 C, 10 •• 1« at 20*0 C
1X359*



*0«t
LM«
•••"^

















•0*9
Ilia























•050
leaf














BIPOSO*! wnm






























































allLRXCU
BETBOD


a


















it























Boaabaeer















TOBBH | IUEI
or cuss i
i
I
3 1 112-280 ag/a |v«t M)
|
|

•
|
|
I
|
I
I
I
1

I

1
1
I
•18 It) 122- Kit ag/g
hj 9 | b) 80-«C8 19/4
d 11 |C) 32-»23 ag/g
I (*t M
|
|
|
|
1

|
|
I
|

1
|
I
1
1

1
1
1
1
1 a) lot glT«a
1 k) lot gi»a»
| c) (at gi»«»
1 d) lot 9iT«c
I e) lot gii«>
I f| Ht glt«n
1 g) lot gl»«
1 h| lot gl»«D
1 1) lot giwa
1
1
1
1
1
1
I
mn i GZIIUL imnnnoi
i
i
i
200 • or - It *q/g I «•!«•
(Mt *t) I
1 icot * oroip of 61 utapclcc.
1 £cr«««lc >«dlc«l •nilMtioni, Jap*n
1 !•!«, •••• 19* *0.t yr. r«ul«s.
I •••• •«• 3T.« yr.
1
i IIKI nuira: anaMiiS! JIPI»;
1 iioims: iiscvic: c»ai0B; cosnit
1 cHOBina; comi; 1101: nicni:
l utiva: iieiisim: nvemsi:
1 18110118: tMX80R{ SCIIDIOB;
1 snmira; TmiioR; T»«Binij sues
l cnir SBOMIIS iifras IIDIIIS:
I cnzsm; ninsuii8: auit: ROSCIIS;
| F1ICRI1S; SFISXI: 10«S5J JOKJ;
I iRiLS; coHmuin nkivuinsi SBI:
l fctinrc siDicifB
i

•1 303 19/9 1 *> Cootrols
k) 139 ai/g 1 fe) fotkct gtcav I
el 13* >4/g 1 c( >ork«r 9tc«» II
Mt *t I
Icdlau 1 t «••»«* rcflMrr >•< neltor
1 >otk*r>, aq*i SS-'e yr. exposed to
1 b«»Ty Mtal* 1-3 4*ead«s. Tie*
I t«tm« ntln**«t a*4 i«atk 0-1.S yr
j li gcaia I ail 2-19 yt, qroap II.
1 ccaitrols, a«a« *3-72 yr, *>o lii«4 SO
1 ki (toi tie factory. S«e4««.
1
l sitint cititBS: Knms: IITIB;
| ITJISSi COniHTIft SM1WTIOJS;
l iiDvsrnai nenn; ntsTinniT
I MtBODS: iniBoii; IBS me ; C»DKOB:
l ctsivt; citonni; COBU.T: cowsi:
1 COLE; noi: uirmoa: LZIDI
I iifeitEtt: ttncuti; aomntmis
l tcospaoiDi; tmiont: sen mm:
I 3 n mm; sitrsBi Hi; TOIGSTM;
1 TIIC; II11T8 UZUBS; I>DVSnial
t fiins; sannisi tiuoaian
i
I
I O.m | a) torial
) J. »5* | k) Beaosidtroals
) 1.0M | c) lette btoacaltia
1 0.16* Id) coalvoctcc
) 0.621 1 •) caalvork«i
I 13.5* 1 t} Boiatit* rarkar
1 1.99Y I q) TomlCT vetker
! 0.37* 1 h| coalvorlrec. Fir l»aloi
> 1.3*3 | 1) Saa* cotl«ork«r, excladlaq PIT
Feicent ixj *t 1 Itslos
1 l(aiarm«ta corraetad foi 4ist
1 coitait.
(
I vinio niGCCTi i9TR,n; nn«:
I KUSflinSIT BETHOTS.- I§0»; DOST
t
smmcs



Tak»a> B.
Sazqki-Ianaoto, «.
laaao, K.
Tacal. a.
1980
Iiekiva* of
UTiroaaoital Haaltk
35M):36-M












Braaa, D.
lordbacg, 6.
lastar, P.O.
1980
Scincf of tbe Total
Intitoaaent 16:13-35



















GDest, 1.
197«
laaala of Occapatloaal
Hygione 19:49-62












(KIT P16E)
                                                                                                                                                                                      N)

-------
 Iroi
7t39-»9-<
F«
It* 55.B4T,
            BP 1535 C (pin), 1000-1300 C (cut).  1500 C (ixoigit), 1300 C (steel), BP 3000 C, TP 1 •• Bg at 1787 C.  10  ••  Eg at 20*0 C
1ISSBI
40S1
Bncle
ton
taicnai
4053
SBllal
earl
MPOS018 MKI



1BIITTIC1I
SET «00
11
»
I-ray spectral
IOBBE8
or cisss
•> *
*> 3
«1 5
b) 3
•» 7
tj 12
Slid
) 11-54 n/9 (Mt •*)
) 1fr-»7 ««/« l««t *t)
«.) 12-48 «V9 <«*t «tl
b) 1S-67 »g/g («*t lit)
•) 28.»-1B1.5 »g/g
b) 24.0-122.5 ig/g
DtT *t
nn i Giniii MratMTioB
i
i
) 26 » or - 20 09/9 I i) Riles
|»»t »t) | t| nnlci
b) 27 * or - 17 19/9 I
««t »t) j Iroi • gtalp of «1 aitopllvi,
1 foMnie Mdieit oz*il»tiau, JapaB.
1 Btl«a, mi *q« 40. « Tr. T«Mln.
1 •«*• «g» 37.4 ft.
1
I T1ICI 11EBIKS; HTTOPJI1S: J1P1I;
1 tunng; nsnic; ciomtia: COBUT;
I cnogivR; come 1*0*: IEICUBT;
1 iieni: iiensiiM: iiieiitss;
1 Mturn; imaoR; SCHIHOH-.
| SH.HIOS; TITillOl! T1I1DIDS: ZIK:
1 eott: Bsoiiii; tun: ntins;
1 ctustTM: cisraeum: HSiM; ausciss;
1 PMCII1S; SHIER: 10«S; lOITli
I SITUS; COIPlllIITt OT110HIOS; SSI;
1 1C1MS1C B»K»«
1
a) 32 • or - 17 ag/9 I at flalvs
<»«t it) t I) r*aal«*
b) 47 t or - 28 ag/« t
tnt «t) | Iroa a groip el 61 aatopslec,
j teiamslc ••

-------
  Itoa
  7*39-89-6
  T«
  lt» S5.8»7,  IP 1535 C (pore), 1009-1300 C  (cast),  1500  C (noaght), 1300 C (ctMl) , B* 3040 C,  TP  1  ai  19 at 1787 C.  10 aa Kg at 20*0 C
iissm
*os*
SpleeB
















EXVOSISI tan*


















nitnicu
n

















Of USES
a| 5
B) 3
















mot
a) 57-«10 «g/g (net rt)
fc| 150-590 09/9 {vet vt)
















BZ»P
a) 369 * or - 1*0
og/9 («at «t»
b) 3*0 » ot - 330
a9/9 (»«t vt)














GZIZ111 MTOBB1TXOB
a) Bales
l| Teaales

fro> a group of 61 antopoie«.
forensic aeiieal examinations, Japan.
Gales, aean eoe *0*6 vr. Feaalea,
tean age 37.* jr.
imcj zizvzits: JOTOPSIZSJ ji»»»:
llORXBOB; 1B5Z11C: C&SBIUB: COZILT^
CnCBtOB; COmii IBOI; 5UC13HT:
Konn; Bisiisius; BHGMZSB;
•OfZDIOH; JVTZBOR; SCAmoB;
stinna; muian; TIIUIOB: z»c;
eciD; BioBiiz; iitzu: KIDXZTS;
CtBIBHIl; CZiZBIlIOB: BUST; B03CLES:
FMCtllS; SPIIEf i 1VKS; JOBT1:
9II11S; COD7IMTITK ZT»10»TIO»S ; SEI;
TCIZISIC B»ICX»
nnazBcz
Titkava, B.
SBinki-Tamaoto, a.
1KB9, K.
Teral, a.
USD

XBYiroiiMBttl Dealtb
35(1}:3«-M










Itobttrl tlcckol  (« CI(
t-Prapanol. 2-ntkrl-  (9 CIJ
   7*. 12. BP 107.40 C. TP  10 aa 89  at  21.7 C
iissnz

•055
Breata










•056
Ecaath












ztPosoiE xonz


























1U1RIC11
BZTBCD
oc/as











sons












IDBBEB
or CISKS
8











5* (387
saaplesl












Eiies

lot detect «S-3 1.0 ag/hr











lot glrea












izii 	

10. « ag/hr











0.328 09/1
Seoaetric












Gtllnt IWTCSHtlOt

ccacand related to earaal
xtibotia*. lo otter detail! gireB
CryogeBic flaapliag techBl9ve.

BcaltkT ailltarr a>4 civilian
caeloreea. O.S. llr Force School of
Jcroapace leiiclcv, aoes 23->7 jrt. 3
EtoIierB.
CtlZnZS; CBIOIIIITED BTBBOCISBOS;
cBtopiir* of sine coaponos;
cfiosomzzizs; rnomn COBPOOIDS;
UllTB; I1CC80LS; THIS; 1DTCTS
tcatarel at 25 C aad 760 » 89
13. tl occirreBce
lever aad aff«r oae-sigaa Halts
0.06A and 1.19 ig/1

B«altar, 18-35 rr old, aonsMkivg,
artaa blacks aai Caucasians.
Ckicaqo. 11. SlqldlT cootcollea
•xpariaental eoilitiois.
IltlTI; alCCBOlS; I1UIOIS; « DOLTS;
cnonitTZE insociiBois; >OII*ILI
cieanc coBfcuins: BZUTB BIXUBS;
lIBtliTTCI; ESTtEOLISB: HMIEOLITES;
fCPJUTIOJ IIPOSOW; tJBBU 1BZ1S
SE»B«Z»C«

COBkle, J.p.
Caap, B.J.
Velek. B.C.
1975
IrcLiTes of
far! ronaeutal Health
30 f 2) ; 2*0-295





Krotoazjxaki, B.K.
Bronean, S. B.
C'leill. H.J.
1979
Journal of laalrtical
ToiiiologT 3:225-23*









-------
iiooctrl alcokol  it at
Icooctaaal  (9 CI|
2C*52-21'6
C6-B18-0
«« 130.22
1ISSB1
• 057
Bnatk











EIMSOtS BOOT!













iBaiTtxcja
BETHOO
SC-BS












(OIBZB
or cists
54 [387
suplea)











BUGS
lot given












Bill
1.3 n«/l
SeoMtrie











eiBiBit irroBBinoi
leagued it 25 C and 760 la Bq
1!.IK occurrence
loner and «pper o«-Slq*a limits 0.33
aid 5.1 n«/l

Bealthr. 18-35 rr old. nonanokliq.
urban Hacks ud Caucasians.
Cklcaqo. 11. BlqWlT controlled
EStlTB; UCCEOlSj I1HBOIS: 1DHIT3;
CnOBItllEE BTDBOCtSBOBS; TOL1TXL1
CSGIIIC COSSCTJJB5; BC1LTH HatUtS;
IBBU1TIOB; BETIMIISS; BETlBOltTBS;
PCP811TIOI EIPOSBREt IBBM »EE»S
lERUBCE
Krotanfnskl, B. K,
BrQiiejaii. Gf I.
O'J.ill, B.J.
W79
Journal of analytical
Toxicology 3:225-234







 I*op«itTl «lcohol (B CI)
 1-ettaaol, a-Mtkrl- (» CI|
 113-51-1
 C5-B12-0
 II 88.15, BP -117.2 C. S»  132 C. TP 1 M eg at W.O c
lissnt



•058









'

•05*
areatk













EIIOSOBB BOatl






























aBU/nidl
BWBOD


sc/as











ec-Bs














BOBBSS
OF CUES


8










..
5» (387














B1BGE



Bot detected-2.6 og/ir











Bot firei














Bill



0.3 J9/hr











0.182 aq/1
Geoaetrlc













GEIZBlL ISTOBB1TIOB



Ccatoand related to normal
•etabollsi. lo other detail! tjiren
Ctyoqenic aaaplLno tecnni^ive.

Bealtk7 illltary and clrillan
oployees. 0*3. ale TOEC« Sckool of
l«roapac« Badlciae, ages 23-47 yr. 3
nokera.
IinEBlS; CBlOtlBlTEC BTDSOC1BBOBS;
CtLOHBC 08GUIC COBPOOTOS;
CBLCBOBBftZftS; nnOBKE COBPOOTOSj
HIHB! IICCBOIS; TITaSi IDBITS
Ceamred at 25 c and 760 am Bq
29.11 occurrence
lover and mpper one-si?**. Unite
C.942 aad 0.781 no/1

BealtkT. 18-35 yr old. nonscoklnq.
iclan blacks and caacailana.
Cklcaao. 11. Biqldly controlled
eiperliental conditions.
EB1HH-. alCCBOLS; IUI10IS; 1DOLTS:
CElOBIBltED ByOBOCaBBOIS; TOlltllE
eceinc coBScnrgs: BEJITH mutest
IBHIUTtOt; BETITOLISB; HBTlKltlTBS:
tCPUll'IOi EIPOSOBS: OBB1B atEaS
1
BETESEICZ |
1
1
1
Conkle, a.t. I
Caap, B.J.
Velck, B.C.
1975
arehlrea of
environmental Bealth
30 (2): 290-295





KtotonTBrtl. B.K.
Bronean. G. fl.
0> Belli, B.J.
1979
Joncnal of Inalytlcal
Toxicology 3:225-23*










-------
   1.3->lt*4UM. 2-MtkTl- (9 CI)
  7I-T9-5
  C«-I8
  H Ca.11, IP -1*6.1 C. BP 3* C, T» «00 •• (9 at IS.* C
ussai
aMO
Enatk
«0«1
BTMtk

•062
Brmta
1
1 1
1 1
MPOS01S BOOT!





i ttunxcu
I BTTBOB
OC/IS
«C/BS

GOBS

IDBB»
or CISBS
"


5* (3«7
saaplul

1IIG1
0.09-0. «5 ft*
lot dcteetad- 390.0 »q/ar

lot give*

•Ell
0.23 pp*
129.8 as/he

28.9 *«/!
seoaetric

GBIIUI xiroiBATioi
correct* 9 for level IB Uktl«4 »ir
Maltkr adalts
S1EIEC IDUIISJ BEaSminBT BREO9S:
CCBpovBd c«lat«4 to BorBal
CiTO9«Bie aaBpliaq toekniopa*.
a«althr allitarr ui ciflllan
•iploy***. D.S. lie force Sclool of
•BO tor*.
t Hints: cBioamtio BTDROCIBBOIS:
CROim OISIiTC OOIPOnOS;
CBicsoniiiirs; niioim CORPOVIDS;
ElflXB; 1ICCBOIS: IEHS; ICOTTS
t«*nr*9 «t 25 C and 760 IB Bq
7Qt occnrccnoa
Ioi«r aad apper oo«-Si9»« Halt* 1*.*
ia< 58.3 na/1
Hcaltar, 18-35 yr old, nooaaoklair,
trtaa klBClta and eaieaaitaa.
ckleaga, 11. (laidlr coBtrollvd
»tHH: Hcciots; iiLiwis: iDOt-s:
CBtOBtfHR) nOtOCllBOBS; TOIITIIE
cm tic coetcnns; BIUTB Bizurs;
IIIIIITtCI; KRABOtlSI; BR1BOLIT5S;
fOIOllTIO* EIPOSOBI; U»Ba» 1BB1S
nrsiEic:
jam»OB. B.O.
1969
Joarnal of laboratori
tad Clinical Hetaoi*
74 »«> : 9«l-96«
Cookie, J.P.
caap, B.J.
»975 *
irehirea of
tBTlronaental Bealtk
30f«;290-»S

ttotaaziulii, B.E.
O'Jeill', B!J!
1»7»
Joiraal of laaljtlcal
ToTicologr 3:225-23*
1
                                                                                                                                                                                          CT-
          alcohol (8  CD
S-Propaaol (t CI)
C3-H-0
it «o.o9,  BP -ee.s to -ss.s  C.BP eo.3 c,  t?
                                              M e« at z.« c
TISS9S
Bxattk


ixiosni ions



tuiniciL
8RBOD
ec/vs


iraBn
or CASSS
i


tlKK
lot tot«ct*d-1EO.O B«/kE

tim

38.6 ag/kr

JlSt)
6IIIU1 II7OIB1TI01
CCBFoni related to aotaal
aetabolisa. Bo otkar detaila qiT«o
(••ItkT ailltary aal ciilltat

-------
          alcohol f8 CI)
2-Propaaol {» CI)
«7-«3-0
cj-M-0
•I «9.99,  IP  -88.5 to  -89.5 C.BP 80.3 C.  ?P 10 n H« at 2.4 C
IISSO!
4064
Breath












BUOSOII BOOTH













RRHOO
ac-as












IDBBES
or casss
54 (387
saaples)












11KB
lot given












am
a. ess ng/i
eeoMtric












eiinat IIPOBSITIOB
(ea sated at 25 C and 760 •• Bg
22.2V occurrence
lever aad upper oM-Sigaa liaits
0.1 55 aad 2.76 aq/1

Realthv, 11-35 Tt old. nonsmoking.
«zraa blacks and cancasiaas.
Chicago, n. Bigidlr controlled
experiaeatal conditions.
EBCHK; UCOBOLS; IttlnOIS; (DOLTS;
CflOtXa'aTtt BTOBOCIBBOIS; TOttTItB
cismc C05PCU1DS: BBU.TB BIZIBDS:
iiaiUTiot; atriBoiis>i: arTSBOLiris;
•OC011TIO* BnOSOK; «SBM IBIaS
BHBSBICI
	
Krotosxynski, B. K.
Branean, 6.B.
O'Veill, H.J.
1979
Journal of analytical
toxicologr 3:225-234








 lactic  tcU, batrl ««t«r  (S CI)
 ttenanalc acU. 2-kydroxr-. batjl ««t«r (9 CI)
 138-22-7
 Cl-BU-03
 IB 1U.18,  n  -»3 C,  BP  188 C.  TF 0.» na 84  at 20 C
tlSSQl

»0€S
Br«4th










BIPOSOS! B001E













alllRICU.
acTROg
ec/as











BOBBn
OT C1SBS
8











BUGE

lot detected-3.4 ag/hr











BS*l

0.4 ag/hr











GIIIB1L IIFOBBaTIOB

Ccifoaad related to nornal
aetabolisa. Bo other details qivea
Crrogeaic laapling technique.

Bealthy ailitaCT and civilian
eaplovees, o.s. air force school of
lerospaee Bediciae, ages 23-47 yr. 3
aaokers.
tHIIUS; CBtOBIIHBD HTBBOC1B90HS;
CBLOBTBB OB6IBXC COBPOOUDS*
CB1CBOBBIIIBBS; FIOOBIBX COBPOUBOS;
CBtaTB; alCCBOlS; THIS; atVITS
BETIKEBC1

Conkle, J.P.
Caap, B.J.
Belch, B.E.
1975
Archives of
Bnvironaental Health
30 (2): 290-295






-------
latthaii*
7*39-31-0
la
Ht 138.306, n 920 C. -at 3«» C. TP 3230  » Hg »t  tOO  C,  3*20 « Bg at 760 C
IISSBI


40C6
Bale


















»OS7
(UMT





















«WS
line




















\
EXPOSURE BOOT




































































mtnxcu,
BCTHOD





















tl






















n






















1 OB 8X3
OF cms





















aj 8
b) 20





















a) B
1 9
cj 11




















BIKE






















•1 < 0.06620-0.00040 og/g
b) < 0.00020-0. 0«6 vg/g
•et »t




















I 0.0030-0.01* ogyg
I < 0.00020-0. 051 sg/g
1 < 0. 00070-0.02* og/g
•at vt



















BUI | GEIEXII. nTOMirXOW
1
1
1 t«*i«. 2* cepreaentatin
1 pre-aaalral* treatment* arc
I titillated. The feasibility of a
I holistic, no-«a>h policy tor talc
I malysis is cotliaed and sqpfocted.
1
I mm; TRICE BimiTS; tun;
| USIBII.I1: BIlSOBMBiT RETIODS;
| (ITILS; PSOTIIIS: COBP1B1TITE
| ZTllOitXORS; UIBIBOB; tlTIKXl;
I isswic: Bisins; iioian; CIBSIOT:
1 ciicin«: CBtoBim: cBBOsias: coeiir;
1 ccppti; c«iLHJ!t; eiigiim; GOIS;
I icDin; iBoij iinflMira; LI»:
I B1EKSIRI: IMSIIZSXi HBBCUBt;
I CCIIBIIBOI: IICKILi PBOSPBOB0S:
1 SOIISSHJB; tmiBIVi; SEtEKOM;
| SILICOtl; SHTEB: SODI5B; SIBCITIOB;
I snrn; in: IITIIIDB; tncsm:
I me; ziiccizoa
a) ttot give* 1 a) Coatcol*
b) Sot glTen 1 t) «oc*«rt, qroap* I and II
1
1 t*e*as«a cefinarr and saeltci
1 lectori, age* 55-T< rr, ex posed to
1 *«a»y Mtals 1-3 decades. Time
I t«tnea cetlteaent ani deatk 0-1.5 IT
( ia groif I a*d 2-19 rr, qro«r !!•
I CQotcoli, aa«a *3*72 rr, »io llTed 50
1 t> tco* tkc factory, snedan.
1
1 stinx; cin»»EES: Kioms: iiTii;
i miss: cofpnirtrs mmTiois;
1 IBDOSTJIll BtGXtHi TO1SOBMWT
I iMBOBS: aiTiiofi: IBSEHC; CIDIIBB;
I CIST9B; CBTCBIVII; COI1LI; COPPBS;
i eott; iBof; t.naiitiB: I!»D;
I «lI5HISf: gfSCIIBT: BOlTBOEWni;
1 IEOSPBOB5S: BOBtKoa: scaioira:
I SHZIIOl: SltfEB; TI«; TtJISSIII;
I IIITC: SUITS B121RBS; UDOSTBIII
I FURS; smnnsj tainaioa
1
> O.OOSO ag/g I a) Coatrol
) 4.00SI ilg/g 1 b| locker «ceap I
t 0.00*2 »g/g | c) Bortec groap II
at vt 1
e4iaa* 1 t«c«aa«S ref iiecy aaA SMltac
I vockacSp avel SS-T6 Tt« «zposvd to
1 teary aatals 1-3 4«ca4«3. file
1 tatMea cctlcaMit and deat* 0-1.5 yr
1 In qtoip I aid 2-19 TC, ocoap II.
t ccatrola, *q«« 13-72 rr. vfeo llwd SO
1 ki fro* t>« tactory. S««daa.
1 SlltW; OB1TKBS; KIDtEIS; U?S1;
I imas: CO»»ITITE IT»II;ITIO«S:
i ncos«iit item:; «stsng«nT
1 fiTWis; UTisom: IBS me: cisnaa;
1 CtSIflU: CBBOSIHB; COBkLI; COPVSt;
1 SCICJ ItOI; IlITBtlOII; llllj
1 IIICallSE: BIBCUBt: SOLTBDIIUS;
1 ItOSfBOtOS; (OBIITQRS SCiiOIM;
1 sutiimi: siitii; TIB; KHQSTEI;
1 I11C; 1C1H1 Bktaags; IIDOSTSIU
I mnst s»EiTE«s: TBLLTOID^
l
lEFESBllCE


Chlttleborongh, •;.
1980
Sclaica of the Total
EOTiconaeot 1«s53-7S
















Dcnoe, D.
I>ecdbec9, s.
Hester, P.O.
1980
Science of tie Total
EBTlcoaawBt 1«: 13-35

















Brnne, D.
lordberg, e.
Vester, P.O.
1930
Science of the Total
Eavlronaeat 16:13-35

















(•in net)
                                                                                                                                                                                         00

-------
ll
It* 139.906. » 920 C, BP 3*S« C, TP 3230 M Hj at «00 C,  3*20 m Sg at 760 C
                                                                                      (COITimO)
H3SH
«oc*
tang



















EICOSOIE BODTE





















Hitmen
BETEOO
Ba




















OF C1SES
a) 8
bl 9
cj 10


















BIKE
a) 0.00030-0.023 ng/g
b) 0.00030-0.17 ng/g
c| 0.0010-0.025 og/g
let *t

















BE1I
a) 0.00*0 aj/g
b) 0.011 ng/g
c) 0.011 ng/g
let vt
tedians
















GJIIBJll IIFOB1UTICI
a) Control
b) Sorter qccnp I
c) locker grenp II

Ceceaset ceflnecy aad sneltec
rackers, ages 5S-76 jt, exposed to
k«a*r aetals 1-3 decades. Tine
t«t«een letlceient and deatk 0-1.5 vr
it groan I and 2-19 TC, gcoop II.
Centrals, ages «3-72 TC, vko lived SO
*« ftoa tke factorr. Sveden.
SIEBEI; CID1TEES; KIBIEtS; LITI3;
ITTI6S; CORPlBlTXtB BT» LUITIOJ5;
BITBODS; 11TUOMI:' IBSHJIC; CIDSIOH ;
CEsnm: CBBOIIOB; COBILT; COFPEB;
GCID; noi; IlITBalUB; LEU;
!1I611ESI; RtSCOBt; HOLTBDIIOB;
tsospaoBus: praiDiut; SCIBHTOB:
sitEiiiTB: sum: til: TOIGSISI;
JliC: BialTB B1Z1BDS: lEIDSIBIal
tlins; SIEITERS; TEIIOSIDB
ESniEICE
Bctne, D.
loclbecg, G.
tester, P.O.
1980
Science' of the Total
EaTicoanent 16:13-35















 I lot given















(IEXT
8EaB I
I
») 28. » + oc - 7.6
iq/W nl
b) 27.* * oc - 8.1
aq/100 al
c) 30.0 * oc - 9.*
aq/100 il
d) 27.1 * oc - 7.*
ag/100 al











P«GE|
eilRlL IIPOBBITICS |
1
a) CIS stlftcaa
t) M CIS ayiptoas
c) SI araptoas
d) Gl aynptoaa
significant eoccelatlon p < 0.00003
1« snblects «ith CIS syapteM and p <
0.02 la safctects «ltk GI sTaTtoas.

Be* Tort CltT telephone cable
jplicers, eiclored S oc aore TT.
Ciec SOt vece <30 TC olJ.

l«acological and gastrointestinal
•Ifftoaa.
Ilevated ztnc protoporphyrin levels.
till POISOIIIG; KDOS1BIU POLLHTIOI;
IIDOSTBIII I1DICIIE: LI1D; K« TOEIC;
irmiS; CEITBal BEKVOOS STSTEIt
tIStlStS; IIIOSTIIaL DISUSES; BLOOD

BEFIBEBCE
riskbeln. 1.
Tkocaton. J.
Bloaberg, B.E.
Bernstein, J.
TalcUlias. I.
Hoses, fl.
1>arldo«, B.
Balkriskena, E.
Sicota. H.
Sellkoff, I.J.
1980
laerican Joacnal of
Pablic Health
7 0(7|:« J7-700







-------
lead
1429-M-1
ft
atl 207.2. » 327.4 C,  BP 17*0 C, vp 1.77 SB Bg at 1000 C. 1 •• Bg at 970 C, 10 u 89 at 1160 C
                                                                                     (COirilOED)
T.XSSBB



*071
Blood






























«072
Blood












4073
ood


















BXPOSOBB BOO



iBhalatiOB













































halatios



















IIIITTXCIL
•IT BOD


US































us













s



















IOBEJS
OF CaSSS


160































«













32
It


















BUGS



a) 16-2.0 eg/dl
b) lot given
c) lot given
d) lot given




























) 18-36 «g/dl
) 18-32 ug/dl
) 48-90 ag/dl
) 40-90 ug/dl










lot given
lot gives


















Hal I 6EIIUL liFolaaTloi
1
I
1
a) lot given 1 a) sorters IB saelters and cieiicals
b) 41. « ag/dl | flaat
c) 82.6 ag/dl | t) Cffice aad laboratory workers IB
d) 87.2 ag/dl | 1» «Mlt«r
I c) Prodactica worker la Tl >B«ltec
1 d) Cl«aa up aad Baiat«aaac« vorkers
I la Tl sa«ltec
1 loaitiTe correlation Titi daratlon of
| «aplOTB6Bt.
1
j loilnca ia secondary lead (Belter,
j leaphla, Tl, la scrap aaelter. Salt
| lake City, IT, aad at 2 lead
j cfe«Blcals factories, Joplia, BO.
1
j Clialcal evidence of toxic ezpoavre
j la 70 (ockeis: fatiqae, colic.
j gastrointestinal srBFtOBS, anorerla.
j afalgia, joiat pain, objectire
j treaor, eitansor sascle veakaess.
1 possible eacepaalopathy, aaeaia. lo
1 toiicity detected at < 40 og/dl.
1
| Vl€v«ted blocd Bcea altro^ea, cednced
1 c teat lain* clearaace, decreased ranal
j COBC«B testing abllltr.
1
| ItlD POISOIIIG; IBDHSTBIIL FCLLVTIOI;
| SBtltBBS; IICISTBI1I IEDICIK; IBID;
| BISSOUBI; TtlBBSSn; OTiH; 1DOLISJ
| tlOOO; BIOlCCVBOXaTIOB
1
1
a) 28 og/dl 1 a) Coatrola, boys
b) 20 ag/dl 1 b) Controls, girls
) 68 ag/dl 1 c| Bora
) 63 ag/dl 1 d) Girls
edians 1
| ?«tlent3, aaes 1-3 yr. 85% black, 10V
| Blspaalc, S* vnlta
r
j iBcream in systolic pressarc vita
j concentrations of > 40 ug/dl.
1
| CeltOlM; BYPEBTEISIOS; BLOOt
I IIESSBK!: 1EIO: BPTILS
1
S3 * or - 16 1 •> (orkers, exposed 2-37 souths (Bean
g/100 al j 12.9 aantks) , average workday 11.5
11 * or - 4 ag/109 1 tr, average work days 28.S/»onth
1 t) Costrals
1
1 Bale BD, ia aine corkers, Raraorilik,
1 ages 23-46 hr, e«aa kt 1.76 s, eeaa
1 wt 76 kg. Ccatcols, 4 office workers
1 at aiae, 10 ttaiTersity students, ages
I 23-42 yr. Bean ht 1.7S B aad aean wt
1 7« kg.
I lo observed decrease of aotor aerwe
1 ccadaction velocity of the alaar
1 aerwe.
1
| tllHlBK; ISO ITS; LZID POISCIIIG;
I IITTOVS STSTIB BISHS!S; BLOCD:
1 [IClCCHnllTIOI; IIDHSTBI1L
| ECLH1TTOI; llaD
1-
Esratncc



Baker, B.L. , Jr.
laadrlgan, P.J.
Barbonr, I.G.
Cox, D.B.
Folland, D.S.
Ligo, B.I.
Throckaorton, J.
1»7»
British Joarnal of
Industrial Rediciae
36:314-322





















Jhayeri, B.C.
Lavorgaa, L.
Dube, S.K.
Glass, t.
(Than, F.
E*aas, H.I.
197»
pediatrics
63(4):674-676





PaalST. P. -I.
Sry, C.
Dossiag, 1.
1979
International archives
of Occupational and
tBTlronaeBtal Health
43:37-43












                                                                                                                                                                                          -J
                                                                                                                                                                                          o
                                                                                   (BUT Past)

-------
7*39-92-1
ft
Itt TOT.2.
           BI 327.«  C.  BP t7M C.
1.77 M f« «t TOGO C, 1 •• Bg at 970 C, tO •• Mg at I ISO C
                                                (commit)
HSSUB



»07«
Blood









075












*076
Blood

















BOT7
Blood










rostriB HBTB



aalatloa









BgestiOB











































1IUTTICU
UTBUU


US









us












us


















us











•VB8EB 1 UIS8
or cuss i
i
t
1 I 40-3*0 Be/l
1
|

1

1
1
|
1

55 1 a) lot «ITCB
1 b) lot give*
I c) lot gives
I d) lot give*
I •) lot gl»«»
1 f) lot gl?»
1
I
1
I
1

I
I
1
i
I
99 | a) lot gl»e«
1 b) lot givn
1 cl lot giT«B
1 d) lot glni
I a) lot glf«B
1 f) lot gl*ea
1
I

t

1
1

1
1

1
t
1
IS I B) 3.1-13.1 aaol/1
I b) «.2-1).t eaol/1
1
1
I
I
I

1
1
1
1
m* i ecnuL urouuxoi
1
«
1
lot flliw 1 tatlaatai frcB qrapk. Direct
I dotenlaatloe a»l •stractloa
•
I letters, garage pereoBnol aid potty
1 lockers IB Svedlsh atrplaao factory.
1
| lIDBSTVIlt ICUBTIOI: COBMIMXTI
i ininitioirs: caDH0i: SIEDEI; IOOITS-.
| BIOOT; nilt; BIOlCCniOlJlTIOl
1
1
1 22.9 og/100 il 1 B) !«•• < 21 It. wpoicd
i 32.7 o«/100 al 1 b) loos 50-61 ii, oraoaod
i 37.2 ««/100 Bl 1 c) l«o* 70 aa4 em, exposed
I 19.1 19^100 al I A) >o*« 20-29 rr. eomtrols
1 20.B if/100 al 1 •) lg«* 5D-6« rr. eoatrols
1 17.3 oq/100 Bl 1 C) « 10.93 ag/100 el 1 laterclaeq*. saloa
e) 1*.93 og/100 al | el 17 so after opeelag of
n 19.21 vg/100 al I litereaaaoe. Bales
I df Before opaninc of isteccaanqe.
1 teaalea
1 e] 5-9 BO alter apeBiag of
j iatareaaeqe, feaalea
1 t| 17 BO after opeaiag of
| intereaaaqe. feeales
1
I tesideat* eitklB MO • of Uoavar
1 laterekaaqe tm tke V.C.
1
| QltYBO VII60CB.; BIOQO) UiO; BEtklSl
| lOTOHOTm
1
1
at lot give* 1 a) 3-11 jr eiposar*
bt lot gl
-------
lead
7*34-42-1
Ft
«tt 207.2. IP 327.4 C, BP 1740 C. TP 1.77 11 Hg at  1000 C.  1  •• Hg at 970 C.  10 11 Rg at 1160 C
                                                                                      (COITXIOED)
TISSSE

4078
Blood












4079
Blood













4080
Blood













1081
Blood
















EIPOSORB ROOT













































ngestlon
nhalation
















iiaimcu
BETH 00





























IIS
































101 BES
or cisss














110














a) 56
b) 70
c) 50
d) 69











40

















BIKE

a) lot given
b) lot given
e) lot given
d) lot given










a) lot given
b) lot given
c) lot given
d) lot given
e) lot given










a) 15.1-20. t ag/100 nl
b) 11.8-14.9 ag/100 nl
c) 10.4-11.1 ag/100 nl
d) 8.0-9.6 ag/100 nl











lot given
lot given
lot given
lot given














Bill | GEIEBAL IITCBH1TIOB
1
a) 32.5 og/100 nl | a) Blacks, Jane. 1970 and 1971
b) 21 ag/100 nl I b) Blacks, Bee-larch, 1976
c) 23 ag/100 nl 1 c) lispaaics, Jane 1970
d) 18 ag/100 nl I d) Rlspanica. March 197C
I Geonetric neaas. valnes estinated
1 frcn graph. Seasonal pattern.
I decreasing trend froa 1970-1976.
j levels correlated with gasoline Pb
1
I JE-36 so olds, lew Tork city
I it* tost; eaiLDRii: item STUDIES;
I BLOOD: COBPlBlTIfE ETALOATIOIS: LEAD
I BITALS; ADTOBOTIVE; POPOLAIIO*
| tlPOSUBE
1
a) 55.8 * or - 9.7 I a) 58 aonsnokers
ag/dl | b) 23 snokers, < 1 pack/day
b) 57.7 + or - 13.7 I c) 29 saokers, > or « 1 pack/day
ag/dl | d) siokers, high exposare (860 og/cu
c) 60.9 * or - 12. 1 | n)
ig/dl | e) KoBsnokers. high expasare (860
d) 64.4 « or - 11.8 | ng/ea it
ag/dl |
e) 57.8 + or - 10.8 I Sielter workers, average age 40.8 *
ag/dl j or - 8.2 yr. Los Angeles*
| CILirOBHIA; BLOOD; IBID: RETA1S;
| CCC071TIOIAL RAK1BDS; POPOL1TIO1
| ZIPOSVB^; SKELTERS; SROKIIG
1
1
a) 17.2 ag/100 si | a) Bales, Los Ingeles
b) 12.8 ag/100 nl I t) Feiales, IDS Angeles
c) 10.8 ag/100 nl | c) Hales, Lancaster
d) 8.8 ag/100 nl I d) Feiales, Lancaster
Geonetric neaas j Areas differed p«.001
1
| PITALS: PLITIIUB; PALL-ADIOfl; HID;
1 ECEOIITIO* inOSORE; OOCDFltlOIAL
I BIZAP.CS; CA1IFOEIIA; AOTOPSIIS;
I eiocD; xiDiETs; SPLEES; BAIR; OSIIE;
| I DIGS; BVSCLF.S; ADIPOSE TISSOS:
| IITBS; COHPABATITE ETALOATIOBS; III
| JtSSEI; CII1DA; HtlllS; A0TOnOTITE
1
1
1 16 ag/100 nl I a) Start of enploynent. no previons
1 55 ng/100 il | occupational exposare
I 78 ag/100 nl | I) 10-12 wk after enploynent
59 ag/100 nl 1 c) Siplayees relayed fron workplace
1 luring study, at tiae>of rencval
1 d) Enployees cenoved fron workplace
1 daring stady, 16-18 vk after renoval
I Considerable difference in rate of
I change and tlateaa state for Pb and
j la protoperthyrin
1
1 lead snelter workers
I A cons : BLOOD; ERTTHBOCTTES:
| IICOSTBUL BTSIEIl; LEAD: IIIC
I OfiAITC COSPOniDS; IIDOSTRI1I
| MROSPRE1ES; IWBALATIOI; SRFXTERS;
| CCCUPATIOIAl BtZARDS; CORPtBHIT?,
1
RE'EEBICE

Billlck. I. 8.
Cnrran, A.S.
Shier. D.I.
1980
Environmental Health
Perspectives 34:213-217








Brown, C. P.
Spivey, G.H.
Valentine. J.I.
Browdy, B.L.
1980
Journal of Toxicology
and Environmental
Health 6:877-883







Johnson, D.E.
Prevost, R.J.
Tillery. J.B.
Caeann, D.E.
Rosenfeld, J.B.
1976
EPA-600/1-7S-019, 235
PP.







Besley, K.I.
filbish, G.B.
981
Journal of the American
ndastrial Hygiene
ssoclation 42:42-46












                                                                                                                                                                                          N3
                                                                                    (IttI PIGI)

-------
lead
M39-93-1
n
lt» 207.2,  II 327.*  C.  8P 17*0 C. TP 1.T7 » Bo at 1000 C, 1 •• Eg at 970 C,  10 M Ba at 1I«0 C
                                                                                     icawnmrn
tlSSOS
«0*2
Blood








•oej
Blood












• 08*
Blood














4085
Hood






•OBS
Blood











IFOSOU XOtJII























lakalation






















Ingest ion











ifUTflcit
BRBOD
tttUTone








US













us














us



















mat SB
OF CISBS
13








1













a) 18
b) 12














100







1











IMSf
lot given
lot given








1 3.7-9.* QBole/1













a> lot given
b) lot giv«n














1.0-13.0 «g/108 Bl







a) lot applicable
b) Ml applicable











Bill «1IESU. IHFOIMTIOB
) 60 » or - 15 •> Batter? factory vorxers, expostra
gylOO al 1 6 ao-33 jc
1 2» » or - 1* | b] Controls
9/100 al |
1 lever eotor nerve conduction
1 velocities it exposed vorkets
I HID; T5T1LS; BLOOD; DdTED KHGMB;
| imOBS SY.S1U DISSISSS; OCCOP1TXOIIL
| BIMBOS; IIDTJSTBII1 FLIRTS
1
a) 5.1 asole/1 | rt-poi««ned cases
1
I 18-56 vr olda, iaiastrlal exposures.
1
I Ikooaiaal crasns, coastlpatica.
1 veiitiag. fatigue
1
I llll; IBID POI30H1G; iroosTBIU
1 tisiisis; HDdSTiin pcunnci;
| H100B; C1SI tKTOEItS; IOTOPSIBS;
1 tun: iiBitis; RITES: BSIII; iins;
I Bin; iivn.; sons: OTXTXD nisooi;
1 icutTS; SMITH Biziaas
i
a) 12.0 » or - 9.6 I *) Oeenpationallv exposed
nq/100 el | 11 controls
b) 27.8 « or - *.• |
aq/100 el i 27-50 Tr olds, in storage battery
I lannlacticlag plant. J8-»8 it old
j ccatrols.
1
I Iicreaaed rates of abaormal
I sttaphases vith ckronatid aberrations
1 in vitro.
1
1 HID; "Brits; CHWHOsoau
1 itinmoBs; ITU.T: HOOD; HEII.IH
| RlZtBDSs IVDHSTBZUi PLAVT5 !
I CCC««HIO«l BKI1DS; TOSUHT1O1
I iinsoiE; it vino miTsis
I
S.2 » or - 2.5 soyiOO | values lower than generally nported.
al | Ineiaved, contani»ation-free aanpliag
1 t«c»»lqn« aad cheaical analysis
1 Tcoible factors.
I
I 7-10 vr old ehlldres. reaote area of
I faBia lev Guinea
1
I eicco: me: anus: catmBEi; IE*
i eoiiu; mill ISMS
a) 112 ng/dl I a) Ca adalsslon
b) *7 ag/dl | t) 1 no after chelation therapy
1
1 23 yr old Japanese palater.
1
1 racial pallet, aild 1amdl.ce,
1 arioelaal colic
1
I iBcala, tiqh levels of arinary
1 Iclta-aaiaolevQllaic acid and
1 coiioporplvria.
I ElOOO; Kit; LE1D POISOIIIG: BITllS;
1 Jini: puns: occvpitioiii BIZUIS
1
(I SIT PISH
antatcs
IcnbT, J.a.S.
1980
British Javn&l of
laa.strinl Bediclae
37:133-1*0





Caapbell. B.C.
Seattle, I.D.
Elliott, E.I.
SoldberQ, 1.
Booce, B. t.
Beevera, D.6.
Tree, R.

Archives of
Environaental Bealth
3*(»);«39-««J



roral, I.
Sciaee, i.
BertaiTi, J.I.
lleasio, L.

Irchives of
Inviionnental Bealth
35(3) : 139-1*6








Pool*, C.
SBythe, I.E.
llpers, a.
1980
Science of the Total
Eavlroneeat 15:17-2*




Cblba, a.
Toyoda. T.
Inaba. I.
Ogikara, K.
Kicvchi, B.
1980
lev Saglaad Joaraal of
Aellci ne 303 (8> : *59







-------
lead
7U9-42-1
«
lt« 207.2. If 327.* C,  BP 1T*0 C. v» 1.7T •• Bg »t 1000 C, 1 •• eg at 970 C, 10 mm Bg at  11«0 C
                                                                                     fCOITXIOBD)
MSS0E
• 087
Blood
•088
Iloo4
1089
Blood
«090
ElOOl
»posm not
Ingestion
Xngestion
Insolation
Ingmtios
Inkalatlcm
iBgeatloa
Inaalatioa
aiaiTTicu
HBTHOD
Isotope dilation

IIS

TO BBSS
or CISES
s
12
124
7
11IGB
0.15-0.33 ng/g
3.31-3. (6 miol/1
100-370 09/1
) 38->120 ng/100 •!
) 90-120 09/100 ml
) 66-97 ug/100 il
) 61-102 ng/100 ml
) 57-61 ag/100 ll
IBll | 6B*ml nrOBIHIOl
|
lot given | lefore and after 1*2-215 ng/day
1 («icl»
-------
laad
7*39-92-1
ft
ItB 207.2,  Bt 327.* C, BP 17*0 C. TP 1.77 » Bg at  1000 C,  1  •• Bg at 970 C.  10 an Bg at 11CO C
                                                                                      (COITIBHID)
1ISSBJ
«0»1
Blood
•092
Blood
» 093
Blood
IPOSOSB iOWB
ngeation

Ingestion
Inhalation
IBliniCll
8 IT BOO

1ST
US
BUB MB
or cisss
38
38
w
19
) 19
) 28
371
MKS
Bot gin*
Bot givea
Bot givea
Bot givea
) 11-58 «g/dl
) 11-126 09/41
a) Sot givea
b) Bot glv«n
c) Bot given
d) Bot given
o) Bot glvea
BI1B | GSBBBU IBPOBB1TIOB I 8IHEHCI
I 1
1 1
1 1
1 1.91 * or - 0.66 | •) (others IB h oases »ith lead cipes I flvood, J.C.
aol/1 1 *1 Children !• houses vita lead pipes I Thoaas, B.
) 2.01 * ot - 0.63 I c) Bothers la houses with copper 1 Sheltany. R.
•ol/l I tlpes 1 1978
I 0.67 » or - 0.23 1 d) Chillrsn In houses «lth ccpper I lancet
aoVl 1 tipes 1 1(80781:1363-136*
) 0.93 * or - 0.81 1 1
aol/1 1 Bcther-ano-child pairs living la I
1 north valos d«r«lopBO&ts I
I IIV1TS: CBI1DSII; BLOOD: COBMB1TITS I
I iiiinnioBS: IEID: BIO»CCOBOI»IIO«: i
I BBIBKII5 »»TIB |
1 1
a) 16 ag/dl 1 a) Controls | Haaaoad, P.B.
b) 91 ag/dl I t) secoadarT lead saelter vorkaia I Leracc, S.I.
1 1 Gartsld*. P.S.
j 19-C* Tr old «ork*ra, 21-63 TC old I Bananson, I.E.
1 coatrols. I Boda* S.B.
1 1 Tonltes. I.e.
1 lettma reported 10» Incidents of I Johnson, 0.:.
1 aaurologlcal, gastrointestinal or 1 Pesce, l.J.
| ether aTBBtoaa. controls recocted 2* I 1980
| aach lacldeats. 1 Jonrnal of Occupational
| ' I Dedlclae 22 (7) :«75-»8«
I ElOOB: IBID; BIOIIBICITOBS: 1
| IBCDSTtlll ellRTS; 1IDOSTBI11 1
| PCIITTTOI; SBELTBHS; HBUTB EIZISDS; |
| CCCDPHTIOmi BlIIBOS: |
j ClSTBOIBTBSTniL STSTSB; BBOBOLOGIC |
| H1IPEST1TIOIS |
1 1
1 1
a) 0.11 Bg t | a) treated encepfcalopathy patleats I albert, B.B.
b) 0.08 ag * | c) Treated Pr-polsoalag patieats | Shore. B.B.
c) 0.07 Bg * |c) Untreated sablects ultfc hlqh I Sayera, l.J.
1) 0.0* ag 5 I Hood, aloh ec In tooth Pb lerels I Strahlo*, c.
e) 0.0* ag * I a) Vatreated sab-teets tilth lo« blood, | Inelp, l.J.
Mdlaas I Hqh tooth PC levels | Pastecnack, 3.5.
I «) Untreated sabjects «lth 1m blood, I Tcledhoff. l.J.
| lev tooth Pb levels 1 Coras, F.
1 I Clalao, J.l.
I Chi Urea In Pb register of BI City, 1 197a
1 iitlinqs of ceqlstcy cases and dental I Invironnental Health
I clinic patients. Host «ere tlacX, 1 Perspectives 7:33-39
( Cccn lo*-lnccne fanilies, ages 5-15 |
1 yi, n«a< 2.3 yr. I
t 1
1 liqk incidence of psychological I
1 referrals and behavior pcoblena in I
1 a) , b) , c) . Convnlsioas in « j
j catieats. a of 6 encephnlopathy j
1 patients nentally retarded, aoae j
j diagacsed organic brain syndrone or 1
I aeizare disccders. |
1 1
1 II1B; 1R11S: CHILDREB; IIB |
| FOIHRTOB; BfB TO8K; SIT1L PCISOBIWC; |
| KB1VIOB DISCSOBBS; BSTIBDITIOI; I
| E10CD; TEETH; P1IBTS I
1 1
                                                                                         (IEII  PIGS)

-------
lead
It
lt» 207.2, If 32).* C. 8P  17*0 C, TP 1.17 aa Hg at  1000  C,  1 Ba 19 at 9TQ C, 10 u I 20
4 122
t TO
1 60
»
MICE
«) «-11 B«f
k) 7-M 1191
c] 4C-64 agf
4) 37-S« B4*
») 3-2* og/IW Bl
b| 7-19 ag/lOO ml
c) 6-20 og/100 ml
4) 5-37 09/100 si
) 7.0-26.5 ng/100 »1
1 2.3-37.1 ng/IOO el
7-».0 aaalA?
MM i enttit, xiroiaiTioi t tsnREicE
1 1
i i
a) 9 » or - 1 mgl I •) Control* t Baoharaa, S.8.T.
b) 1» * or - 3 BO* | n irposea. M tmleltr | c«l»«, S.D.
O S« » or - 3 >4« I e| Erpomd. «r«Pt<»«tic ai< 1 Sonic*, B.C.
4) »5 t or - • igX | tlock«ie*l ii | liTlroBMntal S»a«rch
I teiiedtT I 22:2«»-270
I tc*Unal rb (sac •!>« Pb la I
I kmogloblB tiaetim. 10,000 n I
1 ttactloa, »mt tt»» d» |
1 1
1 m-»po»d ladacUlal *ork*», *g« I
1 25-«5 TT. tipaacd workers tro» Pb j
1 inltlni pl««t. |
1 »ems«4 rlak of -toxlelty *t lo« 1
1 blood Pb l«*«ls IB MTlwr* vitfc I
1 4l«i»lslL«4 caoacltl tot sntkuixlaq t
I lev »lxc«lar «t Nt-Undin? protsio. I
1 t
1 ICOITS: U1D POISOIIKi BIOOI; |
1 mosrnu einicift: ntsgtiRit r
i CRICK; tint ineatsia. nam i
1 CCCDPIIIOIH 81Z1BB3 |
1 1
1 t
a] 10. S « or - 3.7 | a) ratiats. 8«lb1 | Cbildna'a BoipltU I DoiBaa, H.B.
bl 11.1 « or - 3.0 t *>> Sekool ckildna, B«lbo«ra«, IBB« I 1>80
•4/190 B! | utocn | B.dical Jonnal of
c| 11.* + or - 3.5 | e) Scaool children. St. Jtadrns, I listralla 2{C) :315-3t«
•«/100 al 1 Mai-c««l »t«« [
i] 13.3 * or - S.5 Id) rrt*CBool cttUraa, lelboora*. I
oq/100 B! 1 laa«r snbnrtg |
1 TCBOa* SBBfllS i
I IKvated Pb <> 25 aq/al| In 10< of |
1 Mlnoan* Fnschoalani if from pica. I
1 Era-school a»d •ekool-aoe c»ildr»B, I
1 StaU ot Tletocla, lB«tcalla I
( lOSTdlll; CniDEM; BLOOD; lltU; |
i Jioiccammoi; nsn utts; amis i
i i
I i
1 15.1 * or - 0.59 1 a) Controls ( lta*«cjs. 8.
4/140 ml 1 t) tasidaxta ot point »4 area 1 Foals, 1.
) 1«.« « or - 0.90 I | Bernard, a.
4/110 Bl 1 lean, ««an a«e (2.3 Tr, froa 1 Bacbet, J.p.
S.S.) 1 Cd-pollated area ni*4«>. tit 1 1»40
1 controls, »an aoe »1. 1 jrr, troa 1 International Ucblvas
1 ckatlarol. Ealqina. 1 of Occupational and
1 1 SaTlroBBeBtal BJealtb,
1 BLOOD; BLOOr PLtSSt; ISItti C1DSIM; [ (5:271-27*
I Hip; XSSCVI1: ItKl SIHMS; SEtSIfff; I
I let: KPotiTtoi sxposoiE; UDOSTEIH i
1 ICtWtlOl: SBBlTEtS; KIDVEI tISHSIS I
1 •
1 1
3 aaolAg 1 l*ad polsoiieq casea ! Iraki, s.
edlan I I Banna, T.
1 24-59 rr old Japanese lead «orke» 1 Tanaglaara, 5.
1 1 oaxlo. I.
1 f«riptetal narre coa8»ctioi wlocilj I 1980
I I8C*| cornlatel vltt Blood Pb. BCT I International Icealrea
I laproreaeBt after caelatioB IherapT. I cf Occupational and
I I ZBTlronBeatal Maltb
I 1110; B1OCO; POP01AWOS EIPOSTSt; 1 ««: 151-157
t CCCVPKIOIII tatnos: IBOBCICCIC i
1 fllHIESflTICU; aiTllS; LEIS t
1 PC1S01I16 |
1 1
tlttt f kGt) ' '

-------
ft
Jtl 207.2, RF 327.* C, BF 17*0 C, TP  1.77 u  Bg at 1000 C. 1 » Vg at 970 C. tO •• Hg  at  1160 C
                                                                                       (COITIBVED)
nssvs
»098
Blood
(099
Hood
4100
Blool
1101
Blood
• 102
Blood
IfOSOBS IOOTI
ngestios:
Ingestion
Inhalation


iiiimcii
BBTBOD
ix
BS
US
us
1ST
•OBBEB
OF CUSS
00
) 5
) 1
a) 60
b) «
cl 70
a) 32
b) 7
a) 22
b) 22
c) 10
11KB
or - 60 09/100 al
) 0.17-0.25 09/9
) 13.8-11.3 og/q
a) 2.3-37.1 ng/100 »1
b) 6.2-28.7 ng/190 il
c) 7.0-26.5 ng/100 al
a) 1.0-2.7 uaol/1
b) 0.4-0. 8 uaol/1
a) lot given
b) lot given
' c) lot given
BBiB i entail nroiBiiioi i iBPiBEici
1 1
i i
1 1
ot applicable | feaitlve correlation »Uh 1 roster, J.8.
1 environmental Pb soirees i lonria, D.B.
1 1 Stinson, I.
I 9« black ana 6 Bispanic children I 1*79
I 1 Irchites of
I less of appetite, nausea, I Znvironnental Health
1 constipation, nental retardation I 34(5) : 368-371
1 1
1 Brain damg* 1
1 1
| III jnSIT; CRIID1S1; IBID PCISGlTIG: I
I tIRll SETItClTIOl; HOOD; 1119; )
| BR1LS |
1 1
1 1
) 0.19* ug/g 1 •) 10 and 210 days after tracer doses t Sablaovitz. 9.
) lot applicable I of 68-20* nq/day pins dietary intakes 1 Vetherill. G.
1 of 1*2-215 ng/day as nitrate. j Kopple, J.
1 treathing nn filtered air 80.7* of the 1 1975
I tiM and lead-filtered air 19.31 of 1 Proceedings. University
I tbe tine 1 of aissovri Innaal
I t) 0 and «0 days on air filtered to 1 conference on Trace
1 rcnove Pb. (49 yc old) . Back to 1 Substances in
1 initial level after 20 days breathing 1 InTirouental Health
| »fllter«d air. 1 9:361-368
1 1
I 8«althy 25-53 yr olds in netabolic 1
I vard. lo» Pb diet up to 6 no. 1
1 1
1 Tito: ICTUS; HIIJB&I. mTiioiisfl: i
1 H1I»: FKIS; BLOOD; 118 POIltJTIOI: |
I 01EH UI1S; 1D01TS: C01P1BITITI I
I miomo*s; OISTS i
i i
I I
a) 1>.9 ng/100 al 1 a) Residents of liege (lost polluted I Reels. B.I.
b) 1».« ng/100 nl 1 area! 1 Lanwerys. B.B.
e) 15.1 ng/100 al 1 t) lesidents of Bcassels (leas 1 Sachet. J-P
Seonetrie j tellnted ar«a) I Bernard. 1.
1 c) Control area 1 1981
I R«ans and eunnlative freqaency I Environnental Besearch
1 distribution* not aach different I 2»t 117- 130
I hctveea tbe three groups 1
1 1
1 8«altay snb^ects >60 yr old, I
I residents of the sane areas 25 yr. I
I Belgian 1
1 1
1 SIISIUI; iBDITS; let; BLOOD P11SB1; I
1 Ollit: CICHIHH: LtiO: BISCORI; 1
I BIT1LS; ZTIIC: tRDOSlBIJlL 1HISSIOHS; |
I IllOTtBTM tCL10tIO«: POPOlMIOt 1
I JIPCS08E; OBEII 4SBSS I
1 1
1 1
a) 1.6 anol/1 I a) sorters at Pb line 1 ttansen. J.P.B.
b) 0.7 naol/1 I t) Controls I Dossing. B.
1 fstinated frcn graph 1 Pauley. P.-E.
1 1 1*61
1 Residents cf Greenland. 22-46 yr old. I Journal of Occupational
1 1 Bediclne 23(1):39-«3
1 GBizniii; » COLTS-. BLOOD; OEIII!: t
1 I!«B; OCCUPMIOlkL BlZlSDS; MHHIG |
t t
1 1
a) 2* ag/dl I a) Gout patients, no renal disease, I Batanan, T.
b) 26 ug/dl I 1C had prior Pb exposure I naeeaka. J.K.
c) 26 ug/dl I b) Gout patients, renal disease. 10 I Haddad, B.
1 had prior Pfc exposure | ?epper. E.
1 c) Patients, renal disease, no gout, I landy, E.
1 ne Pb exposure I nedeen. B.P.
1 I 1981
1 32-78 yr old gout patients I Hew England Journal of
1 1 Bedicine SOU (9) : 520- 523
1 IE« JIES;i; » DOLTS; KIDRET DISE1SES; |
1 EtCOD: HBIII; LE1D |
1 1
(•in mot;

-------
lead
7*. 39-92-1
It
It! 207.2. I? 327.* C. BP 17*0  C.  It  1.77 u  Rg »t 1000 C. 1 ll Ig at 970 C, 10 u Bg at  1160 C
                                                                                      (CORHHSO)
TISSUE

«103
BlOOd







*10*
BlOOd






*105
Blood









• 106
Blood,
evils













Bisoson BOW

















lagestioa









Xaaalatloa
Dersal














IBlLRXCat
1 ETHOS








US







us









us















IU1BSS
OF CISSS
•I *8
b» «S







1) 88
b) 11*
C) 31
4) 33





a) 30
b) 20









20















UKE

t) 20-125 09/100 ll
b) 22-80 ag/100 ml







a) lot giv«B
b) lot gi*»
c) lot gi»en
d) lot gi*ea





a) tot gi?«
b) lot giT«n









a) 39-5» ag*
b) 107-150 «gt
c) 172-209 ag*
d> 102-120 ng«












SUB

a) lot giT«i
b) lot gi'ea







a) 180.0 ag/1
b) 268.* og/1
e) 668.3 ng/1
d) 818.1 ag/1





a) 25.* * or - 12/1
ao/109 ll
b) 17.8 « or - «.9
oij/100 al








a) 46 » or - 3 uq«
b> 130 » or - 8 og*
c) 193 * or - 7 ug«
d) 110 * or - 3 og*
(S.8. )











ei»ui irroiaiTioi

a) lortars aipoaad at least 1 re
b) (octors pnTioaslT upoMd > * ji,
>ot exposed (or 12 or »or« » prior
to *t«ir.

it BITS; Biooo: DHR: ma:
CCCOP1IIOIJ1 H1I1BB3



a) Oat»«rsiti atadtnts, esploTeas
t) workers, steel ladistrr
c) lorkers, battery factory
d) lorkers, secoadarr Pb sielter

17-63 yr old Caucasians
caiiBi; loons: BLOOD: SUITI; w
1ITO IULTSIS; HID: NR11S;
OCCtJPlTIOIH BUMDS: SBE1TBJS
a) HeatallT retarded ekildrca
b) Coatrols
Erobablllty ef aeatal retardation
iaereased *h« Pb exceeded 800 vg/1
later.

2-5 yr olds.

me: inns: oiimcHs vim:
cnufsi; ititii BBTUUTioi; BEHTB
CI!»OS

a) Coatrols
t) Bxposed, BO toxtcity
c) Exposed, syaptoaatic and
tiocheaical crid«nc« of toxicity
d) Exposed* syaptoas suggesting
toxicity
Icn-«x!>ose3 industrial vorkers, ages
2!-*S yr. Zxposed vorkers froa Pb
saeltiag plaat.
lacreased risk of toxicity at lov
blood Pb leTels IB workers vltb
lisinished capacity for syBtheslziag
lev solecvlar «t Pb-biadiag protein.
DOITS; HID POISOIIIS: BLOOD;
ivosniti BE0ICIWZ; T.IID-. IIDOSTBUI
I1RS; OCCOPtTIOIlI a»Z«BOS
1EFEIEICB

llessio. I.
Castolli, H.B.
nonelli. o.
Toffoletto, r.
Zoccketti, C.
197»
iBternational ucUves
of Occupational and
EBTlroaaental Health
««:127-132
P'aa, l.T.S.
1981
Joornal of Toxicology
aad laflroBBeBtal
Health 7:273-280




Seattle, ».D.
Hoore, B. B.
Goldberg, 1.
Finlayson. 8.J.W.
Backie, B.a.
Grakaa, J.F.
Bain, J.C.
RcLarea, 0. t.
Rardoek, B. R.
Stewart, G.T.
1975
lancet 1 (7907) s 5 89-592
Bagnavaa, S.B.V.
CalTer, BlD.
Gonick, B.C.
1980
ZoTiroaaental Research
22:2«*-270










(Htt P»SB)
                                                                                                                                                                                             oo

-------
l«aot 9l«*
b) lot gl«B
mi i GIIIIU urotamoi i nnisicz
I i
« i
I i
23*10 ng/100 al I it Coitcol* 1 Taccaro. S.
•8.3 M/100 *1 1 *) OccipatioaallT expoeed te about 1 | Barakigiaii, C.
I ig/cm • list with J.7-12.»» Fk 1 Coloibcttl. 6.
j itTtkroeyt** 1 I*ncl, r.
1 I lol, l.B.
| Itlllil factorr MCk«rsl HMD f PiqqUco, T.I.
| «ipo»»r« tii« of ».« yr I paqxno, 5,
1 j Tola, 8.
| Io4«tmt« to MT«C« litabolic •ffccti 1 1)80
I tm »0t of «ifos«4 «ar1mrs. 1 Iit«r»«tioiwl ircklT«s
j I of Occupation*! and
I IULT; 19tHlS; 1MB !O1SO*II6: BETal I BnlcoBMBtal Health
| TOISOniS; CCCTPitTOKl DISUSES; t »S:35-»«
| ROOD; OIII1; COSMtltlTB |
1 imomois; IIDOSIJIH ncini: i
1 iiisniam nnogs; I.SIDJ units: i
| CIST: HalTB UZ1IDS; I1DOSI1H1 I
) IT90STHIIIS; nilUTIOIi OCCffP»TIOIIl |
I llIMtS |
1 1
I 1
) ««.53 ng/dl 1 a) 111 etlllna I Sos«n, 3.1.
1 7» * or - t (SI) 1 k) 12 ckliaco vitk initial ft levels I CkesMT, ».»•
g/«l | > 60 n/ai I Baistci, k.
1 21 » or - » «St) | c| IV* 12 ekiUrett in b) aft«r I Detuca, B.r.
V41 t ckelitloB tk«npi t Bekatfey, K.I.
I I 1»80
I 1-S it oil*. IT. I lev I»9.1»4 ]o«rul of
1 I «*aici»«
1 »»; TITUII 0; CBIIDNI: in VIE; 1 302(20) :1128-1131
I E10CD; COBMUTITI ITHff»TIO»S: BLOOD I
I SJttJIt! NCtlBCtlSl; RRIBOintS: 1
1 BtnoncnoiiMiciRioLS i
1 1
1 t
166 ug/1 I le*-oce«pitiaullr exvonl. I lTgo»i«, E. B.
1 1 Boll«ba: i 2«(ioiti«i3-i«ia
1 CC«|lt>TXlI nilOKIWIS; KIISDIHSIT I
1 BIHODS; llICi OCCUPUIOVal UCUDS 1
t t
1 1
32* of dose 1 t*ake, aftec -eea* 1«D4 expense* of I Borrow, P.I.
1 130 pq PbClJ u 0.26 n acrogol or | Beltsc, H.
1 11.54 <« fb(C8)2 *• 0.24 « iwoaol. I Into, r.
1 S«ak tlie 2019 «i». IstiMted blood ) Sibt, r.E.
I »cli*e 6f boil «t. 1 1*80
1 1 CBTiraiMititl B«9«atck
I 20-56 Tt old*, SS.0-95.4 kij. Bo 4 21:373-38*
I kl*toCT of talaoiarr tis*»«. j
1 1
| II»D; UKSi COBNtlTITB BTttOaTKIS; I
I HOOD; inumoi: in ?oiimoi: i
1 tMsaumn imoas; IDTITS; m TOBK i
i i
1 l
a) 16 * or - TV | •) S*b1eet* »itk Bocaal re alsocptioa I »at»o», i.s.
t} 47 * or - IK | *aa **»* feiritie. InelB 1 Una*, 1.
1 t) S«b1act* tltb klgk Pe absocptioi I floor*. t.B.
| «»a nbnoiaal aene I«rriti». t 198«
| Significant fosltln eorrelatio* I taacet 2(8188) :23«-237
1 t«t«**> oral Pb aid F« absocption. j
1 35-70 TT old*. Halted Kiaadot. 9 I
1 patients »itk chroalc blood loss, j
j taaipareii*, or TevemctioB tor I
I secoBdarf polfcytkeeia. 1 *CTaal I
j tlcgfl daioc. j
1 (
I oinr? itlisccB; BLOOD SOURJ BOB»: i
1 tlOICCQIWHTIOl; lETIBOLISB; II TITO 1
| III1TSIS: ltd; LHB I
1 <
tun MGQ
                                                                                                                                                                                                v£>

-------
lead
7US-92-1
ft
It? 207.2, ft 327.* C, BP 17«0 C, T?  1.77  aa  Bq at 1000 C. 1 aa 89 at 970 C. 10 mm Hg at  I ISO C
                                                                                      (COItlmtD)
1ISSOI
•112
BOM
• 113
ton*
»m
Ben
«115
Sral*
UPOSOBS TOOII




IBU.TTICU
IZTHOD
US
I-r»r spcctroi
Elec troche •
Elec trochee
WBJJB
OF C1SES
»> «2
b) S3
O 1»
22
1

11IGE
*) 1*>21« PS*
b) 11-13* Fpe
e) 0.3-15 ppa
15t> rt
20-11* lj/9
•) lot «if««
b) lot gi»«n
c) lot git en
) lot oi»«B
lot gl»e«
mi i eiiiBii XMoiBHXoi i tcnmcx
I I
i i
*) 72 * or - 40 ppa 1 •) Black adqlts 1 B»* (27-75 yr oil) at I 1980
I storage battatT plant. I British Journal o*
1 1 Industrial ledlclne
I SIMM: BlOOt; BOtTS; n TITO I 37:109-113
1 1II1TSIS; LI1D: IR1U; IICOETBIil 1
| [HITS; OCCOPITIOMIL MUSDS; |
I PCPSUTIOI 1IPOSBB! |
1 1
1 1
a) 136.05 noyg dry lit I a) lib I Caipbell, B.C.
b) 3T.50 ag/g dry »t 1 t) calraclii { Beattla, l.B.
e) 163.33 ag/g drr "t 1 e> Stera<» I Elliott, S.I.
1 Utopsy saiples f Coldbarg, 1.
1 r Roore, B.S.
1 3« JT alt aetal buraer, ecposel | Bearers, S.S.
1 4«ring a building 4«Mlltloa 3 ao t Tree, H.
t earlier. Killed la industrial I 1479
1 accident. t JrcKiTes ot
1 | ZaTlronaental Health
I Ibdoalaal craapa, coBStipation. | 3» (*) : >39-«»3
1 foaitlng, f»tigne (
1 1
1 1111; KID IOI50III6; IHDtJSTKUl 1
| CISElStSi IIBBSTHll POLLOtlCI; 1
I E10CO: CIS! tlSTOSISS; ITtOPSIIS; |
1 8I1BT: MDins: »ra»B?: aau*: MILS: i
1 BUS! IITEE; BOIES; OIITED KIIGCOS; 1
| 1CVITS; BtlltB EIUIDS I
1 1
t 1
) 0.99 ug/g dry «t I a) coctet I Caapbell, B.C.
I I. 10 ng/g drr «t 1 t) Stei I Seattle. l.D.
I IgtonsT saaples | Elliott, B.I.
1 I eoldberg, ».
I 3* yr old aetal cocacr. eipoael I Boors, B.B.
| dicing a baildiag deaolltloi 3 ao 1 Beerer*. D.5.
I earllert Killed U industrial I Tree, 1.
I accident. ( 1979
1 1 Ircbivas of
1 lMo*l»l craaps. coutlpatlon. 1 Eariraaaeatal Health
1 .eiiting, fatlqiej | 3»(6) :»39-»»3
1 1
1 mo: IEID tcisoiiiG; ISDDSTSIIL i
1 EISI1SI5; IIBOsnilI PCllonci; I
1 cioci: cist iisroiiBs; imopsirs: i
t met: iiBiiis; *nTES; BIIII; tins: i
| IIII: 11 TIP 5 90115; OIITED CTIGDOB; I
I ItOlTS; 9II11B BlItSDS |
1 1
(»1II MSB)
                                                                                                                                                                                           oo
                                                                                                                                                                                           o

-------
7«»-92-1
Fb
Itl 207.1, el 327.* C. BP  IT«0  C.  T» T.7T » B« «t 10011 C.  1 •• Eg at 970 C, It u 14 at  1160 C
                                                                                       (COIfXRTOD)
HSSfS


1116
Braia























• 117
treatk











1118
8r*atk












• 119
•air









IKS1SI BORE



























Inhalation












Inhalation
























Hitmen.
BET BOB

US
























PIXB












Mil













US










I08.EES
OF CIStS


























1












1













a) 31
b| 22









MISI


0.051-0.152 ag/g
0.012-0.050 ag/g
0.059-0.112 ag/g
< 0.010-0.018 ag/g
O.oat-0.183 ag/g
< 0.008-0.026 ag/g
•at wt


















99-0.03 ag/ca a












not giTaa













a) tot given
b) lot given








(III
Bill | SIIIS1L IlTOtSaTIOl
1
1
0.067 ag/g 1 •! City ccsltenta. ioaar floors.
0.039 «g/g I total Pb, 8 nb-]ecta
0.087 ag/g I tl City realdents, lover floors.
0.011 ag/g 1 trlsUtyl Pb, 8 ssbjecta
0.07S ag/g I e] city reaidents. apper floors.
0.011 ag/g I total Pb. * aablecta
at vt 1 <) CltT resident*, appar fleers.
Mdiaas I trialkyl Pb, a subject.
j <> Sifearbs, village residents, total
I Pa, 10 sablects
I fl SBBarbs, village residents.
I triaUyl Pb, 10 aob-lects
| Decreasing it levela vitn increasing
I age (P < 0.05)
1
1 latopsies. lesideata of Copenhagen,
( ita stbarba, aad of vlllaqsa oa
I Zealaal. lq«s 12-S» vr.
1
| finall: 1BDUS; 1DTOPSIIS; cRluni;
I EMIR; in poiLtrtioi:
| E10aCC9fl9UTlaa: 01BII UE1S; LIIB
I C1SUIC COHCOIDS
1
1
lot glvea 1 liter aatoaotlve Pb fcalide aerosol
I eipoaara. levels a finctlon of
| particle size. Zstiaated fro a graph.
I TUal valaae of about 900 ca s ant
1 riselntorT freqaeacT «f 15
1 cvcles/iin salatalnei during 10-ain
1 aaipllag tiae.
1
| IStlTH; ISORKB: CaLCIOIl; C BIO SIS!;
i mi: 17TOBOTHI: ttmspsni;
1 PIBlICOUtTS
1
1
6.6 ng 1*1 saapled at rate of 1 Vela. 2-10
1 aln after earalag 8 arc mldlag rods.
1 I«ar detect lea liait.
1
1 aai.wcsi.tT pvysics shop, Florida
1
I noBioi: moils; BBIKB: ULCIOR;
1 CStOSnP,; CIBORXDR: COIPBR; X10R;
I IlIC; 1M6IIISE; nCKII; TOT1SSIOR;
I suirira: Titinm; THioroB; me; IIB
1 ecttntOI; f«8ES; IlOfSTBIlL
1 iTHospHies: met nsntrs
i
I
a) 23 ppa 1 a) learaiag disabled
b) a ppa | b) Controls
1
1 leaniag ditableS and aoraal 3rd and
1 «tt grade atadents in Canada.
1 CltCIT*: RietSSIOR; POTASSIOR;
I SO CIOS; CltHIDR] COIUT; COPKB;
1 Itoi; !.«»; auetiESt: zxic;
1 eetCBH*: iitnoR; uncoar: RETILS;
1 HilB; CSI1DBII; CltlDl
I Past)
ttriiegct


i«lsen, T.
JeBsea, K.I.
Grandlean, p.
1978
tatare
273(5*71) :«02-C03



















D«saedel«er, E.G.
llBCkester, J.V.

EBVlroaaeatal Scleace
and Techaologj
9 (101 j 971-972







ItselssoB. K.B.
Desaedeleer, G.6.
Johansson, T.B,
VLacheBter, J. R.
1«78
IBaals of Occnpatioaal
Rygieae 19:225-238







VU1, 8.0.
p*rkee, a.
1977
Science
1«at«13) :20»-20«







-------
Pt
1W 207.2, B« 327.4 c, IP 1T»0  C,  TP  1.77 HI Bg at 1000 C.  1  •• Bg at 970 c. 10  •• (g at 11«» C
                                                                                 (canntmi
TISSUE
Bali
4121
•ait
• 122
Bate
4123
la It
iiposni ton




ItUTtlClt
ffXTBOD

1ST
US
ElaCtCOCkai
•unit
or cisss

t
aj 45
hi 70
cj *4
a) 65

mei

1.S3-7.«T BS/J
a) 15.3-19.7 «g/g
b) 19.3-59.< •«/»
c) 13.9-16.9 OJ/J
1) 4.0-13.7 afl/g
at gt»«o
Sill | SEIM1I IBTOMITIOW | BBPIBICt
1 1
1 1
1 liTl«. 24 ncnswatatln 1 CLlttlebanagh., S.
1 tt«-4uL|lla tr«atsj««t« are I 1980
1 tab*la.t*4. Ik* fvastblU.tr of a I sci«aca of the Total
1 koltstle, ao-vask palter for latr 1 CailronwM It: 53-75
1 «a»lTHs Is oatliaei aid supported. |
1 1
i iiritt; met IZMKHS; tins i
I losnuii; BasotKBiir BETHOIS; \
\ enusi pMTFiist coBptimn t
I iTiiniiois; itoBjioa: IRIKHI; i
1 iBsnic; sum: BBOSTW; cumim; i
1 C11CI9B; CnCBtlB; CBOBXOB; COBI1T; 1
I copptit siitrui: sminus: GOLD; i
| tOBUB; ItOB; IltTSITOS; Hit; |
i Rie«Bsimt Bueaitsi; SIICHBI; i
i ectiBHim; ixcKn: PHOSPEOBBS; i
I EOTissm: siBiDimfi SttMiosj i
I siiicai; SIZIBS: soong; sisciiniB: t
1 Sturm ; TIB; TltkWIOB; TVBGStBf; |
1 n»c: Tiicoiiffe i
1 1
1 1
».»0 » or - 1.33 ag/i I Jaacd kaic - 10 «k perlofl. BailT I Chtttlcboroagb. S.
I «OM« Of 100-300 K <•• 29 | Steal. B.J.
I aatoralaatteis. t 1980
t t Scioaca of the Total
I lajittalla | EaTicoaMat 15:25-35
I iDsranii; em; GOHTLMHTZ i
1 ITltaitrors; c»»n»s; coritB; itttt; I
I Bitus: tsici it tains; tuc i
i i
1 1
a) 2».S ng/g | a) Bales. las laoales I Johnson, D. B.
b) 29.0 tg/a | t) T«aalas, lo« Inqalcc | Pravast, 1.1.
e) IS. 1 cj/a | c) Bales, laacastar I Tillecj, J. B.
3) 9.8 ng/9 1 at Maalas, laacaster | caaau, D.E.
Seatetclc a«a>a i lt«as Uffcni p«.OD1. Talaes for | Bosaafaia, J.H.
1 loag katr. | 197C
1 1 EP*-600/t-7«-019, 235
1 tniLS; niimi; piuitiaB; Lsio: i pp.
I lopratTtoi Eiposmx; OCCOPITIO»IL i
1 nztsis; cturosni: IWOPSXIS; i
I ttooo; viiiETS: Sfiinr: BUS; naivi; i
I tSiCS; TCSCUS; 1MPOS! TZ5SIX; I
I IITW; CONPlUTtTt IT«ltJlTIO«S; R1 1
I JE1SET; Ckllll; SHIBS; IBTOBOTITI I
1 1
1 1
45.17 tg/t»T: si CUTS: IESTES; BULXB: mis; i
1 B»IB; llfEt; MIES; OHIID mSOOH; |
1 ItDLTS; BCU1I BUklDS |
1 1
                                                                                                                                                                                 00

-------
Had
7««-S2-1
tt
Itl 207.2,  It 327.* C.  BF  1740  C.  » 1.77  ••  B? at  1000 C.  1  •• Hg «t  »7« c,  10 •• «« at  11C4 c
1ISSIB


«««
l«ir





















«12S
Baart













MM
(IdMT













KfOSVBE BOMB























































UURICll
BRBOD
























El*ctcoch*a














US














BOBBIE
or CUB
























1














•1 »2
b| SC
C| 11












•IKS

























lot 9iT«a














«) 1S-2W p;i
b> 15-10* ppa
C] 1.«-7« ppa
Isk vt











•III | 6BBIBIL IirOIBlTIOl
1
I
| 1 ml« of trorld lltentac* OB tha
1 acc«»al«tloa ad biaoracatra^iai of
t Ml«et*t toxic tr»c« >«t«la i» Vi»«
I litt til vail* »md ottet laiullu
| l*li, fmr. ••!!•> cl«« *Dd boot*.
t l»l»l»t«4 bi 9«oqrapUc »r«t.
j ««b-}«ct3, ami, «4*. «xpo*«c«
I gc«Umt, a>U.T*M la pp«, an*
t *itkoEitr £«• OT« OO E«f«c«aora.
I
1 mictj lasiuut: ciiuta; cnrui
I itinci; tJMH: nons wst: in
| Illlin; SOUTB IBEBICI; SODtBBiST
I Jill; DIKZD HTCDOI: OflllD STITIS;
1 itii: vuis; mm; iirnoit;
1 iismc; toieis cwmii: cnmni;
1 COIllTi COHM; 1UB; (1I8COSI:
I 1ICRI; SfLJIIOB: Tlli T1HOCTS; til
I lomrtToi: iiiRiL ?ointnio«s;
I cioiccvniMioi: BIOIIBICITOBS; L«B
1 loiiotioi; ro?otiTio» tiMsnsE: urn
1 tctLtmow: TUCI nMiirs; ait its
i
3,90 09/9 dry *t I latopST •••(!•
1
1 36 ji oil Mttl tm«c, «iiK«ea
1 avclio, a b«lldlm« lawlltloi 3 «o
1 «atU«c. 1111*4 in liflvstiial
I ioeU*at.
1
1 ItJoBltal ccacps. co««tip»tioii.
1 Kiitlag. fating*
1
1 me: u» icisonie: iiDustint
i nsnsts; iitnnut *eu.0»c>;
1 HOOB; CIS? CISTOBIIS: ITCOPSIIS:
| IllBTj SIDltTS; IEBTES; BBIIB; ItlLS;
1 But: itiis; BOIES; mmiD moron;
I ItntS; BUI1B BIU1I1
a) 52 » oc - »7 ffm I a) Hack a««lt*
b) 3« » oc - »» pp« 1 t) Caneailai •Salts
e) 26 » oc - 23 FP« 1 e| Ckllitn
Mb »t |
1 latopalM fcoa hospitals It Roctfc aid
1 Seat* Cacoliaa. Blacks and
1 CnetaUM. Idalta. a«*« 1«-91 re.
1 Ctilliea, agai t day»-t it.
1 MTIT.S-. SOUS; LITEt: SToaitS:
1 ItfflTS; CBTlDBf; CIDHOR3 IMC;
1 UK; BOITB CUOlIIl; SOall CMOLII1;
1 IBTOPSISS: BIOiCCBHBLlTIOi; BlCIlt
1 S1VCTBS; IOB; SIWKIIS; TOtlCCOSi SBI:
I iconuM
i
(HIT »l«t)
BE7BBBICE


JoakiBS. B.I.
1»79
FPI-600/»-79-fl«9. ISk
PP.



















