v>EPA
Unrt»d StatW
Environmental Protection
Office of
Pwticidw ind Toxic Subm
Wuhington OC 20460
September 1985
Guidance for the
Reregistration of
Pesticide Products
Containing
Bentazon
as the Active Ingredient
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GUIDANCE FOR THE
REREGISTRATION OF PESTICIDE PRODUCTS
CONTAINING
BENTAZON
AS THE ACTIVE INGREDIENT
EPA CASE NUMBER: 182
ENVIRONMENTAL PROTECTION AGENCY
OFFICE OF PESTICIDE PROGRAMS
WASHINGTON, D.C. 20460
SEPTEMBER 1985
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TABLE OF CONTENTS
Page
Introduction 1
I. Regulatory Assessment 4
II. Requirement for Submission of Generic Data 29
III. Requirement for Submission of Product-Specific
Data 59
IV. Submission of Revised Labeling 63
A. Label Contents 63
B. Collateral Information 69
V. Instructions for Submission 69
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APPENDICES
Page
II-l Guide to Bibliography 73
II-2 Bibliography 75
II-3 FIPRA §3(c)(2)(B) Summary Sheet - EPA Form 8580-1 . . 95
II-4 Certification of Attempt to Enter Into an Agreement
with Other Registrants for Development of Data
EPA Form 8580-2 97
III-l Product Specific Data Report (End-Use Products) . . 98
IV-1 40 CFR 162.10 Labeling Requirements 99
IV-2 Table of Labeling Requirements Ill
IV-3 Physical/Chemical Hazards Labeling Statement. . . . 114
IV-4 Pesticide Storage Instructions 115
IV-5 Pesticide Disposal Instructions 115
IV-6 Container Disposal Instructions 12i
ii
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INTRODUCTION
The Federal Insecticide, Fungicide, and Rodenticlde Act
(FIFRA sec. 3(g)) directs EPA to reregister all pesticides as
expeditiously as possible.
To carry out this task, EPA has established the Regis-
tration Standards program, which will review all pesticide
products containing active Ingredients first registered before
January 1, 1977. Pesticides will be reviewed in use clusters
which have been ranked to give earliest review to pesticides
used on food and feed crops.
The Registration Standards program Involves a thorough
review of the scientific data base underlying pesticide
registrations and an identification of essential but missing
studies which may not have been required when the product
was initially registered or studies that are now considered
insufficient. EPA's reassessment results in the development
of a regulatory position, contained in a Registration Standard,
on each pesticide and its uses. The Agency may require the
registrant to modify product labels to provide additional
precautionary statements, restrict the use of the pesticide
to certified applicators, provide reentry intervals, modify
uses or formulation types, specify certain packaging limitations,
or other requirements to assure that proper use of the pesticide
will not result in adverse effects on the environment.
The scientific review, which is not contained in this
Guidance Package but is available from the National Technical
Information Service, concentrates on the technical grade of
the active ingredient and identifies missing generic data.
However, during the review of these'data we are also looking
for potential hazards that may be associated with the end use
(formulated) products that, p.ontain the active ingredient. If we
have serious concerns, we will address end use products as
part of the Registration Standards program and will propose
regulatory actions to the extent necessary- to protect the
public.
EPA has the authority under FIFRA sec. 3(c)(2)(B) to
require registrants to submit data that will answer our
questions regarding the hazard that may result from the
Intended use of a pesticide. Although sec. 3(c)(2)(B) provides
that all registrants are responsible for these data, the
Agency generally imposes generic data requirements only on the
registrants of the manufacturing use products (basic suppliers
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of the active ingredient) and other producers who do not
qualify for the formulator's exemption.*
A producer who wishes to qualify for the formulator's
exemption may change his source of supply to a registered
source, provided the source does not share ownership in
common with the registrant's firm. A registrant may do so
by submitting a new Confidential Statement of Formula, EPA
Form 8570-4, identifying the registered source of the active
ingredient, to the appropriate Product Manager within 90
days of receipt of this Guidance Document. The chart on the
following page shows what is generally required of those who
do ar.d do not qualify for the formulator's exemption in the
Registration Standards program.
If you decide to request the Agency to cancel the regis-
tration of any of your products subject to the requirements
of this Guidance Document, please notify the Product Manager
named in the cover letter, within 90 days from the receipt
of this document. If you decide to maintain your product
registration(s), you must provide the information described in
the following pages within the timeframes outlined. EPA will
issue a notice of Intent to cancel or suspend the registration
of any currently registered product which does not comply
with the requirements set forth in this Guidance Document.
You are reminded that FIFRA sec. 6(a)(2) requires you to
submit factual Information raising concerns of possible
unreasonable adverse effects of a pesticide. You should
notify the Agency of interim results of studies in progress
If those results show possible adverse effects.
•The formulator's exemption applies to a registrant of an
product if the source of his active ingredlent(s): (1) is a
registered product and (2) is purchased from a source which
does not have ownership in common with the registrant's
firm.
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PRODUCTS SUBJECT TO THE
REGISTRATION STANDARDS PROGRAM
ACTION(S) REQUIRED TO
MAINTAIN REGISTRATION
I. Products That Do Not Qualify
For The Formulator's Exemption
A. Single Active Ingredient
Products*
These products must be reregis-
tered. To obtain reregistration,
labeling, packaging and data
requirements must be satisfied
in accordance with the Regis-
tration Standards Guidance
Document.
B. Multiple Active Ingredient
Products
These products will not be
reregistered at this time. .
However, generic data required
to continue the registration of
the active ingredient under
review, as described in the
Registration Standards Guidance
Document, will be required and
some labeling precautions may
also be required.
II. Products That Do Qualify For
The Formulator1s Exemption
Only when additional restric-
tions or labeling are needed to
protect man or the environment
will these products be subject
to the Registration Standard
requirements. Affected products
will be dealt with in a variety
of ways, including but not
limited to the Label Improvement
Program and special intent
to cancel notices.
* End-use products of registrants who also produce a manufacturing-
use product will not be required to be reregistered provided that
registrant fulfills the requirements specified in the Guidance
Document for manufacturing-use product(s). Such end-use products
will be subject to the labeling changes required.for products in "II".
above. If there are no manufacturing-use products registered by any
company end-use products will be required to be reregistered.
INOTE: If all registrants in "I" above fail to meet the requirements in
JI-A and B above, then the registrants in "II" lose their right to
(qualify for the formulator's exemption and become subject to the
I requirements in I-A and B.
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I. REGULATORY ASSESSMENT
A. INTRODUCTION
This Registration Standard describes the regulatory position and rationale of
the Environnental Protection Agency (the "Agency") for all registered manufacturing-
use products (MPs) containing sodium bentazon as the sole active ingredient.*
This Standard also will require cetain changes on the labels of end-use products
(EPs) containing sodium bentazon. The Agency bases its position and rationale
on an evaluation of all MPs, and Section 3, 24(c), and Intrastate uses registered
for sodium bentazon. After briefly describing the chemical and Its uses, this
chapter presents the Agency's regulatory position and rationale, the criteria
for registration, acceptable.ranges and limits, labeling requirements, and the
current tolerances.
B. IESCRIPTION OP CHEMICAL
Bentazon Is the acceptable cannon name (approved by the Anerlcan National Standards
Institute and the Weed Science Science Society of America) for the herbicide
with the chemical name of 3-(l^thylethyl)-lH-2,l,3-benzothladiazln-4(3H)-one '
2,2-dioxide. The Chemical Abstracts Service (CAS) Registry number for bentazon
is 50723-80-3 while the EPA Office of Pesticide Program's Chemical Code Number •
Is 275200.
All products currently marketed In the U.S. contain the sodium salt of bentazon
as the active Ingredient, referred to as', sodium bentazon. Sodium bentazon MP is
marketed under the name "Bentazon Manufacturer's Concentrate". Sodium bentazon
single active Ingredient EP is marketed under the name "Basagran* Postemergence
Herbicide". A multiple active ingredient EP (mixture with atrazlne) is marketed
under the name "Laddock" Postemergence Flowable Herbicide". The EPA Office of
Pesticide Program's Chemical Code Number is 103901 for sodium bentazon.
The chemical formula for bentazon is CioH^N^ChjS and the molecular weight is
240.3* Pure analytical standard (i.e., purer than technical) bentazon is ttoite.
Technical grade bentazon (Isolated before formation of the sodium salt)
Is an odorless, non-volatile solid with a melting point of 137-139°C. Its
solubility (g/100 g solvent, 20°C) is 0.05 to water and 150.7 to acetone. Sodium
bentazon is considerably more soluble to water than bentazon, with a solubility
of 230 g/100 g to water.
Sodium bentazon is a post-emergence contact herbicide used to control selected
broadleaf weeds and sedges. It is applied by ground or air as a broadcast foliar
spray following weed emergence. Various tank mixes are also permitted. See the
EPA Index entry to this guidance package for additional label information, Including
the use sites for viiich sodium bentazon is registered.
C. Regulatory Position and Rationale
T. The available data do not Indicate that any of the risk criteria listed to
§ 162.U (a) of Title 40 of, the U.S. Code of Federal Regulations have been
met or exceeded for the uses of sodium bentazon at the present time. However,
substantial data gaps exist.
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Rationale:
(Note: Agency data requirements for reregistration are described in 40 CFR Part
158. The data tables in this guidance package relate these specifically
to bentazon and sodium bentazon.)
Hunan/Domestic Animal Hazard
Sodium bentazon belongs in Tbxlcity Category III (defined In 40 CFR 162.10)
based upon acceptable acute oral and acute dennal data. An acute Inhalation
study is supplementary (valid but does not meet EPA guideline requirements)
and will need to be repeated.
Subchronic data are supplementary (90-day rat feeding study and 13-week dog
study; bentazon) or invalid (21-day dennal study; sodium bentazon), and
will require.replacement. Compound-related effects were seen at 300 and
3000 ppm test levels in the dog study (numerous effects at 3000 ppm; prostatitis
at 300 ppm was basis of lowest-effect-level of 300 ppm and no-effect-level
of 100 ppm). A one year dog study is required for hazard assessment.
All chronic toxiclty data for bentazon are supplementary or Invalid, and
will require replacement. 24-month rat and 18-month mouse studies have been
invalidated, and a "for cause" laboratory audit requested, due to substantial
deficiencies. In a supplementary mouse oncogenlcity study, no specific
clinical or pathological symptoms could be associated with bentazon exposure.
A rat 3-generation reproduction study found no compound-related effects up
to a dietary level of 180 ppm. However, without effects at the highest dose,
the dose selection Is considered inadequate and an additional reproduction
study is required.
The available rat and rabbit teratogeniclty studies are Inadequate, but do
not suggest that bentazon is a potent teratogen or fetotoxlc agent. Terata
were observed In one rat study at a dose of 200 mg/kg/day, but the utility
and validity of these data are In question. Additional teratology studies
In the rat and rabbit are required.
A variety of mutagenlcity studies (analytical grade bentazon; or sodium
bentazon) have been reviewed, but none are adequate for regulatory purposes.
This is also the case for metabolism studies with labeled bentazon.
Ecological Effects
Technical bentazon Is considered slightly toxic to birds based on subacute
dietary testing. Formulated bentazon is considered slightly toxic to birds
based on acute oral testing with a 50* a.i. wettable powder. Avian reproduction
testing did not show effects up to the highest dietary level tested,
but the studies were found to lack vital Information and do not presently
meet EPA guideline requirements.
Technical bentazon is characterized by EPA as practically nontoxic to both
coldwater and wannwater fish, and slightly toxic to aquatic Invertebrates,
based on review of acute testing. Formulated bentazon is considered practically
nontoxic to coldwater and wannwater fish based on acute testing with a 48%
a.i. liquid product.
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Applications of sodium bentazon on registered use sites are considered unlikely
to result in acute hazard to most nontarget organisms because of the generally
low toxicIty seen In technical and formulated product testing, and low applicatl
rates. However, a final risk assessment is deferred due to lack of critical
environmental chemistry data and certain ecological effects data.
Biological opinions (covering all registered pesticides) have been received
from the U.S. Pish and Wildlife Service Office of Endangered Species (GES) for
three of the crops for which sodium bentazon is registered: corn, sorghun, and
soybeans. To avoid Jeopardy to the Valley Elderberry Longhorn Beetle (Desmoceru
californlcus dlmorriius), OES indicates that herbicides should be prohibited
iron designated areas In California In order to protect the host plant, elder-
berry (Sambucus spp.). Labeling developed by EPA to Implement this prohibition
Is Included in Section F below.
These~opinions also stated that "...to avoid Jeopardy to Solano grass...the use
of any herbicides toxic to graminoldes should be prohibited within..." certain
defined geographic areas of California, because of concerns with spray drift
and runoff from agricultural areas. Solano grass (Tuctorla (» Orcuttla)
mucrohata.) Is an endangered plant species found In a vernal lakebedi in Solano
County, California. Since no grass species are claimed on existing labeling "
to be controlled with sodium bentazon and the herbicide Is used on various
grass crops, Ecological Effects Branch (with Informal consultation with OES') did
not consider there to be a threat to Solano grass frcm the registered use of
this chemical.. Subsequently, information has been located indicating that
sodium bentazon may affect certain geminating grass species with direct
exposure at full dosage rates, but that It does not affect grasses after gennina
Solano grass germinates in March and April. The earliest planting date for
corn; sorghum, or soybeans Is for corn, which can be planted as early as April 1!
Since sodium bentazon is applied postemergence to the weeds, there may be
little opportunity for an application that could affect Solano grass.
Further consultation with CES will be Initiated. Label restrictions, as above,
and/or plant protection data requirements (under § 158.150) may be Imposed.
An oyster study and further envlronnental chemistry data are required, in
part, to evaluate whether there is any hazard to endangered mussel species
frcm sodium bentazon use.
". • ««
The Agency is not aware of any other data which would suggest that the risk
criteria of § 162.11 have been met or exceeded for the uses of sodium bentazon
at the present time.
2. The existing manufacturing-use pesticide product containing sodium bentazon as
the sole active ingredient may continue to be registered for sale, distribution,
reformulation, and use, subject to the terms and conditions specified In this
Standard. The registrant must provide or agree to develop the additional data
specified In Tables A and B of this guidance document to maintain the existing
MP registration or to permit new registrations of substantially similar sodium
bentazon MPs.
•••'•'• •£*•••-•;•",••••
Rationale t
There are substantial data gaps in support of existing sodium bentazon registra-
tions. The Agency has discretion to cancel or deny registrations because data
are missing or Inadequate. 'The Agency has elected to use the issuance of this
Standard as the mechanism for Identifying data needs. The Agency will complete
Its hazard evaluation, or determine what further data are necessary to do so,
upon review of the data being called In under this Registration Standard. The
Agency will determine at that time if such data will affect the registrations
of bentazon.
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If such review determines that criteria for determinations of unreasonable
adverse effects are met or exceeded (as specified under §162.11), a rebuttable
presumption shall arise that a notice of intent to cancel registration(s)
pursuant to FIPRA §6(b)(l) (or a notice of Intent to hold a hearing to determine
vtoether the registration(s) should be cancelled) may be issued. If, at any
time, review of the data indicates that an Imminent hazard (as defined by
FIFRA § 2(1)) is posed by bentazon use, Immediate suspension procedures may
be Initiated as per FIFRA. §6(c)(l).
3. The term TGAI (technical grade of the active ingredient) In the data tables
refers to the technical grade of bentazon, not sodium bentazon. On a case-
by-case basis, testing using sodium bentazon may be acceptable for fulfilling
TGAI testing requirements. Clarification or verification of all test materials
used in studies submitted by the registrant is required. The Agency reserves
the right to Impose additional testing of either bentazon or sodium bentazon
following review of this information and/or review of new studies submitted
to fulfill data gaps identified in this Standard.
Rationale;
Residue chemistry review has indicated that the moiety of concern (due to
detectable residues) is bentazon, not sodiun bentazon, and thus all tolerances
have been established for bentazon (combined with certain of its metabolites).
It is possible that, in addition to testing with bentazon, further testing
with sodium bentazon will be required to evaluate exposure specifically to
sodium bentazon. In many cases, the test material used in studies submitted
to the Agency is not fully identified, and it Is essential that this information
be submitted to enable assessment. Note that, In addition to testing with
TGAI, certain testing is specifically required using the MP (sodiun bentazon),
PAI (bentazon pure active Ingredient), PAIRA (pure active Ingredient, radiolabelled}
TEP (typical end-use product), and metabolites.
4
4. No new uses of sodiun bentazon will be permitted until the data base is adequate
to complete a hazard assessment.
Rationale;
In accordance with Conditional Registration Interim Final Regulations (FR
Vol. M, No. 93, May 11, 1979), no new uses or-new products may be registered
without "data sufficient to allow the Agency to determine that approval of
the application would not cause a significant Increase In the risk of unreasonable
adverse effects on the environment". For bentazon/sodium bentazon, the
entire subchronic and chronic toxicology data base (required to evaluate
hazard to humans/donestic animals from existing uses) is invalid or otherwise
Inadequate, and thus totally insufficient for evaluation of any new uses. The
Agency is unable to complete a tolerance reassessment of bentazon/sodium
bentazon because of these gaps, as well as residue chemistry data gaps.
The Agency is unable to fully assess potential human exposure, potential for
groundwater contamination, or conplete an ecological effects hazard assessment
of existing sodium bentazon uses because of exposure assessment/environmental
chemistry data gaps. There are also certain product chemistry," wildlife/aquatic
organism, and nontarget Insect data gaps that prevent full assessment of
existing use.
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5- The MP and EP manufacturer must make labeling changes specified in this guidance
document. These include grazing restrictions, a rotational crop restriction,
prohibition of sodium bentazon use where commercial crayfish or catfish
fanning are practiced, and restrictions regarding use of bentazon- or sodium
bentazon-contamlnated water for irrigation.
Rationale;
Residue chemistry review indicates a need for grazing restrictions for corn
and peanut forage to ensure residues are below established tolerance
levels of 3 ppm for these forage items at the tine of grazing.
To complete an exposure assessment, rotational .crop data, residue data on
crops receiving'irrigation water from sodium bentazon-treated rice fields,
and residue data on crayfish and catfish that are fanned in rice fields are
among the data required. Fending submission and review of this data, the
cited restrictions are required.
