WATER POLLUTION CONTROL RESEARCH SERIES
18050DOL 03/70
   BACTERICIDAL EFFECTS OF ALGAE
        ON ENTERIC ORGANISMS
U.S. DEPARTMENT OF THE INTERIOR • FEDERAL WATER QUALITY ADMINISTRATION

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        WATER POLLUTION CONTROL RESEARCH SERIES

The Water Pollution Control Research Reports describe
the results and progress in the control and abatement
of pollution in our Nation's waters.  They provide a
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Reports should be directed to the Head, Projects Reports
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On Cover:

      Sunfish             Lepomis gibbosus

      Bullfrog            Rana catesbeiana

      Spotted salamander  Ambystoma maculatum


Drawings By:

                Alston Badger
         Bears Bluff Field Station
National Marine Water Quality Laboratory

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         BACTERICIDAL EFFECTS  OF ALGAE

             ON ENTERIC OBGAJHSMS
      Ernst M. Davis, Assistant Professor
         Earnest F. Gloyna, Professor

    CENTER FOR RESEARCH IN WATER RESOURCES
Environmental Health Engineering Research Laboratory
       Civil Engineering Department
     The University of Texas at Austin
                   for the

      FEDERAL WATER QUALITY ADMINISTRATION

          DEPARTMENT OF THE INTERIOR
               Program #18050 DOL
                  March, 1970

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                         ACKNOWLEDGMENTS

    The financial assistance of the Federal Water Pollution Control
Administration has made this investigation possible.
    Appreciation is extended to Dr. R. K. Guthrie,  formerly of North
Texas State University for bacteria cultures and advice; also to C. Clifton,
J.  H. Bandas, D. Trigg, C. J. Rogers, G. Sparks, A.Gravel, R.  Morales,
and T. Mercer, all students at The University of Texas at Austin, Austin,
Texa s .
                                   111

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                              ABSTRACT

    A series of experiments involving the effects of blue-green and green
algae on the dieoff rates of selected bacteria have been conducted.  The
algae were axenic cultures of Anabaena cylindrica, Anacystis nidulans ,
Gloeocapsa alpicola,  Oscillatoria chalybia, O. formosa, Phormidium
faveolarum, Ankistrodesmus braunii, Chlorella pyrenoidosa,  C .  vulgaris,
and Scenedesmus obliquus.   Cultures of enteric bacteria species (Alcali-
genes faecalis, Enterobacter aerogenes, Escherichia coli,  Proteus vulgaris,
Pseudomonas aeruginosa, and Serratia marcescens) were added to the
axenic algal cultures  during different periods of the  algal life cycles.
    Cultures of the normal blue-green contaminants were exposed to the
enterics  to determine  antagonistic effects toward the enterics. Filtrate
from actively growing algae was exposed to cultures of enterics to determine
whether any antibiotic compounds were  imparted to the medium during lag
phase growth of algae.  To determine aftergrowth of the enteric species,
the duration of the tests was extended to about 90 days. Mixed cultures
of green  and blue-green algae were exposed to both single species of
enteric bacteria and mixed cultures.  The results indicated that mixed
algal cultures cause a greater dieoff among the enteric bacteria than do
individual species of  algae.  The dieoff characteristics of pathogenic
species, namely, Salmonella typhosa, S. paratyphi, Shigella dysenteriae,
S_._ paradysenteriae, and Vibrio comma were also determined.
    The  pathogenic species did not survive as long as the enteric test
species under similar test conditions.  Virtually no aftergrowth was detected
on the part of the pathogens .

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                            CONCLUSIONS

    The following conclusions are derived from the results of this investi-
gation.
       1.  Dieoff coefficients for individual species of enteric bacteria
in the presence of axenic cultures of algae  were comparatively  low, the
majority of the coefficients being near or less than -0.1 per day.  Chlorella
pyrenoidosa and Chlorella vulgaris caused the highest dieoff coefficients
among enteric bacteria.  Chlorella spp.  were substantially more effective
than Ankistrodesmus braunii or Scenedesmus obliquus in effecting acceler-
ated dieoff S .
       2 .  Mixed cultures of either the blue-green or green algae caused
significantly higher dieoff coefficients among the enteric test bacteria as
well as the pathogenic bacteria tested.  The majority of the coefficients
were between -0.1 and -0.2 per day.
       3.  Effects exhibited by enteric bacteria on the growth of individual
algal species depended on the algal species in question.  Constant patterns
of increased or decreased algal growth coefficients were uncommon.  In
the majority of algae  species, a slight inhibition of the overall growth
potential of the algae was observed.
       4.  Dieoff of enteric bacteria was more  rapid under aerobic con-
ditions than anaerobic conditions.
       5.  Aftergrowth of Escherichia coli, Pseudomonas aeruginosa,
and Serratia marcescens occurred in axenic blue-green algal cultures as
well as in waste stabilization pond  effluent.  Alcaligenes faecalis,
Enterobacter aerogenes , Proteus vulgaris, Vibrio comma, Salmonella typhosa,
Salmonella paratyphi, Shigella paradysenteriae exhibited no aftergrowth
potential  under similar conditions.  Serratia and Pseudomonas exhibited
a greater  aftergrowth potential than  did E. coli.

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       6.  As the algal species reached their stationary and/or log death-
growth phase in the laboratory, quantities of organic carbon were released
to the medium; up to 200 mg/1 was not uncommon.  Prolonged survival
periods and/or aftergrowth by some of the enteric bacteria were attributed
to this nutrient source.
       7.  Consistent dieoff effects on enteric bacteria  in laboratory and
field waste stabilization ponds were achieved only after appropriate periods
of acclimitization of the pond microcosms.  Those periods were observed
to be as long as 30 days, or more in some instances.  Dieoff coefficients
for early stages in pond treatment units were higher than those obtained
for secondary stages such as maturation ponds.  Higher coliform concentra-
tions and increased competition for nutrient sources in early treatment
sequences  were attributed to that rapid dieoff.
       8.  Compared to axenic algal  culture experiments and laboratory
scale ponds, the most rapid reduction in enteric bacteria occurred in the
waste stabilization ponds located in the field.
       9.  In laboratory ponds, E. coli exhibited a greater resistance to
dieoff than did Pseudomonas aeruginosa or Serratia marcescens; but in the
field ponds, E. coli exhibited the highest rate of dieoff of any enteric
bacterial species tested.
      10.  Occasional increases in concentrations of  Pseudomonas and
Serratia were noted in laboratory and  field ponds. Short-circuiting was not
considered to be the causative factor, but an association of these two
genera and other enteric bacteria with clumps of algae might have been
responsible for this increase.  Pseudomonas spp. exhibited increases
in numbers when the total algal concentrations were lowest in both the labo-
ratory and field ponds.
      11.  Total coliform bacteria counts  decreased significantly during
periods when the pond phytoplankton  population was highest,  and vice
versa.
      12.   The vast majority of bacteria  in all pond effluents were of
the group of bacteria referred to as the chromagens; included in the group
are Flaveobacterium and Brevibacterium.  Cultures of these two separate
                              vi

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genera were shown to exert marked antagonistic effects on enteric bacteria
when together in culture.  Flaveobacterium was more antagonistic to enteric
bacterial species than Brevibacterium.
      13.  On several occasions  extended periods of incubation were
necessary to produce any recordable growth of Pseudomonas spp.  from
waste stabilization pond samples using either nutrient, trypticase soy,  or
Endo agar plates.  Special consideration should be given this factor when
total or enteric counts are made from wastewater environments.
                                  vii

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                        TABLE OF CONTENTS


                                                            PAGE

ACKNOWLEDGMENTS                                           iii

ABSTRACT                                                      iv

CONCLUSIONS                                                 v
TABLE OF CONTENTS                                          viii

LIST OF TABLES                                                 **

LIST OF FIGURES                                                x

CHAPTER
    1     INTRODUCTION                                       1
              Bacterial Characteristics                          1
              Review of Literature                               3

    2     MATERIALS AND METHODS                             9
              Algal and  Bacterial Cultures                        9
              Laboratory Investigation Series Identification        13
              Laboratory Data Analyses Methods                  15
              Laboratory and Field Waste Stabilization Pond
                Studies                                        16

    3     LABORATORY CULTURE DIEOFF EXPERIMENTS             17
              Enteric Bacteria Dieoff Studies                     18
              Pathogenic Bacteria Dieoff Studies                  25
              Aftergrowth Potential Measurements                 25
              Organic Carbon Production by Algae                 27

    4     LABORATORY AND FIELD WASTE STABILIZATION
            POND STUDIES                                     30
              Laboratory Waste Stabilization Pond Studies         30
              Field Waste Stabilization Pond Studies              44

BIBLIOGRAPHY                                                 54
APPENDIX A:  STATISTICS OF ALL LABORATORY AXENIC              59
   CULTURE STUDIES
APPENDIX B:  BACTERIOLOGICAL DATA FROM LABORATORY
   AND FIELD WASTE STABILIZATION POND STUDIES                97

APPENDIX C:   PROGRAM BETA FORMAT                           126
                                 vm

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                            LIST OF TABLES

TABLE                                                          PAGE
 2-1   Composition of Algal Culture Medium                      10
 2-2   Element Concentrations in Algal Culture Medium           11
 2-3   Algae and Bacteria  Test Species                           12
 3-1   Dieoff Coefficients for Series Utilizing Axenic             19
         Algal Cultures and Enteric Bacteria
 3-2   Dieoff Coefficients for Series Utilizing Pathogenic         26
         Bacterial Species
 3-3   Aftergrowth Characteristics of Enteric Bacterial            28
         Species with Single Species of Algae (Series  I)
 3-4   Total Carbon and Total Organic Carbon Content of         29
         Biomass After Ninety Days (Series BG-I, G-I,
          BG-VIII, and G-VIII,  in mg/1)
 4-1   Bacteria Inoculated Into Selected Stations In Laboratory    33
         Waste Stabilization Ponds
 4-2   Dieoff Coefficients of Inoculated Bacteria in Laboratory    34
         Scale Waste Stabilization Ponds
 4-3   Phytoplankton Found in Laboratory  Waste Stabilization     36
         Ponds
 4-4   Total Phytoplankton Concentrations Found In Laboratory    37
         Waste Stabilization Ponds
 4-5   Bacteria Inoculated Into Selected Stations of Waste        46
         Stabilization Ponds
 4-6   Phytoplankton Found in Waste Stabilization Ponds         51
 4-7   Phytoplankton Concentrations Foundin Waste Stabiliza-    52
         tion Ponds
A-l through A-72
       Appendix A: Statistics of All Laboratory Axenic            59
         Culture Studies
B-l through B-28
       Appendix B: Bacteriological Data from Laboratory         97
         and Field Waste Stabilization  Pond Studies
                                   IX

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                           LIST OF FIGURES

FIGURE                                                        £££J
  4-1     Schematic of Laboratory Ponds                          31
  4-2     Total Bacteria, Laboratory Ponds                       38
  4-3     Total Coliform, Laboratory Ponds                       39
  4-4     £_._ coli,  Laboratory Ponds                              40
  4-5     Phy to plank ton Densities in Laboratory Ponds            41
  4-6     Schematic of Waste Stabilization Ponds                 45
  4-7     Total Bacteria in Waste Stabilization Ponds             48
  4-8     Total Coliform in Waste Stabilization Ponds             49
  4-9     Phytoplankton Densities in Waste Stabilization Ponds   50
                                   x

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                              CHAPTER 1
                            INTRODUCTION

    An important reason for the treatment of domestic wastewaters is the
reduction or elimination of the enteric bacteria from these wastewaters;
in this connection, waste stabilization ponds have been used successfully.
In established ponds the most obvious population consists of various species
of algae  as evidenced  by their pronounced color.  These algae, under
proper pond design, can produce the greater percentage of required dissolved
oxygen and can  interact with the entire biological community.  As yet,
however, the specific  role that algae play in the overall reduction of enteric
bacteria  in waste stabilization pond systems has not been firmly established.
     The  purpose of this investigation was to determine the degree of
toxicity  exerted by typical species  of blue-green and green algae on
representative bacteria found in wastewaters.  The  scope of this investiga-
tion included:  (a)  long-term  studies involving selected species of algae,
coliform bacteria,  and pathogenic bacteria; (b)  bactericidal and bacteri-
static effects; (c) algal culture filtrate effects on bacteria test species;
(d) aftergrowth capabilities of test bacteria by extension of study periods;
and (e) enteric bacteria dieoff investigations in both laboratory waste
 stabilization ponds and field ponds having different design characteristics.
 Bacterial Characteristics
     A brief description of some of the important characteristics of the
 bacteria studied in this investigation is appropriate in order that their
 complexity and the significance of  their reduction in wastewaters can be
 fully appreciated. Coliform  bacteria are, by definition and  description,
 inclusive of all aerobic and facultative anaerobic,  gram-negative, nonspore-
 forming  rod shaped bacteria which are capable of fermenting lactose with
 gas formation within forty-eight hours at a temperature of 35 degrees

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Centrigrade (27).  They have been variously named the _B.. coli group and
the coli-aerogenes group in past years with no change in the specifications.
By this definition, therefore,  only part of the bacterial flora inhabiting the
gastrointestinal tract of animals are coliforms.  The total number of genera
which are capable of living in those conditions is largely unknown. Invari-
ably, species and varieties of Escherichia,  Streptococcus , Clostridium,
Aerobacter (renamed Enterobacter), Paracolobactrum, Salmonella ,  Shigella,
Proteus,  Pseudomonas, Alcaligenes, Serratia, and Bacteriodes are among
those found.   In this sense any species which has the capability to sur-
vive and multiply in any intestinal tract could be called an enteric bacterium
Taxonomically, the enteric bacteria follow this classification (26):
       Order Eubacteriales
           Family Enterobacteriacede
              Genus Escherichia
              Genus Aerobacter
              Genus Klebsiella
              Genus Paracolobactrum
              Genus Alginobacter
             Genus Erwinia
             Genus Serratia
              Genus Proteus
              Genus Salmonella
              Genus Shigella
Other genera which are found routinely in domestic wastewaters have  the
following classification:
       Order Eubacteriales
           Family Achromobacteraceae
             Genus Alcaligenes
       Order Pseudomonadales
           Family Pseudomonadaceae
             Genus F*seudomonas
To assume that all of the species of the genera listed in the above classi-
fications are nonpathogenic would be  erroneous.  Several species in the
Family Enterobacteriaceae, for example, have been known to be pathogenic
to man, producing various intestinal diseases and septicemic infections.
For this reason alone their elimination from wastewaters is of utmost

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importance, Alcaligenes faecalis has been isolated from infections of
bacteremias, gall bladder infections, eye infections, and has frequently
been incriminated in cases of enteritis .  Species of Pseudomonas, by the
same token, are frequently encountered in eye and  ear infections as well as
urinary tract infections (26).  This genus  is universally treated with a great
deal of respect, especially in facilities in which burn patients are housed.
A septicemia caused by Pseudomonas may occur as frequently as staphy-
lococcal septicemia in severely burned patients and in persons who have
leukemia.  The outcome is usually fatal.
     The genus Vibrio, which has several  nonpathogenic water-borne  species,
is also  found in the Family Pseudomonadaceae.  Most dangerous of the
species are Vibrio comma and Vibrio El tor which are the causative  agents
of the well-known Asiatic cholera.
Review of Literature
     The mechanism by which populations of undesirable bacteria are reduced
in numbers has been the subject of many  investigations.  In waste treat-
ment facilities the  bacterial dieoff is affected by several factors.  In lakes,
reservoirs, impoundments,  and  streams the bacterial dieoff may be assumed
to be similar insofar as these factors are concerned.  The principal difference
between the aquatic environments is one  of bacterial concentration.  Some
of the factors which undoubtedly play an  important part in the bacterial
 dieoff mechanism are sunlight,  pH changes, changes  in oxygen tension,
 predation by other  organisms such as rotifers,  changes in organic content
 of the water,  temperature, and antagonistic  effects of other bacterial
 species and other faunistic species such as fungi  and algae.  Gravel,
 et al. (2)  found temperature, pH, and dissolved oxygen concentration to
 be important, in that order,  in dieoff rates of reservoir coliforms.  Gameson
 and Saxon (3) attributed the dieoff primarily to sunlight effects.
     Bacteria  must have  certain quantities of organic carbon present for
 their survival or multiplication.  Ward and Moyer (14) reported that organics
 excreted by algae  during growth could serve as bacterial nutrient sources.
 This source of carbon may reach appreciable concentration levels.  Hellebust
 (13) reported  that some phytoplankton are capable  of excreting up to 25

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percent of their photoassimilated carbon during their log growth phase.
Therefore, when large populations  of algae are present, adequate supplies
of carbon should be present for the survival of some of the coliform bac-
teria.  Data presented by McGrew and Mallette (10) stated that some bac-
teria of intestinal origin, including Escherichia coli, could survive and
even multiply at concentration levels  of glucose less than 5 micrograms
per milliliter.
    The literature contains various reports of interactions between coli-
form s and other faunistic species such as algae.  McLachlan and Yentsch
(17) and Nakamura (18), respectively, found that certain bacteria enhanced
the growth of Dunaliella and Chlorella. Ward and Moyer  (14)  and later
Ward,  Moyer, and Vela (25) demonstrated that there was significant reduc-
tion in growth of Chlorella  pyrenoidosa when in the presence of Pseudomonas
aeruginosa.  Opposing opinions can be found regarding the antagonism of
microorganisms to one another.  Guthrie et al. (11) and Geldreich and
Clarke (4) have identified inhibition characteristics between Pseudomonas
aeruginosa and Escherichia coli under different environmental conditions.
     The interactions which occur between bacteria and algae may affect
the physiology and productivity of an aquatic community.   Stimulation of
bacteria by algae or algal exudates has been reported by the following inves-
tigators.  Recent work by Vela and Guerra (52) and  Ward,  et al. (25)
furnished evidence that, in some cases, the proliferation of bacterial
species may be  a function  of algal growth.  In tests involving Shigelia,
Proteus, Staphylococcus, Streptococcus, and Corynebacterium they found
rapid dieoff patterns of these bacteria when exposed to Chlorella.  Yet,
it was also reported that Salmonella typhi and Salmonella paratyphi grew
well in the presence of Chlorella.  In extensive works on toxic blooms of
blue-green algae, Gorham  (36) found that Microcystis produced a toxin but
stated that it did not inhibit bacteria such as Bacillus subtilis , Staphylo-
coccus aureus,  Escherichia coli,  and Pseudomonas hydrophila.  It was
hypothesized that the age of the culture may have been an important factor
in the results and should be considered when analyzing future data.  Fogg
(15, 16) also reported stimulatory effects to bacteria when associated with

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algae.  He attributed those effects to extracellular by-products of the algae.
Lefevre (37) substantiated earlier hypotheses that the extracellular products
did exist.
    The numbers of reports which conclude that algae may be inhibitory to
bacterial growth are  in the majority.  Geldreich and Clarke (4) reported that
fecal  coliform bacteria were influenced adversely by Schizothrix calcicola
within 24 hours.  Telutchenko and Fodorov (5) concluded that their algae
affected the test bacteria by using the carbon dioxide and,  thus,  shifting
the pH, by releasing  antibacterial substances, by inhibiting the bacterio-
phage which Lyse bacteria, and by increasing the organic content which
stimulated  the growth of the bacteria.   They further  concluded that Chlorella
vulgaris was more efficient than Scenedesmus obliquus in killing E... coli
and Salmonella typhimurium.  Chlorella vulgaris  was the test algal species
used  by Pratt and Fong (19). Their conclusion was that that species of
Chlorella was capable of inhibiting the growth of associated bacteria.
    Birge and Judey  in 1929 (28) indicated that algae may have  a role in
reducing the numbers of bacteria in water.  To  date only "Chlorellin"
has been named specifically with regard to  its antibacterial characteristic
by Caldwell (30), Pratt (46), and Spoehr, et al. (50). Flint and Moreland
(35) were able to demonstrate that metabolic exudates of certain blue-green
algae were toxic to bacteria but carried the report no further. Neel and
Hopkins (43) observed the reduction in  numbers  of types of coliforms during
seasons of the year in which prolific algal growth occurred in the ponds.
Work  by Vladimirava (53)  reported that cultures of Chlorella pyrenoidosa
were  definitely capable of suppressing bacterial growth. Prescott (47)
cited  two genera, Microcystis and Chlorella, as being capable  of producing
and secreting substances active against two bacterial genera, Staphylococeus
and Clostridium. Oswald and Gotaas (45),  in an extensive work dealing
with pilot-plant waste stabilization ponds,  proposed that no specific
anticoliform activity could be credited to an algal culture tested in the
laboratory.  However, they did  not discount the possibility of antibacterial
properties  of algae.

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    The problem of bacterial contamination has been overlooked by some
investigators and this is of importance when testing single species of
algae. It is doubtful that there are many bacteria-free cultures of filamen-
tous blue-green or green algae.  Unicellular or diplo forms of blue-greens
and greens are  relatively easy to grow in a bacteria-free state.  In naturally
contaminated cultures, Ward and Moyer (14) reported that the bacterial mass
was less than one percent of the algal mass.  Yet, the numbers of bacteria
were shown to  exceed a million  per milliliter;  figures approaching a billion
per milliliter were not uncommon.  As to the contaminants themselves,
Krauss and Thomas (20) reported Flavobacterium to be the most common and
persistent genus  in cultures of Scenedesmus obliquus.  Levinson and Tew
(21) also  reported Flaveobacterium as a contaminant of their research cultures
of algae.  Their test species was Chlorella vulgaris .
     Numerous  reports are available which quote reductions in the coliform
numbers through waste stabilization ponds.  The reduction percentages are
usually impressive;  however, as Geldreich (1) pointed out, even with
reductions of from 90-99 percent the remaining 1-10 percent  of the coliforms
may easily constitute numbers of from 4x10  to 10x10   per 100 milli-
liters.  These values are not acceptable for more effluent standards.   Most
of the species  incorporated in the coliform group obviously have  a  similar
metabolic pattern of growth and  development.   Geldreich (7)  and  Gallagher
and Spino (8) have observed similar survival characteristics  (or death
rates as the case may be) among the more abundant coliform  species.  In
making observations on streams, Churchill (9) reported that the slopes of
die-away curves  for the total and fecal coliforms were essentially the
same. While figures are usually the best measure of coliform dieoff when
describing their functions, it must be remembered that a rate number does
not relate the environmental conditions. In reports dealing with enteric
bacteria reduction in ponds and series of ponds in South Africa and Zambia,
Marais and Shaw (40), and  later Marais (38,  39) used a value of K = 2.0
for £_._ coli and K = 0.8 for Salmonella typhi.  These differences between
only two  species indicate the need for further data . Projections  made by
use of the modifications of Chick's Law as reported by Marais (38, 39)

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may be used effectively to provide an insight into what general bacterial
pollution control may be required.  Hanes, _et al. (6) reported log death
rates of 0.134/day,  0.29 I/day, and 0.355/day respectively at temperatures
of 10°,  20° and 30°.
    It is apparent that not enough information is available on pathogenic
bacteria such as Salmonella, Shigella, and Vibrio.  With large numbers
of coliforms present, the probability of finding Salmonella, for example,
increases. Of course, with several hundred serotypes of Salmonella in
existence, it would  be difficult to establish the exact nature of the type
found in the sample.  Geldreich (12) reported that when the fecal coliform
count exceeded 1,000, the Salmonella  also increased.   Periodic reports
of isolation of various  species of Salmonella are routine (22).  In March
1969 , 1,165 isolations of Salmonella were reported for humans , an average
of 291 per week.   This was an increase of 13.2 percent over the average
for February 1969, and an increase of 7.0 percent (weekly) for March 1968.
At the same time,  738 non-human isolations occurred during  March 1969.
These figures indicate that, even through few outbreaks  of disease caused
by Salmonella are occurring in this country, the causative agents are ever-
present.  Ward and Moyer (14) reported that Salmonella typhi and Salmonella
paratyphi grew well in algal cultures for periods of time extending through
seven days.  Sidio (48) reported up to 99 percent removal of coliforms
along with complete removal of the pathogenic genus, Salmonella.   There
is additional evidence to indicate that Salmonella typhi  survival is dependent
on the available  supply of nutrients. Increased loadings with shorter
retention times were seen to support the survival of the  typhoid bacillus.
This was reported by McGarry and Bouthillier (41).  They also reported
that ponds with longer detention times and reduced nutrient concentrations
provided a more antagonistic  environment.  Goetzee and Fourie (31)
 showed in field studies that waste stabilization ponds operating in  series
were capable of reducing Salmonella spp. by at least 99.5 percent.  The
total reduction of E. coli was  similar to that found for other bacteria.
 These investigators reported that Salmonella spp. was more  resistant,
 as compared to E. coli, in highly polluted waters.

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    Generally, the operating data on waste stabilization ponds are well
documented (54, 55, 56, 57, 58, 59). Smallhorst and Walton (49) and
Towne,  et al. (51) have observed and reported the reduction of enteric
organisms in waste stabilization ponds.  They attributed this reduction
primarily to detention.  Towne,  et al. (51)  also reported that the  reduction
in coliform numbers was not appreciably  different for the seasons despite
variations in algal concentrations. Detention coupled with short-circuiting
was considered by van Eck (32 , 33, 34) and Bolitho (29) to be the most
important parameter which influenced bacterial concentration.  Reductions
in coliform bacteria of above 90 percent routinely occur in ponds  which
are functioning in an acceptable manner  (42 , 48, 54).  Gann, et al. (23)
found Achromobacter 65 percent of the total population of  pond bacteria,
Pseudomonas 25 percent, Flaveo-bacterium 5 percent, and the coliforms
less than (or rarely equalling) 10 percent.
    One aspect of the dieoff of bacteria  in treatment facilities which has
received very little attention has been the  aftergrowth phenomenon.  After
treatment and discharge,  the surviving bacteria, including those which
have been exposed to chlorine,  may find suitable growth conditions  in
the receiving waters and continue to multiply.  This aftergrowth has been
reported by Orlob (44),  Geldreich  (12), Eliassen (24) and  others.  Under
certain  conditions coliform bacteria were found to increase in numbers
to peak values within 30 hours up to  10-40 times the original number (24).
Even with chlorination of 15 minutes duration, a lesser increase  in after-
growth occurred of 1-12 times the original number of bacteria. Clearly
a greater understanding of the ability of  these organisms to reproduce
and the accompanhing necessary conditions is  needed.

