Prioritization of Pesticide Chemical Active Ingredients (PAIs) Based on Commonly Known Enviromental Characteristics


Prioritization of Pesticide Active Ingredients (PAIs)
          Based on Commonly Known
         Environmental Characteristics
               DRAFT REPORT
                 May 3, 1990
       U.S. Environmental Protection Agency
      Office of Water Regulations and Standards
    Assessment and Watershed Protection Division
               401 M Street,  S.W.
             Washington, D.C. 20460

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TABLE OF CONTENTS
EXECUTIVE SUMMARY
1.
INTRODUCTION
1
2.
METHODOLOGY
2
2.1 Environmental Parameters
3
2.2 Scoring System
6
3.
DATA SOURCES
8
4.
SUMMARY OF RESULTS
9

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LIST OF TABLES
Table No. Title Page No .
ES-i Top 20 Ranked Pesticide Active Ihgredients iii
1 Prioritization of Pesticide Active Ingredients 10
2 Top 20 Ranked Pesticide Active Ingredients 15
3 Pesticide Active Ingredients Recommended
for Further Testing and Research 16

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LIST OF FIGURES
Number Title Page No
ES-i Distribution of Hazard Scores for 270 Pesticide Active Ingredients i
1 Distribution of Hazard Scores for 270 Pesticide Active Ingredients 15

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EXECUTIVE SUMMARY
This report has been prepared to provide environmental guidance on proposed
effluent limitations guidelines for the pesticide manufacturing industry. This guidance is
provided by the overall ranking of water-related hazards for 270 pesticide active ingredients
(PAls) using common fate and effect parameters. The ranking is for the purpose of prelinünaiy
screening of chemicals for further research and risk assessment.
The method used for this ranking report is a modification of methods developed for
the U.S. Environmental Protection Agency (EPA), Criteria and Standards Division, in 1986.
Modifications, to the current ranking, tailor and refine methods to best fit the pesticide chemicals
and to meet project goals.
Two extensive data gathering efforts for the 270 PAls were undertaken in 1988 and
1990 to update the Toxic Data Base (the data base housing the pesticide data) with considerable
success in terms of data acquisition. An increase of over 500 data points for the environmental
parameters used in ranking (freshwater acute values, human health values, oral mammalian
toxicity values, bioconcentration factors, and Henry’s Law Constants) were achieved. To allow
the ranking of PAls, each
of the parameters were
assigned a scoring system
coverting ranges of values
to numerical scores.
Overall hazard scores
ranged from -5 (Naptalam-
-a herbicide) to 42
(Endrin--a priority
pollutant) for the 270 PAls
evaluated. (See Figure ES-i.) A maximum hazard score of 49 is possible. To investigate top
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ranking PAls and to attempt to validate the ranking scheme, the top 20 PAls were further
analyzed. Table ES-i shows the results of this analysis, indicating that 17 of the top 20 ranked
PATs are insecticides, 5 are priority pollutants, 14 have use restrictions (cancellations, bans,
restrictive use designations), and 11 have aquatic hazard labeling indicating acute risk to aquatic
organisms. These statistics show that the top ranking PATs are a high risk in terms of aquatic
hazard, validating the ranldng scheme.
In addition to providing a prioritization of hazard, this ranking analysis indicated
50 PAls where three or more ranking parameters had no data. These PAls are recommended
for further research and testing to fill data gaps that will allow the proper evaluation of hazard.
II

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Table ES- 1. Top 20 Ranked Pesticide Active Ingredients
No
CAS No.
Pollutant Name
Overall
Hazard
Score
Ure
Type,
Uae
Reatrictiona
Aquatic
Hazard
Labeling
1
72208
Endrin
42
INSECTICIDE
YES
NA
2
2104645
EPN\Sanlox
42
INSECTICIDE
NO
NA
3
298044
Dirulfoton
38
INSECTICIDE
YES
YES
4
298022
Pboratc\Famophoa\Thimct
38
INSECTICIDE
YES
YES
5
298000
Parathion methyl
37
INSECTICIDE
YES
YES
6
8065483
Dcmcton\Syatox
36
INSECTICIDE
YES
NA
7
55389
Fenthion BayIex
35
INSECTICIDE
NO
NA
8
57749
Cblordanc
34
INSECTICIDE
YES
NA
9
76448
Heptachlor’
34
INSECTICIDE
YES
NA
10
56382
Parathion ethyl
33
INSECTICIDE
YES
YES
11
58899
BHC, gamma-\Undaae
32
INSECTICIDE
YES
YES
12
70304
Hexachlorophene
32
FUNGICIDE
NO
NA
13
7786347
Mevinphoa’Pbosdrin
32
INSECTICIDE
YES
YES
14
81812
Warfano
32
RODENTICIDE
NO
NA
15
563122
Ethion\Bladan
30
INSECTICIDE
YES
YES
16
1582098
Trifluralin\Treflan
30
HERBICIDE
NO
YES
17
86500
Azinpho. methyl\Guthion, methyl-
29
INSECTICIDE
YES
YES
18
8001352
Toxaphenc
29
INSECTICIDE
YES
NA
19
116063
Aldicaxb\Temik
27
INSECTICIDE
YES
YES
20
2921882
ailorpynfo Duraban
27
INSECTICIDE
NO
YES
Priority pollutant.
lii

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1. INTRODUCTION
This report provides a ranking of the overall water-related hazards of 270 pesticide active
ingredients (PAls) potentially produced at pesticide manufacturing facilities. This report has
been prepared by the U.S. Environmental Protection Agency (EPA), Assessment and Watershed
Protection Division (AWPD), to provide environmental guidance to the Industrial Technology
Division (ITD) on proposed effluent limitations guidelines being developed for toxic discharges
in the Pesticide Chemicals Manufacturing Category.
This hazard ranking is based on readily available aquatic life, human health, mammalian
toxicity, and persistence parameters. Each parameter is assigned an individual score based on
its relative significance. Each parameter’s score, in turn, is summed for a PAT giving an overall
water-related hazard score that can be ranked highest to lowest. Although this ranking can be
useful in prioritizing functions, it should only be used as a preliminary screening device to
identify potential candidates for further detailed research or risk assessment. In addition, this
ranking identifies pesticides for which additional testing and literature research is needed to fill
data gaps and to allow the proper prioritizing of these chemicals.
In December 1988, AWPD produced a similar ranking report to assist lTD. Initially,
this report addressed environmental parameters on an individual basis. Later, an addendum was
added using a ranking/scoring system. This preliminary report had data gaps and lacked a
discussion of the results. This update of the ranking report incorporates new data and discusses
tabular results.
1

