x>EPA
United Stettt
Environmental Prottctlon
Agmcy
OfflMOf
PwticidM and Toxic Substanca*
Washington DC 20460
EPA RS-85-027
September 1985
PMticktai
Guidance for the
Reregistration of
Pesticide Products
Containing LJndane
as the Active Ingredient
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GUIDANCE FOR THE
REREGISTRATION OF PESTICIDE PRODUCTS
CONTAINING
AS THE ACTIVE INGREDIENT
LINDANE
Case No. 0315
ENVIRONMENTAL PROTECTION AGENCY
OFFICE OF PESTICIDE PROGRAMS
WASHINGTON, D.C. 20460
September 30, 1985
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APPENDICES
Page
11—1 Guide to Bibliography . . . . . . . . . . . . . . . . 253
11—2 Bibliography . . . . . . . . . . . . . . . . . . . . 255
11—3 FIFRA S3(c)(2)(B) Summary Sheet — EPA Form 8580—1 . . 262
11—4 Certification of Attempt to Enter Into an Agreement
with Other Registrants for Development of Data —
EPA Form 8580—2 . . . . . . . . . . . . . . . . 263
11—5 Formulator’s Exemption Statement . . . . . . . . . . 264
111—1 Product Specific Data Report (End—Use Products) . . . 265
iv—1 40 CFR 162.10 Labeling Requirements . . . . . . . . . 267
IV—2 Table of Labeling Requirements . . . . . . . . . . . 271
IV—3 Physical/Chemical Hazards Labeling Statement . . . 277
IV—4 Storage and Disposal Instructions . . . . . . . . . . 278
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TABLE OF CONTENTS
Page
I. Introduction . . . . . . . . . . . . . . . . . . . . . , 1
II. RegulatoryAssesSmeflt . . . . . . . . . . . . . . . . . 4
A • I n t rod uc t i On • . . . • . . . . . • . . . • . • . • 4
B. Chemical Description and Use Profile . . . . • • • 4
C. Regulatory Position and Rationale . • • • • • • • . 6
D. Criteria for Registration under the Standard . . . . 25
E. Acceptable Ranges and Limits . . . . • • . • . . . . 25
F. Required Labeling • . . • • • . . . . • . • . • . • 26
G. Tolerance Reassessment . . . . . • . . . • • • • • • 34
III. Requirement for Submission of Generic Data . • . . . • • 175
IV. Requirement for Submission of Product—Specific Data • • 238
V. Submission of Revised Labeling • • • • • • . . . . . . • 242
A. Label Contents • . • • . . . . . • . . • • • • . • . 242
B. Collateral Labeling . . . . . . . . • . . . • . . • 248
VI. Instructions for Submission. . . . . • . . . . . . . . . 249
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I. INTRODUCTION
The Federal Insecticide, Fungicide, and Rodenticide Act
(FIFRA sec. 3(g)) directs EPA to reregister all pesticides as
expeditiously as possible.
To carry out this task, EPA has established the Regis-
tration Standards program, which will review all pesticide
products containing active ingredients first registered before
January 1, 1977. pesticides generally will be reviewed in
use clusters which have been ranked to give earliest review
to pesticides used on food and teed crops.
The Registration standards program involves a thorough
review of the scientific data base underlying pesticide
registrations and an identification of essential but missing
studies which may not have been required when the product
was initially registered or studies that are now considered
insufficient. EPA’S reassessment results in the development
of a regulatory position, contained in a Registration Standard,
on each pesticide and its uses. The Agency may require the
registrant to provide additional data to support existing
registrations, modify product labels to provide additional
precautionary statements, restrict the use of the pesticide
to certified applicators, provide reentry intervals, modify
uses or formulation types, specify certain packaging limita-
tions, or other requirements to assure that proper use of the
pesticide will not result in adverse effects on the environ-
ment. The Registration Standard may lead to initiation ot
a Special Review it it appears that use of the product may
cause unreasonaible adverse effects on the environment. The
Special Review can result in a decision by the Agency to seek
a change in the conditions of registration, suspension, or
cancellation of the registration.
The scientific review, which is not Contained in this
Guidance Document but is available upon request, focuses on
the technical grade of the active ingredient and identities
missing generic data. However, during the review of these
data we are also looking for potential hazards that may be
associated with the end—use (formulated) products that contain
the active ingredient. If we have serious concerns, we will
address end—use products as part of the Registration Standards
program and will propose regulatory actions to the extent neces-
sary to protect the public.
EPA has the authority under FIFRA sec. 3(c)(2)(B) to
require registrants to submit data regarding the hazards which
may result from the intended use of a pesticide. Although
sec. 3(c)(2)(B) provides that all registrants are responsible
for these data, the Agency generally imposes generic data
:1.
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requirements only on the registrants of the manufacturing_use
products (basic suppliers of the active ingredient) and other
producers who do not qualify for the formulator’s exemptjon.*
A producer who does not currently qualify, but wishes to
qualify for the formulator’s exemption, may change his source
of supply to a registered Source, provided the source does not
share ownership in common with the registrant’s firm. A regis-
trant may do so by submitting a new Confidential Statement of
Formula (EPA Form 8570—4), identifying the registered source
of the active ingredient, to the appropriate Product Manager
within 90 days of receipt of this Guidance Document. The
chart on the following page Shows what is generally required
of those who do and who do not qualify for the formulator’s
exemption in the Registration Standards program,
If you decide to request the Agency to cancel the regis-
tration of any of your products subject to the requiremen
of this Guidance Document, please notify the Product Manager
named in the cover letter, within 90 days from the receipt
of this document. If you decide to maintain your product
registration(s), you must provide the information described in
the following pages within the time frames Outlined. EPA may
issue a notice of intent to cancel or suspend the registratj 0
of any currently registered product which does not Comply
with the requirements set torth in this Guidance Document.
you are reminded that FIFRA sec. 6(a)(2) requires you to
submit factual information raising concerns ot possible
unreasonable adverse effects of a pesticide. You should
notify the Agency ot interim results of Studies in progress
it those results show possible adverse effects.
*The formulator’s exemption applies to a registrant of an
product if the source of his active ingredient(s). (1) is a
registered product and (2) is purchased from a source which
does not have ownership in common with the registra . 8
f i rm.
2
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PRODUCTS SUBJECT TO THE ACTION(S) REQUIRED TO
REGISTRATION STANDARDS PROGRAM MAINTAIN REGISTRATION
I. products That Do Not ualify
For The Formulator’s Exemption
A. single Active Ingredient These products must be reregis—
Products* tered. To obtain reregistration,
labeling, packaging, and data
requirements must be satisfied
in accordance with the Regis-
tration Standard’s Guidance
Document.
.......................•s••••••••• .......S...................S......
B. Multiple Active Ingredient These products will not be
products reregistered at this time.
However, generic data required
to continue the registration ot
the active ingredient under
review, as described in the
Registration Standard’s Guidance
Document, will be required and
some labeling precautions may
also be required.
ii. products That Do Quality FO only when additional restric—
The Formulator’s Exemption tions or labeling are needed to
protect man or the environment
will these products be sub3ect
to the Registration standard
requirements. Affected products
will be dealt with in a variety
of ways, including but not
limited to the Label Improvement
program and special intent
to cancel notices.
* End-use products of registrants who also produce a manutacturiflg
use product will not be required to be reregistered provided that
registrant fulfillS the requirements specified in the Guidance
Document for product(s). Such end—use products
will be subject to the labeling changes required for products in “II”
above, It there are no manufaCtUrifl9 se products registered by any
Company, end-use products will be required to be reregistered.
NOTE: It all registrants in “i” above tail to meet the requirements
in “I—A” and “I—B” above, then the registrants mr “II” Lose their
right to quality for the formulator’s exemption and become subject
to the requirements in “I—A” and “I-B”.
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II. REGULATORY ASSESSMENT
A. INTRODUCTION
This chapter contains the Agency’s regulatory position on
products containing the pesticide lindane as the sole active
ingredient. The Agency bases its position and rationale on a
consideration ot all uses of lindane appearing on pesticide
products registered under Sections 3 and 24(c) of FIFRA as
well as on products authorized for distribution in intrastate
commerce under 40 CFR 162.17. The Agency has reviewed the
known chemical, environmental, and toxicological characteristics
of this pesticide and its established tolerances for residues
in or on food or teed commodities. i rom these considerations,
the Agency sets forth the data and labeling requirements that
must be met by registrants and applicants for registration of
lindane products in order for their products to be registered
or reregistered under this Standard. unique labeling require-
ments and certain data needs for end—use products (EPs) that
contain lindane are also established by this Standard.
Only those data and labeling requirements for current
and future substantially similar MPs and EPs are addressed
here. Future products that differ appreciably from those
described in this Standard may be subject to additional data
and/or labeling requirements.
B. Chemical Description and Use Prof ile
Lindane is the common name accepted by the International
Organization for Standardization for the insecticide consisting
of > 99% of the gamma isomer of l,2,3,4,5,6—hexachlorocyclohexane.
In Great Britain the compound is known as Gamma HCH or Gamma SHC.
The Chemical Abstract name is l , 2 , 3 , 4 a , 5 a, 6 —hexachloro—
cyclohexane. Lindane is marketed under the trade names Exagamma,
Forlin, Gallogamma, Gammaphex, Gaininex, Gexane, Grammapoz, Gram-
mexane, Inexit, Kwell, Lindator, Lindagrain, Lindagram, Linda—
granox, Lindalo, Lindamul, Lindapoudre, Lindaterra, Lindex,
Lindust, Lintox, Novigram, and Silvanol. The Empirical Formula
is C 6 H 5 C1 6 and the molecular weight is 290.0. The Chemical
Abstracts Service (CAS) Registry Number is 58—89—9 and the EPA
Chemical Code Number is 009001.
Technical lindane is not manufactured in the United States.
All of the technical lindane used in this country is imported
from France, Germany, Spain, Japan, and China.
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Benzerle hexachioride (BHC) contains a mixture of alpha,
beta, and gamma isomers. Lindane is the qamina isomer of BHC.
BHC was once used as an insecticide and earlier data were
generated using the mixture of the isomers. Shortly after the
initiation of the Agency’s Rebuttable presumption Against
Registration (RPAR) review of lindane in 1977, EPA required
registrants of BHC to reformulate their technical products to
exclude the alpha and beta isomers of BHC, which had been found
to be generally more toxic than the gamma isomer. Lindafle
should not be confused with hexachlorObeflZene, which is a
fungicide with its own pesticidal uses and data base.
Technical lindane is a white crystalline solid with a
melting point of 112°C. It is stable to light, heat, air and
strong acids but decomposes to trichlorObeflZefles and HC1 in
alkali. It is soluble in most organic solvents and is soluble
in water at 10 parts per million (ppm) at 20°C. Other chemical
and physical properties include vapor pressure of 9.4 x 10-6
mm Hg at 20°C, and specific gravity 1.85. Existing data gaps
relating to product chemistry are identified in Table A and
Table B.
There are 25 anufactUriflg-USe products, 183 Federally
registered FIFRA Section 3 end—use products and 81 FIFRA
Section 24(c) Special Local Need registrations containing
lindane as the sole active ingredient. products containing
lindane in combination with another active ingredient (other
than solvents) include 94 Federally registered FIFRA Section 3
end—use products and 5 FIFRA Section 24(c) special Local Need
registrations. All intrastate products were removed from
commerce effective October 1, 1984 by the Notice of Intent
to Cancel pesticide products containing Lindane (48 FR 48512,
October 19, 1983).
Lirkdafle is formulated into emulsifiable concentrates,
flowable concentrates, soluble concentrate/liquids, wettable
powders, dusts, wettable powder/dusts, ready—to-use liquids,
pressurized liquids, and impregnated materials.
Lindane is an insectiCide/aCaracide registered for use
on a variety of fruit and vegetable crops (including seed
treatment), ornamentals, tobacco, greenhouse vegetables and
ornamentals, forestry (including Christmas tree plantations),
domestic outdoor and indoor uses by homeowners (including dog
dips, household sprays and shelf paper), commercial food or
feed storage areas and containers, farm animal premises, wood
or wooden structure sites, and human skin/clothing (military
use only).
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Aerial application of lindane is prohibited. Lindane
may be applied as a dip tank solution (livestock, lumber, and
pets), as a livestock spray, by ground equipment delivering
a ground or foliar spray or dust, by soil incorporation, by
soil injection in combination with a fumigant (for the pine-
apple use only), as a smoke (for greenhouse fumigation only),
and as a dust to human skin/clothing (military use only).
C. REGULATORY POSITION AND RATIONALE
The regulatory history of lindane includes a full EPA
Rebuttable Presumption Against Registration (RPAR) review
based on questions of oncogenicity, fetotoxicity/terato—
genicity, reproductive effects, its potential to cause
blood dyscrasias, and acute toxicity to aquatic wildlife.
Position Documents were published in 1977 (PD—i), in 1980
(PD—2/3) and in 1983 (PD—4). A Notice of Intent to Cancel
Pesticide Products Containing Lindane was issued October 19,
1983 (48 FR 48512, October 19, 1983). The triggers for
fetotoxicity/teratogenicity and reproductive effects were
successfully rebutted. Its potential to cause blood dyscra—
sias could not be confirmed with the data on hand. The trigger
for acute toxicity to aquatic wildlife was withdrawn because
lindane is no longer registered for uses involving direct
aquatic application.
The oncogenic effect was not rebutted. As a result of
a risk/benefit analysis based on the oncogenic risks, the
RPAR decision resulted in the phasing out of registrations
for lindane smoke fumigation devices for indoor domestic
use (with cancellation becoming effective May, 1986) and in
the cancellation of lindane dog dips for the control of pests
other than mites. The dog dip cancellation was challengea,
and subsequently the dog dip use for pests other than mites
was permitted for veterinary use provided additional precau-
tions to limit applicator exposure appeared on the labeling.
The Notice of Intent to Cancel Pesticide Products containing
Lindane (48 FR 48512, October 19, 1983) also restricted
certain uses of lindane to Certified Applicators or persons
under their direct supervision. The restricted uses include
avocados, pecans, livestock sprays, forestry, Christmas trees,
commercial ornamentals, structural treatment, dog shampoos,
and dog dusts. The Notice of Intent to Cancel also required
the use of protective clothing for applicators using lindane
products for seed treatment by manual means, livestock sprays,
avocados, pecans, forestry, Christmas trees, hardwood lumber,
ornamentals, crawl space treatments, dog dips, and dog shampoos.
This Registration Standard reflects a reassessment of the
data base used in the RPAR review for lindane, as well as all
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other data available to the Agency, and specifies additional
studies which have been determined, based on this review, to
be required to support the registration(s) of lindane. The
PD—4 provides further discussion of many of these issues.
Based on a comprehensive review and evaluation of all
available data and other relevant information on lindane,
the Agency has determined the following:
1. Manufacturing—use pesticide products that contain
lindane as a sole active ingredient may be registered for
sale, distribution, reformulation, and use, subject to the
terms and conditions specified in this Standard and current
label requirements. Registrants must provide or agree to
develop additional data, as specified in Tables A and B, in
order to maintain existing registrations or to permit new
lindane registrations.
Rationale : Except for the forestry and uninhabited
buildings and empty storage bins spray uses, as described
elsewhere in this chapter, the Agency has concluded based on
available data that, for all other currently registered uses,
the benefits of lindane exceed the risks, so long as the
precautions required by this Standard are adhered to. Even
though the review indicates that certain studies are needed
by the Agency, under FIFR.A the Agency may choose not to
cancel or withhold registration it data are missing or are
inadequate (see Sections 3(c)(2)(B) and 3(c)(7) of FIFRA).
Rather, issuance of this Standard provides a mechanism for
identifying additional data needs. These data will be re-
viewed and evaluated, and the Agency will determine at that
time whether they will affect the risk/benefit determinations
described in this assessment.
2. The No Observed Effect Level (NOEL), the highest
dose of a test substance that can be administered without
eliciting any signs or other toxic reactions in test animals,
has been lowered for systemic effects of lindane since the
issuance of PD-4 based upon recent Agency acceptance of a
subchronic feeding study in rats. Until the results of an
acceptable chronic feeding study are submitted and evaluated,
the Agency will use the subchronic study to establish a
provisional Acceptable Daily Intake (PADI), which represents
the Agency’s determination of an acceptable level of dietary
exposure to residues of a pesticide per kilogram of body
weight. The Agency is requiring the submission of a chronic
feeding study in rats so that an Acceptable Daily Intake (ADI)
can be determined.
Rationale : The available rat chronic studies do not meet
current Agency Guideline criteria (Pesticide Assessment Guide-
lines, Subdivision F, Hazard Evaluation: Human and Domestic
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Animals; November 1982). Therefore, the Agency is requiring
the submission of an adequate rat chronic feeding study so
that an ADI can be determined based upon the experimentally
determined NOEL. The ADI (which traditionally is based upon an
adequate chronic toxicity Study) or PADI, which is an interim
level based upon the NOEL from any other valid toxicity study)
is calculated by dividing the NOEL by an appropriate safety
factor. The Agency uses a safety factor of 1000 to calculate
the PADI when the NOEL is based upon a subchronic study. For
the present time, the best available source for determining a
PADI is the subchronic 90—day feeding study in the rat, which
was received shortly before the lindane RPAR was completed.
This study, which meets current Guideline criteria (cited
above), shows that lindane causes toxicity related changes,
primarily in the kidneys but also in the liver, of male and
female rats. Renal changes, which included tubular degenera-
tion, hyaline droplets, tubular casts, tubular distention,
interstitial nephritis, and basophilic tubules, were irrevers-
ible with a NOEL of 4 ppm in the diet which is equivalent to
0.3 milligrams per kilogram of body weight per day (mg/kg/day).
Hypertrophy was the only dose—related liver change noted.
Using the 0.3 mg/kg/day NOEL and a safety factor of 1,000,
the PADI for lindane has been determined to be 0.0003 mg/kg/day.
When the results of an acceptable rat chronic study are available,
the Agency can determine an ADI for lindane.
3. Although the Agency is unable to complete a tolerance
reassessment because of certain residue chemistry and toxicol-
ogy data gaps, the Agency concludes that no changes in present
tolerances are indicated at this time. However, the Agency is
requiring submission of data regarding residues resulting from
seed treatment uses and, based on review of those data, may
require tolerances for those uses to be established. Because
of the Agency’s concerns about the possibility of human health
effects due to dietary exposure to lindane and the lack of data
to support current tolerances, no additional tolerances, other
than those required to support the existing seed treatment uses,
will be considered until the data gaps identified in this
Standard are filled.
Rationale : As noted in item 2 above, the NOEL for lindane
has been lowered since the issuance of PD—4 based upon receipt
of the subchronic feeding study in rats. The NOEL determined
from this study is 0.3 mg/kg/day. Using this value and a
safety factor of 1,000, a PADI for lindane of 0.0003 mg/kg/day
has been calculated. The Maximum Permissible Intake (MPI), or
maximum allowable daily dietary intake of residues for a given
pesticide which, based upon laboratory animal studies, should
not produce any adverse effects, is calculated by multiplying
the ADI or PADI times the body weight of the individual. For
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a 60 kilogram (132 pound) person, the MPI of lindane is 0.018
mg/day. The percentage of the MPI used by the Theoretical Max-
imum Residue Concentration (TMRC), which is derived from the
sum of all existing tolerance values, is 7,883%. Exceeding
the MPI with the TMRC does not in and of itself necessarily
represent an immediate public health hazard. The actual residue
levels of lindane to which the public is exposed are likely to
be significantly less than indicated by the TMRC for reasons
which include the following: a) the Food and Drug Administration
(FDA) market basket surveys indicate that the actual residues
of lindane are far below the established tolerances and that
less than one percent (0.7%) of the MPI is actually used;
b) not every individual crop for which a tolerance has been
established is treated with lindane; c) not every crop that
actually is treated with lindane is treated at the maximum
allowable rate or with the minimum pre—harvest interval;
d) not all livestock animals to which this pesticide may be
applied are actually treated with lindane; e) washing or
peeling food for consumption would reduce residue levels;
and f) not all the crops contributing to the MPI are likely
to be consumed by an individual.
No tolerances exist for the seed treatment uses of lindane
because they were not required at the time these uses were
registered by USDA. USDA had concluded, based upon the analyt-
ical methodology available at that time, that no residues were
or would be present in plants as a result of seed treatment by
any pesticide. Thus, all seed treatments were considered to be
non—food uses. EPA now considers that tolerances should be
established for all seed treatment uses unless it can be shown
by data from a radiolabeled chemical study that no uptake of
residues occurs from the treated seeds into the aerial or
edible portion of the growing crop.
EPA will reassess existing tolerances after review of the
required residue data, including identification of metabolites
in plants and livestock and determination of the residue levels,
if any, that may be present in the edible portion of food crops
as a result of seed treatment, and will establish an ADI after
review of the required rat chronic feeding study. Until these
studies are evaluated and an ADI set, no additional tolerances
for lindane will be considered, other than those required to
support the existing seed treatment uses.
4. As a result of the RPAR process, the Agency concluded
that the genotoxic potential of lindane could not be determined
from available data. Therefore, the Notice of Intent to Cancel
pesticide Products Containing Lindafle (48 FR 48512, october 19,
1983) required the submission of additional studies. The con-
sortium ot lindane producers, Centre International d’Etudes du
Lindane (dEL), agreed to perform special mutagenicity tests
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for lindane which would optimize conditions for activation of
this chemical and would provide especially sensitive conditions
for detecting mutagenic endpoints so that an assessment of its
genotoxic potential could be made. The Agency has completed
its review of these studies. Based upon evaluation of all
available mutagenicity data on lindane, including the new
studies, the Agency has concluded that lindane does not appear
to produce mutagenic effects. No further mutagenicity studies
are required.
Rationale : The recent mutagenicity tests submitted by
CIEL appear to confirm that lindane has little or no genetic
activity, even when subjected to sensitive tests for detecting
DNA events with special provisions for activation. Lindane
was negative in the Ames test in the presence of a microsomal
metabolic activation system (s—9) from the tumor-susceptible
CF—i mouse strain. Metabolic systems for Ames testing were
manipulated so as to enhance the possibility ot activation of
lindane and improve the availability of its active metabolites.
Lindane was also negative in mammalian assays for gene muta-
tion and for Sister Chromatid exchanges in CF—i mice by the
oral and parenteral (intraperitoneal) routes.
5. Since the issuance of PD—4, the Agency has published
Proposed Guidelines for Carcinogen Risk Assessment (49 FR 47294,
November 23, 1984). The Carcinogen Assessment Group (CAG) of
the Office of Research and Development CORD) of the EPA has
reassessed the oncogenic potential of lindane using these new
guidelines and the results of the new mutagenicity tests that
show lindane is not genotoxic. Based on the weight of evidence,
CAG has classified lindane in the range B2-C. Pending receipt
of the required rat oncogenicity Study, the Agency will regulate
lindarie as a class C carcinogen.
Rationale: CAG was requested to review the weight of
evide F arcjnogenjcjty of lindane given the results of
the new mutagenicity testing. using the new Proposed Guid.—
lines for Carcinogen Risk Assessment (cited above), CAG has
classified lindane as “B2-C” (i.e., in between the lower half
of the “B” category of “probable” and the “C” category of
“possible” carcinogen classifications) based upon evidence
that lindane gives rise to malignant liver tumors in two
strains of mice, plus supportive evidence of pre-cancerous
liver lesions in shorter ternt studies. This weight of evidence
classification also included consideration that, on the one
hand, 1) at least one study was positive in both sexes and that
2) a lindane metabolite is oncogeriic, while, on the other hand,
and leaning the classification toward class “C”, that 3) lindane
has not been shown to be genotoxic after extensive testing,
and 4) none of the oncogenicity studies showed a dose—response
relationship. OPP believes that the weight of evidence is
closer to a “C” class than to a “B2” class carcinogen. This
will be reassessed based on the results of the required rat
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oncogenicity study (see item 6 below). Therefore, pending
the results of this study, OPP will regulate lindane as a
class C carcinogen.
6. The Agency has determined that its daia base on pos-
sible oncogenic effects of liridane is not complete. While
lindane has been determined to be associated with increased
incidences of liver tumors in at least two studies using mice,
the Agency does not have a comparable acceptable study conducted
with rats. The Agency requires submission of an additional.
rat oncogenicity study but does not require submission of an
additional mouse bioassay.
Rationale : The Agency has reviewed the data base for onco—
genicity in the rat. The available data do not meet current
acceptability criteria or permit definitive decisions on the
oncogenic potential of lindane in the rat. Therefore, the Agency
is requiring that a rat oncogenicity bioassay be performed.
Since the previous mouse bioassays, although individually not
meeting the current Guideline criteria (pesticide Assessment
Guidelines, Subdivision F, Hazard Evaluation: Human and Domestic
Animals; November 1982), when considered together indicate the
oncogenic nature ot lindane in mice, CAG was asked to consider
whether another mouse bioassay of lindane, meeting current
Guideline requirements, was needed. CAG indicated that while
another mouse study might improve the basis of the quantitative
risk assessment, it would not change the conclusion that lindane
causes cancer in mice. The Agency does not believe that an
additional mouse study would refine the quantitative risk assess-
ment enough to justify the additional cost of •doing another
study, because of the inherent uncertainty associated with
low—dose extrapolations for humans from mouse liver tumors.
7. Lindane has been associated with possible induction
of aplastic anemia (a more specific term for blood dyscrasias).
The Agency is requiring a laboratory animal study to determine
if a cause and effect relationship exists between exposure to
lindarie and the formation of blood dyscrasias.
Rationale : PD—4 of the ]indane RPAR concluded that the
available epidemiological data did not permit a cause and
effect relationship to be established betweeen lindane and
aplastic anemia. The possibility that lindane may induce
aplastic anemia in.certain susceptible humans still exists.
Therefore, the Agency is requiring submission of a laboratory.
animal study to permit an assessment of lindane’s potential to
cause blood dyscrasias. Registrants must contact the AgenCy
within 90 days of receiving this Guidance Document to discuss
the study, and then must submit a proposed protocol, together
with a projected schedule, for Agency approval prior to
actually conducting the testing.
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8. The Agency has recalculated the exposure to applicators,
Margins of Safety (Mos) relative to toxic effects, and estimates
of the 95% upper confidence level for excess cancer risk for the
various registered uses of lindane. While the new calculations
for most uses do not indicate any significant changes that would
warrant additional regulatory action at this time, the Agency
is concerned about the potential risks to applicators and mixer/
loaders for the forestry use and to applicators spraying uninhab-
ited buildings and empty storage bins. Based on its reassessment
of exposures to these workers, the Agency has decided to commence
Special Review for those use patterns. The uses will continue
to be registered during the period of Special Review, provided
protective Clothing is worn by applicators and mixer/loaders.
The protective clothing requirements for the forestry use as
detailed in the Final Notice of Determination of the lindane
RPAR will continue. Protective clothing requireme , including
use of an approved respirator, must be added to those end—use
products with directions for use in uninhabited buildjngs
and/or empty storage bins.
Rationale : The Agency has reassessed the exposures to
applicators for the use patterns detailed in PD—4 using current
methodology, surrogate studies, and the lower NOEL from the sub—
chronic rat feeding study for those use patterns of a Subchronjc
nature, such as the 30 days of exposure per year associated with
the forestry use. The estimates of the upper 95% confidence
level for excess cancer risk are based on CAGSS recalculation
of the potency (Ql*) of lindane. The new Q 1 * value used in
calculating cancer risk is 1.1 (mg/kg/ day)1, a very small
change from the old 0 * of 1.3 (mg/kg/c ayyl, In addit1 0 ,
the Agency has now calculated the exposures for mixer/loader
or combined mixer/loader/applicator for three uses where this
practice is customary, which includes the forestry use. Expo-
sure calculations for these workers were not included in PD—4.
Current calculations for dermal and respiratory exposures,
together with a comparison of PD—4 and current MOS values and
cancer risk estimates, are presented in Table 1. Based UpOn the
low MOS (the ratio of the NOEL to exposure) that is associated
with the forestry use, both to applicators and mixer/loaders
(especially those servicing more than one applicator), and to
applicators Spraying uninhabited buildings and empty storage
bins, the Agency has decided to commence Special Review for
these uses. The Agency finds that continued registra j 0 of
these uses during the time necessary to complete a Special
Review will not cause unreasonable adverse effects on man or
the environment, provided that protective Clothing require 5
are stipulated On labeling in order to reduce exposure in the
interim. The protective Clothing requireme 5 for the forestry
use, detailed in the Final Notice of Determination of the lindane
RPAR, will Continue. Protective Clothing require 5
use of an MSHA/OSHA approved respirator, must be added to those
end—use products with directions for Spraying uninhabited
buildings and/or empty storage
12
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Table 1
Exposures and Risk Factors Associated with Lindane Uses
Based on Current Exposure Calculations arid lbxicology Data
Nuig,er Daily Exposure (mg/kg)
of days with protective clothing Margin of Safety’! Cancer Risk 2 !
exposed required by current labels
per year Dev1n 1 spiratory Current PD-4 Current P0-4
ornai nta1s 4 0.13 8.6x1(r 4 400* 280 8x1(r 5 lx lO 4
(c zuui!rcial)
avocaios 2 0.27 2.3x1(r 3 200* 99 8x 1 0 5 x1(r 4
pecans:
applicator 1 0.57 Negligible 90* 99 8x lcrS 7x10 5
mixer/ loaier 1 0.46 Negligible 110* 7x1(r 5
cathined 1 1.0 Negligible 50* 1x10 4
livestod 1 0.11 1.5x10 4 450* 448 2x1 r 5 2xlir 5
orna nta1s 1 5.4x 10 2 5x10 4 5,000* 3,846 8x10 6 2x lcr 6
(ha ers)
forestry:
applicator 30 0.10 1.8x10 3 25 1,767 4xi0 4 1x10 4
mixer/loader3/ 30 0.15-0.93/ Negligible 3—203/ 4x10 3 —7x10 4 3!
cait ined 30 0.25 1.8x11r 3 11 1x10 3
]Onas trees—foliar 1 6.8x10 2 1.2x10 3 700* 500 1x 10 5 1x10 5
seed trea nt:
applicator 2 9.3x1(r 3 8 .6xl(r 5 5,000* 5,000 3x10 6 3x10 6
seed sowing 2 1.7xl O 3 3,000* 2,941 sxiir6 5x 10 6
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Nui er r ily Exposure (nvj/kg)
of days with protective clothing Margin of Safety 1 ! Cancer Risk 2 !
exposed required by current labels
per year Derma Respiratory Current PD—4 Current
dog dust:
applicator 2 4x1(r 3 3x 10 5 1,200* 11,628 1x10 6 1x1 r 6
residents 6 8.6x 1(r 5 60,000* 52,140 4xi(r 7 4x10
cucurbits
applicator 3 2.4x10 2 8.6x1(r 6 2,000* 28,736 1110 2xi(r 7
mixer/loader 3 6.6x1(r2 Negligible 150* 1x10 4
cciit,ined 3 7.1x10 2 8.6x10 6 140*
s trees(stunp— 1 0.14 2.2x10 3 360* 256 2x10 5 3x 10 5
slash)
pineapples 1 9.7x10 8 500,000* 1,000,000 2xi0 0 2x10 10
flea collars 4 ! 365 1.6x1(r 6 35,000 145,349 4x10 6 7. 1O—6
shelf paper 365 1.2x](r 5 25,000 725,000 1xl0 5 2.1x10 6
ha sprays:
applicator 1 9x1 0 4 6.3x10 4 7,000* 1,520 2x10 6 4.4x10 6
residents 3 8.6x 1(r 5 60,000* 55,556 4xi0 7 4.2x10 7
hard od logs 200 1.3x10 3 230 962 4xi0 3.6x1(r 4
dog dips: 5 !
applicator 12 l.2x1(r 3 2,500* 71,667 2xiCr 6 4.2x1(r 6
residents 3 8.6xl(r 60,000* 58,140 N/A 6 ! 4.2x10 7
dog shanpoos:
applicator 1 1,700* 1,562 5x10 6 4.5x1(r 6
residents 3 8.6x10 5 60,000* 58,140 N/A 6 / 4.2x10 7
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Table 1 (caitirued)
Nunber imily Exposure (n* Jkg)
of days with protective clothing Margin of safety 1 / Cancer I isk2 /
exposed required by current labels
per year Dermal Respiratory Current 10-4 Current PD-4
crawl space sprays:
applicator S 1.5x10 3 7.7x10 4 20,000* 5,435 7x 10 6 7x106
residents 30 6.9x1 r 4 430 7,246 6x11r 6 6xlcr 6
n th sprays:
applicator / 26 1.8x10 3 2.6xl0 5 1,500 37,425 3x10 5 5x10 5
app1icato r / 26 (3.6x10 4 ) (2.6x10 5 ) (5,000) (1xl0 5 )
nployees 225 3x10 4 1,000 55,556 lxl(r 4 3x1Cr 5
uninhabited buildings
& npty stor e bin :
applicator 9 ” 12 0.17 7x10 4 20 121,957 3x10 4 6.4x10 7
applicator 0 / 12 (3.4xl0 2 ) (7x1Cr 4 ) (75) (7x1(r 5 )
applicatOr lV 12 (3.4x10 2 ) (7x1Cr 5 ) (90) (6x1(r 5 )
1/ Margin of Safety ( los) is the ratio of No Ctserved Effect Level (NOEL) to Exposure, i . e. , NOEL/Exposure.