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                             CHAPTER 2
                      MATERIALS AND METHODS

Algal and Bacterial Cultures
    Standard microbiological laboratory procedures were incorporated
during all phases of this investigation.  Algal species were maintained as
bacteria-free as possible under normal  laboratory conditions prior to addi-
tions of the test bacteria.  The axenic algal cultures  were subjected to
transfer from  a solid algal growth medium to a liquid medium, and vice
versa,  for a period of three years prior to the initiation of the experimentation.
Their acclimation to laboratory growth conditions and growth rate constancy
was, therefore,  assured. The composition of the liquid medium which was
used for the culture of the algae in the  laboratory is described in Table 2-1.
This medium was designed to allow optimum growth of the algae for prolonged
periods of time, a feature which was of great benefit  during the extended
periods of testing necessary for successful completion of the investigation.
Table 2-2 presents a breakdown of the elemental concentrations in the algal
growth medium  shown in Table 2-1.
     Throughout the laboratory phase of the investigation six species of
blue-green algae and four species of green algae were used as test orga-
nisms.  These species are listed in Table 2-3 along with the bacteria
which were tested.  Code numbers for the algae indicate their culture
number as  cataloged by the culture collection group at Indiana University
from where they were obtained.  Code numbers for the bacterial species
represent the American Type Culture Collection number or the culture
number from  stock cultures at North Texas State University or both.
     The algae were grown in culture and used in tests at a temperature
of 25 +. 1  C. Fluorescent lighting operating on a cycle of 14 hours on
and 10 hours off provided an  intensity of 290-300 foot-candles .
     All of the bacterial species were cultured in the  laboratory with
trypticase  soy broth or agar supplemented with 2 g/1  yeast extract.
Appropriate serial dilutions were made of the cultures followed by counting
                                  9

-------
                                                          10
     Table 2-1.  Composition of Algal Culture Medium
  Compound
  Final Concentration (mg/1)
NaHCO,
MgSO,
      3 ' 5H2°
KH2P04



NH4NO3



KNC>
            200



              75



              20



             50



             20



             75



             40
   Trace Element Solution (1 ml of the following mixture)
           EDTA



           ZnSO. '  7H O
               T     Z



           H3B°3


           MnCl2 ' 4H2O



           FeSO. '  7H0O
               4     2


           CoCL '  6H0Oq
               2     2


           CuSO. ' 5ELO
           (NH4)6M°7°24
           LiCl
4H20
                      18H20
           SnCl



           KI



           KBr
10.0 g/1



 1.0 g/1



 1.0 g/1



 0.5 g/1



 0.5 g/1



 0.15 g/1



 0.15 g/1



 0.10 g/1



 0.0278 g/1



 0.0556 g/1



 0.0278 g/1



 0.0278 g/1



 0.0278 g/1
       Distilled Water, to make 1  liter final volume


   The pH of the above medium is adjusted to « 5.8 with

  HCl before autoclaving, resulting in a final pH of « 7.4

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                                                                11
Table 2-2 .   Element Concentrations in Algal Culture Medium
Element
N
K
P
Na
C
Cl
S
Mg
Ca
Si
Zn
B
Mn
Fe
Co
Cu
Mo
Li
Al
Sn
I
Br
Final Concentration (mg/1)
41.15
21.245
4.560
58.468
31.825
102.755
20.146
15.150
12.200
2.960
0.228
0.174
0.139
0.101
0.037
0.038
0.054
0.004
0.004
0.015
0.021
0.019

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                                                           12
     Table 2-3.  Algae and Bacteria Test Species
       Organism
  Code Number
Anabaena cylindrica
Anacystis nidulans
Gloeocapsa alpicQla
Oscillatoria chalybia
Oscillatoria formpsa
Phormidium faveolarum
Ankistrodesmus braunii
Chloreila pyrenoidosa
Chlorella vulgaris
Scenedesmus obliquus
Alcaligenes faecalis
Enterobacter aerogenes
Escherichia coli
Proteus viglgaris
Pseudomonas aeruginosa
Serratia  marcescens
Salmonella joaratyphi
Salmonella typhosa
Shigella paradysenteriae
Shigella dysenter_ia_e
Vibrio comma
     B 629
       625
     B 589
     B 386
    LB 390
     B 427
       245
        26
        29
        72
ATCC 8748
ATCC 9621
ATCC 8677  NT 201
ATCC 8427
ATCC 7700  NT 99
ATCC 13880
   NT 113
   NT 118
   NT 131
   NT 127
   NT 154

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                                                                      13
and enumeration of the bacterial colonies on poured plates of the trypticase
soy agar.  This mixture of nutrient sources was found to be superior to
nutrient broth or nutrient agar alone for growth and subsequent enumeration
of most of the test species.  In tests involving laboratory cultures of
                                                                    o
algae and bacteria, counts were made after 24 hours of incubation at 37 C.
The plates were then returned to the incubator and recounted at 48 and 72
hours because, in the majority of cases, the algal contaminants and some
of the test bacteria did  not show adequate growth at 24 hours for accurate
enumeration.  This recounting technique is time-consuming but necessary.
     Two genera of bacteria were the primary contaminants of the filamentous
blue-green test algal species.  These were Brevibacterium and Flavobacterium
and were identified through selective testing  procedures by Dr. R. K. Guthrie.
Their presence  was not  detected in the test cultures of green algae.
     Addition of test bacterial populations to algal cultures was uniformly
controlled throughout the investigation.  A standard straight-wire inoculum
of the bacterial species in question was incubated for 24 hours in half
strength TS  broth.  The solution was mechanically agitated and 0.05 ml
was transferred to each 100 ml of algal culture.  Before removing samples
from the algal cultures  the volume of each 250 ml erlenmeyer flask was
adjusted with  sterile distilled water to correct for evaporation losses.
After making appropriate serological dilutions the samples were plated
onto TS agar and counted.
Laboratory Investigation Series Identification
     The first phase determined the effects that axenic cultures of blue-
green and green algae had on the dieoff of individual species of test bac-
teria.  Additional tests involved studies of algal growth characteristics
when exposed  to the bacteria and studies of the effects of the contaminating
bacteria on various  enteric species.   The tests are described below.
        Series  I.       Viable bacteria were added to individual algal cultures
                       at controlled times (early to mid-log  growth phase of
                       algae) and the'bactericidal or bacteristatic effects
                       noted.  This series of tests  was coded BG-I (blue-
                       greens) and G-I (greens).

-------
                                                              14
Series II.      Viable bacteria were added to individual axenic cultures
              of algae during the first twenty-four hour period of
              the lag growth phase after inoculation of the algae
              into sterile growth medium.  Any inhibition of algal
              growth was determined by this timing sequence.
              The series was coded BG-II and G-II.
Series III.     Control tests were conducted to evaluate normal
              cyclic influences  of contaminant bacteria in algal
              cultures.  This series was coded BG-III and G-III.
Series IV.     Algal mass was determined by weighing procedures.
              Comparison of these data from control cycles with
              data obtained during Series I and II demonstrated
              whether inhibition or enhancement of algal cultures
              was the result of the presence of enteric bacteria.
              This series was coded BG-IV and G-IV.
Series V.      Dieoff rates of the contaminant bacterial species
              were determined during series involving the addi-
              tions of enteric bacteria in algal cultures. This
              series was coded BG-V or "contaminants."
Series VI.     Dieoff rates of the enteric bacteria alone in algal
              growth medium were analyzed.  This series provided
              the basic control  for the study described in Series V
              above.  This series was coded VI.
Series VII.    Separation of the  algal growth medium  into a cell-
              free filtrate during mid-log phase of algal growth
              control with subsequent inoculation of enteric bac-
              teria demonstrated the influences of algal metabolic
              exudates on the enteric bacteria.  This series was
              coded BG-VII and G-VII.
Series VIII.   Equal quantities of each of the six test species  of
              blue-green algae  were mixed when in their mid-log
              growth phase.  Additions of suspensions of indivi-
               dual species of enteric bacteria in each resulting

-------
                                                                     15
                     heterogeneous algal culture demonstrated compara-
                     tive dieoff rates with Series I and II above.  This
                     study was conducted with the blue-greens and the
                     greens separately and was coded BG-VIII and G-VIII.
       Series IX.     Duplication of series BG-VIII  and G-VIII using
                     mixtures of all the enteric bacterial test species
                     provided bacterial dieoff rates which might be
                     expected from field conditions.   This series  was
                     coded BG-IX and G-1X.
       Series X.      Testing in the majority of the series was continued
                     for periods up to 90 days  to establish patterns of
                     aftergrowth of each bacterial  species.  This  series
                     was coded BG-X and G-X.
Laboratory Data Analyses Methods
    Data for all of the series, I through X, and for the runs involving the
pathogenic bacteria, were analyzed using a method of least squares.  The
program (BETA) is shown in Appendix C.  It should be noted that when after-
growth occurred, the data were not  subjected to statistical analysis.  In
order to be acceptable, only decreases in numbers which extended  over
periods of 90 days were programmed.   Data for aftergrowth characteristics
are presented separately. Basically, the function of program  BETA  was the
calcultion of the constants for an equation similar to the following:
Y is the dependent variable, X is an independent variable, and C is con-
stant.  Equation 2-2 was used tc calculate the log (base 10) death rates:
                                     ,  /-.  v                   9-?
                                     + I /_ A.                  £  £
where
        X,
                         log (Y) =
             = the density of bacteria in number per ml, or mg/1 weight
             = the Y-axis intercept
             = the time in days corresponding to Y
             = the death rate coefficient,  log base 10

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                                                                     16
Additional computer output provided:  (a) the variance ratio from the hori-
zontal line; (b) variance about the regression line; and (c)  the multiple
correlation coefficient.   Data  were  analyzed at the 90 percent confidence
limit.
Laboratory and Field Waste Stabilization Pond Studies
     Additional data were obtained from model waste  stabilization ponds.
These laboratory units consisted of two serial connected aquaria similar
to those described by Malina  and Yousef (60).  The total capacity was
46 liters.  A diagram of these units is shown in Figure 4-1.  All of the
model pond experiments were  conducted at ambient temperature on location
at the Govalle Wastewater Treatment Plant in Austin, Texas.  Lighting was
provided by banks of fluorescent bulbs held at  approximately 25 cm above
the  water surface.  The intensity was 325-350  foot-candles during the 12
hours they were cycled.
     Three different design concepts were represented by the model ponds.
The volumes and detention times were calculated to  correspond to the
series of full-scale ponds existing at the Govalle facility.  The first set
of ponds consisted of an anaerobic pond followed by two 46-liter faculta-
tive ponds and a maturation pond.  The second set was represented by
facultative ponds which contained  an anaerobic "trench,"  followed by a
maturation pond.  The third set contained facultative ponds followed by
a maturation pond.
     Daily additions of 500 ml untreated domestic wastewater were added
to each model pond; a similar quantity was removed from the opposite end
to effect a balanced system,  and evaporation losses were corrected by
the  addition of tap water.

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                             CHAPTER 3
             LABORATORY CULTURE DIEOFF EXPERIMENTS

    Regardless of the degree of laboratory control, considerable variance
occurred in the bacterial population during some of the tests .  These fluctua-
tions in numbers were mainly attributed to the growth  phase of the algal
cultures  and the inherent nature of bacteria to adhere  to filaments or aggre-
gates of algae.  The fluctuations also resulted in low multiple correlation
coefficients and high variances.  All results of  the analyses made during
the laboratory axenic culture series are presented in Tables A-l through
A-72 of Appendix A. Those data represent the analyses of laboratory data
as taken from program BETA printouts.
     Column headings in Tables  A-l through A-72  inclusive, Appendix A
are as follows:
        N    = number of data points used in computing that particular
               regression line
        S 2  = the variance of  data points about the mean of all data
         H
               points
        S 2   = the variation of data points about the  regression line
         r
        S 2/S2= the variance ratio which if referenced against  appropriate
               standard "F" tables would indicate the statistical validity
               of the data
         b     = calculated y - intercept
         k     = the dieoff (-)  or growth (+) rate coefficient of  the typical
                          kt
               C  =Cn 10  formulation
         R     = the multiple correlation coefficient
 The numbers of data points indicated for each experiment do not necessarily
 correspond to  the total number obtained during the duration of the run.
 Where significant  aftergrowth of  test bacterial populations occurred, the
 test results were not included  in the computer  program and those data are
 discussed separately.
                                   17

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                                                                      18
Enteric Bacteria  Dieoff Studies
    Although single species of bacteria do not exist in nature with axenic
cultures of algae, without these basic data it would be impossible to assess
the true value of each algal species with  respect to its effect on the dieoff
rate of the bacteria in question.  Dieoff rate coefficients for  virtually all
of the laboratory series involving axenic  algal cultures and enteric bacteria
are presented in Table 3-1. Considering  the series involving the blue-green
algal test species, it is easily discernible that no two species  exerted the
same dieoff effect on any two bacterial species.  Additionally,  the dieoff
rate coefficients vary considerably.  One primarily important conclusion
which is  derived after examination of the data  in Table 3-1 is that the com-
paratively rapid  dieoff rates of enteric bacteria which occur in nature are
apparently not due to the effects of individual  algal species.
    Differences in the  dieoff  rate coefficients (hereinafter called "coefficients")
between series BG-I and BG-II were minimal.  There was little  difference
in the effects which algae had on the dieoff rates of the test bacteria when
the algae were exposed to the bacteria during algal log growth phase (Series
BG-II) or algal log growth phase (Series BG-I).  Several of the coefficients
seen in Table  3-1 appear with relatively  high ranges,  as for example, fil-
trate of Anabaena cylindrica and Alcaligenes faecalis , -. 0230 + . 0570 day
As in this example, some actually exceed the numerical values of the coef-
ficients themselves.  It is believed that  significant fluctuations occurred
in the bacterial  populations throughout the experiment duration  because of
aggregation and adhesive phenomena which are constantly occurring.  For
these reasons the seemingly high coefficient ranges are not to be regarded
as errors.
    On the other hand, comparatively low coefficients were  due to the
abilities of the test bacteria to derive nutritional benefits from the cellular
materials of the blue-green algae. One  such material was the gelatinous
matrix which is  a characteristic of all the blue-green algae.  Additional
evidence  of these occurrences can be seen by the coefficients derived from
the tests using  blue-green algal filtrate.  On a comparative basis it appeared
that prolonged survival of  enteric bacteria occurred when  blue-green algae
were present as compared  to green algae.

-------
                 Table 3-1.  Dieoff Coefficients for Series Utilizing Axenic Algal Cultures and Enteric Bacteria.
       Series
Alcaligenes
faecalis*
Enterobacter
aerogenes*
                                                       Escherichia     Proteus
                                                       coli*           vulgaris*
                              Pseudomonas    Serratia
                              aeruginosa*    marcescens*
Anabaena cyUndrica
  Mid-log inoc.  BG-I
  Contaminant redn.
    BG-I
  Day-0 inoc. BG-II
  Contaminant redn.
    BG-II
  Filtrate BG-VII
-.0774+.0192    -.0854+.0107   -.0397+.0125  -.1000+.0213   -.0512+.0241  -.0366+.0404
  0157+.0526   -.0175 +.0147   -.0173 +.1320  -.0046+.0118   -.0154 +.0066
  !0582+.0419   -.0816 + .0557   -.1132 + . 0534  -.0687 + .0307   -.0702 +.0104

  .0187 + .0054   -.0159+.0128   -.0175 + .0258  -.0094+.0215   -.0198+.0163
  !o230+.0570   -.0316 +.0832   -.0164 +.0575  -.0253 +.1009   -.0167 +.0548
                                                                -.0027 + .0072
                                                                -.0583 + .0249

                                                                -.0234 + .0157
                                                                -.0118 + .0494
Anacystis nidulans
   Mid-log inoc. BG-I
   Contaminant redn.
    BG-I
   Day-O inoc. BG-II
   Contaminant redn.
    BG-II
   Filtrate BG-VII
-.1145 + .0260   -.1172+.0239   -.0796+.0137  -.0899+.0161   -.0614+.0158 -.0480+.0099
 .0051 + .0275
 .0640 + .0320

 .0197 + .0074
 .0375 + .0684
 .0078 + .0099
 .0448 + .0225

 .0213 + .0114
 .0469 + .0405
.0114 + ..0105
.0596 + .0149

.0161 + .0168
.0212 + .0660
-.0177 + .0453
-.0522 + .0470

-.0279 + .0140
-.0525 + .1060
.0589 + .1216
.0474 + .0136

.0068 + .0263
.0316 + .0873
,0147 + .0059
,0437 + .0306

.0323 + .0133
,0301 + .1084
Gloeocapsa alpicola
   Mid-log inoc. BG-I
   Contaminant redn.
    BG-I
   Day-O inoc. BG-II
   Contaminant redn.
    BG-II
   Filtrate BG-VII
-.0688+.0212    -.1356+.0357   -.0849+.0246  -.1205+.0980   -.0484+.0157 -.0466+. 0301
  .0194 + .0159
  .0868 + .0328

  .0110 + .0130
  .0395 + .0437
 .0606 + .0075
 .0838 + .0278

 .0198 + .0117
 .0596 + .0118
.0802 + .0516
.0494 + .0176

.0271 + .0265
.0656 + .0082
-.0462 + .0217
-.0794 + .0438

-.0139 + .0104
-.0473 + .0309
,0484 + .0157
.0781 + .0272

.0141 + .0130
.0197 + .0460
,0466 + .0301
.0596 + .0179

.0213 + .0111
.0208 + .2174
Oscillatoria chalybia
   Mid-log inoc.  BG-I
   Contaminant redn.
     BG-I
   Day-O inoc. BG-II
   Contaminant redn.
     BG-II
   Filtrate BG-VII
-.0966 +.0386   -.0637 +.0518   -.1255 +.0478  -.1153 +.0199    -.1149 +.0288  -.0607 +.0108
  .0704 + .0311
  .0761 + .0327

  .0110 + .0052
  .0996 + .1473
  ,0341 + .0121
  ,0571 + .0154

  ,0138 + .0066
  .0963 + .1387
,0393 + .1598
,1986 + .0631

,0143 + .0087
.1012 + .2162
-.0468 + .0353
-.1074 + .0450

-.0037 + .0165
-.0949 + .1623
.0234 + .0272
.0614 + .0181

,0006 + .0112
.0847 + .0721
,0285 +  .0226
,0905 +  .0272

,0047 +  .0130
,0805 +  .2214

-------
Table 3-1 Continued
Alcaligenes
Series

Oscillatoria formosa
Mid-log inoc. BG-I
Contaminant redn.
BG-I
Day-O inoc. BG-II
Contaminant redn.
BG-II
Filtrate BG-VII
Phormidium faveolarum
Mid-log inoc. BG-I
Contaminant redn.
•BG-I
Dau-O inoc. BG-II
Contaminant redn.
BG-II
Filtrate BG-VII
Ankistrodesmus braunii
Mid-log inoc. G-I
Day-O inoc. G-II
Filtrate G-VII
Chlorella pyrenoidosa
Mid-log inoc. G-I
Day-O inoc. G-II
Filtrate G-VII
Chlorella vulgaris
Mid-log inoc . G-I
Day-O inoc. G-II
Filtrate G-VII
faecalis*


-.1546 +

-.0410 +
-.2957 +

-.0018 +
-.0761 +

-.0880 +

.0029 +
-.0880 +

-.0195 +
-.0697 +

-.0701 +
-.0857 +
-.0769 +

-.1586 +
-.0743 +
-.0925 +

-.1255 +
-.1003 +
-.0852 +
Enterobacter
aerogenes*


.0224

.0139
.2187

.0139
.3122

.0431

.0142
.0275

.0630
.1664

.0193
.0435
.2780

.0219
.0942
.2509

.1253
.0137
.1884


-.0910 +

-.0278 +
-.2218 +

-.0051 +
-.0732 +

-.0640 +

-.0368 +
-.0594 +

-.0174 +
-.0841 +

-.0764 +
-.0801 +
-.0965 +

-.1013 +
-.1265 +
-.0851 +

-.0949 +
-.1138 +
-.0656 +


.0450

.0191
.5164

.0158
.1638

.0460

.0216
.0367

.0189
.1405

.0172
.1205
.1696

.0781
.0148
.2041

.0858
.0155
.1201
Escherichia
coli*


-.0864 -f

-.0182 +
-.2275 +

-.0120 +
.0136 +

-.0966 +

-.0196 +
-.0552 +

-.0262 +
-.0646 +

-.0365 +
-.0542 +
-.0520 +

-.0624 +
-.0763 +
-.0708 +

-.0464 +
-.0407 +
-.0553 +



.0393

.0194
.0640

.0132
.0965

.0599

.0137
.0313

.0235
.2584

.0290
.1598
.0090

.0305
.1384
.3320

.0480
.1286
.1392
Proteus
vulgaris*


-.0964 +

-.0250 +
-.2231 +

-.0124 +
-.0678 +

-.1782 +

-.0266 +
-.1567 +

-.0142 +
-.0643 +

-.0756 +
-.0745 +
-.0904 +

-.1800 +
-.0552 +
-.0830 +

-.1826 +
-.1352 +
-.0757 +
Pseudomonas
aeruginosa*


.0507

.0272
.1002

.0044
.1897

.0757

.0347
.1194

.0247
.0767

.0288
.3424
.0590

.1094
.0419
.2321

.4619
.0176
.1238


-.0795 +

-.0428 +
-.0751 +

-.0058 +
-.0568 +

-.1378 +

-.0188 +
-.2437 +

-.0047 +
-.0704 +

-.1129 +
-.1977 +
-.0890 +

-.0985 +
-.0574 +
-.0550 +

-.1092 +
-.1901 +
-.0683 +


.0379

.0219
.0260

.0101
.0728

.0348

.0084
.0778

.0085
.1549

.0504
.0297
.0751

.0767
.1100
.3776

.0581
.0171
.2253
Serratia

marcescens*


-.0679 +

-.0451 +
-.0709 +

-.0129 +
-.0671 +

-.0999 +

-.0515 +
-.0456 +

-.0542 +
-.0811 +

-.0620 +
-.1753 +
-.0558 +

-.0855 +
-.0552 +
-.0686 +

-.0651 +
-.0989 +
-.0644 +


.0159

.0309
.0165

.0352
.2056

.1055

.0308
.0254

.2044
.1332

.0438
.0254
.1196

.0481
.0787
.3630

.0547
.0148
.2491

-------
Table 3-1 Continued
                      Alcaligenes       Enterobacter     Escherichia     Proteus          Pseudomonas    Serratia
Series                 faecalis*         aerogenes*       coli*           vulgaris*         aeruginosa*     marcescens*

Scenedesmus obliquus
   Mid-log inoc. G-I   -.0458 +.0365   -.0574 +.0238   -.0583 +.0215 -.0891 + .0506   -. 0777 +_. 0357 -. 0974 +_. 0354
   Day-O inoc. G-II    -.0655 +.0142   -.0792 +_. 0065   -.0541 +_. 0631 -.0629 + .0093   -.0466 +.2023 -. 0492 +_. 1126
   FiltrateG-VII        -.0324 +.0214   -.0508 +.0307   -.0401 + .0352 -.0151 + .0809   -.0550 +.0852 -.0325 +.0908

   Mixed blue-greens,
    single bacteria
    inoc. BG-VIII      -.2463 + .3895   -.2368+.5988   -.1666 +.1590 -.2392 +.6491   -.1730 +.1538 -.1479 + .2096
   Mixed blue-greens,
    mixed bacteria
    inoc. BG-IX       -.2600 +.4379   -.2741 +  .7115   -.1081+2.433 -.1632 +.4947   -.1536 +.1237 -.1397 +.0671
   Mixed greens,
    single bacteria
    inoc. G-VIII       -.1635 +.0689   -.1462 +.0353   -.1280 +.0773 -.1912 +.4282   -.1744 +.0601 -.1493 +.0567
   Mixed greens,
    mixed bacteria
    inoc. G-IX        -.1176 +.3440   -.2082 +  .2771   -.1417 +.1001 -.1743 +.5893   -.1493 +.1280 -.1579 +.0885
Brevibacterium sp. ,
effect on dieoff of ...  -.0513+.0300   -.0494+.0127   -.0755+.0123 -.0951 + .0178   -.1011 + .0407 -.0624+.0168

Flaveobacterium sg. ,
effect on dieoff of ...  -.1437 +.0945   -.1616 +.0743   -.0947 +.0431 -.1520 +.0306   -.1042 +.0519 -.0666 +.0333

Bacteria alone, dieoff
in algal growth medium,
VI                    -.0228+.0279   -.0097+.0317   -.0214+.0263 -.0149+.0325   -.0133+.0222 -.0098+.0283

Bacteria alone, anaerobic
dieoff rates of ...      -.0131+. 0253   -.0352 +.0175   -.0490 +.0072 -.0131 +.0307   -.0315 +.0259 -.0563 +.0108         to

-------
Table 3-1 Continued
Series
Alcaligenes
faecalis*
                                       Enterobacter     Escherichia      Proteus
                 aerogenes:
coli*
vulgaris *
Pseudomonas   Serratia
aeruginosa *    rnarcescens *
Growth rates during Series I
   Anabaena cylindrica
    Control .0130 +
    .0021               .0117 + .0099

   Anacystis nidulans
    Control .0171 +
    .0111               .0116 + .0148

   Gloeocapsa alpicola
    Control .0041 +
    .0071               .0083 + .0128

   Oscillatoria chalybia
    Control .0121 +
    .0021               .0084 + .0059

   Oscillatoria formosa
    Control .0290 +_
    .0077               .0285 + .0174

   Phormidium faveolarum
    Control .0025 +
    .0018               .0013 + .0116

   Ankistrodesmus braunii
    Control .0085 +
    .0021               .0074 + .0051

   Chlorella pyrenoidosa
    Control .0199 +
    .0121               .0143 + .0091
   Chlorella vulgaris
     Control .0102 +
     .0037
   Scenedesmus obliquus
     Control .0075 ±
     .0065               .0071 + .0091
                  .0107+.0079     .0043+..0139   .0114 +.0143    .0155 +.0101   .0152 +.0093
                  .0112 + ,0101     .0131 + .0034   .0064 +.0083     .0102 +.0173   .0113 +.0095
                  .0070 +.0072     .0085 +.0076   .0039 +.0109     .0049 +.0050   .0119 +.0060
                  .0067 + .0048     .0049 + .0123   .0189 + .0078     .0155 + .0101   .0152 +  .0093
                  .0256 + .0115     .0209 + .0146   .0160 +.0197     .0101 +.0176   .0159 +.0187
                  .0005 + .0094     .0027 + .0088   .0048 +.0148     .0019 +.0118   .0059 +.0119
                  .0042 + .0061     .0087 +.0071   .0027 +.0031     .0049 +.0008   .0111 +.0029
                  .0171 + .0061     .0171 + .0091   .0199 +.0210     .0100 +.0067   .0121 +.0077
  .0177+.0041    .0120+.0141     .0200 +.0040   .0099 +.0061     .0154+.0071   .0136 +.0088
                  .0089 + .0072     .0101 + .0214   .0116 +.0100     .0171 +.0065   .0144 +.0061
                                                                                                          tsj
            _ i

-------
                                                                       23

      Additional data on dieoff effects of enteric bacteria were obtained
using a  typical soil inhabitant blue-green algal species, Nostoc muscorum.
Filtrate  from an actively growing axenic culture of this organism was exposed
to the enteric bacteria in the same manner as  the other filtrate series .
Since Nostoc is not ordinarily found as a phytoplankton member in waste
stabilization ponds, all  of the series of combinations were not run on this
organism.  The data for the filtrate run with Nostoc  (Appendix A, Table A-50)
are included and intended for  comparison with the data for the other enteric
bacterial-algal runs. The  coefficients were:  Alcaligenes, -.0862 + .2171
day"  ; Enterobacter, -. 1021 +. 1180 day" ; Escherichia, -.0881+ .1177
day"  ; Proteus, -. 102 1 + .0078 day"  ; Pseudomonas, -.0639+  .1352 day"  ;
Serratia, -.6020 +_  .0953 day   . These are comparatively higher rates than
those obtained for many  of the filtrate runs involving the other six species
of blue-greens.  The most  pronounced effect on any bacteria by Nostoc was
that exerted on Serratia. This bacteria appeared to  be more resistant as
compared to the other species, yet the coefficient was-0.602 +_ .0953  day
      Few genera were found to be persistent contaminants of the blue-green
algal cultures. Brevibacterium and Flaveobacterium were the two most
frequent contaminants,  occurring primarily in filamentous blue-green species.
Coefficients for these two  bacterial genera in control runs of the test blue-
green algae are shown in Table A-25, Appendix A.   When enteric bacteria
were present, definite inhibitory effects were noted in the coefficients for
the culture contaminants (Table 3-1).  At the  same time, pronounced antag-
onistic  effects of the enteric bacteria were noted, exerted by the contaminants
Coefficients were higher when the enterics were in  the presence of Flaveo-
bacterium as compared to Brevibacterium. Coefficients for enteric dieoffs
were higher when in the presence of Flaveobacterium alone than when in
the presence of many of the axenic algal cultures ,  further evidence that
blue-green protoplasmic constituents were furnishing nutritional compounds
to the enteric bacteria.
      A comparison of these coefficients with those obtained when the enteric
bacteria were placed in  the sterile algal growth medium (Series VI control) is
noteworthy because of the differences which occurred as a result of any

-------
                                                                       24
biological antagonism.  Dieoff of enteric bacteria in algal growth medium under
anaerobic and aerobic conditions was similar,  for the most part, to dieoff when
the enterics were present with the algae (Series BG-I, BG-II).   Considering
the trace quantities of nutritive organics which were present in the algal
growth medium,  those data demonstrate the persistent nature of the enteric
bacteria and their ability to survive in situations which would  be considered
inadequate for life support of the bacteria.
      Of the four species of green algae studied,  Chlorella pyrenoidosa and
C.  vulgaris exerted more antagonism than did Scenedesmus obliquus  or
Ankistrodesmus  braunii.  Approximately similar dieoff rates for the enteric
bacteria occurred when in the presence of Scenedesmus obliquus and Ankistro-
desmus braunii and all  the blue-green algae tested.  Possibly  Chlorella pro-
duced some substance  such as chlorellin which was responsible for the
accelerated dieoff of the enterics.   Numerically larger coefficients were
obtained for the series  employing filtrate from  the green algae  (G-VTI).  Most
of these coefficients were higher than those developed by the  blue-green
algae under similar circumstances.
      Perhaps the most significant runs were those incorporating mixed  algae
and the additions of single bacterial and mixed bacterial species. The
resulting  coefficients are shown in Table 3-1.  Competition among algal
species for survival apparently accelerated the dieoff of  the bacteria.  Coef-
ficients calculated for  the individual bacterial species were similar to the
rates for the same individual bacterial species when in mixed  culture (com-
paring BG-VTII and BG-IX; G-VIII and G-IX). Oddly enough, in these  series
a significant number of the coefficients were higher for the mixed blue-green
species than for the mixed green species.  These data  infer that the  blue-
green algae secreted antibacterial  substances  when in the presence of other
blue-greens, whereas the green algae tested secreted their antibacterial
materials in heterogeneous  populations or in axenic culture.  No runs were
conducted with green algal contaminants due to their near total absence from
the cultures of green algae.   For the mixed enterics with mixed blue-green
algae and separately with mixed green algae,  coefficients were computed
for the  total numbers of enterics present. The data are as follows: mixed