Ecological effects review specifies the modified/updated environmental hazard
statements as per Proposed Rule 40 CPR §156.55: Federal Register Vol. 49, No. If
September 26, 1984.
6. Based on review of available data, bentazon itself is not considered likely to
contaminate groundwater. However, data are required to determine the potential
for bentazon metabolites to contaminate groundwater. Bentazon does have the
potential to contaminate surface waters.
Rationale;
Review indicates that bentazon is very mobile In soil but that rapid degradation
is likely to prevent groundwater contamination. An aged leaching study is
needed to determine the potential for metabolites to contaminate groundwater.
Bentazon has the potential to contaminate surface waters because of 1) its
rice use pattern that Involves either direct application to water or application
to fields prior to flooding, and 2) runoff from treated areas for other uses.
D. CRITERIA FOR REGISTRATION UNDER THE STANDARD
To be covered under this Standard, products must contain sodium bentazon as
the sole active Ingredient, bear required labeling, and conform to the product
composition, acute toxicity limits, and use pattern requirements listed in
Section E of this document.
She applicant for registration or rereglstration of manufacturing-use products
subject to this Standard must comply with all terms and conditions described In
it, Including submission of an up-to-date Confidential Statement of Formula,
sutmisslon of revised labeling, comnitment to fill data gaps on the schedule
specified by the Agency and, when applicable, off er to pay compensation as
required by 3(c)(l)(D) and 3(c)(2)(D) of the Federal Insecticide, Fungicide
and Rodenticide Act (FIFRA), as amended, 7 U.S.C. 136(c)(l)(D) and 136(C)(2)(D).
Registration applicants must contact the Agency for specific Instructions,
including updated information on data requirements and companies whose data
have been used In support of registration.
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Registrants of end-use products who do not qualify for the flormulator's
Exanption must satisfy labeling, packaging, and data requirements In
accordance with this guidance package. Registrants of end-use products who
qualify for the Formula tor's Exanption must conply with the unique labeling
statements identified in Section P.
E. ACCEPTABLE RANGES AND LIMITS
1. Product Composition Standard
To be covered under this Standard, manufacturing-use products must
contain sodium bentazon as the sole active ingredient. Each MP
formulation proposed for registration must be fully described with
an appropriate certification of limits, stating maximum and minimum
amounts of the active Ingredient which may be present In products.
2. Acute Toxiclty Limits
The Agency will consider registration of manufacturing-use products
containing sodium bentazon, provided that the product labeling bears
appropriate precautionary statements for the acute toxicity category in
which each product is placed.
3. Use Patterns
To be registered under this Standard, manufacturing-use products
containing sodium bentazon may be labeled for formulation into end-use
products only for the ccranodities listed below. The attached Index
entry lists all registered uses, as well as approved maximum application
rates and frequencies.
-Terrestrial, non-donestlc, food uses: beans (dry or succulent),
Bohemian chili peppers, corn (field, sweet, or popcorn), grain
sorghum, peanuts, peas (dry or succulent), peppermint, soybeans,
speannint.
-Aquatic, non-dcmestic, food use: rice
-Terrestrial, non-domestic, non-food juse: established ornamental
turf (bahiagrass, bentgrass, bermudagrass, bluegrass, centlpedegrass
fescue, ryegrass-, St. AugustInegrass, zoysiagrass)
-Terrestrial, domestic, non-food use: established ornamental turf species
listed above.
LABELING
All MPs and EPs containing sodium bentazon must bear appropriate labeling as
specified In HO CFR §162.10. The guidance package for this Standard contains
Information on label requirements. All labeling changes must appear on all
products released for shipment by 9/86. All labeling changes must appear on all
products in channels of trade by 9/87.
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In addition, the following restrictions are required:
1. Manufacturing-Use Products
a) When citing the bentazon equivalent, the chemical name for bentazon
should be written as M3-(lHnethylethyl)-lH-2,l,3-benzothiadiazin-4(3H)-
one 2,2 dioxide11.
b) "Do not discharge effluent containing this product into lakes, streams,
ponds, estuaries,- oceans, or public waters unless this product is
specifically identified and addressed In a National Pollutant Discharge
Elimination System (NPDES) penult. Do not discharge effluent containing
this product to. sewer systems without previously notifying the sewage
treatment plant authority. For guidance, contact your State Water
Board or Regional Office of the U.S. Environmental Protection Agency."
2. End-Use Products
a) "Do not graze treated corn fields for at least 12 days after the
last sodium bentazon treatment.1*
b) "Do not graze treated peanut fields for at least 50 days after the -
last sodium bentazon treatment."
c) "Do not rotate crops used for food or feed, which are not registered
for use with sodium bentazon, on areas previously treated with this
chemical."
d) "Do not use sodium bentazon on rice fields In which the commercial
cultivation of catfish or crayfish Is practiced."
e) "Do not use water containing bentazon or sodium bentazon residues
from rice cultivation to irrigate crops used for food or feed unless
sodium bentazon is registered-for use on these crops."
f) For all uses except rice: "Do not apply directly to water or wetlands.
Do not contaminate' water by cleaning of equipment or disposal of wastes.
g) ' For rice use: "Do not contaminate water by cleaning of equipment or
disposal of wastes."
h) "Notice; It is a violation of federal laws to use any pesticide
In a manner that results In the death of an endangered species
or adverse modification of their habitat.
»
"The use of this product may pose a hazard to certain federally
designated endangered species known to occur In specific areas
within the CALIFORNIA counties of Merced, Sacramento, and
Solano. Before using this product in these counties you must
obtain the EPA Endangered Species Bulletin specific for these
areas. The bulletin (EPA/ES-85-8) is available from either your
County, Agricultural Extension Agent, the Endangered Species
Specialist In your State Wildlife Agency Headquarters, or the
Regional Office of the U.S. Fish and Wildlife Service (Portland,
Oregon). THIS BULLETIN MUST BE REVIEWED PRIOR TO PESTICIDE; USE.
THE USE OP THIS PRODUCT IS PROHIBITED IN THESE COUNTIES UNLESS
SPECIFIED OTHERWISE IN THE BULLETIN."
10
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1) Where bentazon equivalent is cited on the label, the chemical name
should be as in 1 (a) above.
TOLERANCES
m the IMited States, tolerances are currently established in 40 CPR §180.355
for
a) combined residues of bentazon (3-isopropyl-lH-2,l,3-benzothladlazln-4(3H)-
one-2,2-dioxide) and its 6- and 8-hydroxy metabolites in or on agricultural
commodities as follows:
Commodity parts per million
Beans (except soybeans), dried 0.05
Beans (exc. soybeans), dried, vine hays 3
Beans (exc. soybeans), forage 3
Beans, lima (succulent) 0.05
Beans, succulent 0.5
Bohemian chili peppers 0.5*
Com, fodder 3
Corn, forage 3
Corn, grain 0.05
Corn, fresh (incl. sweet K-KJWHR) 0.05
Mint 1
Peanuts 0.05
Peanuts, hay 3
Peanuts, hulls 0.3
Peanuts, forage 3
Peas (dried) 0.05
Peas (dried), vine hays 3
Peas, forage 3
Peas, succulent 0.5
Rice 0.05
Rice, straw 3
Sorghum, fodder 0.05
Sorghum, forage 0.20
Sorghum, grain 0.05
Soybeans 0.05
Soybeans, forage 3
Soybeans, hay 0.3
and
b) combined residues of bentazon (3-isopropyl-lH-2,l,3-benzothiadiazin-M(3H)-
one-2,2-dioxide) and its metabolite 2-amino-N-isopropyl benzamide in raw
agricultural commodities as follows:
Commodity Parts per
million
Cattle, fat 0.05
Cattle, mbyp 0.05
Cattle, meat 0.05
Eggs °'°5
Goats, fat 0.05
Goats, mbyp 0.05
Goats, meat 0.05
11
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(cont.)
Commodity parts per million
Hogs, fat 0.05
Hogs, mbyp 0.05
Hogs, meat 0.05
Milk 0.02
Poultry, fat 0.05
Poultry, mbyp 0.05
Poultry, meat 0.05
Sheep, fat 0.05
Sheep, mbyp 0.05
Sheep, meat 0.05
•The misprinted tolerance of 0.5 ppn for Bohemian chill peppers will be
corrected to read 0.05 ppm.
Tolerance reassessment cannot be conducted because of toxicology and
residue chemistry data gaps.
International Tolerances
There are 0.1 ppm Canadian tolerances for bentazon on soybeans, beans,
peas, corn, rice, and peanuts. Presently, there are no Mexican or
Codex Allmentarius tolerances for bentazon.
12
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EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT*
TYPE PESTICIDE; Herbicide
FORMULATIONS;
Tech (462)
F1C (1.66 Ib/gal)
SC/L (4 Ib/gal)
GENERAL WARNINGS AND LIMITATIONS; A selective herbicide for postemergence
control of certain broadleaf weeds and sedges* It is effective mainly
through contact action and foliar absorption. Rainfall or overhead irri-
gation within 8 hours after application may nullify its effectiveness.
Apply in 20 to 50 gallons of water per acre at 40 to 80 psi of pressure
with ground equipment; the higher rates are for use in dense crop or weed
foliage. Use a minimum of 5 gallons of water per acre and a maximum of
40 psi of pressure with aerial applications. Do not use flood, whirl
chamber, or controlled droplet applicator (CDA) nozzles. Do not cultivate
within 5 days before or after application in the following northern and
western states: AZ, CA, CO, CT, ID, IL, IN, IA, KS, KY, ME, MA, MI, MM,
MO, MT, NB, NV, NH, NJ, NY, ND, OH, OR, PA, RI, SD, UT, VT, WA, WV, WI,
WY. Do not apply to crops that have been subjected to stress conditions
such as hail damage, flooding, drought, injury from other herbicides, or
widely fluctuating temperatures, as crop injury may result. It may be
necessary to irrigate prior to application to ensure active weed growth;
weeds growing under drought conditions are usually not satisfactorily con-
trolled.
TIME REQUIRED FOR CONTROL; Not located.
PHYTOTOXICITY TO TARGET WEEDS; Not located.
PHYTOTOXICITY TO CROPS; Some leaf-speckling and leaf-bronzing may occur
under certain conditions.
MODE OF ACTION; Inhibition of 'photosynthesis and particularly, the Hill
reaction.
Livestock Tolerances; 0.02 ppm in milk; 0.05 ppm in eggs and in meat, fat
and meat byproducts of cattle, goats, hogs, poultry and sheep.
BROADLEAF WEEDS CONTROLLED;
Balloonvine (a)(c)
Bristly starbur (a)(c)(d)
Canada thistle (a)(b)(d)(f)(g)
Coffee senna (a)(c)
Common cocklebur (a)(c)(d)(e)(f)(g)
Common groundsel (b)
*Bentazon
3-isopropyl-lH-2,l,3-benzothiadiazin-4(3H)-one 2,2-dioxide (sodium salt)
Basagran
Issued: 6-28-85 1-103901-1
13
-------
EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT
BROADLEAF WEEDS CONTROLLED (continued)
PBDAEBA Common lambsquarters
PEDADBA Common purslane
PBFAEBA Common ragweed
PBFBUBA Common sunflower
PBGAFBM Cypressvine morningglory
PBEABAA Dayflower
PBFAOBE Devils beggarticks
PBGAFBV Entireleaf morningglory
PBGACBB Field bindweed
PBFBOAA Galinsoga
PBFAEBE Giant ragweed
PAUAEBA Gooseweed
PEWAIBG Hairy nightshade
PBGACBD Hedge bindweed
PCQBSBB Hemp sesbania
PBGAFBG Ivyleaf morningglory
PEWADBD Jimsonweed
PBDAIBA Kochia
PEAAGBP Ladysthumb
PBGAFBS Palmleaf morningglory
PEAAGBO Pennsylvania smartweed
PBGAFBU Pitted morningglory
PDAAJBF Prickly sida
PBGAFBT Purple morningglory
PCYABBA Redstern
PEYABBA Redweed
PBFDKAA Salsify
PBKAHBA Sheperdspurse
PBGAGBB Smallflower morningglory
PEAAGAD Smartweed
PDAACBA Spurred anoda
PBGAFBL ;, Tall morningglory
PBVAEBB Tropic croton
PDCABBA Unicorn-plant
PDAABBB Velvetleaf
PDAAEBC Venice mallow
PBFDBBF Western goldenrod
PEAAGBH Wild buckwheat
PBKBKBB Wild mustard
PBVAGBU Wild poinsettia
(a) in soybeans
(b) in mints
(c) in peanuts
(d) in corn and grain sorghum
(e) in rice
(f) in beans
(g) in peas
(aXcHd)
(a)(c)(dXe)
(aXcXd)
(aXcXd)
(aXdXf)
(aXdXf)
UXcXdXfXg)
(e)
CbXfXg)
(aXd)(f)
(a)
(aXc)
(aXc)(dXfXg)
(b)
CaXbXdXfXg)
(aXcXd)
CaXbXcXdXfXg)
(aXc)(d)
(aXcXdXfXg)
(aXcXd)
(e)
(aXe)
(b)
(aXfXg)
(aXcXd)
(e)
(aXcXd)
(aXcXd)
(a).(cXd)
(aXcXf)
UXcXdXf)
(aXd)
(b)
(aXd)
(aXbXdXfXg)
(a)
Issued: 6-28-85
1-103901-2
14
-------
EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT
GRASSES AND OTHER MONOCOTS CONTROLLED:
PBMAEBH Largespiked spikerush
PBMADBI Yellow nutsedge
(e)
(a) in soybeans
(b) in mints
(c) in peanuts
(d) in corn and grain sorghum
(e) in rice
(f) in beans
(h) in ornamental turf
AQUATIC WEEDS CONTROLLED:
PAEABBB Common waterplantain
PECACBB Ducksalad
PBMAGBG Ricefield bulrush
PBMAGBF River bulrush
PAEADAA Sagittaria
PBMADBF SmalIflower umbrella sedge
(e)
(e)
(i)
(i)
(e)
(i)
(e)
(i)
in rice
in CA rice
Issued: 6-28-85
1-103901-3
15
-------
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT
Tolerance, Use, Limitations
15001AA
15002AA
15003AA
TERRESTRIAL FOOD CROP
(Agricultural Crops)
Beans, Dry or Succu-
lent
0.75-1.0
(4 Ib/gal SC/L)
1.0-1.5
(4 Ib/gal SC/L)
0.05 ppm (beans, dry)
0.05 ppm (beans, lima (succulent))
0.5 ppm (beans, succulent)
3.0 ppm (beans, dry, vinehay)
3.0 ppm (beans, forage)
30 day preharvest interval in succulent beans.
Do not apply more than 2 pounds active ingredient
per acre in one season.
General Information; Do not apply to bean fields
until beans have at least the first trifoliate
leaf fully expanded because severe crop damage may
occur. Tolerant bean types are navy, pinto,
pinks, great northern, kidney, red, whites, cran-
berry, black turtle soup, small limas, large
limas, and snap beans.
Postemergence. Broadcast. Apply when weeds are
small and actively growing. Certain weed problems
may require the use of the higher dosage and re-
peat treatments, or the use of an oil concentrate.
The addition of oil may increase crop injury and
reduce yields.
Use limited to IL, IN, KY, MI, and OH. Postemer-
gence. Broadcast. For suppression of field and
hedge'bindweed. Apply with an oil concentrate
when the bindweed vines are a maximum of 10 inches
long.
Issued: 6-28-85
1-103901-4
16
-------
28005AA
Site, Dosage
and Formulation
(Ib a.i./A)
Corn
0.75-1.0
(4 Ib/gal SC/L)
EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT
Tolerance. Use. Limitations
0.05 ppm (grain)
0.05 ppm (fresh corn (including sweet corn kernel
plus cob with husk removed))
3.0 ppm (fodder and forage)
Do not apply more than 2 pounds active ingredient
per acre in 1 season.
General Information; Corn is tolerant at all
stages of growth, but applications generally cor-
respond to the corn growth stages of 1 to 5
leaves. Seed corn producers should consult toler-
ance of seed production inbred lines to bentazon.
Postemergence. Broadcast. Apply when weeds are
small and actively growing. Certain weed problems
may require the use of the higher dosage and re-
peat treatments, or the use of an oil concentrate.
0.50-0.75
(1.66 Ib/gal F1C)
(4 Ib/gal SC/L)
1.0-1.5
(4 Ib/gal SC/L)
1.0-1.5
(4 Ib/gal SC/L)
1.0-1.5
(4 Ib/gal SC/L)
Postemergence. Broadcast. Apply when weeds are
small and actively growing-. Do not'make more than
1 application per season. Oil concentrate must
be added to the spray mixture.
Formulated with or tank mixed with atrazine.
Use limited to all other than the following south-
ern states: AL, AR, FL, GA, LA, MS, NC, OK, SC,
TN, TX, VA. Postemergence. For partial control
of annual morningglories not larger than 4 true
leaves. Apply with an oil concentrate.
Use limited to IL, IN, KY, MI, and OH. Postemer-
gence. Broadcast.- For suppression of field and
hedge bindweed. Apply with an oil concentrate
when the bindweed vines are a maximum of 10 inches
long.
Postemergence. Broadcast. To provide partial
control of cocklebur where earlier treatments were
either not made or not successful. Use a thorough
spray coverage of cocklebur plants up to 24 inches
tall. Make a single application as shown, or ap-
ply 0.75 pound active ingredient per acre and re-
peat 10 to 14 days later.
Issued: 6-28-85
1-103901-5
17
-------
'28015AA
Site, Dosage
and Formulation
(Ib a.i./A)
Peanuts
0.75-1.0
(4 Ib/gal SC/L)
liO-1.5
(4 Ib/gal SC/L)
EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT
Tolerance. Use. Limitations
0.05 ppm (peanuts)
0.3 ppm (hulls)
3.0 ppm (forage and hay)
Do not apply more than 2 pounds active ingredient
per acre in 1 season.
General Information; Peanuts are tolerant at all
stages of growth, but applications generally cor-
respond to the peanut growth stages of bunching
to pegging.
Postemergence. Broadcast. Apply when weeds are
small and actively growing. Certain weed problems
may require the use of the higher dosage or repeat
treatments, or the use of an oil concentrate.