The current lo8 value is associated with the subchroniC NOEL of 0.3 i /kg unless the value is followed by
an asterisk. The asterisk indicates that the exposure is acute (only a few days per year) and the !‘tJS is
associated with the maternal/fetOtOXiC NOEL of 5 mg/kg, as in PD—4.
2/ Estimate of the upper 95% confidence level for excess cancer risk.
3/ lOiS of 20 and a cancer risk of 7x10 4 if the mixer/loader is servicing only one applicator;
lo)S of 3 and a cancer risk of 4x10 3 if the mixer/loader is servicing six applicators.
4/ The runber of days exposed per year and the cancer risk tar dog dip applications have been adjusted fran that
in PD-4 to conform with the new labeling restrictions. “1 sidentS” refers to persons wI se pets have recently
been treated.
5/ Agency records indicate that there are no r uaining registrations for lindane flea collars.
6/ N/A = Exposure data not available. The Agency is requiring exposure data under this standard.
7/ Exposure and risks calculated based on current label for use of an MSHIVOSHA approved respirator.
8/ Exposure and risks calculated based on additional protective clothing requirmnents in addition to use of an
MSHPVOSHA approved respirator.
9/ Exposure and risks calculated based on current label without any protective clothing requir fltS.
10/ Exposure and risks calculated based on additional protective clothing requir fltS but without use of an
MSHWOSH approved respirator.
11/ Exposure and risks calculated based on additional protective clothing requir fltS plus use of an MSHA/OSHA
approved respirator.
is
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9. The Agency is concerned about the potential risks to
applicators from the hardwood lumber dipping use, but will not
decide whether to commence a special Review until the acute
and 90—day inhalation studies and the chronic rat study re-
quired under this Standard are evaluated. The Margin of Safety
CMOS), the ratio of the NOEL to exposure, for this use has been
recalculated based on the lower NOEL from the rat subchronic
study. The Agency’s estimate of the upper 95% confidence level
for excess cancer risk from applicator exposure for this use
of lindane is
Rationale : The PD—4 estimated the upper 95% confidence
level for excess cancer risk to hardwood lumber applicators
using protective clothing to be This risk level was
considered acceptable given that the benefits from the use are
significant, the number of applicators is low (1,000—2,000),
and there is a lack o1 alternative physical or chemical control
measures. unlike softwood lumber, hardwood lumber cannot be
heat cured. The one possible alternative pesticide (endosulfan)
which was previously registered for spray application to felled
logs, but not for use as a dip for lumber, may no longer be con-
sidered, since the registrants of endosuif an manufacturing—use
products have recently decided not to support the forestry
(felled logs) use and have removed this use pattern from their
labels.
Based on the NOEL level of 0.3 mg/kg/day established for
kidney effects in the recent subchronic rat study, a Margin
of Safety has been calculated at 230. Given that some workers
may be exposed for 200 days per year, and that extrapolation
of chronic risk based on a subchronic study should allow a
1000—fold safety factor, this Margin of Safety may not be
adequate to protect against kidney damage. Moreover, because
inhalation is the major route of exposure for the hardwood
lumber use, further information on inhalation toxicity (both
acute and 90—day exposure) is needed to better characterize
the risk. Without additional data, the risk calculations are
tentative, and a regulatory decision at this point regarding
initiation of Special Review would be premature. A rat chronic
feeding study is also required to determine the levels of kidney
effects resulting from long term exposure and to investigate
the possibility that these effects might be reversible.
10. The Agency is concerned about the potential risks
to applicators using powered spray equipment for overhead
spraying of ornamentals (commercial application), avocados,
and pecans. The estimates of the upper 95% confidence level
for excess cancer risk for applicator exposure from these uses
are in the range, as in PD—4. The Agency has recalculated
the Margins of Safety (MOS) based on current exposure models
and surrogate studies. The newly calculated Margins of Safety
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for applicators for these uses are as follows: a) commercial
ornamentals 400; b) avocados 200; and c) pecans 90 (applicator)
and 110 (mixer/loader). Reassessment of the Margins of Safety
will be made after receipt and evaluation of an adequate chronic
feeding study in rats and acute and 90—day inhalation studies.
Rationale : PD—4 contained tabulations ot risk associated
with non-dietary exposures to applicators and bystanders. The
ornamental, avocado, and pecan uses were considered as acute
type exposures (only a few days per year). The one product
with the avocado use pattern was voluntarily cancelled after
the issuance of PD—4. Agency records do not show any other
currently registered product with this use pattern, but because
there is still a tolerance for this crop, and another registrant
may decide to support its use, the Agency will continue to
include this crop in this listing of uses of concern.
Considering the few days of applicator exposure per year
that are associated with the ornamental, avocado, and pecan uses,
the Margins of Safety CMOS) from PD—4, which were based on acute
effects, are more representative of the actual exposure risks
from these uses than would be revisions to the MOS based upon
the NOEL from the subchronic toxicity study that was received
at the conclusion of the lindane RPAR. Because the Agency is
using acute studies to estimate acute risks, a 100—fold safety
factor is acceptable. The Agency has, however, recalculated
the MOS using current exposure models and assumptions. Only
minor revisions in the MOS values resulted from these recalcu-
lations (see Table 1). Also, the Agency has calculated the
MOS for a mixer/loader for the pecan use, a calculation that
had not appeared in PD-4. The MOS for this activity (110) is
similar to that for the applicator (90). The estimates of the
upper 95% confidence levels of excess cancer risk to applicators
from these overhead power spray uses remain unchanged from PD-4.
Although the risks are significant, the benefits otfset these
risks and no further regulatory action is necessary.
11. Because of the high potential for dermal exposure to
lindane from those uses which do not require use of protective
clothing, the Agency is requiring a dermal sensitization and a
21—day dermal toxicity test. As in PD—4, the Agency will use
a 10% dermal absorption value for risk calculations. The use
pattern with the highest dermal exposure potential, the dust
products for use only by the military for both clothing and
direct skin application must be supported by an additional
90—day dermal study.
Rationale : Data from a dermal sensitization study and
a 21—day dermal toxicity test are required by 40 CFR 158 to
support the registration of each manufacturing—use product and
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each end-use product which will result in repeated human skin
contact under Conditions of use. Uses for lindane that do not
require protective clothing and which might result in repeated
human skin contact, such as the use on cucurbjts, trigger the
requirements for submission of a dermal Sensitization and a
21—day dernial toxicity study. This Standard uses a value of
10% for derrnal absorption of lindane on the basis of a human
study (conducted by Maibach et al.). The use of lindane dust
on humans and/or clothing is registered for use only by the
military, and the Army has indicated that it will be used Only
on an emergency basis. Nevertheless, because of the high
potential for exposure that results from direct application
to skin or from clothing that is dusted and then immediately
placed in contact with the skin, the Agency is requiring an
additional longer term (90—day) dermal toxicity test. This
use pattern was not considered in the RPAR review of lindane.
12. Several of the use patterns for lindane can result in
potential exposure to lindane vapors, often Over extended periods
of time. Therefore, the Agency is requiring the submission of
of a 90—day inhalation study.
Rationale : Registered uses of lindane include products
intended for epeated indoor uses in the form of aerosols and
sprays. A 90—day inhalation Study is required to support these
uses, as well as the greenhouse uses on food and non—food crops
(which were not part of the RPAR), plus other uses such as soil
treatment and subterranean termite control (Note — the Agency
has already issued a 3(c)(2)(3) Data Call—In Notice for long—term
air monitoring studies to Support the termjtjcjde use). A 90—day
inhalation study is also being required to support the military
use dust products, based on the likelihood of exposure to vapors
from the treated skin and Clothing.
13. The question of lindane’s potential to induce terat..
ogenic and reproduction effects was raised in PD—]. but wag
successfully rebutted by submission of data as discussed in
PD—4. No further teratogenic or reproduction testing with
lindane is required.
Rationale : The potential of lindane to induce terato...
genic and te toxic effects has been adequately characterized
by studies in the rat, rabbit and mouse in which the routes
of administration were by gavage and Subcutaneous injectj 0
No teratogenic effects were noted in these Studies; therefore,
no further teratogenicity testing is requlre for linciane.
Fetotoxic effects were seen only at doses which also
caused maternal toxicity. An oral intubation (gavage) Study
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in rats indicated a NOEL of 5 mg/kg/day for maternal effects,
which is one half the NOEL of 10 mg/kg/day for fetal effects.
Similar results were noted in a gavage study using rabbits,
while a gavage study in mice indicated that both the maternal
and fetal NOEL was 30 mg/kg/day. Doses up to 100 ppm produced
no adverse reproductive effects in rats fed lindane for three
generations. No further reproduction testing is required for
lindane, since available data indicate that protecting mothers
from acute toxic effects will simultaneously protect fetuses
from possible adverse effects.
14. A concern has been raised that the manufacturing
process for lindane may result in the production of dioxins.
The Agency is requiring the submission of analytical results
and a discussion on the formation of unintentional ingredients
produced during manufacturing, packaging, or storage.
Rationale : The Agency does not have complete information
on the specific manufacturing processes for lindane, including
the identification and quantification of all components that
may be produced other than the active ingredient, There is a
possibility that the manufacturing process for lindane could,
theoretically, result in the production of dioxins, at a low
level. However, based on information currently available
to the Agency, the Agency believes that the likelihood of any
dioxins being present in the manufacturing—use product is
remote. To confirm the current information, the Agency is
requiring a narrative Discussion of Formation of unintentional
Ingredients, with special attention to the potential for forma-
tion of dioxins and dibenzOfuraflS, and results of actual analyses
to identify and quantify all components present at greater than
0.1%. After review of this information, the Agency will deter-
mine the potential for occurrence of dioxins or dibenzofurans
in manufacturing—Use products of lindane. If there is reason-
able likelihood for the formation of these compounds, the
Agency will require additional chemical analysis to determine
the identity and quantity of the compounds.
15. i. indane is highly toxic to some aquatic organisms,
but risks from various uses cannot be assessed from data that
are currently available. Submission of data from a tull com-
plement of environmental fate studies is being required at
this time.
Rationale : Available data are insufficient to fully
evaluate the nvironmental fate of lindane. The following
data are required to fully assess the environmental fate and
transport of lindane as well as the potential for exposure:
hydrolysis, photodegradation in water and on soil, aerobic and
anaerobic soil metabolism, leaching and adsorptiort/desorptiOrk,
19
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laboratory volatility, terrestrial and forestry dissipation,
arid accumulation in rotational crops, fish, and non—target
aquatic organisms.
16. The Agency is concerned about the potential for
exposure of non—target aquatic organisms to lindane through
drift or runoff, An aquatic residue monitoring study is
being required at this time to assess the levels of lindane
entering aquatic ecosystems. Additionally, the two labeling
requirements implemented pursuant to the Notice of Intent to
Cancel Pesticide Products Containing Lindane to limit the
exposure of aquatic organisms to lindane will continue.
Specifically, the prohibition against aerial application of
lindane, and the requirement for directions pertaining to the
disposal of dip solutions in accordance with the Resource Recov-
ery and Conservation Act (RCRA), will continue as requirements.
Rationale : The Agency’s original presumption regarding
lindane’s acute toxicity to aquatic organisms was withdrawn
in PD—2/3 because no lindane products were registered for
aquatic uses. At that time, the Agency stated its concerns
regarding the contamination of aquatic habitats by drift or
runoff from terrestrial use sites or from improper disposal
of wastes. In the Notice of Intent to Cancel the Agency
addressed these issues by prohibiting aerial application and
by requiring special disposal instructions (in compliance with
RCRA) for used dip solutions resulting from the hardwood log
and livestock dip use patterns. Since no new information has
been submitted to change the Agency’s conclusions in these
regards, the label statements will continue as a requirement
to protect non—target aquatic organisms. In order to obtain
information relative to the actual levels of lindane entering
the aquatic ecosystem, the Agency is requiring an aquatic
residue monitoring study that includes measurements on both
spray drift (from the spraying of trees, especially pecans),
and runoff (from terrestrial crop applications).
17. Lindane appears to be moderately toxic to some birds
and there is concern that some seed treatments may present a
hazard to birds. Residue levels on other avian food items have
not yet been determined. The Agency is requiring both an acute
avian toxicity study and two subacute dietary studies at this
time. The labeling requirements for statements that exposed
treated seeds may be hazardous to birds and other wildlife,
and to dispose of all treated seeds by burial away from bodies
of water, will continue.
Rationale : The available studies on the acute toxicity of
lindane to birds, although sufficient to characterize lindane
as moderately toxic on an oral basis to starlings and red—winged
20
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blackbirds and practically non—toxic to mallard ducks, do not
meet current Agency requirements (Pesticide Assessment Guide-
lines, Subdivision E, Hazard Evaluation: Wildlife and Aquatic
Organisms; November 1982). Therefore, the Agency is requiring
a single—dose oral study on upland game birds (bobwhite quail).
Since there is the potential for longer term exposure ot
upland game and passerine birds to subacute doses of lindane
by ingestion of treated seeds, two subacute avian dietary
studies, on bobwhite quail and red—winged blackbird, are also
being required at this time. If the data from these studies
indicate that treated seeds present a significant hazard, then
more labeling precautions beyond the present statements will
be necessary. The requirement for an avian reproduction study
is being reserved pending evaluation of the required environ-
mental chemistry data that would indicate the residues of
lindane on avian food items.
18. The Agency is concerned about the potential exposure
of residents and workers to airborne residues of lindane that
may result from termiticide treatment of residences and work-
places. As part of the Agency’s review of termiticides,
certain data requirements have been imposed.
Rationale : As with all termiticide treatments, there
is potential exposure not only to applicators, but also to
occupants of treated buildings. In order to evaluate the
extent and possible effects of this exposure, the Agency has
initiated a review of all termiticides, including lindane.
To date, none of the registrants of lindane manufacturing—use
products has submitted the required long term indoor air
monitoring studies in response to the 3(c)(2)(B) data call—in
letter issued February 23, 1984. Instead, registrants have
elected to delete the termiticide use from the listing of all
the acceptable use patterns for end—use products that may be
formulated from their manufacturing—use products. Since a
data gap still exists, registrants of end—use products have
been notified, through a 3(c)(2)(B) letter, to make known
their intentions of submitting the indoor air monitoring study.
If no end—use product registrant elects to submit the required
data, the use pattern will have to be removed from labeling
or the products in question will be suspended.
19. The Agency is concerned about potential dermal or
inhalation exposure of applicators and residents (including
occupants of treated homes or offices, as well as dog owners
whose pets have been treated with products containing lindane),
resulting from certain use patterns. The Agency is requiring
applicator exposure data for manual seed treatment, livestock
spraying, structural treatment, dog wash, dog shampoo, and dog
dust uses. Exposure data for residents, in the form of air
21
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monitoring studies, are being required for the structural treat—
tuent, dog wash, dog dust, and dog shampoo uses. Exposure data
must also be submitted, in addition to the toxicology data
requirements discussed earlier (items 11 and 12 above), to
support the use of lindane dust by the military on human skin
and/or clothing. Registrants must submit appropriate protocols
for the above studies within 90 days of receipt of this Standard.
Results of the actual studies will be due 6 months after the
protocols are approved by the Agency.
Rationale : Adequate data are not available to characterize
applicator exposure during manual seed treatment, livestock
spraying, structural treatment of buildings, and shampooing,
washing, or dusting dogs with products containing lindane.
Additionally, there are no adequate exposure data, in the form
of air monitoring studies, to determine the levels of pesticide
exposure to residents occupying buildings that have undergone
structural treatment with lindane, or to dog owners following
treatment of their pet with a dog wash, a dog shampoo, or a dog
dust product containing lindane. The current registrations for
military use of lindane dust on human skin/clothing are not
supported by exposure or toxicology data. Since the Agency has
not yet issued Guidelines for exposure studies, registrants are
referred to the four general background articles (“Minimizing
Occupational Exposure to pesticides”, “Dermal Exposure to Pesti-
cides: EPA’S Viewpoint”, “Use of Exposure Data for Risk Assess-
ment”, and “Exposure Assessment for Agricultural Chemicals”)
that are enclosed with this Standard, for information on how
monitoring studies and quantitative exposure assessments are
carried out. Registrants must submit appropriate protocols
for these exposure studies within 90 days.
20. Since the Agency has concerns about the potential
health effects of lindane, and since there are agricultural
uses ot this pesticide that could involve substantial dermal
contact with residues on treated foliage, the Agency is requir-
ing submission of data under 40 CFR 158.140 to make judgements
as to the need for worker protection standards, such as reentry
intervals and personal protective equipment. Until the required
foliar dissipation data are submitted and reviewed, a 24—hour
reentry interval is being required for use of lindane on crops
in which hand labor is required following foliar application.
Rationale : Reentry data are required by 40 CFR 158.140 for
toxic pesticides which have use patterns likely to result in high
dermal and/or inhalation exposure to persons entering pesticide
treated fields. Lindane is a assumed to be a persistent chemical,
and there are agricultural uses that could involve substantial,
prolonged human exposure to the residues on foliage. There are
not sufficient data available for the Agency to make judgements
22
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as to the need for tarmworker protection standards, such as
reentry intervals. The crops for which foliar dissipation data
are required are those whose propagation requires human tasks
that involve substantial, prolonged, dermal contact with pesticide
treated surfaces following foliar application of lindane. Data
to address this concern are lacking and are being required.
Until the required data are submitted and evaluated, a
24—hour reentry interval is required for use on crops in which
hand labor is required following foliar application of lindane.
End—use products with directions for use on such crops must
include the label statements required under PR Notices 83—2
and 84—1. A 24—hour reentry interval must be included in the
required written or oral warnings given to farmworkers.
21. The Agency has identified certain data requirements that
will receive priority review when received.
Rationale : Certain data are essential to the Agency’s
assessment of this pesticide and its uses and/or may trigger
the need for further studies which should be initiated as
soon as possible. The following studies have been identified
to receive priority review as soon as they are received by
the Agency:
Sl58.135 Toxicology
81—3 Acute Inhalation Toxicity
82—4 90—Day Inhalation
83—1 Chronic Toxicity (rat)
83—2 Oncogenicity (rat)
85—1 Blood Dyscrasias (laboratory animal)
S158.125 Residue Chemistry
171—4 Nature of Residue in Plants
171—4 Nature of Residue in Livestock
171—4 Magnitude of the Residue
(all crops with this requirement)
S158.130 Environmental Fate
161—1 Hydrolysis
161—2 Photodegradation in Water
161-3 Photodegradation on Soil
162-1 Aerobic Soil Metabolism
163—2 Volatility (laboratory)
165—1 Rotational Crops (confined)
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S158.130 Environmental Fate (Continued)
165—4 AccumulatiOn in Fish (laboratory)
Exposure to Applicators
Exposure to Residents
Human Skin/Clothing Exposure
S158.145 Ecological Effects
70—1 Special Test — Aquatic Residue Monitoring
71—1 Acute Avian Oral Toxicity
71—2 Subacute Avian Toxicity
72—1 Freshwater Fish Toxicity
72—2 Acute Toxicity to Freshwater Invertebrates
72—3 Acute Toxicity to Estuarine & Marine Organisms
72—4 Fish Early Life Stage
72—4 Aquatic Invertebrate Life Cycle
141—2 Honey Bee — Toxicity of Residues on Foliage
24
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D. Criteria for Registration under the Standard
To be acceptable for registration under this Standard,
manufacturing—use products must contain lindane as the sole
active ingredient (solvents or diluents should be declared as
inerts), bear required labeling, and conform to the product
composition, acute toxicity limits, and use pattern require-
ments as indicated in Section E of this document. The appli—
icant for registration or reregistration of products subject
to this Standard must comply with all terms and conditions
described in it, including submission of an up—to—date
Confidential Statement of Formula, submission of revised
labeling, commitment to fill data gaps on the schedule
specified by the Agency and, when applicable, offer to pay
compensation as required by 3(c)(l)(D) and 3(c)(2)(D) of the
Federal Insecticide, Fungicide and Rodenticide Act (FIFRA),
as amended, 7 U.S.C. 136(c)(l)(D) and 136(c)(2)(D).
E. Acceptable Ranges and Limits
1. Product Composition Standard
To be registered under this Standard, manufacturing—
use products (MP) must contain lindane as the sole active
ingredient (solvents or diluents should be declared as
inerts). Technical products must contain at least 99%
lindane. Each MP formulation proposed for registration
must be fully described with an appropriate certification
of limits, stating maximum and minimum amounts of the
active ingredient and any intentionally—added inert
ingredients which may be present in the product.
2. Acute Toxicity Limits
The Agency will consider registration of technical
grade and manufacturing—use products containing lindane,
provided that the product labeling bears the appropriate
precautionary statements for the acute toxicity category
in which each product is placed.
3. use Patterns
To be registered under this Standard, manufacturing—
use products containing lindane may be labeled for form-
ulation into end—use products only for the use patterns
and commodities listed in the “EPA Index to pesticide
Chemicals”, section Il—H of this Standard.
Note that each of the agricultural commodities, as
well as any associated processed food/feed items, has
25
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outstanding residue chemistry data requiremeflt to support
tolerances. In addition, other data requirements pertinent
to the type of use pattern may be applicable, as indicated
in Tables A and B. No use may be included on the label
where the registrant(s) fails to agree to comply with the
data requirements in either Table A or Table B for that
use pattern.
F. Required Labeling
All manufacturing_use and end—use lindarke products must
bear appropriate labeling as specified in 40 CFR 162.10. This
Guidance Document contains information on label requirem 5
All labeling changes must be accepted by the Registra j
Division, Office of Pesticide Programs, and must appear on
all products released for shipment after June 30, 1986 . All
labeling changes must must appear on all products in channels
of trade as of December 30, 1986 . In addition to the require-
ments of 40 CFR 162.10, the following items must appear on the
labeling:
1. Labeling for Manufacturing _ use Products
a. The ingredient statement for manufacturing_use
products must declare the active ingredje as:
Lindane (gamma isomer of benzene hexachlorjde)
b. Labels tor manufacturing_use products must bear
the following identifying phrase directly beneath the
product name:
“An insecticide for formulating use only”
C. Labels for manufacturing_use products must bear
statements reflecting the compound’s acute hwnan
toxicity. Lindane is in Toxicity Category it by the
oral route of exposure; the required Precautionary
statements associated with this category are specified
in 40 CFR 162.10.
d. All manufacturing_use lindane products must
state in the directions for use that they are intended
for formulation into end—use products for the af ore—
mentioned use patterns. Labeling must specify sites,
which are listed in Use Patterns , Section E,3 A
limiting factor willbe data thit Supports these use
patterns. No use may be included on the label where
the registrant fails to agree to comply with the
data requirem g in either Table A or Table B for
that use pattern.
26
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e. The directions for use must include the following
statement:
“Formulators using this product are responsible for
obtaining EPA registration for their formulated
product(s) St.
f. Detailed instructions for formulating may be omitted
from the manufacturing—use product label provided that
information pertinent to the needs of the formulators,
including, but not limited to, physical and chemical
properties of the product is included on the labeling.
If such information is stated in labeling other than
directly on the product label, a reference statement
such as “Refer to Technical Bulletin for formulating
and other information” must appear on the label and the
technical bulletin must be submitted with the product
label for Agency review.
g. Labels for manufacturing—use products must bear the
following statements under the heading “Environmental
Hazards”:
“This pesticide is toxic to fish, birds and
other wildlife. DO not discharge etfluent
containing this active ingredient into lakes,
streams, ponds, estuaries, oceans or public
waters unless this product is specifically
identified and addressed in an NPDES permit.
DO not discharge effluent containing this
product to sewer systems without previously
notifying the sewage treatment plant authority.
For guidance, contact your State Water Board
or Regional Office of the EPA.”
h. Lindafle products are “toxic” hazardous wastes
when discarded. The following pesticide disposal
statement must appear in the “STORAGE AND DISPOSAL”
section of the label:
“PESTICIDE DISPOSAL Pesticide wastes are toxic.
Improper disposal of excess pesticide or rjngate
is a violation of Federal law. If these wastes
cannot be disposed of by use according to label
directiOnS, contact your State Pesticide or
Environmental Control Agency, or the Hazardous
Waste representative at the nearest EPA Regional
Office for guidance.”
27
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2. Labeling for End—Use Products*
a. Products with directions for use for avocados,
pecans, livestock (sprays), forestry, Christmas trees,
commercial ornamentals, structural treatment, dog dusts,
and dog shampoos are classified for restricted use based
on oncogenicity.
The following “Restricted Use” statement must appear
on the label of all lindane products that are classified
for restricted use:
RESTRICTED USE PESTICIDE
The use of this product may be hazardous to
your health. This product contains lindane,
which has been determined to cause tumors in
laboratory animals. Risks can be reduced by
closely following the use directions and
precautions, and by wearing the protective
clothing specified elsewhere on this label.
For retail sale to and use only by Certified
Applicators or persons under their direct
supervision and only for those uses covered
by the Certified Applicator’s certification,
b. The ingredient statement for all end—use products
must declare the active ingredient as:
Lindane (gamma isomer of benzene hexachioride)
c. Products with directions for use on commercial
ornamentals, avocados, pecans, livestock (sprays
only), forestry, and Christmas trees must bear the
following statement:
“Aerial application of liridane is prohibited.”
d. Pursuant to PR Notices 83—2 and 84—1, the worker
protection (tarmworker safety) statements specified
in those Notices must appear on the labeling of all
agricultural use products with directions for foliar
application to crops whose culture requires hand labor.
A 24-hour reentry interval is required in the interim
until the required reentry data has been submitted
and reviewed.
*All labeling requiremen j for lindane smoke fumigation devices
for indoor use set forth in the Amendment of Notification of
Intent to Cancel (50 FR 5424, February 8, 1985) remain in effect
until cancellation of that use becomes effective in May, 1986.
28
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e. products with directions for use for avocados,
pecans, livestock sprays, commercial ornamentals,
Christmas trees, forestry, and hardwood logs and
lumber must bear the following protective clothing
statement:
“Applicators must wear water resistant hat,
lightweight protective suit or coveralls,
unlined waterproof gloves (natural rubber,
neoprene, or polyethylene), and unlined
lightweight boots. Mixer/loaders must wear
goggles or a face shield, waterproot apron,
and unlined waterproof gloves.”
f. products with directions for use for spraying
uninhabited buildings (warehouses, etc.) and/or
empty storage bins (including grain bins) must bear
the following protective clothing statement:
“Applicators must wear water resistant hat,
lightweight protective suit or coveralls,
unlined waterproof gloves (natural rubber,
neoprene, or polyethylene) unlined light-
weight boots, and an MSHA/OSHA approved
respirator. Mixer/loaders must wear goggles
or a face shield, waterproot apron, and
unlined waterproof gloves.”
g. products with directions for use for structural
treatment must bear the following protective clothing
statement:
“Applicators must wear water resistant hat,
lightweight protective suit or coveralls,
unlined waterproof gloves (natural rubber,
neoprene, or polyethylene) and unlined
lightweight boots. MSHA/OSHA approved
respirators are required for applications
in enclosed areas such as crawl spaces.
Mixer/loaders must wear goggles or a face
shield, waterproof apron, and unlined
waterproof gloves.”
h. All indoor structural pest control products must
include a statement that lindane must not be applied to
currently occupied areas (i.e. living or working areas)
of the home or other buildings. Characterization of a
site as “currently occupied” depends upon the intended
function of the area (such as living areas, including
finished basements and finished attics, and workplaces)
and does not depend U Ofl whether or not there are
occupants present at the time of application.
29
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i. products with directions for use as dog shampoos
or dog dips must bear the following protective clothing
statement:
“Applicators must wear long sleeved shirt, long
pants, elbow—length waterproof gloves, waterproof
apron, and unlined waterproof boots.”
j. Products with directions for use as a dog dip must
bear the following precaution:
Improper dilution of this product could cause
serious injury to your dog.”
k. products with directions for use as dog dips for pests
other than mites must bear the following statements:
1) The front panel must include the following:
“AN INDIVIDUAL APPLICATOR MUST NOT APPLY THIS
PRODUCT MORE THAN TWELVE TIMES PER YEAR.”
2) Beneath the product name on the front panel,
and in the same type size as the signal word:
“FOR KENNEL, COMMERCIAL, FARM AND SPORT DOG
USES ONLY”
3) The last two sentences of the directions for
use must state:
“An individual applicator must not use this
product more than twelve times per year.
Each treatment of three dogs or fewer should
be considered one use.”
4) The label must include the following statement:
“Children under the age of thirteen should not
be allowed to handle or apply this product.”
5) The label must include the following statement:
“Used dip solutions must be disposed of in
accordance with the Resource Conservation and
Recovery Act (RCRA). It the applicator generates
more than 1000 kg of used dip solution per month
or more than 1000 kg used dip solution in combin-
ation with other hazardous waste, the material
must be treated as a hazardous waste subject to
subpart C of RCRA. Any user who wishes to treat,
store or dispose of hazardous waste must obtain
a permit to serve as a hazardous waste facility
pursuant to RCRA.”
30
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1. Products with directions for use as a dog dust
must bear the following statement:
“This product must be applied in a well—ventilated
area.”
m. Products with directions for use for moth sprays
must bear the following protective clothing statement:
“Applicators must wear an MSHA/OSHA approved
respirator.”
n. Products with directions for use for manual
seed treatment must bear the following statements:
“Applicators must wear long sleeved shirt.,
long pants, gloves, and a disposable paper
dust mask covering at least one third of face.