-------
                                                                       25

blue-greens and enterics, -0.1536 + .0990 day~ ;  mixed green algal species
and enterics, -.1487 + .0935 day"  .  These coefficients would correspond
to what is ordinarily considered to be a "total coliform" count dieoff coef-
ficient.
      Only a small but significant part of the total research effort was devoted
to establishing the effects of the presence of enteric bacteria with algae.
Biomass of controls  (axenic algal cultures) were compared with samples taken
during Series I runs.  Coefficients representing these effects are presented
last in Table 3-1.  In some instances, the presence of the enteric bacteria
effected a reduction in the total biomass  productivity of the test algal species,
Pathogenic Bacteria Dieoff Studies
      Five species of pathogenic bacteria were subjected to tests which were
similar to those involving the enteric bacteria.  The dieoff coefficients for
those series are presented in Table 3-2 and Tables A-58 through A-72,
Appendix A.  Considering the difficulty encountered in maintaining those  pure
cultures of pathogens in the laboratory, their dieoff was slower when  in the
presence  of algae; however, no aftergrowth was found for any of those bac-
terial species.  Considering the coefficients in Table 3-2,  it would appear
that the blue-green and green algal test species had  approximately the same
 effect on those bacteria as they did on the enteric  species.  Surprisingly,
 the mixed algal cultures did not exert as great an  effect on the dieoff coef-
 ficients of the pathogens as on those of  the enteric bacteria.  Coefficients
 produced under anaerobic conditions were significantly lower than the rates
 in the same medium under aerobic conditions.  Therefore it may be concluded
 that the algae had little effect on the pathogenic bacterial species.
 Aftergrowth Potential Measurements
       Extending  the duration of the runs  involving  the test bacteria permitted
 evaluation of one of .the original purposes for this  investigation; namely,
 identification of any aftergrowth potentials of  each bacterial species  tested.
 Of the eleven species of bacteria tested, three demonstrated abilities to
 regenerate their populations . These were Serratia marcescens , Pseudomonas
 aeruginosa, and less frequently,  Escherichia coli. The other enteric bac-
 terial species as well as the pathogens  apparently did not  possess this

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Table 3-2.  Dieoff Coefficients for Series Utilizing Pathogenic Bacterial Species
Salmonella
Series
Mid-log inoculation of ...
Anabaena cylindrica
Anacystis nidulans
Gloeocapsa alpicola
Oscillatoria chalybia
Oscillatoria formosa
Phormidium faveolarum
Ankistrodesmus braunii
Chlorella pyrenoidosa
Chlorella vulgaris
Scenedesmus obliquus
Mixed blue-green species
Mixed green species
Dieoff rates in algal
growth medium, Aerobic
Dieoff rates in algal
growth medium , Anaerobic
paratyphi*

-.0751
-.0840
-.0657
-.0613
-.0839
-.0790
-.0726
-.0950
-.0669
-.0833
-.0759
-.1553

-.0622

-.0207

+
+
+
+
+
+
+
+
+
+
+
+

+

+

.0098
.0174
.0401
.0309
.0199
.0106
.0193
.0495
.0334
.0276
.0259
.0617

.0454

.0293
Salmonella
typhosa*

-.0601 +
-.0758 +
-.0609 +
-.0523 +
-.0684 +
-.0602 +
-.0658 +
-.0986 +
-.0572 +
-.0700 +
-.0775 +
-.1156 +

-.0775 +

-.0268 +
Shigella

paradysenteriae*

.0351
.0157
.0156
.0303
.0093
.0195
.0181
.0386
.0317
.0381
.0244
.0402

.0174

.0262

-.0707 +
-.0981 +
-.0832 +
-.0673 +
-.0622 +
-.0791 +
-.0730 +
-.0996 +
-.0633 +
-.1061 +
-.0564 +
-.1702 +

-.0738 +

-.0492 +

.0141
.0317
.0087
.0330
.0071
.0181
.0250
.0261
.0322
.0411
.0187
.0586

.0276

.0146
Shigella

dysenteriae*

-.0742 +
-.1249 +
-.0745 +
-.0717 +
-.0688 +
-.0670 +
-.0707 +
-.0840 +
-.0700 +
-.0935 +
-.1124 +
-.1345 +

-.0728 +

-.0194 +

.0139
.0208
.0091
.0178
.0217
.0186
.0272
.0520
.0261
.0440
.0673
.0457

.0256

.0346
Vibrio
comma*

-.0511 +
-.0997 +
-.0755 +
-.0639 +
-.0706 +
-.0658 +
-.0593 +
-.0747 +
-.0465 +
-.0872 +
-.0933 +
-.1460 +

-.0625 +

-.0162 +



.0137
.0247
.0329
.0082
.0149
.0166
.0146
.0383
.0283
.0480
.0272
.0535

.0204

.0211
*log1(]day~
                                                                                                               K>
                                                                                                               CT)

-------
                                                                     27
capability under the conditions of testing during these experiments.  Data
for the aftergrowth, and times of  occurrences in the test periods are presented
in Table 3-3.  Aftergrowth was caused by the readily available protoplasmic
constituents of the algae as the algae reached their declining or log death
phase.  The danger of recurrence of these bacterial species which showed
the aftergrowth potential is therefore  present when sufficient organic nutrients
are present in the surrounding aquatic environment. And further, regardless
of the efficiencies of removal of any treatment process or design parameter
such as waste stabilization ponds, if absolutely 100 percent kill of these
bacteria is not accomplished, aftergrowth can indeed occur in the effluent
receiving-waters.
Organic Carbon Production by Algae
      Little is known concerning the contribution by algae to the organic
carbon content of waters and the  resulting effects of the organic carbon on
such parameters as bacterial survival or reproduction capacities.  During
Series BG-I, G-I,  BG-VIII,  and G-VIII, measurements were made at the
90-day time period in an attempt to determine the maximum yield of total
carbon and total organic carbon by the algae, or biomass present in culture.
These data are presented in Table 3-4.  Significant amounts of organic
carbon were present in the cultures after 90-days of testing.  Comparison
with the controls reveals by yet another method that  some inhibition by the
enteric bacteria on the overall productivity of the algae occurred.  The con-
tribution by the bacteria to the organic carbon content was negligible in all
cases.  This can be proven due to the fact  that, on the average, it takes
   12
 10   bacterial cells to equal one milligram of biomass weight and the cells
are obviously not totally organic carbon.  Consequently, the total organic
carbon values, as presented in Table 3-4,  may be assumed to have been
derived from the algae themselves .   These levels of organic carbon represent
adequate quantities for, at least, the survival of the enteric  bacteria, if
 not multiplication of same over a period of time.

-------
Table 3-3.  Aftergrowth Characteristics of Enteric Bacterial Species with
                  Single Species of Algae (Series I).
                                                                            28
Algal
Species
Anabaena
cylindrica

Anacystis
nidulans

Gloeocapsa
alpicola
Oscillatoria
chalybia
Phormidium
faveolarum


Ankistrodesmus
braunii

Chlorella
pyrenoidosa

Chlorella
vulgaris
Scenedesmus
obliquus


Bacterial
Genera

Pseudotnonas
Serratia

Pseudomonas
Serratia

Serratia

Pseudomonas

Escherichia
Pseudomonas
Serratia

Pseudomonas
Serratia

Pseudomonas
Serratia

Pseudomonas

Escherichia
Pseudomonas
Serratia
Min. No.
Bacteria
in run, No/ml

10,000
6,000

33,000
48,000

250

310

<100
<100
<100

<2,000
50,400

1,030
286

132

324
4,600
1,290
Day Min.
No.
Occurred

63
63

63
63

56

56

56
63
42

56
63

77
77

63

63
63
63
Aftergrowth ,
Max. No/ml

180,000
800,000

310,000
340,000

8,110

160,000

1,920
3,300
3,320

280,000
542,000

525,000
38,100

4,000

64,200
60,000
41,000
Day Max,
No.
Occurred

70
84

70
84

91

91

84
70
56

91
91

91
91

91

91
91
91

-------
Table 3-4.  Total Carbon and Total Organic Carbon Content of Biomass After Ninety Days
                  (Series EG-I, G-l, BG-VIII, andG-VIII, in mg/1) .
Bacteria Added
Algal Alcaligenes
Species faecalis
T.C.
Anabaena
cylindrica 47

Anacystis
nidulans 36

Gloeocapsa
alpicola 64
Oscillatoria
chalybia 128
Oscillatoria
formosa 100

Phormidium
faveolarum 77
Ankistrodesmus
braunii 62

Chlorella
pyrenoidosa 50
Chlorella
vulgaris 53
Scenedesmus
obliquus 60
Mixed Blue-greens
BG-VIII 92
Mixed Greens
G-VIII 65
T.O.C.
41
34
56
124
88
73
41
37
41
41
58
61
Enterobacter
aerogenes
T.C. T.O.C.
60
49
67
79
198
81
57
61
59
62
83
67
58
45
58
69
154
73
43
50
43
40
49
65
Escherichia
coli
T.C.
47
36
71
64
206
69
67
47
60
61
118
137
T.O.C.
33
34
66
60
166
69
52
40
51
50
95
63
to Algal Culture
Proteus
vulgaris
T.C. T.O.C.
53
38
77
56
200
104
47
51
54
51
169
61
41
36
62
56
166
77
40
45
50
41
124
47
Pseudomonas
aeruginosa
T.C. T.O.C.
51
33
64
62
252
73
47
56
58
53
95
130
41
33
60
62
198
71
38
47
49
38
67
81
Serratia
marcescens Control
T.C.
49
41
58
86
120
69
59
56
55
57
77
94
T.O.C. T.C. T.O.C.
41 77 47
35 52 47
53 67 67
75 65 42
75 172 168
69 85 82
48 54 50
47 97 96
39 54 33
55 51 39
58
c-o
75 <-£>

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                             CHAPTER 4
     LABORATORY AND FIELD WASTE STABILIZATION POND STUDIES

    The objective of these experiments were to establish dieoff coefficients
for selected species of bacteria under conditions which would occur in
operational waste stabilization ponds.  Two kinds of pond systems were
investigated; namely, laboratory scale units which were designed on a
volume detention time basis  to closely correspond to the field units, and
field scale pilot units .
Laboratory Waste Stabilization Pond Studies
     A diagram of the laboratory waste stabilization ponds  depicting the
three different design concepts is shown in Figure 4-1.  Throughout the
test period of approximately  60 days,  supplementary  data were taken on
phytoplankton populations to relate their concentrations to possible effects
on the bacterial populations. The procedure was as follows. A liter of
domestic wastewater was added to each of Series I, II, and  III daily.
Series I  differed  from Series  II and III in that Series I began  the treatment
cycle  with a six-liter anaerobic pretreatment chamber.  Also, on a daily
basis, 0.5 liter of effluent from the anaerobic unit was added to each of
the two following facultative units.   This was followed by the addition
of one liter, combined from each of the two facultative units, to the
maturation pond.  In Series I the volume of the facultative units was 90
liters  and that of the maturation pond was  18 liters.  These volumes pro-
vided  detention times of 6, 90, and 18 days respectively.  The maturation
ponds in  Series I, II, and III were similar.
     Series II facultative  units provided anaerobic treatment in an anaerobic
trench located at the influent end of  each unit.   The  volume of these faculta-
tive units was 84 liters.  The facultative units and the maturation pond
unit in Series III had the  same volume as each of the similar units in
Series I. In Figure 4-1 the locations of bacterial inoculation points (i)
and sampling stations  (numbers) are  shown.  Duplicated sampling station
                                  30

-------
                                      31
SERIES     PRE-
       TREATMENT
        (AWSP)
      INFLUENT
                FACULTATIVE   MATURATION
H
                 tfe
(FWSP)        (MP)
     ^-BAFFLES
^T-
/
^
. _ .
2
*

3
v.
—
4
y
                          \
                          /
                                  INOCULATION
                                  STATIONS
         INFLUENT
              X
        ANAEROBIC
         TRENCH —
        \
        /
        INFLUENT
            X
1
_i
f

V.



8
X


9
v_



10
y
                             SAMPLE
                             STATIONS
/'
v^
^ — __t*
8
>
9
v
10
*
   FIG. 4-1. SCHEMATIC OF LABORATORY PONDS

-------
                                                                     32
numbers mean that equivalent volumes were sampled at those points and
mixed prior to analysis.  Overall, the laboratory waste stabilization pond
units proved to  be amenable to  bacteriological analysis because of their
relatively small size, which permitted accurate  bacterial inoculations.
    Data for all bacteria counts were obtained by  plating duplicates of
two dilutions from each sample.  These data,  representing the statistical
mean values of four counts per sample are presented in Appendix B as Tables
B-l through B-12. Blanks in these tables are the  result of inconsistent
plating; or the  types or species of bacteria in question did not appear on
the plates on that date; or the counts were too high to be statistically
valid.  The gaps do not imply the absence of the bacteria.  Incubation periods
were not consistent throughout the tests for the  following reasons.  In
many instances it was found that room temperature incubation, as opposed
to incubation at 35°C,  enhanced some of the coliform  species as well as
other bacterial species found on the plates used for the total counts.
Also, in several instances, periods  of 72 hours  of incubation were necessary
to obtain representative counts.  This peculiar characteristic of many
bacterial species has been  observed by the authors before.  Therefore,
these data provide a more accurate account of the actual numbers of bac-
teria present at the sampling times than would have been recorded by
incubation for,  say, only 24 hours at 35  C.
     On July 7 and 29 cultures  of Escherichia coli, Pseudomonas aeruqinosa,
and Serratia marcescens were inoculated into the  selected locations in the
laboratory units (Figure 4-1).  The total bacterial  numbers for each inoculum
are presented in Table 4-1.  By taking into account the daily additions of
wastewater,  its complement of the bacteria in question, volumes of the
laboratory ponds and other pertinent quantitative physical factors, dieoff
coefficients for each of the three added species were  calculated.  These
coefficients are shown  in Table 4-2  for the vicinities  adjacent to the point
of inoculation.  In the majority of cases  the dieoff coefficients were much
higher than those found for  the axenic culture experiments .  The exceptions
to this can be  seen in the data in Table 4-2 as  for,  by way of example,
Pseudomonas aeruginosa at station 2.  Obviously, conditions prevailing

-------
                                                                           33
Station*
          Table 4-1.  Bacteria Inoculated Into Selected Stations In
                  Laboratory Waste Stabilization Ponds
                                    Species and Date
  Escherichia
  coli
Tuly 7    July 29
  Pseudomonas
  aeruginosa
July 7      July 29
  Serratla
  marcescens
Tuly 7    Tuly 29
1
2
5
6
7
8
11
13
12
12
11
13
12
11
.2406**
.2579
.4595
.6730
.1105
.5841
.2480
9
13
9
11
9


.3010
.8000
.0000
.3656
.3980
—
—
11
12
12
11
11
11
11
.4700
.1847
.3180
.7136
.8720
.6200
.7780
9
11
11
10
11
11
9
.9030
.6020
.6535
.0608
.9030
.4775
.7401
9.
11.
11.
12.
12.
13.
10.
9607
9240
1760
0415
6445
4345
2600
9.1760
11.3010
9.5440
—
—
9.6020
11.0000
*Locations indicated in Figure 4-1.
**Log  _ total number inoculated.

-------
                                                                          34
Table 4-2.  Dieoff Coefficients of Inoculated Bacteria in Laboratory
                    Scale Waste Stabilization  Ponds
Station Inoculated*

1
2
5
6
7
8
11
Coefficients
Escherichia
coli

-1.03
-0.44
-0.37
-0.31
-0.61
-0.37
-0.51
for Bacterial
Species (day"1)
Pseudomonas Serratia
aeruginosa

-0.34
-0.14
-0.93
-1.00
-1.10
-0.63
-1.26
marcescens

-0.43
-0.41
-1.38
-1.78
-1.53
-1.16
-1.15
*Inoculation point at or adjacent to indicated station; Figure 4-1.

-------
                                                                      35
in the early stages of the treatment units caused higher dieoff coefficients
to occur than did those in the later stages.  Anaerobic pretreatment did not
cause the accelerated dieoff for the three inocula bacteria species,  expecially
Pseudomonas and Serratia, as was  expected.  It might be concluded that
the  corresponding decreases in nutrient materials aided in acceleration of
that dieoff which did occur.  It should be noted, however, that the addi-
tions of the inocula bacteria at station 8 resulted in reduced dieoff coeffi-
cients  for two of the three test species.   Fewer algae were present at that
station during part of the test period than were present at other stations
except station 11 (Table 4-4).
    The  reduced phytoplanktonic concentrations throughout all runs involving
the laboratory ponds in Series III appeared to be a  characteristic of that
series throughout the test period.  Of the three test bacteria,  E. coli
appeared to possess the greatest capacity for survival through  all three
types of pond combinations.  Many of the enteric bacteria remained in
the final  effluents.  Examination of all three  effluents revealed that the
quality of the effluent permitted some aftergrowth of all three test bac-
teria species.   The increases in numbers of bacteria did not exceed two
orders of magnitude.  However, the mere fact that aftergrowth did occur
is  in itself additional evidence that a much greater understanding of the
behavior of these bacteria in ponds is needed.
     Relationships between the bacteriological concentrations and the
 corresponding phytoplankton concentrations may be observed by referring
to  Tables 4-3 and 4-4 and Figures 4-2 through 4-5.  Surprisingly few
 diatoms  were present in any of the treatment units during the course of the
 study.  Euglena sp. did not appear until on or slightly prior to August 20.
 For the purposes of this investigation the intermittent appearances of
 representative species of these divisions (Euglenophyta and Chrysophyta)
 permitted evaluation of  the two divisions which were of primary concern,
 the blue-green  algae (Cvanophyta) and the green algae  (Chlorophyta).
     Considering the behavior of the test species in the laboratory ponds ,
 the following observations were made during the duration of the experiments.
 Periodic increases in concentrations of total bacteria, as noted for day 36

-------
                         Table 4-3.  Phytoplankton Found in Laboratory Waste Stabilization Ponds.
Algal
Division
Stat
Cyanophyta
Euglenophyta
Chrysophyta
Chlorophyta
Total


ion; 3
30,000*
(23,000)**
-0-
1,000
( 1,000)
1,400
(17,000)
32,400
(41,000)
Table 4-3 Continued
Algal
Division
Stat
Cyanophyta
Euglenophyta
Chrysophyta
Chlorophyta
Total


ion: 3
17,000
( 5,000)
1,000
( 1,000)
-0-
10,000
(34,000)
28,000
(40,000)

July 9
6
37,000
( 36,000)
-0-
-0-
1,500
( 2,000)
38,500
( 38,000)


August 20
6
13,000
(144,100)
500
( 400)
-0-
19,500
( 60,500)
33,000
(205,000)


9
-0-
-0-
-0-
6,700
( 8,000)
6,700
( 8,000)



9
4,000
(21,500)
100
( 100)
-0-
6,900
(38,400)
11,000
(60,000)
Date and Station Number
July 23 August 6
36936
17,000 52,000 4,000 10,700 37,200
(31,500) ( 47,000) ( 7,500) ( 7,000) ( 60,000)
— r\ A n — n~ — 0—

-°- , !:Z -°- -°- -«-
3,000 43,000 10,000 2,700 6,000
( 6,000) (187,000) (20,000) (28,000) ( 23,000)
20,000 96,000 14,000 13,400 43,200
(37,500) (235,000) (27,500) (35,000) (290.000)

Date and Station Number








9
-0-
-0-
-0-
4,000
(36,000)
4,000
(36,000)








*Areal StandardeUnits of phytoplankton per ml.
**No. of phytoplankton per ml.
OJ

-------
                                                                           37
           Table 4-4.  Total Phytoplankton Concentrations Found In
                  Laboratory Waste Stabilization Ponds
Date
July 9
July 23
Aug. 6
Aug. 20
3
32,400*
(41,000)**
20,000
(37,500)
13,400
(35,000)
28,000
(40,000)
5
4,100
(12,000)
6,100
(11,000)
6,300
(16,000)
13,000
(27,500)
Station Number
6 7
38,500
( 38,000)
96,000
(235,000)
43,200
(290,000)
33,000
(205,000)
100
( 270)
2,500
( 3,500)
41,900
(52,500)
20,000
(31,500)
9
6,700
( 8,000)
14,000
(27,500)
4,000
(36,0001
11,000
(60,000)
11
3,000
( 6,000)
3,750
(13,000)
1,670
( 4,800)
9,600
(27,000)
*Areal Standard Units of phytoplankton per ml.
**(    ) No.  phytoplankton per ml.

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  7
3  6
     INFLUENT
    STATION 7
    (EFFL. H)

       A/

            STATION
            (EFFL.m)
STATION 5
 (EFFL.I)
   0 Days   10              30      40
             (Sampling Period July 3-Aug. 26)
           50
  FIG. 4-2. TOTAL BACTERIA, LABORATORY PONDS


-------
 •
o
o.

   0 Days
10      20      30      40
  (Sampling Period July 3-Aug. 26)
 FIG. 4-3. TOTAL COLIFORM, LABORATORY PONDS


-------
                   INFLUENT
              STATION 5
              (EFFL.I)
                                 STATION  I
                                 (EFFL.IK
           STATION
           (EFFL
Days
10       20       30      40
  ( Sampling Period July 3- Aug. 26 )
  FIG.4-4.  E.coh, LABORATORY PONDS


-------
                                     41
CO
  10
  9
  8
£" 7 -
  o
"2   6
o x
= r 5
2 e
en   4
  3
  2
  I
  o
  X
O.

o  i
o
    0

                       STATION 6
                STATION 3
       STATION 9
           STATION
                         STATION 9
                STATION 3
          7-9
               7-23     8-6
              SAMPLE  DATE
                               8-20
   FIG. 4-5. PHYTOPLANKTON DENSITIES
          IN  LABORATORY PONDS

-------
                                                                       42
(Figures 4-2),  were followed closely by a sudden increase in the total
coliform count  (day 44, Figure 4-3).  Only a small fraction of the total
coliform count  was attributed to E. coli,  per se.  Examination of the plates
for the  samples in question revealed colonial morphology similar to that for
Enterobacter, Alcaligenes ,  or Proteus ,  rather than Pseudomonas and Serratia .
The total coliform count as  well as the populations of E. coli decreased
significantly on or about July 23  to about August 6 when the phytoplankton
populations were relatively high.  During these times the blue-green popula-
tion was  in the majority. Figures 4-2 through 4-4 relate other pertinent
points.  Acclimitization of the pond systems was  occurring for approximately
thirty days prior to any stabilization of the effluent quality so far as total
coliform or E.  coli concentrations were concerned.  Statistical means were
calculated for  all values of effluent concentrations.  These indicate the
systems' overall capability in reduction of the group or species  in question.
Data for these  follow:

Total Bacteria
Total Coliform
E. coli
Pseudomonas sp.

Influent
6.92
5.87
4.73
Effluent
Series I
(Station 5)
4.95
2.36
2.45
3.83
Effluent
Series II
(Station 7)
5.37
2.34
2.64
3.50
Effluent
Series III
(Station 11)
5.13
2.02
2.00
3.21
The values are all log-^Q  of the mean number per milliliter.  Values were
not calculated for Serratia because of its erratic occurrence and detecta-
bility.  By the same token the presence of Pseudomonas in the influent
wastewater was known and detected; however, detection by standard plate
techniques was hampered due to the difficulty encountered in culturing
this genus at  standard laboratory incubation temperatures.
    The data  presented above demonstrate that pond Series I were the
most efficient in reducing the total bacterial populations.  The  slightly
increased detention time may  have been a contributing factor in this
reduction. For total coliform  bacteria all three series exhibited similar
capabilities; however, Series  III exhibited slightly more  efficiency in this

-------
                                                                     43
regard than did I or II.  Similarly, Series III performed slightly more
efficiently than did Series I or II in reducing E. coli numbers as well as
Pseudomonas.
    Escherichia coli, Pseudomonas aeruginosa, and Serratia marcescens
all exhibited some survival at the three effluent sample stations 5,7, and
11. Some correlation between the phytoplankton concentrations and the
bacterial densities were observed.  Pseudomonas appeared in higher nub-
bers when reduced phytoplankton concentrations were present.  E. coli
apparently was capable of  survival in consistently higher numbers regard-
less of the phytoplankton concentrations.  Serratia  was rarely present in
consistently large concentrations in the  effluents; however, the species
inoculated was apparently  different from that (or those)  present in the
wastewater.  The periodic  increases in Serratia (Tables B-9 and B-10,
Appendix B) were observed to be associated with clumps of blue-green
algae, a phenomenon which is common to all waste stabilization ponds
during the summer and early fall seasons .
    The group of organisms which are reported in Tables B-ll and B-12
of Appendix B,  the chromogens,  includes such genera as Flaveobacterium
and Brevibacterium. These organisms were found to be present in waste-
water in high concentrations. Very little is knownabout their physiology,
pathogenicity  (if any), or their contribution to the overall dieoff of the
coliform group.  From the data presented in Tables  B-ll and B-12 it can be
seen that aftergrowth of these bacterial  genera did  occur in the effluent
sampling station zones 5,  7 and  11.  The comparatively high numbers of
these bacteria may have  been responsible,  at least in part, for a certain
amount  of the  dieoff of the coliforms  and/or test species .  This may have
occurred by either antibiosis or  nutrient competition.  At any rate, Flaveo-
bacterium and Brevibacterium will require considerably more research
effort before their exact contribution  to waste treatment processes can be
effectively  evaluated.

-------
                                                                     44
Field Waste Stabilization Pond Studies
     During and preceding the period of investigation with the laboratory
waste stabilization ponds,  data were obtained on three series of field
waste stabilization ponds.   These data were taken for a three-month period
beginning on June 4 and extending through August 26. A diagram of the
field ponds is  shown in Figure 4-6.  The laboratory waste stabilization
ponds described earlier in the text were designed to approximate the
detention times and types of systems of the field ponds.   Series I was
preceded by an anaerobic pretreatment unit which had a volume of 8,900
cubic feet and a detention time of about 4 days.  The facultative pond in
Series I had a volume of 117,500 cubic feet and a detention time of about
55 days.  The small maturation ponds all had volumes of 18,000 cubic feet
and  detention  times of about 8 days .  Series II and  III facultative ponds
had  volumes of 126,400 cubic feet and 126,300 cubic feet respectively  with
detention times of about 51  days and 59 days each.  Sample stations were
in the vicinities of the numbered areas of the ponds in Figure 4-6.  Surface
samples  were  taken one foot below the surface and  bottom samples  were
taken about one foot from the bottom. This was  done to avoid excessive
concentrations of algae at the surface and excessive amounts of settled
sludge at the bottom.  Data obtained from these 12  sampling points are
presented in detail in Tables B-13 through B-28, Appendix B.  Objectives
of this phase of the investigation were to compare the efficiencies of the
three different types of waste stabilization ponds as to coliform reduction,
to compare the efficiencies  of the field and laboratory scale ponds, and to
attempt massive inocula of selected bacteria for dieoff studies.
     Inoculations with laboratory-cultured bacteria occurred on the  dates
indicated in Table 4-5. The numbers of bacteria which were inoculated
into  those ponds in certain cases proved to be ineffective as tracer method-
ology for dieoff studies. Dieoff of the test species was rapid in the field
ponds.  Calculating by volume of the ponds and daily flow rates from the
influent to the sample stations indicated the following dieoff coefficients
(as log1Q day   ).

-------
                                          45
                  ANAEROBIC
                           MATURATION
               4(S)
               5(B)
      FACULTATIVE
                                         INFLUENT
  FACULTATIVE
               7(S)
               8(B)
       C AMAPRORir
                      MATURATION
                          —I/
   ANAEROBIC TRENCH
                              9(S)
nr
          IO(S)
          1KB)
FACULTATIVE
                           MATURATION
             SAMPLE STATIONS
          (S)-SURFACE  (B)- BOTTOM
 FIG. 4-6. SCHEMATIC OF WASTE STABILIZATION PONDS

-------
                                                                        46
         Table 4-5.  Bacteria Inoculated Into Selected Stations
                     of Waste Stabilization Ponds
Station
2
4
4
7
7
10
10
Date
June 5
June 5
June 16
June 19
July 29
June 23
July 2 1
Escherichia
coli

13.2265*
12.9350
13.7164
13.9235
15.0281
13.4510
14.0720
Pseudomonas
aeruginosa
14.0592
12.9351
14.2812
14.0214
15.1146
14.1565
14.5761
Serratia
marcescens

—
—
14.1763
13.9855
14.4340
14.5513
14.2140
*log. n numbers per ml.