Caapbell, B.C.
(•attle, 1.0.
Elliott, B.I.
«oldbac«. 1.
Soote. S.B.
Bvwreca, D.s.
TE««V H.
nn
Ir eh lies of
EaTiraDMOttl Etoaltk
3«(S)t«»-»»3





Raaaer, D.I.
Caloccl, ».T.
BaMolblad. T.
(llllaas, I.E.
Plakecsom, c.
1«73
Joacaal of Oceopatlooal
Hadlclne 15(12) :*56-1«3








                                                                                                                                                                                           OO
                                                                                                                                                                                           U)

-------
lead
7*39-92-1
Efc
>t« 207.2. Bt 327.» C, Bf  17«0  c,  It 1.77 u Ho, at 1000 C, 1  m*  B«. at  970 C,  Iff a* H9 at WO C
tISSOl



»127
Kidner























»128
Kidney














«W9
Iver














EIPOSOBE BOOJ




























































alliniCal
BET80D


its
























Electroehen















US















•OTBSB
or USES


a) 9
») 9
e) 11






















1















> «o
) 60
ct 1»













MRGE



a) 0.10-9. £0 ag/g
b} 0.15-0. «» ag/g
c) 0.0093-6.70 ng/g
let vt





















lot given















) 15-517 ppa
) 15-785 ppa
) 0.7- 1ST IPS
sh «t












an* i SEIIBIL iiroBaaTioi
1
1
1
a) 0.23 ng/g I a) Controls
b) 0.34 ag/g I fe) Barker group I
c) a. 29 ag/g I e) Barker areap II
let vt |
Bed la us ( teceasad refinery and anelter
1 eorkers, agea 55-76 rr. exposed to
j keaTy aetals 1-3 decades. liac
I ketveen retirement and death 0-1.5 yr
I In group I aad 2-19 rr, group II.
I Controls, ag«s (3-72 rr. iho lived 50
1 ki froa the factory. S«ed«n.
t
1 SUCK; ClOaTIBS; KIDfETS; LITSB;
I tClSS; COBPIBaim ETLlBaTIOBS;
| IIDOSTIIlt 115IEII; RaSOSZIER
I tir sorts: immni: ustiic: CIDBIDB;
1 C1SIDB; CBI09IOH; COBUT; COPPEI;
1 eoie; iioi; IUTBIBUB: LE*D;
I MieiiESE; BiscvET: •oiraoEWB;
1 IEOSPBOSOS; BOB IBM »: SC1SDIHB:
1 SIlEltm; SI1TIB: TIB; TdlGSTEl;
1 ziic: BEaiTH airiBDS: iroasTEiu
1 flittS; SBIltEBS; TELIHSIOB
1
1
2. »8 ag/g dry vt | lutopsr saaple
1
1 3< yr old utal turner, exposed
( daring a building deaolltlot 3 ao
I earlier. Killed In Industrial
1 accident.
1
1 Itdoalnal ccanp*, constipation.
1 Tcilttna, fatlgaa
1
1 I tit: ma POisoiifG; iioosTEliL
t cisnsES: IIDISTBIII POU.DIICH;
I EtOOP: CISt BISTOBIIS; aOTOPSIES;
1 BEHT; KIDBirS: (EITES; BEIII: B1IIS;
1 Bait; 1ITEB; BOIES; 01IITID KIBGDOB;
1 ICOltS; BEalTH BlZltBS
a) 96 « or - 108 ppa I a] Black adilts
b) 69 * or - 11* ppa 1 b| Caucasian adalts
O «» » or - «S ppa | c) Children
sh at 1
1 latopsies froa hospitals in north and
1 «o«*k Carolina. Slacks anJ
1 Caeeaslaas. Halts, ages K-91 yr.
1 Children, aaca % da fa- 6 rr.
1
I cims; BOIES; LITER: nniETS:
1 HDITS; CBUCBEIi C»D«n3; ZIBC:
1 U»D: mm CUOLIH: SOOTB cieotiri:
1 aVTOPSRS; PIOICCTB011TIOS; IKIaL
1 JTOCIfS; a«Zj SBoniG; TOBICCOS; SEIj
i itonisBS
i
lEniERCE



Brane. D.
Bordberg, G.
•ester, P.O.
19BO
Science of the Total
Environment 1C: 13-35



















Canpbell, S.C.
Seattle, I.D.
Elliott, B.I.
Goldberg, a.
Boore, «.B.
Beevers, D.S.
Tree, R.
U79
lEchires of
Eariroaaental Health
3«(«):«39-»W





Banner, D.I.
Caloeci. 1.1.
BasselBlad, T.
Billiaas. B.C.
Plakeraoe, C.
973
Jonraal of Occepatlonal
eliciae 15(12) : 9W-963








(MIT P1S1)
                                                                                                                                                                                            03

-------
lead
7*59-92-1
n
It* 207.2, n 327.* C,  BP 17*0 C.  TP 1.TT M Sg at 10OO C.  1 u Hg at 470 C.  10 » tg at 1160 C
                                                                                     tconn HID)
tissm

«3«
Itnr




















• 131
Livec














•132
lomg





















iirosnx IOOIB



























































IBlLtnCll
mffoo
us




















Electrockei














IIS





















•OBBE1
or CISBS
) B
1 9
e) 10




















1














a| B
b| 9
d 10





















B1IGI

) 0.21-0. 55 89/4
) 0.39-1.0 ag/g
1 0.28-0. «« *g/?
Set It



















lot given














a) 0.00*4-0.17 nj/g
b) 0.13-0. CC ng/g
C) 0.07S-0.32 19/9
let lit




















•til | 6IHML HTOSBinOI
1
1
) 0.211 ig/9 | a) Coitcols
) 0.63 ag/g | t) Worker group I
c) 0.36 «g/g | e) torter grotp II
let wt |
Bedlams I teceu*} nflnerf a>4 saeltet
1 »cfltet«, a«e« 55-76 jr. erpo«el to
1 >ta*T Mtali 1-3 t |
Xediams | teeeased refimeCT amd melter
1 motkecs. aq«« 55-76 yr, vxpoaed to
1 kta*T metals 1-3 decades, time
1 h«tmm Mtlcememt ami deatk 0-1.5 TX
1 1m gromv I amd 2-19 yr. group n.
1 Ccmtrols. aqem 13-72 rr, >he lived 50
1 ki from the factaxr. Svedem.
1
1 sttiti: cuivns: RIHBTS: HTSR;
1 IDIGS; COBPIBITIW miniTIOBS;
I IIDDSTRIH 1I«Itn; HSISOBEBEUT
1 Bmoss; iBTMoit: msraic: cuaios;
1 cism; cuBOBioB; COBUT; coppst;
1 ooto; »oi; iMtuiOH: HID:
I fiieiiisi; aiBOJBT: MiTSDium;
I fBCSPBO«!lS; BSBIDIO": SClIDlni;
| Sflt«I
-------
l«ad
1*39-92-1
fb
atl 107.2, II 321.» C, BP 17*0 C, T* 1.71 u lg at  1000  C.  1  aa Sg at 970 C, 10 ae Eg at t1«0 C
nssm
•133
1.1*4
«13«
(all
«13S
i«ii
«IM
••m
IXMSIIB tan
labalatiaa


1
uitmcu.
BBTBOD
ladloMtri
Ilectrockea

nectroclea
» «-7I pg
b) »-S a«
lot glTea

t given
mi i 62 HIM ZEroiimoc i HFEIEICZ
i i
i i
»1 30 pg | •) Ifter 23* Mcacol lepositloB of | larro*. P.E.
b) 3 «g I carrier-free PbCW labelled «ltb I Belter, B.
1 »*203 | tuto, F.
| t) Ifter 26* aerosol deposition of | «ibb, r,B.
1 f 1203- labelled ?b(OI)2 | 1910
1 Fictlcl* «iw. SS4B 0.2? » | CericaiMBtal Sewarck
t >««• r»«plr«torr b«m« of tt>2O3, 1.1 | 21:313-38*
1 iCi U a) and t.« tCi i»'b|. |
I I
1 20-5* it ol4«, S5.0-9S.4 k«. no I
1 biatocr of palMncr aiMin. |
1 1
_ i mat wiss: comtinn ITIIO»TIO»S; i
• t IIOOBJ tniiinoi; in toumoi; t
1 (lASOTtHEK IRBODS; « OBITS; IEI TOSS |
59, 5» o»/j Ory >t I litep«T 1 Cupbvll. B.C.
1 1 Mattl*. l.D.
1 I« TT Oil Mtll feWBCC, •XPOMI | Elliott, E.I.
1 tltUt a bvlUi«« a«*olttloi 3 M I 6ollb«rg. 1.
1 «acli«r. Kilted tm iiJutciil I loon, I.I.
1 icclteit. | BMT«». 0.5.
t 1 Tree. B.
1 Ibtoeiul ecups. coutipatlo*. I 19T9
1 loaltlia. fatiam | irchl*«8 of
1 1 tB»iroB»e«t«l Health
1 met mo rcisoins: mosniu i 3a|6u»39-««3
1 cxsMSES: iierartiii POILOTIC»: i
t HooBi cisi nsTonis; »oroest«j; i
1 HUT: (loins; nuns; aim: nits: i
1 IHI; UTEl: BOIES; VIITIB MISDOI; I
1 ItVlTS; BE1III BlZlIVS 1
1 |
I |
t 1 r«ri«* af rorld llt«r«tor« o* ttt I Jttkltt, I.».
I aecualatioa a«d bloeaioeBtratioB of I 1*19
1 s«l«et«i toxic trace i«tal« la KUB I Eri-COO/«-79-0*». 18*
I kiic a>4 Milt t>4 otker MmBaliaB t PP.
I hale, far, mil*, cUva tad boots. I
1 Tit»l«t«« br vcoorapble area, 1
1 aablects. *ei. a«*, expomra I
1 ara41*at, aailravs la pp», aid I
1 tatboritT ftci over MO refermca*. I
1 I
I «mc»: ivsTiu.ii; CUIDI; cmiu i
I iiiiicij CT»CTt; irtim.i cast; m i
I tium; SOBTB usiict: sonnasT i
I ISIl; »n*D IIISDOI; OKTlt ST1TIS; 1
I tut; tans; BtriCT: atriBon; t
i iisEsic; soicij cunn9i cncnim; 1
1 ccsiti: ccprii: LHO; Biscni; (
i iicm: sntinR: HI; THIOHHJ ui i
i icttotioi; imu MraLiTiais: i
| BieiCCimtlTIOfl STOTICTCltOK; till I
1 tcumai; porounci BIPOSHII; IITR I
| fCltintOI; TUCE ItMIITS; BET1IS I
1 1
.*« ag/} drr it 1 l«tcp«T *aipl«. pettpkeral »«r»e | Caapball. B.C.
1 | I«»tti«, 1.0.
I 3C TC oil Bttal tittaec, expoMl I ClUott, I.I.
I 4»U« a bnlUlaq AMolltloi 3 mo | Goldberg. 1.
I earlier. Killed IB ladwtrlal I Hoore, B.t.
1 aceldmt. I Beever*, O.G.
i 1 Tree, 8.
1 Itdevlul ctaipa. eoaatipatioa, 1 1979
1 tcaitiaq, fatiiM I Ircklvu of
1 1 EBTlronM*tal Healta
I HID; mo MISOIITC: iionsniiL i 3«(«):«9-«»3
t cisMsts; mgstitii pounioi: i
| IIOOI: CISC HSTOtlEJ; IOTOPSISS: I
1 inn: Ktvins: IHTM: etui: »iis; t
| lilt: UTtB; BOIES; H1ITID ttlGBOS; I
| I1I11S; K1H( UUCDS |
I 1
(•in t*s«t
                                                                                                                                                                                         oo

-------
I«a4
ft
Itf 207. 2, «P 327.* C. It 17*9 C, ?P 1.T7 •• •« at  100» C,  t  •• lg «t  97« C. 10 n If at tlSO C
«««•»



• 137
Sall»a









,„,
Srlaal
eoct











1139
TMtb
















««0
Math
























irosvti toata



























_
lakalatlo*

















I*g*«tio»
lakalatloa
























klltmCaL
BCTHI


US










J-ral spectra*













US

















us
























nnn
OF CaSBS


at
11*
31
33







) 7
b» 12











.
al 3*7
b) 323
cl 690
11 597
•t M













371
























•net



lot glv«n
lot gl»«a
lot gliea
lot gi»ea







1 11.2-113.0 ag/g
1 C.1-3I.C ag/g
Brj «t











a) lot giro
bl lot given
c) lot given
a) lot given
•1 lot given













a) lot glraa
b) lot given
c) lot give*,
d) lot given
•I lot gt*«a





















U*f 1 Canm irVOtltnOW
1
1
1

1 «J.2 «g/l | b) totter*, *teel ladaxtry
I 94C.3 »g/l I el aorken, battery factory
I 2220. S ag/1 I d) corker* . ncortary Pb aaelter
^
i 17-C3 yr oia caacaalua
1
| ClllBk; a WITS: BLOCB; SUIVl; n
I TITO imisiS! KID: HTHS;
| CCCOPKlOIll Bit UBS; g«LTC>S
t
a] *J0.7 « or - 36.7 I at lotoc aaacoa OlMaat* patlaat*
•g/g | bl Coattoli
b) 1». S * or - a.7 | Imtral kotn tlainc, aatopa)
ag/g I
Dry at I f atUata aial of ayotropkic lateral
I *claro*l* aa< progr«aalT« aucmlar
I attopby, a«a* aq«. 58. « » or - 13. 1
I ft- Cottnli 4i«l of yaclona
1 aiaaaM* at C0.9 « or - 11.1 yr.
1 mis: isoiTS; konmisi
| ItUtOSTSCOUS DXSIaSIS; Smal OOBV;
1 iiokccnmitioi: cticias: coppst:
| HOli HID; IU6UESI] SITU.S-.
| SttBVlQBs X1IC
1
a| t.77 ag/g dry « | 1} Boyi. lr«l 1
b| 4.9* «g/g 4ty «t I t| 61rl«, Itaa k
c| «.»7 09/9 dry wt 1 e| Ban aad girl*. Ina 1
41 *.92 ag/g dry «t 1 t\ ChlUcea Uvlag 1m kcea I slaeaj
«) 3.0* ag/g dry «t 1 ilrth
1 c) chlldrca. ar«a a
t Ina 1. kcavilT Udntr'lallnd city.
I IMB S. aabacban/raral area
1 Coacmtr at to* lacraamd vltfc ag«.
1 ».6VTt.
1
1 Qaraas ?-T2 yr olii. llvlag la
1 BalBbarg, lakrdlatrlct ail
1 Cuaavrsback, B*xgl*eha> laad.
1
1 tnnnt oiium: TBSTB:
i iioiccvmiTioi: mosmat
i i«issto»; neu laiis-, IHB
a) 32 ag/g 1 it Tr«at«d •acapbalopatkr patleiti
bl 29 ag/g I It Traitad Pt-polsoalig patient*
et 33 «g/g I c) Vntnataa aablactB with klgk
d) 58 ag/g 1 blood, kigk or leu tootk Pb l«T«la
a| t2 ag/g | at Qatcoata4 aab^acta vitb low blooa«
Mk «t I klgk tooth PI 1«T«1*
1 «) VBtraated ambloctai ulth la* blood.
I lo« tootk Pb l«T«li
I
1 Chlldraa la Pb raglctrr of iy city.
1 ilUlag* o( toqictry cas*a aad daatal
1 clinic satlaats. Host trace black.
1 yc. a«m 2.3 yr.
1 Rigfc laeld««c* of p*yekologlcal
1 nfarrala ail behavior problnc la
1 a), b|. e|. CoBTBlcioas la •
I tatlaats. » «f * •keaphalopathy
1 patleat* MBtally retarded, BOB*
1 atagaomd orqaalc brain ayadroae or
1 Mine* llsoiiler*.
1
I itit: inns: cuiisM; nt
1 PoitTtio»: inr ton: ami rcisonte
l tiBMios nsdoiis; imi9>iio«:
I EiooB: fiRit tuns
i
nrainci ' '



*•». l.I.S.
981
Jovraa.1 of toxieolog}
aad VeTlrobBeBtal
Health 1: 273-2*0






Karlavder. H.B.
fattea, l.a.
1979
lanal* of 1C* urology
M^l >21~2k









Smta. B.
Brockkaos, l.
Sentec. S.
Schvraau, I.I.
1979
Intenatlonal archive*
of Occupational and
Enrlroowntal Bealtk
«*t«5-80









klbert. I.e.
Shore. I.E.

strehlo*. *cl
SBelp, T.J.
Pa»t*rnack, 3.S.
Trledkoff. l.J.
COI1B, T.
Cialao, J.I.
197*
laTlronHBtal Health
r*npeetl*es 7:33-39














HUT ««)
                                                                                                                                                                                              00

-------
7439-92-1
Ft
It! 207.1. IP 327.* C. B* 17*0 C, TP  1.77  a*  8?  at 1000 C, 1 •• Bg at 970 C. 10 •• Bg at 11«0 c
                                                                                      (comma)
1XSS01
4141
Urine
4U2
BClM
*1«1
mine
41*4
Urine
•14S
Hri*e
Birosun BOOT
Ink*, lit! OB

(Oestion


IBalTCICM.
BRBOB
IIS
us
BS
US
T
•nails
OP C1SB

«| S9
b) 77
C| 51
d| 70
*
32
7
22
2?
10
II MI
8-40 «g/l
•) 11.6-15.4 «g/I
b) 4.1-12.6 mg/1
e| 8.0-9.6 ««/l
d) 6.C-9.7 «g/a
-
27-38 s«/d*r
1.3- 16 uol/2« ir
0.»-1.5 iBol/24 kr
lot 9iT«n
lot girt*
lot given
Sit I | Gtllttl XIPOBB1TIOI I BmgEBCE
• 1
16 «g/l | 20 aaaples i I*g«*son. T.
1 Direct deteraination and attraction 1 Indrasko, I.
j troc«d*r*s agree, j 1971
1 1 ClUical Ckviistcr
1 »«ld«r«, quiq* p«c«o*D«l aad putty 1 25(11) :19»8-195J
I *crk«c» In s»«dt»k airpl«>« factory. I
I 1
| IICOSTBIlt fdlVTtai; COBMB1TITE I
| (TllgiTIOIS; ClBBinU; SVIDEI; IDULTS; |
i BIOOD: nnt; BIOICCOIOIITIOI i
t i
*t 13. 2 a«/l | •> t«l««. 10* l»aele> 1 jotason, B.B.
b| 10.3 ag/1 | 11 ?«•«!•«. toa lo««l«« | Fravost, H.J.
c) 9.0 mg/l I e] B«l««, Koetatcr I Tillarf. J.B.
4) 7.8 na/1 | i) P««»l««, U«c««t«r | Ca««nn. D.I.
SoOMtCiC •MB» | 1 ROMBfeld. J.B.
1 Californium ll*li« 4an«in< fro* • 1 1976
I fr««*T In 10* i*4*le* or 1* th« high I eEl-«00/1-7C-019. 235
1 d«««rt rcqlo* of l**c**tcr. »j« 1 pp.
1 groapa: 1-16, 17-3*, 35 or »or« yr. (
1 «fl» *Ut«. «M ioi-«ttte i* lo« {
I l«g*le*. 90t *Uta, JW oon-whito 1* 1
j t«*c**t*r. i
1 1
I KlllS; niTXIBB; PUUDIOfl: LB1B; 1
| EOPOUTIOI ZIPOSHZ: OCCDP1TIOM1 I
1 Bitiits; ctiiroini: toropsnsi i
I HOOD: KiDirrs: spiiiu am: mat; i
1 miss: inscizs: ADIPOSE Tissue; i
| IITH: COBPIHTin millTIOfS; •!« 1
1 JMSIT: cmti: sums: imOHOtivs i
i i
I i
32.75 ag/4*y I Iicntio* «od«r **liia>t conditions I B*al*o«lti, B.
( <«nfilt«red alrl doriacj 41-124 a*r* I *eth*rill. l/2« he | r| Controls | Doss In  goat, 1 landy, :.
I tc prior Pb «rpo*ore. I fedeen, E. p.
1 1 1991
1 32-78 yr old qont patient* | «e< England Jowwl of
1 1 Bedicine 30»(9V :520-523
| •« Jt^5IT; IOH1TS: KID1XT DISEaSSS; 1
| licet; 1IT11; if» |
I 1
                                                                                                                                                                                          oo
                                                                                                                                                                                          oo
                                                                                    (BUT IkBI)

-------
lead
7I3M2-1
ft
Itl 207.2, If 327.* C.  tt 17*0 C. TV 1.77 mm B« at 1000 C, 1 as Ho *t 970 C,  10 ••  B?  it  11S» C
                                                                                      (COITXItrZDI
xisss]
414*
«Cl«e









BUOSVIB IORZ











nimiciL
BBTBOD











• OBEBI
OF C1SK
93










tllGI
a) 2-230 «g/l
b) 200-4500 »9/2» br
c) 10-170 og/1
4) 200-4300 ng/24 hr







IE* I
•) lot giiaa
M lot givaa
e) let glvaa
d) lot gi»en







GEIZlal IirOKBkTIOI
•1 loachelated Pb, la 48 vorlwc*
•ipoaed at least 1 TT
t| MM-bouad Pb. la ijroop (a)
c) ioneti 31
b] 22








SalCl

0.20-0.61 eecj/1







a) lot gl**a
b) lot gltea


















a) lot givea
b) lot «!*••








Bill

lot applicable







a) 0.78 « or - 0.01
aeq/1
b) 0.48 * or - 0.01
aeg/1
















a| 0.22 ft*
b) 0.40 ppa








S11ZUL T1TOBMTIO1 |
1
faage of Maas
Dose, SO 0-500 ag/dar as carbonate.

Depressed patients

iniTDa: BLOOD f 11311; BZTU5:
CBimmitpT; IEIVOVS SISTIS DISUSES

a) laasas City, IS, bard-«ater area
b} Kaasas City, BO. soft-sat«r ana
SigalflcaBtlj higher lerel (f<0.01|
!• bard-cater area.

IS aad BO r«si.d«ts satcbed for age
(Mat aoaa 37 and 37.7 yr> . m.
leaotb of rasldeaoe. aarltal aad
eeoaoaie atatas, oecvpatioa, Basber
c( chlldt**. uoUaq habit i. hi, *t.
la bard-«at«r area, significant
itexaaa* 1* hivertemslen, VX
ataoraalillts, aid bTpomiccsla.
ciHU: iissotnii; .DHT.TS:
ClltlCTUCniK DISHSSS:
BIPTITI13I01; BLOOD SI BOH;
ciicna; ciicBTDB; LITBUJB:
BismiiB; pHosraoBOns; rotassioi;
SCDim; me; BIO1CCTF5U11IIO*;
ISIKHS vitn
a) learalag disabled
t) coatrela

learalag diaabled aad aoraal 3rd aad
4th grade stadeats la Caaada.
cmciuB; BiGitsun; potissms:
sconi: ciDaiDS; COBH.T: conn;
:«3i: L«III; uiGinsE; tuc;
c»onn; mnoB; azsonti; BRU.S;
itTi: cniufii; CMIDI
BZTEBEICE

Balliager, 1.6.
Balllager, J.
Rlaialhocb. J.9.
(ell. J.P.
Baain, I.
1990
PBrchopbaraacologr
68: 249-255
Blecaaba«a, B.L.
TlelacliBaa, I.I
Doan, J.
Irhald, J.
1975
laacet
1 (191*1 -.1008-1016













Pitil. 1.0.
?»k*e, 1.
1977
Scljeace
199 (4313|.:204-206





                                                                                                                                                                                             oo

-------
 n-Pkenrlenediuine,  (-Mtkoir-  (8 CI)
 1,3-EeaZelM«iaalne.  *-netkOII-  (9 CI)
 C 15-05-a
 C7-110-I2-0
 II  138.1
HSSBS
• 150
Orine







I
I
Hfosm ions











iiiiTticu
IRBOD











•ram
OP C1SSS











SUSS










1
on









1
1
sunn moBimo*
SeTle*. local aaa STatenic effects
relating to kale 4ye fornulation.
iigccdint t««ts. aad «rp«ri«nc«« in
MI »nl iiliali.

KBITS: niBiWius: Ropiisgs; asm:
I* T2TIO IIHTSISi II TITO 1I11TSIS;
t'TIIt; OTIS; CUdlOGZI; COSHBTICS;
siimc inters; BIHTH gizmos;
•RlBOtlSI; 8R1B01ITBS

U7IREICE
Banolli. r.I.
erces. s.
Mibach. H.I.
1«7«
Journal of
ZBTiraaiental Pathology
and Toxicology
1:589-530



l-lolgaiid*. I,f-di«tkrl-  (I CI)
(•nuiid*. l.f-U«t1iTl-3-utkrl-  («  CI)
13»-62-3
C12-B1T-I-O
II 191.2C. Bf <2S C, BP 160 C at  19  u I«.  Ill  C at  1.0 mm aq
1ISSOI
• 151
Blood










znosots BOUTS
DKWl










nil men
HBTBOD
8C/HS










BOBBIE
or cists
i










«»»«s
lot giT«n










111 I
0.3 ag/100 •!










CBBIML IIFOBBITIOI
8 kr after application of 10.* 9 of
DIR (133 KJ/tl) in a coiMCcial
i>a«ct repellent to about 75* of skin
aicfaee.

30 IT oil, lit 78 kcj

OltTBD ST1TM: 100ITS; B1OOO; BUWK;
nsnciais; n TITSO IULTSIS



nrzKwct
la. 1.
Pearaom, B.l.
Skekoski. 0.1.
Soto, B.J.
Stevart* B.l>.
1979
Joenul of High
Sesolation
CkTOMtoacapky and
Ckronatograpay
Coennn icatioos
2:«8-5«2
                                                                                                                                                                                             VO
                                                                                                                                                                                             O

-------
a-iTi*» ca en
!*>«••. 1,3-4i»«tafl- (9 CI)
HI-38-3
Ct-110
ii we.it,  n -47.4 c,  TP n •• Bg »t 21.3 c
tissn
4152
Blood
4153
Blood
IIS4
Hoot
MSIM BOOH
akalitloa

lualatin
iHimcii
BIT BOB
OC
ec
ec
io»n' i UKI i Btii i eiiEBit IITOBRUIO* i umncz
or cisis ill I
iii i
III I
I a) lot gin* 1 a) 8.2 » or - 0.8 1 a) Boiaay «-•-. «o*k 1. air 1*T*1 4.1 I SarolalM*. E.
I b) Bet giwi 1 uol/1 1 »oVl 1 BtlkUaU., T.
I c) Bat gim 1 b) 9.9 » or - 1.6 1 t) Roiday p.*., Mok 1, air !•»«! 4.1 I linaoila, R.
1 d) lot gira 1 aaol/1 I uoVl I 1*7*
) o) lot Jim I et 1D.6 * or - 1.5 1 c| Friday a. a., iwfc 1. alx !*»! *,2 I Xatcraatlonal lr£kir*»
I f) Bat gimi 1 aaol/1 1 •»1/1 | of Occip»tioul ud
I g) tot gira 1 d) 19.9 * or - 1.C 1 d) Friday p.*., ***k 1. coaontratioa | nvtroiMital Beam
| I a oo VI 1 ii ait Ural 8.2 uol/1 1 44:201-211
1 1 •) 8.7 » or - 2.1 1 «) Boaday a. a., cook 2, air lOTtla 1
| I »ol/l 1 llietiatlia. it 4i 1 «nl/l 1
| t tt ».4 * or - 3.* 1 f) aoiday p. a., wot 1, ale !•»«!» |
| 1 uol/1 I (lactutlig at 4.1 uol/1 |
| 1 A M.I * or - 3.2 14) loawiaai p. a., «o«k 2, air lerol I
t 1 1 I
I | 1 at 1811 ca, MI rt 70 k. | BaTiroiMStal E«altt
111 1 43:154-150
1 i i cccoriTiOMt iMitis; «EBBIIT; i
1 1 1 ItUlTS; HOOD; CatCIlOCI* 1
1 1 1 1
III 1
» 1 a) Bot gl»«i 1 a) 21. « * « - C.3 1 a) Trutmt Say t, ooastaat orponn 1 aanlalna, C.
1 b) Bot »1»« 1 «aol/l I lti«l (3.1 niol/U ( tllliUaU. T.
1 c| Bot gifn I b) M.7 * or - 27.S 1 t) 1roatn*t day f. ooastaat exponro j Soppalaiooo, t.B.
1 at lot gim 1 aaol/1 I !«*•! (B.2 «al/lt 1 liuolla. R.
1 •) lot gim 1 e) 29.5 * or - 4.2 1 c) Tnatcat day 6, following 2 1 HBO
1 f) lot gim 1 nol/1 | mitmtmt day*, coistaat »ranr« 1 Xitanttloul ltcU»«i
1 1 dl S1.0 * OP - 2.4 llml (3.7 uol/U | of Oceapatloul ud
I 1 «oVl 1 d> IroatMit day 1, fariabl* oxpomn 1 iBTironaamtal g«altk
• | 1 •} 117.3 * or - 23.8 | 1««1 (tiic-Mlgkcod avorag*, 3.8 1 49:105-121
I 1 uol/1 1 aiil/ll |
I 1 t) 48.1 » or - 18.2 t«) Troatnat day 5, variable oxconro I
I 1 uol/1 1 !•»! (tloo-Migktod avoraq*, 7.7 I
t 1 laiol/1) |
I 1 If) IcoatMBt day 6. follmiig 2 1
) t 1 ic«tx«atM«t days, variant* oxponcc 1
1 1 I ICTOI ItiM-Migktod anragt. 3.8 I
1 1 laaoVl) t
1*1 1
1 1 1 (.tilth? wlntMis. MU ao*« 23.* * 1
1 1 let - 1.4 aid 24.T * or - S.I Tr 1
1 1 * 1
1 1 1 Iipairoaat of body baluc*, raactioa |
1 1 1 tlati, aamal coocdtMtioi, and 1
I 1 Ickaogos ID EM. I
III 1
1 I irnuit; nous; noon; CO»UHITI i
1 1 1 ItlLUKIOlSj BBnniS; IBBUtTIOir 1
1 1 1 1

-------
 a-lTleae «8 CIt
 tBBSeae. 1,3-dinethyl- (9 CI)
 108-38-3
 CI-110
 B«  108.16.  RF -»7.» C. TP 10 » Kg at 28.3  C
                                                                                        (COIfllOBD)
1ISSOE
«15S
Breath













ZXPOSmS BODTE















1BUTTICU.
BSTBOD
6C-BS














mates
or CISES
54 (387
sanples)













B»«I
•Ot given













1
Bill
0. 32* ng/1
Se one trie













GEBZBal IBFOBRaTIOB
leasarcd at 25 C aid 760 as Bg
15.81 occurrence
lower and vppar one-sieBa liaits
0.0*5 a«l 2.32 agyl

Htalthy, 18*95 yr old, nonsaoklag.
at tan blacks ud caacasiana.
Chicago, n. Bigidly controlled
•ipcrlMital canditiona.
IIHTH; IICOBOLS; I III 101 S; 1DOLTS;
CKCBIMTrD BIDKOCtlBOIS; TOlltni
C1GIIIC COIPCVIDS: BZUTB HlIl'BS:
iiBit»iof; mrr»Bonss: HJTIEOLITBSJ
fCPOUTIOI (IKS01T; OSB»I JB11S

IBFKSKBCB
KrotoszTBski, B.K.
Brnneso, e. R.
C'leill, B.J.
W79
Journal of Inalytical
Toiicology 3:225-23*









lagnasioi
1»39-»5-«
B«
l«l 2*.305, BP 651 C. B? 1100 C, TP  1 ••  Hg  at  621 C.  10 u Hg at 7*0
tissnx

*1S6
lorts

















*1S7
Elool


















EXPOSOBS BOm








































tliLTTIOl
BETHOD
U






































HOBBIS
OF C1SES
2






































BIISI

110-860 ug/g (vet it)


















a) lot 9iT«n
b) Rot git ft
c) lot giT«n
d) lot giTeo
ej lot gi*CB
f) lot given














BEaB | S1IIBIL IBTOSUTIOB
|
1
•90 » or - 530 og/g I tales
(»r chives of
Invironaental Health
3S(1):3«-«*











CockbnrB, F.
Bel ton, U.S.
P«rris, B.J.
eiles, R.B.
Erovn, J.I.
Tamer, T.I.
MlkiBson. E.B.
Forfar, J.O.
Barrie, W.J.B.
BcKay, e.s.
Pocock, S.J.
1980
British Radical Journal
281 (62 32): 11-1*






                                                                                                                                                                                            VO
                                                                                                                                                                                            NJ
                                                                                     (BEIT VISE)

-------
7«3*-SS-«
             '  e;i  c.  » 1100 c, TT t •• B» at «2i c, 10 » t« «t T«O
HSSB1

aiSi
Blood,
sena






















Bra Is



















• ISO
Bail











xrosniB soon
























































1UIYTICU
HCTSOO
US





















u




















IIS











•mm
or Casts
2«0
2*0










































a) 31
b) 22










llKI

lot gi»e«
lot «lrei





















a) 79-»OC aq/g (eet «tj
b) 100- »«0 »g/g (wet it)
c) W-329 wj/g (wt *t>
d) 57-2(0 ag/J (vet >t)



















a) lot give!
b) lot glrea










mi i stum IBKHBIIIOM
I
2.01 » or - 0.01 I a) (ansaa City. IS. hard-vater area
eoyi j ») Kansas city. BO. aoft-»at«r area
1.41 » or - 0.01 I Slqalfleastli Ufaec leral |«<0.01)
net/l | i« aard-vatei area.
t
j 13 an* «0 rttfdeats aa toted {or age
| flea*. a«e* 31 and 37.7 ?rl , *ex.
I lasotk »f resideaoe. aarital aid
j eeononle itatu, oceopatioe, naaber
I cf children, saoUoq iabltm, it. *t.
1
1 la haro-mter area, Blanificaat
I liereaae i> hfperteBSlon. ICC
I ataorealltles, a ad hrperacicasia.
1
1 inns: itssOTBi: »ntsi
| CISIIOTIScatUt OISK1SSS-.
1 E1PMTH3IOI: BIOOD SJBOB;
1 CCRPIHTI^I nuonms: CIDBIHB;
1 CIICIHR; cRtcRioi: iirRim;
I BiGixsiBS; tftosrcosoos: pOTissira;
1 sctmni; n«C; BioiccoiiouTiai;
1 HIIKIIS urn
i
a| 210 • or - 100 t a) Bales, ceiebraa, t svbleets
99/9 (••* «*) 1 " T«aa«s, oerebru. 2 rabjecta
b) 270 » or - 2*0 | O Bales, cerebellea. & BBtjects
ng/a (>et »t) I o) Feiales, eerebellu, a aabjacts
ct 170 » or - 8S «g/q 1
(vat *t) | tioa a <|roap of Cl antopciei.
d) 170 * or - 90 H9/9 | forensic eedlcal aiaalaatloaa, Japan.
(•et «t| 1 (ales, aaan aq« ao.« jr. feaales.
j aean a<]« 37. * jr.
1
I TI1CZ nZHniS; IBTOPSIES: JIP1I;
1 HHRIIOB; iBsraic: CIBBUJB: COBU.T:
I cticmii; cop»!B: ZBOI: BCBCOBI;
| 1I9IUR; RIOBISIDB; RIIB1BZSI;
1 lOCIDIOB: HBTI10IT; SCITOIOH;
1 ittzilll; TI1III01; TIUBIOH; {IK:
I ectt: asonzBt: IIT^B; KIDBI^S;
t CIJIBS05; CIBEBZUOR; HIIBT; ROSCIES:
1 iHcnu: stii»i miss; xcsii;
I iniis; coKiiBinrB STILOITIORS: sn;
| IOBIBSIC HniCIRE
i
1
a) 35 ppa | a) I«anla9 disabled
b) 37 ppa 1 I) Controls
1
1 I«ar«l»BBB. J.
rnold, J.
97S
aacet
(HU(l100«-10U

















Taka«a, B.
Seiaki-TasuBOto, a.
laaBo, E.
Tarai. R.
1980
IrehlTes of
Eailronacatal Health
35(1);3*-aa















Ilbl, B.C.
Parkes, B.
1977
Scieace
198[»313) :20»-206







(HIT FUSE)

-------
1439-9S-4
»9
Itl 24.30S, ft 6S1 C, 1? 1100 C. Tf 1 M. Iq at 621 C.  10  •• tg at 740
IXSSBt



4161
Batr



















1162
(•art
















416)
Bairt









4164
IUMT



















EMOSBBC ion









































































_«__________
111LITICU.
BXTBOP























U

















US










a




















BOB an
or CISBS























at 4
W 2
















) 14
I 7









£
2

















1

MBS*
























a) 87-420 (9/9 (*»t »t)
b) 110-320 «9/9 (a«t at)
















) 94-246 09/9
| 197-251 S9/9
at »t








53-250 «9/9 (Mt vt)
57-130 49/9 (aet at)


















(am
1MB | CIBIU1 IBFOBB1TIOB
1
1
1

I prs-aaalysis treatsests ara
I tabulated, tha faasibilitr of a
| holistic. BO-vash policy for hair
( (Hirsts Is oatliMd «aJ sspported.
i ftvisB; TBtci Ennui; am:
I 18S1BUI1; BZISBBIBSBT BITBODS:
1 itTalSt PtoiHIS; COWIBITTO
1 tmoiTiois; aLBRiBim: iBrnowr;
1 nsmc: BMIBB; BBOBIBE; owios;
| C11CIIB: CB1CSIBS: CBKOBIOB; COBALT;
1 ccrtn: siiitvit; ennuitia: «jio,-
1 lOBMI; MOI; Ll«n»IOSj iBIt;
| BaSBISIOB; B1BSEBBSI; BBICOBT;
1 tcimravi: HOCK: ttosttovas;
| IOIMSTtl
-------
MgM*ill
7«3f-*S-«
«9
Itl 24.305. a* 651 C, IP  1100 C, n  1  u  14  It 62t C,  10 u BiJ at 740
1IS3H
»1«5
lllOX
• U«
l«»9
»1«7
luclo
nosnc «cim



tlURXCU.
BTTIOO
U
U
11
nnsi
or cisis
10
3
a) 2
t) 2
a) *
b) »
tllGX
1 37-750 ag/j |«*t «t|
1 M-200 »g/« (««t vt|
•) 79-150 «g/g (»ot »t>
I) 86-110 ag/g (««t >t)
*| 130-180 «g/g <»t «t|
b) 82-500 o-)/g |Mt »t|
1111
) 2*0 * or - 210
g/g (net «tl
) UO » or - 83 «g/g
•«t »t)
-
a) 110 * or - SO oq/9
(wt «t)
b) 98 * or - 17 ag/g
(»ot «)
a) WO * 9t - 11 n«/i
(«»t lit)
b) 230 « or - 1(0
ng/g (»«t »t)
cciistL MToismoi i nnmci
i
i
i
a) lain I Tokaw. 1.
t) T«m«l«B | sazakl-lanuto. g.
1 lino, I.
Jtoa » qro*p of 61 aatopii**, I Tcrai, 1.
female itdlcal •xailoatioM, Japan. I 1980
Balw, Htt aq« *0.« it. T«ul«s, I lieaif«a of
a«a» aq« 37. « rt. I miconnatal B«alth
1 35(1lt3«-M
t*»cf mints: inoMiis: j»i«; i
lUBim: ttsmc; cuuoi; COBUT: i
cnonai: ccmt; noi: incint; i
iiexiiii iisiisioH; UIG»I$E: i
HIIOIH; IHIBOJl; SCIIBIDSJ )
si»ms; Tiunoa: mioin; znc: i
6C1B; noun; inn; noiirs; i
citintn; ctitBium; m»: anscus; i
(IKItlS; Stini; 1D1SS; Mm; |
erru.it coiFit»in CTIIDITIOKS: sii; I
fCSIISIC »tICI» I
1
1
•) nalas ( Taka«t, R.
t) »«aal«« | SainU-UMKrto. a.
1 l*aao> I.
froi a IIOIF of (1 »topil«i. | T*r«l, I.
loc«asic Hdlcal uaalutioit, Japan. I 1980
•aim, aora ago »0.6 rr. Tonlos, I &cchl*«> of
!«»• ago 37. < TT. 1 Ea*lroMoatal Baaltk
1 3i(1)-.3*-»»
11 1C! ILlBtllS: lOTOKItS: IU»; |
iiomii: itsmc: CIDBIDB: COBU.T-, i
cBioaii": ccmi; itoi: incnti: i
iicuja: neiism: UKIIISI; i
mtiBitis: innon; SCIIBIBB; i
sntnvi; miiioi: wnoiti: zi«c; i
son-, Btogiit: Lint; ng*ns: i
CIBI3IH1: cnsBxiiOB; nan; aosciis; i
iiiciEis: siim: inesi aoiri: i
RtTUS; COHTIUTin MliO»IIO»S; S!X; 1
retnsic itBicin i
a) lal«s | Tnka«a, 1.
t) Toialoc | sanki-Tancoto, S.
1 aaaao. (.
ftop a gronp of £1 aatopaios, I Torai, I.
forma le Milea! oxaaliatiou, Japan. I 1*80
Stiff, fffa ago »0.6 rr. loialos. I lreki*«s of
a«ai ago 37. » re. I nrtcomeiktal Health
1 3i(l):36-a»
i»ce niMRS; mopsiES: Jirii; i
UOniDl; I.B3J1IC; CaOSmS; COBILT; |
CHOHItri; COPPIR; itOR; BI1CDBI: |
ntwa; aisusioa: uneivtSE; i
BVBIDrra; 1RI10BT; SCI (BIOS; f
snifin: TiTuioa: TIBIOIO*; zi«c; i
ecu: notin; iifn; UIMHS: i
CIBIBB11; CtBtBEUVR; HHBI; SDSC1IS; I
lucitis: siuEi; LUISS: icsti; i
BITIIS: COHIUTIVX zfunmovs; six; i
rcinsic fiiciciBE i
i
                                                                                                                                                                                              Ui
                                                                                         (HIT PIG!)

-------
Bagnesiva
7«3»-9S-a
Its 24.305, BP 651 C. BP 1100 C,  TO  1  aa  Bg at £21 C, 10 aa flg at 740
                                                                                       (CORIKIEV)
HSSflB
4168
Pane rets
«1«9
Spleen
4170
Teetb

BIPOSBBE gOUt




AIALTTICAl
HBTHOD
U
U
US

BOHBEB
or cisis
«> *
» 2
a) 5
b) 3
» 51
b) 10
) 10
) 26
) 11
O 51
I 10
> «8

BAIGS | Bill | GEIItll IIVOBIATIOI
1 1
1 1
1 1
a) 210*350 ag/g (vet »t) | a) 230 * or - 70 og/g | a) Biles
b) 260-320 og/g (vet vt) I (vet *t) I 1) resales
1 b) 290 * or - «2 ag/g I
1 (vet vt) | fro a a group of 61 autopsies,
I j ferensic aedical examinations, Japan
I ( tales, eeag age 00.6 yr. resales,
1 I Han age 37. • vr.
1 1
I i »>CE niRzns: ADTOPSIZS; JAPAI;
i i AioRiiDR: itsmc; caomna; COBALT;
I | CHOBIU5; CCCPEB; IBOI; REBC0BY;
1 i iiDim: msiisiDB: RAIGAIZSB;
I i BOBiDios; AniROii; SCIIDIOS;
1 i siLMWR: TIT AII DS; VAIABIOR; titic :
I | GOLD; BBOBI«I; IIT1B; KID1IIS;
1 | CIBBBBUB; CIBtBniOR: BE»BT; B03C1IS
1 i nicBEis: SPICT«: LORGS; *OITI:
1 1 BITUS; COIPU1TITS ET1LV1TIOIS; SEX;
1 1 FCB'ISIC BIBICUE
1 1
1 1
a) 120-560 ag/g (vet vt) I a) 230 » or - 190 I a) Bales
b) 65-580 ng/g (not vt) I ag/g (vet vt) I t) males
( b) 320 « or - 260 I
1 ag/g (vet vt) I ftoa a group of 61 autopsies,
1 | forensic sedical exaainations, Japan.
1 I Rales, aeaa ag« «0.t rr. rcaales,
1 | i«an age 37.4 vr.
1 1
1 | TB1CI fllRIHS; aMOPSIES; J»P»»;
I | IIOBH11; 15SBBIC: CIDSIUB; COBUT:
1 1 CGICRIUR; CCPPEB; 1B01; BEBC08T:
1 | IRBIHB: RiGirsiDi: aiienzsi;
1 1 IDBIDIM: HIIHOII; SCHDIBS:
1 1 SII!»I1B; TII11IOB; TalASIDR; ZIIC;
1 1 GCID: BBOBII!: tlTES; KIBHHIS:
1 1 CIBIB55S; CIBBBItDBt HE1BT; ROSCLIS;
I | S1ICBE1S: SPIZER; IDIGS; JOBT1;
1 | a!T»LS; COBPaUTiri ETH01TICBS; S!X;
1 i res-isic gzticzit
i i
) 2-5 mg/q | a) lot giren 1 a) Iiaael. rural area vita < 13 ag
) 2-3.7 sg/g I b) lot gireo I Hg/g soil
) 2.3-3.5 ag/9 | c) lot girea | t) Eaavel, rural area vith 13-19 ng
1 2.2-3.9 *g/g I i} lot given I ag/g soil
1 6.5-8.1 ag/g I e) 7.4 » or - 0.3 1 e) Znaael, coral area vith > 19 ag
I 6.8-9.1 ag/g I ag/g I Ig/g soil
1 7.2-11.1 ng/g | f) 8.8 * or - 0.2 1 d) Enaael. arban area
5.8-9.1 vg/g I sg/g I e) Dentine, as in (a)
1 g) 9.0 » or - 0.3 I f) Dentine, as in (b)
1 ag/g \ g) Dentine, as la (c)
1 h) 7. 1 » or - 0.2 | b) Dentine, as in (it
1 aq/g 1 Ktiiated fres graph (a-c)
I | Iqt dependent data also presented
1 1
1 I fesldeats in Finland
1 1
I i Tinuo: «st : sai; TEETH; COIPIMTITZ
I i !t«m-io»s: ueizsiin; zuc; SOBIL
I i mils: ntsii asiis: RETUS
I i
(IZXI PIG I)
BIRBIICK
Takava, H.
Sn-nki-TaEanoto, R.
Aaano, K.
Terai, R.
1980
Archives of
Envlronaental Health
35(1):36-aa
Takava, H.
Sa-aki-Tasnaoto, 9.
laano, K.
Terai, 8.
1980
Archives of
Environmental Health
35(1):36-aa
lappalainen, B.
Knaottila, R.
Salsinen, B.
1981
Archives of Oral
BlologT 26:1-6


-------
Btgouiai
J«W-»S-«
•»
Itl 24.30!. ST &S1 C. » 1100 e, f» 1 n H? «t «21 C,  1« •• Bg »t HO
                                                                                      (COITIIIED)
TISSUE |
:rj.



EIW3UIB WUTE
Ingestion



RCIBOD
US



OF CISIS
10



JM6S
•at jives



•Ell
9s, • or - 21 ng/aaT



6Eimi IITOHIUlai
IOM after aaanpplcaaatad intake of
2(4 aq/l«T. Data, Croc VT 1-0*7
•ipcrlnaatal periods.
nnlwrsltj students and eaploTevs, a
nar*e ml a teachac. InlUparoua,
ng*a 19-29 jr.
Rio^MBlti calanee cllqhtlv negative,
nfleetliq intae^itte Intake (60t of
•JI).
itmssti: OBHE: HOI; CIICIDR:
»i6iesiin: siriuiS: PiospBOBOS;
DIIK; I1IIEE11 BITlFailSS: PBISrilCT
tznitvcx
- -
lsh«, J.B.
Scbotiald, y.l.
6ran, R.I.
Inerlcaa Journal of
Clinical Intritlon


 II
 Itl St.«3BO, If 12M C. BP 2095 C, TP  1 aa Hg at  1292 C.  14 a« Ig at 1510 C
US SHI

«1T2
lorta
















*113
BlooJ




«1T«
Elood















EIPOSBB! 10DTE 1
1

















'























HJHTICIL |
BffTBOD |
„

















IIS





us
















•niBSR 1
or cisss
2

















60





a) 18
bj 20
O 25
dl «J













I1ISE

0.38-B. 86 ag/9 <*et «t)

















3.85-15.1 «4/l





a) Vot given
bj lot given
c) Fat given
d) tat glvca












(•EXT
mi

0.62 * or - 0.3« og/g
fv«t «t)
















9.93 + or - 2.25 «q/l





a) 0.96 og/100 al
b) 0. «5 ag/100 ll
-) > 1 U9/100 al
1) > 1 og/100 al
neilaaa











PJGI)
GEIFB1L IITOIUTIOI

Biles

Icon a grovp of 61 a«topsie«r
farensle nedlcal eianlnatlcns. Japan.
I ales, naan age H0.6 re. f«a«l«s.
•can aaa 37.4 Tr.

UICT amiTS: trropsiES; JIPII;
iioima: ntsnic; ciDani: COEE.TI
CtlORIOI; CCEPTtS; I BOS; BIBCOCI;
IltTUB; IMilESIDR; tHBlIZSE;
losioinj: iniion; scuuias:
SflHin; TITHIOII: TiaJDinn; n»c:
GCtC; B»R»l; LITEI; tIBlIIS;
CHtBBHI: CZIEBEUDI: HZUT; ID5C1IS:
piicn»is: siirs«; LOSS; loni;
BITU.3; COIT1MTITE ET1101TIOTS ; S!I;
fCHISIC BSIICIM
lo eorrelatien bef »n concentration
and age, aex, or anktnq.

B»altiT» nonfasting 15-83 ji olds.
E100S; BEHSUJIBIII SIT BODS;
iiieinsi; amis
a) tors liiiaq < 1 kn (con saelter
tl Gltls Uyl.q < 1 ka fro* suiter
c] Groan children
4) taral children
Htlaatsd (ten qrapk.

School-age chlldcen llilnq >aar Pb
stelt«c In Belgian. Controls tro«
raral and artan aceas.

niGimst; ciDiion; IBSEHIC; HSEIIC
CE1IKIC COBICUSDS; CBILOBEI;
IlIISTtTlL linOSPSJSIS; SHIITEBS:
"ITALS; BlOCt: DBISS; SE1GI3B;
PCPOtlTIOB IIPOSOBE; BOBJl IBE1S;
CBEII HESS

imaEscE

Tnkava, S.
SHnkl-lanvnoto, B.
laaao, K.
Terai, R.
1980
Irchlves of
Environmental Realtb
35(1] :3S-m










Pleban, P.I.
Cearsoa, K. B.
19T9
Clinical ChenlstCT
>s 15-191*

Sachet, J.p.
Boels. 3.
La over ra, I.
Eraau. f.
ClaeTS-Ibdrean, f.
lafantalne, 1.
Terdnrn. S.
1990
Ecvlronaental Eeseacch
22195-106








-------
faaaa
7«39-9«-5
•I
Itl SV.9380.
             IF 12»» C.  BP 2095 C.  TP 1  aa  B«  at  12*2 C.  10 ••  B« at 1510 C
                                                                                    (COItmiO)
Tissn
*1TS
Blood.
sens
»17S
Brala
•177
Brill
• 17»
Iteatk
»17» '
•tic
siposwj sotn



BkalatloD

laitmciL
BCHOD
us
>*
us
mi
us
i
nun
or USES
20

3

31
22
III6S
0.9«-2.92 19/1
•| 0.11-1. a 09/9 (Mt rt)
b) 0.42-1.1 ag/j (net *t
C| 0.0«-0.91 aj/9 (nt
¥t)
d| lot gir««
-
a) lot fflru
b) lot »iTe»
c) tot girt*
d) lot givei
•> lot 9ir«a
f) lot 9l«n
at given
lot giro
lot glTei
BEII i GEIEEU iiroBBMioi
i
1.82 * or - 0.6» 07/1 i 1C correlatloa betveea coDccctratlon
1 nt t$€, MX, or nokiB«.
1 Bcalthr. •oafutiog 15-83 jl o!4>.
| StCOB SEI1M; HMSTOlnlWT IRBO9S;
I tncmsi; RETUS
i
•I 0. S» » or - 0.27 | •) fil«, ccnbni, 9 a«bj«cts
*lutloiia, Japan.
ng/g (nt «t) I Bilas, •*•> 19* »o.« yr. r«ul«m,
j Maa aq« 37. a jr.
1 met ntims: IOTOPSIES; juu;
I HORinH: misnic: cinnirsi COBILT:
1 cfFOBitm: corrsB: isoi: HIKOIT:
I iioKrv; iieirsiVR: micirtsE;
1 «eBiniu5: iniBoir; scMoitn:
I stiEiiae: iitHim: miDiua.- n»c:
1 COLD: Bioiiii: LITEBJ KID»ITS:
1 CIBEBSfR: CEIE8E1£09: HBlSt; BOSCIES;
t EHCItlS; SPUEI: LOKS; 10BTI;
I imiS; CO»P»B1TIT1 ETtLOlTIOfS: SET;
I fClEfSIC 1HICI1E
I
1
a) 2S.S * or - 0.9 1 a) Slabni patlidas. 11 saapl«s,
aaoVg 1 cceffieloit af varlatioB (CT) 11. 9T
b) 2». a » or - 3.3 I r) Can late aocleas, 13 saaples, Ct
aaoV9 1 •'M*
e) 3«.a 4 or - 1.6 t c) PmtaMi, 12 saaples, CT 1«.5t
uol/g 1 1) Sibctaitla aiqra, 6 saipl«s, CT
a> 22.« « or - 2.0 1 21.71
aiol/9 1 «! Cerebral cortex. 15 saaples, CT
e) 15.8 • or - 1.8 t ««,5*
»oV9 1 d Rlppoeaipai, 9 aaaples. CT 35. OT
f> 32.8 » or - 3.8 1
aiol/9 1 Utopsj mples
»ry «t 1
SB 1 CIBEIBU. COEIEX: niSVIEBEn BKTHO5S;
I ciicnn: eoprzi; noi; iiisimsi:
1 EHIl: IBTOPSIK
3.0 a9 1 C 1 saapled at cat* of 1 I/a In. 2-10
1 ala after baraio? * are veldlag rots.
1 OltrecsltT pkfsics "bop. Florid*
1 F1CEI91; acnTS: 91I1TI: CIICIW;
1 CHtosMS: cnomi: copm: IBOI;
1 I»D: »«u»SE; ncxEi: POTISSWB;
l Sutra: Tninvi: TIIIDIBB; znc; IIB
1 FUinioi: rsBis: IIDISTIIU
1 IT90SPBSBK: TlaCE EISBIITS
1
) 0.83 ppa 1 a) learal*9 dl»afcl«d
1 0.58 ppa 1 b) Coitcel*
1
1 Ktraini) disable* a*d aorial 3rd aad
1 «tk 9cade atadeats 1* Canada.
1
1 cucin*; Baensim; portssioBs
1 scnun: oomi: coia»; copcEi;
1 TtOI; Itat: RtKinSSl MIC;
1 cttoMQ*: Limvn BncniT; BCTILS;
l mil ntimi; CH»D»
RFCEEICE
Pletai. P.I.
pearsoi. K.B.
1»7»
Cllaleal Chealstrr
25(11J s«»5-1918
Tnkata, B.
Saxakl-Tanaoto, K.
laa«o, E.
Terai. a.
1980
trcairee of
EavlronMatal Health
35 (tt : 3«-««
Goldberg. «.J.
illea, I.
1991
ClUleal Cbealstrr
27(a):S«2-56«
"
ftksals»0n. K.E.
)esaedeleer. G.G.
Johansson, I.B.
BlK!hest«r, J. ».
197«
lanals of Ocenpatlonal
Rfgleae 19:225-23*
Plbl, B.o.
Parkas, B.
1»T!
Scleace
198(«313) :20*-206
                                                                                                                                                                                       VO
                                                                                                                                                                                       00
                                                                                   inn

-------
1«39-9«-S
II
It! 5*.*3*0. BP 12** C, BP 2095 c. IP 1 aa
                                              at  1292  C.  10 •• 84 at 1510 c
                                                                                       (COITXmiD]
nssci
41*0
Bair
»181
Itir
*1«
lair
iKsnn Borex



iiunxcit
BKHOD

U
U
IOHBBB
OF CUBS

al 38
b) 2*
O 37
1) 2*
•1 16
a w
*) 23
b) 19
o «2 a>
1*
•} 26
O *0
11KB

•) lot 4iT«a
b) lot gin*
c) lot qirtB
4) lot 4ima
•) lot giTe»
f) lot giTeo
a) 0.030-2.663 «4/g
b) 0.156-3.72* «g/4
C) 0.030-3.72* 14/4
a) 0.123-*.901 vg/g
•) 0.038- 1«. 330 B4/9
f) 0.018-16.330 og/q
mi | GEIBBIL IimiHIOI
1
1
| le*l««. 2* represcatatlf*
1 Fce-aaalyflta treatveata ara
I tabilatei. Tk* f«sibililr of a
I aollatic, m«-«aak poltcT foe h«.lr
I iiilT«i« la mtllMfl aai «ipport«d.
1 cirtn; -ttKt VLtmtn-. ins;
| ITSTJU.Il: BIlSmiBlR BCTBOnS;
I anus; pBOTins; COIPIUTITZ
1 ninitio»s: UBnm: MTIMII:
I itsnic; Bi«wi; Bionre: CIOTIOB;
| C11C1VBJ CnOtllZ; CB1OBIBB! COB11T;
1 ccmi: siiLTUB; g/4 | c) 111 eoitccl*
1) 0.279 og/4 | 1) Blla loltipla Kl«eo*i« patients
•) 0. *6< ng/q | •] r«Ml« »ltlpl« Klcroslc patlaata
() 0.403 14/4 t f) 111 Mltlfl* Klacoti* patlaita
italiaas | Sa«pl«« froa 7 scalp sites in «ack
1 cabjKt.
I cum: iDoiTS: CBITHI nitons
I STSIEB nsiisBt mi; tionni:
1 ««cmi-. ciicniB: cnoilii; cop>n:
I envt IOPIIB: m«s»itsi; anus;
I snnm; suns; SODIBII; SHFTH;
| 1111B11V, T11C
i
BRBZfCX
Ckittlcbocoagh, G.
1980
Scl«aca of the Total
EvTiroamBt «:53-T5
eibcoB. E.s.
Omolta. B.S.
19BO
Ivtritloa Baports
IntAnatlocal
21 (3) : 3*1-3*9
Bjan, D.I,
Rolzbacher, J.
Stnart, o.c.
1978
Cllalcal Cheatstrr
2* (1H -.1996-2000
(HIT MCI)
                                                                                                                                                                                              \D

-------
Raigaoese
7*.21-*«-5
Be
»tf 5*.*3«0, SP 12«« C. BP 2095 C. TP  1 » Hg at  1292 C,  ID  » Hg it 1510 C
                                                                                      (C01TUOED)
TISSVE

*1»3
Heart


















• 1«
KUaer

















• 185
KUaeT






















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am men
BRBOD
U



















I*


















•1























roam
OF CaSSS
a) *
b) 2


















M ^
b| 2

















1 8
1 »
c| 10





















SJ1CB

a) 0. 26-0.11 ng/g (vet
*t)
b) 0.52-1.4 og/g (vet «t

















•) 0.21-1.0 og/g [»«t vt)
b) 0.43-0.63 «g/g (vet
•t)
















) 0.050-0.85 eg/g
) 0.0050-3.62 »g/g
> 0.013-1. 7» ag/ij
fet rt




















111) | GEKRU IIFOSR1TIOK
j
1
t) 0.33 » or - 0.06 | at Sales
aq/g (vet vt) 4 t} Feaales
b) 0.96 » or - 0.62 |
ag/g (vet vt). | Fro* i group of 41 autopsies.
1 forensic vedlcal examinations, Japan
1 ealts, MID age »0.6 rr. Feiales,
1 a«aB ag« 37.4 TI.
1
1 T»cr BtBBBBIS; 1UTOPSII5; jiPltr;
I I1DBIIB9; »»S!«IC; CIBSIDB; COBU.T:
I C BROS 111 t CCPP1B: 1801; IEKUBT;
| I1DIHH; (IlGICtSIOS; MIGtffESE:
| SIBIDIHJ; UTIBOII; SCHDIOfl;
| SILIlin; TIIUIOK; TIHDIOB; ZI«C:
| COLD; BBOBIHE; III ft: KIDIZTS;
| CIEIESHJ; C18EBEILOB; HEIST; BDSCLES;
1 farcins; SPIEBB: LOBCS; lOBTi:
| *IT11S: CORPtBlTITS STUItaTIOISj SIX;
I TCBIISIC REtKHE
1
a) 0.76 * or - 0.28 | a) Bales
«9/ males
b) 0.73 « or - 0.1* (
«4/9 («et vt) | Itoi a qroop of 61 autopsies.
| foc«*slc eedieal axa»lnatlo»i, Japan.
j Bales, Bean age «0.« Tt. Females,
I Han aqe 37.4 fr.
1
1 1B1CI tXIRins: aOTOPStiS; JaP»;
I iiOBinm; aEsnic: ciDsioa: COEUT:
i ce«o«iatf; catttti teats itttcasr:
I IIDIH1; gaSIISIOl: ItlGlHZSI;
I toinn*: IITIBOII; SCIIDITIB;
I SILIIinS; TIT1IIOI; TalUItfg; 3IBCJ
1 GCID; RIORIII; IHEB; !tID»BIS:
1 CIBIBSnif; CZ1EBEUOI; B31II; RDSCLES:
1 PlfCIElS; SPIEZ1: LTJPGS; IOBTI;
I RtTaLS; CORPallTITE ETUKaTIClS; SET;
| ICKISIC HZDICIIE
a} 0.073 19/9 1 <) Coitrola
b) 0.073 a?/g 1 I) vorkec group I
O 0. 076 ug/g | c) Vorkec gcoap II
«et vt 1
elians I Ceceasei ret luerr a«d shelter
1 tetkets, aget S5-7S rr. exposed to
1 tearr tetals 1-3 tecaies. Ilae
1 tctiem retlraaeit aM death 0-1.5 rr
1 It group I aai 2-19 ji, group II.
1 Coatrols, ages «3-72 re, vbo lited SO
1 ka (ros tie factory. Svedei.
1
1 SHIM: CafiaTBRS; KIMITS; 11*31:
1 tEiGs: coRpitHira EnLoiiiois:
1 IIIIISTCIat ITGIEIEi 1JISOEIHBIT
I BIT BODS; iniBOIT: atSElIC: CISRIOB;
1 CfSni; CBICBtVR; COB1LT; COPPJB:
1 cent: isoi; iuwtMin: isic;
1 eiiSMiss: ancoiT; HOITBDEIOR:
1 IECSPBOSOS; BTOIDHJ1: SCHDIOT:
I £itEnn: snr-s; TI»: TOIGSTEI;
1 ZIIC; 9!11TB HIEIEDS: IIDDSTBIll
t PtinS; SREimS; TEllVSXOH
1
EER1BDCI

Tukan, 15.
Snuki-Iasoaoto, B.
Aaano^ K.
Terai, R.
mo
Irchires of
EnvicoBaeatal Health
35(1):36-«»












Takava, R.
Samkl-Iasuioto, R.
Itano, K.
Terai, B.
I960
Irchires of
EnTironaeDtal Health
35(1); 36-**











iraae, 0.
Vordbecg, 6.
vester. P.O.
1980
Science of the Total
EBTltOBient 16:13-35


















ilKT Past)
                                                                                                                                                                                          N5
                                                                                                                                                                                          O
                                                                                                                                                                                          O

-------
BiagaMM
7«9-«-5
Si
Itl 5«.«3M,
1«« C, Bi 2095 C, W 1 » If at 1292 C, 10 u Ig at 1510 C
                                                                                     (COITIIOEM
1ISS01

•us
Kidney











• UT
lifer

















»188
Li tec




















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liiar










EIPOSUIE BOTH

novation




















































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IBUTTXCU
IHBOD












n


















11

































IDBBEB
a; cists












at 11
b) 3

















a) «
b) 9
O 10































BMSE













a) lot given
b) 0.96-2.3 uq/9 («et >t>

















a) 0.017-2.18 19/9
b) 0.07S-2.9". 13/4
c) 0.06t-2. 26 ag/4
«et vt






























SEil | GEimi IlrOBMTIOS
1
1 feTle*. Profile «f lealttT subjects.
1 Baseline data for determining ehuaes
I in Batritiaml st«t« fro. industcial
1 fcod processing techniques.
1
I in ZSILIIE; UUIT5; PSTDE; nrurtS;
1 EIOOP SEBHH; HUB; KIDRTS; UTIt;
I HLIti ISTIH: DIITS; FOODS; SOUS;
| TIGR1TIOI; CUHIOT: COVPIB;
I BKGjiisi: inns: TB»CE zinnTS;
I ZIIC
i
1
>.) 1.T * or - t.& ( »1 Bal«s
uq/g l»et »t| 1 l\ Mi«l*i
b) 1.5 » or - D.B8 4
ng/9 (»et »t) 1 Tcoi a eaa *qe «0.6 jr. paiales.
1 Man aqe 37.1 Tt.
1
1 mci niBins; itrropsiis: JIPII;
I iltJilian; usmc; ciDUtn; coant:
1 CBBCBIUS; coEPtE: 1BOI; aiBcuai:
I iiciuB; sicitsioB: IU&IIISE;
I BdEIlini; (ITIIOBT: 3CHDIUB;
I sninttg; TiiMioa: miDitu: z»c;
I GCIE: BlOmt; Lit IB; KIDI1TS;
1 CIBMIUB; CtEIBEllH; II1BT; 10SCLIS;
t IHCIItS; SPLEII; LOKS; JOBIi:
| IR11S; COIfiBlTin ETUTHIIOIS; SH;
| TOinSIC BIEICIII
1
a) 0.11 ag/g I <| COfttcall
b) O.'O I9/-9 | t) lorter  group It.
1 Controls. >?eB «3-72 yr, vko lived 50
1 k« fton tbe tactocj. sveieii.
I stnn; ciciTHB: tiiwiis: HUB:
t lines; comuTin ETHBITIOIS:
I IIinSTBIll HTGIBI!; B!lSD8Htn
1 tmaos; trnsoBT; USHIC; ciositja;
1 CISIOR; cmtoeiai; COBILT; COPPIB;
l ecu; IBOICJ urrmoB; LIID;
1 BI1GHISI; 11BCDBT; BOlTBDnOT;
I iBospaons; BOBions; sci»Bim:
1 siitnan: SIITEB; TI»; roiosru:
1 tne; siuig BiziSTJs: itDosnui
I EE1RS; SBIIIBBS; II1HJBIH1I
1 t«fte«. Tcotile at h«<b7 mtiject*.
1 Eascline data foe deteraiaing changes
I In iatcitio»l stites froa liliatcial
1 fcod processing techniques.
1
I in lEiuii: uaits; rnrus; nrans;
I eiOOO SBHOB; BilE; KIDIITS: tHIB;
1 Bill; IITIEI; JIITS: FOODS: SOUS;
1 uenuioi: ciDBim; COPPE1;
1 mansE: inns: TBUE Eiznris;
1 UK
1
BEIEBBICI

Gatkrle, B.E.
Boblnaoa, B.r.
1»7»
•e* Zealand Bedical
Journal i7 (603): 3-8








Takara. 1.
Sazuki-taxanoto. 9.
Inno, X.
Teral, H.
mo
Iccbiies of
InTlconnental Be*ltt
35(1|:JS-44











Bcnne. B.
•ardbeci, S.
fester, P.O.
1480
Science of the Total
EnTiEoment 16; 13-35
















Gntfarie. B.E.
Eobinson. B.r.
1»7I
lev Zealand gedical
Journal S1(S03):J-8







(HIT SISB)

-------
m S«.»3»a, IP 12M C, BP 209$ C. It 1 n tg at  1292 C,  10  M B« at 1S10 C
                                                                                      (OORIIOBD)
tissis
• 190
l»9
• Ifl
l»«q
«m
lilk
Bxpostn ion


IIIITTICIL
BRM0
U
It
latest loa
•ram
w cuts
•) 2
14 2
•1 •
tt 9
c| 10

I1KI
•) 0.39-0.68 «j/j (net
•t)
D) 9.09-0. 76 «j/g (««t
•t)
a) O.Ott-O.tl ««w
b) 0.0015-0.60 19/9
c) 0.00 70- a, 31 *g/g
let «t

•MI i etitui IIPOBUTXOI t nnsnici
t 1
i i
i i
«) 0.5* * or - 0.21 1 «l Ida 1 Tifcam, I.
ooyg (net »t) | t) r«nles I Snaki-Tasuoto, 1.
b) 0.«3 * or - 0.47 | | IUBO, I.
•9/9 (««t «t) | »co« * ?ro»p of f 1 »tep>le«, t T«r«l, s.
1 famatc w41nl «»laatlou, Japan. 1 1*80
I lalM. Han tg» »0. t re. F«Ml of
I •«•> •«• 37.* TC. | CavicouHtal E««ltb
1 1 35(1|:3*-M
I T»CC ntiziis; unotstsst ami; i
1 ttvnnf; Msnic; CIDSIUS: COMLT; i
1 cnoitivi; coFRi: in»; aiicsiT; I
i mm: IISIBUIJ uvenisi; i
I imoiDi; union; scmm; i
1 siinmi; tniiiaB; uuoioR: me: I
I eotot stosni: IITBU tmiiis: i
I ciimmi: c»niu.«ii inn: BOSO.ES: i
I limits; spiEBi; lotss: totrti i
t StTHS; COWlUnR (TUB1IZOS; SFI; I
1 ictnsic IUICIIB i
i i
I i
a) 0.054 wg 1 •) CMtcol* 1 Brail*, D.
b) 0,029 ag/g 1 t) lort«c elt«r 1 Scl«*e« of the Total
I >crt«r«, a4«* 55-76 rr, azpoMd to I JiTltoMant 16:13-35
1 l«ar? Mtals 1-3 tect&as. Ill* I
1 t U-72 ye, »bo lived SO I
1 ki ftoa the factory. S»ad«n. |
1 1
t SIEBSI: cttims; riBtiTs; iirn; i
| IOI6S; COIHMTIVI XTltUTIOIS; I
I IltlSTIIlL BTSIBIS: RtSniEBZIT 1
1 IfTBODS; IITIBOIIJ USKIC; C1DHVI; 1
I cisni: cnonvi; COBUT: COPFSI; i
I GciD; itoi: iiirnna: iitB; i
I Misirasz; incoiT; (rairBotxff: i
I ttostamas} iraroiTS: sciiBimr.- i
i snmrat SIITCT.- i»; mesni; i
( IIIC: IMlTf HIIIPS: KDOSTBItl I
I pitits: siftms; Tsiiouoa i
i i
1 »•«!•*. Profile of aealth? najeetc. r ectkrle, B.B.
1 I»«liie data for feteniale? cbU4«> I tobiuoa, n.T.
\ la ntcltloal «tit« fcoi iadwtrlal | 1978
1 food ftoct**i*a tockrlqves. I Wen Sealaad Sedlcal
I 1 Joanal »7 (603): 3-8
1 in XBUiit: IBIITS: rrrus; nrtns; i
I BIOCD sini; nit: noins: LITBI: I
I mi: mm: Dim: FOODS: SOILS : t
| •HR1TIOI; C10IMB: CO»PEB; 1
1 tiietnsi: mils: ntci HtERzns; i
1 TIK 1
« 1
lint us 8)
                                                                                                                                                                                         NJ
                                                                                                                                                                                         O

-------
7»39-9«-5
II
It! 5«.93*0, flt 12*1 C, B* 2095 C. W 1 •• Bg at 1292 C. 10  M  Bg at  1510 C
                                                                                      (CORI(IED)
IISSBI

4191
BMCl*

















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cerl












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ntaoo
11










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or USES
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» 2

















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W 1
cj 1












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a) Bot glTia
b) lot glrei

















a) lot glvea
•b) 2.0-2.1 eg/g (Mt «t)

















a] lot applicable
b) But applicable
cj lot applicable











(IIX1
	 BMB 	

a) 0.28 * or - 0.21
•g/g (Mt «t)
b> 0.33 * or - 0.29
ig/g (net ttj















a) O.«1 « or - 0.37
•g/g (Mt «t)
b) 2. 1 » or - 0.07
•g/g (»t rt)















a) 72.3 eg/g
b) 132.2 ag/g
c» 1*.3 eg/g
Drr «t










VIC1I
SBI1B11 IBfOIfliTIOI

a) Bale*
r) femlei

ftat a groip at »1 titopilec.
foreaele Mlical exaalaatloae, Japan.
Bales, aeaa age «0.t 71. Ttaalo.
aeaa age 37.* rr.

iitci niBtits; imontxs: mai:
iivnioi; amtic: CIOBIOB: CDBU.T;
cnOBMB: CCfMI; I«01; BBICOIt;
IIDXOI; BtfillSlOB; BIIGIBBSI;
lOflDIOB: llHBOITi SC1IDIVB;
snimi; TRiiioB; nuDXOBj cttc;
soiB; Biotiit: inn: HDIHS;
cnmni: cnnnxn: m«t: RDSCIBS;
siicius: semi; towssj ioni;
anus: COIPUITXTB ETIIOITIOBS; sn:
fCCIBSXC BStKIlI
a) lales
t) reaale*

Froi a groap of C1 aetepcle*.
f emslc aeJical eualnatlou. Japao.
Balei. eeaa age M. C rr. Feaales,
•eai age 37.* ft.
•
Hici niBins; amoFmsi Jim;
nanin: MSBBXC: CIDBIHII COBU.T:
CHCBXDI; CQina; KOI; BBBCqst;
IICID1; BieitSIOB: UIUIESI;
BQVIDXBii: aiTXBOBT; SCllDXOt;
sntinai TiuBioa; nnoxoi; zxic;
CCIB; BtOBIlt: IXTBt: IXDIBTSi
ciitBBin: czimuai; IXUT; tasciss:
I1ICIBU; StllBli IOB5S; IO1H:
IITILS; COBPUlflTB ITllVinOIS: SIX]
retnnc aniciiB
•1 aetoc Mitm alataie patleat
t) Botor Miroa dlmeee patleat
c) Control
Teatral bera tlane, aMopai
lo ietectable Ba la 5 otter patleat*
aad 11 eoatrel*
fatleats aied of arotrophlc lateral
•eleroil*. a) age 59 rr aaa b) <9 rr.
Ccttcol, age M TC, U«A ftea Ing
catclBoaa.
THIS; IDUITS; tOTOtSISS;
I'dtOHISCfltlB OISnSBS; SflML CO1D;
tiokccnaBiHioi; citcma: COPPBC
IIGI; LI1D; BlISallSBi BRI1S;
sitnnas UK

IBRUICI

Telcava, B.
Snaki-Ta*aaoto, B.
laaao, 1.
Tetal. H.
1980
krcalTe* ol
CaTlroa«atal Health
35(1) :]«-«•











T«k.a«a. B.
Svzakl-Taaaaoto, B.
laaao. X.
Teral. B.
1980
ircalTe* of
Enrlronaental Health
35 (1) : 3«-««











Eirluder, 1. 1.
Mttea, B.a.
1979
lends of learologr











                                                                                                                                                                                            NJ
                                                                                                                                                                                            O
                                                                                                                                                                                            Ul

-------
  langaaesa
  7«3»-«-5
  IB
  Itf !». 93BO, IP 12** c, 8P 2095 C,  TP 1  aa Hg at 1292 C. 10 u Bg at IS 10 C
                                                                                         (CORIIUSD)
IISSIX



»19«
StlMB



















«197
arin«
















EIPOSOSS BOOTI










































IIUTTICIL
IRIOD


H




















US

















man
OF casss


») 5
b| 3



















at 17
b| 15
o 16
d) 7
e) 21
I) 23












a»6E



a) lot given
b) lot given



















a) lot gi»«l
b) Rot jlv««
c) lot given
d) »ot given
a) lot gives
J) lot given












sua i esituL irannnoi
1
1
1
«) 0.1« * oc - 0.26 1 a| 1tl«s
•9/9 (oat «t) | C) resales
b) 11 » or - 9.2 ug/g I
(••t wt] 1 *Toi • groap of 61 autopsies.
j forensic sedical exaBinatioa*. Japan.
I Balm, man age »0-6 jr. Pesales.
1 Mai age 37. 1 vr.
1
| T11CI BIEBEITS; (ITOPSIBS; J1P1I;
1 «ic«irj«: nsETic; CIDHIOB; COBJIT:
1 cBnoann: COPPBB: IBO»: HEICOBT;
| IIDIVB; lUItSKTB: RU61IISE;
1 mBiDwa: iniioR: sc*roioR:
1 SILEHUB: TllUItn; T1UDIOI: ZITC;
I GCLD: BIOBIK; tlTEt; KIDIEYS:
I cisiBis): citEBCiLirg: HHBT: snsctss;
1 EiicBiis: sciBEi; Lines : loni:
I IRalS; COBPIB4TITJ ETUDITIOIS: SKI;
1 fOBMSIC BEEICIIE
1
1
a) 0.95 og/9 I a| Boys lltiof < 1 ki froa aaeltet
creattniBe t fe) Sirls liviog < 1 In froa saelter
b) 0.60 ag/g | c) Orbaa boys
craattaioa 1 9) Vrtai qirls
c) 0.80 ng/
-------
Bcrcurr
7O»-»7-6
Bq
lt» 200.59. IP -38.87 C. BP 356.72 c. »P  2115(8-3)  aa Bg at 25 C, 100 an 89 at 260 C
                                                                                       (CQItllVSD)
TISSUE

«»*
Biooa
















• 200
Blood






• 201
Blood












4203
Blood,
seres








BIPOSIM tone

Injectloa
















lagestion







lagestioa
Inhalation












lagestioa










lltLYTICll
BETB09
US
















US







•1























BOBEIE
OF CASES
6
















339







a) «
B) 3
O «











1










B1BSB

a) lot applicable
b) lot applicable
c) 3.6-19.3 ng/nl















10-167 ng/g







a) 1.6-17.3 ng/g
b) 3.7-8.5 ng/g
c) 0.6-a.a ag/g
Freak «t










*) lot applicable
b] lot applicable









U1B

a) 17.7 ng/nl
b) 8.0 ag/al
c) lot gifen














-
tot given







a) 5.9 ag/g
b) 5.3 ag/g
c) 2.9 ng/»
Fresh vt










a) 115 ng/100 al
b) 10 eg/100 nl









6IIEB11 mOMUTlOB

a) liter 0.6 al/kq of gaaaaglobalin,
1 patleat as in a|
I) • iik after gaacoglobolii aed
C-penicillaniM (2 gn/day) . 1 patient
c) 5 patieats

2C yr old receiving gannaglobnlia.
containing 0.01t •erthiolate (50.3 ng
Bc/al). leceiveft «o-50 ng Bg/yr.
ether patients receiving 0.6 nl/kg
«»«y 2-3 rt, no Bg sensltlvitr.
Pink, sealing, preritic palas and
•olea. flashed cheeks, photophobia.
irritability, treaor, altered
sensation it fingertips, slomd nerve
coadactlon velocity.
BIICBIY; BHUS: SLOOO; TOIW; BUll
PCISOIH5: BISSISTS; BSDO TBESlPT
Ktlaated ficn graph.

Ontario Indian «ho at* coataninated
fish.

I1CCD; BIIB: BIBCOST; HETtlS; CMtDl;
TOPIUTtOI BIPOSVSB; FISBBS; DIZTS

a) CceapatlonallT exposed
fc) In etposed area
c) Snrgical ratieats

Tegoslariaas, ages 1*-63 ji.
latapsies of at and b) .

IIDflSTBIll POLL0TIOI; OCCOHTIOBU
iinsDS: POPVUIIOI nvosmi;
S01GEHT: BBiCUBI; RBBCOIT OBSW1C
coaponos: TOSOSUTII; imopsiis;
HOOD; Blim; KIDBBTS; UTIB; 10ISS;
1D5CL1S! SP1ZBI; THYROID GlliBS

a) It adaissioa
b) 1 no after dinereaprol therapy
Dose, «30 ng nercuric chloride

5 ji old Beiicaa-incxlcan.
ictonlul tain, malting, bloodj
stool.
Icite reaal failure
HOOD SEBDB; HIBCOET; HTTHS;
CBIIDXII; BIT11 POISOIIBG; CIS!
EIS10IIBS
(BBJI P1BZ1 ~ ~ 	
KFIBIiCI

Batheson, S.S.
Clarkson. T.».
eelfaat, E.8.
1*80
Joaraal of Pediatrics
97(1)s1S3-1S5












Phelps, S.I.
Clarksoa, T.H.
Kershav, I.G.
Wheatley. B.
1980
Irchives of
Environmental Health
35 (3): 161-168 .
Itosta, L.
Zelcako. T.
Bavnik, T.
levstek, B.
Dernelj. B.
Byrne, I.B.
im
Coaparative stadies of
Tool anl Invironneatal
Coataalnation.
Proceedings of a
Synpoaion held in
Otanienl. Finland.
lagnst 27-31. W73
Seiael, J.
1980
Pediatrics
6«(1t: 132-13*








                                                                                                                                                                                              NJ
                                                                                                                                                                                              O

-------
7«9-«7-«
B*
111 209.SI. tf -38.*? c. »  3S«.72 C, T» 2110(c-3) aa Hg »t 25 C, 100 « Bg «t 260 C
                                                                                       (CORIBinSD)
1XSSSE
«203
mi>
»zw
Bill*
«2«
Brail
«20C
iraia
Bifosm ton

Xagestioa
laaalatioa
lageatiOa
akalatiea
lUimclI
•ROOD
•1
U
sc

IDBB1S
or CUES

•) s
bj «
9

IHCB
a) < or - 7.* ug/g (»»t
«t|
b) < or - 3.1 119/4 (wet
"t>
C) < or - 9.3 «g/g (*«t
«)
d) 1.1-3.0 119/9 (wt «t
a) 181-I3C7 ag/g
b) 15-«1 ag/g,
Fresh »t
1
'
._
SO. 1-2*7. 1 ag/g frest .t
lot applicable
BE** | GEtiiiL iiFotauioii I Birstncz
I I
I i
a) 1.9 * or - 2.C 1 •) Rales, ceiebraa, * subjects 1 Yvkava, B.
•9/4 (»et vt( 1 *J resales, cerebraa, * sabjects 1 Sazaki-Tastaoto, B.
b) 1.2 * or - 1.5 1=1 Bales, c«rebellaa, C subject! I laaao, R.
ug/g (»«t wt) I ') f«a»l»«, cvrctxllna. • aab]*eta 1 T«r»l, B.
c) 3.3 » or - 3.3 1 1 1980
'9/9 !••* >t) I Txoa a gro>r of f1 antopalva, I lrehi«*s of
4) 2.2 » or - 0.9 i toravlc a»dlcal •xanlaatioa*> 'apaa. 1 5BTlron««atal Eaalth
ag/9 (>«t *t) I Ralca, Mai •«• iO.C rr. P«aal«8, I 3S(1|:36-M
| MH a«« 37.* Tt- 1
I HIM niciins; inoniKi j»ni; i
I imnroBj itscnc; CIDSIDB: COBUX; i
i cnoiioK; COPPTI; IMC HICOII; i
1 linn: ainssim; msinsEj i
I coixravi; iBixton; sciiDin; i
| H1EIIBS; TITlTIali TlIlDIdl: IIBC; I
1 eciOi Btoiini: IITXI; nvins: i
I C»ZB(irt: CI1RBUOR; HURT; HDSCIES; I
1 i items ; spini: ittss; writs i
I RR113: COBPU1TITE tT»L01TIC»S; SEX; 1
I FOlItS 1C BIDICIM 1
I 1
a) 1654 ng/g I a) occapatioaall; flfos»S \ Koata. 1.
b) S3 ag/g 1 t>) la «iposti) arc* 1 Sclmko, T.
rrash »t | 1 Earaifc, T.
I l«topsi«s, TngoaltwiMis, ages 19-75 f t«TSt*k. ».
I jr. 1 D«ra«l], E.
1 1 Brne, I.B.
1 IlDDSTlIlI PCL1DIIO1: OCCOP«rtO»ll | 197*
1 BIZMDS; POPOUTIOS nPOSOBZ; I coiparatln stadias of
1 snaiBT; HIBcnii HSICDir CISIIIC 1 Food «»d Ia*lroaaeatal
1 CCBPOOIDS: TOSOSUTIl: inTOPSIKS: 1 contaaination.
1 B10OD: Btlll; KIOIETS; L1I1B; LOISS; t Proceedings of a
| ROSCLES; SPltn: TBTSOID Sums I SyipoBina beld la
I 1 otaaieai, rinlanil,
I 1 »»0.5 ppa total Bg I Saitfc. J.c.
1 1 1»81
j Caaallaa ladiaas, aertanest Oatarlo 1 Joaraal at Inalytiesl
I | Tozloolog; 5:90-9S
I TISilS; toot COITHIUTIOR: I
1 ncusTtni rcLiimoi: POPOIHIOI i
1 [tposnti: itnii UEIS; BSBJI uus; I
I >nn poitmo*: aEBCDBT; BESCOBT i
I c«si«tc coapcnios: Httn: Mmsis; i
f IITEB: menu; SPLEEI; CIIIDI; i
| IROPStVS |
i i
1 i
.9 ag/g | MtopiTr 7 ac oil girl exposed to 1 Beatlako, H.I.
I vapor. >A. 1 Toapklns. l.L.
I I Soclaad. T.*.
I Peter, Toaltlag, pallor aafl dyspaei, I Baasoa, B.B.
| Colloved sevca days later by apoea. I Jactsos. a.B.
I tllateral paeaeotlorax, seTere I 1981
I acidosisff coaaf selzarer aad .death. j Aaericaa Joaraal of
I | Diseases of Ctildrea
I Parti*! ateltctasls vitk s.alliig. | l3S(t):«2-M
1 fecal atynleal hrperplasia, »ad I
1 l«qmantici of cells of alfeoli, j
1 alveolar daets, aad bronchioles. f
1 Byaliae acatcaaai, aad Latra-*lveolti j
1 aeaorraages observed. Oeg««rative 1
I chaages la illB«T«. diMase fatty 1
1 ctaeges ia liver. I
1 1
I HISSlCinSlTIJl 40TOTSIIS; CUE 1
I Bisioms; iipins: RSTII toisonte; i
1 tiiii; icitius: tun: LOBES: i
t incoit: must iiinmo* i
t i
(HIT »»6I)
                                                                                                                                                                                              NJ
                                                                                                                                                                                              o
                                                                                                                                                                                              ON

-------
Mtcirr
7*3»-97-«

•1
It* 200.59, V -38.87 C, B» 354.72 C,  »» 2110(1-3) u Bj at 25 C. 100 •• l« «t 2CO C
                                                                                   (CORIIBZD)
1ISSBI

»2«7
lair










«joe
lair

















•209
lair













1210
Bait















inosmi VOTOB































IikalaUoa
P*rwl





























kiumcu.
anioD
us





























»













us
















10BBX3
or cisss
B| 31
b] 22




























2













2,32*
















•1ICI

*) «0t glTII
b) lot 4iT«*




























•) lot 9l*«
b) lot gi»«a
c) lot girti
S) lot gi*«











*} 0.2*-2J.a* ppi
b) lot giiaa
e) lot gi»aa
1] lot glTan
•) lot 9! TIB
f) lot giiaa
g) lot gif«B











nai i cmm nrotuTxoi
i
a) 1» ppi | •) l**i*l*g dlsatl«d
b) IS ppa I k| COBtral*
1

1 *tb arad* 0t*d*its is c*&ada.
1
I ciicivi: i»6Rsioi; POTissiOB;
I SCBHB-. C It BIM-. COBU.T; COMBS:
I IMI; MID; nieinsB; mcj
i cnogin; insioi! IBICVIT; anus;
1 Bill: CSItltlll: ClllDl
i

1 t*fc«lat*t. Ib* f*astbllltT of a
1 belittle, io-«sk policf for hair
1 aialTiU It oitllMd a*4 s*pport*jt.
I nnti; met ntnttsi uii;
I IVSTlUIl: BJaSTIlMIIT HCTBODS:
I iniis; ptornis: cwMtinn
I ITllVkTIOIS; atOallOB; aiTIMIT;
I usiiict itinit nonii: citina-.
1 ciiciui: ciieuii: craonoB: COEIII;
I ccjMt; c ill MB: enunni: eou>;
1 UBiiit IMI: tiRBkvn: nit;
I iintsni: MNinsi; BBSCVH;
I miionoii iicrn; PBOSPHOIBS:
1 fctissni: SOTiura: SEIIIIDI:
I miooi; sitmt SODIHB: siionm:
i snroi; TII: iii»iio«: TOKSIBI;
| ZIIC; HKC11BB
i
a) 181 ppa 1 a) Cas* 1 - k*ad kale
b) 11.9 ppi 1 c) Cas* 2 - »«d kalr
c) 16.8 ppi 1 c| Cas* 1 - pabic kalr
d) 9.*» ppi |d) Cas* 2 - r«ble kalr
1 (cat l*T*ls
1
1 Bntlsts, •» and SO yr old.
1
1 Tlio«T ttaaor, final OstviloratlOB,
t imr BMiorr, IrcltabllitT, k«daek*a.
I Baicl* palaa. anonila, nlgkt loss.
1 lieoordliatloi at llibs, Daam,
1 tipkorU.
1
I scoiuio; Kin nisoinej BUI;
l inis; siBcniii mils: OCCDIITIOHI
1 IUIIDS; SBOKItG; DIFIISTtl
1
a) 2.19 ppi | •) l*sld*Bts of Sklkoki, ial« and
b) 1.48 ppi | Ciaal*, all a»w, 1>75-1 »7«
c) H3 ppi | b) 7-9 rr old ial*s
4) t.W ppi | c) 7-9 Tr old fnaln
e) 1.*2 ppi I d) 1*-1S TT old ial*B •) 1»-15 Tr old
f) 2.83 ppi | fcialaa
q) 1.60 ppa | f) 20-10 rc eld *al«a q) 20-a« jr old
GeoMtrlc mau I t«aal*s
1 t)-g) nsldcrts of Tokisfclia
1 rr*f*etaca, 1977
1 lgrle*lt«r*l area of Tokickia*. Japan
1 >b*r* Bg eoBtailiatloa Is l*m than
I «1amk*t*> OB the Ixlaad.
1
1 Jmt; attoltscEITl: » DOLTS: |«I;
I cntnn: six; Biit: ro»oi.inoi
1 IIPOSDH; BlICTIT
1
•nnnci

riki, i.e.
tart*!, g.
1977
Seine*








— — — — _____ _
Chittl«boroagli, s.
1989
Sdme* of tk* total
lailtoaaalt la: 53-75















Sriiagton, I.S.
Cross, J.D.
Dala, I.B.
Lcnikan, J.B.I.
1980
Jeorial of the Sociatj
of Occupational
Badleli* 30:37-39








SUioima, S.
Kinca, a.
•akagana, B.
Tatao, g.
1980
tBVirona«ital B«s*uck
22:22-30











{lilt »»«) 	 — -
                                                                                                                                                                                      hO
                                                                                                                                                                                      o

-------
Bercnry
1««-9T-6
Bq
lt» 200.59,
              1 -38.87 C, BP 356.72 C,  TP  2110(E-3)  m Hg at 25 C, 100 BB Bg at 260 C
TISSUE
• 211
Bair
•212
Hair
• 213
Mart
»21«
Bcut
iiposun son


1
l

aninicii
BET BOD
US

n
l
1

» nsiis
or cisss
339

a) 10
W «
f
B1IGE
2-52 ug/«

a) < or « 1.1 ng/g (net
t)
) < or • O.B1 ug/j (ret
«t)
lot applicable
Bill | CBIE11L rtTOlBAflOI 1 8EFEHEBCZ
1 1
1 1
1 1
lot gi»«n | f«ir adjaceat to scalp. Estimated I Phelps. B.v.
I frea graph | Clarkson, T.».
1 | Kersaav, T.O.
| Ontario iBdiaas »ho ate coBtaBlaated j »h«atl«y, B.
I fi*h. I 1980
j I archives of
| HOOD: Bill; BEBCOBI; IET1LS; CM1D1; 1 EBTironBental Health
1 EOPDIITIOB iiposms: risBis; DIETS i 35<3i :i»i-i«s
1 1
1 1
I 1 r«»l«» of mrld llteratare OB the 1 Jankiaa, 0.*.
I acewlatloa *nd blooanceatratloo of 1 1*79
| nlectail toilc trace aetals in h»av 1 EPl-60D/«-79-tHt9, la*
j hair aaft nails aid other unallaa I pp.
1 talr, far, aalls, elaws and boat*. I
j latalatea by geographic area, j
I objects, s age »0. 6 rr. Toalea, 1 Itehires of
I IHD ao« 37.4 fr. I FnTironeenttl Bealth
1 | 35(1) :36-M
1 TSICI SLisins: itrropsm; JIPII: I
1 HiBidiii: (PSEirrc: CIDBIOB: cosiic; 1
t CIBCSIO1; CCPPII; IBOf; BEtCDBT: |
1 IICITH; aieiisioB; BMeiizse; i
1 I OB ID lU 9: 1IHBOBT: SCIIOIOB; |
I ;n.snvi: Tiiifios: TIHDIHB: xnc: r
I eciD; BBOHIII: IITEI; noins: i
1 CIBIB101; CIBEBBltn0.5 ppe total Bg 1 Salth, J.C.
1 1 1981
1 Caaaiian ladlaa, northwest Ontario j Jonraal of laalytical
I 1 Toxloologr 5:90-9«
1 iisais: FOOD ooiriBiiinoi: i
I iiggsmii pouotioi: POPOIITIOJ i
1 IIPOSVI;: tnui «sis; DBBII 1B1»S; i
1 ntn poitniof; HSsaKT: BIBCDTI i
| CfCHIC CCSFC01B3: BE1IT; III1ZTS; I
I tifti: rticim: spini; cinoi: i
I ItTOPSIES |
(lltT PaGI)
                                                                                                                                                                                           ho
                                                                                                                                                                                           o
                                                                                                                                                                                           00

-------
lereory
7««-*7-«
It! 200.59. St -38.87 C. M 35C.72 C. n  2X10(1-3)  u tq at 25 C, 109 •• Hg at 2«0 C
1XSSH

1215
Kidney
















•21C
Kidney





















•217
Kidney











(218
Kidney










IPOS USE sans










































Ingestion
Inhalation











Ingestion











lliLTtlCil.
BETHOD
U

















11






















U











GC











IUBSIB
or CISES
a) 20
b) 3
















a) 8
b) 9
o »




















a) 5
b) 6
c) 2










1











IMGI

a) < or - £.6 «g/g («et
•t)
b) 0.98-3.6 ng/g (vet «t)















a) 0.05*-0.027 ng/g
b) 0.017-0.50 ng/g
cl 0.0*1-0.47 ng/g
let tit



















a) 5,500-21,000 ng/g
b) 79-8.000 ng/g
c> 30.1-364 ng/g
fresh »t









lot applicable











Bill

a) 2.0 » or - 2. a
ag/g (net «t)
b) 2.* » or - 1.3
eg/g (««t irt)














a) 0.091 ag/g
b) 0.10 »g/g
O 0.0*6 ag/g
Vet »t
Redlans


















a) 12,224 ng/g
b) 1,227 ng/g
c) 197. »5 ng/g
Fresh irt









1223. t ng/g fresh «t











emiii nrotBmoi

a) Bales
t) resales

Iron a groip of «1 intopsies.
forensic sedical examinations. Japan.
Rales, Man age «O.S yr. resales.
neaa age 37.4 yr.