This product must be applied in a well-
ventilated area.”
[ Note — labeling for products containing
lindane in combination with a fungicide
which requires use of a respirator should
include the MSHA/OSHA respirator statement
appropriate to the tungicide instead of
the paper dust mask requirement.1
0. All seed treatment products must bear the following
wildlife precaution:
“Exposed treated seed may be hazardous to birds
and other wildlife. Dispose ot all excess treated
seeds by burial away from bodies of water.”
p. Registrants should refer to the footnotes of the
generic residue chemistry data requirements (pages
180—222 of this Standard) for additional labeling
revisions for specific crop/livestock uses.
q. In the absence of field crop rotation data, the
crop rotation restriction below must be placed on
all products which may be used in a situation where
rotation with crops used for food or feed that are
not registered with lindane may occur:
“Do not plant any food or feed crop in rotation
after a field treatment with lindane unless it
is a registered use for lindane.”
31
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r. Recommendations for tank mixes with other pesticides
that do not have a tolerance established for the specified
crop must not appear on labeling.
s. All products with directions for use on field crops
and/or homeowner vegetable gardens must include the
following statement:
“Soil application: Do not make soil application
to root crops, which might absorb a musty flavor.
Do not apply in soil which will be planted to
root crops (except potatoes) within 1 year.
Do not use in soil which will be planted to
potatoes within 2 years.”
t. All indoor—use products must include the following
statement:
“Do not apply this product in edible product areas
of food processing plants, restaurants, or other areas
where food is commercially prepared or processed. Do
not use in serving areas while food is exposed.”
u. Products with directions for use for homeowner
use on ornamentals must bear the following protective
clothing statement:
“Applicators must wear long sleeved shirt,
long pants, waterproof gloves, full foot
covering (such as shoes or boots), and
head covering (such as a hat).”
v. All residential—use products (including shelf
paper and sprays) must bear the following statements
in the directions for use:
“Avoid exposure to children. Do not allow
children to handle or apply this product.”
[ NOTE - Lindane products meeting the criteria of
40 CFR 162.16 (Products Requiring Special Packaging)
and with concentrations of lindane greater than 6.5%
must be in child—resistant packaging.]
w. It the residential—use product is a spray or a
liquid, the label must include the additional statement:
“Do not allow children or pets in treated areas
until surfaces are dry.”
32
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x. All products with outdoor uses must include
following Environmental Hazards statement:
“This pesticide is toxic to fish, birds, and
other wildlife. Do not apply directly to water
or wetlands. Drift and runoff from treated areas
may be hazardous to fish in neighboring areas.
Do not contaminate water by cleaning of equipment
or disposal of wastes.
This pesticide is highly toxic to bees exposed to
direct application. Applications should be timed
to coincide with periods of minimum bee activity,
usually between late evening and early morning.”
y. Labels with directions for use as a dip for
livestock and hardwood logs or lumber must include
the following statement:
“Used dip solutions must be disposed of in
accordance with the Resource Conservation and
Recovery Act (RCRA). If the applicator generates
more than 1000 kg of used dip solution per month
or more than 1000 kg used dip solution in combin-
ation with other hazardous waste, the material
must be treated as a hazardous waste subject to
subpart C of RCRA. Any user who wishes to treat,
store or dispose of hazardous waste must obtain
a permit to serve as a hazardous waste facility
pursuant to RCRA.”
z. Lindane products are “toxic” hazardous wastes when
discarded. The following pesticide disposal statement
must appear on all labels (except products intended for
household use only):
“PESTICIDE DISPOSAL: pesticide wastes are toxic.
Improper disposal of excess pesticide, spray
mixture, or rinsate is a violation of Federal law.
If these wastes cannot be disposed of by use
according to label instructions, contact your
State pesticide or Environmental Control Agency,
or the Hazardous Waste representative at the
nearest EPA Regional Office for guidance.”
33
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G. Tolerance Reassessment
There are over 40 registered uses of lindane for food.
By far the most significant are seed treatments (48% of all.
use) and livestock (20% of all use). Other major uses include
pecans (3%), pineapples (2%), and cucurbits (1%). Many of
the registered uses are not active, i.e. do not appear on
any current product label.
Using the conventional method of total maximum residue
contribution (TMRC), a 1.4189 mg/day intake can be computed.
Because of inadequate analytical methods and incomplete charac-
terization of the nature of the residues in plants and animals,
the tolerances are virtually unsupported by residue data meet-
ing current standards. In addition, lack of a good chronic
feeding study means that a conventional ADI cannot be estab-
lished. Additional residue data and a rat chronic teeding
study will be required under this Registration Standard to
support the existing tolerances.
For the present time, the best available data for deter-
mining a provisional acceptable daily intake (PADI) is the new
subchronic 90-day feeding study in the rat which was received
shortly before the RPAR was completed. This study, which meets
core guideline criteria, showed that lindane caused toxic
changes primarily in the kidneys but also in the liver of male
and female rats. Renal changes were irreversible with a NOEL
of 4 ppm in the diet equivalent to 0.3 mg/kg bodyweight/day.
Using this latter value, and a safety factor of 1,000 for a
subchronic study, the PADI is 0.0003 mg/kg/day and the maximum
permissible intake (MPI) for a 60 kg person is 0.018 mg/day.
Based upon a TMRC of 1.4189 ntg/day/1.5 kg of diet, the percent
of the MPI used up is 7,883%. It is this high percentage of
MPI used up that is of major concern. Based on the TMRC method
of calculation, the estimate of the upper 95% confidence levels
of excess cancer risk is 2xl0 2 .
Both PD-2/3 and PD—4 used figures derived from FDA
Total Diet Composites, rather than the TMRC method of summing
the established tolerances, to more accurately reflect actual
residues of lindane in foodstuffs. FDA has also concluded
that regulatory compliance samples, as well as the Total Diet
Composite Samples collected over several years, indicate that
dietary intakes of lindane in adults, infants, and toddlers
are within acceptable limits. If FDA market basket fi jures
are used, then the average daily consumption of lindane is
0.000002 mg/kg, the percentage of the MPI used up is 0.7%,
and the estimate of the upper 95% confidence levels of excess
cancer risk is 2x10 6 .
34
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These dietary risk estimates do not reflect the seed
treatment uses, since these uses were previously considered
non—food uses and no tolerances exist for them. Present
Agency policy now categorizes seed treatment as a food use
unless a radiolabeled study shows that no residues remain
in the edible portion of the specific food crop grown from
treated seed. While residues in edible portions are likely
to be minimal, any additional tolerances which are required
to support the seed treatment uses would further inflate the
percent of the MPI being used.
Selectively adjusting the TMRC to reflect percent of
crop treated would reduce the percent of MPI used, since many
of the tolerances are not being used at all and others (such
as the livestock uses) are not used on all animals. Further
reductions would occur if tolerances were lowered to reflect
actual residues.
The Agency believes that Special Review is not warranted
at this time in regard to dietary risk, considering the fact
that crop residue data are lacking, and plant and animal
metabolism information to characterize the parent compound
and metabolites is missing. Also, an adequate chronic feed-
ing study to assess the actual NOEL for dietary exposure is
missing. A decision as to whether further regulatory action
is necessary will be deferred until all the toxicology and
residue data needed to conduct a complete tolerance reassess-
ment are submitted and reviewed. The missing data to do a.
tolerance reassessment will receive high priority for review
upon receipt.
35
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SUMMARY OF PRESENT TOLERANCES
Tolerances (part per million)
International
Commodity United States Canada Mexico (Codex )
Apples 1.0 3.0 1.0 0.5
Apricots 1.0 3.0 — —
Asparagus 1.0 3.0 1.0
Avocados 1.0 3.0 1.0 —
Broccoli 1.0 3.0 1.0 —
Brussels Sprouts 1.0 3.0 — 0.5
Cabbage 1.0 3.0 1.0 0.5
Cattle, fat 7.0 2.0 — 2.0
Cauliflower 1.0 3.0 — 0.5
Celery 1.0 3.0 1.0 —
Cherries 1.0 3.0 — 0.5
Collards 1.0 3.0 —
Cucumbers 3.0 3.0 3.0
Eggplant 1.0 3.0 1.0
Goats, fat 7.0 2.0 — —
Grapes 1.0 3.0 1.0 0.5
Guavas 1.0 3.0 1.0 —
Hogs, fat 4.0 2.0 — 2.0
Horses, tat 7.0 — —
Kale 1.0 3.0 —
Kohlrabi 1.0 3.0 1.0
Lettuce 3.0 3.0 3.0 2.0
Mangoes 1.0 3.0 1.0 —
Melons 3.0 3.0 3.0 —
Mushrooms 3.0 3.0 —
Mustard Greens 1.0 3.0 —
Nectarines 1.0 — —
Okra 1.0 3.0 1.0
Onions, dry bulb only 1.0 3.0 1.0 —
Peaches 1.0 3.0. 1.0 —
Pears 1.0 3.0 1.0 0.5
Pecans 0.01 — 0.01 —
Peppers 1.0 3.0 1.0
Pineapples 1.0 3.0 1.0 —
plums, mci. Prunes 1.0 3.0 — 0.5
Pumpkins 30 3.0 —
Quinces 1.0 3.0
Sheep, fat 7.0 2.0 — 2.0
Spinach 1.0 3.0 1.0 2.0
squash 3.0 3.0 3.0 —
Summer Squash 3.0 3.0 3.0 —
Strawberries 1.0 3.0 1.0 3.0
Swiss Chard 1.0 3.0 — —
Tomatoes 3.0 3.0 3.0 2.0
36
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EPA Index to Pesticide Chemicals
LINDANE (GAMbIA ISOMER OF BENZENE IIEXACHLORIDE)
TABLE OF CONTENTS
Site Name Pag
TERRESTRIAL FOOD CROP
( Agricultural Crops)
Alfalfa 4
Apple 4
Apricot 6
Asparagus 6
Barley 6
Beans
Beans, Succulent 8
Beets 9
Broccoli 10
Brussels SproutS 10
10
Carrots 11
Cauliflower 10
Celery 12
Cherry 13
Clover 4
Collards 14
Corn 1.5
Cotton 16
Cucumber 18
Eggplant 19
Flax 20
Grapes 21
Issued: 6—05—84 1 1 1—009001—i
37
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EPA Index to Pesticide Chemicals
LINDANE (G ZIMA ISOMER OF BENZENE HEXACULORIDE)
TABLE OF CONTENTS
Site Name Page
Kale 21
Lentils 22
Lettuce 22
Melons (including Cantaloupe, and Wateri e1on) 24
Oats 24
Okra 26
Onion, Dry 27
Peach 28
Pear 29
Peas (including Cowpeas) 30
Pecan 31
Peppers 32
Plum 33
Prune 33
Pumpkin
Radish 34
35
Safflower 36
(including Milo Sorghum) 37
Soybeans 38
Spinach 39
Squash 40
Strawberry 41
Sudangrass 41
Sugar Beets 42
Issued: 6—05—84 111—009001—2
38
I
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EPA index to Pesticide Chemicals
LINDIANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
TABLE. OF CONTENTS
Site Name Page
Sunf lower 42
Tomato 44
Wheat 45
TERRESTRIAL NON-FOOD CROP
( Agricultural Crops)
Tobacco 47
( Ornamental Plants )
48
Aspen 48
Austrian Pine 49
Azalea 49
Beech 50
Birch 51
Boxelder 51
Boxwood 52
California Red Fir 52
Camellia 53
Chestnut 53
Christmas Tree Plantations 54
Chrysanthe im 54
Cottonwood 54
Coulter Pine 52
Daffodil 55
Pine 52
Issued: 6—05—84 111—009001—3
39
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
TABLE OF CONTENTS
Site Name Page
Dogwood 55
s-Fir 52
Elm (including English Elm and Scotch Elm) 56
57
Flowering Cherry 57
Flowering Ornamental Fruit Trees 58
Gladiolus 58
Hawthorn 59
Hemlock
Holly 60
Horsechestnut 51
Hyacinth 60
Iris 60
Japanese Black Pine 61
Juniper 61
Lilac 61
Lilies 62
Linden 51
Locust (including Black Locust) 63
Maple 64
Monterey Pine 52
Mountainash 64
Narcissus 60
64
Oak 65
Issued: 6—05—84 III- OO900l4
40
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EPA Index to pesticide heinicals
LINDANE (CA}IMA ISOMER OF BENZENE HEXA 1 CHLORIDE)
TABLE OF CONTENTS
Site Name Page
Ornamental and/or Shade Trees 65
Ornamental Deciduous Trees 66
Ornamental Evergreens 66
Ornamental Lawns 67
Ornamental Plants 69
Ornamental Woody Shrubs 72
Pine 73
Ponderosa Pine 52
Poplar 78
Primrose 78
Pyracantha 78
Rhododendron Hybrids/Cultivars 79
Rose 81
Scotch Pine 81
Spruce (including Norway Spruce and White Spruce) 81
ine 52
Sycamore 82
Taxus Compacta 59
Tulips 83
White Fir 52
White Pine 81
Willow 83
Issued: 6—05—84 111—009001—5
41
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EPA Index to Pesticide Chemicals
LINDANE (GA}IMA ISOMER OF BENZENE HEXACRLORIDE)
TABLE OF CONTENTS
Site Name Page
GREENHOUSE FOOD CROP
( Agricultural Crops)
Cucumber 84
Lettuce 84
Tomato 84
GREENHOUSE NON—FOOD CROP
( Ornamental Plants and Forest Trees)
Ornamental Plants (including Azalea, Camellia, Carnation,
Chrysanthemum, Gardenia, Geranium, Gladiolus, Primrose,
Rhododendron, Rose, and Snapdragon) 85
FORESTRY
( Ornamental Plants and Forest Trees)
Forest Trees 88
Pine (Forest) 89
DOMESTIC OUTDOOR
( Household)
Domestic Dwellings, Outdoor 90
INDOOR
( Processed or Manufactured Products, and Food or Feed Containers or
Dispensers)
Food/Feed Storage Areas — Empty 91
Grain/Cereal/Flour Bins Feed/Food — Empty 92
( Pets and Domestic Animals)
( Animals and Their Man—Made Premises)
Beef Cattle 92
Issued: 6—05—84 111—009001—6
42
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
TABLE OF CONTENTS
Site Name -. Page
Dogs 96
Goats 92
Hogs 92
Horses 97
Mules 97
Sheep 92
(Animal Premises)
els 98
Fox Hutches 98
Garbage Dumps (livestock premises ) 98
99
Livestock Building and Pens 99
Livestock premises (manure treatment ) 98
( Agricultural Premises and Equipment)
Agricultural Premises 100
( Household)
Domestic Dwellings, Contents 100
Domestic Dwellings, Indoor 101
( Wood or Wood Structure Protection Treatments)
Finished Wood Products 102
Terrestrial Structures 102
Unseasoned Forest Products 109
( Noncrop, Wide Area, and General Indoor/Outdoor Treatments)
Wide Area General Indoor/Outdoor Treatments 111
Issued: 6—05—84 111—009001—7
43
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EPA Index to Pesticide Qieinicals
LINDANE (GANMA ISOMER OF BENZENE HEXACHLOR.IDE)
TABLE OF CONTENTS
Site Name Page
( Commercial and Industrial Uses)
Commercial Establishments 112
( Domestic and Human Use)
Human Bedding, Blankets, Mattresses 113
Human Clothing 113
Issued: 6—05—84 111—009001—8
44
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EPA Index to Pesticide Chemicals
c 00 900 l LINDANE (GAMMA ISOMER OFBENZENE HEXACHLORIDE)*
TYPE PESTICIDE : Insecticide, Acaricide
FORMULATIONS :
Tech (99%, 99.5%, 100%)
Ft (10%, 20%, 25%, 95%)
D (0.5%, 0.75%, 1%, 12.5%, 16.6%, 18.75%, 25%, 752)
wP (3%, 6%, 9%, 10%, 25%, 75%)
WP/D (0.5%, 1%, 25%, 75%)
Impr (0.27%, 2.3%, 5.6%, 11.2%)
EC (0.35 lb/gal, 0.36 lb/gal, 1 lb/gal, 1.6 lb/gal, 1.63 lb/gal, 1.65
lb/gal, 1.66 lb/gal, 1.7 lb/gal, 1.75 lb/gal, 0.45%, 0.5%, 1%,
1.68%, 1.96%, 2%, 2.5%, 3.9%, 4.25%, 4.6%, 5%, 6.5%, 6.63%, 8.82%,
102, 10.68%, 10.94%, 11%, 11.14%, 11.34%, 11.372, 12.2%, 12.29%,
12.5%, 12.8%, 12.89%, 17%, 20%, 25%, 40%)
FIC (1%, 30%, 40%)
SC/L (1.63 lb/gal, 20%)
RTU (2.67 lb/gal, 4 lb/gal, 0.05%, 0.097%, 0.1%, 0.2%, 0.25%, 0.32, 0.5%,
1%, 2%, 3%, 5%, 8.6%, 10.5%, 14.6%, 25%)
PrL (0.25%, 0.75%, 3%)
GENERAL WARNINGS AND LIMITATIONS : Lindane products registered for the
following uses are classified for restricted use: commercial ornamentals,
pecans, livestock (spray), forestry, Christmas trees, structural treat-
ments, dog shampoos, and dog dusts. Labels claiming such uses must con-
tain the following language: RESTRICTED USE PESTICIDE. For application
only by or under the direct supervision of a certified applicator.
Applicators must wear the following protective clothing during the appli-
cation process: a lightweight protective suit or coveralls; water—resist
ant hat; unlined, waterproof gloves; and unlined, lightweight boots.
Mixers and loaders must also wear goggles or a face shield, waterproof
gloves and a waterproof apron. In addition to the above protective
clothing requirements, some specific uses require explicit warning:
a) For dog dust use, lindane should be applied in a well—ventilated area.
b) For structural treatment, applicators working in enclosed areas such
as crawl spaces, must wear a respirator approved by Occupational
Safety and Health Administration (29 CFR 1910.134).
c) For dog shampoos, applicators must wear the following protective
clothing during the application process: waterproof, elbow—length
gloves; a waterproof apron; and unlined, waterproof boots.
For homeowner ornamentals, applicators must wear: long—sleeved shirt,
long pants, waterproof gloves, full foot covering, and a head covering.
For hardwood logs and lumber, applicators must wear: lightweight protec-
tive suit or coveralls; unlined, waterproof gloves; and unlined, light-
weight boots.
For dog dips, applicators must wear: elbow—length, waterproof gloves; a
waterproof apron; and unlined, waterproof boots. Improper dilution could
cause injury to pets. Children should not be allowed to handle or apply
this product.
For moth sprays, applicators must wear MSHA/OSHA—approyed cartridge res-
pirators.
*1 indane
Issued: 6—05—84 111—009001—1
Provisional Update: 8—19—85 45
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE).
GENEI AL WARNINGS AND LIMiTATIONS (continued)
For seed treatment, applicators who apply this product manually or without
the use of a closed—system treatment procedure must wear: long—sleeved
shirt; long pants; gloves; and a disposable, paper dust mask which covers
at least one—third of the face. The product must be applied in a well—
ventilated area.
For other household uses (shelf paper and household sprays), do not allow
children to handle or apply this product. Children and pets should not
be allowed in treated areas until sprayed surfaces are dry.
Aerial application of lindane is prohibited.
Any lindane products registered for residential use (dog dips, household
products) that contain more than 6.5 percent active ingredient must comply
with EPA’s child resistant packaging regulations set forth in 40 CFR
162.61 and 46 CFR 15104.
Bee Caution :
Lindane is highly toxic to bees exposed to direct treatment or to residues
remaining in the treated area. Do not apply when bees are actively visit-
ing in the treatment area. Applications should be timed to provide the
maximum possible interval between treatment and the next period of bee
activity.
Agricultural Crop Tolerances (other than those listed in the text):
Avocados - I ppm
Guavas — I ppm
Kohlrabi - 1 ppm
Mangoes — 1. ppm
Mushrooms — 3 ppm
Mustard Greens — I ppm
Nectarine — I ppm
Quinces — I ppm
Swiss Chard — 1 ppm
Definition of Terms :
HAL — Multiple active ingredient(s)
* Tablespoons actual: A hypothetical quantity computed by multiplying the
number (or equivalent number) of tablespoons of product by the concen-
tration of lindane in the formulation.
**Computed from tablespoons/teaspoons dosage.
# Exact computation of actual dosage is not possible because of the lack
of weight/volume information on the label. Extrapolation from other
formulations reveals that the dosage from this label appears to fall
within the range shown by formulations with known weight/volume ratios.
Issued: 6—05—84 111—009001—2
46
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EPA Index to Pesticide Chemicals
LINDANE (GA1o ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
TERRESTRIAL FOOD CROP
( Agricultural Crops)
General Warnings and Limitations : Apply when pests first appear in
threatening numbers and repeat at regular day intervals or as needed,
unless otherwise specified. Consult your State Agricultural Extension
Service for additional information on compatibility, dosage, timing, and
uses. Do not plant any food or feed crop in rotation after a field
treatment with lindane unless it is a registered use for lindane.
Soil Application : Do not make soil application to root crops which
might absorb a musty flavor. Do not apply in soil which will be planted
to root crops (except potatoes) within 1 year. Do not use in soil which
will be planted to potatoes within 2 years.
Seed Treatment : Do not use treated seed for food, feed, or oil purpos-
es. Treated seed should be labelled in accord with all the applicable
requirements of the Federal Seed Act. The Federal Seed Act requires
that seed treated with a pesticide must contain a dye which imparts an
unnatural color to the seed if the seed is intended to be moved in in-
terstate conunerce. Exposed treated seed may be hazardous to birds and
other wildlife. Dispose of excess seed by burial away from bodies of
water.
Only seed of high germination with good vigor should be treated with
lindane. Poor seed may suffer greater injury. Treat seed not over 6
weeks before planting. Store treated seed in a dry place until planted
so that excess moisture will evaporate. If seed is stacked when wet,
heat may develop which could impair germination.
The common methods of treating seed are slurry, planter box, and dry
method. For slurry treatment, apply in a slurry—type treater specifi-
cally designed and approved for that purpose or apply by hand in any
suitable mixing equipment, such as home—made rotary drums. For planter
box method, fill the box only half full of seed and half the required
amount of lindane and mix thoroughly with a stick. Then add the remain-
der of the seed to the box and add the rest of the required amount of
lindane to the seed, again mixing thoroughly. For dry treatment, mix
product with the seed in any commercial or barrel treater, until thor-
oughly coated. Certain wettable powders may be applied dry. Wettable
powder/dusts may be applied as a slurry, dry, or in the planter box.
Dosage rates are given in ounces of active ingredient per 100 pounds of
seed except for those given in ounces per bushel or those otherwise
specified.
Labels claiming control of seed—infesting insects using slurry or dry
method may be tank mixed with one or a combination of: hexachloroben—
zene; thirain; captan; or carboxin.
Labels claiming control of seed—infesting insects using planter box
method may be formulated with one or a combination of : maneb; diazinon;
captan; or carboxin.
Issued: 6—05—84 111—009001—3
47
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EPA Index to Pesticide Chemicals
LINDANE (CAIOIA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest 2 and Tolerance, Use, Limitations
Formulation(s )
/23001AA Alfalfa No tolerance established.
/23003AA Clover Seed treatment through 0.5 ounce
per 100 pounds of seed.
INAKABA Seedcorn beetle 0.5 oz/l0O Seed treatment. Apply by slurry,
IOACAHA Seedcorn maggot lb/seed planter box, or dry method. For
INBPAAA White grubs (25% D) slurry method, apply 1 pint of
INAVAAA Wireworms (25%, 75% wP) liquid slurry per 100 pounds of
(25%, 75% seed.
WP/D)
or
2 fl.oz 25%
EC, RTU/lOO
lb/seed
(25% EC)
(25% RTU)
or
1.33—2 fl.oz
30% FIC/l00
lb seed
(30% F1C)
or
1—1.33 fl.oz
40% F1C/lOO
lb seed
(40% F1C)
/O4001AA Apple 1 ppm
60 day preharvest interval through
0.65 pound per acre of dust fonnu—
Lation or 3.6 pounds of spray formu-
lations per acre for foliar applica-
tion.
Do not apply after first cover as
off flavor may result.
For emulsifiable concentrate formu-
lations, apply a minimum of 300 gal-
lons of water per acre.
IRACAAA Aphids (including 0.35—0.65 Foliar application. For rosy apple
rosy apple aphid) lb/A aphid , apply as late as petal fall.
INAMADA Flea beetles (1% D)
IVABAAA Grasshoppers or
IQAMARA Lygus bugs 0.25 lb/lOO
INASAVA Plum curcullo gal
INOAAAA Thrips or
0.75—1 lb/A
(25% VP)
or
Issued: 6—05—84 III—00900 1-4
48
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EPA Index to Pesticide Chemicals
LINDANE (GA 1A ISOMER OF BENZENE HEXACHLORIDE>
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Apple (continued)
0.02 oz**/gal
or
0.3 lb/lOO
gal
(1.6 lb/gal
EC)
(20% EC)#
or
0.5 Pt 40%
EC/l00 gal
(40% EC)
or
0.67 Pt 30%,
40% F1C/i0O
gal
(30%, 40%
FIC)
0.25 lb/100
gal
(25% WP)
or
0.03—0. 13
oz/ gal**
or
0. 61—0. 63
lb/100 gal
(1, 1.63,
1.65 lb/gal
BC)
(12.5%,
12.8%, 20%
EC ) #
or
4—4.5 tbls 5%
Ed gal
or
1.5 gal 5%
EC/lOO gal
(5% EC)
or
2 tbls 10%
EC/gal
or
6 Pt 10% EC/
100 gal
(102 Ed)
or
Bark application. Apply to trunk
and lower branches from crotch to
ground. Soak bark to the point of
runoff. First application should
be made between July 10 and 15 fol—
lowed by 2 subsequent applications
at 21 to 28 day intervals.
For liquid ready—to—use formulation,
pour product into a sprayer bottle
that can be adjusted to deliver a
pin point stream. Inject into feed-
ing entry hole.
For roundheaded appletree borer ,
apply at the beginning of the larval
stage or during the pupal stage at
both of which times the pests are
located just under the bark. Con—
suit your State Agricultural Exten-
sion Service to determine the life
cycle of the borer to be controlled.
For flatheaded appietree borer , ap-
ply as soon as symptoms are first
observed. The symptoms can include
a damp spot on the bark at the point
of early infestation, developing
until the sap drips from the spot;
discoloration of bark overlying the
tunnel; and the possible appearance
of dry feces at the entrance to or
just below the tunnels. If the
Issued: 6—05—84
1 1 1—009001—5
INAHALA
ITBQAHA
INALBNA
INBQBQA
Flatheaded apple—
tree borer
Peachtrèé borer
Roundheaded apple—
tree borer
Shotho].e borer
49
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EPA Index to Pesticide Chemicals
LINDANE (GANNA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosage8 and Tolerance, Use, Limitations
Formulation(s)
Apple (continued)
—— treated areas have not dried within
(1% RTU) 7 to 10 days, treatment should be
repeated.
/O500 IAA Apricot 1 ppm
60 day preharvest interval through
0.62 pound per 100 gallons of water
for bark application.
ITBQAHA Peachtree borer 0.1 oz**/gal Bark application. Apply to trunk
or and lower branches from crotch to
0.62 lb/100 ground. Do not apply to fruit or
gal foliage. Apply in late spring or
(20% EC)# early summer.
/I6002AA Asparagus 1 ppm
Seedling and postcutting stage ap-
plication through 0.5 pound per
acre.
INAMBDA Asparagus beetle 0.35—0.5 lb/A Seedling and postcutting stage ap—
IMOAAAA Thrips (1% D) plication. Dust thoroughly.
/28063AA Barley No tolerance established.
Seed treatment through 1 ounce per
100 pounds of seed for slurry and
dry methods or 2 ounces per bushel
of seed for planter box method.
INAKABA Seedcorn beetle I oz/lO0 lb Seed treatment. Apply by slurry
IOACA}IA Seedcorn maggot seed method. Apply 0.5 pint of liquid
INBPAAA White grubs (25%, 75% WP) slurry per 100 pounds of seed.
INAVAAA Wireworms (75% WP/D)
(2.67, 4 lb/
gal RTU)
or
2 fl.oz 25%
EC, RTU/lOO
lb seed
(25% Ec)
(252 RTU)
or
1.35—4 fl.oz
30% F1C/lO0
lb seed
(30% FtC)
or
Issued: 6—05—84 itI—00900l6
50
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Barley (continued)
1—3 fl.oz 40%
FIC/lOO lb
seed
(40% F1C)
2 oz/bu Seed treatment. Apply by planter
(25% WP/D) box method.
—-OR MAI--
0.81—1 oz/100
lb 8eed
(12.5%, 25%
D)
or
0.375 oz/bu
(18.75% D)
or
3 fl.oz 8.6%,
10.5% RTU/bu
(8.6%, 10.5%
RTU)
I oz/100 lb Seed treatment. Apply by dry meth—
seed od.
(75% WP)
(75% WP/D)
/28001AA Beans No tolerance established.
Seed treatment through 1 ounce per
100 pounds of seed for slurry and
dry methods or 2 ounces per bushel
of seed for planter box method.
INAKABA Seedcorn beetle 0.5—1 oz/lOO Seed treatment. Apply by slurry
IOACAHA Seedcorn laggot lb seed method. Apply 0.5 pint of liquid
INBPAAA White grubs (25%, 75% WP) slurry per 100 pounds of seed.
INAVAAA Wireworins (75% WP/D)
(4 lb/gal
RTU)
or
2 fl.oz 25%
EC, RTU/lO0
lb seed
(25% EC)
(25% RTU)
or
Issued: 6—05—84 IIt—00900l7
51
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EPA Index to Pesticide Chemicals
LINDANE (GANMA ISOMER OF BENZENE HEXACHLORIDE).
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Beans (continued)
0.7—2.67
fl.oz 30%
F1C/l00 lb
seed
(30% FlC)
or
0.5—2 fl.oz
40% F1C/100
lb seed
(40% F1C)
2 oz/bu Seed treatment. Apply by planter
(25% WP/D) box method.
--OR MAI—-
0.5 oz/l00
lb seed
(12.5%, 25%
D)
or
0.42—0.58
oz/bu
(16.6% D)
0.5—1 oz/l0O Seed treatment. Apply by dry metn
lb seed ad.
(75% WP)
/15002AA Beans, Succulent No tolerance established.
Seed treatment through 0.5 ounce per
100 pounds of seed.
INAKABA Seedcorn beetle 0.25—0.5 oz/ Seed treatment. Apply by slurry
IOACAHA Seedcorn maggot 100 lb seed method. Apply 0.5 pint of liquid
INBPAAA White grubs (25%, 75% WP) 8lurry per 100 pounds of seed.
INAVAAA Wireworms (75% WP/D)
(2.67, 4 lb/
gal RTU)
or
I fl.oz 25%
EC, RTU/l00
lb seed
(25% EC)
(25% RTU)
or
Issued: 6—05—84 111—009001—8
52
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Tolerance, Use, Limitations
Formulation(s)
Beans, Succulent (continued)
0.75—1.5
fl.oz 40%
F1C/l00 lb
seed
(40% F1C)
0.25 oz/l00 Seed treatment. Apply by planter
lb seed box method.