-------
                                                                      47
                                         Sample Stations
Escherichia coli
Pseudomonas aeruginosa
Serratia marcescens

#4
-1.42
-0.89
-1.81
#7
-1.67
-1.10
-2.02
#10
-1.21
-0.91
-.199
These coefficients were, without exception, higher than those found for
the laboratory scale ponds, indicating accelerated antibiotic activites.
Solar radiation contributed to some extent to those accelerated rates.
Data for total bacteria, total coliform bacteria, and phytoplankton popula-
tions are shown in Figures 4-7 through  4-9, and Tables 4-6 and 4-7.
Those data indicate, as in the  case of the laboratory waste stabilization
pond studies, that a period of acclimatization was occurring for approxi-
mately half the test period of three months.  Means of total bacteria,
total coliform bacteria and £_._ coli concentrations were calculated for the
raw influent  (station 1) and the three effluents for the test period.  They
were as follows (as log1Q  No./ml).
                                 Series I     Series II    Series III
                      Influent    Station 6    Station 9    Station 12
      Total Bacteria
      Total Coliform
      E_.  coli
 These values indicate that reduction of the total bacteria was not as effi-
 cient as could be hoped for.  Total coliform bacteria were reduced signifi-
 cantly, with the majority of reduction being due to the dieoff of E._ coli,
 per se.
     Algae which were present in the ponds throughout the test period were
 predominantly blue-green and  green algae, as was the case for the labo-
 ratory waste stabilization ponds.  Surprisingly high concentrations of
 algae were found at the surface of the anaerobic pretreatment pond of
 Series I, contributing, no doubt, to some aerobic activity.  There appeared
 to be  a direct relationship between the high phytoplankton concentrations
 in August and consistently lower coliform counts.  Increases in total coliform
7.14
5.83
5.26
5.04
1.35
0.34
4.91
1.31
0.78
5.25
1.37
0.57

-------
'. r
•
•
-
                                                           STATION
                                                           (INFLUENT)
                                                         STATION 12
                                                           EFFL JH
                                            STATION  9
                                             (EFFL.n
                                    STATION 6
                                    (EFFL.I)
0 Days 5
15
20
                            25   30   35    40   45    50    55    60   65    70
                                 ( Sampling  Period June 4 - Aug. 26 )
                  FIG. 4-7. TOTAL BACTERIA  IN  WASTE STABILIZATION PONDS
75   80   85


-------
~ 5
 o
 C7>
 O
- 4
-,
>\
STATION 6
                    /;
                    / <
                   /  i
                         STATION 9
                           (EFFL. H)
             (EFFL. I)  '  ',
                                       STATION 12
                                       (EFFL. HI)
   0 Days 5    10    15   20   25   30   35   40   45   50   55   60   65   70
                              ( Sampling Period June 4 -Aug. 26)

                 FIG. 4-8. TOTAL COLIFORM  IN WASTE STABILIZATION PONDS
                                                               75   80
                                                                                 85


-------
                                      50
en
  10
   9
   8

-------
                                Table 4-6.  Phytoplankton Found in Waste Stabilization Ponds


Algal
Division
Station: 4
C y_a ripphyta.
Euglenophyta
Chrysophyta
Chlorophyta
Total
5,000*
( 7,500)**
-0-
-0-
19,100
( 42,500)
24,100
( 45,000)

June 1 1
7
5,500
( 4,800)
-0-
-0-
15,000
(3_1,200J
20,500
(36,000)


10
4
( 2
1
( 1
,100
,500)(
,500
,750)(
-0-
37
(612
43
(617
,500
,750)(
,100
,000)(
Date
4
4,200
8,000)
600
650)
-0-
40,150
51,350)
45,000
60,000)
and
Station
June 25
7
5
( 5
,000
,000)
-0-
-
20
(22
2b
(27
0-
,000
,500)
,000
,500)
Number
10
1,500
( 4,700)
-0-
-0-
47,500
(445,300)
49,000
(450,000)

4
7,000
( 22,000)
-0-
-0-
24,500
L27,OOOJ_
31,500
( 49,000)

July 2
7
3,400
( 3,000)
4,000
( 3,000)
-0-
6,100
( 8,0001
13,500
(14,000)

10
21,000
( 24,500)
6,000)
( 4,500)
-0-
54,000
(488,000)
81,000
(517,000)
Table 4-6 Continued


Algal
Division
Station: 4
Cyanophyta
Euglenophyta
Chrysophyta
Chlorophyta
Total
72,000
(145,000)
-0-
-0-
9,000
( 20,000)
81,000
(165,000)

July 23
7
9,000
(17,000)
-0-
900
( 1,000)
16,000
(57,000)
25,400
(75,000)

1
1
(
-1

.0
,000
50 OX
3- ,
-0-
3
( 19
4
( 20
,900
,500)(
,900(
iOOO)(
Date
4
20,000
8,000)
1,000
1,000)
-0-
4,000
123,000)
25,000
132,000)
and
Station
August 6
7
21
(10
1
( 1

44
(50
67
(62
,200
,000)
,500
,200)
0-
,300
,800)
,000
,000)
Number
10
15,500
( 12,000)
250
( 100)
-0-
5,250
( 13,400)
21,000
( 25,500)

4
3,000
( 2^000]
2,000
( 1,000)
-0-
13,000
(207,000i_
17,000
(210,000)

August 20
7
82,000
(17,000)
-0-
-0-
11,000
(22,000)
93,000
(39,000)

10
-0-
-0-
-0-
40,000
( 27,000)
40,000
( 27,000)
*Areal Standard Units of phytoplankton per ml.
**( )  No. of phytoplankton per ml.
en

-------
                           Table 4-7.  Phytoplankton Concentrations Found In Waste Stabilization Ponds
Station Number
Date
June 11
June 25
July 2
July 23
Aug. 6
Aug. 20
2
1,100*
( 900)**(
2,100
( 1,300)(
96,900
(2,001,000)(1
16,670
( 27,200)(
13,700
( 20, 000) (
17,500
( 25,500)(
3


3,
,009
60
80
7
13
6
11
4
500 24,
400) ( 45,
250 45,
100) ( 60,
600 31,
,000)( 49,
,000 81,
,000) (165,
,500 25,
,500) (132,
,500 17,
,500) (210,
5
100 22,500
OOOX 30,000)
000 30,000
OOOX 27,000)
500 28,700
000)( 55,000)
000 88,000
000)(175,000)
000 22,500
OOOX 35,750)
000 19,500
000)(218,000)
6
7,000
( 13,000)
6,500
( 12,500)
6,400
( 17,000)
66,000
(285,000)
25,500
( 38,500)
40,000
( 67,500)
7
20,500
(36,000)
25,000
(27,500)
13,500
(14,000)
25,900
(75,000)
67,000
(62,000)
93,000
(39,000)
8
17,000
(22,500)
7,900
(15,000)
4,600
( 6,000)
2,000
( 3,000)
11,500
(13,000)
21,000
(19,000)
9
5,500
(11,000)
4,900
( 7,200)
9,800
(23,000)
19,700
(21,000)
21,500
(30,000)
8,100
(13,400)
10
43,100
(617,000)
49,000
(450,000)
81,000
(517,000)
4,900
( 20,000)
21,000
( 25,500)
40,000
( 27,000)
11
11,000
( 13,500)
6,200
( 12,500)
31,900
(555,000)
5,000
( 38,000)
13,700
( 33,000)
1,000
( 1,100)
12
2,700
( 3,500)
3,850
( 14,000)
26,000
(380,000)
7,850
( 43,000)
7,000
( 11,000)
14,000
( 17,500)
*Areal Standard Units of phytoplankton per ml.
**(   )  No. of phytoplankton per ml.
                                                                                                                                en

-------
                                                                      53
counts in late August (day 70 on) corresponded closely with the compara-
tively lower algae counts for the period.
    Survival of Pseudomonas sp. in these ponds was apparently very
difficult as can be seen by the data  in Tables B-22 through B-24.  Some
carryover and aftergrowth was evident in the maturation pond of Series III
(station 12). That particular station had a bloom of Brachionus around
July 17 in concentrations of up to 200  per milliliter in the surface waters.
Those large  numbers should have significantly reduced the bacterial popula-
tion in that time period; however, no significant reduction was  noted.
On many occasions the concentration of coliform bacteria were lower in
the deeper waters than in the surface waters.  It is  entirely possible
that a greater amount of antibiotic activity was occurring in the deeper
waters.  Apparently few Serratia  sp. were present in the influent waste-
water.  Those individuals which  were  present appeared to survive until
reaching the facultative or maturation  ponds.  Some aftergrowth of this
genus was observed in the maturation  ponds.  The chromagens exhibited
very low, if any, dieoff in most instances.  Their higher numbers may
have contributed to the overall comparatively efficient reduction of the
coliforms .  It is clear that the field waste stabilization  ponds were
more effective in bacterial reduction than were the laboratory units,  so
far as the coliform group were  concerned.
     These investigations on the field pilot waste stabilization ponds
and the laboratory ponds were  accomplished in conjunction with investi-
gations in progress under grant WTRD 178-01-68, Federal Water Pollu-
tion Control Administration,  "Design Guides for Selected Wastewater
Treatment Processes."
     With the information presented by this investigation, remaining
efforts in this important area of sanitary  engineering should be directed
toward establishing:  (a) guidelines  on amounts of disinfectant necessary
to eliminate proportions of enteric bacterial populations to meet effluent
specifications;  and  (b) cost-benefit specifications  based on the as  yet
unknown pathogenicity of other bacterial species found  in waste stabiliza-
tion ponds and related wastewater treatment systems. An undeniable
need exists at the present time for this information.

-------
                                BIBLIOGRAPHY

 1.     Geldreich, E.  E.  "Sanitary Significance of Fecal Coliforms in the Environ-
            ment," Water Poll. Control Research Series Publication No. WP-20-3,
            U.  S. Dept.  of the Interior, F.W.P.C.A. (Nov., 1966).

 2.     Gravel, A. C., Fruh, E. G., Davis, E. M.  "Limnological Investigations
            of Texas Impoundments for Water Quality Management Purposes - The
            Distribution of Coliform Bacteria in Stratified Impoundments," Center
            for Research in Water Resources Report No. 38, University of Texas,
            Austin, Texas (February,  1969).

 3.     Gameson, A. L. H. , Saxon, J. R.  "Field Studies on Effect of Daylight on
            Mortality of Coliform Bacteria," Water Research, 1_, 279-295 (1967).

 4.     Geldreich, E. E. , Clarke,  N. A.  "Bacterial Pollution Indicators in the
            Intestinal Tract of Freshwater Fish," App. Microbiology, L4 (3),
            429-437 (May,  1966).

 5.     Telutchenko,  M.  M., Fodorov, V. D.  "The Interrelation Between Algae
            and Bacteria in Reservoirs,"  Byullete'n Muskovskogo Obshchestva
            Ispytatelei Pirody Otdel Biologicheskii (USSR), 67^ (3), 148-149 (1962),

 6.     Hanes, N. B., Sarles, W.  B., Rohlich, G. A.  "Effects of Temperature
            on Survival of Indicator Bacteria in Water," New England Water Works
            Assn. Jour., 8Qi (1), (March, 1966).

 7.     Geldreich, E. E.  "Detection and Significance of Fecal Coliform Bacteria
            in Stream Pollution Studies," Jour. Water Poll.  Cont. Fed. , 3J7 (12),
            1722-1726 (December,  1965).

 8.     Gallagher, T.  P.,  Spino, D. F. "The Significance of Numbers of Coliform
            Bacteria as an Indicator of Enteric Pathogens,"  Water Research,  2_,
            169-175 (1968).

 9.     Churchill, M. A., Nicholas, W. R. "Effects of Impoundments on Water
            Quality," Jour. San. Engr. Div.  A.S.C.E.  93., SA 6, 73-90 (De
            (December,  1967).

10.     McGrew, S. B., Mallette, M. F.  "Energy of Maintenance of Escherichia
            coli," Jour. Bacteriol., 83, 844-850 (1962).

11.     Guthrie, R. K., Cooper, B. H. , Ferguson, J. K. Allen, H. E.  "Interaction
            Between Escherichia coli and Pseudomonas aeruginosa in Mixed
            Cultures7" Canadian Jour, of Microbiol. , 11,  947-952 (1965).
                                          54

-------
                                                                            55
 12.    Geldreich, E. E. "Fecal Coliform Concepts in Stream Pollution," Water
            and Sewage Works, Ref. No. 1967, R-98-R-110.

 13.    Hellebust, J. A.  "Excretion of Some Organic Compounds by Marine
            Phytoplankton," Limnol. andOceanog.,  10_ (3), 192-206 (1966).

 14.    Ward, C. H., Moyer, J. E. "Ecologic Relationships Between Bacteria
            and Algae in Mass  Culture," Presented at Conf» on Bioregenerative
            Systems, Amer. Inst. Bio.  Sci. and N.A.S.A., Washington, D.C.
            (November, 1966).

 15.    Fogg, G. E. "Extracellular Products," In;  Physiology & Biochemistry
            of Algae, R. A. Lewin,  Ed., Academic Press, New York, N. Y.,
            475-486 (1962).

 16.    Fogg, G. E. "The Importance of Extracellular Products of Algae in the
            Aquatic Environment," U.S.P.H.S.  Pub.  No. 999-WP-25,  34-37
            (1965).

 17.    McLachlan, J., Yentsch, C. S. "Observations of the Growth of Dunaliella
            euchlora in Culture," Biol. Bull., 116, 461-471 (1959).

 18.    Nakamura, H. "Studies  on the ecosystem of Chlorella, " In; Studies on
            Microalgae and Photosynthetic Bacteria,  Univ. Tokyo Press, 197-
            204 (1963).

 19.    Pratt, R., Fong, J.  "Studies on Chlorella yulgaris. II. Further evidence
            that Chlorella cells form a  growth-inhibiting substance," Amer.
            Jour. Botany, _27, 431-436  (1940).

20.    Krauss, R. W. , Thomas, W. H. "The Growth  and Inorganic  Nutrition of
            Scenedesmus obliquus in Mass Culture," Plant Physiol., 29,  205-
            214 (1954).

21.    Levinson, R. A., Tew, R. W. "Studies of Climax Bacterial Populations
            in Continuous Algae Cultures," Tech.  Memorandum No. 191-61-10,
            Aerojet-General Corporation, Azusa, California (1961).

22.    Salmonella Surveillance, Report No. 84, Natl. Comm.  Disease Center,
            U.  S.  Dept.  of H.E.W., Atlanta, Georgia (April 29, 1969).

23.    Gann, J. D., Collier, R. E., Lawrence, C. H.  "Aerobic Bacteriology
            of Waste Stabilization Ponds," Jour. Water Poll.  Cont. Fed. ,
            4£,  185-191  (February,  1968).

24.    Eliassen, R.  "Aftergrowth of Coliforms in Estuarine Water Receiving
            Chlorinated Overflows," Presented at  the Natl. Symposium on
            Estuarine Pollution, A.S.C.E.,  Stanford, California (August,
            1967).

-------
                                                                           56
25.    Ward, C. H., Moyer, J. E., Vela, G. R.  "Studies on Bacteria Associated
           with Chlorella pyrenoidosa TX71105 in Mass Culture," Dev.  in Ind.
           Microbiol., Amer. Inst.  of Bio.  Sciences, Washington, D. C.,  6.,
           213-222 (1968).

26.    Scott, E. G., Bailey, W. R.  Diagonostic Microbiology, TheC. V.
           MosbyCo., St. Louis, Mo.  (1966).

27.    Standard Methods for the Examination of Water and Wastewater, Amer.
           Pub. Health Assn., Amer. Water Works Assn., Water Poll. Cont.
           Fed., 12th Ed. (1965).

28.    Birge, E. R., Judey, C.  "Solar Radiation and Inland Lakes," Trans.
           Wise. Acad. Sci.. 24-27 (1929-1932).

29.    Bolitho, V. N. , "The Economics of Methods Available to Local Authorities
           for the Chemical and Bacterial Improvements  of Purified Sewage
           Effluents," Tour. Proc. Inst. Sew. Purif., Part 3, 216-233 (1965).

30.    Caldwell, D. H. "Sewage Oxidation Ponds Performance, Operation,
           and Design," Sewage Works Jour., 18. (3), 433 (May, 1946).

31.    Coetzee, O. J., Fourie, N. A.  "The Efficiency of Conventional Sewage
           Purification Works, Stabilization Ponds, and Maturation Ponds with
           Respect to the Survival of Pathogenic Bacteria and Indicator Orga-
           nisms, " lpur.J^roc.J^t_.J3^^         Parts, 1-7(1965).

32.    Eck, H.  van "Sewage Stabilization Ponds  - Critical Review," Trans.
           S. Afr. Inst. Civ. Engrs., 9., 137-153 (1958).

33.    Eck, H.  van "Theory of Stabilization Ponds and Its Implication on Their
           Design and Operation," (In:  CSA Specialist Meeting on Water
           Treatment, Pretoria) London, Comm. for Tech. Cooperation in
           Africa South of the Sahara (Publ.  64), 279-295 (1961).

34.    Eck, H. van "The Anaerobic Digestion Pond System," (In:  Biennial
           Conf. of the Institute of Sewage Purification), S.  African Branch,
           Durban, London, Inst. Sew.  Purif. (1965).

35.    Flint, L. H., Moreland, C. F. "Antibiosis in the  Blue-green Algae,"
           Amer. Jour. Botany, 33, 218  (1946).  (Abst.)

36.    Gorham,  P. R., "Toxic Waterblooms of Blue-green Algae," (La:  Trans.
           Third Seminar on Biological Problems in Water Poll., Dept. H.E.W.,
           Pub.  No. 999-WP-25),  37-44(1962).

37.    Lefevre,  M.  "Extracellular Products of Algae," (In:  Algae and Man,
           Ed. by D. F. Jackson), Plenum Press (1964).

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                                                                           57

38.    Marais, Go v. R. "A Rational Theory for the Design of Sewage Stabiliza-
           tion Ponds in Tropical and Subtropical Areas," (In: Symposium on
           Hygiene and Sanitation in Relation to Housing, CCTA/WHO,  Niamey)
           London, Comm.  for Technical Cooperation in Africa South of the
           Sahara (Publ. 84) (1963).

39.    Marais, G. v. R. "New Factors in the Design, Operation, and Performance
           of Waste-Stabilization Ponds," Bull. Wld. Health Org. , .34, 737~
           763 (1966).

40.    Marais, G. v. R. , Shaw, V. A. "A Rational Theory for the Design of
           Sewage Stabilization Ponds in Central and Southern Africa," Civ.
           Engr. S.  Afr. , 3 (11), (1961).

41.    McGarry,  M. G., Bouthillier, P. H. "Survival of S. typhi in Sewage
           Oxidation Ponds," Jour. San. Engr. Div.  Amer.  Soc. Civ. Engr.,
           92_, 33-43 (1966).

42.    Meron, A., Rebhun,  M., Sless, J. B.  "Quality Changes as a Function
           of Detention Time in Wastewater Stabilization Ponds," Jour.  Water
           Poll.  Cont.  Fed.,  37., 1657-1670  (1965).

43.    Neel, J. K. , Hopkins,  G.  H. "Experimental Lagooning of Raw Sewage,"
           Sew.  and Ind. Wastes Jour., 28,  1326 (November, 1956).

44.    Orlob, G. T.  "Viability of Sewage Bacteria in Sea Water,"  Sewage and
           Ind. Wastes Jour., 28.,  1147-1167 (1956).

45.    Oswald, W. J.,  Gotaas, H. B. "Photosynthesis in Sewage Treatment,"
           Jour.  San. Engr. Div. Amer. Soc. Civ. Engr., 81, 687 (May, 1955).

46.    Pratt, Robertson, "Chlorellin, an Antibacterial Substance from Chlorella,"
           Science, i9_, 351-352 (1944).

47.    Prescott, G. W. "Biological Disturbances Resulting  from Algal Popula-
           tions in Standing Water," (In:  The Ecology of Algae, Ed. by C. A.
           Tryon, Jr.,  R. L. Hartman) Pub. No. 2,  Pymatuning Lab. of Field
           Biology., Univ. of  Pittsburgh, 22-37 (1959).

48.    Sidio, A. D.,  Richardt, H., Fugazzoto, P. "First  Domestic Waste Stabiliza-
           tion Pond In Pennsylvania," Public Health Reports, 76., 201-208
           (1961).

49.    Smallhorst, D. F., Walton,  B. N.  "The Design and Application of
           Oxidation Ponds," Public Works Jour., 84 (12), 89 (1953).

50.    Spoehr, H. A., Smith,  J. H. C., Strain, H.  H. , Milner, H.  W.,
           Hardin, G.  J.  "Fatty Acid Antibacterials from  Plants," Carnegie
           Inst.  of Washington,  Publ. No. 586 (1949).

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                                                                           58

51.    Towne, W. W.,  Bartsch, A. F., Davis, W.  H. "Raw Sewage Stabilization
           Ponds in the Dakotas," Sew. and Ind. Wastes Jour.,_29 (4), 377-
           (April, 1957).

52.    Vela, G. R., Guerra,  G. N. "On the Nature of Mixed Cultures of Chlorella
           pyrenoidosa TX7110-5  and Various Bacteria," Jour. Gen. Microbiol.,
           42.,  123-131 (1965).

53.    Vladimirava,  M. G. "Dynamics of the Bacterial Microflora Growth in
           Chlorella Cultures," Mikrobiologiya, 30., 374 (1960).

54.    David, E. M., Wilcomb, M. J., Reid, G. W. "Algal Succession and
            Bacterial Reduction in  Bio-oxidation Ponds," Proc. Okla. Acad.
            Sci., 45_, 220-227 (1965).

55.    Gloyna,  E. F. "Design Considerations as Based on Disease Transmission,"
            Chapter 6, Monograph on Waste Stabilization Ponds, World Health
            Organization (1966).

56.    Gloyna,  E. F. "Low Cost Waste Treatment-Waste Stabilization Ponds,"
            Proceedings, United Nations Conf. on the Application of Science
            and Technology for the Benefit of Less Developed Areas, Geneva,
            Switzerland (1963).

57.    Gloyna,  E. F., Suwannakarn, V. "Efecto de la temperature  en el tratamiento
            de aguas residuales mediante estangues de establization," Boletin
           do la Oficina Sanitaria Panamericana, _56_ (2),  128-139  (1964).

58.    Gloyna,  E. F., Espino de la O., E. "Formal Discussion of  Paper 1-6,"
           Presented at the International Conference on Water Pollution Research,
           Munich, Germany, ^September 5-9,  1966). (Paper deals with work
           accomplished under Grant WP00688-02.)

59.    Hermann, E.  R., Gloyna, E. F.  "Waste Stabilization Ponds, Part III,
           Formulation  of Design Equations," Sewage and Industrial Wastes,
           30, 963-975 (August,  1958).

60.    Malina, J. F., Jr.,  Yousef, Y. A. "The Fate of Coliform Organisms in Waste
           Stabilization Ponds," Jour. Water Poll. Cont. Fed., 36. (11), 1432-
           1442 (1964).

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                          APPENDIX A
  STATISTICS OF ALL LABORATORY AXENIC CULTURE STUDIES

Key to Appendix A tabulated columns:
   N             = number of data points used in computing that
                   particular regression line
      2
   S             = the variance of data points about the mean of
    H
                   all data points
     2
   S             = the variation of data points  about the regression
                   line
      2    2
   S  /S        = the variance ratio which if referenced against
    H   r
                   appropriate standard "F" tables would indicate
                   the statistical validity of the data.
   b             = calculated y-intercept
   k              = the dieoff (-) or growth (+) rate coefficient of
                                        kt
                   the typical C  = Cn 10   formulation
   R              = the multiple correlation coefficient
                              59

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                                                                       60
                             Table. A-1

    Reduction statistics of enteric bacteria species with Anabaena
cylindrica. Series BG-I. Bacteria added to algae when in mid-log growth phase,
    N
 Alcaligenes faecalis
    12    57.966    0.6783
 Enterobacter aerogenes
    12   227^04     0.2110
 Escherichia coli
    12    35.917    0,2882
 Proteus vulgaris
    12    79.048    0,8310
 Pseudomonas aeruginosa
    13    17,007    0.6349
 Serratia marcescens
    14      3.1013  1,7802
                                                             R
                         (8.7213*.8873)   (-.0774-.0192)    0.892

                         (8, 3621* ,4949)   (-.0854*^0107)    0.970

                         (8.0230-.5784)   (-.0397-.0125)    0,837

                         (8.3912* ,9822)   (-. 1000*.0213)    0,919

                         (8.2665*.9368)   (-.0512*.0241)    0.739

                         (6,8402*1.5687)  (-.0366*. 0404)    0,341
                             Table A-2

   Reduction statistics of enteric bacteria species with Anacystis nidulans,
    Series BG-I. Bacteria added to algae when in mid-log growth phase.
          SH2/Sr2    Sr2             b                k
N
 Alcaligenes faecalis
    12    78.809    0,4033
 Enterobacter aerogenes
    12    97.721    0.3406
 Escherichia coli
    12   116,24     0;3905
 Proteus vulgaris
    12   111.76     0.3614
 Pseudomonas aeruginosa
    13    57*109    0.2387
 Serratia marcescens
    14    83.845    0.1375
R
                         (7.9753*.8313)   (-. 1145*. 0260)   0.940

                         (7U7923*.7639)   K1172-.0239)   0.951

                         (8.1602-.6598)   (-.0796-.0137)   0.936
                         (7,618li.6798)   (-.0899-.0161)   0,941

                         (7.8915-.5883)   (-.0614-. 0158)   0.-904

                         (8c3103-u4194)   (-.0480-.0099)   0,923

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                                                                      61
                            Table A-3

 Reduction statistics of enteric bacteria species with Gloeocapsa alpicola.
  Series BG-I. Bacteria added to algae  when in mid-log growth phase.

    N   SH2/Sr2     Sr2              b	k        	R_

Alcaligenes faecal is
   12    36.494    0.9304      (6.5049*1.0184)  (-.0688*.0212)   0,820
Enterobacter aeroqenes
   12    79.796    0.1942      (8.1088 + . 7585)   (-.1356^.0357)   0.964
Escherichia coll
   12    44.764    0.5826      (7.7978±.9192)   (-.0849*.0246)   0.882
Proteus vulgaris
   12     8.3744   1.4614      (8.3445*2,0807)  (-. 1205*.0980)   0.736
Pseudomonas aeruginosa
   13    52.261    0.1064      (7.7185*,5751)   (-. 0484*. 0157)   0.946
Serratia marcescens
   14    20.3386   0.1045      (8.0011*. 7897)   (-.0466*.0301)   0.910
                            Table A-4

  Reduction statistics of enteric bacteria species with Oscillatoria chalybia.
    Series BGI. Bacteria added to algae when in mid-log growth phase.

    N    SH2/Sr2    Sr2              b                k            R
Alcaligenes faecalis
    12    22.511    2.0704     (6.5580*1.6270)  (-.0966-.0386)   0.763
Enterobacter aerogenes
    12    6.1434    1.5995     (6.1868-1.6554)  (-.0637-.0518)   0.551
Escherichia coli
    12    31.303    0.6905     (6.4209-1.2376)  (-. 1255*. 0478)   0.887
Proteus vulgaris
    12    136.60    0.2356     (6.9627-.6353)   (-. 1153*.0199)   0.965
Pseudomonas aeruginosa
    13    64.500    0.4957     (8.4764*.9215)   (-.1149*00288)   0.928
Serratia  marcescens
    14    109,20    0.2419     (7.4993*.5193)   (-.0607*.0108)   0.932

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                                                                      62
                            Table A-5

  Reduction statistics of enteric bacteria  species with Oscillatoria formosa
    Series BGI.  Bacteria added to algae when in mid-log growth phase.
                >    n 2              1_                 L.            D
    N
Alcaligenes faecalis
   12   216.93    0.1511
Enterobacter aeroqenes
   12   14.656    3.7099
Escherichia coli
   12   17.347    2.8252
Proteus vulgaris
   12   12.962    4.7076
Pseudomonas aeruginosa
   13   15.716    2.6409
Serratia  marcescens
   14   65.150    0.4653
                              (8o6823*.5790)   (-. 1546*.0224)   0.982

                              (7.3945*2.0752)  (-.0910±. 0450)   0.677

                              (7.1810-1.8109)  (-.0864-.0393)   0.712

                              (6.5127-2.3376)  (-.0964*. 0507)   0.649

                              (7.1070*1.7509)  (-.0795*.0379)   0.692

                              (7.6482^.7349)   (-.0679-.0159)   0.903
                            Table A-6

 Reduction statistics of enteric bacteria species with Phormidium faveolarum.
     Series BGI. Bacteria added to algae when in mid-log growth phase.
          SH2/Sr2   Sr2             b	k
    N
                                                                  R
                              (6.9144*1.9852)  (-.0880*. 0431)   0.681
Alcaligenes faecalis
   12    14.979   3.3952
Enterobacter aerogenes
   12     6.9355  3.8784      (5.0351*2.1218)   (-.0640*. 0460)   0.498
Escherichia coli                                       ,
   12    9.8227   3.9133      (5.0539*2.3258)   (-.0966-.0599)   0.621
Proteus vulgaris                                       ,
   12    25.151   1.7319      (6.2764-1.9600)   (-. 1782-. 0757)   0.863
Pseudomonas aeruginosa
   13    71.313   0.3654      (7.1779-.9003.)    (-. 1378*. 0348)   0.947
Serratia marcescens
   14    4.9669   1.6954      (6,8908*2.2411)   (-.0999*.1055)   0.623

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                                                                     63
                            Table A-7

   Reduction statistics of bacterial contaminants of Anabaena cylindrica
              during series BG-I with enteric bacteria .
                 I    Q  2              u               v
    N
Escherichia coli
                  0.1714
         45.860    0.0051
Serratia marcescens
   12
        0.7622    0.0224
                                                                  R
Alcaligenes faecalis
   12    0.7611   0.3184      (9.3911-1.3784)  (-.0157±.0526)   0.276
Enterobacter aerogene_s
   12    12.004   0.0249      (9,7528^.3856)   (- .0175*.0147)   0.857
                             (9.6374-2.3863)  (-.0173-. 1320)   0.408
   12   0.6891
Proteus vulqaris
   11   0.8337    0.0605      (9.7131-.4338)   (-.0046-.0118)   0.217
Pseudomonas aeruginosa
   12
                              (9.3210^.1736)   (-.0154-o0066)   0.958
                              (9.6187-. 2641)   (-. 0027-. 0072)   0.203
                            Table A-8

   Reduction statistics of bacterial contaminants of Anacystis nidulans
               during series BG-I with enteric bacteria.