1IICE ELEflMIS; ITOOPSIIS; MPtl;
itoaiina: iismc; CUBIUB; COBUT;
CMOBWB! CCPPIB; isoi; BIBCOBT;
•»iiria: iniBort: SCHOIOR;
SIIEII1S-, TITHini; TISIDH3B; ZI1C;
«OtD; BSOBI1I; LITIB: KIDI1TS;
C1BEBBBSJ CltEBBLlOB; BElBt; BOSCIBS;
EllCmtaS; S5IIM; IOIGS: lOITa;
BJTIIS; COR11S1TITZ HiLDlTIOHS; SIX;
ICIEISIC BEBICIIZ
a) Control*
1) lorker groop I
c) lorker grogp II

Kceased refinery and snwlter
letters, ages 55-76 yr, exposed to
keaiy totals 1-3 decades, tine
tttveen retirement and death 0-1.5 yr
it group I anil 2-19 yr, groop II.
Controls, ages *3-72 yr. »bo lived SO
III fron the factory. Sweden.
sut ii: cioitras; EIDIETS; imi;
HUBS; COBPJEITITE ETliniTIOKS;
IVCQSTRIll BIGI2BE: HEaSOBBBEHT
HITEQDS; MTIBOtt; USSBIC; CaOSMB;
CISPJB; CIBOBIItl; COBUT; COPPEB:
eOlD; IIOI; URBalDR: LEaD;
(llOlKESf; BIBCOIT; ROITBDENH:
FBOSPHOSOS; BDBIDIOR; SCIIDIOH:
fllElIO!); SIITEB; Til; TOIGSIEI;
zi«c: Bttna laiuis: noosmii
FURS; SBEITE8S; TELLOaiDB
..
a) Occnpationally exposed
c) la exposed area
c) Controls

Tgqoslatians, ages 1«-7S yr.
Intopsies.
IIDW3TR11I POLIOTIOI; OCCtJPITIOJII.
Hl^lltDS; POPQ11TXOR EIPOSORS;
SUBGEHT; BtXCDBI: "IEBCUBT OKOiHIC
CCiPOOBDS; TdGOSLIITII; iBTOPSIBS;
HOOD; B«»II; !tID»BIS; 1ITE5; IOHGS;
BDSCLES: SPL1EH; TBI8OID G1IIDS

Intopsy, regular consnner of fish
containing >0.5 ppn total flg

Canadian Indian, northvest Ontario

FISHES; FOOD COffitlBIUTIOi:
naosTBiu FciioTioi: POPOIJTIOJ
II?OSOBY: BOBII IREIS; IBBJH IHJIS;
nits potiinio*: BESOT ai; aEscnn
Cf5»lIC COBTCmiDS; BE1BT; XIDRETS;
tlTEB; P11CIR1; SPLI'S; CH1D1;
1ITOPSIES
itnincs

Inkaia, B.
SaTtki-lannoto, B.
Isano, K.
Teral, B.
1980
Archives of
Environmental Health
35(H:36-«»










Brane, D.
•ordberq, G.
•ester, P.O.
1980
Science of the Total
InrironMat 16:13-35

















Kosta. 1.
Zelenko, T.
BaTnik, T.
levstek, B.

Byrne, l.B.
Coaparative Stadies. of
Food and Earlron.ental
Contanination.
Proceeiings of a
Syaposina held in
Otanieai, Finland,
ingvst 27-31, 1973
Cappon, C.J.
5.1th, J.c.
1981
Journal of Analytical
Toxicology 5:90-98







(Hit PJSI) 	
                                                                                                                                                                                             K)
                                                                                                                                                                                             O

-------
ttreaty
1M 200.59, B* -3«.«7 C, B* 356.72 C,  va  2HO(E-3)  aa Bg at 25 C, 10O aa 89 at 2«0 C
                                                                                       CCOItllOBD)
II9SBI

«1»
(idaer


















«220
liver


















(221
Ilrer






















lirOSVM BOOT!

laaaUttoa































































aiunicu
BCTBOD




















U















1
I
1

U























1TJHBM
OF CaSBS
1



















•1 5
M 7












1
1
i
1


a» 8
b) 9
ct *





















niai

lot applicable



















•) < or - 1.7 »9/9 (Mt
vt)
b) < or - 6.0 vg/g (net
•t)














- - i
t
») O.Oie-o.l* no/?
b) 0.016-0.10 «9/a
c) 0.01S-0.13 09/9
let at




















nil | GBIZIll IirolBlTIOB
1
12.2 09/9 | latopsy, 7 ao old girl exposed to
I vapor, 91.
I
1 Tever, vosltlag, pallor and dyspnea
1 fellowd Mvaa dare later by apiea.
1 cilateral eaeasothorax. severe
1 ecidocis, coaa, aellare, aad death.
1
1 fartlal atalectaais «lta svelllag.
1 fecal atypical ayaerplasia. aad
| deagueatiOD of cell* of alveoli.
| alveolar deets. aid bnwchiolei*
| Byallae seatraaes. aad imtra-alvcola
f ctaaoas la tldaey*, Jiffase fatty
1 caaage* la liver.
1
I gissiCBtsms; IUTOMIES; CISB
| tlSTOKBS; ItTlaTS; Wilt WlSOinC;
t iia»t KiBiirs: IITBII loves;
| BJtCOlI; BHllS: IBBEL1TIOB
a) 0.60 » or - 0.70 1 «» Bales
39/9 (vet vt) ( t) Tevales
b) 2.3 * or - 2. • )
ao/o. (vet «t| | froa a groan of 61 aotopaiea.
| foreasic cedlcal eiaalnatioas, Japaa
t Bale*, aaaa ae* «». 6 yr. Veaales,
t aeaa age 37.* yr.
| TB1CI nSBBBTS; UKOPSIBS; JUII:
1 tiraim: ustncs ctosion: COBUT;
I cnoiiai; copRB; isoi; aBBcnxy;
j UOIUB; BlGBESIBBi IIIGIIBSB:
1 usiDins; airiHOaT: sctanma;
1 siLmos: TiTinw: THUDIOS: tire;
1 eoiB; BJOBIII: urn; n»»iys;
I CMinvii; CIIBBZUVB: BBaBT; BOSCLZS;
| 'IICBI1S; SP1BZI; IOKS; lOBTai
| IRalS; COBFIBITITI BTUDlTIOaS; SKI;
| VOIIfSIC BFCICIM
1
|
a) 0.037 nj/9 | a) Coatrola
b) 0.03* 09/9 | b) Worker groap I
ct 0.037 eg/g I c) Vorter groap II
«et vt i
Sediaas | tteeased refiaery aad acelter
j vorkers, age* 55-76 yr, exposed to
I beavy aetala 1-3 decades. liae
I r«te*ea retireaeat and deatb 0-1.5 yr
1 Ja aroap I aad 2-19 yr, group II.
I ceatrola. ao.es 13-72 yr, »»o lived 50
1 ka froa the factory. Svedea.
1
1 sum: cturas; cirans; urn;
| 1D65; CORfaBtTlTZ ITIU17IOIS;
1 IltOSTtlll BTfilZIS; BSlSOnBZBT
I BTTBODS: miBon: usnic: caDRioa:
t cuwi; cnoanrii COBIIT; COFPEB;
| fiOID; IBOV; UtTBJIOS; IBaD;
1 •iieiiisi: incoBT; BOLTBDMOTI:
I iBospBoias; BIBIDIOH sciigitm;
I sitinra; sum: tii; Toissni;
1 me: IIIITB uiuos: novsTBiu
i titns; sniTns: -numis
i
IBFIBEBCE 	 1

Boatlabo, B.C.
Toapkias, a. I.
lovlaad, T.I.
Baasoa, B.B.
Jacksoe, 1.8.
1981
itericaa Joantal of
Diseases of Ckildrea
135ft] :<2-4«











y«xa>a, a.
Saiaki-Taanaoto, B.
aaaao. K.
Teral, i.
t»80
archives of
Bavironaeatal Bealtb
35fl|:3*-«a












raae, D.
ordberg, S.
ester, P.O.
ego
cieace of tie Total
aviroasent 1C 213-35


















                                                                                   (MIT t»SI)

-------
earcarr
7«3»-»7-«

Itl 200.5*..
              ' -3*. 17 C.  tt  356.72 C, TP 2110(1-3) SB  89 at 25 c, 100 aa Bg at 260 C
                                                                                        (COBTZinEB)
nasai

122]
liver










«223
liver








4224
liver


















•225
laa«

















EXKStBE BOntX

lagestioa
XabalatloB




















lakalatlo*.






































niimcii.
«WO»
n










ec





























„


















B08BEB
or cuss
a) 5
b) «
c| 3









t









1



















«) 3
b) 2

















I1KE

a] as.711 Bg/g
b) «1-1«» avg
!) Is.s— 48.B ag/g
fresh «t








Bot applicable









lot applicable



















a) 0.28-2.0 ni)/g (vet «t)
b) < or > 0.06 ag/g (wet
•t)
















BE1B

a) 250 ag/g
b) 99 ag/g
e) 34.5 ag/g
Presh vt








14 5. 7 ng/g fresh wt









5.1 ag/g



















*) 0.17 + or - 0.9B
ag/g (vet *t)
b) O.OJ * or - 0.04
ag/g tvet vt)















GSIIBU IimilTIOl

a) occapatlcaally exposed
i) IB expose! area
c) Costrols

latopslet. Taqoslaviaas. ages 1S-7S
7t.
IIOOSTtlll PCUirtXOB; OCCVMSIOIU
BataBDS; POPVLaTXOB EXfOSOvBj
snenr; ancmi; mem* oismc
CCBJOBI&S: TuaosiiTH: movsiES;
HOOD: BttiBt KiDnis; iifii; Lmes;
BQSCLBS; SPIEBI: TBTBOIO QlaVOS

litopsT. regalar ooasaaec of fish
eeatalatag >0.5 ppe total Bg
Caaadlaa ladlaa, aorthvest Ontario

iisns; n>oi coRuxuTioi;
IBDDnSIll JOL1DTIOI; POP011TIOB
IIPOSUH; tttBaL MlaSJ DBBIB UMS;
IKCT ponutioi: TBscosi; aiscoii
ciGinc coiMviDS: HWBT; KIDIIISI
lITIt; FLlCtni; SPIESI; CIIID1S
latopsf, 7 ac old glcl eipoaed to
vapor, la.

Kver, voaltlaq. pallor a ad dyspaea.
followed sevea dar« later bv apaea.
t {lateral pienaotboraz. severe
aeidosis, cosa. celxare, aid death.

Partial ateleetasls vita mil lag.
focal atypical kipatplasla. aad
desgnaaatlca of cells of alveoli.
alveolar dncta, aad ferotchioles.
Bfalia* Beatzaaes. aad latra-alveolar
aeaorrhages observed. Degeaeratlve
ciaages la kUaeTa, Uffnae fatty
ckaages ta liver.
MSSacmstns; inorsxES: cisz
BISTOSIE3; TirilTS; BSTtl POISOBIIS;
tllll; KXEltIS: 1ITEB: 1DB6S:
HlCmiT: BPI115; nBallTIOB
*) Bales
I) Tvsales

Iraa a groap of 61 aatopsles.
forensic aedlcal exaaiaatloaa. Japan.
Bales, aeaa age aO.« yr. reaales.
aeaa age 37.* rr.

TVICE I1EHIIS; iBTOPSIIS; J1P4I;
iioBiiiji; t«smc; CWSHJK; COBUT;
CBSCB1U1; COfPElj IMI: HBBCOBI:
ncran: iiisiEsniB: IMGUESE;
lIBIEItl; iniBOHI: aCMDIOB;
SltMUPI; TIIMigg; VIIIDIOB; ZX*C;
COLD; BIOBUI; inn: KISBBTS;
ciitaim; ciBEB'iitifl: IEIIT; nnsais;
IIICBMS: SPLXEI; lOKS; aOBTt;
VI1I1S: conaakTITE EfUDitloas; SEI:
fCIIBSIC RIDICXK
(IIXI PIG!)
IETEBBBCE

Kosta, 1.
Celeako, v.
Bavalk, T.
Levstsk. 1.
Seraelj. 1.
Byrne, I.I.
Cosparatlve S tidies of
Pood aad ZDVlronaeatal
Coataalaatloa.
proceed ings of a
Syaposiua held la
otanlssl, TlslaB.4.
avgist 27-31. 1973
Cappon. C.J.
Salta, J.C.
Joanal of laalvtical
Toxicology 5:50-98






•oatlako. B.E.
fOBpklas, l.L.
8o«lt«d, t.».
Baasoa. B.B.
Jacfcsoa. ».H.

laerlcaa Joaraal of
Diseases of Cbildrea
135(1) «a2-«*











Tokava, B.
Sazakl-Iasaaoto, B.
liaao, I.
Taral. B.
1*80
arealves of
Zavlroaseatal Eealtb
35(1)! 36-44













-------
tttevij
•s
itl 200.59. IP -38.87 C. BP 356.72 C,  vp  2110(1-3)  u Bg at 25 C, 100 •• Bg at 260 C
                                                                                       (C01TH1EO)
IISSOS
4226
lug
«227
Ian?
• 228
I«g
t
EXPOStJIE BOOT!

lagestioa
Inhalatioa
lakalatioa
I iiaiTTicii
IBTBOB

n

10HBKS
or cisss
a) 8
b) 9
C) •
«) 3
bj 5
1
1
1

B11GB
a) 0,0010-0.17 mg/g
b) 0.018-1.13 og/g
C) 0.012-0.097 »g/g
let lit
a) 127-1510 ng/g
1) 12-271 19/9
Trash vt
lot applicable
iiti | GIIZUL nroEaiTioi i miBBici
I 1
i i
I I
a| 0.00*0 «g/g I a) Coatrols | Prase, D.
b) 0.031 og/g I b) vorker groap I I loraberg. G.
cl 0..038 ng/g | c) Worker groap II | tester, P.O.
let *t I I 1980
SediaBB t tseaasea refiaery a ad saelter I Scieaee of tbe Total
| loiters. «q«» 55-76 TT. «rpo««a to I ZniroiMnt 16:13-35
| I««TT Mtals 1-3 decades. Time I
| tctveea Tetlreseat ad death 0-1.5 re 1
j it gtoip I aid 2-19 jt, gconp II. 1
I cmtrols, aaes 43-72 jc, vho llwd 50 I
1 ki froi the (aetoCT. Snedea. 1
I sncEi: cioitnsi XIOIETS; LITXI; i
1 IHIGS: coHPiiiTire BTILOITIOIS: i
I IIDDSTII1L BIGIEIK; niSOEIBZIT 1
| BIIBODS! IIIIHOIT; »5»IC: C1DB30B; |
1 CISDB: CMOBIDI; COBU.T; COPPBI; t
1 SOLE: IKOI: unuiiB: HID; i
1 iiismsE: BZtcnBi; HOIIBDBIOH: i
1 ftOSPHOIUS; TOBIDIHB: SC11DIDH; |
| 51LEIHTH: SIITJB; Til; TOI6STEI; I
I uic: BIHTI Hizuas; IIDHSTBIH i
| EI1RS; SBS1I1RS; TEUORIDR 1
1 1
1 1
a) 77t nfl/g 1 a) OccipatioMllr eipased 1 Kosta, 1.
b) 131 n 7 1C old girl exposed to 1 RootiBbo, H.E.
I 
                                                                                                                                                                                          N3

-------
Bercarr
It! 290.54,  IP -3I.IT C.  » 3SC.72 C, It 2110(1-3} an «g at 25 C. 100 an Bg *t 260 c
USSBB

1229
laacte

















4230












1231
tail















ET.KOTH HOOT!




















Xaotstlon
Inhalation












Ingest ion
Inhalation
Oeraal














1IUTTXCU.
BZTBOD
n


















n












Bl















IOTSIS
OF ClSIS
a) 6
1 »

















a> 3












2















E1WI

] < or • ».« »g/g (»«t
t|
b) lone aetoctftd'
















a) (.5-106 ng/g
b( 1. 9-2* H4/9
Fresh vt











a) lot giT«»
b) lot given
c) lot given
4,1 Hot ?U«t













BB1*1 | GHESIL IIFOBBUIOI
1
a) 0.77 * or - 1.8 1 •) tales
eg/9 (vat vt) | t) Fe aal«s
b) Kane detected |
j Iroa a groea of *1 autopsies.
| forensic aedical oxaniaatioas, Japan.
\ Bales* aeaa ao^a 40*6 vc» F«»a,V*s,
1 aeaa age 37.4 vr.
| TtlCl ILIB1B1S; JOTOPSIISJ JIP1I;
1 itunnm: tesEiic: CIDHIOB; COBILT:
| CESOBlai; COIFEB; ItOI; HSBCUBT;
| IIUIBB; IISBtSKIl: MIGUISC:
1 euBiDirn; iiiiutPir: SCIJDIDI;
I SIT. MTU": TIttBItrg; tilaOIUB; ZIIC:
I 6CID: BBOBI1I; 1IVIS; KIDHTSi
I CIBIBSTS; CIEEBEiina; BSUI; HHSCLSS;
1 PiicEiis; sritia; loBss; toni;
1 amis; COHfHtTITE l*llD«IOaS! SIIj
1 ICBItSIC BEDICIITE
1
a) «3.5 ng/g ( a) DecapaticnallT «iposefl
b| 1«.0 ag/g I t) In «zpos«a area
Fresh vt I
t latopsies, tagoslavia, ages K-75 yr.
|
t IKVSniU POIIBTtOI; OCCnTtnOML
1 BII1SDS; POPOtiTIOl HPOSHSS;
l smsEii; nrtcusT; IUCQBT assuic
1 COBPOIigS; USOSLITH; tUTCPSIES;
1 HOOD; B1IIB; KIDfEIS; IITEB; LOIGS;
1 stsciES; spirei; TIYBOID eims
l
1
l
l
a) «9S ppa | i) Case 1, fingernail
bl 313 ppa | t) Case 2, flag«rMll
c) 17.1 ppa 1 c) Case 1. teenail
4> «.S 5?» ( S> Cue 2, tcevall
1 leak levels
1
1 Dentists. *• nd so vr oil.
1
1 linger treaor, vlnal deterioration.
1 [oor aeaory, irritability, headaches.
1 nisele pains, aaocezia, veight loss.
1 lacoordlaaticn of llabs, nausea.
1 euphoria.
1
1 sconiiD; aiTii FOISCIIKG; BUS;
l unsi aiBCDEi; IIETIIS: ocetPiTiosiL
1 BiiuDS: stems; DMTISTI-T
AEFEBZICE

Tokau, B.
snnki-Tasvnoto, 9.
laano, K.
Terai, a.
1980
accVives oC
Zavlronneatal Eealth












Kosta, L.
Zeleako, T.

lerstek, B.
Darnel j, g.
Byrne, I.E.
197*
Coapacatlve s^vdlos of
Food aid Eavironneatal
Contaninatlon.
Proceedings of a
STapoaiae held in
Otanleai. Finland.
Kigast 27-31, 1973
Svnington. I.s.
Cross, J.D.
Dale. I.a.
lenihai. J.I.I.
H80
Journal of the Society
of Occupational
H«Ucine 30:37-3*










-------
BcrewY
Itt 200.54, tt -M.tT C. tt 3SC.12 C, » Jit 0(1- 3) aa Ig «t 25 C. 100 » 19 at 2«0 c
                                                                                     (COBTIBPED)
TISSVB
«232
tail
«233
•»il
•23*
Patcreas
sxtosviB ton



•IU.TTICU
nraoo

u
u
•rani
or cuss

a> 9
b) It
7
3
tlKC

•1 Mt aiT«»
b) lot «!T««
a) < or • C.«5 «9/j (Mt
«t)
b> < or - 0.81 09/9 (»et
•t)
BEM i GiBitit XBroiBiTicir i scnazBcs
i I
i i
I 1 r**tmt of meld llt«c«ttr« o* the 1 Jmklai, 1.1.
I accaialatloa aid biocoKftatratloa of I 1979
1 *«l*ct*4 toilc tr«c« a«t»la in bnaaa 1 lM-«00/»-7*-0»9. 18*
j kilt »4 mils »i oth*r aaaaallaa 1 pp.
1 aalr, (»c. Mil*, clan* aaft boots. I
1 I»fc»l«t»d by 7*«9Tltbf 20-60 TC alia I Uastlfaon, P.S.
1 | »«l»oo. 9.1.
l itnits: szi; mis; BITIEB ; iionmB; i Boor*, c.c.
l mnaiTi HSBixc: S»SWB; cmatOT: I 1979
1 citcim; ctsnw: CBIOHOB; ccaiu; i sd«»c« of the Total
1 CCPPEB: «»(invc SCUD; IBO«: HID; 1 Zarlroaiut 13:131-1*0
I S1GIESIU1: BIKAIESB: RSBCOBTi 1
I (ciTBDinB; nctn: rotission; i
| lOBItm: SIIBIIIH; SIIICOB; SILTSBi 1
i sorrow: STtcirrtrs: TIC Tinrrua; i
I tJUDIOB; MIC; IIBCO1IDB 1
1 1
1 1
a) 0. N * or - O.IT I <| »«Ie» ! Tak9», B.
•j/j (»«t «t) | 1) F«»*l*s 1 S»t»lcl-T««m»oto, g.
b) 0.27 » or - 0.«7 I 1 laaaa, K.
19/9 f**t *t) 1 ttoi * ?ro«p of SI avtapci**, 1 T*r*i, B.
1 farcaslc i«41c*l azaitntioie, Jip»». I 1980
1 Bales, Mas »9« IO.C yr. P«a»l«s. 1 Irchlies of
1 i«*» *9« 37.* TT. 1 EaTtcoaavatal 8*altb
1 1 35{1):3<-«
l Tiict nsiizns: tmorsits: JUIB: i
t iiBBina; iBsnic; cioatna: COBU.T; i
l ciioiUBB: ccmB: IBOB; BEBcrai: i
1 113t08t BIGBCSXIK: B1B61VESB; 1
i inttma: iniaon: SCIBHVB; i
l siisnos: tiUBioa: nitDiua; IIBC; l
1 COID: moBiii: insi: nvtzts: I
I ctiiBtoa; cnniuoB; mm-, suscies: i
1 flBCIMS; SFtSSBi LVKSi 1OIT1: 1
l 
-------
7«39-97-«
•«
It* 209.59,
               -38. 97 C, BP 356.72 C, TP  2110 [1-3)  u flg It 25 C, 100 M Hg «t 260 C
TISJBB

»23S
PitaitatT












• 2J«
Placenta







W3T
Stleea

















Spleen











•239
Spleen









SIPOSIJU tOIRE
























	 .


















Ingestlaa
IBkalatlOa






















ifiimcii
BTSBOH














9C








n


















»











sc










EOT in
OF CISIS
*
s
3-




















at 9
b| *

















•1 3
M 2











1










U*6I

19,000-C«.Oa4 a«/g
163-23,900 ng/g
6.V-63.6 »g/g
nab «t










2.0-20.7 ng/g fresh «t








at < or » 2,1 »g/g (met

>) < or • 1.S eg/g t*et
•t}















a} 23-188 Dg/g
b) 11.8-20 ag/g
Fxe*h Vt










' lot applicable










IE* i i esiEtu. urosiiTioB
1
•.6,000 ng/g 1
$.225.* mg/g 1
SBC'S •4/9 i Iv^oslwimSf &STt:
l Biiiis; cogpiMTifE ETiiaincvs: sir;
1 KBEISIC BtCICIBE
1
a) 79 ag/g 1 al Occvpetlaiallf -exposefl
b) IS. 9 ag/g i fe) In expoitd araa
Fresh vt |
1 latoislaa, TBgoilarla, ages H-7S TC.
1 I1DOSTTU11 PCLtVTICB: OCCOElIIOIll.
I BtllBOS; MPBHIIOI ZIFOSOBS:
1 SOtCZBT: BJSCCST; BBSCOET OBCUK
I CC1WTI1DS: IBSOSLITII; IJTCPSieS;
I noon: mil: Kisratss mis: LOTOS;
I HSCLESl SfLEEI: THTBOID GIHDS
1
1
t
1
80.* ag/g freu vt I latopiT, regalar oo*s»er of flak
I cc»t»lal»q »O.S fpm total Eg
1 Caaadtaa ladtaa, »ortk«est Oitarlo
1
I ftSBES; FOOD COMlHIBlttOI;
\ IIOQSTItlftI, fQtd>mTOl* BQ¥1Ht>TIOV.
l IIPOSDRE: «OBII nits; TOSH isiisj
1 flTEB POttBTIOI: HEBCUSI: HMCtlDI
l cismc canpomros: BBIBT; KIDIEIS:
1 II1R; PtlcBBIi; sPlEEr; CUUDI:
i
lEnmcz

KOBta, I.
Zeleato, T.
BtTBiX, T.
leiatek, B.
Deraelj, B.
BTEB«, I. S.
1»7<
CoapacatlTe studies of
rood aad EiTlronaeatal
coataalaatloa.
Proceedings of a
Syapotiu held la
Ctaaleal, riolaml.
aagvst 27-31, 1973
Cappoa, c.j.
Salth, a. C.
1901
Joacnal of Inalrtlcal
ToxlcologT S:*O-38



...
Tukava, S.
Saickl-Iasaaoto, a.
laaao, K.
Teral, B.
1980
acclilTes of
EaTlroamntal Health
39 (1) • 3i— %l











Zeleako, T.
Bavaik, T.
levatek, B.
BrcaJj''!.^
1974
Coapar attire studies of
food aad Eaviroaaeatal
coataalnatlon.
Procaedlaga of a
Srapasioaj held in
ctaaleal. Finland,
iarjiut 27-31, 1973
Cappoa, C.J.
Smith, J.c.
Joacnal of Analytical
Taxlcologr 5:90-98








-------
tticw
7M9-97-4
Bg
Its 200.5$. I? -38.87 C, BP 3S6.72 C. It 2I10(B-3) u Bg at 25 C. 100 •• Eg at 260 C
                                                                                     (COIII*BED)
iissat
»2»0
Thyroid
gland
• 211
Dtiae
«2»2
Orine
«2*3
Ori«*
iirososi BOUT
Inhalation
Ingest ion
Ingest ion
ejection

1 t 1H1TTICJU.
BETBOD
u

us
us
BHRBEB
OF CIStS
a) 5
b| 6
0 3
d| 6
1
6
6
<
1IIGI
a) 21,300- HI, 000 ng/g
b) 69-26,500 agyg
C) 2.5- 15 ng/j
4) 7.1-507 ng/g
msn vt
•} lot applicable
n> lot applicable
-
) lot applicable
) lot applicable
) 23-66 ng/sl
5. 80-25. OD ag/2» hr
<1. 0-2.3* «g/2« br
Bin i GEBIM.I nroiauioB i sntsstcs
1 i
i i
l l
a) 51,222 ng/g I a) Occnpatiosally exposed I Xosta, 1.
b) »8»2.5 ng/g 1 t) In etposel area I Zelento, T.
c) 10.2 ng/g I c) controls I Ravnilc, T.
d) 11* ng/g ) d) sorfieal patients, one of *ban | terstek, B.
rresl «t 1 Dotted »Jth Eg and kai kigbest tissue I Decnelj. 1.
I l«nl. | Byrne, i.1.
1 1 t»7»
( I agoslariaas, ages H-75 yr» | Conpacative studies of
1 1 Contamination.
( IIB5STSIII POUBHC1; OCCIMTIOUI, I Proceedings of a
| BJZ1SDS; POFOUTIOI E1POSD8I; | Synpoalnn held in
1 soieiBT; BiEcoBT: siECtrar OEGHIC i otanieni. riniand,
| COSEOB»OS; roOOSIlTIl; 1BTOPSIJS: | Jognst 27-31, 1973
I EIOOD; BB»I»: KIIRTS; LJTSB: LOTOS; |
| 80SC1ES; SPHEI; THTBOID CtalDS 1
1 1
a) 90* ag/1 I a] It adeission 1 SeUel, J.
b) 1330 ag/1 I B| Hospital d»T 2 1 1980
| rose, 9S9 sg sercncie chloride 1 Pediatrics
| I 66(1)! 132-1 3«
] «.S TT old Bciicai-tMrican. I
1 1
I Tesiting, abdoiinal pain, diarrhea. 1
1 1
| Cloodr stools, protein aria I
1 1
| CIIIE; 1XBCOBT: BCTltS; CBILCSI1; |
| Hill POISOIIIS: CISE HISTOBHS |
1 1
1 1
a) 63 ng/il 1 *l Ifter 0.6 il/kg ga»aglobulii, f I Rethesoa. D.s.
b) 138 ng/nl I patient as In a) I clarkson. T.s.
c) lot given | t) Ifter 2 on/day I>-penicilla»ine, 1 | eelfand, E.I.
| patient, peak at 5 dars I 1980
| c) S patient* I Jon nil of Pediatrics
| a) end b) estiuted free grain 1 97(1) 1 153-155
1 29 TT old reoeiTing gaunglotalin, I
I contaiilnff 0.01V nertbiolnte (50.3 eg I
1 Ig/nl| . leceired »a-so sg Sg/rr. 1
I ether patients receiTiig 0.« il/tg 1
I <*err 2-3 ek. DO Sg sensitivity. 1
1 lint, scaling, pnritic palu and 1
1 soles, flnstcd cheeks, piotophotta, I
1 Irritability, treeoi. nltered I
I sensation in fingertips, sieved nerve I
j confection Telocity. |
l BticDiT: BRits: BLOOD: miE: ssin \
( EOISOIlfG: DISE1SES; DEUS 1BB1PT I
1 1
1 1
13.65 >g/2« hr I a) taw»aki disease patient* 1 orlovski, J.p.
lot given 1 t) Controls I fiercer, B.D.
| ) 1980
I 5- 11 yr oldi, vitb. (avasak.1 disea.se, 1 Pediatrics
I and controls. I 6«(«| :«33-636
1 1
I Terer, con1«Bctl*ttln, pharyngitis, 1
1 trTtnenn, trescal enntnen, cerrlcal 1
| idenopitky. 1
1 1
1 iiKgiT: inns; ntu. poisoius; i
| CHID1CT: OBHI; OISEISE3; CIS I I
| fISTOBISS t
1 1
                                                                                   inn

-------
Cercarr
7»39-«7-S

»t¥ 200.59, BP -38.87 C, BP 356.72 C, TP 2X10 (E-3)  am Hg at 25 C, 100 aa Hg at 260 C
                                                                                     (COiniHED)
HSSM
Urine
»2«5
Urine
Urine
IPOStJBE BODTE


Inhalation
aiunicu
mioo
us

us
•BIBE1
OF C1SSS
6
«) 70
b) «0

1 1101
a) 0-15 eoyl
tt 16-30 oj/I
c) 31-«5 «g/l
dj »6-60 ng/1
«1 > or * 61 a«./l
a) 0«OOV-0.«565 no/hr
b) 0.007-0.185 ng/hr
a) 0.007-0.614 vg/hr
b) 0.005-1.«01 ng/fcr
c) O.OOt-0.565 egAr
Bill | GEIEBH IlFOBBaTIOI
1
1
a) lot given I a] 3 patients
b) lot given I t) » patients
el lot gives | c) 7 patients
t) lot given I it 9 patients
e) lot given I •) 3 patients
| Bg dosage of «-73» ng (nean 1S7 >g1
( G). ovec 6 ao-17 vr (nean 6.5 vr) .
| *-C7 TT olds «ith
| 8IBCTBT; HFTILS: US III; DISEASES;
| CIKOTBIHP1
a) 0.076 » or - 0.012 I *) Controls
rea
b) 0.110 * or - 0.020 |
ag/hr 1 lonea. aesn age (2.3 Tr. fron
(S.E.) | Cd-eollated area (Liege), and
I controls, nean age 01.1 vr. fron
I Charlecoi, Beloiaa.
1
| BIOOD: BLOOD PLaSIt; Q1IIE: C4BBIOB;
I mo; asecust; tiic: BEIILS: BIIGIOB;
t is!-. popTamoi Exrosvis: IIDHSTBXU
| tCLLDIIOl: SBIITEBS; XIOIET KStlSSS
t
a) 0.065 ag/hr | a) Besilents of Liege (cost pollute*
b) 0.057 ag/hr 1 area)
c) 0. OM ag/hr I t) Besidents of Brassels (less
Seonetclc | icllvted axea)
1 c) tesideits of Charteroi (control
1 «•«)
I leans and ctmlative freqaemcr
1 distribaticns not neck different
I tetveen the three groups
1 Bsaltbr sablecta >60 ji old.
I iesl4eat> of the sane areas 25 vr,
I Hlgina
| EIIGTUB; ICBLTS; aSE; BLOOD PllSHi:
1 DBiit; c» cnioB: LE»D: BIBCOII:
1 IITM.S: me; IIDHSTBIU EBISSIOIS:
| tlDHSTBIll PCLLOTIOI; POPOUTIOB
1 IIPOSmtE; IBBtl 45BIS
SEFEBEICE
RaeaCT, H.B.
Carter, 5-F.
Teaian. ».B.
Thompson, B.a.
1979
British dedical Journal
lanervs, R.
Boels, B.
Bernard, i.
Bucket, J.P.
1980
International Archives
of Occepationa 1 and
Environmental Health
«5;271-27«
Boels, B.l.
Laaverys, I.E.
Backet. J-P
Bernard, ».
1981
Eavironnental Besearcli
2»s117-130
  Bercnrrtl*), Mtkrl-. ion (8 CI)
  •erc«rni»), »etnil- J9 CI)
  22967-92-6
  C-B3-Bg
  II 215.63
IIS5BB
•2*7
Blood


EltOSDBE EOHTE
Inhalation
-

111LIIICU.
BETHOD
U
oc


iraBza
OF USES
11. 17
controls


EIBGE
a) 67-518 ng/g
b) 100-15* tig/g
c) i.5-69.5 ng/g
d) 1.9-13.7 ng/j
BIT »t

(HIT
REal
a) 227 no/g
b) 129 ng/g
el 27.0 ng/j
d( 5.7 na/j
Dry »t

P1GB)
Gllntl IIFOBI1TIOI
a) Total Mrc«cy, dantista
t) Total aercvrr, non-exposed
ccntrols
c) dethrlnrcnrv, dentists
6) BetkTla«rc«rT, aon-erposed
ccntrols
Significant difference at P < 0.095
level.
viitto KIIGDOB: IOOITSI BIOOB;
CtHTISTBT: tEBCOSI; REKCOBT OSGIHIC
COBPOHIBS: Eioiccginunoi:
CCCOPMIOflt B1TISDS

BEFEHERCE
Cross, J*D.
Dale, I.I.
eoolvard, L.
lenlhan, J.a.i.
Smith. B.
1978
lancet 2(80811:312-313



-------
larcarr(1»>. Mtkrl-. ioa 18 ci)
aerCeTTd*!. a»tkyl- f9 CI)
SJ96T-92-6
C-B3-Bg
II 215. S3
nssa
«2M
(rail
424*
Brain
«250
laic
4251
••art
«2S2
Ildaey
ZIKSDBB MOT
laoastlon
lakaUtioa
Ingest Ion
Ingaation
Inhalation
gestioa
estion
•latin
1I11RXC11
8 FT BOD
n
sc
u
sc
t
IDS EH
or cis:
7
9
T


Ufa
2-26 ns/» freak it
17.9-1t«.0 ng/g rresk vt
270-1030 »g/g freak «t
ot applicable
26 ag/g freak «t
IEII i eniiii iiFomtioB i IERIIICB
i i
I i
9 ng/g fcesk «t 1 Ceeapatianally expoaed to inorganic t Kosta, I.
1 Eg ot living In exposed area t Zcleako, T.
I f Earaik. T.
t Ittopsles. Yugoslavian*, ages 19-75 I levstek. R.
1 ji | Deraelj. R.
1 | Eyrae. i.1.
I IID1ISTBI11 mtVTIOB; OCCDPIHOIU | 19?a
1 BltUDS; POPOtHIOf ZH050II; 1 coapacatlm stndi«a of
I ST18SEST: incoiT; HRCTBI C1G1IIC | Food and BavltoiMatal
1 CCIKrans; TOEOSUTI1; tDTOPSIIS; | Cootaalaatiaa.
I EIOOD; BB1II: 1CIDIBTS; LITIB; LtOMS: I Proceeiiings of a
| IOSCIXS; snm; TBTBOIO GIMPS | Syiposim k«U 1«
1 I otaniaal, Finland,
1 1 lagist 27-31, HT3
1 1
1 1
72.0 mg/g frask wt I tatopsias, c«gil«c eaBstmrs of fia-h I Cappon, C.J.
I ceataiaiaq >C.5 tpa total Bg 1 Saltk, J.c.
i . i net
t Canadian Indiana, aortkmst Ontario | Journal of Analytical
1 1 Toilcologj 5:99-98
f fisus; FOOD cotTiBinnoi: t
I lisreniit poiiinioi: POPDHTIOI i
| (IPOSm: 10 ML 1EEIS; USBll UllSi |
1 SITES poitmoi: BSKUJI: BIBCOBT t
I ciEiiic coRpcmDS: IEMT; IIBKIIS: i
1 IITIB; naCZBU; SPLBII; CUIDI; 1
1 10TOPSIBS 1
1 1
1 1
538 ng/g frank «t I Gccipatloinllr eipooea to Incrginic 1 Kosta, L.
I Bg oc living in erpoa«d area 1 Zelenko, r.
1 1 *a»ik, T.
1 litopsles, Tagoslariana, >g«a 19-75 I lerstek, 1.
1 Tr. 1 Berielj, I.
1 F Byrne, I.E.
1 HBDSTBIH EdLnHOI; OCCaPITIOlU F 197*
I imiDS; POPOllTIOB RKSOBB; 1 coaparstiw stadias of
1 SUBCXBT: HBBCOBI: BBBCOBT OBUBtC 1 rood and ZBTiconaantal
1 cetpcuiDS; lososiiTH: IUTOPSIES: i coataalnation.
I ciooo; ism; riciiTs; LITSB; IOTGS: i Pcocwsatags of a
1 BIfCIBS: SP1ZEI; THTBOIB 6IIIOS 1 Sraposiaa held in
1 1 otulani, Finland,
1 1 lagiat 27-31. 1973
« •
1 1
7.6 n«/g freak at 1 utopsy, ragalar conaaier of tlA ^ cappoa. C.J.
1 containing >0. 5 ppa total Hg | Snith, J.c.
1 1 1981
I Ciaidlu ndiin, nortinest Ontario 1 Journal of analytical
1 1 Toxicology 5:90-9*
I TISHIS: FOOD COITHIUTIOI; |
I utosTBiai. tavmot; POPTOIIIOI i
I fieosmx; BUIIL HBIS; UEBII IBBIS; i
i iiTm poLKnioi; BiROJsi; SIBCIBT i
| C5S11IC COIECOnS; BI1BT; KIEPBTS; 1
t 1ITCB: MICEBTl; SPLHI; C1I1D1: I
I inOFSIIS 1
1 1
1 1
ng/g freak at 1 Cccapatloaally expoaei to inorganic 1 Koata, L.
j Hg or liTinq la axpoaed area 1 Zeleako, T.
I t Barnik. T.
1 latopaien, Tigoalaiiaas, ages 19-75 I leratak, R.
1 It 1 DcrielJ, 1.
1 1 Brno. l.l.
I XIBOStBtll POIlUTIOl; OCCBtiTTOnU. | 197«
| BltHIS; POPOLITI01 KPJSini!; 1 Comparative stadias of
I S08SCTI; moral: IBBCVBT OBGHIC 1 Food and Environmental
1 ccipoaiDS; TIOOSUTII; IOTOISIBS: i contiaiaatlon.
I I1QOO: BtUI: KIBRTS; tITIB: 1OTGS; | proceedings of a
| IDStttS; SPttM: TBT80ID GL1B9S 1 Syaposiaa kali ia
I I Otaaleai, FinlaiS,
| 1 lagut 27-31. 1973
1 1
                                                                                                                                                                                     00
                                                                                  tmtn fast)

-------
i«rcacT<1»l, Mtlrl-* too It ci)
«erc«TT(t»|, awtkyl- f9 CI)
S!«67-92-«
C-B3-B.J
M S1S.S3
1IS30I

•253
Eidney









425*
Liver












•255
Liver










•25«
Ilacenta










•257
Spleen










inosm son!

Tngeatioa









laoaatlon
laaalaUm












Invention























Ingeatioi











llaUTICal
BET BOD
8C









n












ac











oc











oc











HJB8SS
OF C1SIS
1









7












1











3











1











MKI

•at applicable









10-28 ng/g freak «t












lot applicable











15.6—28.0 ng/g fresk vt











lot applicable











mi

78.1 mg/g freaa it









18 »g/g frank vt












95.5 mg/g fr«sk vt











22.3 mg/g freah vt











IOC. 5 mg/g freak vt











eilEIiL IIFOtRlIIOI

la-topsy, regalar canatier of flak
coatalalaq >O.S cpn total Bg

Canadian Indiana, nortkmat Ontario
MS BBS; FOOD CORUIUTIOI;
iiBvsrtitt vountioi; rornLanoi
MPOSUt!: BOBIL atlas; tJBBll »E1S;
IITEI potumot; mean; BBICOBT
CEGMIC COB»Onos; BMBT; KIC1BIS;
IITCT; TLUXRa: SH.E1": CHUIl;
lOTOFSISS
Cccnpatlonally expoaad to inorqanic
tq or llTi««j In exposed ar«a

latopsles, TaooBlavinns, aoea 19-75
Tt

HDUSTBUt fCllDTIOl! OCCVFHIOIU
HIlllOS; POfOItTIOI 0FOSDBI;
SOBSEBT; BEBCVBI; 1EBCOEI 0161VIC
CCtPOTIBS; TOGOStlTIl; ITTOPSKS:
HOOD: saiti: EIBIBTS: LITEB; inss;
"BECLIS; SPLEER; THIBOtt SHIDS


Ktopsy, raqilar cognaec of flsk
caitalninq >O.S tpn total tg

Canadian Indian, northvent Ontario

fl!B»S: FOOD conuinnoB:
iiDOSTiiai FcunnoB: POPOHTIOI
MPO50BB; KOIU, US1S: IBB 11 atElS;
IIIH paiivrioi; niaisT: SCTCOII
tsaiiic coBFcnos; HEIST: Kmsis:
ITTEl; ?L1CIR1: SP1EM: CII1DI;
1BTOPSIE3
fletkyl predaalnnnt focn (56.9M in
afaciaens

lealdeats of hlgkly IndutrlallTed
ax«a
IISIES; FOOD COITl»I»TIOl;
IIDOSTIIll FCLLVnOI; POFOL1TIOI
tlPOSBBE: tdi»L 1BE1S: 08B1B IB 'IS;
imn pounioi; nEBCOBi: BSBCuirr
CSSIIIC COBPCBIDS; BB1BT; KIKETS;
IITER; FUCIIM; SPLIEI; CU1D1;
1BTOI3I1S
lotoptf. reanlar coaannar of fiat
eeatainlng >O.S cpa total tg

Caaadlan Indians, nortkveat Ontario

IISBBS; FOCI CORHIMTIOI:
IIDOSTBI1I FOLLOTtOB; POPBI.JII01
Eiioson: BOBIL »EIS: OIBII tsiis;
IITEI POtllJTIOl: SEBCOSt: HEBcaBT
CtSlIIC CO8FCOTOS; 1X1R; KIDIITS;
IJTEPl mctRl: SFIZEB: C1UDI:
10TCISIES
BEFEEiBCE

Cappon, C.J.
snitk. J.c.
1981
Joaraal of analytical
lox oology -.90-98






Koata, I_
taTnlk.*T.
tCTBtex, H.
Dernel^. B.
Byrna, 1.1.
197 •
Coaparatln 3 1 alias of
Food and Environaental
Contaa {nation.
Proceed Ings of a
Synposlaa held in
Otanleai, Finland,
lagwt 27-31. 1973
Cappoi, C.J.
Saitk, J.c.
1981
Journal of analytical
Toxicology 5:90-98







Cappoa, C.J.
Saitk. J.C.
1981
Joaraal of analytical
Toxicology 5:90-98







Cappon, C.J.
Snitk, J.C.
1981
Joaraal of analytical
Toxicology 5:90-98







                                                                                                                                                                                         \O

-------
              £ CD
  Benzene, 1,3.5-triaethyl- (» CT)

  C1-H12
  •1 120.2. m -»».8 C. BP 1««.T C. TP 10 •• 89 at «7.« C
1ISS0B
(258
Breatk










«2S9
Breatk











EMOSOSB ROOT]
























1U1ITICU
BETBOD
8C/BS











GC-BS











BOBBER
OF CASES
8











54 (317
sa«pl«3)











I1IGE
lot detect«d-0.81 a«/hr











Mot 9lT«a











BE1I
0.12 ngyhr











O.S*2 ng/1
Gcowtcic










1
6»»1I IK01BITIOI
Ccipoaid related to >orial
Ktabollsi. lo otk«r tetalli qlrea
Cryogenic »»ipllttq technlqa..

8«althy aili tar T and ciTillaa
•iploreea, o.s. air Force School of
lerospaee «edicia«. ag«s 23-«7 ji. 3
siokers.
EflXnsS; CBIOBIIUBI HTDSOC1BBOHSJ
cnottiiB oieinc coipomms:
CE1CROBNZIIIS; FIOOIIIE COBPOOIDS;
CBI1T8; HCCBOLS; IET15; IDBITS
taanr«a at 25 C a«d 7 SO IB Rg
32.CV occurrence
to««r and upper ox-SlgBa lliita
0.327 »Dd 2.16 aa/1

Realtky, 18-35 yr old, nonsBokiaq,
artaa blacks aid caacactans.
Ckicaga. n. Biqillr controlled
experimental conditions.
flint; itccNts; IIIIBOIS; IDUITS;
CBICBIUTfO BIDBOCtlBOIS: T011THE
CBGIITC COSfCOIDS; HE11TB B1Z1ROS;
IIBtHTIOB: IRaBOlISI: IET1EOLITES:
EC?OHTTO» JUOSOIE; 3SB»B IBEaS
BEfEBEBCI
ConUe, J.P.
Caip, B.J.
Mick, B.E.
197S
irefciwea of
EnTironaeotal Bealth
30 (2): 290-2*5





Krotasiuwki, B.K.
Braaeav. e.R.
O'Heill, B.J.
1»7»
Journal of analytical
Toxicolovr 3:225-23*







                                                                                                                                                                                           N)
                                                                                                                                                                                           M
                                                                                                                                                                                           O
Ictkam
7»-82-8
C-H*
BI 16.05, B? -182.6 C, BP -161.5 C, TP «00 » Sg at -168.8 C
IISSOB

•260
Breath



ElfOSDB! KODTI





1
1B1LTTIC1I
RETBOD
ec/«s




BOBBIB
or cisEs
43




SMGE

0-32 PPI




R»l

S.1 ppa



1
I
GCBIIll IIPOBBKIOI

Corrected for lerel in inkalefl air

Eealtky adults
SIBBEB; 1 DOITS; HE»SBBE9EII IETRODS;
IIIR1BOL
EEYEREVCE

Jansson, B.O.
larsson, B. T.
1»69
Joarnal of Laboratory
and Clinical Bet hods
7«(6):>61-966

-------
Betkan, dlcUoro-
75-09-2
C-BJ-C12
•1 »».»«, BP -95.1 C,  BP 39.75 C.  TP 3(0 «• Bq at 22 C
TISSUE
«2C1
Breath










RPOSOtl SOOTE












ivaiRicii
BBTHOD
SC/HS











BOnBES
or cisss
8











MKC
lot tetected-3*0.0 og/»r











BM.B
55.0 ag/kr











SEBtML IlTOIBmOl
IrplOYM>> 0.3. iir POTOB School of
Icrospac* B«aiciae, a««s 23-»7 jr. 3
xaokaxs.
intnR; cBioiniTit nnocuiBOis:
cnoim OBEIKC COBPOOWS;
CBiowjEEiitiis: nnoBin coiMons;
iiena: ncflfiois; THIS; irons
XXriBBlCE
CODkl«, J.P.
Caapv B. 3.
Mick. 3.1.
iris
lrckiT«s of
EMironB»nt»l Health
30 (U -.290-295





         4icUoro«itlvoro-
TS-71-S
C-C12-P2 .
B<  120.92, BP -15B C. SP -29 C, TF S at* at t6.1 C
TISSJS
«262

I2C3
tile

•26»
Blood

• 265
Hood

MPOSBR BOOH |
1
Inhalation

Inhalation

Inhalation

inhalation

amiTIClt
BETBOD
ac

oc

BC

taiioaetcy

BtriBZI
OP CISSS
1

1

t

1

1HGB
lot applicable

Bot applicable

lot applicable

0.5-0 ng/al
(«BW
sail
13 »g/g vet «t

13 ng/g «et *t
_
1.2 og/g vet «t

lot applicable
PIGB)
Gill HI IBrOlBinOl
Ceeatae. litopsy sanple. Death 1.S
kt after sniffing cooking spear.
Bale, age 13 jr. kt 62.5 in.
11BOPSIBS: IDTPOSB IISS01; BILB;
EtCOD; 9B1II; HEIST; IXDIBTS: LITIB;
miss; anscus; CHIOKHTEP
BTtBOClBSOIS; P1IOIIBB COBPOOBBS
latops*. leatk 1.5 fcr after sniffing
cooking spray.
Bale, age 13 yr, kt 62.5 In.
itrtopsiES; itiposs tissBi; BUS:
EIOCD; BB1IB; B!»BT; KIDIITS: LITEB;
lUfCS; in SC1K: CBLOBIBaTBD
ItBSOCHSOIS; PtOOIIBI COBPOOTDS
Beart blood, lutops) sanple. Beath
1.! fcr after, cooking spray.
Bale, age 13 yr. kt (2.5 In.
i BIOPSIES; mpos: nssoE; BUB;
E100I; BttlB; BXUT; KID IBIS; 1ITEB:
mass; aoscLis; CBLOBIHTBD
ETDBOC11BCIS; TIDOBIIS COItOOIDS
It ani 5* ain after »S.» ag/aln,
16,75 ein. Initial neastirenent, .05
og/al at 0 tine. Bstlaated froa
graph.
HOOD; PLBCBIIE COBfOIIIOS; it BITS;
BiismaBn BITBODS
i


Staadefer, J.c.
1975
Journal of Porensic
Sciences 20(3) :S*8-551

Staadefer, J.C.
1975
Journal of Forensic
Sciences 20 (3) : 5*8-551

Staadefer, J.c.
1975
Journal of Forensic
Sciences 20 (3) :S»8-551

idle, J.
Blake, D.A.
mrgnar. C. B.
1975
Journal of Clinical
Pkaraacologr 15:760-770

                                                                                                                                                                                         N>
                                                                                                                                                                                         K)

-------
gathane, Aicaloroaiflaoro-
75-71-t
C-C12-M
•I 120.92, Ii -15S C, BP -2* C. f» 5 ata at 1C. 1 C
                                                                                     (COITIIOED)
tissos
•2CC
Braia
«267
Boart
«26«
Eiaaey
•269
Lime
«270
laao
»271
Basel*
EIPOSBIS BOB
inkalation
Isaalatioa
Inhalation
Inhalation
ahalation
halation
aULRICaL
RBTHOD
ec
sc
ec
ec
ec

EBB BBS
or cisES
1
1
1
1


BaiGE
lot applicable
lot applicable
lot applicable
lot applicable
at applicable
ot applicable
BE»B i 6BMUL iBFOBRinoi i BBFBBBBCB
i i
3.5 ag/g vet vt | latopsy. Death 1.5 kc after saiffiag I Staaoafer. J.C.
1 eeeklaq spray. | 1*75
1 - | Joaraal of Forensic
1 Bale, age 13 yr. kt 62.5 la. I Sciences 20 (3) sSa.8-551
1 1
| IHTOPSIES; 1CIPOSE TISSUE; BUZ; |
1 HOOD; BSIIl; BEaBT; KIDISTS; LITBB: |
1 igies: insciis: cnoiiuTsu i
| BTDBOCI8BOIS; TIOOBIK CORtOOIDS I
1 1
1 1
1(0 ag/a rat ot I Mtop«T. Death 1.S he after sa iff ing I Staadefer, J.C.
1 cockiiq spray. I 1975
1 1 Jouraal of Foreasic
1 Bale, age 13 yr. at «2.5 ia. I Scieaces 20 J3) :5«8-551 •
1 1
1 IOTOTSIS5: IBIPOSE TISSOI; BUB; I
1 tXOOD; gsillj BHST; KI01ETS; 1ITSS; |
1 miss; nosciis: CILOSIHTBD i
1 iToiocmcis; rinosui COBPOOWDS i
i i
i i
S.« 09/9 vet «t I latopsy. . Death 1.5 hr after sniffing | Staatefer, J.C.
1 cookli
-------
 Mtkeie,  ilcHoiotlmaro-
c-s-cu-r
II 103, »P -US C.  It «.9 C.  TP 2 at!  «t  28. « C
1ISSOE
•272
inttk










EirosoiE BOVTE



-








1U1TTIC1L
BZT80D
OC/HS










-
•01MB
or cisss
i











MICE
Bot OeteCted-0.062 ng/kr











SB1I
0.025 aj/kr











GEIZUL moiBaTxoi
Previous exposare to coipoavd. Bo
cthar ietaili gt*«tt
Cryogenic xanpling tecknigee.

ttaltkr illitMT ni clilliai
aneloyees, O.S. lir roree School of
aerospace Bedicine. ages 23-47 re. 3
(Mints.
««ii!3: cBioniaiBD nmociBBOBS;
cnomi oBCinc COBPOOBBS;
CBlCBOBntZBK; nOOIIBE COBMOBDS;
fBUTB; 11CCBOIS: THIS; 1 DOLTS
BZiniBCI
COBlEle. J.P.
Cup, E.O.
»«lck, B.Z.
1975
»rchl>*» of
EBTiroiMita.1 B«alth
3U(2):290-295





B«tb*M, dicHotomltio-
7119-89-3
C-B-C12-B-02
B1 129.93, BP 107 C
tissn

•273
Btutk












BIIOSIIBE Ksm















llltTTICtl |
BBTBCD |
1

SC-B3













IBS BIS |
01 cists i

» <3»7
•upl«s)











-
B1KI |

Bot ?lY«a













BB1B |
1
1
I
6».1 ug/l
Saoietric











_
CtllllL 1BPOBHTIOB

I«»mc*d at 25 C «»a 7CO mm eg
2*.St occncc«iic*
Io«• Bg. -23.0 C at 100 ma Bg. -32.3 C at SO ai Bg.  -39.0 C  at «0  n  Bg. -19.7 C at 20 la Rg, -59.0 C
 at 10 n Bg.  -«7.6 C at 5 •• flg. 8«.3 C at 1.0  u Bg
1ISSVB
*27«
»4ipo»«

•275
all*


IXIOSBIE Bonn
Inkalatlon

lakalation


kBllTIlCll
BBTBOg
ac

ac


BOBBS5
OF CISSS
1

1


BIB6B
Bot applicable

Sot applicable

(BUT
SE1I
1.7 «g/g net lit

-
3. 3 ug/g vet vt

tKtt
GEBttal IBrOIBlTIOl
CaaBtai. autops> aaapl«. gcatt 1.5
kx aft«r sniffing cooking spiay.
Bal«, «g« 13 71, at 62.5 la.
•Dtcpsies: IDIPOSE tissoj: BILE:
HOCO; B11II; BEJtT; KI9BZTS; I.ITB1;
LOISS; 4VSCIES; CBLOEIBaTEO
HDtocmcis; rmoiiii COBPODBSS
latopsT saapl*. Doatk 1.5 Ir after
:«lffltg cooking sptay.
Bale, age 13 rr, kt 62.5 in.
11IOPSIES; ItlPOSE TXSSOE: BILE;
MOOD; BI1IB: BEAK; KIBBEIS; 1ITIB;
ICISS; BOSC1IS; CfrtOSHlTID
BTBtOCaSBOBS: TLDOBItE COBIOOI95

BE7EBEBCE
Stantefer, I.e.
197-i
Joornal of Tocensic
Sciences 20 |3) sSM-551

Standefer. J.c.
1975
Jooraal of rot en sic
sciences 20(3) :S*8-551



-------
Ettaane, trlcUoroflaoro-
7«-69-a
C-C13-»
C-C13-»

n 137.38. BP -111 C, BP 23.7 C at 760 •• Hg, «.l C at »00 ll Bg. -9.1 C at 200 •• ig. -2'3.0 C at 100 •• Bg. -32.3 C  at  «0  ••  Bg, -39.0 C at *0  u Bg. -M.7 C at 20 aa Bg. -59.0 C
at 10 aa Bg. -67.6 C at S aa Bg, 8*.3 C at 1.0 aa Hg
                                                                                     (COIIIBIEO)



























TISSUE


a27«
Mood







•277
Blood






•278
Era! a





J
1 «279
1 Breath
EIPOSUBS BOOT


lakalation








Inhalation







Inhalation









1 1
1 1
1 1
1 1
1 1
1 1
1 1
1 1
1 1
1 1
1

12*0
Beart







•211 I
Ildney









Inhalation








n halation









lEUYXICIt
BETBOD

OC








Badioaetry







ec







SC/HS













6C








X









BHBBEX
or CASES

i








2







1







•
HBGS


Bot applicable








0.8-.05 ag/il







Bot applicable







Bot detected-O.Otl ag/kr













i


























Bot applicable








lot applicable









BE1E


0.6 ag/g vet vt








Bot applicable







0.5 ag/g vet vt







0.011 ag/hr







GZBIS11 IBFOBBITICB 1 BEFEBZBCB
1
1
1
Beart blood, latopay saaple. Death I standefer, J.C.
1.5 hr after sniffing cooking spray. 1 1975
I Joarnal of forensic
Bale, age 13 yr. kt 62.5 in. I Sciences 20 (3) :5»8-551
1
ROTOPSISS; IMPOSE TISSUE; BUB; |
ElOOD; BB1IB; BE1BT; KIDBBTS; I. IT SB; I
tU»GS; BDSCIES; CR10BIMTED |
BIOIOCtBBOBS; FIOOBIBS COBPOOBDS I
1
0.25 and 1.5 hr after 35.6 ag/lin, I Idir. J.
13.75 nin. Initial neasareaent, .05 I Blake, 0.1.
og/nl at 0 tlae. Zstiaated froa I Bergner, 6.B.
gtaph. | 1975
1 Jonraal of Clinical
Sabjeets weighing 63.0 and 95.0 kg I Pharaacology 15:760-770
EIOCD; TIDOBIBE COHPOIBOS; 10DIIS: |
BIlSmnSBT BRBODS 1
1
latopsy saaple. Death 1.5 hr after I Standefer, J.C.
miffing cooking spray. | 1975
1 Joarnal of Forensic
Bale, age 13 yr. ht 62.5 in. I Sciences 20 (3) :5«8-551
IOTOPSIES; 1BCTOSE TISSUE; BILE; I
6IOOD: BS1IB; BEUT; KIDBETS; LITBS; I
miss; nnscits; CHLOHEITED i
BTEBOC1BBOBS; FLDOB1BB COBPOOBDS I
Previous exposure to eoapoand. Bo I Conkle, J.P.
ether detail! given | Caap, B.J.
Cryogenic saapling technlgoe. | Belch. B.I.
| 1975
ealtky ailltary and civilian | Archives of
aployees, D.s. Jir Force School of 1 Environaental Health
erospace ncdiclne, ages 23-07 yr. 3 | 30(2) : 290-295
aokers. i
1 j
1 IIBZEHS: CBICBIB1TEB BTDBOC1BBOBS; |
1 C8LORIH5 OBG1BT.C COXPOOBDS; I
1 CBICBOIEBZIBIS: FLOOBIIE COBPOOBDS; 1
1 MEMS; tICOBOlS; THUS; 1 DOITS |
1 1
»9 ag/g vet | litopsy saaple. Deatk 1.5 hr after I Staadefer, J.C.
1 aniffiag eookiag spray. j 1975
1 I Joarnal of Forensic
I Bale, age 13 yr, ht 62.5 ia. I Sciences 20(3) : 5*8-551
1 1
1 IBTOPSIES; 1BIPOSS TISSUE: BILE: |
1 E1COD; BB1IB; BUST; KXDBETS; LXT3S; I
1 iftias; lascus: cmoEimiED i
1 BYBTCCISBOBS; FLOOSIE! COBCOOBOS I
1.1 ag/g vet vt I latopsy saaple. Deatk 1.5 hr after 1 Staadefer. J.C.
1 sniffing eookiag spray. | 1975
1 1 Joarnal of Forensic
1 Bale, age 13 yr, ht 62.5 ia. f Sciences 20 (3) :5as-5S1
1 1
I IVTCTSIBS: IIIPOSI TISSUE; Bill; 1
1 IICCD; BBiiB: asm; IIDIEIS: LITXB; i
| 11B6S; 10SCIZS; CBLOHEHED |
1 BTtBOCIBBOBS; FtOOBIBB COBPOUEDS |
1 1
(BUT PIG I)

-------
(etk»e, trickloroflaoro-
c-ew-i

*! II7'31! "JJ'J  S'  ?«23-7.c  *hTf*  ™ M'.*-9 c •* *°°
at iw •• Ha*  -«7.o  c at  5  •• H0p Ba.j C at  1*0 M 09
C at 200 aa Bg,  -23.0 C at  100 *• eg. -32.3 c at 60 aa  Bo;. -3».o C at «0 aa Bg. -»9.7 c at 20 aa Eg, -59.9 c

              (COHXB9ZD)
I13SDJ
•282
liT*T

•2«3
HM

•2M
•i«cle

Einsnit mm
XaaaLatioa

I«k»lation

iBkalatlon

lUlRICtl
nnoD
ec

oc

sc

I0BB1B
or cisis
i

i

i

IM6S
lot applicable

lot applicable

lot applicable

am
2.9 »g/9 nt it

3S «g/j wt »t

0. S og/g nt nt

eiinii nmutxoi
•
IstoptT s&ipl«. B«ath 1.5 ar attar
>al((iiq cockim spray.
B«l«, aq« 13 TT, at «2.5 la.
uncpsiis; iBirosi nssos: BH.Z;
noctj BBHI; nm; KIBRTS; IITSB;
miss: loscizs: CHIOIIHTII
(iriociiaois; riooim COB pom DS
Igtopar saaplo. Itaatk 1.5 kc attar
•ilffiaq cooking spray-
«al«, aq* 13 rr. kt 62.5 in.
inopsus; IBIPOSI nssoii BUS;
ttOOBt nut; RE»«; ttgrttS; IITEB;
tnies; 10 sens: cnoBiittn
IIB10C1BB01S; TUOKK COBPOimOS
lliopaoaa. iDtopsr Mipla. Death
1.5 kt aCt«i miltiBq cookiag >pcaT*
lal«, ago 13 rr. at 62.5 in.
inopsus; (iiFOSi nssoii BIU;
noco; BtiiB: Bum; KIBIITS; LITBB;
linos: ASCIIS; CHLOSIHTII)
StDtOCIBBOIS; riBOSIU COBPOIWDS
Btrnmct
sta>a*f«. i.e.
1»7S
. Journal of rorauie
Sciences 20 (3) :S«S-551

st»oa«t«, J.C.
1»75
Joarul of Porenslc
Sci«K«« 20(3) :5««-5S1

st»»a«t«r, j.c.
1975
Joutnal of Forensic
Sciences 20(3):5I>I-551

                                                                                                                                                                                        M
                                                                                                                                                                                        KJ
                                                                                                                                                                                        Ul
          soaie add  (8 CI)
  ccoaie «cia, MthTl-  (9 CI)
  :t-se-3
  -H5-1S-O3
  B 139.96.  BE Ul C

(585
TliM










EIEOSOB; BOOTB











IHILTIICU
BETBOD











ROB BIB
or cisss
a) 9
b) ia










IllttJ
a) tat qlm
b) lot gi?«n









	
BS1B
-
a) 1.7 ag/g
ccaatijtina
b| 5.2 u
-------
   Retkanol
   C-BB-0
   •t 32.0*,  IP -»?.§ C, BP «».7 C
IISSUI

«28«
tieatfc




«2«7
Sreatk










•28.
Breatk











ixposin* ton
































iHinxui
BBTBOD
er/BS





oc/as











ec-as












inaan
or CUES






,











5» (387
saaplea)











laKX

0.27-3.39 ppa





lot d«tect«d-2C.O of/kc











>Ot flT«B












Bill

1.0S ppa





3.7 «j/»r











0.5*9 ag/1
SeoHtcic











GsisiiL laroiaitioi

Corrected for level la inhaled air

Eealthr adults

sum: icons; BMSTntBssiT BSTEODS;
IITB1IOL
Ceitoma related to aoraal
•etabolia*. »o otler details ging
Cryo^eaic saapliaf ^ecnnla^tt.

Bealthr ailitary and elviliaa
aaplorees. U.S. air Force School of
texospace Beflcin, aqes 23-47 TT. 3
stokers.
Eiitms: caiointTEO BTDIOCISBOXS;
CBIOSHI oaeiaic COHPOOIDS;
CEietoBinziijs: nvom: coapouwss:
SMITH; itcceois: TBUS; IDOITS
ttaaared at 25 C atd 760 aa Kg
3.61 occurrence
Io«er BBS nfper one-Si gaa liaits
0.1S1 and 1.99 B9/1

a«altkr. 18-35 jt oil, QOHBackia<7.
ortaa blacks a»d Caucasians.
Ckicsgo, It. Biqidlr controlled
eipcrlaaatal coalitioaa.
IlflTI; 11CCBOLS; IILIWOIS; 1001TS;
CBtCSIHIID BTDBOCIBBOIS: »OHTH!
ciGinc coBconos; BIUTI BIIHDS:
IIB1UTIOI; BIT1MLISI: BETIEOLITZS;
topniTioi iiposraa; USBJI IEEIS
BIWSEICI

Janaaoa. B.o.
IBTSSOI. B.T.
19«9
Joacaal of laboratory
and Clinical Retools
74(K):9«1-9«6
Coakle, J.P.
Caapr S.J.
Velch, B.E.
1975
ftrckives of
EBTiroBMBtal Healtk
30 (2); 2*0-295





KrotoaziBaki. B. K.
Braaeag, G.I.
O'leill, B.J.
1979
Journal of iBaljtical
Toxicologr 3:225-23*







                                                                                                                                                                                            CT-
       
-------
       tUmllit* t» ct)
      id*. Martin (* CD
c:*-»2-o
C2-M-S2
§1 91.2,  It 109.7 C, If 26.«  II B« It 25 C
                                                                                  (conitmq
I1SSBI
•290
Bmtk










IIMSWI MHI











llllttlClt
•BTRQD
SC-BJ










OF C1SIS
54 (3*7
aaipl**)










I»GB
lot 9lT«a









	
BMl
1.9* mo,/l
Ceoaetric










6EBZB1I IBTOBBaTIOB
C«*m*4 at 25 C aal 7(0 •• tg
33. 1* occarreace
leMr aal upper oa«-Sloaa Ualts
C.M7 aal 7.M mg/1
lealtkv. It- 35 TC oli. muokiag,
ortai bltcki aid cancailua.
cticaqo, II. ilqidly controlled
tiperliettal eoailtioac.
Him: HCCHOIS! tUIMUt UHUS;
CitOIIHTZt mtOCIIBOISi TOHTHE
ClCinC COBPCBIPS; BMIT8 IKllDS;
HBlIAtlOtt BITIBOIISI; B««O11TSS:
wjniitioi zttoson: niui mis
nnmcB
Itotonnaii, g.i.
Bcneai. «.B.
O'leltl. B.J.
1979
Jonraal of aulytical
Tozleolo«f 3:225-23*







 «thil cdlflte  (9 ci)
 «thu«, tUcbl*- (« CI|
 I-U-3
 J-tt-S
 1 (2.11, n -13.2 C. IP 37.5-31 C
TXSSVt
• 291
Bnatk








•292
Bieatk











EXtosni Konti






















lUtTTICll
-IRBOI
OC/HS









oc-as











IUBBM
or cases
t









S« (3(7
•aiplu)











MICE
-
lot fletecteS-53.0 aq/nr









lot ^iTen











«..
17.6 ij/hr









Seowtrlc











SlltUt IR01BKIOI
-
Coepoeil related to lonal
aatabollai. la other details qln*
CrTOTealc laipliaq teck&l^ae.

lealth? illttatr ui ciTili«
•iploraM, n.s. air Face* School of
»ero«j>ac« Mdlei**. aoejs 23-*7 It. 3
disnts: cBioBiiiTjo BTDBOCWIOIS;
cnotin oicinc COBPODIDSI
ciiotoimms; nnoiriE coBfonns;
E1I1T9: I1CCB01S; TZI1S; 1EB11S
Pea«mred at 25 C ai4 7CO •• Bg
M.«% ocemnaca
lover nd «ipac ow-Sloai Halt* 0.*2
aid 2.30 aa/1

Bcaltkr. 16-35 TC old. noBHokiaa.
•tin bltclii aid eaaeasla**.
Chicago, II. BigldlT coitrolled
•iperiwatal conUtioia.
flZlTB; IICOMIS; IIUIOIS: IOOIIS;
cnoiiiktie iniociBBaiSi Toitins
ciemc coBpcutDS; BIU.TB IMIBIS:
uiiUTiai: RTiBoiisi: BEIIWLITH:
EQIOUTIOB ZmsgiE; BJBal 11IM
MIBMBCI
coikla). J.P.
caip, B.J.
Mich. B.I.
1975
lreki*e* of
EUTlTouatal Health
30 |2): 290-295




Krotoatimeltl, B.K.
Bruaaa, e. R.
c'lelll, B.J.
1979
Joarial of analTtieal
Toilcologj 3:225-23*







                                                                                                                                                                                   NJ
                                                                                                                                                                                   NJ

-------
ItV 95.94, If 2622 C, BP «25 C (appro*] , TP 1 •• Hg at 3300 C, 10 •• Eg at 3770 C































1ISSDI

•293
Blood,
(hole








»2»4
Siir
















IIPOSOEJ BOOT

































«295
Kidney

1
1
1
1




















1IUTTICU
RETBCD
































It





















IUBBSB
or ciSBS
w




























IMBB

0.50-15.73 ng/100 al































) * a) 0.072-0.67 tg/g
) 9 b) 0.0*0-0. «1 ua/g
c) 10 c) 0.069-0.24 ng/g
let vt


















BEtB i GEiim iirtnunoi
1
•ot given 1 lange of aeau. snltiple aaaplea fro
1 9 collection cites in the U.S.
1
1 SIIHTUS: aOIIBBUTTB: TUIDIBS:
1 HOOD; SEX: SOOTB BlKOTi: IE* TOBIt:
1 iiCBlie: mKMi: OHIO; KISSISSIPPI:
1 1II1S; SOBTB D1ICOT1; I1SHII6TOH;
1 C1LIPOSIII: lEIZOH; 1191111;
f lOVISTUl; IBM ISIS; FWBIDI;
1 TIB SOrl; TB1CI EIEIEITS
t
i Bevlev. 24 repreaeatatlve
1 pte-analysis treatunts arc
1 tabelated. The feesibiltty of a
1 holistic, no-wash policy for hair
1 analysis is oetliaed and supported.
1 ItTIEIi T*1CI EtMHTS; HUE;
I itsnuij; BiisusBsn BFTBODS;
I riTus; PFOIHIS: CORPIUIITE
1 ITllniTIOIS: 1HTBII09; lITIIOiy;
1 IISZBIC; B1B1US; BBOK1T: ClHIItlH:
1 CI1CI0B; CBIOBIRE; CEBOBIDB; C011LT;
1 CCFPEB: GII1HI": SEtBHTDB; GOLD:
1 10DIII; ISOI; UtTHiIld; Llir;
1 (IGIESTVar BlKalESB; BttCOBI:
1 iciTEDinB: IICKH; psospuoins:
1 POIISSI5B: BOBIDI0B; SELEIIB1:
I siivxa; SIITEB: SODIOH; STBCITIOI;
1 SDirjB; TII; TITHIDB; TDIGSTEI;
I inc; IIBCOIOB
1
1
a) 0.22 ng/g F a) Controls
b) 0. 19 ng/g I b) vortor grcup I
I 0. 10 ng/g I c) loiter grenp II
let ft I
edians I teceased refinery and seelter
1 1 netkers, ages 55-76 yr. exposed to
1 1 hiavy aetals 1-3 decades, liee
f f netwen retirement and death 0-1.5 yr
1 1 it gro«p I a«d 2-19 yr, group II.
1 controls, ages 43-72 yr, vho lived 50
1 ki frei the factory- sneden.
1 SI!B!»: C1D1TEIS; IIDIXTS; IITZR;
1 ICISS: C01FIUTIVE ETaHUIIOBS;
1 IIDOSTtlll BTSIEK: BBISDJBBOTT
1 9ITBODS: IITIBOIT: IBS MIC; C1DIHFS:
I CISIOB: cHBomr»f COBJLT: COFPBI;
t GOir; HOI; I1RB1IOH; LE»:
1 eiIGI«ESt: BKCOBT; HOLTBIIaim;
1 CBOSPBOBOS; BDBIDTDR; SC1IDIOB:
1 sniBin: SIITEB; TII; TBIGSTH:
1 ZIIC: BMITB B1Z11DS; IKDOSTBH1
1 PURS: SRIlTtBS: TEllmiOR
BIHBEJCI

illa«»j, I. H.
Xnbota, J.
Loses, P.
Roth, B.
1968
Archives of
Znvirouental Health
1S:342-3«t



Chittleborongh, G.
1980
Science ot the Total
EnTironnent 14:53-75

















Brnae, 9.
lordberg, G.
Hester, P.O.
1930
Science of the Total
Environment 16:13-35
















•MM PIS I) .-- ..
                                                                                                                                                                                        00

-------
 Boljbiftam
7«39-9»-7
Be
ttl 95.9«,  SI 2622 C,  Bt  41J5 C  (approi), TF 1 n Bg it 3300 C, 10 u fl» »t 3770 C
1IS5IE

4296
lifer




















4297
Into.





















EltOSBBE BOOK














































aEiimcu
BsTHOD






















U






















BBBBSB
OF CISIS
•J «
» 9
c| 10



















at B
W 9
c) 10




















E1KE

a) 0.34-1,24 ag/«;
b) 0.21-1. C9 ag/g
c) 0.22-1.33 ag/g
Vet vt


















a) 0.011-0.27 ng/g
b) 0.014-0.15 ag/g
c) 0.020-0.12 «g/g
Bet wt



















BBAB | GEEESal IBWBBHIOB
J
a) 0.5* og/j | a) Controls
b) 0.65 aj/g j b) Vorker group I
c) 0.4* eg/g | c) Borlnr groap n
Vet «t I
Sediaas j E«c«as«d refltery aid iMltet
1 workers, ages 55-76 yr, exposed to
j leavy aetals 1-3 decades. Ties
I tetween retireseat and leata 0-1.5 yr
1 la group I and 2-19 yr, groap II.
I Controls, ages 43-72 yr. HBO ll«ed SO
I ka fros tbe factory. Swedes.
1
1 SBECEV; CIDIfEBS; KIBBBTS; LITEB;
I 1VICS; COBPlBaTITB CTIIDITIOBS;
| IBtOSTEIal BI6IEBB; BIISOBIBCTT
1 BiTWBS: iniBOBi: wsnic; CIDBIDB;
| CESIBB: CBBOB3HB: COBaLI: COPPEB;
I SQID-. IKOB: laBTBlBBB; 1I»I;
| BIB6HSSE; BEECDB1: BOL13SEIOS;
| SELZEIOS: SIITEB; TIB; TOIGSTEI;
I IIBC; BE111B SlIltDS; IBSBSTUkl
| PI1BTS; SBEltltS; TBlLDBIOa
a) 0.030 og/g \ a) Controls
b) 0.027 ag/g I b) Barker groap I
c) 0.053 ag/g | c) Barker grcap II
Bet «t |
lediaas | Ceoeasei refinery aid snalter
| Markers, ages 55-76 yr. exposed to
I keary setals 1-3 decades, fine
| tit Men retirement and deatb 0-1.5 yr
1 IP groap I ail 2-1* yr. qroap II.
I Coatrols, ages »3-72 yr, >bo liied 50
1 kn fro* tbe factory. Sneden.
1
| SIEBEB; CaOlfBISi HIBI1IS; tITEl;
| IUI5S: COBPUITITS ITllUWIOBS:
| IBCBSnill BTGIEBE: BEISHBEBEBT
| SITBODS; tBTlBOBT; USIBIC; CUBTVB:
| CISTOI; CBBOaXBB; COBILT: COPPEB;
I SQLC; ISOB: il«TBi»OB; ISaC;
| BlBGtBISE: BE8COBT] B01TBDEBOB;
1 traspBOBus; svaioiai; scaioins;
I SltElini; SHIEB; Til: TOBSSTEB:
1 IIBC; BEalTB BailSDS; XBDOSlBIal
| PIlaTS; SBE1TEBS: TEllVBIOB
UFIIEBCS

BEtt&a, D.
Bordberg, G.
vaster, P.O.
1980
Science of the Total
EcTlroBicnt 16:13-35
















Bm&e. D.
lorjberg, s.
•eater, P.O.
1980
Science of tae Total
EiTtronneat 16:13-35

















                                                                                                                                                                                        KJ
                                                                                                                                                                                        NJ
                                                                                                                                                                                        VO
 Bapnthalene
 91-20-3
 C10-B8
 «I 128.16, BE 80.1 C.  B? 217.9 C.  TP 1  ae Hg at 52.6 C
IISSttE
4298
treat*












BirOSBBB BOOTE
-














imnicii
BET BOD
«C/BS













BBBBES
OF C1SBS
B













B11GE
Bot detect«d-2.» og/kr












(tin
8EAB
0.5 »j/hr











•
PISE)
GEIE81L tlPOBHTIOB
Ftflilots exposure to coipound. Bo
etner details qlTen
Cryoqeolc saapllat tecaniqae.

tcalthy nllltary and ciTiliai
eaployees, U.S. air Tocctt Scbool of
lerospaee Bedlclse, ages 23-47 yr. 3
linkers.
EIBZEBtS; CBIOBIHTfC BT9IOC1BBOBS ;
CE10H»! OBG1BIC COBPOtnilS;
CBIOBOIEIZEIES: FIOOTHS COBFOVBOS;
EII1TB; atCCBOLS; TE»S; ICO ITS


BSFEBEVCX
_ .. _
conkle, J.P.
Caap, t.3.
velch, B.E.
1975
lech ires of
EKTironaental Bealth
30 <2J! 290-295








-------
   Etpkthalanc
   SI-20-3
   C1C-H
   «V 12*.1C. IS 80.1 C, BP 217.9 C, TP 1 •• Hq at 52.6 C
                                                                                        (COBTIBDED)
TISSUE
«2»9
Snatk













nPOSTOE HOOTI















IBIinXCIL
BBTBOD
60-a s














EVBBBB
OF cms
54 f3»7
aaaplcs]













EtIGS
lot alra












I
I
«u
9.772 as/1
Seoaetrlc











1
1
6EEZB1L IBTOBBITIOE
••••ami at 25 C ud 760 n Bg
98.9V occnTraaca)
Io»*r and apper OBB-slgaa Halts
0.335 and 1.T« ng/1

B«altkTr 11-35 JT tit, aoaaaoktog.
•tin blacks aad caneaaians.
Cklcago, II. tiglllr controlled
«rla«atal coaditiogs.
tltlTR: UCOBD1S; IIIHOIS; 1DO1TS;
ceiotniTio nomciiBois: IOHTHS
CI6IIIC COBFCOnSi BE11TH BtZtBCS;
IHIlIlTtOI; tETlBOlISB; BBTIBOLITSS;
PCP011TTOI IIPOSOBE; OMH 1BE1S

1E7EIIICZ
KcotonyBaki, B. K.
Bcnncaa. 6.1.
O'lWlll. B.I.
H7»
Joaraal of iBalytical
Tozioologr 3:225-2M







1
I
  lapattal«ii«, dlivtkyl-
  mo*-ae-a
  cii-Riz
  >• 156.23, « T.CC C.  BP 2«8 C
IISSUB
*300
Bnatk












I
BXPOS0U lOHTB














IBU.TTIC1I
HRIOD
SOBS













1
•OBBEB
or cisis
54 <3tT
saaiplas)













BM6B
lot giren














BB1B
0. 079 og/1
^eoaetric











GE1II1L IITOtllTIOB
E«a*tc«4 at 25 C aid 7(0 la Bj
36.2V occncMBce
lowac aad acpar one-Slgaa Halts
0.029 11 a 0.22 19/1

Bcaltk;, 18-35 re old. aonsaoklag.
actan blaclES aad caacasiaas.
Chicago, n. Bigldlr cont rolled
expeclaeatal coadltloas.
EBtHB: 1ICCBOLS; IILIIOIS; IOILTS;
CBIOBMITCI STtHOClBBOIS; TOHTI1!
CIG1BIC COBPCDIOS: HB1LTB BlUfES;
IlaillTIQI; BETIBOUSB; BBMBOIITSSi
f ICPWHTIOI HPOS9K: IFUIB 1EEIS
BBPIIETCE
Kcotostpuklt B.K.
Broaeai. S. B.
O'leUl. I.J.
1979
Joaraal of analytical
Twlcologr 3:225-234


-





1 1
                                                                                                                                                                                           Ni
                                                                                                                                                                                           UJ
                                                                                                                                                                                           o
Bagataalaac. antkrl-
1321-9*-*
C11-110
» 1*2. 8P -22 C. BP 2M.C C
nssiB
•Ml
Bc«atk










1

EIPOS»E BOBTE














IU1IIIC1L
BBTBOB
GC/BS











1

BOBBES
or cisss
8













iUGB
Pot d«t«ct«4-2.3 ag/hr












(•in
BEaB 1 eiltllL IlfOtBlTIOl
1
0.3 ag/kr 1 toapona frca aakaon origin. Bo
1 ether data lie glT«n
1 Crroavale aaapllaa taclnlqae.
|
1 taaltkr allltarv aad clTlllaa
1 *aplOT«as, U.S. lie Torce School of
1 l«raspacc B«Jlci««, ages 23-47 jr. 3
I >aok«ts.
I minis: CBIOITB»EO BIDIOCIBBOIS:
I cnoiiis oieinc COBMOIDS:
1 cnotoBEizziis: TUJOHIE COBPOOIDS;
1 I1IMB; alCCWLS; THIS; 1C01TS
1
VfcBC)
BEfEIEBCI
ceakla. J.p.
Caap, B.J.
Mlei. B.E.
1975
IrcklTcs of
EaTlroaaeatal HeaUk
30 (2J; 290-295




1
1


-------
fapataalene, MtkTl-
I3J«-»«-»
C11-114
It t«2, H» -22 C. IP 2M.6 C
                                                                                     (CORIiniO)
txssvi
»302
Btwtk












IHOSOB BOOT1














alalTTXCU
HBT8O9
0C-IS













miBR
OF CISXS
5* (317
•Baplas)












BITCI
lot : ncoBois; IU.HOIS; UHLTS;
CB10BIHTED BTDBOC1HBOIS; TOUTILZ
cteinc COIICDIDS: nuia BIIIBCS;
11BH»TIOI: ERIBOIISli BBIJEOimS;
FOftlUTIOt llfOSBIB: HHB1I 1B11S
txntxtcs
Krotoszjuki, g.K.
Brueav, G.I.
0'*eUl, B.J.
1»T»
Jotimal ot kntlftlcal
loilcolo^T 3:225-23*








llelnl
1«*0-02-0
II
Itl 5*.71.  If 1«S5 C. BP 2*31 C, re 10 •• ig at 2090 C,  100  mm Sj at  23TO C
Tissue i nposmi SOVIE
i
1303
(loot.
pl««a

• 30»
tlood.