(25% D)
0.25—0.5 oz/ Seed treatment. Apply by dry ineth—
100 lb seed od.
(25% wP)
(75% WP/D)
/28002kA Beets No tolerance e8tablished.
Seed treatment through 4 ounces per
100 pounds of seed.
INAKABA Seedcorn beetle 10.8 fl.oz Seed treatment. Apply by slurry
IOACAHA Seedcorn maggot 30% F1C/lOO method.
INBPAAA White grubs lb seed
INAVA.AA Wireworms (30% FIC)
or
8 fl.oz 40%
F1C/l00 lb
seed
(40% F]C)
or
4 oz/lOO lb
seed
(2.67, 4 lb/
gal RTU)
Issued: 6—05—84 111—009001—9
53
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
/ 13005AA
/13006AA
/ 13007AA
/ 13008AA
IRACAAA
ITBCC SA
ITBCCZA
INAMADA
ITBJA}IA,
IMAAACA
IQAQAAA
ITBJAGA
IMOAAAJj,
IOACADA
ITBCABA
INANBIC
INBPAAA
INAVAAA
Site and Pest
Broccoli
Brussels Sprouts
Cabbage
Cauliflower
Aphids
Cabbage looper
Climbing cutworms
Flea beetles
Imported cabbage
worm
Leafuijners (in-
cluding serpen-
tine leafminer)
Plant bugs
Southern cabbage—
worm
Th rips
Cabbage maggot
Cutworcis
Diabrotica beetles
(larvae)
White grubs
Wireworm8
Dosages and
Formulation(s )
0.1—0.4 lb/A
(1% D)
or
0.04 oz**/gal
or
0.25 tsp
actual*/ gal
or
0.2—0.75 lb/A
(6%, 252 WP)
or
0.03 oz**/gal
or
0. 31—0.43
lb/A
(0.36, 1.65,
1.7 lb/gal
EC)
1 lb/A
(252 WP)
0.25—0.5 lb/A
(25% WP)
Tolerance, Use, Limitations
1 ppm
Do not apply after edible parts
start to form through 0.75 pound pax
acre for foliar application.
Soil application through 1 pound per
acre.
Seed treatment through 1.8 ounces
per 100 pounds of seed.
For wettable powder formulation.,
apply in a maximum of 200 gallons
of water per acre.
Foliar application.
Soil application. Apply to soil
around base of plants.
Preplant soil application. Spray
directly on soil, then disc as soon
as practicable to give thorough dis-
tribution in upper 4 to 6 inches of
soil.
INAKABA
IOACAHA
INBPAAA
INAVAAA
Seedcorn beetle
Seedcorn maggot
White grubs
W ireworms
Issued: 6—05—84
0.5 oz/lOO
lb seed
(752 WP)
or
2 fl.oz 252
EC/100 lb
seed
(25% EC)
or
1 1 1—009001—10
Seed treatment. Apply by slurry
method.
54
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF.BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Broccoli (continued)
1.33—4.9
fl.oz 30%
F1C/lOO lb
seed
(30% F1C)
or
1—3.6 fl.oz
40% FIC/100
lb seed
(40% FIC)
or
1.8 oz/100
lb seed
(2.67, 4 lb/
gal RTU)
0.5 oz/100 Seed treatment. Apply by planter
lb seed box method.
(25% n)
/28073U Carrots No tolerance established.
Seed treatment through 1 ounce per
100 pounds of seed.
INAKABA Seedcorn beetle 1 oz/100 Seed treatment. Apply by slurry
IOACAMA Seedcorn maggot lb seed method. Apply 1.3 pints of liquid
INBPAAA White grubs (25%, 75% wP) slurry per 100 pounds of seed.
INAVAAA Wireworms (75% WP/D)
(2.67, 4 lb/
gal RTU)
or
4 fl.oz 25%
EC, RTU/lOO
lb seed
(25% EC)
(25% RTU)
or
2. 67—4. 9
fI.oz 30%
FIC/100 lb
seed
(30% F1C)
or
2—3 fl.oz 40%
FIC/100 lb
seed
(40% F1C)
Issued: 6—05—84 tii—00900111
55
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosa ges and Tolerance, Use, Limitations
Formulation(s)
Carrots (continued)
1 oz/100 lb Seed treatment. May be applied by
seed planter box or dry method.
(75% WP)
(25%, 75%
WP ID)
Cauliflower See Broccoli cluster.
/28003 AA Celery 1 ppm
Do not apply after plants are half
grown or begin to bunch through 0.75
pound per acre for foliar applica-
tion.
Preplant soil application through
2.06 pounds per acre.
For wettable powder formulations,
apply in a maximum of 200 gallons
of water per acre.
IRACAAA Aphids 0.1—0.4 lb/A Foliar application.
ITAAAAA Caterpillars (in— (1% 0)
cluding climbing or
cutworm) 0.25 tsp
ITBMCQC Celery leaftier actual*/gal
(larvae) or
ITBCARC Celery looper 0.3—0.75 lb/A
(larvae) (25% WP)
INAMACA Cucumber beetles or
ITBMCPA False celery leaf— 0.32—0.4 lb/A
tier (1.65, 1.7
INANADA Flea beetles lb/gal EC)
IMAAACA Leafminers
ITBHAFA Pars leyworm
IQAMATA Tarnished plant bug
IMOAAAA Thrips
ITBCABA Cutworms 0.25—1 lb/A Preplant soil application. Spray
INAMBIC Diabrotica beetles (6%, 25% wP) directly on soil, then disc as soon
(larvae) or as practicable to give thorough dis—
INBPAAA White grubs 0.41—0.52 tribution in upper 4 to 6 inches of
INAVAAA Wireworins lb/A soil. For garden symphylan , apply
(1.65 lb/gal the higher dosage for heavy infesta—
EC) tion.
or
0.31 lb/100
gal
(10.68% EC)#
Issued: 6—05—84 111—009001—12
56
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF .BENZENE HEXACHLORIDE)
Site and Pest
Celery (continued)
Dosages and
Formulation(s )
Tolerance, Use, Limitations
IJDAABA
Garden symphylan
1.24—2.06
lb/A
(1.65 lb/gal
EC)
Cherry 1 ppm
Do not apply to foliage or fruit
after fruit starts to form through
1 pound per acre.
Flea beetles
Plum curculio
Thrips
0.3 lb/l00
gal
(1.6 lb/gal
EC)
0.03 oz**/ga].
(20% EC)#
0.25 pt 40%
EC/lO0 gal
(40% EC)
or
0.33 pt 30%,
40% F1C/lOO
gal
(30%, 40%
F lC)
0.03 oz**/gal
(20% EC)#
0.06—0.1
o z**/ gal
or
0.61—0.63
lb/lOU gal
(1.63, 1.65
lb/gal EC)
(12.8%, 20%
EC) #
4—4.5 tbls
52 EC/gal
(52 EC)
Bark application.. Apply to trunk
and lower branches from crotch to
ground. Soak bark to the point of
runoff. First application should
be made between July 10 and 15 fol-
lowed by 2 subsequent applications
at 21 to 28 day intervals.
Issued: 6—05—84
111—009001—13
57
Aphids
Foliar application.
or
/05002AA
I RACAAA
INAMADA
INASAVA
IMOAAAA
INAHALA
ITBQAHA
INALBNA
INBQBQA
or
Flatheaded apple—
tree borer
Peachtree borer
Roundheaded apple—
tree borer
Shothole borer
or
or
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF. SENZENE HEXACHLORIDE)•
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Cherry (continued)
1.5 gal 5%
EC/100 gal
(5% EC)
or
2 tbls 10%
EC /ga I
or
6 pt 10% Ed
100 gal
(10% EC)
Clover See Alfalfa cluster.
/ 13009AA Collards 1 ppm
Do not apply after edible parts
start to form through 0.48 pound per
acre for foliar application.
Preplant soil application through I
pound per acre.
For wettable powder formulations,
apply in a maximum of 200 gallons
of water per acre.
IRACAAA Aphids 0.24 lb/lOU Foliar application.
ITBCCSA Cabbage looper gal
ITBCCZA Climbing cutworms or
INAMADA Flea beetles 0.48 lb/A
ITBJA}IA Imported cabbage— (6% WP)
worm or
IMAAACA Leafmjners (in— 0.21 lb/lOO
cluding serpen— gal
tine leafminer) or
IQAQAAA Plant bugs 0.32 lb/A
ITBJAGA Southern cabbage— (1.65 lb/gal
worm EC)
IMOAAAA Thrips
ITBCABA Cutworms 0.5 lb/lOO Preplant soil application. Work in
INBPAAA White grubs gal to soil thoroughly during or before
INAVAAA Wireworms or planting.
I lb/A
(6% wP)
or
0.31 lb/l00
gal
(10.68% EC)#
Issued: 6—05—84 111—009001—14
58
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EPA Index to Pesticide Chemicals
LINDANE (cAi’1 4A ISOMER OF .BENZENE HEXACULORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/28006EA Corn No tolerance established.
Seed treatment through 2 ounces per
100 pounds or per bushel of seed.
INAKABA Seedcorn beetle 1—2 oz/l0O Seed treatment. Apply by slurry
IOACAHA Seedcorn maggot lb seed method. Apply 0.5 pint of liquid
INBPAAA White grubs (25%, 75% WP) slurry per 100 pounds of seed.
INAVAAA Wireworms (75% WP/D)
(2.67, 4 lb/
gal RTU)
or
4 fl.oz 25%
EC, RTU/l00
lb seed
(25% EC)
(25% RTU)
or
3.33—6.67
fl.oz 30%
F1C/100 lb
seed
(302 F1C)
or
2.5—5 fl.oz
40% F1C/l0O
lb seed
(40% F1C)
1—2 oz/lO0 Seed treatment. Apply by planter
lb seed box method.
(25% D)
(25% WP)
(75% WP/D)
or
1—2 oz/bu
(12.5%, 25%
D)
(25% WP)
(25% WP/D)
—-OR MAI-—
0.42—1 oz/bu
(12.5%,
16 • 6%,
18.75% D)
or
Issued: 6—05—84 1 11 009 0 0145
59
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest
Corn (continued)
and
Formulation(s )
Tolerance, Use, Limitations
4 fl,oz 8.6%
RTU/bu
(8.62 RTU)
or
5.5 fl.oz
10.52 RTU/bu
(10.5% RTU)
INAKABA
ZOACAHA
INBPAAA
INAVAAA
Seedcorn beetle
Seedcorn maggot
White grubs
Wireworms
2 oz/100 lb
seed
(75% WP/D)
1—2 oz/lOO
lb seed
(25%, 752 WP)
(752 WP/D)
(2.67, 4 lb/
gal RTU)
or
6.4 fl.oz 252
EC, RTU/100
lb seed
(252 EC)
(25% RTU)
or
5—6.67 fl.oz
30% FIC/I00
lb seed
(30% PlC)
or
3.75—5 fl.oz
402 F1C/l00
lb seed
(40% PlC)
2.25 oz/l00
lb seed
(25% WP)
(75% WP/D)
(4 lb/gal
PlC)
or
Seed treatment.
od.
/28007u tton
Apply by dry meth—
No tolerance established.
Seed treatment through 2.25 ounces
per 100 pounds of 8eed.
Seed treatment. Apply by slurry
method to delinted, refined and acid
cottonseed. Apply 1 pint of liquid
slurry per 100 pounds of seed.
Seed treatment. Apply by slurry
method to fuzzy, undelinted cotton-
seed. Apply 1 pint of liquid slurry
per 100 pounds of seed.
Issued: 6—05—84
1 11—009001—16
60
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE BEXACHLORIDE)
Site and Pest j j and Tolerance, Use, Limitations
Formulation(s)
Cotton (continued)
7.2 fl.oz 25%
EC, RTU/lOO
lb seed
(25% EC)
(25% RTU)
or
6—8 fl.oz 30%
F1C/lOO lb
seed
(30% F1C)
or
4—6 fl.oz 40%
F IC/ 100 lb
seed
(40% PlC)
2 oz/lOO lb Seed treatment. Apply by planter
seed box method to delinted, refined and
or acid—treated cottonseed.
2 oz/bu
(25% WP/D)
2.25 oz/lO0 Seed treatment. Apply by planter
lb seed box method to fuzzy, undelinted
(25% D) cottonseed.
2 oz/lO0 lb Seed treatment. Apply by dry meth—
seed od to delinted, refined and acid—
(75% WP/D) treated cottonseed.
2.25 oz/].O0 Seed treatment. Apply by dry ineth—
lb seed od to fuzzy, undelinted cottonseed.
(75% WP/D)
Issued 6—05—84 111—009001—17
61
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PA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF.BENZENE HEXACIILORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/1001OAA Cucumber 3 ppm
/ I000 1AA I day preharvest interval through
/ IOO I IAA 0.63 pound per acre.
/1 00 12AA Preplant soil application through
2.06 pounds per acre.
Seed treatment through 1.8 ounces
per 100 pounds of seed.
Do not apply after blossoms open.
For wettable powder formulations,
apply in a maximum of 200 gallons
of water per acre.
IRACAAA Aphids 0.1—0.5 lb/A Foliar application. Apply when
ITBCCZA Climbing cutworms (0.75%, 1% D) plants first break through the
INAMACA Cucumber beetles or ground or when plants are about 1
(including spotted 0.25 tsp inch in height. Repeat as needed.
cucumber beetle actual*/gal For cucumber beetles and thrips ,
and striped cucuin— or apply the lower dosage of the range.
ber beetle) 0.2—0.63 lb/A For melonworm and pickleworm , apply
IVABAAA Grasshoppers (10%, 25% WP) when worms are first seen in the
IMAAAGA Leafminers or blossoms and repeat at 7 day inter—
IQAMARA Lygus bugs 0.25 tbls vals or as needed. For squash vine
ITBMAUA l4elonworm actual*/gal borer , thoroughly cover stems and
ITBMAWA Pickleworm (252 WP/D) vines at the base of plants.
IQAQAAA Plant bugs or Dust formulations may be formulated
IQAGAFA Squash bug 0.03 oz**/gal with maneb.
ITBQADA Squash vine borer or
IMOAAAA Thrips 0.2—0.41 lb/A
(0.36, 1.6
lb/gal EC)
ITBCABA Cutworms 0.25—1 lb/A Preplant soil application. Spray
INAMBIC Diabrotica beetles (6%, 25% WP) directly on soil, then disc as soon
(larvae) or as practicable to give thorough dis—
INBPA.AA White grubs 0.41—0.52 tribution in upper 4 to 6 inches of
INAVAA.A Wireworms lb/A soil. For garden symphylan , apply
(1.65 lb/gal the higher dosage for heavy infesta—
EC) tion.
or
0.31 lb/lOO
gal
(10.68% EC)#
IJDAABA Garden symphylan 1.24—2.06
lb/A
(1.65 lb/gal
EC)
Issued: 6—05—84 111—009001—18
62
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF. BENZENE REXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Cucumber (continued)
INAKABA Seedcorn beetle I oz/l0O lb Seed treatment. Apply by slurry
IOACAHA Seedcorn maggot seed method. Apply 0.5 pint of liquid
INBPAAA White grubs (25%, 752 WP) slurry per 100 pounds of seed.
INAVAAA Wireworms (75% W?/D)
or
4 fl.oz 25%
EC, RTU/l00
lb seed
(25% EC)
(25% RTU)
or
2.67—4.9
fl.oz 30%
F IC/100 lb
seed
(30% FIC)
or
2—3.6 fl.oz
40% FIC/lO0
lb seed
(40% FIC)
or
1.8 oz/lOO
lb seed
(2.67, 4 lb/
gal RTU)
]. oz/l00 lb Seed treatment. May be applied by
seed planter box or dry method.
(252 D)
(75% Wi ’)
(25%, 75%
Wi’ ID)
/ 11 0 0 IAA Eggplant 1 ppm
Do not apply after edible parts
start to form through 0.45 pound per
acre.
IRACAAA Aphids 0.1—0.45 lb/A Foliar application.
ITBCCZA Climbing cutworms (1% D)
INAMADA Flea beetles or
IQAXAAA Lace bugs 0.03 oz**/gal.
IMAAACA Leafminers (0.36 lb/gal
IQAQAAA Plant bugs EC)
IQAGAFA Squash bug or
ITBQADA Squash vine borer
IMOAAAA Thrips
Issued: 6—05—84 1 11—009001—19
63
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF. BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Eggplant (continued)
0.43 lb/A
(1.7 lb/gal
EC)
/28009AA Flax No tolerance established.
Seed treatment through 2 ounces per
100 pounds of seed.
INAKABA Seedcorn beetle 1.5 oz/100 Seed treatment. Apply by slurry
LOACAHA Seedcorn maggot lb seed method.
INBPAAA White grubs (75Z WE’)
INAVAAA Wirevorme or
2 fl.oz 25%
EC, RTU/100
lb seed
(25% EC)
(25% RTU)
or
1.33—2 fl.oz
30% F1C/lO0
lb seed
(30% FIC)
or
1—1.5 fl.oz
40% F1C/lOO
lb seed
(40% F1C)
2 oz/l00 lb Seed treatment. Apply by planter
seed box method.
(25% WP/D)
—-OR MAI—
0.5 oz/IOO lb
seed
(25% D)
or
0.75 oz/bu
(18.75% D)
or
8 fl.oz 10.52
RTU/bu
(10.5% RTU)
r1I_00900120
tasued: 6—05—84 64
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF.BENZENE HEXACHLOR IDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/O IO14AA Grapes 1 ppm
Do not apply later than 1 month af-
ter bloom through 1 quart of 40 per-
cent emulsifiable concentrate formu-
lation; and 30 and 40 percent of
flowable concentrate formulation per
acre.
IR.AVAJA Grape phylloxera 1 qt 40% EC, Foliar application. Apply in suff i—
302 and 402 dent water for thorough coverage.
F1C/A
(40% EC)
(30%, 40%
F 1C)
/13 00 1AA Kale 1 ppm
Do not apply after edible parts
start to form through 0.43 pound per
acre for foliar application.
Preplant soil application through
2.06 pounds per acre.
IRACAAA Aphids 0.41—0.43 Foliar application.
ITBCCSA Cabbage looper lb/A
ITBCCZA Climbing cutworins (1.65, 1.7
INAMADA Flea beetles lb/gal EC)
ITBJAHA Imported cabbage—
worm
IMAAAGA Leafminers (in-
cluding serpen-
tine leafminer)
IQAQAAA Plant bugs
ITSJAGA Southern cabbage—
worm
IMOAAAA Thrips
ITBCASA Cutworms 0.25—0.5 lb/A Preplant soil application. Spray
INAMBIC Diabrotica beetles (25% WP) directly on soil, then disc as soon
(larvae) or as practicable to give thorough dis—
UIBPAAA White grubs 0.41—0.52 tribution in upper 4 to 6 inches of
INAVAAA Wireworms lb/A soil. For garden symphylan , apply
(1.65/gal the higher dosage for heavy infesta—
EC) tion.
IJDAABA Garden symphylan 1.24—2.06
lb/A
(1.65 lb/gal
EC)
Issued: 6—05—84 111—009001—21
65
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF.BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/ I SO 1IAA Lentils No tolerance established.
Seed treatment through 1 ounce per
100 pounds of seed.
INAKABA Seedcorn beetle 0.94—1 oz/lOO Seed treatment. Apply by slurry
LOACAHA Seedcorn maggot lb seed method.
INBPAAA White grubs (75% wP)
INAVAAA Wirevorms (2.67, 4 lb/
gal RTU)
or
3.2 fl.oz 25%
EC, RTU/l00
lb seed
(25% EC)
(25% RTU)
or
2.7—3.33
fl.oz 30%
F1C/100 lb
seed
(30% F1C)
or
1. 75—2.5
fl.oz 40%
F1C/100 lb
seed
(40% F1C)
0.94 oz/lOO Seed treatment. Apply by dry meth—
lb seed od.
(75% WP)
/13020AA Lettuce 3 ppm
Do not apply to leaf lettuce after
seedling stage or to head lettuce
after the heads begin to form
through 0.43 pound per acre.
Preplant soil application through
2.06 pounds per acre.
Seed treatment through 1 ounce per
100 pounds of seed.
IRACAAA Aphids 0.3—0.4 lb/A Foliar application.
ITBCABA Cutworms (1% o)
INANADA Flea beetles or
INAAAGA Leafminers 2 tbls
II4 OAAAA Thrips actual*/ga l
ITAAAMA Webworms (25% WP/D)
or
Issued: 6—05—84 III—00900122
66
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF. BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Lettuce (continued)
0.43 lb/A
(1.7 lb/gal
EC)
ITBCABA Cutwornis 0.25—1 lb/A Preplant soil application. Spray
INAMBIC Diabrotica beetles (6%, 25% WP) directly on soil, then disc as soon
(larvae) or as practicable to give thorough dis—
INBPAAA White grubs 0.41—0.52 trubtion in upper 4 to 6 inches of
INAVAAA Wireworms lb/A soil. For garden symphylan , apply
(1.65 lb/gal the higher dosage for heavy infesta—
EC) tion.
or
0.31 lb/100
gal
(10.68% EC)#
IJDAABA Garden symphylan 1.24—2.06
lb/A
(1.65 lb/gal
EC)
INAKABA Seedcorn beetle 1 oz/100 lb Seed treatment. Apply by slurry
IOACAHA Seedcorn maggot seed method. Apply 1.3 pints of liquid
[ NBPAAA White grubs (25%, 75% WP) slurry per 100 pounds of seed.
INAVAAA Wireworms (75% WP/D)
or
4 fl.oz 25%
EC, RTU/ 100
lb seed
(25% EC)
(25% RTU)
or
2.6 7—3.33
fl.oz 30%
F1C/100 lb
seed
(30% FIC)
or
2—2.5 fl.oz
40% F1C/lOO
lb seed
(40% F1C)
I8sued: 6—05—84 111—009001—23
67
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EPA Index to Pesticide Chemicals
LINDANE (cAloIA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest
Lettuce (continued)
Dosages and
Forinulation( 5 )
Tolerance, Use, Limitations
/1 000 1AA
1 oz/lOO lb
seed
(25% D)
(75% WP)
(25%, 75%
WP/D)
Melons (including Cantaloupe and
Watermelon)
Seed treatment. May be applied by
planter box or dry method.
3 ppm
Do not apply after blossoms open
through 0.5 pound per acre for foli—
ar application.
Preplant soil application through
2.06 pounds per acre.
Seed treatment through 1.8 ounces
per 100 pounds of seed.
Late foliar treatment may result in
reduction of quality at harvest.
For wettable powder formulations,
apply in a maximum of 200 gallons
of water per acre.
Preplant soil application. Spray
directly on soil, then disc as soon
as practicable to give thorough di&—
tribution in upper 4 to 6 inches of
soil.
Refer to Cucumber for additional information.
/28062AA
Oats
No tolerance established.
Seed treatment through 0.5 ounce per
100 pounds of seed for slurry and
dry methods or 2 ounces per bushel
of seed for planter box method.
INAKABA
IOACAHA
INBPAAA
INAVAAA
Seedcorn beetle
Seedcorn maggot
White grubs
Wireworuas
Issued: 6—05—84
0.5 oz/lOO lb
seed
(25%, 75% WP)
(75% wP/D)
(2.67, 4 lb/
gal RTU)
1 11—009001—24
68
ITBCABA
Cutworms
0.03—0.04
INANBIC
Diabrotica beetles oz**/gal
(larvae) [ 0.8 gall
INBPAAA
White grubs
100 sq.ftj
INAVAAA
WireworTfl8
(12.5%, 20%
EC )#
Seed treatment. Apply by slurry
method. Apply 05 pint of liquid
slurry per 100 pounds of seed.
or
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF .BENZENE HEXACHLORIDE)
Site and Peat Tolerance, Use, Limitations
Formulation(s)
Oats (continued)
1.6 fl.oz 25%
EC, RTU/100
lb seed
(25% EC)
(25% RTU)
or
1.33—2 fl.oa
30% FIC/lO0
lb seed
(30% PlC)
or
1—1.5 fl.oz
40% FIC/l00
lb seed
(40% F1C)
2 oz/bu Seed treatment. Apply by planter
(25% WP/D) box method.
--OR MAt--
0.5—0.81. oz/
100 lb seed
(12.5%, 25%
D)
or
0.375 oz/bu
(18.75% D)
or
3 fl.oa 8.6%,
10.5% RTLI/
bu
(8.6%, 10.5%
RTU)
0.5 oz/lOO lb Seed treatment. Apply by dry meth—
seed od.
(752 WP/D)
Issued: 6—05—84 111—009001—25
69
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Foruiulat ion(s )
/150 15AA Okra I ppm
Preplant soil application through 1
pound per acre.
Seed treatment through 1 ounce per
100 pounds of seed.
ITBCAEA Cutworms 0.5 Lb/ 100 Preplant soil application. Work in—
INBPAA.A White grubs gal to soil thoroughly during or before
INAVAAA Wireworins or planting.
l lb/A
(6% wP)
or
0.3 lb/100
gal
(10.68% EC)#
or
0.03—0. 04
oz**/gal
[ 0.8 gall
100 sq.ftl
(12.5%, 20%
EC ) #
INAKABA Seedcorn beetle I oz/lO0 lb Seed treatment. Apply by slurry
IOACAHA Seedcorn maggot seed method. Apply 0.5 pint of liquid
INBPAAA White grubs (25%, 75% wP) slurry per 100 pounds of seed.
INAVAAA Wirewonna (75% WP/D)
or
4 fl.oz 25%
EC, RTU/100
lb seed
(25% BC)
(25% RTU)
or
2.67—4 fl.oz
30% F1C/100
lb seed
(30% F1C)
or
2—3 fl.oz 40%
F1C/100 lb
seed
(40% PlC)
1 oa/100 lb Seed treatment. May be applied by
seed planter box or dry method.
(25% D)
(25% 75%
WP/D)
Issued: 6—0584 III—00900 126
70
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF•BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance Use, Limitations
Formulation(s )
/14O 11AA Onion, Dry 1 ppm (dry bulb only)
Foliar application through 0.85
pound per acre.
Soil application through 1 pound per
acre.
Seed treatment through 1 ounce per
100 pounds of seed.
For wettable powder formulations,
apply in 100 to 200 gallons of water
per acre.
ZOACACA Onion maggot 1 lb/A Soil application. Apply as a pre—
(25% Wi ’) plant or at planting time treatment,
or when plants are 2 to 3 inches
tall.
IMOAAAA Thrips 0.1—0.65 lb/A Foliar application. Apply when pest
(1% D) count average 5 to 6 per plant. Re—
or peat in 5 to 6 days. A third appli—
0.25—0.5 lb/A cation may be needed.
(25% Wi’)
or
0.85 lb/A
(1.7 lb/gal
EC)
INAKABA Seedcorn beetle 0.75—1 oz/l00 Seed treatment. Apply by slurry
IOACAHA Seedcorn maggot lb seed method.
INBPAAA White grubs (25%, 75°!. Wi’)
INAVAAA Wireworma (2.67, 4 lb/
gal RTU)
or
4 fl.oz 25%
EC, RTU/100
lb seed
(25% EC)
(25% RTU)
or
2.67—4 fl.oz
30% F1C/100
lb seed
(30% FIC)
or
2—3 fl.oz 40%
FIC/iCO lb
seed
(40% F1C)
Iseued: 6—05—84 111—009001—27
71
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENIENE IIEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Onion, Dry (continued)
1. oz/100 lb Seed treatment. Apply by planter
seed box method.
(25% D)
(25% WP/D)
/05004AA Peach 1 ppm
60 day preharvest interval through
0.65 pound per acre for foliar ap-
plication or through 0.63 pound per
100 gallons of water for bark appli-
cation.
Do not apply later than 7 days after
shuck split.
IRAGMA Aphids 0.35—0.65 Foliar application.
IMAAAEA Leafrollers lb/A
INASAVA Plum curculio (1% D)
IMOMAA Thrips or
0.24—0.31
lb/l00 gal
(6% WP)
(10.68% EC)#
or
0,03 oz**/gal
(20% EC)#
INAHALA Flatheaded apple— 0.03—0.1 Bark application. Apply to trunk
tree borer oz**/ga l and lower branches from crotch to
ITBQAHA Peachtree borer or ground. Soak bark to the point of
INALBNA Roundheaded apple— 0.61—0.63 runoff. First application should
tree borer lb/100 gal be made between July 10 and 15 fol—
INBQBQA Shothole borer (1.63, 1.65 lowed by 2 subsequent applications
EC) at 21 to 28 day intervals.
(12.5%,
12.8%, 20%
EC ) #
or
4—4.5 tbls
5% EC/gal
or
1.5 gal 5%
ECI100 gal
(5% EC)
or
2 tbla 10%
Ed gal
(10% EC)
or
Issued: 6—05—84 III—00900128
72
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE MEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Peach (continued)
6 Pt 10% Ed
100 gal
(10% EC)
/040 03AA Pear 1 ppm
60 day preharvest interval through
0.65 pound per acre.
IRACAAA Aphids 0.5 pt 40% Foliar application.
EC/l00 gal
(40% EC)
or
0.67 Pt 302,
40% F1C/lOO
gal
(302 FiG)
(40% F1C)
INAMADA Flea beetles 0.03 oz**/gal
INASAVA Plum curculio (20%EC)#
IMOAAAA Thrips
IRAXALA Pear psylla 0.35—0.65
lb/A
(1% D)
INAHALA Flatheaded apple— —— Bark application. Apply to trunk
tree borer (1% RTU) and lower brartche8 from crotch to
ENALBNA Roundheaded apple- ground. Soak bark to the point of
tree borer runoff. First application should
be made between July 10 and 15 fol—
loved by 2 subsequent applications
at 21 to 28 day intervals.
Pour product into a sprayer bottle
that can be adjusted to deliver a
pin point stream. Inject into feed-
ing entry hole.
For roundheaded appletree borer ,
apply at the beginning of the larval
stage or during the pupal stage at
both of which times the pests are
located just under the bark. Con-
sult your State Agricultural Exten-
sion Service to determine the life
cycle of the borer to be controlled.
For flatheaded appletree borer , ap-
ply as soon as symptoms are first
observed.
Issued: 6—05—84 111—009001—29
73
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EPA Index to Pesticide Chemicals
LINDANE (GANMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Pear (continued)
The symptoms can include a damp spot
on the bark at the point of early
infestation, developing until the
sap drips from the spot; discolora-
tion of bark overlying the tunnel;
and the possible appearance of dry
feces at the entrance to or just
below the tunnels. If the treated
areas have not dried within 7 to 10
days, treatment should be repeated.
/28016AA Peas (including Cowpeas) No tolerance establi8hed.
Seed treatment through 1 ounce per
100 pounds of seed for slurry and
dry methods or 2 ounces per bushel
of seed for planter box method.
INAXABA Seedcorn beetle 0.75—1 oz/lOO Seed treatment. Apply by slurry
IOACAHA Seedcorn maggot lb seed method. Apply 0.5 pint of liquid
INBPAAA White grubs (25%, 75% WP) slurry per 100 pounds of seed.
INAVAAA Wireworins (75% WP/D)
(2.67, 4 lb/
gal RTU)
or
3.2 fl.oz 25%
EC, RTU/100
lb seed
(25% EC)
(25% RTU)
or
2.67—3.33
fl.oz 30%
F1C/100 lb
seed
(30% F1C)
or
2—3 fl.oz
40% F1C/lOO
lb seed
(40% F1C)
2 oz/bu Seed treatment. Apply by planter
(25% D) box method.