          SH2/Sr2    Sr2              b                k         	
    N
                                                                  R
Alcaligenes faecalis
   12    0.1918   0.3267      (8.4975-1.0079)  (.0051*.0275)    0.060
Enterobacter aerogenes
   12    5.2952   0.0113      (9.7894-.2597)   (-. 0078*.0099)   0.726
Escherichia coli
   12    6.5719   0.0472
Proteus vulgaris
   12    0.8462
                              (9.4214*.3833)    (- ,0114±. 0105)   0.686
                   0.8866     (8.9210-1,6604)  (-.0177-.0453)   00220
 Pseudomonas aeruginosa
   12    2.0035    1,6987     (9.9329-3,1842)  (-,0589-.1216)   0,500
 Serratia marcescens
   12    34.179    0.0150
                              (9.2648-.2163)   (-.0147^.0059)   0.919

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                                                                    64
                            Table A-9

   Reduction statistics of bacterial contaminants of Gloeocapsa alpicola
              during series BG-I with enteric bacteria.
           "   "    Sr2             b                k
    N
                                                                 R
                             (8. 9674-. 2769)   (- .0606- .0075)   0.992
Alcaligenes faecalis
   12    12.7660   0.0290     (7.6995*.4162)   (-.0194^.0159)   0.864
Enterobacter aerogenes
   12    355.73    0,0246
Escherichia coli
   12    20.605    0,3061     (8.2531*1.3517)  (-.0802*. 0516)   0.911
Proteus yulgaris
   12    25.218    0.2025     (8.5118-. 7937)   (-.0462*.0217)   0.894
Pseudomonas aeruginosa
   12    52,609    0.1064
Serratia marcescens
   12    20.338    0.1050     (8.0011*.7897)   K0466*.0301)   0.910
                              (7.7185-.5751)   (- = 0484- .0157)   0,946
                            Table A-10

  Reduction statistics of bacterial contaminants of Oscillatoria chalybia
               during series BG-I with enteric bacteria.
    N     SH2/Sr2   Sr2

Alcaligenes faecalis
   12    43.578   0.1113
Enterobacter aerogenes
   12    44.1414  0,0632
Escherichia coli
   13    Oo5146   2,9367
Proteus yulgaris
   11    9.7113   0,5394
Pseudomonas aeruginosa
   12    6.3348   0,0851
Serratia marcescens
   12    13,609   0.0587
                                                                  R
                              (5.1798-.8152)    (-.0704-.0311)   0.956

                              (5.9133*04432)    (-.0341-.0121)   0.936

                              (5,6901-4,1866)  (-.0393-. 1598)   0.205

                              (6,9309*1.2951)  (-,0468±.0353)   0.764

                              (7n8599±.7l27)    (-.0234-.0272)   0.760

                              (8.8888*05918)    (-.0285-.0226)   0.872

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                                                                   65
                            Table A-11

 Reduction statistics of bacterial contaminants of Oscillatoria formosa
               during series BG-I with enteric bacteria 0

         SH2/Sr2    Sr2             b	k         _
   N
                                                                 R
                             (9,6125±.5447)    (-.0410*.0139)   0.941


                             (9,7453-.7484)    (-.0278-.0191)   0.796
Alcaliqenes faecalis
   12    48.049   0,1016
Enterobacter aeroqenes
   12    11.688   0.1919
Escherichia coli                                       ,
    9478621   0.1967      (9,8661^.7578)    (-«0182±00194)   0.618

Proteus vulgaris                      ,                 ,
	12    7.222    0.0850      (9,6902-.7123)    (-.0250^,0272)   0.783
Pseudomonas aeruqinosa                               +
   H2l7l77   0.2511      (10.0314^.8560)   (-.0428-.0219)   0.876

Serratia marcescens
   1118.190   0.1096      (9.7702^.8088)    (-.0451^.0309)   0.901
                             Table A-12


 Reduction statistics of bacterial contaminants of Phormidium faveolarum
               during series BG-I with enteric bacteria.

                 >.    o 2            K                 k
    N
                                                                  R
Alcaliqenes faecalis                                   ,
	12    0.2333   0.1059      (7,2847-.5559)   (.0029^.0142)    0.072
Enterobacter aeroqenes
   12    ^099   0.2447      (9.0394-.8451)   (-.0368±.0216)   0.843

Escherichia coli                      ,                 ,      x     „„,
	12    il."352   0.0985      (8.7132-.5361)   (-.0196^.0137)   0.791

Proteus vulqaris                                       ,
   IT"  3.2495   0.630.8      (9.0526-1.3569)  (-.0266^.0347)   0.520
Pseudomonas aeruqinosa
   12    27.377   0.0374
Serratia marcescens
   12    23.895    0.1088
                               (8.7549^.3303)   (-.0188^.0084)   0.901


                               (8,7565^.8059)   (-n0515^.0308)   0.923

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                                                                       66
                            Table A-13

 Reduction statistics of enteric bacteria  species with Anabaena cylindrica .
          Series BG-II,  Bacteria and algae inoculated within
                  twenty-four hours of one another.
    N    SH2/Sr2    Sr2              b               k            R
Alcaligenes faecalis
   11    6.459     4,5436     (5,4092*2.0979)  (-.0582-.0419)   0.418
Enterobacter aerogenes
    9    7.704     4.2371     (5.6137*2.2365)  (-.0816-.0557)   0.524
Escherichia coli
    9    16.612    3.8936     (6.9423*2,1439)  (-. 1132-.0534)   0.697
Proteus vulgaris
   12    16.439    3.1431     (5,6887-1,6783)  (-.0687-.0307)   0.622
Pseudomonas aeruginosa
   12    14.83     0.3628     (7.3219-.5702)   (-.0702-.0104)   0.937
Serratia marcescens
   12    18.062    2.0567     (5.8236-1,3576)  (-.0583*.0249)   0.644
                            Table A-14

   Reduction statistics of enteric bacteria  species with Anacystis nidulans.
          Series BG-II.  Bacteria and algae inoculated within
                  twenty-four hours of one another.
    N    SH2/Sr2     Sr2             b                k            R
Alcaligenes faecalis
   12    15.144    0,9024     (6.0191*1.1080)   (-.0640*.0320)   0.716
Enterobacter aerogenes
   12    13.014    1.6865     (5,3492*1,2294)   (-,0448^,0225)   0.565
Escherichia coli
   12    52.405    0.7412     (5.6975*.8150)    (-,0596*. 0149)   0.840
Proteus vulgaris
   10    4.2597    5.0709     (4.4056*2.2207)   (-. 0522*. 0470)   0.347
Pseudomonas aeruginosa
   11    40.969    0,5410     (7.0880*.7078)    (-.0474*.0136)   0.820
Serratia marcescens
   12    6.6982    3.1234     (5,7883*1,6731)   (-.0437-.0306)   0.401

-------
                                                                      67
                            Table A-15

  Reduction statistics of enteric bacteria species with Gloeocapsa alpicola.
          Series BG-II, Bacteria and algae inoculated within
                 twenty-four hours of one another.
    N
           Sr<
Alcaligenes faecalis
   12   23.541   2.7722
Enterbbacter aerogenes
   12   30.543   1.9952
Escherichia coli
   12   27.325   0,7285
Proteus yulgaris
   12   11.356   3.6999
Pseudomonas aeruqinosa
   12   27.164   2.4549
Serratia marcescens
   12   36.312   1.0680
                                                                  R
                    (6.0652-1.6387)  (- .0868-.0328)   0,723

                    (5,5931*1.3902)  (-.0838*. 0278)   0.772

                    (5.0102^.8524)   (-.0494*.0176)   0.773

                    (5.1014-1.9798)  (-.0794*00438)   0.587

                    (6.4011-1.4833)  (-.0781^.0272)   0.731

                    (5.4419-.9783)   (-.0596^.0179)   0.784
                            Table A-16

  Reduction statistics of enteric bacteria species with Oscillatoria chalybia
          Series BG-II.  Bacteria and algae inoculated within
                  twenty-four hours of one another.
    N
SH2/Si
 Alcaligenes faecalis
    12    18o249    2.7641
 Enterobacter aeroqenes
    12    46,006    0.6161
 Escherichia coli
    12    44.993    0.751
 Proteus yulgaris
    12    21.521    1.7036
 Pseudomonas jaeruginosa
    12    41.208    0.4405
 Serratia marcescens
    12    38.386    1.4187
                                                                  R
                     (5,4482*1.6169)  (-.0761^.0327)   0.670

                     (5.4358*.7633)   (-.0571^.0154)   0.836

                     (8.2274-1.3374)  (-.1986^.0631)   0.918

                     (5,5990*1.5143)  (-.1074^.0450)   0.782

                     (6.4460^.7140)   (- ,0614-.0181)   0.855

                     (6.7981-1.2119)  (-.0905-.0272)   0.827

-------
                                                                      68
                            Table A-17

 Reduction statistics of enteric bacteria species with Osciliatoria formosa
         Series BG-II.  Bacteria and algae inoculated within
                 twenty-four hours of one another.
    N    SH2/Sr
2    o_2             h                 k           R
Alcaligenes faecalis
   12    15.581   1.3746      (6.8638-2.8644)   (-.2957-.2187)   0,886
Enterobacter aerogenes
   12    7.3510   0,6556      (6.8156*4.6670)   (-.2218*.5164)   0.880
Escherichia coli
   12    69.975   0=3625      (8,0650-1.0976)   (-.2275-.0640)   0.959
Proteus vulgaris
   12    27.448   0.8883      (7,9273-1.781)    (-.2231*.1002)   0.901
Pseudomonas aeruginosa
   12    27,483   2,2444      (6,7767*1.4182)   (-.0751-.0260)   0.733
Serratia marcescens
   12    60.798   0,9046      (6.5623-.9004)    (-,0709-.0165)   0,859
                            Table A-18

 Reduction statistics of enteric bacteria  species with Phormidium faveolarum.
           Series BG-II.  Bacteria and algae inoculated within
                  twenty-four hours of one another.

    N     SH2/Sr2    Sr2      	b	  	k            R

Alcaligenes faecalis
   12    35.483    1,4550      (5.5216-1,2415)  (-,0880*.0275)   0.816
Enterobacter aerogenes
   12    9.3918    1,8409      (4.7479*1.4742)  (-.0594*.0367)   0.573
Escherichia coli
   12    10.2230   3.2589      (5.1780*1,7090)  (-.0552*.0313)   0.505
Proteus vulgaris
   12    9.5460    1.2614      (5.7131-2.0473)  (-.1567*.1194)   0.761
Pseudomonas aeruginosa
   12    54.309    0.5361      (6.9504-1.3347)  (-.2437*.0778)   0.948
Serratia marcescens
   12    10.628    2.1393      (4.4701*1.3846)  (-.0456-. 0254)   0.515

-------
                                                                   69
                          Table A-19


Reduction statistics of bacterial contaminants of Anabaena cylindrica.
            during series BG-II with enteric bacteria.
  N
            2/c 2
          H /QT
                                                               R
                            (8.9466±,2816)   (-.0187^.0054)   0.881
Alcaliqenes faecalis^
   13    44.545    Oo0424
Enterobacter aeroqenes                ,                +
	12	578129    2.3427      (8,2424- . 6616)    (-.0159-.0128)   0.492

Escherichia coli                      ,                +      .   _ . ._
	12	2To"875~   0.3648      (8.6235^1.0190)   (-.0175-.0258)   0.343

Proteus vulWs    ^^      (g_1277±J-1123)   (..0094±.021S)   0.106

Pseudomonas aeruqinosa                               .  n^n.
	13	T?898    0.2366      (8.6531^,7359)    (-.0198^.0163)   0.545

Serratia marcescens                               noo,+ nic-7\   n  717
	13	ToTill    0.1349     (8,8000^.6195)    (-.0234-.0157)   0.717
                          Table A-20


  Reduction statistics of bacterial contaminants of Anacystis nidulans
             during series BG-II with enteric bacteria.


        SH2/Sr2    Sr2             b	k         _
     N
                                                                   R
                            (8.5258±.2666)   (-.0197-+.0074)   0.890


                            (8.8843±.5258)   (-.0213±.0114)   0.738
                             (8,3519-.7735)   (-.0161^.0168)   0.427
 Escherichia coli
    12    3.7262    Oo3657

 Proteus vulgaris                      +                .  „,...   _ „,.,.
 	12	16.150    0.2533     (8.5266-.6437)    (-.0279^.0140)   0.763

 Pseudomonas aeruqinosa                                ,              n
 	U	o7?013    0,4104     (7.6799^.9494)    (-.0068^.0263)   0.070

 Serratia marcescens^                                   + .....   n OCQ
 	12	267612    0.1054     (8,4857^.4812)    (-.0323-.0133)   0.869

-------
                                                                     70
                            Table A-21

  Reduction statistics of bacterial contaminants of Gloeocapsa alpicola
               during Series BG-II with enteric bacteria.
                21      9
             /c Z    c "              U                1^            1
    N
Alcaligenes faecalis
   13    3.2359    0.2076
Enterobacter aeroqenes
   12    13.108    0.1672
Escherichia coli
   12    5.7870    0.3437
Proteus vulgaris
   12    8.1439    0.1337
Pseudomonas aeruginosa
   12    6.4973    0.0826
Serratia marcescens
   12    16.613    0.1527
            (7.96S8-.6747)    (-.0110-.0130)   0.447

            (8.1383^.6055)    (-.0198-.0117)   0.766

            (8.8736*1.0537)  (-.0271-.0265)   0.658

            (8,5076-.5415)    (-.0139-.0104)   0.671

            (7.9595-.5167)    (-.0141-.0130)   0.684

            (8.2359-.5786)    (-.0213-. 0111)   0.806
                             Table A-22

 Reduction statistics of bacterial contaminants of Oscillatoria chalybia
               during series BG-II with enteric bacteria .

    N    SrT2/S 2    S,2              b                k           R
Alcaligenes faecalis
   12    24.990    0.0192
Enterobacter aerogenes
   12    24.106    0.0310
Escherichia coli
   12    12.224    0.0996
Proteus vulgaris
   12    0.2826    Ool938
Pseudomonas  aeruginosa
   12    0.0174    0.0899
Serratia marcescens
            (7.6573-.2627)    (-.0110-. 0052)   0.893

            (707886*. 3343)    (-.0138^.0066)   0.889
   12   0.7189
0.1208
(8.3854^.5177)   (-.0143-. 0087)   0.753

(7.4938-.83S3)   (-.0037^.0165)   0.086

(7.1715-.5690)   (.0006 -.0112)    0.006

(7.3817-.6596)   (-.0047^.0130)   0.193

-------
                                                                        71
                            Table A-23

 Reduction statistics of bacterial contaminants of Oscillatoria formosa
               during series BG-II with enteric bacteria „

    N    STT2/S .2    S.2              b               k           R
Alcaligenes faecalis                                    .
   12    0,0758   Oo2549      (7.7277*,7207)    (-.0018-.0139)   0.019
Enterobacter aerogenes                                 +
   12    0.4654   0.3258      (7.7450±.8148)    (-.0051-.0158)   0.104
Escherichia coli
   12    3.7691   0.2270      (8.0401-. 6801)    (-.0120-.0132)   0.485
Proteus vulqaris
   12    36.3346  0.0251
Pseudomonas aeruginosa
         (8.0503-.2259)    (-.0124-.0044)   0.901
   12    1.5084    0.1332     (7.7167-.5209)    (- ,0058- ,0101)   0.274
 Serratia marcescens
   12    1.1490    1.4257     (7.8396-.9224)    (-.0129±,0352)   0.365
                             Table A-24

 Reduction statistics of bacterial contaminants of Phormidium faveblarum
               during series BG-II with enteric bacteria.
    N
Sr'
                                                                  R
 Alcaligenes faecalis
   12    3.8100    0.1202     (7.7007-2.0520)  (-,0195±,0630)    0.792
 Enterobacter aerogenes
   12    7,2137    0,1341     (7,8364-.9043)   (-.0174-.0189)    0.783
 Escherichia coli                                       +
   12    10.6154   0.2067     (8.1078-1.1228)  (-.0262-.0235)    0.841
 Proteus vulgaris                                       ,
   12    2.8200    0,2284     (7.7159*1.1805)  (- .0142-. 0247)    0.585
 Pseudomonas aeruginosa
   12    2.6126    0.0269     (6,2282-. 4053)   (.0047^,0085)    0.566
 Serratia marcescens                   ,
   12    2.8029    1.2669     (7.4335-6.6603)  (-.0542^.2044)    0.737

-------
                                                                       72
                           Table A-25


     Growth statistics of bacteria found in axenic algae cultures
                    Series BG-III.  Controls „
N SH2/Sr2 Sr2
Anabaena cyllndrica
b

k R
i nccn+ r\coi\ n 47R
                 5.8969      (3.5555±3.5177)   (.0495^0669)    0.383


                             (1.8642±1.7482)   (.0592^.0333)    0.783
Oscillatoria chalybia                                  +
	12	670545   2,3982      (3 = 9318*2.2433)  (. 0493-. 0427)    0.602

Oscillatoria formosa                   .                .
	12	37o"423   3.4652      (4 ,4801-2 .6966)  (. 0420-.0513)    0.432

Phormidium faveolarum                                ,
	475869   2.7219      (4.1262-2.3899)  (.0457^.0455)    0.534
  12
                            Table A-26
Growth statistics of axenic culture of Anabaena cylindrica with enteric
           bacteria during series BG-Irun,  Series EG-IV,
                Results based on mg/1 dry weight 0
   N
                                              (.0117±.0099)    0.61!


                             (1.7229^.4403)   (.0107±.0079)    0.683


                  0.1098     (1.8928-+.7893)   (.0043-^0139)    0.098


                  0.1148     (1.4919-+.8073)   (.0114-^0143)    0.421


                             (1.2489-^5738)   (.0155±%0101)    0.725
 Serratia marcescens
      --
   ratia marcescens.                   ,               +  nnnn.    . „...
   U -- IO66    0.0493      (1.2862-.5288)   (.0152-. 0093)    0.751

-------
                                                                       73
                            Table A-27

Growth statistics of axenic culture of Anacystis nidulans with enteric
           bacteria during series BG-Irun,  Series BG-IV,
                 Results  based on mg/1 dry weight„
    N
O 2/0
bH /br
                                                                 R
Alcaligenes faecalis
   11   207980   0.1230
Enterobacter aerogene.s
   11   5.5746   0.0575
Escherichia coli
   11   67,451   0.0065
Proteus vulgaris
   11   2.7309   0.0389
Pseudomonas aeruginosa
   11   1.5814   Ool693
Serratia marcescens                                  +
   11~~~ 6.3484   0.0513      (1.3299^.5398)   (.0113-.0095)    0.613
                     (1.4449-.8355)   (.0116^.0148)    0.411

                     (1.1917-.5714)   (,0112*.0101)    0,582

                     (1.602-U1919)    (.0131-.0034)    0.944

                     (1.5815-.4699)   (.0064-^0083)    0,406

                     (1.3273-.9802)   (. 0102-, 0173)    0,283
                            Table A-28

 Growth statistics of axenic culture of Gloeocapsa alpicola with enteric
            bacteria during series BG-Irun, Series BG-IV*
                 Results based on mg/1 dry weight.
                     c 2             K               V
    N
 «  2/0 2
 SH /sr
 Alcaligenes faecalis
   11    1.9229    0,0928
 Enterobacter aerogenes
   11    4o2808    0.0297
 Escherichia coli
   11    5.7088    0,0326
 Proteus vulgaris
   11    0.6004    Oc0673
 Pseudomona s aeruginosa
   11    4.3449    0<0140
 Serratia marcescens
   11    17o924    0.0203
                     (1U6702-.72S7)    (00083-0 0128)
                     (1.9153-.4106)

                     (1.7957-.4299)
(.0070±,0072)

(00085-o0076)
                     (2.1234-.6180)   (.0039-.0109)

                     (2,0407-U2821)   (.0049*^0050)

                     (1.5473-.3399   (.0119^,0060)
                   R
Oo324

0.517

0«588

0,130

0,521

0.817

-------
                                                                      74
                            Table A-29

Growth statistics of axenic culture of Oscillatoria chalybia with enteric
           bacteria during series BG-Irun.  Series BG-IY.
                 Results based on mg/1 dry weight.

    N    SH2/Sr2    Sr2             b                k           R
Alcaligenes faecalis
   11    8.9103   0.0203      (1,5632-.3391)    (,0084-.0059)    0.690
Enterobacter aeroqenes
   11    8.5231   0.0134      (1,6601-.2759)    (.0067^.0048)    0.681
Escherichia coli
   11    0.7271   0.0860      (1.9015-.6988)    (.0049-.0123)    0.154
Proteus vulgaris
   11    26.7943  0.0343      (1.7519-.4414)    (.0189-.0078)    0,870
Pseudomonas aeruqinosa
   11    10.575   0.0580      (102489-.5738)    (.0155^.0101)    0.725
Serratia marcescens
   11    12.066   0.0493      (1.2862-.5288)    (.0152-.0093)    0.751
                            Table A-30

 Growth statistics of axenic culture of Oscillatoria formosa with enteric
           bacteria during series BG-Irun.  Series BG-IV.
                 Results based on mg/1 dry weight.
         Nq  2 /q 2     o "              K                 V          R
         OTT  / O_     O_               U                 JS.          I\
Alcaligenes faecalis
   12    12.215   0.1702      (.6819^.9829)     (,0285±.0174)    0.753
Enterobacter aerogenes
   11    22.734   0.0742      (1.0015-.6489)    (.0256-.0115)    0.850
Escherichia coli                                      +
   13    9.3189   0.1202      (1.1998±.8261)    (.0209-.0146)    0.699
Proteus vulgaris
   12    2.9976   0.2196      (1.3486-1.1164)   (.0160-.0197)    0.428
Pseudomonas aeruginosa
   11    1.4971   0.1744      (1.5118-.9948)    (.0101*.0176)    0.272
Serratia marcescens
   11    3.3157   0.1967      (1,3871*1.0566)   (.0159-.0187)    0.453

-------
                                                                          75
                             Table A-31
Growth statistics of axenic culture of Phormidium faveolarum with enteric
bacteria during series BG-Irun, Series BG-IV,
Results based on mg/1 dry weight ,
M q 2/0 2 o 2 , k
JM OTT /b_ Of D Jv
Alcaligenes faecalis
11 0.0620 0.0763
Enterobacter aerogenes
12 0.0144 0.0504
Escherichia coli
12 0.4124 0=0444
Proteus vulgaris
12 0.4748 0.1242
Pseudomonas aeruginosa
12 0.1167 0.0785
Serratia marcescens
12 1.1185 0.0804
Reduction statistics
contaminant
N SH2/Sr2 Sr2
Alcaligenes faecalis
12 11.847 1.3542
Enterobacter aerogenes
12 61.275 2.4412
Escherichia coli
12 15.235 0.2289
Proteus vulgaris
12 115.08 0.4806
Pseudomonas aeruginosa
12 28.100 1,2490
Serratia marcescens
12 55.697 0.427
(2.1178-.6583) (.00131.0116)
(2.0452-.5349) (. 0005- , 0094)
(2.16461.5023) (-.00271.0088)
(1.64431.8396) (.0048-. 0148)
(2.00891.6676) (- .0019*. 0118)
(2.3023^6755) (-.0059-.0119)
Table A- 3 2
of enteric bacteria species with algal
Brevibacterium, Series BG-V.
b k
(6.7687-1.5672) (- .0513- .0300)
(8.30111.6642) (-.04941=0127)
(8.43661.6432) (-.07551.0123)
(8.46801.9319) (-.0951±.0178)
(7.6973*1.7243) (-. 1011-.0407)
(8. 6455-. 8787) (-.06241.0168)
R
0.015
0.004
0,093
0.106
0.028
0.218
R
0.703
0.924
0.968
0.958
0.875
0.918

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                                                                   76
                         Table A-33

     Reduction statistics of enteric bacteria species with algal
      contaminant, Flaveobacterium , Series BG-V.
 N
        H
            2/q 2
            ./sr
                                                              R
                           (8.1993-2,4757)  (-. 1437-.0945)   0,908
Alcaligenes faecalis
   12    19.699   1.0269
Enterobacter aerogenes
   12    188.33   0.0543      (8.0086*1.3435)  (-.1616*.0743)   0.995
Escherichia coli
   12    21.881   1.4051      (8.1903*1.8289)  (-.0947*.0431)   0.845
Proteus vulgaris
   12    136.43   0.3321      (10.0665*1,0505) (-. 1520*.0306)   0.978
Pseudomonas aeruginosa
   12    22.289   0.9558
Serratla marcescens
   12    16.282   1.6677      (6.5629*1.7360)  (-.0666*.0333)   0.765
                           (7.6614*1,7822)  (-. 1042-.0519)    0.881
                          Table A-34

Reduction statistics of single species of enteric bacteria in presence
of mixed cultures of six species of blue-green algae. Series BG-VIII,

                  O 2              1-                \r
 N
         q  2/q 2
         SH /sr
R
                           (707778±7.0397)  (-.2463-.3S95)   0.941
Alcaligenes faecalis
   13    15.939   1.4918
Enterobacter aerogenes
   12    6.2346   3.5258      (8,1472- 10.8224) (-,2368-.5988)   0.862
Escherichia coli
   13    0.3556   2.9060      (7.0455-7.1646)   (-.1666-,1590)   0U824
Proteus vulgaris
   13    5.4117   4.1432
Pseudomonas aeruginosa
   12    10.783   2.7206      (7.0364-4.0296)   (-.1730-.1538)   0.843
Serratia marcescens
   12    4.2473   5.0527      (6.4926-5.4915)   (-»1479*.2096)   0.679
                           (8,1208-11.7319)  (-.2392^.6491)   0,844

-------
                                                                       77
                            Table A-35

   Reduction statistics of mixed enteric bacteria in presence of mixed
      cultures of six species of blue-green algae.  Series BG-IX.

    N   SH2/Sr2    Sr2      	b	  	k	   	R_
Alcaliqenes faecalis
   11    14.056    1,8856     (6.7616^.9146)   (-.2600-.4379)   0.933
Enterobacter aeroqenes                                 ,
   11    5.9160    4.9779     (6.8051*12.8595)  (-.2741-.7115)   0.855
Escherichia coli                      ,
   11    0,0786    19.409     (4.1152-19.6689)  (-.1081*2.4333)  0.073
Proteus vulgaris                                       ,
   11    4.3410    5.6157     (6 .2648±12 .6453)  (-. 1632-.4947)   0.813
Pseudomonas aeruqinosa
   11    13.145    1.7591     (6.9496±3.2402)   (-. 1536*. 1237)   0.868
Serratia marcescens
   11    36.931    0.5183     (7.0223^1.7588)   (-.1397^.0671)   0.948
Total* of all  6 enterics
   11    20.528    1.1271     (7.5912*2.5936)   (-.1536^.0990)   0.911
 *  Data for the total number of enteric bacteria, not sum of individual
   statistical results for each species.