May be tank mixed with 4-(2,4-dichlorophenoxy)-
butyric acid, dimethylamine salt for postemergence
control of morningglories; or with acifluorfen
(except in OK and TX).
Postemergence. Broadcast. To provide partial
control of cocklebur where earlier treatments were
either not made or not successful, use a thorough
spray coverage of cocklebur plants up to 24 inches
tall. Make a single application, or apply 0.75
pound active ingredient per acre and repeat 10 to
14 days later.
/28074AA
Peas (dry or succu-
lent)
0.75-1.0
(4 Ib/gal SC/L)
0.05 ppm (peas, dry)
0.5 ppm (peas, succulent)
3.0 pptn (peas, dry, vinehay)
3.0 ppm (peas, forage)
Do not apply more than 2 pounds active ingredient
per acre in 1 season.
General Information; Peas are tolerant to benta-
zon after 3 pairs or leaves (or 4 nodes) are pre-
sent. Tolerant pea types are garden peas and
southern peas. Do not use on blackeyes grown in
CA or to garbanzo beans at any stage of growth,
as severe crop damage will occur. Do not add oil
to any bentazon application to peas.
Postemergence. Broadcast. Apply when weeds are
small and actively growing. Certain weed problems
may require the use of the higher dosage and re-
peat treatments.
Issued: 6-28-85
1-103901-6
18
-------
Site, Dosage
and Formulation
(Ib a.i./A)
/28012AA Peppermint
Spearmint
1.0-2.0
(4 Ib/gal SC/L)
/28072AA Rice
0.75-1.0
(4 Ib/gal SC/L)
0.75
(4 Ib/gal SC/L)
EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT
Tolerance, Use, Limitations
1 ppm (mint)
Do not apply more than 4 pounds active ingredient
per acre in 1 season.
Broadcast to established crops when weeds are
small and actively growing. Certain weed problems
may require the use of the higher dosage and re-
peat treatments, or the use of an oil concentrate.
0.05 ppm (rice)
3.0 ppm (straw)
Do not apply more than 3 pounds active ingredient
per acre in 1 season (maximum of 2 pounds active
ingredient per acre in first crop and 1 pound ac-
tive ingredient per acre in second ratoon crop).
General Information; Do not apply with ground
equipment when field is flooded because splashing
will wash the chemical off weed leaf surfaces and
minimize control. When making aerial applica-
tions, orient all nozzles straight down. Bentazon
may be used on the first and second (ratoon) crop.
Early postemergence. Broadcast. In an alternate
flooding culture, apply when there is not water
on the field and at least 24 hours prior to flood-
ing. The weed growth stages at this time general-
ly correspond to*rice that is tillering (stool-
ing). In a continuous flooding culture or when
treating after permanent flood, apply when weeds
are above the surface of the water. For early
treatment, water may be partly or completely
drained to expose more w,eed growth. Do not raise
water level for at least 24 hours after applica-
tion. In CA add nonphytotoxic oil (containing
emulsifier) to the spray mixture.
Postemergence. Tank mix with 3* ,4'dichloropro-
pionanilide for control of mixed populations of
grasses and broadleaf weeds. Apply by ground or
air to drained fields only. Do not apply on the
second (ratoon) crop.
Issued: 6-28-85
1-103901-7
19
-------
'28019AA
Site, Dosage
and Formulation
(Ib a.i./A)
Sorghum, Grain
'28023AA
0.75-1.0
(4 Ib/gal SC/L)
0.5-0.75
(4 Ib/gal SC/L)
Soybeans
0.75-1.0
(4 Ib/gal SC/L)
1.0-1.5
(4 Ib/gal SC/L)
EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT
Tolerance. Use. Limitations
0.05 ppm (grain, fodder)
0.2 ppm (forage)
Do not apply more than 1 pound active ingredient
per acre in 1 season.
Do not apply to grain sorghum that is heading or
blooming.
General Information; Grain sorghum is tolerant
at all stages of growth up to and including early
boot stage, but applications generally correspond
to the crop growth stages of 1 to 5 leaves.
Posternergenee. Broadcast. Apply when weeds are
small and actively growing. Certain weed probleas
may require the use of the higher dosage or the
addition of an oil concentrate.
Postemergence. Broadcast. Apply when weeds are
small and actively growing. Do not make more than
1 application per season. An oil concentrate must
be added to the spray mixture. Tank mix with
atrazine.
0.05 ppm (soybeans)
0.3 ppm (hay)
3.0 ppm (forage)
Do not apply more than 2 pounds active ingredient
per acre in 1 season.
General Information; Soybeans are tolerant to
bentazon at all stages of growth, but applications
generally correspond to the growth stages of uni-
foliate to 2 expanded trifoliate leaves.
May be tank mixed with, or applied sequentially
to sethoxydim; or aciflubrfen, or sethoxydim and
acifluorfen. The determination of tank mix or
sequential application should be made by the stage
of the weeds being controlled by each chemical.
Postemergence. Broadcast. Apply when weeds are
small and actively growing. Certain weed problems
may require the use of the higher dosage and re-
peat treatments, or the use of an oil concentrate.
Use limited to all other than the following south-
ern states: AL, AR, FL, GA, LA, MS, NC, OK, SC,
TN, TX, VA. Postemergence. For partial'control
of annual momingglories not larger than 4 true
leaves. Apply with an oil concentrate.
Issued: 6-28-85
1-103901-8
20
-------
Site, Dosage
and Formulation
(Ib a.i./A)
EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT
Tolerance, Use, Limitations
Soybeans (continued)
1.0-1.5
(4 Ib/gal SC/L)
1.0-1.5
(4 Ib/gal SC/L)
0.75-1.0
(4 Ib/gal SC/L)
Spearmint
Use limited to IL, IN, KY, MI, and OH. Postemer-
gence. Broadcast. For suppression of field and
hedge bindweed. Apply with an oil concentrate
when the bindweed vines are a maximum of 10 inches
long.
Postemergence. Broadcast. To provide partial
control of cocklebur where earlier treatments were
either not made or not successful, use a thorough
spray coverage of cocklebur plants up to 24 inches
tall. Make a single application, or apply 0.75
pound active ingredient per acre and repeat 10 to
14 days later.
Postemergence. Broadcast. Tank mix with 4-(2,4-
dichlorophenoxy)butyric acid, dimethylamine salt
for postemergence control of morningglories. Ap-
ply when weeds are actively growing and before
annual morningg lory vines are a maximum of 6 inch-
es long in the south (AL, AR, FL, GA, LA, MS, NC,
OK, SC, TN, TX, VA) and a maximum of 10 inches
long in all other states. Do not add oil to the
tank mix. Do not make more than 1 application of
the tank mix per season.
See Peppermint cluster.
'33015AA
'33016AA
'33017AA
'33019AA
'33023AA
'33031AA
'33049AA
'33050AA
'33056AA
TERRESTRIAL NON-FOOD CROP
(Ornamental Plants and Forest Trees)
Bahiagrass
Bentgrass
Bermudagrass
Bluegrass
Centipedegrass
Fescue
Ryegrass
St. Augustinegrass
Zoysia Grass
1.0-2.0
(4 Ib/gal SC/L)
Issued: 6-28-85
Broadcast. Yellow nutsedge control. Apply to es-
tablished turf when yellow nutsedge is actively
growing under good soil moisture conditions. If
desired control is not obtained with the first ap-
plication, make additional applications at inter-
1-103901-9
21
-------
EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT
Site, Dosage Tolerance, Use, Limitations
and Formulation
(Ib a.i./A)
Bahiagrass cluster (continued)
vals of 10 to 14 days. Do not apply more than 3
pounds active ingredient per acre in any 1 sea-
son* Flan the initial application for when most
yellow nutsedge has emerged. In unmowed turf,
make first application after yellow nutsedge emer-
gence but before it is 8 inches tall. Do not mow
3 to 5 days before or after application. Do not
apply to golf course greens or collars. Avoid
over-the-top spraying of adjacent ornamentals.
Spraying near the base of established ornamentals
should not result in injury.
AERIAL AND TANK MIX APPLICATIONS
9001500 Aerial Application
aAAAAAA
Refer to
TERRESTRIAL FOOD CROP
(Agricultural Crops)
All Sites
9900300 Tank Mix
aAAAAAA
— Refer to
TERRESTRIAL FOOD CROP
(Agricultural Crops)
Corn, Peanuts, Rice, Sorghum. Soybeans
Issued: 6-28-85 1-103901-10
22
-------
EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT
Listing of Registered Pesticide Products by Formulation
i046.0001 46% technical chemical
bentazon, sodium salt (103901)
007969-00042
ilOl.6614 1.66 Ib/gal flovable concentrate
bentazon, sodium salt (103901) pLus atrazine (080803)
007969-00054
i!04.0015 4 Ib/gal soluble concentrate/liquid
bentazon, sodium salt (103901)-
007969-00045
Issued: 6-28-85 1-103901-11
23
-------
EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT
Appendix A
Listing of Common Chemical Names Used on the Entry
Chemical Common Name . EPA Acceptable
Code (source) Common/Chemic al~Name
121001 sethoxydim (ISO) 2-[l-(ethoxyimino)butyl]-5-[2-(ethylthio)-
propyl]-3-hydroxy-2-cyclohexen-l-one
Issued: 6-28-85 1-103901-12
24
-------
'EQABBA
'BFABBB
'BFAWBB
'CQAMBG
'BFDQBD
?BFCXBK
'BDAEBA
>EDADBA
'BFAEBA
'BFBUBA
'BGAFBM
'BEABAA
'BFAOBE
'BGAFBV
'BGACBB
'BFBOAA
'BFAEBE
'AUAEBA
>EWAIBG
'BGACBD
ttQBSBB
'BGAFBG
'EWADBD
'BDAIBA
'EAAGBP
'BGAFBS
?EAAGBO
'BGAFBU
'DAAJBF
?BGAFBT
'CYABBA
5EYABBA
?BFDKAA
?BKAHBA
PBGAGBB
PEAAGAD
?DAACBA
PBGAFBL
?BVA£BB
PDCABBA
PDAABBB
PDAAEBC
PBFDBBF
PEAAGBH
PBKBKBB
?BVAGBU
EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT
Appendix B
Listing by Site/Pest and Site/Formulation/Registration Number
BROADLEAF WEEDS CONTROLLED:
Balloonvine
Bristly starbur
Canada thistle
Coffee senna
Common cocklebur
Common groundsel
Common lambsquarters
Common purslane
Common ragweed
Common sunflower
Cypressvine morningglory
Dayflower
Devils beggarticks
Entireleaf morningglory
Field bindweed
Galinsoga
Giant ragweed
Gooseweed
Hairy nightshade
Hedge bindweed
Hemp sesbania
Ivyleaf morninglory
Jimsonweed
Kochia
Ladysthumb
Palmleaf morningglory
Pennsylvania smartweed
Pitted morningglory
Prickly sida
Purple morningglory
Redstem
Redweed
Salsify
Sheperdspurse
SmalIflower morningglory
Smartweed
Spurred anoda
Tall morningglory
Tropic croton
Unicorn-plant
Velvetleaf
Venice mallow
Western goldenrod
Wild buckwheat
Wild mustard
Wild poinsettia
Issued: 6-28-85
1-103901-13
25
-------
?BMAEBH
PBMADBI
EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT
Appendix B
Listing by Site/Pest and Site/Formulation/Registration Number (continued)
GRASSES AND OTHER MONOCOTS CONTROLLED;
Largespiked spikerush
Yellow nutsedge
AQUATIC WEEDS CONTROLLED;
PAEABBB Common vaterplantain
PECACBB Ducksalad
?BMAGBG RicefieId bulrush
?BMAGBF River bulrush
PAEADAA Sagittaria
PBMADBF Smallflower umbrella sedge
/15001AA
/15002AA
/15003AA
/28005AA
/28015AA
/28074AA
TERRESTRIAL FOOD CROP
(Agricultural Crops)
Beans, Dry or Succulent
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
Corn
Pest (see lists above)
(1.66 Ib/gal F1C)
007969-00054
(4 Ib/gal SC/L)
007969-00045
Peanuts
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
Peas (dry or succulent)
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
Issued: 6-28-85
1-103901-14
26
-------
EPA Compendium of Acceptable Uses
BENTAZON, SODIUM SALT
Appendix B
Listing by Site/Pest and Site/Formulation/Registration Number (continued)
/28012AA Peppermint
Spearmint
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
.'2807 2AA Rice
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
'28019AA Sorghum, Grain
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
'28023AA Soybeans
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
TERRESTRIAL NON-FOOD CROP
(Ornamental Plants and Forest Trees)
'33015AA Bahiagrass
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
'33016AA Bentgrass
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
•
'33017AA Bermudagrass
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
'33019AA Bluegrass
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
Issued: 6-28-85
1-103901-15
27
-------
EPA Compendium of Acceptable Uses
BENTA20N, SODIUM SALT
Appendix B
Listing by Site/Pest and Site/Formulation/Registration Number (continued)
'33023AA Centipedegrass
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
'33031AA Fescue
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
33049AA Ryegrass
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
33050AA St. Augustinegrass
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
33056AA Zoysia Grass
Pest (see lists above)
(4 Ib/gal SC/L)
007969-00045
Issued: 6-28-85
1-103901-16
28
-------
REQUIREMENT FOR SUBMISSION OF GENERIC DATA
A. This portion of the guidance document is a Notice
issued under the authority of PIPRA sec. 3(c)(2)(B). The
tables following this section list the data required for
maintaining the registrability of each product.
EPA has determined that additional generic data described
in Table A must be submitted to EPA for evaluation in order
to maintain in effect the registration(s) of your product(s)
identified as an attachment to the cover letter accompanying
this guidance document. As required by PIPRA sec. 3(c)(2)(B),
you are required to take appropriate steps to comply with
this Notice.
. EPA may suspend the registration of each of those products
unless, within the specified time, you have informed EPA how
you will satisfy the requirements of this Notice. Any such
suspension will remain in effect until you have complied with
the terms of this Notice.
B. What Generic Datal/ Must be Submitted. You may deter-
mine which generic data you must submit by consulting Table A
at the end of this chapter. That table lists the generic
data needed to evaluate the continued registrability of all
products, and the dates by which the data must be submitted.
The required studies must be conducted in accordance with
EPA approved protocols (such as those contained in the Pesticide
Assessment Guidelines 2/ or data collected under the approved
protocols of the Organization for Economic Cooperation and
Development (OECD). If you do not wish to develop data
in support of certain uses appearing in your labeling, you
may delete those uses at the time you submit your revised
labeling. ^
For certain kinds of testing (generally ecological
effects), EPA requires the test substance .to be a "typical
formulation," and in those cases EPA needs data of that type
I/ Generic data pertain to the properties or effects of a
particular Ingredient, and thus are relevant to an evaluation of
the risks of all products containing that ingredient, regardless
of the product's unique composition or specific use. Product-
specific data relate only to the properties or effects of a
product with a particular composition (or a group of products
with closely similar composition).
2/ The Pesticide Assessment Guidelines are available-in hard
copy or microfiche from the National Technical Information
Service, 5285 Port Royal Road, Springfield, Va. 22161.
29
-------
for each major formulation category (e.g., emulsifiable concen-
trates, wettable powders, granulars, etc.) These are classified
as generic data and when needed are specified in Table A.
EPA ir.ay possess data on certain "typical formulations" but
not others. Note; "Typical formulation" data should not be
confused with product-specific data (Table B) which are
required on each formulation. Product-specific data are
further explained in Chapter III of this document.
C. Options Available for Complying With Requirements
to Submit Data
Within 90 days of your receipt of this' Notice you must
'submit to EPA a completed copy of the form entitled "PIPRA
Section 3(c)(2)(B) Summary Sheet" [EPA Form 8580-1, Appendix
11-33 for each of your products. On that form you must state
which of the following methods you will use to comply with
the requirements of this Notice:
1. (a) Notify EPA that you will submit the data, and
(b) either submit the existing data you believe will
satisfy the requirement, or state that you will generate
the data by conducting testing. If the test procedures
you will use deviate from (or are not specified in) the
Pesticide Assessment Guidelines or protocols contained in
the Reports of Expert Groups to the Chemicals Group,
Organization for Economic Cooperation and Development
(OECD) Chemicals Testing Programme, you must enclose the
protocols you will use.
OR
2. Notify EPA that you have entered Into an agreement
with one or more other registrants to Jointly develop (or
share in the cost of developing) the data. If you elect
this option, you must notify EPA-which registrant(s) are
parties to the agreement.
OR
3. Pile with EPA a completed "Certification of Attempt to
Enter Into an Agreement With Other Registrants for Develop-
ment of Data" (EPA Form 8580-6, Appendix II-4)*/
V PIPRA sec. 3(c)(2)(B) authorizes Joint development of
data by two or more registrants, and provides a mechanism by
which parties can obtain an arbitrator's decision if they agree
to Jointly develop data but fail to agree on all the terms of
the agreement. The statute does not compel any registrant to
agree to develop data Jointly.
(Footnote continued on next page)
30
-------
OR
b. Request that EPA amend your registration by deleting
the uses for which the data are needed. (This option is
not available to applicants for new products.)
OR
5. Request voluntary cancellation of the registration(s)
of your products for which the data are needed. (This option
is not available to applicants for new products.)
D« Procedures for Requesting Changes in Testing Methodology
and Extensions of Time— ajL
EPA recognizes that you may disagree with our conclusions
regarding the appropriate ways to develop the required data
or how quickly the data must be submitted. If the test
procedures you plan to use deviate from (or are not specified
in) the registration guidelines or protocols contained in
the reports of the Expert Groups to the Chemical Groups,
Organization for Economic Cooperation and Development (OECD)
Chemicals Testing Programme, you must submit the protocol
for Agency review prior to the Initiation of the test.
If you think that you will need more time to generate the
required data than Is allowed by EPA's schedule, you may
submit a request for an extension of time. The extension
request must be submitted in writing to the Product Manager.
(Footnote continued from previous page)
In EPA's opinion, Joint data development by all regis-
trants subject to a data requirement or a cost-sharing agreement
among all such registrants is clearly in the public interest.
Duplication of testing could increase costs, tie up testing
facilities, and subject an unnecessarily large number of
animals to testing.