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2. METHODOLOGY
The methodology used in this study is a modification of methods used in a ranking system
originally developed for the Criteria and Standards Division (CSD). The CSD ranking assisted
in the listing and delisting of 307(a) priority pollutants and the planning of future activities.
Modifications to the current ranking methodology include (1) the selection of only five
parameters instead of ten based on their availability and pertinence for this specific study; (2)
modification of some of the scoring scenarios to better reflect specific concerns of this ranking;
and (3) the deletion of Tier II ranldng which deals with exposure of a PA l nationwide.
The five environmental parameters were chosen to best characterize water-related hazards
of PAls. These parameters were chosen for two main reasons: (1) parameters address specific
concerns outlined in Section 307 of the Clean Water Act (CWA); and (2) sufficient data are
available for these parameters to make the ranking meaningful.
Section 307 of the CWA identified specific concerns in regard to water-related hazards:
1. Toxicity;
2. Persistence;
3. Usual or potential presence of affected organisms;
4. Degradability;
5. Importance of affected organisms; and
6. Nature, extent, and magnitude of the toxic pollutants of such organisms.
This ranking focuses primarily on the first three concerns (concerns four through six are
too specific to be addressed using readily available environmental parameters). In order to
address these concerns, sufficient data must be available for chosen parameters to allow ranking.
For instance, the CSD ranking included hydrolysis as a parameter; however, it was dropped
from this ranking scheme because of lack of data. The five parameters chosen for ranking
2

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purposes are discussed in detail in Section 2.1- Environmental Parameters. The scoring systems
used for each of these parameters are presented in Section 2.2.
The number of PAls with environmental parameters available for ranldng is as follows:
• Freshwater Acute Toxicity Values: 233
• Human Health Values: 154
• Oral Mammalian Toxicity Values: 234
• Bioconcentration Factors: 236
• Henry’s Law Constants: 176
2.1 Environmental Parameters
The following five parameters were used in the ranking system:
Freshwater Acute Toxicity Values
This parameter addresses the toxicity and potential presence concerns outlined by Section
307 of the CWA. Values in this category measure the effect that a chemical has on aquatic
organisms in terms of direct mortality. Toxicity values are either EPA acute criteria developed
to protect sensitive species from acute effects of chemicals, or lowest reported LC (Lethal
Concentration Fifty) values indicating the concentration of a chemical that will kill 50 percent
of test organisms within a set length of time (often 96 hours). This category also indirectly
addresses the CWA concern of usual or potential presence of effected species” by using only
test species that are common resident species of organisms.
3

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Human Health Values - for the Ingestion of Water and Organisms
These values address toxicity concerns outlined in the CWA in terms of potential human
health impacts caused by the ingestion of contaminated water and aquatic organisms. Values are
either human health criteria or calculated benchmarks indicating levels in water that may cause
long-term toxicity or carcinogenic effects at typical levels of consumption (2 liters of water and
6.5 grams of fish daily). For toxicity protection, the human health value is calculated using the
above typical consumption, as well as the chemical Reference Dose (Rid--previously called
allowable daily intake) and the bioconcentration factor of the chemical. The calculation is as
follows: }IHVAL(ug/l) = Rfd(mg/d) x 1,000 ug/mg / [ 2 1 + 0.0065 kg/d x BCF(lJkg)]. For
carcinogenicity protection the value is calculated using the cancer potency slope (QP) at a l0
risk level: RHVAL(ug/l) 70 kg x lC ’ x 1,000 ug/mg I [ Q ((mgIkgId) 1 ) x [ 2 1 + 0.0065
kg/d x BCF(l/kg)]].
Oral Mammalian Toxicity (LD ) Values
Where information is insufficient to derive Rids for the calculation of human health
values, Lethal dose fifty (LD ) values can be used to judge the relative acute toxic effects to
warm blooded animals. Oral LD values represent the ingested dose of a substance expected
to kill 50 percent of a defined experimental animal population. Typical species used in these
tests include rats, mice, and guinea pigs.
Bioconcentatign Factors (.BCFs )
The bioconcentration factor can be an indication of persistence and chronic toxicity. The
BCF is a good indicator of a pollutant’s potential for accumulation to aquatic biota (usually fish)
through uptake across an external membrane’s surface. The BCF alone, however, does not
indicate the reversibility, and hence, the persistence of a chemical. However, when considering
pesticide and organic chemicals, process reversibility can be limited, allowing the BCF to act
4

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as a screening tool for potential persistence. Values reported in this ranking can be actual
values, derived from bioassay testing, or estimated values, calculated using correlation between
log P (log of the octanol/water partition coefficient) or the solubility of the chemical. Actual
values are for typical U.S. resident species. Methods for estimation are detailed in Lyman, et.
at., 1981. Values reported are the most conservative (largest) values taken from the available
literature. The following criteria were used when selecting values:
• Resident U.S. fish species axe preferred over bottom dwellers or estimated values.
• Bottom dwellers are preferred over estimated values.
• Edible tissue or whole fish values are preferred over non-edible or viscera values.
• Estimates derived for log P are preferred over solubiity or other estimates unless the
estimate comes from EPA criteria documents.
• Estimated values in excess of 1 million are reported at 1 million.
Bioconcentration factors can also be an indirect indication of adsorptibility to sediment.
BCFs can be correlated with the adsorption coefficient K . Hence, the higher the BCF, the
greater the potential for adsorption to bottom sediments.
Henry’s Law Constant
Henry’s Law Constant (H) addresses persistence by indicating volatility from water.
Henry’s Law Constant is the vapor pressure of the chemical in atmospheres divided by the
solubility in moles per cubic meter. Therefore, H can address exposure potential and is the only
category where a chemical can score negative points. A negative number is given to chemicals
that rapidly volatilize from water and would have a lower persistence and exposure potential.
5

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2.2 Scoring System
To allow the ranking of PAls, each of the parameters were assigned a scoring system
converting ranges of values to numerical scores. The scoring systems indicating potential
environmental concerns are as follows:
Acute Freshwater Aquatic Toxicity
Score CrileriaiToxicity Level (ugh )
12 <10
10 > 1-10
5 >10-100
3 > 100-1,100
0 >1,000
Human Health - Ingesting Water and Organisms Criteria
Score Criteria/Toxicity Level (ugh )
12 <1.0
10 > 1-10
5 >10-100
3 > 100-1,100
0 >1,000
Oral Mammalian Toxicity
Score Oral Toxicity (mg/kg )
12 <1.0
10 >1-5
5 >5-50
2 >50-500
0 >500
6