(25% WP/D)
--OR MAt--
Issued: 6—05—84 111—009001—30
74
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE).
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Peas (continued)
0.42—0.58
oz/bu
(16.6% D)
or
]. oz/l00 lb
seed
(25% D)
1 oz/lOO lb Seed treatment. Apply by dry ineth—
seed od.
(75% WP)
(75% WP/D)
/03008AA Pecan 0.01 ppm
6.5 to 7.5 month preharvest interval
through 1.89 pound per acre for
foliar application.
RESTRICTED USE PESTICIDE.
Do not make more than I application.
Do not apply more than 450 gallons
of water per acre. Do not allow
animals to graze on treated areas.
Do not apply by aircraft.
IUVAHA Pecan phylloxera 0.37—0.42 Foliar application. Apply thorough—
IZZZDGA Shoot curculio lb/lO0 gal ly using airblast sprayer when buds
[ 30 gallons/ are beginning to burst (early to
tree) mid—April). This control is not
(1, 1.63, effective when typical gall symptoms
1.65 lb/gal appear.
Ec)
(20% EC)#
Issued: 6—05—84 111—009001—31
75
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE IIEXACHLORIDE)
Site and Pest Dosages and Tolerance Uee Limitations
Formulation(s )
/28017AA Peppers 1 ppm
Do not apply after edible parts
start to form through 0.75 pound per
acre for foliar application.
Preplant soil application through 1
pound per acre.
For wettable powder formulations,
apply in 100 to 200 gallons of water
per acre.
IRACAAA Aphids 0.1—0.4 lb/A Foliar application. For armyworm ,
ITBCCFA Armyworm (1% D) apply the higher dosage.
ITBCCZA Climbing cutworms or
INAMACA Cucumber beetles 0.25 tsp
INAMADA Flea beetles actual*/gal
IMAAACA Leafminers (in— or
cluding serpen— 0.25 lb/ba
tine leafininer) gal
IMOAAAA Thrips or
0.5—0.75 lb/A
(25% WP)
or
0.32 lb/A
(1.7 lb/gal
Ec)
ITBCABA Cutworma 0.5 lb/bOO Preplant soil application. Work in
INBPAAA White grubs gal to soil thoroughly during or before
INAVAAA Wireworms or planting.
1 lb/A
(6% wP)
or
0.31 lb/bOO
gal
(10.682 EC)#
or
0.03—0.04
oz**/ga l
[ 0.8 gal/l00
sq. ftl
(12.5%, 20%
sc) #
/O6 O13AA Pineapple 1 ppm
This use only occurs on intrastate
and special local needs [ 24(c) ]
labeling and has not been included
in this entry. Refer to appropri-
ate labeling for use information
and limitations.
Issued: 6—05—84 1 1 100900 132
76
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF .BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/05005U Plum I ppm (plums, fresh prunes)
60 day preharveat interval through
1.56 pounds per acre for foliar ap-
plication or through 0.62 pound per
100 gallons of water for bark appli-
cation.
IRACAAA Aphids 0.31 Lb/l0O Foliar application.
IMAAAEA Leafrollers gal
INASAVA Plum curculio or
LMOAAAA Thrips 1.56 lb/A
(10.68% EC)#
or
0.03 oz**/gal
(20% Ec)#
ITBQAHA Peachtree borer 0.1 oZ**/gal Bark application. Apply to trunk
or and lower branches from crotch to
0.62 lb/lOO ground. Soak bark to the point of
gal runoff. First application should
(20% EC)# be made between July 10 and 15 fol-
lowed by 2 subsequent applications
at 21. to 28 day intervals.
Refer to Prune for additional information.
/05006AA Prune 1 ppm
/05005AA 60 day preharvest interval through
0.65 pound per acre for foliar ap—
pli tion.
IRACAAA Aphids 0.35—0.65 Foliar application.
lb/A
(1% D)
or
0.5 pt 40%
EC/lOO gal
(40% EC)
or
0.67 pt 30%,
402 FIC/lOO
gal
(30%, 40%
F1C)
Issued: 6—05—84 111—009001—33
77
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE REXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/100 I IAA Pumpkin 3 ppm
No preharvest interval through 0.5
pound per acre.
Preplant soil application through
2.06 pounds per acre.
Seed treatment through 1 ounce per
100 pounds of seed.
Do not apply after blossoms open.
For wettable powder formulations,
apply in a maximum of 200 gallons
of water per acre.
Refer to Cucumber for additional information.
/14 O 14AA Radish No tolerance established.
Seed treatment through 0.5 ounce per
100 pounds of seed.
INAKABA Seedcorn beetle 0.5 oz/lOO Seed treatment. Apply by slurry
I OACAHA Seedcorn maggot lb seed method.
INBPAAA White grubs (75% WP)
INAVAAA Wireworzns (2.67, 4 lb/
gal RTU)
or
2 fl.oz 25%
EC, RTU/lOO
lb seed
(25% EC)
(25% RTU)
or
1.33—2 fl.oz
30% PlC! 100
lb seed
(30% PlC)
or
1—1.5 fl.oz
40% F1C/l0O
lb seed
(40% F1C)
0.5 oz/lOO Seed treatment. Apply by planter
lb seed box method,
(25% D)
(25% WP/D)
Issued: 6—05—84 1 1F00900134
78
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EPA Index to Pesticide Chemicals
LINDANE (GMIA ISOMER OF.BENZENE REXACHL.ORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/28071AA No tolerance established.
Seed treatment through 0.5 ounce per
100 pounds of seed.
INAKABA Seedcorn beetle 0.5 oz/l00 Seed treatment. Apply by slurry
IOACAHA Seedcorn maggot lb seed method. Apply 0.5 pint of liquid
INBPAAA White grubs (25% 75% WP) slurry per 100 pounds of seed.
IUVAAA Wireworms (75% WP/D)
(2.67, 4 lb/
gal RTU)
or
1 fl.oz 25%
EC, RTU/lOO
lb seed
(25% EC)
(25% RTU)
or
1.33—2.67
fl.oz 30%
F1C/l00 lb
seed
(30% Plc)
or
1—1.25 fl.oz
40% F1C/100
lb seed
(40% FiC)
0.375 oz/bu Seed treatment. Apply by planter
(18.752 D) box method.
or
0.5 oz/100
• lb seed
(25% D)
0.5 oz/100 Seed treatment. Apply by dry meth—
lb seed od.
(75% WP/D)
Issued: 6—05—84 111—009001—35
79
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EPA Index to Pesticide Chemical.
LINDANE (GAMMA ISOMER OF .BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/28076AA Safflower No tolerance established.
Seed treatment through 1.5 ounces
per 100 pounds of seed for slurry
method or through 2 ounces per bush-
el of seed for planter box method.
INAKABA Seedcorn beetle 0.5—1.5 oz/ Seed treatment. Apply by slurry
LOACAHA Seedcorn maggot ioo lb seed method. Apply 0.5 pint of liquid
INBPAAA White grubs (25%, 75% WP) slurry per 100 pounds of seed.
INAVAAA Wireworms (75% WP/D)
(2.67, 4 lb/
gal RTU)
or
1.6 fl.oz 25%
EC, RTU/l00
lb seed
(25% EC)
(25% RTU)
or
1.33—2.67
fl.oz 30%
F1C/100 lb
seed
(30% F1C)
or
1—1.25 fl.oz
40% F1C/100
lb seed
(40% F1C)
2 oz/bu Seed treatment. Apply by planter
(25% WP/D) box method.
--OR MAt—-
0.5 oz/lO0
lb seed
(25% D)
0.75 oz/I.OO Seed treatment. Apply by dry meth—
lb seed od.
(75% WP/D)
Issued: 6—05—84 111—009001—36
80
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF.BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/28019AA Sorghum (including Milo Sorghum) No tolerance established.
Seed treatment through 1.25 ounces
per 100 pounds of seed for slurry
and dry methods or 2 ounces per
bushel of seed for planter box nieth—
od.
INAKABA Seedcorn beetle 1—1.25 oz/100 Seed treatment. Apply by slurry
IOACAFLA Seedeorn maggot lb seed method. Apply 1 pint of liquid
INBPAAA White grubs (25%, 75% WP) slurry per 100 pounds of seed.
LNAVAAA Wireworms (75% WP/D)
or
0.5 oz/lOO
lb seed
(2.67 lb/gal
RTU)
or
4 fl.oz 25%
EC, RTU/l00
lb seed
(25% EC)
(25% RTU)
or
2.67—4 fl.oz
30% F1C/l00
lb seed
(30% F1C)
or
2—3 fl.oz 40%
F1C/100 lb
seed
(40% FIC)
2 oz/bu Seed treatment. Apply by planter
(25% D) box method.
--OR MAI-—
0.42—0.58
oz/bu
(16.6% D)
or
1 oz/l00 lb
seed
(25% D)
Issued: 6—05—84 III0 0900137
81
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EPA Index to Pesticide Chemicals
LINDANE (GA iA ISOMER OF.BENZENE HEXACHLORIDE).
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Sorghum (including Milo Sorghum) (continued)
1—1.25 oz/l00 Seed treatment. Apply by dry meth—
lb seed od.
(75% WP)
(75% !P/D)
/28023AA Soybeans No tolerance established.
Seed treatment through 2 ounces per
bushel of seed.
INAKABA Seedeorn beetle 0.5 oz/100 Seed treatment. Apply by slurry
IOACAHA Seedcorn maggot lb seed method. Apply 0.5 pint of liquid
INBPAAA White grubs (25%, 75% WP) slurry per 100 pounds of seed.
INAVAAA Wireworins (75% WP/D)
or
2 fl.oz 25¼
EC, RTIJ/lOO
lb seed
(25% EC)
(25% RTU)
or
1.33—2 fl.oz
30% F1C/l00
lb seed
(30% F1C)
or
1—1.5 fl.oz
40% F1C/l0O
lb seed
(40% F1C)
2 oz/bu Seed treatment. Apply by planter
(25% WP/D) box method.
-—OR HAl—-
0.42—0.58
oz/bu
(12.5%,
16.6%,
18.75% D)
or
0.5 oz/lOO
lb seed
(25% D)
or
Issued: 6—05—84 111—009001—38
82
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EPA Index to Pesticide Chemicals
LINDANE (CAIIMA ISOMER OFBENZENE HEXACHLORIDE)
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Soybeans (continued)
4 fl.oz 8.6%
RTU/bu
(8.6% RTU)
or
5.5 fl.oz
10.5% RTU/bu
(10.5% RTU)
0.5 oz/lOO
lb seed
(75% WP/D)
Seed treatment.
od.
Apply by dry ineth—
/ 13024AA
Spinach
lppm
Do not apply after seedling stage
through 0.75 pound per acre.
Preplant soil application through
2.06 pounds per acre.
Seed treatment through 1 ounce per
100 pounds of seed.
For wettable powder formulations,
apply in a maximum of 200 gallons
of water per acre.
IRACAAA
ITBCABA
INANADA
IMAAACA
IMOAAAA
ITAAAMA
Aphids
Cutworms
Flea beetles
Leafminers
Tb rips
Webworms
0.1—0.4 lb/A
(1% D)
or
0.25 tsp
actual*/gal
or
0.38—0.75
lb/A
(25% WP)
0.42—0.43
lb/A
(1.65, 1.7
lb/gal EC)
0.25—0.5 lb/A
(25% WP)
or
0.41—0.52
lb/A
(1.65 lb/gal
EC)
Preplant soil application. Spray
directly on soil, then disc as soon
as practicable to give thorough dis
tribution in upper 4 to 6 inches of
soil. For garden symphylan , apply
the higher dosage for heavy infeata
tion.
Issued: 6—05—84
111—009001—39
Foliar application.
or
IT BCABA
INAMB IC
INBPAAA
INAVAAA
Cu two rnts
Diabrotica beetles
(larvae)
White grubs
Wireworms
83
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF.BENZENE HEXACILLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Spinach (continued)
IJDAAP,A Garden symphylan 1.24—2.06
lb/A
(1.65 lbJgal
EC)
INAKABA Seedcorn beetle 0.75—1 oz/100 Seed treatment. Apply by slurry
LOACAHA Seedcorn maggot lb seed method. Apply 1 pint of liquid
INBPAAA White grubs (25%, 75% Wi ’) slurry per 100 pounds of seed.
[ NAVAAA Wirewornis (75% WP/D)
or
4 fl.oz 25%
EC, RTUIIOO
lb seed
(25% EC)
(25% RTU)
or
2.67—4 fl.oz
30% F1C/100
lb seed
(30% F1C)
or
2—3 fl.oz 40%
F1C/100 lb
seed
(402 FLC)
1 oz/l00 lb Seed treatment. May be applied by
seed planter box or dry method.
(25% D)
(25%, 75%
WP/D)
/100 I2AA Squash 3 Ppm
1 day preharvest interval through
0.5 pound per acre.
Preplant soil application through
2.06 pounds per acre.
Seed treatment through 1.8 ounces
per 100 pounds of seed.
Late foliar treatment may result in
reduction of quality at harvest.
For wettable powder formulations,
apply in a maximum of 200 gallons
of water per acre.
Refer to Cucumber for additional information.
Issued: 6—05—84 111—009001—40
84
-------
EPA Index to Pe8ticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/O IO 16AA Strawberry 1 ppm
Do not apply after fruit start8 to
form through 0.15 pound per acre.
Soil application through 0.5 pound
per acre.
ITBCABA Cutworms 0.25—0.5 lb/A Preplant soil application. Spray
INAMBIC Diabrotica beetles (25% WP) directly on soil, then disc as soon
(larvae) as practicable to give thorough dis—
INBPAAA White grubs tribution in upper 4 to 6 inches of
INAVA.AA Wireworms soil.
IRAEAAA Spittlebugs (in— 0.13—0.15 Foliar application. Apply in the
cluding meadow lb/A spring when first leaves appear.
spittlebug) (0.5%, 1% D) Repeat at 5 to 10 day intervals.
INASAAA Weevils (includ— (25% Wi ’) For strawberry weevil , thoroughly
ing strawberry treat the flower buds.
weevil)
/22O 1 1AA Sudangrass No tolerance established.
Seed treatment through 0.5 ounce per
100 pounds of seed.
INAKABA Seedcorn beetle 0.375—0.5 Seed treatment. Apply by slurry
IOACAHA Seedcorn maggot oz/100 lb method. Apply 1.2 pints of liquid
INBPAAA White grubs seed slurry per 100 pounds of seed.
INAVAAA Wireworms (25%, 75% Wi’)
(75% WP/D)
(2.67, 4 lb/
gal RTU)
or
1.6 fl.oz 25%
EC, RTU/l0O
lb seed
(25% EC)
(25% RTU)
or
1.1—2.67
fl.oz 30%
FIC/lOO lb
seed
(30% FIC)
or
0 • 8—1.25
fl.oz 40%
F1C/100 lb
seed
(40% FIC)
Issued: 6—05—84 111—009001—41
85
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF.BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Sudangras s (continued)
0.5 oz/l00 Seed treatment. May be applied by
lb seed planter box or dry method.
(25% D)
(75% WP/D)
/28020AA Sugar Beets No tolerance established.
Seed treatment through 4 ounces per
100 pounds of seed.
INAKABA Seedcorn beetle 3—4 oz/l0O Seed treatment. Apply by slurry
IOACAHA Seedcorn maggot lb seed method. Apply 1 pint of liquid
INBPAAA White grubs (25%, 752 wP) slurry per 100 pounds of seed.
INAVAAA Wireworms (75% WP/D)
(2.67, 4 lb/
gal RTU)
or
10.8 fl.oz
30% F1C/l00
lb seed
(30% F1C)
or
8 fl.oz 40%
F1C/l00 lb
seed
(40% FIC)
4 oz/lOO lb Seed treatment. May be applied by
seed planter box or dry method.
(25% D)
(25%, 75%
WP ID)
/28021AA Sunflower No tolerance established.
Seed treatment through 1 ounce per
100 pounds of seed for slurry and
dry methods or 2 ounces per bushel
of seed for planter box method.
INAKABA Seedcorn beetle i oz/lOO lb Seed treatment. Apply by slurry
IOACAHA Seedcorn maggot seed method. Apply 0.5 pint of liquid
INBPAAA White grubs (252, 75% WP) slurry per 100 pounds of seed.
INAVAAA Wireworms (75% WP/D)
(2.67, 4 Ib/
gal RTU)
or
Issued: 6—0584 IIF00900l42
86
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLOLUDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Sunflower (continued)
4 fl.o 25%
EC, RTLJ/lOO
lb seed
(25% EC)
(25% RTLJ)
or
2.67—4 fl.o
30% FIC/lO0
lb seed
(30% FIC)
or
2—3 fl.oz 40%
F1C/100 lb
seed
(40% FlC)
2 oz/bu Seed treatment. Apply by planter
(25% WP/D) box method.
-—OR MAI--
0.56 oz/bu
(18.75% D)
or
1 ozflOO lb
seed
(25% D)
or
4 fl.oz 8.62
RTU/l0O lb
seed
(8e6Z RTU)
1 oz/100 lb Seed treatment. Apply by dry meth—
seed od.
(75% WP/D)
Issued: 6—05—84 111—009001—43
87
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF.BENZENE HEXACHLORIDE)
/IIOO5AA
Site and Pest
Tomato
Dosages and
Formulation(s )
Tolerance, Use, Limitations
3 ppm
Do not apply after fruit starts to
form through 0.75 pound per acre.
Preplant soil application through
2.06 pounds per acre.
Seed treatment through 2 ounces per
100 pounds of seed.
IRACAAA
ITBCCZA
I NAMCFA
INAMACA
INAMADA
IMAAACA
IQAQAAA
IMOAAAA
Aphids
Climbing cutworms
Colorado potato
beetle
Cucumber beetle8
Flea beetles
Leafminers
Plant bugs
Th rips
0.1—0.4 lb/A
(1% D)
or
0.25 ib/iQO
gal
(6% wP)
or
0.25 tsp
actual*/gal
or
0.19—0.75
lb/A
(25% wP)
or
0.03 oz**/gal
(0.36 lb/gal
EC)
or
0.31—0.33
lb/100 gal
or
0.32—0.75
lb/A
(1.6, 1.63,
1.7 lb/gal
EC)
(10.68% EC)#
Issued: 6—05—84
0.25—0.5 lb/A
(6%, 25% WP)
or
0.41—0. 52
lb/A
(1.65 lb/gal
EC)
or
0.3 lb/laO
gal
(10.68% EC)#
or
Preplant soil application. Spray
directly on soil, then disc as soon
as practicable to give thorough dis-
tribution in upper 4 to 6 inches of
soil. For garden symphylan , apply
the higher dosage for heavy infesta—
Lion.
tII—00900144
Foliar application. For leafminers ,
apply the higher dosage.
ITBCABA
I NAMB IC
INBPAAA
INAVAAA
Cu two rm S
Diabrotica beetles
(larvae)
White grubs
Wireworius
88
-------
EPA Index to Pesticide Chemicals
LINDANE (CAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Tomato (continued)
0.03—0.04
oz / gal
[ 0.8 gal/l0O
sq.ft]
(12.52, 202
EC ) #
IJDAABA Garden syinphylan 1.24—2.06
lb/A
(1.65 lb/gal
EC)
INAKABA Seedcorn beetle 2 oz/l0O lb Seed treatment. May be applied by
IOACAHA Seedcorn maggot seed slurry, planter box or dry method.
INBPAAA White grubs (25% D)
INAVAAA Wireworms (25%, 75% WP)
(25%, 75%
WP/ D)
/28065AA Wheat No tolerance established.
Seed treatment through 0.5 ounce per
100 pounds of seed for slurry and
dry methods or 2 ounces per bushel
for planter box method.
INAKABA Seedcorn beetle 0.25—0.5 oz/ Seed treatment. Apply by slurry
I OACAHA Seedcorn maggot 100 lb seed method. Apply 0.5 pint of liquid
INBPAAA White grubs (25%, 75% wP) slurry per 100 pounds of seed.
INAVAAA Wireworms (75% WP/D)
(2.67, 4 lb/
gal RTU)
or
1—2 fl.oz 252
EC, 30% F1C,
25% RTU/l00
lb seed
(25% EC)
(30% FIC)
(25% RTU)
or
1—3 fl.oz 40%
FIC/l0O lb
seed
(402 FIC)
Issued: 6—05—84 111—009001—45
89
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF •BENZENE 1LEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Wheat (continued)
2 ozlbu Seed treatment. Apply by planter
(25% WP/D) box method.
or
0.5—2 oz/lOO
lb seed
(25% D)
(25% WP/D)
--OR MAt--
0.5—0.81 oil
100 lb seed
(12.5%, 25%
D)
or
0.28—0.3 75
oz / bu
(18.75% D)
or
3 fl.oz 8.6%,
10.5% RTU/bu
(8.6%, 10.5%
RTU)
°i ? 5 s. i Seed treatment. Apply by dry meth—
(75% wP)
(75% WP/D)
Issued: 60584 111—009001—46
90
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
TERRESTRIAL NON—FOOD CROP
( Agricultural Crops )
/260O3 Tobacco
Foliar application through 0.2 pound
per acre.
Transplant water treatment through
2 ounces per 100 gallons of water.
ITBCAEA Cutworms 2 oz/l0O gal Transplant water treatment. From
INAVAAA Wireworms transplant tobacco setter water tank, move
water transplanting water through hose to
(25% VP) setter shoe, and dispense into roots
or of plants mechanically as setter
4 fl.oz 10% finger releases plant and plant
EC/100 gal roots are covered with soil inside
transplant setter shoe. Apply 0.5 pint of
water finished spray per plant or 200 to
(10% EC) 250 gallons per acre.
or Do not dip tobacco roots directly
2—4 fl.oz 20% into solution as root damage may
EC/lOO gal occur.
transplant
water
(20% EC)
IRACCUA Green peach aphid 02 lb/A Foliar application to plant beds.
(1% D)
I 111—009001—47
Issued: 6—058,
91
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
( Ornamental Plants )
35022AA Ash
ITBQAEA Lilac borer 0.5 lb/100 RESTRICTED USE PESTICIDE.
gal Bark application. Apply in late
or June or early July.
0.5 tbls
ac tua 1*/gal
(25% WP)
or
3 pt 20% Ed
100 gal
or
I tbls 20%
EC/gal
(20% EC)
1.6 gal 5% Bark application. Apply in late
EC/lOO gal June or early July.
or
4 cbls 5%
EC/gal
(5% EC)
Refer to Aspen for additional information.
Refer to Boxelder cluster for additional informa-
tion.
/35023AA Aspen
/35022AA
/ 35049AA
13507 7AA
/35083AA
/35101AA
/35128AA
IRACAAA Aphids 1.2 lb/lOO RESTRICTED USE PESTICIDE.
INBQAAA Bark beetles gal Foliar and bark application. Apply
INAAADA Wood boring beetles or in spring when buds begin to break.
02 oz**/gal Repeat in 10 to 14 days.
(1.63 lb/gal
EC)
or
1.25 gal
12.5% EC/100
gal
(12.5% EC)
or
Issued: 6—05—84 111—009001—48
92
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EPA Index to Pesticide Chemicals
LINDANE (GA1 1MA ISOMER OF.BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Aspen (continued)
3 cbls 12.5%
ECIgal
(12.5% EC)
or
0.75 gal 20%
EC/100 gal
or
2 tbls 20%
EC/gal
(20% EC)
3 gal 5% EC/ Foliar and bark application. Apply
100 gal in spring when buds begin to break.
or Repeat in 10 to 14 days.
9 tbls 5% Ed
gal
(5% EC)
or
0.75 gal 20%
EC/l00 gal
or
2 tbls 20%
EC / gal
(20% EC)
/35024AA Austrian Pine
/35 1 13AA
/35126AA
IRAVALA Pine bark adelgid 0.25 lb/lOG RESTRICTED USE PESTICIDE.
gal. Bark application. Apply when inuna—
(25% WP) ture adelgids are present.
/34022AA Azalea
INALBU Azalea stem borer 3 pt 20% Ed RESTRICTED USE PESTICIDE.
100 gal Bark application. Make 2 to 3 ap—
or plications at 7 to 10 day intervals
I tbls 20% in May and June.
EC/gal
(20% EC)
Issued: 6—05—84 1 1 1—009001—49
93
-------
EPA Index to Pesticide Chemicals
IJINDANE (GAMMA ISOMER OF.BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Azalea (continued)
IQAXAAA Lace bugs 0.3—0.5 lb/A RESTRICTED USE PESTICIDE.
(1% D) Foliar application. Apply just af—
or ter hatching and when small nymphs
0.25—0.375 first appear. Repeat in 10 days or
lb/l00 gal as needed. This will usually be
or about May 15 and at 30 day inter—
0.25 tbls vals.
actual*/gal
(25% WP)
or
0.3 lb/100
gal
or
0.05 oz**/gal
(1.65 lb/gal
EC)
or
3 pt 10% EC/
100 gal
or
3 tsp 10%
EC/gal
(10% EC)
2.5 Pt 12.8% Foliar application. Apply in spring
EC/100 gal when nymphs first appear and repeat
or as needed.
1 tbls 12.8%
EC/gal
(12.8% EC)
Refer to Cainellia for additional information.
/35027AA Beech
/35028AA
/35049AA
/35083AA
/ 3511 9AA
/35 128AA
IRACAAA Aphids 0.25 lb/l00 RESTRICTED ElSE PESTICIDE.
gal Foliar application. Apply when new
(25% WP) growth is about 2 inches long, be-
fore leaves curl. Repeat as needed.
Refer to Boxelder cluster for additional
information.
Issued: 6—05—84 11 1—009001—50
94
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF.BENZENE HEXACHLORIDE).
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/35028AA Birch
IMAAAGA Leafminers (in— 0.25 lb/ba RESTRICTED USE PESTICIDE.
cluding birch gal Foliar application. Apply when
leafminer) (25% VP) small miners appear in early and
or mid—May. Repeat in 4 to 6 weeks to
0.03 oz**/gal control second generation.
(1.63 lb/gal
EC)
or
2 tsp 12.5%
EC/gal
(12.5% EC)
or
I pt 20% EC/
100 gal
or
I tsp 20% Ed
gal
(20% EC)
4.5 tsp 5% Foliar application. Apply when
EC/gal small miners appear in early and
(5% EC) mid—May.
or
1 tsp 20%
EC/gal
(20% EC)
Refer to Beech for additional information.
Refer to Cottonwood for additional information.
/35034AA Boxelder
/35071AA Horsechestaut
/35 075AA Linden
/3 502 2AA
/35027AA
/35 133AA
/35049AA
/35083AA
/35093AA
/35 101AA
/ 351 19AA
/35 128AA
INAHAAA Flatheaded wood —— Bark application. Pour product into
borers (1% RTU) a sprayer bottle that can be adjust-
ed to deliver a pinpoint stream.
Inject into feeding entry hole. Re-
Issued: 6—05—84 111—009001—51
95
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Boxelder cluster (continued)
peat in 5 to 7 days if feeding signs
are still observed. Do not apply
as a treatment that encircles a limb
or trunk since damage will result
to plant. Apply as soon as symptoms
are first observed. The symptoms
can include a damp spot on the bark
at the point of early infestation,
developing until the sap drips from
the spot; discoloration of bark
overlying the tunnel; and the pos-
sible appearance of dry feces at the
entrance to or just below the tun-
nels. If the treated areas have not
dried within 7 to 10 days, treatment
should be repeated.
/34O31AA Boxwood
IOAMASA Boxwood leafminer 0.25 lb/bc) RESTRICTED USE PESTICIDE.
IRAXAIA Boxwood psyllid gal Foliar application. For leafminera ,
(25% WP) apply when new growth appears. F
payllid , apply when new growth ap-
pears and repeat in 7 days.
/35152AA California Red Fir
/35159AA Coulter Pine
/35164A.A Digger Pine
/35044AA Douglas—Fir
/35196AA Monterey Pine
/35 100AA Ponderosa Pine
/35219AA Sugar Pine
/35228AA White Fir
INBQAVA Douglas—fir beetle 1.7 lb/15 gal RESTRICTED USE PESTICIDE.
INBQAUA Mountain pine fuel oil or Bark application. Apply 7 days be—
beetle water fore adults begin to emerge. Hold
INBQANA Western pine beetle (1.33 gal/ the spray nozzle between 1 and 1.5
235 sq.ft feet from bark during application.
total bark Applicationto the point of runoff
surface is unnecessary, instead make an ac—
area] curate, uniform application.
(1.7 lb/gal
EC)
Issued: 6—05—84 111—009001—52
96
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EPA Index to Pesticide Chemicals
LINDANE (GANNA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Do8age8 and Tolerance, Use, Limitations
Formulation(s )
/34036AA Camellia
/ 3402 2AA
/34 118AA
INAMACA Cucumber beetles 0.2 lb/l0O RESTRICTED USE PESTICIDE.
(adults and lar— gal Soil application. Saturate 8oil
vae) (1,7 lb/gal around plants in beds. For potted
INASCWA Fuller rose beetle EC) plants, spray soil surface lightly.
(adults and lar— or
vae) i. pt 20% Ed
INASCTC Otiorhynchus wee— 100 gal
vils (larvae) or
INASCQA Strawberry root I tsp 20% Ed
weevil gal
INAVAAA Wireworms (20% EC)
1 tsp/gal/50 Soil application. Apply to soil
sq.ft around plant in spring and fall.
(5% EC) Formulated with dicofol, carbaryl,
and malathion.
4 tsp/gal/ Soil application. Apply to soil
35 sq.ft around plants.
(5% EC) Formulated with dicofol, methoxy-
chlor, and malathion.
/35039AA Chestnut
INAHAEA Twolined chestnut 0.5 lb/lOO RESTRICTED USE PESTICIDE.
borer gal Bark application. Make 2 applica
or tions in mid and late June.
0.5 tbls
actual*/gal
(25% WP)
or
3 Pt 20% Ed
100 gal
or
I tbls 20%
EC/gal
(20% BC)
1.6 gal 5% Bark application. Make 2 applica—
EC/100 gal tions in mid and late June.
or
4 tbls 5%
EC/ gal
(5% EC)
Issued: 6—05—84 111—009001—53
97
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF.BENZENE FIEXACI4LORIDE)
Site and Pest
Dosages and
Formulation(s)
Tolerance, Use, Limitations
/ 30005AA
Christmas Tree Plantations
IRAVAFA
Balsam woolly
adelgid
0.8 lb/lOO
gal diesel
oil
(1.6 lb/gal
EC)
RESTRICTED USE PESTICIDE.
Bark and foliar application. Apply
to base of tree 18 inches up, higher
if there are infestations. Spray
entire tree during May, June, or
July. In case of danger to shrub-
bery or lawns, substitute water for
diesel oil.
INBQAAA
Bark beetles
0.7 oz/gal
(1.7 lb/gal
EC)
RESTRICTED USE PESTICIDE.
Bark application. Spray trunks and
branches of growing trees June 1 and
again about August 1.
Refer to Ornamental Evergreens for additional
information.
/31065AA
IQAXAAA
Chrysanthemum
Lace bugs
0.3—0.5 lb/A
(1% 1)
RESTRICTED USE PESTICIDE.
Foliar application. Apply when
pests first appear and repeat as
needed.