•305
Blood.
pl*s»



XtbaUttai




iuimcit
IBTBOD


US


us

IOBBEB |
OF CISBS


«} 1
b) 1


6

1U6E


a) 3.0-4.0 «g/l
b) 2.5-9.5 as« caoc«r in practical
tipomc* cltMtlois. the a««4 {or
dos« r*fl«tratiOB i* capitalized.
ICIIkT; CIBCHOBIS; BLOOD rllSll;
DIXIE: tiBasxsxu. neitn-. nrm:
cnomi; a MILS; ncxn,; citciKGti;
IlDISTtlll UMSFHXEES: IIBDSTIIES:
cccopinoin >»»DS: IBOPHSBS
at Barker axpo*ed to last of
Imolubla 11 coapouls. Blniial
dlirail variatios
b) lorkat eipoMd to a«to«clt of
tclmbl* (i silt*, eradnal rise aa
4ay pro^ccsKl
Sellers i» roastlag-im-altiag SB a
electrolTttc tooactceats In lornr.
•mis: iicuH: •OBI«; iicflsriiu,
ITBOSP9BBBS; OCCOPiTIOHl BMIEOS;
neon msii: mitt
a) Erot«ln-pMcifit«tion aa*ple
preparation
t) acid-digeatioa saaple preparation
c) ProtelB-pnclpltatloa 
                                                                                                                                                                                          LO

-------
lickel
1MO-02-0
li
lt» 58.71, Ht 1«5S c.  BP 2637 c, TF 10 »  Bg  at  2090 C,  100 »  Bg at 2370 C
                                                                                    (COITIHOED)
KSSOS
• 306
Blood,
serna
•307
float,
•hole
•308
ireata
4309
Bltaeaii
• 310
nic
EIPOSIU son
Ingestion
lagestion
Xakalation


1 MI men.
IETHOD
IIS
us
PIK


TOBBSB
or c»szs
i
*
i


MIGI
i) 0.3-3.* ag/1
b) I.S-105.0 aa/1
a) 0.t-«.S ug/1
b) Z. 9-79.0 «g/l
lot gireg


aiti i GEEZBII IBPOBBMIOB
1
>) 1.60 * or - 0.93 I •) Baaeline »l««s
14/1 1 t) Wats, 2.5 hr after 5. « ig as
b| 33.9 » or - »3.9 I solfate
og/1 I
1 acalttr 21-32 rr old
j BO ««tal hTP«r*easlti*itr
1
| S«IOB!t; IDOLIS: BIOOO: BIOOO SEIUR;
| DII»: IICEEI
1-
a) 3.25 + or - 2.33 1 at Baseline Talus
09/1 | b) Peaks, 2. 5 hr after 5.« my aa
b) 2S.7 * or - 31. 5 1 tilfate
nq/1 (
1 Health t 21-3! re old
| 10 letal fc7p«r*e»ltlTitr
1 siBDZT; >DHITS: BLOOD: BLOOD siaaa:
| DIXIE; nCKEl
1
23. 1 ag 1 « 1 stapled at rat* of 1 1/ali, 2-10
| iln after tuning a arc vcldlag rods.
1 OniTersitj physics shop, Vlocida
1
1 flOIIIa: IBOLTS; BBZaTR; C1LCIOR;
I cnotiiK; cnonoi: COJPH; moi;
I iiJB: *»6»csB; ncrai; POIISSIBB:
I S01FIB; TITlllm; TIUHOa; H»C; 1IB
1 potiini(H: rtms; I»OSTXZJL
| KROSPHHES: TStCI ElBSEItS
1
t
1 nriev. Pcotl«» la risk analrsis of
I cancer i» It and Cr iidastry are
I prvsentvd* Tarioas coapoands ace
I cited vkieh eaase cancer in practical
| «lpos«ce aitnatioaa. The> need foe
I dose raglstration is e«ph«si»d.
1
1 ICBVIT: ClICHORtS; BLOOD PI1SR1;
t miisi iiDisniu Breinii SITIWJ
i cnomi; tmis; itcsn.; ciBcinsni
| TIIOSTtlil ITflOSPHEHES : IBCISTBISS;
1 eccipaTiovtt BaziiDS: «!OPi»sas
1
1 Berie*. 2* npresentatire
1 pr«-aialr«is treatamti are
I »•*«!» ted. la* f«asibilltT of a
1 aclistic, ac-vtsh poll c 7 for hair
1 amalyaia is cctliaed a>d serrortod.
1
1 tfTXCT: TPICI nmin: HUB;
1 losTBitii: msamsrr svtmes;
| IITUS; PBOTEIIS: COHP1B1TITE
1 ifiiuMiois; uvBnoa: miaviT;
| IBSniC: BilltJH: BBOHIfE; CIEBIOB;
1 cuciTjs; cBLOtnt: cnonvi; COBILT:
1 CCPTEB: enini: cisiiiina: eoti;
| lODMt; ISOB; LlintlDB; l»»t;
| HS1BSHS; B1K1BESE; IEBCOBT;
I tCHBVnOBs ITCKCl; PBOSPBOBOS;
| MtlSSIIH; BIBIDIBI: SSLZIHB;
1 mico*: sutti: somiB; STSomtm;
| SDIMl! TIB; TITIIIDS; TDISStZB;
I me: IUCCIIUB
1
BZFEEEBCX I
1
Ckristeasen, O.B.
Lag«ssot, V.
1)81
annals of Clinical aad
laboratory science
1ir«s119-125
Christeasen, O.B.
lmg»asoa, T.
H81
Innals af Cliaical aad
laboratory Science
1t{2»: 119-125
Ikselsson, K. B.
Desaedeleer, G.S.
Johausoi, T. B.
Bincftester, J.tt.
197S
Innals of Occupational
B»gi«ne 1»:J25-23S
varaeth, I.
1*80
Joaraal of Toricoloo;
and EnTironaiental
ff««lth «<5/*|: 12 W-1227
Chittleboroagb. S.
19 SO
Science of the Total
EDTicouent 10:53-75
                                                                                  (BtR

-------
flcxel
1*40-02-0
II
»tl 51.71. n 1*55 C. BP 2*37 C, Wt TO M Bg at 2090 C. 100 ll Kg at 2370 C

4311
Bale


4312
Orlne

4313
Brine



4314
Urine












Inhalation


HETBOD





US .



us


•OIBBB
OF C1SXS





al 35
bl 18
c} 68
d] 33
e) 32
fl 11



a) 1
b) 1


SIRS:





a} <10-90 og/1
bl <10-IO ag/1
c) 10-200 og/1
d) 20-130 ag/1
el 30-110 ag/1
f) 30-120 ag/1



al 13-54 ag/1
b) 25-47 ag/1


8 Ell





al 28 or - 10 ag/1
b] 3D or - 20 aoyl
c) 65 or - 42 aq/1
d| 52 or - 31 ng/1
e) 68 or - 31 19/1
fl 70 or - 30 e»/l



a} Bot given
b) lot given


enroll UTOBBITIOI
1 review of sorld literatare oa the
accvnlatim and bioconcentration of
(elected toxic trace setals in h1 and Cr industry are
presented. Tatioas conponnds are
cited «nlch cans* cancer in practical
exfossre situations. The need for
dose registration is •aphasized.
ICBS1T; CIBCIBOatS; BLOOD PItS»:
OIIIE: iieisniu HIGTHE: BCTICT-,
CEBosns: »TU,S; no; EL: CIBCIKHSEB;
IBOOSTBIll ITMSIBZBES; IIDOSTBIES:
CCCOflTIOSU BK1BDS; XEOPUSSS
a] contmls
c) Besearchers, ainiaal Bl exposure
c] Prodtct Sorters, soluble li
d) Caleiaers, »l dust exposoce
e) Extractors, exposed to dast and
f) tester plant, ll oosder and li
carbonyl ass expasare
Values corrected to l.t q/1
creatisiae. Data also for
ataospheric dost.
11 refiaery «orkers, 19-C4 yr old,
petro-cheslcal sorters as ccetrola.
IICKIU HITltS; UDOSTEIAL PHITS;
DUST; mm; UIITED KHGDOB;
cccn;»io*ai nzutos
a] Sorter exposed to dast of
insoluble Bi cosponnds* Peak at 10
at
t) sorker exposed to aerosols of
cclable (1 salts. Pea* at 11 as
Dlaraal variation in bats.
Ictksrs in coastina-sseltiia and
electrolytic departments in (orvay.
amis; IICKTL: KXCIT; tiiosTBiu
I1IOSV9BBZS: OCCIJPITIOHL BltlBDS;
IICCD F1ISR1; OBUE
1ERBEBCE
Jenkins. 0.*.
1»79
IP»-«00/4-79-049, 1»4
PP.


Borseth, T.
1*80
Joornal of Toxicology
and Environaental
Health 6 <5/6| : 12 19-1227

Horaan, L.S.
Eouge, P.J.C.
197*
annals of Occupational
Hygiene 22:311-317



BogetTeit, I.e.
Barton, B.T.
Indersen, I.
1980
Journal of Occupational
Bedlcine 22 (91 =597-600


(MM FIG11 •"' 	

-------
    Ilckcl
    1MO-C2-0
    II
    Itf 5*.71. IP t»3S C,  W  2«7  C, W  10  u  S*  at 2«0 C.  100 •• Hf «t 2370 C
                                                                                        (cortmrsD)
TISSII
«315
•rtaa
«316
OElM

EIKWiil tO«TE



MUniCU 	
since
us
us

* " cram —
or cists
is
*

1IK1
t.9-9.6 u«/l
_
*) 0.3-3.* WJ
b) 17.7-202.0 tg

m» '
*.*5 » or - 1.9 BO/I
a) 1.5* * or - 1.99
b| 69.56 t or - 59. «
••5

ctimi iiroiiHioi
Etctota-pnclpltaUoa saspl«
pctpacatlOB
Maltkr 29-«7 yt old*
•OIMT; IDBtIS; HOOD niSHl! OSII1:
CCBValtTlfC ZTIlnTlOIS; fllaSfflEHSR
inioDS; tiauniminoi; IIDUSTEIII
taissio»: ncni: BETIIS
•
tl m«r «.« B4 i> nlfato
nalUr 31-31 re aid
smii; IDDIB; BUM»: suxa iirra;
onti: ncm
B'smcs
Torjuuo. I.
Zackarlaaa, H.
cllalcal Chaalrtrj
2* (7) si 19*- 1202
-
CBElct«M«B, O.B.
t9*t
•aaals of Cllalcal aad
laboratorr sdaac*

  111-84-J
  CJ-BM
  M IJ8.25. BP -S3.7 C. M ISO.T C. TP 10 •• B9 it 3B.O C
nssot
1317
Irvatk












tinsras tofTf














•UtTTICIt
BIT BOB
OC-IS













imun
OF C1SJS
5« tJ»7
•aipl«s|












MMI
•at «iT«













IUI
O.J48 15T/1
s*«Mtric












eillUl IffOMHIOl
B«a«u»d »t 25 C ail 760 •• B licit*
C.0«* aii 1.J7 14/1

SMltbf. 18-35 yr old, »OB»olilBg>
•TtM blacks aid caicatlans.
Ckicifo. 11. Ilqldlr cg/l

GIIIUL nroiittiof
M«nr*4 at «Bd of working i»j, f«aa
ale Ionia 10-13 BIB.
laboratory aasistaats «orkla« clta
ocqlalc solrtBts.
CCCWII101H utitm GSMatt:
»Ml«; BU>01t CatCIBoen
timnct
l«1m«rt, 6.
latacBBtloaal arcnlTos
of OccapatiOBal aaA
BBTltOBMBtal IMaltfc
• 3-.1W-150
                                                                                      (tin

-------
          i en
NBZ*M, 1.2-4i«Url- & CI)
ct-no
II IOC. 1C, IF -IS C. « 1«« C, TV 10 •• Ig tt 32. t C
                                                                                   (CORIIDIO)
tissn

Bnatk










•330
BriB*














mosaic Bons












tBaUaU..














luimcu
BBTBOD
ac-is










•nc














nmt
or cms
5* on
«BDl«)










Bt *
b| «
O 2












_
BUM

Bat giT«










•) Bot git«B
b) lot gins
e) 0-0.1* ag/Bl













Bill

1.0 BO/1
saoBatclc










a) 0.0037 * or -
0.0007 i»»l/kg CM ot
toM)
b] Trie*
Ct lot ftTM











BCBIUI UTOBBHIOB

e Bg
lovK aad «PP*r o»»-Sliaa Halt* 0.36
aa* 2.8 Bg/1

BBBltM. 1«-35 TT DU, BOBIBOxiBg,
irtai tlacfeB aad caacadaaa.
Caicago, 11. Bigifly coatrollvd
«p«rli«BtBl coadltloB*.
IBEUI: IICCBOL3; IIUKHS; IDOLTS-,
CBLCBInlBB EnBOCaBBOBSi TOUT 115
CtGliTC COBPOUtBSj BUUB ItUIOS;
IIBlUTIOBl BXTMOLISa; iniBDimSl
'
a) o-Tolaic actd gl««BcoBl4«
(aatabol.lt*), 2B kr «zcr«tiw att*r
0.3*1 BBol/>g o-zTl«lw, oral. Paak
la 3-< be
E) o-lolalc add glvCQCoaida, att*v 3
ti «xp«*«x* to 13* ppB tr-irlcaa
c( p-BBtkn*ipB«rle Bell
(BBtBbollt*), attac oecnpttloBal
«*POCBC« tO 17l«.B*. B«tiBBt«d CTOB
9Kapa
telBBtOTT** aaaa »a« S3 ft total).
nl »* rr (vapor). f»lBt«r« in
aaippatldiBg rard, a«aa ag* 32 jr.
HUB: iRIBGUTIS: tllS;
eccwHioBii iiittDS; wminoB
tlPOSOU: 1K1TL HBRlLSj P1IB1S;
1IIUUIOB
mctnci

KrotoniBBkl, B.K.
Braaaa, e.g.
O'Belll, B.J.
1979
Joaraal of laalytlcal
Toiioologr 3:225-23-*






Ogata, B.
TaBazakl, T.
Sagikara. I.
SblBBla, T.

1980
lataraational areklra
of OccipatloBal aa«
EBTiroiaeBtal Boaltk
*6: 127-139







                                                                                                                                                                                       U)
                                                                                                                                                                                       Ul
 cctaa«
  111-CS-4
 CI-BU
  tl  1U.21. B» 5t.« C, BV 125.B C,  TV 10 •• B« at  19.2 C
imti
«121
Bt«ath











EttOSOB lOOt I












taunicu.
IB1BU1)
OC-S3











BtBlZB
oi cats
5* (3B7
•»»!••)











laKB
lot glit*











Bill
0.296 ag/1
e*o««tcle



'







cBimi iipOBamaB
. _
8«anna at M C ul T60 aa Bg
21. K oecnme*
loaac ud IPPBC oa*-Slgaa Haiti
D.079 *>d 1. 10 ag/1

Kaltar, 1S-35 re old, noBtBoklag,
»tu blaeka aad caaeailan*.
Ckleaqo, 11. ttgiAIr ooBtnlKl
•*P«rlMBtal oaBditleai.
EBEITB; 1LCOK>1S: ItlllOIS: 1DOMS:
CnCKIaTBD BTOtOCIBWISi TOIaTIU
cHinc coBPtmns; IULTB aiuics-.
IIBUITIOV; BKIBOIISI; mUOlRBS;
tatmma* tttonn; »BU MEIS
_.-._,
IfcfBBIlCE
Kcotonfa*ki, B.I.
axBaaa*, 6.8.
C'Belll, E.4.
1979
Jooraal of taalTtieal
Toxioologr 3:225-23*








-------
  Cctuolc acid,  peatadecafliioio-, aeaonUe salt
  3(25-26-1
  Cf-R-T15-02.B3-I
  BS  430.98
1ISSOB
4322
Urine









t

EIPOSVU BOOTE













• U1TTIC1L
HETBOD
ec












BOBBES
OF CISBS
1












SIEGE
a) lot applicable
b) lot applicable
c) lot applicable










Hill
a) 387 eg/24 he
b) ITS 19/2* hr
c) 80 ug/24 hr










GSIIBll IITOIUTIOI
•1 1 »k
b| 3 10
c) 14 M
Interval follo«ia
-------
                CI)
               . «-(t-MtkTl«tkrl|-  f» CI)



II 150.22, Bf 2« C, BF 2«» C, T* t »  Ig  at  7«.2  C
1ISSII
•125
Srtatk












citoswv Bone














uumcu
GC-BS













•DBBIt
or CISTS
5* (317
•aaplfs)












UIG1
lot giT«













till
._
0.2«1 »9/l
GaoMtric












Gimal IITOIBMIOt
l«a»r«4 at 25 C aid 7(0 n 89
It. S* oecwraBO*
lewt »»1 vppn «a%- slga*, lliiti
0.03* aad l.ti Bg/l

••alt-VTi 1%— 3S yr old* BOB8BOkiii9r
attn blacks ud eaaeaslau.
Ckicaqe. II. tloiair coBtrvjUad
*icaria«Btal eaBditiont.
E1I1TB; ttCCBOI.!; IlXIfOIS; IDBITS;
cnoiinTti miocaiBois: TOIITILI
C1GMIC CO8PCOID3; HH1TB B1I1IDS;
IIBltkTICI: SIT1KJIIS*; BETIBOHTBS;
ropouTiot uposm: onii tins
unmci i

Braiaaa. S.a!
O'Mill, 1.3.

Jonraal of IMljtlcil
7oxicolO9T 3:225-234








I-Di«XtM  It CI)
1.«-Iioxtce  (» CI)
1J3-»1-1
C«-I«-02
11 €1.10.  » 11.80 C. IP  191.1  C.  T; »0 •• 19 *t 25.2 C
tiss«
Bnatk

Bnatk


titosui JCHTI





BMBCD
ac/as

ac-gs


or cisis

- - -
5* on
sMplatf)


I1IE1
tot 4*tactad-0.a| ag/br

lot 9lwu


Jill
0.05 «g/kr

0.253 ng/1


eiinii iiratnnoi
CcifovBi r«laua to aonal
Mtakollca. 10 etkar tetail* gl»»
CiTogoic aaipliBg tackolgB*.
laaltkr illitarr mi ei*illai
aaplor««a, o.s. ale Foce* School of
Mraapaea BcdielB*. ag«* 23-*7 yr. 3
nolacs.
IlltZISS; CHOtlllTBD RDBOCHBOIS:
cnmitt fiKjnc COBMIKDS:
ciLCMBtnnis: nnotiij COBSOHIDS:
EIUTI; 1ICCROIS; TB1U: IDCITS
!«aanat at 2S C »m« 7«O ma 89
21. B< occnnne*
lame »nd upper aa*-SiqM lliits
0.0«7 aa.1 1.37 Bq/l
BaalthT* 1B-3S TI olt, BOBiMkUg,
CUcaqo, 11. tlgldlr coatioll«4
«ip«cta«Btal coiditiog*.
{111*9; ilCOBOiS; IILIKIS; 1D01TS:
CIIOIIUTtD RBMCtlBOIS: T01ITHI
tisnic coitcnDS; nun BIZUIIS;
IIBlllTTCI; aitlBOlISB; attlBOimS;
fopntTioi IDOSVR: otan mis
HTXRffTCE
Coakte, J.I.
Caap, B.a.
**lea. B.I.
1»7S
lreklT«0 of
ZavlroBBCBtal Rcaltk
30(21 :2«0-2«5

CtotonjBskl, B.X.
D'lallli *••>'.
•\m
Joarasl of taalrtlcal
toxleologT 3:225-23*


                                                                                                                                                                                              OJ

-------
                      (I CI)
   Cyclokoxcaa, 1-B«thyl-4-(1-Mtkyl*thmyl)- (9 CI)

   C10-B16
   If 134.23. K 174.6 C. TP 1 u Bg at 14.0 C
1I3SOB
432»
Bxoatk











BXNsni toni













1I1LTTICU
HBTHOD
OC-IS












tana
or CUES
54 (387
•aipics)











S1IGS
lot givra












BUI
2.9 ag/i
6«OMtrle











6SIZB1L ICFOBUTIOI
Ma«U*4 «t 25 C »d 760 aa Bg
94.5* ocetrrwc*
lowtr aal ippar o>*-SiqM limits 1.07
•>4 7.9 B9/1

Icilthr, 18-35 TT oil. aoBSMkiag.
irtan blacka ud CMCuicu.
Ckiecfo, n. llgUlr eoBtroll«d
«sp«rlimttl coiditlOB*.
Ellin: ILCOK>LS: IILIKISS IDIHTS:
CtlOBIUTIV IIDBOC1BBOBS: TOI1THI
cieinc coircons: HMITH usues;
IHItlTIOI; 8R1B01ISI; BBTUO1RBS:
loraimoi nnsoii: HIBM tuts
nnBEBCB
KZOtOSTIBSki, 3.K.
Br«B«fta« G.H.
C'Klll, B.J.
1979
Joarial of faulytleal
Toxlcolegi 3:225-234


'




   -»k««Tl*»«Uula«  C CI)
    4-SnMMdlailM  |9 CI)
   106-£0-3
  C6-M-I2
  II 108.7 C, H 1W C. BP 267 C
IISCTB
4329
orlM













BXPOS0B BORI














.
1U1RIC11
•BTBOO















IV1BBB
OF CUBS















11KB















mi















6EIEBI1 IirOIUTXOB
l«Ti«w. Xocil ui *TSt«iic «f fccts
c«l«tli9 to kair IT* fonalatioi.
l*4t«dl««t testa, til •xp«ti«ac«a In
IIB and aiiials.

Cmtaet 4«riatitis it uan. tktir
tfoiMS, dcatists or etlwra in
ccataet vltk tcecatly 3l*& hate.
Iaa«dlat« krp*rma*ltlYlty
lirticacia) ivpoctei.
ItOHSi DBBIKITISi IBOPI1SHS; BSI««;
II TITBO II1ITSIS; II TITO 1111 ISIS;
IZTIBV; DIBS; CUCIIOSEB: COSBITICS;
SIIBTIC BFrBCTS; nUTI I1Z1B9S;
IIT1BOIISR: IR1BOLITBS
BBFBBBICB
larziUll, r.t.
6re«a, S.
•alback. B.I.
197*
Jovraal of
BaviroBBoatal Pathology
and Toxicology
1! 509-530







                                                                                                                                                                                           U)
                                                                                                                                                                                           oo
F-Tolulfakyte (« CX)
Hnxalookyl*, 4-Mtkyl- (9 CI)
104-B7-0
Ct-»8-o
(I 120.16. BP 204-205 C
IISSOI
•330
Btaatk











t
I
BXPOSDIB BOnX















iiumcu
HBTBOD
OC-BS












1
t
BOIBZB
OF C1SBS
-
54 (3*7
M«pl«S)











1
»
111GB
lot glT«n













I
BB1I
J.3 »g/l
SeoMtrie












1
6IIIB1L IirOBUTIOl
laasvrod at 25 C a*4 760 •• Bg
!.7f occirrvac*
Ic«r aad ipp*r OM-Sigaa. llaita 0.7
aa4 15.4 ig/1

l«altkT. 18-35 yc oH, soaaaokloq.
•ttaa blacks aid caacaalaaa.
Chicago. XI. ligidly controlled
aip«rla«atal coaaitloM.
(1BRI: HCOB01S; lUXKIS; UHIIS;
CnOlXHTIB IIDBOC1BBOIS: TOtlTILI
CIGWIC coBPcnDS: IUITH iituns;
mtllTIQl; IBTltOLISfl; ItlUOLTTES;
I (O?«U1XO« CnoSVR; «BB» HEIS
1
SZRMICB
Krotoaxyuki. S.It.
Braaoaa. 6.B.
O'H.ill, B.J.
1979
Joaraal of analytical
Toxicology 3:225-234










-------
      «»a  («  co
IUMM,  1.4-41actftrl-  19 CI)
10«-42-3
CB-B10
•I 10C.1t. «f 13-1* C, n 137-138 C, »* 10 II B9 at 27.3 C
TISSUE

•331
IlaoS





4332
Cnata










4333
traata












sitosrac sons

lakalatton
































11U.TTICU,
tames
oc






sc/is











SC-BS













mnxi
or CUBS
*






*











5* (3*7
saapl**]












11161

1.04-1. (9 tg/i






lot 4«t*ct«a-0.»03 ig/hr











lot 9l**a













m*

1.3075 »o/l






0.000* oaAt










.. -
3.1 ng/1
SMMtcic












6IBHU, nromixoB

It p»r« » Mta, Ma*u«d «t od of
forking 4a|. B«u *lr !«•!< 5«-6«
**•-

CCCIMTIOIII BI111DS; SB1B1II;
HULTS; BLOOt; CUCItOUII

Ce«poi«l ftoi ukion oriqla. >o
«th*r 4«t«ll« qlnc
Ciragvmie «ipliiq tcehxlqo*.

Bmltkr illltacT ud clTilUs
«iplor««9, U.S. lit Force school of
l«nsp*c« ••fllciM. «?«s 23-**7 jr. 3
iiolwn.
tlllltfS; CBIC1HKIB RDIOCUBO1S:
cBioint oisinc coiMms;
CBiciosmnts; nooitn conoviDS;
HiiTB; iicoBois: THIS; icnvs
I«*>drtl «t 2S C «*a 7SO •• Bg
9t.7< oceoTTcne*
lenr M4 vfpct OM-slqu llilti 1.2
»4 7.4 B9/1

BtaltkT, 1S-35 yr aU, noacMfclng.
ntu bl«ck> Mi nietslu*.
Ciiragot 11. liqidlT ca»ttoll*A
«lp«tlwit«l co*tttio»s.
Itlltl; HCOBOlSi IIIIIOI3; lOOltS;
tBtotiiiTiB iraiociiwis: foums
aiamc coRfcnDS: HILTB IUUDS;
HBiittia*; reritouss; IBTUOLIRS;
icmnTiof inosiu: D»B»I usts
itrisnci

tnq*»r, J.
I«Ia«ct, 6.
H7»
Interaction*! icchlTca
of Occvpctlonal ana
initoaMBtal B«*ltk
•3:154-150
CoukU, J.P.
Ca«p« B.J.
Mich. B.I.
1»7S
liefeln* of
fariroBMntal B««ltb
30 (2): 2*0-295





KrotoczfMki, B.K.
Braa«a*« 6. B.
O'Mlll. B.J.
tm
lonnal of laalytleal
Toxicology 3:225-23*








                                                                                                                                                                                            to
  1440-05-3
  I«
  It! M«.4.  II IMS C,  « 3167  C.  n 1 aa Bg at 1*70 C.  10 aa Bo at 2290 C
IISSOB
«33*
lAlBOB*










IHOSDtl WJBTl












HllRXClt
BETBOD
US











10B1S1
or casts
10











(1KB
- -
Bat gti«a









.
{•in
SEtl
O.« pnb









.
rteo
eimti nroiBMiOB
.
loa k«7«l«« nciteat*

UtopiUa, 12-79 rr olds.

ntus; pnumB: PIILIDIOII: isu>s
TOfDllTIOB BimSOIB; OCCONTIOBU
Bixites: cunosBii: iirropsr«s;
HOOD; 1IDKIS: SniBB; Bill; D1I1B:
HISS; «VSCltS; UIMSB TISSUI;
HTM! COBtlUNfB EIliH«IOlS: BS<
onsiT: calm; BIS»B: IOTOBOTITB

•EtEtXBCB
Joha*oa. O.E.
Fc«*oct, J.J.
T111«T. l.t.
Caaaaa. 9.1.
(OMafela. J.B.
197C
B*»-«0«/1-7«-019. 235
PP-





-------
tainau*
7MO-05-3
n
Itl 106.*. at 1S55 C, If 3167 C, TP 1  aa Bg at 1*70 C,  10 M Bg at 2240  C
                                                                                (comnsoi
IXSStll
1335
Hood
•336
lilr
•337
XldMT
•33*
1 1 MI
xxtoson tooi

1
1
1
1



t
1

t immcu
EETIOD
US
us
US
us
•oasis
or CUES
2»3
2*3

10
met
a) lot git«n
b) lot giT«
c) lot si no
lot giro
lot sires
'ot givaa
SMI I cEBtiu iiroBBinoB i IETESXICS
1 1
1 t
i) <0,9 19/1*0 «1 | i) lorn ligclaa aad laacastar | Jekaao*. O.K.
b) -»•
1 «>fl* 1 Cuaia, D.I.
1 c) Iue»t«r rtaid«*ts. cotjwsita | Hos«afeM, J.I.
I ««npl« | t»7S
t I CTI-«00/1-7«-OI9, 235
1 CiltforilM* liTiig do»«ii4 fro* a I pp.
1  tk« kigfc I
I 4<>ert rwjlei of lue**t«r. »g« 1
1 gtonps: 1-1f. 17-34, 35 or mor« re. |
1 «OV «hit«, »0« aoa-ihlta t* lo> I
1 >•«•!«. 80* «klt«, 20* »oi-«hit« l» [
\ I«eist«r. |
1 |
1 inus: pinnras; ruium: tin; t
t iefOLKtiai KPOSOM: occopuiofit i
1 nxiEtS; ctiirotnt; itrrofsizs: i
1 HOOD; (IBHTS: SM.IEI; uii- raill; 1
1 muss: mscust ivttost Tissra; i
1 iirra: CORPIMTIR tniUTioiSt »s» i
1 JESSiT; CHIN: mm: UTOMTITI i
i - - - i
1 	 ! 	
<0.02 aaV9 1 lo* MaolM «nd Laacutn ro«ia«nt« 1 Jofcnson, g.i.
1 | Pt«TOJt, S.J.
1 callMntai* llrlaa dovnled Iroa a I tilled. J-B.
t ft««»«T In Ic« lag* In or in tk* kiafc I Caaaiia, O.K.
1 d«Mrt caglci of laactttcc. lg« | BoMafcU, J.B.
1 atoips: 1-16. 17-3». 35 at *oc« T*. 1 «*T«
1 tot chit*, *0f 90t-«kita la tos t Kl-600/1-76-019. 23S
1 Jn^«l««. to* vklt*, 20< aoB-vklto ia I pp.
1 laacastvc. |
1 »TRS; PLITHUB; PHUDIOB; 1EID; 1
1 ICPtUlTIOR HPOSIHIt; OCCOP1TIOIU. 1
1 IlliS IS; CllITOMIl: tVTOPSIB; 1
i ztooo: KIOKIS: spun; HIIJ; nun; i
1 tO«SS; !I9SCUS: 40IPOS! TISSOI: I
t iifEt; coipitinn miMTiois; n* t
1 JttSBT; C1I1E1: IIIIK; 10TOBOTITI |
1 1
t 1
*7 ppt f toa la?al«a r«aiil«>ta I joknsoa, P.I.
1 1 Prorost, ».J.
1 latopsUs, 1Z-7« rr old». | TUl«rr, j.».
t 1 C«a««n, D.r.
I HT»is; PIIIIIIB; PUIIVIOI: LBID: i goa*tf«u, J.B.
I Topnmoi EXPOSOIE; OCCO?ITID»M. i 117*
i Binars; curromi; IBTOPSIIS: i iM-«oo/i-7t-oi«, 235
1 HOOD; KiDBtis; SPIES*: nit: ttn»; i pp.
t loies; SOSCKS: taiposi tissast I
1 IDtP.; C01PIHT1TS tfllVtTIOfS; RV I
1 JHsn: ci»u: mites IOTOIOTITI i
i i
t ppt | lac la«al*> resldeats I Johasoa. D.I.
1 t Iftnst, i.j.
I Ittopsios. 12-7* rr olds. I llllwr. J.B.
1 1 caa»n, D.I.
1 fltlLS: PIITITOB; puikBiai; ttiv: I BosaafaU, J.B.
I lOPOHflOI IXPOSVIE; OCCnPITIOBJL I 1*76
i B im«; CU.IIOMII: amopstiss i Kp«-sao/i-7«-oi», 235
1 HOOP; KIBIIIS; SPIMI; Mil; milt; | pp.
I ines; nvscits: asipos: Tissue- i
i tun: coRpimxn mmiTiois; n« i
t JHSlt; CHItt; ft* IK; 13VMOTITE I
1 1
(Kit PIGE| . .
                                                                                                                                                                            N>
                                                                                                                                                                            .p-
                                                                                                                                                                            o

-------
falladi*!
7MO-05-J
ft
M •»«.«.  n 1555 C, SP J1S7 C, fp 1 •• Hg at 1»tt C.  10 » Eg at 2290 C
                                                                                     (COBTMBED)
nssoi
4339
LHfifl
aaWinj









wo










*3«1










*3«2
Oriaa

















iiposon BOOH



















































tinmen
•ETBOD
US










US










us










us

















BWBEB
OF C1SES
10










10










10










a| 203
b) S8

















I1IGE
lot glT*n










Mot girea









- —
lot gitaa










a) Bot glfea
b) 0.10-2.61 ag/1

















Mil
<3.3 ppb










<2.2 ppb





















a) <0.3 ag/1
bl 1.07 » or - 1.68
ag/1
















««ni i»o»»i<»
lea lagelea caatdcata

latopaim. 12-79 yc oils.

BFIILS; PHIIBOB; MtllDIOB; 1EU>;
PCPOHTIOI 1IPOSHBB: OCCDP1TIOHL
tazutfiS; ciiirtnni: IOTOPSIES:
P.1009; KIDIII3; SPMEl: Ball; null;
miss: mjsctis; iinposi TISSDI:
iiTij; coHPaunrr EniOHiois; IEV
JEBSET; Clllta; BtlHG; moBOTITE
loa lBg*l*a xaaldcata

lotopaias. 12-7» TT olds.

EIT1IS; PlaTIBDB; P1LHDIOS; LIU:
corniTTOi EjposDEB: occur ITIOI it.
« ins is-, cinpoBinj imotsizs;
BIOOD; nmns: SPIEEI; B»B: OEIIE;
UIGS; BOSCIB: 101 POSE TISSUE;
IIVEB; COKPltaTITC ETtLDITIOBS; IER
JtBSEI; CUata; BIBIB6; inoBOIITE
lea laaalva naideata

tntopalea, 12-79 TT olds.

enus; PI1TIBUH; PUIIIIDB; LBaD;
topoiiuoi txposrae; OCCOPITIOBU
aiziBDS; ctiiroBBia: ITTTOPSIES;
BIOOD; KIOIZTS; SP1ECT: Ball; UBIIE;
10IGSJ 10SC1ZS: 101 POSE TISSOE;
IITBI; COnallTITE CTHDaTIOBS; BIV
JIBSEI; Clllla; BIBI1S; 1DIOBOTITE
at los lagelaa aid Laa caster
c«aid«Bta
t) OccanatloBallT cxpOHd. Bighast
»«!»« i» stoiarocm »oiX«

CalifocBlaaa litiag dovnvlid £ loa a
fracnar la lea lag«l«s or IB the high
d»«rt reglaa of laacaster. iga
gtospa: 1-16, 17-3*. 35 01 aoi« 
-------
   t«ntaa«. 2-ntkyl-
   1C7-83-S
   C«-B1»
   n 86. 18. ft -153.47 C.  It  5«-«fl C. It  109 •• "« «t •* 1 C
IIS SOI
«3«3

MPOSIIS BOOTI
iBkalatioB

t»i. mot
HXTBOD
ec/BS

loam
or cuss
10

I DOS
0.5-5.1 19/1

Silt
2.5 » or - 1.6 sg/1

siiini IITOSUTIOI
is 2-awtkyl-2-p*ataBol (••tabollte)
Icrters In ska* factory IB Italy
BBiiE; BTDtocauois: inuoims;
mil: iiBDsniii ITBOSPHSBIS:
IlIDSniU BTGIBK; *XB POllUTIOl;
OCCDMTIOiai DXSI1SSS
nrzszBcx
P«rb«lliBl, 1.
P*T«BV I.
1980
Toileology and Ippliai
Phar.acology 53:229-229
        «. 2.2,*-trlMtkyl-
   ••O-M-1
   CI-Btl
   II 1U.2. tt 99.2 C.  TP *O.C •• •« at 21 C
IISSOI
«3««
Br«ath












Biposni toni














IMlItlCll
•moo
GO IS













IUHBIB
or CISES
S* (387
saBplra)












I1ISI
Bot gir«













Mil
0.60* Bg/1
G«OMtrie












GIKIlt IirolBITIOB
§«aior»a at 25 C aid 7*0 •• 89
29. ?t occurrence
loocc aai 
-------
CC-I1*
•i tf.n, BF 63.3 c, TF in mm 09 it lo.s c
IISSVI
•3*6
DrlM

IHOStB BORB
Dvraal

1*UITICII
•SWOB
«C/BS

I lOHEt
or cuss
10

I1I6E
a. 1-1.1 ig/i
.
Bill
0.5 » or - 0.» mq/l

enziii HFOI-UTIOI
is 3-*ctkTl-2-P«tamol (»talx>liU)
Oat* also «s Eolnatx is factory ail
1«rk*t» 1» aho* factor} in Italy
inn; nnocmais; nruoutis:
nui; iiogsniu IMOSFRIIS;
IKOSTtllt neiltti III POI1BTIOT;
CCCVFKIOIll IISIU13
-
•EFIUICI
F«rb«Ul*l. 1.
iteo
Toilcologj aid Ippllad
PharaacolojT 53:220-229
{•ctuelc
3JJ55-3J-I
11SS11
»3»7
imtk












TIJOSOSI 1ORI














uunicii
HRBOD
SC-BS













man
or cuts
5« C3*7
OMflW)












I1H> 1
1
1
lot gir«B













Sill
0.062 ig/1
G«oa«tcic












eilttll IlFOttlTICl
Mint*! «t 25 C »a 7*0 » Bp«r oM-sifn li*its
0.032 «l4 0.114 »V1

l«»ltfcT. 1«-3S Tt olfl, noABMUiig,
«rt»» blicki «J Caucasians.
C41cai]o. 11. lifillr coattoU»a
• ipvrtmtal oaoditlaai.
HIITB-. 1ICCBOLS: IUIIOIS; 1DV1TS;
tBLOHMIID ngBOCanOIS; T011TILI
tlSlKC COBFCraiS; 1ULTB B1IIBDS;
iiiumci; BEIIBOIISB: airiBoirris:
raFOiiTioi xiFosnE; ami istis
imsracB
KCOtOSXfMki. 8.X.
BTUMV. G.l.
O'Weill. fl.J.
1««
Joaraal -of Inalrtical
toiicoloqi 3:225-23*








 laatil alcatel  (» CD
 1-lwt»ol t« CI|
 7V»1-0
 C5-I12-0
 ii w.i. w -T* c. BF m.e c.  IF  i » B« at u.t c.  10 u
                                                            it
                                                                 .S c
1ISSHI t
1
I
*3«f
Bnatk











BXFOSIB KX1I
-













uuniciL
action
Be/us








"



BUBBEl
OF C15XS
8












Rim
•at 4«t«ct«a-fl.6D ag/kr











(HIT
«E»»
0.13 V9/1T











	
F1GE)
SI»»t TIFOtBlTIOl
Ce*Fon4 r«l«t«fl to aonal
i«t«bolisa. lo otk«r detain qlnt
CTT»9«aic saapliaq tccbnlgt*-

B««ltkT illltarr ail ciriliai
«iplore«». 0.3. lit Tare* Sckool of
l«rospae« a, a4«s 23-«7 jr. 3
saokera.
IfllEfBS; CBlCBIlltIO ITDtCCHBOIS;
CBtonn 03S1HC coBFoms:
tiioioBnzim; nuoBii! COBPODIDS;
tBtlTf: ItCCBOU; 1EIIS; 1BBIIS

nnanci
COBil*. J.P.
C»«pr B.J.
Mick, B.I.
1»75
irekiraa at
FBTironacnttl H«»ltk
30(2):2<0-2*5







-------
        alcohcl (8 CD
 1-Pentaaol (9 CI)
 7 IT* 1-0
 C5-B12-0
 n 88.1, IIP -79 C. It 137.8 C.  TP 1 •• Eg at 13.6 C.  10 •• Eg at *».9 C
                                                                                      (COEIXI9ED)
TISSUE
«3»»
Breath













ntosDBX BomB















IBalRICll
BET BOD
GOBS














BOB EBB
OF C1SES
5* (387
saaplas)













B1B6E
lot given














Bill
0.505 ng/1
Geometric













GBEBB1I, IiroBBlTIOE
teetered at 25 C aid 7«0 •• Eg
21.7* occurrence
IOMC and apper oae-Sigaa Halts
0.128 aid 1.99 mq/1

Btalthy, 18-35 yr old, nonsaokiag.
gttaa blacks aid ca«ea«tai».
Chicago, n. Kigiair controllaj
•ipcriMatal coalitions.
EHITfl; ItCCBOLS; IllIIOIS; IDD1TS;
enoiiMTte imociiMis; TOUTHS
CIS1IIC COBPCUIDS; BJilTB BltlRBS;
HBIL1TIOI: BIT1BOLISI; BEtlBOLITBS;
poroiiTioi ziposaiB: OBBIB u»s

SBFBBBICB
Krotossjaaki, B.K.
Braacao, G.B.
O'Mill, R.J.
H7»
Journal of inalftical
Toxicology 3:225-23*








1
Ihtaol
108-9S-2
CC-B6-0
II 9«.It. HI W.85 C,  BP 182 C.  T? 1 aa tg at »0.1 C
Tissue

• 350
OCiM








• 351
DtlM

















BIPOSOBE BOOH

D«raal









Inoestioa


















Jllimcil
HRBOD
9C









OC


















ins Bra
or cases
a) 15
b) *0








a) 39
b) 119

















BUSS

a) 1.0-5.0 aq/q
cr«atinin«
b) 5.2-13.2 ag/g
er«atiaia«






a) lot gira
b) lot gi*ea

















HUB | eilllll nrOBIATIOB
1
a) lot giTen | a) Coitrcls
b) lot giv«B 1 b) Vorkars espos«d to chloropheaols
1
1 Icrkats in herbicide laaufaetaring
I plaats.
1
| BfBBICIDES** UDVSTKZ&L PLANTS!
1 OCCOPlTIOItl B1ZH9S: PISTICID1S:
I fOPOHTIO» HPOSISE; BS1SU1BEEIT
| BITBODS; CBICBIIB OB61IIC COBPODBDS;
I tttlOlS; CIB1S1; 7BIBE
1
a) 11.97 » or - 11.60 I •) Besldaats lliinq 120-310 a fcoa
•9/1 | still site
b) 11.56 « or - 10.86 | b) Coatcola
KJ/I 1 B«asar«d « mo after Incident
1 >0.1 ag/1 fenad at least oaee in veil
1 «ater of study group
1
1 Bcsideats of East Tror, II. site of
I accldeatal rail car spill of 37,900
1 1, 197«.
1
1 Ciarrhea. aovth sores, dark vriae.
1 taraiig loath, reported by
1 significantly eore persons In study
1 groap than ia controls
1
I BISCOBSIl; OIXBZ: CCBPmTIK
1 BULUITIOIS; PBBBOLS; DBIHIB6 1»EB;
1 6BOn9 »T(B POlLtJTIOH; BETlBOinSS
BZIEIEBCB

Tan Koogaalen, p.B.
Klein, 1.1.
Draaaond. I.
19«0
International IrchiTOS
of Occapatioaal and
•5:5>«2



Baker, E.I.
landrigaa, P.J.
Bertozzi, p. I.
Field, P.B.
Pasteyns, B.J.
Skinner, B.C.
1978
Archives of
EBTiroaaeBtal Health
33 (2) : i9-«










-------
 fttmel,  c-ckJoro-  ft CD
 rkeiol. 3-ckloro-  (9 CI)
 tOf-U-0
C6-BS-C1-0
II 121.58. » J3.S C.  BP 21« C
IlSStff
• 152
tlaoi.
viols

















WWSflS 80 Ott



















ilUTTIClI
HETBOD
BMC


















inatra
Of CISSS
a) 35
b| U


















BliGE
*] 1-i« »«/g
»l 32 -U D4/g


















BUI
a) 19 ag/g
li| SI »»/g

















[
GIIIUL IIPOSU-IOI
«| loia Canal rullmt*. *« (1C)
FCiltlra
l| tolwtMca. 1st (2) positive
Huge *n
-------
  fhnol, p-ehloro- (8 ci)
  Iheaol. *-cbloro- t» ci)
  106-M-9
  C«-«5-Cl-0
  (I 12S.S6. H «3.2-«3.T C. SP 220 C
tissos
«33«
BlOOl.
• bole





















JIPOS01E BOOM
























imnxcii
RTBOD
HP 1C























IB8BSB
or CASES
a) 3«
b) 13






















flies
a) 1-90 a«/g
b) lot applicable






















mi
a) 29 «o/g
b) 2 a«/g






















GiiniL nroiRHioB
a) love Canal residents. 29* (10)
positive
b| Tolante«r>. 8* (1) positive
laiq* aal aeaa of positive aaaples.
Tilaes corcected for tecofety
Closelr satched, sisaltaneois control
sasples >ere not pcorlded foe
•aalTsis aloig «itk those ftoa the 36
IOT» caaal acea r«siA«ata sa«pl«d.
lacklnq seaalavfal control or
litecatace data relative to the
siwiflcance of the lo» reailaea
toned ia the field saaples analfxea.
ao tefialte conclusions can be dra»n
froa the resolts reported.
lesldeats of lev Tork. Controls,
esplovees of the SaTlroaseatal
frotection loeacy aad oaiTcraltj
atadeats. lorth Carolina.
II« TOIK; 10ITR CUOUM; BLOOD;
Bitsnzgsii mooDs; CHLOSIH OBGIIIC
CCIPOH»S: ciioioBtmns:
IIIaCHLOROBIREII; POITCEIOBWHID
fI«»ITLS: POPVtlTIOl RPOSOI8
mtSEICI
Bristol. O.I.
1960
IP1-600/1-80-03*. *0
pp.




















(heaol, p-altro- (• CI)
thesol, *-altro- (9 CI)
100-02-7
e«-»5-w-o3
M 139.11, HF 114.9-115.6 C, BP 279 C (decoap)
                                                                                                                                                                                          to
IXSSII
•3SS
Oriae



IIPOSOU BODTI




1IUTTICU
IZTBOD
SC



•OBBEB
OF C1SIS
12



I1IGE
0-0.5 ppa



8E1I
lot applicable



GEIIilt IIFOM1TIOI
fang* of seaas daring cotton spraying
caaaoa. RonthlT levels correlated
•ith orqaaorhosphate pesticide ase.
Cetton insect scovts, college-aoe,
•orkiag vithcat special protective
clctbiaq, bitalag » ith In 2 hr after
dallr «ork.
1C algns cr «Taptoa« of
orqaaophaspbate poiaoaiag.
levels iavereelr related to blood
ehcliaesterise activity.
IISnCIDSS; tniBOtlTSS; OIIIE;
atOlfS; OieitOPBOSfUTIS:
cccopHiomi guuis; tnnis
FIFEBEJCI
Barns, J.E.
Parker. B.fl.
1975
Archives of
Znviroaneatal
Contaaination and
Toxicology 3:3«*-351




-------
faeaol. peitacaloro-
tl-tt-S
C«-B-CIS-O
SI 26C.3S, H 190-191 C, B* 309-310 C (decaap), TO »0 an >« at  S11.2
TlSSffl

• 356
Blood,
HEM









•357
Hood,
aania














«35«
Blood,
vkole






















msiu lont

akalatlon











I>ka la tl 01









































aiaimcai
BSTHGD





























nic
























IOUZ8
OF C1SES
I 2
1 32
0 T1









•22
















a) 35
b| 12























illGE

) 1.68-1.15 ppa
) 0.116-1. OM ppa
) 0.015-0.055 ppa









a) 0.15-17.* ppa
b) 0.02-7.70 ppa
c) <0.01-S.«0 ppa
4) 0.02-7.20 ppa













a) 3-39 ag/«.
b) 3-15 ng/g






















(III]
mi

a) 1.72 ppa
b) lot given
e) lot given









a) 3.7» * or - 3.99
ppn
b) 1.72 * or - 2.02
ppn
cl 0.25 * or - 0.88
ppn
d) 0.32 » or - 1.25
ppn









a) 13 ng/g
b) 7 ng/g






















P.BB) •" "
61IEI11 IIFO1UTXOI

«) Girls, aqca 2 and * yr. Iron log
teae «itk 0. IK on Interior mod
nc face, 0.2f «
-------
   Chenel, pentaehloro-
   67-85-5
   ce-H-cis-o
   >« 266.35. HP 190-191  C.  BP 309-310 C (deconp) . It 40 H
                                                               at 211.2
                                                                                        (COITII32D)
IISSOE

4359
Urine












4360
Orine














EXPOSURE ROUT

Inhalation












Inhalation















IHLRICIL
BET HOD





























lUBEEB
or CISES
a) 11
b) 33
e) 1











422















I1*GZ

a) 2-87 ppb
b) 1-7 ppb
C) lot applicable











a) <0.01-7.80 ppn
b) <0.01-2.40 ppn
c) <0. 01-0. 40 ppn
d) <0. 01-1. 00 ppn












8E1I

a) Wot given
b) Wot given
c) 216 ppb











a) 0.95 * or - 1.93
ppn
b) 0.27 * or - 0.56
ppn
c) 0.01 » or - 0.05
PP»
d) 0.03 * or - 0.18
ppn








GtlZBil IITOBimOI

a) log hones residents
b) controls, untreated hoaes
c) 2 yr old girl fron log hose sith
0.11* on interior vood surface, 0.29
ng/cn n in air
logs dipped er sprayed with 5*
Fentachlorophenol
Kentucky residents of log bones bnilt
retneen 1975 and 1971 Controls.
10 pentachlorophenol-related health
croblens.
KHT0CKT: (DOLTS; CHILOREI: BLOOD
S1BOH; U3IJI; roiGICIDBS; FOFDLITIOI
HPOSORJ; PBE»OLS
a) Open-vat sood treatecs
b) Pressnre-tank rood treaters
c) Parners or pest control operators
d) Controls

Occspatlonally exposed subjects or
centrols in HI.

Increases in innatnre leucocytes and
rasophils, plasna cholinesterase.
alkaline phosphatase, gnita globnlin.
and nric acid. Decreases in serai
c«.
I111II: 1D01TS; BLOOD SERB"; OBI»H;
IIR1CRLOIOPBEIOL: BEILTB B1ZUDS;
IinaSTRIlt IIBOSPHEIES: IIBU1TIOI
SEFEREHCE

Belt!, 8. I., Ed.
1980
Chenicnl Regnlatioa
Reporter « (26): 823










Kleiner, B.s.
Vong, L.
Sato, 1.1.
Beicbert, B.L.
Korsak, R.J.
Rashad, H. H.
1980
archives of
Environnental
Contasination and
Toxicology 9:715-725





                                                                                                                                                                                            00
Pbatol, 2,«-Jichloro-
120-83-2
C€-B«-C1J-0
II 163.0, IP «S C, BP 209-210 C
TISSUE
1361
Blood,
•kale


















t
t
I
*
XXMSOtB SO DTK






















\
\
t
IMLniClL
RETWD
me





















1
t
«
M01IIR
or cisis
«l 35
b) 13





















t
_l 	
I1IGS
-
•) lot applicable
b) sot detected




















1
«
i
IE1I
•
a) 5 ng/g
b) lot detected





















\
\
GlIEBlt IiroRUTIOl
a) tove Canal residents, 3* (1)
pe«lti*e
b) Talnn teecs
lean of positive sanples. Talnes
corrected for recovery
Closely Mtchcd, sinaltaoeons control
saeples vere not provided for
analysis along vlth those fron tne 36
love Caaal area residents saspled.
tacking neaningfol control or
literature data relative to the
significance of the lo» residnes
fcand in the field sanples analyzed.
no definite conclasions can be drawn
Cron the resalts reported.
Issidents of lev Torr. Controls,
eiployees of the tnvlrouental
Protection agency and (Diversity
stadents, lorth Carolina.
Ill TOM: 1CRH CMtOUIt: BLOOD:
aitsoBmni IRHODS: CBLORIIE oBcinc
ccuponios; cau>BOBtit»ss;
nniCVlOVCBIRllt: KUTCBIOBHITID
1 fUBllTLS; TOlnUIIQl nCOSTIBB
1
lEfERHCE
Bristol, 0.*.
1980
EPJ-SOO/1-80-036, 40
pp.




















1 l

-------
Phenol. 2.»,r-tcichloro-
C6-S3-CU-0
Rl 1*7.5, IT 2S2 C.  It 1  •• 04 at 72 C
IISSBI
*3C2
Blood,
•hole






















EITCSVH tamt
























Hitmen
MTBOD
8PLC













•









IDS in
OF cms
a) 35
i) 13























UK2
a| 2-3 ng/g
t) lot detected























mi
a) 3 »g/g
b| lot detected





















1
1
efttm iBTOSBMiot
a| lore Canal residents, lit (t)
positive
b» Volvftteera
tange ago Be an of positive staples.
Values corrected tor recovery
CloselT Batched, simltaneons control
saaples me not provided for
aaalTsls alcng with tHoae Croc the 36
Io»« canal area cesUeats saapled.
lacklaq aeaninqfal control oz
literature data relative to the
slgalf tcance of tke lev resificei
fooBd In tie fleU sacples aoaljiea.
ae definite conclanioas can be dravn
Iron the reavlts reported.
l«>llents ot ••• tort. Controls,
cnployees of the InTicotaeotal
Protection locncr and naiTerslty
etgdents, lorth Carolina.
Ill JOtK; Km ClBOLUl; BLOOD;
HIlSriSMKlT BBTBOBS; CBLO1II1 OSG1HIC
CCIMBSBS; CBlOBOBEIIHESi
l»tCRIOICBtn»Z; POtTCBLOBUlTEB
tlPS!«LS; VCnUTIOI CTFOSDIE

IEPESIBCE
Bristol, D.I.
1980
IP»-600/1-80-036, BO
PP-





















Ihenl. 2,»,«-tric«l.oco-
86-06-2
C6-B3-C13-0
» 197.5, HP 68 C, BP 2M.5 C, TO 1 an Hq at T6.5 C
N>
-P-
VO

4363
Blood.












































AVtltllCAl
BETHOD
HPLC





















BUHBES
07 CUES
a) 35
b) 13





















luci
a) 2-« ng/g
t) lot detected




















(HIT
""
a) 3 no;/g
b) lot detected




















PiGE)
G"mt "»««««•
«) love Canal resldmts, «» (2)
positive
hi Tolonteers
Bange and nena of positive sanples.
values corrected for recovery
Closely natched, sianltaaeau control
sasilec *ere not provided for
analysis along with those Iron the 36
love Caaal area residents «a«ple«.
lacking neanlngfnl control at
literatnre dnta relative to the
significance of the lo> relidoes
fcond in the field sanples analyzed.
no definite conclnslons can be drain
fren the resells reported.
lesldents of lev lock, controls.
•itloyees of the Invironnental
Protection tgency aid eniversity
students, locth Carolina.
in tOBi: ions cuouBi; BLOOD;
flUSTJBMMT BIT BOBS; CHLOBI1B OBG»»IC
ccaioiiDS; CBIOBOBHZZIIS;
IIPHIITLS: POPHUTIOI EIPOSOIE

tEFIBEICE
Bristol, D.».
1980
1P1-SOO/1-80-036, ao
pp.





















-------
 fhaaol.  2.4 Fro* cord coatrol*
aaol/1 | «] Fro* infants with Titaaln
i) 1.76 » or - 0.31 1 tipplecent
aaol/1 1 (1 Froi infant controls
e) 2. 56 » or - 0.43 I tea* of 10 aa.
uol/1 |
f) 2.73 * or - 0.40 I 506 pregnant voau, 613 pregnant
aaol/1 1 centrals. Scotland.
j
1 SCOniBD; DinCT ntSDOB; IDOT.TS;
t lirins: BIOCI: OBBIHCIL COBB:
I ClICIUl; BTDWITCHOHC»LCIUBOIS;
1 Bisnsng; BIBSULS: nosnosas;
1 T41C? BLBBCB1S; TmnTB' PS OIST5j
I BIIZBlt BRIZOLISB; PIBGItlCT
1
|
a) 3. 51 « or - 0.07 f a| Kaasas Cltr. ts, harl-iater ar«a
•1/100 *1 | b) Kansas City. BO. soft-Hater area
b) 3. 66 * or - 0.04 |
•g/100 il | IS and to reslients satched for age
1 <>*aa agas 37 ana 37.7 rr), sex.
1 langtli of cesldeHe, larltal aad
1 aeonosic states, occapation, naalwr
I ef children, ssoklag habits, it, st.
1
1 I* hari-ratex araa. significant
1 licreaw in kyperteaslon, ICC
1 afenocsalitie*. and kTPecariceaia.
1
I iiisis; iisseni: anBits;
i ciiatoTiscnu DISSISSS:
i Btmnisxci; sroon snoa;
t c«aPUiTiTt triminois: cimitii:
I CUCIB«; cncBini: imtius:
I tieissiva; t«os?Bo»oos! FQMSSIOB;
I sctiasj me: Bioiccmnmoi:
1 ninais BIID
i
IIFESEICB


Cockbar*. F.
Belton, I.E.
P«rTl», I.J.
Giles, B.B.
Browa, J.I.
Turner, T.I.
VllkiBSOl, E.g.
Focfar, J.O.
Barrie, I.J.B.
BeKar. G.3.
Pocock. S,J.
1490
British Radical Jomrnal
28 1(6232): 11-14






Biareabaaa, B. t.
Fleischnan, I.I
9a*n, 3.
mold, J.
1»7S
lancet
H19H):100I-1016















OKI use)
                                                                                                                                                                                       10
                                                                                                                                                                                       01
                                                                                                                                                                                       o

-------
flcarkoraa
7723-ia-o
i
in J0.9737C, m M.I c. B* jga c, n 19 •• i« *t  12?  c
                                                                                   (COETItOED)
ussvt



a 367
Bale




















• 36*
Sidaar























4369
Llw






















XFOS01! ROOT*










































































luimcit
BET SOB
























n
























11























•01 US
OF C1SIS
























U 8

e» 12






















at »
W 9
c| 11





















11KS 1
t
























a) 2*5-39*0 *q/1
hi 373-300* «g/9
fl 215-3310 ao/j
a«t «t





















m) 606-3019 aq/9
b) (22-2315 09/9
c) 260-3600 og/5
•at «t



















(III
•Ell | eSBItll nrOIUTIOl
1
1
1
1 Bavta*. 2* npraawitatl**
I f ca— aaaliaia tractaaata aca
1 tabaUtad. Ika feasibility of a
1 Idllfltlc, ao-nak palter for hair
1 aaalyala l« eatlla«d aad sapportad.
1
1 mm: TSUI nmBts: Din:
1 IDSTBaLTa: BUSVBEIEK BET1ODS:
I eftus; FMTCTS', COBFIUTITC
1 iiiioiTioBS: uonn*; IBTIBOBI;
1 ISSEBIC; Blind; nOBTBE; C1MIOH;
i cuciuB: cnenBi: cBionoi; COBIH;
l ccppM; eiiina: esBiiinoB: COLD:
l lemiu 1101 j LunuTOBj mo;
1 B16BESIII: B1M1ISSE: SEECOBT;
\ tctrmDinB: ncin: THostBoiQS;
1 {CTJ3SIW: 10BIDIOB: SBXinOB;
1 SIIICOB; SILTEK: SODIBB; STBCWTMB;
1 sotroi: ti»: TTTHIBB; TOIGSTIII
1 TIIC; HBCOBHTI
1
1
a) 829 »q/g 1 at Coatcola
b) 1157 nj/f | b) Berkac  I
e) 12 £9 ag/g 1 c» torkat qreap n
•«t «t |
leiliu | caoaasai Mflaery aid saaltac
1 aotkaca, aq«a 5S-76 yr, crpoaad to
1 kaa*r aatal« 1-3 4aea4«a. Tla*
1 batavam tatitmaat a»4 tactk 0-1. S }t
I la icoap I aad 2-19 re, Itott II.
I ccatrol*, a<)«» «3-72 yr, ako U«l SO
1 ta fcoa tb« factory. s*ad«>.
1
1 SflOBB; Claims; HDinS; llTBBi
l Hies; coBfiiHiTE snmTiois:
t ntasTBiii H6II11: msmcBim
1 BIT BODS; lITlBOtT: IBStllC; CIDBIIB:
1 ctsm: CBKISIIJB; coBitt; COFIE*;
1 GCIO: IIOC IlRItBOB: HID;
1 BIB61IESE; BRCOIT; BOtlBIlBITS:
1 ciamnias; IOBIDIOB: SCIBDIDB:
1 SIIIBTVl: SIITEB: TIB; TOISSTEB;
i 1ITC: BSalTB BalllBS: IBDVSmn
1 (iins: SBiiTfflj; Tsuinivi
1
1
a) 1876 «g/g I a) Coatcola
b) »10 «j/9 1 B) Mtkac group I
e) 1S2« ag/9 t c) lortar qtoap n
Bat «t |
Badlaaa | cacaaaal raf laacr aaA aaaltac
1 aotk«ca. iqaa 55- 76 yt, axpoMl to
1 kaarr avtala 1-3 4aea9a«. Tlaa
I t«tM«a ratlraaaat »4 Oaatk 0-1.5 fc
1 1m group I aid 2-19 yr. groap It.
1 Ccatrols. «g«a *3-72 yr, *ko Unl SO
1 tt {TOB tka factorr. Saaflaa.
i stiBE*; cioMMS; Kirans: imi;
1 10BSS; COBP111TITE XT1101TIOBS;
1 IIOOSTEI11 ilOIIBE; VSlSOBEinT
1 B1TSODSJ iniBOtlj HSniCi ClDIKtB;
l CISIHB: cRBoranc coani: corpus
1 SOLO: HOB; 11BTB1BOB; tMD:
1 ii»ciwst: BiictjiTs MtTBDinm:
1 (lOSfBosvs: EOTIDIOB: ackisira;
1 siiifin: snrts; in: IOBSSIEB;
1 tlBC! BEtLTB BU1SOS: IfDOStllU
1 fllBTS; 3BHTEBSI TEUVIIOB
1
C f>61)
BEFBBEICE



Cbittlcboroagh. a.
980
Seianoa of tk« Total
BTlroBieat 14:53-75


















Brnn«, V.
Bordbaro.« Q.
feat«c« V.Q.
1990
sci«*ca of the total
E»lrt>Ba*Bt 16:13-35



















Broaa. D.
Bordbacq. G.
Faster, ?.c.
1990
Selaaoa of the Total
Eavlnuatt 16:13-35


















                                                                                                                                                                                      N)
                                                                                                                                                                                      tn

-------
  Ikospkoras
  1723-1»-0
  t
  tt« 30.9737C, IP M.I C, BP  280 C,  vp 10 » Ig at 127 C
                                                                                        (COBtllTOD}
TISSOS

«370
Inng




















*371
Brine









1
EIPOSOIS BOUT:























lagestion











» MI men.
BETHOD
11




















.
Chen











BOBBES
OF CASES
a) 8
b) 9
0 11



















10











BIKE

a) 38»-2«21 ag/g
fe) 67«-3516 ng/g
c) 1«(-98«* ag/g
Wet rt


















lot given










I
mi

a) 777 ag/g
b> 898 ug/g
c) 799 og/g
Ret vt
ledians

















0.69 » or - 0.1*
g/day










etIEUl IIPOSEITIOB

a) controls
b| torkec gronp I
c) Vorker grovp XI

Cecensel refinery and sselter
lorkera, ages 55-76 yr, exposed to
keavy aetals 1-3 decades. Tine
retveen retirenent and death 0-1.5 yr
in gronp I and 2-19 yr, group II.
Controls. ag«s *3-72 yr. vho lived SO
ka fron tke factory. Sveden.
SIBDBH: ciDifEBS: Kioisys; IITES;
IBBSSs COBPiBaTITB mLDlTXOIS;
IIBOSTSI11 BTGIEBE: lOiSOBBBDIT
BETioDS; inxniy; IBSSBXC: CIDMIBH;
CIStffB; CBBOBIDB; COEUT; COPPE1;
(OLD; IIOB; ItBTMBim; IE1D;
BIBGIIESB; BBSCOBT: BOLIBDEBHB;
fK)SPttO«9S: 61TBIDHJB: SCIBOXOB:
SfLEIlng; SIIfH; TIB; TDBGSTCT:
TIIC; BUITB B1Z1BOS; IIDOSTBIll
Pit ITS; SiBLTEBSi TEUnXDB
less after daily intake of 1.3* * or
- 0.28 g. Data fron *7 7-day
experinental periods.
University stadents and enployees, a
avrse and a teacker. Balliparovs.
ages 19-29 yr.
Fkospkoras talance slightly positive.
reflecting adeqaate intake.
IHEESSE*: OBiiE: iioi: ciiciim:
ilCIESIIg; RIIBBILS; PBOSPHOBdS;
CIETS; IXIZBlt BITIBCLISB; PBESI1ICT I
1
EERBNCE

Brane. 9.
Bordberg, 6.
Vester, P.O.
1980
science of the Total
Environsent 16:13-35
















(she, J.E.
Sckotteld, r.l.
Gran. 8.8.
tnecican Journal of
Clinical Intrition
32:286-291




1
	 1
                                                                                                                                                                                           K>
                                                                                                                                                                                           <_n
                                                                                                                                                                                           N3
Iktkalie acid, bla(2-«tkrlbezrlt ester  (8 CI)
1.2-Benzenedicarboxrlic acid. bla(2-ethrlkezTl) ester  (9 CE)
117-81-7
C2*-B3B-O*
I« 390.5*
TISSOS
• 372
Idlpose
«373
Spleen
IXPOSITBE BOOTE


1I1LTTIC11
IETROO

t
1
BOUSES
OF C1SES


BalG!


BE1I


SEIEU1 IIPOSUTIOI
Beview of effects oa biological
systess with enpkasis on safety
CTalnation aad levels encountered in
aedical devices
iriwsi TTSSOE: spun; BSTII«;
IBTHLIC iciDS: reriBouss;
nitBOLIIES
tevie* of effects on biological
ststens vltk eapkasls on safety
evaluation anfl levels encoaatered in
aedical devices
ttltOSE TISSUE; SPLEtl; BEVIZV;
tmuic tens; BSTIBOLISH:
mnOLTtis
EETEBEBCZ
Thoaas. J.I.
Darby, T.O.
Kallin, B.F.
Garvin, P.J.
Hartis, L.
1978
Toxicology and Ipplied
Pkarnacology *S: 1-27
Tkonas, J.i.
Darby. T.D.
•allin. B.r.
Garvin. P.J.
Hart Is, I.
1978
toxicology and Ipplied
Pkarnacology «S:1-27

-------
Ilatiaaa
74*0-0«-«
Pt
It* 195. Of, IP 1773.5 C. IP 3827 C.  TP  1 u  H« at  2600 C, 10 as 89 »t 29*0 C
iissirs
»37t
HlpOM
»37S
BlOOl
«376
Bair
•377
Kidner
BXPOSRSE BOITE




aflinXCaL
H ETHOS
US
us
us
us
IVRBEt
or CISES
0
83
.
283
10
suet
lot aiTsa
lot given
) lot git«n
] lot glvaa
«J lot giian
lot glraa
lot glToa
nn i SBiiui iiroBuraoi i IEFBBEICE
1 i
i i
I I
1 <1.3 ppb | a) los lagalaa r«sld«a.ts | Jotaaoi, D.B.
I ». ? ppb | ft) Occapatleaallf «xpottd | PreToBt. l.J.
( | Hilary, J.B.
I latopalas, los Itgalas, 12-74 TI olds I Caaau. D.E.
| tit » 51 yt oU *aok«r »ho »U«8 uA I BoMif«U. J.B.
I fioc«ss*d ft. Pi it Ottirio. | H7S
1 | IP1-&00/1-76-019, 235
| tZTlLS; niTIIDI; PUUIim; t!U»J | pp.
t (QPOltnO* IHOSV1B; OCC1»lTIOItt |
1 gillBIS; CIUPOSIH; IDTOPSItS; |
1 tlOOI; XI tills : SPLBZI; Bill; OSJiE; |
1 ivies; mscus: impost TISSVB: i
I inra; comiuTiTB miiatiois; IB* i
1 J1BS1T; Cllltl; milSl atROBOTITB |
i i
I 1
a) <3.1 «g/100 mi [ a) los ia««l«s aad laacastn ( Johiwm, D.J.
b) 0.0*9 aq/lOO ml I taai«««t«. laolTlaaal  inn; CO«P»I»THI ininiuoas: m i
I JtBSBTi CIIIC1: iniM; mOHOTITI |
i i
I i
<0.05 a?/g | lot lioalcs lad Lancaster EMlOots I Johana, B.S.
1 I vc«ost. t.J.
1 Callforalaaa llTiaq ao«n»i»4 froa a 1 TUlar?, J.B.
1 (r«*»ay 1> los iigclas or 1* tka klot 1 Caaaaa, O.e.
1 ats-art roctea of Lancalter. lq* I BosaafeU, J.e.
1 gtoaps; 1-61. 17-3*. 35 or aot« TC> 1 1*7i
1 «0t «alt«. »W loa-ihlt« ia las | BP1-«00/1-7C-019. 235
t laaalas. 80* vtita. JO'S aoa-«1iit« U I pp.
1 lageaator. I
1 1
1 tit us: IIIIHOB; riiiiMOB; IBID; r
1 (OPIUTtOI tXPOSVKZ: OCCHTMIO111 |
1 UZaBES; CILirotlll; iDTOPSItS; |
1 BtOOD; CIDKIS; SfllH; H1IBJ VHIB: 1
| IOI6S; SDSCIES; 1DIP03! TISSUE: I
| IT1B1; COBTlMTln mWitlOIS; IB1 t
I iiisBT; emu; inriia; HITOBOTITE t
i t
<2.« ppb | tea *mo*laa milnta | jahasoa, D.B.
1 1 Frawst. t.J.
I autopsies, 12-7» yr olas. 1 TiH«ry, J.B.
1 1 caaaan, D.B.
1 tnus: TimnB: PUIIIIOB; LBUI i nsoafeid, J.B.
| iOSOllTIOI tlPOSBK; OCCOPKIOail 1 1»7«
1 Bins is: cuirosiii; IVTOPSIBS; i tM-«oo/i-7«-o». 23$
t HOOD: titiiTS; snEBii BIIB: OBIIB: i pp.
1 iwesj aasciis; IDIPOSE nssoz; i
| tltt»; COHPalltlfB BntVltlOU; IBB 1
1 jt»BT: ciini; BniK; IOTOOOTITI i
i i
tint MGE) ' 	

-------
ruttm
7WO-W-*
Ft
»M 1*5.09,  I*  1773.5 C. B* 3827 C. T» 1 «• »9 «t 2COO C. 10 •• 84 at 24*0 C
                                                                                   tcorcmmi
1
1
1
1
ttsssi
«J7t
tl«r
«37»
t««
«3«0
B
•Ot fiTU
BMB i sBBitti imiiraoB I immcs 	 '
i i
<0.2« ppb | Io» 1>9*1«* cai4mti | Jaks«o>, ».«.
1 1 *r«TO»t. S.J.
I lltapiiM. 12-19 it old«. | TillMf. J.B.
1 1 Camu, 9.B.
I sntis; KJimi: »iu»m: t«»; t lowitcu, i.g.
1 rerramoi nrosni; OCCPPITIOMI j i»7«
I IIM1C3I CIIIFOIIU; kITOFSIBSt > t?t-«00/1-7«-019, 235
1 HOOD! KIBMIS; SniH; Bill; UHII; | pp.
1 idlest nsctts; UIKSI nssoi; t
I inn; cotPtuTm inumois; tvi i
I jetsrr; cuict; BIBIMI totontm i
*) <1.3 ppb | •) tos Ii9«l«i t««13«ta | Jokiwom. B.S.
») 3.T ppb | t| Oec«p.tlo««llr •rpaOT4 | tmemt, t.J.
1 1 Till try, J.B.
I litop«l««. to* l««*ln. 12-7» yr alts I Own, ».».
I »a • 52 Tt eU rto *ta«« ud I Boamtcld, J.B.
1 fioeMMt Ft, Fd i» Oxterie. 1 im
! mo., »«mi, F.UOI.B, lun ! »f-*°fl/1-7<-ow- M5
t toinmoi nFosoii! occmiTioiti i
I milts: cuiroinii inoFsiis; i
1 BIOODJ nntis; spttM: BIII: unrs; t
\ tnss: iffsctcs: IDIFOSE Tissoi; i
I Hint coRpmnrs zntnnois: 13* i
I JHSBT; ciMct; lima; anoaotm i
i i
• i 	 	 ,' 	 	
«) <».» ppb | *> los 1>?«1<« n«t4«t> | Jok.wi. D.B.
b> 2S.O ppb 1 t) Oeeapatloully •zpowd I Pr.TMt, J.J.
1 I Till«j. J.B.
1 »ltop»l«8, m li^ilm, 12-79 ft olds I cum. B.E.
t »d * 22 TT old nokir 
-------
»t
    m.«9, 0 1773. S c.  BP  3i27 C,  TP  1 M  Rg «t 2600 C,  10 •• Sg at 29*0 C
                                                                                     (coniivio)
nssn
nn
Vrln

















mosnu BOBtt



















iiumcii
RBTBOD
us


















mm
at cms
a) 213
b) <

















•MSB
a) tot glim
b) 0.23-2.58 ig/1

















nu
a) <0.6 «oyi
b) LOT 09/1

















6EIH1I I1TOI1UTIOI
a) lo« lag«l«a aid la»ea«t«r
z**id«Bts
11 Oce«patlo»llT «xpowd

CallteTBiaac li.Ti.Kj domviad from a
fr*««T !• los 1*9«1« or ii th« higk
ItMrt c*qlo> of lamca«t«c. kg*
qrotp*: 1-K, 17- 3», 35 ot mor« jr.
COf «kit«. *o< «m-«Ut* li lot
U4«l«s. ««« *Ut«, 20« UB-vhit* IB
I>ica«t«c. !•« J*C<«T r«fi»«rr
•ottir*
JITU3; H-ltlWH; fltUDIDl: LIU;
to?nmoi nposmti occnettioiti
•nuts: ciinoint; IOTOPSIIS;
HOOD: ximiTS: snt»; BUI: ami:
i»«st nscus: igitosi nssns;
inn: comtuTin imautaist HI
JIISIT; CtllDl: 8II1BS; IDTOIOTITS
tmisicx
Johaioi, 0.1.
PrVTOBt, B.J.
Tlll«cr> J-3.
Caiun. 9.1.
«OMBt*U. J.B.
1«7«
IPl-«00/1-7«-Ot9, 23S
PP-











PlubaM. cklorotrirtkyl-
1067-M-T
e«-«is-ci-Pb
•* 324.9
1ISSDI
«3*3
idr*Bal
glaaft
»3»«
•loot
•3«S
IralB
txposoiB tons



1ULT1ICM.
BRBOD



«8BES
OF CiSES



met
-


HIM



etmii nroiamoi
>6»: nsBis: POOD
cotMHiuTioii rons: usoLin;
enmc tmcrs; mvsniii
icciDtns: imitRai: HBBH tstis
**Ti«. ToiicaklMtlo aad to lie
•ftcctB of ocgaaolBad coapoaBdv*
eirtBat occiiitloul and
•BTlcoaBoBtal (ipoiit* data.
•IITtO StlTIS; SVBOPt; IEW CietRIC
cctKmiBS; imoBotm; in PcitmoB;
<«iciiosti: ftsBis; FOOD
com«m?ioi; runs; sisoini;
entile iincn; WDUSTSIII
iccieiirsi iHuinov; UIBII uiu
Kria*. ToxleoklBotles aad toilc
•tfocti of otqaaolcad eoapoaads,
e«tr*>t ocetfatloaal aid
•artragMirtal KBOBBC* d*ta.
eiltlt STITtS: EIBOPI; USD CB61RC
coiFOTiDS; amoRoiiTB: in PCIIOTIOB;
ciiciKaii; nsBis; TOOD
COITlRIIHIOfi TOESS; 51SO1IIB:
cnrrrc CPTICTS: noDsnui
icetgiRS; tmunois isti* IBEIS
t
tirBIEICI
GzandjaaBi p.
IlclMl, T.
1979
Kealda* Barivwa
22S97-1M
ecaaljoan. f.
IlslMi, I.
1979
ItBSldW S«ll«»S
22:97-1**
GzaBdfcaa. p.
Uelaea, T.
197»
s«si.4m BBTlwis
22:97-1*1
(HIT pun
                                                                                                                                                                                         Ul
                                                                                                                                                                                         (Jl

-------
1«7-1*-7
C6-B15-C1-M
«I 329.1
                                                                               Ccomvtm)
TISSUE
«3«6
B««rt
»387
«3I8

4390
•aacccas
«391
I
EIPOSBBE BOUT






immcii.
IITBOP






rrasn
or c»sss






BUGS






m> i 6MI1U xmtiiTxei i EEHSEBCE
i f
i l
1 Mvlo*. ToxicokiMtica- and toxic 1 GraadlaaB. P.
1 «f facts of orgaaoload coapoonds, | Bi«lMB, T.
1 cort«Bt occvcatioaal aad I 1979
1 €BTirOBB«Btal *xponr« data. t B«sU«« B*T!««B
1 1 22S97-1U
I IBI1IO ST1TH; ITOOPB; LI1B CBGMIC t
1 CCBPOVflS: IROBOTIVE: III PCLIKXOB; |
l CHCIBOSH: USB**; torn i
| CCRlBIBinOB; T«BXS; 61SOIIBE: 1
l SIBRIC tiptcxs; IIODSTBIU i
l icciDEBTS: iwiiMiati trsBtf IBHS i
i i
1 i
1 Bavie*. Toxieokiaatiea and toxic t 6raadj«u. P.
1 affects of orgtooUad coapoaala. | litlatc, t.
1 cgtrut ocncatioaal and | 1979
1 " 1 22:97- 1M
1 oimg sTiTis; sraopt; tew nsanc i
1 COBPOmSS; iniOSOTITE: III PCIIRIOB; I
t CISCIBOBIU fMIIS: fOOD |
1 COBIIBIB»IIO«: VmtS; S1SO1IIB; I
I eiBtric crrscTS; mosisiu i
l iccxpnrs: iraitiTxai: nati IBUS i
i i
1 l«»ie». Toxieoklactle* aad toxic 1 CrudTaaa, P.
1 •tf«eta of orouolMd oovpooads. | Bialaam, T.
1 cirtmt eccafatioaal aad I 1979
1 *atiroaa«t*I •xposace data. | P«»ia«« g«ri«r*
( 1 22:97-1*8
1 BBTTXD 1T1IIS; EOBOPI; »AD CJSMIC I
1 CC9POOVBS; lUTOHOTITB: 111 POllVTIOB: |
1 CIBCIBDSK; flSBES; FOOD |
1 CCBTIHMTIOB; THUS; eiSOIIBZ; |
1 CIBRIC SriBCTS: IBODSniU I
1 iccnrars: IBBIUTIOB; TOBIB IBIIS i
i i
i i
I !•*!•*. Toxicokiaetica aad toxic I Graadjaaa, P.
1 aifacta of otvaaolmd ooapoaads. I Bielaaa. t.
1 citnat cceicatloaal aad 1 1979
1 »«Tlro»B«0tal oxposat* data. I Pesidne Sawieas
1 t 22397-1W
| VBXRI SIIIIS: EOBOPB: 1113 CIGIBIC I
1 ccBpcrais; ittoRcnrs: ax* rcivmoi; »
l CHCiiosm: IXSBES; POOD i
l coBTiixiiTiOB: raiss: eisoim; i
1 CIBRIC inters-. IBBOSTIIU i
l iccxonrs; IIBIUTIO»: OBBM IBIIS i
i i
1 l
I !€*!•>. toxicoklMtica aad toxic I Grand 1«aa, p.
1 *ff«ets of onjaBol«ad coaponada, I Heist t, T.
1 corrent cecacationtl »d I 1979
1 tiTlroBMBtal •xpomca data. I Besldaa B«ris»a
1 1 22:97-1*8
1 OBITED suns.- tmort; IEU cseinc i
l ccBpcgBos: amoBtmtx; us paimioB: i
| CISCIBOSIB; TISBIS: POOD |
I ccBTiiiuTioi: rnns: eisaxiR; i
1 sunic srrecrs; IIBDSTSUI i
1 iccntRS: iBBtunai; OBBH IB us i
i i
1 l "
i ««»ie». Toxlcoklactics aad toxic 1 eraadjoaa, P.
I affacts ot oigaaolaad coapoaats. t BlelMa. 1.
t c«rr«t eccatational aad I 1979
t «niroBa«Btal vxposnr* data. 1 Casidne S«rie»s
t 1 22:97- 1»»
1 tiBTno sTiits; IBBOPE: LIID CXCIBXC i
1 CCBfOVBOS; IVTOBOIXTt; KB PC1HJTIOB: |
t OBCIBOSIB: IISBE5; MO9 I
I ccBTMiiiaTiOB: rnns; cisotnt: i
l eiiRic inccis: IIBUSTSIII i
| ICCIfiinS; 11S11ATIOB; OTBH 1511S |
' - t

-------
          eklo»trli«tkrl-
•1 287.77
tissm
•392
Drln









BIMSDtl lOtRC











itiimcii
BETROD











iraitt
OF C1SSS











UMH











BSlB
.










-
eniui xtroBBiTiai
(«!•«. 1axicoki«*tie* »»4 toxic
tlfccts of orgaaotead coipouda.
decent oeemcatlaul *ml
(ETicoiMitil eiponr* data.

tlTTZD 3TITI5; 101OK; IZ1D CBOHIC
coBEOtmos: IBTOHOTITB; in raionoi:
CIKttOGtl; TI58K; MOD
ccntBiiMioi; rons; cisaini:
eiimc ti tiers; iiovmiu.
ICCIDMIS; IIBIIITIOI; 5BB»Ji 1BU3
BITHEIC!
Ciaaajui, t.
li«lMD, 1.
1»7»
K»llie E«tl«»»
22s 9 7- 1*S






        , t«tr>«tkrl-
78-00-2
CI-BIO-Pb
g« 3Z3. »5. 4? 125-150 c, BP approi 200 C, TF 1 m Bg at 3«.» C
tiasai
•»3
11004
139*
Btla»
nrasmc EOTTI


UllTTIClI.
BITIOO


•TIBBn 1
or cisss


SU61


mil


Sttllll 1IFOIB1T10» |
1
1
•cftn. ToxloaklMtles aad toxic
•fleets of orgaaolaal cocponds.
cictvat occafatiooal and
««Tlroi*««t*l •xposat* data.
0»I1« SUTtS; fOton; UU CB6MIC
ccipotuss; unoaoTUB: in PCLIOTXOI;
CIBCIIOS1I; flSHBSS IQQD
coiT»ii»»Tioi; rums; GISOIIBX;
EIItTIC XIItCTS: IIDOSTBI11
ICCIDIMS; nauiTioi: nsaii tiiu
f«vi«v. Toxicokiaetics and toxic
•tCcets of ocfaaolvad coaiiott»S«.
cocreot occafatioaal a»d
• evicoaMatal eipoavre data.
DIIIID suns: ztnoPE; iziv CRGIIIC
COBfOIJlDS; imoBOTITB; UK PCU.DTIOH:
ciBcnosH: lisa is; FOOD
cciriBi!HTio»: tans; eisotnx:
GIIITIC tillers: noosmii
1CCIBMTS: IIBltlTIOI; VBBtl 11US
tXTEBZICB
CC&aijc*D, f .
nielMB. T.
1»7»
gcsidie S«Tl«a
22:97-U8
Grand jeaa, T.
HUlMIL, 1.
H7»
Kealdae B«rl»s
2S:»7-1«8
                                                                                                                                                                                         Ln

-------
Tolybronlnated biphenyls  (Bo postings  i» CBiniR).
TISSBt



»39S
Blood
























«39«
Blood,
plan*



















4397
ood.
sens

























ETPOSB1E WOT

















































gestlon



























imrticit
MTBOD


8C/BS
























6C/BS




















6C-EC



























BOB an i sites
OF C1S3S |
1

21 I a) 1.1-57.3 tg/mg prot«
I b) 0.03-0. CT »g/sg
I protein
1 c) 224-282 ng/eg prot«i
1 4) lot detected

I
I

I

I
1
1

1

•
1
1
1
1
1
1
t
1
1
1
21 | a) 0.13-10.2 ng/ng
1 protein
1 b) Wot detected
1
1
1
1
1

1

1
1
1
1

1

1
|
1
1
290 I a) lot given
1 b) lot given
1 c) lot given
1 d) lot given
I e) lot given
1 f) lot given
1 g) lot given
1 h) lot give*
1
1
1
1
1
1
1

1
1
1
1
1
1
I
|
1
1
1
»
nil i ciniu IIFOBIITXOI
I

t
a) 23.75 ng/ng 1 a) leukocytes. » exposed chenical
protein 1 icrkers
b) 0.35 ng/ng protein I k) Brythrocytes. » expos*! cheeical
c) 253 ng/ng protein | workers
d) lot detected I c) Beta-lipofroteln fractioa, 2
j «xpoeed ckeeieal workers
1 d) Leukocytes or erythrocytes, W
| csbjeets. including ezpoMd dairy
1 farn residents and controls.
1
1 Bichigaa ckenical workers and dairy
j fare residents exposed to Firenaster
j IF-C. Controls, dairy far* residents
j ie liseonsin.
1
I Stimulation dysfnnetioB of
j lynphocyt*sl tested *ith
| rkytohenagglitiBin and pokeeeed
I nitogen, especially in the * exposed
1 ekeiieal verkers.
1
| ICITBJO1II1TID BIPISITLS;
1 IlTtnOCTTIS; BLOOD niSHl;
I IIOKOCTTIS; HCHieil; IIDOSTtTIL
| IlirtS; IIDDSTBI11 ICTOSPHEBISi
| IIDCSTKI11 DISE1SSS: IISCOISII
I
1
a) S. 1* ng/ng protein | a) 4 exposed ckenical workers
b) lot detected I e) 18 sab-fects. laclwdiag exposed
I dairy fare residents and controls
1
I Blckigan cheiical workers aad dairy
1 farn residents exposed to rirenaster
1 EP-6. Coatrcls* dairy fars residents
I In llceonsln.
1
I Stinlatlon dysfnnctlon of
I lyapnocytes, tested with
j piytoheingglatinln and pokeweed
j eitogen. especially in the * exposed
1 ekenical workers.
1
| fClTBiOIIMTID BIPB1IT1S:
| UTTnoCTTcS; B100B FLlSBt;
| IIDROCTTIS: mCHIGll; IIDOSTIIIL
1 Fiins; iiDosrstai ITBOSPBEIFS;
| IICOSTBIll DISB1S1S; WISCOISIW
1
1
4.23 ppb I •! 1*» sales
2.72 ppb I t) 1(3 fenales
2.75 ppb | c) 0-« yr of age, 33 soblects
7.08 ppb 1 d) 5-8 yr old sales. »0 snblects
a. 32 ppb | e) 5-8 yr old fenales, 37 sablects
3. 18 ppb I f) 9-12 yr cf age, 81 subjects
3.»5 ppb f g) 13-16 yr old nales, 59 subjects
1.87 ppb t h) 13-16 yr old feeales, «3 subjects
1
1 lleklgan children living on
1 Pie-contaninited fans or children
1 censoeiag neat or nilk froe these
t fares.
1
1 lo significant association of
1 atnoraallties and seres PBB levels.
1 Significant negative correlation
1 tetween Hunter of reported synptons
1 aid oer«n PBI.
1
I FCITItCHIKlTlD IIPHBniS; B1OOD
1 si80«: CHn»in: ncwietii: nscoisii;
| TCtD COB1»1IHIOB; 1IIH11
1 tOPDHTIOlS; TUBS; COBFllVIIVB
| miUlltOIS; BtOIIIB 01111 1C
| CCBIO019S: Sit; X6B: BlaltB BIX1B9S;
I tins
i
UriBEICB



BobOI, J.
Snznkl, B.X.
Bexesi, J.E.
Bolland, J.F.
1980
Journal of
Bnvironnental Pathology
and Toxicology
3:3«3-37i



















Boboz. J.
Suzuki. B.K.
Bekesl. J.6.
Holland, J.F.
1980
Journal of
Eavlroueatal Pathology
and Toxicology
3:3*3-378













Barr, R., Jr.
1980
Environnental Se search
21:255-27*
























                                                                                                                                                                                     N3
                                                                                                                                                                                     Ln
                                                                                                                                                                                     00

-------
 relrferoalaatad
                        l»o pe*ti»9» la
                                                                                (cotnimo)
IHSM
•3M
•Ilk









•HOSm MDTC











1M1TTIC1I
IJTBOD











mm
or CISBS











UKI











m»











CEIfUt IIFOBBITIOI
_
l«i*v of Mr«aaat«r coattalntioB ef
cattl* e««d la Bickiga» ul
T«eon«4*tiau for anslag lotlwra

jipii: ignis; Hurts; ssn
Bisiisis: ntxr imn:
fOlinOinillD BIPHMTIS:
tCIYCHlOMIllIB BIPBWTLS:
iioiccomiiio*; mi iiriisins;
iocs coniuuTioi; rooos; LICTITIOI;
pofjiiTioi inosvn
unmet
Rilltr, I.«.
Tinb«rg, 1.
1ST7
Jonn*l at Pediatrics
*0 (3) -.510-512





.
tetwslM
1»
I
                  c.
                                   100 M sg »t wo c
TISSVZ

•3*9
Hood.
aartta
















a»09
Iraata









aalr








nosou SOBTE




















Inhalatlaa



















IHLTTICIJ.
BBl'BOD
US


















mi










us








•BSSSS
or cisis
«1 2«0
b) 260

















1










a) 31
b) 22








11TCS

a) lot gl»«»
b) lot gl»««
















-
lot gl*aa










a) lot alvaa
b) lot gl*an








mi

a) a. 11 » or - 0.05
M^/l
bl *.32 + ot - 0.03
aaq/1















10S.O ng










a) 1359 ppa
b) 12W ppa








GEIIttl mOSIlTXOI

at taaaa* city, IS. k*rd-aat«r am
b) Kaasaa City, to', aoft-vatcr ana

IS and HO raaldaata aatch«d for aq«
laeaa aq«a 37 and 37.7 re) . aex.
laaqtk of caaidaaca. aarltal ana
«eoaoalc atatu. occapatlon, aaabar
of eklldcaa, aaoklag kablta, it, »t.
la bard vatac araa, algaitlcaat
leeraasa la fcTB«ttaaaleD. TCS
ataoraalltlaa. aad krpcrnrlcaaia.
I1IS1S; dlSSCVBI: 1DOLTS;
cijtiOTiscniit gissisis;
BtPISIEISIOl; BLOOD SBBUB:
CCBHSlTtTl miOHIOIS; C1D8HS:
CHCI09; CBBoaina: LITHIDB;
tienstnt; nosrsnsoos: POIISSIOB;
SCMDS; tllC: SlOUCCtrauHTIOl;
tlllKIIS 1HIB
( 1 saaplad at rat* of 1 1/aln, 2-10
ala aftat bnralag * arc vaiaiaq rods.