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Bioconcentration Factors
Score Bioconcentration Factor WIC )
8 4,000
6 700-3,999
4 300-699
2 100-299
0 <100
Henry’s Law Constant
Score Henry’s Law Constant (atm-m31 mole )
-5 >iO-
0 
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3. DATA SOURCES
Data used in the current ranking are from AWPD’s Toxics Data Base (TDB) of over
1,600 chemical pollutants. The TDB includes aquatic toxicity, human health, physical-chemical
properties, and other information compiled from over 100 references. Two extensive data
gathering efforts for the 270 PAls were undertaken in 1988 and 1990 to update the TDB. An
increase of over 500 data points for the environmental parameters was achieved. Major data
sources included the following:
• The Handbook of Acute Toxicity of Chemicals to Fish and Aquatic Invertebrates
(Johnson and Finley 1980).
• Annual literature reviews, prepared by the Water Pollution Control Federation (found
in the June 198 1-1988 issues of the JWPCF).
• The Pesticide Manual - A World Compendium (Worthing 1987).
• The AQIJIRE Data Base, 1988 and 1990 (Aquatic Toxicity)
• The Integrated Risk Information System, 1988 and 1990 (IRIS).
• The Manual of Acute Toxicity: Interpretation and Data Base for 410 Chemicals and
66 Species of Freshwater Animals, 1986.
• The Office of Pesticide Programs (OPP) Environmental Fate Branch Data Base
compiled from OPP file data.
• OPP file data.
• The Farm Chemicals Handbook, 1989.
• Handbook of Chemical Property Estimation Methods (Lyman et al., 1981).
• Condensed Chemical Dictionary, 1981.
8
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4. SUMMARY OF RESULTS
Table 1, Prioritization of Pesticide Active Ingredients, shows the results of the overall
ranking, prioritizing chemicals by hazard. Chemicals are sorted in descending order of potential
environmental hazard. Scores range from the lowest possible (-5) to 42. Forty-nine is the
maximum score achievable. Figure 1, Distribution of Hazard Scores for 270 Pesticide Active
Ingredients, indicates the hazard score distribution for the 270 PAls.
Table 2, Top 20 Ranked Pesticide Active Ingredients, gives further information for the
top 20 ranked PATs. These data indicate that out of the 20 PAls, 17 are insecticides, 14 have
use restrictions, and 5 are priority pollutants. Use restrictions may include bans, cancellations,
product discontinuations, or EPA restricted use status. In addition, at least 11 of these PAls
have aquatic hazard labeling, warning that the chemicals are toxic to fish and aquatic organisms.
Overall hazard scores for these 20 chemicals range from 27 (a score comparable to the priority
pollutant Aldrin) to 42 for the priority pollutant PAT Endrin and EPN/Santox. The statistics for
the top 20 PATs indicate that the water-related risk of these pesticides is high, validating the
ranking system as a viable screening tool.
Table 1 also shows that a number of pesticides do not have readily available information
from EPA or the literature. Fifty PATs have three or more parameter data gaps producing
potentially erroneous low hazard scores. Table 3, Pesticide Active Ingredients Recommended
for Further Testing and Research, presents the PATs for which further testing and research is
needed to adequately rank.
9
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TABLE 1. PRIORITIZATION OF PESTICIDE ACTiVE INGREDIENTS
No. CAS No. Pollutant Name
1 72208 Endrin
2 2104645 EPN\Santox
3 298044 Disulfoton
4 298022 Phoraix \Famophos \Thimet
5 298000 Parathion methyl
6 8065483 Dmncion\Syslox
7 55389 Fenthion\Baytex
8 57749 Chlordane
9 76448 1-leptachlor
10 56382 Parathion ethyl
I I 58899 BI- 1C, gamma- \Lindane
12 70304 Hexachlorophene
13 7786347 Mevinphoe Pboadnn
14 81812 Warfarm
15 563122 Ethion\Bladan
16 1582098 Triflurahn\Treflan
17 86500 Azinphoa methyl \ Guthion, methyl.
18 8001352 Toxaphene
19 116063 A1d icarb\T ik
20 2921882 O 1oi-pynfos\Dursban
21 115297 Endosulfan mixed liomars
22 3689245 Tetriethyldithiopyrophoephate
23 56724 Coumaphoa
24 78488 DEF