/ 351 33AA
/ 350 28AA
/ 3510 1AA
/351 28A.A
Cottonwood
INAHABA
Bronze birch borer
0.5 lb/100
gal
or
0.5 tbls
ac tua 1*/gal
(25% WP)
or
3 pt 20% EC/
100 gal
or
1 tbls 20%
EC/gal
(20% EC)
RESTRICTED USE PESTICIDE.
Bark application. Apply in mid and
late June.
Issued: 6—05—84
111—009001—54
98
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Càttonvood (continued)
1.6 gal 5% Bark application. Apply in mid and
EC/l0O gal late June.
or
4 tbls 5%
EC/gal
(5% EC)
Refer to Boxelder cluster for additional informa-
tion.
/31083DA Daffodil
INAVAAA Wireworms 0.5—0.75 ozJ RESTRICTED USE PESTICIDE.
100 bulbs Bulb application. Dust bulbs at
(25% WPID) time of planting.
Refer to Hyacinth cluster for additional informa-
tion.
/35043AA Dogwood
ITBQAOA Dogwood borer 0.5 ibis RESTRICTED USE PESTICIDE.
actual*/gai Bark application. Make 2 to 3 ap—
or plications at 7 to 10 day intervals
0.75 lb/100 in May and early June. Apply to
gal trunk and lower limbs, particularly
(25% WP) to injured areas and old borer
or wounds.
0.1 oz**/gal
(1.63, 1.65
lb/gal EC)
or
0.6 lb/l00
gal
(1.65 lb/gal
EC)
or
6 pt 10% EC/
100 gal
or
2 tbls 10%
EC/gal
(10% BC)
or
5 tsp 12.5%
EC/gal.
(12.5% BC)
or
Issued: 6—05—84 111—009001—55
99
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EPA Index to Pesticide Chemicals
LINDANE (CA 4MA ISOMER OF BENZENE HEXACHLORIDE).
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Dogwood (continued)
3 pt 20% Ed
100 gal
or
1 tbls 20%
EC/gal
(20% EC)
1.6 gal 5% Bark application. Make 2 to 3 ap—
EC/l00 gal plications at 7 to 10 day intervals
or in May and early June.
4—4.5 tbls
5% EC/gal
(5% EC)
or
S pt 12.8%
EC/100 gal
or
5 tsp 12.8%
EC/gal
(12.8% EC)
or
1 tbls 20%
EC/gal
(20% EC)
/35049AA Elm (including English Elm and
Scotch Elm)
INBQAAA Bark beetles -— Bark application. Pour product into
(1% RTU) a sprayer bottle than can be adjust-
ed to deliver a pin point stream.
Inject into entrance holes of the
borers. Repeat in 5 to 7 days if
feeding signs are still observed.
Do not apply as a treatment that en-
circles a limb or trunk since damage
will result to plant.
IMAAACA Leafminers (in— 0.25 lb/lOG RESTRICTED USE PESTICIDE.
cluding elm leaf— gal Foliar application. Apply when
miner) (25% WP) small miners appear in early and
or mid—May. Repeat 2 or 3 weeks later
0.03 oz**/gal to control second generation.
(1.63 lb/gal
EC)
or
Issued: 6—05—84 III—00900156
1.o0
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMNA ISOMER OF .BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
Elm (including English Elm and Scotch Elm) (continued)
2 tsp 12.5%
EC/gal
(12.5% EC)
or
I pt 20% Ed
100 gal
or
I tsp 20%
EC/gal
(20% EC)
4.5 tsp 5% Foliar application. Apply when
EC/gal small miners appear in early and
(5% EC) mid—May.
or
1 tsp 20%
EC/gal
(20% EC)
Refer to Aspen for additional information.
Refer to Beech for additional information.
Refer to Boxelder cluster for additional informa-
tion.
/3505 1AA Fir
IRAVAFA Balsam woolly 0.8 lb/lOO RESTRICTED USE PESTICIDE.
adelgid gal diesel Bark and foliar application. Apply
oil to base of tree 18 inches up, higher
(1.6 lb/gal if there are infestations. Spray
EC) entire tree during May, June, or
July. In case of danger to shrub-
bery or lawns, substitute water for
diesel oil.
/35055AA Flowering Cherry
IQAXAAA Lace bugs 0.25 lb/lOO RESTRICTED USE PESTICIDE.
gal Foliar application. Apply just af—
(252 wP) ter hatching and when small nymphs
can be seen. Repeat in 10 days.
Refer to Flowering Ornamental Fziiit Trees for
additional information.
Issued: 6—05—84 IIF00900l57
101
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF•BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/xxxxxAA Flowering Ornamental Fruit Trees
IRACAAA Aphids 0.25 lb/lOO RESTRICTED USE PESTICIDE.
gal Foliar application. Apply when new
(25% WP) growth is about 2 inches long, be-
fore leaves curl. Repeat as needed.
INALBNA Roundheaded apple— os lb/loo RESTRICTED USE PESTICIDE.
tree borer gal Bark application. Apply at 21 day
or intervals from June to August.
0.5 tbls
actual*/gal
(25% Wi’)
or
3 pt 20% Ed
100 gal
or
1 tbls 202
EC/gal
(20% EC)
1.6 gal 5% Bark application. Apply at 21 day
EC/lOO gal intervals from June to August.
or
4 tbls 5%
EC/gal
(52 EC)
/3llllAA Gladiolus
/ 31111 DA
IMOAAAA Thrips 0.1—0.4 lb/A Foliar application. Repeat as need—
(1% D) ed.
0.25—0.4 lb/A RESTRICTED USE PESTICIDE.
(12 D) Foliar application. Repeat as need-
or ed.
0.25 lb/100
gal
(25% WP)
—— Foliar application. Apply twice a
(1% D) week from early stages until spikes
begin to open. Repeat as needed at
7 to 10 day intervals until control
is achieved.
Formulated with ztneb and thiram.
Issued: 6—05—84 111—009001—58
102
-------
EPA Index to Pesticide Chemicals
LINDANE (GAI4MA ISOMER OF .BENZENE REXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Gladiolus (continued)
INAVAAA Wireworins 0.5—0.75 Oz/ RESTRICTED USE PESTICIDE.
100 bulbs Bulb application. Dust bulbs at
(25% WP/D) time of planting.
Refer to Tulips for additional information.
/34066AA Hawthorn
/35 093AA
/35 119AA
LQAXAAA Lace bugs 0.25 lb/100 RESTRICTED USE PESTICIDE.
gal Foliar application. Apply just af—
(25% WP) ter hatching and when small nymphs
can be seen. Repeat in 10 days.
/35068AA Hemlock
/35321AA Taxus Compacta
INASCSA Black vine weevil 0.1 oz**/gal RESTRICTED USE PESTICIDE.
INASCQA Strawberry root (1.63 lb/gal Bark application. Apply in May or
weevil EC) early June to the trunks and around
or base of trees soaking the bark and
5 tsp 12.5% wetting the soil surface.
EC/gal
(12.5% EC)
or
3—4 Pt 20%
EC/100 gal
of
1 tbls 20%
Ed gal
(20% EC)
4.5 tbls 5% Bark application. Apply in May or
EC/gal early June to the trunks and around
(5% EC) base of trees soaking the bark and
or vetting the soil surface.
1 tbls 202
EC/gal
(20% EC)
lesued: 6—05—84 111—009001—59
103
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF.BENZENE HEXACHLORLDE).
Site and Pest Dosages and Tolerance 1 Use, Limitations
Formulation(s )
/34070AA Holly
IMAAACA Leafminers 1 pt 20% Ed RESTRICTED USE PESTICIDE.
100 gal Foliar application. Apply when
or adult miners appear in April and
1 tsp 20% mid—May. Repeat when smaLler miners
EC/gal appears in July.
(20% Ec)
/3ll23DA Hyacinth
/31 142DA Narcissus
/3].083DA
IRACAAA Aphids 0.1 lb/40 gal RESTRICTED USE PESTICIDE.
I OBJAFA Bulb flies (6% WP) Bulb application. Apply as a spray
ITBMCCA European corn borer (1.63 lb/gal when pests first appear and repeat
ITBCBUA Iris borer EC) as needed.
IMOAAAA Thrips or
1 Pt 10.68%
EC/40 gal
or
2.4 tsp
10.68% Ed
gal
(10.68% EC)
/3 1 126AA Iris
/31126DA
IRACAAA Aphids 0.1 lb/40 gal RESTRICTED USE PESTICIDE.
IOBJAFA Bulb flies (6% WP) Bulb application. Apply as a spray
ITBMCCA European corn borer (1.63 lb/gal when pests first appear and repeat
ITBCBUA Iris borer Ed) as needed.
IMOAAAA Thrips or
1 pt 10.68%
EC/40 gal
or
2.4 tsp
10.68% Ed
gal
(10.68% EC)
or
5 tsp 12.5%
EC/ gal
(12.5% EC)
or
I. tbls 20%
EC/ gal
(20% EC)
Issued: 6—05—84 111—009001—60
104
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF .BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Iris (continued)
ITBCBUA Iris borer I tsp 20% RESTRICTED USE PESTICIDE.
EC/gal Foliar application. In early spring
(20% EC) destroy old leaves. Apply during
April and May.
4 tsp 5% Foliar application.
EC/gal
(5% EC)
/35 185AA Japanese Black Pine
/35113AA
/35126AA
INASDBA White pine weevil 2 qt 20% Ed RESTRICTED USE PESTICIDE.
100 gal Foliar application. Apply thorough—
or ly covering terminals. Apply during
1.33 tbls 20% April in Northeastern United States.
EC/gal Consult your State Agricultural Ex—
(20% EC) tension Service for timing in other
areas.
/35073AA Juniper
INALECA Twig girdler 1 tbls 20% RESTRICTED USE PESTICIDE.
EC/gal Foliar application. Make 2 appli—
(20% EC) cations at 30 day intervals. In
northern CA, apply June and mid—
July. In southern CA, apply April
and May.
1 tbls 20% Foliar application. Make 2 appli—
EC/gal cations at 30 day intervals. In
(20% EC) northern CA, apply June and mid—
July. In southern CA, apply April
and May.
/34089AA Lilac
!TBQAEA Lilac borer 0.5 lb/100 RESTRICTED USE PESTICIDE.
gal Bark application. Make 2 to 3 ap
or plicationa at 7 to 10 day tntervala
0.5 tbls in May and early June. Apply to
actual*/gal trunk and lower limbs, particularly
(25% wP) to injured areas and old borer
or wounds.
0.1 oz**/gal
(1.63, 1.65
lb/gal EC)
or
Issued: 6—05—84 ItI—00900l6l
105
-------
EPA Index to Pesticide Chemical.
LINDANE (cAn tA ISOMER OF BENZENE HEXACRLORIDE)
Site and Pest
Lilac (continued)
Dosages and
Formulation(s )
Tolerance Use 1 Limitation .
0.6 lb/tOO
gal
(1.65 lb/gal
EC)
or
5 tsp 12.5%
EC/gal
(12.52 EC)
or
3 pt 20% Ed
100 gal
or
1 tbls 20%
EC/gal
(20% EC)
1.6 gal 5%
EC/l00 gal
or
4—4.5 tbls
EC/gal
(5% EC)
or
5 pt 12.8%
EC/l00 gal
or
5 tsp 12.8%
EC/ga 1
(12.8% EC)
or
1 tbls 20%
Ed/gal.
(20% EC)
Bark application. Make 2 to 3 ap—
plicat ions at 7 to 10 day intervals
in May and early June.
Aphids
Bulb flies
European corn borer
Iris borer
Thripa
Issued: 6—05—84
0.1 lb/40 gal
(62 WP)
(1.63 lb/gal
EC)
or
I pt 10.68%
ECI4O gal
(10.68% EC)
or
111—009001—62
106
5%
Lilies
/ 3113 iDA
IRACAAA
IOBJAFA
ITSMCCA
ITBCBUA
IMOAAAA
RESTRICTED USE PESTICIDE.
Bulb application. Apply as a spray
when pests first appear and repeat
as needed.
-------
EPA Index to Pesticide Chemicals
LINDANE (GANMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest and Tolerance 1 Use Limitations
Forinulat ion(s)
Lilies (continued)
2.4 tsp
10.68% Ed
gal
(10.68% EC)
or
5 tsp 12.5%
EC/gal
(12.5% EC)
or
I tbls 20%
Ed gal.
(20% EC)
/35O77AA Locust (including Black Locust)
INAHAWA Honeylocust borer 1.6 gal 5% Bark application. Apply in early
EC/lO0 gal June.
or
4 tbls 57.
EC/gal
(5% Ed)
IMAAAGA Leafminers (in— 0.25 lb/100 RESTRICTED USE PESTICIDE.
cluding locust gal Foliarapplication. Repeat when
leafminer) (25% wP) small miners appear in early July.
or Make 1 or 2 additional applications
0.03 oz**/gal as new miners and adult feeding ap—
(1.63 lb/gal pear.
EC)
or
2 tsp 12.5%
EC/gal
(12.5% EC)
or
I pt 20% EC/
100 gal
or
I tsp 20%
EC/gal
(20% EC)
4.5 tsp 5 Foliar application. Apply when
EC/gal small miners appear in early July.
(5% EC)
or
I tsp 20%
Ed gal
(20% Ec)
Issued: 6—05—84 t 1 1009001—63
107
-------
EPA Index to Pesticide Chemicals
LIINDANE (GAMMA ISOMER OF. BENZENE LIEXACHLORIDE).
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Locust (including Black Locust) (continued)
INALAPA
Locust borer
0.5 lb/l00
gal
or
0.5 tbls
actual*/gal
(25% WP)
or
3 pt 20% Ed
100 gal
or
1 tbls 20%
EC/gal
(20% EC)
RESTRICTED USE PESTICIDE.
Bark application. Apply in early
June.
Refer to Aspen for additional information.
Refer to Aspen
Refer to Beech.
Refer to Boxelder cluster.
INALBNA
Roundheaded apple—
tree borer
1.6 gal 52
EC/l00 gal
or
4 tbls 5%
EC/gal
(5% EC)
Bark application. Apply at 21 day
intervals from June to August.
/ 31 142DA
Narc issus
IRACAAA
IOBJAFA
ITBMCCA
ITBCBUA
IMOAAAA
Aphids
Bulb flies
European corn borer
Iris borer
Th rips
Issued: 6—05—84
0.1 lb/40 gal
(6% wP)
(1.63 lb/gal
EC)
or
I pt 10.68%
EC/40 gal
or
2.4 tsp
10.68% Ed
gal
(10.68% EC)
111—009001—64
/35083AA
/35085AA
Maple
Mountainash
RESTRICTED USE PESTICIDE.
Bulb application. Apply as a spray
when pests first appear and repeat
as needed.
108
-------
EPA. Index to Pesticide Chemicals
LINDANE (GAZ1MA ISOMER OF .BENZENE HEXACHLORIDE)
Site and Peat Dosages and Tolerance 1 Use, Limitations
Formulation(s )
/35093AA
Refer to Hawthorn.
Refer to Boxelder cluster.
/35000AA Ornamental and/or Shade Trees
INBQAAA Bark beetles 2.5 gal 20% RESTRICTED USE PESTICIDE.
EC/100 gal Bark application. Apply as soon as
or possible after damage has been done
6 tbls 20% to tree.
EC/gal
(20% EC)
INBQBIA Pine engraver I lb/55 gal RESTRICTED USE PESTICIDE.
INBQAOA Southern pine (1 lb/gal EC) Bark application. Apply to entire
beetle length of tree at first sign of in-
festation. Repeat at 30 day inter-
vals. If heavy infestations are in
the vicinity, preventative sprays
may be used for valuable trees.
INBQAOA Southern pine 4.5 qt 20% RESTRICTED USE PESTICIDE.
beetle EC/l00 gal Bark application. Apply Co the
fuel. oil point of runoff to aid in control
or of pest.
3 tbls 20%
EC/gal fuel
oil
(20% EC)
1.2—2.5 gal RESTRICTED USE PESTICIDE.
20% EC/lO0 Bark application. Apply before
gal trees are attacked when epidemic in
or the vicinity.
3—6 tbls 20%
EC / gal
(20% EC)
INBQAYA Turpentine beetles I lb/l4 gal RESTRICTED USE PESTICIDE.
diesel oil Bark application. Apply to the baa—
(1 lb/gal EC) al 18 inches of the trunk, higher
if infestation is present. Repeat
at 30 day intervals. Shade trees
examined regularly need not be
sprayed until infestation begins.
In case of danger of injury to
shrubbery, substitute water for oil.
Issued: 6—05—84 tII —00900l65
109
-------
EPA Index to Pesticide Chemicals
LINDANE (GANNA ISOMER OF .BENZENE HEXACHLORIDE)
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Ornamental and/or Shade Trees (continued)
13 tbls 20%
EC/gal
(20% SC)
RESTRICTED USE PESTICIDE.
Bark application. Spray trunk to
about 12 feet from ground to the
point of runoff.
Refer to Ornamental Evergreens for additional
information.
Refer to Ornamental Woody Shrubs for additional
information.
/ 3 5006AA
Ornamental Deciduous Trees
1 oz/gal
(1 lb/gal SC)
or
6 fl.oz 17%
EC/ga].
(17% EC)
RESTRICTED USE PESTICIDE.
Bark application. Apply as a pre-
ventative spray on uninfested trees.
Spray the main trunk of the tree
thoroughly up to 8 feet above the
ground. Make first application in
early spring and repeat at 3 to 6
month intervals. For control of
borers, clean out borer hole using
knife or wire probe. Inject undi-
luted into holes with stream type
applicator and seal with mud or
putty.
/3200 5AA
/30005AA
/ 35 000AA
Ornamental Evergreens
Aphids (including
balsam twig aphid
and white pine
aphid)
Birch leafminer
Elm leafminer
European hornet
Lace bugs
Psyllids
Spittlebugs (in-
cluding pine
spittlebug)
Thr ips
Issued: 6—05—84
RESTRICTED USE PESTICIDE.
Foliar and/or bark application. A
minimum of 3 applications is neces-
sary for effective control; May 10
to 15, June 1, and July 1. In cold-
er latitudes such as upstate New
York, apply approximately May 15 to
20, June 10, and July 10.
111—009001—66
INAHAAA
INALAAA
Flatheaded wood
borers
Roundheaded wood
borers
IRACAAA
I S BEANA
I SBEANA
ISBIA IA
IQAXAAA
I RA.XAAA
IRAEAAA
IMOAAAA
0.3 lb/l0O
gal
or
0.05 oz**/gal
(1.7 lb/gal
EC)
110
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Ornamental Evergreens (continued)
IMAAACA Wood boring insects 0.85 lb/lOO
(including bronze gal
birch borer, car— or
penterworm, dog— 0.14 oz**/gal
wood borer, elm (1.7 lb/gal
borer, leopard EC)
moth, lilac borer,
locust borer, pine
root collar wee-
vil, rhododendron
stem borer, sugar
maple borer, and
white pine weevil)
/330100A Ornamental Lawns
Keep children and pets off treated
areas until material has been washed
into the soil and the grass is com-
pletely dried.
ISASAAA Ants 1—2 tbls 5% Application to established lawns.
ITBCABA Cutworms EC/gal Formulated with dicofol, methoxy—
[ NBPAA.A White grubs [ 143 gall chlor, and malathion.
INAVAAA Wireworms 5,000 sq.ftl
(5% EC)
ISASAAA Ants 0.125 lb/ RESTRICTED USE PESTICIDE.
IRAFAAA Leafhoppers 5,000 sq.ft Application to established lawns.
IRAEAAA Spittlebugs (1% D) Repeat as needed.
(25% wP)
(1.65 lb/gal
SC)
or
1 pt 10% Ed
5,000 sq.ft
(10% EC)
0.2 lb/5,000 Application to established lawns.
sq.ft Apply after rain or watering and do
(1% D) not water for at least 2 days after
application. Repeat in 14 to 21
days if needed.
Formulated with dicofol, zineb,
dinocap, and carbaryl.
Issued: 6—05—84 111—009001—67
111
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF. BENZENE HEXACHLORIDE)’
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Ornamental Lawns (continued)
Armywo rm
Billbugs (larvae)
Cutworms
Fiery skipper (lar-
vae)
Lea fhoppers
Otiorhynchus wee-
vils (larvae)
Sod webworms
Symphy lens
Thr ips
White grubs
W ireworms
Issued: 6—05—84
Application to established lawns.
Mow lawn and water thoroughly I to
2 days prior to treatment. On di—
chondra and matted grass lawns,
sprinkle lightly immediately after
treatment to improve effectiveness.
Heavy watering or irrigation should
be withheld for 2 to 3 days follow-
ing treatment. Repeat at 4 to 6
week intervals if needed. However,
with extremely severe infestations
of cutworms (particularly on dichon—
dra lawns) a repeat application may
be required in 1 to 2 days. Appli-
cations are most effective during
the 2 hour period prior to darkness
when insects become active.
Formulated with naled.
111—009001—68
ITBCC FA
INASDUC
IT BCA BA
ITASADA
IRAFAAA
INASCTC
ITBMABA
U DAAAA
IMOAAAA
INBPAAA
1NAVAAA
40—53. 33
fl.oz 4.6%
EC/75 gall
5,000 sq.ft
(4.6% EC)
112
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF. BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/32000AA Ornamental Plants
/ 32000 DA
This broad site includes such specific sites as:
Arborvitae Forsythia Nasturtium
Aster Gardenia Pansy
Azalea Geranium Peony
Boxwood Gladiolus Petunia
Camellia Heather Primrose
Carnation Hemlock Rhododendron
Chrysanthemum Hibiscus Rose
Coleus Holly Snapdragon
Dahlia Hydrangea Spirea
Daisy Iris Sweet Pea
Delphinium Juniper Yew
Dogwood Larkspur Zinnia
EuonymouS Lilac
ISASAAA Ants 0.3—0.5 lb/A RESTRICTED USE PE STICIDE.
IRACAAA Aphids (including (1% D) Foliar application.
rose aphid) or
[ TBCCFA Armyworm 0.25 lb/l00
INASCSA Black vine weevil gal
INBGAAA Blister beetles (6%, 25% wP)
ITBCCSA Cabbage looper or
INAMACA Cucumber beetles 0.5—0.75 tsp
INAMBIA Diabrotica beetles actual*/gal
INANADA Flea beetles (in— (25% WP)
cluding larvae) or
INASCWA Fuller rose beetle 0.25 tbls
IVABAAA Grasshoppers actual*/gal
INBPAZA Japanese beetle (25% wP/D)
IQAXAAA Lace bugs or
IRAFAAA Leafhoppers (in— 0.2—0.25 lb/
cluding rose leaf— 100 gal
hopper) (1.6, 1.63,
IMAAAGA Leafminers (includ— 1.65 lb/gal
ing birch leaf— EC)
miner, boxwood or
leafininer, and oak 0.03—0.1
leafminer) oz**/gal
IMAAAEA Leafrollers (1.6, 1.65
IQAMAAA Plant bugs (includ— lb/gal EC)
ing fourlined or
plant bug and tar— 2—3 Pt 10%
nished plant bug) Ec/loo gal
IRAXAPA Psyllas (10% Ec)
INBPAUA Rose chafer or
INANCLA Rose leaf beetle
Issued: 6—05—84 111—009001—69
113
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Ornamental Plants (continued)
Pest list continued from previous page.
IRAEAAA Spittlebugs 2—3 tsp oz
IMOAAAA Thrips EC/gal
IRABAAA Whiteflies (10% EC)
or
2.5 pt 10.682
EC/l0O gal
or
2.4 tsp
10.68% Ed
gal
(10.68% EC)
or
2 pt 12.5%
EC/lOO gal
(12.5% EC)
or
2 tsp 12.5%
EC/gal
or
1—1.25 pt 20%
EC/lOO gal
or
1—1.2 tsp 20%
EC/gal
(20% EC)
or
6 fl.oz 30%,
40% FLC/100
gal
(30%, 40%
F ic)
0.03 oz**/gal Foliar application. Repeat at 7 to
(0.36 lb/gal 10 day intervals or as needed.
EC) May be formulated with one or a coin—
or bination of: dicofo], mancozeb,
2.5 pt 102 or zineb, methoxychlor, dinocap, naph—
12.8% EC/lO0 thalene, carbaryl, malathion,
gal sulfur 1 captan, and folpet.
or
1 tbls 102 or
12.8% EC/gal
(10%, 12.8%
EC)
or
Issued: 6—05—84 111—009001—70
114
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EPA Index to Pesticide Chemicals
LINDANE (GAJINA ISOMER OF .BENZENE HEXACHLORLDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Ornamental Plants (continued)
0.25 Pt 40%
EC/100 gal
(40% EC)
--OR MAI--
0.02 oz/lOO
sq. ft
(1% D)
or
0.24 lb/lOG
gal/A
or
0.15 tbls
actual*/gal
(3% WP)
or
0.09 oz/gal
(9% WP)
or
[ dust)
or
0.03 tbls
actual*/ga l
(0.5% WP/D)
or
[ dust]
or
0.08 tbls
actual*/gal
(1% WP/D)
or
2—12 tap 5%
EC/gal
(5% EC)
or
2—4 tbls 0.5%
F 1C/gal
(0.5% F1C)
Issued: 6—05—84 III—0090011l
115
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE REXACHLORIDE)
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
/34004AA
/35000AA
Ornamental Plants (continued)
Ornamental Woody Shrubs
Bark application. For borers in
trees and shrubs, apply when larvae
are active as is evidenced by fresh
borings being pushed to the surface
of the bark. Insert the applicator
into the burrow of the larvae and
squeeze a substantial quantity of
the formulation into the burrow.
Close the openings of the burrow
with wet soil after treatment unless
closed by the paste itself. After
treatment, re—examine regularly to
detect any bore damage neglected in
previous treatments. Repeat if
needed. For borers in flowers, in-
ject small amounts of formulation
into borer holes showing signs of
activity by the larvae. This is
indicated by borings or frass being
pushed through holes in the stems.
Inject in the lower hole if several
are present or where the freshest
signs of activily are indicated.
To avoid injury to tender plants a
very small portion, the size of a
small pea, should be injected.
INALAAA
Roundheaded wood
borers
Issued: 6—05—84
(1% RTU)
Bark application. Pour product into
a sprayer bottle that can be adjust-
ed to deliver a pinpoint stream.
Inject into feeding entry hole. Re-
peat in 5 to 7 days if feeding signs
are still observed. Do not apply
as a treatment that encircles a limb
or trunk since damage will result
to plant. The most successful
treatment is at the beginning of the
larval stage or during the pupal
stage at both of which times the
pests are located just under the
bark. Consult your State Agricul-
tural Extension Service to determine
the life cycle of the borer to be
controlled.
111—009001—72
IMAAACA
Wood boring insects ——
(including leopard (2% RTu)
moth, red oak
borer, and sugar
maple borer)
116
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACULORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/35098AA Pine
Around homes where there is danger
of phytotoxicity to plants or lawns
from oil drift, water dilution is
more desirable.
INBQAAA Bark beetles 0.7 oz/gal RESTRICTED USE PESTICIDE.
(1.7 lb/gal Bark application. Spray trunks and
EC) branches of growing trees June 1 and
again about August 1.
—— Bark application. Pour product into
(1Z RTU) a sprayer bottle that can be adjust-
ed to deliver a pin point stream.
Inject into entrance holes of the
borers. Repeat in 5 to 7 days if
feeding signs are still observed.
Do not apply as a treatment that en-
circles a limb or trunk since damage
will result to plant.
INBQAZA Black turpentine 1.375 oz/gal RESTRICTED USE PESTICIDE.
beetle water Bark application. Apply given dos
(1. lb/gal EC) age for prevention or control. Com—
or pletely cover the main tree trunk
8 fl.oz 17% from the first branches down to the
BC/gal water ground line, starting at the upper—
(17% EC) most point and working to the base
of the tree. Repeat at 3 to 6 month
intervals. Spray all trees in in—
fe8ted area to prevent attack by
beetles on uninfested trees. Do not
spray when bark is wet.
1.2 oz/gal RESTRICTED USE PESTICIDE.
water Bark application. Remove loose bark
(1 lb/gal EC) and trash exposing base of trunk.
Apply as a coarse spray to the point
of runoff. Spray from soil line to
2 feet above the ground. Repeat af-
ter 30 days.
9 fl.oz 112 RESTRICTED USE PESTICIDE.
EC/gal water Bark application. Spray lower 10
(11% EC) feet of tree, exposed roots, and
fresh stumps with a medium spray to
point of runoff. Apply at high
enough pressure to penetrate cracks
in bark of trees. Repeat as needed.
Do not spray when bark is wet.
Issued: 6—05—84 111—009001—73
117
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OFBENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Pine (continued)
INBQAZA Black turpentine 0.5 oz/gal RESTRICTED USE PESTICIDE.
beetle no. 2 fuel Bark application for prevention of
INBQBAA Red turpentine oil infestation. Spray only the bottom
beetle or 30 inches of trunk. Spray harvested
0.75 oz/gal logs or pulpwood from infested trees
water which are not removed immediately
(1 lb/gal EC) to prevent infestation of nearby
trees. Stumps of harvested trees
should be sprayed soon after cut-
ting.
I oz/gal no. RESTRICTED USE PESTICIDE.
2 fuel oil Bark application for control of
or existing infestations. Spray the
1.5 oz/gal bark surface of the trunk up to a
water height of 6 feet. Slough off the
(1 lb/gal EC) loose flaky bark and debris before
application. Use a cone—shaped
spray nozzle producing a coarse
spray and apply at high enough
pressure to force the spray into
cracks and crevices of bark. Apply
to the point of runoff, approxi-
mately 1 gallon per 40 to 50 square
feet of bark surface. Do not apply
more often that at 6 month inter-
vals.
INBQBYA Ips beetles 0.3 oz/gal RESTRICTED USE PESTICIDE.
water Bark application. Spray entire
(1 lb/gal EC) length of trunk and limbs at first
sign of infestation. Repeat at 30
day intervals as needed. Use pre-
ventative sprays during outbreak
periods.
4 fl.oz 17% RESTRICTED USE PESTICIDE.
EC/gal water Bark application. Apply given do s—
(17% EC) age for prevention or control. Com-
pletely cover the main tree trunk
from the first branches down to the
ground line, starting at the upper-
most point and working to the base
of the tree. Repeat at 3 to 6 month
intervals. Spray a11 trees in in-
fested area to prevent attack by
beetles on uninfested trees. Do not
spray when bark is wet.
Issued: 6—05—84 111—009001—74
118
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF .BENZENE LIEXACHLORIDE)
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Pine (continued)
2.5 gal 20%
EC/lOO gal
water or
fuel oil.
(20% EC)
RESTRICTED USE PESTICIDE.
Foliar application. Apply to young
seedlings in early April to May and/
or October.
RESTRICTED USE PESTICIDE.
Application to freshly cut stumps.
Apply in March or early April and/or
October. Apply thoroughly to tops
and sides of stumps to the point of
runoff.
IN BQBZA
Pine beetles (in-
cluding turpentine
beetles)
0.2 lb/5 gal
water
(1.63, 1.65
lb/gal EC)
or
0.3 ib/5 gal
water
or
0.2 lb/5 gal
kerosene or
no. 2 fuel
oil
(1.7 lb/gal
EC)
or
2 Pt 10% EC/5
gal water
[ 1 gal/50
sq.ft of
bark sur-
face]
(10% EC)
or
26 fl.oz
12.5% EC/5
gal water
(12.5% EC)
or
15 fl.oz 20%
EC/5 gal
water
(20% EC)
or
RESTRICTED USE PESTICIDE.