DilTcrsltr pkyalca shop, Tlorlda

Tionot; linns; Bi»TB: cucins;
cno>n«: cnomB: CCP»I»; IBOI;
HID: aiieiiisE: ncm: foiissiim:
SOlTIl; fnillOi; T»1BI1!I: II »C; 118
*oimto«: FOBIS; iievsmu
itMsrann; tiici nirairs
t| Coatrolt

laanisg dlsaalad and aerial 3rd aid
«tb grada atadaata la Caaada.
citcnu MSBSins: roussina;
SCCHJB; CUJBTOB; COB11T; COPPER;
isci: ism: uicmsz: ziic;
cncBinx; LiTHina; uncogT; sntis-.
nit: cnxtDizi: ciiiDi
1BTIRE1CS

Blaraabaaa. H. I.
Tleisctiaa, I.I

Icnold.'j.
1975
lancat
1(19ia) :1008-1016












•kselxzon, K.E.
Desaedelevc, E.G.
Johaasaov. T.B.
»ioc»e»ter, J. «.
197«
laaals of Occupational
IT?1«« 19:225-238




Pihl, 1.0.
1977
seine*
i»a(a3i3i:20*-20t





(HIT MSI)
                                                                                                                                                                               NJ
                                                                                                                                                                               Ul
                                                                                                                                                                               VO

-------
  Potassina
  7MO-09-7
  K
  >t*  39.096,  HP 63.2 C, BP 765.5 C, Tt  100 mm  Bg  at  590  C
                                                                                       (COBYIBVED)
TISSUE

M02
Bair

















>>03
Heart







Ezposvn Boon





























1BU.THCU
HITBOD



















Plaae photometry








BOBBEI
OF CASES



















al «
b) 7







BAEGE




















a) 0.035-0.086 mSq/g
b) 0.068-0.082 iZ9/a
let »t






BUI




















a) 0.063 * or - 0.013
aEg/9
b) 0.07* » or - 0.006
aSq/g
let >t




61BI1U IIFOEB1IIOI

l«rl*>. 2« t«pr«sentatiT«
Ft«-aaalysia tr«at>«nts arc
tabilat«4. Ike feasibility of a
tollatic, no-»«s» policy foe kair
analysis is out lined and sapporteij.
flTII*; TB»CI BIMSITS; BUB:
ItSTBiLIl; niSUBMZBT SBTBODS:
CIT1LS: PEOTZIBS; COIPIBlTIfZ
ETlinniOBS; 110BHOS; MIIHOIT;
ISSIIIC; BIBIUB; BIOB1IB; CIDRIDH:
C11CIDB; CnCRHBi CnOBIDB; COBilT;
CCFPIB: 3111IUH; GBIB1BIOB; COLD:
IOBIIE; IBOI: HBTBlBtlH: LUC:
SIGSISIOB; IUS1IESB: BBKCDRT;
cciTBomi; imn: PBOSPHOBDS;
pcTissran; SUSIDI09; sBtzBim:
siiicoi: sjiTKB; SOOIDR; STBcnivB:
sniroB: TII; TITIIIDB; TOIESIBI;
?i«c; zncointB
a) Sxlden death fros ischeiic heart
aiaease
t) Sullen oeath fro« ttaaia
Veatcicalar ayocardiva

< 60 TC olds

B1GIBSIOB: POTISSHJB; BZ1B1 EIS.B1SBS:
tiropsizs; BfisT: imis
I lirlBBICZ
t
Chittleboioagh, S.
1980
Science of the total
taTlroiMat 14:53-75















JohasoBr C.J.
Peterson, D.8.
Ssitk. Z.K.
1979
laericaa Joornal of
Clinical latrition
32:967-970


Piopaae
7«-98-«
C3-H8
SB at. 09, BP -189.69 C, BP -«2.1 C, TP 100 •• Eg at -79.6 C
TISSUE
MMAk
Breath










EIPOS02B ftODTZ












illLTTIClL
HETBOO

OC/HS










VORBEB
OF CASSS

_










BUGS

Vot detected— 2. 2 noXbr










(BAB
0 8 Qd/hr











GPItlll IirOBBlTIOB

•etabolias. Bo other details giYea
Cryogenic saipllig techBlqoe.

Bealthy eilitarr and civilian
eaployees, n.S. air force School of
l«rospae« Bedieii*, aaes 23-*7 yr. 3
stokers.
tlBZBUBS; CBIOTIHTBC 9TDEOC1BBOIS:
CBIOKtn OI6IBTC COBPOOSDS:
CBIOBOBSBZZBZS; naOBIBE COBPOOIDS;
III1TB; 1ICCBO1S; THIS; » DOITS
BZnBZBCS
Conkle J.P.
Caap, B.J.
Sslch, S.Z.
1975
Archives of
Environmental Health
30 (2): 290-295






-------
 fropaae, 2-aitro-
CJ-I7-B-02
H 89,09,  BP  170 C,  TP  TO  •• Bg at  IS. 8 C
IMSOB
sao;
Breath











BTPOSBBB BOBTB













iiiiTTicit
KTTOD
SC-BS












Of C1SBS
S« (3*7
staples)











MBSI
lot qlrea
•











mi
O.aos nq/1
Seoaetric











eiitUL urasRitioi
Masacad at 25 C aad 760 aa Bq
11.1V occvrraac*
loer aid upper oae-SlqM Halts
0.111 ud 1.3* ftoyi

laaltkr. t8-JS yr old. noaaMklaq,
artan blacks and Caucasians.
Cbicauo, II. Ilqldlr coattolleft
«Dcriae«tal eoadltloas.
CB1CBIIITBB BTDBOC1BBOIS; TOliTILE*
cesmc coBtcnos; HBJLHE HKIEBS-.
HHiUTIOl: 5BT1IOLISB: BETlEOlItES:
popirnTioi iiposintB: OBB»« IBEIS
EEIEBUCB
KrotoazTnski, B.K.
Brnaaav^ G. R.
O'ReUl, B.J.
1979
Jotmial of Analytical
Toxicoloqi it 225- 23%







Proplonie aclj. 3-aaceapto-, etkyl aster  (S CI)
l£op«BOle acid. 3-iorcapto-, etk^l eater  (9 CI)
:t«6-06-l
e«-aio-o?-s
ni  13*.21
TISSOB
aao«
Braatk












BXCOSIIB BO1RB














alULTTXCaL
Hit BOD
SC-BS













MBBBES
OF ClSSS
W (317
samples)












ttlEI
lot given













Ull I
5.3 m/i
Geoietrlc












SIieBlL IITO1H»I01
reaanred at 25 C ud 760 aa Bq
21.2* occacrence
Lower aad apper oae*slqia llilta 2,S
aid 11.2 9Vl

aealtkr, 1S-35 re old. vonsaoktaq.
at tan blacka ud cancaaians.
CUcaqo. II. ElgldlT co»troll«l
•ipcrlaeital eoadltioia.
IBUTB; ElCCBOLS; 1111 IO1S; 1DQ1T5;
Ctla»IliTlg BTOlOCaSBOIS; TO1ITHB
CtSllIC CQItOQIDS: SB11TH B»HB5S;
iisiUTtci: nmoiisH: BITIBOLITES:
(O;HUTIOI BIPOSIBB: HEBII HE us
SMIBISCB ' |
Frotasiynaki, S.K.
Bconeaa, C.a.
O'weill, H.J.
197*
Joacaal of laalrtleal
Toilcol<*31 3: 223- 23*








  iroplophmoae (8 CI1
  1-PTOpa>o«e, 1-phanyl- {9 CI)
  S3-55-9
  M-H10-0
  B« 13«.2, RP 21 C, BP 218.0 C. TP 1 a* ft? at 50.0 C
MSSUE
MOT
Breath

ziposim BOUTS


ifumcii.
BETBOD
GC-BS

IDS BIB
OF CASKS
5« (387
euples)

EIIGB
Vot givea

REII
0.261 ng/1
Geoaetric

GEHBIL nfOMUIOl
Beamced at 25 C aad 760 aa IKj
2*.a« occ«ct«Dce
lever aad neper oae'Sigia Hilts
0.05* a*d 1.1» nq/1
BcaltkT. IS- 35 it old. nonsaoklnq.
actan blacks aid caacaaiaaa.
Chicago, 11. Biqidlr coatcolled
HIKB-, IICCBOLS; IlltjoiS-. iOULTS;
CB1OBI»»TID ETB50C4BBOIS; TOltllLS
CECinc COIfCnDS; SMITH BlIiBDS;
1IBIIKICI; SETJKL1S1: BET1BOLITES:
ECPfltlTIOf 1IPOSUBE: 18BH IBflS
fiZTBBZICB
KrotorryasXi, B.K.
Bmnaaa, G.I.
o>Welll, B. J.
W9
Jouraal of analytical
Tozicology J-.225-23*


-------
         »lcohol  (8 CIt
  1-tcopMOl  (» CI|
  TV23-»
  C3-«»-0
  « «0.1,  W -117 C.  OT  97.19 C.  n 10 M *t lit W.7 C
tissrrt

Bnatk










**09
BCMtk











HIPO50IS xore
























imrrtoi
»mo»
ec/ss










SC-BS











IVBBEt
OF ClStS
S









......
S» (387











iliei

lot d«t«ct«4- 1400.0 ««/kr









	
lot glT*a











•Ell

175. « «j/kr










21.1 »«/!
MOM trie











BEIIUt Xiromiioi

CecpoHd related to oorial
Mtabolln. la other detail* aim
cryogenic saipllBa tecktiqve.

•eeltfcT allitarT Aad cirillav
**plOf*n, t.S. Hi rorc. school of
Krorptc* KllclB*. *?•» 23-*7 jr. 3
s*ak«*.
Btnns; cnatiHTiE BTDIOCUBOIS:
cnoinv oteinc COSPOBIDS,-
CBiOMinznis: ruoun COIEOORSS:
E1IITB: ItCOBOlSt TIUS: 1D01TS
!»•««! »t 25 C MJ 7«0 n aa
50. Jt oce«rr«e«
tCMT Ml IppW OU-SlgM lllltl 3.9
ail 11*. 1 »q/l
B»althy, 18-35 TC oil. ooBiMklK;.
vxt<* blAcks ud Cftcotflua.
Cklcaao. IL. llgldlr coattJllod
• iporlMitil onaitlooB.
MIITB; JUCCBOIS; IU.HOIS; 1DDWS;
CBIOIIUTZD EniDClIBOIS; fOllTIl!
cusirrc COBPCITWBJ: asirrs BIZISDS;
IHUIIIOI; IET1J01ISB; *M»BOimS;
POPOIIIIOB ttPOSVEB; 1SB1I ISStS
tERSEICE

Covkl*. J.P.
c«»p, B.J.
Mick. B.I.
197S

VBTicoBBental Maltk
30 (2) 5 290-295





rcotamrMki. B.X.
Iramtc, S.3.
O'Mlll, S.J.

Joirtil of lutytlcal
Toxieoloaf 3:225-23*








Prapria  (• Cl)
l-Pro»T»« (S CI|
T«-99-7
CJ-»«
•i 40. »s. nr -10* c. tf -23.3 c,
                                     387C •• 19 «t 20 c
TtSSBI

BTMtk











Etpajots lomi













1 iiitrticit
•ZTHOD

ec/HS











fVBBES
OF C1SSS

8











MKE

lot 4«t*ct«d-2.3 mf/kr











W»I 1 GIltllL IIFOK111IOI
t
1
I
O.S «g/kr ( CC*F««I] c«lit«A to nonsl
1 Mtabollsi. lo ot*»t tetill* 5lT»»
1 Ccyaqvalc mpllaq teclniqn*.
|
1 B«tltkT Illitur ud clTlllu
1 «plOT««», 0.5. tic P»c« School of
{ l«ro*p«e« ftdleln, tgn 23-*7 jr. 3
1
1 mints: ciiotimm miocitaois;
I cnosm omnc coipanvs;
I cnoBotmtns: nvoan coRpogim;
i mirs; ticcioLS: TRIS; IBOITS
i
uniEin

Coakl*. J.]>,
C««p, 3.J.
«*lck, B.E.
1975
IccklTci of

30 (Z): 290-295







-------
 llfcldiai
fb
It* «S.««7«, IP 39 C, «P <•• C,  n 10 mm B? at 3»0 C
1ISSV1
Mil
Braia
»»«
, lair
Mil
••met

RIOStltl tOOTI




aMITTXCU
RETROD
n

n

»n»BEt
or cure


•t 7
b| 3

MICE | Bill | GtiniL motlatlOI
t 1
< 1
1 1
1.6-4.6 »9/9 (nt «t) I »1 3.0 » or - 1.2 I a) laics, c*t*bru, 6 mblacts
1.«-2.« «j/9 (»«t «t) | ao/g f«at »t) | t) F«ial*B, c«r«brn, 3 *«t »tl I b| 2.3 « or - O.M 1 c| Bal««, c«c«b«U». S nbjecta
1.1-3.* «j/g (nt «t| | uf/g <««t it) I 4| F«aala>. oanbellaa, * aabj«cts
|c| 2.3 * or - 0.*3 1
I «9/9 {»«* *t) 1 Tcoi a qcoip of *1 a«topsi«i,
| d| 2.6 * or - 1.0 I fonacte n«lcal eza*lBatloi«, Japan.
1 »9/9 (««t »t> I ••!•>. naa 19* 10. t ji. r«ul«s.
1 | a«ai ai« 37. < yr.
1 1
1 i TSICI niRtiTSi » BIOPSIES: jwii:
1 i itniitus; aisnic: cunos; COSU.T-.
1 i cctoixm; ccipn; iio»: aitcrai;
1 i ncigi: iieitsioi: lueinsz:
I i iranm: iinnoir; SCMDIVI;
1 i snni»t Titimi: finoina: IIK;
1 i sciB: noviitt lira: KIDIIIS;
1 | CIBMB89; CMtSBllDII: IBlEt; HOSCLES:
1 I «UOtIMl Slim: tOKS; 1OIT1:
1 | IR1LS; COIPUKITB STU01TI01S; SK;
I | ICBIISIC RSIICIIE
1 1
1 1
1 1 MTiwt. 2» npc*>nta«iT«
1 I ir«-nalfili tr*atamta ac<
1 4 tahml»t«4. Ik* faaslbilit? of a
1 1 lollstlc. >o*«aaa policr tec hair
1 1 aaalTaia it emtll»«a aid ««it«ct«i.
1 1
I i mm: mici nmirs; HHJ,
l i usriiin: magunn IETBODS:
1 i CITU.S; pwmiis: CCHUMITITI
1 i iiiwiTiois-. uvinm; uriMit;
1 i aisnic; niioa: Bioain; ciMim:
l i cuctoi; cticciH: cnoaiOH; coetLT:
1 i cettes] ettmn: SIBBIITTIB; SOLD:
l i icBtni 1101: iimanra: i»i:
t 1 H1SIBSIOI: BII3I18SI; mCUIT;
l i ICITBOIIVIS nciiL: PMSFHOSUS:
< 1 COIUSNtCl SraillH; SILWOT:
I i «ttico«: sntit; sotnt; siieinva;
1 l sutrns; Tin imntn; tvi«srn;
1 l tiic: SIICOIIVR
• i
I t
•) 1.2-8.1 «g/« («t *t) | a) 3.» « or - 2.2 1 a) ial«<
b) 1.I-2.H *q/l (»«t «t> | » | t) Ma*l*«
1 bt 2. 1 » or - 0.1 |
1 aq/4 (>*t »t) | fcoa a qro«t at *1 a«top«t«*.
1 1 fot«a«lc Kdlcal •zailaatloM, Japan.
1 1 lain, Mai «qe «0.« it. r; COBU.T;
i i cBiQun-i-, cemi; noi; Hucnt;
1 i iimn"!: auitsiOB: »ien»t;
l i tocTDni; miBon: scinoioa;
l i sntiioa? tRinoi: T»«BI«I; me;
i i SCLD: BMBIIII iirai neitrs;
1 i ci*fwn»5 ciiracun: HUT; BDSCIES;
l i P net sis: sfttti: latest lorta;
l i untLS: coiimtm naimiiois; sti;
i i music aioicxn
i i
(HIT PlOE)
raiEncz
Tikaoa, H.
Sgzaki'Tanioto, a.
laaao, K.
Terai, 8.
1««0
IrcblTM of
CBTlconMital Health
35(1):36-a«
Chlttl«bocoagli. 6.
1S80
Seine* of the Total
EBTlcaaMit 1»: 55-75
Tnkava* R.
Satoki-Tanaoto, a.
auaa, K.
fatal, H.
mo
arealTM of
KnTlroiMBtal H«alti
35(1}:3C-a«

                                                                                                                                                                                          to
                                                                                                                                                                                          o\
                                                                                                                                                                                          OJ

-------
7MO-17-7
III
Its 85.»678, Bf
                39 c, B*  sea c,  is 10 » E« at
                                                                                        (COITXfTCD)
IlSSHS



Mil
Kltaer



















a*,t5
Kidner




















MIS
lime


















BTPOSJSS BOVt


































































lialYTICU.
HTTBOD


«




















n





















n



















JOBBSB
or casxs


»l 15
tj lot
giT«n


















•) 8
of 9
q 12



















) 2
) «


















BIKE



a) 1.0-6.0 B«/g f»t it)
bl 2.3-5.2 agSg {ret «t)



















a) 2.»«-8.40 11/9
b) 1.50-13.5 09/9
e) 2.01 -4.0 a»/«
•et irt


















) ».«-9.7 »j/» (net «t)
) 2.7-5.* og/j fwt *t|


















nil i GII mi IITOIUTIOI
1
i
l
a) 3. 3 » or - 1.5 I •) Bales
ag/y (vat »t) 1 t) F«ial«s
k| 3. 1 » or - 1.6 I
H9/9 t»«t »t) | frot « groop of f1 autopsies.
1 tar««te ••itcal •mlnatiou. Japan
1 S«l«s, i«an «g« 40. C rr. r«al*s.
| i«a* a

IT vat >t | ^etl*BS 1 teceaie^ retloerr and n«lter I >ozt«rs, «ge» 55-78 yr, exposed to 1 b«a*y let all 1-3 d*ea4«s. Us* ( t«tvM> ceticeoeat a>4 d«ath 0-1.5 fr I it group I aid 2-19 Tt. gronp tl. 1 Cntcols, aqts «3-72 Tr, »ho liwd 50 J ti fr« tke faetorr. 5v«l«i). | 5IBDH; C»1TEBS; KID1ITS; 1ITSB; 1 I OSES: CO«P»B»TITI rfimiTloiS: 1 IIDITSTSIll ITTnE»i JBlSOBEHIT 1 (ROODS; UTISOIT; IBSZHC: CUBIOH; 1 cism; cpBOsmd; cam?: casrst: \ ccto; isoi: luieumt teia: 1 niGinss: stscnEt: HOITBDIIOH; t tsosjHoins.- BBBlDios: scaiDimi; | SlmlDS; StlTEE; Til; TOIGSTCI; 1 ZliC; BHITH RlEiRBS: IJDUSTSUl I ttlRSi SinTRS; TH.1BSI3S 1 9.7 * or - 0.07 | a) Bales 1/y (ret irt) r t) Females J ». 8 » or - 1.4 I g/9 (net irt) 1 rcos a qronp of £1 jatopsles. 1 (oreasie >«41cal etaalutloss, Japan. 1 falsa, «ean tqa 90, ( Tr. Itnla*, 1 nan aqe 37.1 jr. \ l nice nmrts; mopsrzs; Jtric I iigami; nsnic: cumin; COBUT; 1 CBBOBIH; Corn's; ISOI; IZBCmT; 1 itnoi: iiemsiOB; aueuisi; 1 SOBinWS; ItTIHOfT; SCWDI99; 1 snniin; Tinim; TIIIDIOJ; zinc; 1 Gain: Bioniit; ii»i: KIDICTS; 1 CHEStBl: CIBEBEtiBfl: BMSI; BDSC1ES; 1 Eiictiis: spusi; LI«GS: aoni: < anus: ccipmnrz ETUHITIOFS; six: I ICSMSIC K1I1CIIE i IHFEEnCI Tikam, B. sazakl-Tasasoto, 1. Jtaano. S. Teral, B. 1980 IrehlTcs of Enfironsaatal Health 3S(U{3«-»* Btoae, 9. locaberg. 6. ff«3t«r. f.O. 19AO Science of the Total Environment 16:13-35 Talcaia, R. smiaU-I«sa»oto, S. inna. E. Teral, 1. 1980 IrcStKs of EnTic«nMi.tal Scaltk 35(1):3C-4« (•EIT PaSE)


-------
ItbillM
7MO-1T-?
n
Itf 85,a«7«, m 39 C.  B* 688 C,  TJ 10 H Rg at 390  C
TISS5I
MIT
liter
»«»
tm»g
*ei9
in?
nans BOUTS



iiumcu.
NETIOI
n
n
it
IUBSEE
T CUES
B
9
11

a) «
b) 9
4 11
lives
3.11-9.10 •»/»
1.W-S. SO ao/S
O.C7-T.»fl «o/g
t «t
.6-3.3 19/9 (««t »t)
•1 2.50-7.»9 ag/g
b| 1.W-5.70 qj/g
d 1.0-9.9 ag/g
«lt It
"BUI " i siiim, HTOHHXOI i amines
i i
t i
i 1
5.20 «n/g I •) Control* I Bcaae, 0.
a. 01 «g/9 I bl inker groan I 1 foraberg, 6.
3. M «g/g 1 c) Barker grow IT 1 (ester, P.O.
t «t 1 1 1*80
itua 1 C«c«u«l c*ei*«T a»4 BMltec t Science of the total
1 *ork«a. *«•* SS-T6 yr, elposed to t EvrlronMBt 16:13-35
1 t*»rjr MtalB t-3 tffil-*s. !!•« 1
1 tctma c«tlreM«t itA dcatb 0-1.5 ir |
1 Is group I »4 2-19 yr, group II. 1
1 Controls, «q«i «3-1J yc. vtto Xlwt SO I
1 lii frei tie factory. S«e4«. 1
1 1
1 siion: ciiifiES; it Dins; IITIB; t
1 IVIGS; COBPIMTITB KTIIOITXOIS; I
t IlDOSTitll. nolEd: «!»SflSSSCTT |
I IITWOS; IRIBOII; lISEIIC; UDim; 1
1 cisnui: cmoBXni; COBILT; COPP»: I
| 601,0; INI; URUIII; LEIBs I
1 flivsmsi: BncmiT; 9OLTBDK«on: (
I tnsMOBis; inipioB; SCMOIHB: i
1 sn/iBiira; sunB: it«: TOIGJTE*: i
| IIIC; (II11B HIIBBS; X»VSTBIlt 1
I tints: sBums: uumm i
1 .!..._
I 1
2.2 » or - 0.90 ag/g 1 «•!«• 1 Tnkava, B.
(««t it) 1 1 Sankl-Tasuoto, B.
1 fco« a «ro«v of (t aatop«l». t imo, K.
1 Coceviic aejical •xaaiBatioms, Japan. 1 Tecai^ B.
t Bil««, mtta age *8.t yx- Teaales, I 1*S»
1 iea« agat 37. • yr. I IrcklTe* ot
1 1 Imlronaeatal Health
I TSUI ILEBtlTS; 10TQPSIIS: JUIBs I 35(1> : J«-«»
I noBinm nsniCi CIDBI«B: COEILT; I
I CBSCS11W; comi; JIM: Encnsi; i
1 1ICIDB; 1»e»ESIOIl: BUeifESB; 1
t lOeiDTBH; IIIIKOIT; SCiWDITH; I
1 SILtnia; ITTUin; tllltlDSt 1IK; |
I ECIDI B*o»Bt; LiTN: nuins; i
1 ciBKBW: cnranuiB: BSIBT: BDSCIES; i
I Clients; s»LRf: iwflS: loiti: I
I amis: comtiTin zruoitiois; SEI: i
I ICRKSTC BltlCTX |
i i
1 (
a) 2.99 m/g 1 •) coatcoli \ Bcu«, 0.
b) 2.6* tg/« 1 b> (orlcer group X 1 lordtwrg, G.
c) 3.«2 aj/1 t •=! «ot\«c gceip TI t Hester. 7.O.
Vet »t I r 19«0
lealaas 1 tcceasel reflaery aid smelter 1 Scieace of tie Total
1 lackers, aqe* 55-76 yr, eiposed to \ EaTlroaieat 16:11-35
I heavy «etalt 1-1 4ecales. Uee t
I tctveem letiteseBt »a oeath 0-1.5 jt |
1 It grow I anl 2-19 yr, groep II. I
I Ccntrola, ag«s *3-7i yr, vho llted 50 I
I kt fros the factory, svedea. |
1 1
I SSICII; CWHIBS: KIS1BTS; LIT It; I
I IOISS; COBV1B1TITI EV1101TIOBS: |
I I»BSTEtll BT6IDR; SUSDHmT |
1 MTBOD5: iiriBon; usmc: caosim-. <
1 ctsnn; cnoBinv; COBIIT; COPPEB: i
t GfllB; I9O»; IURHUOB; tUD; t
i B1K1BE5ES tllBcaiT; 901I3D11TIII; I
1 teosPBoirjs: BtrBUJnrn; scivmtm; t
1 sniBTfi; SIITEB; Tt«: TOB«5T»; I
4 TIBC; IBUTO B1Z1BDS; UDOSTBUL |
1 1 m«TS; SBT11EBS; IBIIDIITIB I
I 1 1
• " (BEIT MGE)
                                                                                                                                                                                           to
                                                                                                                                                                                           a>
                                                                                                                                                                                           Ul

-------
Ilbl4i.il
7440-17-7
It
Itl 8S.4678, B? 39 C. BP 688 C. T? 10 u Bg at  390 C
TISSOE



4420
Biscle

















4421
Fasereas

















4422
Spleen


















EIPOSOU SOO





























































alUTTICU
METHOD


U


















M


















a



















nnst
OF CUSS


I) »
b) 3

















a) *
b) 3

















> «
I 3


















UIGS



•) 3.3-5.6 ng/g (Mt >t|
b) 2.1-5.2 «g/g (vet vt|

















a) 1.3-6.3 uj/g (vet «t)
b) 3.1-*.8 sg/g (net vt)

















) 2.7-7.0 vg/g (vet m)
I 2.5-5.1 «g/g (vet wt)


















BUI i siiiin iBFOBRHioi
1
i
I
a) 4.2 * or - 1.0 1 •> Biles
•g/9 <«•* vt) | I) resales
bt 3.9 * or - 1.2 I
ng/g (rat it) I »ros * group of C1 aatopsiei.
j forensic •eolcal eiasinatlcns, Japan
1 Rales, »«aD *9» »0. 6 rr. r«alu.
1 i«an «q« 37.* rr.
^
I IJICI BLBBBIIS; HJTOPSHS; J1PII;
I itoBtin: IZSCUIT;
1 mini; !U6izsiia; mtsntst;
t BCSIOI11: 1ITIBOIT; SCIIDIDB;
1 stiEitvs; TiiiniR: Tinoiua; ZIBC;
1 eoiD: B80HHI: LIT IB: nnns;
| CISIESOS; CHZBE119B; HIIBI; BVSCL3S;
1 Fiicaiis; SFiixi: Ln»GS; IOBTI:
I 1 IT HIS: CORFUITITE Bf HB1IIOIS : SIX;
I ICRIISIC HIDICI»E
) ».2 * or - 1.7 | a) Bales
g/g (vet vt) I D resales
) 3.S » or - 1.4 1
g/g (vet vt) | Fcos a group of 61 autopsies.
| forensic twaical ezasiaatioas, Japan.
j Bales, seas age »0. 6 rr. resales.
j iea> age 37.4 rr.
1
1 TBICE six«:iis: itnopsiss; Jip«i;
I uvRins; iBsiiic: CJDMOI: COBILT;
I cntoarus; COFFES; IFOI; IEKDF.T;
1 tiDioa: BiensiiB: snoiitsB;
| BUBIDIll: IRIHOBT; SCilDIOB;
1 sntnm: TiT»»TOfi; IIHBIB«: ziic;
| GOIB; BSOnil; IITBB: KIDflTS;
| CIBEBBB1: CEBEBZ1LOR: BUST; IVSCLZS;
| F1ICBE1S; SFtEEl: 101X53: IOBTl:
| 1FT1LS; CCSPIBHITE BTU.B1TIOHS; SSI;
| •OHIISIC BF.DKIIE
1
tBFBBEBCE



Takava, B.
Svxskl-Iasasoto, B.
tsano, E.
Teral, 9.
H80
Irchlves of
BOTironasatal Health
35 (1) : 3«-44











Kkava, B.
Snlaki-Taausoto, R.
Isano, K.
Teral, B.
1980
IrchiTes of
Enrlrotseatal Health
35(1) :3«-4<











rakava, B.
SnzvU'Iasaioto, B.
liana, K.
Teral, B.
1980
Ircblres of
EnTiconsental Health
35(1): 36-44












                                                                                                                                                                                           to

-------
7MO-20-2
se
at* M.«S». Bf 1S18 C. tt 2B« C
TISSBB



023
ketta















M2»
Brain




















«25
Heart
















MSBII MVfB




























































IBUTTICIl
BRBOB



















I





















Ik

















BBBBSB
at cms









































al 6
bt 2
















HISS



BOB* detected
















a) IOBO detected
b) Km* detected
e) MB* detected
at (OB* detected


















B) < or • 0.001 ao/e, (n
•t)
b) Boa* detected















B»I i snniL nroiBinoi
I
i
l
oae detected | talea
1
| ftOB B OTOBP Of C1 aatOpSl*B,
1 (areialc aadlcal ezaalnatioea. Japaa.
1 Baloe, Beaa ao* 40.6 yr. leaalea.
t Baa* a«* 31.* If,
1
l TIKE nums; tnovsKs; JWH-.
I KUBIBVB: kBSBtlC) CaDRIBB; CO BUT;
I CEBOBCTBl CCfPIlI ItOI; BIBCOIT;
1 innBt siei>sma: BMSHZSI;
I SBIIBim; iBTIBOIt: SCIBBIVB;
1 snnrivB; line;
1 CCIBs BBOBIII; 1ITSB; tlDIITS;
l ctiiBton-, cEitBBtuiiit tnun; MSO.K;
I BilCKkS; SHIN; mwjS; 1CKI;
l Bitats; cotsmnn trunnions; s:x;
I fOtEBSK BIBKIBI
1
a) BOB* detected I a) Bilos, cetebcai, ) nblecta
b| BOB* detected I I) fcialee, cerebna, 2 >«b]cels
e) »oae detected | c) Bale*, ce.nbell.aB, 8 mnbjecta
at BOB* detected I a] Teaalea. cecebellaa. 5 «ab1ect»
1
1 HOB a 9COBV of 61 aitopiiea.
1 formale aedlcal eiaaiaatloaa, Japaa.
1 Balos, aeaa aoa BO. 6 rr. Tesalos,
t te«a 19* 37.4 Tt.
I ItlCB BIBBBBTS; WTOPSIKS; JlPlI;
< UVBIIOI; 1BSWTC! C10BIBI; COBUT;
1 CEBCBIBB; COMSIl 1BO»: BIKBIti
1 IIBHJ": HUKSiOB! Bueiiiss:
1 SQIIDI^B; aBTlROBT! SCaBDIOB;
< stiiim«-. tiiiiivii; mum; live;
1 6CIB; BI08IBI: LITEB; KIBB1TS:
1 CIBIBI9S: CZIDEUKt «»lt; BHSCLIS;
l ciictttj; spitn: mtsj; ten*;
1 amis: COBTUITITB CTILOITIOBSJ sn;
1 fc^nSIC BEBICIBI
1
t
a] lot 9iv*B I a) sal«
bl Boa* detected | t| Teealei
1
1 ICOB a qroap of 61 tttopsl**.
1 (oc*BBlc aedical eiailaatlon, Japaa.
1 ealea, lean aqe ao.t jc. Fenlex,
1 BCBB »9* 37. » TE.
1 tt»ci sunns: nrrotsus: JWIB-.
l niBimn: ktstnc; CIBIIOB; COBM.T;
I cttcHH; canst: ttat; RBKVK:
1 IIBIB4: Bk«lESIVB: UlGtBBSX;
1 BtBiotm: imsoit: SCUDIOB;
1 Stllim; TlTIBlBBi TkBU)lnfl; ZIBC;
1 6CIB; BlOBIIt: IXTBI: XIBIITS;
1 CltBBCIM; CnEBCUVB; Kilt; RVSCLIS
1 (IfCBIkS; StlBSt; In BUS; lOMk;
1 units i ccspiiiTiTE mtoiTioiS; six
1 ICBtlSIC SKICIIB
tBTBIEVCE



takava, B.
Sankl-TamBOto, B.
1B*BO, B.
Total, a.
1*80
lEchlte* of
EBTlcniaeatal Health
(5pt :3^-a*









TBkaira, B.
svzaU~laviBOto, B.
liana, E.
Total. B.
1*80
IICklTCB Of .
BBTlcoBB*atal Bealth
35(1|:36-«














Tikava, B.
S%nkl~Taaaao^o, ai*
laaao, K.
Terat, B.
1*80
atckiTu of
Ca*lcoBB*Bt*l Hoaltk
3S(1|:3»-««










(*in pisi)
                                                                                                                                                                                            N3

-------
seaadian
TMO-ZO-2
sc
ItB M.«S5«, IP 1538 C, B» 2*32 C
                                                                                     (COBTIBVBD)
TISSOB
MK
Kldner
••27
Xldaer
1
1
• •20
IIPOSHBB IO


I
i
a BitniCal
BSTH09
M
n

BVBBEB
OF CIS3S
a) 10
b) 2
a| 8
b| 20
a) K
b) 3
IU8E
a) < or • 0.003 ag/g (•
wt)
b) BOM detected
a) < 0.0001-0.00053 03/7
b) < 0.0001-0.0020 aj/j
Bat wt
< or - 0.01 ag/j (wet
t)
lone detected
SSiB 1 CtBIBal IBFOBMTIOB 1 BEFEBBBCI
1 1
1 1
1 1
al Bat given | at Bale* I tgkawa. B.
b) Bane detected | t| Fesale* I Saxaki-Tasnaoto, S.
1 1 aaano. t.
| fcoa a groat at 61 eatepsies, I Tacai, B.
I forensic aedlcal •taalBationt. Japan. ( 1*80
I Bales, Man eg* ««. 6 TC. resales, ( Archives of
1 Ma* a 1
1 1
Bat gives | t) Bales I Takawa, a.
Boae detected 1 1) Females f Smakl-Tasaaato, 8.
1 I laano. K,
I Fc«a * ?coap of 61 aatopsleg, I Tecai, B,
f (oces*ic Mdlcal exaaiBations, Japan. I 1980
1 tales, aeaa a«je »0. S yc. resales. 1 acealves of
I Man aae 37. • vc. I Bnviconaeatal Health
1 t 3S(l|:3«-««
1 TSICE ntetnst IDTOFSISS; JIFIB; i
f nOBIWOT; ttSSBIC; C1BBIDH; COB.LI; I
I CnCBIOl: COFPES; ItOB; SEICOBT: 1
1 IIDTOII; HiensinB: UBGIEESS; i
I Ft'ioini: iRiBOBT: SCIBDIOI: i
I stiBBiia: TIIHIOB; TiuDias; life: i
I GOIO; BSOBIBf; tirn; RDBETS; I
1 CEBCB£0T: C7BEBE1LBB* B3ABIJ B0SCLBS; I
1 pjicsm: spiHM: IVBQS; tent: i
| "TTUS; COBCUITITS B»ttUtTIC«S: SBtj |
| YCBEB8IC imiCIBE I
1 1
                                                                                                                                                                                       •00

-------
sciadina
7MO-20-2

»tf «,»55». 0? 1538 C. B? 2832 C
                                                                                    (COVTZVOXD)
IISSW
M24
Ilnr
M30
VMO
»«31
linn
SITOSIK torn



lIUTTICll
RRMD

U
M
•ram
or cisss
8
20
) S
) 2
4 »
1» 9
0) 11
11IGE
< C. 0001-0.8005 sg/g
< 0.0001-0.0029 a«/g
t lit
1 < or • 2.7 «<|/ qtoop I aid 2-11 TC« qtatp II. I
| Cemtiola, a?«a «-72 re. «lo Iln4 SO I
| Hi ttoa tk» faetocr. 5>*daa. j
1 1
I snni; claims; smns; HTIS; i
1 IONS: coiMimn tnuiiioiss i
I iiDTSTiiai iteiiii: Biasviiint i
| BI1BOBS; 1RIIOIT; HSmC: C19MBB; |
| CIS1U11-. CBBOHIUB; COBUT: COPPMJ 1
1 ton: imi: IIKBMMI 1.110; i
1 iimiist; Rncnii; BOITBDIIOB; |
| tBOSPBORBS; BOBIDIHI: SC11DIOI; t
I sninovlTOnaa«tal Bealti
( I 3S(1|:3C-M
1 tiici ncBfiis; IOTOPSHS: jute i
I itOBTIUB; UStBIC: CIDBIDB; CO3U.T: |
I CBICBIOB: copfis; ito«; incms 1
1 iitim: sisHswa: UKIKSK; i
| 1C1I9I9B! IHIBOITl SC»«DIDS: |
t smnn; tutnos: TIIIDIOR: znc; t
| «O19: BIOBI1I-. IITS«5 KIISIIS; |
1 cnnina: CMtszuni; is»i; MSCLCSS i
I PKCSHS; SPIK»: LOBS:; loni: i
I itiits; cowaimn ETIIOIHOIS; sn: i
I TC5M3IC HIEJCIII |
1 1
1 1
al 0.0023 aj/g 1 a) coatrola I >ru«* D.
b) 0.0023 n9/g I b) »ort«r iToan I 1 focdbarg. 6.
e| 0.00(2 09/9 1 c) *otkac ttmv II I Vaster, P.O.
let »t | t 1«BO
lediau 1 t«cmaa4 rafiasry a>« aaaltar 1 Sclaace of the Total
I lorkars, «««s ?5-76 yr, axpoaad to 1 tariroaaaM 16:13-35
I kaavr aatala 1-3 aoealaa. tlaa I
1 tctmaa c«tli*a«at and Oaatk 0-1.5 Tt 1
I la group I aad 2-19 vr, ?co«f II. |
I Ccatrola. agca U-72 Tc. nbo llwd 50 I
I ki froa tka taetory. s«*4aa. 1
1 1
1 si»n: cmimsj iimnss L«S«; i
I IC15S: COBPU1TITC miVHIOBS; |
I iieosmu BteiiB; BSISUBBBIIIT i
| 1ITBODS-. intMII; MSinC; ClMIORi 1
1 CMIOS; CBIOtrilB; COBllt; C0»»; I
I CCID; IBOt; ItfTIUOa; LHD; I
I tiKiitsE: iincnBi: BOLIBBMOT; i
1 H05PB01DS: Bromwi: SCIBSIDB: i
| StUBIlM; SIlTtt; TI»: 10JSSTI1: I
I niC: BSalTB lUilDS; 11003TEHL |
1 nins; sfintRS; TnimoB i
i i
(Itxt flSl)
                                                                                                                                                                                          N>

-------
ScuUw
74*0-20-2
sc
lt» »«.9SS9, B» 153* C. tt 2«32 C
TtSSTTI
M32
nascle
«•»
Paacreas
4»3»
Spl««a
ntosm ton



tUI. TTIC*l.
BWBOB
n
n
n
•ram
or cisss
•1 »
bl »
•I «
bl 2
6
3
MKI
*) ROM detected
b> «>•• detected
a) < or • 0.001 »9/q <«•
•t)
b) ion* detected
< or • 0.007 m/a liet
•t)
Boae detected
un i mini ivmamoi i icnmcB
I i
i i
I I
t) »o«« detected I •} Bales 1 irtaam, B.
b) »o»e detected I t) resales 1 SlxmU-Unwto. S.
I | liana, t.
j fros a groat of il ••topaics, 1 T«r«i, 1.
j for«n»lc ««UcOITI: i
I imtS; TOBPUlTltl mi0>TIOtS: SSI; I
I IC1MS1C tlBICIK |
1 1
a) lot jina I «) **!•* I lokarn, a.
b) »o*« tet«et*A I 1) P«aal«s | s«nkl-Tas»oto. 1.
1 I laano. K.
j Irca a gtoif of 1 1 aatop«i«a, | 1«rai, I.
1 Caroalc Mtieal «a«lutloM. Japan. | t990
I lalcB, Mas «qc «0.< rr. f ••>!«, I Irekircs of
1 f«aa ao* 37.* rr- t CiTiroBMatal Health
1 1 3S(1)i 3«-*l
I met nsnits; mopsiss; JIPH: i
1 niBim; iisnic; cioima; COBUT: i
t CBICMBH: ccmf; ito*; BircnBr: i
I iigio-a; »JSKsro«: BMSIIISI: i
1 inEiain*: imooiT: scinnoB; i
1 annum; TIUIIOT; TIUDIOB; H«C: i
| CCU; BEOBIlt; tITII; ICtDlITS; |
1 ciimv«: ciBZBCiiai; nan: RosciiS; i
1 tncttti; silts*: i BBSS: IOBT»: r
1 «rms: cottumn ETIIITJIICWS; sn; i
1 rcmsic BIIICIII i
i i
I I
) lot gltoa | a| Bal«s | nkam, B.
} Ion a«t«ct«a i t) F«Hl«s | smkl-Tamioto, a.
I | anno, I.
( Icoi * vroif of 61 a«top*i«, I T*rai, B.
I fora*ic xdical aiaaiiation*, Jspan. | 1990
I Rales, »a> aq* »0.6 jx. r*Ml«s, 1 arc>i*«s of
1 a«aa aq< 37.1 rr. I ZaTicoai«ot*l Health
1 I 35{1}:3«-«4
| T»C« nifttHS! aUTOMIKi JU»; |
1 iiUiiTOB; itsmc: ciniDB; COBII.I: i
1 cnnniB; co«m; IK»; BIKOIT: i
1 litni: SI5HSIOB: atis»ni; i
I imioioa; aitnon: SC»R>I«B; i
I snuiTsc IITHIDB: TIIIDIITB: snc: i
I eciD; «ton>t: urn; SIMMS; i
1 CMIBS71: czinnuB: >uit: BBSCLES; i
1 tuciMS: svtni: imos-. iom: i
1 BRUS: contniTiTi iTuoiiioBS: ssi: i
1 tcinsic BfEmn i
' '
                                                                                                                                                                                       to
                                                                                                                                                                                       ^J
                                                                                                                                                                                       o

-------
s«
1M 78.»6. » 170-217 C, BP 685 C, T*  1  ••  Rg at  35t C,  10 II 89 at
IISSV*
M3S
lorta
M3S
float
Blool.
MSB
wkole*
tiNsgiE son*


laqestloa

IMITTICII
BSTBOD
I
Tlaoroaetrr
US
PlvoroaetrT
•DBBSS
or cms

a) «2«
b) 6
33
210
MKB
.0-6.* og/e (**t lit)
a) 0.1 1-0. 60 ng/al
1) 0.2»-0. «2 ug/al
13.3-2«.B (4/100 al
10-3* 119/100 al
BUI | GBIIMI nrOBHTIOB | BRBBEBCC
1 1
. » * or - 3.0 sg/q I «tl«s i Intau, B.
rtt rt) | | Saznkl-Tasesoto, a.
j ttoi a gro«p of (1 attopsles, | laano. I.
I tcrvaslc soaical exaslaatloas. Japaa. 1 Teral. B.
j Bales, caaa age »0.« rr. Feaales, | 1980
| aeaa age 37. a jr. t IrcklTes of
1 1 BaYlroaaeatal Health
( TtiCI BtBBtns; IROrSIBS; J»lf; | 35(1|:J6-M
j itoaiwDS; iBsiiic; CADBUJB; COBILT-, i
I cmcaios; conn; xioi; BSBCOIT; 1
1 iicius; aisiisina: UBetiBsi; i
t BIBIDIDR; iniHon: sciionni; i
I stLBBinH: niuim: TIHSIOB; site; j
I CCID; BBOBIIt; LITI1: EIDBITS; |
I ciBtnm; ctiaziui: BBUI; HBSCLES; t
1 tiBCBiut SPIIM: ia«GS; IOBTI; t
| BtlllS; COHP1BMITE ST>LD1T1OIS: SBX; I
I toiiisic neicin i
1 1
1 1
a) 0.265 ng/il | a) Basldeats at Soatk Dakota a«4 I Bo««, B.
b) 0.29 ag/al I igzroaailug anas | 1979
1 t) n«sll«its of kmo«a solenltecoos | axc&lTes of
I »«a, Eanld clti, 3D. «a«kl} or I Znrlco»»tal Bealtk
I teatklr saiplUii, a-2* «lt. | 3a(C);aaa-ta8
1 1
1 !*«ltaY blooa aoior» of various ao.es, 1
j Scnth Dakota, »Tomlnq, I«biaaka, aai 1
1 lotth Dakota. 1
1 1
1 SltlBTUa; BICOD; HIl; ffUBI; |
I ccapiBiTiTi miOMioss: SOILS ; SOUTH i
1 CIKOTl; lOtTB DUOT>: BEBMSU; 1
I S10III6 |
1 1
17.12 * or - 2.53 I Seaifteats vslaq eatez fcoa veils «ltk 1 TaleatlM, 3.1.
ag/lftO si | 2C-1BOO aq Se/1 | Kaoq. B.s.
1 | Dana, P-B
1 Illaa. BB | Sefclvckter, B.
1 I 1980
1 Itl Hit ICO; BLOOD; S»IB; DBIH-, | 3onx>al ol Toxicology
t SITUS : SBIB1IOB: DMIKIIO IITBBi I aaa BBTlroaMBta 1
I 11IIBIS: POPOUTIOB KPOSOBI I Bealtk 6: 731-736
1 1
1 1
20.6 aq/100 al t Safejects (roi 19 collection sites la 1 Ula«aT. I.B.
1 tke U.S. | Fnbota, J,
1 1 Losoe, T.
\ mtBioa: BoinDnoB: IHIBIIM; i Both, s.
1 HOOD; SBI; SOUTH DtlOTl; K> TOSK: | 1968
t BTCBIK: Bonni: oaio; BISSISSIPPI: i jrcbi»«« of
1 THIS; BOBTB D1ICOTJ: tlSBIB6K>«; I ZBTlroaaaatal Bealtk
1 CUiniBIa; 18IIOU: milll; I 1«:3«2-3»«
I lensiiBi; IBHBSIS: noaiBi: i
1 fttBOWt] TMCE SUBIITS I
1 1
                                                                                                                                                                                               N)

-------
Seleninn
77S2-M-2
Se
»tw 7».»6. HP 170-217 C. B« 685 C.  TP 1 nn Hg at 356 C.  10 an Bg at »29 C
TISS05
M39
Brain
»««0
Brain
•Ml
Hair
•M2
Hair
IIPOSOBZ BOOT

Ingestioa
I
1
lB9C*tioa
IIIITTICIL
HITBOD
n
sc

us
BOBBSB
or ciss

9

30
JIWSK
a) 0.19-5.0 «9/g C»»t »t
b) O.»1-1.« OS/5 (••* »t
c) 0.50-7.» «g/9 (»et »t
4) 0.35-2.2 ag/g (net »
a) 226.S-423.2 ppb
b) 15.2-23*. 7 ppb

2-1.98 ag/g
BUI | 6EBnu iiroiiaixoi 1 BBFBBZBCZ
i •
1 1
a) 2.0 + or - 1.8 I •) Hales, c«t«brm, 7 subjects 1 Tokana, B.
19/9 («t «t) I Pro« a group of tl aatopalvs, I JicehiTM of
I) 1.0 » or - 0.8« I forensic ••dleal eiaiinatioos, Japan. I Enriro»»«ntal Health
119/9 (««t wt) I iales, Man age 40.C rr. Feules, | 3S(1):3«-«*
1 i«aa aqe 37. a ^r. j
1 1
1 Inez niBtiis: iwopsies; juii; t
I lIOBirjB; 1ISNIC; C1DBIUB; COBILT: I
I CBIOBIOB; CCFPES: IBO»: BZBCOSI; |
1 IBCI01: BIGIHSHJB: BlfGlBBSI; I
I IOBIDIOB: 1IHBOR; SC1B9IDB: |
I snmaii: imiioa: nnoioB; znc; i
I 6C10: 9BOBIII; 1ITBR; SIDIBTS; I
1 CIBBBK91: CHEBILlOa: BZ1BT; BOSC1BS; I
1 PHCBIIS; SPIRI: LOBSS; IOBT«; |
1 SITUS; COSPHJTITI ET1101TIOIS; SBI; I
I rOBISIC BIDICIWB |
1 1
1 1
a) 311.6 ppb I a) S* II, IT | Cappoi. C.J.
b) 111.5 ppb | t) Se TI | Saith. J.C.
Fresh lit | Igtopstes | 1981
1 I Jonraal of Inalrtical
1 Ciiadlaa Indiaas, aortkvcst Ontario 1 Toxicology 5:90-98
1 1
I IISBES; FOOD COITlRIBlTIOf ; 1
1 iicosTiiii tciiaiioi; eornaiot i
1 IXPOSVIS; BDB1I 1BI1S; nSBAI ISB1S; 1
I iura poiinioB; aiBcoBi; BIECOIT i
I CISIBIC COBFCOWOS; SKiniDS; 91IIB; I
I BflRT: KIDBETS; IITZB: PLICBIT1; |
I StlZBB; CIBlCa; iOTOPSIZS |
1 1
I F«Tie*. 2* rspresentatlTe 1 Chittleboroagh, 6.
I Fee-analysis treatnents ate I 1980
1 tibnlateJ. The feasibility of a I Science of the Total
I holistic, no-vast policy for hair I Eo»iron««t 1«:53-75
1 nalysis is oatlliei] and snprortei. |
t t
I ittrii*: TPICI nzBCBTs: BUB; i
I msnmn: BZISUBZMBT HZTBOOS; i
1 SITUS; PSOTHBS; COBPlStTin |
1 ITllOtTIOBS; ILOnBVB; 1HTIBOBI; |
| ISSEItC: BISItJB; BBOBIBB; CltBIDH; I
I CllCItHI; CBICBIBE; CBBOBITIH; COtltT; |
1 CCPPBI: sunns: GKBBIBIOI: COLD; i
( ICDIBB: IBOI; LJnBlIDB; I SIC; |
1 BISHISHJB; B1BG1BBSB; BSBCOBT: I
1 (CITBOBBQ8: IICKEL; PROSPBOBOS: I
1 (CTissni: JOBiDiis; samoa; i
1 SIITCOf; SIIRB; SODIOB; STBCIT10S; |
1 SOirn; Til; TITanm; TOBGSTBB; 1
1 IIK; ZIBCCBIOB I
1 1
1 1
«6 » or - 0.** U9/9 1 lefUents using water fron veils «ith I Talentine, J.L.
1 2«-1*00 09 Sc/1 | Kang. B.K.
1 I Dang. P-S
1 lila«, IS | schlachter. B.
1 | 1980
1 III R3IICO; BLOOD; BUS; OUR; | Journal of Toxicology
1 BflLlS; SCIZBIVB; BSIBHIO 11TBB; I and invironaental
I imns: POPHUTIOB ZIPOSVII i Health «:73i-736
1 1
(HIT ?IGB)

-------
77*2-44-2
5«
att 7«.f«. n no-217 c. a* «e? c, w •» •• »g it 3S« c, 10
                                                          •• 19 at »» c
                                                                                    (COM TWED)
TIS5VI
•«*3
•air
4M4
Hill
44*5
Balr
««««
la-art
fosm tom




A lit RICH
HESflOD


TlnoroMtry
»
•0BBM
T CaSSS
42. b)

a) 5
b) 1
a) 8
*1 »
UBS1
0.24-37. J« ng/g
«. 15-121.43 »g/«
.
*) 0.25-1.11 ag/g
t| 61. 2-10*. 5 uoyg
») 0.44-5.0 19/9 (vet «t
b) 0.81-3.7 wj/q (Mt «t
1
1-
ui> I eiinit MFOIUTIOI i nntnci
1 1
i i
0.44 ij/g | •) Coitrol* | Bran, B.I.
O.SO «9/g I fe) Biltifli (derail patieats I Bolsbeckar, J.
dUu | s*ipl«s fre> 7 »calp »it*s 1* «»cb | Stuct, D.C.
1 Irt}«ct | 1471
t 1 clinical ch«*lotrr
1 Cklltl: »BTI1B: Cllim IlltOOS r 24(11)I1»M-2000
i Sinn usiiSK: nn: uaimii i
t »iosi«-. cncniii caunnts com*: i
i eciD; IODIII; atistRsc; anus; t
I snwrtusj siimt; SOBIM; suirns; i
1 IlllOIOt; ZIK I
1 1
1 t t«lm oe «orl4 llt«nt«x« em th« 1 J«akl», D.I.
1 >ee«nl*tta« ud blocoic«tntl« of 1 1979
1 l»l«ct»d taxle tne* ««l»l» IB ta«»m | H»-«00/»-79-Ot9, 1*4
1 k«lr »»J Bills ail otkcr iiiiillai | pp.
1 *ilr, f«. 1*11 «, diva ui hoofs. 1
1 1»b»l«t«a br 9io«npkie irii, I
1 «»b1«ct», ••>. *9«, izpocuti i
I qtillnt. aiilTMS la ppi. and 1
1 nthorltT fen ons 400 r«f«mno*>. 1
1 1
I mica: mstin.ii; cum; ctmu i
I tmici; mien; nom cm; in i
1 TJILltO; SODII 1ISIIC1; SonBClST 1
i »si«: uiiro nteDOB! TOITID srms; (
1 IIII; »IIS; 1STXCT; 1ITIBOII; I
1 mmc; Knot; cums; cBicnm; i
l cosiiT; CC??H: HID: mem: I
1 HCMl: SE1I1IBH: til; TllUXOB; tlB |
I Kitmot: tiiau POCTUTIOIS: i
1 BioicctmiKio*: sioiiDiciioas: HID i
1 POtLOTIOl: POPOLITIOI IXPOSOBI; »»TIS I
1 {CtlDTIOI; T11C1 nSKSRS) IK US t
1 1
1 1
I) 0.77 >g/9 | •) tipid Cltj. SO nlinifirois ar«a, | Ho««. B.
M as. 3 og/g | uMltlT « loithlr •iipllaf. «-2l «k« 1 147*
1 t) tip 14 cur, 3D, •wily «aipllng. $ I irchlrM of
1 «*s. DiaArnfC shupoa cooUlnlwj Si | EaTlconKatil H«»lth
1 t*a beim IM4. | 34(«):444-*4B
1 1
1 MiltbT blood doaors of Titleaa »q«», I
1 3o«th Dakota, Byoila^, lebraika, and I
I lotth Dakota. 1
1 1
1 sn.taii»: BICOI; nil; aim; i
t ceiPuitifE miamois: sons; SOOIB i
1 IITOTl; 10B1B K1KOTI; (IB11SH: |
1 1TCBIBS |
-.-I.. 1
a) 1.8 » or - 1.6 t » ««i«s | Tnkava, a.
og/g (»«t »t) | i) Teaalia | SninU-Iasnaoto, H.
b| 2. 1 • or - 1.« 1 | smaao. K.
ag/g (vit »t) I fioi a dtoop of 61 autopsies, | Terai, I.
1 lorsnslc aedlcal •zaalnatioai, Jap». I 1180
1 til«s, naa age *O.K yr. males, | irckiTes of
1 Man age 37.4 yi- 1 Envltomeottl ^aoltii
1 1 3S(1):3«-*4
1 1JICI mums; IDTorsiIS; J»»; |
1 itOBina: issMit; CJDKOB: COBUT; i
1 cnonint: cottttt itot: BEICOST; i
1 HDIO»; RiGKSItlB; BUCaVISB; |
1 tiBiBRH: inmon; scixoioi; t
i siimni; IITMIOB; TIUDIUI; ZIBC; i
1 6CIO; 5BOBIII: UTEB; KIDHEIS; |
1 C1SIBBD1: CflEBBllOR: BfaBT; II1ISCLZS; I
1 fllCVHS: SPIES! : lOKS; lOBTa; I
< tniis-, coifiHTin miaiTions; sis; i
1 TCREI5IC njDICIII |
1 1
(••XT P»6I) " 	
                                                                                                                                                                                       CO

-------
Selenlna
7782-»9-2
St
»tl 78.96. HP 170-217 C.  B» 685 C.  TP 1  aa Bg at 356 C.  10  •• Hg at  »29  C
txssnz


•M7
Heart













•448
Kidney










SXPOSOBB SO


Ingestion


































•M9
Kidney






















••50
(Uney




































ngestion











alUTtlCU.
BB»SOD

SC














11



















m



































IDBBEB
OF CASSS

1














a) 19
b| 3


















•I *
) 9
ct 12

































11IGB


a) lot given
b) pot given













a) O.SO-*.* »g/g (vet vt
b) 0.87-1.3 19/9 (vet vt


















a) 0.37-1.03 ng/g
) 0.31-2. 12 ng/g
) 0.25-0.71 Bg/g
•at vt




















Bot given
lot given










•III | GZBIIU, IBFOIB1TIOB
1
1
a) 251.2 ppb | a) Se IX, IT
b) 81.5 ppb | r) Se TI
Fresh vt j Igtopsies
1
I Canadian Indian, northvest Ontario
1
I PISBES; FOOD COBTlBIElTIOB:
I lIBBSTtlll ICIIOTIOB; POPOiHIOI
I 1IPOSDBB; BVBlt aI»S; ORBal lillS;
| IITBB POllOTIOB; BBBCOBIi BEBCOBT
| CIGailC COBPCOtDS: SELEIIffB; BBIH;
| MIKT; KIOIITS: UTZB; PUCERl;
I sum: cinci; IOTOPSIES
1
1
a) 1.6 » or - 1.0 I a) Rales
ag/g (vet vt) 1 t) Fenales
b) 1. 1 » or - 0.22 |
ag/g (vet vt) I Peon a gronp of 61 aatopsies.
I forensic nedical exaainatloas, Japan
j Bales, aean age ao.c yr. Finales,
j tean aoe 37. a yr.
1
| TBICt ILIBIRS; aOMPSIZS; J1PII;
| 11CBIIIH; 1BSSBIC; C1DBIDB; COBUT;
| CBBCBIHII: CCPPSB; IIOI; REBCDBT;
| IIEIOH: IISBISIOB: B1BG1IESE;
| BOP.IDIDR; IBTIBOR: SCHDIOB;
| 3IIMT9B; TIUIXOH: TilaDIOSi ZIBC;
| C01E; BBOBIBt; IITEB: KIDBBIS:
| CBBEBBUB; CEISBBtLOB; B31BT; BOSCXBS;
I tiiCBBiS: spun; loiss; IOBII;
| 9ITUS; COBPIB1IITE ITIIOITIOIS; SIX;
| FCBIISIC BItlCIBE
1
|
) 0.70 09/9 | a) Controls
) 0.52 ng/g 1 t) Vorker qroop I
) 0.33 ag/g I c) Barker gronp n
let »t |
edians | Eaccased refinery and snelter
| aorkers, ages 55-76 yr, exposed to
I heavy netals 1-3 decades, fine
1 bctveen retirenent and death 0-1.5 yr
I in group X and 2-19 yr, gronp II.
I centrals, ages »3-72 yr, who lived 50
1 k« fron the factory. Sveden.
1
| SflDBB; CtOaTERS; KIDBRS; tITXBi
| HISS; COBPU1TITB ETlIDtTIOBS;
| IBDOSTBIII BTEIFBB; BZISOBEBZIT
| IRBODS: 1RIBOBT: USEBTC; UOBIDB:
| CXSm; CBBOBTVB; CCBilT; COPPEB;
| CCLD; HOB; 11BTB1EOB: LE1D;
| niGlBSSI: BEBOTIT: BOlTBDEBtm;
I FBOSFHOBDS: SUBIDIVB: SClBDIDi;
I snsBivi: suns; TIB; TUBGSTEI;
| IIHC: B111TB B1Z1B9S; IIDUSIBIK
I PIIITS; SBEITESS; TBlLBBlnB
1
10*3.* ppb | a) Se II, IT
707.8 ppb | t) Se TI
esh vt j latopsiea
1
| Canadian Indian, nortbvest Ontario
| lISRtS: FOOD CORHIIITIOI:
| IBDBSTSItl IOUOTIOI: POPBlltlOl
| ItPOSDBf; BB»L UB1S; HBBM UlaS;
1 inn POLUTCTOI: micisi; B»cnn
| C151ITC COStCDIBS; SILMIOS; Bllll;
1 niirt; Kinitts-. iiTt*; VLicxna:
| STlBtl: CHltl; MTOFSI1S
1
BZFEBBICI


Cnppon, C.J.
Snith, J.C.
1981
Journal of analytical
Toxicology 5:90-98










ynkava, R.
Snmki-yasanoto, fl.
Inano, H.
Teral, B.
1980
irchiTes of
Eavironnental Health
35 (1) :36— aa












Ernie, o.
Bordberg, G.
•ester. P.O.
1980
Science of the Total
Environnent 16:13-35


















appon, C.J.
nita, J.C.
981
onraal of analytical
oiieology 5:90-98







litn ttsi)
                                                                                                                                                                                       N3

-------
77SJ-»9-2
51
Itf 7».»«. n 179-217 c, B> 665 C, V?  I u  Eg  at 3S« C,  19 mm Rg «t 429 C
                                                                                      fCOBTIIBID)
MSSJI

MSI


















aa52
























M53
ll»ar










irosnE toni













































Imgwtlam











IM1TTICU
gnaw
n


















»
























ec











n»n
or cuss
7
7

















a) ft
b) 9
O 11






















1











IIBSI

1.2-C.2 »»/g (nt *t|
0.15-3.4 ag/g (nt it)

















) O.IH-O.at aoyg
b) 0.12-0.35 »g/g
O 0.11-0.23 ng/a,
'•t wt





















a) »ot gim
b) lot glT«>










•BIB | GtEtEll IBPOH1TIOB
1
2.7 * or - ».i I >•!«
g/g (mt «t) 1
1.9 * or - 0.98 1 MOB a groap of *1 aatopaias.
g/g (»«t «t) 1 fatmile aatical •laaiutiami, Japan.
I Bfllctf* Baan aga 40«C yir« Ta>alo»
j a«ai age 37.* TT.
t
1 met ZIEBBBTS; inoMiES; JIPIB;
t IHBIIBR: 1BSEBIC; ciouina: coBUt:
| CB1CSIOS; CCJJIS! 1MB- BlgCOET:
^ iBtni; MSKSIBB; IM«HISB;
I lotmm; IITIBOBI: SCIBBIIH:
| EtlEBlV!!; 711aBlQS$ T&BlftlQB; ZIBC;
| CCIB; BBODIBE; UTEt: nDBBTS;
| CltmUS; CtBEBHUBi BUB1: BISCtESi
i fiBcaus: mm: tnies; torn:
1 llt»13: COBtlBlTITB CTllOlTICIS; SEIi
| rCBEISIC BtCICIEE
1
1 0.19 gg/g 1 a) Coatrols
1 0.20 ag/g I b» lerkcr «TS; SBEITEIS: TtlmSIBB
1
1
a) 269.7 ppb 1 a) S« It. n
b} 176.1 ppb | t) 5* TI
Tna% «t | litopci**
t
I Ciaadlaa IrnJlan, oortivaiat Ontario
| fISBBSJ rCOD COVTMIBItlO*!
I 11IHSTH1I JOUnTIOB; WPOUTIOB
I IIMSOSE; BQBU ItBIS; DBBH 1BB1S;
1 IIIZB rotimoB: iticnn: BEICHBT
I CESIBTC coifcorM: snniiHi BUKB;
| BUR; XIDIItS; LIVEB; FL1CITII:
i SHIEE; ctBitt: inopsiEa
BEFEEEBCt

Tnkaia, B.
Sazvki-Iaaaaoto, I.
lauo, I.
Tarai. B.
994
rchiras of
^nixouental Evaltb
35(1):3*-M











ElOB*. D.
loclkerg. G.
(•star. P.O.
19SO
Sclaaec of the Total
EnvicOBaemt 16t13-35'



















Cappoa. C.J.
Salth, J.C.
1981
Joarnal of Inalytical
Toiicology 5:90-98







ittn «*eB)

-------
s«l«nlu«
7782-49-2
Se
l» 79.96,
           BP 170-217 C. BP C«5 C. T*  1  aa  Bg  at  3W C.  10 •• Bg at 4.29 C
                                                                                      (COITII9ID)
TISSB!
4454
lung
4455
4458
Basel*
I exposing som
1



IBltTTICU
H5THOD
n
•i
i
•OHBIl
or cists
•2
a) «
b) 13
0 23
C
4
IUU
0.52-15 ng/g (««t «t|
a) 0.044-0.22 njyj
b) 0.068-1.56 ng/g
e) 0.00 10-0. 301 ng/g
»et »t
0.67-3.3 ng/g (mt vtl
0.57-2.2 »g/g (««t «t|
1MB | SIIIBII. IBrOSBMIOI I tXrCECBCB
1 1
1 _J._._ f
1 1
7.» + or - 10 aa/g | rtaales j Takam. I.
(Mt «) | t sanU-Tanaoto. B.
I Icoa a eroap of C1 aatopales, | leaao, E.
1 forensic aedical elimination*. Japan, i teral, B.
1 Balm. aeai age 40.* rr. resales. I USD
( HI* ag* 37.4 rr. 1 IrchlTM ot
1 I >CYironB«ntal Health
l mcx zvBBZws: IBTOPSISSJ JIPIE; I 35(i):3«-»»
1 iiBBiBis; IISZBIC; CUBIVB; COBU.T: i
I CBIOTIiT*; CCPPZB; 1MB; Bncntr: I
( ItCIOB; BlSHSin: BHUIfSI; 1
l IIUDIBB: aniBOBT; SCMDIDB; i
| JltlBIia; TIUBIW: VIMBIVB; ZIK: I
| eOtDj SBOBTIE; UTEB; KID11TS; I
| C!«lBHJ 55-76 rr, eipoaed to 1 EnTironMot 14:13-35
< aea«T aetala 1-3 decades. Ttae (
j cetMea r«tlr»a«ot aal deatt 0-1.5 yr 1
1 ii groop I aid 2-15 jr, gcoaf II. |
1 controls, ages 43-72 TC, vho Uwd 50 I
j k« froa the factory. Sveaei. 1
1 1
1 iftiEt; cuiims: Kitastss IITEB: i
1 loies: coB»iM?in mintiois: i
| JIBBSIBI»t BISIZBE: niSOSEBIBT I
| I1TB09S; inlBOITi IBS IIIC : CIDBIHB; 1
1 cisiDS: craoBina; COSHT; COFPSC i
| CO ID: HOB; tlBTBUOt; LEIB; (
| tllGlHSS: BSECfflT: BOlTBOtlDB: 1
1 tsospBOKBs: uraiDiUB; scimims i
1 siiiiini; aims; TIB; TDBGSTSS; i
t line: aiaitB Biiugs: IIDOSTBIU i
| IIliTS: SMIIEBS; TJLIDBIDB |
1 1
2.1 * oc - 1.1 fa} Bales I Ynka«a, B.
g/g (««t ot) 1 t) reaales | SnicU-Tanaoto. f.
1.1 * or - 0.76 I I llano, K.
/g (net wt) t Troa a groop of 61 aatopslea. I Terai, a.
| forensic ae4ieal exaaiaatioas, Japan. ( 1»eo
1 Rales, lean age 40.6 rr. fvaeles, 1 Ircbives of
I lean ag* 37.4 rr. | EtTlronaantal Health
1 1 35(1):3«-44
| 151CE nSBIRS; 1QTOPSIK; J»1B; 1
l utBiivB; nsmc: CIOBIOB; COBUT; i
I CtBCBIIl: COPPZE; HOB; HEBCOST; 1
| IBtlTV: B16BESIVB; B1BS1BISI; 1
1 I»*IBIBS: innoir: sciioioi; i
| 3HZBIH1; TI1UIOB; TtBkDIOB; ZIBC: 1
I eciB: B«o«iii: IITH: KIDBEIS; i
I cfimoi: ciaraiiiog; ajisi; RVSCISS; I
l tincssis: spiral: tnvss; tent: I
| BrTILI-. COBPUtTITE CTUOJTIO1S; SSI; |
( fCJIKIC BZBKItE 1
1 1
                                                                                                                                                                                          NJ
                                                                                                                                                                                          vj

-------
Seleala*
7702-W-2
S«
lt» 7B.9S, H 170-217 C,  BP 685 C. TP 1 •• Hg at 354 C. 10 •• Bg at «9 C
IISSBB
**57
nil
MSJ
Pancreas
M59
Tltceat*
»»so
Spinal
cord
POSIWE MOII


Ingest Ion

iuiRicu
mioD

i
..
ac
1
1UBBES
r cisss
»
(1
C
> 3
1
a» 1
b) 3
tUSE
lot gireo
Bot glMn
1 1.1-3.S og/q (mt vtl
1 0.»7-1.6 ag/g (vet «t)
a) 23. 3- SO. 1 ppb
b) 6. 3-16. « ppb
a| lot applicable
b) 53.0-180.2 og/g
RBII i sunn. iBTottiTioi i BBrnncB
1 l
1 1
0. 18 * oc - 0.59 | •} Cosea 1 Kaubrocki. E.I.
ppa | r) Bea | Kanabroeki. J.li
0.58 » or - 0.27 | left thaab I Greco, J.
pa | llso re»iew4; kao» levels of 30 t Kaplaa, E.
FT (t I ctker eleieat* 1 Oestac. I.T.
1 1 Br», s.s.
| Bailtkr 20-6C rr oiaa { Gaatafson, r.S.
I 1 1*1800, D.I.
1 »t TOTS; SEX; mis; sstnij ILDRHOH; i iioare, c.i.
I UTiBowt; tusnic: IUIDH; CIDSKTR; i 1979
I CUCin; Cisni: CBBOnni; COBIVT; 1 Selavee of the Total
I CCPPE8; SIEHUItJB; SC1.0: Itoi; LE>0; I Enironaent 13:131-1*0
| IteiESini; BUSUESC; ICEKCOST; |
I IClTBIini; IICKEL; POTlSSIOa; |
I BOBioinH: siinni; smcoi; sima; i
| SOtlOI; STBOITXai; Til; TIHII08: |
I fii»ivB; UK; IIECOIHIB i
1 1
1 1
1 2.3 » or - 1.0 | «> Bales \ Tnkan, 8.
g/g (vet »t) I t) teaales I Snznki-Tasaaoto, R.
) 0.89 t or - 0.62 | 1 »aaao, K.
9/9 (vet vt) 1 tcoi a gro»p of C1 aitopsies, I lerai, R.
j forensic aedlcal exaataatloas, Japan. I 1980
1 (alee, aean age »0. S jc. feaales, j trckiTes of
1 teaa *ry «t | lentral bora tiasae, avtopsf I 1979
| lo detectable Se la 6 other patients j laaals of Seorologj
I aa4 9 controls | 6(l)t21-2»
1 1
1 1! TI oU an dial of progressive 1
1 avacalar dlctcopkr- "7-67 TI old 1
| centrals, dlcl froa chronic ceual \
1 failaxe, breast careiaoaa. and I
I ceroitaTT artcrr diseases. |
1 1
I 1'TIS; 1DV1TS; iOTOPSISS; |
1 1IOSOHUSCD1H DISEISIS; SPIBM. COST); |
| ElOlCdinilTlOW; ClLCfOIi COPPEB; I
I TBCI; litt: RHGtRZStt HETILS-. 1
I sitirriR: zitc i
i i
(HIT *IBB)

-------
TTM-W-2
3*
at« TS.4C.
              1TO-2IT C. Bf «*5 C. TP 1 •• S? «t 3S« C. 10 M Bg at »29 C
                                                                                     CCOBTtlVtD)
TISSBB
•Ml
SplMB
M«2
Splwa
MS 3
vrica
««<•
Brine
MSS
9rlm«
EivosnE ion

lBf*StlOB
BgeatiOB


IIllRICll
BKBOD
H
ec
us
l«arl«i. 1 T«r»l, S,
1 fOTCBcle »»alcal extilMttoa*, Jap«o. | 1980
I >*!«*, M*n tcj« 40. < tr. F«ul«a. I Jrchliei of
| MM (TC 37.* TT. 1 ZBTlCOBMBttl B«»lth
| I 35(1):3C-M
1 ttice H.BHMIS: AOTOFSIBS: Jirii: i
I unnirav; »»St«IC; C»»HIt)»; COBIXT; I
I cERonma: comi: itoi: IEICVET; i
I JIDIOI: iieKsniB; uientsi; i
1 imlDiuB: utisowT: SCIPDIUB: i
| StlEtXH; TIH HOB; nUBIDB: II»C: |
I SOID: BlOIIlIi 1ITH; KIDIIIS: |
I ctmtvts cEimun; HIM; HBSCISS,- i
| EllCIItS; SPIBII! LVKSi 10IT1: I
| BIT IIS: COSP1BITITB BT*L(TlTIC«Sl SIX: I
| fCRKSTC HIDICin 1
1 1
1 1
•I 2«6.6 ppb | «l S« II. IT | C*ppOB. C.J.
b) 1*2.4 ppb ( t) Si H | Slltk, J.C.
rresh it | I«top«le» I 1»81
1 I Jcara«l of laalytlcal
I ca>i4i*a IndUa, Boithnest Oitatio 1 Toiicology 5:90-98
1 1
| IISBIS; FOOg COIIISIHTIOI; |
I TiDnstaiu pauonoi; MPOIITIOI i
I IlrOSBlB; DIBU 1BMS: ITFBJ1 1BE1S: I
i mis voiinioi; NICVBT: SBBCOBT i
I oi0iiic coifcttiDS; stimat; BB«»; i
I BUM: KIDMTS; 1ITBI; PUCBBT1; I
I SEXin; Ciiiti: imopsiis i
1 1
79.21 + or - «». 12 I §«sld»ots •«!»» «it«r ftoi nils with | talmtlte, J.I.
g/1 I :e-1800 a? S«/l I Kt*4t R.K.
( 1 Hang, P-l)
1 Iliac, TS | Sckloektcc, B.
1 1 "9°
I I1B BEIICO: BLOOB; B1IB; DBIBE; I Journal of loiloolo^f
I 9ET1L3] SH.IITHB: BBUtUG «1TEB; | ana laTlcoaBeatal
| IIZTMS5: POPOHTIO* nPOSDBt | Health 6:731-736
1 1
t 1
2.3 » or - 8.21 ag/1 I I Gaahehaa. 1.
| | CbMboi. P.
j Bataial. BOB-oecipatieaallT «i posed I 1980
I 11-77 yr old*, tjom. Fiuic*. I Clinlcil Chemistry
| I 26 (9>: 1772-127*
1 sztmni: REIIIS; rsucs; ami: i
( BMSntlBfT BET BOSS |
i i
1 1
063 »j/»l 1 Bapid City, SO, Ml«aH«lo«i aim. I Hon. R.
1 nmklr or aorthly saiplUa. *-2« i>k>. I 1«74
i i archives of
I Maltky blood doBOrs of vatloos age*. 1 BaviroiaeBtal H««ltl
t Seitk Dakota, lyoalao, labrarta, and I 3*|«) :**»-»«8
t lotti Dakota. I
1 1
t sniEToi: BiooD; mil: ram: i
I CCH»BaTITE EVlLVktlOBSi SOUS; SOOTH 1
I C1IOTI; 101TB KlIOTl: ffiBBtSIa: I
i iionis i
1 1
                                                                                                                                                                                        00

-------
JSJ-W-2
cz-i«-r2-si
ft 96.15
TISSUE
•MS
Breath

EtPOSintE 8OBTE


1U1TTIC1L
IETBOD
re/us

•men
or c»sis
8

UK!
'
1.2-UO.O ug/lr

mi
28.9 vg/hr
	 	
SIIES1L nmiUVXOI
_
Coapoaii related to noraal
eetabollSB. «o other Oataila glvea
lealthT allltary *a4 ciilliaB
eiploTees. U.S. ilr Force School of
lerospac* l«4icla«, ages 23-*7 jr. 3
IIKSISS: CBtOKIIaTEB BIBIOCUBOBS:
CEIfltIM OtSlKC COIPOMDS;
cnoBoniimsi nvcnn coiponiits;
iBHTi: itcosots: tins: IDOITS
miiEici
C oak la. J.P.
Caap, B.J.
Belck. B.E.
1975
IrcKlves of
iBTiraaaeatal Health
30 (2): 294-295

!2Q-5«-«
C3-l«-?-S
«1 92.20
TISSUE


SKOSOBS BOOT! I
1


1ULRIC1L
IETBOD
ec/is

imisB
07 CaSXS


BaBGB |
1
lot detect «a-5. 2 ag/kr

HEli |
1
0.7 aj/hr

eiHBll UTODUIOl
CaipoBBi froi BikBOBB origin, lo
ether details 
-------
Silicon
7MO-21-3
SI
»tW 28.086, IIP into C, BP 2600 C. TP 1  » H, at 172« C
                                                                                      (COHTIIUED)
TISSUE

• •TO
si ir

















««7l
Rltaer






HT2
linr



EIPOSVSE SODTl




















Injection







n lection




1
1
1
1
I
1
M7J | Injection
l»9 I






AULTTICll
HETBCD



















US







us










us







IUHBEB
OF C1SZS



















1







1










1







JUCI




















lot applicable







at applicable










at applicable







BZH




















120 «g*







5* «g<










*000 «q»







SEISE1L IlfOSBJIIOB

P«lie». :• reprasentatirs
FC«-*nslTSi3 treatients are
tabulated. I be leasibilitr of a
tolistic, na-irasa palter foe hair
analysia is catlinea and snpportea.
BITIH; TB1CI ELMERS: HUB:
mSTBJUl: RIlSVBEgilT SETBODS;
eiTJIS; tSOTlHS; COBP1E1IITI
ITAlOaTIOIS; »1UBI»OI1: 1IIIBOIIT;
1ISEIIC: BtEIDA; BBOIIIE; ClDHinS:
ciicwfi: ceicBiRE; cmtoanju: COEIIT;
CCPPBl; 5HIIUH; CTSBIHOB: GOtD;
icoiiE: iBoi: Linauvts lEic;
HSIESI7I; auetnsE: OJRCIIBI;
eCITBDElUB; IICKHI.; PaOSPHOEOS:
ECIISSTOS: BBBItltll; SILEIIVi:
Silicon; SIITEE; SotUBS; SIBOHTItTB;
SD1FDE; III; TIUKDH; THIGSTEt;
Hie; zucoiitm


Caucasian, a«< »0 yr.