25 115902 FensulIothjon\Desanjt
26 950378 Methiadathion \Supr.cidc
27 13171216 Phosphxmidon\Dimecron
28 333415 Diazinon\Spectracide
29 78342 Dioxathion
30 51630580 Fenvaleraxe\Pydamn
31 944229 Fonofo
32 10453868 Resmetbnn
33 13071799 Terbufos CounIer
34 1563662 Carbofuran\Furadan
35 115322 Dicofol\Kelthane
36 959988 Endosulfan, alpha-
37 33213660 Endosullin, bet.i-
38 22224926 Fenamiphos
39 16752775 Melhomyl \ Lannate
40 60515 Cygon\Dimethoale
41 101053 Anilazme\Dyrene
42 62737 Dichlorvos
43 122145 Fenitrothion
44 133073 Folpet
45 72435 Methoxychlor
46 41198088 Profenofos\Curaoron
47 55285148 Carbosulfan
48 534521 Diniiro-o.crneol, 4.6-
49 55283688 Ethalfiuralin
50 121755 Malathion
51 10265926 Methamidophos
52 2032657 Methjoca,b
53 732116 Phosmet\Imjdan
54 52686 Trichlorofon \ Dylox
Fxesh- Human
water Health
Acute W&O
(ugh) (ugh)
018 0630
056 0008
390 060
060 2.30
014 7
14 056
062 4
2.40 000046
0520 00003
0065 73
2 00186
21 00090
0160 56
3430 7
0056 30
840 093
010 62
073 000071
50 44
008 10.6
022 74
160 16
0074
27 009
10 9
2.20 30
2.80 17
020 63
035 40
360 390
7 47
028 291
020
48 170
53 11
022 74
022 74
110 833
105 872
43 479
027
01 25
0003 80
39 3.30
05 185
080
15 83
66 1340
75
05 616
46,000 1 75
5 270
2 551
018 317
Oral llcuzy’i
LDSO BC? Law
(n (Ukg) Constant
130 3,970 40013-07
9 12,600 1 1013-09
2.60 460 2.6013-06
110 630 580E .06
5 71 55913.08
17 455 44013.08
190 2,300 20013-07
457 14,100 96313-06
147 15,700 8 1913-04
2 430 600E-07
59 1,400 2.3013-06
60 316,000 130E.10
3 0080 63013-11
3 125 2 .40E .12
2440 1,500 2.5013-06
500 1,200 2.2013.05
13 139 11013.07
80 22,000 43613-01
093 2 60013-09
135 2,729 44013.06
80 2,755 1 OOE .05
5 28 2 .90E -06
16 331 32013-08
200 3,050
470 40
25 46 2.2013-09
17 2 99013-12
76 34 73013-09
23 110
451 407 1 5013-07
794 150 52013-06
2,500 618 50013-09
160 29 800E .06
2 12 80013-09
668 25,000 1 60E-07
76 270 10013-05
240 270 10013-05
1530 154 57013-10
17 1 1 8013-10
180 67 IOOE-10
460 140 410E-09
56 32 3 50E-07
250 98 140E-06
10,000 618 4 OOE .06
2,500 2,600 15013.05
358 114 240E-07
185 990 520E-06
25 55 2.6013-07
10,000,000 4,800 1 8013-06
1.000 92 12013.07
30 009 2.8013-11
100 90 32013-09
113 83 75013-09
560 32 17013-11
Chemical Ranking
Acute W&O Oral BC? 11W TOTAL
12 12 10 6 2 42
12 12 5 8 5 42
10 12 10 4 2 38
12 10 10 4 2 38
12 10 10 0 5 37
5 12 10 4 5 36
12 10 2 6 S 35
10 12 2 8 2 34
12 12 2 8 0 34
12 5 10 4 2 33
10 12 2 6 2 32
5 12 2 8 5 32
12 5 10 0 5 32
5 10 10 2 5 32
12 5 5 6 2 30
10 12 2 6 0 30
12 5 5 2 5 29
12 12 2 8 .5 29
5 5 12 0 5 27
12 5 2 6 2 27
12 5 2 6 2 27
10 5 10 0 2 27
12 .- 5 4 5 26
5 12 2 6 — 23
5 10 10 0 •- 25
10 5 5 0 5 25
10 5 5 0 5 25
12 5 2 0 5 24
12 5 5 2 .- 24
10 3 2 4 5 24
10 5 5 2 2 24
12 3 0 4 5 24
12 — 10 0 2 24
5 3 10 0 5 23
5 5 0 8 5 23
12 5 2 2 2 23
12 5 2 2 2 23
3 10 5 0 5 23
10 3 5 0 5 23
5 10 2 0 5 22
12 - - 2 2 5 21
12 5 2 0 2 21
12 5 2 0 2 21
5 10 0 4 2 21
12 3 0 6 0 21
12 - . 2 2 5 21
5 5 2 6 2 20
5 5 5 0 5 20
10 .- 0 8 2 20
12 3 0 0 5 20
0 10 5 0 5 20
10 3 2 0 5 20
10 3 2 0 5 20
12 3 0 0 5 20
10
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TABLE 1. PRIOR1TIZATION OF PESTICIDE ACTIVE INGREDIENTS
No. CAS No. Pollutant Name
55 319857 BHC, beta.
56 510156 Qi1orob zilate
57 52645532 Pamethnn \Ambush \Pounce
58 121211 Pyrethnn l
59 8003347 Pyrethrms
60 83794 Rotmone\ Mexide
61 584792 Allethnn
62 470906 ø 1orfmvinphos\Supona
63 88857 Dinoscb\DNBP
64 150505 Maphoa\Folez
65 72560 Polhane\Ethylan
100 00163
600 90
2.30 1,680
140 375
140 375
2.60 84
2,1
219 62
32 16
1,300 0 190
4
820 15
400 137
1,400 00092
100 76
490 890
47 20
74
6,400 39
12
560 1,540
2.100
160 50
8,000 14
180
140 990
85 672
1,300 29
256
14.580 0 0008
0350 68
100 41
3.600
20
170
IS
70
430
69
150
600
700
SI
1 70
11
2,000
35
16
15
1.150
130 447E-07
700 2,093 390E-08
430 125 2.50E-08
584 840
584 840
132 181
480 2,500
10 37 550E-10
58 360 2.OOE-06
1,272 1,580
6.600 66,100
1,630
540
12,000
2,500
866
30
10.000
2,30
3,400
28
24
584
140
800
2,000
146
430
120
L230
12.40 5,000
1.010 210
440 290
In 37
450 5,000
572 4,000
5,000
289 300
170 650
270
190
850
53
73 288
65
400 4,640
980
26