Bark application. Apply thoroughly
to the point of runoff to a height
of 6 feet. Apply at first sign of
infestation and repeat in 3 to 6
months if needed.
Issued: 6—05—84
111—009001—75
INASCYA
Northern pine wee— 2
vii
qt
100
20% Ed
gal
INASBRA
Pales weevil
(20%
EC)
119
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EPA Index to Pesticide Chemicals
LINDANE (GANNA ISOMER OF .BENZENE HEXAC}ILORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Pine (continued)
16 fl.oz 20%
EC/5 gal
water, kero—
sene, or no.
2 fuel oil
(20% EC)
2 qt 5% EC/5 Bark application. Apply thoroughly
gal water to the point of runoff to a height
(5% EC) of 6 feet. Apply at first sign of
or infestation and repeat in 3 to 6
1.5 Pt 12.8% months if needed.
BC/5 gal
water
(12.8% EC)
or
0.9—1 pt 20%
EC/5 gal
water
(20% EC)
INASBSA Pine root collar 3—4 pt 20% RESTRICTED USE PESTICIDE.
weevil EC/lOO gal Bark application. Apply in June to
or the trunks and lower branches and
1 tbls 20% soak the soil around the base of
EC/gal tree.
(20% EC)
INBQAOA Southern pine 0.3 oz/gal RESTRICTED USE PESTICIDE.
beetle water Bark application. Spray entire
(1 lb/gal EC) length of trunk and limbs at first
sign of infestation. Repeat at 30
day intervals as needed. Use pre-
ventative sprays during outbreak
periods.
0.75 oz/gal RESTRICTED USE PESTICIDE.
water Bark application. Apply given dos—
(1 lb/gal EC) age for prevention or control. Corn—
or pletely cover the main tree trunk
4 fl.oz 17% from the first branches down to the
EC/gal water ground line, starting at the upper—
(17% EC) most point and working to the base
of the tree. Repeat at 3 to 6 month
intervals. Spray all trees in in-
fested area to prevent attack by
beetles on uninfested trees. Do not
spray when bark is wet.
Issued: 6—05—84 111—009001—76
120
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF .BENZENE HEXACRLORIDE)
Site and Pest Dosages and Tolerance, Use Limitations
Formulation(s)
Pine (continued)
2.5 fl.oz 11% RESTRICTED USE PESTICIDE.
EC/gal. water Bark application. Spray entire
(11% EC) trunk with a medium spray to the
point of runoff. Apply at high
enough pressure to penetrate cracks
in bark of tree. Repeat in 30 to
60 days.
2.3 gal 20% RESTRICTED USE PESTICIDE.
EC/l0O gal Application to tops and stumps.
fuel oil Spray bark to the point of runoff
or to reduce populations left in tops
3 tbls 20% and stumps.
EC/gal fuel
oil
(202 EC)
[ NASDBA White pine weevil 0.1 oz**/gal RESTRICTED USE PESTICIDE.
(1.63 lb/gal Delayed dormant application. Apply
EC) thoroughly to entire tree in late
or April when buds swell.
5 tsp 12.5%
EC/gal
(12.5% EC)
4.5 tbls 5% Delayed dormant application. Apply
EC/gal thoroughly to entire tree in late
(5% EC) April when buds swell.
or
3 pt 20% EC/
100 gal
or
1 tbls 20%
EC/gal
(20% EC)
ITBMBCA Zimmerman pine moth 0.5 lb/lOO RESTRICTED USE PESTICIDE.
gal Bark application. Apply late
or August.
0.5 tbls
actua l*/ga l
(25% WP)
Issued: 6—05—84 111—009001—77
121
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EPA Index to Pesticide Chemicals
LINDANE (GANNA ISOMER OF.BENZEHE HEXACHLORIDE)
Site and Pest Dosagea and Tolerances Use, Limitations
Formulation(s )
/351O1AA Poplar
Refer to Aspen.
Refer to Boxelder cluster.
Refer to Cottonwood.
/31284AA Primrose
INAMACA Cucumber beetles 1 tsp/gal/SO Soil application. Apply to soil
(adults and lar— sq.ft around plant in spring and fall.
vae) (5% EC) Formulated with dicofol, carbaryl,
INASCWA Fuller rose beetle and malathion.
(adults and lar-
vae) 4 tsp/gal/35 Soil application. Apply to soil
ENASCTC Otiorhynchus wee— sq.ft around plants.
vila (larvae) (5% EC) Formulated with dicofol, methoxy
INASCQA Strawberry root chior, and malathion.
weevil
INAVAAA Wireworms
/34058AA Pyracantha
T QAXAAA Lace bugs 0.3—0.5 lb/A RESTRICTED USE PESTICIDE.
(12 D) Poliar application. Apply when
or pests first appear and repeat as
0.375 lb/ba needed.
gal
(25% wP)
or
0.25 tbls
ac tual*/ gal
(25% WP)
or
0.3 lb/bOO
gal
or
0.05 oz**/gal
(1.65 lb/gal
EC)
or
3 Pt 10% EC/
100 gal
or
3 tsp 10%
EC/gal
(10% EC)
Issued: 6—05—84 III—00900178
122
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EPA Index to Pesticide Chemicals
L.INDANE (c ii ISOM OF.BENZENE HEXACHLORIDE).
Site and Pest and Tolerance, Use, Limitations
Forinulatjon(à)
Pyracantha (continued)
2.5 pt 12.8%
EC/iQO gal
or
1 tbls 12.8%
EC/gal
(12.82 EC)
/341 18AA Rhododendron Hybrida/Cultivars
IQAXAAA Lace bugs 0.3-0.5 lb/A RESTRICTED USE PESTICIDE.
(12 D) Foliar application. Apply just af—
or ter hatching and when small nymphs
0.25—0.375 first appear. Repeat in 10 days or
lb/l00 as needed. This will usually be
gal about May 15 and at 30 day inter—
(25% WP) vals.
or
0.25 tbls
actua l*/ga l
(25% wP)
or
0.3 lb/l00
gal
or
0.05 oz**/gal
(1.65 lb/gal
EC)
or
3 pt 10% Ed
100 gal
or
3 tsp 10%
EC/gal
(102 EC)
2.5 pt 12.8% Foliar application. Apply in spring
EC/l00 gal when nymphs first appear and repeat
or as nee4ed.
1 tbls 12.82
EC/gal
(12.82 EC)
Issued: 6—05—84 111—009001—79
123
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EPA Index to Pesticide Chemicals
LINDANE (GAM11A ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Rhododendron Hybrids/Cultivars (continued)
ITBQANA Rhododendron borer 0.1 oz**/gal RESTRICTED USE PESTICIDE.
(1.63, 1.65 Bark application. Make 2 to 3 ap—
lb/gal EC) plications at 7 to 10 day intervals
or in May and early June. Apply to
0.6 lb/l00 trunk and lower limbs, particularly
gal to injured areas and old borer
(1.65 lb/gal wounds.
EC)
or
5 tsp 12.5%
EC/gal
(12.5% EC)
or
3 pt 20% Ed
100 gal
or
I tbls 20%
SC/gal
(20% EC)
4—4.5 tbls Bark application. Make 2 to 3 ap—
5% EC/gal plications at 7 to 10 day intervals
(5% EC) in May and early June.
or
5 pt 12.8%
EC/l00 gal
or
5 tsp 12.8%
EC/gal
(12.8% EC)
or
1 this 20%
EC/gal
(20% EC)
Refer to Camellia for additional information.
Issued: 6—05—84 11 1—009001—80
124
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EPA Index to Pesticide Chemicals
LINDANE (GA A ISOMER OF .BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/34120AA Rose
ISASAAA Ants 0.02 oz/lO0 Foliar application. Repeat as need—
IRACAAA Aphids sq.ft ed .
INAMACA Cucumber beetles (1% D) Formulated with one or a combination
INAMB IA Diabrotica beetles or of: basic copper sulfate, dicofol,
INAZ4ADA Flea beetles mancozeb, zineb, methoxychior, dino—
INASCWA Fuller rose beetle (1% D) cap, carbaryl, and sulfur.
IVABAAA Grasshoppers (1% WP/D)
INBPAZA Japanese beetle or
IRAFAAA Leafhoppers (in— 0.24 lb/lOO
cluding rose leaf- gal/A
hopper) or
IQAMAAA Plant bugs (includ— 0.15 tbls
ing tarnished actual*/gal
plant bug) (3% WP)
INBPAUA Rose chafer or
INAMCLA Rose leaf beetle 0.09 oz/gal
IMOAAAA Thrips (9% WP)
or
0. 05—0. 08
tbla actu—
a l*/ga l
(1% WP/D)
INAHALA Flatheaded apple— 3 pt 20% Ed RESTRICTED USE PESTICIDE.
tree borer 100 gal Bark application. Apply at 21 day
or intervals from June to August.
1 tbla 20%
EC/gal
(20% EC)
/35 113AA Scotch PIne
/35126AA White Pine
Refer to Austrian Pine.
Refer to Japanese Black Pine.
/35116AA Spruce (including Norway Spruce and
White Spruce)
IRACAAA Aphids 0.25 lb/100 RESTRICTED USE PESTICIDE.
gal Foliar application. Apply when new
(25% wP) growth is about 2 inches long, be-
fore leaves curl. Repeat as needed.
Issued: 6—05—84 111—009001—81
125
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EPA Index to Pesticide Chemicals
IRAVACA
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Spruce gall adel—
gids (including
cooley 8pruce gall
adelgid)
0.3-0.4 lb/
100 gal
or
0.05 oz**/gal
(1.7 lb/gal
EC)
(20% EC)***
RESTRICTED USE PESTICIDE.
Bark application. Spray trunks and
branches of growing trees June 1 and
again about August 1.
RESTRICTED USE PESTICIDE.
Delayed dormant application. Apply
April 1 to 15 before bud swell and
again in early May when temperature8
increase and before the white cot-
tony egg masses appear. Avoid
spraying trees when there is a dan-
ger of freezing before spray has
dried on tree. Use a spreader
sticker.
INASDBA
White pine weevil
0.1 oz**/gal
(1.63 lb/gal
EC)
or
5 tsp 12.5%
EC/gal
(12.5% EC)
or
3—4 Pt 20%
EC/100 gal
or
1—1.33 tbls
20% EC/gal
(20% EC)
RESTRICTED USE PESTICIDE.
Delayed dormant application. Apply
thoroughly to entire tree covering
terminals. In Northeastern United
States apply in late April when buds
swell. Consult your State Agricul-
tural Extension Service for timing
in other areas.
I 35 119AA
Sycamore
4.5 tbls 5%
EC/gal
(5% EC)
or
I tbls 20%
EC/gal
(20% EC)
Delayed dormant application. Apply
thoroughly to entire tree in late
April when buds swell.
Refer to Beech.
Refer to Boxelder cluster.
Refer to Hawthorne.
Issued: 6—05—84
111—009001—82
Site and Pest
INBQAAA
Dosages and Tolerance, Use, Limitations
Formulation(s )
Bark beetles
Spruce (including Norway Spruce and White Spruce) (continued)
0.7 oz/gal
(1.7 lb/gal
EC)
126
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF .BENZENE IIEXACHLORIDE)
Site and Pest
Dosages and
Forniulation( a )
Tolerance, Use, Limitations
/31205DA
/ 3111 IAA
/ 31111 DA
Tulips
0.1 lb/40 gal
(6% Wi ’)
(1.63 lb/gal
EC)
or
1 pt 10.68%
EC/40 gal
(10.68% EC)
or
2.4 tsp
10.68% Ed
gal
(10.68% EC)
OL
5 tsp 12.5%
EC/gal
(12.57. BC)
or
1 tbls 20%
EC/gal
(20% EC)
/35128AA
Willow
Issued: 6—05—84
Refer to Aspen.
Refer to Beech.
Refer to Boxelder cluster.
Refer to Cottonwood.
111—009001—83
IRACAAA
IOBJAFA
ITBMCCA
ITBCBUA
IMOAAAA
Aphids
Bulb flies
European corn borer
Iris borer
Th rips
RESTRICTED USE PESTICIDE.
Bulb application. Apply as a spray
when pests first appear and repeat
as needed.
127
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE>
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
GREENHOUSE FOOD CROP
( Agricultural Crops )
/ 100 IOCA Cucumber 3 ppm
/l]OO5CA Tomato I day preharvest interval through
/13020CA 1.5 ounces per 50,000 cubic feet for
fog application to greenhouse grown
plants.
Fog application to greenhou8e grown
plants. Place fumigators in single
row on the central walk. Space
evenly for uniform distribution of
smoke. Close all ventilators,
doors, and other openings. Starting
with fumigator at farthest end of
greenhouse away from exit, light
sparkler at handle end and insert
into top half inch of contents.
Proceed to next fumigator until last
fumigator is ignited and evacuate
building. Allow greenhouse to re-
main closed for a minimum of 4
hours. Thoroughly ventilate before
reentry. Ventilate gradually, pre—
ferrably within 8 hours, especially
when plants are in bloom or when
growth is unusually soft. Cloudy
day, late afternoon, or night fumi-
gations at 60 to 80 F (15.5 to 26.7
C) is optimal. Avoid fumigation
when windy or in the presence of
excessive moisture. Repeat as
needed. Do not remain in greenhouse
during fumigation without wearing a
full—face gas mask of a type passed
by United States Department of Agri-
culture for lindane protection and
protective clothing to minimise the
danger of absorption of vaporized
material through skin.
3 ppm
5 day preharvest interval through
1.5 ounces per 50,000 cubic feet for
fog application t o greenhouse grown
plants.
Issued: 6—05—84 111—009001—84
1.5 ozfSO,000
Cu. ft
(2.3%, 5.6%,
11.2% Impr)
I RACAAA
IVABAAA
ETAAALJ
IRABAAJ
/13 O2OCA
Aphids
Grasshoppers
Leaftiers (adults)
Whitefl.ies (adults)
Lettuce
Refer to Cucumber cluster.
128
-------
EPA Index to Pesticide Chemicals
LINDANE (GA iA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest
Tomato
Dosages and
Formulation(s )
Tolerance, Use, Limitations
See Cucumber cluster.
GREENHOUSE NON—FOOD CROP
( Ornamental Plants and Forest Trees )
Ornamental Plants (including
Azalea, Catuellia, Carnation,
Chrysanthemum, Gardenia,
Geranium, Gladiolus, Primrose,
Rhododendron, Rose, and Snap-
dragon)
Aphids
Armyworm
Diabrotica beetles
Flea beetles (in-
cluding larvae)
Grasshoppers
Lace bugs
Leafminers (includ-
ing chrysanthemum
leaf miner )
Leaf rollers
Leaftiers (adults)
Loopers (including
cabbage looper)
Plant bugs (includ-
ing tarnished
plant bug)
Psyllas
Th rips
White f lies
Issued: 6—05—84
Fog application to greenhouse grown
plants. Place fumigators in single
row on the central walk. Space
evenly for uniform distribution of
smoke. Close all ventilators,
doors, and other openings. Starting
with fumigator at farthest end of
greenhouse away from exit, light
sparkler at handle end and insert
into top half inch of contents.
Proceed to next fumigator until last
fumigator is ignited and evacuate
building. Allow greenhouse to re-
main closed for a minimum of 4
hours. Thoroughly ventilate before
reentry. Ventilate gradually, pre—
ferrably within 8 hours, especially
when plants are in bloom or when
growth is unusually soft. Cut wide
open blooms before fumigation.
Cloudy day, late afternoon, or night
fumigations at 60 to 80 F (15.5 to
26.7 C) is optimal. Avoid fumiga-
tion when windy or in the presence
of excessive moisture. Repeat as
needed. Do not remain in greenhouse
during fumigation without wearing a
full—face gas mask of a type passed
by United States Department of Agri-
culture for lindane protection and
protective clothing to minimize the
danger of absorption of vaporized
material through skin.
111—009001—85
129
/32000CA
I RACAAA
ITBCCFA
INAMB IA
INAMADA
IVABAAA
IQAXAAA
IMAAACA
IMAAAEA
ITAAALJ
ITAAAOA
IQAMAAA
IRAXAPA
IMOAAAA
I RABAM
1.5 oz/50,000
Cu. ft
(2.3%, 5.6%,
11.2% Impr)
-------
EPA Index to Pesticide Chemicals
- LINDANE (CANNA ISOMER OF. BENZENE REXACHLORIDE).
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Ornamental Plants (continued)
0.2 lb/l0O
gal
(1.7 lb/gal
EC)
1 Pt 20% Ed
100 gal
1 tsp 20% Ed
gal
(20% EC)
6 fl.o 30%,
40% FIC/l0O
gal
(30%, 40%
F 1C)
2.5 pt 10%
ECJ100 gal
or
1 tbls 10%
EC/gal
(10% EC)
0.25 Pt 40%
EC/l00 gal
(40% EC)
16 fl.oz 2%
RTU/50, 000
cu. ft
(2% RTU)
RESTRICTED USE PESTICIDE.
Application to greenhouse grown
plants. Repeat as needed.
Application to greenhouse grown
plants. Repeat at 7 to 10 day in-
tervals or as needed.
Fog application to greenhouse grown
plants. Close all doors, windows,
and ventilators. Lock or barricade
all entrances, post warning signs,
and take precautioni to prevent en-
try to the treated area. Turn off
all misting systems. Be certain all
blossoms and foliage are dry. A
room temperature of 70 to 85 F (21.1
to 29.4 C) is optimal. Wear a full—
faced gas mask with canister type
recommended by the United States
Department of Agriculture for phoa—
phate insecticide protection. Open
the metering valve on the applicator
to the Number 4 setting on the dial.
Eight ounces of liquid will be tog—
ged per minute with a median diame-
ter size of 5 microns. Start the
or
or
or
or
Issued: 6—05—84
111—009001—86
130
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EPA Index to Pesticide Chemicals
LINDANE (CANMA ISOMER OF BENZENE HEXACHLORIDE)’
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Ornamental Plants (continued)
16.67 fl.oz
5% RTU/
50,000 cu.ft
(5% RTU)
pulsating jet engine of the applica-
tor and allow it to run 1 full min-
ute before opening the insecticide
valve. Walk backward down the en-
tire length of the center aisle of
the greenhouse, directing the fog
over plants. Sway the machine back
and forth, blanketing 2 benches from
each side of aisle. Keep the nozzle
a minimum of 4 feet from the plants.
The applicator should constantly be
moving so as to cover the entire
area as uniformly as possible. Do
not over—apply to the point where
the foliage is visibly vet. Where
bench chrysanthemum, rose and other
plants of such height where it is
difficult to fog over the plants
without wetting the foliage, direct
the fog under the benches. Sway the
machine back and forth, occasionally
pointing the nozzle upward where
possible. Repeat as needed. Allow
a 1.5 hour exposure period. Thor-
oughly ventilate, at least 1 hour,
before reentry. Damage may result
with longer exposure periods.
Fog application to greenhouse grown
plants.
Applicators must wear the following
protective clothing during the ap-
plication process: a light—weight
protective suit or coveralls; water—
resistant hat; unlined, waterproof
gloves; and unlined, light—weight
boots.
Applicators must wear a pesticide
respirator jointly approved by the
Mine Safety and Health Administra-
tion and by the National Institute
for Occupational Safety and Health
under the provisions of 30 CFR Part
11.
Close all windows, doors, and yen—
tilators. Take all precautions ne-
cessary to prevent unprotected per—
Issued: 6—05—84
111—009001—87
131
-------
EPA Index to Pesticide Chemicals
LINDANE (GANMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Ornamental Plants (continued)
FORESTRY
sons from entering the treated area.
To avoid damage to plants, do not
fog greenhouses when the inside tem-
perature exceeds 80 F (26.7 C) or
under conditions of high humidity
or when blossoms or foliage are wet.
Adjust the metering valve or orifice
size in the formulation line to pro-
duce a dry fog. Never apply a wet
fog. A flow rate of 8 fluid ounces
per minute is optimal. Start fog-
ging at I end of the greenhouse and
walk down the center aisle continu-
ously moving away from the fog. Do
not over—apply to the point where
foliage is visibly wet. The green-
house should remain closed for 1.5
hours after fogging.
Formulated with malathion.
( Ornamental Plants and Fore8t Trees )
/30090AA
Forest Trees
Do not apply during rainfall or on
wet bark.
Issued: 6—05—84
1.8 lb/l0O
gal light
petroleum
oil
(1 lb/gal EC)
RESTRICTED USE PESTICIDE.
Bark application. Apply to the bas-
al 18 inches of the trunk, higher
if infestation is present. Allow
spray to run freely down the bark,
using small droplet spray (not mist)
after loose bark is sloughed off.
Also spray stumps as a precaution.
Spray is residual for approximately
3 months.
RESTRICTED USE PESTICIDE.
Bark application. Cut and remove
or spray high risk or beetle infest-
ed trees. Burn or spray tops. Ob-
serve fire daniagea trees regularly.
If inner bark has turned brown, sal-
vage the tree at once. Apply to
trunk, top8, and stumps as a medium
111—009001—88
IN b jAZA
INBQBZA
INBQBAA
INBQB IA
INBQAOA
1.1—1.2 oz’ /
gal diesel
oil
(1, 1.6 lb/
gal EC)
Black turpentine
beetle
Pine beetles
Red turpentine
beetle
Pine engraver
Southern pine
beetle
132
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF. BENZENE HEXACILLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Forniulation( 8)
Forest Trees (continued)
fine spray to the point of runoff.
A mist spray is not desirable. Do
not apply on wet bark. Spray is
residual for approximately 3 months.
/30059AA Pine (Forest)
INBQAZA Black turpentine 0.5 oz/gal RESTRICTED USE PESTICIDE.
beetle no. 2 fuel Bark application. Apply lower rate
INBQBAA Red turpentine oil as a preventative spray and higher
beetle or rate for control of existing infes—
1 oz/ga]. no. tations. Apply to the bark surface
2 fuel oil of the trunk up to a height of 6
(1 lb/gal EC) feet. On uninfe8ted trees to pre-
vent infestation, apply only to the
basal 30 inches of trunk. Slough
off loose or flaky bark and debris
before application. Use a cone—
shaped spray nozzle, producing a
coarse spray and high enough pres-
sure to force spray into cracks and
crevices of bark. Apply to the
point of runoff, approximately 1
gallon of finished spray per 40 to
50 square feet of bark surface. Do
not apply more often than once every
6 months.
Issued: 6—05—84 111—009001—89
133
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest
sand
Formulation(s )
Tolerartee, Use, Limitations
DOMESTIC OUTDOOR
( Household )
/630030A
Domestic Dwellings, Outdoor
Do not allow children or pets in
treated area until all spray has
dried or material washed in.
ISASAAA
ILAWAAA
IOAAAAA
IOAAAFA
IOAMAAA
I LAAACA
Ants
Chigger mites
Flies
Gnats
Mosquitoes
Ticks
0.022 oz/gal
(0.36 lb/gal
EC)
or
3—4 tsp 5%
EC/gal
[ 2.85 gall
100 sq.ft]
(5% EC)
Issued: 6—05—84
4 tbls 4.6%
EC/gal
(4.6% EC)
0.4—1 lb/l0O
gal
(6%, 25% wP)
(1.6, 1.63
lb/gal EC)
(10%, 11.14%,
12.5% EC)#
0.4—0.5 lb/100
gal
[ 40 gal/5,00 0
sq.ft]
(6% WP)
Outdoor treatment. Apply with a
hose end proportioner. Spray all
patio surfaces and surrounding areas
1 to 3 hours before starting cook-
out.
Formulated with naked.
Application to lawns and vegetation.
Apply to weeds, lawns, shrubs, and
underbrush harbouring pests. Repeat
as needed. Do not apply to food
crops.
III—00900190
ISA SAAA
IQAUACA
ILAWAAA
ILAVABA
INBQABA
IOAAAAA
IOA.MAAA
IKAAAAA
ILAAACA
Ants
Boxelder bug
Chigger mites
Clover mite
Elm bark beetle
Flies
Mosquitoes
Spiders
Ticks
1—3 tbls
4.6% 5%
EC/gal
(4.6%, 5%
EC)
Outdoor treatment. Apply to lawns,
soil around buildings, foundations,
along fences and other areas where
pests hide.
May be formulated with naled or
dicofol, inethoxychlor, and malathi-
on.
Outdoor treatment. Apply to all
pest—hiding places in shrubs, lawns,
porches, patios and exterior of
homes.
May be formulated with dicofol,
methoxychior, and malathion.
ILAWAAA
ILAAACA
Chigger mites
Ticks
or
or
134
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OE BENZENE HEXACHLORIDE).
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Domestic Dwellings, Outdoor (continued)
0.1—0.125 lb/
5,000 sq.ft
(1% D)
(25% WP)
or
0.23 lb/5,000
sq. ft
(6% WP)
/630030A Military Buildings, Outdoor
Fleas 0.05 lb/5,000 Use limited to military personnel.
sq.ft Outdoor treatment.
(1% D)
INDOOR
( Processed or Manufactured Products, and Food or Feed Containers or
Dispensers)
General Warnings and Limitations : Observe respirator precaution.
Residual spray or fog application
to empty storage areas. Apply to
the point of runoff by continuous
mechanical fogging, power, or hand—
spraying. Stir the exposed stages
to increase mobile activity. A
coarse spray will soak walls, or
sides of bins, tanks, and jack—
walls. A heavy dense fog will pen-
etrate cracks, crevices, and coat
ledges, joints, guys, cross—beams,
pillars, columns, trusses, walls,
overheads, and bulkheads. Clean
areas thoroughly prior to applica-
tion. Use in conjunction with grain
bin fumigation.
Formulated with methoxychlor.
Issued: 6—05—84 111—009001—91
IMNAAAA
/460280A Food/Feed Storage Areas — Empty
ITAMASA
INBVACA
INATAFA
I NBUATA
INASDQA
ITBMCHA
INAEAEA
INBUASA
I NASDRA
Angouinois grain
moth
Cadelle
Carpet beetle
Confused flour
beetle
Granary weevil
Indianmeal moth
Lesser grain borer
Red flour beetle
Rice weevil
0.5% spray
(25% wP)
or
1.25 gal 0.5%
RTUJ1, 000
sq. ft
[ spray]
or
1 gal 0.5%
RTU/ 10,000
sq.ft
[ fog]
(0.5% RTU)
135
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and
Formulation(s )
/460150A Grain/Cereal/Flour Bins Feed/Food
— Empty
Angoumois grain
moth
Bean weevil
Black carpet beetle
Cockroaches
Confused flour
beetle
Flies
Granary weevil
Indianmeal moth
Rice weevil
Sawtoothed grain
beetle
Silverfish
Empty bin spray. Clean bin prior
to spraying. Apply to places wttere
insects hide and breed, paying par-
ticular attention to cracks and
crevices in walls, windows, doors,
floors and empty bins. Use in con-
junction with grain fumigation. Ap-
ply prior to bin filling.
/5300lIA
/53002 1A
/53006 1A
/53005 1A
/53003 1A
( Pets and Domestic Animals)
( Animals and Their Man—Made Premises)
Beef Cattle
Goats
Hogs
Sheep
7 ppm (fat of meat)
30 day pre—slaughter interval
through 0.06 percent spray.
60 day pre—slaughter interval
through 0.06 percent dip.
RESTRICTED USE PESTICIDE.
Do not treat animals under 3 months
of age. Young animals between 3 and
6 months of age may not be treated
with concentrations greater than
0.03 percent. Do not treat sows
within 14 days of farrowing nor for
a minimum of 21 days thereafter.
Do not treat animals in cold, stormy
weather. Do not treat overheated
or sick animals. Make sure animals
are well watered prior to being
dipped to prevent them from drinking
the treated dip. When spraying use
a sprayer capable of maintaining
pressure of 200 to 400 pounds per
square inch. Use 1 to 2 gallons of
spray per head for cattle and horses
and proportionally less for smaller
animals. For pressurized sprays
hold can 4 to 8 i’nches from area to
be treated. Release spray for 3 to
10 seconds per wound or infestation
mass.
Issued: 6—05—84
111—009001—92
Tolerance, Use, Limitations
ITAMASA
INAGABA
INATAHA
IVAAABA
INBUATA
IOAAAAA
INASDQA
ITBMCUA
INASDRA
INARAGA
IMP BACA
0.5% spray
(25% WP)
or
0.5% spray
11—2 gal/
1,000 sq.ftl
(1.65 lb/gal
EC)
(20% sc)
136
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HExACHLORIDE)
Site and Pe8t
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Beef Cattle cluster (continued)
Fleas
Itch mite family
Lice
Sheep ked (on sheep
and goats)
Ticks
0.023—0.06%
[ dip or
spray]
(62, 25% WP)
(1%, 25%
WP/D)
(1, 1.6,
1.63, 1.65,
1.75 lb/gal
BC)
(22, 6.5%,
10%, 10.68%,
11%, 11.14%,
12.5%, 20%
EC)
(1% FIC)
Animal dip or spray treatment.
Thoroughly wet the animal. For
chorioptic manage mite complex, itch
mite family and the scab mite family
make 2 applications at 7 to 14 day
intervals. If spray treatment is
used, spray thoroughly to get under
the scabs. Animals’ quarters should
also be sprayed. For sheep ked ,
when spraying, spray along the back,
around the ears, and spray against
the wool. Spray in the fall. In
some areas a repeat spraying may be
needed after shearing. For stable
! this treatment is supplemental
and should be accompanied by premise
treatments.
For other pests apply when pests
appear and repeat at a minimum of 3
day intervals.
Animal dust treatment. Dust thor-
oughly and rub dust into the hair
coat. Repeat at 14 to 30 day inter-
vals. May be used during winter
when a spray is not advised.
Application is supplemental to prem-
ises treatment.
May be formulated with methoxychior
and sulfur.
Animal spray treatment. Thoroughly
spray alt the inner surfaces of the
ear. Use enough spray to wet the
skin and allow a little to run in
the ear. Release spray for 3 sec-
onds per ear when treating cattle
and 2 seconds per ear when treating
smaller animals. Massage to insure
complete coverage. Spray must come
in contact with pest. Repeat as
needed.
Chorioptic mange
mite complex
Fleas
Horn fly
Itch mite family
Lice
Mosqui toe8
Scab mite family
Sheep ked (on sheep
and goats)
(Stable fly)
Ticks
IQALABA
IMNAAAA
IOAUADA
ILASAAA
IMAAADA
I OAMAAA
ILAQAAA
IOATABA
IOAUAHA
ILAAACA
IMNAAAA
ILASAAA
IMAAADA
IOATABA
ILAAACA
ILACADA
(0.5%, 1% D)
(1% WP/D)
Ear tick pressurized
spray
(32 PrL)
Issued: 6—05—84
111—009001—93
137
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENZ HEXACHLORIDE).
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Beef Cattle cluster (continued)
IOAGABA
Fleeceworms/wool
maggots/wound
maggots (on sheep
and goats)
pressurized
spray
(32 PrL)
Animal spray treatment. Spray
directly on infested areas and to a
distance of 2 or 3 inches outside
the infestation. Repeat treatment
2 times every 7 days until infesta-
tion is controlled.
IOAGADA
Screworm
pressurized
spray
(3% PrL)
Animal spray treatment of screwvorm
infestations in superficial cuts or
wounds. Spray directly into and 1
inch around infested wounds. Also
spray drainage area below the wound.