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                                                                       78
                            Table A-36

Reduction statistics of enteric bacteria species with Ankistrodesmus braunii,
      Series G-I.  Bacteria added to algae when in mid-log phase,

    N     SH2/Sr2     Sr2              b               k           R
Alcaligenes faecalis
   13    59.850   0,45717    (7.0994^9669)    (-.0701^.0193)   0.937
Enterobacter aerogenes
   14    89.272   0.36307    (8.2215-.8617)    (-.0764^0172)   0.957
Escherichia coli
   14    7.1998   1.0295      (6.7241-1.4509)   (-.0365±.0290)   0.643
Proteus vulgaris
   11    38.053   0.35906    (6.9891-1.0566)   (- .0756^.0288)   0.927
Pseudomonas aeruginosa
   12    42.717   0.29243    (7.9607-1.3211)   (-.1129-.0504)   0U955
Serratia marcescens
   12    11.093   0.82891    (9.1086-1.6055)   (-.0620^0438)   0,787
                            Table A-37

 Reduction statistics of enteric bacteria species with Chlorella pyrenoidosa
      Series G-I.  Bacteria added to algae when in mid-log phase.
    N    SH2/Sr2     Sr2
R
Alcaligenes faecalis
   13   447.65   ,05507      (8,1764^.5733)   (-.1586-.0219)   0.995
Enterobacter aerogenes
   14   9,3163   2.6364      (7.7223-2.8633)  (-.1013-.0781)   0.756
Escherichia coli
   14   19.113   1.1338      (6.6677*1.5227)  (-.0624t.0305)   0.827
Proteus vulgaris
   11   23.078   1.3761      (8,2918-2.8659)  (-.1800-.1094)   0.920
Pseudomonas aeruginosa
   12   9.1331   2.5412      (8,0134-2.8111)  (-. 0985±.'O767)   0,753
Serratia marcescens
   12   17.501   0.9995      (7.0495-1,7629)  (-.0855±.0481)   0.854

-------
                                                                        79
                            Table A-38

  Reduction statistics of enteric bacteria  species with Chlorella vulgaris.
      Series G-I.  Bacteria added to algae when in mid-log phase.
    N
Alcaligenes faecali_s
   12    8.5477    1.8059
Enterobacter aeroqenes
   12    6.7731    3ol823
Escherichia coli
   12    4,2474    2,8177
Proteus vulgaris
   12    6.2347    2.0976
Pseudomona_s aeruginosa
   12    19.549    1.4598
Serratia marcescens
   12    I2o080    1.8887
                                                                R
                           (7.1179*3.2831)  (-. 1255*. 1253)   0.810

                           (7,1567-3.1458)  (-.0949*0.0858) 0 = 693

                           (6.5618*2.4005)  (-.0464*0.0480) 0.515

                           (8.1411*8.3476)  (-. 1826*. 4619)   0.862

                           (8,1344-2.1307)  (-. 1092*. 0581)   0.867

                           (7.9809-3.0490)  (-.0651*. 0547)    0.858
                           Table A-39

Reduction statistics of enteric bacteria  species with Scenedesmus^bliguus..
    Series G-I.  Bacteria added to algae when in mid-log phase,
              >     o 2             K                k
     N
 Alcaligenes faecalis
    12    7.1587   1.6250
 Enterobacter aeroqenes
    12    26,533   0.6903
 Escherichia^ coli
    12    40.527   0.2004
 Proteus vulqarls
 Serratia marcescens
    12    41.964    0.5409
                                                                  R
                            (6.1286-1,8230)  (-.0458*. 0365)   0.642

                            (6,9105*1.1881)  (-.0574*.0238)   0.869

                            (7,4914*0.7894)  (-.0583*.0215)   0.931

                            (6,9057*1.8545)  (-. 0891*. 0506)   0.851

                            (7.9135*1,3072)  (-.0777-;0357)   0.898

                            (8,8431*1.2969)  (-,0974*.0354)   0.933

-------
                                                                        80
                            Table A-40

 Reduction statistics of enteric bacteria species with Ankistrodesmus bra unit.
Series G-II. Bacteria and algae inoculated within twenty-four hours of one another

    N    SH2/Sr2    Sr2             b                k
                                                                 R
                              (7.8609*8.9976)   (-.0542*. 1598)   0.821
Alcaligenes faecalis
   12    154.98   0.19994     (8.7434-2.4481)   (-.0857^.0435)   0,994
Enterobacter aeroqenes
   12171603   1.5360     (8.5471±6.7856)   (-.0801*.1205)   0=946
Escherichia coli
   12    4.5853   2,7007
Proteus vulgaris
   12~  1.8897   12.398     (7.2077*19,278)   (-.0745*.3424)   0.654
Pseudomonas aeruqinosa
   12    1765.9   0,01860    (8.9704*.8609)    (-.1977^.0297)   0.999
Serratia marcescens
   12~ 1891.1   0.01366    (9.7349-.7378)    (-. 1753*.0254)   0.999
                             Table A-41

   Reduction statistics of enteric bacteria species with Chlorella pyrenoidosa.
Series G-II. Bacteria and algae inoculated within twenty-four hours of one another.
     N
          o 2/q 2    g 2
          SH /Sr     br
Alcaligenes faecalis
    12    24.159    0.9386
Enterobacter aeroqenes
    12    2899,2    0.0046
Escherichia coli
    12    12.115    2.0249
Proteus vulgaris
    12    69.343    0.1855
Pseudomonas aeruginosa
    12    10.876    1,2791
                                                                 R
                              (7.9536*5.3042)   (-.0743*.0942)   00960

                              (9,2054^.4299)    (-.1265^.0148)   0.999

                              (7.7306-7.7908)   (-. 0763*. 1384)   0,924

                              (7.0642*2.3582)   (-,0552-.0419)   0.986

                              (8.0599*6.1921)   (-.0574*. 1100)   0.916
 Serratia marcescens                                   ,
    12    19.603    0.6550     (8.2736*4.4309)  (-.0552-.0787)    0.951

-------
                                                                       81
                            Table A-42


Reduction statistics of enteric bacteria species with Chlorella vulgaris.  Series
 G-II.  Bacteria and algae inoculated within twenty-four hours of one anotter,

   _N_   SH2/Sr2     Sr2	b	k         _R	

Alcaligenes faecalis
   12    2125,2    0,00398     (5,9987^.3983)   (-. 1003^.0137)   0,999
Enterobacter aerogenes                                 ,
   1221?6.9    0.00505     (7,5548^.4487)   (-.1138-.0155)   0,999

Escherichia cpli                                       +
   12    470005    1,7486     (5.6424^7.2399)  (-. 0407-. 1286)   0.800

Proteus vulgaris                      .                 ,
   12~  2362.9    0.0065     (8.1123^.5091)   (-.1352^.0176)   0,999
Pseudomonas aeruginosa                               +
   124933,7    Oo0062     (7,4898-.4954)   (-.1901-.0171)   0,999

Serratia marcescens                                   ,           nnn
	12     1781,4    0,0046     (6.6976^,4292)   (-,0989±a0148)   0,999
                             Table A-43

 Reduction statistics of enteric bacteria species with Scenedesmus obliguus .
 Series G-II. Bacteria and algae inoculated within twenty-four hours of one
 another.
     N   SH2/Sr2    S2               b __ k         _R _
 Alcaligenes, faecalis
 - 12    847.23    0.02134     (7 ,4529- . 7997)   (- ,0655±. 0142)   0.998
 Enterobacter aerogene^                                 ,
 - 12 - sTil.5    0.00448     (8,3051- ,3663)   (-.0792^,0065)   0,999

 Escherichia. coli                       ,                +.„,.„
 - 12    2?,286    0.42066     (6.7184^3,5509)  (-.054^.0631)   0,967

 Proteus vulgaris                                       +
 - 12 -- 182T75    0.00183     (6 n4763^.2699)   (-.0629^,0093)   0,999

 Pseudomonas aeruginosa                                ,
 - 12    2TIl69    4,3286     (6.6961-11,3908) (- ,0466-, 2023)   0,679

 Serratia marcescens                   ,                 ,
 - U -- T6209    1.3397     (7,5169-6,3371)  (-,0492^.1126)   0.884

-------
                                                                      82
                            Table A-44

  Reduction statistics of single species of enteric bacteria in presence
   of mixed cultures of four species of green algae. Series G-VIII.

                    R 2              h                k           R
   N
         SH2/S_2
                             (6.8582-2,0250)  (-.1280^.0773)   0.921
Alcaligenes faecalis                                    ,
   12    47.994   0.5460      (7.5188-1.8052)  (-.1635-.0689)   0.959
Enterobacter aerogenes
   12    145.79   0.1437      (6.6479*.9259)   (-.1462*.0353)   0.986
Escherichia coli
   12    23.382   0.6871
Proteus vulgaris
   12    7.9498   1.8035      (7.3760-7.7403)  (-.1912*.4282)   0.888
Pseudomonas aeruginosa
   12    71.674   0.4158      (8.1735*1.5754)  (-.1744^.0601)   0.973
Serratia marcescens
   12    59.165   0.3693      (7,2299*1.4847)  (-.1493*.0567)   0.967
                            Table A-45

Reduction statistics of mixed enteric bacteria in presence of mixed cultures
            of four species of green algae.  Series G-K.

    N    SH2/Sr2     Sr2            b                 k
                                                                 R
                             (6.6735*6.2179)  (-. 1176*.3440)   0.823
Alcaligenes faecalis
   11    4.6588    1.1638
Enterobacter aerogenes
   13    2.2508    0.7552     (6.9674-5.0089)  (-.2082^.2771)   0.957
Escherichia coli
   13    17.089    1.1520     (7.3603-2.6222)  (-.1417^.1001)   0.895
Proteus vulgaris
   12    3.4883    3.4136
Pseudomonas aeruginosa
   12    11.588    1.8844     (7.4373-3.3536)  (-.1493*.1280)   0.853
Serratia marcescens
   12    27.099    0.9017     (7.6250*2.3198)  (-. 1579-.0885)   0.931
Total enteric count (all six above)
   12    21.552    1.0055     (8.1321*2.4497)  (-. 1487-.0935)   0.915
                             (6,8254*10.650)  (-. 1743*. 5893)   0,777

-------
                                                                     83
                             Table A-46

Reduction statistics of enteric bacteria species in algal growth medium.
                             Series VI.
    N
sH2/sr2
                                                                 R
Alcaligenes faecalis
   12    2.2010    2o7828
Enterobacter aeroqenes
   12    0.3045    3.6089
Escherichia coli
   12    2.1764    2.4862
Proteus vulqaris                                      +
   12~  0.6976    3.7817      (6,1353-1.4299)  (-.0149-.0325)   0,065
Pseudomonas aeruginosa
   12    1.1722    1.7682
Serratia marcescens
   120.3976    2.880      (7.1737-1.2479)  (-.0098^,0283)   00038
                    (6.9431-1,2267)  (-00228^.0279)   0.180

                    (6.0233-1.3969)  (-.0097^.0317)   0.029

                    (6.3741*1.1595)  (-.0214^.0263)   0.179
                     (6.9922^.9778)   (-.0133^.0222)   0.105

-------
                                                                      84
                               Table A-47


Reduction statistics of enteric bacteria species in filtrate from Anabaena
cvlindrica at mid-log growth phase ,  Series VII.
    N   SH2/Sr2
                                                                 R
Alcaliqenes faecalis                  .                 + nr.^n\    „ ncc
	11	6.4853   0,2025     (7.7104-2.4823)  (-.0230-.0570)    0.866

Enterobacter aerogenes                                 +
     12    5~,7437   0.4313     (7,4657-3.6224)  (-.0316-. 0832)    0.852


EscherichiacglL   ^^     (8,0062±2,5035)  (-.0164^.0575)    0.765



                   0.6346     (7.4696±4.3939)  (-.0253^.1009)    0.715


                              (7. 7903±2 .3862)  <-.0167±.0548)    0.788
 Serratia marcescens                  .                 + nAn..   . ....
 	12	2.2672  0.1520     (7.8025-2.1506)  (-.0118-,0494)   00694



                                Table A-48


 Reduction statistics of enteric bacteria species in filtrate from Anacystis
 nidulans at mid-log growth phase.  Series VII.
     N    SR2/Sr2
                                                                 R
Alcaligenes faecalis                  .                +  n/.n^   n  AOO
- 12 - H^72    0,2918      (7.8427-2.9796)   (-.0375-. 0684)   0.923

Enterobacter aerogenes                +                +  rt.nrx   n  Ooo
- 12 - 5T.426    0.1023      (7.8034-1.7639)   (-.0469-. 0405)   0.982


                              (7,5976-2.8743)   (-.0212-. 0660)   0.805


                              (7.3661-4.6137)   (-.0525-. 1060)   0.907

Pseudomonsa aeruginosa               +             „„,,.+  oo-,o^   n  Q-JQ
- 12 - 5T2270   0.4748      (8,0166-3,8006)   (-.0316-. 0873)   0.839

Serratia marcescens                   ,                 +  , -„..    n  _cyl
- 12 -- 3,0764   0.7320      (7,4349^4.7190)   (-.0301-. 1084)    0.754
  ro eus vu aaris

-------
                                                                   85
                               Table A-49

Reduction statistics of enteric bacteria species in filtrate from Gloeocapsa
alpicola at mid-log growth phase.  Series VII.
    N
Alcaliqenes faecalis
     12    3.2476   0.1193
Escherichia coli
    12    253772  0.0042
                                                                 R
                              (8.5132-1.9048)  (-, 0395-. 0437)   0.970
Enterobacter aeroqenes                ,                +
     12    fOie.S   0,0087     (9.2218-  .5138)   (-.0596-. 0118)   0.999
                                     ,                +
                              (8*6674-  .3579)   (-.0656-. 0082)   0,999
Proteus vulgaris                      .                 +
     12  93.455    0.0594     (9.1244-1.3448)   (-.0473-, 0309)   0.989

Pseudomonsa aeruqinosa              ,                 +
     14   773096   0.1320     (8. 6017-2 .0040)   (-.0197-. 0460)   0.879

Serratia marcescens                  ,                 +
     12   0.3661   2.9428     (7.7528-9.4620)   (-.0208-. 2174)   0.268
                                Table A-50

Reduction statistics of enteric bacteria species in filtrate from Nostoc
muscorum at mid-log growth phase.  Series  VII.
    N
          SH2/Sr2
                                                                 R
Alcaliqenes faecalis                   ,                +
	14	672929  2.9351      (7,5992-9.4495)  (-.0862-. 2171)   0.863

Enterobacter aeroqenes                .                +
	TI	2T.8502  0..8679      (8.2287-5 = 1385)  (-. 1021-. 1180)   0.967
                               (8.0406-5.1242)  (-.0881-. 1177)   0.957


                               (8.2417-  .3411)  (-.1021-.0078)   0,999
Escherichia coli
     12   22.339    0,8631

Proteus vulgaris
     12     6768.7  0,0038

Pseudomonsa aeruqinosa               ,                +
	12	879025  1.1393     (7.5259-5,8874)  (-.0639-. 1352)    0,899

Serratia marcescens                   ,                +
	IF 15.896    Oc5653     (7.6208-4.1472)  (-.602 -,0953)    0.941

-------
                                                                      86
                               Table A-51

Reduction statistics of enteric bacteria species in filtrate from Oscillatoria
chalybia  at mid-log growth phase»  Series VII.

    N    SH2/Sr2    Sr2              b	k	R	
Alcaliqenes faecalis                   ,                 +
- 12    18.221  1.2523      (8.0115-6.4142)   (-.0996-. 1473)   0.948

Enterobacter aerogenes                ,                 +
     12    19,231  1.1985      (7.4310-6.0384)   (-.0963-. 1387)   0.951

Escherichia coli                      .                 +     4     nnn
- 12 - '8.7375 2.9108      (7.7619^9.4103)   (-.1012-. 2162)   0.897

Proteus vulgaris                      .                 +
- 12    13.628  1.6409      (7.2278*7.0653)   (-.0949-. 1623)   0.932

Pseudomonsa aeruginosa              ,                 +
- 12 - 54.986  0.3240      (7.3250*3.1396)   (0.0847-.0721)   0.982

Serratia marcescens                   .                 +
- 12 -- 5.2723 3c0540      (7. 7516±9.6390)   (-.0805-. 2214)   0.840



                               Table A-52

Reduction statistics of enteric bacteria species in filtrate from Oscillatoria
formosa at mid-log growth phase.  Series VII.

             22      2                               k          R
     N    S   /Sr     Sr
           ji    r      r
Alcaligenes faecalis                  .                 +
	12    2.3677   6.0714     (7.1292-13.5907) (-.0761-.3122)    0.703

Enterobacter aeroqenes                ,                 +
	12    7.9584   1.6716     (8.1111-  7.1312) (-.0732-. 1638)    0.888

Escherichia coli                      .                 +
     12    0^880   0.5797     (3.1487*  4.1997) (  .0136-.0965)    0.441

Proteus vulqaris                      .                 +
     12"   5.0901   2.2407     (7.5433-  8.2564) (-.0678-. 1897)    0.836

Pseudomonsa aeruginosa              ,                 +
     12   247278    0.3300     (8.4717-  3.1687) (-.0568-.0728)    0.960

Serratia marcescens                  .                 +
     12    4.2481   2.6330     (8.1498*  8.9501) (-.0671-.2056)    0.809

-------
                                                                      87
                               Table A-53


Reduction statistics of enteric bacteria species in filtrate from Phormidium

fayeolanum at mid-log growth phase.  Series VII.


    N    STT2/S_2    S_2              b                k           R
Alcaliqenes faecalis                  +                +
	12	679894   1.7256     (7.4942-7.2456)  (-. 0697-. 1664)   0.875


Enterobacter aerogenes                ,                 + ,,  .   _ ....
	14	rT.285    1.2290     (8.1289-6.1147)  (-.0841-. 1405)   0.934


Escherichia^c|_i^   4ol571     (7.7636-11.2459) (-.0646-. 2584)   0.714



                   0.3666     (7.7698-2.2297)  (-.0643^.0767)   0.965
 roteus
     11  2£

Pseudomonsa aeruqinosa              +            „„„„+ , r/ir,\   n ooo
	13	872261  1.4944     (7.6431-6.7427)  (-.0704-. 1549)   0.892
                                               (..08ll±.1332)   0.936
                                Table A-5 4
 Reduction statistics of enteric bacteria species in filtrate from Ankistrodesmus

 braunii at mid-log growth phase.  Series VII.


     N     SH2/Sr2    Sr2              b	k	R	



                               (7.7835-12.1020) (-.0769-.2780)   0.753



                                                (-.0965-.1696)   0.928
 Escherichia ss&^  ^^     (?^^t ^gm}  (._0520i_0090)    0.999



 Proteus vulqaris s   ^^     (7.3531±2.5691)  (-.0904±.0590)    0.989



                                                (..OB90±.0751)    0.982


                                                ,..0558±. 1196)    0.897

-------
                                                                       88
                            Table A-55
Reduction statistics of enteric bacteria  species in filtrate from Chlorella
pyrenoidosa at mid-log growth phase.  Series VII.

   ^J    SH2/Sr2    Sr2              b                k         __R_
Alcaligenes faecalis
   12   5.4223    3.9217      (7.4986-10,9228) (-.0925^.2509)   0.844
Enterobacter aeroqenes
   12   6.9282    2,5946      (7,5341*8.8844)  (-.0851-.2041)   0.874
Escherichia coli                                        ,
   12   1.8148    6.8664      (7.2231*14,4531) (-. 0708-.3320)   0.645
Proteus vulgaris
   12   5,1004    3.3545      (7,3782*10.1021)  (-.0830-.2321)   0.836
Pseudomonas aeruqinosa                                ,
   12   0.8458    8,8804      (7,3886-16.4367) (-.0550-.3776)   0.458
Serratia  marcescens
   12   1.4244    8.2050      (7.5455*15.7993) (-.0686-.3630)   0.587
                            Table A-56

Reduction statistics of enteric bacteria species in filtrate from Chlorella
yulgaris at mid-log growth phase.  Series VII.

    N    S  2/S 2     S 2              b                k           R
          rl   r      i   		  	,	_—   __
Alcaligenes faecalis
   14    8.1485   2.2109      (7,0826*8.2012)   (-.0852*.1884)   0.891
Enterobacter aeroqenes
   14    11.8899  0,8985      (5.9278*5.2283)   (-.0656-. 1201)   0.922
Escherichia coli                                       ,
   14    6,2986   1.2075      (7,0093-6.0610)   (r .0553-. 1392)   0.863
Proteus vulgaris                                       ,
   14    14.888   0.9550      (6.5244*5.3902)   (-.0757-. 1238)   0.937
Pseudomonas aeruqinosa
   14    3.6679   3,1607      (7,2067*9.8060)   (-.0683*.2253)   0.786
Serratia marcescens
   14    2.6636   3.8659      (6.5441*10.8448)  (-.0644^.2491)   0.727

-------
                                                                        89
                            Table A-57

Reduction statistics of enteric bacteria species in filtrate from Scenedesmus
obliquus at mid-log growth phase.  Series VII.
                !     c 2             v,                k
   N
                                                                R
                             (8.8573-.9313)   K0324±.0214)   0.989
Alcaliqenes faecalis
   14    91.4609   0.0285
Enterobacter aerogenes                                 ,
   14F09.62    0.0585      (8.9597-1.3346)  (-.0508^.0307)   0.991
Escherichia coli                                       ,
   1457.6465   0.0773      (8.4025^1.5335)  (-.0401^.0352)   0.981
Proteus vulgaris                                       ,
   14~  1.3987    0.4076      (8.2736*3.5216)  (-.0151^.0809)   0.583
Pseudomonas aeruginosa
   14    16.5995   0.4526
Serratia marcescens
   14    5.1187    5.1345
                             (8.0305-3.7108)  (- .0550- . 0852)   0.943

                             (8.3673*3.9523)  (-.0325^.0908)   0.836
                             Table A-5 8

Reduction statistics of pathogenic bacteria species with Anabaena cylindrica.
Bacteria added to algae in mid-log growth phase.
    N
                     c 2
                     br
Salmonella paratyphi
   8     222.0690  .1189
Salmonella typhosa
   8     11.0652   1.5269
Shigella paradysenteriae
   8     95.2742   .2458
Shigella dvsenteriae
   8     106.4579  .2418
Vibrio comma
   8     52.2653   .2336
                                    b
                                                                  R
                              (6.0783*.3755)   (-.0751^.0098)    .9737

                              (6.6067*1.3458)  (-.0601-.0351)    .6484

                              (6.8035*.5399)   (-.0707^.0141)    .9408

                              (6.7365*.5356)   (-.0742^.0139)    .9466

                              (5.1157*.5265)   (-. 0511*. 0137)    ,8970

-------
                                                                       90
                            Table A-59
Reduction statistics of pathogenic bacteria species with Anjc^stis nidul§ns_.
              Bacteria added to algae in mid-log growth phase.
    ,.T    o  2/q 2    Q 2             b                k           R
    N    SH /br     or	  	    -   	
                              <7.3962±.66S8)   (-.0840±.0174)   .9364

                              (6.3929±.6028)   (-.0758±.01S7)   -9359

                              (6.6402,1.2 HO)  <-.0981±.0317>   .8579

                              (6.8716i.5993)   (-.1249^0208)   .9671

                   .3186      (5.2S23±.7I16)   (-.0997±.0247)   .9299
                             Table A-60

 Reduction statistics of pathogenic bacteria  species with Gloeocapsa aMgola
               Bacteria added to algae in mid-log growth phase.

    N    SH2/Sr2    V2	   	b        	k         —	

                              (7.5863-1.5407)  (-.0657^.0401)    .6270

                              (5.6856^.5965)   (-.0609-.0156)    .9062
 Shiaella paradysenteriae                           rtn^0+ nno^
 ~~8	 341.4663   .0948      (6.5899^.3353)   (-.0832^.0087)
 Shigella dysenteriae                  ,            nr,AC+ nnm\
 	8     250.8821   .1036      (5.8648-.3505)   (-.0745-.0091)
 Vibrio comma                          .             »^r+ n»r,n\
 	8	191350    1.3396     (6.2735*1.2606)  (-.0755±.0329)

-------
                                                                        91
                             Table A-61

Reduction statistics of pathogenic bacteria species with Oscillatoria chalybia
               Bacteria added to algae in mid-log growth phase.
                     O 2              U                T,
    N
         sH2/sr2
Salmonella paratyphi
   8     14.8942   1.1813
Salmonella typhosa
   8     11.2542   1.1372
Shigella paradysenteriae
   8     15.7010   1.3518
Shigella dysenteriae
   8     61.3114   .3928
Vibrio comma
   8     228.8732  .0834
R
                              (6.6241-1.1837)  (-.0613-.0309)   .7128
                              (5.5874-1.1614)  (-.0523-.0303)   .6523

                              (6.3148-1.2663)  (-.0673-.0330)   .7235

                              (6.2078-.6826)   (-.0717-. 0178)   .9109

                              (5.1152^.3146)   (-.0639^.0082)   .9745
                             Table A-62

Reduction statistics of pathogenic bacteria species with Oscillatoria formosa.
               Bacteria added to algae in mid-log growth phase.

         S  2/Sr2     S 2	         b	k
    N
Salmonella paratyphi
   8     67.3622   .4893
Salmonella typhosa
   8     206.1572  .1061
Shigella paradysenteriae
   8     291.2393  .0623
Shiqella dysenteriae
   8     37.9589   .5839
Vibrio comma
   8     84.3495   .2766
                                                                 R
                              (6.2018^.7618)    (-.0839-.0199)   .9182

                              (5,2634-. 3547)    (-.0684±.0093)   .9717

                              (5.3232*.2718)    (-.0622*. 0071)   .9798

                              (5.0350^.8323)    (-.0688*. 0217)   .8635

                              (5.0534-.5728)    (-,0706-.0149)   .9336

-------
                                                                      92
                            Table A- 63
Reduction statistics of pathogenic bacteria species wit

faveolarum.  Bacteria added to algae in mid-log growth phase
    N
                                    b               k
                             (6.364li.4069)   (-.0790*.0106)   .9721


                             (4.8470±.7478)   (-.0602-+.0195)   .8571


                             (5.589^.6926)   (-.0791±.0181)   .9235


                             (5.1532±.7147)   (-.0670±.0186>   .8903



                   .3413      (4.6406±.6363)   (-.0658^.0166)   .9081
                            Table A-64



 Reduction statistics of enteric bacteria in algal growth medium under

 anaerobic conditions.


                      2                              k
                     Sr
                              (4.2661i1.0626)   (-.0131±.0253)   .179



                              (6.0776±.7381)   (-.0352±.0175)   .7657
 Escherichia coli                      +         .   _.Qn+ ^771     q?4l
 - 12 - 189.839   .0604      (6.8443i.3016)   (-.0490-. 0072)    .9743


                   1.1097     (4,7693±1.2928)  (-.0131±.0307)    .1287


                              (5.7946*1.0879)  f-.03i5t.0259)    .5459



                              (7.5824t.4524)   (-.0563*.0108,    .9571

-------
                                                                      93
                            Table A-65

Reduction statistics of pathogenic bacteria species in algal growth medium
under anaerobic conditions.
    N
Salmonella paratyphi
   12    2.0283    1.0080
Salmonella typhosa
   12    4.2477    .8056
Shigella dysenteriae
   12    46,3827   .2490
Shigella paradysenteriae
   12    1.2762    1.4087
Vibrio comma
   12    2.4089    .5228
                                                                 R
(5.2320*1.2322)   (-.0207-.0293)    .2886

(4.6221*1.1016)   (-.0268*.0262)    .4593

(6.5081*.6124)   (-.0492*.0146)    .9027

(4.2391*1,4567)   (-. 0194-. 0346)    .2033

(4.1682-.8874)   (-.0162-. 0211)    .3251
                             Table A-66

Reduction statistics of pathogenic bacteria in presence of culture of four
green algae species. Bacteria added to algae when in their mid-log growth
pha se.
    N
 Salmonella paratyphi
    12    35.0416    .3373
 Salmonella typhosa
    12    37.5767    .3051
 Shigella paradysenteriae
    12    46.6440    .3042
 Shigella dysenteriae
    12    48,0406    .1846
 Vibrio comma
    12    41.3008    .2528
                                                                  R
 (5.0683*1.0587)  (-. 1553-. 0617)   .9211

 (5.8014-.8522)   (-. 1156*. 0402)   .9038

 (5.7432*1.0055)  (-. 1702*.0586)   .9396

 (5.4882-.7831)   (-. 1345*.0457)   ,9412

 (5.0728*.9165)   (-. 1460*.0535)   .9323

-------
                                                                      94
                            Table A-67

Reduction statistics of pathogenic bacteria in presence of culture of six
blue-green algae species.  Bacteria added to algae when inttheir mid-log
growth phase.

   N     SH2/Sr2    Sr2              b              k           R
Salmonella paratyphi                              «
   1234.9980    .3504       (5.6754^.7463)   (-.0759*.0259)   .8750
Salmonella typhosa
   1240.8310    .3134       (4.9758*.7058)   (-.0775^.0244)   .8909
Shiqella paradysenteriae
   12   36.7898    .1841       (4.2882^.5409)   (-.0564^.0187)   .8804
Shiqella dysenteriae
   12   12.6987    .6502       (5.8225^1.4382)  (-.1124*.0673)   .7605
Vibrio comma
   IF   53.4203    .1396       (4.9777^.5765)   (-.0933^.0272)   .9303
                            Table A-68

Reduction statistics of pathogenic bacteria species in algal growth medium
                             Controls.

    N    SH2/Sr2     Sr2              b               ^           R
Salmonella paratyphi
   8     7.084    2.936       (4.7225*1.6467)  (-.0622*.0454)   .5414
Salmonella typhosa                                     ,
   8     75.1391  .3737       (S.3975-.6658)   (-.0775-.0174)   .92605
Shigella paradysenteriae
   8     26.9832  .9442       (5.0349*1.0583)  (-.0738*.0276)   .8181
Shigella dysenteriae
   8     30.5534  .8124       (5.0675*.9817)   (-.0728*.0256)   .8359
Vibrio comma                                          ,
   8     35.4679  .5158       (4.3030*.7822)   (-.0625*.0204)   .8553

-------
                                                                     95
                            Table A-69

Reduction statistics of pathogenic bacteria species with Ankistrodesmus
braunii.  Bacteria added to algae in mid-log growth phase.

    N    SH2/Sr2    Sr2             b                k           R
Salmonella paratyphi
   8    53.4130   .4618       (5 .2557^.7401)   (-.0726-. 0193)   .8990
Salmonella typhosa
   8    50.0659   .4051       (4.5382-.6932)   (-.0658*.0181)   .8930
Shigella paradysenteriae
   8    32.6928   .7621       (4 .9435*.9508)   (-.0730*.0250)   .8449
Shigella dysenteriae
   8    25.4007   .9202       (4.7347-1.0448)  (-.0707*.0272)   .8089
Vibrio comma
   8    62.7151   .2627       (4.1532*.5582)   (-.0593*.0146)   .9127
                             Table A-70

Reduction statistics of pathogenic bacteria species with Chlorella
pyrenoidosa.  Bacteria added to algae in mid-log growth phase.