0 129
500
369
1,800 585
210 60
3 12 -. 2 2
3 5 0 6 5
10 0 2 2 5
10 3 0 6 —
10 3 0 6 —
10 5 2 2 —
10 — 2 6 —
3 5 5 0 5
5 5 2 4 2
0 12 0 6
10 0 8 —
3 S 0 4 5
3 3 5 0 5
0 12 -- 2 2
3 5 0 6 2
3 3 5 0 5
5 5 0 6 0
5 — 0 6 5
O 10 0 0 5
5 — 5 0 5
10 0 0 0 5
O .. 10 0 5
3 5 0 2 5
0 5 S 0 5
10 .- 5 — —
10 3 0 2 —
5 3 2 0 5
0 5 0 4 5
3 — 0 6 5
0 12 2 0 0
12 5 2 0 -5
3 5 2 4
0 — 0 8 5
5 0 6 2
5 0 2 4 2
3 3 2 0 5
5 3 5 0
5 3 0 0 5
3 3 0 2 5
S — 0 6 2
3 3 2 0 5
3 3 0 2 5
3 — 2 2 5
5 3 2 2 —
10 0 0 2 0
S -- 2 0 5
0 5 2 0 5
5 — 2 0 5
5 3 0 2 2
5 -- 0 2 5
0 -- 5 2 5
-- -- 12 0 --
0 5 2 0 5
3 5 2 0 2
Fresh- Human
waler Health Oral Hcmy’s
Acute W&O LDSO BCF Law Chemical Ran ng
( ugh) (ugh) (mg/kg) (11kg) Constant Acute W&O Oral BCF HLC TOTAL
2,000 410 1 20E-08
34 6 370E-08
130 587E.06
1,100 450E-06
2 2.40E-10
1,043 618E-04
1,100 120E .09
10 630 .I3
26 300E.08
41 350E-09
10 1 50E-10
150 2.30E-08
75 760E-08
66 886500 T u
67 22781232 Bendiocarb\Ficam
68 319846 BHC, alpha-
69 5598130 Qilorpynfos methyl
70 23135220 Oxamyl VydaIe
71 82688 Pciitach1oroiut i -obcnzene\Quintozen
72 2439012 QumomethionatelOxyihioqtunox
73 30560192 Acephate
74 20232600 Aminocajb\Matacil
75 17804352 Benomyl \ Benlatc
76 82666 Diphacinone
77 330541 Diuron/DCMIJ
78 25311712 1sofenpho
79 58366 Pmne, I0,lO’.oxydi.
80 121299 Pyrethnnil
81 58902 Tetrachlorophenol, 2,3,4,6-
82 33089612 Amitraz
83 23184668 Butathlor
84 106934 Elhylenedibronude
85 300765 NaIad \Dibrom
86 2310170 Phosalone\Azofone
87 97234 Dichlocophon
88 42874032 Oxyfluorofen
89 87865 Pentachlorophenol
90 1918167 Propacalor
91 114261 Propoxw\Baygon
92 5902512 Terbacil
93 961115 Tcuacb1orvmpbo \Gardona \Surofoa
94 7696120 Tetramethrin\Neo.pynaznm
95 93765 Tnthlorophenoxyacetic acid. 2,4,5-
96 93721 Trichlorophenoxypropionic acid, 2,4,5-
97 741582 Bensulide\Betesan
98 1689845 Bromoxynil
99 63252 Carbazyl\Sevm
100 7700176 Cnnoxyphos\Ciodnn
101 21725462 Cyanazine
102 301122 Domelon-O-methylfl)xydemeton-meihyl
103 35367384 Diflubaizuron
104 39300452 Dinocap \ Karathane
105 13194484 Ethoprophos
106 81990336 KN Methyl
107 330552 Linuron
108 2212671 Molinale
19
19
19
19
19
19
18
18
18
18
18
17
16
16
16
16
16
16
15
15
15
15
15
15
15
15
15
14
14
14
14
14
13
13
13
13
13
13
13
13
13
13
12
12
12
12
12
12
12
12
12
12
12
12
127
93 L2OE-07
618 150E-07
1.300 800E-08
44 630E-04
7 330E.03
363
4.100 I 2L)E-12
1,800 950E-07
475 2.75E-06
14 920E-08
7
2 1 90E.10
284 I 80E.09
916 670E-07
65 2.96E-08
263 2.80E .07
267 2.IOE-08
140
260 1 1OE-05
13 590E.09
8 280E-12
02 910E-12
230 400E-07
283 480E-09
220 1 SOE.07
0004
76 6 60E-08
60 160E-06
412
1,820
11
-------
TABLE 1. PRIOR1TIZATION OF PESTICIDE ACTIVE INGREDIENTS
Na CAS No. Pollutant Name
109 40487420 Pendimethalin\Prowl
110 7287196 Prometyrn \Caparol
111 62748 Sodium fluo oacetaIe
112 2303175 Tn-alIate\Far-Go
113 1912249 Atrazine
114 117806 Diclilonc\Pbygon
115 145733 Endothall
116 2164172 Fluomewron
117 75605 Hydroxydimethylarsine oxide
118 12427382 Msncb\Vancide
119 19044884 Oryzahn
120 92842 Phenothiazinc
121 299843 Round
122 15972608 Alachlorf Lasso
123 834128 Amelryn
124 35400432 BoIs &\Su1profos
125 2425061 Captafol\Difolatan
126 133062 Captan
127 3691358 Oilorophac inone
128 1897456 C3ilomthaloml
129 1982474 C]ilorozinun
130 66819 Cyclolieximide
131 13684565 Desmediphazn\ Betanex
132 94757 Dichlorophenoxyacetic acid, 2,4-
133 122394 Diphenylamine
134 60168888 Fenarimol\Rubigan
135 33820528 Isopropalm
136 94746 MCPA
137 93652 MCPP\Mecoprop
138 315184 Mexacarba!e\Mexcarbole\Zeclran
139 1918021 Picloram
140 709988 Propanil
141 137268 Theum
142 43121432 Tnadunefon
143 1861401 BenTharalin/Benefln
144 40596696 Meihoprene
145 1610180 Prumeton\Pramttol
146 51350848 BBTAC
147 99309 Dicloran\Bouan
148 141662 Dicroiophos\Bidnn
149 14484641 Ferbam
150 94815 MCPB
151 21087648 Me nbuzin
152 25606412 PrevicwN
153 139402 Propazine
154 122349 Simazine
155 155044 Vancidc5lZ\Zesax
156 1929777 V&nolate
157 3244904 Aspon
158 319868 BHC,delta .
159 92524 Biphenyl
160 74839 Bromomethane
161 542756 Dichloiopropene, 1,3-
162 10061015 Dichloropropene, os-1,3-
Fiesh- Human