As noted earlier, EPA has discretion to suspend the
registration of a product when a registrant falls to submit data
required under PIPRA Section 3(c)(2)(B). EPA has concluded that
It should encourage Joint testing rather than duplicatlve
testing, and that suspension should be withheld in certain cases.
to further this goal. Accordingly, If (1) a registrant has
informed us of his intent to develop and submit data required
by this Notice; and (2) a second registrant informs EPA that
it has made a bona fide offer to the first registrant to share
in the expenses of the testing [on terms to be agreed upon
or determined by arbitration under PIFRA Section 3(c) (2)(B)(ill)];
and (3) the first registrant has declined to agree to enter
into a cost-sharing agreement, EPA will not suspend the
second firm's registration.
31
-------
The extension request should state the reasons why you believe
that an extension Is appropriate. While EPA considers your
request, you must strive to meet the deadline for submitting
the required data.
32
-------
TABUS A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
Guideline Citation and Test
Name of Test Substance
§158.120 Product Chemistry
Product Identity:
61-2 - Description of Beginning Materials
and Manufacturing Process
61-3 - Discussion of Formation of
Impurities
Analysis and Certification of Product
Ingredients
62-1 - Preliminary Analysis
Physical and Chemical Characteristics
63-2 - Color
63-3 - Physical State
63-4 - Odor
63-5 - Melting Point
63-6 - Boiling Point
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
TGAI
Guidelines
Status
R
R
CR
R
R
R
R
R
Are Data Footnote
Required Number
Yes No
OP
m
o
O
O
O
n
n 2
n 2
n 2
on
oa
oa
oa
oa
Data Must Be
Submitted Within
Time Frames Listed
Below V.
6 months
6 months
12 months
33
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
Guideline Citation and
Name of Test
Test Guidelines
Substance Status
Data must Be
Are Data Footnote Submitted Within
Required Number Time Frames Listed
Yes No Below 1L
§158.120 Product Chemistry (Continued)
63-7
63-8
63-9
63-10
63-11
63-12
63-13
Other
64- 1
- Density, Bulk Density, or
Specific Gravity
- Solubility
- Vapor Pressure
- Dissociation constant
- Octanol/water partition
coefficient
- pH
- Stability
Requirements:
I/
- Sutmlttal of samples
TOAI R
TGAI or PAI R
PAI R
PAI R
PA? R
TGAI R
TGAI R
TGAI, PAI CR
[X]
o
n
QD
n
n
C ]
[3D
m
n
n
n
cm
n
6 months
6 months
6 months
6 months
TGAI » Technical Grade of the Active Ingredient; PAI « Pure Active Ingredient; R » Required; CR - Conditionally Required
\l Data must be submitted within the indicated time frame, based on the date of the Guidance Document.
0 6 Month Due Date is 07 ^AR IQRp .
2/ Update as per current product chemistry guidelines (Subdivision D).
3/ The Agency will request samples if /when needed. If requested, the time permitted for subnittal will be 6 months.
34
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
§158.125 Residue Chemistry
171-2 - Chemical Identity TGAI partially
171-3 - Directions for Use — partially
171-4 - Nature of Residue (Metabolism)
- Plants PAIRA partially
00010517, 00051652,
00039657, 00051653,
00106221, .00051655,
00106230, 00040516,
00108281, 00039852,
00052052, 00052050,
00039282, 00051656,
00010518, 00039285,
00039284, 00039283,
00039656, 00039668,
00039666, 00039671,
00039661, 00039660,
00039664, 00039670,
00039672, 00039280,
00039669, 00051654,
00039665, 00039281,
00039667, 00040519,
00039659, 00040184,
00039852, 00039278,
00040188, 00084714,
00039279, 00052055,
00084715
3/
yes 6 months
I/ -
yes 6 months
5A/
yes 18 months
- Animals
PAIRA and Plant
Metabolites
35
7,8/
partially
yes
18 months
Cows
155039850, 00044781,
00039851, 00040110,
00039848, 00039849,
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
Data Requirements
Conpositlon"
Does EPA Have Data
To Satisfy This
I/ Requirement? (Yes,
No, or Partially)
Bibliographic
Citation
§158.125 Residue Chemistry - Continued
Goats
00039853, 00039854,
00039818, 00040111,
Poultry
00039856, 00011782,
00039848, 00039855,
00039857,
Swine
00137904
Laboratory Animals
Rat
00051652, 00039848,
00039853, 00040111,
00063615
Rabbit
00039861, 00039860
Mice
00039862
Must Additional Data
Be Submitted Under
PIPRA § 3(c)(2)(B)?
Time Frames For Data
Submission 2/
36
-------
TABIE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
Data Requirement
Does EPA Have Data
To Satisfy This
I/ Requirement? (Yes,
Composition No or Partially)
Bibliographic
Citation
Must Additional Data
Be Submitted Under
PIPRA § 3(c)(2)(B)?
Time Frames for Data
Submission 2/
§158.125 Residue Chemistry - Continued
171-4 - Residue Analytical Method
- Plant residues
TGAI and Metabolites
yes
- Animal residues
171-4 - Storage stability
TGAI and Metabolites partially
yes
171-4 - Magnitude of the Residue-
Residue Studies for Each Food Use -
- Crop Group #1 - Legune Vegetables (Succulent or Dried)
o Soybeans
— Crop field trials TEP yes
— Processed Pood/Peed
EP
yes
(plant and animal)
00051657, 00106263,
00023509, 00040521,
00039851, 00014782,
00039658, 00040522,
00040185, 00040517,
00040186, 00040187,
00040785
incl. above
00039290, 00040189
00040193
(crop and
00106228,
00040182,
00040181,
00079082,
00040174,
00031796,
00106263,
00023507,
00040173,
00040184
37
processed)
00040172,
00040177,
00040176,
00040180,
00051658,
00040183,
00040178,
00040179,
00040186,
9/
reserved
9,107
yes 15 months
9/
reserved
reserved
9/
reserved
9/
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
Must Additional bata
Be Submitted Under
PIPRA § 3(c)(2)(B)7
Time Frames for Data
Submission £/
Data Requirement
Composition"
Does EPA Have Data
To Satisfy This
I/ Requirement? (Yes,
No or Partially)
Bibliographic
Citation
§158.125 Residue Chemistry - Continued
o Beans, succulent and dried
Beans, succulent (except lima beans)
— Crop Field Trials TEP
Processed Food/Feed
EP
yes
no
00106213, 00106263,
00023507, 00026208,
/
reserved
yes
24 months
Beans, dried
— Crop Field Trials
Beans, lima
— Crop Field Trials
o Peas, succulent and dried
Peas, succulent
-- Crop Field Trials
Peas, dried
— Crop Field Trials
TEP
TEP
TEP
TEP
yes
yes
yes
partially
00106243, 00106263,
00040520, 00023507,
00106231, 00023507,
00106263, 00051911,
00040520
00106263, 00051912,
00040521, 00023507,
00040520, 00106243
00051912
reserved
9/
reserved
9/
9/
reserved
9.12/
yes 18 months
38
-------
TABIE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
Data Requirement
Does EPA Have
Data To Satisfy
I/ This Require-
Conposltlon ment? (Yes, No
or Partially)
Bibliographic
Citation
Must Additional Data
Be Submitted Under
PIPRA § 3(c)(2)(B)?
Time Frame for
Submission*?/
§158.125—Residue Chemistry, cont.
Crop Group #2—Foliage of Legume Vegetable Group
o Soybean forage
— Crop Field Trials TEP
o Soybean hay
— Crop Field Trials
o Bean forage and nay
— Crop Field Trials
o Pea Forage and Vine Hay
— Crop Field Trials
Crop Group 03—Fruiting Vegetable
Group (except cucurbits)
o Bohemian chill peppers
— Crop Field Trials
TEP
TEP
TEP
partially
yes
yes
yes
00010183, 000*10176,
00079082, 00051658,
00106227,
00079082, 00010183,
00031796, 00051658,
00106236, 00106228,
000519H, 00106236,
00106231, 00106213,
00010521, 00051912,
TEP
yes
00106215
9,13/
yes 18 months
reserved
9/
reserved
i/
00106213, 00051912, reserved"
9/
reserved
s/
39
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
Does EPA Have
Data To Satisfy
I/ Otils Require- Bibliographic-
Data Requirement Composition" merit? (Yes, No Citation
or Partially)
§158.125 Residue Chemistry - Continued
Crop Group M—Cereal Grains Group
o Conij grain
— Crop Field Trials TEP yes
— Processed Food/Feed EP yes
o Corn^ fresh (Incl. sweet corn)
— Crop Field Trials TEP yes
— Processed Food/Feed EP no
o Rice, grain '
— Crop Field Trials , TEP yes
(crop and processing)
00023507, 00106252
00023508, 00106254
00106263, 00106251
00023511, 00108303
00023511, 00106238
00106253, 00040171
(crop and processing)
00106238, 00010831,
00010829, 00040820,
00040822, 00040819,
00040833, 00052053,
00040824, 00040834,
00040828, 00040823,
00040832, 00040830,
00040825, 00040821,
00084711, 00040824,
Must Additional Data
Be Submitted Under
FIFRA § 3(c)(2)(B)7
Time Fr
Submit on 2/
I/
reserved
reserved
J1
reserved
reserved"
JJ
reserved
— Processed Food/Feed
o Sorghum, grain
— Crop Field Trials
— Processed Food/Feed
EP
TEP
EP
yes
yes
no
Incl. above
00126689
9/
reserved
i/
reserved
i/
reserved
-------
TABLE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
Data Requirement
Composition"
Does EPA Have
Data To Satisfy
I/ Tills Require-
ment? (Yes, No
or Partially)
Bibliographic
Citation
Must Additional Data
Be Submitted Under
PIPRA § 3(c)(2)(b)?
Time Frame for
Submission?/
§158.125 Residue Chemistry, cont.
Crop Group #5—Forage, Fodder,
and Straw of Cereal Grains
Group
o Corn forage and fodder
— Crop Field Trials
o Rice straw
— Crop Field Trials
o Sorghum fodder and forage
— Crop Field Trials
Miscellaneous.Crops Not Included
In Any Crop Grouping
o Peanuts (kernels)
— Crop Field Trials
— Processed Food/Feed
TEP
yes
TEP
yes
TEP
yes
TEP
EP
yes
yes
00106254, 00106252
00106253, 00106251,
00040171, 00106238,
00108303, 00023511,
00106263
00010833,
00106238,
00010834,
00052053,
00040823,
00040827,
00040829,
00126689
00040825,
00040821,
00040822,
00040820,
00040831,
00040832,
00040829
(crop and processing)
00106263, 00023507,
Q0106237, 00023511,
Incl. above
9/
reserved
reserved
9/
reserved
9/
reserved
9/
reserved'
9/
-------
10
TABLE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BEMTAZON
*
Data Requirement
§158.125 Residue Chemistry, cont.
o Peanut hulls
— Crop Field Trials
o Peanut forage and hay
— Crop Field Trials
o Mint
— Crop Field Trials
— Processed Food/Feed
Magnitude of Residue In Meat, Milk
Poultry, Eggs
Food Handling
171-5 - Reduction of Residue
2p_/
171-6 - Proposed Tolerance
Does EPA Have Must Additional Data
Data To Satisfy Be Submitted Under
I/ This Require- Bibliographic FIFRA § 3(c)(2)(b)7
Composition"" ment? (Yes, No Citation TJjne Frame for
or Partially) Submission2/
TEP yes
TEP yes
TEI* yes
EP yes
TGAI or Plant yes
Metabolites
18/
EP N/A
Residue of
Concern
Residue of
Concern yes
00023511, 00106237
00106237, 00023511
(crop and processing)
00023511, 00106211,
00106263, 00023507
00108303, 00039819,
00039856, 00039855,
00039811, 00137901
see 171-1
I/
reserved
I/
reserved
i/
reserved
reserved"
IV
reserved
no
19/
yes 9 months
21/
reserved
171-7 - Reasonable Grounds In
Support of Petition
171-13 - Subnittal of Analytical
Reference Standards22
PAIRA
42
-------
11
TABLE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
Data Requirement
Composition"
Does EPA Have
Data To Satisfy
I/ This Require-
ment? (Yes, No
or Partially)
Bibliographic
Citation
Must Additional Data
Be Submitted Under
PIPRA § 3(c)(2)(b)?
Time Frame for
Submission^/
§158.125 Residue Chemistry, cont.
I/ Composition: TOAI - Technical grade of the active Ingredient; PAIRA
Typical end-use product; EP « End-use product.
Pure active Ingredient, radlolabelled; TEP =
thin Ah^r^fUsAted
21 Data must be submitted within i^olnd^Sftted time frame, based on the date of the Guidance Document.
0 6 Month Due Date is 2 <
0 15 Month Due Date Is
0 18 Month Due Date is
0 21 Month Due Date is
3/ See Product Chemistry Table (61-2 and 62-3).
V A restriction against grazing Is required for at least 12 days after the last treatment of corn f orage/f odder.
A 50-day grazing restriction Is required for peanut forage and hay.
J5/ The residues in plants, not extractable with MeCH and composing 50-67/t of total, should be better characterized.
. 6/ The 6-hydroxy and the 8-hydroxy metabolites are residues of toxicologlcal concern and are to be Included with
bentazon In the tolerances on crops.
7/ The metabolism in animals is not understood as the acid hydrolysis procedure was not run on any of the methanol
extracts of eggs and poultry tissues. This is a data gap and must be corrected.
8/ Tolerance for residues In animal products must be expressed In terms of combined residues of AIBA plus bentazon.
There are no residues of the 6- and 8-hydroxy metabolites in animals which would require representation In the
tolerances for animal products.
9/ In light of the need for additional metabolism data noted above, it is possible that additional residue studies for
new metabolites of concern will be required. If needed, these studies should reflect representative growing regions,
the maximum registered use, sample chromatographs, and methodology which determines the terminal residue of concern.
If the residue samples are stored for a long period of time, storage stability studies for parent and metabolites of
concern will be needed. If detectable residues of bentazon or metabolites of toxicologlcal concern occur in grain,
a milling study will be needed to show the distribution of these residues in the milled fractions. These are
potential data gaps.
43
-------
TABIE A
12 GENERIC DATA REQUIREMENTS FOR BEMTAZON/SODIUM BENTAZON
§158.125 Residue Chemistry, cent.
10/ The recoveries of bentazon from milk at fortifications of 0.05 and 0.1 ppm are not acceptable and must be Improved.
ll/ Data on residues In cannery waste are required.
12/ Testing Is required In Idaho and Washington.
137 Testing Is required In Tennessee and Missouri.
IV Methods and quantitative analyses will be needed If residues of toxlcologlcal concern are Identified from requested
metabolism studies.
18/ Sodium bentazon Is not labeled for use In food/feed handling establishments or other Indoor sites where food/feed
could be contaminated.
19/ Reduction of residue data are required whert the assumption of tolerance level residues would result In predicted
exposure at an unsafe level. Data on the level of residue In food as consumed will be used to obtain a more precise
estimate of potential dietary exposure. The Agency recommends that such data be generated to support all pesticides
requiring a tolerance In case new data are revealed which Indicate that the pesticide Is more toxic than Initially
determined — 10 CPR §158.125(b)(ll).
20/ Includes filing fee.
21/ Changes may be required, depending on the outcome of requested studies.
22/ The Agency will request analytical reference standards If/when needed.
44
-------
13
TABLE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
I/
Data Requirement Composition
§158.130 Environmental Fate
DEGRADATION STUDIES-LAB:
161-1 - Hydrolysis TGAI or PAIRA
Photodegradatlon
161-2 - In water TGAI or PAIRA
161-3 - On soil TGAI or PAIRA
161-4 - In Air TGAI or PAIRA
METABOLISM STUDIES-LAB:
162-1 - Aerobic Soil TGAI or PAIRA •
162-2 - Anaerobic Soil TGAI or PAIRA
162-3 - Anaerobic Aquatic TGAI or PAIRA
162-4 - Aerobic Aquatic TGAI or PAIRA
MOBILITY STUDIES:.
163-1 - Leaching and TGAI or PAIRA
Adsorption/Desorption
163-2 - Volatility (Lab) TEP
163-3 - Volatility (Field) TEP
Use 2/
Pattern
ABC
ABC
: A
N/A
AB
A
C
C
ABC
N/A
N/A
Does EPA Have Must Additional Data
Data To Satisfy Be Submitted Under
This Require- Bibliographic FIFRA § 3(c)(2)(B)?
ment? (Yes, No Citation Time Frame for Data
or Partially) Submission 3/
no yes
no yes
no yes
noV
partial 00040204, 00040208 yes5
00051659
yes 00040204, 00040208 no
no yes
no yes
partial 0004 1081 yes6/
noV
noV
9 months
9 months
9 months
27 months
27 months
27 months
12 months
45
-------
11
TABIE A
.GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
Data Requirement
§158.130 Envirormental Pate -
DISSIPATION STUDIES— FIELD:
161-1 - Soil
161-2 - Aquatic (Sediment)
161-3 - Forestry
161-1 - Combination an!
I/
Composition
Continued
TEP
TEP
TEP
Use 2/
Pattern""
AB
C
N/A
N/A
Does EPA Have
Data To Satisfy
This Require- Bibliographic
ment? (Yes, No Citation
or Partially)
no
no
Must Additional Data
Be Submitted Under
FIFRA § 3(c)(2)(B)?
Time Frame for Data
Submission 3/
yes7V 27 months
yes 27 months
no8/
Tank Mixes
161-5 - Son, Long-term
ACCUMULATION STUDIES;
165-1 - Rotational Crops
(Confined)
165-2 - Rotational Crops
(Field)
TEP
PAIRA
TEP
165-3 - Irrigated Crops TEP
165-1 - In Fish TGAI or PAIRA
165-5 - In Aquatic Non-Target TEP
Organisms
A
A
C
ABC
N/A
no
no
no
partial
00108300"
12/
no9/
yes10/ 30 months
yes10/ 39 months
yes11/ 30 months
yes12/ 12 months
V Composition: TGAI * Technical grade of the active Ingredient; PAIRA » Pure active ingredient, radiolabelled;
TEP » Typical end-use product.