Cifeoli it lanqs
ivies; Bain: HOOTS: LIVES; BLOOO
SIBII; siticci; CISI aisrosirs;
IOTOPSIES


Caucasian, 890 40 re*

Iitali in Hag*

laiGS; BBIII; KIDRTS; 11 YES: BtOOO
siBOB: sincoi: cisi BISTOBIES;
laiopsits




Clicuini, >9« *0 re.

liboli ic lanji
iqiGS; BBIII; KIIIETS; LITIB; B10OD
SZEIII: siiicci: cisx BISTOEIES;
leiopsrts
BEfSBESCS

CbUtleborongh, G.
1»SO
Science of the Total
Emironient 11:53-75















Solow>na« E.T.
Jones, O.K.
1»7S
Journal of Forensic
Sciences 20(1): HI- 199



SOlOKIK, E.T.
Jones, J. It.
UTS
Journal of Forensic
Scie«cet 20(11:191-199






Soloions, I.T.
Jonea, J. K.
1975
Joucaal of Forensic
ciences 20(11:191-199



                                                                                                                                                                                          NJ
                                                                                                                                                                                          00
                                                                                                                                                                                          o

-------
7MO-22-*
at! 107.86S, IP 9M.5 C,  BP 2000 C. TP I n Bg at 1310 C,  10  •• 19 at 15*0 C
TlSSIt
«*T*
Mir
»»75
Kiaaer
•*7«
Lint
MSVIS IOBIB



iMimcii
BETBOO

I
»
*OBBH
r cuts

> 8
1 21
•) «
« w
IIISE

J < 0. 005-0. 0»S a«/g
I < 0.005-0.18 ag/g
et «t
a) < 0.005-0.032 »4/«
b) < 0.005-0.33 oj/-j
••t rt
iul i CEIHII iiroiamoi i BBFEBBBCE
\ '
| levie*. 2* r«preMBt«ti»e 1 Caittlebocoagfc, 6.
| pre-aaaly>i* treataeata are 1 1980
| tabalated. the feasibility of » t Science of the Total
1 Bcltetlc, no-task policy for hair t Enilronaeat 1»:S3-7S
I aaalysia la eatliaed aad supported. I
I (met; mci ncnrts; Bin; i
I lISTItlll; niSIUIEd BETBOBS: I
I EttaLS; ttotmsi coariiiTin I
I Mimitiois-. limnm; H1IBOVI; 1
I nsnic; Binoa; Btomi; CIDHTUE: i
t ciicrjs; cnains cnciioi: conn: t
I ccrrn; siLtnrn; SEsaiiroe; SOIB: i
I icons; laof: UITKHDB: LUC: I
I a»oi*sio»: uiemsi; SBBCOSI: *
| ICITBDnOBi BICKBLi taOSPBOlOS; 1
| CCtlSSntl; BTOtOIUS: SELIItlH: t
I siircoi; sit TIB; SODIOB; stiomoi: i
I sum: m; winna; monti; i
1 UK; nicciiot I
i "
1 1
) lot give* 1 a) Controls 1 Brane, D.
1 lot giTeo I t) Workers, qroipa I *a4 II 1 lordberq. G.
| I tetter, t.O.
I taoeasei tefineir u< aeeltai 1 1980
( wckec*, aqea 55-76 rr. expoael to 1 Science of tie Total
1 l«»Tf aetal* 1-1 tecalea. tin t Inilroieent 16:13-35
1 t*t«eea retinaeat and death 0-1.S JT |
I ia oroap I ««fl 2-19 Tt, qroap II. I
I Ccatrota. aq«* «3-72 rr. «ao litei SO 1
1 ka free the factory. Svedea. I
| SIMM: CIDIKBS; IIDBCTS; LITJ8; |
1 totss-. coitiuTiTi mniTioss; i
I IIDJSTBIlt 1T6IEII; B!»SOBlBtHT 1
| ttTBODS; HTlSOIt: «BSB«IC: CIDHUJB: |
I.CISIOB: CBEOBIOB: coBiLT: coppu: I
1 coin: iici; unsiiOB: L»O: i
1 iHSaKSt: incnn: SOITBDIIOB; t
| EtOsrHOIOS; NBIDIOI: SCHDIOB; |
| StlEflVl; S11T?R; TI«; TOUGSTM: I
| tllC: BBalTI SillBDS; IIDgSTlIll 1
t mvts; s>itnns; niLotitii i
1 ..._!.__
1 1
a) tot gi»ea | a> coatrol* 1 Brae. D.
b) lot giTea I t] lorkera, gcovps I and XI 1 tordberg. G.
| I (ester, ?.Q.
I te
-------
   Itt 107.SSB. n* f*0.5 C. B* 2000 C, TO  1 » Bg at 1310 C.  10 •• Bg at  1S<0 C
                                                                                        (cormtiD)
IISSVB

J.S




















MTt
•nil
















ixrosvBB BOUT








































ilainxcil
BETBOD
n




















11

















BDBE-SS
or cisss
at 8
b) 20




















•1 9
b) 11
















ur«i

a) < O.OOS-O.OCO ng/4
b) < 0.005-0.02* ig/g
net «t



















a| lot given
b) lot given
















BUB 1 eillBaL ItFOtmiOB
J
a) lot given I «) Controls
b) lot given I r) farters, eroepn I and II
1
I Deceased refleerr and snelter
j sorters, ages 55-7« rr, exposed to
I k«a»T netals 1-3 decades, tine
1 tatveen retlrenest and death 0—1.5 rr
1 li goarp I aid 2-19 vr. groip II.
I Centrals, iges *3-72 it, >no lived 50
| ki fcoi the factory. Sreden.
1
| SlIDEI; CIBtTBtS; KIDIBTSl IITBI:
I uies; coapuifin mtnnais:
I IIEDSTIIU BT.8XSII: BBISmBttn
I BITBOCSi aRIBOII; IBSSRCJ C1MIU8;
1 cismis CBBOBing; COBIIT; COIPEB:
I COID; HOI: I1BTBUOB: 1I1B:
I IlietlCSl; BItCOBT; WIT8DIITO:
I iBospBoins; iBBiDioB: sciinimi:
| SmirtH; SIITBI; TIB; TOISSTBI:
I IltCi BU1TB BlZalDS; IIDOSTIIU
| PI11TS; SBBMEBSt tEIlOIIOB
1
1} 0.7* « at - 0.7* | •) lonei
pps f t| Ben
b) 0.3* 4 or - 0.20 I left thnnb
ppn I ll*o revleved: knosn level* of 30
Dry «t | ether ilenent*
1
1 Beilthf 20-60 yr olds
1
I irtjiTS; sn; mis; ESTIEI; itOHiinB!
1 iniaowT: iisEtic; BititrB; ciBsiH:
| CllCItU; CISTO8; CBBOBZOB. COEllT;
| CQPVBS; 6ESB1H1IB: GOtD: IBOI; IEAI>{
| BISIISPJB- BIBMBESB; SEBCOBT;
1 catiBDitVBi ncKiL; ponssiaa:
| IBBIDlaB: SEIBBItB; SItlCOIJ SItTES;
| SCCIOB: STBOITIIIBi Til; TIT1II09;
| TIIIOHJB: UK: ZIICOIIDB
« 1
EEFBIEICE

Brane, B.
lordberg. 6.
(ester, t.O.
1980
Selene* of the Total
Envlronnent 16*13—35
















Ranibroctl, E.I.
Kanabroeki, J.I.
Greco, J.
Kaplan, E.
Oeater. T.T.
Brae, S.S.
Gestafson. P.S.
VelsOBy 9.8.
Hoore, C.E.
1971
Science of the total
Bnrlronaent 13:131-1*0






                                                                                                                                                                                           NJ
                                                                                                                                                                                           oo
7««0-23-S
la
Itt 22.»am. tt 97.K C, BF 881.4 C, TP 1 •• B« at MO C, 10 •• Ig at S«< C
TISSBJ
««7*
Slool,
serei













t
1
t
»
BIPOSBK MBIE
















1
\
\
1
iiunicu
rnnm
us















\
\
\
t
ItlMXt
OF CASBS
» 260
b) 260














1

1
»-
MBSB
a) lot gitrei
b) lot girea















1
t
i
Bill
1*0.60 « or - 1.W
•eq/l
b) 13B.5S » or - 0.77
•eo/1












1
1
t
«
eBIIML IlrOBMTIOl
•) laisas cltj, ts, Uri-iiter mi
b) taasas Cltr. BO, so(t-«at«r area

IS and BO resident! eatehed for age
(•em aq« 37 and 37.7 T?| , >ez.
liigtn of residence, iiritil and
•conaile states, occupation, inber
cf ehtlim, stoking habits, ht, ¥t.
In hard-water area, slenif Icaat
liczease In hypertension, BCG
•bnocnalltles, ind irperarlceiia.
(lists; H1SSC0H: itottss
C»CIOT1SC«1*I OI3B1S1S:
mirriisiai: noon ssjnn:
ccBfiiaTlTi CTH.OITIOIS: CIMIOS:
cncii«s cBiciitiB: inBiaB:
ii«»sm: IMSPBOIOOS: TOUSSIW:
I sotimj me; sioiccn-nrntioi;
t ntncna »M«
\
nrEBicB
Blerabm, H.L.
nelaehsan. 1. 1
Dunn, J.
•mold, J.
1975
Lancet
1(191«):1008-1016











1
1

-------
So41»
7MO-23-S
la
lt» 22.1*977, n 97.82 C, BP 881.4 C, TP  1 mm gg at MO C. 10 » Sq «t  5M C
                                                                                      (COsTIIVSO)
trssnB


•MO
Balr










_i_
air



















M«2
Balr












irosots tout B

















































iBiinicit
RSTBOD

US
































•1













BDBBBB
OP casts

31
22































a) 23
b) 14
0 »2
4) 1*
•) 26
O »0









B1BSB


Bot gi»«n
lot given































a) 3-19* aq/q
b) <7-»0 noyo;
c) <7-1»9 aq/q
d) 12-196 ««•/«
•t <7-9» aq/q
I) <7-«96 «g/«









B«B | GBIIfU IBPOtBlTICB

1
1
1(37 pps | a) leaning disabled
919 ppa | t) Controls
1
1 learning disabled and soraal 3rd aad
1 «tk grade stndemts 1m Canada.
1
1 ciicna; siGissxm; POTISSIOB;
1 SCDIOS; CUB MB; COB11T; COPPIB;
1 IFCI: LBID: UB«iiBSB; IIBC:
1 cnoBtna: itiBiBB; Bttcmt; anus;
1 BUI: caxiom: ciiim
1
1
1 Beyie«. 2* representati**
1 yea— analysis trttatnvnts ara
1 tatnlated. TV* feasibility of a
1 nelistle. no-*ask policy tot halt
1 analysis is outlined and supported.
1
1 iivin; TBici stiazns: am;
l issniLii: BUSDIBBBIT BBTBOES;
I mils: Ptornis; cowitiTin
I IlltOltlOBS: 11DBIIUB; iniBOIT;
1 nsnic; siHoa: BIOIIR; CUBIOR;
I CIICIDB; cairaiK; CBBOSIOB; COIUT;
I coppts: oiniuB: eEMinva; GOLD;
| ICBIll; IBOI; tlBTBlBVI: 1»I;
1 tisBssraa; BiaeiBssi: RSICIBT:
1 iciTBDBna: UCIIL; PSOSPHOSBS;
I IOTIS3I1S; BBBIBIBB: SJLIIKJS;
| SILICOI; SI1TBI; SOOIHI; SIBOBTCTa;
1 SHLP01; TIB; TITlHtlB; TOBG3TIB;
1 IIBC; flBCOBIOB
1
a) 3* «g/q I a) Bale costcols
b» 3 aq/q | k) Fenale controls
e) 1« »q/q | c) 111 centtols
d) W aq/g | dt Rale aaltiple sclerosis patients
e) 9 aq/g | «) Peaale saltiple sclerosis patients
f) 1* «q/q | f) 111 aaltlrle sclerosis patients
aedians \ Staple* fros 7 scalp sites in eack
t sablect.
I CIB1V1: ICtlllS: CBRSll niTCOS
1 StSTIH VISH3E5: BUS; llOBIBOa;
1 ciORiis: cucnR; CHIOBTH; COPPEB;
I SOU; IODIII; aiasiBBSB; aiTUS;
1 3tl!lT01; SItrEB; SOBIOB; S01POB;
I viiion*: UK
	 1
BBPE1EBCE


Fibl. B.C.
Carkes, B.
977
Science
198{*313):20*-206







chltUcboronqh, G.
1980
Science of the Total
Enrlronaant 1«:53-75

















Hyan, D.I.
lolxbeener. 1.
Sturt, D.C.
197«
Clinical Ckenlstry
2«(1t):1«9«-2000









                                                                                                                                                                                            NJ
                                                                                                                                                                                            00

-------
Strontium
7««0-2»-6
Sr
it! 87.62. at 357 C.  tt 1366 C.  TP ID « Bg at (48 C,  1 u Bg at T«0
TISSUE
««*3
Kir

















EIPOSORE BOOTS



















1I1LTTICU
ffiTHOD



















iron BIB
or CISES



















MISS



















Bill



















GKHBal IIFOSHHIOI
B«Tle». 24 repreaeatatiTe
Fr«-»B«lTSi« treataents are
tabalated. Tee feasibility of a
holistic, »-»ih policy for hair
aaalrsls is oat lined aad sapportea.
mm; TSICI ELIBIITS; HUB:
lOSTBUIl; IBlSOBIinT BKTBODS;
BITU.S; PBOTU1S-. COBtaUTITl
iTiinfiovs; itninnH: jmHoir;
usjrrc: BJBIOI; BBOHIMS; c»xira:
ciicni: cetcsiiB: craonoi; COBU.T:
CCPPBE; StlLIUB; GEESillOB; GOLD;
ICDUE; IBC1; IIRBHVI; IEIE;
BieiESIDI; MVGinSI: IBECIBIt
fciiBBHOB: HCEH: PHOSPHOBUS:
PCIISSIUS; ETOIOIDB; SEIBIIUB:
SIIICOIj SI1TEBJ SODIOB; SIBCrilBH;
SClf OR; III; TXTMim; TOUJSTEK;
fHC; ZIBCailSJB
SEFEBERCE
Chittleboioagh, «.
1930
Science of the Total
EnlcoDient 14:53-75















       re en
       «tbearl-
  101.1*, HP -3t C. »P M5-1M C, n 3».« ati tt 37«.« C
tissvi

«»a»
BIooJ,
•hole










MBS
Rrlie









EIJOSOBE BOUTI

Inhalation












Inhalation










IHITTICH
HETBOD
sc/ns












«c/«s










MOB BUI
OF CiSES
«

I










*










UltiS

a) lot giT«n
b) lot 9 Iran
c) Rot given










Vot gir«n










IEJLI

a) 0.« ng/ml
b) 0.92 » or - 0.26
ng/«l
c| 0.01 09/1!








-
2.12 * or - O.BO
•illiioles









etllUI UF09B1TI01

••) Initial lalae
t) peat, at 6 hr
e) Final valie, at »7 »r
Dcs« «as 90 pp«
a> anS a} estlnatel froa gcaph

Healthy Caucasian 2«-«« yr olds.
72.«-*0.7 kg.

•Off* odor, ilia eye Irritation, van
eeawtlon is face.
STTtmS; SICOO; tllUattOI: lOOLIS;
CITIf; HtTlBCirTES
»S hr lean eicretions o* aetabolites.
ian4ellc acid and phenTlglTOiilic
•eld. Dose «as to ppa.

Icaltay Caaeastaa 2***< rr olfla.
72. 6-90. T ka.

•Cff" odor, aild ojf Irritaltoo, wars
sensattoa in face.
StTtNES; BLOOD; TIH1HTIOI; IDVLTS;
UBIIE; HETIBCLTTES
BEJE5EHCE

B»a«r, J.c.
Icing, J.D.
Karbovskl, B.J.
Chenoveth, B. B.
HcCartj, t.P.
Brian, i.e.
1980
Tozicology and Applied
tharaacologr 53:5a-6J




Baaaer, J.c.
Tonag, J.D.
Rarbovskl, E.J.
Cnenoveth, B.B.
BcCartT, l.P.
Braan, I.B.
1980
Toilcology and Jppliei
Phuraacologr 53:S«-63


                                                                                                                                                                                      to
                                                                                                                                                                                      00
                                                                                                                                                                                      .p-

-------
 Siltli*,  ntlrt propTl <• Cl)
 Prof tarn,  1- fMthftklo)- f» CD
 3!77-f5-»
et-Bio-s
01 90.1*.  IF -113  C.  B» 95.5» C
TISSttE
•age
Breath


EXPOStTBB MOTE



tniTTIClL
SEtBBO
8C-SS


or CUBS
"
S« (387
naplas)


BMSS
lot giv«a


sui
SaoMtric


G1IERH ZVT0194TIDV
B«aanr*l at 25 C a*4 7«0 aa •«
11. 5t oecmtme*
IOMC afl appn oa*-Slgaa Halts 0.39
*«4 5.1 mayl
ecaltkTi. 1B-3S TC old. nonaMlting,
CHcacjo, II. iiqidly controlled
tipatlacntal caaUtiou.
mug; 11COHLS; IlLItOIS; 1DUUS;
ceitnrnun BrosocfiBOis; TOIITILS
CESIE1C COEICHBOS: BHI.TH aiZlBCS;
IimntlO": aiTlEOllSa; antBOLRES;
IOPBI1TTOI TIPOSOM: DEBIE *BB*S
taaeK*
BEHBMH, 6.B.
O'Vaill, B.j.
W7S
Joamal of laalTtleal
Toiicologj 3:225-23*


 si lew
 n
 s
     32.06«,
                      C, fit abort *»».& C
1ISSVX

M87
BrtMlli








*.*B8
Uttlr
















»••»
Balr









:IPOSOB1 BOVTE

Inhulitlon






































aiunmt
HETBOB
PIXE



























n










BOBSIE
or CUES
1



























a] *2
b) 10









jHGt ~~

lot ql¥«B



























a) 2.T7-3.99*
b> 2.46-3.73T









am |
1
S.9 n«



























a) 3,'sr
b) 3.23'
BleUaas








GEIH1I IIFOiaiTIOI

« 1 saaplaS it rat* of 1 I/ail. 2-10
•In aftac baralaq * arc ««Hin E*pr*««BtatiT«
(iv^aBaLTftlc traatBVBtc act
tatvlataa. Th* f«»«lblllti of a
leliatlc, no-*»»k pollei fax hair
aaalTaia 1* cmtlln«4 aad supported.
tlTICT: TB1C! tiimwts; Bin;
ICSTBtHl; BIASQBVBBVT RRBQOS;
irtiis; fBornis: COBPUITITI
fiiimiOES; itvalKiB: IRIBOIT:
1SSCTIC; BUIUB; BIOBIIIj CUMOT;
ciicnrB; CBicsiii: ctmoaius: COBUT:
copvn: smma: OEintnvB: COLD;
»6B«sioi: aiasujss: BEBCOII:
BOtlBDIIHH; 1ICKS11 nOSPEOlOS;
CCTIS3IVBS VBB1BIV9I; SBLEVI1TB;
S1IICOB; SXLTEI; SODIDB; SIBOITHTJ:
SVlfm? Til; CTY1VXDB; TVBGSlEt;
1IBC; IltCOlIOa
a) Coitroll
tl 8alti.fl* iclccoalc patlcata
Saapl** fxoa 7 scalp aitaa la each
jvb 3*et

CIII01; IDOITS; CEITU1 IE B TODS
£T3«B DISUSES; "Att; 1LOBIIQB;
BIDB»E; cucinn; CRIOBIBE; COFFEE;
ccto: I09IBE: BHCUESI; EETILS:
imiins; sitTini sooioii; snrm:
tiiioivs: ziBC
EEPE1EBCB

Unlsaon, t.B.
Dasaaa«l*er. G.6.
Joktuaoa, T.B.
Uncb«ater. J.t.
W7*
lanala of Occapatioaal
BT9l«B« 19:225-23*



ChitU«bozo«gh. 6.
1980
Scl»nc« of th* Total
EnTitOBMut 1«:5J-75














Byu. D.E.
Eolxbeckcr, 3.
Stuart, D.c.
1971
Clinical chnlatCT
21(11| :199S-2000





                                                                                                                                                                                         to
                                                                                                                                                                                         03
                                                                                                                                                                                         Ul

-------
Tellarlaa
13494-sa-*
I«
Bt 127.6. IP 449.5 C. ft 989.8 C, »P 1 ma B» at 520 C
«ss«
4490
xidaey
»wi
Liver
4(92
Laag
nfosm BOOT



kuimcu
Banco
n
u

BBBBEB
OF C1SSS
•1 «
M 19
a) 8
b) 19
8
19
IMG*
a) < 0.005-0.33 ag/g
b) < 0.005-0.2* ttg/g
let *t
a) < 0.095-0.12 ag/g
b) < 0. 005-0. 12 «g/g
Vat «t
< 0.005-0.025 «»/g
< 0.005-1.06 qg/g
at vt
Bsii i CBIBIU. IBPOMMIOB i nramicx
i i
1 !
a) Rot givea I a) Coatrala 1 Brate, D.
b) lot givea | I) Workers, groaps I aad II I Borabarg. 6.
1 | lastor. ?.0.
I laceased reflaery aad laaltai I 1900
j ccrkara, *ge* 55- TC ft, expoaed to 1 Scleace of the Total
I taavy aetala 1-3 decades. Claa 1 Eoiironxint It: 13-35
I tatnaaa ratltaaaat mtt daatl 0-1.5 rr 1
I ii qroap I ul 2-19 TC, gceip II. 1
| Coatroll, aqta 43-72 yr, *to lital 50 (
| ka froi tka factory. Svadaa. 1
1 1
i sitwi: eatiTBSi KiDasrs; iirsi; t
I uiss; comiinn immiois: i
I iiDBSTiiii noiEHi actsomni i
t BIT BOBS j innoit; usnic; i
1 inimna: ciDfliiB: cssim; CBBOBIDB; i
| CCBalT; COfPIl; COLD; IMI; I
1 iiRBitui: LIU; uieiRSB: nictuT: i
I lomotnB: laospsoiiis: BDBIDIOH: i
| SC1IDIDR; SBUIIOf; SIITEI; TIB; I
I TVKSTK: ZIIC; BJ1ITB HEUSDS; 1
| mOSnXal PllITS; SIU1TEBS |
1 1
1 1
a) fat giva* | a> Coatrola | B£vna« D.
b) Bat gim I t| v«rkats, groups I aaft II ! lordbvrg, S.
I 1 Waster, P«O.
1 laeaasai raf laarj aad aaeltar 1 1980
] icckars, a; BIIGIIBSB; BEBCTSI; i
I BCIIBIIBO'l: fflOSPBOIBS: BtTBIBIBi: I
1 scMDins: snttiDB: snrzB; TIB; i
| IHBC5T»: IIBCj BBU.TB MZUtS; 1
| IBOISTIIll ?11»TS: SIBITBBS I
1 1
1 J
Bot given 1 a) Coatrols | Broae, 0.
lot girea 1 r) lortecs, gioaps I ud II 1 Bordbacg, G.
1 | Waater, P.O.
t taoaasad ref laary aad aaaltaz 1 1980
I tcikers. aacs 55-76 yr, axpaaad to t Selaaee of the Total
I Iraarr aatals 1-3 Oacadas. liaa 1 Hnricoaaeit 16:13-35
| tataaea iatlraa*»t «»4 death 0-1.5 yr 1
1 la group I aad 2-19 yr, groar II. 1
I Coatrols, ages (3-72 yr. aho lltai SO 1
j ka Croa the factory. Svedaa. 1
| SMOtB; CICaTXRSS EI9BRS; llTBi; I
| IOBSS; COIPIHTITB ETltHtTIOBS; I
I IBEDSnilt BieiEBS; BKtSBBEIEBT I
| BITBODS: aBTItOBT: »S*IICJ 1
I iiitraivB: ciD«m; CSSTOB; CHBOHIBB; i
I CCIILT: cotrn: coin: isoi: i
| tlKHJUnS; HIS; BaBCllBSI: BJSOJST; 1
I tOlTBOEBtm: tBOSPUOlOT; BDIIDITia: 1
t 3CMOID3: SCItBIOB; SItt'B-. til; t
I 1B1GSHB: tine: Hnm BIHSIS-. \
\ IIDITSTII.I HUTS; SBSLTIIS 1
1 1
                                                                                                                                                                                       to
                                                                                                                                                                                       00

-------
t«rt-Mtrl iinlflt* (8 ci|
nl*«lfld«, fci*f1.*-dlMtkrtet»rl|  C»
CI-8U-S2
II 178.3*
tissn

«W3
Brcatk











sifosvn Mm













lutmcu
BITBOD
OC-BS











fJBBEF
or cisss
5% PB7
sa*pla*l











tues

lot glm











n>i
-
0.509 »g/l
0*oa*tllC











eiBtBu, inoBBMi«B

Rcaiond at 25 C aad 7 SO •• Bg
21. M occurroc*
le««t »»1 ivpar o*«-Sl.
Cticaqo. 11. sijiSlr contzoUcl
•tpnlmtil condltlots.
flllTB; I1CCIO1S; I11IIOIS: 1D01TS;
CE10IIIITID miOCllMfS; WllTILE
ciGuic concnos: RIIITB IIZUBS:
niitKTci; imtoiissj imiEounss
ICmiTtOI IIPOSISB; D8B1I UMS
isnsnirci

KtataniDiki. B.K.
BCUCN, 6.1.
0*1*111, S.3.
1»7»
Joarul of taalTtical
Tnicologj 3:225-2M







 11
     10*. 37,  B>  303.5 C. B> l»57 C. T? 1 M Bq at «25 C. 10 •• Bg at  1000 C
1 tissut 	

MM
cerebrosp
Ival
flald









Saliva













nnsm tens

l»«*«Uo.











-














1BU.KXCU 	
IBWOS
las












US













IDBBM
Of C1SM
1












1













MB6B

lot givex












a) «-0. 2 ag/al
b) 10. 15-9. IB ag/Aar













	 isii 	

0.2 ag/1












.. - ,
a) lot glna
b) Bot glr«i













GCIlnl IITOISITIOI |

! dari after 1 a.

28 jt old, koapitallnd * dajs aft«c
lagwtlag tkalliaa Mltato.

lover abdoalaal pai»v aavcaa.
>TC«r*sthaala of lliba, roalting.
l«tbam, dte«*lMS*, dacraa««d blood
Tt»a«r«. len of scalp aad tody
kalr.
mttios; iiiiL Foiscwiis: CASE
11S1O1IBS: 01I«1; SttlTl; IT1LI:
ftCtS; SOICICt; CEtBBROSVIIU TiaiO
a) 7 aad 23 S«T» a(t«c t g
b) DCT< 7-» aid 23-2« attar 1 9
San valaes aatiaatad froa gzapb

26 JT 014, koapl tallied « day* after
iaq««tl*g tkalliaa calfate.

locer akdoiiial p«ia, aaiee*.
hi^ecaatlieaia of llab*. voiltlag.
letkargr, drevaiaaaa, dacreaaed blood
|t«*nre, Icia of acalp aad bodf
bair.
ICUUHB; Btlll fOISOIIIS: CUt
iisiotizs; nintj sutft: ITUT;
nets; smciiz; cnsBiosmu. naio
XERBHCB 1
1
(ickelal. r.
fioao, T.
iSaardla, I.
retrial, B.
Banto, 1.
1980
icealm at Tozleologr
(3:321-325





Blchelai, t.
Bono, r.
«aardla, I.
recrixl, B.
lano, 1.
1980
trcKlTes of Toxicologi
43:321-325







                                                                                                                                                                                        t-J
                                                                                                                                                                                        09

-------
  Italltae
  Itl 2»>.3T. II 301. S C. B?  1*57 C.  TP 1 »a So at 825 C. 10 aa Bo: .t  1000 C
XXSSVI
419ft
Vrla«












imsns torn
I»«**tlOa













immcn.
•rraoo
us













nun
or ctse
,













itiei
5.6S-0.2? »9^«y













mi
(at * | | i) tot giT«B
1
1
1
1
1
1
1
1
1


t
1
1
— — — . 	 *
1
t












uti i 6! ni»t uroiunai
1
•
a) S.3 Dj/al | a) I?0 aa/8 ir ta «t«dr »t«t»
bl «. 9 m/il I t) 350 •«/« kr plu 100 aq
1 aHopariB«/8 kr to steady atat*.
1
1 t«a-*aok«ri, aa«* 29-35 yr, on
1 iaatklM-fr<« dl*t »8 kr.
1
I I9SI11I.I1; ItalTS: BLOOD PllSfll;
1 otiitt oivs iirsticfio*: noes:
1 CCHMRITITt ITII01TIOIS:
I TBiopmiiits; tmnsi BRIBOIISI;
I imtotrres
i
1
a| 104.9 tor- *.$i! of | a) 250 aa/l kt
dos* | t) JSO ag/* fcr plu 100 ag
t) »*.B »or- 4.5* of I allopariaol/t kr
do** 1 TiMpkrUla* pl«a a«t*boltt«, ataadr
1 (tat*, ta 8-hr arlm. > SOU aa
1 1,3-dlMthylnrtc aeU. Data
1 anllabl« fct IT doa«.
t
1 lea-Mokara. aq« 29-35 ft, on
1 xaatkliw-fr*« aiat M kr.
1
1 itsniui; leniTs: HOOD PUSBI;
t OlttZ; 9(03 mitlCTIOI; DBOSS:
1 CCBtHlTlrr (TlLOIIimS;
I ittotmiinsi snins: imeociSRi
1 KiMotms
1 1
i nnmcx

i
t
1 STTfUl, J.J.
t 'la?. I.H.B.
1 Farka*. J.
1 Birtatl, D.J.
1 197*
1 clinical nacaicolojr
1 anJ Tkarapaatica
1 2«(5):««0-««7
1
1
1
1
1
I
1 CrrgUl, J.J.
t (lav. !.»-».
1 Fatkas, J.
1 Blrtatt, B.J.
1 197»
) clinical Fbamacolo^y
1 M« Tk*np«atics
1 2« (SJ : ««0-«<7
1
t
1
1
1
1
1
1
1
                                                                                                                                                                                            NJ
                                                                                                                                                                                            00
                                                                                                                                                                                            00

-------
            melt, ioi«aioaiir?ie*l oatlmts

ItULTS; BBM1 DISSISB; BtTOmSIOB;
noon-, aniBTntntsiTB IBIITS; noe
TKIUTt COBIUHITB ITfllOmOO:
smsran curai; TKOCIMITBS
a) SaokvrSr attar 0.032 if/kg fa
•actaria, IB iasa, 2 >k
t\ Sab*tact9 a>4 dosa aa ia a) v attar
1 ao abatcatiom froi sacking
Staa$T stata 1»»»1. »•«>«
• l^itifieaatl) AlCfaraat.

(aaltfeT 19-(0 ?r olfta, saoiei at
l«»«t t jack of elaanttai/oaT.
tlUSS; 3BOII16; TOB1CCOS; IICOD
tusus coBtumn wuonioss;
IVTlCQUllaVISs BWIB01I3B; TI1IBSS:
TBIOCtlBtllS
xsrtiact

Bognn, B.
ttOXOtf J.
Xarcki, J.
Giert, 3.
lagltli. t.
Bitkov8ka« B.
Colabak, I.
1979
Clinical Chaaistrr
25111:60-63
-- _
SaAaaBB, K.
Shapiro, S.
Taltoa, B.
Carroll, r.t.
SalliTan, T.J.
1979
Clinical Vaariacologr
aa4 TharaDaoticA
25 |3) S 309-31*




          p«BtaB* (lo
nssn i
•Ml
Breath












IttOSTOt BOOTI














1»IITTJCIL 1
vmvob
OC-HS













BQRBiS
or cisis
SO (3*7
naplu)












BUGS
Hot «lT«a













Ola I
0.421 og/1
OaT< 18-35 rr 014, nomaoklwi.
vctaa blacki aa< Caucasian.
Ctlcaqo, It. liqlill eoatcoll*!
«iB«ri«*atal condition*.
tBUTB; UCOtOLS: IUI10IS1 UttllS;
CHOBTI1TED BTDBOOIBOIS; 1OHTILI
cteuic coBtcoios: BBUTB BIUBCS:
iiauaTiOB; «rriBoiisa; BRIBOI.TTES:
fCPBtlTlOX lirOSOE!; OBB1B IEJIS
Bxnmcz
Etoto«T»»ii. B*K.
Bctncao. G.I.
O'Mlll. B.I.
1979
JOUMl 01 U»lTti=«l
TmicoloaT 3:225-234








K)
00
\O
           *,  1- (8 CI)
                                                             CI)
   91 776. 13, Vt 235-236 C (4«eo*p)
IISS11
• 502
eiooi.
tervat



ixrosnii BOOT!






inLnicu
IIITIOD






BtlBBIE
OF CISS5
2*3





BUGI
». 5-11.5 ag/100 al





BE1B
7.7 DJ/100 «1





GEiiiii iwrosainos


HCfPIOI'S: BIJSOBI1MT HETBOCS; BLOOD
smn*: Tttis

-
KIEtESC!
Broun, S.I.
•vtbeav^t J.
197*
Joortil of
Pharaacvatleal Sciaaces
«(B):11W-1217

-------
tig
7M9-J1-5


Itf m.C*. V 131.5 C, BP 2507 c. fP 1 •• Bg at 1C10 C. 10 u Bg ft M»0 C
I tissn i ixtosiu totn
i i
• i

































t 1
(503 I
lair


















a50l
Vale
1































lUtRICU
HCTBOO

































.
1

•ram
or CISBS

































MICE
















nil i esBEiu Mfoiawioi
I
i
i
1 tarln. M rapnsntatira
1 fre-aaalrsf a tr«ta«t« an
1 tabtUtvt. Ths fusibility of a
1 aelistie, ao-msl roller for hair
1 laalysi* la cotliaa* «n<5 «ipport«a.
1 tmn; met HUHTS; nil:
I lesnuti: mmmn serwesj
I (nits; itemise cotPiMTin
1 iTimnoiS: imiliW: iniwntTi
j nsnicj Bum; uonis; caraxm:
1 cucxoi: CBtaiiBt cRonoi: coeitr:
j ccffit: giuim: CTMHIBB: COLD:
1 icoiii: I»os; iiRiiini: l<»:
1 neiMUi: iiiGiissi: sncsin
1 loiTioEioB; nc«ni Mospnows;
I IOT13SHB; IHKlalVB: Sill HOB;
j I JI1TCOI; SIITBB: SOOIIBJ SIICIH0II

















1

i
• 1
I
\

1
•ws n


















































































a) 8 1 a) < 0.3-6. 87 s«/g
b) 14 1 b) < 0.3-S..W ««/»
| Bat «t








































1 3n tat; tit-, nruiii; TnEstn;
i me; nicoiing
i 	
1
| 1 ta>*i«v of >ocl4 lltaratar* OB taa>
1 a«c«atlatioa «»* blacoacuttatlon of
1 nlactsl toxic trac» aattli la amua
I kale aa4 aalls and otkcr aaaaaliaa
1 aair. far. atils, elans ail hoofs.
I Ktalatad bf geographic ana.
( *it5«eta-, ttt, a««, cxposara
1 gtiaivct, a»lrsas la pp*. aafl
1 ictaarltr fr«a or»r *00 za>far*Bo*>.
1
t irtrci; iDstiuii: CHIBJI! czniii
I iinici: mtctti iTDOtt list; in
t if HMD; SOUTH mild; somraasr
I mi t oviTte KiiGBoa; ontti stuts:
I fin; laits: imnt 4irin>ii:
1 »s»xc: BOBOI: ciBini: cnoiioi:
1 CCSU.T: ceatts tu*t racoti:
4 iicnt; snmvv: r»: u»oni; in
f (OtlOTIOl; IITUI *OPOHTIOIS:
| tTOICCOBOLKlOls BIOIBDICIIOIS! LtIO
I EOimioB: ropOLiTioi szposiru: run
I poitinios; TIICB Hire rrs: amis
1 lot gl**a 1 a) Covtrols
» fat eima 1 t> lockaca. grovpa Z tad II
1
1 r*c«ui4 rcflMty aad aaolter
1 •oikaca. agaa 55-Tf it, •xpoacS to
I l«»rf aet*l> 1-3 ivctdts. Ti»«
1 t«tw«a rvtitcaeat and dcata 0-1.5 r'
1 it groip 1 »d 2-19 yr. group II.
1 coatcals, agas »J-T2 re. »tt» Iln4 50
1 >i troa tba factory. 5*aia»w
t
| SMOCr; CJDJTIBS; ZIDIBTSt 1ITFI;
I HUBS; coRMiiTin zritDiTiofs:
{ III«STtIlt ITGIEHi msnXBNT
I iwaons: tvtiioti: Msmc:
I itu
                                                                                                                                                                                         o

-------
 tin
 TMO-31-S
Si
ati m.«9. n 331.9 e,  tt 2507 c,  TP  i ••
                                              »t  wio c,  10 •• 19 «t 18»» c
                                                                                    (COIIIiBID)
nasii


•06
HT.T





















aSOT
laag




















1
ixiosoti toon
















































IBUTTXCal
RETBOD

n






















BI






















BBRSSB
or cisss

) 8
t W





















•} 8
b( 19





















tuat


} < 0.3-3.18 ag/g
b) 0.3-3.70 eg/g
at «t




















a) 0.3- 2. 15 ag/g
t) 0.3-3.68 eg/g
fat *t




















B»B | GIIZSU XBPOIHUIOB
1
1
) lot givea 1 a) Coattol*
) lot girea 1 t) lockece, groups I and II
1
I Caeaaaed ret taerr and aaelter
| aacfcecs, aget 55-76 TC. expoaed to
1 keavy aetala 1-3 deeadee. Tlee
| batveea retireaoat aad doatk 0— 1.5 yc
I la gcoap I a«d 2-19 tr« group II.
| Ccatrola. agaa «3-72 yr. who U*ad SO
1 ka tzoe tka tactorr- s»«a«a.
1
t SUOII; CU1TCM; HDIITS; lim;
| IlieS; COBP1HTITB BT1101TICBS:
| IIDDST1I11 1JSIIIB: nUOIIBEIT
1 iiiBOBS: tniKiit usmc;
I TH.IH1IT1S; CIIIIOR! C5SCTB: CSIOBIDB;
1 CCBUT: conn: GOLD: HOB;
1 iimiBui: iiu: HKtBtss: incmi;
| BClTBOSIVBt IBOStmOtBS: «DU9T«>:
t SCIIDIH; simm: SIITIB; TIB;
1 ToissTSB: UK: asiin BIXUBS:
| IBPBSTBIll P11ITS ; SBSITBBS
1
a) Bot given | a) coatcols
bt Bot given I ti lortera, groups I aai II
1
1 Keaastd ref latry aad aaeltet
| acifcera, agaa 55-T6 rr, expoaad to
1 aaavr aatala 1-3 deeaiea. Tlae
1 tataeea reticaaeat aai deatk 0-1.S TT
1 la gcoap I aad 2-19 vc> gcoap II.
1 Controls, ages »3-12 ji. aao lived SO
1 *i froa the factory. Swedes.
1
1 iiiin: ciEtfns; HOTEIS: iir»;
I macs; comnmTS mimTioBS;
I 11DOSIIH1 BieilBC: BiaSOllIZBT
1 BITBOBS; miaOBTs USBBIC;
1 lllimni; CiDHTOB; CSSIOT: CEIOBIOH;
I cciui: co»a; COIB: HOB:
1 lllTBim; IUO; BlBGlBKSBt BElClTtT;
1 BoinpEBaa: IBOSWOIBS; BUBIDIOB;
l scininii SZUBIOR: SILTIB; ni;
1 IBBGSTBB; XIBCi BttlTB B1Z1IDS:
1 IMOSTBIll IUBT5: SUBIIMS
1
IStttSICI


Bcaae, D.
Bocdbecg, G.
Beater, 1.0.
1980
seieaee of tka Total
Eaviconaent 16:13-35

















Bcaaa> 0.
aoxAbeTg, G.
aestar, P.O.
1980
Scleaoe of tke Total
Enviconaeat 16:13-35

















                                                                                                                                                                                         VO

-------
Titallaa
1MO-32-C
II
It* »7.»0, It 1677 C. TV 3277 C, T» 1 U If at 2180 C.
                                                       10 •• Bj at 2*80 C
TISSUE EIKSVIE tons IMUTICXI
S PI BOB
»SOS
lott»
1
1 1
1 1
1 1
I
,,0,
Brain
1
1 1
1 1
1 «519
1 Br«th
(Sit
lair
i
Ittalaticn

n
n
i
i
I
put

xmm i ii*e* i BSII i eiiniL nromnoi I OTEIEITCS
or cisis ill 1
i i i i
t ll I
2 | < or • 2.8 «g/g (*«t *t) 1 t.< « or * 2.0 »«/g I »«!«« 1 T»ka»a, a.
1 1 (»«t »t) | » Saioltl-Taawoto, B,
1 1 | »ro« a 4»ap of «1 aatopslaa, 1 aaaao, K.
1 f | femtslc ladteal •xaainati.ODa. Japaa. I fatal. H.
I I | Balw naa *g» »0.6 jt. Paaalas, I 1*80
I | | ««aa ago 37.* TT. | Ireklra* of
III | t>Tlrona*ntal Hoajtk
| I | 111CZ ItSIZITS; aVTOPSIKS: JaPtl: I 35(1):3t-««
1 i i jioiiiDi: itstnc; CIDBIBB: COJU.T; i
t | | CtlOIIiri; COITIS; Ito>; BIICOII; |
1 i i ntxai; iinxstvi: uiamsx; i
| | 1 mniORs 1KIMR; SCllDISg; 1
1 i i SMWIOS; tnuiaii nuDtoi: me: i
l i i eciB; BBOsiH; IITXI; rrpiiis: i
I | | CIIJBSnlJ: CEMBKILVB; HUT; RVSraSS; I
I i f tucmss stittrt imss; ton*: i
I | | BCTU3: COBPM1TJTI CT1LOITI013: 321; 1
I | | TCttlSIC NDICIM |
1 1 • 1
1 1 II
1 a) »OB« d«t«ct«J | a} «oi« 4«t«ct«d I a) lain, cvnbraa, 9 iobl«ct» I Takava, 1.
1 b) < or « 9.5 ag/g («at I i>) •-> » or - C.7 I t) Taaalas. c«r«bria, 2 *obj«ets I 5anki-Tan*oto. B.
1 vt) | o?/g (>«t »t| | c) »«!•«, c 1.* os/» (nt | c) O.JS » or - a. 62 I t) remits, cer»b»lltia, S »ot1«ct« I Teral, B.
1 «t) | mg/g (»et nt) 1 1 WO
|t> < or • 3.6 aq/g (»«t ( J) 1.3 » or - 1.8 1 Fzoa a nconp of 61 «ntopsi«a, I a r china of
1 »t) | »j/q c««t «t) | foraaslc a*iieal axaainatioia, Japa«. 1 Inrlroaaeotil Bcaltli
1 f 1 Bales. MBD ao« ao.« ft. I«»alas, I 35(1):3«-««
i 1 1 i«an aq« 37.* TT. I
III 1
1 I | TMCt nniRS; aOIOISIIS; J»PH; |
I i i mania: itsnic: CJBSIOI: COBIIT; i
l i i cnoBioi; corm: cioi: BBBCUST.- i
1 1 1 I HITS; SKBISIOB; »«»S1IESI: |
1 i i igeioiDR; amsoir,- SCJIBIOI; i
1 1 I snnlDI; T1I1«IO»; MWPItJS: ZIITC; I
1 i i sen: Homi; LITZE: nottis: i
1 1 | CtSZBIO*; CtEZBEUDB; HBtRT; ROSCLXS; 1
I | (iVCBEIS: SPlEEIs 10KSS; 10ST1; 1
1 | anilS; C01P»I»TITI ETUVITIOITS; SBI; I
1 I fOEZISIC BECICIIE f
1 1 1
1

I
1 Wot glYtn
t

12.2 14 1 « 1 saapla4 at rat* of 1 1/aia, 2-10 1 lltMlaaoa, X.I.
I ala aftor tenlng • arc *«Ulaq rod a. I De»«4ela«r, 5.G.
1 1 Johansson, T.8.
1 Oai»erslt» pbraics stop, rlotlaa 1 Blcchoster, J.I.
1 1 1»76
1 KCBIDl; lEOtTS; 3RE1I8: CllCIHR; I inMls of Occupational
| CtlOtlfZ; CIWCIOI; COPPEB: I8OI; I BrgleM 19:225-23*
I IZIB; ntieiiESE; ncrst: POTISSWH; i
l Sturm; T«»nnn; TIUDIITH: me: JIB i
l foituTioi; nets; iiairsmu i
l iimsranzs; TBICS ELEBEETS i
< i
1 i
1 B«»ia». 2« Mpraeitatin I Ctittlaborougk, G.
1 Fr»-aBaljsls trcatmtc ar« | 1980
1 tabulated. Tba fMsiUlity of a I Science of tae Total
I kallstic. ao-«asa policr for kair j Zn*lra>Mat 14:53-75
I aaalTals la entllaod aad snppocted. 1
1 1
1 ff«TK; TMCt SIEKZtTS; Ha»: I
| JCSTBU.I1; 8USOIERER OTISODS: I
| CZTUS; fSOItnS; COMPUaTITZ |
| HllC»TIO»S; 1IDRXJVB; »IT1BOTT: 1
1 nsntic; EuivH: BBCRTIE; citBian: i
1 cueing cBiCBiii: CHSoaitui co ant: i
l ccrecs? sjiiros: sssniliiB: eon: i
1 ICDTIE: ttoi: nrrmiuB; LI»C; i
1 B»a»isns: BHG*IESE; SIBCOSI-. i
( tciTBDEni; ncKn: EBOSPBOSOS; i
i tcmsios; iminitjii; SSLHIOI; i
l stiicoi; sum: SODIUS-. snctrioa: i
1 SOITOB; TI«: Tninm: TVISSTM: i
I IIIC; tltcomH I
i i
tvm •««>


NJ
O
S3

-------
YitaBltS
TMO-J2-S
II
1W 47.99,
           HP 1677 C,
                         3277 C,  vp 1  M Bg at 21M C, 1O M Eg at  2MO C
                                                                                       (COimiTED)
TISSUE



Ml 2
Beart



















«S13
KUner

















a5H
liver

















posiitt tarns






























































itumcaL
RETROD























a



















Wat.

















BOBBSl
OF GUIS


4
2



















) 7
b) 2

















ml 11
•1 •<
h) »

















I1ICB



< or » 1.1 89/9 f"*
t)
•one ietected


















a| < or » 3.5 119/9 (vet
vt)
b) lone detected

















•t)
b) lone detected
















iin i 6>UML XEromTiokT
I
i
I
0.28 * or - 8.55 I •) Bales
9/4 |ve>t *t) 1 t) Peaales
»on« a«tect«a i
I ftoi a »ro«r of <1 antopsi««.
1 forensic •edictl «E»iiatieH, Japan.
1 Baits, wan « a«a «0.« re. r«««les.
1 f«aa aq« 37.* jr.
\
I fllCZ IL1HMTS; 1OTOPSIES; JU»;
| H.
-------
Iita*l»
7»W-3V«
11
Itl «7.tO. HP 1S77 C. n 3277 C,  TP 1 aa Bg at 21*0 C,  10  n (9 at 2«to C
TXSSBI
1*14
t
1... 	 	
Etposau toon
1
IIUTTICU
Btnoo
n
I t
(SIS la
Buelo
1
1
(
f
1
1
t
1
1
1 1
t 1
f 1
' . «
* 1
i «st7 i I n
1 Paacroa* I I
1 1 1
« 1 1
t 1 1
1 1 1
1 1 1
1
BKMEt
Of CISZS
a) 2
•» 2
1
1
a) S
b) 2
Mitt
a) < or - 2.7 »?/9 (Mt
Dt 0. 60* 1 S ag/4 (vot vt)
a) *oa« J»t«ct»4
i) < or • O.CS 14/7 (*«t
i
Biti i CEIIUL xiroiimo* i XERUICE
1 l
l <
a) 1. a * or - 1.» 1 a) Balaa | fakan, B.
tg/y (nt »t) I t) rmalas 1 Suaki-TaavBOta, B.
M 7.8 + or - 10 tg/g | I IBMO, I.
(»«t it} | Feat a groap of 61 actopsiaB. ( T»rai, B.
1 foraaslc Badieal «aalaatlou, Japan. I 1*80
| lal«B, a*aa ago *O.C Tt. rcaalae, f Irehlnc of
1 a«aa aoa> 37. a rr. I EBTlroB*a*tal Boaltk
1 1 35(1):36-««
1 ntCE ELtBtns; tBTopsras: Jirti; i
| linXI9B; IfSElIC; CUHIB; COBU.T; 1
l cnoBioB; ccmi: XKIB; sttcmr: i
| I1NTIB; BKBESIOB: BIK1IESB; |
| iHBIBIBS! IHXBOlts SCMBIOfl; |
l smiXBB; trnixm: TIIIBIOB; UK; i
| SCLB; SBOBIBt: UTR; KBIEIS; |
| CtlUBIB; CtiraELLOB; BXHT; BffSCLES; I
| PtKIMS: SPIEXB; 1OTSS; lOKTt; I
I BETUS; CO§PU«TITB BTaigitXCtS; 5BI; 1
I FOEBSIC BZeiCXIB 1
< 1
1 1
al roao aotoctod I a) Balo* | Takaaa, B.
») 0.08 + or - 0.23 | t) roBala* | Saxakl-Tacaaoto, B.
1 Iroa a groat of ft aatopslaa, ( Taral, B.
t faraaile BOdleal axaBlaatioaa. Japaa. 1 1980
1 BalaB, BOBB ago «0.« rr. rcaala*. I Ircklna of
1 aaaa ago 37.a rr. | EBrlrauoatal Malta
1 | 35(1}:36-M
1 TIICE ELSHEBTS: iOTOMISS; jaral; I
I »inBiim: IBIEIXCI CIBBIOB; COBUT; I
1 cnoBiira: corrEt: xioi; SEBCOBT: i
I MBim; BietESIOB: B»ISl»B5t; |
l loeiorjg; atrxBoiT; SCHBHIB; i
t tiannt ixmxm: THIDIOB; IXK; i
I eOlD; raOBXIE; UTEB; CIDBKIS; I
I ciisiKn: criESEtins; asm; HOSCLES; i
I MKXHS: SP1EEI; LHBBS; 10IT1; I
t BRalSi CORPIItTXfE iritOHIOUS; SEX; |
I rcmsrc BIBZCXII i
1
1 a| < oc - 7.5 ag/g (>ot a) 1.3 + or - 2.2 a) «at« I TBka«a. B.
»*> «J/g (»ot »t) t| r«a«l«« | sazakl-tasuoto, B.
b) < oc * 3.7 ag/g <««t •) 1.9 » or - 2.6 | liana, t.
•t| eg/g <««t »t> Itoa a groap of «1 aatopslos, 1 T«ral, B.
for«a aea 37.4 rr. | E«TiroBB
-------
TltaalM
7UO-32-6
Tl
It* 47.90. IF 1677 C. TP 3277 C, TP  1  M  Eg «t 21(0 C, 10 •• Sg at 24»0 C
                                                                                       fCOKIISEI))
TISSUE
4S1t
SBlM*

















iinsnx BOBTE



















1UITTICIL
SET HOD
SI


















mm
OF C1SIS
»» 5
b) 3

















11WSB
.
») < OX - 4.2 «J/9 («et
"t)
b) < or • 6.* «g/g t**t
•t)















Bill
a) 1.8 » or - 1.8
»9/9 !••* »*>
b) 2.1 * or - 3.7
•9/9 (••* »t)















EHttU IBTOIB1TIOI
a) Bales
t) f«Ml«

riot a.qcoip of 61 nrtop«i€«.
forflasic atdical ezaHlaatioo*t Japan.
Ral«. •••• af* 40. C TT. F««alea,
•tan a9« 37.4 Tr.

ttaCl niailH; aROKIKS; J»i«:
itmnns: iiswic: cuncs; COBILT;
CtBCSTOH: CCR11? IBO1; BIBCTOT:
HEitn; BESIISIOB: meansi:
iimivt; iRUoiT; SCMOIOI:
siiiiiBS: tiTMiim: muiaB; sue;
SCH; MOIIII: LXTSB; KIBIETS;
CEtlBSSH: CIBffltlLOl: RS1BT; HOSCtSS:
I11CBUS; SIIEEI; LMG3; IORTI-,
srriLS: coaeuaTXTi srixoitiois: sn;
TCttlSIC HIEICIII
BI7EEMCJ
Tnkava, B.
Suzakl-IasoBOto, a.
llano, I.
letai, B.
1980
trckiraa of
EOTiroaaeatal Health
35
-------
     lolvene  (8 CI)
     Benzene, (ethyl-  (9 CI)
     108-89-3
     C7-BS
     HI 92.13, HP -95 to -94.5 C. BP 110.6 C.  IP  36.7 u  Hj at  JO  C
                                                                                           (COBTIfVSD)
TISSUE
4521
Breath












EXFOSHIE BOBTB














IIU.TTICU
BSTSOB
SC-BS













HOHBI5
OF USES
54 (387
samples)












Bluer
lot given













•Ell
9.0 ng/1
Geometric












G1IEB1L IirOSBlTIOI
teasared at 25 C and 760 mm Sq
100* occurrence
tome and op pec one-Sign Units 4.0
and 17.7 ng/1

aealthr. 18-35 yr old, aoasiokiag.
orlan blacks and caacaslaai.
Chica^Ov IX. Higidlf controlled
€lp«rlaental conditions.
B811TB; 1XCCBQLS; HttBOIS; 1D51TS:
CBIOEIIJTM imtOUBBOSSi »OUTHE
CBGllIC COBPCO«BS: HB1LTH 1121805;
iiBiUTioi; arriBOLiSB: BZTAEOLITES:
Ecpnmrow imsvtE: VBBH mis
IEFIE5HCE
Krotoazynslcif B.K.
Brnnean. G.B.
C' 10 ill. S.J.
1979
Joarnal of analytical
Taxicoloar 3:225-23«








Iala«na-2,5-clla«ii«  (I CI)
1,«-BrazeiwalaiiM,  2-aethyl-
•f-TO-S
C7-B19-12
il 122.17. ITF S* C, B? 27* C
                                    CI)
tissiri
4522
urin»








IIPOSUSI Botns






1
1
1
1
I miTTICll
BETBOD










I BUB3SS
f OF C1S2S
1










I B1ICE
I
1










BE1«










GUIB1L IIFOBBlTIOf
(•Tie*. local and sr atomic effects
relating to hair dye floravlation.
iaqcedient tests* and experiences in
•ae and aflisals.

tints: Dis!»TTTis: IIOPIISBS: asiKE;
II TITBO 11ILTSIS: IB TITO 1B11TSIS;
BFTIB"! DIES; CIBCIIOGSIT; COSHSTICS;
GIBETIC fFFICTS; BE1LTS HlItBDS;
BITJ90IISB; jrrilOLITSS
BEnSEVCE
Karzalli, F.I.
Sreeo, s.
Haibach. 8.1.
1978
Journal of
CaTirOBMBtil Pathology
•ad Toxicology
1! 50 9- 530


Tolaener  o-nitro- (8 CI)
C«Biena,  1-iethrl-2-Bitro- (9 CI)
St-72-2
C7-«7-»-02
BI 137.1, BP -4.1 C, BP 222.3 C, TP  1  •• Hg at 50 C
IISSV*
»5J3
Breath












ElfOSVBE BODII














jtmniciL
BETBOD
SC-BS













BOSSES
or C*SES
s* oa?
siaples)












BalSE
lot glren













BE1B
3.040 s.g/i
Seoietric












Gr»iB»l IIFORBATIOI
Ceasnred at 25 C a*d 760 •• Bg
1». If accarreitce
Io»r and up pec one-Sigia lliits
0.017 and 0. 139 *g/l

B«althT. 18-35 TC old, non«»okt*i.
nt tan blacks aad caacisians.
Cbicatjo, 11. BioldlT controlled
eiptriaaatal coiditioas.
l*E»TB; IICOEOI.S; Illliois; units:
CttOBKMID HTDBOCIBBOBS; TOLITTLS
CBG1BTC COECOntDS: EE1LTI BllattCS;
1IBH.HXCB: BETtBOLISB: BE11IOLITIS;
ECPUL»TIO» EKMSmE: BSBliB IKEIS
IEF£1E>CE
Ecotoszynski, B.I.
Bcaa«an, 0.5.
e'nelll, e.J.
197"
Journal of Inalytlcil
Toilcology 3:225-2M









-------
Total BBC  (la porttaes  in
CS-BS-O.8
n 290.85
nssn

»52%
Blood













•525
PlaeeBta












'IPOSOBB BOUTB






























IBUTTTCal
BBT8OD
sc-BC














CC-BC












1
mass
OF CISBS
a) 25
M IS
e| 10












a| 25
b) IS
e| 10











la*GB

a) 18-85 ppb
1) 62-16S pp»
e) 105-550 ppB












a) 12-53 ppb
b) a 1-1 05 ppb
c| 31-134 ppb











BSaB

a) 52.5 * or - IS. 2
ppb
bl $3.9 « or - 22.6
ppb
c] 20». 2 » or - 141.2
p^ib









a) 2T.2 » or - 11.«
PP*
b) 62.3 * or - 13.4
ppb
c) 90.7 » or - 31.7
ppb








fiBKBlL IBFOBimoB

a) Coattols, fnll-t«ra pr«?n«ncie»
t) Pt«-teca pEegaaades
c) SpoataaeovB ibortima at laaa than
fl vie

EaaltliT* aoa-^xposedf prvqnaat voa9ii.
ages 18-32 yr, tadia.

IBCIt; IBOETIOI; U1ITSS HIOS;
HOOD; piicim: coniiswni
HUUTtOIS: CHLOBII1TED
«T9tQCMBO«S; CEIOBIII O561IIC
CCBP00B9S: KSECTICIDBS; PISrtCIBIS;
ttsticioi Eisioais; POIOI.KICI
IIJOS0BB; PIIGBIKT
a) Controls, fall-tera pregnaacles
t) Pra-tera ETeijiattCies
ci Spoata&coaa abortions at less tSian
3 >k (inclndaa fetas)

Bealthr* Boa-exiwaad. pregnant itoaan.
agaa 19-32 ji, India.

IlCIl; IBOETIOI; UILT3; FIUS;
ttltuillOKS; CBlomilTXD
BIDMCUBOIS: CH1OEIIS OB611IC
CC9KOIOS; lISICIICIIESi P1STICIDIS;
PISTICIDI BtSIDOES: POPDLllIOS
ItHSDlB; PBIGV1BCT
BEIBBEBCB

Saxena, B.C.
Siddiqil. H-K.J.
Setb, T.D.
Krishna Harti. C.B.
Bhargara, I.E.
KattT. D.
1381
Joaraal of lualftical
Toxicolo^T 5:C— 9






Sa-xena, B.C.
Si-ddiqti, 9.K.J.
Seth, I.D.
Krishna Bortl. C.B.
Bbanjara. l.K.
KottT. ».
1991
Journal of Inalrtical
Toxicology 5:«-9





                                                                                                                                                                                             K)
                                                                                                                                                                                             VD
  Ictil rot  (lo paaUiiqs In CRHIIICI.
  '9-M-3
  C1»-B»-C15
  B< 35*.50
iisstn
»5»
Utpow



















IIPOSOM BOOT!





















IHinlClt
nrraon





















ITWBTB
OF CISIS





















BtVGt





















BMl





















«I1IB*1 IIFOBH1TJOI
B«»ie«

Iipooed persons la the United States,
tfe« «»tli«rlajiis, SxnJati, Israel,
Japan. OSSB, Polanl, Servaaj, laiia.
Ellqacla. P*klstam, listrio.
Eipott*! «a««» at liTpettemlsa,
e lava ted satoa cholesterol^ abaoraal
•tea, oc iafaltaaat of Bcncoanscnlat
fvtctLoa aftac acnte «xpoa«ce to
eoabinatloat of pe»ticilea, tat mast
data ski" DO alters* «ffecta after
loaorteEH occnpatioaal ezposate.
insruri: ITUGUX*; ctsBini; IIDU;
ISHBl! IIP*!: IETBSELIWDS; PISISTII;
ICL1ID; BDSSIl; Stntf; nllTID
Sims: IBIPOSE nssni: BLOOD: BIOOD
ffllSfia; 5ICCD SlSHi: KtTIBSOCTTES:
nvKocms; eiu; VBIBB-. sinis;
flll-H B1Z1BCS; OCCOP»TIO«I1 B1UBDS;
fcfiimo* iieosoi:
IBTEEZBCE
Oeichaann, V.B.
HacDoaald, I.E.
1977
Vcotoxicologr aod
Enflroaaeistal Safetr
ljM-110















                                                                                         («!IT PUS El

-------
lets.1 >DT (*e postieqs U cmttnt.
50-29-3
CU-B9-C1S
II 3S4.SO
                                                                                      (COfTtWOZOl
1
1
1
t
r
r
i
i
i
i
IHJB1
•527
imlotic
flald
•528
Blood
1
1
1
raposun IOOTE

t
isaimcu
Bx-YHGO
OC-EC

i
>SM I
I Blool, |
I plassa 1
1 1 1
1 1 1
t 1 1
1 1 1
1 1
1 1
1
1
or cuss
50

20
suet
O.S-26. * ppt

•| lot oirsn
b) lot gives
Bill | GBIItll IfrOtimOI | HntmCC
1 1
1 •
1 1
23.83 ppb | *3 positive ipeciseas I saxea*, B.C.
Seoaetric I 1 Sett, I.D.
1 reeosaat meo» sisilax ia f Bahalaa. P.I.
| ««cioeea*o*ic level a»fl dietary t 1*80
1 bablts. Xo occnpatlosal or 1 lateraational Joarnal
I acclaestal eipossre. lockvov, India 1 of Eoviroisestal
I I analTtical Caesisttr
| F1SHCIDBS; CBLOIKUS9 HT9IOC1XBOTS; 1 7:Z«5-25»
I CEIOJIBJ CICIRC coapooiis: cop; 001; i
I en; unit: HBGHICT; «B«IOIIC i
1 iioiB; mcmt i
i \
1 fevlm I Delckaaim, «.«.
1 1 BtcDosaU. *.t.
I Opond persess la tke Halted States. 1 19TT
I tke •etaexlaids, S«e4e>. Israel. 1 teotoxieolotr and
I Japan, VSSI, rolaad, Oereaaj, lodla, t EnviroaMatal Safetf
1 Bulgaria, Paxlstaa. laitria. 1 1:89-110
| 8«Fort«i eases at trperteaslas, 1
j elevated seru ekolesterol. abnoraal I
j M6s, or ispairaieat of Besrenflcel&r 1
j fMctles after acate eipoaara to 1
1 cosbiaatloBs of pesticides, bat sost 1
j dats skos no adverse effects after 1
I long-ten occapatioaal expossre. I
I 1
I KST»U: BDteiiii; eniiii: acin i
1 isian.: J»P»I: nitnims; tuzsttts 1
I idiHi; snssn: SKDSi; mm i
I STH»S: IDIPOSZ Ttssm-, twos; ILOOD i
i ztorocftes; ait: viat; iifisi; ' i
| EMITS B1X11IS; CCCIPJlIIOIU. R1IMDS; 1
1 tcpratno* Mposait; SSOPLISBS; i
1 flSTICIOIS; CHLOEIBI OIGIIIC 1
I CCBPOBIOS |
1 1
1 1
a) 38.18 ppb 1 a) Ixposed I Bich*rd*oB, J.I,
b) 6.69 ppb 1 t) coatrols 1 tell, J.I.
1 1 SaBdlfer, S.B.
I 8*g Croa Soatlt Carolina Pesticide 1 19T4
1 St>o> exposed to slxtare of CDT, I F»rltoae»rtal 7e search
1 patatkloa ail carbaryl. Controla. 1 9:290-29*
1 with so knevs pesticide exposure, I
1 tatc««l «itk exposvl aroip fox aie, |
1 race, sex at. 1
1 <
1 slqaif least correUtioas of tot 1
I elevatioa asd ckoliaestersse 1
j depreaslon vitt elerated svatollc and 1
1 dlastollc blood rcessares. j
I 1
I SCOT* cMoriii: IMOB PUSBI; DOT; i
1 flSTICIBSS; BZI1BOUSR; OCCDPaTIOItt I
| llfMDS 1
1 1
                                                                                                                                                                                         VO
                                                                                                                                                                                         CO

-------
total BDT do pacttio* la CI1BLIH}.
50-2*-J
CH-W-CIS
(1 35*.59
   TISSVt
   530
   laofl.
   •S31
   Hacctta
             mason torn
  lxa»-t-toMMl  tie
                RMsm ion
                                  RCTffOD
                               ac-cc
                                                   IDS BIS
                                                  OF CASKS
                 ppb
                                     200.91 ppb
                                     Go ow trie
                                                                                                                        esitui
                                                                                                               lipowd pcncas la tk» ttitcd States,
                                                                                                                      US*.
                                                                                                               Filq«rl«, Patlitn,  lastci*.

                                                                                                               l« portal cas» mis

-------
1-TTTPtOpaaB,
<350-«9-8
C11-B 12-12-03
•« 220.22
            S-fcrdrorr-. I- (8 cq
                         (9 CI>
TISSUE
• 513
nood.
plasa*















EIKSnBE 10OTI
IlJeetlOB
inaestloB
















1I1LTTIC1L
BBTWJB
•PLC
Flaoroaetry
















BOBBxa
or ctsss
5

















BU6E
a) 2.3-0.29 aioles/T
b) lot gir«n
cj lot glvea
d) lot gl*ea
«) BOt gives













nil
al 0.97* » or - 0.068
naolea/1
b) 3.25 naoles/1
c) S.SO taoles/1
d) 7.81 uoles/1
e| 11.00 moles/1












GJMBIL mroiuiioi
• 1 lBlti»l •«aaac««««t and 9 hr after
24 (in IT of 0.908 iwiles/lcq.
tiexpowntial decline. leai is 9 hr
tiM-average
11 50 aq doss
c) 190 «a dole
4) ISO •? dcae
<) 200 mq doee
b)-a) 8 ir tiae-arelsge a«ias
c»pited fro gcapkie
at«»-»n4«r-t!»-ciirT« data aftec oral
dose/* ar
H-S2 TC aide, *t 52-»6 k«, nitk
ifocloiie disorders.
**asea. rorltlag
CBves; BBUS TBEIHT; mvo ICIDS;
iioao Ptisai: lEtraososctniR iisnsis;
leans; DIIRUK
1EFEBEIO!
lagaissea, I.
Ilelsea-Kadsk. F.
19BO
Acta Paaraaoologica et
Toxlcolojica «6: 257- 262













Tvnvsten
7»»0-33-T
*
It* 183. 85. HP 3«IO C. BP 5900 C. TP 1 •• 19 at 3980 C, 10 •• Hg at *«90 C
1 IISSOI | EtrOSDRS BOOT! | IHtTTIClL | KOBBIB | EitGE | BB»« | 6EIZBIL HFO8BJIIIOI
1 I 1 HETBOD | OF CIS IS | j
1 1 - 1 11 1
1 t f 1 g
1 *53' II II B€Tlew. 2« npreseatattve
1 "air || II cie-aaalrsls treataeats arc
II 1 II tabulated. The feaxibiUtT of a
II 1 II holistic, ao-vash policy for hair
til t aaaljrls ts oatliael aad supported.
Ill II
III 1 t tiriSV; TP1CI ELZirEBTS: HUB;
III il Ktsmtii: Hzis«E9en HBIHODS;
lit || FITILS; P SOT IMS: COHPlBlTlft
111 II IflI01TIO«S; ItaniOB: IBTtHOlT;
III 1 ISSEIIC; BIRIDI; BBOirJS; CIBSITC:
1 1 1 1 I ClICIOI; CIIOBIIE: CHSOHIOS; COB1LT;
I 1 I 1 terra: SHIIBH; sBsmnirs; COLD;
1 1 ICBIII: IEO»: L1ITI1BDI; IE10;
1 1 BIOIISIITB: BiRGiiEsi: iiscosr:
1 (ClIBOSIBB: HCKrt,; IHOSPSOSDS:
1 ECTaSSItlR: BDBIDIJ9: SBXEIIOB:
I silicon sinra; SODIOR; SIECITIOJ;
1 sin FOB: TI>; TITIUVI; TDIGSIIB;
1 ziic; TiBCOBinn
f i
{BEIT PIGS]

BMI IBS C!
Caittlebocoagfc, G.
1980
1 Science of tie Total
1 EETlcoaaent ia; 53-75

U>
o
o



-------
Illgstm
7440-33-7
*
lt¥ T83.IS, IP 3*10 C, BP 5»00 C, TP  f »  Bg at 3*80 C, 10 II Sg It 4490 C
                                                                                       (CORIIIBD)
ixssm
453*
KlSaeT
4S3«>
li»»r
4M7
MWI
fosvn toon



iHlTTlCAl
sntoa

n
»
DBBD
CaSSS
e
i«
S
19
*) «
b) 1»
1
1
MISS
< 0.003-0.005 v?/9
< 0.003-0-018 *«/«
t «t
1 < 0.003-O.OM oq/q
I < 0.003-0.01* 09/q
•t wt
•) < 0.043-0.011 09/4
b) < 0.003-0. 15 ng/q
let lit
	 iHi 	 i sBijiai iiroMaHoi t ssnstics
! !
i i
*>t gl»B 1 •) Co»trol« 1 Br«i«. D.
lot SiTO 1 V> lotlnts. groups I aad II 1 lorlb«ra> s.
1 | vester, P.O.
1 t«c«s«l refiBcrr »»« aaeltar 1 1980
I «rt«rs. a»«« 55-7S jr. siposed to 1 Science of the Total
1 lurr Mt*ls 1-3 a«c«d«a. 11» 1 ICTiconwat 16:13-35
| ltt««» catlm«*t **i Amtk 0-1.S yc I
| 1» qconp 1 nd 2-19 yc. ?rfl«F II. I
| Controls, a?«s 43-72 Tt, (to liwd SO 1
1 k* troi th« f«etorr. 3>«d«i. 1
t sum: cimtiBS; Kioirrs: IITIB; i
1 HISS; cospiiiTin snigmois; I
i iimSTSiit ixeiiRt nasnumi i
I inwus; niiBOii: usnic; I
t mumivB; c»BBJ0»: css:q»; csBo«0B: i
1 CCIU.TI cotni: GOU>; noi: i
i iiiTnm: tuoj lurainss: nicnsi; t
1 KinDBflfl: fBOSPBOIVS; IVIXDIOB; I
1 sciiBius: SIIMIBS: SIIVEB; ni: I
I ivissni: line: HUITH BKIBDS: i
I J1BB3TSIU JUITS; SBHTM3 1
1 !_._. _
1 1
\ lot 9iY« | *t co«*toli 1 Braea, B.
) lot 9ii«» 1 t) laxkers. groups I »»4 11 1 Borlbcrf. 8.
1 1 l«st«r« P.O.
1 t«c«»»4 r«f i»err ••» «Mlt«r 1 1980
I ictlmrs, ««•« »-7« rr, expowi to 1 Seine* of tie Total
1 kMiT Mtalt 1-3 awnfla. Ii»« 1 rn»iron«e«t 16:13-35
| t«twn tetim«t w4 4«»tli 0-1.5 jr I
1 i* qroip I »4 3-19 IT. group II. I
| Cotrola, «9« 13-72 rr> »'"> liwi SO 1
I k* fxoi tk» tietorr. SvelM. 1
1 t
1 SIZDMt C»»>«SS; Utinsj 1IT5BJ |
I itics; omrumn miaiTiois: i
I mvstiiai iiaitis; asaSDiiinr i
I CKBC9S: \irimn; usnic; i
I ttwniaa: caDangi CISIUB: CRtonvi); i
I cceiLt: comii SOLD; noi; i
1 laming: »u>; si»s»«si: HMCOSI: i
I tctnosmn! uoswoiust BOBIDIOH; i
1 5cmim; SHMUJS: sn«i: TI»: i
1 t«iesn«: IIK: HUIIH BIZUIS; i
| IlDOSltlal Pims; SBBITB*! 1
> 1
a) lot 9lT«n I *) Control* 1 Bran*, t.
t) lot alven 1 t) lotkets, o lima 50 I
t ka froa tk« tactorr- Sveiea. I
1 1
| SKDEI; C»»IES: (ItltTS; 1ITSS; |
t taies : coataUTin r»n.uiiio»s: t
I IlCDSTBIaL BTSIBIB; aEaSOHIinl 1
1 BtTBoos: UTUQH: »snic: i
1 Ttmrans; citRios; cssrnB: CBBOBUJH; \
1 cciui; COPPIB; SOLD: isoi; I
I tllTBlim; ItaD; 141MIES2; BMCTIT; |
1 sciTBOMOB: iBOSptoms: BOtlBias: 1
I SCalDimj SI1NID1; SILTE1: nit; I
1 tnisaiEi-, me-. BUMH aiiisis; i
I iBovsniti IURS: SIBHZIS i
i i

-------
  mulu
  7MO-61-1
  I
  Itl  238.029. IF  1132 C. B* 3818 C. TP 100 n 8g tt 3270 C
IISSJS
• 538
Satr

HMSBBE iOBTB


• B1LTTICU
HSTBOft
n

man
or cisss
5

I1I6E
0.25-10.4 ag/g

mi
lot gin*

esiiBii iBFOBBinoB
Eilk hair sasTlB*
lector* exposed iateraltteitlr to
aiaalea at the laxtraliaa atonic
E»rgr Co»»isslon *e*eacck
establishment.
iBsraiixi; Bin; ramos; BiisnnBnr
MXBOBS; OCCBP1TXOIU BaillOS;
iiBXOfoctnis: iBw>5T»i»i aioiii!
BEFEUBCX
san tier, <•'•
vr*tt, J.B.
1»60
iBTiroaseatal Besearch
J1:»07-«15

VaaaUas
7»»0-62-2
T
Itl S0.9«1«, Bt f»17 C,
                          3000 C. TP 1 •• Bg at 2290 C, 10 u Bg at 2570 C
1 IISS1S 1 BXfOStm BOOIB IMLTTICIL IBIiffl 11T6E
1 I BRHOD OF CtSSS
1 1

1 

TI1CE tLHIBIS: 1OTOPSIKS; J1P1B:
IIDBIBVI: ItSIBICi ClSniTB: COB11T:
CBROBMB: COPPEB; iao«: BIBCOIT:
IIBID9: IllSIISIOB: B1B61BISB;
IDEUIQI; 1BTIHOBT: SC1BDIOR;
SfLEHIBa: IITMI09; T1MDHJ9: flK:
SC1C; BIOBIBZi IITSB; KIBIBTS;
CIIIBiaii ClHBHLOBi HEIST; SDSCLIS;
F1BCXI1S; SFIIBB; 1VBSS; 10II1;
BII11S: COBFIUTITE ZTlt01TIOB5i SEX;
FOIIISIC BEDKIBE


Siblects froi 17 collection cites IB
the o.s.

SIIBBIBB; BCirBOSTOB; TlBlDIOB;
EIOOB; SSI) SOUTH DlKOTtj III TOBK;
ITCBTBC; BOBT1B1; OBIO; BISSI5SIPPI;
| | THIS; BOBTB D1KOT1; 11SHUGTO1;





a) Bot given
b) 0.0*-9.33 og/g (»«t
•t)
c) 0.03-0.23 ug/g (net
«t)
it 0.10-0.31 ag/g (vet
•t)















| CIllrOBJH; IB IIOH: ISDIIII;
| ICOIStlBl; 1BE1BS1S: TIOBID1:
t
1

riBBOBT; TMCB CIBIUTS


a) 0.11 * or - 0.09 | a) Bales, eoEebcM. 9 sableets
ag/g (vet «t( I 1) Faaales, cmkmm. 2 sabjecta
b) 0.18 • or - 0.21 | c| Bates, c*rebella>, 7 subjects
"9/9 Cet *t) | d) Feaales, oerebellas, S sol-)ecta
c) 0.10 * or - 0.06 1

og/g (cat *t) 1 Itoa a group of 61 aatopaies.
4) 0.20 » or - 0.10 1 forensic M4ic*l ezasiaatiois, Japan.
•g/g (net vt) I I
1 a
1
ales, aeaa age ao.S yr. Pesales,
eaa age 37.4 rr.

1 tElCE niBtlTS; IIROPSISS; J1P1B;
t IIBBIBTIB: JSSEIIC: ClDalOB; COB11T:
1 CBBGBIOB; COPPBB; ISO*: IIBCDXI:
1 iBcint; B16BISIQI: BIBSHISI;
1 latlDIQB; iniROBT: SCimiB;
t «IIJ»IOI1: TITMIOB; T1I1DIUS: II1C:
1 SOLD; B30BJ1I; 11TSI; KIOBtTS:
I cisiBsns; CSITBILLUI: BBIBI; EDSCLIS;
1 menus; spiral; LUSGS; icm;
l i
niLS: CO«S»I»TITI ITU.BHIOHS; SBI;
1 T01IBS1C BIBICIK
1

*EFE1EBCI



Tndan, B.
sazikl-Tasaaoto. B.
Icaio, I.
feral, B.
1984
Irciiies of
BBTiroaaentll Bealta
35(1):36-*»












lllanaT. I.E.
Kobota, J.
losee, t.
Eotb, n.
1968
ircalres of
EnvlronsaBtal Health
16:3>2-3«B




nkavav B.
nznki-TaSQioto, I.
saoo, X.
erai. B.
980
rchires of
EsTirotuatal Bealth
5(1):J«-»4














(«« tkSS)
                                                                                                                                                                                        o
                                                                                                                                                                                        ro

-------
faaafllaa
7«0-«2-2
             BP 1*17 C, tl 3000 C, TP I an Bg at 22*0 C,  10 is Bg at  2570 C
                                                                                      (COITIIKD)
nssra
«»j
Breath
MM
Bair
»SM
H»lr
W5
n*ic

MSVIB tOOYf
tUtLom




tlURICM.
BRBOD
I

n


BBBBS i MKS i mi j ouiiu nroiimoB i IIRIZICI
CiSKS 111 *
1 f 1 - - 1
114 1
1 lot gl»e« 1 0.7 if 1*1 siielrt at rat* of 1 1/sla. 2-10 1 IfcselMOS. K.E.
i || ala after bsrsing * arc nltlng roil*. 1 Desaedeleer, 6.6.
1 i i tun detection linlt. | Johansson. T.B.
Ill | Binchester, 3.1.
i | | BnlrersitT rhysies shop, Mariia 1 197«
III 1 annals of Occupational
i | | noiIBl; IBBIW: mini; dicing; 1 Hygiene 19:225-2J«
I | i caioBjBJ: ctaoaioas conns iiois i
I i i mot BI let 1KB; nun.: Krtissiw; t
I i i SBirm: iniHOH; TtuDioa: me; »i« i
i i i tcumoB; imtst mvRim i
I i i mosMHBS ; TBJCB niBiits i
i i i •
I I i »
It 1 a) lot gim 1 a) ft. 04 + or - 0.01 I a) Controls, at blttt 1 eib»o». S.S.
H | b) »ot giv«* I aq/g 1 *) »»ll-t«ri lo* birthMjght, at I Dcvolf*. I.S.
12 | e) Mot glT«B l b) 0.0» * or - 0.02 I tittk 1 1*80
11 I 41 lot glv« I «9/g 1 c) tr*-e«tm. »t btctk 1 »mtrition B»port«
It I •} «ot jlT«m I c| 0.01 « or - 0.01 I 4) Controls, 3 ao 1 Int«raa.tloo»l
10 I f) not 9i»«a 1 •«/« 1 •! rnll-t«rs lo« Birtkmlgkt, 3 so 1 21(3) :3«1-3«9
I |4) 0.«9 * or - 0.12 | ft tr*-t«rs, 3 so I
1 1 «9/9 1 **41ans » ot - SIB 1
| | •) O.S» * or - O.sa | |
I 1 i«/g 1 Konatos In lallfal. fco-Mn froap 1
| I f) 0.22 * or - 0.1* | scan Urtfc*«igkt H80 g. 24-3C rt I
1 I *q/9 1 gcttetloi, l«ll-t«ri lo* birtbnlght I
1 | | group a*an blctk *«l 0.036 ng/g 1 b) Klti pie sderoala patients 1 Bolibecber. J.
1 I aeALans I Sasfles fron 7 scalp sites in each 1 Stuart, B.C.
i i | sabjeet 1 1*7*
III | Clinical Cbenistrr
l | | CltlBl; JOB1TS; CltTUL RBTCOS I 2»(11) ; 1996-2000
1 | i IISTH oistiazs: atn; uoBitoa; i
I i i item*; ciicnjB: cnion»: cop;»; i
1 i i setts Tooiit; BiiemsB: BIIU.SS i
1 i i sitinmit siiTiB: sonoa; soirtus i
| | | 11BUIVB; tlBC I
--,,,-.» - ' ' '
III 1
j j j 1 rerie* ef irarld literatue on the | Jenkins, B.I.
1 | I accaselatioa anfl bioooseeatratlon of 1 1*7*
| | | aelectea toiic trace setals in hsnan | ZTl-«00/t-7*-04*. 1*4
1 1 1 hair «»4 nalln a»4 other saanalinn 1 pp.
| t 1 hair, far, nails, cla«* and hoofs. \
I | 1 Tabalated ri geographic area, I
I I 1 aabjects, sex, age, exposure t
I 1 1 gratiest, analyses in ppn, and I
I | 1 aathoritT free over 400 references. 1
III 1
| | | IIIICl: lOSTIUIl; CMIBl; CIITB11 |
1 i i mild; ruscpE: noun HST: «f i
| | | ttllllO; SOQTB UnlCk; SOITBEIST I
I i t isii: oiRiD KIKDO*: anno sims: \
| | | 1111: milS; BETIEB; 1ITIBOIT; t
l i i itstnc: BoioB; CIDBIOS; CIBCBIOR; i
| | | CQllM; CC??H; »»!; BCTCOBI; f
l ii iicKBit snBinits Tilt Ti»ionnij KB i
1 | | rciirtiof: kilBii POTOUIIOIS; |
I | 1 EICkCCOBIIkTIO*; SIOIBBICkTOBS; tlfl 1
1 i i EOIIOTIOI; vopvimoB zxposni; *un |
| | I tCItlTlOl; ISkCl HIMWISJ HITklS 1
1 1 1 «
(Bin p»oi)

-------
7a»o-SJ-2
t
it* S0.9»i«, BP 1*17 C, B» 3000 C, TP 1 aa Bg  at  22*0 C.  10 aa Bg at 2570 C
                                                                                      (COIIXBOXD)
I
1
1
I
1
1
ItSSWS
•s»«
Hurt
«1«7
Miner
1
1
1
(
EiMsms loan

iBimxcu.
BBTHOD
•1
it
(
l
l
r
i
i
i
1 1
I as*« 1 »
I Lira 1
1 1
1 1
f 1 1
1 1 I
1 1 1
1 1 1
1
1
1
1
imia
or cuss
a) *
M 2
•1 7
hi z
l
l
1
MISE
») O.Ot-0.1* ej/» (»et
»t)
b| 0.21-0.23 ng/J Net
«tl
•1 0.08-0.22 04/9 <»•*
«tj
1 lot glT«»
a) 11 a) lot gl»«n
b) 3 b) lot gitea
I
BUB i 	 	 etiEtii xirotsAiioB i KTMBBCE
! . .»
i i
») 0.09 « or - 0.07 | .) Bales 1 Tofcm, 8.
ag/g (••* «t| 1 IJ Pnal*> 1 S«Mki-raa«K>to, B.
b) 0.22 * or - O.Ot | 1 1BUO, K.
aj/g |mt *t) f fro* * ?roap of 61 Mtop»l«», 1 T«r»l, g.
1 tactmalc ndical «»*ia*tioi*> Jap». 1 1*80
1 Bilu, M» •«• «0.6 tc. Ttralma. \ IrchlTM of
I MU »« 37. • TT. 1 EDTitOlMBial S«»ltk
1 I 3S(1»iJ«-»»
I IB1CI EltBIBTS: JUIOPSIB3; J1F»; I
1 JIDRWHI; 1BSXIC: C1JBHI8: COBU.T: 1
1 cBtonvB: coTTtt: »oi; BIKIBT; i
1 iBentB; BicitsiM: Bueutst; i
l BVBIOITO; imBon: sciroioB: i
1 sntmii: TITUIVV: TIHBIBS; 2i»c.- i
1 C01B; BtOBIIf: IIIEJ4 nOIZTS: 1
1 CIltBtVB: CIHBEUBB; BBllIj IVJCLBSi 1
1 tiBcius: siiBBB; vnest IOBTI; i
I B JlltS; COMIBlTira lTUtHTIO»S; SKI; f
1 MBnsic BinicHE t
i i
U 0.13 * or - 0.05 | •( «»!•• 1 T«k««, B.
•9/7 (••* •') 1 t) I««»l«« 1 Sunki-TamHto, a.
W 0.02 * or - 0.03 | 1 Uaao, (.
»g/g f«»t it) I ttoi a qro«p of «1 »«top«l«», 1 T«r»l. B.
1 fomslc wdlcal •i*aiDttio«a> Japaa. 1 1*89
1 1>1«, M** a«* 40. « Tt. r«ult>, 1 archive* af
1 M«a •?• 37- • re. t C*Tica*M«tal Bvaltk
1 1 3«{1):3t-M
l TIKI rttatns; kmorsitst Jam; i
1 IlgBTBUB: IfSniC; CIDBIDBI COHIT; I
1 cnoaius: ccrrsBs r»o»: BMctar: I
1 1BOIOB; ai«BisioB: stieitist: i
1 IOBIDIDR: IIIIBCBI! SCUDIDI: <
I 3nmvi: TITIVIOB; miDloB: intc: (
1 eoiB: gtoiiM: urn: HDICTS; I
1 CI1BBS3S: CSinilLIB; 9U11; JUSCltS; t
l imctMS: sriitc lotss; »OMI; i
1 «tI«lS: COBMB1TITZ ETIIOMICM; SEI; 1
I 1C1IBSXC SJOICIH I
' '
a| 0.12 » or - 0.07 | a) Bal.a I Tnk«»«, B.
nij/g (>«t «t) I t) !>•»!•> 1 Sazaki-Taavaoto. B.
b) 0.09 • or - 0.12 | 1 »«mo, K.
ua/g (vet vt| 1 Fcoa a gcoap of 61 »top*i<», I tecai. B.
I fcreasic aedlcal ezaaivatioav^ Japan. I 19BO
I BalM. aeaa age «0.« re. r«Mles. I lzeki**« of
| i«a» age 37.4 Tt. 1 iBTiroueiital Health
I I 3S(1»3«-a*
| II»CI ntBEBIS; 10TOPSIES; JlItB; I
1 iimBiB: Msraic; ciosioi: COBU.T: i
| COCBIDB; CCfPZt; IJOI; BllCDIX; 1
I IICKTR: HteilSIVB; B1BS1BISE; 1
1 loexottn; amioti: SCHDJBH; i
1 srusins: -ritinoi: T«»IDIO»: inc; i
1 60I.C; BtQHUf; IITEH; KXDKTS; t
t ClBtBin; CniBEUOB; HX1BT; BOSCLKS: I
I IIBCMtS: 3*UEB; IVBGS; aOllii 1
i B1TUS: COB»UMITS CTHHIT1OMS! S
-------
7««0-«2-2

T

Btl <0.9«|a, m 1917 C, B? 3909 C. T» 1 aa Hfl  at 2290 C,  IO M Hg at 2570 C
                                                                                      fCOIT»1)ED)
ISSBB
4M9
IM*
»SM
Bvael*
»5S1
1*11
wstws ionic


1
i
1IU.TTIC1L
reraoD

*

man
r CISBS
2
j
> •
) 8

I1KX
0.10-0.24 ng/9 (n*t
1
0.08-0.09 »9/9 (wet
)
) 0.03-0.22 ng/g (mt
t)
) lot giT«n

•HI I 8EMU.L nroiBlTIOB | HFESEICE
1 1
1 1
O.t7 * 01 - 0.10 1 •) teles 1 Takata, B.
q/g (««t «t) 1 t) T««»la« ( Snzakl-nmioto. 9.
0.09 » or - 0.00 I | AMBO. I.
g/g («at vt) I »to« • gro«p of 61 aatopsio*, I T«rai, B.
I forensic Mdlcal •xulutioi*, Japan. | 1*80
1 Kl«>, MU a«* *0.( it. Mnl«s. I iccbl»ea of
1 MU »q« 37.a ft. | loTltonMatal B«altfc
1 | 35(1):3<-*«
1 tucB iLinns: IDTO?SISS: JiPii; t
I U»mi; IRSBIIC; CUIXTU; OOBILT; I
1 cnoBtM: coppisj not: nmR: i
I IllIVB; HKIESIVB; BUGUISI; (
I BKIPtVI; iniROR; 9Cim«l; I
I snnigB; tinsinu: nnoiVB: 7i»c: i
I MID; B10BIM: LITIB; KIDIIIS; I
I cHiBioi: cuKBEitoB: aiiBi: IBSCLES; i
I fimtis; seuzi: 10193; lam; i
| BEtkIS; COBPttlTXVE ETU.01TIOIS; SCI; |
I fCSZVSIC BIBICIIE |
1 1
) 0. 12 » or - 0.09 t •) •«!" 1 tnk»a. m.
vq/g {net «t) | 1) T«al«a | Saxikl-Tanaoto. B.
b) 0.11 » or - 0.06 | | anno. «.
aq/9 («et «t) | Itoi a gtatf of f 1 »»topal«a. \ T*ral. B.
1 fot«BSle wdtcal «iaaliatio>«, Japai. I 1980
I Ial«a( M«B *9* «0.* jz. r«ial«a. I Ircfciica of
I *«aa aq« 3T.a jc. | lB»iron»«»tal Health
1 1 35(1):3C-«»
i i«»cs nsims: amofsus: «ni; t
I iiniinii: nsnic: ODBIOB: COBU.T: i
I CJioamst coptci; HOI: BIBCJBT: i
I iitioB; aisiistoa: uieiiuz; i
I iiBioioa: iniBonr: sciiomsj i
1 siinnia t muna: TIUDIHB; trie-. i
I eciD; BSOSIII: ixvzi; nniiTS: i
| Climai; CZIIBCUVB; BE18t; BV9CI.IS: I
1 tiiCBtis; spini; IOKS: iont; i
| AE1U3; CO^PIWTU! IT»10»TIO»S: SZI: 1
1 fciime BtgiciiB i
1 1
1 1
1 1 tnlm el wnia litvratnr* on th« I J«ikl*s. B.«.
1 aec«»alatloi aa4 bioconcentritlon of | 1979
I ««l«ct«4 taite tcac* Mtala IB taa»n | EPl-tOO/*-79-0«9, 184
1 kale aa4 Dal la sad otb*c aiaaalian j pp.
1 talr, f«rf >aili, cl»s and koofs. 1
1 fab«lat*4 tT qvoqrapUc area, |
1 *abj«cta, s«x. aqe* oxposart 1
1 4cadl«Bt. aialTBos in ppa, and (
1 aitkocitr fcca over too r«f«c«Bcea. i
1 |
1 ItXICl: IDS! Bill »: CMlDl; Cllttll \
\ letllCi; SD10PZ; BIDDLE E1S1; III I
I tittin: sooia iBCTici; SOOTBEIST i
I »«»: DTI1TZD (MGDOBi OJTTED STIIES; (
1 BUB: iiILS; tzTin; tmaoiT; I
1 itsmc; BOEd: cioaiaa; cajcnim; i
1 CCBIIT: ccppiB; izii; HIBCOBT; (
1 iicKtLi snciruii: TII; THIIDIBB; ME i
l iciimoi; nniL posoiniois; i
1 ticicco!iTiHT:o»: BIOIIDICITOIS; LIVD I
1 tciionon: rorotiitoB RPOSDBE: 9»tie i
t ECltOTKM; TUCE ZLBBtRS: BIT 1 IS |
1 1
(BEIT PlGE) " "
                                                                                                                                                                                             o
                                                                                                                                                                                             Ln

-------
    Ynafti**
    7MO-«J-2
    »
    itt $0.9*1*, at >9i7 c. B» 3000 c, n i •• 14 «t 22*9 c. 10 u 19 at »T« c

























KSSOI



a. 532
VaBCTMB















•TMSBCT IO*TE
























1 IUTTZC11
B&TBU1*


n




















I «s» n
i
j
i
i
i
i




unit
or cisss


a) 5
b) 2



















) 5
M 3










met



a) 0.06-0.15 19/9 I»«t
•t)
b) 0.11-0.23 «9/9 (Mt
vt)

















a) 0.11 19/9 (»«l «t)
) 0.07-0.23 «9/9 [»at
tl












i
i t
t i i
BI»I | GEIIUt IirOIIinOI
1
1
1
a) lot 9lm I a] Ial«*
til O.IT t at - 0.09 ( t) rntloB
•9/9 (V*t »t| |
I I Eoa a 4toav of 6t avtopfll*3«
1 for*isie Mdieal •xaaioatioaf, Japca
1 B«l*r« •••• ••• *ff.4 T'« 7*>al«s^
1 Ma* ao« 37.4 Tc.
1
1 met nsiins; inomss: JIP*I:
l tiosiuii; itsmc; cumm: coBiii:
f cnan»i cofw: iio*t mcntT;
t XlrXOfl* R1€VX5HB; fltVGftllSB;
i itznivit aniion; scinin;
l sitnrvnu tmitmt nnoias; UK:
1 eciBj tion»: iivn: EIBIITS:
1 cmnn: cnmittii: ism: insais:
I 91BC1H5? SflBHS L^VSS; AOtTft;
I BETU.S; coiriiinn trttniion; an:
I focnstc atcKiis
i
i
a) O.oa » or - 0.0* 1 i| Ulas
19/9 ("t *t) | t) r*ail<*
11 0.1* * or - 0.09 |
19/4 (**t »tj I Itol i qto«> of *1 aitopsl**.
t focmclc aedical •xaBlaatioM* Japaa.
j ••l*a« ••!> «9» *9. < rr. r«ail«*«
t i«*» «»• 37. < rr.
1
1 i»ci tLBBtin: inorsiss; J»Mi;
l itenioi; unite: cisiioi; COJILT;
cncBim; cctnts i>oi; MKOIT:
Mnoi: iinisiiii: uie»tsi;
tOBTDHB: IITTMIT; SCMDIDIi
SI1HI015 TIUHII9: TtlUIOl: tIKl
citmani ctinuiM; EEIBI: BOSCIKJ;
titoifis: silBCi; I.HK3: loiti;
RItUS: CO1PIB1IIIE IflLVltlCIS: SSI;
reimic neiciri
lErnno



Takaia, a.
Sicakl-lamaoto, B.
tauo, t.
Tarai, B.
1 999
Ircklra of
BiTirauatil Maltk
3S(1|l3«-«*













Yikana, B.
laaao, K.
Twal. I.
1980
IrchiT** of
e&ftroiMital Baallk
35{1):36-»»










                                                                                                                                                                                    CO
                                                                                                                                                                                    o
IIICT omrosRioi sitioai 01
I TISS1B
1
1
1
1 *5M
11094,
fllSll











1 nrosmi toni
I
i
l














r tnirricti
I BEIHOB
t
1
1













I iDaia
I OF CASES

*) 10
b| 8
c) lot
9lT«l










I (IMS

*) »ot given
b) lot 9lm
c) Vat 9tr«a











mi

il 16.3 » or - J.»
a9/Jl
b) 9. 1 » or - 1.8
W/il
0] 52.9 « « - ».7
««c« Ticttlf-ciloiie
ttlttttzltlo*, BO Tttuia 1 deficiency
t) S«T«r« fretalc-calorl*
talmtrUloi ui Titttin l aifidancy
cj IcaltbT eettiol*

l*l>o«ri«bed Thai chUiron, aq«<
1J-60 to. Controls. Tkal children.
•9«a 12-sa >c« jaM aodo«c»iK»>lc
t«ctqro«»d M Mlxwrlfkvd.
UlIllID; CBI1D1H: BIOOD PUSH;
•wsiTioiit Bincitian: IOTSITTOIH
B1S010MS: PEOTWS: TITIIII 1:
III IS MS
fBIZI»CI

siith, r.i.
Sasltlod, I.
tliuugtal. o.
tcltTHIE, C.
Gooi**x, t.S.
dlsnf s.r.
1975
iMticai Jottrml of
Cllileal lutrltioa •
iBj732-T3i




                                                                                 (ISIt FtGZ)

-------
ritatio J
tt!03-57-«
ntcr coMosmoi »nora en nvemmtn
                                                                                (COITIIITEBJ
nssni -
aS55
Blood.
aorBB












stposvn mm















iiuRicai
BETBOB















tnsa,
01 C15BS















UKS
*) lot ji»aa
b) lot giT«a
c) lot glv«B
d) lot giMB











MM
a) 28.5 » or - I.I
a«/dl
b) 27. « « or - l.»
«9/dl
e) 2».7 » or - 2.2
no/Si
d| 36.7 * at - 1.6
«g/dl
(S.E.)