wafer Health Oral Henry’a
Acute W&O LD5O BCF Law
(ugh) (ugh) (mg/kg) (Iikg) Constant
420 296 1.050
2,500 73 3,150
0066
490 124 1,675
220 140 750
14 1,300
140 699 38
600 390 6,416
55 700
530 175 6,750
190 370 1,000
5,000
100 1,740
1.000 231 930
3,200 222 1,110
5,200 304
21 69 2,500
262 394 7,000
106
250 330 10,000
430 3,000
1,400 2
600 9,600
14,000 100
297
466
920 1 .500 44 470E-08
12.8
700 2,000 026
340 680 73
869 1,936 2 2.30E-09
699 2,000 030 2.IOE .09
450 7,700 99 1 80E-09
172 5,000 4.90 3.20E-10
41,700
30 1,500 49 300E .05
740 91 160E -06
1,000 130 2.07E-07
723 2,400 437
0190 39 IOOE-01
10 127 19 130E-03
87 127 19 130E -03
Chemical Ranking
Acute W&O Oral BCF ILLC TOTAL
3 3 0 6 0
0 5 0 2 5
— — 12 0 —
3 3 0 6 0
3 3 0 0 5
S — 0 6 -.
3 3 5 0 —
3 3 0 0 5
-. 5 0 6 —
3 3 0 0 5
3 3 0 0 5
0 6 5
3 -- 0 6 2
0 3 0 2 5
0 3 0 2 5
0 -. 2 6 2
5 5 0 0 —
5 3 0 0 2
— — 10 —
3 3 0 2 2
3 — 0 2 5
0 — 10 0
3 -. 0 2 5
0 3 2 0 5
— 3 -. 2 5
3 — 0 2 5
3 3 0 4 0
0 5 0 0 5
0 5 0 0 5
5 — 5 0 —
5 0 0 0 5
0 3 0 2 5
3 3 2 2 —
0 3 2 0 5
3 3 0 8 .5
0 3 0 4 2
0 3 0 6 0
— — - . 8 —
-. 3 0 0 5
3 — 5 — -.
5 3 0 0 —
5 3 0 0 —
0 3 0 0 5
0 3 0 0 5
0 3 0 0 5
0 3 0 0 5
-. -- 8
3 5 0 0 0
5 — 0 0 2
0 .. 0 2 5
0 3 0 4 --
0 12 0 -5
5 5 2 0 .5
5 5 2 0 .5
1200 370E-05
240 9 60E-09
05
800 1 20E .05
72 2.58E-09
2300
05
40 140E-09
1,658
0001 2.1OE -07
59 1 90E-08
840 4 70E-09
2,600 8 50E-06
158 3.20E -08
108 140E-09
1.006 9 1OE .07
2.7
36 120E .06
200 5 80E-07
283 1 7OE.10
2.3
179 1 30E-10
55 7 50E-08
269 1 47E.07
230 3.IOE .09
620 140E-05
14 480E.10
3 2.30E .09
31
054 450E-10
111 2iOE .08
114
7.60 4 1OE -09
4.700 1 70E .03
512 6.90E-06
1,100 1 bE-OS
151,400
2,500
182 5,000
17 700
87 930
14
2,400 2.000
130 1,285
128 375
880 363
540 2,000
790 5.000
120 3.000
12
12
12
12
11
11
11
11
11
11
II
11
11
10
10
10
10
10
10
10
10
10
10
10
10
10
10
I0
10
10
10
10
10
10
9
9
9
8
8
8
8
8
8
8
8
8
8
8
7
7
7
7
7
7
910
100
1,200
8,900
10
27
2,300
105
10.000
370
1,550
8,600
430
90
70
42,000
235.000
17,500
1.000
230
70
5,100
4,700
11.000
90
90
12
-------
TABLE 1. PRIOR flZATION OF PESTICIDE ACTIVE INGREDIENTS
No. CAS No. Pollutant Nanac
163 10061026 Dicliloropropene, ans-1,3-
164 2227170 Dienodilor\Pentac
165 2655154 Landnnl
166 2686999 Landnn ill Tnmethacsrb
167 13684634 Pheninrdipham \ Bentinal
168 2312358 Propargrte/BPPS
169 5915413 Terbuthylazine
170 1134232 Cyctoale
171 1861321 DCPA)Dacthal
172 2439103 Dodecylguanidmemonoicetate
173 4080313 Dowicil75
174 2593159 tradiazoIe
175 9006422 Metirain
176 26530200 Octhilinone
177 137304 Ziram\Cymaxc
178 50594664 Acifluorfen \ BIaz
179 314409 Bromacil
180 533744 Busamid\Dazomet\Mylone\Nefusan
181 21564170 Busanl2
182 128030 Busan85
183 2008415 Butylate
184 133904 1oramben
185 101213 Oilorpropham
186 117522 Coumafuryl
187 75990 Dalapon
188 94826 DB,2,4- salts andescea
189 1918009 Dicamba
190 52857 Famphw ’\Famophos
191 640197 Fluoroacetenude, 2-
192 7166190 thy-gird
193 1071836 Glyphosste\Roundup
194 1333240 Glyphosine
195 51235040 Hexazmone
196 4849325 Kazbuulaie
197 112561 Lethane384
198 569642 Malathite green
199 53780340 Mefluulide
200 137428 Metham sodlum\Vapam
201 51218452 Mexolac.hlor
202 150685 Monusun
203 140410 Monuron TCA
204 142596 Nabam
205 6317186 NalcoD .2303
206 15299997 Nap opamtdr
207 27314132 Norflurazon
208 37924132 Perfluidone
209 90437 Pbenylphenol, 0-
210 34014180 Tebuthiuron
211 3383968 Temephos\Abate
212 148798 Thiabendazole\Murtect
213 83261 Pindone
214 23564058 Thiophanate methyl
215 31512740 Busan77\PBE)
216 128041 Cirbam-S
Fresh- Human
water Health Oral Henry’.
Acute W&O LD5O BCP Law
( ugh) (ug/1) (rr /1cg) g) Constant
90 87 250 2 130E-03
3,160 270 2.40E-07
208 13 2.20E-07
208 13 2.20E-07
8,000 260 820E-13
220 228 7 OOE-04
2,000 165 660E .08
2,710 340 760E .06
3,000 480 2.2LIE-06
1,000 60
1.300
2.000 450 6 40E-07
2.400 2.800
1,470 1,280
700 1,400 0001
1,370 42 400E-09
5,200 24 1 OOE-10
520 68 200E-10
1,590
300
17,000
57,510
5,900
36
60
210 3,200
10,000 480
6.480 5,530
11,000 990
2,000 203
3,900 1,004
4,850
40,000
20
1,300 3,200
1,920 19 220E-07
1,800 0004
2,780 69 900E .09
3.600 18 5 70E-10
2,300 14 2.30E .10