2/ The use patterns are coded as follows: A«Terrestrlal , Food Crop; B"Terrestrlal , Non-Food; C«Aquatic, Food Crop;
D=Aquatlc, Non-Food; E=Greenhouse, Food Crop; F=Qreenhouse, Non-Food; G=Forestry; H=Dcmestic Outdoor; I=Indoor.
-------
TABIE A
15 ' GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BEMTAZON
§158.130 Envirormental Pate, cont.
3/ Data must be submitted witK^the. iodtoatad time frame, based on the date of the Guidance Document.
~ ° 9 Month Due Date Is
0 12 Month Due Date Is
0 27 Month Due Date Is
0 30 Month Due Date Is
0 39 Month Due Date Is Q'f QFC 19B£
V Data are not required due to the relatively low vapor pressure of bentazon.
5_/ Additional work should be done to chemically Identify, If feasible, other soil metabolites that may have formed.
6/ Data on leaching of unaged bentazon In sandy clay loam and loamy sand soils are acceptable. The following
additional data are required: (1) leaching studies on parent conpound and degradation products for two nore
soil types; (2) data on the leaching of degradation products for the two soil types already accepted for
column leaching; and (3) adsorptlon/desorption studies on sediment.
7/ The following studies would be acceptable If data are submitted to Indicate that the test material used was a
typical end-use product: MRID 00108287, 00108288, 00011105, 00011100, 00011390, 00106226, 00011101, 00011101,
00011102, 00108296.
8/ Data requirements for combination products and tank mixes are not addressed In this standard.
£/ Data are not required since results of valid aerobic soil metabolism and terrestrial field dissipation studies
indicate that 50% of residues dissipate prior to recommended subsequent application.
10/ For crops rotated on treated areas, any one of the following will apply:
(a) A tolerance must be obtained for the rotated crop.
(b) The product label must Include a restriction against the rotation of crops used for food or feed
which are not registered for use with sodium bentazon.
(c) Data must be provided to determine time Intervals at which rotated crops planted on treated areas
will be free of pesticide residues.
47
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TABLE A
16 GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
§158.130 Environmental Rite, cont.
ll/ For sodium bentazon use on rice, any one of the following will apply:
(a) A tolerance must be obtained for any crop used for food or feed that Is exposed to Irrigation
water containing bentazon or sodium bentazon residues.
(b) The product label must Include a restriction against the use of Irrigation water containing
bentazon or sodium bentazon residues on crops/grown for food or feed.
(c) Data must be provided to demonstrate conditions under which rice Irrigation water can be used on other
crops without resulting In Illegal plant residues.
12/ Data on residue accumulation In fish are required; a study on catfish Is preferred. The chemical name and structure
of the bentazon residue "NISAA" mentioned In the crawfish uptake study (MRID 00108300) Is needed.
48
-------
17
TABIE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
I/
Data Requiranent Composition
§158.135 Toxicology
ACUTE TESTING:
81-1 - Acute Oral Toxlcity - Rat
81-2 - Acute Dermal Toxlcity
- Rabbit
81-3 - Acute Inhalation Toxlcity
- Rat
81-7 - Delayed
Neurotoxicity - Hen
SUBCHRONIC TESTING:
82-1 - 90-Day Feeding :
- Rodent, and
- Non-rodent (Dog)
82-2 - 21-Day Dermal - Rabbit
82-3 - 90-Day Dermal - Rabbit
82-1 - 90-Day Inhalation:
- Rat
82-5 - 90-Day Neurotoxicity:
- Hen
-Mammal
TGAI
TGAI
TGAI
TGAI
TGAI '
TGAI
TGAI
TGAI
TGAI
Does EPA Have
Data To Satisfy
Use 2/ This Require- Bibliographic
Pattern ment? (Yes, No Citation
or Partially)
A,B,C yes 00064314
A,B,C yes 00041088
A,B,C no
N/A*1 no
A,B,C no
A,B,C no
A,B,C no
N/A5
N/A5
N/A6
N/A6
Must Additional Data
Be Submitted Under
FIFRA § 3(c)(2)(B)?
Time Frame for Data
Submission 3/
no
no
yes
no
yes
yes
yes
no
no
no
no
9 months
15 months
18 months
12 months
-------
18
TABIE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
Data Requirement Composition
§158.1j
CHROI
83-1
83-2
83-3
83-1
55 Toxicology - Continued
4IC TESTING:
- Chronic Toxicity - TGAI
2 species:
- Rodent, and
- Non-rodent (Dog)
- Oncogenlcity - TGAI
2 species:
- Rat (preferred), and
- Mouse (preferred)
- Teratogenlclty - TGAI
2 species:
- Rat
- Rabbit
- Reproduction - Rat TGAI
2-gfcneratlon
Does EPA Have Must Additional Data
Data To Satisfy Be Submitted Under
I/ Use 2/ This Require- Bibliographic PIPRA § 3(c)(2)(B)7
~ Pattern"" ment? (Yes, No Citation Time Frame for Data
or Partially) Submission 3/_
A,B,C no
A,B,C no
A{B,C no
A,B,C no
' A,B,C no
A,B,C no
A,B,C no
yes
11
yes
yes
yes
yes
yes
yes
50 months
50 months
50 months
50 months
15 months
15 months
39 months
MUTAGENICITY TESTING
81-2
81-2
81-2
- Gene Mutation (Ames Test) TGAI
- Structural Chromosomal TGAI
Aberration
- Other Genotoxlc Effects TGAI
A,B,C no
A,B,C no
A,B,C no
yes
yes
yes
9 months
12 months
12 months
SPECIAL TESTING
85-1 - General Metabolism
PAI or PAIRA A,B,C
no
yes
i/
9/
21 months
-------
19
TABLE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
Data Requirement
I/
Composition
Use 2/
Pattern
Does EPA Have
Data To Satisfy
This Require-
ment? (Yes, No
or Partially)
Bibliographic
Citation
Must Additional Data
Be Submitted Under
PIPRA § 3(c)(2)(B)?
Time Frame for Data
Submission 3/
§158.135 Toxicology - Continued
86-1 - Domestic Animal
Safety
Choice
N/A"
10/
no
V Composition: TOAI « Technical grade of the active Ingredient; PAI « Pure active Ingredient; PAIRA • Pure active
Ingredient, radlolabelled; Choice » Choice of several test substances determined on a case-by-case basis.
2/ The use patterns are coded as follows: A«Terrestrlal, Food Crop; B=Terrestrlal, Non-Food; C«Aqautic, Food Crop;
D=Aquatlc, Non-Food; EKJreenhouse, Food Crop; F=Greenhouse, Non-Food; G«Forestry; H=Donestic Outdoor; I=Indoor.
3/ Data must be submitted within ^he, ^^flffld time frame, based on the date of the Guidance Document.
0 9 Month Due Date is
0 12 Month Due Date is
0 15 Month Due Date is
0 18 Month Due Date is
0 21 Month Due Date is
0 39 Month Due Date is
0 50 Month Due Date is
V Bentazon is neither an organophosphate, nor an analog of a neurotoxic compound, hence no delayed neurotoxicity study
Is required.
5_/ This study is not applicable to exposure conditions.
6/ This study is not applicable to exposure conditions. See footnote #1 above.
77 A one-year dog study is required.
8/ Metabolism testing using sodium bentazon Is also required to determine whether there is any difference from bentazon.
£/ Although the Agency does not have a chronic data base, there is indication of possible teratogenicity, for example.
It Is Important to examine dermal absorption at this time to better understand potential exposure. This will enable
the Agency to determine whether adequate margins of safety exist, should'adverse effects be seen In required studies.
10/ There Is no evidence of high acute or subacute toxlcity.
51
-------
20
TABLE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
Must Additional Data
Be Submitted Under
PIPRA § 3(c)(2)(B)7
Time Frame for Data
Submission 3/
Data Requirement
V Use 2/
Composition" Pattern
Does EPA Have
Data Tfo Satisfy
Dils Require-
ment? (Yes, No
or Partially)
Bibliographic
Citation
§158.110
132-1
132-1
133-3
133-1
§158.112
201-1
201-1
Reentry Protection
- Foliar Dissipation
- Soil Dissipation
- Dermal Exposure
- Inhalation Exposure
Spray Drift
- Droplet Size Spectrum
- Drift Field Evaluation
TEP
TEP
TEP
TEP
TEP
TEP
N/A
N/A
N/A
N/A
N/A
N/A-
no
no
no
no
no
no
\l Composition: TEP - Typical end-use product.
2/ The use patterns are coded as follows: A-Terrestrlal, Food Crop; B-Terrestrial, Non-Food; C«Aquatic, Food Crop;
D=Aquatlc, Non-Food; E=Greenhouse, Food Crop; F=Qreenhouse, Non-Food; G=Forestry; H8Dcmestlc Outdoor; I=Indoor.
52
-------
21
TABLE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
i/
Data Requirement Composition
Use 2_/
Pattern
Does EPA Have
Data To Satisfy
This Require- Bibliographic
ment? (Yes, No Citation
or Partially)
Must Additional Data
Be Submitted Under
FIFRA § 3(c)(2)(B)7
Time Frame for Data
Submission 3/
§158.145 Wildlife and
Aquatic Organisms
AVIAN AND MAMMALIAN TESTING
71-1
71-2
71-3
71-4
71-5
- Acute Avian Oral Toxicity TGAI
- Avian Subacute Dietary TGAI
Toxicity
- Upland Game Bird, and
- Waterfowl
- Wild Maranal Toxicity TGAI
- Avian Reproduction TGAI
- Upland Game Bird, and
- Waterfowl
- Staulated or Actual
Field Testing TEP
- Mammals, and
- Birds
A,B,C
A,B,C
: A,B,C
A,B,C
A,B,C
A,B,C
A,B,C
partially 00041804, 00041077
partially 00108851
partially 00108850
no
partially 00083345
partially 00124702
no
no
yes 9 months
v
yes 9 months
I/
yes 9 months
no
4,6/
yes 9 months
4t6/
yes 9 months
no
no
AQUATIC ORGANISM TESTING
72-1
- Freshwater Fish Toxicity
- Coldwater Fish Species TGAI
TEP
A,B,C
C
partially 00041075
partially . 00041076
53
I/
yes 9 months
I/
yes 9 months
-------
22
TABLE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
I/ Use 2/
Data Requirement Composition"" Pattern""
Does EPA Have
Data To Satisfy
This Require- Bibliographic
merit? (Yes, No Citation
or Partially)
Must Additional bata
Be Submitted Under
FIFRA § 3(c)(2)(B)?
Time Frame for Data
Submission 3/
§158.145 Wildlife and
Aquatic Organisms - Continued
72-2
72-3
and
- Warmwater Fish Species
- Acute Toxlclty to
Freshwater Invertebrates
- Acute Toxlclty to
TOAI
TEP
TOAI
TEP
TOAI
A,B,C
C
A,B,C
C
partially 00041075
partially 00041076
partially 00106240
no
I/
yes
yes""
v
yes
yes
9 months
9 months
9 months
9 months
Estuarlne and Marine Organisms
72-4
72-5
72-6
- Flah
- Mollusk
- Shrimp
- Flah Early Life Stage,
and
- Aquatic Invertebrate
Life-Cycle
- Fish - Life-Cycle
- Aquatic Organism TGAI
TOAI
TOAI
TCAI
, PAI or
A,B,C
A,B,C
A,B,C
A,B,C
A,B,C
t
A,B,C
Degradation
no
no
no
no
no
no
no
I!
yes
no
12 months
6/
reserved"
6/
reserved"
6/
reserved"
Accumulation Product
- Crustacean
- Fish
- Insect Nymph
- Mollusk
A,B,C
A,B,C
A.B.C
no
no
no
no ^A
no
y
yes
no
no
-------
23
TABIE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM EENTAZON
Data Requirement
I/ Use 21
Composition Pattern
Does EPA Have
Data To Satisfy
This Require-
ment? (Yes, No
or Partially)
Bibliographic
Citation
Mist Additional Data
Be Submitted Under
FIFRA § 3(c)(2)(B)?
Time Frame for Data
Submission I/
§158.115 Wildlife and Aquatic Organisms - Continued
72-7 - Simulated Field Testing TEP
- Aquatic Organisms A,B,C no
- Actual Field Testing TEP
-Aquatic Organisms A,B,C no
y
reserved
6/
reserved
_!/ Composition: TQAI » Technical grade of the;active Ingredient; PAI « pure active Ingredient;
TEP » Typical end-use product;
2J The use patterns are coded as follows: A=Terrestrial, Food Crop; B^Terrestrlal, Non-Food Crop; C^Aquatlc, Food Crop;
D=Aquatic, Non-Food; E=Greenhouse, Food Crop; F=Greenhouse, Non-Food; G=Forestry; H=Donestlc Outdoor; I=Indoor.
3/ Data must be submitted within the indie
~ ° 9 Month Due Date Is 0.7 j''"
0 12 Month Due Date is 97 Q
Li time frame, based on the date of the Guidance Document.
V The composition of the test material, including percent active ingredient, must be clarified/verified.
5_/ An oyster study is required regarding the rice use (aquatic) and the turf, corn, and soybean uses (since there are
greater than 300,000 acres of each of these in coastal counties). This study is also needed to evaluate the
potential for hazard to endangered mussel species. Fish and shrimp studies are not required at this time due to the
low toxlcity seen In other aquatic studies.
6/ Tnis study is not required for hazard assessment at the present time. Following Agency review of product and
environmental chemistry data requested In this Registration Standard, reevaluation of ecological effects data
requirements will be made.
77 See requirement in table under §158.130.
-------
TABIE A
GENERIC DATA REQUIREMENTS FOR BENTAZCN/SODIUM BBNTAZON
Must Additional Data
Be Submitted Under
PIPRA § 3(c)(2)(B)7
Time Frame for Data
Submission 3/
Data Requirement
I/ Use 2/
Composition Pattern
Does EPA Have
Data To Satisfy
This Require-
ment? (Yes, No
or Partially)
Bibliographic
Citation
J158.150 Plant Protection
121-1 - TARGET AREA
EF
PHYTOTQXICITY
NONTARGET AREA PHYTOTOXICITY TIER I
122-1 - Seed Germination/ TOAI
Seedling Emergence
122-1 - Vegetative Vigor TOAI
122-2 - Aquatic Plant Growth TGAI
TIER II
123-1 - Seed Germination/ TOAI
Seedling Emergence
123-1 - Vegetative Vigor TCAI
123-2 - Aquatic Plant Growth TGAI
TIER III
121-1 - Terrestrial Field TEP
121-2 - Aquatic Field TEP
A
A
I/
I/
I/
I/
I/
I/
I/ Composition: TGAI » Technical grade of the active ingredient; TEP - Typical end-use product. EP » End-use product.
2_/ The use patterns are coded as follows: A*Terrestrial, Food Crop; B=Terrestrlal," Non-Food Crop; C=Aquatlc, Food Crop;
D^Aquatlc, Non-Food; EsGreenhouse, Food Crop; F=Greenhouse, Non-Food; G=Forestry; H=Dcmestic Outdoor; I=Indoor.
3/ These data are not required at this time, In accordance with §158.150.
-------
25
TABIE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
Data Requirement
I/ Use 21
Composition Pattern
Does EPA Have
Data To Satisfy
This Require-
ment? (Yes, No
or Partially)
Bibliographic
Citation
Must Additional Data
Be Submitted Under
PIPRA § 3(c)(2)(B)?
Time Frame for Data
Submission 3/
§158.155 Nontarget Insect
NONTAROET INSECT TESTING -
POLLINATORS;
141-1 - Honey bee acute
contact toxlclty TGAI
141-2 - Honey bee - toxlclty TEP
of residues on
foliage
- Honey bee subacute (Reserved)
feeding study
111-5 - Field testing for TEP
pollinators
NONTAROET INSECT TESTING -
AQUATIC INSECTS;
142-1 - Acute toxlclty to (Reserved)
aquatic Insects
142-1 - Aquatic Insect (Reserved)
liio-cycle study
142-3 - Simulated or actual (Reserved)
field testing for
aquatic Insects
143-1 - NONTARGET INSECT (Reserved)
TESTING - PREDATORS
thru AND PARASITES
143-3
A,B,C
.A,B,C
no
no
yes
no
9 months
57
-------
26 TABLE A
GENERIC DATA REQUIREMENTS FOR BENTAZON/SODIUM BENTAZON
§158.155 Nontarget Insect - Continued
I/ Composition: TGAI » Technical grade of the active ingredient; TEP » Typical end-use product.
2/ The use patterns are coded as follows: A-Terrestrlal, Pood Crop; B-Terrestrlal, Non-Pood; C«Aquatic, Pood Crop:
D-Aqautlc, Non-Pood; E'Greenhouse, Pood Crop; F«Greenhouse, Non-Pood; G»Porestry; H=Dcmestlc Outdoor; I«Indoor.
3/ Data must be submitted within the indicated, time frame, based on the date of the Guidance Document.
0 9 Month Due Date is 97 .1UN \\
58
-------
III. REQUIREMENT FOR SUBMISSION OF PRODUCT-SPECIFIC DATA
Note: Unless stated otherwise in Section I, Regulatory
Position and Rationale, this Section applies only to manufac-
turing use products, not to end use products.
A necessary first step in determining which statements
must appear on your product's label is the completion and
submission to EPA of product-specific data* listed on the
form entitled "Product Specific Data Report" (EPA Form
8580-4, Appendix III-l) to fill gaps identified by EPA
concerning your product. Under the authority of PIPRA sec.
3(c)(2)(B), EPA has determined that you must submit these
data to EPA in order to reregister your product(s). All of
these data must be submitted not later than six months after
you receive this guidance document.
Table B—Product-Specific Data Requirements for Manufacturing
Use Products—lists the product specific data you must submit.
Data that are required to be submitted are identified in the
column of those tables entitled "Must Data By Submitted
Under §3(c)(2)(B)."
J|/ Product specific data pertain to data that support the
formulation which is marketed; it usually includes product
chemistry data and acute toxlcity data.