GS1I111 XirOtllTIOf
a) 102 Bigrait ekillni
b) 5» boys fnw »>
c) 43 girl* team a)
J) coatrola froa ottoc «tidi«s
35.3* of •) k«d <20 ««/U

}-n «o olds, bclo« 3rd pozeoatilo IB
bt, lit, *«d k«scj drci>f«r«BC«,
cbildcoB of BexicaB-lBoricu far*
•OTkors. Controls, yona.
tlldl«-cla*« ekiUcoi, Colorado.
TITUII 1; CBI1DHI: IRC; UIB;
HOOD niSHl: BMOB SIKH!
ccttnkmi ttitmiois: met
it inns; COIOHDO
nmncE
Cbu*. B.«.
RaBbidgai, I.B.
Baractt, S.B.
Boats- Jacobs. B.J.
Leu, K.
elllospl*. J.
1980
lB«ricaa Jootaal of
CliBlcal Batzitioa
33:23*«-23»»





tine
TI«0-66-«
tl
lt« C5.38, HP «1«.S C. BP «•« C, TP 1 n Bg at ««T c. 10 BB Eg at  S40
TISSOB


»5C
dc«Bal
alaBd












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Ill 1 r»roT«. 1.
1 1 | Jain*** ior««r, tS rr old, at 1 Bcskizaia, K.
II | client* FtodociBO Blast tor 30 yr. 1 1980
1 | | Diad at aaxillary and Inm caac«r. | Xatvrutioul archives
1 1 | Controls, 54-71 yr ell. 1 of Oceapatio*tl and
III 1 ziTlKMueital Malta
1 1 1 91(11; 1BXPO3I TISSOB; 1O1T1; SOBJ I «:t«t-I50
I i < aisioB: iBiii: cisun-Lna: CHEWOH; i
I i i xiajZTs; HTM: WBSS8 ECSCLXS: I
l i i HBCBHS: SKI; cBtonvi: carpet; i
1 1 1 BIT US: II»C; IIBDStBIll tiirfS; |
1 I I muiTiai: cccvMTiam suiiDS: i
1 i i ECPOUTIOI inosnc i
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1 I)} lot iriMa | ug/g Hb | t) Irytkioeytu. 1C T-12 10 ali* I 1980
1 e) tot glrea \ b) 27.6 t ot - 3.6 | c) ot jlT«n | ag/g Bb | 4) Erytkraeytea, 21 I1-t5 yr o!3» I Bedical Sciences
1 | I •) >ot glrra 1 c) 37.* * or - «.« 1 •) Irytkrocytu, 52 ad:7-13
f 1 It) »ot J!T« | ug/g Ib I () utakaeytM, « «-10 yr all* I
1 f f 9) *<* gi»« 1 4) *2.3 * or - «.2 | q) uakacytt*. 1* alolts 1
1 1 1 «g/9 Hb | |
J 1 •) «2.2 * or - 5.6 | (taltky »abl«ct». 1
J | ag/g Ib I 1
J 1 C) 0.093 * or - 0.022 I HIC; lOULTS; CBZLOan; J1F1I; 1
1 i noyio (B*7) c«iia i amis: BLOOD PUSBI.- isTTSjocrris; »
1 1 9) 0.129 * or - 0.03} | ItVKOCntS: 1SE |
1 1 ug/lO(E*7) nllc | 1
....... i 1 i
1 1
«S a) 13 •) »ot 9lT«« a) 79.5 « or - 13.6 | a) 1-« ma old I Ushl, I.
M 21 b) »ot gt»«« n 21 c) av»t glT.a bl »*.» * or - 17-» I ej IT-IS yr eld 1 Biroshlaa Jotrnal of
f d) 52 «) lot gt»« «q/dl | d) Walt* | Rcdleal Sciences
1 01 101.0 » or - 22.6 | | 29(1):7-13
1 ng/dl | Malthy aablccta I
1 J d) 9S.9 * or - 18.6 I I
1 1 na/dl | TIIC; 1BOII5; CfilLDSIJ; J1P1»; |
i i mils s sioo c ntstn anttocmst i
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» i « i
1
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1 b) 60
1
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1 1
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1 b) (0.8-1M.1 ia/100 al | no/100 •! | t) F«iJ«nts at follatfl area t Roela, B.
1 b) 77.2 * or - 2.1 | | Bernard, t.
1 04/100 al | lain, uai aoc *2.3 yr, froi I B«ck*t, J.P.
f (S.S.J | C 9* »iomt children 1 Clias*, B.P.
b) lot gtT*i 1 ag/dl | t) 53 boys fro* a] I Baabia^e, K.I.
e) lot glT«* | b| 7«.3 » or - 1.6 t c) *1 girls fro* a) I B»cn«tt, S.I.
i) lot gtnn I ag/'Jl 1 4) control* fro* other atallcs | Hoots-Jacobs, B.J.
( c) 7t.« •> or - 1.5 | fypozlacMia (<6« a
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85.7 si/100 •! | area)
89.9 nf/100 •! I t) leaideat* of Bn«Mls (!•*•
onetcic I fcllvtal ar«»)
1 c) Msltoat* of Chaclsroi (control
1 it««)
1 Korean* vitfc aa acctmlatlog of C60 ir old.
I t«ta««t« of the >aM areaa 35 rr.
I l«lfi«i
I
I Birsiaa: mows; \st; BLOOD tnsai;
I mis; c»ama: mo; BMC DEI:
1 Bfins; «ic; ttDvsniti mssiois:
1 iiDusrniii jcttntioij POPOLIIIOI
1 11SOSOSB; DBB» 1BEIS
1

1 Baric*, irofil* of healthy nblects.
1 Bastllm data fox tetenlalng ehaages
1 li Bitritional itatu fro* indastclal
1 {cod pneesitgg t*ctniqn*s.
1
I in XEU»D; u>m,TSi tens; xifurs;
I HOOD ssunu: smij KIDKTS: UTIB;
t Bill: ISTltl; DIRS; TOODSi SOILS;
1 TietitTiai; CURIOE; COPPIS-,
1 Biieinst: imis: TSICB Eirastts:
1 K1C
i
t
&) 1.44 * or - O.OS | a) Itanaai Citr. KS, karl-««t«r axea
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b| 4.28 * or - 0.82 | slwlflcantlj loner lenl cr<0.01) 1m
aq/lg 1 kat4-«ater area.
t
1 KS and no reildeata aatched foe a?e
1 (ceaa aaes 37 and 37.7 rr), MX,
I Icaotn of resldeaoe, aarital aad
1 ccoooalc itates, occvpation, mtber
1 cf cklldrea. saoklaq habits, at. vt.
1
1 ta hacd-natec acea. «l«j«l£icwt
1 iicrease in brpeiteBtloa. ICC
1 akaor>alltl«t« aad bTPcroriceiia.
1
I tllStS; B1SSCOBI: aDOttS;
1 omnoTiscnm DISUSES:
1 Biintnsioi; BLOOD SHOB:
t ccBMimvs mioiTiots: CIOIIOR:
1 cucio!: CEBCBIVI: LITEIVB;
1 HGIISnB; tSOSFHOSODS; rOUSSIIR;
1 50DIDB; II1C; BfOtCcmOLaTIOl;
I cmncns v«Et

1
a) 113 » or - SO I >) lea, lo» tlood prea*ace
»j blood fresanre
og/»l I taafc tcoa vmloes atojj. a«tlaat«d
1 dallr dietary Intake 4.5 a?.
1
t Polynesian icsidenta of Vokelan
1 Iflands, crovded condltloaa.
1 (nceiateiee eooaoar- lea, *eaa a«e
1 45 jt, aeaa fct 1C7 ea, aeaa « 74 k«
1 (oaea, a«ao a«e «* rr. aeaa bt 165
1 ca, aeaa vt 79 kg..
1
1 COPPEB; Zinc; BIOOD SSBOHi BUB;
I «IILS: mint
- - . t
(BEIT P»SB) ....,.,.
HfEEEICE


0»ls, B.I.
anerys, B.B.
ncaet. J-P
Bernard. 1.
«ei
EmTlcoBaeat&l Beaeaceli
24:117-130












Gotbcie. S.B.
Coblnsoa, B.T.
1178
leu Zealand ledical
Joacaal $7 (603): 3-8








llereabaaa, a. L.
Tlelscaaaa, I.I
Dmn, 3.
Inoli, J.
1975
lancet
1(HU): 1008-1016


















RcKemie, J.B.
GBtkCl*. I. I.
Prior, I.a.B.
1978
iaericaa Joernal of
Clialeal latrltioa
31:422-42)












                                                                                                                                                                                          o
                                                                                                                                                                                          v£>

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1 1 1
II I
a) lot glT« | *) 10.« «g/o w»t rt f •) *ork«r I By»do. K.
b) 1.9-12.5 nj/» nt «t 1 b| lot gi»«« | t) coitcol* 1 Saioki, 3.
1 1 1 tmcmjt, I.
1 1 Japa»*M worker, 65 yr old* at 1 Bcshlzate* K.
1 1 ciroiat* crad«cl»9 »la«t fat 30 ir. 1 1*«0
1 1 Bled of aailUarr a»d la* caacer. | Zctenatloaal archive*
1 | cettrol*, 59-7i ft oia. 1 of Occip«tiOMl tnl
1 1 1 «BTitO»»«»t«l HMlth
1 1 JJtM; HIIPOS1 TI3SUI; lOXTt; SOfB I «:!«!- ISO
f | nlCO*; (1111} CREIKIM; CMEI808; |
1 1 IIDUtS: 1ITSB; MISS; BOSCtIS; I
1 i tncsm; sue cKonoi; CCCPEH i
1 t tiriii: tile: inosTim. PURS: i
1 1 IlllUTICt; COCITPtTIOlU, BltllKS: 1
1 i tcFiunoi txrosns i
i < i
1 I l
•) 8.4-1T tg/g (Mt «t) |i) 11 » or - 3.0 ng/g 1 •) Balm. c«»bt«a, t mbjcets 1 Tifca», a.
b) T,*-9.2 »V9 (o*t «t) 1 (»«t «tl 1 t) r«iali«. content, 3 «b}«ct« I sazaU-TMUoto, s.
c) 9.7-17 tq/f (nt it) | b) ». « « or - 0.9 I c) B«l«, c«r«bell«», C mbl«cti 1 liuo, 1.
9) 7.8-22 wi/g (mt it] | 19/9 (mt irtl 1 d) M»l«i. CKclMllm. • <*b-j«cti 1 T«»l< R.
1 c) 13 « or - 2.S og/tutloi>« Japac. I Eavlroncmtal B«alth
1 (*«t "t( | lalva. ma« »ij« •». 6 rr. F.MlM, I 35(1>:J«-»«
1 j i*a> aa« 37. t fc. |
1 1 1
1 i Tucr nsiEiis; tirotsissi JIPII; i
1 i naarna: nsaics CIBBIOB; COBUT; i
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l i nrioB: Bieftsni: a««s»«tsz; i
1 i i»»ioii7«.- i»ii»o»r,- scjnign; i
l i auBiius: iiunn; UUDIHIS UK: i
1 1 S01D; BIOBIBI: LITE1: KIDtnS: 1
I i ctKssm; criiBiiiffa: RIII; IBSCIJS; i
1 | EtICBIU; SPIKI; tOWJS; 1OBIH: I
1 1 BIHISi COBMSITITI STIWITICBS: SIX; |
1 1 FCItrSXC BtOICIBB (
II 1
a) dot glm I a) It.* ag/g | a| tor tec - nnbcoa (occipital) f Syoio. (.
b| 11.0-12.* aj/« | 1| lot »ir«» | I) S caitroli - cerebral (frontal) I Small, S.
c) lot aiT*» | e) 13.5 aj/f I e) lorker - cerebellM 1 Foray*, I.
d) lot giT*B I i) U.O ag/g | d) 1 coatrol - c«c«b«llaa I Mialzaka, K.
1 r«t «t ( | 1910
t 1 Jipan««« «ork«r, 65 rr old, at 1 latenttloatl trchlTM
1 1 cbroaat* trodaclat pltat for 30 rr. 1 of occupational and
( 1 tl«d of nzlHarr *ni luv cucor. > CaTlroueatal Hvaltk
1 I cc.tcola, 5»-7» jr old. t M: Id-ISO
1 1 1
1 1 JIP1B; ID IPO SB TISSOZi 1OST1; BOO 1
t 1 eUBOl; BBlIi; cnCBEUIIHi CmEEtVI: 1
I i KIIIETS: lira: HISS: aasciis: i
1 i dictns: sun; cnonoi; caifti; I
1 1 »R1U: tltC; IMOSnlU. PtIBtS: 1
1 I 1I»»UTIO»; COCVPITIOIIL BIH1BS; I
l i termiTioB EIPOSOBE i
i i i
1 1 1
ot gi»« | «.» ng |(1 s«ipl«d at rat* of 1 1/aia, 2-10 f UselBson. E.e.
1 1 all aft«c baral«« * arc »«lalag rods. I 9«n*del««r, 6.5.
1 1 1 Johausog, T.B.
1 1 Oal»erattj phfiics shop, Florida I Vlocbeater, J. «.
1 1 1 H7t
1 1 FIOHDU UBITS; BRUTE; CaLCIOH; I linal* of Occupatlonsl
1 1 ctLOBiit; CBXORIDB; copisi: uoi; I iTgleac 19:225-238
I I mo: alienist; ncicst: MTISSIUB: i
1 1 SOIFOJ: TXT1IIVR: TM1JIDS: XI1C; aXC 1
1 1 polnnioi; mats: iiraasTBiii. \
i \ IYBOSMBICS; nkct xurans i
i i i
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-------
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7100-66-6
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t« 65.38, HP 419.5 C, BP 908 C, vp i aa Bg at 487 c, 10 aa Bg at 590
(CORTIROED)
TISSUE
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OF CISBS
a) 16
b) 22
c) 13
d) 11
el 15
f) 22
g) 10
h) 18
i) 13
1) 3
kl 7
1) 12


.












a) 23
b) 19
O 42

e) 26
O 40



















a) 17
b) 17
O 30
d) 30





BIRGB
a) Hot given
b) Hot given
c) Hot given
d) Hot given
e) Hot given
f) Hot given
2) Hot given
) Hot given
i) Hot given
fl Hot given
k) Rot given
1) Rot given















a) 108-190 og/g
b) 120-357 ug/g
c) 108-357 ag/g
d) 103-194 ag/g
e) 139-318 ag/g
f) 103-318 ag/g



















a) Hot given
b) Hot givei
c] Hot given
d) Hot given





BEIB
a) 218 or - 9 ag/g
b) 225 or - 9 ag/g
e) 200 or - 32 ag/g
d) 225 or - 16 ag/g
e) 232 or - 22 ag/g
f) 225 »r - 296
ag/g
gl 105 or - 37 ag/g
h) 245 or - 52 ag/g
i) 140 or - 49 ag/g
1) 260 or - 87 ag/g
k) 180 or - 41 ag/g
11 175 or - 118
ag/g













a) 150 ag/g
b) 167 ag/g
d 161 ag/g
4) 145 ag/g
e) 168 ag/g
ft 166 ag/g
ledians


















a) 216.2 « or - 43.2
ag/g
b) 239.7 * or - 108.5
ag/g
O 181.6 » or - 31.4
ug/g
d) 235.2 » or - 47.2
nqSa
Mysy

G8IIB.U I1?OBHATIOB
a) Controls, at birth, aales
b) Controls, -at birth, females
c) Fall-ten low birthvelght, at
tilth, aales
d) Fall-ten low blrthveight, at
tirth, feiales
«| Pre-tern, at birth, nales
f) Pro-term, at birth, females
g) Controls. 3 BO, Bales
h) Controls, 3 BO, females
i) Fall-tern low birthvelght, 3 aa.
tales
1) Fall-ten low birthveight, 3 ao.
females
k) Pre-term, 3 ao. Bales
1) Pre-term, 3 ao,. females
lUdians » or - SB
Reonates in Balifax. Pro-ten group
mean birthvelght I860 g, 26-36 »k
gestation, fall-term low birthveight
group mean birth weight 2371 g, 38-42
«» gestation, and full-tern controls
mean birthveight 3590 g, 38-42 vk
gestation.
aaiB; amis; ZIBC: COE;EB;
BIRGME3B; VMaDIDB; IODISE; IHPaHTS;
SIX
0) Rale controls
t) Peaale controls
c) 111 centrals
d) Dale tnltiple sclerosis patients
e) Teaale multiple sclerosis patients
<> 111 an It 1 fie sclerosis patients
Samples from 7 scalp sites in each
sab ject
CHID*; igaits: CKBTHIL HEBVODS
STSTEB DISUSES; HUB; alOHHTOB;
BBonuB; catena; CHLOBIBB; COPPEB:
8CID; IODISE; BIBOaRZSB; RBTalS;
SHE", Til: SI17EB; SODIOS; S01FOS;
VI»»DHJB: lire
levle*. Profile of healthy subjects.
Baseline data foe determining changes
in nutritional status from industrial
(aod processing techniques.

RIB tBIlIRO; IDOLTS; FBTOS; IR*1BTS;
BIOOD SEB0I: HUB; KIDIBTS: IITBB:
RIIK; BSVIEl; DIRS; FOODS; SOIIS;
?tORITIOR: CtDBIDBl; COPPBB;
BIHGaBBSB; RR11S; TBICB E1EBEBTS;
me
01 Bothers of infants with scina
tiflda
t) Infanta vith spina bit Ida
c) Control aethers
d) Control infants

Hevborn with cystic spina bifida. and
Bill): ZIRC; IHFIBTS; PBBGHIHCT: TBICE
IIESBBTS: GEBHIHT
BBFBBBBCE
Gibson, B.S.
Dewolfe, B.S.
1980
Bntrition Beports
International
21(3):341-349





















fiyan, D.B.
Bolzbecher, 3.
Stoart. D.C.
1978
Clinical Cheaistrv
24(11) : 1996-2000








Gathrie, B.B.
Boblnson, R.F.
1978
Rev Zealand aedical
Journal 87 (603): 3-8






Bergnann. I.E.
Hakoseh, G.
Te«s, S.-H.
1980
laerican Journal of
clinical Bntrition
33:2145-2.150



-------
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»*» 65.38.
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1 b| 13
1 c) 17
1 n 28
1 el 14
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1 b) 12
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1
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1 *) 15
1
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1
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I b) *ot given
1 c) mot givem
1 d) lot givem
1 e) mot given
1 f) mot given
1
1
1
1
1

t ,
\
1 a) lot given
1 b) lot given
1
1

1
1
1

1
1
1
1

i
1 a) Bot given
1 hi lot given
1 cl lot given
1 dl lot given
1
1
1
|
|
1

|
|
|
1

|
|
|
1 «1 7.0-43 og/g
1 b) 4.9-25 ag/g
1
1
1
1
1
1
1
1
1
1
1
1
t
1
|
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1
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1 SE»I
1
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1 a) 138. « * or -
I ag/g
1 W 159.1 » or -
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1 c] 108.2 t or
1 ag/g
1 4) 164.8 » or -
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1 e| 106.1 * or -
1 t| 121.7 + or -
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1
I
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1 ag/g
1 b) 130.7 * or •
1 «g/g
1
1
1

1
1
1
1
1
1
i
1
1 a) 259 » or -
i »g/g
1 b| 241 » or -
|c| 163 * or -
1 d) 144 » or -
1
1
1
1
1
1
t
1
1
1
1
1
i
1
(*«t »t) I a) 24 « or -
(vet »t| | <««t vt)
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1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
(BHT PISE)
1 EiituL intniaTioi
1
i
l
64.1 1 a) 6-11 mo old boys
1 b) 6-11 mo old girls
98.7 Id 12-23 mo old boys
1 6) 12-23 mo old girls
- 47. 0 t e) 24-35 mo eld boys
1 t) 24-35 mo old girls
13.0 |
1 lav Income ccsta Bicaa 6 eto-4 yc oils
47.7 |
| IIBC; COST! Elca; CBILtSEl: KPUTS;
50.7 I iraiL UBaS; B»IB: SEX; TfilCE
| EIRBEITS
1

5.3 | a) aigramt children
I t| Controls Iron otter stmdiea
• 8.3 | a) and b) differed n<0.001
1
1 2-69 BO olds, belo* 3rd percentlle In
1 ht. 
                                                                                                                                                                                            U)

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It
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i) 1682-7000 ppn
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b) ».«-«« ag/j (vet «t|
















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ItElB

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b) 3920 ppn
ol 25 11 ppn
« 3551 ppa
ish vt










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(vet vtj
b) 33 • or - 20 ug/g
(vet vt)














al 3*. 8 ng/g vet vt
b) lot given













f»GE)
GfltUl IVFOGI1TIOI

a) 17 cancer patients
t) 58 non-cancer patients
c) 10 non-stokers (never saofced)
i) S snokere, 1.5 packs/day

««topal«s free hospitals It Sorth and
South Carolina. Blacks and
Caucasians, (dulls, ages 16-91 yr.
Children, ages 4 4ays-6 vr.
SITUS; BOHtS; 1ITSB; KIDBSTS;
RtVtlS; CHTIDEES: CJDSIOB; ?I»C;
l»0; SOBTH CJS01IM: SOOTB CJBOTIS1;
intopsiES; Gioiccmotinoi; BICUL
STUD IBS; «5B; SHOICUO: tOBSCCOS: SEI;
>fQ PltS IS
a) (tales
t) resales

Fros a 4roap of tl a at apsis s.
forensic redlcal exaiinations, Japan.
Bales. M» age 40. t Tt. Females ,
•ean a
-------
ZlBC
7MO-66-6
tn
ItB 65.38, HP (19.5 C, BP 908 C. TP 1 •• Sg at  «87 c.
                                                       10  •• Rg *t 5*0
                                                                                      (COBTIBIED)
1ISSBE
«586
Mdnay
a5«7
Kidney
•588
Liver
»589
linr
ztosoBB BOOTE

•gestion


IBUnlClI. |
BETHOD
S

US
Bl
BDSBEB
F C1SES
8
9
12


a) 8
b) 7
MICE
1S-»7 «g/g
19-55 ug/g
17-* 2 »g/g
t «t

a) lot given
b) lot given
c) 3220-12850 ppn
d) 720-5800 pp»
lab «t
a) 37-180 ug/g (net >t)
b) 17-91 «g/g (vet ¥t)
•Ell | 6BMB11 IBPOBfllTIOB | BFEBEBCB
| 1
t 1
25 ag/g 1 a) Controls 1 Bruno, D.
32.5 ug/g 1 t) "orter group I | Bordberg, G.
25.0 ug/g I c) locker grew II 1 Bester. P.O.
et «t I 1 1980
edians I leeeased refinery »»d sselter I Science of the Total
I letters, aqea 55-76 yr. exposed to 1 Kmrlronnent 16:13-35
1 i«»»y ratals 1-3 decades. Use 1
| tstMea retirenent and death 0-1.5 yr I
1 it qro«p I aid 2-19 rr. gcoop II. 1
I Controls, agts «3-72 jt. wko lived 50 1
j III troa the factor?. S»«d«n. I
1 I
I SIEON: ciDitns; KNITS: LITEB: I
| IBBGS; COIPlBlTItB ET11BHIOIS; I
| IBOOSTlIU BTCIBBB: BBlSIIlSBBBt 1
| IRBODS: 1RIIOIT: 1BSEBIC; 1
1 muraim; CIOBIVB; cismH; CBBOHIOR; t
1 cceiit; coppn; SOLD: IBOB; i
| IIITBIIOB; 1119; aiBGlBBSI; BEBOJBT; I
1 BQITBDBBOB: IBOSPH01DS; BDBIBIOB; |
I sciBEioa; SIICTIOS; SIITIB: 111; i
1 T01GSTM: tIBC: BI11TI H121SOS: I
| IBDBST1I11 PtlBTS: SSEITIBS 1
| •
| twriev. Profile of healthy subjects. I Gnthrle, B.S.
1 Baseliae data for detersinlig changes 1 lobinson, B.F.
I la ntrltioial status troa Industrial I 1971
j teat poisoaing techniques. I Be* Zealand Hedical
| < Journal 87 (603) -.3-8
| BIB ZE1L1BO: IDOLTS; 'ETtJS; IBF1BTS; I
1 BIOOD SSBOB: Bin: HIBIITS; IITSI; i
| BHK: SBTIIB: DIETS: FOODS: SOUS; I
1 tisn»iio»: cuBina; coppii; i
| B1B61BBSI; BR1I.S; TMCE ElEBEBTS; I
I ZI«C 1
| 1
I 1
a) 5063 ppa | a) 17 cancer patients 1 Hanser, D.I.
b) *120 (pn I b) 58 nan-cancer patients 1 Caloeci. l.T.
c> 6068 ppa I c) Two 10-19 yr olds I Basselblad, T.
d) 3297 ppn I 4) Three 30-39 jt olds I Vllllaas. B.I.
ish «t | 1 Piakerson, C.
| latopstes free hospitals In Borth and | 1973
1 South Carolina. Blacks and j Journal of Occnpatiosal
I Caucasians. Idults. ages 16-91 yc. 1 Bedicine IS (12): 956-963
I Children, ages * daya-6 yr. 1
1 1
| ClTltS; BOBSS; LITEB; KIDBITS; 1
| IIOITS; CBItCBBB: ClDHOBi 2IIC; |
| HID; BOMB CUOIIB1; SOBTB C1BCLIB1; I
| ItrtOKtES: BI01CCHB011TIOB; S1CIU. 1
| SIOEIES; 1GB; SBOKXBG; TOB1CCOS; SEX; 1
| HOPllSIS |
1 	 - I.,
I 1
a) 97 » or - 59 og/g I a) Bales < Tulcana, fl.
(let «t) I t) Fenales 1 Suxnki-Iasnnoto. fl.
b) 50 » or - 20 ug/g | 1 Inano. K.
(«et »t) | fret a group of 61 autopsies. 1 Teral. B.
1 forensic sedieal ezaslaatioai. Japan. 1 1980
| Bales, aeaa age aO. 6 yr. Peaales. I IrchiTes of
j scan age 37. a yr. t Ea*lroneental Health
t | 3S(l):36-«a
| ItlCI SLI8I11S; lOTOPSIKS: J1PIB; (
1 noaiBn-i; itsEBic: CIDBIHB: COBIIT; I
1 CBBOBina: CCEP^B: IWB: BtBCORr: |
| IIDHl; RICBISIOB: B1BG1BZSE; 1
1 BOBIDIUI; 1BIIBOBT; SC1BOIVB; I
1 StlEBIIB; TIIIBIOH: flBlDIVB: tIBC: I
| GOLD: BBOBIEE; UTEB: KIDBIIS: I
i ciimoB; csBEBEiinn: BEIBI; BUSCLES; i
i iiiciEts: sptEEB; mas: IOBTI; I
| BITltS: COilPlUTITB 1T11O1TIOBS; SEI; (
| ICtllSIC BZIICIBB |
1 1
                                                                                                                                                                                            u>
                                                                                         (BZIT

-------
tl«e
i«ao-«6-6
t«
It* CS.3*. BP »19.S C, BP 908 C, n 1 n «9  at 487  C.  10  n 89 at S90
                                                                                      (COBtlEBID)
1
t
1
1
1I3SDI
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liver
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1 »s»2
lint
1
t
•5*3
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1
1
1
r
inosm Boats


leoeatioo
1
1
1


mimcu
BBTBOD
us
us
1 i
i
i
n
B9BBH
or c»s
«) 1
b) 5
•) 8
M »
c) It

•1 3
W 2
B1BSE
*) lot 9lT«»
b) (2.0-107 og/9 mt •
a) 30-99 a«yg
b) 22-103 «a/»
0) 19-15* ««/9
Wt «t

t) ».3-12 B9/9 («et »t)
b) 10-t6 eg/o (vet >t)
m« i "eiaiiu nrosBuioB I EsreBEBcs
i :
i i
at 123 «9/» Mt «t | •) torter 1 Brodo, E.
b) lot firm 1 t) Coatrola 1 SateU, 5.
I I furor* . *.
1 Jaraaese iiocler, 65 TT alt. it 1 Reaklzaka. E.
1 cbronte rrodaclao. plait for 34 rr. I 19(0
| ti«4 of uxillacr u< luv cue«r. 1 tit«r*«tioul lrchiT«
| ceittol*. S9-7C rr ol4. f of Oce«pttioiial *ti
1 | EnlroiMittl B««lth
1 J1FH: IDIPOSB Tijsnt: IOITI: ton I <6:i«i-iso
1 8IEIOI: BBUI: CIUBXUOI; CEBEEEffE; 1
1 VIDIEYS; LITEB: VIKSl RVSCIZS; f
I HICBE13: SKII: CEBOUIM; COPPBI: |
| «!IU3: tlKs IIDBSTSIIL PltRS; (
I IIB1UTIOI; CCCDPITIOIU. B1Z1BBS; |
1 ECrntTIOB tlfOSOB! |
1 1
1 1
a) (1.0 tj/9 1 a) Ceatrol* I Vrna, D.
b> *?.o 09/9 I t) Voclnc qroap I I «or4b*r?;. C.
c) 66.5 ag/9 1 «) «ort«c qraap it 1 »e»t»r, P.O.
let «t 1 1 1»80
Icdiau 1 t«Ms«4 c*f inerr asi «a«ltar I Sclme* of the Total
1 tartars, a9«« 5S-7S rr, axpaovd to 1 Bnriroamit 16:13-35
1 k«a*r a«tali 1-3 4« limd $0 f
1 k* fcoi tke faetorr. S»«a«n. 1
1 1
1 sitcM: ciDitEis; rnmrs; IITEB; i
1 miss: cogeuain irnajriois.- i
I UEOSTRIil KtSXZIZ: 8U5VEiaZIT |
| IRBOOS: tBTIIOBT: IRSSHC; |
1 TitLinm; ciEmioi; cisitra; cHsoaion,- i
1 ccriti: coppu: eoic: itots I
I Liimmrs: tun: DIISJIESB; BESCOBT; i
I BCLrBOESUd; fBOSPBOBBS: DOBIEIUS; I
1 sciBDini; stunos: 511 TIB; m; 1
I m«5STB»; UK: Stiffs SlZlSfS; |
| IIOOSTtllt Pt»»TS: SR1TISS 1
1 1
i 1
1 f«»l«». Profile of k«alttr «biects. I Gatfcrla, B.I.
I fascllM data for J«t«riinlBo ekame* 1 Robinson, n.r.
r la aatrltloaal «t»to» froi imlattrial I 1978
I feed pol«oata« t«chni7o«». I >•> Zaalaid aedical
| | Joaraal 87(603) :3-8
| Mt ZEU1EC: iOOlTS: MTDS; IVrlBTS; |
| tlOOB SStttHS Hill; IIOKIS; IITIS; |
I iltlt; ttriTS; BIBTS: ?OOSS; SOUS; 1
I fterritioB; CJDBWS: COPPU: i
I BIIClIESt; inal5; IB1CE IIZBEITS; 1
1 tllC 1
1 t ,
1 1
8.5 » or - 3.8 fa) f!al«s 1 lokava, B.
g (vet «t) 1 t) *eaal«E 1 Sanki-Taaaaoto, a.
13 < oc - 1.2 ig/g 1 t laaoo, E.
t «t) 1 rroa a group of 61 agtopslas, I Terai. B.
1 fervaslc aedical exailaatloi*, Japan. 1 1980
1 Bales, «eaa aoe »o. 6 rr. Feiules, t irckivea of
1 ie» »
-------
Mac
74«0-««-6
»t« S5.3B, n »1».S C, Sf »0a C, n> 1 •• Hg It «87 C.  10  »  Sg  at  590
TISS03



»59»
laag



















595
Ivag





















•MS
lilk










tosnt tons















































lagaatioa








intTTIOL
BsraoD


us




















us































1
1
I
IBim | B1KB
OF C15IS |
1
I
1 a) lot givea
1 b| 10.0-13.7 ag/g
1 e) lot glvea
1 d) 12.0-19.1 ag/g
1 a) lot given
1 « 7.5-1J.1 ag/g
1 »et vt
|
I
1
1
1
1
1
1
1
I
1
)
1
1
a) 8 la) «.»-2» og/4
b) 9 | b) 6.2-16 ag/g
cl 11 1C) a..?-* 15.3 ag/g
1 Wet vt
|
1
1
1
1
1
t
1
1
1
1
1
1
t
|
1
1
1
1
1
|
1
1
1
1
1
1
1
1
1
I
Kilt | 6BI1UL XIFOIBmOl
1
1

) 8.5 ag/g | a) lorkar, right apper lobe
lot given | 6) S eoatrola, right upper loba
13.3 ag/g | c) Vockac, right aidtle loba
i Hot given 1 d) 5 coat roll, right aiddl* lob*
) 12.8 ng/g | •) (orker, left lover loba
I lot given I f) 5 coatrols, left lover lobe
at vt |
I Japaaaaa varkec. 65 Tt old. at
1 chroiat* crodveiag plait for 30 yr.
I Clad of aaxillary aa& laag cancer.
1 ccatrols, 59-7* yr old.
1
| J»ll; aDIPOSS TISSUE; 1OET1; BOIE
| RIMO«; IB1II; crBEBEHOB; CIBIEBOB:
1 IIDRIS: lltM; IVIES; BISCLIS:
I f»Ct.
Snzaki, S.
»roy», 1.

1980
lateraatioaal archivaa
of Oceapational aad
tBTiroaaaBtal Bealtb
act 1*1-150












Brnne, 0.
aordberg. e.
Vaster, P.O.
1990
Sciaace of tba Total,
BaviroBMat 16:13-35

















Gnthrie, B.B.
Bobiaaoi, a.r.
197«
lev taalaid Radical
Journal 871603) :3-8







(HIT PISE)

-------
Mae
7MO-««-«
fa
ttf «S.3». n 4T9.S C.  B» 90* C, TF t M la at »»7 C. 10 aa So at 590
                                                                                     (commtD)























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Bascle
t
1
1









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f
f



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1
1












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I
















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1
1







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i
1
1
1
1
1
1
1
1
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9
1
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1
1
1
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us




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1
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1
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1 «
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b) 11














b) 17 | I
c) 19 <
a is t












-
	 Hisi 	
!

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b) 11-72 ag/g |*et at)













nil i GEMUL nroiimei i nmiici
l l
i i
S1 » or - 1» ' '
(»rt wt) | t) resales I Sn»ki*Tiraaoto, I.
b) »S » or - 25 ag/g 1 | tnano, I.
(rat *t) | froa a groap at 61 aatepdea, I Terai. I.
1 foreaaie neUeal exaniaattoaa, Japan, t 1980
1 Bales, aeaa age *O.S yr. resales, I IrckiTes of
1 aean a«s 37.« yr. I Environaantal lenltn
1 1 35(1)53*-"
l TMCE tanns; tnorsnst jun; i
1 HOBnOT; 1ISEIIC; ClOSIM: COBUT: |
t cncBTKB; comt: itoi; incnr: t
1 iinnB; msusioB; uieiiissj i
1 laiiBint; iniBorr: sciniii: (
l snnxm; Tntiira; nitBim: nic: i
1 COIB; Btoaif!: urn: noiiys: i
1 1 CIII»n«i CntBEUVI; »ltt; BBSO.es; j
l l EIICIIIS; sttxas wmss-. iciri; i
l l intis; coaritiTin zrutrtTiois; SET; i
1 TCIIISIC BIBICIIE |
	 . — . 	 1 1
lot given 66.0 ag/g »et »t 1 | |Todo, X.
1 1 Sasaki, S.
1 Japanese eorker, «S yr old. at 1 raraya, 1.
1 ckroaete srodaclnq pltat for 30 yr. 1 ResUzvka, I.
1 tie*, of aailllary aad lang cancer. 1 19S9
1 1 tateraatioaal Irchives
1 Jim: IBIFOSB Tissue: IOST*; tout 1 of OccaBatloaal and







a) lot given
b) lot given














lot given
>) lot giVM
•) lot given
) lot given













1 BUBO*: mill: cnn»lltr»: cmaoii 1 laTiranaeatal Baaltk
l iiDinsi urn; vnest iirscizs: i *»:i*i-iso
1 tiiciitst sm: CB10M0B: catitt; t
1 BIT US; IIBC: IIDOSTSIU »U«TS; |
| IHUtTtOI: OCCOmiMlt lltUBS; |
i tctmmo* Hposnir. i
	 i i
» 1M » or - 75 pps I a) (oaan | Jtanabrocki, s.l.
W 153 » or - 68 ppa | t) lea | Kantbrocfci. J.I.
3ry »» 1 I«rt tkoab | Greco. J.
1 llso rerievedt knmn levela 30 other 1 ICaplaa. t.
t eleaeats | oester, I.T.
f 1 Brar. S.s.
1 taalthy 20-60 yr olds | e«staf
-------
 time
7»»0-S6-«
It
Itf tt.39,  IP 419.5 C. BP 908 C, fP 1 M 89 at M7 C,  10 •• !« «t SM
                                                                                   tcomim)
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Patents
a«02
Pancreas
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Piervsx
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HUTTICIt
BTTBOO

IS
US
us
r ctsss
7
3
aj 1
) 5
a) 1
b) i
a) 1
M 5
JMCI
1»-«3 ng/g (Mt etj
32-*0 ag/g (vet »tj
1 Bot given
1 2t.1-*l.a tg/9 »et vt
a) lot gin*
B) 15. 7-22.7 »g/g vet vt
a) lot given
b) 5.1-7.9 sg/g Mt lit
Mil | 6SBISU IBIOIUTIOX I BETBinCI
1 1
1 1
29 » or - 9. S *g/g I a) Bales I Tvkava. a.
•et «t) | 1) resales | Saznki-TMasoto, S.
36 • or - a.o ng/j | l laaao, x.
(vet vt) | HOB a groan of <1 sntopsies. < Teral. 1.
1 forensic sedical exanlnatiani, Japan. 1 1980
t Isles, senn age »0. 6 yr- 'analog, | archives of
1 nean age 37. « yr. ( Zsvironsental Bealtli
1 1 35ID-.3S-M
1 TBICB nzBtns; iirroMiEs: Jipti; 1
1 iiiBnm: usnic: CIDBHTB; coBut: i
1 cncBxra; conzt: IBOB; HIBCDBI: i
l lining! aiGitsivs; aiieiBtsz; i
l PVBIBIDI: ixnaofT; actBDira; i
i snnina: tiuBiot; nnoitnj zixcs i
l con; BiOBiBZ: irrra; noxtTS; i
1 cmmm: CIXIBZIUIB: BUM; ansais; i
1 IIICBBISI SP1IKB: LOISS; iOITl; |
1 a tins: coBpiBinn XTUVMICIS; stt; \
1 1C1ZBSIC BIC1CIII |
1 1
a) 37.2 ng/g Mt vt la) lorker I HyoSo, x.
b) Bot given I b) Controls ( Saioki, s.
1 1 rnrnya, B.
1 JicauM vorkec. 61 vr olo, at 1 Besai*«ka, X.
1 caroaate [rodacing plant for 30 yr. I 19BO
1 tied of nezillarr and lung cancer. I International Urcaives
) Centrals, 59-78 vr old. I of Occupational and
1 1 Znviroueatal Health
1 jirjn- IBTJOSI tissai; IOITI-. mm i ««:i»i-iso
< BlltOf; BBtll: CnEBtllDB; CZBIBBOB; I
1 KIlBEtS; IITFJ: LOBSSj BBSC1ZS; I
I IIBCllU; SXIBi CBKOItBB: COPPXB; I
1 Bints-, tixc: icggstiiii. nms; i
1 IIBIlinOB: CCCOV1TIOBU UZ1IDS; \
1 POPOUTIOI BIPOSB1E t
1 |
1 |
a) 22.2 ng/g Mt vt | i) larter | Byodo, X.
b) lot given | t) Controls \ Suzuki, S.
t 1 Parori, X.
1 Jatanase «otker, S5 yr old. at 1 Resfciiakn, X.
1 catenate cretacing plant for 30 vr. 1 19(0
1 tied of aaiillarr and lug cancer. I Ivtenational Uehives
1 Centrals, 59-78 yr old. 1 of Occapational and
t 1 ZBVlronnental Bealtli
1 »I*Bi IBIMSI tlSSBZ; »OBT»J 10(3 I »6:1«t-15(l
1 BlltOT; BI1IB; CnCBZLlOB: CnXBSDB: I
1 KIDIBTS; Ufa: HISS; BOSCIZS: I
I mcit is; SIM; craonsa: cotpii; i
l nnus: me; n&nsTBtti nins; i
l iiauutait cocnrmoxiL utiios; \
1 ECPDimO* XXPOSOI9 |
1 1
a) 10.1 sg/g Mt «t e ,} lorker I Brado, X.
M B»t given | b) Controls ( snvki, s.
1 1 mrayt. 1.
1 Jatanese worker. CS vr old, at I Beshiznka, X.
1 tfttonat* rrodnclxg plant for 30 yr. I 1980
1 I ltd of sutllaET »& l«ag cancer. t International archives
1 Centrals, 10-71 yr old. 1 of occupational ua
1 1 Znvlronsental Health
1 31t»; 1DIPOSI TISSUE; IOBT1; BOIZ 1 »«:1<1-1SO
1 BlltOt; BStll; CtBZlZLIN: CnZESDB; I
1 xiEins: n»n; inxes; ivscus; \
t (IKBZlS: SIM: CB10BTOB; COPPIl; I
t atTtis: sue: IWDOSIBIIL puns; i
( IiaillllCB; QCCDPKTOBU. BIIlltDS; t
1 fcpouTion txposomz i
                                                                                                                                                                                      SO

-------
Tlie
ta
Itl «5.38, H» (19.5 C, B* 908 c, « 1 aa Bg at 4«7 c. 10 en Bg at 5*0
tissus BXfosBi: TOUTS IIU.TIICU.
BZT10D


•COS I-ra- apeetroe
Spinal
cord









1
1 1
1 1
t 1 l
t 1
««o« I n
Spleen f
(



f
f
t 1
1
1







1
1
1 ««07 IIS
(OllZt | »iei 1 nil | 6BI1UL mCIMHOI 1 BZmBBCZ
or cisKS lit i
1 1 1 1
) 1 1 1
a) 7 |a) 39.6-202.5 og/g I a) 83.8 * or - it. 3 | a) Solar nenron disease patienta 1 Karlander. B.B.
b) 12 I b) 3».6-85.9 ag/g 1 ug/g I t) coatrala 1 Sattan. B.I.
1 BIJ *t 1 b) 52.2 * or - l«.3 | Tvatral kora tis-ae. aatopsi 1 1979
1 1 og/g I 1 annals of leitologr
I | arr vt | fatieata died of avotrepklc lateral 1 *(1)t31-24
1 1 1 fclerosts aad progressive aasealar 1
1 1 1 atropkr. aean age, 5«. 6 « or - 13. 1 1
1 1 1 It. Control! died of varioas 1
1 1 1 diseases at 60.9 « or - 11.1 vr. 1
1*1 1
1 l i TIII-; iBoiiss lororsiss; i
1 i t M-KOTseoiai vz-Bi-xs) srnu. coio-. i
1 i i tioicciTioniiof : CJUCIOB: COPFBBI i
1 l l itoi: itic: ureaixsz; anus; i
1 1 l SniBCTI: ZlfC |
i i i t
III l
a) 9 | a) C.S-45  120 I Salsiaen, B.
1 1 1 41 50 | d) 122*282 og/9 1 d) '85 * or - 10.8 | a-/g ta IB acil 1 1981
1 1 1 e) 26 | e) 143-339 ag/g 1 ag/g [ c) Bentine, arbaa area I Ircblves of Oral
1 1 ( f) 26 | f) 169-538 ag/g | e) 1*9 » or - 20.4 | d) tMael. aa in (a) 1 Blologr 2t:1-6
II II «g/g
1 1 1 If) 301 « or - 42.8
II II ag/g
1 1 1
III 1
III 1
III 1
1 1 1
i f i
i i
i f
i

4C08 Xftgeatian US a) 15 a) lot girca
Triae b) 17 b) lot given
O 19 c) lot girea
d) 15 d) tot givea












t
l -










a) 539 » or - 355
ug/2* br
b| 522 » or - 288
•9/24 kr
c| 343 » or - 222
-g/24 kr
4) 127 * or - 251
ug/24 kr










e) Inaael, aa la (b) I
i) laanel, aa in (e) I
latiaated free grapb (a,b,c) |
lg< depeadeat data al» presented. 1
la accacalated la dentine np to age 1
if 1
1
lesideats of Finland 1
1
niltni 10!; SEX; T.KTB; COBP1BHITE 1
ITlIOlTIOirS: BIOMSW1; Tile; SDMI I
JSI1S; K1B» 1BZ15; BBT1IS 1
1
a) Me. lov (load preeeore 1 aer.ea-ie, J.B.
t) Ma, klgh feloed pre-nre I eathrie, I.I.
c) lonea* lov blood presaare 1 Prior, 7.JI.S.
4) voaea, kigh blood presaara 1 1978
Subjects selected by Uood ptessore 1 taerican Journal of
rank fcon previoas stndr. Bstinated I Clinical ntrition
dailr iietari intake 4.5 ng. I 31:422-428
1
folvaeslan residents of Tokelaa t
Islands, cro«del eoaditions, 1
subsistence econonr. Ben, n«an age 1
1! Tr, aean lit 147 en, ne*n vt 74 kg. 1
leaen, aeas age at vr, nean kt 165 1
ca, aeaa vt 79 kg. 1
1
CCEflE; IT«C: BIOOO SIBOS; I1IB: 1
tins; Mill; 1Z1 ZEU1E0 I
1
                                                                                                                                                                                   N5
                                                                                                                                                                                   O

-------
Stic, Kltr<»?«a 3,7, 12, 17-t«tra»athyl-8, T3-Uiiadiproplo«ata<2-||- (8 CT)
*l»c. n.12-ai»tlienTl-J.8.13,17-t«tr»»«thyl-21S.23H-porphiBe-2,H-dipropiiioato(2-)-I(2I).«W2),I(23|,»(2«»)-.
C3«-H30-M-0«-In- 21
II 626.03
TISSUI

»609
Iloot.
call*













Eiiosvn IOOTE
















>B»1IIIC»1
BETVOD















WSBHI
OF MSB
2«0














iMGS

a) lot gl»a»
b) lot gtT 3V 33 vk aftai caaoral
trrthcoeTtas
(atlaatad frea araph
Cavaldarabla dlt£«t«moa la rata of
ebaiga aaa plataaa stata for Xa
Iaa4 saaltai torkars
ItntlS; BIOOD; MTTHBOCTTIS;
CC9F1B1TITE tTHOlTIOIS; USOSTtlll
iicinit mi: xnc OIGHIC
ccnposins: iieosmsti itiasraEits;
IIBIUTIOI; CCCBPlTHWil BiJWDS;
SRIITZIS
SSfEBXICE

Baslay, E.I.
llabisk, S.B.
1991
Journal of fba taerican
Inanstrlal Byqiena
l*sociation »2:«2-«6










 rlcconlgi
 7»»0-67-7
 It
 Id 91.22. IIP 1852 C. BP 35T7 C
TISSDC

Bale
















IIPOSOBE son:

















t
lutmcit
BETBOD

















IOBBSB |
or CISES

















11I6E 1


















1Et(


















fillllll I«roBB»TIO«

Vavia»« 2V caprasaata,tiTa
pra-a*alT»la tr«ataants ara
tatnlataa. Iba faacibllity of a
bcllatle. no-«a»h policy for hale
laalysls 1* outliaaa «ad supported.
f If III; TB1CI I1HEITS: Bill;
IDSTBllH; >IlSOIZR»t IZIBODS;
»11LS; PBOTHIS: COMIUTITI
IViLV&lIOVS; 1L0BIVQIC; 1I1TBOIT;
»siuc: Slim; BKonil: CICFIIDS:
ciicnn; CKOBIIZ: CBBOIIOB: coiui:
CCPPEB; Sllliai; GE1H1IIOH; £010;
login; iBon; tiRBma: nit;
MGIEStVl; BlIGUKI; BIBCUBI;
tatmimn; HCKBL; CBOSPBCBOS;
fQlaSSIHH; SDBIDIUB; SEIEVIQB:
siiicoi; suns; SODIIB; SIBCSTMH-.
soiroB; in; Tinnm; tuiesni:
II1C; ZI1CCII1IB
BEFEIEICE

Chittlaboroogh, G.
Sctaac* of the Total
tITlXO*MItt 1*5 53-75














                                                                                                                                                                                           N)

-------
     1-eataaol. J-**»rt-
     C«-B1«-0
     II 102.17. If -tS C, SI 1»8.9 C.  TP 9.9 •• tl it »  C
tissue

»S11
Bre«t»












EIKISVB BOBR















IBIIITICIL
HCTBO9

8C-HS













BOMS*
or cisss

5* (387
saaples)












11(61

Vat 9lTea













8MB 1 C1BZB11 IVFOIUTIOI
1
1
t
1.12 B«/l ( Beanred at 25 C aad 760 II Bo
Ceoaetric | »S.S* ooearmee
1 ze»«r aa& apper osw-sigaa Jiaita
1 C.370 aad 3.3» aoyl

I BMlthr. i*-3S rr old. B«an>)ri«9,
1 «rtia black* »»4 caocasia ni.
1 cficaqo, 11. BtqWlT co«troll«l
1 «ip«rlmttl co«ditia».
1 III1TB; IICOEOIS; II1IIOIS; tDHUS;
1 ciiatinrtt mtocntoiss TOIJTHI
l ciemc coircojDS: mm HUIBDS;
i IHIUTIOI; mimisa; uiiaoims;
1 FCFBiirro* nposni; JBBI» IBIIS
tETEIIICI

Kcota«ia i »
                                  at ixs c
Tissm
««12
Breath




1
1



I
1
1
1
1
1 siresms aonz
1
1
,'








1
1
l
1
l
1
i
iBunicii
HXTBOD
OC-9S















•0SBSB
or cisss
W (387
saaples)








1
*

1
1
1
1 BiBei
Bot give*











1
1
1
1
ms»»
12.3 ag/1
Geoaetrie














6BBIBU IlrOtUTIOB
Caaanred at 25 c aad 760 aa Bg
?.»* oecarrenc«
lower aid afpec one-stga« Halts 3.*3
11 <5 *1.8 aq/1

Bealtkr, 18-35 ji old, nonsaokin-g.
Qttaa blacks aad caaeaatana.
Ckicafa, II. Blaldlr conttoUed
•xpcriveatal coaditlons*

HUTt; IICCBOLS; IILIIOIS; IDI1TS;
CBLOBIMItg JIBSOCJBBOIS; TO II TIL!
CIGIHC COStCJKDS; BE1ITH BIZHftS;
IIB11ITIOI; BtTtBOLISS; BB11BOLITZS:
KJTOUTIOI taosnsi UIBJI 11:15

UrBBKBCE
Krotosxiulci, B.K.
Brnaeaa, Q. B.
O'Seill, g.j.
1»79
Journal of Inalitical
loitcoloqr 3:225-23*










                                                                                                                                                                                           to
                                                                                                                                                                                           10
                                                                                                                                                                                           ro
 1>Bat«a*
 10»-»8-»
C«-»8
B* 5«. 12,  IP -185.35 C, BP -6.3 C,  »P 3*80 aa B« at 21 C
I 1ISS»
1
1
•613
Breath










tirosvtt tons












1 IBlimOL
I ireraoo
OC/HS











BUBBH
OF C1SES
8











81HSJ
Bot detectcd-510.0 og/hr











RE1I
78.8 ng/hr











GM1S11 HfOHlTIOI
Ccapond relates to iroraal
tetabolisi. Ho other detaili giTen
Cirogeaic sampling teckalgne.

I«altbT lilltair and clvillail
eiployeea, o.s. ilr Force school of
Mtospac* 9«dlciM, aqea 23-*7 ji. 3
stokers.
tllZMXS; CaiOBIBaTlD HTDBOCHEBOIS :
CElOBtH! OBGltTC COBTODIBS;
cEioioBHiiiiis: naoaiK cosiovins;
IS! KB: ILCOtOLS: THUS; AUDITS
KFIBZBCI
Coakle, J.F.
Caap, B.J.
Reich, B.E.
1975
archives of
EnTiroeaeotal Health
30 mt 290-295






-------
I07-00-S
C«-B6
If 5», HP -130 C, BP 8.J C.  TP 100 M Hg it -«.* C
TISSBS
«1»
Breatt










8IPOSBSB Bom












tlltTTICJL
BET HOD
.
ec/ss











IHIBIR
or cisis
s











MIS:
lot detect«d-3.* ng/hr











1E1I
0.« ng/br











critiit nroiiuioi
coapomd froa ukaon orlgla. la
ctfctc to tails given
Crroq«iic KipllD? technique.

KalthT illttarT ail elrillai
•?ploTB«5, g.s. lie farce School of
leroapac* n«dici»», ag«s 23-47 jt. 3
tiokccs.
ItlZElIS; CBIOTI1»TZD 8TDBOC1SBOIS ;
CE10BHB OIG1HIC COHPOnOS;
C8IOBOBHIIJIS: nOOIIK COSPOB1DS;
EI1IIB: 11COEOLS; THIS; 1D01TS
SZ/E1EICB
Conkle, J.p.
Caapr B.J*
Belch, B.t.
1975
IrchiTes of
EBTicountal Besltk
30<2>s290-2W





1-lexuetbiol
111-31-1
B«  119.2*, HP -B1 C, B? 151 C
TISSBB
•«15
Breath












EIMSTJES MUTE













iiiimcii
nilflOD
ec-Bs












•BBBSt
or cisss
5« (387
ncpLes)












B1BGB
lot given












Kill |
1
2.2 ng/1
seoaetrie











1
email nroaauioB
B«aaaced at 25 C ami 760 >a Bg
15. a* occamace
Lc»«T and apper aa«-sigaa Halts 1.0
•id *.« *q/l

BcaltkT, IB- 35 it old, aonsaolcliKi,
gctaa blac\s tad cavcaaiaas.
Cblcaqo, 11. Blgldlr coatiolled
•ipcrlaeatal coadltloas.
tlBlTB; tlCCBOLS; ItUIOIS; ID01TS;
tFLCSIlHID ITDBOClBBOBS; TO11TH.I
CSSIIIC COBPCOTDS; BI11TK BaZttDS:
1IB1UTICI; UTIEOIISB; BII1EO1IMS:
IC?m.»TI01 IIPOSOSE; BBB1B IBI1S
similes
Kcotosilnskl, B.K.
Bcaneaa, G.a.
O'Beill, B.J.
1579
Joacaal ot knaljtical
Toilcologj 3:225-23*








                                                                                                                                                                                           N3
                                                                                                                                                                                           U)
  10»-7«-7
  «-S1l-0
  BB 130.22. B! 18*-1(S C
1ISSUB
16 1«
Br«ath












KIPOSOK FOOT!













ivaimcu.
BBinOD
SC-BS












10BB55 |
OT CISIS
5» |387
aaapteO












BUCK
*ot  Bq
17.6* occurr«nc«
Lo««r aad upper oae-slgaa Halts 1.3S
aid 11.9 iig/1

B«alt«T, 18-35 TC old, aonsaokinq.
ntlao blacks aid eaaeailaai.
Chicago, II. Ugldlr conttolled
iipaclxntal coadltloms.
EBfHB: ItCCBOlS; IlLIJOIS: JDItTS:
CBlOIinttD BTDBOCilBCUS: (OUTH!
cieinc coBTcmiis: BB*I.TH HIT»BDS;
IIB4I1TICI; KRItOlIS!!: aZIUOUTZS:
tOPOHTIOB BUOSOBB; 1BB1I IHaS
tmiEBci
rrotosznskl, B.K.
Brnneao, G.a.
O'»«lll, B.J.
1979
Journal of Inalrtlcal
Toilcologi 3:225-23*









-------
     1-0ct«w. 2-Mtkyl-
    t»-B18
    n 12S.27
tlSSTJB

•617
3raatk












smsoBS Bonn















imiricii.
BITBOD

OC-«S













itmm
or CISTS

54 (317
saaplcsl












BIIGI

•Ot ppw OM-S19M lilitl 0.83
lid 5.3 *q/l

!««ltbi, 18*35 Tr old, nonnakint.
ait« blicki *nd e*ae»i*n<.
Cbiciqo, 11. Btijldlr controll«a

-------
1-Peataaol, 2,2,a-trUflthTl-
1S3-O-*
C8-B18-0
II 130
TISSUE
»620
Breath








"




IIPOSOBS BOVTI














IHLTIICit
mama
GC-HS













IOSBEB
or CUES
5» (387
saaples)













XilSE
lot givea













ftKll
1.2 nj/1
Seoaetric













GEIHaL XnOSRaTIOl
ecasored at K c ana 760 •> Eg
»7.«1 occurrence
lover and offer one-Si gia liaitc 2.2
aid 7.9 »q/l

Bealtty, It- IS yr oil, Boaiaokiaq.
atlM blacks and eatcasiaas.
Chicago. 11. BiaLdlr ontrolled
ciptci natal coodltina.
E8IHI: 11CCBOLS; IlLIIOIS; IDH1IS;
CaiOIIltTZD BIOBOClBBOtS: TOUTILE
CISXIC CC9ECOIDS: ailllH mZHDS;
HBlUTIOl; BETIBOLIS9: HIT1EOLITES;
1 fcsonttoi inosoai; IEBH u»s
1 	 ; 	
EtnmcE
Krotoszjasklf B.K.
Brwean, 6.1.
O'Mill. a.J.
1979
Jotirnal ot analytical
Toilcologi 3:225-23*









 1-P»ntene
 109-67-1
 C5-H10
 »» 70.13, 8P r12» C,  BP 30.1 C,  TP  «00 •• Hg at  12.S C
TISSUE
11621
Breath










tMOSWE SOME












antmcai.
BFTHOD
GC/HS











IOHBSB
OF C13SS
8











sues
lot detected-ISO. 0 ng/hr











an*
3».1 ag/hr











sEtraiz. i«rosaiTica i
Coapoud related to aonal !
MtaboUsi. (o other details 
                                                                                                                                                                                           to
  1-Propanol, 2,2-dttethyl-,  acetate
  926-»1-0
     130.18
tissn«
««22
Breath












! IPOS US? BOOTI













JlULITIClL
maoo
ec-«»s












IDHBa
or cisis
54 (3B7
saiples)












BHSI
Vot glien












H21I |
t.» ng/a
•Jeoaetric












CtHEll HT01B1I1CJ
ecanrel at 25 C »nJ 7«0 mi sq
38.8V occurrence
Lcner aal apper one-Siqaa liiits 0.86
and *.l na/1

IKalthr, 18-25 rr old, nonsiokiiig.
irtaa blacks an 4 cancaslaiia.
Chlcaqo. Tl. BigidlT controllea
ezperiaeBtal coaditiofta.
IBI1TB; HCCBOIS; IllIIOIS; 10DLTS:
CElCBimTIO IHIEOClBBa»5; T011TIL5
cisinc coBPcnos: BIIITH HIUJDS;
UBitiTici; BZTaroLisa: BEIIKII.IIES;
fCFUtlTIOK IIPOSISE; IBBal IBEIS
KtttZtCt
Krotosrinsfci. 9.K.
Brtraeaa, a. a.
C'leill, B.J.
1979
Joaroal ol analytical
ToilcologT 3:225-234









-------
 1,3-tropaBVdlol.
 ST-S3-*
 C9-SW-l2-Oa
 «t 2t«.2S. at 10«-106 C
nssvt
•623
plant



ntromc ions
laoaatioi




iiumcu.
RSTBOD
ec




mrnSI
or cuss
i




iue>
12.S-7 ag/al




nil
lot applicable




CEIHII nrosiuici
1 aa< « lr aft*r SOD a« i> aolntioa.
Xaitial nlaa, 12 «-crclob*ta(cd>)p«BtalM«, 1,1a,2,2.3,3«,«,5.5.5a,Sb.«-4od«c«cWorct«kraro-
33*5-8S-S
C10-C112
SI ««!.«, IP (85 C,  TP CIIO(I-C)  u ng at SO C
1 iissnt i sxrosmt totrti i intmciL
1 1 | IRBOO
i i
1 i
•(» i ec
aAipom I
1
1
1
f 1
1 I
f I
I
1
1
1
1
1
1
t
1
1
1 1
»0»!SS IHGI 1 BK1I 1 CEIIUt IlfOIBlTIOl
or cisss i |
i i
1 |
M» •) lot 9i»« 1 a| 0.172 » or - 0.937 | •> !«•• 9-1* yt
b) lot ji»«» i pp» | tj >?» 15-M rr
c| lot jir«o | b) 0.2«3 * or - 0.039 I e) !«•* «5 Tt or >
4) lot «ira | ppa ) ') Ust Sottt caatral ceatts
I •) lot glim | e| 0.297 » or - 0.077 | •) Sotta Itlaatie cams
1 f) lot aim | ppa ( It Mat Sovtb Caatral cersos
I g) lot glna I d) 0.292 t or - o.oig | q| caacadaaa
h) lot gtT«n | ppa I b) loa-ca«cab •) T - IlpiJ axtractatla
1 ppa | lataclal a41«tad. Ml«ate4 iata
1 fl 0.252 » or - 0.03D | taaaft on alta« Spwlal Study, ri 7«.
1 »Pa | liaitations cf aaaplc Mlactlon
1 h) O.«06 » or - 0.102 | ntaotolaw r»atrict iitarpntatton
1 opa | cC cvaalts.
f 1) 0.322 * or - 0.085
1 PPa Simlcal patlut* aid eatarata in all
1 1) 0.2«9 • or - 0.023 eoaatlai >itt «ir«r as* aarloo 10 TCI
II II I PP» u, re. ai. n, «s, ic, sc, 71.
II II 1 S.I.
II t 1 1 OeoMtrlc ««i* lUBJtll; n.01191; GK3BSH; lonisiila:
1 ' II 1 HSSISSirPX; K>»TB C18O.III: SOOTH
1 1 1
1 1 1
1
1
t
1 »625
I tloot.
I »bol»
1


















t
1
1 1
i SC-BC
l
1



















I
















») 3S
b) 12

















1
1
i
i
I CICOtlll; THIS; UIKSt II5S02:
I IHSICTICIDBS; Eioicccrsouuoi: rooa
1 CCITMII1TIOI: PBSTICIDBS
	 1
1
a) lot 4et*ct*d
b) lot 4at«cted





















a) lot d«t«ot«d
b) lot dctvcteil




















-


a) toTa Caaal r«aiA«ata
r) Tolaateaxi
Halt of a«*tar«a«Bt, 0.22 to/v
Cloaalr aatci*3, iia«lt«a«oia control
taatlas oera aot prortieiJ for
• minis alcaq alta those ttoa tt« 36
lera cual ares rcsiiaats a»apl<4.
lactlif eeaaiaqfal control or
litcrttare data r«litin to ti»
sl?aiflcanca of ta« lo« raaldvaa
tctti la ta« field «aple» aialmd.
no 4efiiit* coaclaaloas caa ba oravii
froa tk« tssolts c«ported.
Kaidvats of lav Tork. Controls,
aifloToas of ta* SBTiroiMatal
Trotectloi IOABCT aid mltorsiti
stoieata, lorth Caroliaa.
Ill TOBK-. ICRfl C»OU»; B1009;
BHSOEMI1T IITBOOS! CBWBIII OJGIIIC
CCHOOnS: CBIOJOBIIIIISS;
iiiiciLoicBinns: poLTcatosinTro
IIIHItLS; TWVL1TIOI IIKPSUBE

S»EIE*CI

taiaiaqer. C.
•atta, D.
sptraeiDO, C.
Illliau, S.
i»sa
IPS 54«/!3-«O-02«, (08
pp.





















rlatol, 0.1.
180
P1-600/1-80-OJ6, «0
P.



















                                                                                                                                                                                         u>
                                                                                                                                                                                         N>

-------
1.3,«-Betheno-2H-CTClobuta(cd|pentalan-2-one,
H3-SO-0
C10-C110-0
II MO.68. TP OI10CB-71 •• 84 at 25 C
                                                ,1a.3,3a, «,5. 5,5«,5»,C-o:ec«cUorooctaaydro-
TISSUE
*626
Blood,
•kola


























KXFOSmi BOOTI





























ininicu
BKTHOD
9C




























IOBBJS
OF CASES
tea




























UI6I
») .009-11.1 ppn
b) .003-*. 1 ppl
e) .003-0.39 ppa
d) .003-0.45 ppn
•) .003-0.031 ppa
f) -OOS-O.OH ppn
g) .003-0.00* ppn
h) 0.005-0.0325 ppe





















mi
») 2.53 ppn
b) 4.60 ppn
e) 0. 10 pp«
4) 0.06 ppi
e) 0.011 pp*
f) 0.008 pp»
9) 0.0035 ppi
h) 0.011 pp»





















6KIIHL IIFOIR1TIOI
«) ST ill •i;loT of Lif« Scl«aca
Prodocts Co
b) »8 nuffacted aiploy***
c) 30 £«iilT MBimrs of aiployets
d) 30 employes of llllvd Che*ical
Ccrpor*tioB pnvioislT In Icpona
CIO duct ion
«) 23 aiplofMs of uearbT b*sin«ases
() t saraq* tnataent plant enployees
q) 2 cab OT truck drlnrs
k) «0 residents within 1.6 1» of Life
Science frodocts Co
Besldants of Hop«well, Ti
Significant difference In frequency
of irnptoaa In kepome vockecs aa
ccnpared to area residents: Bashf
•ervananess, teesor, Tlsnal
difficulties (p<0.001), plvuttic
tain and velqnt loss, (p
-------
1.*:;,8-DlsetkaBmapktb.aleae, 1,2.3.*,10.10-kaxacttoro-f.«>*a.5,*,*a-kex*kydro-. eaido.exo- (8 CI)
1.*:$.8-DiaetkMoaapktkalene. t,2.$.*.10,10-kexaCaloro-1,*.*a.S,8,ea-bexabriro-. (1alpaa,talpka.4abeta.5alpka,8alpaa.tab*ta)-
3C9-00-2
                                                                                                                                 CI)
B» 3«5.tl, RP 10* C, TP «I10(E-«)  an Bg «t 25 C


























«ISSITB



IC28
iMlottc
fluid










*«29
Blood















«*3o
ni tt







i
«
I

I


•631
Placenta











»6S2
Placenta














EIPOSTOZ son

































IftOestioa






aitiTTicai. i IVBBS> i tun
SEtHOD J or CtSSS I
1 1
1 I
9C-K ( 50 1 1-152 ppb
1 1
1 1
1 1
1 1
1 1
1 1
1 1
1 1

1 1
1 1
1 I
OC-IC 1 t) 25 I 4) lot 4et«ctable-23 ppb
I b) IS | C) 9-80 ppt
1 C) 10 |e) 18-70 ppb
1 1
1 1
1 1
I 1
1 1
1 1
1 1
1 1
1 1
1 1

( 1
1 1
1 1
oc 1 a) 21 | a) tot detected
I b) 2« f b) 0-0.0*0 pp«
1 c| «5 1 CI 0-0.0*0 ppa
I t) «5 I 1) lot given
1 1
1 1
1 1
t 1
1 1
1 1
1 1
1 1
1 1
( 1
1 1 1
1 1 1
1 OC-BC | 50 I 2-1587 ppb
1 1 1











C















1 1
I (
/ I
1 1

1 1
1 1
1 1
1 1

I |
1C- EC | a) 2S | a] lot detectable- 15 ppb
1 b) IS | k) lot Jot ectabl e-110 ppb
1 e| 10 | e) lot detectaUe-2* ppb
I |
1 1

1 1
1 1
1 1
1 1
1 1
1 1
1 t
1 1
Bill 1 GEIZIlt XimMIIO* 1 IWMEICE
1 1
1 . . _ 1
1 I
20.76 ppb 1 18 posit IT* speclnas 1 Sarena, I.e.
Geoaetcie 1 | Sett, T.P.
1 Pregnant reeea. similar in I Bahajaa, f.L.
1 sccioecoaoaic level aad dietar? | 1980
1 babits. 10 oceapatioaal or i Intinational Joanal
1 accidental exposare* lacknov, Xodia f of Znvironatttal
1 1 analytical clieilstrr
1 FIST 1C ID IS; CatOHItnO BTCSOC1BBOIS; | 7:2*5-751
1 CBICSIJ! OBSJHC COJIPOOIBS; EDI; 3DI; 1
1 IDT; IIDI1; EBESIUCI: IBIIOtlC 1
1 J1DID: PHCIIT1 1
1 1
i r
a) 11.1 * or - 7.3 I •) Co*trolit fall-ten pre;ia«cle< I Sanaa, I.e.
ppb I t) Pre-teri fr»Ua. I 1*81
1 1 Journal of analytical
1 !•«»: IBOBlioi: 1DOLTS; rnos; I ToxicologT 5:<-*
I noci: Piactni: COBPIBITHF i
I tmamois: cuotruTta i
| ItrBOCaSSCIS; CB10XII! OROHIC 1
I COCCOIDS; I1SECTICIDIS; PISIICIDES; 1
I rtsnciDi stsiooBS; popuiiiici i
I jitosoBS: piteiiicr «
1 1
1 1
a) lot detected I a) Siral icthers, fat basia 1 Pozo lota. t.
b) 0.00* pp> | r) grbaa setters, fat basil 1 Becrera Barteache. 1.
c) 0.003 ppa 1 e) 111 aetheia, fat basis I Polo rillac. L.B.
d) 0.0000* ppa | d) 111 aothets, saol« silt basis I loper-Cieenez, 8.
1 Oata for mi of all pesticides aid 1 Jodral Tillarejo, B.
1 ceiparisns sltb rallies of otker 1 Iglesias Perez, J.
1 lavestlgatore aiven \ 1979
1 1 Bevista Espanola d«
1 »n rains aothcrs free Cordoba region, t Pediatrla
1 3Fai> 1 J5(20S):»3-11«
1 1
1 sftj»: tmiTS: si«: CBLOBHI oieinc i
I coipooioj; ptsTicnts; IGBICOIIOBE; i
1 ID11L lltIS; DRBlf USaS I
1 1
1 1
158. 7 ppb 1 «« poiitiY* ipeciie«« 1 Saxena, B.C.
se«etrle I I Setk, T.B.
1 Ere«naat vonan, aiailar in I Bahalan, P. t.
1 locioecoionlc lerel and dietary 1 1*80
1 babits* lo cecapational oc I Tateraatienal Journal
1 accidestal «rposare. luctmo*. InSla 1 of Cnvicouaatal
1 1 analytical Chealstrr
1 CISTXCIDIS: CBLOBIlim BTDWCUBOIS; I 7:2*5-251
I CBIOBUE 0161IIC COBPOH1DS: toE; DDE: I
I ItT. IIDI1: PKB6IIKT; IBIIOIIC 1
1 line; pLjcim i
' 1
1 1
»1 » or - 3.96 ppb | a) control!, fall-tern pregnancies 1 Sanaa, B.C.
17.9 « or - 2«. 1 1 t) Pre-tern tregnanciajs 1 Siddiqai, B.lt.J.
>b I cj spontaneoas abortions at l*s* tbaa I Setk, T.D*
IS. 9 • oc - 7.6 |8 «k (incudes fetas) I Xrisbna Bnrti, C.I.
pb t 1 Bkargaia, a.K.
1 Bealthy, non-exponel, pre^iant aonen. I Rntty. D.
1 age* 18-32 yr, ladla. I 1981
1 1 Journal of analytical
1 lIDIa; aBOITIOl: 1DOLIS; moS: 1 Toxicology 5:6-9
1 nocoi pxtCEnt: coiPiunn I
1 fTllVaTIOIS; CBLOIHUZI 1
1 IHBOCUBOIS; CHIOEIK OXGI1IC \
I cciiomis: iiSECticnis; PESTICIDES-, \
\ tISTICIDt BlSraVBS: VOIBLatlOl 1
11 t 1 IMOSUMt fltetlKT (
1 1 1 __..... 1 1


































OJ
M
oo











































-------
1,«:S,8-Dinetbanonapktkal*M, 1,2,3,a,10. 10-nerackloro-«,7-«pOT7-1,»,»a.5,6.7,8,8a-octanT4ro-. «uoo,«xo-  (SCI)
2.7:3.«-Din«thanoaa?hth(2.3-b)oxir«lie, 3,«,5,6.»,»-b.«iacliloro-1a,2,2a.3,«.«a,7,7a-octabTtro-, (1«alpha,2b«ta,2aalpha.3b«ta.Sb«ta.6aalpha,7bet»,7«alph«)-  (9 CI)
60-57-1
I* 380.93. BP 176-177 C, TP 7.78X10(1-7)  » 89 at 20 C
TISSUE



•633
Idlpose
























*63*
adipose










•«J5
Iniotlc
fluid








rosns SOOTS




















































lULTTICaL
BET HOD




























GC











SC-EC










RUBBER
or CISES




























60











SO










UEGE





























<0. 05- 1.16 ppa











1-3 ppb










Bill | GEIllaL IlfOSHlTIOB
|
1
1

J
1 Exposed persons in the United States,
1 the «ether lands, Sweden, Israel,
1 Japan, OSSB, Poland, Geruany, India,
1 Evlaarin, Pakistan, Austria.
1
1 Beported cases of hypertension.
1 elevated serin ckolesterol. abnornal
1 lies, or iipairnent of neareauscular
1 function after acute exposure to
1 conbinations of pesticides, bat nost
1 datn show no aSnrs* effects after
1 Icnq-tern occupational exposure.
| IDSTBIa? BOXGlBIl: GBRRaEY: X1DI1;
| mm: JlPtl: IETB1JLMDS; PaKISTW;
I ICLMD: 1DSSI1: SVE9EI; BIITED
I SHIES: tDIPCSE IISSOE; B1OOD: BLOOD
| tUSHa; BIOCO SEME; EITTBEOCTT1S-.
| ItmoCTTES; BI1K; DBIBE; K1TIEB;
I BIILTH HIClBtS; OCCOPlTIOlll R1X1BDS;
I topniTio* EXPOSORE : IEOPIISRS:
1 CISnCIDIS; CEXOBIIE OBGallC
1 ccRponas
1
t
0.26 ppu I Peripheral kidney fat, routine
1 cntholoaical exaninations
1
1 Iges 6 no-92 yr. Belgian
1
I t»sim: iDTopsiES: IDIPOSS nssas:
1 EIOlCCqilUlITIOI; PESTICIDES; DDD:
1 ICE; DOT; DIILDKII: BBPTICHLOB
1 ItOSIDE; RSXaCnOBOEEEtSlE: URDUS;
1 CrtCIIRS OR61RIC CORP001DS
1
1
2.«2 ppb | 2 cositi*e specinens
Seonetric I
1 Vreqaant voaea, sinilar in
1 tccioecononie leiel and dietary
1 tab its. 10 occupational or
1 accidental exposure. Locknoi, India
I
1 EISTICIDtS; CHLOtnUTID BTDBOC1SBOIS;
1 CCIOSIIS OSGI1TC CORP01KDS; EDO; DDE;
1 CCT; n»It: PtESRllCt; 1B«IO«C
1 IIOID; PlaCtrta
lEfEHERCE



Deichnann, f.B.
RacDoaald, I.E.
1977
Ecotoxlooloay anfl
EnTironnental Safety
1:69-110




















De^onckheere, V.
Steurbaat. I.
Tecstraeten, E.
Kips, B.I.
1978
Toxieological European
Besearch 2 (2): 93-98





saxena, H.C.
Seth, T.D.
nahajan, i.L.
1980
International Journal
of EuTlronnental
Inalytlcal Chenistry
7:2«S-2S1



                                                                                                                                                                                           LO
                                                                                                                                                                                           ho
                                                                                        (HIT

-------
1.«:S,«-VlMtkUMtpktk*l«M,  t.2,J,«, 10,«»-a««clil  3,»,5.6,9.^-fc«l.ckloio- ta,2.2»,3,8,6«,1,7.-oet«kTteo-.  ll««lpi«,Jt>«t«.3«alp»»,
«0-!T-1
C12-1I-C1S-O
«t MO, tj. IF 17«-177 C, T* 7.7*««(M> u Of  at 39 C
a, H>«t.,6..1pli«, 7b»t«,7«.lpi4) -
                                   CI|












































1
l_
IISSBI

«3«
Blood









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f
t










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or cuss












































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i RUI
t












































EEftut matnnat

Kile*

trroae4 (wcicta ia tie 9aite4 States
tke letaerlago*. Snjaa, Iiraal,
Jipio, 7SSB. Polaad, saraajf. Itdia,
6«fact«< caa«4 of aYP*ct«aaiGa«
1 elevated eecaa caoleaterol* abadnal
I ties, or lipairaeat of (eareaaaealar
1 faactioa aftec acute aiposuta tp
1 caabtnatioaa af peatlei&ea, tat aost
1 iata aao* ao adverse effect* after
1 lc»«;-tecai occ«p«Uo»al exranre.
I lusTBii; BDtsisii: extdiiT: HOTI;
I ICIUB: SDSEIl; SIlBtl; MltllD
I mns: witcst nsstrsj steccs ttooc
I Hijtocrrss; HIE: aiint: ss7iia:
1 E111I3 HH1EIS; DCCUTiTHUU SUlttDS:
I FCPOHTIO» IlfOSffBE: HOPtJSBJ;
| ftS^ICI»!S; CBIO«»! OtCllTC
( Kt fOaltS: lIOTllSiS; PISI1CIJBS;
I cncem OIGUIC COIPOHBDS
i
1 *«!av
1
1 tipo»4 p«t»ots la tM anitad states.
1 taa Ketherlaada* Svedea* Cacael*
1 Japan. OSS», Poland, Secaanr, India.
Eolijarla, Piklstao. Hatrla.
B.port.i oaes «f ariwcteB.ic*.
!!5s. or iapatraeat of aeireanacajar
(aaetlag alter aeota etooiua ta
ccabittatitfa* of peaticid«av bat a0at
Jata ako» vt aAvetse effect* aftec
leaf-ten occopatioaal «ipo*ura.
icsTBii; aoiemi: GEBUIT; nmi;
ICI.1I!>: S5SJ11; SWHEt; UStllD
miss-, isiecse IISSUB; sj.coc: noofi
ttisnt; iiocc siftw: EiiriEocrns:
itmcocnss: IIIK; «*»i; atrz»:
BIllTJ BIZJBCS: OCCOF11IOUI IIIIKOS:
tcenmoi nnson; nonues:
IISTICI3IS; CBLOBIII OIE1IIC
CCSPOO«3

tzntnci

twlckaaaii, I.B.
KacsoftaUi ?•£•
1977
Ecototlcolo^T aal
rarlruaeatal Safety
1tS9**t 10

















Deichaano, I.B.
McBoaall, >.t.
1977
3c0tdxlcol&9y aa&
eorlraMantaJ Safety
1:89-1*0
















                                                               U)
                                                               OJ
                                                               o

-------
1.atS,«-OlMta.aBOU.pBtsalam«, 1,2,3.4,19, W-JiMacHoTO-«,7-«po»-jr1»*.»a.S,«,7,0,8»-octa«f«ro-,  ««do,ezo- ft cl)
2.7:a,$-DiMta.aaaaapata(2,3-b|oxlxeM. 3,aT5,6,9,*-besacU.9ro-U,2,2a,3,6.6a,7,7a-octahrara-.  
it ii i GEituL tnoiuTia* i (znmcs
1 1
1 1
I IfTiav I Deiciaann, ».B.
1 1 a»cDon»U, H.t.
I Eipos«a persons la tin OniteS states, ) 19T7
1 tl« I*tk«rl»4a, 5r«l«B, leraal, 1 Icotolieolojy and
t I>p*>( OSSB, Falmsi, (S«rnBT> I»ilia. t CnTlcaueital 5af«ty
1 toiler U, T«U«t>«, lartria. I 1:69-110
4 1
I E«port«d cu«a of kypcrteaaion, 1
I 4l«vat«d •«€«• cbol«kt4coj.c ab*4r*ftl t
1 lisa, or liptlrxit of n«oro»aacnl»r I
I (giction aft«c «cnt« •ipo«nre to 1
1 coitiutloia at p«stlcia«9, bat lost 1
1 iitt Stan 10 alT«rs* affects after 1
1 lem-t«n occupational «rposire, f
1 1
I losTRii: BULcuit; eraiui: ni>i>: I
i i si in.: Jm»; innmins; luistti; t
1 101 110 ; 1USSII! SnOH; QllttO \
t STUBS! ID t POS1 TISSOS: BT.OOB-. BLOOD I
1 FUSBl: nOOC StElI; SBTTBBOcnBS; I
1 itnocTiis; mit: mm: tmn; t
1 HUTU R11MBS; OCCOPJTIOIU RlZUItS: 1
I ECPtnitioi uposne i
i i
1 1
O 0.2 ppb « al Rural tiacla I rtoklm* J.
bl 9.2 ppb t t) Qtbaa ll»clts 1 Prtoater. l.i,
c) 0.3 ppb j c) Dcbn c**ca«lau 1 Cceason, J,f.
d) 0.* ppb t i) Kuial ca«eaalanm 1 Ra«Mt, T.
| 1 Kim«*. T.
1 ortam an! total r*ald«ats of sc, 1 laucc, D.t.
1 iifaats, chlKna, .Salts, «M«tlT. t 1972
1 1 li«rica> Journal of
1 SOOTB CKOlIll: AJOITS; CBIIDfiSI: 1 Public Health
1 I1CUI STV91ES: BIOOO PltEBl; 4 6201 = 615-451
1 CCimilTITZ ITllUTIOIS; DOI; PDE; 1
I cti: niBuilii PISTICICJS: i
1 KncHto»rmjo BI?H«IT.S: HI \
\ tCHBTtO»: TOOD COIIUIimoi; 1
1 tisiictot BisiDOES: nmiTion i
I tirosn*: (ITUL UEIS-. tie it istis t
«.) 0.031 p?i 1 *l »nt«l «»tb*r«, rat baelr 1 Foza Lota, R.
b) 0.010 ppa | t) Dtbaa aothats, tat ba«i« 1 Bercara lartaicha. 1.
O 0.020 ppa | c) 111 a«tb«t>, fat basis I Polo Tillar, I.I.
i) 0.0005 ppa 1 SI til aotb«r», (kola silt basis 1 Lopai-Sl»an«i, B.
1 tata lor na of all BMticiBtn aid I Jodcal Tlllar«jo, a.
I ccaparivoaa vltb »»l»s of otter I T<)l«$ias Petal, J.
1 iarcstl^atocs qiraa I 1)79
1 1 (arista Xapanola a«
I lacciaq aotb«ts fcoa CocJoba realm, t Milattia
1 S^aln 1 3S(2l>6l:*J*1tO
1 t
1 stm; utritsj friu: CHLOEIIZ OBSIITC i
l coepcons; ptsncijis; ISBICTLTTIEJ: i
1 tOBIL U!1S; OBB1» UB15 I
1 1
1 1
UI.2 * oc - a.3«.z | coapated on tat a41asteA basis t savaa*, I. P.
ppb | Fauna of a«au for all gaogiaphlc 1 X«efe, 1, i.
I c«qlais I tcsaaci, 3.0.
1 1 laealar, B.«.
1 Kcaln? aotfurs, IT. S.I. 1 Ipplebaaji, ».«.
I 1 Coos, I.*.
1 UIITID STiirs; IOOITS: ans: i rort, 5.1.
1 CCBP»1»IIH ITILVIIIOIS; CBLOBIC | 1941
1 cremc CD8IOOIDS; DISLDBII; | laerlcaa Joarnal of
1 ItSIICIDK; laCTmol I Epl4««lolo«r
1 1 1 W3 1«| i »U-»2J
t 1 1
Oin PIS!)