395 0040
3
4.680 50 2.OOE-08
8,000 11 3 OOE-10
633 61 8 OOE-08
2,480 270
644 4 2.40E .10
8,600 55
3,300 68 2.1OE .11
280 121
3,000 304
0240
1.000 103
Chemical Ranking
Acute W&O Oral BCF HLC TOTAL
5 5 2 0
— -- 0 2
0 - . 2 0
0 — 2 0
0 -. 0 2
3 0 2 2
0 — 0 2
0 -. 0 4
0 0 0 4
3 3 0 0
0 -. .. 6
0 -- 0 4
0 -. 0 6
-. 0 6
3 3 0 0
0 .. 0 0
0 -- 0 0
0 — 0 0
5 -. 0
5 .. .- 0
3 0 0 0
0 3 0 0
0 0 0 0
— .. 5 —
0 3 0 0
0 3 0 2
0 0 0 0
0 .. 5
0 -. 5 0
5 — —
o 0 0 0
-- — 0 0
0 0 0 0
0 -. 0 0
0 — 5
5 — —
0 — 0 0
5 .. 0 0
0 0 0 0
0 -- 0 0
— - . 0 0
3 — 2 0
5 .. .. 0
0 0 0 0
0 — 0 0
0 .. 0 0
0 3 0 2
0 0 0 0
5 — 0 0
0 0 0 0
-- — 2 2
0 0 0 4
3 -- -- 0
3 •. 0 0
1,000
1,000
16,500
100 3,000
4,600
4,500
6,200 6,840
600 122
42,000
1,210
6.400
3,500
5,620
3,800
1470
7,570
700
1,700
27
580
4,320
3.925
1,690
3.000
34
0020
33 800E.06
26 387E-07
18 320E .08
3 600E-06
116
14 1 50E-09
0004 160E-05
31 370E-16
06 140E-15
01 2.OOE .12
24 5 1OE-14
-5
5
5
5
5
0
5
2
2
2
5
5
5
2
2
5
2
5
0
5
5
S
5
S
5
5
S
5
5
5
5
5
7
7
7
7
7
7
7
6
6
6
6
6
6
6
6
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
S
5
S
5
5
5
S
S
5
5
5
5
S
5
S
S
5
5
4
4
3
3
100,000 1.150
75,000
3,200
305
100,000
28
2,000 4.300
89. 100
195
70
8,100 3,000
200,000
312,000
6.150 373
112,000 2,400
10
7,300 8,600
8,900 1,400
170
670
13
-------
TABLE 1. PRIORfl1ZATION OF PESTICIDE ACTIVE INGREDIENTS
Na CAS No. Pollutant Name
217 759944 EPIC
218 8018017 Mancozeb
219 122429 Propham
220 96128 D bromo-3 .ch1oropropane. 1,2-
221 120365 Dichlorprop
222 1399800 Hyamine 2389
223 68424848 Hyamme 3500
224 123331 Maleic hydrazide
225 23950584 Pronamide
226 95067 Sulfallate\CDEC
227 3566107 Aniobam
228 121540 Bcnzethonjwn chloride
229 120514 Benzylbenzoale
230 51026288 Busan40
231 2491385 Busan9O
232 2675776 Otloroneb
233 76062 Cliloropicnn
234 101100 aop
235 14951918 Copper EDTA
236 5825876 CPA
237 54460468 Cycloprate \Z.rdex
238 134623 Dcci
239 957517 Diphenamid
240 91532 EtJtoayqutn
241 502556 EXD
242 85347 Fcnac\Qilorfenac
243 34375284 RAE
244 41206160 1-tPMTS
245 29803574 HP ’FMS
246 13590971 Me*asol DCII
247 53404628 Melasol 326
248 15716026 Methyl benzethionium chloride
249 124583 Methylaraonsc acid
250 136458 MGK 264
251 113484 MGK326
252 138932 Nabonate
253 15339363 Niacide
254 18530568 Norea\Noruron
255 1114712 Pebulale\TiIIam
256 51036 Piperonyl butoxide
257 120627 Piperonyl sulfoxide
258 55406536 Polyphase \ Guardsan 388
259 79094 Propanoic acid
260 134316 Quinohnolsulfaze
261 1982496 Siduron
262 50723804 Sodium bentazon
263 38527900 Sulprofos oxon
264 1940438 Tenachlorophene
265 23564068 Thiophanalc ethyl
266 7779274 Vincide III
267 12122677 Zineb\DithaneZ
268 95501 Dichlorobenzene, 1.2.
269 106467 Dichlorobenzene, 1.4-
270 132661 Naptalam
Fxesh- Human
water Health Oral
Acute W&O LDSO BQ Law
( ugh) (ugh) (mgjkg) (1f g) Constant
11,500 840 2,550 22 200E-05
460 1.720 8,000 6
8.000 510 3,000 56
36,500 170 9 3 11E-04
400 23
1,200 389
447 80
2,340 01 180E .06
5,620 0 10 1 90E-06
850 26 700E-06
5,620 0 0008
125,000 17,500
72,000 2,600
1,150
17,820
1,400
4,800
1215
21,000
720.000
75,000
32.000 1.040
0010
11,000 16 IOOE-04
23 2 .20E-03
603
576
794 003
9,720 003
0020
37
48 1 OOE.04
2,500
1.200
7500 71
Chemical Ranking
Acute W&O Oral BCF IILC TOTAL
0 3 0 0 0 3
3 0 0 0 — 3
0 3 0 0 •. 3
0 -- 2 0 0 2
- . — 2 0 •- 2
0 — 2 — — 2
— .. 2 0 .. 2
0 0 0 0 2 2
0 0 0 0 2 2
0 0 0 2 2
0 — 0 0 — 0
0 -- -. — .. 0
0 — .. — .- 0
— •- — 0 — 0
0 .. .. — •- 0
— 0 0 0 0
5 .. — 0 .5 0
0 •- — .- — 0
0 — .- —
0 — — -.
0 .- 0 0 —
0 0 0 0 —
— 0 — -.
0 .. 0 0 —
— — 0 0 --
0 .. - . 0 —
0 0 0
0 — 0 -- —
0 — 0 0 —
— .- .- 0 -.
0 .. 0 0
0 .. 0 0 0
0 -- 0 — —
— — 0
0 •- 0 0
— — 0
0 .- 0 0
0
0
— - . - . 0
0 •- 0 .- .. 0
0
19
21,000
2,000 19
1.050 3
1,100
31
02
6
900
5,230
3,640
2,000
1.120
7,500
2,000
810,000
1,590
2,600
1,400
7.400
2,820
50,000
18,000
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16,200 10,000
20,800 1,750
1,580 400
1,120 400
76,000
5,200 0001 1 30E .05
56 193E-03
56 2.89E-03
8,200 31 1 90E-03
0 0 0 0 0
0 3 — 0 -5
0 3 — 0 -5
0 •. 0 0 -5
14
0
-2
-2
-5
-------
...-—.
. .
.
0
,
.
Ø/.i/ .
4//