59
-------
27
TABLE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURIN3-USE PRODUCTS CONTAINING SODIUM BENTAZON
Guideline Citation and Test
Name of Test Substance
§158.120 Product Chemistry
Product Identity:
61-1 - Product Identity and Disclosure
of Ingredients
61-2 - Description of Beginning Materials
and Manufacturing Process
61-3 - Discussion of Formation of
Impurities
Analysis and Certification of Product
Ingredients
62-1 - Preliminary Analysis
62-2 - Certification of Limits
62-3 - Analytical Methods to Verify
Certified Limit
Physical and Chemical Characteristics
63-2 - Color
63-3 - Physical 'State
63-4 - Odor
MP
MP
MP :
MP
MP
MP
MP
MP
MP
Guidelines
Status
R
R
R
CR
R
R
R
R
R
Are Data
Required
Yes No
on n
[ft n
[ft n
[ft n
[ft n
ra O
n m
n on
n ra
Data Must Be
Footnote Submitted Within
Number Time Frames Listed
Below IL
2 6 months
3 6 months
3 6 months
3 . 12 months
3 12 months
3 12 Months
60
-------
28
TABIE B
PRODUCT SPECIFIC DATA. REQUIREMENTS FOR MANUFACTURIM3-USE PRODUCTS CONTAINING SODIUM BENTAZON
Guideline Citation and Test Guidelines
Name of Test Substance Status
t
§158.120 Product Chemistry (Continued)
Physical and Chemical Characteristics (Cont,
63-7 - Density, Bulk Density, or
Specific Gravity
63-12 - pH
63-11 - Oxidizing or Reducing Action
63-15 - Flanmablllty
63-16 - Explodabillty
63-17 - Storage Stability
63-18 - Viscosity
63-19 - Mlscibility
63-20 - Corrosion Characteristics
Other Requirements:
I/
61- 1 - Submit tal of samples
MP » Manufacturing-use Product; R « Reqult
I/ Data must be submitted withinrithei JUKI if
0 6 Month Due Date is * ' MAK 1
0 12 Month Due Date is 0 +> ^ £ -» 1C
0 15 Month Due Date is O 7 Hf1 M(
/
MP R
MP CR
MP CR
MP CR
MP R
MP R
MP CR
MP CR
MP R
MP CR
•ed; CR » Conditionally
«fced time frame, based
J-K
UR
Data Must Be
Are Data Footnote Submitted Within
Required Number Time Frames Listed
Yes No Below If
[X] [ ] 3 6 months
[!Q Hi 3 6 months
[ITl [~) 3 6 months
n m
[7] ["] 3 6 months
n m
n m
n m
[IT] [~] 3 15 months
n n
Required
on the date of the Guidance Document.
2_/ An updated statement of composition is needed from BASF Wyandotte Corporation.
3_/ Update as per current Product Chemistry guidelines (Subdivision D).
I/ The Agency will request samples if/when needed. If requested/ the time permitted for submittal will be 6 months.
~ O I
-------
29
TABIE B
PRODUCT SPECIFIC DATA REQUIREMENTS FOR MANUFACTURINQ-USE PRODUCTS CONTAINING SODIUM BENTAZON
Must Additional Uata
Be Submitted Under
PIFRA § 3(c)(2)(B)?
Time Frame for Data
Submission?/
Data Requirement
Composition"
I/
Does EPA Have
Data To Satisfy
This Require-
ment? (Yes, No
or Partially)
Bibliographic
Citation
§158.135 Toxicology
ACUTE TESTING
81-1 - Acute Oral Toxlclty - Rat MP
81-2 - Acute Dermal Toxlclty MP
- Rabbit
81-3 - Acute Inhalation Toxlclty MP
- Rat
81-4 - Primary Eye MP
Irritation - Rabbit
81-5 - Primary Dermal MP
Irritation - Rabbit
81-6 - Dermal Sensltizatlon - MP
Guinea Pig
yes
yes
no
I/
I/
no
00064314
00041088
• •••••••••••••••••••••••••••••••••••••••••
••••••••I
no
no
yes
I/
I/
yes
I/ Composition: MP » Manufacturing-use product.
2/ Data must be submitted within the indicated time frame, based on the date of the Guidance Document,
0 9 Month Due Date Is
* * l/l f*r .U IflUk A\* U l/\*Vt t,
27 JUN1986
3/ No additional data is required at this time using MP. Available studies in these categories
have not been re-reviewed for this Registration Standard.
9 months
9 months
62
-------
IV. SUBMISSION OF REVISED LABELING
Note; This section applies to all products.
PIPRA requires each product to be labeled with accurate,
complete and sufficient instructions and precautions, reflecting
the results of data concerning the product and its ingredients.
Labeling requirements are set out in 40 CPR 162.10 (see
Appendix IV-1) and are summarized for products containing
this active ingredient as part of this Guidance Document
(See Appendix IV-2). Applications submitted in response to
this notice must Include draft labeling for Agency review.
If you fall to submit revised labeling information
complying with this section (supplemented by requirements
described in Section I, Regulatory Position and Rationale),
EPA may issue a notice of intent to cancel the registration
under PIPRA sec. 6(b)(l).
A. Label Contents
40 CPR 162.10 requires that certain specific labeling
statements appear at certain locations on the label. This
is referred to as format labeling. Specific label items
listed below are keyed to Appendix IV-2.
Item 1. PRODUCT NAME - The name, brand or trademark is
required to be located on the front panel, preferably centered
In the upper part of the panel. The name of a product will
not be accepted if It is false or misleading.
Item 2. COMPANY NAME AND ADDRESS - The name and address
of the registrant or distributor is required on the label.
The name and address should preferably be located at the
bottom of the front panel or at the end of the label text.
' ^«
Item 3. NET CONTENTS - A net contents statement is
required on all labels or on the container of the pesticide.
The preferred location is the bottom of the front panel
immediately above the company name and address, or at the end
of the label text. The net contents must be expressed in the
largest suitable unit, e.g., "1 pound 10 ounces" rather than
"26 ounces." In addition to English units, net contents may
be expressed in metric units. See Appendix IV-1. [40 CFR
I62.10(d)]
63
-------
Item 4. EPA REGISTRATION NUMBER - The registration
number assigned to the pesticide product must appear on the
label, preceded by the phrase "EPA Registration No.," or "EPA
Reg. No." The registration number must be set in type of a
size and style similar to other print on that part of the
label on which it appears and must run parallel to it. The
registration number and the required identifying phrase must
not appear in such a manner as to suggest or imply recommendation
or endorsement of the product by the Agency. See Appendix IV-1.
[40 CPR I62.10(e)3
Item 5. EPA ESTABLISHMENT NUMBER - The EPA establishment
number, preceded by the phrase "EPA Est." is the final estab-
lishment at which the product was produced, and may appear
In any suitable location on the label or immediate container.
It must also appear on the wrapper or outside container of
the package if the EPA establishment number on the immediate
container cannot be clearly read through such wrapper or container.
See Appendix IV-1. [40 CPR I62.10(f)]
Item 6A. INGREDIENTS STATEMENT - An ingredients statement
is required on the front panel. The ingredients statement must
contain the name and percentage by weight of each active ingredient
and the total percentage by weight of all inert ingredients.
The preferred location is immediately below the product name.
The ingredients statement must run parallel with, and be clearly
distinguished from, other text on the panel. It must not be
placed in the body of other text. See Appendix IV-1. [40 CPR
162.10(g)]
Item 6B. POUNDS PER GALLON STATEMENT - For liquid agricul-
tural formulations, the pounds per gallon of active ingredient
must be Indicated on the label.
Item 7. FRONT LABEL PRECAUTIONARY STATEMENTS - Front panel
precautionary statements mus't be grouped together, preferably
within a block outline. The table below shows the minimum type
size requirements for various size labels.
Size of Label Signal Word "Keep Out of Reach
on Front Panel Minimum Type Size of Children"
in Square Inches All Capitals Minimum Type Size
5 and under 6 point 6 point
above 5 to 10 10 point 6 point
above 10 to 15 12 point 8 point
above 15 to 30 14 point 10 point
over 30 18 point 12 point
Item 7A. CHILD HAZARD WARNING STATEMENT - The statement
"Keep Out of Reach of Children" must be located on the front
panel above the signal word except where contact with children
during distribution or use is unlikely. See Appendix IV-1.
[40 CFR I62.10(h)(l)(ii)]
64
-------
Item 7B. SIGNAL WORD - The signal word (DANGER, WARNING,
or CAUTION) is required on the front panel immediately below
the child hazard warning statement. See Appendix IV-1 .
[40 CPR 162.10 (h)(l)(i)]
Item 7C. SKULL & CROSSBONES AND WORD "POISON" - On products
assigned a toxicity Category I on the basis of oral, dermal,
or inhalation toxicity, the -word "Poison" shall appear on the
label in red on a background of distinctly contrasting color and
the skull and crossbones shall appear in immediate proximity to
the word POISON. See Appendix IV-1. [40 CPR 162.10(h) (1) (i)]
Item 7D. STATEMENT OP PRACTICAL TREATMENT - A statement
of practical treatment (first aid or other) shall appear on
the label of pesticide products in toxicity Categories I,
II, and III. See Appendix IV-1. [40 CPR I62.10(h)(l)(iii)]
Item 7E. REFERRAL STATEMENT - The statement "See Side
(or Back) Panel for Additional Precautionary Statements" is
required on the front panel for all products, unless all
required precautionary statements appear on the front panel.
See Appendix IV-1. [40 CPR I62.10(h) (1) (ill)]
Item 8. SIDE/BACK PANEL PRECAUTIONARY LABELING - The
precautionary statements listed below must appear together
on the label under the heading "PRECAUTIONARY STATEMENTS."
The preferred location is at the top of the side or back
panel preceding the directions for use, and it is preferred
that these statements be surrounded by a block outline. Each
of the three hazard warning statements must be headed by the
appropriate hazard title. See Appendix IV-1. [40 CPR 162.10
Item 8A. HAZARD TO HUMANS AND DOMESTIC ANIMALS - Where a
hazard exists to humans or domestic animals, precautionary
statements are required indicating the particular hazard, the
route(s) of exposure and the precautions to be taken to avoid
accident, injury or damage. See Appendix IV-1. [40 CPR 162.10
Item 8B. ENVIRONMENTAL HAZARD - Where a hazard exists to
non- target organisms excluding humans and domestic animals,
precautionary statements are required stating the nature of
the hazard and the appropriate precautions to avoid potential
accident, injury, or damage. See Appendix IV-1. [40 CFR
65
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Item 8C. PHYSICAL OR CHEMICAL HAZARD
1. Flammability statement. Precautionary statements relating
to flammability of a product are required to appear on the
label if it meets the criteria in Appendix IV-3. The require-
ment is based on the results of the flashpoint determinations
and flame extension tests required to be submitted for all
products. These statements are to be located in the side/back
panel precautionary statements section, preceded by the
heading "Physical/Chemical Hazards." Note that no signal
word is used in conjunction with the flammability statements.
2. Criteria for declaration of non-flammability.' The
following criteria will be used to determine if a product
is non-flammable:
a. A "non-flammable gas" is a gas (or mixture of gases)
that will not ignite when a lighted match is placed
against the open cylinder valve.
b. A "non-flammable liquid" is one having a flashpoint
greater than 350°P (177°C).
c. A "non-flammable aerosol" is one which meets the
following criteria:
1. The flame extension is zero inches;
11. There is no flashback; and
ill. The flashpoint of the non-volatile liquid
component is greater than 350°F (177°C).
3. Declaration of non-flammability. Products which
meet the criteria for non-flammability specified above
may bear the notation ,"n.on-flammable" or "non-flammable
(gas, liquid, etc.)" on the label. It may appear as a
substatement to the Ingredients statement, or on a back
or side panel, but shall not be highlighted or emphasized
(as with an inordinately large type size) In any way
that may detract from precaution.
1. Other physical/chemical hazard statements. When
chemistry data demonstrate hazards of a physical or
chemical nature other than flammability, appropriate
statements of hazard will be prescribed. Such statements
may address hazards of exploslvity, oxidizing or reducing
capability, or mixing with other substances to produce
toxic fumes.
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Item 9A. RESTRICTED USE CLASSIFICATION - PIPRA sec. 3(d)
requires that all pesticide formulations/uses be classified
for either general or restricted use. Products classified
for restricted use may be limited to use by certified applicators
or persons under their direct supervision (or may be subject
to other restrictions that may be Imposed by regulation).
In the Registration Standard, the Agency has (1) indicated
certain formulations/uses are to be restricted (Section I
Indicates why the product has been classified for restricted
use); or (2) reserved any classification decision until
appropriate data are submitted.
The Regulatory Position and Rationale states whether
products containing this active ingredient are classified
for restricted use. If they are restricted the draft label(s)
submitted to the Agency as part of your application must
reflect this determination (see below).
If you do not believe that your product should be classified
for restricted use, you must submit any Information and
rationale with your application for reregistration. During
the Agency's review of your application, your proposed classi-
fication determination will be evaluated in accordance with
the provisions of 1»0 CPR I62.11(c). You will be notified of
the Agency's classification decision.
Classification Labeling Requirements
If your product has been classified for restricted use,
the following label requirements apply:
1. Front panel statement of restricted use classification.
a. The statement "Restricted Use Pesticide" must
appear at the top ,of the front panel of the label.
The statement must be set In type of the same
minimum size as required for human hazard signal
word (see table in HO CFR l62.10(h)(l)(iv)
b. Directly below this statement on the front panel,
a summary statement of the terms of restriction must
appear (including the reasons for restriction If
specified in Section I). If use is restricted to
certified applicators, the following statement is
required: "For retail sale to and use only by
Certified Applicators or persons under their direct
supervision and only for those uses covered by the
Certified Applicator's Certification.1'
2. Some but not all uses restricted. If the Regulatory
Position and Rationale states that some uses are classified
for restricted use, and some are unclassified, several courses
of action are available:
67
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a. You may label the product for Restricted use.
If you do so, you may Include on the label uses that
are unrestricted, but you may not distinguish them
on the label as being unrestricted.
b. You may delete all restricted uses from your
label and submit draft labeling bearing only unrestricted
uses.
c. You may "split" your registration, i.e., register
two separate products with Identical formulations, one
bearing only unrestricted uses, and the other bearing
restricted uses. To do so, submit 'two applications for
reregistration, each containing all forms and necessary
labels. Both applications should be submitted simul-
taneously. Note that the products will be assigned
separate registration numbers.
Item 9B [There is no Item 9B].
Item 9C. MISUSE STATEMENT - All products must bear the
misuse statement, "It Is a violation of Federal law to use
this product in a manner Inconsistent with its labeling."
This statement appears at the beginning of the directions
for use, directly beneath the heading of that section.
Item 10A. REENTRY STATEMENT - If a reentry Interval
has been established by the Agency, it must be included on
the label. Additional worker protection statements may be
required in accordance with PR Notice 83-2, March 29, 1983.
Item 10B [There is no Item 10B].
Item IOC. STORAGE AND DISPOSAL BLOCK - All labels are
required to bear storage ahcT disposal statements. These
statements are developed for specific containers, sizes, and
chemical content. These instructions must be grouped and
appear under the heading "Storage and Disposal" in the directions
for use. This heading must be set in the same type sizes as
required for the child hazard warning. Refer to Appendix
IV-JJ, IV-5, and IV-6 to determine the storage and disposal
Instructions appropriate for your products.
Item 10D. DIRECTIONS FOR USE - Directions for use must
be stated in terms which can be easily read and understood by
the average person likely to use or to supervise the use of
the pesticide. When followed, directions must be adequate to
protect the public from fraud and from personal injury and to
prevent unreasonable adverse effects on the environment. See
Appendix IV-1. [40 CFR 162.10]
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B. Collateral Labeling
bulletins, leaflets, circulars, brochures, data sheets,
flyers, or other written or graphic printed matter which is
referred to on the label or which is to accompany the product
are termed collateral labeling. Such labeling may not bear
claims or representations that differ in substance from those
accepted in connection with registration of the product. It
should be made part of the response to this notice and submitted
for review.
V. INSTRUCTIONS FOR SUBMISSION
A. For Manufacturing Products (MP) containing (name of
pesticide) as sole active ingredient.
1. Within 90 days from receipt of this document, you must
submit to the Product Manager in the Registration Division at
the address given at the end of this section the "FIFRA Section
3(c)(2)(B) Summary Sheet" EPA Form 8580-1. Refer to Appendix
II-3 with appropriate attachments.
If on the Summary Sheet, you commit to develop the data,
request a minor chemical exemption, present arguments that a
data requirement is not applicable, or submit protocols or modified
protocols for Agency review, you must also submit a copy of the
Summary Sheet (and any supporting information) to the Office of
Compliance Monitoring, which will be monitoring the data generated
in response to this notice. This information should be submitted
to the Office of Compliance Monitoring at the address given at
the end of this section. (Actual studies are not to be submitted.)
2. Within 6 months from receipt of this document you must
submit to the Product Manager on the Registration Division:
a. Confidential .Statement of Formula, EPA Form 8570-4.
b. Product Specific Data Report, EPA Form 8580-4
(Appendix III-l).
c. Two copies of any required product-specific data
(See Tables B).
d. Two copies of draft labeling, including the label and
associated brochures. If current labeling conforms to the
requirements of this guidance document and the results of
the short-term data, you may submit such labeling. End use
product labeling must comply specifically with the Instructions
in Section I (Regulatory Position and Rationale) of this
guidance document. The labeling should be either typewritten
69
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text on 8-1/2 x 11 Inch paper or a raockup of the labeling
suitable for storage in 8-1/2 x 11 inch files. The draft
label must indicate the intended colors of the final label,
clear indication of the front panel label, and the intended
type sizes of the text.
e. Evidence of compliance with data support requirements
of PIPRA sec. 3(c)(l)(D). Refer to 40 CPR 152.80-152.99
for latest requirements.
3. Within the times set forth in Table A, you must submit
to the Registration Division all generic data, unless you are
eligible for the formulator's exemption. If for any reason any
test is delayed or aborted so that the agreed schedule cannot be
met, notify the Product Manager and the Office of Compliance
Monitoring.
B. For Manufacturing Use Products containing (name of pesticide)
in combination with other active ingredients
1. Within 90 days from receipt of this document, you must
submit the "PIPRA Section 3(c)(2)(B) Summary Sheet," EPA Form
8580-1. Refer to Appendix II-3 with appropriate attachments.