-------
    t.»:5,8-Di»etliaaoaap«t»alene. 1,2.3,4, 10>10-kexacU.aro-6,7-epoxr-1,B,Ba,S,«>7f8,am-octaavdra-, eodo,exo- fl CI>
    2.7:3.6-!)lMthanaaapktb.(2.3-b10xixeBe, 3,*,5,6,9. 9-hexaCBlora-1a.2,2a.3,C.ea,7,7a-ectaavara-.  (1nalpBa,2beta.2allpha.3beta.Sfceta,6aalpha,7beta.7aalpna)-  (9 CIJ

    C12-B9-C16-0
    !1 380.93, IIP 17«-177 C.  TV 7.7W10B-7} •• Bg at 20 C
                                                                                          (COITC(VED)
• Tisstn


4642
•ilk, tat














4643 |
Placenta I
1
t








IZPOSBIS BOOT!




























aflLTTIClL
RETBUU

OC-BC






'
1
f





SC-EC










nnsa
or cisss
















50










SHOE


a) lot given
b) lot given
c) tot given
d) Hot gives
e) lot given











1-6 ppb










nil i ecimi. XBFOBRtnoi
I
i
a) 0.086 * or - 0.063 I a) 1972, 40 saaples
ppa | b) 1973. 38 saaples
b) 0.99S * or - 0.072 1 c) 1971, 19 sanplas
ppa I d) 1975, 20 saaples
e) O.OSO * or - 0.040 I •) 197C, 19 saaples
ppa I f) 1977, 20 aaaplea
t) 0.062 * or - 0.021 1
PPB I 100-141 lactatlng VOKE, 2 aonths
e) 0.052 * or - 0.025 1 after delivery- Besidents of Osaka
ppn 1 Erefectare, Japan, Taxied diets and
1 ctTironnantal coclitions.
t
t EISTICIOES; DHIDSII: CBG1IIC
1 CBICBIW! COBPODiaS; Ja»l; UOIIS;
1 tlCTlTIOI: BIIK; BtOlCCDBIIUIOl;
1 EOITCHLOBIB1TED EIPBEITLS
1
3.93 ppb I 2 positive speciBeas
seosetric F
1 (xegaaBt «OB«B, linllat in
t aocioecoaoaie level and dietary
1 habits. Bo occapatioaal or
1 tcciflental eiposare. Lacknon, InJia
1
1 PIStlCIDZS: CBLOCIIinO E1DBOCIRBOJS;
I CEIOBIXB oseinc coapovras; HDD; DDE;
1 DDI; IIBIl: PSICUJCI; 1BBIOIIC
1 IIOID: PllCIITa
i
SEFEUBCE


Takashlji, T.
ratanabe, I.

Tosnida, S.

KnnitaJ «.
19T9
International archives
of Occupational and
Xnviioaaeatal Health
03:1-15





Saxena, B.C.
Sett. T.D.
Baha-laa, P.I.
1980
International Journal
of inviromental
Analytical cheaistry
7s24S-251



I
                                                                                                                                                                                             u>
                                                                                                                                                                                             NJ
2-B«t«BOl,  3-mottrl-
S98-75-*
C?-H12-0
If 8S.1S.    128 C
1 TISSUE
«CM
Breata


I
1
1






1
1
EIPOSORS iom

1
1
1







r
i
i
1H1TTIC11
HRB09
GC-BS













g»BR
or cists
54 (387
staples)













1 BUGS
lot given













9EU
0.378 ng/1
Seoietric













GIIIM1 IVFORBITIOI
Beaaoxed at 2S C and 760 mm Eg
15. 5f occurrence
Io>«c and upper one-Siqna Units
0.123 and t.16 ag/1

Bialtbv, 11-35 TX old, noBSBoklnq,
nrtan blacks and cancasians.
CaieBgo, II. Pioidly controlled
ciperiaeatal coadltioas.
f«UT8: iicoiots; HI.IJOIS: IDOITS;
CP.LCBIUTZD BTDBOCtlBOIS; TOUTILE
CteillC COIFCUIBS; 8I11TB BIHSCS:
I'RIUTIOli SSTAEOLISI; BETaBOIITISi
tcfouTioii riposai:; IBB lit JEHS

misstcs
Kcotoszynski, 3. 1C.
Brnnean, 6. If.
C'Keill, H.J.
1979
Jonrnal of analytical
Toxicology 3:225-231










-------
2-Jataaone
78-»3-3
C4-B8-O
If 160.27. BP 74.57 C. TO 71.2 H Iq «t  20 C
tlSsOS

•««s
Breatk










4646
Breath












EIPOSOBS BOOTS



























1IUTTICIL
nrrHOD
8C/BS











SC-BS













•naiss
or cisis
8











54 (387
sasples)












Mies

lot det«ct«d-60.0 agykr








•


lot 9ir«n













nil

1«.« ag/kr











3.6 ag/1
Geosetric












6ZBZUL iiroBHTioi

ccaiomd related to norul
ictabollaa. lo other detalla gives
Cryoqeaic saapliig teekaiqiM.

Dcaltkr a Hilary and clTlliao
«iFlOT««s. U.S. Hi Forc« School of
Mz«spac« a«Jlciii«. aqes 23-»7 yr. 3
stokers.
imnis: CBICIIIKBI BIDBOCIBBOIS;
cnoilK oseuic coatonns:
CHioBOBiiiiwis: nnoiiis COHJOOMS;
IIHTB: HCOBOLS; THIS; 1 DOITS
Iiasnrei at 25 C ud 760 •• Si
53.2* occvrrcmce
Icier aad spper one-siqaa Halts 1.48
and (.8 aq/1

KcaltkY. 18-35 jt old, aoaiaokinq.
actaa blacks aad caacaaiaaa.
Cblcaqo. 11. XiqidlT coBtiollcd
eipcriMatal conditloaa.
»(UB: IICCBOIS! ILIIIOIS; 19QITS;
CEICBIBKZB FIDSOC1BBOIS; T011THE
ctsanc coBtooios; aztua BIUBDS:
HBaUTiev: aniBouss; BIHBOIITES;
tcfoiKioB inosm: IBBIB utis
SETCBIBCI

conkle, J.P.
Caip, B.J.
Selch, B.E.
197S
arckiTas of
Znviroaaaatal Health
30 (2) : 290-295





KiotosTTH«kif B.K.
Brvneaa* 6. 8.
O'Helll, B.J.
1979
Journal o£ inaljtlcal
Toiicoloql 3: 225-234








                                                                                                                                                                                              U)
  2-Bataaoae.  3,3-diaetkyl-
  75-»7-8
  C6-B12-0
  •I 100.16,  » -«».8 C, BP  106 C at 760  aa   18-35 TC old, sonaaoklng.
otliB blacks aad caocasiana.
Chiciqo, TL. Blgldlr controlled
eipcrlseatal coadltloas.
HIITI; 11COBOLS; IUIIOIS; JDTJITS;
CllOBTIaTtl ETOBOCHBOIS: fOltTILB
CS«»TC COIFCOIDS; BB1LTB BaZUDS;
iiamTic": lETteoLisH: sziiBotms:
EOfOUTIOf IXPOSQIE; H1B1B UBtS
BtrEBIBCE |
1
1
Ktotoszyaski., B.K.
Braaean, G.H.
O'Helll, H.J.
1979
Journal of analytical
Toxicology 3:225-234









-------
    	 IH-
    &!«-«»-«
    c»-ie
    Bf W.12, I? -105.55 C,  BP O.S8 C.  Tf  1M2  u
                                                    «t 21 C
tlSSIf.
««(t
Breath









EltOSTOJ BOOJE











HlIttlClL
BITHOB
ec/ss










IDWS8
or CASES
t










111SE
lot d*teeted-»0.0 »9/«r










Bill
10. S toyhr










GIBtlal imrOtBtTIOI
Ccifonid relate.1 to mraal
•etaooli*!. lo other ieti.ll: aitn
Crjoaeaic saaplXaa technique.

Realthr lllitary «ed eiTlllaa
eiploreea, tt.S. Ur force School at
lermptc* Betticiae, a«es 21-47 jr. 3
»ok«r*.
ItltntS; CBIOUHTED mtOCUlCIS;
cfltosiiB cieinc cospomiDS:
tiKJtosEtztwzs: riaotiix costoatass
mattes
Coakle, 3.1.
Caep, B.J.
Velch. B.E.
W75
Ireaivea of
foTironBCBtal Health
38 (2J *2*0-295
•



   2-Bit«ae.  til-
   5»0-1»-1
   C«-B»
   II SC.12, IIP -1M.I1 C, EP 3.7 C, TP 1»10 u Bq at 21 C
Tissue
*«*•
Br«ati


1







ItNSVH BOITB












1 IIUTTICU
mtoa
ocyss











•tJBBIB
OT C»S!S
a











t»ei
lot d»tect«d-23.0 «4/hr











Bill
4.8 09/hr











GUtBll IHOSI1TIOI
Cciroiid telat*! to Mtul
Mttholtsi. lo other details given
crroouic nmtl±ag teekaioie.

leiltaT •ilitarr and oliilian
eeplojees, U.S. lit force School of
lerospace iredicia«. «3« Z3->7 rr. 3
stokers*
llltniS; CBICEI»«EB BTDSOCtBSOilS:
cEioBtiB otetnc conotmst
ciiotoiiizivES: renoaiR ccnro0»!>s:
t1Z»l; tlCCfiOU; THIS; UDITS
tmsttct
Comtle, J.I.
Ca«p, B.J.
leleh. B.I.
197S
>CCbiT«> Of
Inriioaratal Health
30 (2)! IJO-295





                                                                                                                                                                                          OJ
                                                                                                                                                                                          u>
2-Etarl-l-P«>t«eoI
C7-BM-0
Bl 114.23, BP 16»-16t C
                       postings IB CBWUTIE).
( TIS5V1
1
1
1
1 treat h
1











I BirOSDJ! IOOTI
1
1













' "SCToJ"
i
1
ac-iis












IOBI3B
or cisis


S» f387
niples)











	
1I1GE


lot ?iT«*












'EH GBIIBI1 IlrOIHTIOB


0. 27i 09/1 Btained at 25 C and 760 la Bif
eeoaetric | 3<.9t occurrence
1 lover ud epper ooe-slga. Halts
1 0.14* tad 9.729 09/1
1
1 lealthT. 18-35 ?r old, nomaoXtnq,
1 vrtan blacka and cavcaaiaia.
t Cbicaga. TI. Blgldlr coitrolled
1 tip«riieat*l cotlltloti.
1 tlllTT; UCQCOIS: IlLIHOlSi IOOLTS:
1 CflCBISHEB BTDSOC1BE01S; VO11TI1E
( CECaflC COBPCCUDS: BU1TB BltlRCS;
1 IWUlTIOIt BCTaBOLISS: BBIlSOlITSSj
I »CPOI»TIO« BlfOSOlB; IJB3H 1BEAS
1
EEfEBEIC!


KrotosTTBali. 9.1.
Bmneaa, G.R.
C'leill, B.J.
1979
Jourul of loalrtical
ToilCOloqT 1:225-23*










-------
2-MraiM
!»2-»3-s
I* 8».16. IP t«1.3S C.  BP 68.5 C
TISSB!
»651
Breath










tXfOSOBZ BOOK












luinicai
1ET8CO
OC/HS











•mass
or cists
8











MKZ
lot detected- 17.0 ug/kc











«a»
«.0 ag/hr











GBIIUL xiroMitiov
ccafoatd ranted to aona.1
MUbellM. lo other detail* giwa
Cryogenic ailpllao: tackliqo*.

B«ltkf illltiCT u4 cifillaB
(•plains, o.s. itr Torco school of
ictaaiwec H«4icU«, «qes 23-»7 yt- 3
stokers.
tllZHES; CBtOEIIlTJII HTDXOCUBOMS:
CBIOMIB OI61IIC C08PODIBS;
cmcionitziis; rtnoBUE COBPOIIDS:
II1HI; ItCCBOtS; TSIU: UDITS
- 	
taisact
Conlcle, J.P.
Ca«p, B.J.
Belck, B.t.
1975
IrchiT** of
IiTicoBMital Health
30 |2) : 290-295





 2-Octaool
 C8-B1S-0
 BI 139.2, "P -31.6 C, BP 178.5 C,  TP 1  •• Kg at 32.8 C
I 5ISS1!
1
«C52
Breath









•«53
Breath












IlfOSOM BOWS


























inimciL
"r™o»
«/BS










SC-BS













BWBHI
or CISES
8










S» (387
staples)












B1«GJ

lot detected-98.t uq/tr










lot given













mi

12.3 ug/hc










O.M ng/1
Geoeetric












etnui nreiunoi

Ccifoigi related to Docaal
netabolise. lo other details given
Cryogenic stapling technique.

Maltiy ailltary aad ciTllian
eaployeea, B.s. »lr force School of
lerospaee Bedlcine, ages 23-47 yr. 3
IIHEISS; CBlOBlniTBD HTPBOCiBBOBS:
CELOBIHB OBfiUlC C01POUBPS;
cnoBoanzztu; rLiOBiis COBTOVIDS;
HIITB: 11CCBOLS; THIS; 1DD1TS
(ensured at 25 C and 760 an Bg
31. 31 occnmice
toner and of per one-siaaa liaita 0.26
and 3.1 Bq/1

lealthy, 18-35 yc old. noaasokieg.
nrfcan blaclcs and caticasiana*
Chicago. II. Blqilly cant tolled
eiptrieestal conditions.
IB.EITB: I1CCBOIS: IUI10IS; IDdttS;
CBLOSIHTIE BTDBOC1B30BS; TOUTILE
CIJIWIC COBtCOIDS; BltlTB B1Z1BD5;
11BIUTICI: BETltOLtSS; aETlSOLITBS:
fCPOLiTiot ZIPOSUBB: DBBIB iitis
tmntct

Coakle. J.P.
Caap, B.J.
telch. B.».
1975
Itchlves of
ZnTlronneatal Health
30 (2): 290-295





Ironean, G.M.
O'Helll, B.J.
1979
journal of analytical
Toxicology 3:225-23*









-------
     2-Peattaoae, a-mtkyl
     108-10-1
     C6-B12-0
     B« 100.2. HP -S».T C. IP 116.85 C. TP 16 ee
1ISSVB

•S5»
Breath










txtosms torn*













iBunxcii
BETSOB

ec/HS











BIB an
OF CaSES

a











BlBGB

Bot detected-2*. 0 ag/g











IE1B 1 email. IBPOBB1TIOB
1
I
1
».2 ag/hr i ceapaaad related to aoiaal
1 tetabolisa. (o other detail* ?iiea
j Cryogeaic aaapliag techaigae.
I
1 Bealtk) ailitary aad cUiliai
I eaployees, U.S. air Force school of
I lereapace BediciBe. ages 23-«T jr. 3
t fiokecs.
1
| tlBtini; CBIOBIIHEB BIOBOCUBOBS:
( cno*in orsiBic coitoans;
| CBtOBOtEBZIBfS: flOOBIBE CORPOITBOS:
t tBIlTI: 11COBOLS: TZI15: ID01TS
SEFEBnCZ

conkle, J.P.
cup, t.a.
ire lea. 9.E.
1975
ircni»« of
ZBTinvaeatal Health
30(2|t290-295






    2
-------
2,2-Oia«thrlactaBol  (to
2310-14-1
C10-I22-0
11 158.29
                                 t> caiman .
nssn
*«S7
>t*atk










moson toon












alaimcu
RETBOD
ec-as











ioun
or casts
5* (3*7
staples)










1MG1
lot 9l**B











asu
0.317 ng/1
MOM trie










cuttii iiroiunoi
laatsni at 25 C aad 76« la Sg
31.0* oceariaac*
IOB«T aad appar oaa-Slou lislta
0.109 aad 0.915 *oyl

ttaltBT. 18-35 TT old. BOBaaokiaa;.
ittai Macks aad caacasiaas.
Cklcaga. II. Flqldlr coatcoll«d
«xp«rla«atal oaadltioaa.
mm; >icoioisj HUMUS; IDIHS:
CU.CIIIIT1D BTDBOCIIBOIS; TOIITH.!
CIBHIC COBPCT1D3! BBILTH BillBtS:
IlBiUtlO*: BMISOHS!; HgT>9OlITlS;
ICVOUTIOI IINSOH: OBB»» ISEIS
-
Krotasxiaakl, B.X.
Bnneaa. a. I.
C'Mill, B.J.

Journal o{ taalftlcal
Tozleoloaf 3:225-23*






 I.2,3,3-letr»»»tiTlh«i»ii« (lo postings IB CBCTUI1].
 13«7S-81-5
 CW-K2
 81 1*2.32. B> 1«0.3 C
TISSUE
Bnatk











EIPOSOBI POOTI












llllTTICIL
RETROD
GC-KS











tnasis
or osxs
5* (387
aaaplcs)











MI6>
lot giT«n











Btil |
1.3 aq/1
GeoMtrie











GBIIHL IITOMITIOI
e«a»t«4 at 25 c aid 7CO at Bq
lenc au4 appac oac-Si^aa Halts 0.35
aad *. 8 «q/l

KilttT, 18-35 TT old. BoaaaokiBq.
aztaa blacks aad ca>ca*iaaa.
Cklcaqo. 11. BiqidlT coatzoll*!
BBHTB: aicciois; nmois; IDOIIS:
CIlOBTlaTn BIDSOCltBOIS; TOUTIlg
Cf3i«ic coiicnns: SIII.TB BIIMBS;
HIlttTKl; F.3T1BOIIS9; BETaBOlCTIS;
EOPDUTIOH tIPOSOIX; T>SB11 UEaS
nFZlNCI
KiatoaxiasU. B.I.
o'i«ill! aljl
1979
Joataal of aaalrtical
•torloolo^i 3:225-23*







                                                                                                                                                                                             U)
                                                                                                                                                                                             --J
  2,3,3-TriaBthTla«xaa«  (lo postiags in CBZflLIfEl.
  C9-B2-O
  t»  12«.2!. It  137.7 C. TP 10.1  aa H«j at  25 c
1ISSOE
MW
Sratk











EIPOS9BE BOOT!













nurricn
BETHO9
6C-SS












lOMSt
or cisxs
5* (387
saaplas)











nisi
lot giT«a












Sill
0.730 ng/1
Seoaetcic











6IIIBU IiroiHHIOl
e«aaar«4 at 25 c aad 760 aa tq
18.*' occarr»e«
£c«*c aad upper ona-Sloaa Halts
C.U7 aad 3.62 aa/1

Kalthr. 18-35 yr old, nonswikiaqj
aitaB blacks and caacasiaas.
Ckicaqo. Tl. ItqldlT cant colled
ciB«rlB*Btal eoaditioas.
BiiiiB: iiccBois; miiois: inoits:
cncnitTZD ETDROCltBOlSj tOUtllB
CE61ITC COBtCtTIOS: BEIHB BIHSOS;
IIB1UT1CI; alTlEOLISS; BElaBOtltZS;
BZ7EIEHCE
KOtOBllUBki. B.K.
Bcnaaa, S.I.
O'letll. B.J.
1979
Joaraal of aaalrtical
Toiicoloqr 3:225-23*








-------
     2.3.3.*-T«traaetarlpeitaae  {*> postiaas la erasure).
     167*7—38—9
     C«-B2-O
     (1  128.25.  BP -102.123 C, IV 1*1.551 C
fisstrs
»6SO
Breath












Eiposvss aooit














IHttTICII.
BBJBCD
ec-B5













BOBBSB
or cjsu
5» (387
•aa pics)












MK>
lOt ?ina












1
III!
0.39* «9/l
Geoaetric












ezizsiL nroBUtioi
E*a«nr*4 »t 25 C aa« 7«0 « Bg
10.»* ocetrreac*
Imer and opper oae-Sl«aa liaits
0.113 ana 1.41 ao/1

Kattlif, l»-35 rr «1*. oou«o)ti»9.
acfc*i blacks aad caicasianfl.
Ckicago, II. SlgiSlT controlled
ar«a at 25 C *n4 7*0 aa H<)
«. It occarreaca
lowr and upper one-sigaa Halts
0.020 sad 0.712 aiHiTic>: RRIBOUSB; BIKEOITTISJ
tCPtn»TIO» -IPOSBBE; DBB1B UtlS
1
BlfMMCI
Krotosx^aakij B.K.
Bruneao, e.g.
O'Veill. S.J.
197t
Journal of analytical
loJicolegy 3:225-23*







1
	 1
                                                                                                                                                                                        U)
                                                                                                                                                                                        U)
                                                                                                                                                                                        CO
3-Heptanow, 5-aetarl-
5*1-85-5
CS-B16-0
F> 128.22, BP 160.5 C, TP 2.0 •• Bg at 25 C
1ISSOB
•«62
Breata












nvosm! BOOTS














mi men
BETIOD
OC-BS













ITB9BIS
OF CUES
5* (387
Maples)












I»E>
Bot firen













BB1B
0. SOS BO/1
seoaetric












GTiiEiL ziroaaiTiov
-
leaaared at 25 C and ISO aa Hq
5.27 occvzrence
lo»«r aad upper one-Slqaa liaits
0.200 aal 1.27 IKJ/1

Bt«lthT, 19-35 yt o!4, aoasaoklav.
ittan blacks and caacasitns.
Chlcaqo, II. sioUlr COB trolled
eiperiaeatal coaditlona.
mm; ucctois; ituiois; IDOITS:
CEICBIWIT'D BTDBOC1BBOIS: 10HTHS
ClGllIC COttCOtDS: BEtLTl BitlBtS:
UBIHTIOH; (mkEOLISB; BIT1EOLITSS:
icponnoif EiposaBi: 
-------
3-Bexanona. 2,«-diaethTl-
i86»i-7o-e
CS-H1S-0
RI 128.21. !F 1(5 C
TlSSm
•663
Breath












ZKtOSdBZ E001I













ilaLTTICal
aiTBOD
SC-HS












IOBBIS
or cisss
5« J3B7
staples)












BaISS
lot giTen












BUI
_
0.311 ng/1
seonetric












61)1111 IirOBBlTIOJ
Eeasnred at 25 c and 760 ia He
25. 3% occurrence
l««er and npper one-Siqaa liiits
0.134 and 0.«9» noyl

BaaltkT. 18-35 -r ol4, nonsaokinq.
art an blacks in a Caucasians.
Chlcaqo, II. ElqWlT cOBtlollad
«pcrii«>tal coadltioaa.
EiUTH; 1ICOCO1S; IU.HOIS: ICO ITS;
cnoBintiD noiocasmis; SOUTHS
C»OJ»IC COBPCOSDS: 9SJITB H12»SES;
IIIaLHIOl; inaEOllSH; BITJBOIITSS ;
tCrOLtTIOl IIP030IB: 3BBi» 12B1S
Bimnci
Irotosijuslti, B.K.
Braneaa, C*8.
C'Mill. I.J.
1979
Journal of analytical
Toxicoloql 31 225-23*








 52B-97-2
 C€-B12-0
 H« 100.16. BP 1SS-15T C
TISSUE
•66 1
Snath












MPOSUJ! M)BT»













tSILTTICll |
BBTBOt |
1
SC-IIS












iBBBta i
or cisss t
S« {387
saaples)











1
BUGS |
1
lot given












Bill
1.1 »g/l
Geometric












SIIEBaL moiliTIOII |
1
1
t«as*r>a at 25 C a»d 7*0 ai Bg
Ifi. 3T occurrence
loner a»a offer oie-Sigaa liiits 0.28
aid 4.3 no/1

Bcaltay. 18-35 Tr old. noosaokinq.
oTtu blacks ana caocaalaoa.
Ckicaao. It. Biqidlr contcolled
€ipccia«iital conditions.
ESt«TH; alCCBOlS; IUIIOI5; tDOITS:
CBIOBIU1ID BTBBOC1BBOBS; »011TI1B
CBCtlltC COBPCOSB5: BEaLTH B1I13CS:
1IH1HTI01; IWTIBOLISB; KSTIBOLITES;
EC?aHIIQ« IITCSOIE; OBBH IBEIS
5ETI8EBCE
Krotosmskt, B.K.
Eraneaa. G.«.
C'Seill, H.J.
«79
Journal of tnal^tlcal
TOilcoloqy 3:225*23*








 3-PentaBoae,  2-«ethrl-
 C«-B12-0
 B»  100.16.  BP 1K.S-115 C
itsso-

a66-i
Breath











zirasma scan














allLTTICal
BITBOB
SC-BS












IVB9EB
Or CaSSS
5« (387
saaples)











BUGS

lot given












isTi j

0.86 ng/1
3e one trie











GElIBal XITOStaTIOl

leasgrel at 25 c and 760 aa Bq
31.3V occurrence
lever and upper one-Si gaa liiits
C.023 and 0.33 nq/1

Bealthr. 18-35 yr old. no»nokinq.
artan blacks and caacasians.
Ckicaqo. II. Siqiair conttolled
eiperine-tal conditions.
fUMTH; itCCBOlS; IHHOIS; 191I.TS;
CELOBIWHTED CTDBOCfcBBOBS; TOX&TXIE
CtGlKC COIfCnDS: BlllTH BltARDS;
I«B»HTIC«; HE/tatoLis^: SEHEOLITIS;
tCfOLlTIO* IIMSOttE; H9B1J IBEtS
BETEBEBCE

K 0
Crimean. G.g.
C'Heill, B, J.
1979
Journal of analytical
Toxicology 3:225-23*








-------
    1M7-20-S
    C9-B20
    •* 128.25. HP -33.11 C, (P 1*6.17 C
iissni
•««
Braatk











nrosmtE IOBTB













iiumcu
sc-ss












or C1S2S
5* (317
aa>fltaM do posting* la CBgnni).
   422-W-1
   C»-B2-0
   II  US. 25, II  1»0.« C
Ttsm
«««7
Snatk




1








titoimt scant















H11TTTCI1
nsrnoD
OC-gJ














imm
OF cms
M (3*7
saaplca)













IMCI
lot 9! van














BUI
2.J »a/l
6«OB«tric













e:iicii iiroiuiioi
E«amr«d at i5 C a»4 7 SO •• B«
27* 7t occvmnc*
ICTHK ac< opp*r oav-slgw lldts 0.98
• tt 5.* *4/l

Maltlir* 11-35 rr old, BoxaioktiKi.
mt» blacks and eaoea»la».
Ctleaqo. II. tliltlr contcoll*4
«ip*rlnotal conditions.
etziTB; itccms: iirnois: »ous;
CnatHHID ETDlOCtlBOIS; IOI1THS
cieiiic cospou»ns: SSIITH BIHBDS;
IlltUTIOf; RRtEOlISX; «!1EO1ITKS;
iopnt»no» ixrosmR: »>» IBIIS
i
BEmncz i
!
Kcotoaxj-nati, S.S.
Brao«ao, C.I.
O'latll, S.J.
1»79
Janrinl of Inalytical
Toilcoloqr 3:225-23*









                                                                                                                                                                                            U)
                                                                                                                                                                                            *-
                                                                                                                                                                                            o
4-MptaaoM
123-W-3
C7-BU-O
BW 11*. 1*. Bt -32.6 C, It 1M C
nssn
»«€8
Braatfc












sifosffBS soon














inirticit
BITSOB
GC-BS













Boaia
OF CJSJS
5* (387
saaplM)












SHIS
Bat giT«a












-
1 B3H
1
0.07* BJ/1
Je Metric












cEiiBtt mossinoi
B«aaar*4 caaeasiaaa.
taica«o, 11. >io.lily conttollal
«tp
-------
t-leptaaone
123-14-3
Cl-iW-O
Bl 11». 18. UP -32.6 C, BP 1« C
                                                                                     (CORIIVBD)
ITS SOB
»«»
VClM






nposm BonE
Serial






lIUITICtL
BROOD
OC






or CUBS
a» IS
b> «o






BIKE
4) 0.01-1.5 sg/g
CreatinlM
b) 1.5-3.7 sj/g
creatlBiaa




_.
am
a) lot gives
b| lot glres






Gil till XIFOIBMIOI
'
•) Costrola
b) forkers eiposed to chloropheaols
Inkers lit h«rblcll« laaufaetirlna
(lint*.
BfSBICTDBS; HBOSTMU M.1JTS;
cccaptTioiu Btzugs; rssriciDis:
icmuTiof Bitosoii: CBLOIIBI OBGIIIC
ccBPovns: IBKOU: cmoi: mm
BZnBBlCB
T«B Boeotian, P.B.
n«Ln, i.i.
1980
International ireUvu
of Ocnpatiaoal and
EiTironaeatal Health
•5:57-62


C12-H1*-*}
It  186, HP  300 C

•«TO
Blool,
plaan








MTHOO




or cisss
1


-
BIIGE
•ot glTea



BEaB
0.133 »g/l



CEB1I11 IBTOIRITIOR 	 j
C Aayi after 50 •! dilited grancoiie
39 jt «ia, aildto atteipt.
El»p«««, r«nl f allot*. fallUq
forces Tital capacity.
Imeitel urea, eteatliiie.
Etotelanrla, hrallie east* IB itlie,
(eiiUlar ofaeities.
aziBICTDES; tBSTICIDBS; BLOOD PtlS'Tl:
S1ICTDI
	 	 	 	 	 	
*S*BBBICB
Eose, J.D.B.
1990
Lancet 2(1200) :92*



                                                                                                                                                                                        OJ
a.T-Bethanolndan.  1,2.»,5,6,7,».8-octachloro-1.2-ep«T-3«.«,7,7a-tetr«tiYdro- (( CD
2,S-!)eth»o-2B-iBdeso(1,2-b)oxirese,  1a.2,3.s,S.Ca.7,7-oct«cUazo-1a.1b.S.5a,«,«a-t
 26880— a8— 8
                                                                                             It
    m.n

•671
111k














BETBCn
GC






OF ClSSS
	
1««





_____
ins:
75.4-11S.3 ppb





. 	 	
8E1I
95.8 * or - 195.1 ppb






GE«tB*L HTOB9ITIOI "
Ccipited OB fat aallit«J basis
lanoe ot Maaa for all geoqiapkie
< agios*

cinio siHisj minis; mi;
ceiptBuiTE mmriois; caioain
CfSHIC COBPCITIDS; HSIDBII;
VISTICIOBS; tlCTanOI



IERBETCE
"
Sarage, E.P.
Eeefe, T.J.
Tessarl, J.D.
•heeler, a.«.
applekaaa. T.E.
Goefl, E.I.
ford, s.i.
1981
laerlcan Joarnal at
Ipilesiolog}
133 («) :«13-«22

-------
a.7-!!etlianoina'an. 1,a,5,C,7.8. 8-heptachloro-2,3-epoxT-3a.a,7.7a-tetrahvdro- (8 CI)
2,5-8«thano-2H-iideiio(1,2-b)oxireie, 2.3.B,5.«,7,7-heptaehlora-1a,1b,5,5a.6,6a-hexahvdro- (9 CI)
1024-57-3
C10-BS-C17-0
II 389.32

TISSUE
4S72
Adipose
1673
Adipose
1
1
1
1
4674
Hi Ik
1
1
1
•675
111k
ETPOSOBE BOO!


Ingestton

AIUTTICAX,
HETBOD

GC
GC
GC
BOBB5B | BABGE
0? CASES |
1
1
1
1
1
1
1
1
1
1
f
1
1
1
1
1
1
1
1
1
1
1
1
60 | <0. 05-11.? 5 pp.
1
1
1
1
1
1
21 I » 0-0.296 ppl
24 1 b) 0-1.902 ppl
15 | c) 0-1.002 ppl
45 I d) Mot given
1
1
1
1
1
1
1
1
1
1
1
6 | 66.1-128 PPB
1
1
1
1
1
1
SB»» | GIBIBAt IITOSBATIOB 1 EEFEBIHC!
1 1
1 I
1 1
I Scviev f Deichaann* V.8*
I | McDonald. I.E.
1 Expose! persons IB the United states. I 1977
1 the Netherlands, Sweden, Israel, | Ecotoxicologv and
1 Japan, BSSB. Polaad, Geriany, India, 1 Environaental Safety
1 Enlgaria, Pakistan, Austria. 1 1:89-110
1 1
1 deported cases of hypertension, 1
I elevated serai cholesterol, abnanal I
1 EIGs, or iapairaent of nenrcnscular 1
1 fnctioB after acate exposure to 1
I calcinations of pesticides, but lost I
1 Icng-terB occupational exposare. j
1 1
1 lOSTBit; BOLGABIA; GEBBAii; noil: i
I ISB1EL; JAPAl; HETBESIAIDS: PAKISTAI; 1
1 tcLiio: BOSSII: SIEDEI; DIIIED i
I si »i is: IDIFCSE nssijJ: BLOOD: BLOOD I
| FIlSBl; BIOCC SEflOB; EBTTHBOCTTES; I
| IIDKOCTTES; BILK; OBIXZ; BETI5W; I
| BI11TH B1Z1IDS; OCCtlPlTIOIU B1ZUD5: 1
| FCPOUTIOM BIPOSU3E; HIOPLJSBS; |
| FESIICI3IS; CBIOBIIE OEG1IIC 1
| CCBPOUUDS |
1 1
I 1
0.38 ppa f Peripheral kidney fat, routine 1 Oejonckheere, ff.
I cathological exaaiaations I Stearbant, 9,
I 1 Terstraetea. E.
I Iqes 6 ao-92 yr. Belqiua 1 Kips, F.H.
| | 1978
1 EiiGloi; BIOPSIES: IDIPOSE TISSUE: | Toiicological European
I eio*CCOnniTIOB: PISIICIDIS; DVD; 1 Research 2(21:93-98
| ttl: DDT; DlttDBIl: BEPTtCBLOR I
| ffOHDt: BtXlCtlloniSEIZEIl: LI (DIKE; |
| CELORUB OBG1HC COflPOaiDS \
1 ' ^
1 1
0.017 ppa I a) Baral anthers, fat basis 1 Pozo Lora, B.
0.051 ppi j c) urban Bothers, fat basis I Herrera Barteacbe, ».
0.035 pps | c) 111 Bothers, fat basis I Polo Tillar. L.n.
0.0003 PPB 1 d) 111 Bothers, nhole ailk basis 1 topez-Giienez, I.
| Cata for son of all pesticides and 1 Jodral Tillarejo, 
                                                                                                                                                                                          l-o

-------
«,T-Bettanoindene,  1,t.5.6,7,8.8-heptacliloro-3a.»,7,7a-tetraoTdro-  (8 CI)
                        I.I.S.S.T.a.S-beiptachlaro-aa.a.T^a-tetraliTaro-  (9
«t 373.35, Ht 95-96 c,  Tf 3TIO («-») H  Bq «t 25 C
Tissue
«67«
"ilk











ZXtOSTOE B001! 1
tngestion












a>U.tTICU
MTtBOB
GE












R09B3B
OF C1SES

b) 2»
0 «5
d) «5









IMS!
a) 0.405-10.823 ppa
b) 0.615-11.686 pps
c) 0.1105-11.686 pps
d] lot given










a) 2.556 ppa
b) 2.«62 pps
cl 2.505 pps
d} 0.0390 ppn









GtltElL IlrOSIlTIOl
-
a) Bural lathers, fat basis
b) Urban Betters, fat basis
c) 111 eotaers, fat basis
d) 111 eotaers, vnole ailk basis
Data for svn of all pesticides and
^caparisons vlth valoes of other
investigators given

•ntslnq notnecs froa Cordoba region.
Sraia
SFllI: IBDtTSj BILK; CSLOBIH OieiflC
CORTOraDS; EISTICntS; KSBICUtTTOI:
CIIU 11I1S: OBBII tBElS
BEfEIEICE
Pozo Lora, B.
Becrera Earteache, a.
Polo Tlllar. L.9.
Lopez— Ginenex, ••
Jodral Tillarejo, S.
Tglesias Perez, J.
1919
Sevlsta Espanola de
fedlatria
35 (206): 93- 110



 5-»ortora«»«~2.3-4l»ethanol. 1. »,5, S.l.-T-heiictiloTo-. cyclic s«ltlt« (8 Cl>
 «,9-Ktbana-2,K.3*be«zoa.lai*tiii«paii, 6.7,«,!.1l),ia-»eiicla»ro-1,5,5a,«,9,51-terahiiro-, 3-0tide \9 CI)
 II5-W-7
 C9-B6-C16-03-S
 •• •06.*').  flt  106 C,  n 1I10CI-5)  as Bq at 25 C
Tissni |
1
vhole

EXPO&llfiS RODTB


mtmciL i
IHTHOD |
GC-EC

or CISES
a) 35
b) 12
0 36
d| 12

1U6E
a) lot detected
b) lot detected
c) lot detected
1) tat detected

nil
a) lot detected
b) lot detected
d lot detected
d) »ot detected

C.IIEUL IIIOSBITICI
a) Tniodan I, Love canal residents
bl Taiodan I. volatteers
c) Ihiodan II, Ion canal residents
i) Tbiodan II, vol«ateers
lisit of leasnreaekt, 0.23 n<)/q for
•thlodan I and 0.32 aq/q for ThioSin
II
CloaelT aatcbed, slanltaneoai control
ta spies *ere aot provided for
aaelrsla alooe witk those froa tie 36
lacklmq neaninqfsl control or
literature data relative to the
significance of the lo* residues
fcnnd in the field saaples analvud,
DC definite conclusions can be dram
fees the results reported.
lesiieats of tew Toil. Controls,
eiplovees of the laviranuital
Erotection Iqencr a«d university
itid«9t8. fcrth Carolina.
Ill T01K: tcm cuoilll; WOOD;
Bi»aenm BROODS; CHICHIE oiGinc
CGBEOanS; CtLOBOSElIUM;
cipmns; roeounoi EIPOSIH
EIIIBESCI
Bristol. 0.».
19BO
II1-«00/1-80-036, ao
pp.
1
                                                                                                                                                                                             OJ

-------
  345
DRUGS

-------
 (1, 1*-3iphenTlJ -m-bntanoic acid, gasea-oxo-
 3H30-85-5
C16-BU-03
RR 25*.3, at approx 180 C
TISSUE
•678
Blood,
sen*
















Urine


















	 -
EXPOSURE SOOTE
Ingest ion
















Ingestion,



















1 Hit men L
HETHOD
HM.C
















HPLC



















HOBBSB
OF CtSSS
26
















26


















-.
B1RGE
a) Rot giT
b) Rot giT
c) Hot giT
J) Rot giT
e) lot giT
f) Rot giT








'







a) lot giTen
b) lot giTen
c) Rot giTen
d) Rot giTen
e) Hot giTen
f) Rot giTen


















1 R!ll
1
«) 13.7 * or - 5.3
b) 8.2 * or - 7.9
ag/nl
c) 80.1 * or - 13.2
ug/nl
d) »5.8 » or - 22.5
e) 0.7 t or - 0.3
ag/nl
?) ».2 » or - 2. 1
ug/nl













a) 1.9 » or - 5.8 ag
b) 1.6 » or - 3.6 «g
c) 1.8 » or - 2.0 ig
J) 7.1 « or - 16.8 17
e) 13a. 6 » or - 61.7
f) 5«. 1 + or - «9.7


















Gzimi iiposiiTioR
a) Rornals (creatiniae clearance >80
il/min). measured as unchanged
fenbafem
t) Benallr Impaired (creatinine
clearance 3-20 ml/min) , measured as
fenbufen
c) Roruls, seasnred as
gaiia-hydroiyt 1. 1'-biphenyl]-l-butano
ic aciJ (metabolite II)
d) BenallT impaired, measured as
metabolite II
e) Rormals, seasnred as
acid {metabolite IT)
f) BenallT impaired, neasured as
metabolite It
Peaks, after 100 ng fenbufen, single
dcse
Data also for other metabolites and
ether degrees of renal impairment
51-87 rr old patients and controls.
fasted before and after dose.
ORITED KIRGECR! IBUITS; KIDRII
DISUSES; EICOD SEBIJI; II11GISICS:
IRTI-IRrLinBIIOBT IGERTS;
HTIPIIEIICS; DBDSSJ COKPallKITB
ITIUJITIORS; BET1BOIISB; HETIBOIITIS
a) Rormals (creatinine clearance >80
il/iinl , leasnred as unchanged
fenbufen
t) Benally Impaired (creatinine
clearance 3-20 il/nin) , measured as
fenbufen
c) Rornals, neasured as
qamna-hydrcXTT 1, I'-biphenylT-l-fcutano
ic acid (metabolite II)
d) Benally impaired, neasured as
Ktabolite II
c) normals, measured as
••-hydroirM.I'-tipbenyl T-n-acetic
acid (metabolite IT)
f) Benally impaired, measured as
metabolite IT
Peaks, after 800 mg fenbnfen, single
dcse
Data also for otter metabolites and
other degrees of renal Impairment
21-87 yr old patients and controls.
fasted before and after dose.
3SITED KIRSDCR: iDULTS: KIDRET
EISHSES; 31000 SEBUfl; UllGESICS;
JUTI-IHFLftRHlTOPY KGE1TTS:
IKIPTBBTICS; 9*OGS; CO!IP»B»TITE
ITJItHTIORSj BET1BOLISR; RETM01ITES
SEFESEBCE
Bogers, P.J.
SaTitsky, J.p.
Glenn, 9.
Spector, B.C.
1981
clinical Pharmacology
and Therapeutics
29(1) :1»-«
















Bogers, H.J.
Sarltskj. J.P.
Slenn. B.
Spectar, B.G.
1981
Clinical Pharmacology
and Therapeutics
29(1):7«-|o


















                                                                                                                                                                                         Ul

-------
Icetallde, B-aaidino-2-(2.6-dich!.arpBenyl)- (» CI)
Ecnzeneaeetaaide, I-(aiinoiaino>etliyl)-2.6-dlcliloro- (9 CI)
C9-H9-C12-B3-0
HI 216.11
TISSUE ETPOSIRB- BOUT! JHLTTICJI
BETSOD
•680 tngestion SC-PC
Blood.
cells




(
1

1
1
1
1
(DEIZB
OF OSES
b) 10












1


1
1
I
1
•681 | Ingestion GC-EC a) 9
flood, | b) 10
plana I




f 1
1 1 1
1 1
t \
t
\

1
1
1 1
1 1
1 1
1 "682 | Ingestion GC-EC
1 Trine |


















a) ?
b) 10














i(
bl













IMGE 1.EA. SEBM.L WrOBBmOR

I EEFEBEBCE
1
1
a) 5.6-0.91 ng/al a) Bot given a) Erytnrocytes, 3 and 36 kr wans 1 Seiss, I.I.
D) 11.n-1.55 ng/«l b) Bot given after 2 «g. Initial .easureient 1.12 1 Lavene. B.I.
ng/al at 1 hr
t| Erytarocytes, 2 and 36 br aeins
1 Safar, B.E.
1 Siaon, I.e.
after 9 ag. Initial aeasureient, 5.1 | Loria, I.
ng/al at 1 hr
) Estimated froa graphs.














a) 3.48-0.69 ng/al
b) 8.28-1.31 ng/al


















a) vot given
b} Bot ?ivea






1
1
J
1
1
f
1
I
1
1

Rot given
rot given













a) 29.9 » or - 2.5 *
of dose
b) 3". 3 » or - 5.1 «
of dose











23-59 vr olds, no drag > 4 vk before
study, 100 leg/dar *a diet 3 days.
Ill had c&ronic hypertension without
cardiac or renal involvement.

Reduced blood pressure.

CSOG5; DBDG TBEEaPI; 3IPEBTSBSIOB;
JBJHCEJ BLCCD PLtSHl; OBIRtj BLOOD
ISISStTBE: IBITHBOCTTIS; COBPaBanVE
IftlDlTIOBS


a) Deans, 3. t and 36 hr after 2 ag.
Initial xeasureient, 0.76 ng/d at 1
kr
t) Reans, 2.C and 36 hr after 4 ag.
Initial neasareaent, 3.59 ag/al at 1
br
Cata also given for steady-state
values after 1-3 ag 2!/day.
23-59 yr elds, no drug > D vk before
study, 100 leg/day Ba diet 3 days.
Ill had chronic hypertension vithout


[JUGS; 9RUG UTERI?!; HYPIEIMSIOH;
TB1BCE; BICOt PUSH: UBIBE; BLCOD
IBISSBBB; IHIHPOCITES; C08PH1T1TS
mnjTtons
i) 2 ng dose
t) 4 a<7 dose
72 br caaulative excretions in
unchanged foci.

23-59 yr olds, no drug > » «k before
study, 100 teg/day Ba diet 3 days.
All ha4 chronic hypertension vithout
cardiac or reaal involvenent.

Bedacel tlood pressure.
BIBGS; DIOG TBIBIPI: HIPISIEBSIOB;
tsiBCE: sioor PLisni: OBIBE: BLOOD
;«SS!!SE! fSIIHSOCtTES: CCBPAB17ITE
1 Georges, D. B.
1 flllliez, P.L.
1 1979
1 Clinical Pharaacology
1 and therapeutics
1 25 (3): 283-293
1
I
1
1
1
1

1
I

1 Veiss. I. a.
1 Laveae, D.L.
1 Safar. S.I.
1 Siaon, I.e.
1 loria, T.
1 Georges, D.B.
1 nilliez, P.L.
1 1979
1 Clinical Fharaacology
1 and Therapeutics
1 25(3):283-293
t
1
1
1

1


Veiss, T. t.
Lavene, D.L.
Safar, I.E.
Siaon, i.e.
Loria, T.





























U)
-IS
oo












Georges, D.9. (
nilliez, P.L. |
1979 |
Clinical Pharaacology I
and therapeutics
25(3):2M-293




-------
Acetamide, 2-(p-(2-hydroxy-3-(isopropylamino)propoiy)phenyl)-  (8  CI)
Eetzeenacetailde. 1-(2-hrdroxy-3-( (1-methylethrl) amino) pcopoxr)-  (• CI)
S9122-68-7
C11-B22-H2-03
n« 266.31, HP 106-148 C
TISSUE

0683
Blool,
plasma














9664
Blooi,
plasna








EtPOSUB! ROUTE

Tngestion
















Ingestion










AHALTTICAL
METHOD
HP1C



























HOTIBJB
OF C1SES
12



























BARGE
'
716.1-50.5 ng/lll
















1579-15 nioles/1










SEAS

Hot applicable
















Hot given










GEBIBAL IHPOBBATIOH

Heans, 1 and 24 br after 100 ag.
Initial value, 243.5 tig/ml at 0.5 hr.
sab-fects at test.

flcalthy 20-28 yr olds, no cardiac,
renal, hepatic or absorptive
abnormalities. Bo medication > 15
days, fasted overnight.

Besting systolic pressure negatively
correlated vith drag plasaa level.
r=0.521, p<0.01. Heart rate.
systolic pressure, plasna renln
reduced, correlated with plasoa drug
l«vel. p<0.05.
CflOGS; BLOOD PLASHa; BLOOD PE5SS095;
S COLTS; HOSilCDES
2 and 40 br leans after 100 ig/day

Bealthy 20-3C yr olds, vithin 1OT of
norial velqlit.

9edaced resting and exercise heart
rates. Reduced blood pressure.

CBOGS; SBHDIS; B10OD PLASH);
UTIBTPSSTESSIVE AGEHTS; CODPJBJT1TE
IVALOATIOHSi ADD1TS: BLOOD PEESSOBE
BEPEEEHCE

liner, B.
Hason, H. D.
Carter, C.R.
willoaghby, T. 1.
Kochak. G.I.
Cohen, I.
Bell, B.B.S.
1979
Clinical Pharnacology
and Therapeutics
2«(3):315-325






Johansson, S.B.
HcCall, a.
vilhelnsson, C.
Tedln. J. A.
1930
Clinical Pharmacology
and Therapeutics
27(51:593-601



 cetamlde, 2,2-dlchloro-!i-{beta-hydroiy-alpha-(hydroxynethyl)-p-nitrophenethyl)-,  D-threo-(-)-,  (8 CI)
 cetamlde, 2,2-flichloro-H-(2-hySroxy-l- (hydrotymethyl)-2-(l-nitrophenyl)ethyl)-, (B-(B«,B«)) -  (9  CI)
 €-75-7
 11-B12-C12-M2-05
 « 323.11, (IP 150.5-151.5 C
TISSOE

1«S5
Blood,
plasaa








9S1H
Elool,
serum












ZIPOSIJBB ROOT!

Ingestioo










Inlection













aHAlTTICAL
BETHOD
GC










GC













5DHB5B
OF CASSS
1










a) 8
b) 5












BINGE

11-23 ug/ml










a) 11.2-36.2 ug/rnl
b) 10.0-36.2 ug/ml











(BEIT
9EAB

Hot applicable










a) Hat given
b) Hot given











PAGE)
GEBIBAX IRPOBHATXOH

Initial measurement and 1-2 hr after
50 ig/kg, IT daily as paloitate. 16
nq/il at 6 hr. Measured after 7th
dcse.

After hvpophysectomy, 30 yr old vith
haemophilus influenzae type b
leningitis
AULTS; IHFECTIOB: BLOOD PLASBl:
C?BEBB05?IH»l FLDID: SSTIDIOTICS;
CHOC TOEBAPT
a) Peaks at 15-50 mgAg/day
b) Peaks at 25-50 mq/kq/da?

Ion birth Height infants, 1 vith
tacterial infections, a) Ages 1-8 d.
• t 0.9-2.5 liq, gestational age 25-35
vk, and b) ages 11 d-8 vk, vt 0.9-2.2
kq, gestational age 28-31 vk.
ETHHSTlTaHIA; INFANTS; HE1EOEH; BLOOD
S!B01; SPIHAL FLOID; ANTIBIOTICS:
ttiOG THEBIPT; CHIOEIBE OBGJHIC
CCnPOURDS


BEFEBEBCE

Bensimer, E.B.
Pickering, I.E.
Ericsson, C.D.
Kramer, w.G.
1991
Lancet 1(8212) :165





Glazer. J.P.
Danish, H.A.
Plotkin, S.A.
Samner* J.T.
1980
Pediatrics
66(1): 573-578










-------
c«ti«H«. 2,?-«lrt,lor»-«-(*«

t-'J'r-T
• J?J.1«. (IF liO.S-UI.S C
1
1
i*"*"*" !
fl«U 1
i
i
i
i i
i <
i i
•
Spinal |
I
1
1
1
1
t
1

1 a-kj aroiT-alpti- (



rtTtn
X







sc







kr«lroii»«lt'U-!'-iUr=,-i««. »fcrl)-. :>-t»r»o


,eo.
l or c»5«
1


(
f
1




1 lot applicable






_ 1
-!-)-, (8 CJ|


rifsrsj
•?>i















	 	 _ -





(ti
lg/Iq, li •iiilT a; oil>lta«.

3C TC ill «Ub hanaphllni icflntnza*

•rniTS; IPFBCTTCH; BLOCS PLJSRI;
f*3G vnve«pr ' ~ '

60 lin iftrl dos« f25 itj/kg/dar in 2
?«roi 1«T«1. 10. f nq/al


F!1«SriT»»II; I»Pl»ri; JJHP09"- BLOOD
S[«tH: SPI«»[ fltllB; i«TJ?I01ICS;
CCRPfOMSS f
	 ._._ . 1




««"'«


rr*i«r, V.G.





Gl«z«r, J-p.
E«nish. S.Jt.
riottir, 5.4.
Su>*«rr J.T.
Pediatrics




 Ac*tloo].
               IIPOSOII! ItOOTt
It)9**t ion
OIL
B




• !JII»rB
or c»ses
•) 7
b) 6



XMGI
» 1.65-0.3 tq/tl
b) 7.3-1.5 uq/.l



1 ~ niti
1
1
1
*l Kot gir«n
M Not qir«o



t CFItPfc&t IMFORR&TIC*(
1
1
1
*l Contrail. ! «n1 2« hr «(ttr 200
I 11. 7nitl«] BeReurcMint, O.t ui/il
1 4t t br
u<;/il «t 1 he
Mtiiat«d frci qCKph
•!•»» kq. )2-40 rr oil p«tl«nt».
HlOIfll: HTPrBIE».51C»; FID»II
cisr»sf.TiHTp!«re»;Tr» norics; DMC
iPt»«»T: ne»cor«Lrsis
l r;pc»5»c*
Hftrvvnqt, c.
P»n«q«r. J.P.
HuscKart, J.n.
f»rb»«c)l, n.
>?7?
Journal o( Ciintcal


-------
Icetanillde. 4'-h7dro»y-  (8 CI)
aeetaalde, H-(g/l


a) 14-43 ag/ml
b) 0-5-13 ug/ml
c) 180-9 aayal


(HER
1B4H
7.23 « or - 6.33



139.22 » oc - 64.57
ng/dl



...
a) Hot applicable
b) not applicable


a) Hot applicable
b) 6.7 «g/l


a) Hot given
b) Hot given
c) Hot applicable


P1GE)
GBBBBSL IBFOBBITIOS
textropropoiyphene poisoning
fatalities, alcohol and/or other
drugs in lost cases.
Ccroners cases, ages 16-67 yr,
northern Iceland
ccaa, death.
congestion and edeoa of lungs. In
sone, cerebral edeaa.
[BROS; BLOOD: VBIHB; SUICIDE! DBDG
HOSE: ISE1UD
CeitraproFOXychene poisoning
fatalities. Other drugs found in
peat subjects.
Hcithern Ireland
Coaa, death.
Cengestlon and edeaa of longs. ID
Ecie, ooretcjl vdeia.
tBOGS; BLOOD; OBIBB: SOICIDE; OBOG
HtVSt; I8ELIBD
a) 90-210 iln after 13.93 ig/kg at 2
18
t) 90-210 nil after 13.93 pgAg «t 6
18
Bcnoeipoaental decay. 5s ti Bated fro»
graph.
Bealthy 22-32 yr olds, fasted before
ind daring eiperlnent. Ho drags 1 v*
before stady.
BEOGS; 8BTaBCLIS8; » DOLTS; BLOOD
CIlSHa
a) 24 hr values after a single 4 g
dcse. Peak at 2 hr and then decline.
Considerable individual variation
1} levels at Sth day following tvice
B«althy 21-67 yr olds. «t 48-100 fcg
PEI1BCB; 1DOLTS: BLOOD: BLOOD PL1SIH;
IBtlGBSICS; JHTI-IBPLiBBlTOB! JCS8TS;
SBJLGtSTCS; JHTIfTBBTICS; D1TO
TBEBtPT: III VITBO aNlLTSIS; DBOGS
a) 0.5 hr after 30 ng/kg dose
t) 4 hr after 30 mq/ltq dose
O 4 and 16 hr after 250 ig/kg lose
0.5-6 yr olds
vciltlnq early symptom of overdose
CBILDBBE; LIVES DISE1SZS; BLOOD
Htsn: »B«tGESics: DRUGS; HEALTH
BIZlItDS

BEPEBEHCK
Carson, D.J.L.
Carson, B.D.
1977
Lancet 1 (8017) :894-897



Carson, D.J.L.
Carson, B.D.
1977
Lancet 1 (8017) : 894-897




Shlvely, C.a.
VO3O11, E.S.
1975
clinical Pharaaeology
and Therapeutics
18(4)1413-424


Callleai, p.
Callleni, 1.
illsln. p.
Benler, J.-c.
Therapie 34:81-87

Peterson. R.6.
Buaack, B.H.
1981
archives of Internal
Hedicine 141:390-394




-------
icetanilide. H'-hydroxy-  (8 CI)
Acetaiide, H-(H-hydrolTphenil) -  (9  CI)
103-90-2
CS-H9-S-02
BS 151. 16, 9t 169-170.5 C
                                                                                       (COHTIROED)
1
1
Tissns
»6»5
Urine
««96
Urine
1 9697
1 Urine
r
0618
Heine
«6M
flriae
EXPOSURE ROUTE m»ITTIC»l ITOHBSB
HETHOD 07 CiSSS
Ingestion HPLC 8
1
1
Tngestion IP 17
1

Tngestion


1
1
1
1
1

1
13
12
1
<
1
» 1
8JBGE
a) 7.«-27. 3 mg
b) 13. 0-25. » og
C) 26.5-171.0 ig
»2. 0-255.0 »g
1.30-122.00 •g/dl
137-425 ig/dl
a) 0.90-3. 89* of dose
b) 4.6-16. 8* of dose
0) 36.7-61.8' of dose
i) Not applicable
b) Dot applicable
;) not applicable
BE* I | GIIEB&L IHFOBB1TIOH I BEFE2EHCE
1 1
a) 16.5 mg
b) 17.6 >g
c) 81.7 mg
d> 170.8 ig
27.01 » oc - 36.29
•g/dl
1 1
1 a) Free, 6-3.5 hr after 11 dose I shively, C.I.
I b) Tree, 0-8 hr after IS dose 1 resell, E.S.
j c) Gluoironidate. 0-3.5 hr after IS I 1975
1 dose | clinical pharmacology
1 c) Glucutonidate. 0-8 hr after a* ! and Therapeutics
1 dose | 18 (»|: it 13-1121
1 CmulatiTe cicretion after 975-1,300 I
I «q. t
l i
I tcfore stqdy. t
1 1
I HUGS; 1ET1BCLISH; ADMITS; EIOOD I
1 ClftSHA |
1 1
1 |
1 Deitroorof oifphene poisoning | Carson, D.J.L.
1 fatalities. Alcohol and/or ether j Carson, E.D.
1 drags is tost cases. 1 1977
1 1 Lancet 1 ( 80 17) :89«-897
1 Ccroneus1 cases, ages 16-67 yr, I
1 northern Ireland |
1 1
1 Coia, death. (
1 scie, cerebral edeaa. |
1 I
I BEaGS: B100C: HEIST; SUICIDE; DHUG |
I IECISE: IBEUHD |
I 1
221.54 t or - 83.19
«g/dl
a) 2.43^ of dose
b) 12. 8« of Hose
c) »7.6% of dose
a) 0.06 ig
b) 0.58 ig
c) 1.03 ig
1 textrapropoiYphene poisoning | Carson, B.J.L.
I fatalities. Other drags found in r Carson, E.D.
•cst sablects. | 1977
1 lancet 1 (8017) :89«-897
Coroners1 cases, ages 16-67 jr. \
northern Ireland \
I
Coaa, death. |
Congestion and edeia of laogs. In I
sate, cerebral edeia. I
!
ESOGS; BLOOC; HEINE; SUICIDE; DBDS I
IEOSZ: I5ILJBD |
1
1
a) Onietabolized drug | LeTy, G.
b) acetaiinopben qlacuronide f Khanna* N.N.
c) acetiiinochen salfate I Soda. D.n.
It hr cuinlatire excretions after 12 1 Tsuzaki, o.
• g/itg ( stern, L.
f 1975
Healthy 2-3 day old, foil-ten I Pediatrics
infants. | 55(6) :818-825
1
ISOSS; OBI1I; SEHBOIISS; HESBOBM; I
StI I
1
a) AcetaBinophen \ Levy, G.
1:) acetaainophen glucaronide I Garrettson, L.K.
c) lcetaiino;hen salfate I Soda, D.n.
CuiQlative eicretlons 1st 1».75 hr of I 1975
life. Aether ingested 0.3 g I Pediatrics 55(6) :89S
phenacetin S.5 hr before delirery. t
t
Healthy nevbcrn |
1
osncs: MidBcts: osm-, -(ET»BCIISB; i
EBEGBiSCl; CUSE HISTORIES \
1
                                                                                                                                                                                           Ul

-------
Ice tic acid. {2,J-alchloro-0-(2-thienylcarbonyl) phenoxy) -
00180-00-9
C13-H8-C12-04-S
US 331.17
TISSUE
4700
Blood,
sera a



BIPOSOHS BOQTE
Zogestlon



avainicu
BETHOD
ec



BOUSES
OF C»SSS
6



BiBGE
_
a) 0.63-0.55 ng/nl
b) 2.35-H.68 ng/ul
e) 1.01-3. 6B ng/al
4) lot given
el Hot given
fj Sot given



•Ell
a) lot given
b) Rot given
c) Hot given
4) 0.34 • or - 0.17
(SI) og/nl
e) 0.55 « or - 1.20
(SB) cg/al
fl 2.83 * or - 0.59
(SB) aq/il



GB1EMI, IBFOBIUTIOH
e) Days 3 and 4
b) alcohol Mtabollte. days 2 and 4
c) Diaeld aetaboUt«, days 2 and 4
d) Dncnanged drag
e) llcohol Mtabolite
{) Dlacld netabollte
a)-e), 8 11, fasting saaple before
250 ig. d)-f), attar 5 hi
henoaialvsis on day 4
Inephcic 21-50 vr olds, on
beiodlalrsis >12 aoBtha, controlled
diet
lo effect o« else in serno gcic acid
after dialTSis
DIOOS; DBDS THEBIPT; ISROBIUTSIS:
DIOBETICS; 8IUBOLITES: KDBZT
tlSMSIS; StCOD SERDB; PEBB3TH»1IH
BBFZBEHCE
•array. T.«.
Brovn, S.
Dnbb. 3.9.
Bvang, B»t»
Stote, B.B.
1460
Clinical Tharnaeology
and Therapeutics
2T(5|s««6-«89



acetic acid,  («-
-------
  acetic tell. (a-{allTloxr)-3-cklacopae;irl|-  C*  CI)
  BeBzeawcetie acid.  3-calorc-«-(2-prope»jloirt- t» d)
  J2131-7»-»
  C11-«1t-Cl-03
  Rf 22C.CS,  IF M-93  C
TlSSVt
•783
Oriae

mosns JODTJ
lt«**U«»

ininicit
8C

imBJS
OF CaSSS
*) 32
14 W

met
a) lat glvea
b) «.8-»S.7 eg
I
mi
a) 50.4 a?
b) 4*. 2 eg

etinai ziFOBamoi
a] SOD «7 a* nspeuiai, overalgfct
faat
t) 1000 n la cipnle at aeiltlee
Caaalatin 2« be ezcnetiaaa,
EvalthT adelta
BtWSS; IBTX-lrFlftaflafOBI A€ZVTS:
trtiPTsnics: BICOD plasm; aeitt
IERCSTCZ
SeueUe, L.t.
Sa&dera, B.C.
Frieiaaa, 1.
Clielcal PkacMacolagr
aad Tk«np« Hot 9itea
f) rat ?i»a












6FIIBH ZrFOIIlTIOI

•1 2 kepatoaa petleats, dase a5 ao/cq
a
t| a aoa-kepataea patimta, dese
ac-as nj/sq a
c| 3 fcepatoia patients, deM 30 ao/«j
t
d| a noa-baratoat patieata, dase 30
ae/aa •
e) a hevataaa patieats, dase 15 ag/aq
a
f) 1 aaa-lwpata»a patleat, daee 14
0 «»J 25 kr, estiaated Dcoa qrapk*
Cata availatle far eetabolite.
*<-71 re aide >itk kepatoaaa aid
«tkec aeoplaua
»I6S; CBlgOlBSaaPT: CIBIBCSIS;
IIOFIISIS; EtOOB t>I»SHa: COBP1BITITE
•11101TIOIS; BRtBOIITZS; IDOITS
BIIISCTCI

Ckaa, It.S.
Cklebeeski, I.T.
Tong, 8.
Ckea, B.-S.G.
Croas, J.F.
Bateaaa, J.I.
1980
Cancer Beaeacch
«0:1263-126«










-------
tUiia*. 3-(B-(bls(2-cUero*tBrl1aBlao)p>eiirl-. I- <» CI)
1-PkeirlalailM, a-(W*(J-cbloro«tkTl.|aal«o)-  (9 CI)
1M~82~3
C13-V18-C12-I2-O2
HI 305.20, BP nppcox 177 C (decOBp)

»706
Blood.
plasaa






B70T
Blood,
plasaa.







»78B
TJEiBe









*709
Vrtae








ntosan sooti
Injection






Xagestlon







Injection










IneeetloB








tlliTTICaL
HETflOD
IndloaetCT






BPLC







BPLC










BFIC








mnns
or CUES







11


















11








IMSE
3.0-0. OSS «g/Bl






a) 0.07-0.63 ag/nl
b) 0.18-0.31 ag/nl







1.5-21.6^ «f dose










•I 2.»-21.»« of dose
b) S-1CX of do*e








•Ell
lot give*






a) 9.29 « or - 0.15
b) 0.31 * or - 0.11
•1/Bl






13.0 * or - S.a« of
Aoae









a) 10.9 » or - *.9f
of dose
b) 13.2 « or - 3.7*
of dose






et limit motiaiioi
ladlau. 0-6 hr attac 0.6 •«/»« IT.
Ilexponeitlal decay. Ertiaated fton
4Upk.
Cancer patl«Bts, aqa* M-70 IT, *t
a3— §6 kg
E«I«S; CIE10TBEI4PT; 9UEE: HOOD
illSBl: IEOPI1SBS; IISEISES:
IftMOLITES

a) 11 nblectc. nftar 0.6 ag/tq, aa
t) 3 aubleeta. nftec O.t B^Aa. a*
aclatlon
Vaake

29-70 yr old cancer patients, *t
«a-|* k«
tines: CMicnBiin: itomsBS; nooi
(iisii: it HI: conautiTE
tfiinitiois
24 kc accretion aft«r 0.6 a^/kq

caaeer patient*. a«w *«-70 it. at
as-a« k«

MOOS; cmoTBztini VIIIE; noon
CI1SI1; ISOH1SBS! DISMISS ;
tKlBOtlTES



a) 11 aab-|«cts. after 0.6 ag/tq as
tablets
b) 3 a abject i, after 0.6 sa/k« as
aelitlon
2«-ne exccetioBs
29-70 TE old cucec patienta. «t
««-«< kg

DfOSSt CBnOTIEBMT: KOPLaSBS: B100B
msti: mm: COI*BUTI«E
ZTllVHIOVS
BETSIEICI
llberts. B.S.
Chang, S.T.
Cken. B.-S.O.
Evans, T.I.
rarner, t.U
Ilsnelatein. K.
Cross, J.r.

Cliaeal Paarucolofr
and Tberapevtlcs
26O):73-M
tlberts. b.S.
Cku?. S.T.
Chen, H.-S.B.
CTBBS, l.l.
Boon, T.E.
1979
Clinical Phacnacologj
and Thecapaatics
2t(6(:7J7-7«5


tlberts. D.S.
Ghana, S.T.
Cken, B.-S.5.
BOOB, I.E.
Evans, l.i.
ram*r, B.t.
Blanelstel*. I.
Gross, 3.1,
1979
Clincal Pnarnacology
and Therapeutics
26(1): 73-10
alberts, b.S.
Chang, S.T,
C&ea, f.-S.S.
I rans. I.L.
BOOB, T.I.
Clinics 1 CharMcologr
and Therapeutics
26(6):737-TI5




-------
  alDna-f t-n-Olo-I-isoiDdolinjDphenrllpropioaic acid (go postings in CREILXR) .
TISSIJB
(710
aiooa.
plasea










IIPOSUOT BOOTS
Ingestion









I
i Mi-men,
SET HOD
GC










BWWSB
OF CiSIS
1










MUGS
a) 1.0-7.5 ng/al
b) 6.0-0.7 ag/«l










Hill
a) lot applicable
b) Hat applicable










eziiMi, moBUTiai
a) d-enantiover* 0.5 and 1.5 lie
after 200 mg cacaiic aiKtare. Final
leatnnaent, 1.8 ug/il at 10 hr
H 1-enantloier. 1 ud 10 hr after
200 • as btoiida. 61/iaf

iTastkenic patieot. U.S.

MOGS; BLOOD 9USU; SSiSDSIKIT
8ITBODS: OflTID KIISD01




EHFESIBCB
DlTison, S.C.
Ffman, f.
Prentis, S.I.
Dehqhan. 1.
Chan, K.
1980
Methods and Findings IB
experimental and
Clinical Pharmacology
* <2) -.77-62
                                                                                                                                                                                           Ui
liiontai,  (o-bro«obeniTl)sth7ldi«etbfl-, p-tolaenesilfonate  (8 CI]
I«neB«etkaraainin«, 2-bro»o-Ii-et!>Tl-».1l-4i«etiTl-, salt »itb a-Mtkilbenienes»lloi.lc  acid  11:1)  [9 CI>
«1-75-6
C 11-B17-Br-».C7-ll7-03-S
«« «!».», HP approi 98 C
IISSOE
•712
BlOOl,
scna










EIPOSDE? SOOTF
Tnjection
laoestioa











illtlTlCil
KETIOB
SC












IDBBn
OF ClStS
10












B1WGE
a| 38-1*3 «?/«i
b| 1134-2«36 nq/al











I»1W
a) 76 ng/al
b) 1896 oq/ll











GEiieii T»ro«ai7io»
•) Feat after 5 «o/*g, oral
t| Peak after 30 «ln IT. 5 i^Ag

lealthT. 20-«7 rr olis, Michigan

iniietTr fleshing, eiclteaent.
increased blcod pressare and heart
rate, liTTio«ss, nasal congestion.
transient headache aid nausea in
EC a*.
(ICBIGIH; 1DDLTS; BLOOD SEIOfl; IT5I1E;
IITTHTPnTIlSITf 16ERS; DHOGS;
CCIPlBlTItl ETJUOlflOKS
BBFEREBCE
Inlerson, J.L.
Patterson. 1.
(aaner. J.G.
Stevart, J. B.
Beha, n.l.
Incchesi, B.3.
19BO
Clinical Fnamacolog7
•ad Therapeutics
23(«):««8-«7»



                                                                                     (HIT P1GE)

-------
insoiinn, ro»l>e«nietnTl4lBethTl-. p-tolaenesnllonate (6 CI)
BeareneaetlLanaBlnivB, 2-broao-*-etn7l-t,*-dinetBTl-. salt with 1-neUiTlbanzeiwsalfonic add (1:1)  <9 CI)
61-75-8
C11-H1T-Br-».CT-HT-03-S
n »1».a. IF appro* »8 C
                                                                                      (COtTMMDJ
TISSSS

• 713
Blood
aerui












»7ta
UriM











nposuas ROJII

Inlection
Tngastioo













Zn faction
Inaestion











IHITTIC11
HRHCD
ec-sc














EC












WDHBIB 1
or cisss
aj 6
M 7













10












I USE

a] 2.5-0. 08 og/sl
b) 72-»61 ag/ll












..
a) 0.3-0.9* DC dosa
b) 0.1-P.2* of dose











BSII

a) lot applicable
b) 1»« tg/ml













a) lot giYen
b) lot glTBB











GIKBIL xnOlMIIOI

») Initial muuaMat av4 2n hi
altar 5 >g/k tosTlate

Ociiae patients, «*-77 ji all, oral
thecapr after 3-7 days ol IT thicapy.

Tulabla, aostlT postural.
bytoteaslon litb oral tkarapy.
ItDlTS: CilBIOTISCTUlB BISHSSS;
t!IST DISUSIS; BLOOD SIBDB;
iiTiiBEaiianjc lerats: DBOG TSBBIPI:
CllSntKHR IREOOS
a) Beak a IMC 3D ala IT. S aa/kg
t) P«at aftet S t-ci/k-?. oral

HtaltM. 279



                                                                                                                                                                                            OJ
 InillM, a.a'-salfonTlil-  (8 CI)
 Mni«Mailn«. «.*>-siilfonTl1>ls-  (9 CI)
 SO-08-0
 C12-H»i-»2-02-S
 H 2»».30, »P !75-t7« C
TISSDt
•715
31ool,
scrat

















EXCOStnt! BODtE
In«eatlon



















tlUTTICU
IWHOB
riioroaetty



















gOSBIB
OF C1SES
6



















1»GI
a) 2.5-0.1 19/1
b) 3,0-0.02 »g/\
cf 2.0-0.07 •?/!
fl) Z.S-0.03 «g/l
a) 15-0.5 mg/l
I) 10-0.34 *j/l














Kll
j.
a) vot giTeo
b> Tot gi¥en
el Tot gli«n
}) lot giren
e) lot giten
I) lot gireo














CtltUI. HFOBHITIOI
al Dapaan* dose 100 ag/day, 5 dars

-------
  iBiliae, «,«I-sslfo«Tl4i-  (> CII
  Beimteaslae, »,a'-salfonTlbl»-  (9 CI)
  (0-08-0
  CTJ-»12-»2-02-S
  If 2*8.30, IP 17S-17S C
nssn
»7M
Or IBS
cxposm IODTB
laeestios
aiaimcii
•craoi)
rlioroeetry
•HUB
OF C1SIS
«
Hies
i) lot given
b) lot given
e| lot gina
d) lot given
*) tot applicable
f) (at applicable
szi» i GintiL iirotnnoi
I
i
•) 16.C » or - 1.1* | •) tavsoae. «o*e 199 eg/daT, S dar*
of Aw* | (ttam 1)
b) 9.9 » or - O.SS of I 1} after 118 9 activated charcoal
lorn | 10-58 he after last dapsoae dose
e) 6.3 « or - O.M of | (rkase 2)
too* | c) 9oaa>»tTiaapaoa«, phaaa 1
i) *.2 * or - t.ZX of | l| amote*tTld*f>s-*-clil0ro-2-((2-facaaylMt)iTl)"li'O>- (9 CT)

C12-»f1-cl-»2-O5-J
9> 330.77, BP 20C C
CO
Ui
oo
IIJSOB
«7I7
Blood,
plasaa
nrlae

Exrosras torn*
Injeetloa
laJeetioB

8TTIOD
DC
SC-JC

JOBBBS
or cuss
c
16

1IICB
a) 750-604 nq/al
b) 7SO-tS8» ng/al
a) 22. « 0-73 .4*. of lose
b) 3.]-ao.*« of dose
c) 0.13-3.92* of lose
inn
BUI i GEKUI urotnnoi
1
i
a) lot gives I a] Initial acasareaent aid 2.5-3 fcr
b) Hot given I after IT kolas of TO ag, then
1 coBtlneons lafnsioa of 8 ag/hr
1 b) Initial eeasareaeat and several hr
I attar 1 gs crobexcid IT 2.5-3 hr
1 after start of iufnsioa
I !«se valves tstlwted fro* gnph.
1 BtalthT 22-2t rt olds, welqkinq 7« «
t or - 8 kg, fasted before dose.
1
1 sacked diuresis
1
I noes; SVZDEI; TUIIE; BLOOD 111911;
1 BlntmCS; BIOS IREMCTIOI; lOfllTS
1
a) 56. 0* of dose | a) Oichaiged faroaealda
b) 10.784 of dose I t) Contagated fvroseaide
c) 1.88* of doae | c) Icid aetabolite
aadlans 1 21-hr caaelatlv* ezeretions after
1 2C-UO «g farosuid* Iseaa dose *
1 «7.2» *gl.
1
1 2t-88 Tr olds «ith ante pvlaoaarT
1 edesa, «t »*.»-100 kg, sose OB other
1 liags, soae with acote avocardlal
1 itfacction.
1
1 tunes; atTiBcusa: BCTIBOLITIS;
1 CIIIOI; DI01RICS: tM5TOE»n
1 EitMDS: BBIIT oiSBisss: aim:
1 ccapitHTUt EuimTiois: IDUITS; MUG
I Tinivr
(
•a6B|
fiBTSBERCX
Odllad, B.
Beernaan, S,
1980
Clinical pharaacology
and Thenpentlcs
27(«)s78S-790
Fetei, J.
Sltar, D.S.
Ogilvie, (.1.
1979
Drag Retabolisa aid
Disposition
7(«J:383-38T


-------
littmllle acid, a-chloro-B-farfnryl-S-selfaeojl- |« CI)
ieaiole acta. *-faeiaonlfoiyl)-*-chloro-2-((2-feraaylnethyl)aBiao)- (9
5«-31-9
C12-B11-C1-BS-OS-S
81 330.77, 8P 20C C
CI)
tlSSBl
•719
Brine



nposviB ton*
Injection



IMITTICH.
BSTHOD
ec



BOBBES
or cisss
6



1UGI
a) 2.86-3.21 ng/30 ill
b) 1.75-1.25 if/30 (in



mi
*) not given
b) lot given.


i
Gzitaii iiroiitnoi
.
i) Initial Btasicmeat and 2.9-3 hr
•ft«t IT bolus of 10 ng, then
contlnnons infnsion of 8 ng/hr
b) Initial aaanreaeat and several ir
after 1 qm probenecia IT 2.5-3 he
aftur start of lifasloB
Sea* Tala«« catlaat*! £COB qraph.
I«althT 22-21 re <>14», nlgUaq T« *
or - B *a, fasted before flos*.
sar*«4 ainreals
Dines; sinzi; nr»; BLOOD ntan;
D MIMICS: DSOS mnicnoi: IBOITS
nnmci
oaiiaa, B.
Beermii, B.
1980
Clinical Phanacology
ai8 Tk*rap««tlcs
27(«)s7M-790



            (• CI)
3H-rrr»»ol-3-on«, 1>2-ai>raro-1.5-aiMthrl-2-pbmrl-  (9 CD
$0-80-0
C11-B12-12-0
81 188.22.  RP 111-113 C
1ISS8S
«720
Blool.
plasaa












»721
Bloo4,
plBSBB







»722
Saliva








Mfosoits toon
Isolation
'












lB4*StiOB









lagastioB









•IlLTIICaL
1OTBOD
HI












OC









ec







,

IOBBBS
or cisss
10












11









11







.

Hies
a) tot given
b| Bat gl*an
c) lot giT«B
A) Bot giT«B
•) BOt giT«B
f) lot given











11.5-26.0 ng/Bl









12.5-29 ag/il








(BUT
n*i
a) 2.21 ag/al
b) 2.18 «g/al
O 1.M »9/sl
4) 1. M ag/il
e) 0.*5 ng/al
f) 0.35 ag/Bl











Bot given









Bot given








MG1)
6SBI1U IITOIBMIOI
a) Control ai«t - 3 hr
r) trnssels cpoBte «»4 catbage aiat -
3 nr
c) Coatrol diet - 9 hr
i) Erv*sels tpronts a*4 cabbage 41et
- 9 hr
e) Coatrol diet - 30 hr
f) Brassels (pouts «n4 catbage aiet -
30 hr
1) Dose »as 1.8 nq/kg
9-30 hr valves sigalficantly
aiffereat
21-32 vt old*. »t 50-79 Itg.
icnaaokers, fasted before and after
dose.
mass; gins; BIOOB PLISBI;
inuoinis: coBPUtnvx imainoBs
Peaks. 3 hr afer 18 ngA?
Talne* hiqhlr correlated vlth saliva
valves. BoBoezponeatial decline.
Istlnated froB graphs.

Eaalthr adnlts. aqes 22-30 rr.

ItOHS: BtOOD PLIS81; SUITt;
iiiicesics: jiTiPTsmcs: Dives:
CClMBlllrj CTIlIITIOfS
Peaks, 3 hr after 18 ag/kg.
BOBoexponential dec 1 lie. Zstlaated
fres graphs.

(ealthv adalts. aqes 22-30 vr.

ltD»s; BIOOC PltSITl; S11IT1;
liaiGBSICS; anipnZTICS; MUGS;
CCTtlBITITS Et»LO»TIO5S

KniEBCB 1
I
PantocV, B.J.
Pantack. C.B.
Garland, B.a.
Bll, B.H.
Batten berg. 1.1.
anderion, K.I.
Kappas, 1.
Conner. »-H-
1979
Clinical Pharaacology
and Therapeutics
25(1): 88-95





Vesell, E.s.
Passananti. G.T.
Glenvrlght. P. ».
Dvorehik. B.H.
1975
Cllaleal Pharaaeologf
and Therapeutics
18 (3) -.259-272


Vesell. Z.S.
Passananti, G.T.
Glenniqht, P.I.
Dvorehik, B.H.
1975
Clinical Pharaacologv
and Therapeatics
18(3): 259-272


                                                                                                                                                                                         Ol
                                                                                                                                                                                         VO

-------
 latipyriie  (8 CX)
 3B-Pyra*ol-3-one. 1.2-dih7dro-1,S-dinetkTl-2-pkeiiyl- (9 Cl)
 60-80-0
 cn-ai2-»2-o
 HI 188.22, HP 111-113 C
                                                                                       (COITIIOED)
TISSUE
«723
Brine














EIPOSI1BT ROUTE
Tngestion















lIUlTTICm
HETHOD
TIC
<3C














•DHBS1I
OF C»SES
1















H1ISE
a) lot applicable
b) lot applicable
c) lot applicable













•Ell
at 33* of dose
b) 17* of dose
c) 17* of dose













GEMIU IIFO1BITI01
i) la •-kydrexrantierrine
t) Is 3-aydroxyMtliylantlpyrine
c) Is lorantipyrine
0-50 ar cneelatlre excretion after 1
g

70 kg, vkite asle pkenotyped as "poor
•ataboliier" according to capacity to
t-kydroxylat* debrisoguine aid
sparteine.
DSDSS; ggttBOllSn: gSTUOlXTES;
OII«I: COSP151TITE ET»10»TIO»S:
SfDITITBS; BTPBOTICS; iBTIPIBETICS;
IITIHT?WTE»SIYE 16MTS;
IITHFBBIIHBIC 1GKITS
1
BEFZRBRCI
Inaba, T.
Of ton, 5.T.
Kalov, V*
1980
Clinical Pkariacologr
and Therapeatics
27t«):5»7-5»9









IBtlpyTlae. »-(di«ethTlaaino)-  (8 CI)
3B-Prrazol-3-one, H-5-aiaet]iTl-2-phaa7l-  (9  CD
58-1S-1
C13-B17-113-0
HI 231.2». BP 107-109 C
TISSOB
«72»
Blood,
plasia
»T25
eiood.
plasia
•726
Saliva
3XPOSm>I FOOT
lagestioo
Ingest ioa
laqestlon
KlXTTICItl
MTHOB
GC
oc
sc
iOHBSS
OF C1SES
12
«
11
FJKGB
». 5-6. 2 ng/Bl
a) lot gireo
b) lot glTeo
1.7-7.6 og/»l
mil | GEtiui iiroiflinoi
I
i
Hot glrea | 3 be after 9 Bg/kg. 3stiiated froa
| gtapfc,
| KaltkT adults, ages 22-30 jl.
| 1 EDITS; BIOOD PllSHl! SUITl;
| H»ieiSICS: MTIPTBETICS; BBOGS;
| CC'PIFITITE irilffHtORS
|
a) 8.01 » or • 2.52 1 a) Dose, 2 ig/lcg at 8 >.H. aftec
•g/1 kr | 12-hr fast
b) 7.96 * or - 1.13 I b) Dose, 2 igAl at 8 P.B. after
•g/1 kr j itnal aeal at 5 P. a.
I liea under tbe carve for free * bound
I drug
| ffcalthr 22-31 yr olds, wt 59-85 kg
| PHKSTLTiKU: »DOLTS; BIOOD FllSlil;
I IHIGtSICS; IITIPIKBTICS: DHOGS;
I CCIPIRITITE miomofs: DIRS
1
1
Hot given | 3 hr after 9 eg/kg. Honoexpoaential
| decline. Rstieated fron grapk.
I ecaltkr adults, ages 22-30 rr.
1
I It HITS; BIOOD PUSH; SUITl:
I IHlGtSICS; HTIPIFETICS: BFOTS;
| CC8PI1ATITJ mlOlTIOIS
BKFEBEBCE
resell, l.S.
Passanantl, G. T.
GleaRlght. P. a.
Drorchilt, B.B.
1975
clinical Pkariaeologr
and Therapautics
18 (3>t 259-272
Sbirelj, C.I.
sinons, B.J.
Passaaant, O.T.
DTorekik, B.F.
Tesell. t.S.
1981
Clinical Pbaraacology
and Tkerapentics
29{1):«5-73
Vesell, t.S.
Passanantl, G.T.
Glenvrigkt, P.I.
DTorekik, B.H.
1975
Clinical Pkanacology
and Tkerapeatics
18 (3) J 259-272

-------
Barbitaclc acid. 5-(1-eyclohe«en-1-Tl)-1,5-dl»ethvl- (6 CI>  nil)
2,l.«(1».3H,5in-PTrlsidinatrione, 5-(1-evclahex«n-1-yll-1.S-diMthrl-  (9  CI)
C 12-B1S-I2-03
•I 238.26, SP 1*5-1*7 C
1ISS1!

*727
Blood,
plasaa







«728
urine









txrosoif soon

Injection








.
Infection










II1LTTIC1L
WTHOD
GC









GC










IOBBIS
O? C15BS
1









at 6
b> 11









BUS!
_
a) 4.3-12.8 »g/l
b) 12.8-2.0 ig/1








a) lot given
b) tot given
cj lot given
d) lot given







mi

a) lot applicable
b) lot applicable








a) 02.3 * or - 13.6 *
of dose
b) 12.6 » or - «.1 «
of dose
O 0.31 t or - 0.13 *
of dose
d) 0.33 » or - 0.2« t
of dose




GEI1B1L tirOIBlTIOl

al 5-60 a la infusion
D) 0-720 aia post-lafasioa
Cose, 556. 2 ig (7.32 ng/tql as sooin
salt. Biezponentlal decay.

60 vr old hepatitis patient.

DSTISS: BCTaBCLISB; IDOITS;
CCHP«B1TIVE HVIIOITIOSS: OBIITi BLOOD
PUSItl: Llt