0
/
.

0
/
.0
/
.
7XY7A A i
4
I
Table 2. Top 20 Ranked Pcs kide Active I gr.dienti
No.
CAS No.
Pollutant Name
Overall
Hazard
Score
Use
Types
Use
Restrictions
Aquatic
Hazard
Labeling
1
72208
Endrin
42
INSECFICIDE
YES
NA
2
2104645
EPN San&ox
42
INSECTiCIDE
NO
NA
3
298044
Disulfoton
38
INSECFICIDE
YES
YES
4
298022
Phorate Fainophos\Thiinet
3*
INSECTICIDE
YES
YES
5
298000
Parathion methyl
37
INSECTICIDE
YES
YES
6
8065483
Dcmeeon\Systox
36
INSECFIC IDE
YES
NA
7
55389
Fenthion\Baytex
35
INSECTICIDE
NO
NA
8
57749
Chlordane
34
INSECTICIDE
YES
NA
9
76448
Heptachlor
34
INSECTICIDE
YES
NA
10
56382
Parathion ethyl
33
INSECTICIDE
YES
YES
11
58899
BHC, gamma-\Undane
32
INSECTICIDE
YES
YES
12
70304
Hexachlorophenc
32
FUNGICIDE
NO
NA
13
77*6347
Mevinphoa Phosdrin
32
INSECTICIDE
YES
YES
14
*1812
Warfarin
32
RODENTICIDE
NO
NA
15
563122
Ethion Bladan
30
INSECTICIDE
YES
YES
16
1582098
Tnfluralin\Treflin
30
HERBICIDE
NO
YES
17
86500
Aziophos methyl\Guthion, methyl-
29
INSECTICIDE
YES
YES
18
*001352
Toxaphene
29
INSECTICIDE
YES
NA
19
116063
Aldioarb\Temik
27
INSECTICIDE
YES
YES
20
2921*82
Ch1orpyrifos Dursban
27
INSECTICIDE
NO
YES
• Priority pollutant.
5266cY22 Rq,on\PAI
so
Figure 1. Distthtdioa of Hazard Scores
For 270 Pesticide Adive Ingredients
I0
40
p
a
I
3
I
N
C
y
$3
30
10
0
40—46 11—40 11—11 56—60 11—11 I— 50 IL—IS S—IS
3C001 cm.i.a
1-4 —4—4 —4
15
-------
TABLE 3. PESTICIDE ACTIVE INGREDIENTS RECOMMENDED FOR FURTHER TESTING AND RESEARCH
N CAS No. Pollutant Name
1 58366 Phenoxar!Ine, 10.IO’.oxydi-
2 81990336 KN Methyl
3 62748 Sodium fluoroacetate
4 3691358 Oilorophacinoee
5 51350848 BBTAC
6 141662 Dicrotophos\Bidnn
7 15504.4 Vencidc5lZ\Zetax
8 4080313 Dowicil75
9 26530200 Ocduhnone
10 21564170 Busan72
11 128030 llusan85
12 117522 Coumafuryl
13 52857 F inpbur\Famophm
14 7166190 Giv.gard
15 112561 Letliane 384
16 569642 Malachite gram
17 6317186 NalcoD-2303
18 83261 Pindone
19 31512740 Busan77\PB )
20 120365 Dichlorpmp
21 1399800 Hyamme 2389
22 68424848 Hyamme 3500
23 121540 Benzethoniuzn thionde
24 120514 Benzylbenzoate
25 51026288 Busan40
26 2491385 Husan90
27 101100 Cloprop
28 14951918 CopperEDTA
29 5825876 CPA
30 54460468 Cycloprate\Zardex
31 91532 Edioxyqwn
32 502556 EXD
33 34375284 MAE
34 41206160 HPtvfl’S
35 29803574 HPTMS
36 13590971 Metatol DGH
37 53404628 Metasol J26
38 15716026 Methyl beazethionium chlonde
39 136458 MGK264
40 138932 Nabonate
41 15339363 Niacide
42 51036 Piperonyl butoxide
43 120627 Ptpcrony l sulfoxide
44 55406536 Polyphase\Guardsan 388
45 134316 Qumolmolsulfaxe
46 50723804 Sodium battazon
47 38527900 Sulprofosoxon
48 1940438 Teuachlorophene
49 23564068 Thiophanate ethyl
50 7779274 Vancide Th
10 -- 5 -- -- 15
12 0 .- 12
— 12 0 — 12
— 10 .. .. 10
8 — 8
3 — 5 -- — 8
— •. — 8 — 8
0 — — 6 .. 6
-- — 0 6 — 6
5 .. 0 .. — S
5 — -- 0 — 5
— .. 5 .. — 5
0 — 5 — .. 5
5 — .. .. .. 5
O -- 5 — — 5
5 .. -. .. .- 5
5 — .- 0 — 5
— — 2 2 — 4
3 . — Q .. 3
— — 2 0 2
O -. 2 .. — 2
-- -- 2 0 -- 2
0 .. .. .. .. 0
0 — -- -- -- 0
-- -. -. 0 — 0
0 -- -- -- — 0
O -. -- — -- 0
-- — — — — 0
0 — -- — 0
0 -- -. — 0
— — — -- — 0
603 — — 0 — — 0
— -. -- .. — 0
-. — .. — — 0
-. -- .- — — 0
— — -. -- -- 0
5.230 0 — 0 — .. 0
— — — -- 0
-. — -. 0 — 0
0 -. 0 -- -- 0
-- 0 -. -- 0
-- — .- -- — 0
-- -- 0 — — 0
-- .. - - -. — 0
— -. -. — .- 0
-- -. .- .. 0
10,000 0 -- 0 — 0
-. — .- — 0
Fresh-
Human
water
Health
Oral
Hcnzy’i
Acute
(ugh)
W&O
(ugh)
LD5O
(mg/kg)
BCF
(1/kg)
Law Chemical Ranthg
Constant Acute W&O Oral BC? HLC TOTAL
o 004
05
151.400
41,700
L300
280
0020
24
O 129
0 066
106
128
1,470
1,590
1470
27
34
3
280 121
0 240
400 23
389
447 80
0010
180
430
42,000
36
60
4,850
20
2,200
305
70
170
1,200
1.400
4,800
1,215
21,000
21,000
720,000
9,720
1,590
2,820
16,200
794 003
003
-. 0 0 — 0
0 -. — 0 — 0
0 020
7 ,500
2,000
1,200
16
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