If on the Summary Sheet, you commit to develop the data,
request a minor chemical exemption, present arguments that a data
requirement is not applicable, or submit protocols or modified
protocols for Agency review, you must also submit a copy of the
Summary Sheet (and any supporting information) to the Office of
Compliance Monitoring, which will be monitoring the data generated
in response to this notice. This information should be submitted
to the Office of Compliance Monitoring at the address given at
the end of this section. (Actual studies are not to be submitted.)
2. Within the times set forth in Table A, you must submit
to the Registration Division all generic data, unless you are
eligible for the formulator's exemption. If for any reason any
test is delayed or aborted so that the agreed schedule cannot be
met, notify the Product Manager and the Office of Compliance
Monitoring.
70
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C. For End Use Products containing (name of pesticide) alone
or in combination with other active ingredients;
1. Within 90 days from receipt of this document, you must
submit the "PIERA Section 3(c)(2)(B) Summary Sheet," EPA Form
8580-1. Refer to Appendix II-3 with appropriate attachments.
If on the Summary Sheet, you commit to develop the data,
request a minor chemical exemption, present arguments that a
data requirement is not applicable, or submit protocols or modified
protocols for Agency review, you must also submit a copy of the
Summary Sheet (and any supporting information) to the Office of
Compliance Monitoring, which will be monitoring the data generated
in response to this notice. This information should be submitted
to the Office of Compliance Monitoring at the address given at
the end of this section. (Actual studies are not to be submitted.)
2. Within 6 months from receipt of this document you must
submit:
a. Confidential Statement of Formula, EPA Form 8570-4.
b. Product-Specific Data Report, EPA Form 8580-4
(Appendix III-l), if applicable (if Table C lists required
product-specific data).
c. Two copies of any required product-specific data,
if applicable (if Table C lists required product-specific
data).
d. Two copies of draft labeling, including the label and
associated brochures. If current labeling conforms to the
requirements of this guidance document and the results of
the short-term data, you may submit such labeling. End use
product labeling must comply specifically with the instructions
in Section I (Regulatory Position and Rationale) of this
guidance document. Labeling should be either typewritten
text on 8 1/2 x 11 inch paper or a mockup of the labeling
suitable for storage In 8 1/2 inch files. The draft label
must Indicate the intended colors of the final label, clear
indication of the front panel label, and the Intended type
sizes of the text.
3. Within the time frames set forth in Table A, submit all
generic data, unless you are eligible for the formulator's
exemption.
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D. For intrastate products containing (name of pesticide)
either as the sole active Ingredient or In combination
with other active Ingredients
These products are being called In for full Federal
registration. Producers of these products are being sent
a letter instructing them how to submit an application for
registration.
E. Addresses
Applications and other required information should be
submitted to the following address:
Robert Taylor, Product Manager (25)
Registration Division (TS-767C)
Office of Pesticide Programs
Environmental Protection Agency
401 M St., SW.
Washington, D.C. 20460
Phone No. (703) 557-1800
The address for submission to the Office of Compliance Monitoring
is:
Laboratory Data Integrity Program
Office of Compliance Monitoring (EN-342)
Environmental Protection Agency
401 M St., SW.
Washington, D.C. 20460
72
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Appendix II-l
Guide to Use of This Bibliography
1. CONTENT OP BIBLIOGRAPHY. This bibliography contains
citations of all studies considered relevant by EPA in
arriving at the positions and conclusions stated elsewhere
in the Standard. Primary sources for studies In this
bibliography have been the body of data submitted to EPA
and Its predecessor agencies In support of past regulatory
decisions. Selections from other sources Including the
published literature, in those Instances where they have
been considered, will be Included.
2. UNITS OP ENTRY. The unit of entry In this bibliography
Is called a "study." In the case of published materials,
this corresponds closely to an article. In the case of
unpublished materials submitted to the Agency, the Agency
has sought to Identify documents at a level parallel to
the published article from within the typically larger
volumes in which they were submitted. The resulting
"studies" generally have a distinct title (or at least a
single subject), can stand alone for purposes of review,
and can be described with a conventional bibliographic
citation. The Agency has attempted also to unite basic
documents and commentaries upon them, treating them as a
single study.
3. IDENTIFICATION OP ENTRIES. The entries in this bibliography
are sorted numerically by "Master Record Identifier," or
MRID, number. This number is unique to the citation, and
should be used at any time specific reference is required.
It Is not related to the six-digit "Accession Number"
which has been used to Identify volumes of submitted
studies; see paragraph 2f(d)(4) below for a further explana-
tion. In a few cases, entries added to the bibliography
late In the review may be preceded by & nine-character
temporary identifier. These entries are listed after
all MRID entries. This temporary identifier number Is
also to be used whenever specific reference is needed.
4. FORM OF ENTRY. In addition to the Master Record Identifier
(MRID), each entry consists of a citation containing
standard elements followed, in the case of material
submitted to EPA, by a description of the earliest known
submission. Bibliographic conventions used reflect the
standards of the American National Standards Institute
(ANSI), expanded to provide for certain special needs.
73
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Appendix II-l (continued)
a. Author. Whenever the Agency could confidently identify
one, the Agency has chosen to show a personal author.
When no individual was identified, the Agency has
shown an identifiable laboratory or testing facility
as author. As a last resort, the Agency has shown
the first submitter as author.
b. Document Date. When the date appears as four digits
with no question marks, the Agency took it directly
from the document. When a four-digit date is followed
by a question mark, the bibliographer deduced the
date from evidence in the document. When the date
appears as (19??)* the Agency was unable to determine
or estimate the date of the document.
c. Title. In some cases, it has been necessary for
Agency bibliographers to create or enhance a document
title. Any such editorial insertions are contained
between square brackets.
d. Trailing Parentheses. For studies submitted to the
Agency in the past, the trailing parentheses include
(In addition to any self-explanatory text) the fol-
lowing elements describing the earliest known submission:
(1) Submission Date. The date of the earliest known
submission appears immediately following the word
"received."
(2) Administrative Number. The next element,
Immediately following the word "under," is the
registration number, experimental use permit
number, petition number, or other administrative
number associated with the earliest known submission
* * *
(3) Submitter. The third element is the submitter,
following the phrase "submitted by." When
authorship is defaulted to the, submitter, this
element Is omitted.
(M) Volume Identification (Accession Numbers). The
final element in the trailing parentheses
identifies the EPA accession number of the volume
in which the original submission of the study
appears. The six-digit accession number follows
the symbol "CDL," standing for "Company Data
Library." This accession number is in turn
followed by an alphabetic suffix which shows the
relative position of the study within the volume.
For example, within accession number 123^56,-the
first study would be 123^56-Aj the second, 123^56-
B; the 26th, 123^56-Z; and the 27th, 123^56-AA.
74
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OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Bentazon/Sodiurn Bentazon Standard
MR ID CITATION
00023507 BASF Wyandotte Corporation (19??) Residues of Bentazon, 6- and 8-
Hydroxy Bentazon in Corn, Soybeans, Peanuts, Dry Beans, Mint,
and Succulent Beans and Peas. (Unpublished study received Jun
5, 1979 under 7969-45; CDL:238951-C)
00023508 BASF Wyandotte Corporation (1978) Residues of Bentazon, 6- and 8-
Hydroxy Bentazon, and Atrazine in Corn Grain. (Unpublished
study received Jun 5, 1979 under 7969-45; CDL:238951-E)
00023509 BASF Wyandotte Corporation (19.74) Determination of Bentazon...8-
Hydroxy-Bentazon...and 6-Hydroxy Bentazon...Residues in Whole
Soybean Plants of Foliage and Soybean Grain. Method no. 11A
dated Jun 25, 1974. (Unpublished study received Jun 5, 1979
under 7969-45; CDL:238951-F)
00023511 BASF Wyandotte Corporation (1977) Determination of Bentazon, 8-
Hydroxy Bentazon, and 6-Hydroxy Bentazon in Corn...Peanuts...and
Mint (Fresh Hay, Spent Hay and Oil). Method no. 21A dated Jan
25, 1977. (Unpublished study received Jun 5, 1979 under 7969-
45; CDL.-238951-H)
00026208 BASF Wyandotte Corporation (1978) Residues of Bentazon, 6- and 8-
Hydroxy Bentazon in Succulent Beans and Peas. (Unpublished
study received Jun 5, 1979 under 7969-45; CDL:238951-D)
00031796 Lorberg, J.; Lorberg, J.; Lannon, M.; et al. (1976) Summary of
U.S. Crop Residue.Data for Vernam + Basagran on Soybeans. (Un-
published study received Aug 11, 1976 under 476-2155; prepared
in cooperation with Stewart Brothers and Morse Laboratories,
Inc., submitted by Stauffer Chemical Co., Richmond, Calif.;
CDL:225431-G)
j
00039278 Mahoney, M.D.; Penner, D. (1975) Bentazon transl-ocation and metab-
olism in soybean and navy bean. Weed Science^ 23(4) :265-271.
(Also in unpublished submission received Oct "30, 1975 under
6G1697; submitted by BASF Wyandotte Corp., Parsippany, N.J.;
CDL:094826-B)
00039279 Mahoney, M.D.; Penner, D. (1975) The basis for Bentazon selectiv-
ity in navy bean, cocklebur, and black nightshade. Weed Science
23(4):272-276. (Also in unpublished submission received Oct
30, 1975 under 6G1697; submitted by BASF Wyandotte Corp., Par-
sippany, N.J.; CDL.-094826-C)
75
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OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Bentazon/Sodium Bentazon Standard
MRID CITATION
00039280 Clark, J.R.; Portnoy, C.E.; Norris, F.A. (1975) 1974 Michigan Field
Metabolism Study: Bentazon Soybean Metabolism—Plots 7-11: Part
IIA. Total Residue Analysis of Plants: Laboratory Report No. PM-
5. (Unpublished study received Oct 30, 1975 under 6G1697; sub-
mitted by BASF Wyandotte Corp., Parsippany, N.J.; CDL:094S26-D)
00039281 Portnoy, C.E.; DiPrima, S.J.; Clark, J.R. (1975) 1974 Michigan
Field Metabolism Study: Bentazon Soybean Metabolism—Plots 7-11:
Part IIIB. Characterization of the Extractable Residues from
Soybean Tissues: 1. Soybean Grain: Laboratory Report No. PM-5.
(Unpublished study received Oct 30, 1975 under 6G1697; submit-
ted by BASF Wyandotte Corp., Pasrsippany, N.J.; CDL:094826-E)
00039282 Portnoy, C.E.; Clark, J.R.; Norris, F.A.; et al. (1975) 1974 Mich-
igan Field Metabolism Study: Plot 12—Navy Bean Plants: Part
IIB. Total Residue Analysis of Plants: Laboratory Report No. PM-
9. (Unpublished study received Oct 30, 1975 under 6G1697; sub-
mitted by BASF Wyandotte Corp., Parsippany, N.J.; CDL:094826-F)
00039283 Portnoy, C.E.; Norton, W.E.; Voulgaris, ?; et al. (1975) 1974 Mich-
igan Field Metabolism Study: Plot 12—Navy Bean Plants: Part
IIIB. Characterization of the Extractable Residues from Navy
Bean Plants: Laboratory Report No. PM-9. (Unpublished study
received Oct 30, 1975 under 6G1697; submitted by BASF Wyandotte
Corp., Parsippany, N.J.; CDL:094826-G)
00039284 Portnoy, C.E.; Clark; J.R.; Norris, F.A.; et al. (1975) 1974 Mis-
sissippi Field Metabolism Study: Plot 13— Lima Bean Plants:
Part IIB. Total Residue Analysis of Plants: Laboratory Report
No. PM-8. (Unpublished study received Oct 30, 1975 under
6G1697; submitted by BASF Wyandotte Corp., Parsippany, N.J.;
CDL:094826-H)
00039285 Portnoy, C.E.; Horton, W.E.; Voulgaris, ?; et al. (1975) 1974 Mis-
sissippi Field Metabolism Study: Plot 13—Lima Bean Plants:
Part IIIB. Characterization of the Extractable Residues from
Lima Bean Plants: Laboratory Report No. PM-8. (Unpublished
study received Oct 30, 1975 under 6G1697; submitted by BASF
Wyandotte Corp., Parsippany, N.J.; CDL:094826-I)
00039290 Horton, W.E.; Portnoy, C.E.; Otto, S. (1975) Additional Data on
the Freezer Storage Stability of Bentazon and Its 6.- and 8-Hy-
droxy Conjugates in Soybeans: Report No. SR-26. (Unpublished
study received Oct 30, 1975 under 6G1697; submitted by BASF
Wyandotte Corp., Parsippany, N.J.; CDL:094826-N)
76
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OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Bentazon/Sodium Bentazon Standard
MRID CITATION
00039656 BASF Wyandotte Corporation (1974) Abstract of the Metabolism of
Bentazon in Soybeans. Summary of studies 094134-C through
094134-L and 094134-N through 094134-S. (Unpublished study re-
ceived Jul 1, 1974 under 5F1529; CDL:094134-B)
00039657 Analytical Development Corporation (1974) Fate of Bentazon after
Application to Soybeans: Project ADC-101. (Unpublished study
received Jul 1, 1974 under 5F1529; submitted by BASF Wyandotte
Corp., Parsippany, N.J.; CDL:094134-C)
00039658 Cannizzaro, R. (1974) Determination of Bentazon..., 8-Hydroxy-
bentazon...and 6-Hydroxy-bentazon...Residues in Whole Soybean
Plants or Foliage and Soybean Grain. Analytical method no. 11
dated Apr 15, 1974. (Unpublished study received Jul 1, 1974
under 5F1529; submitted by BASF Wyandotte Corp., Parsippany,
N.J.; CDL:094134-D)
00039659 Penner, D. (1973) Rapid Metabolism of Bentazon in Soybean. (Un-
published study received Jul 1, 1974 under 5F1529; prepared by
Michigan State Univ., Dept. of Crop and Soil Sciences, submit-
ted by BASF Wyandotte Corp., Parsippany, N.J.; CDL:094134-E)
00039660 Penner, D. (19??) Selectivity of Bentazon between Soybean and Can-
ada Thistle. (Unpublished-study received Jul 1, 1974 under
5F1529; prepared by Michigan State Univ., Dept. of Crop and
Soil Sciences, submitted by BASF Wyandotte Corp., Parsippany,
N.J.; CDL:094134-F)
00039661 Mahoney, M.D. (1974) Bentazon Selectivity and Metabolism. Mas-
ter's thesis, Michigan State Univ.; Dept. of Crop and Soil Sci-
ences. (Unpublished study received Jul 1, 1974 under 5F1529;
submitted by BASF Wyandotte Corp., N.J.; CDL:094134-G)
00039664 Penner, D. (1973) Report on Bentazon Translocation in Higher
Plants. (Unpublished study received Jul 1, 1974 under 5F1529;
prepared by Michigan State Univ., Dept. of Crop and Soil Sci-
ences, submitted by BASF Wyandotte Corp., Parsippany, N.J.;
CDL:094134-J)
00039665 Otto, S.; Drescher, N.; Beutel, P. (1973) Newer Results on the
Metabolism of Bentazon in Soybeans (1. Report): Lab. Report
No. 1171. (Unpublished study received Jul 1, 1974 under 5F1529;
prepared by BASF, AG, submitted by BASF Wyandotte Corp., Par-
sippany, N.J.; CDL:094134-K)
77
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OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Bentazon/Sodiurn Bentazon Standard
MRID CITATION
00039666 Rogers, R.L.; Zaunbrecher, S.J. (1972) Absorption and Transloca-
tion of Bentazon in Soybean Plants. (Unpublished study received
Jul 1, 1974 under 5F1529; prepared by Louisiana State Univ.,
Agricultural Experiment Station, submitted by BASF Wyandotte
Corp., Parsippany, N.J.; CDL:094134-L)
00039667 Otto, S. (1974) Determination of the Optimum Time of Hydrolysis
for the Cleavage of Conjugated Bentazon Metabolites in Soybeans
Using ZN Methanolic HC1: Lab. Comm. No. 724. (Unpublished study
received Jul 1, 1974 under 5F1529; prepared by BASF, AG, sub-
mitted by BASF Wyandotte Corp., Parsippany, N.J.; CDL:094134-N)
00039668 Roger, J.C. (1974) Report: Determination of Residues in Soybeans .
Treated with Radioactive BAS 351-H: Laboratory No. E-7442. (Un-
published study received Jul 1, 1974 under 5F1529; prepared by
Cannon Laboratories, Inc., submitted by BASF Wyandotte Corp.,
Parsippany, N.J.; CDL:094134-0)
00039669 Otto, S. (1973) Results from an Experiment Conducted at LSU on
the Metabolism of Bentazon in Soybeans: Report No. 1177. (Un-
published study received Jul 1, 1974 under 5F1529; prepared in
cooperation with BASF, AG and Louisiana State Univ., submitted
by BASF Wyandotte Corp., Parsippany, N.J.; CDL:094134-P)
00039670 Otto, S.; Beutel, P. (1974) Further Investigation on the Metab-
olism of Bentazon in Soybeans: Lab. Report No. 1211. (Unpub-
lished study received Jul 1, 1974 under 5F1529; prepared in
cooperation with BASF, AG and Louisiana State Univ., submitted
by BASF Wyandotte Corp., Parsippany, N.J.; CDL:094134-Q)
00039671 Penner, D. (1973) Analysis of 14C-Bent'azon Residue from Soybeans
Provided by Cannon Laboratories. (Unpublished study received
Jul 1, 1974 under 5F1529; prepared by Michigan State Univ.,
Dept. of Crop and Soil Sciences, submitted by BASF Wyandotte
Corp., Parsippany, N.J.; CDL:094134-R)
00039672 Otto, S.; Beutel, P. (1974) Recent Results on the Metabolism of
Bentazon in Soybeans (2. Communication): Lab. Report No. 1199.