    N     SH2/Sr2    Sr2               b             k            R
   6     16.7589   1.0565     (5.0966-1.3713)  (-.0950-.0495)   .8073
Salmonella paratyphi
   6     16.7589
Salmonella jyphosa
   6     29.6214   .6437       (5.4513-1.0704)  (-.0986±.0386)   .8810
Shigella paradysenteriae
   6     66.4033   .2931       (5.1800-. 7223)   (-.0996*.0261)   .9432
Shigella dysenteriae
   6     11.8522   1.1679      (4.4327*1.4418)  (-.0840-.0520)   .7477
Vibrio comma
         17.2831   .6330       (4.3459-1.0614)  (-.0747*.0383)   .8121

-------
                                                                        96
                            Table A-71

Reduction statistics of pathogenic bacteria species with Chlorella vulgaris.
Bacteria added to algae in mid-log growth phase.
         o  2 /o  2    a 2              u               V
    N
Salmonella paratyphi
   7     16.3117  1.2757
Salmonella typhosa
   7     13.2037  1.1533
Shiqella paradysenteriae
   7     15.7464  1.1842
Shiqella dysenteriae
   7     29.2807  .7786
Vibrio comma
   7     10.9643  .9153
                                   R
(4.6525*1.2950)  (-.0669*.0334)    .7654

(4.5957*1.2314)  (-.0572*.0317)    .7253

(4.1637*1.2477)  (-.0633*.0322)    .7590

(4.7370*1.0117)  (-.0700*.0261)    .8541

(3.5452*1.0970)  (-.0465*.0283)    .6868
                            Table A-72

Reduction statistics of pathogenic bacteria species with Scenedesmus
obliquus.  Bacteria added to algae in mid-log growth phase.
    •vr    o  2 /o i*     o £•
Salmonella paratyphi
   8    34.3155   .9453
Salmonella typhosa
   7    13.7076   .7617
Shigella paradysenteriae
   7    27.1390   .8834
Shigella dysenteriae
   7    18.2956   1.0167
Vibrio comma
      ,+
                                                                 R
(6.2250-1.0590)  (-.0833-.0276)    .8512

(4.5996*1.1003)  (-.0700-.0381)    .7327

(6.1021*1.1849)  (-.1061^.0411)    .8444
(5.3369*1.2712)  (-.0935-.0440)    .7854
         13.4125  1.2051      (4.9428*1.3843)  (-.0872*.0480)   .7285

-------
                APPENDIX B
BACTERIOLOGICAL DATA FROM LABORATORY AND
  FIELD WASTE STABILIZATION POND STUDIES
                     97

-------
                              Table B-l.  Total Bacteria Densities In Laboratory Scale Waste Stabilization Ponds, As Log10/ml.
Date
7- 3-69
7- 7-69
7- 9-69
7-11-69
7-14-69
7-16-69

7-18-69
7-23-69
7-25-69
7-29-69
Sample Station —
Raw #1
6.72673
6.46613
7.05757
7.34782
7.19576
7.49066

8.52022
7.92505
7.79449
7.12385
6.66346
5.97772*
6.99717
7.07372
6.10380
6.79239
\
6.79379
7.47276
6.26834
6.28948*
#2
5.97081
5.50106*
6.72148
6.41330
4.65369
5.01072

4.95425
6.50827
5.44871
5.01589*
#3
5.54407
5.08991
6.90227
5.78426
4.79727
5.09777

4.91803

5.19728
4.75587
#4
5.10380
6.12222
5.96190
5.98520
5.50718
5.44248

5.48572
6.20352
5.04922
5.13672
#5
3.32593
4.92942*
6.81023
6.60152
5.04115
4.59660

4.97405
5.34193
4.34133
4.33445*
#6
5.65992
6.11227*
6.58743
5.69174
5.47857
5.68679

6.04139
5.79344
5.94374
5.22272*
#7
4.88081
5.68574*
5.99388
6.23553
4.64836
4.97058

4.53782
5.07555
5.98989
5.48180*
#8
6.41119
4.00000*
5.48714
5.43377
5.32919
6.02794

5.62014
5.67486
5.42488
5.51455*
#9
5.53593
5.23045
5.64444
5.58546
5.49406
5.08955

6.38382
6.44739
5.31597
5.79623
#10
5.22011
6.65002
6.13928
5.62273
5.24613


5.21617
5.71012
5.77815
5.43933
#11
4.69940
6.07188*
6.28780
5.94052
5.20276
3.87506

4.58433
4.38075
4.09377
4.98453*
*lnoculation with laboratory cultures:  7-7 and 7-29 with E.  c. ,  Pseud. , and Serr.
                                                                                                                                                        CO

-------
Table B-2.  Total Bacteria  Densities In Laboratory Scale Waste Stabilization Ponds, As Log1()/ml.
Date
8- 4-69
8- 6-69
8- 8-69
B-ll-69
8-13-69
8-15-69
8-18-69
8-20-69
8-22-69
8-26-69
Sample Station —
Raw #1 #2
7.32531
7.66229
6.78013
6.74036
7.04630
6.96379
7.42243
7.12710
7.51851
6.87216
6.26411 5.12988
5.62685 4.32736
4.74819 6.95624
5.67669 4.19033
6.17099 5.29667
6.24304 5.36549
5.47712 4.75397
6.02531 3.98677
6.36680 5.20412
5.30103 4.16137
#3
4.69152
4.05115
6.81471
4.31175
4.63347
5.23553
4.45864
4.81624
5.94694
4.52504
#4 #5 #6
5.30211 6.19209 5.13751
3.97428 4.98080 5.56732
7.21885 7.60590 8.55781
4.61805 4.07278 5.67669
5.40184 4.15381 5.88804
5.02531 4.48714 6.29831
5.12711 4.48572 6.13513
4.49136 4.29994 6.30428
4.61278 6.69329
4.43537 4.11227 4.79588
#7 #8
5.63220 5.45255
5.33244 5.08279
8.46310 7.60487
5.04139 5.29003
5.09552 5.08458
5.16732 5.53782
4.92428 5.39226
4.07188 5.31175
5.49136 5.70372
4.70757 4.57113
#9
5.85643
4.96497
8.38462
5.37107
5.13988
5.73139
5.46613
5.41497
5.72937
4.68350
#10 #11
4.94349 4.96848
4.75397 4.51455
7.65715 7.34922
5.35218 4.75967
5.26717 5.09691
4.93197 5.70948
4.85126 5.13830
5.86332 5.09342
5.93952 5.54064
5.02119 4. 59934
to
CO

-------
                                       Table B-3.   Total Coliform Bacferia Densities In Laboratory Scale Waste

                                                          Stabilization Ponds, As Log^Vml.
Date
7- 3-69
7- 7-69
7- 9-69
7-11-69
7-14-69
7-16-69
7-18-69
7-23-69
7-25-69
7-29-69
Sample Station —
Raw #1 #2 #3 #4

5
4
5

6
5
6
5
6

.14613
.69907
.60746

.81258
.87216
.66039
.62839
.01807
4,
3
5
5
5
6
6
4
4
4
.88930 4.39794 2.08279
.92942* *
.07918 4.55630 5.59106 4.30103
.00000 5.36173 4.50515 5.06070
.07918 3.13830 3.62839 3.90309
.32222 4.13033
.43537 3.79588 2.81291 3.79588
.70329 0.97772 0.17609 0.17609
.73679
.28443* *
#5
0.74036 3.
* 4.
4.90714 3.
4.74036 4.
3.00000 3.

4.
4.31175 3.
3.
* 2,
#6 #7 #8 #9
71642 0.39794 3.87506 3.S4407
39902* * 2.00000* 3.97772
96614 4.67482
30103 4.60206 4.14613 4.38021
00000 3.77815 3.15381 3.12222

63599 3.75967 4.76343 4.76080
72632 4.25539 3.27875 2.87040
,87535 2.39750 2.95904
,95036* * 2.72815* 2.79571

2
2
4
2
3

4
4
2
2
#10
.00000
.30103
.00000
.14922
.56526

.17609
.49693
.51587
.63246
#11

1
3.26682

4.23045

1.57978
2.13033


inoculation with laboratory cultures:  7-7 and 7-29 with E. c., Pseud., and Serr.
                                                                                                                                                          o
                                                                                                                                                          o

-------
Table B-4. Total Coliform Bacteria Densities In Laboratory Scale Wastes
                  Stabilization Ponds, As Log10/ml.
Date
8- 4-69
8- 6-69
8- 8-69
8-11-65
8-13-69
8-15-69
8-18-69
8-20-69
8-22-69
8-26-69
Sample Station —
Raw #1 #2
5.19866
5.85126
5.75587
5.71600
5.78176
5.57978
5.08279
6.10551
5.86332
5,72222
3.40449 1.72222
1.07918
4.06633 0.30103
3.81291 1.49136
4.39794
4.65321 0.77815
4.37566
4.51521
3.84510 0.17609
3.84510
0
0
0
2

2
0
0
0
0
#3 #4
.54407
.84510 0.30103
.30103
.32222

.04139
.00000 0.00000
.00000
.00000
.00000
#5
3.00432
1.97543
1.02110
0.81291
1.25527
3.30103
0.90309
1.71391
1.71181
2.04238

2

2
3
1
4
3
2
2
2
#5
.02632

.95424
.17609
.99123
.65321
.29003
.95424
.52114
.49554
#7
2.20140
1.23045
1.06446
0.30103
1.51188
3.17609
1.72428

0.00000
0.17609
#8
2.05881

3.61278
3.06446
3.51851
3.69897
2.38021
3.14613
3.17609
2.77815
#9
1.80787
1.79934
0.95424
3.27875
3.50515
4.17609
3.34242
3.27875
3.14613
2.51055
#10
2.09078
0.69897
1 .92428
3.23045
3.14613
4.53148
3.2787S
3.11394
3.32736
2 .13672
#11
1.74624
0.90309

2.30103
1.76343
4.43136
2.40867
0.17609
0.30103
1.07918

-------
                                            Table B-5.  Escherichla coli Densities In Laboratory Scale Waste
                                                      Stabilization Ponds, As Log.-/ml.
 Date
Sample Station—
  Raw        #1
  #3
#5
  t8
tt9
#10
#11
7- 3-69

7- 7-69  4.74036
           4.54407

           3.74036*
7- 9-69  4.69954    5.07918   4.55630
7-11-69

7-14-69

7-16-69  5.49381

7-18-69  5.27875
           4.69897  5.36173

           4.95424  3.13033

           6.29447  3.00000

           5.06004
7-23-69   6.49206    4.86332   0.00000

7-25-69   5.06070    4.11394

7-29-69   5.41497    3.62325*        *
                             *    3.00496*          *

5.59660    4.30103    4.90687    3.96614    3.67685

4.38021    4.84510    5.74036    4.30103    4.39794

3.62839    3.90309    3.00000    3.00000    3.77815

           3.17609    4.30103    4.02119    3.47712

                                 4.11394

                      3.60206    3.21748



                             *    2.41664*
                               3.15381

                               3.17609

                    2.74036    3.84510

                    2.92942    2.03443
           3.12222

           3.60206

           4.04115

           0.00000

1.14613    2.81291
                                                                                     3.17609*   1.89487
         3.00000

         4.00000



         3.56526

         3.90309

         3.77815

         4.44560

         2.60206

         2.02531
         3.03080

         1.68124

         4.07918

         3.00000

         1.54407

         1.11394
*Inoculation with laboratory cultures: 7-7 and 7-29 with B.C., Pseud., and Serr.
                                                                                                                                              O
                                                                                                                                              oo

-------
Table B-6. Escherichia coli Densities In Laboratory Scale Waste
Stabilization Ponds, As Log.g/ml.
Date
8- 4-69
8- 6-69
8- 8-69
8-11-69
8-13-69
8-15-69
8-18-69
8-20-69
8-22-69
8-26-69
Sample Station —
Raw #1 f2 #3 f4 #5
4.95785 2.20276 1.72222 0.54407
4.37107 0.90309 0.60206
4.14613 3.27875 0.00000
3.65321
5.21748 3.81291
4.92942 4.00000
5.55023 3.54407 0.00000
5.27875 4.14613
5.26717 3.54407 0.00000
5.00432 3.39794
3.00453
1.97543
0.69897
0.30103

0.54407
0.84510
1.70969
1.71181
2.03941
#6
1.90309

2.07918
3.07918
1.30103
0.47712
2.69897
2.54407
1.73640
0.39794
#7 f8
2.12385 2.02531
0.87506
0.84510 3.00000
0.00000 3.84510
0.00000 2.60206

1.70969 2.92942
2.47712
2.30103
2.30103
#9
1.14613
1.30103

3.92942
2.54407
2.00000
2.84510
2.65321
2.79588
1.73838
#10
2.09078

1.11394
2.69897
2.30103
2.77815
2.95424
2.47712
2.81291
1.71181
#11
1.74624
0.90309

2.30103


0.69897
0.00000
0.00000

                                                                                                          o
                                                                                                          co

-------
                                         Table B-7.   Pseudomonas aeruginosa Densities In Laboratory Scale
                                                     Waste Stabilization Ponds, As Log  /ml.
 Date
         Sample Station—
           Raw       #1        #2
                       #3
             #5
                                                                              #8
                                              #9
  #10
  #11
7- 3-69

7- 7-69

7- 9-69

7-11-69

7-14-69

7-16-69

7-18-69

7-23-69

7-25-69

7-29-69
          4.30103

       *         *

          5.97772    5.97772

4.00000   5.30103
5.17609

3.87506
0.00000

       *   -       *          *

5.34242               3.00000

4.92942    3.00000    3.81291
                                                                 4.00000
                                            4.00000    3.77815
3.74036
4.00000
3.00000
                                                                                       2.00000
*Inoculation with laboratory cultures:  7-7 and 7-29 with E. c.. Pseud. , and Serr.

-------
Table B-8.  Pseudomonas aeruqlnosa Densities In Laboratory Scale
Waste Stabilization Ponds, As Log10/ml.
Sample Station —
Date Raw #1
8- 4-69
8- 6-69
8- 8-69
8-11-69
8-13-69
8-15-69
8-18-69
8-20-69
8-22-69
8-26-69 5.30103
#2 #3 #4 #5 #6 #7 #8 #9 #10 #11
4.17609 3.30103 3.69897 3.00000 3.47712
3.00000 3.00000



3.00000 3.00000 3.84510
3.00000 3.00000
3.00000
3.00000 3.77815 2.30103 4.74036
3.00000 3.74036 2.90309 2.79588 3.00000 3.00000 3.39794
                                                                                                        o
                                                                                                        en

-------
                                           Table B-9.   Serratia marcescens^ Densities In Laboratory Scale
                                                     Waste Stabilization Ponds. As Log  /ml.
 Date
Sample Station—
  Raw        #1
#2
#3
                                                                 #5
                                                                              #7
                                                                  #8
                        #9
#10
                                              #11
7- 3-69

7- 7-69

7- 9-69

7-11-69

7-14-69

7-16-69

7-18-69

7-23-69

7-25-69

7-29-69
                     5.64836    5.53782

                     4.75967    3.47712

                     2.81291    2.92942



                                2.00000
                    4.73038    4.74036
                               3.77815
3.90309
                                                                           3.77815
                                                                                       4.90309
                  *  4.12222*   4.24304    3.95424
                                      *   3.00000*   4.30103*
                                                                                      4.00000
                                                                                                 4.30103
                                                                                                             4.00000
*Inoculation with laboratory cultures: 7-7 and 7-29 with E. c.,  Pseud., and Serr.
                                                                                                                                                O
                                                                                                                                                CT)

-------
                                            Table B-10. Serratia marcescens Densities In Laboratory Scale
                                                      Waste Stabilization Ponds, As Log1()/ml.
           Sample Station—
  Date       Raw        #1        #2         #3         #4         #5         #6         #7         #8         #9         #10        #11


8- 4-69                        4.30103    4.16137                3.77815               4.19033               3.00000    3.39794

8- 6-69                        4.19033    3.30103

8- 8-69                                                                                                                4.74036

8-11-69

8-13-69

8-15-69                                                                    3.00000

8-18-69    5.00000

8-20-69

8-22-69

8-26-69
                                                                                                                                                O
                                                                                                                                                •si

-------
Table B-ll. Chromagen Densities In Laboratory Scale Waste Stabilization Ponds, As Log  /ml.
Sample Station —
Date Raw #1 #2 #3 #4 #5
7_ 3-69 5.36642 5.29003 4.74036 4.38021
7_ 7-69 4.00000
7- 9-69 5.07004 5.45484
7-11-69 5.84510 5.32222 5.54407 4.64836 5.37475 6.26245
7_14_69 3.87506 3.74036 4.06070
7_16-69 3.84510 3.77815 4.27875
7-18-69
7-23-69 6.06070 5.47712 4.52114 3.77815 5.35781 4.35784
7-25-69 6.63849 3.47712 3.00000
7 29 6g 3.47712 4.27875 2.69897
t6
4.70757

6.02531
5.01599
3,74036
4.77761

5.09342
4.41497
3.87506
#7
4.09691

5.74036
5.91566
4.00000
3.79588

4.07918
4.34242
4.46613
#8
5.62325

4.86332
4.74429
2.81291
3.19033

4.51851
4.60206
4.63347
#9
3.95424

5.07555
5.03743
3.66978
3.30125

6.00065
3.47712
4.77452
#10 #11
4.52504 4.13033
5.65992
5.74710
5.07918 5.63548
4.10551 4,30103


4.91116 2.55023
4.77815 0.81291
3.19033
                                                                                                                      o
                                                                                                                      00

-------
                             Table B-12. Chromagen Densities In Laboratory Scale Waste Stabilization Ponds, As Log1()/ml.
  Date
           Sample Station—

            Raw       #1
                                 #3
                                            #4
                                                      #5
                                                                 #6
                                                                   #8
                                                        #9
                                                        #10
                                                        #11
8- 4-69



8- 6-69



8- 8-69



8-llr69



8-13-69



8-15-69



8-18-69



8-20-69



8-22-69



8-26-69
6.47712



5.00000



5.69897
6.17609
                     4.94448   4.07004   3.86923
6.95424



3.47712



2.47712



4.81291



4.04139
           6.81291
                               4.03141



                               3.74036
                    4.61805    5.19033
5.11394



3.07004



7.21748



3.00000



5.10037



4.30103



4.04139
4.7493







7.60206



2.91645



3.94511



3.85278
4.61542



3.74036



8.55630



2.69897



5.67210



5.43933
5.17245



4.00000



8.46240



4.95424



5.06070



4.62325
5.37566







7.60206



4.30103



4.00000



5.09691



4.72428
5.85431



3.00000



8.38021



4.30103



3.47712



5.14998
3.55023







7.65321



4.47712








4.41498
4.73038



3.84510



7.34242



4.09691



5.01284



5.30103
                                                     3.75967    5.04139    4.54407    5.08991    5.24304    5.46240    4.93450
                                                                                                                                          o
                                                                                                                                          CD

-------
                                    Table B-13.  Total Bacteria Densities In Waste Stabilization Ponds, As Log  /ml.
Date
6- 4-69
6- 5-69
6- 6-69
6- 9-69
6-11-69
6-13-69
6-16-69
6-18-69
6-20-69
6-23-69
6-25-69
6-27-69
6-30-69
Sample Station —
#1 #2
6.34242
6.44716
6.73560
6.70842
6.70415
6.69984
6.59550
6.96100



6.69108
7.03262
6.35218
6.57978*
6.69897
6.02119
6.38202
6.58659
5.98677
5.72673
6.46240
6.82217

6.65706
6.35458
#3

6.30103
7.00000
6.67394
6.35025
6.28556
5.95904
5.90472
6.29885
6.48430

6.64246
6.34044

6
5
6
6
4
3
4
5
4


3
6
t4
.51455
.92428*
.14922
.20140
.81954
.00000
.74819*
.06819
.60206


.14613
.96656
#5

5.32222
5.43136
6.58883
5.55630
5.29667
5.67025
5.67302
4.47712


4.46850
4.38758
#6
4.98677
5.07918
5.69020
5.74036
4.56820
4.79934
4.74036
5.24304
4.27875
4.57978
3.95424
3.20412
3.25696

6
5
6
6
5
5
5
5

3

3
4
#7 f8
.15534
.66276 5.60206
.28780 5.69897
.65610 5.19866
.42975 5.39794
.45025 5.41497
.28330 6.34830
.17319 5.29885
*
.00000

.57978 3.50515
.57980 5.70672
#9
5.66276

S. 56820
4.84510
4.77815
4.94448
4.44716
3.60206
3.00000
4.85126
3.04139
3.20412
3.66783
#10 #11 #12




5.80482 5.79029
6.49136 6.25285
4.44716 5.29003 5.34242
5.17898 4.79239 3.30103
3.77815
* 3.60206
3.87506
5.46538 5.65992 3.89763
5.65300 5.78247 4.48195
*Inoculation with laboratory cultures: (6-5; E.  c..  Pseud.) (6-16; E.  c..  Pseud., Serr.) (6-19; shown as 6-20; E. C.,  Pseud., Serr.) (6-23; E. c..
Pseud., Serr.)

-------
                                     Table B-14. Total Bacteria Densities In Waste Stabilization Ponds, As Log10/ml.
Date
7- 2-69
7- 7-69
7- 9-69
7-11-69
7-16-69
7-18-69
7-21-69
7-23-69
7-25-69
7-29-69
7-31-69
Sample Station —
#1 #2
6.73878
7.29612
6.86629
7.34587
7.19576
7.49066
8.52088
7.92505
7.79449
7.12385
7.22272
6.98644
7.35362
6.36605
7.27646
7.37767
6.60016
7.96497
7.19033
6.82445
7.27646
6.92298
#3
6.93865
7.19590
7.03993
7.53656
7.10806
6.03523
8.25600
7.34635
7.19451
6.56820
7.14301
#4
5.37220
5.43616
3.87344
5.36577
5.59106
6.63829
5.77706
5.53013
7.28319
5.20548
5.77379
#5
5.48853
5.58092
5.42922
6.09412
5.78319
6.48053
6.19089
6.73632
7.17713
5.61262
5.52504
#6
4.10072
3.58192
5.47787
5.28780
4.16443
6.18064
4.86540
6.02735
6.26174
4.15987
4.45102
#7
5.14426
5.21484
5.17342
6.64147
5.51521
6.59555
6.33163
6.50853
6.28171
5.29115*
5.33746
#8
5.23259
4.98227
5.40747
6.22154
5.38471
6.35005
6.18227
6.57119
6.50127
5.36949
5.26600
#9
5.18611
4.74819
4.87484
5.88053
4.52827
5.33011
5.25139
5.79955
5.44754
4.24055
2.94201
#10
5.72835
5.22660
6.27140
6.21163
6.44091
6.82086
6.38739*
7.12548
6.72016
6.08814
6.02325
#11
5.76530
5.61013
6.63624
6.37658
6.38292
6.62428
7.22789
6.93717
7.13815
6.14768
5.56229
#12
S. 30604
5.07004
5.74321
5.85187
5.96308
6.62926
6.43553
6.86608
5.39094
5.24920
4.92169
*Inoculation with laboratory cultures:  7-21  and 7-29 with E. c., Pseud., and Serr.

-------
Table B-15. Total Bacteria Densities In Waste Stabilization Ponds, As Log  ./ml.
Date
8- 4-69
8- 6-69
8- 8-69
8-13-69
8-15-69
8-18-69
8-20-69
8-22-69
8-26-69
Sample Station —
#1 #2
7.33244
7.66229
7.05207
7.04630
6.96379
7.42243
7.12710
7.51851
6.87216
7.24981
6.93069
7.20880
7.08636
7.22789
6.91116
7.22531
7.29115
6.84819
#3
6.98000
6.99344
7.29170
7.08189
7.48996
7.29447
7.26186
7.29336
6.84973

4
6
6
6
7
6
6
7
6
#4
.67210
.12215
.40140
.88550
.28499
.80702
.46165
.05018
.67440
#5
6.33496
5.99100
6.63849
6.82102
7.14613
6.87938
6.71391
6.87520
6.54777

5.
5.
5.
4.

6.
6.
6.
5.
#6
63246
55991
49136
96379

13909
37475
89708
72428
#7
5.62480
5.58574
7.20412
7.05300
7.38828
7.15503
6.81067
7.42854
6.16584

5
5
6
6
6
6
5
7
5
#8
.56526
.79934
.44770
.61316
.84510
.73739
.79831
.25768
.72222
#9
5.04336
5.37794
5.93197
5.78645
5.93827
6.24748
5.64738
6.47276
5.59988
#10
6.62660
5.55961
6.46117
6.34586
6.71904
6.55023
5.93827
6.89070
5.54407
#11
5.63849
5.92634
6.35338
6.25467
6.66745
6.87795
6.02531
6.30049
5.55328
#12
4.97313
4.98453
5.66229
5.15076
6.12548
5.83727
5.60959
6.56926
5.31755

-------
                                Table B-16. Total Coliform Bacteria Densities In Waste Stabilization Ponds,  As Log n/rnl.
Date
6- 4-69
6- 5-69
6- 6-69
6- 9-69
6-11-69
6-13-69
6-16-69
6-18-69
6-20-69
6-23-69
6-25-69
6-27-69
6-30-69
Sample Station —
#1 #2

5.47712
5.77815
5.77670
5.98137
5.77815
5.90309
5.02938
6.23045
5.75587
5.80618
6.51983
5.85733
5.69897
5.30103*
5.60206
5.70969
5.00000
6.21484
4.77085
5.17319
5.04139
4.92942
4.65321
4.77815
4.60206
#3

5.00000
5.47712
5.83569
4.81954
4.93450
4.66276
5.17609
5.04139
5.43136
4.96848
4.84510
4.77815

5
4
4
5


2
0
2
4
2
0
0
#4
.60206
.20412*
.17609
.15836


.69897*
.69897
.20140
.90309
.40483
.69897
.00000


4
4
3
3
3
4
1
1

0
1
0
#5

.11394
.39794
.69897
.00000
.17609
.39794
.86923
.64345

.69897
.25527
.54407
#6

3.90811
2.80625
1.74115

2.93450
1.63347
1.59106
1.72428
1.86332

1.87216
1.92942

5
4
5
4
3

3
2
3
1
2
3
1
#7
.47712
.54407
.81889
.88081
.92942

.84510
.71349
.00000*
.13033
.88053
.04532
.44716
#8

4.34242
3.90309
3.47712
4.14613
4.25527
3.69897
3.19285
3.84510
0.60206
1.32222
3.18752
0.45788
#9 #10 #11 #12

3.77815


4.74819 4.57403
4.83885 4.43136
3.74036 3.87506 2.69897
0.00000 3.37840 2.00043 1.04139
3.84510 3.60206 0.97772
4.17609 * 3.00000
1.39794 3.03342 2.53020 0.77815
2.94349 3.48430 0.77815
0.54407 2.95665 0.30103
*Inoculation with laboratory cultures:  (6-5; E.G., Pseud.) (6-16; E.G.,  Pseud., Serr.) (6-19; shown as 6-20; E.  c.,  Pseud., Serr.) (6-23; E.G.,
Pseud., Serr.)

-------
                                Table B-17.  Total Coliform Bacteria Densities In Waste Stabilization Ponds, As Log   /ml.
Date
7- 2-69
7- 7-69
7- 9-69
7-11-69
7-16-69
7-18-69
7-21-69
7-23-69
7-25-69
7-29-69
7-31-69
Sample Station —
#1 #2
5.62325
6.12304
5.59934
5.65321
6.81258
5.87216
6.17464
6.66039
5.62839
6.01807
4.89209
4.90300
5.19728
5.77815
5.27875
5.24304
5.14922
4.96848
5.27068
4.59660
4.29003
5.05500
#3
5.07004
4.74036
5.17609
4.64098
4.89900
4.89209
4.65801
5.51117
4.94448
4.73838
4.06633
#4
2.70136
0.69897
0.60206

2.94201
2.84261

2.02735
0.00000
0.00000
2.00304
#5
0.02119
2.70265
2.70243
1.21748
3.20412
3.92686
0.00000
2.13354
2.84510
2.00000

#6
2
0.30103 3
0.54407 1
0.74036
4
3
3
0.90309 4
3
0.47712 2
0.14613 3
#7
.75797
.49534
.31175

.02119
.46240
.83727
.01912
.66745
.74036*
.31175

2
3
3

3
3
3
4
3
2
2
#8
.71204
.19770
.84510

.94939
.55630
.47349
.66978
.74036
.97772
.90309
#9
0.47712
0.60206
1.81291

1.00000
1.13033
1.29003
0.30103
0.30103

0.90309

3
3
3
2

4

4
3
1
5
#10
.42704
.49631
.69897
.03141

.48359
*
.09342
.37107
.90445
.13354
#11
2.77670
2.80058
0.84510
2.81291

3.86332
3.90982
3.11394
3.89487
3.50174
3.19033
#12
2.70286
0.47712
1.17609


3.90300
0.54407
0.77815
1.24304
0.47712
1.49831
*Inoculation with laboratory cultures:  7-21 and 7-29 with E. c. ,  Pseud., and Serr.

-------
Table B-18. Total Coliform Densities In Waste Stabilization Ponds, As Log., ./ml.
Date
8- 4-69
8- 6-69
8- 8-69
8-13-69
8-15-69
8-18-69
8-20-69
8-22-69
8-26-69
Sample Station —
tl #2
5.19866
5.85126
5.75587
5.78176
5.57978
6.08279
6.10551
5.86332
5.72222
4.99782
4.71809
4.54407
4.96142
4.81790
4.97081
4.92686
4.90037
5.07225
#3
4.86332
4.53148
4.92942
4.69461
4.88081
3.72428
4.96142
4.65801
4.84819
#4
0.30103
1.78176
1.17609
1.97658
3.92169
3.03141
2.15381
2.00432
3.13409
#5
2.00000
2.87852
2.88944
2.55509
3.47712
3.09691
3.71809
1.91116
3.50379
#6
1.30103
0.00000
1.00000
0.47712
1.55630
0.60206
2.47712
0.00000

#7
2.47712
3.51188
3.99123
4.11561
3.82607
3.96379
3.84354
3.84819
3.29003
#8
2.30103
3.27875
3.52504
3.46982
3.67210
3.72222
3.89625
3.34242
3.68124
#9
0.77815

1.00000
0.90309
1.72016
0.65321
1.72016
2.41664

#10
3.13033
2.81291
2.00647
3.65321
3.95424
3.16137
3.63849
3.61013
3.24304

3
3
4
3
4

3
3
3
#11
.00000
.75967
.59106
.60314
.14301

.47712
.55630
.74233
#12
0.77815

0.30103
1.17609
2.15076
1.71181
2.01072
1.78355
2.50651
                                                                                                                Cn

-------
                                   Table  B-19.  Escherichla coll Densities In Waste Stabilization Ponds, As Log.  /ml.
	 iu
Date
6- 4-69
6- 5-69
6- 6-69
6- 9-69
6-11-69
6-13-69
6-16-69
6-18-69
6-20-69
6-23-69
6-25-69
6-27-69
6-30-69
Sample Station —
#1 #2

5
5
5
4
5
5
4
5

5
5
5

.00000
.00000
.23553
.81954
.00000
.39794
.19033
.97772

.34242
.67210
.58546
5

5
3
4
4
3
5
4
4
4
4
4
.30103
*
.00000
.92942
.11394
.88195
.69897
.03743
.84510
.54407
.00000
.74036
.47712


5
4
4
4
3
3
4
4
4
4
4
#3 #4 #5 #6 #7

3.84510* 3.30103
.00000
.06070 3.97772 3.30103
.46240
.34242 2.69897
.39794 *
.17609 0.30103
.72428 1.89763 2.43457
.60206 0.69897
.39794 0.60206 0.17609
.77815 0.00000 0.47712
.65321 0.00000 0.30103

4.04139 3
4.75587 3
4.42813 2
3.00000 3
3
3.17609 3

* 3
0.00000 0
2.40140 0
2.77085 3
1.30103 1
#8

.00000
.75587
.69897
.39794
.81291
.17609

.60206
.39794
.00000
.02531
.54407
#9 #10 #11 #12

3.00000


3.54407 3.47712
3.39794 3.00000
3.00000
0.77815 1.46240 0.87506 0.54407
0.17609 1.69897* 3.47712 0.47712
3.39794
0.17609 2.94448 1.54407 0.17609
3.35218 2.77815 0.00000
0.17609 1.99123
*Inoculation with laboratory cultures: (6-5; E. c.. Pseud.) (6-16; E.  c.,  Pseud., Serr.) (6-19; shown as  6-20; E. c. , Pseud., Serr.) (6-23; E. c. ,
Pseud., Serr.)

-------
                                   Table B-20. Escherichia coll Densities In Waste Stabilization Ponds, As Log  /ml.
Date
7- 2-69
7- 7-69
7- 9-69
7-11-69
7-16169
7-18-69
7-21-69
7-23-69
7-25-69
7-29-69
7-31-69
Sample Station —
#1 #2
5.04139
5.46613
5.44248

5.49381
5.27875
5.54407
6.49206
5.06070
5.41497
4.67210
4.17609
5.06070

4.68970
4.69897
4.45102
4.75587
4.97772
3.92942
4.13830
4.78533
4
4
S
3
4
4
4
4
4
4
3
#3 #4 #5
.82930 0.30103 0.00000
.30103 0.39794 0.47712
.00000
.30103
.57403 2.00967 2.00000
.41497 2.57692 2.00000
.10551 0.00000
.58546 2.01599 1.90309
.39794 2.00000
.48430
.66976
#6
1.
0.30103 3.
0.54407

3.
2.
3.
0.00000 3.
3.
3.
3.
#7
46240
24920


63347
90309
49136
78176
14613
47712*
11394
#8
0.77815
3.24834
3.30103

3.41078
3.04139
3.50515

2.90309
2.54407
2.77815
#9
2
0.00000 3
2
2
0.30103 3
0.69897 3
0.00000
0.00000 3
0.00000 2
2
4
#10
.89154
.00000
.00647
.80647
.59660
.43933
*
.65801
.81291
.30103
.66276
#11
2.70906
1.60746


3.67669
3.24304
3.03141
3.69897
3.14613
2.84510
2.97772
#12
0.60206
0.00000


0.81291

0.30103

0.30103


*Inoculation with laboratory cultures:  7-21 and 7-29 with E. c. , Pseud., and Serr.

-------
Table B-21. Escherlchia coll Densities In Waste Stabilization Ponds, As Log   /ml.
Date
8- 4-69
8- 6-69
8- 8-69
8-13-69.
8-15-69
8-18-69
8-20-69
8-22-69
8-26-69
Sample Station —
#1 #2
4.95785
5.37107
5.14613
5.21748
4.92942
5.55023
5.27875
5.26717
5.00432
4.66745
4.27875
3.90309
4.51188
4.32736
4.62066
4.14613
4.37107
4.30643
#3
4.11394
4.14613
4.25527
4.06691
4.16137
3.43933
4.20412
4.14613
4.00432
#4


0.84510
1.75967
3.86332
2.84510
1.73640
0.17609
2.14535
#5

0.47712
1.72428
2.18184
2.84510
2.82930
2.00000
1.72428
2.49693
#6

0.00000 3
0.30103 3
2
0.60206 3
3
3
3
3
#7

.20412
.23045
.92942
.20412
.56229
.30103
.26717
.07918
#8

3.00000
3.84510
2.90309
3.17609
3.33244
2.81291
2.94201
3.04139
#9
0.30103

0.30103
0.00000
1.25527
0.30103
0.30103
1.70329
2.35218
#10
2.65321
2.69897
2.54407
2.77815
2.90309
2.95424
3.06070
2.90309
2.91645
#11 #12
2.84510
3.. 2 78 75

2.65321 0.30103
2.92942 0.65321
2.00000
3.00000 0.00000
2.88930 1.71809
3.13830 0.77815
                                                                                                                    oo

-------
                              Table B-22. Pseudomonas aeruginosa Densities In Waste Stabilization Ponds, As Log1Q/ml.
 Date
Sample Station—
  #1         #2        #3
#4
#6
#8
#9
#10
#11
#12
6- 4-69

6- 5-69

6- 6-69   5.00000

6-11-69

6-13-69

6-16-69

6-18-69

6-20-69

6-23-69   4.81291

6-25-69

6-27-69

6-30-69   5.00000
           3.00000
                     3.00000
           3.17609
           5.00000  4.00000
                                       *    3.00000
                               0.00000
         3.30103
                                                                3.00000
                    0.00000
                               0.60206    0.30103    0.00000
                                          3.77815
                                                                                                 3.00000
                    2.69906    3.00000    3.00000*    5.87506

                    4.60206
*Inoculation with laboratory cultures:  (6-5; E.  c., Pseud.) (6-16; E. c.,  Pseud.,  Serr.) (6-19; shown as 6-20; E. c.. Pseud., Serr.) (6-23; E. c.,
Pseud., Serr.)
                                                                                                                                            CO

-------
                               Table B-23. Pseudomonas aeruainosa E)ensities In Waste Stabilization Ponds, A* Log
Sample Station —
Date #1 #2 #3 #4 #5 #6 #7 #8 #9
7- 2-69 5.30103
7- 7-69
7- 9-69 0.69897 0.97772 0.00000
7-11-69 3.00000
7-16-69
7-18-69
7-21-69
7-23-69
7-25-69
7-27-69
7-29-69
#10 #11 #12
3.00000
1.04139
Mnoculation with laboratory cultures:  7-21 and 7-29 with E. c., Pseud., and Serr.

-------
Table B-24. Pseudomonas aeruginosa Densities In Waste Stabilization Ponds, As Log  n/ml.
                                                                              10'
Sample Station —
Date #1 #2 #3 #4 #5 #6
8- 4-69
8- 6-69 6.30103 3.47712 3.00000
8- 8-69 5.00000
8-13-69 6.00000
8-15-69 5.00000
8-18-69
8-20-69
8-22-69
8-26-69 5.30103 4.00000
#7 #8 #9 #10 #11 #12
3.74036
3.09691 4.30103 3.17609
4.00000
3.30103 3.74036 3.00000
                                                                                                                    tsj

-------
                                Table B-25.  Serratia marcescens Densities In Waste Stabilization Ponds, As Log1Q/ml.
         Sample Station—
 Date       #1         #2
#3
#4
#5
#6
#7
#8
#9
                                                                   #10
                                                                                         #11
                                                                                         #12
6- 4-69

6- 5-69

6- 6-69

6- 9-69

6-11-69

6-13-69

6-16-69

6-18-69

6-20-69

6-23-69

6-25-69

6-27-69   5.00000

6-30-69
                    5.00000
                                                                                       3.00000
                                                                            3.60206    6.76716

                                                     4.30103

                    3.69897               0.30103                           0.30103

                               2.69914           *               3.00000
*Inoculation with laboratory cultures: 7-21 and 7-29 with E. c. , Pseud. , and Serr.

-------
Table B-26. Serratia marcescens Densities In Waste Stabilization Ponds,  As Log   /ml.
Sample Station —
Date #1 #2 #3
8- 4-69
8- 6-69
8-< 8-69
8-13-69
8-15-69
8-18-69
8-20-69
8-22-69
8-26-69
#4 #5 #6 #7 #8 #9 #10 #11 #12

3.00000 3.77815 3.00000 4-.17609 3.74036
3.00000 4.04139 4.00000

4.00000 4.77815
4.00000 4.00000
5.17609 4.00000


                                                                                                                 CO

-------
                                     Table B-27.  Chromagen Densities In Waste Stabilization Ponds, As Log1Q/ml.
Date
6-30-69
7- 2-69
7- 9-69
7-11-69
7-18-69
7-21-69
7-23-69
7-25-69
7-29-69
7-31-69
Sample Station —
#1 #2
S
5
5
5

5
6
6

5
.17609
.54407
.07004
.84510

.69897
.06070
.63849

.00000
5
5
6
6
6
5
5
6


. 15381*
.39794
.11644
.96848
.50515
.60206
.69897
.32222


5
5
6
7
5
6
5
6
0

#3
,60206
.39794
.19451
.28103
.77815
.00000
.90309
.63347
.00000


3
4
2
5
6
3
6
6
3

#4 #5 #6
.35392 3.00475 3.00303
.38021
.70372 4.77452 5.01912
.17026 5.53593 4.87338
.23465 5.65562
,00000
.19866 6.74135 5.69858
.41747 6.86004 5.93044
,74086 2.54407
3.00000 2.47712
#7
3.00260 3
5.04532 4
4.33415 4
6.27875 4
6.17826 5
5
6.08027 5
5.91619 6
* 2

#8
.60206
.93952
.51382
.38021
.92763
.39794
.96755
,04001
.17609

#9 #10 #11 #12
1.73239 3.44404 3.47712 3.01452
3.47712 3.97772
4.37493 5.92428 6.27300 4.20656
5.92763 5.35698 5.69020 5.26007
4.99454 6.30750 5.72835 5.63949
4.40824 * 6.05500
5.40697 6.71809 6.59638 6.50583
4.83569 6.34044 6.71684
4.65321

*Inoculation with laboratory cultures:  7-21 and 7-29 with E.G., Pseud., and Serr.
                                                                                                                                                    to

-------
Table B-28. Chromagen Densities In Waste Stabilization Ponds, As Log10/ml.
Sample Station —
Date #1 #2 #3
8- 4-69 6.47712 6.53148 6.00000
8- 6-69 6.00000 6.27875 6.13830
8- 8-69 5.69897 5.30103
8-13-69 6.35218 6.47712
8_15_69 6.35218 6.477:2
8-18-69
8_20_69 6.69897 6.37107
8-22-69 6.17609 6.09691 6.27875
8-26-69
#4
4.91381
5.89625
5.96731
6.84042
6.84042
6.07004
5.69897
6.45102

6,
5
6
6
6
6
6
6
#5
.26717
.82930
.19728
.76343
.76343
.60206
.57978
.22337
#6 #7
5.60206 4.21748
5.46761 4.67897
5.17934
7.02016
7.02016
5.57403 7.11394
5.57978 6.70969
6.69461 7.07555

5,
5
5
6
6
6
5
6
#8
,24428
.33746
.39138
.54407
.54407
.69897
.34242
.86629
#9
4.95454
5.29885

5.69897
5.69897
6.19728
4.23045
6.13033

6,
5
5
6
6
6
5
6
#10
.61013
.29003
.37143
.18255
.18255
.51188
.69020
.51851
#11
5.49136
5.25888
5.29281
6.10551
6.10551
6.84510
S. 70757
5.84819
#12
4.62839
4.66511
4.81624

5.54095
5.60206
5.31702
6.24981
                                                                                                           ts?
                                                                                                           en

-------
     APPENDIX C




PROGRAM BETA FORMAT
          126

-------
                                                                                   127
000002
000002
000002
000002
00000?
000002
000002
000002
000002
000002
000002
000002
000002
000002
000002
000002
000002

000002
000002
000002
000002

000002
000002
000002
000002
000002
000002
000002

000002
000002
000002
OOOOC2
000002
000002
000002
000002

000002
000002
000002
                       BFTA(INPUT,OUTPUT)
               DIMFNSION IKOEXO*) »Y<*00> »X (20,400) ,«UOO) ,TABUF.13*»3) »A\20»20> .
              JYX(20).8 ,CfoT(20,20)»RDrT(20),CINV(20»20)«NSU8(20)»0p(20)»
              2CCVA«'20,?0)«SU1(2n),PSTAR(?0)«FORM2(5>.
              3FCRM(7> ,CM20,2A) ,C (20,20 )»v/ARI (400) ,YHnT (400)
               DIMENSION YHATT(*nn>»  YUP(4nO),  YLO»(40n),  DELTY(400)
               DIMENSION ,ICFLL

               CCMMON/6/TABLF
               CCMMON/C/\
                  KTA6LFB1.,2.»3.»4..5..6..7..fl..9.»lo..n..l2..13.»»*.,l5,»l6.
              5ft.3138, 2.<9?00,2. 353*,?. 1318,?.0150 0.9*32, 1.89*6, 1.6595, 1.8331,
              61.«125,1.7959, l.r«?-3, 1.7709. 1.7613 ,1,7530, 1.7459. 1.7396, 1.7341,
              71.7291,1.7?47,1.7207,1.7171,1.7139.1.7lo^.l.7081,1.70S60.7033,
              81.70U,1.A991.1.6973,J.6839,1.6707.1.6577,1.64*9.
              1         I?. 706,«.3027,3.1625,2.7764,2.5706,2.4469,2.3646.2.3060,
              22.2622,2.2281,2.2010,2.1788,2.1604,2.1448,2.1315,2.1199.?.1098,2.1
               4,2.0*8*.2.0*52,2.0*23,?.0211,2.0003, 1.9799,1.9600)
              1  FORMAT  (I?,A3,5X,A7)

             38  FCRMAT(29U<.?H?X(I2,17H) AFTFP REMOVING  12, 1*H (2HX (12,2H)  )))
             65  FORMAT(5F?0.In)
             66 FCRMAt(SH A-M.ftTRlX /)
             f,7  FCRMAT(//50H INVERTED A-MATBTX  (C-MATRIX)  /)
             f 0  r v. T^ >" •'•* ' \ r f I i r  i.. " M '" •"• ' '  ' ""-' "
             75  FORMAT (X/Tfth RFGWESStrN  COEFFICIENTS              /)          -...,,.
            ,«=60FCRMAT  (//«CH TnTAL CALCULATED  FROM DATA  OI6FERS FROM TOTAL CALCUL
                     BY SUMMING COMPONENTS BY                FeQ.10/YI
».05
mt)6
FORMAT (3H P(I?,"=H)
         ?r>). pUF TO
                                     =  F20.1f)
                                                 I502X.-5E20.10//15H
                                                          19, 12X.E20.10)
                                                                               FROM
            f,\*
            A15
           H61
            <>17
    FORMAT (1?..?*4)

    FcKl'HTIn?,«,m   - F2a.in,ioH   */.    F2ouo>
    FCRMATU5I-  VAPItNCE  OK YII3.3H) *F2n.lO)
    FCRfAT13HOV(I3,RH)   sF20.1n,10H   +/-
    FORMAT  (    -»HRY(13,?H)  = F?0 . 1 0 ,5X ,F?Q . I 0 .5XF20 . 1 0.5XF20 . 1 0
    FCRM6l(/4nM'"ML'LTlPl.F. CORRELATION COFFFIrlFNT  (H) « E20.1"//
      17H  VAHI«\CF  RATIO * E20.1"//)
                                                           F20.10,5X,F20.lO,Fl0
                                                                4)
                                                                I
                FCRMAT(SF?n,10)
                FCPMAT!//?4K  CONFIDENCE LIMTTS CF 8 )
                                        ' ON    •'
^eg FCRMATC3H ...	,._
fcqj FORMAT (12e,i2X,-»E2n. In)
^5 FCRMATOH x',I?.)OH) REMOVED 11 0 , l2X,3E2n . 10J
ft40 FORMAT{//Ofth   SOURCE        DEGREES OF  FRE5DOM
    IRE5          VARIANCE      VARIANCE RATTO   //)
*,61 FORMAT (1H(T2,15M(3H X(I2,2H) )))
700 FCRMAT(7H PSS = F20.1")
701 FCRMAT(13H F-KEto MATRIX//4(*F?0.1O/))
                                                                         OF
                                                                                SC.UA
000
001
002
003
004
005
006
007
008
009
010
t)U
012
013
014
015
016
017
018

020
021
022
023
024
025
026
027
02fl
029
030
031
032
033
 03*
 035
 036
 037
 038
 039

 040
 041
 042
 043
 044
 045
 0*6
 047
 048
 0*9
 050
 051
 052
 053

-------
                                                                           128
 000002
 000002
 000002
 000002
 000002
 000002

 000002

 000002
 000002
 000002
 000002
 000002
 000002
 000002
 000010
 000022
 000030
 000040
 000043
 000052
 000056
 0000«4
 000071
 000076
 000100
 000102
 000111
 000111
 000115
 OOOIZ4
 0001J5
 0001)21
 000132
 000134
 000135
 000136
 OOOIEO
 000154
 0001*4
 0001^7
 000171
 000172
 000202
 000206
 000212
 000214
 000215
 000225
 000330
 000334
 000341
 000246
 000352
 000354
000273
000300
  702 FORMAT <26w LEAVING CUT VARInPLE NC.  I2//13H NEW C-MATRIX//)             054
  705 FCRMATI///)                                                               055
  720 FCRMATllHl )                                                               056
  721 FCRMAT(67x,27H     DEVIATION           0/0    )                            057
  7?2 FORMAT <35(- THE AVERAGE ABSOLUTE DEVIATION  IS  Fln.4,9H PERCENT.)        Q58
 7?21 FORMAT (3nH  ABSOLUTE AVERAGE DEVIATION  =  ,F20. 10 .20HCONFTDENCE  FAC
     1TCR  =  .F?n.lO)
  7?3 FORMAT < 10< , 1 OH INPUT 0«TAt//tSX» IHYi 15X t ?*M VALUE (S) -LEFT TO RIGHT      059
     1)                                                                         060
  72* FORMAT
 7?41  FORMAT
  726 FORMAT!//)                                                               061
 13?7 FCRMAT(//Pl|-  ANALYSIS OF VAojANCE )                                      062
 16?8 FCRMAT(//?4H  COfFJDENrE LIMTTS OF Y  )                                    063
 4040 FORMAT (19M26H wlTH LIMITS rFtlS.llH PERCENT//))                        064
   99 READ 600.TMCFX                                                           065
      RtAO l.NGl FSS.Mf/Q.TYPp
      READ 724,  ( ICELL ( I ) • 1 = 1 18)
      READ 60). ".K                                                              066
      KKON = PO  *  5 • NGUESS                                                   OAS
      ENCODE (33. 4<>4ntFORM2)KKON                                                069
      PRINT  720
      PRINT  7241 .(ICELL(T) »T"1«8)
      PRINT  723*NCTff = n
      IF (MMG.fcO.ii-NCNlS.SSg                                                    071
   5  MG=]   $vMC=lfNOTE=]                                                       072
      DC 100 „=! ,M                                                              073
  100  C*LL IOATA (Y(J) ,X(ltJ> .NOTE)                                              074
      00 TO  863                                                                 075
  t; 111.4930                                              098
4038  TF ( INDEX (1 3) .F0.3HYFS)  1000. 1001                                          099
iftOO  Pf-TNT  66                                                                  100
      DC 61  1=1. M                                                               101
  61  PKJMT  65. M (I,J) »J=1,M                                                   102
infll  IF ( INDEX ni) .F0.3HYES)  1002.1003                                          103
1002  PRINT  67                                                                  104

-------
                                                                          129
0003C*
0003C6
0003?5
000332
00033*
000335
000336
000350
0003?*
00036*
000367
000371
000*10
000*15
000*21
000*30
000*3*
000*41
000443
000444
0004=7
000461
000*62
00047?
000500
000501
000512
000513
000515
000515
000516
000517
000527
000532
00053*
000540
000545
000547
000550
000552
000554
000555
000560
000562
000563
000570
000574
000600
000626
000630
000631
000635
000643
000647
000654
000655
000657
000660
     DC fcO 1 = ] ,N
  *0 PRINT 65, If(I,J) ,J = 1»N )
1003 IF ( INDF.X (1 0) .F0.3HYFS)42,43
  42 DC 44 1=1,N
     DC 44 J=l,N
     9lM=0»
     DC 45 K=] ,N
  45 9lM=SUM»C(T,K)««(K,J)
  44 CCnT(I,vJ)=SLM
     PRINT 70
     DC 71 I=1,M
  71 PRINT 65,(TOOT(I•J)»J=l«N)
  43 IF(INDFX(14).E0.3HYES)  1004,1005
100* PRINT 68
     PMNT 65, (YX (I) , 1 = ] ,N)
1005 PRINT 75
 111 IF ( INOF.X (i ) .EC.3HYFS) 7,150
   7 DC « I = 1 . K
   a
 150 DC
           605.K|R(T>
        152 W' = 1.M
 1*3
 15*
     DC 152 1 = 1,N
     Yt-AT(J)»YMM(j)*X(t»J)»P(I)
     SlMl=0.0
     DC 153 jsl.V
     9LM1=SUM*Y(J)
        R = SUfl/F[ OAT  (M)
     SSP=0.0
     DIUFR=0.0
     DIFFsO.O
     DC 15* J=l,C
     SSR=SSR+(YHAT(J)-YBAR)«»2*W(J)
     DIVFR=OIVFP«(Y(J)-YHAT(J))»«2«W(J)
     DIFF =OIFF «rY(J)-YHAC)«»2»W(J)
     IF (MMQ.fcQ.^HNON;) 1006,1007
1006 NCR=N-1
     RC TO lOOfl
1007 NCR=N
100B NCFR=f-N
     NTOT = K -1
     SCDf = SSW/FI.CAT
     S2=DIVFfi/FI OAT
     FsSMflR/S?
     IF(INDEX (?).F0.3HYFS)1S1»ZOO
     PRINT 1327
     PRINT 660
     PR TNT 60A,NDR,SSR,S^DR,F,NOFP,OIVFR,S2»KTCTfOIFF
     TCTAL a SSP+DTVFR
     DEV=OIFF-TOTAL

     PRINT 156. OEV
     PRINT 660
     DC 175 1*1 ,A
     NCFR=1
 151
 155
105
106
107
10«
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
1?7
12S
129
130
131
132
133
13*
135
136
137
138
139
  A
  B
  C
  0
141
142
1*3
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159

-------
                                                                          130
0006*1
0006*3
00070*
000711
000715
OOOT27
0007.36
0007*2
000752
0007=3
000756
000757
0007(1
000773
00077*
00100*
001010
001012
001013
001015
001032
00103*
001037
001041
001042
0010=2
001065
0010(2
001063
001070
001072
00107*
001075
001076
001101
001110
001171
0011*0
00114*
001146
001147
OOH57
0011*2
oom?
001170
001175
001177
001201
001203
001213
001232
001336
001837
00124*
001246
001356
0013(3
0012(6

175
167
IPO





157




15H

1*








17
16


18






15
13



1f3
If*


165






?00
?01

203


    K=I-JKQ
    PRINT 655,K«NnFP»SSZ««MStF
    IF (INDEX (11 ) ,FQ.3HYfcSi 1 BO. 210
    Pfi|NT ftfcfl
    READ 607,KO, JKDt'X (B> « INDEX (11)
    READ 608. (MStJpU) ,7=1. N0>
    PRINT 65?
    DC 157 o»l .NO
    KSMSUB („•) *JfQ
    RtnT ( J)=H(K)
    OC 158 „ = ! ,NO
    DC 158 K=i ,NO
    KK=NSUB(K| *.,MC
    CUnT ( J,K)=C I JJt«K)
    IF (INDEX (0) ,FO.->HYFS) 14tl3
                        i/ronrcn
    F=S*«AS/S?
    PHI^T 37.f«:lw(
    DC 15 I»2.MC
    CALL 6ALS«1 ( I .
    DC 16 JK = i ,1
    QF(JK)=0.
    DC 17 KLal .1
    QF(JK)=CP< JK)+CtNvC.fC.3HYES)20l«25fl
    DC 203 1»1 ,N
    DC 203 ,at,N
203 CCVAR(I,J)=C(I.J)«S2
    PRINT 651
    DC 205 IBI.-N
160
161
162
163
164
165
166
167
16«
169
170
171
172
173
17*
175
176
177
17P
179
ISO
1S1
IS?
183
1S4
1«5
186
Ifl7
iae
1R9
190
191
192
193
19*
195
196
197
198
199
POO
201
202
203
20*
?05
206
207
20fl
209
210
211
212
213
?1*
215
216
217

-------
131
001270
001307
001312
00131ft
001323
001325
001327
OOJ332
001334
001343
001344
001345
001345
001347
001351
0013?7
001364
001370
001172
001400
0014T3
001417
001424
001430
001432
001433
001435
00143ft
001451
0014=4
0014(3
001470
001473
001475
001510
001513
001520
001525
001927
001530
001532
001533
001546
0015=1
0015*0
001545
001572
001577
001603
001607
001610
001611
001614
001617
001621
001622
001625
001630
?05 PRINT 627. (COVAC (T. J) . J=l »Ni
PRINT h2R
PRINT FCRw?
??0 IF (INDF* (4) .FR.1HYFSlp51.300
?* 1 OF=FLOAI (M.N)
1 = 1
7=2 IF (TABLE < T , 1 ) -DF ) ?53 • ?S5 «254
?53 1=1+1
GC TO 25?
P = 4 IL=I-1
Xl=TAbL6 (TI..NPUP S9)
X? = TftBLt ( I .NR.'FCS)
Yl = TAtHL£ ( Tl.» 1 )
Y?=TABLE (T.I)
TE=Xl-(Yl-nF)«(vl_y2)/(Yl-Y?)
?*0 IF ( INDFIX (4 ) .FC. 1HYFS) ?S6»36n
?55 Tt = TABLE ( T ,Nfi|.F «:S)
?Sft DC 257 1 = 1 .A
Tl. IMssTF^SCPT (S'*C(l«T))
K= T - J^O
?=7 PRTN'T 614.^tH(TitTLT^
TOO TF(INUFX(c),f£--aHYFS)'aol» 35 n
101 PR TN T FO^
P»C 30b I J= 1 ,M
VARI (!J)=0.0
DC 303 WK=1 ,N
91 1 { JK) in.n
OC 302 *l = i ,^'
102 9L) ( JK) =» (K| « I Jl »r fKl. «.IK) «S> 1 ( JK)
103 91 ) ( JK)=?i 1 ( JK) «X ( JK . IJ)
DC 30 I ( T J ) +"5l- 1 ( JK )
1=7 IF (INUEX (4 ) .FC.iHYFS) 1*<0«25l
1*0 PRINT lft?H
PR INT FCHw?
SFOY=0.
5DFLY=0.
PRINT 72]
DC ISP 1=1. V
ntl. Y = Y ( I )-YhAT (T )
PCY=100.«nFl_V/Y ( I)
SCFLY = SCFLY + At»S (OFI y)
SFHYsSPCY* APS (COY)
TLTM=TE«SCOT (S?«V&-'T ( I) )
   210
   21S
   220
   2?1
   222
   2?3
   2?*
   225
   2?ft
   2?7
   22H
   2?9
   230
   231
   232
   233
   234
   235
   23*
   237
    243
    247
    ?4*
    249
    2^0
    251
    252
    253
    254
    255
    256
    257
    258
    259
    260
    2ftl
    262
    263
    264
    265
    266
    267

    268
    2ft9
    270
    271

    272
    273

-------
                                                                             132
 001636
 001656
 0016*2
 001662
 0016*6
 001670
 001674
 001676
 001705
 001711
 001716
 0017?3
 001T25
 0017*6
 0017=1
 0017*1
 0017.fl
0017*7
OOlTTi
002002
002004
OOP010
OOJ017
0020Z4
002047
002053
0020*3
002072
002074
002101
002103
0021J2
002125
0021,34
002140
002146
002155
002163
002170
002171
             61*,T.YHAT (I) tT|.IM,DEl Y«POY
       If (TYPE.FC^HSFk-ILOG) 3532. *s«3
       CCMTliMlJE
       PRTM  72»10.«*(YHAT-YLO«  .YUP(I) .YLOW(I) tDELTY 'I)
      PRINT  726
      PRt*T  7221 ,AVr>EI. YfCCNFAC
      CCMTINUF
      SPnY=SPDY/FLOAT (M)
      PRTNT  72?.
-------