(Unpublished study received Jul 1, 1974 under 5F1529; prepared
by BASF, AG, submitted by BASF Wyandotte Corp., Parsippany,
N.J.; CDL:094134-S)
00039848 BASF Wyandotte Corporation (1972?) Metabolism of Bentazon in Ani-
mals. (Unpublished study received Jul 1, 1974 under 5F1529;
CDL.-094133-A)
78
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OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Bentazon/Sodium Bentazon Standard
MRID CITATION
00039849 Gilman, M,R.; Joseph, T.C. (1973) Report: Determination of Residues
in Milk and Tissues of Lactating Cows following the Oral Admin-
istration of Radioactive Bas 351-H: Laboratory No. E-6109. (Un-
published study received Jul 1, 1974 under 5F1529; prepared.by
Cannon Laboratories, Inc., submitted by BASF Uyandotte Corp.,
Parsippany, N.J.; CDL:094133-B)
00039850 Joseph, T.C. (1974) Report: Determination of Residues in Milk and
Tissues of a Lactating Cow following the Oral Administration of
Radioactive Bas 351-H: Laboratory No. E-9528. (Unpublished
study received Jul 1, 1974 under 5F1529; prepared by Cannon
Laboratories, Inc., submitted by BASF Wyandotte Corp., Parsip-
pany, N.J.; CDL:094133-C)
00039851 Analytical Development Corporation (1974) Fate of Bentazon after
Oral Administration to a Lactating Cow: Project ADC-114-A.
Includes analytical method no. 10 dated Jun 10, 1974. (Unpub-
lished study received Jul 1, 1974 under 5F1529; submitted by
BASF Wyandotte Corp., Parsippany, N.J.; CDL:094133-D)
00039852 Otto, S. (1972) Complimentary Investigations on the Metabolism of
Bentazon (Bas 351-H) in Soybeans (Experiments Dealing with the
Potential Cleavage of Bound Metabolic Complexes by Rumen Fluid):
Laboratory Report No. 1103. Translated by H. von Amsberg. (Un-
published study received Jul 1, 1974 under 5F1529; prepared by
BASF, AG, submitted by BASF Wyandotte Corp., Parsippany, N.J.;
CDL:094133-E)
• *«
00039853 Joseph, T.C. (1974) Report: Determination of Residues in Tissues,
Urine and Feces of a Goat and Rat following the Oral Administra-
tion of Methanol Insoluble HC-Residues Present in 14C Bas 351-H
Treated Soybeans: Laboratory No. E-7443. (Unpublished study
received Jul 1, 1974 under 5F1529; prepared by Cannon Labora-
tories, Inc., submitted by BASF Wyandotte Corp., Parisppany,
N.J.; CDL:094133-F)
00039854 Clark, J.R.; Wilson, L.A. (1974) Determination of Metabolic Prod-
ucts Produced by Nubian Goat after Oral Administration of
Methanol-Insoluble HC-Residues Present in Bentazon Treated Soy-
beans: Report No. PM-2. (Unpublished study received Jul 1, 1974
under 5F1529; submitted by BASF Wyandotte Corp., Parsippany,
N.J.; CDL:094133-G)
79
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OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Bentazon/Sodium Bentazon Standard
MRID CITATION
00039855 Joseph, T.C. (1974) Report: Determination of Residues in Egg and
Tissues of Laying Hens following the Oral Administration of
Radioactive Bas 351-H: Laboratory No. E-6949. (Unpublished
study received Jul 1, 1974 under 5F1529; prepared by Cannon
Laboratories, Inc., submitted by BASF Wyandotte Corp., Parsip-
pany, N.J.; CDL:094133-H)
00039856 Joseph, T.C. (1974) Report: Determination of Residues in Egg and
Tissues of Laying Hens following the Oral Administration of
Radioactive Bas 351-H: Laboratory No. E-9551. (Unpublished
study received Jul 1, 1974 under 5F1529; prepared by Cannon
Laboratories, Inc., submitted by BASF Wyandotte Corp., Parsip-
pany, N.J.; CDL:094133-I)
00039857 Analytical Development Corporation (1974) Fate of Bentazon after
Oral Administration to Poultry: Project ADC-114-B. Includes
analytical method no. 10 dated Jun 10, 1974. (Unpublished study
received Jul 1, 1974 under 5F1529; submitted by BASF Wyandotte
Corp., Parsippany, N.J.; CDL:094133-J)
00039860 Otto, S. (1974) Investigations of Rabbit Urine and Feces after Oral
Administration of 14C Bentazon: Laboratory Report No. 1203.
(Unpublished study received Jul 1, 1974 under 5F1529; prepared
by BASF, AG, submitted by BASF Wyandotte Corp., Parsippany,
N.J.; CDL:094133-N)
00039861 Roger, J.C. (1974) Metabolism and Balance Study of 14C-Bas 351-H
in a Rabbit: Experiment # 4E-1352-A. (Unpublished study re-
ceived Jul 1, 1974 under 5F1529; prepared by Cannon Laborato-
ries, Inc., submitted by BASF Wyandotte Corp., Parsippany, N.J.;
CDL:094133-0)
00039862 Booth, G.M. (1974) Metabolism of Bentazon in the Mouse (Mus-
musculus). (Unpublished study received Jul 1, 1974 under
5F1529; prepared by Brigham Young Univ., Dept. of Zoology, sub-
mitted by BASF Wyandotte Corp., Parsippany, N.J.; CDL:094133-P)
00040110 Cannon Laboratories, Incorporated (1974) Analytical Data and Cal-
culations for Results Found in the Text: Report E-9528. (Un-
published study received Jul 1, 1974 under 5F1529; CDL:094132-B)
00040111 Cannon Laboratories, Incorporated (1974) Analytical Data and Cal-
culations for Results Found in the Text: Report E-7443. (Un-
published study received Jul 1, 1974 under 5F1529; CDL:094132-C)
80
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OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Bentazon/Sodium Bentazon Standard
MRID CITATION
00040171 Eschbach, J.C.; Tietjens, F.; Hanes, R.E.; et al. (1974) Determina-
tion of Bentazon and 6+8-Hydroxy Metabolites in Hybrid Sweet
Corn from Greenville, Miss.: Field Experiment No. 73-11. (Un-
published study received Jul 1, 1974 under 5F1529; prepared in
cooperation with United States Testing Co., Inc., submitted by
BASF Wyandotte Corp., Parsippany, N.J.; CDL:094i26-A)
00040172 Eschbach, J.C.; Tietjens, F.; Hanes, R.E.; et al. (1974) Determina-
tion of Bentazon and 6+8-Hydroxy Metabolites in Soybean Grain
from Greenville, Miss.: Field Experiment No. 71-13-1. (Unpub-
lished study received Jul 1, 1974 under 5F1529; prepared in co-
operation with United States Testing Co., Inc., submitted by
BASF Wyandotte Corp., Parsippany, N.J.; CDL:094126-B)
00040173 Eschbach, J.C.; Daniel, J.W. (1974) Determination of Bentazon and
6+8-Hydroxy Metabolites in Soybean Grain from Wilson, Arkansas:
Field Experiment No. I-B-3-71. (Unpublished study received Jul
1, 1974 under 5F1529; submitted by BASF Wyandotte Corp., Parsip-
pany, N.J.; CDL:094126-C)
00040174 Eschbach, J.C.; Tietjens, F.; Hanes, R.E. (1974) Determination of
Bentazon and 6+8-Hydroxy Metabolites in Soybean Grain from
Greenville, Miss.: Field Experiment No. 72-99. (Unpublished
study received Jul 1, 1974 under 5F1529; prepared in cooperation
with United States Testing Co., Inc., submitted by BASF Wyan-
dotte Corp., Parsippany, N.J.; CDL:094126-D)
00040176 Eschbach, J.C.; Weishar, A.L.; Wilson, L.; et al. (1974) Determina-
tion of Bentazon and 6+8-Hydroxy Metabolites in Soybean Forage
and Grain from Waukee, Iowa: Field Experiment No. IV-B-5-72.
(Unpublished study received Jul 1, 1974 under 5F1529; submitted
by BASF Wyandotte Corp., Parsippany, N.J.; CDL:094127-B)
00040177 Eschbach, J.C.; Tietjens, F.; Bonner, W.P.; et al. (1974) Determi-
nation of Bentazon and 6+8-Hydroxy Metabolites in Soybean Grain,
Meal & Oil from Greenville, Miss.: Field Experiment No. 73-13.
(Unpublished study received Jul 1, 1974 under 5F1529; prepared
in cooperation with United States Testing Co., Inc. and Texas
Engineering Experiment Station, Cottonseed Products Research
Laboratory, submitted by BASF Wyandotte Corp., Parsippany, N.J.;
CDL:094127-C)
00040178 Eschbach, J.C.; Hendrick, L.W.; Carter, C.; et al. (19.74) Determi-
nation of Bentazon and 6+8-Hydroxy Metabolites in Soybean Grain
from Bird Island, Minnesota: Field Experiment No. III-B-202-73.
(Unpublished study received Jul 1, 1974 under 5F1529; submitted
by BASF Wyandotte Corp., Parsippany, N.J.; CDL:094128-A)
81
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OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Bentazon/Sodium Bentazon Standard
MRID CITATION
00040180 Eschbach, J.C.; Ascheman, R.E.; DiPrima, S.; et al. (1974) Determi-
nation of Bentazon and 6+8-Hydroxy Metabolites in Soybean Grain
from Adel, Iowa: Field Experiment No. IV-B-206-73. (Unpublished
study received Jul 1,"1974 under 5F1529; submitted by BASF Wy-
andotte Corp., Parsippany, N.J.; CDL:094128-C)
00040181 Eschbach, J.C.; Daniel, J.W.; Wilson, L.; et al. (1974) Determina-
tion of Bentazon and 6+8-Hydroxy Metabolites in Soybean Grain
from Keiser, Arkansas: Field Experiment No. VIII-B-28-73. (Un-
published study received Jul 1, 1974 under 5F1529; submitted by
BASF Wyandotte Corp., Parsippany, N.J.; CDL:094128-D)
00040182 Eschbach, J.C.; Thompson, J.; Hanes, R.E.; et al. (1974) Determina-
tion of Bentazon and 6+8-Hydroxy Metabolites in Soybean Grain
from Marion Co., South Carolina: Field Experiment No. VII-A-62-
73. (Unpublished study received Jul 1, 1974 under 5F1529; pre-
pared in cooperation with United States Testing Co., Inc., sub-
mitted by BASF Wyandotte Corp., Parsippany, N.J.; CDL:094128-E)
00040183 Eschbach, J.C.; Carter, C.; Hendrick, L.W.; et al. (1974) Determi-
nation of Bentazon and 6+8-Hydroxy Metabolites in Soybean For-
age, Straw, and Grain from Prior Lake, Minnesota: Field Experi-
ment No. III-B-6-72. (Unpublished study including published
data, received Jul 1, 1974 under 5F1529; prepared in cooperation
with Harris Laboratories, Inc. and Univ. of Minnesota, Agricul-
tural Experiment Station, submitted by BASF Wyandotte Corp.,
Parsippany, N.J.; CDL:094128-F)
00040184 BASF Wyandotte Corporation (1974) Summary of Bentazon, 8-Hydroxy-
Bentazon, and 6-Hydroxy-Bentazon Residues in Soybean Foliage,
Straw, Grain, Meal, Crude;0il, and Rotational Crops: Methods and
Results. (Unpublished study received Jul 1, 1974 under 5F1529;
CDL:094129-A)
00040185 Cannizzaro, R.I. (1974) Determination of Bentazon [3-Isopropyl-lH-
2,l,3-benzothiadiazin-4-(3H)-one 2,2-dioxide], 8-Hydroxy-Benta-
zon [8-Hydroxy-3-isopropy1-1H-2,l,3-benzothiadiazin-4-(3H)-one
2,2-dioxide], and 6-Hydroxy Bentazon [6-Hydroxy-3-isopropyl-lH-
2,l,3-benzothiadiazin-4-(3H)-one 2,2-dioxide] Residues in Whole
Soybean Plants of Foliage and Soybean Grain. Method no. 11A
dated Jun 25, 1974. (Unpublished study received Jul 1, 1974 un-
der 5F1529; prepared in cooperation with Analytical. Development
Corp. and others, submitted by BASF Wyandotte Corp., Parsippany,
N.J.; CDL:094129-B)
82
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OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Bentazon/Sodium Bentazon Standard
MRID CITATION
00040186 Cannizzaro, R.I. (1974) Determination of Bentazon, 8-Hydroxy Benta-
zon and 6-Hydroxy Bentazon Residues in Soybean Meal and Soybean
Oil. Method no. 12 dated Jun 25, 1974. (Unpublished study re-
ceived Jul 1, 1974 under 5F1529; prepared in cooperation with
Analytical Development Corp., submitted by BASF Wyandotte Corp.,
Parsippany, N.J.; CDL:094129-C)
00040187 Cannizzaro, R.I. (1974) Specificity of BWC Agricultural Chemicals
Method No. 11 for the Determination of Bentazon, 8-Hydroxy-Bent-
azon and 6-Hydroxy-Bentazon Residues in Soybean Foliage, Straw,
Grain, and Method No. 12 for Residues in Soybean Meal and Crude
Oil by Gas Chromatography: Report No. SR-2. (Unpublished study.
received Jul 1, 1974 under 5F1529; submitted by BASF Wyandotte
Corp., Parsippany, N.J.; CDL:094129-D)
00040188 Otto, S. (1974) Hydrolysis of Conjugated 6- and 8-Hydroxy-Bentazon
with 2N HC1 Anhydrous Methanol: Investigation of Optimum Time of
Hydrolysis and Hydrolytic Consistency: Report No. SR-3. (Unpub-
lished study received Jul 1, 1974 under 5F1529; submitted by
BASF Wyandotte Corp., Parsippany, N.J.; CDL:094129-E)
00040189 Otto, S. (1974) Freezer Storage Stability of Bentazon and Its 6-
and 8-Hydroxy Conjugates in Soybeans: Report No. SR-4. (Trans-
lation, unpublished study received Jul 1, 1974 under 5F1529;
prepared by Analytical Development Corp., submitted by BASF Wy-
andotte Corp., Parsippany, N.J.; CDL:094129-F)
t •* «
00040193 Wilson, L.A. (1974) Statistical Evaluation of BWC Ag. Chem. Methods
11A and 12 Based upon Recovery Studies from Soybean Foliage,
Grain, Straw, Meal, and Oil: Report No. SR-9. (Unpublished
study received on unknown date under 5F1529; submitted by BASF
Wyandotte Corp., Parsippany, N.J.; CDL:094129-J)
00040204 Drescher, N.; Otto, S. (1973) Degradation of Bentazon (Bas 351-H)
in Soil: Report No. 1140. 2nd rept. (Translation; unpublished
study received Jul 1, 1974 under 5F1529; submitted by BASF
Wyandotte Corp., Parsippany, N.J.; CDL:094131-D)
00040208 Drescher, N.; Otto, S. (1973) Degradation of Bentazon (Bas 351-H)
in Soil (3rd Report): Report No. 1149. (Trans,!ation; unpub-
lished study received Jul 1, 1974 under 5F1529; prepared by
BASF, AG, submitted by BASF Wyandotte Corp., Parsippany, N.J.;
CDL:094131-H)
83
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OFFICE OF PESTICIDE PROGRAMS
REGISTRATION STANDARD BIBLIOGRAPHY
Citations Considered to be Part of the Data Base Supporting
Registrations Under the Bentazon/Sodium Bentazon Standard
MRID CITATION
00040516 BASF Wyandotte Corporation (1975) Metabolism in Crops: [Bentazon].
Summary of studies 094825-B through 094825-D, 094825-F, 094825-
H and 094825-J. (Unpublished study received Oct 30, 1975 under
661697; CDL:094825-A)
00040517 Clark, J.R.; Portnoy, C.E.; Norris, F.A.; et al. (1975) 1974 Michi-
gan Field Metabolism Study: Bentazon Soybean Metabolism—Plots
7-11: Laboratory Report No. PM-5. (Unpublished study received
Oct 30, 1975 under 6G1697; submitted by BASF Wyandotte Corp.,
Parsippany, N.J.; CDL:094825-D)
00040518 Portnoy, C.E.; Clark, J.R.; Norris, F.A.; et al. (1975) 1974 Michi.-
gan Field Metabolism Study: Plot 12—Navy Bean Plants: Laborato-
ry Report No. PM-9. (Unpublished study received Oct 30, 1975
under 6G1697; submitted by BASF Wyandotte Corp., Parsippany,
N.J.; CDL:094825-F)
00040519 Portnoy, C.E.; Clark, J.R.; Norris, F.A.; et al. (1975) 1974 Mis-
sissippi Field Metabolism Study: Plot 13—Lima Bean Plants: Lab-
oratory Report No. PM-8. (Unpublished study received Oct 30,
1975 under 6G1697; submitted by BASF Wyandotte Corp., Parsippa-
ny, N.J.; CDL:094825-H)
00040520 BASF Wyandotte Corporation (1975) Residue Data & Methodology: [Ben-
tazon]. Summary of studies 094825-K through 094825-N. (Unpub-
lished study received Oct 30, 1975 under 6G1697; CDL:094825-J)
00040521 BASF Wyandotte Corporation (1975) Determination of Bentazon..., 8-
Hydroxy Bentazon..., and 6-Hydroxy Bentazon...Residues in Seed
and Pod Vegetable Forage, Hay, Pods, and Seeds. Method no. 19
dated Oct 24, 1975. (Unpublished study received Oct 30, 1975
under 6G1697; prepared in cooperation with Analytical Develop-
ment Corp. and BASF, AG; CDL:094825-K)
00040522 Horton, W.E.; Portnoy, C.E. (1975) Specificity of BWC Agricultural
Chemicals Method No. 19 for the Determination of Bentazon, 8-Hy-
droxy Bentazon and 6-Hydroxy Bentazon Residues in Seed and Pod
Vegetable Forage, Hay, Pods and Seeds: Report No. SR-24. (Un-
published study received Oct 30, 1975 under 6G1697; submitted by
BASF Wyandotte Corp., Parsippany, N.O.; CDL:094825-L)
00040785 Nilles, G.P.; Zabik, M.J. (1974) Photochemistry of Bioactive Com-
pounds: Multiphase Photodegredation and Mass Spectral Analysis
of Basagran. (Unpublished study received Jul 1, 1974 under
5F1529; prepared by Michigan State Univ., Pesticide Research
Center and Depts. of Entomology and Chemistry, submitted by
BASF Wyandotte Corp., Parsippany, N.J.; CDL:094138-C)
84
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