Repeat treatment 2 times every 7
days until wound heals.
Animal spray treatment for protec-
tion against screwworm. Spray all
superficial wounds such as wire cuts
and shear cuts and after docking,
dehorning, or castrating. Repeat
treatment 2 times every 7 days until
wound heals.
/5300 1 1A
/53002 1A
/53005 1A
I LASAAA
ILAQAAA
(Beef Cattle)
(Goats)
(Sheep)
Itch mite family
Scab mite family
1.25 gal
0.45%,
1.96%, 2.5%
EC/l0O gal
(0.45%,
1.96%, 2.5%
EC)
Animal dip or spray treatment.
When dipping allow a minimum of 30
seconds per animal dunking their
heads a minimum of 2 times.
Formulated with toxaphene.
0.83 gal
0.45%,
1.96%, 2.5%
EC/lOO gal
(0.45%
1.96%, 2.52
EC)
Issued: 6—05—84
111—009001—94
Dip replenishment. Maintain a pre—
mixed emulsion in a clean 30 to 55
gallon overhead drum.
Formulated with toxaphene.
138
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF. BENZENE HEXACRLORIDE)
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Beef Cattle cluster (continued)
/5300lIA
/530051A
ILASADA
(Beef Cattle)
(Sheep)
Itch mite
1.11 gal 1%
EC/l0O gal
(1% EC)
or
1.33 gal 2%
EC/lOO gal
(2% EC)
and submerge each
When spraying use
quarts of finished
for beef cattle and
less for sheep. Re—
if reinfestation
toxaphene.
/5300lIA
/53006 1A
ILASAAA
IMAAADA
ILAMCA
(Beef Cattle)
(Hogs)
Itch mite family
Lice
Ticks
Dust bag
(1% D)
Animal dust bag treatment.
0.22 solution
mixed with
no. 2 fuel
oil
[ 1 ga1/1O— O
linear ft of
back rubber]
(1.63 lb/gal
EC)
0.2% RTU
(0.22 RTU)
Animal back rubber treatment. Treat
burlap wrapped cable at 21 to 28 day
intervals. Do not make back rubber
accessible to beef cattle within 30
days of slaughter or animals under
6’ months of age.
Hog oiler or rubbing post treatment.
Pour on a post wrapped with rope or
burlap.
Animal sponge treatment. Sponge
infected areas. Use 1 tablespoon
25 percent wettable powder for young
calves 3 to 6 months old. Repeat
at 7 to 10 day intervals.
ILACADA
IOAUADA
IOAGADA
ILAAACA
Ear tick
Horn fly
Sc reworm
Ticks
Issued: 6—05—84
10 fl.oz 302,
40% F1C/100
gal
(302, 40%
FIC)
111—009001—95
Animal dip or spray treatment. When
dipping allow a minimum of 30 sec-
onds per animal
animal 2 times.
approximately 3
spray per head
proportionally
peat in 21 days
occurs.
Formulated with
IMAAADA
IQA LA BA
ILASAAA
Lice
Chorioptic mange
mite complex
Itch mite family
0.25—0.5 tbls
actua l*/gal
(25% WP)
Animal dip or spray treatment.
139
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE REXACHLORIDEY
/54003 1A
Site and Pest
Dogs
Dosages and
Formulation(s )
Tolerance, Use, Limitations
RESTRICTED USE PESTICIDE.
Do not treat animals within 30 days
prior to giving birth to young. Do
not treat nursing animals. Do not
treat dogs less than 4 months old.
ILASAAA
Itch mite family
0.032—0.046
oz/gal
(6% wP)
(1.65 lb/gal
EC)
or
0.1—0.25 tbls
actual*/gal.
(6.5%, 8.82%,
10.94%,
12.2%,
12.89%, 20%
EC)
Animal treatment. Apply as a spray,
dip, or using a sponge or brush.
Thoroughly wet the dog with the
dilution making sure that mange
scabs and lesions are penetrated.
Allow the dog to dry in a warm place
without rinsing or toweling.
OR MAI
Formulated with carbaryl or malathi-
on; pine oil; or pine oil, piperonyl
butoxide, technical, pyrethins, and
poly(oxyethylene) sorbitol mixed
ether ester.
--OR MAI--
1.5 fl.oz
0.425% Ed
gal
(0.425% EC)
or
2 fl.oz 2%
EC/gal
(2% Ed)
or
8 tsp 3.9%
EC/gal
(3.9% EC)
or
5 tsp 5% Ed
gal
(52 EC)
Animal treatment. Cleanse infected
area with antiseptic soap, let dry
and gently massage lotion over in-
fected area. If a large area is
involved it should be divided into
separate areas which are treated
alternately ever i other day. Repeat
at 3 to 7 day intervals.
May be formulated with benzyl ben—
topical
(0.1%, 0.5%
RTU)
Issued: 6—05—84
111—009001—96
140
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE>
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Dogs (continued)
zoate, rotenone or benzyl benzoate
and rotenone.
IMNAAAA Fleas shampoo Animal treatment. Thoroughly wet
ILASAAA Itch mite family (0.05%, the entire hair coat and apply
IMAAADA Lice 0.097%, enough shampoo to make a lather.
ILAAACA Ticks 0.25%, Work thoroughly into the hair coat.
0.3% RTU) Allow the lather to remain in con-
tact with the skin for a minimum of
5 minutes before rinsing. Rinse
thoroughly. Repeat as needed, but
not more than once every 7 days.
May be formulated with potassium
tetrathionate or piperonyl butoxide,
technical and pyrethrins.
Refer to Fox for additional use and limitation
information.
/5lOl OIA Fox
/54003 1A —
IMNAAAA Fleas —— Animal dust treatment. Dust powder
IMAMDA Lice (0.5% D) well into the hair coat, particular
ILAAACA Ticks ly along the back line from the base
of the tail to the head. Use in
conjunction with premises treatment.
May be formulated with methoxychlOr ,
technical and sulfur.
/53003 1A Horses 7 ppm (fat of meat)
RESTRICTED USE PESTICIDE.
Refer to Beef Cattle cluster and Mules for use and
limitation informatiOn.
/56006 1A Mules
/53003 1A
IMAAADA Lice Animal dust treatment. Thoroughly
(1% D) dust the hair coat of the animal,
but do not rub in.
Issued: 60584 III00900 197
141
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF• BENZENE HEXACHLORIDE)
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
/ 5400 3JA
ISASAAA
IVAAABA
IMNAAAA
I OAAAAA
IMAAADA
IOAMAAA
ILAAACA
Mules (continued)
Screwworm topical
(3% RTU)
Ants
Cockroaches
Fleas
Flies
Lice
Mites
Mosquitoes
Ticks
4 tbls 20%
EC/gal
(20% EC)
1 part 20%
EC/9 parts
water
(20% EC)
Animal treatment. Apply using a
swab or soft bristle brush. Apply
thoroughly to all wounds making sure
it covers all blood and exudate in
the wound area. Repeat 2 times
every 7 days.
Animal premise treatment. Dust
kennels, hutches, bedding or litter.
Repeat when necessary. Use limited
to population reduction.
May be formulated with methoxychior
and sulfur.
Fleas 3 fl.oz
12.89% EC/
ga 1
(12.89% EC)
Garbage Dumps (livestock premises)
Livestock Premises (manure treat—
men t )
Flies 0.125% spray
(11.14% EC)
Premix treatment. Saturate surfaces
such as houses, fencing, cement
runs, and surrounding grounds to the
point of runoff.
1 ppm (fat of meat)
Do not apply treated manure to land
to be planted to root crops. Use
limited to population reduction.
Wet thoroughly every 21 to 28 days
or as manure is added.
IOACADA
/54003JA
/ 5101 OJA
IMNAAAA
IMAAADA
(Animal Premises)
Dog Kennels
Fox Hutches
(Fleas)
(Lice)
(Dog Kennels)
(0.5% D)
Premises treatment. Apply as a
coarse spray to kennel walls, and
cracks and crevices.
Residual paint. Apply to windows,
doors, and other places where
pests congregate.
IMNAAAA
/890030A
/ 5 2000KA
IOAAAAA
Issued: 6—05—84
I 11—009001—98
142
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE).
and
Formulat ion(s )
0.1 lb/1,000
sq.ft
(1% D)
0.05 lb/1,000
sq.ft
(1% D)
1 ppm (fat of meat)
Premise treatment. Remove soiled
bedding or litter and apply to the
floor or ground area. Provide clean
bedding or litter.
Premise treatment. Scatter on the
bedding occasionally as a preventa-
tive measure.
/52000JA
/61000JA
Livestock Building and Pens
1 ppm (fat of meat)
Do not use in dairy barns or poul-
try houses. Cover feed and water
troughs before spraying or wash
thoroughly with a pressure hose
before spray deposit dries. Remove
animals prior to application.
I SASAAA
IQAFAAA
IVAAABA
IMNA.AAA
IOAAAAA
IOAAAFA
IOAKAAA
IOAMAAA
IMP BACA
IKAAAAA
ILAAACA
Ants
Bed bug complex
Cockroaches
Fleas
Flies (including
house fly and
stable fly)
Gnats
Midges
Mosquitoes
Silverfish
Spiders
Ticks
Issued: 6—05—84
0. 1—0.3%
spray
[ 1—2 gall
1,000 sq.ft)
or
0.3—0.5% _______
spray
[ 1 gal/l000
sq. ft
(6%, 25% WP)
(25% WP/D)
(1, 1.6,
1.63, 1.75
lb/gal EC)
(6.5%, 10%,
10.68%,
11.14%,
12.5%, 20%
40% EC)
(20% sc/L)
(40% FIC)
111—009001—99
Site and Pest
/53006JA Hog Pens
IMNAAAA
IMAAADA
(Fleas)
(Lice)
Tolerance, Use, Limitations
Residual premise treatment. For
crawling insects thoroughly spray
all baseboards, cracks, floors, and
other places where pests hide, also
spray any pests present. For flying
insects apply as a coarse spray to
ifls, ceilings, beams, screens,
window frames, partitions, and sim-
ilar places where pests congregate.
Repeat as needed. Applications may
be made. o interior or exterior sur-
faces, adjacent fences, and weedy
foliage. Do not allow livestock to
graze treated foliage.
The 20 percent solution conceatrate/
liquid is diluted in odorless kero-
sene.
I43
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Livestock Building and Pens (continued)
1.25% paint
(25% WP)
(1.6, 1.63
lb/gal EC)
(10.63%,
11.14%,
12.5%, 20%
EC)
Residual paint. Apply as a paint
around windows, doors, ceiling
beams, window screens and on base-
boards and in cracks. Repeat as
needed. This concentration may
blister painted surfaces.
( Agricultural Premises and Equipment )
/61000JA
Agricultural Premises
( Household )
Refer to (Pets and Domestic Animals) (Animals and
Their Man—Made Premises), Livestock Buildings and
Pens for use information.
/630070A
Domestic Dwellings
Contents
Bed bug 1% spray
(20% EC)
(1.63 lb/gal
Sc / L)
Apply lightly but thoroughly to
beds, mattresses, and other hiding
places about the room. Direct the
spray into all cracks and crevices
and around baseboards, walls, and
floors.
ITBSABA
Clothes moths
0.1% spray
(1.63 lb/gal
sc/L)
Moth proofing treatment. Apply
lightly but thoroughly to infested
areas on clothing and bedding. Pay
special attention to folds and
seams. Repeat at 30 day intervals
as needed.
0.5% spray
(20% EC)
(1.63 lb/gal
SC/L)
Moth proofing treatment. Apply to
materials immediately being prepared
for storage. Dry clean before using
articles.
IQAFACA
Issued: 6—05—84
I 11—009001—100
144
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF• BENZENE HEXACHLORIDE)
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
/630010A
Domestic Dwellings, Indoor
Do not allow children or pets in
treated area until all spray has
dried.
ISA SAAA
IVAAABA
IOAAAAA
ITAAABA
IMP BACA
Ants
Cockroaches
Flies
Moths
Silverfish
dust
(0.5% D)
or
0.4—0.5%
paint or
spray
(0.5%, 20%
EC)
(1.63 lb/gal
SC/L)
or
pray
(0.5% RTU)
or
pressurized
spray
(0.25% PrL)
0.5% spray
(20% EC)
or
spray
(0.5% RTU)
or
pressurized
spray
(252 PrL)
Indoor treatment. Apply where pests
hide contacting as many as possible
with dust or spray. For ants apply
to ant trails and areas where they
enter the house. All door sills,
window frames, water pipes, heat
ducts, electrical outlets and base-
boards. For carpet beetles make a
localized application to floor base-
boards, into cracks and crevices,
and under carpets. For cockroaches
apply to cracks and crevices.
May be formulated with methoxychior,
naled, or uiethoxychlor and sulfur,
or dicofol, methoxychlor, and mala—
th ion.
shelf paper
15—19 mgI
sq. ft
(0.272 lmpr)
Nonfood areas only. Line drawers,
shelves, cabinets, storage areas,
particularly those around garbage
containers, under sinks, in broom
closets, basements, and all secluded
damp areas where pests congregate.
Leave some paper surface exposed so
pests may contact treated paper.
Reline a minimum of 2 times per
year.
I SASAAA
INATAFA
IVAAABA
IMP BACA
IKAAAAA
IOAAAAA
IOAAAFA
I OAMAAA
Ants
Carpet beetle
Cockroaches
(including Ameri-
can and Oriental
cockroaches)
Silverfish
Spiders
Flies
Gnats
Mosquitoes
Issued: 6—05—84
0.1% spray
(1.63 lb/gal
SC/L)
Indoor space spray. Apply
conventional mist sprayer.
area closed for 10 minutes.
late prior to reentry.
with a
Leave
Venti—
Indoor spray. Apply as a spot
spray to wall surfaces, around
doors, screens, and areas where
pests alight.
May be formulated with methoxychlor,
or naled.
111—009001—101
145
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF. BENZENE HEXACHLORIDE)
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, LimitatiOnS
( Wood or Wood Structure Protection Treatments )
IMAAACA
Wood boring insects
brush on or
spray
[ 1 gal 0.5%
100—200
sq.ft)
(0.5% EC)
(1% RTU)
(0.75% PrL)
Non8oil contact nonfumigation treat-
ment. For wood surfaces that have
been painted or varnished. Brush
on or apply as a coarse spray and
make repeated applications as the
chemical is absorbed. If possible
locate the exit holes to the termite
galleries, enlarge it with a needle
or ice pick, and inject into the
hole with a pressure oil can or a
hypodermic syringe. If possible
remove the object to be treated out-
doors or treat in a well ventilated
room. Leave area closed up for
several hours or until the wood has
thoroughly absorbed the solution.
Formulated with orthodichlorO
benzene.
Nonsoil contact nonfumigatiOn treat-
ment. Treat surfaces or treat
flight holes.
/640000A
Terrestrial Structures
RESTRICTED USE PESTICIDE.
0.5% paint
spray
(1, 1.6,
1.63 lb/gal
EC)
(12.5% EC)
Powderpost beetles I gal 0.5%
RTU/ 100
sq.ft
(0.5% RTU)
Issued: 6—05—84
or Nonsoil contact wood protection
treatment. For small areas brush
on infested areas. For large or
overhead areas apply as a coarse
wet spray but not to the point of
runoff. Do not apply as a mist.
Nonsoil contact fumigation treat-
ment. For infestations in joists,
sub—floors, and other structural
timbers. Spray thoroughly to the
point of runoff on lumber 2 inchea
or less in thickness. Repeat ap-
plication in 14 to 30 days. If in-
festation is found in thicker lumber
(girders, beams), pressure impreg-
nation of these timbers is required.
For infestations in flooring, hard-
wood paneling or trim apply to the
surface, after removal of all wax.
iII—00900 1102
/640030A Finished Wood Products
IMGCAGA
INAAACA
IMGCABA
Dryvood termites
Powderpost beetles
Powderpost termites
INALAAA
INBEAAA
INBEAAA
I NAAACA
Cerambycid beetles
Deathwatch beetle
family
Lyctid beetle
146
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EPA Index to Pesticide Chemicals
LIIJDANE (GA}O&h ISOMER QF ENZENE LiEXACHLORIDE)
Pest Dosages and ToLersnce Use, Li itatiO S
Formulation(s)
terrestria l _ StruCt9r ! (continued)
Ventilate and re—IJaX after 24 boats.
Repeat appitcattolt in £4 to SO days.
Acoid seepage through floor cracks
if floor is laid in asphalt mastic
on concrete slabs or laid ovet tar
or asphalt building paper as asphalt
bleeding may result.
U ICDAWs Sithterratteafl t t O.6 emulsion Soil contact wood protection treat—
mites (incLuding (1 lb/gal EL) nent.
Coptoter uLs and Use limited to professionaL pest
Retictiltterni s control operators. This formtlattca
is designed for treatment of soil
to esca jlish a barrtet nth is
lethal to termites. Lit\datlM must
be adequately dispersed in the soil
to provide a barrier between the
ia the stttc.ure s i x. If-.2 ts r —
mite colonies in the soil dr to
ccttitrol termites li’dng in the
structure.
It is ae:es LTi ±or :he effective
US€ of lindanc that the servtce
technician be familiar with current
control practices including trenc r
ing rodding, substab injection, end
low pressure spray application.
These techniques nt%St be correctly
employed to prevent or control in—
featatiotta y subterrttlea termite
species of heterotermes and Reti-
cuterres. ChoicE of appropriate
procedures incLndes coesiderat icA
of such variable factors as the
design. of the structure, water
table, soil type, soil compactiOfl 1
grade conditions and location and
type of domestic water supplies.
The biology and behavior of the
involved termite speciCa are impor-
tant factors to be known as well as
suspected location of the colony and
severity of the infestation within
tt e structure to be protected. flit
advice coucerning current control
practices for specific local condI
tions, consult resources in sttUC-
ture! past control. Annual Lnspec
tasued: 6—05—84 in—009 00t— 10 3
147
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OE BENZENE UEXACHL0RIDE),
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Terrestrial Structures (continued)
tions of the treated area should be
made. Retre.atment may be nece8sary
if there is an active infestation
or if there has been a disruption
of the chemical barrier in the soil
due to construction, excavations,
landscaping, etc. Soil should not
be treated when excessively wet.
The termites’ source of moisture
should be eliminated by providing a
chemical barrier and/or repairing
faulty construction. Contamination
of public and private water supplies
must be avoided by following these
precautjons Use antiback—flow
equipment or procedures to prevent
syphonage of pesticide back into
water supplies. Do not treat soil
that is water saturated or frozen.
Consult state and local specifica-
tions for recommended distances of
treatment areas from wells, and
refer to Federal Housing Adminis-
tration (F.h.A.) Specifications for
further guidance. All nonessential
wood and cellulose containing mate-
rials, including scrap wood and
form boards, should be removed from
around foundation walls, crawl
spaces, and porches.
PRECONSTRUCTION SUBTERRANEAN TERMITE
TREATME NT
Effective preconstructjon subterra-
nean termite control requires the
establishment of an unbroken verti-
cal and/or horizontal chemical bar-
rier between wood in the structure
and the termite colonies in the
soil. To meet F.H.A. termite proof-
ing requirements, follow the latest
edition of the Housing and Urban
Development (1{.U.D.) Minimum Proper-
ty Standards. After grading is com-
pleted and prior to the pouring of
the slab, slab supported/constructed
porches, or entrance platforms, make
the following treatments. Applica—
Issued: 6—05—84 111—009001—104
148
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EPA Index to Pesticide Chemicals
LINDANE (GANM ISOMER OF BENZENE HEXACIILORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Terrestrial Structures (continued)
tions shall be made by a low pres-
sure spray for horizontal barriers
over areas intended for covering
floors, porches, and other critical
areas. Establish a vertical barrier
in areas such as around the base of
foundations, plumbing, back—filled
soil against foundation walls, and
other critical areas.
1. Where it is necessary to produce
a horizontal barrier, apply the
emulsion at the rate of 1 gallon
of 0.8 percent emulsion per 10
square feet to dirt fill. If
fill is washed gravel or other
coarse material, apply at 1.5
gallons of 0.8 percent emulsion
per 10 square feet. It is im-
portant that the emulsion reach-
es the soil substrate.
a. If concrete slabs cannot be
poured over soil the same
day it has been treated, a
waterproof cover, such as
polyethylene sheeting,
should be placed over the
soil. This is not necessary
if foundation walls have
been installed around the
treated soil.
2. To produce a vertical barrier,
apply the emulsion at the rate
of 4 gallons of 0.8 percent
emulsion per 10 linear feet per
foot of depth.
a. Rodding and/or trenching
applications should not be
made below the top of the
footing.
b. Trench need not be wider
than 6 inches.
c. Rod holes should extend from
the base of the trench to
the top of the footing, and
should b spaced (about 1
foot) to provide a continw
ous barrier.
Issued: 6—05—84 111—009001-405
149
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Terrestrial Structures (continued)
d. Emulsion should be mixed
with the soil as it is being
replaced in the trench.
Cover treated soil with a
layer of untreated soil.
3. Hollow block foundations or
voids of masonry should be
treated to make a continuous
chemical barrier in voids. Ap-
ply at the rate of 2 gallons of
0.8 percent emulsion per 10
linear feet so it will reach the
footing.
4. For crawl spaces apply at the
rate of 4 gallons of 0.8 percent
emulsion per 10 linear feet per
foot of depth from grade to
bottom of foundations. Appli-
cation may be made by rodding,
low pressure spray, and/or
trenching. Treat both sides of
foundation and around all piers
and pipes.
a. Rod holes should be spaced
(about 1 foot) to provide a
continuous chemical barrier.
b. Trench need not be wider
than 6 inches nor below the
foundation. The emulsion
should be mixed with the
soil as it is being replaced
in the trench. Cover the
treated soil with a layer
of untreated soil.
c. Do not apply in any manner
to an area intended as a
plenum air space.
d. Do not apply as an overall
treatment to soil in crawl
spaces.
All holes drilled in construction
elements for treatment should be
securely plugged.
POSTCONSTRUCTION TREATMENTS
Postconstruction applications shall
be made by injection, rodding, low
pressure 8pray, and/or trenching.
Issued: 6—05—84 111—009001—106
150
-------
EPA Index to Pesticide Chemicals
LINDANE (GANMA iSOMER 0F BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Terrestrial Structures (continued)
Do not apply emulsion until location
of heat or air conditioning ducts,
vents, water and sewer lines, or
electrical conduits are known and
identified. Extreme caution must
be taken toavoid contamination of
these structural elements and air-
ways. Do not apply in any manner
to an area intended as a plenum air
space.
1. For slab—on—ground construction
apply at the rate of 4 gallons
of 0.8 percent emulsion per 10
linear feet. Application may
be made by subsiab injection.
Injectors should not extend be-
yond the tops of the footings.
Treat along the outside of the
foundation and where necessary
on the inside of foundation
walls. Treatment may also be
required along I side of inte-
rior partitions and along all
cracks and expansion joints.
a. Drill holes in the slab to
provide a continuous chemi
cal barrier.
b. Where necessary, drill
through the foundation walls
from the outside and force
the emulsion just beneath
the slab or along all the
cracks and expansion joints
and other critical areas.
c. For shallow foundations, I
foot or less, dig a narrow
trench approximately 6 inch-
es wide along the outside
of the foundation walls.
Do not dig below the bottom
of the foundation. The
emulsion should be applied
to the trench and the soil
at the rate of 4 gallons of
0.8 perce nt emulsion per 10
linear feet as the soil is
replaced in the trench.
Issued: 6—05—84 III—00900 1 107
151
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF’ BENZENE HEXACHLORIDE) ’
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Terrestrial Structures (continued)
Cover the treated soil with
a layer of untreated soil.
d. For foundations deeper than
1 foot follow rates for
basements.
2. Hollow block foundations or
voids of masonry should be
treated to make a continuous
chemical barrier in voids. Ap-
ply at the rate of 2 gallons of
0.8 percent emulsion per 10
linear feet.
3. For basements apply at the rate
of 4 gallons of 0.8 percent
emulsion per 10 linear feet.
Where footings are greater than
1 foot of depth from the grade
to the bottom of the foundation,
application may be made by
trenching and/or rodding. Treat
outside of foundation walls, and
if necessary along inside of
foundation walls, along cracks
in basement floors, along inte-
rior load bearing walls, around
sewer pipes, conduits, and
piers.
4. In crawl spaces apply at the
rate of 4 gallons of 1 percent
emulsion per 10 linear feet per
foot of depth from grade to
bottom of foundation. Applica-
tion may be made by rodding,
and/or trenching. Treat both
sides of foundation and around
all piers and pipes.
a. Rod holes should be spaced
(about 1 foot) to provide a
continuous chemical barrier.
b. Trench need not be wider
than 6 inches nor below the
foundations. The emulsion
should be mixed with the
soil as it is replaced in
the trendh. Cover the
treated soil with a layer
of untreated soil.
Issued: 6—05—84 111—009001—108
152
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACRLORIDE)
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Terrestrial Structures (continued)
c. Do not apply in any manner
to an area intended as a
plenum air space. After
treatment, securely plug all
holes drilled in construc-
tion elements.
d. Do not apply as an overall
treatment to soil in crawl
spaces.
All holes drilled in construction
elements for treatment should be
securely plugged.
Label claims it will provide resi--
dual control of subterranean ter-
mites for a minimum of 5 years when
used properly.
IMGAAAA
Termites (swarm
prevention)
4 lb 14.64%
RTU/ 1,000
sq.ft
(14.64% RTU)
Soil contact nonfuinigation treat-
ment. Through holes drilled in
concrete slabs inject 45 to 60 days
before regular swarming season be-
gins. Immediately plug holes with
concrete or brass caps.
Formulated with 1,2 ,4—trichloroben
zene.
/ 6400 lOA
Unseasoned Forest Products
RESTRICTED USE PESTICIDE.
INAAABA
Ambrosia beetles
3.6 gal
11.34%,
11.37% Ed
100 gal
water, kero-
sene, diesel
fuel, no. 2
fuel oil
[ 1 gal/IOO
sq.ft of log
surface)
(11.34%,
11.37% EC)
Nonsoil contact nonfumigatiOn treat-
ment. Spray promptly after the
trees have been felled and bucked.
Thoroughly wet all log surfaces,
bark, and ends.
May be tank mixed with pentachloro
phenol.
Issued: 6—0584
III—00900l109
153
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF. BENZENE HEXACHLORIDE)
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Unseasoned Forest Products (continued)
Issued: 6—05—84
0.625 gal
11.34% Ed
100 gal anti
stain mix—
t ure
(11.34% EC)
or
1 gal 11.37%
EC/lO0 gal
dipping or
anti stain
mixture
(11.37% EC)
1.33 gal
6.63% EC/100
gal water
[ 8—10 gall
1,000 board
ft]
(6.63% EC)
3.57 gal
11.34% Ed
100 gal
water, kero-
sene, diesel
fuel, no. 2
fuel oil
[ 0.375—0.5
gal/ 1,000
board ft of
1 inch lum-
ber J
(11.34% EC)
2—5 gal
EC/100
water
[ 8—10 gall
1,000 board
ft I
(6.63% EC)
Nonsoil contact nonfuznigation treat-
ment. Log and lumber dips.
Nonsoil contact nonfumigation treat-
ment. For dipping rough sawn lumber
dried according to industry stan-
dards. Treat within 24 hours of
cutting.
Formulated with tetrachlorophenol
and other chlorophenols.
Nonsoil contact nonfumigation treat-
ment. Lumber may be sprayed prior
to stacking or after the lumber is
in the seasoning stacks. When
spraying stacked lumber apply with
a high pressure spraying equipment
equipped with a nozzle that produces
a fine mist. Direct the spray so
that the mist gets into all air
spaces between lumber in the stack.
Nonsoil contact nonfumigation treat—
iuent. Spray treatment for prolonged
exposure, very susceptible wood
species, or severe conditions, as
in tropical areas.
Formulated with tetrachiorophenol
and other chiorophenols.
111—009001—110
154
INAAABA
INALAQA
Ambrosia beetles
Sawyers
6.63%
gal
-------
EPA Index to Pesticide Chemicals
LINDANE (GANMA ISOMER OF. BENZENE HEXACHLORIDE)
Site and Pest
Dosages and
Formulation(s )
Tolerance ,Uae, Limitations
Unseasoned Forest Products (continued)
5.88 gal
6.63% EC/lOO
gal. water
(6.63% EC)
Nonsoil contact fumigation treat-
ment. Spray treatment for longer
residual control.
Formulated with tetrachiorophenol
and other chlorophenols.
INBQAAA
Bark beetles
1.79 gal
11.34% Ed
100 gal die-
sel fuel or
no. 2 fuel
oil
[ 1 gal/lOO
sq.ft of log
surface]
(11.34% EC)
Nonsoil. contact nonfumigation treat-
ment. Spray treatment. Thoroughly
wet all log surfaces and log ends.
INBEAFA
Lyctus beetles
4 gal 11.37%
EC/100 gal
dipping mix-
ture
(11.37% EC)
Nonsoil contact nonfumigation treat-
ment. Log and lumber dip.
2.7 gal
EC/lOO
water
(8—10
1 000
ft of
ber]
(6.63% EC)
Nonsoil contact nonfumigation treat-
ment. For dipping rough sawn lumber
dried according to industry stan-
dards. Treat within 24 hours of
cutting.
Formulated with tetrachlorophenol
and other chlorophenols.
(Noncrop, Wide Area,
and General Indoor/Outdoor Treatments)
/680000A Wide Area General Indoor/Outdoor
Treatments
Issued: 6—05—84
1 gal 1.68%
EC/4 gal
water, fuel
oil or other
suitable
solvent
(1.68% EC)
Application for municipal reduction
of cockroach populations. Thorough-
ly wet the insides of manholes and
sewage lines. Treat garbage racks,
and garbage cans found in alleys
between buildings. Apply as a
coarse spray and wet garbage dumps
and refuse areas. Repeat as needed.
Formulated with vapona.
tIt—009001—l l l
INALAQA
Sawyers
6.63%
gal
gal /
board
lum-
IVAAABA
Cockroaches
155
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest
Dosages and
Formulation(s )
Tolerance, Use, Limitations
Wide Area General Indoor/Outdoor Treatments (continued)
IOAMAAA
Fleas 0.4 lb/A
(1% D)
Mosquitoes
0.4% spray
[ 5—10 gall
Al
(I lb/gal EC)
(25% EC)
1 gal 1.68%
EC/15 gal
water or
fuel oil
(1.68% EC)
ULV
undiluted
at 0.5 gal
1.68% EC/A
(1.68% EC)
Use limited to military personnel.
Outdoor treatment.
Outdoor treatment. For temporary
control around camp sites and
bivouac areas. Apply lightly to
vegetation, tree trunks, and other
surfaces.
Outdoor treatment. For mites and
ticks , apply per acre rate depending
on amount of vegetation and litter.
For flea control apply at the same
rate to infested grounds and under
buildings.
Outdoor application. Apply so that
the residual deposit will aid in the
control of flies and mosquitoes.
Thoroughly wet the surfaces where
pests alight such as garbage dumps,
refuse heaps, outside of barns and
buildings and undergrowth near stag-
nant water.
Formulated with vapona.
Ultra low volume. Outdoor applica-
tion. Apply with electronic fogging
equipment. Do not apply where food
or feed crops are growing.
Formulated with vapona.
( Comiuercial and Industrial Uses )
/77000JC
Commercial Establiahment8
Issued: 6—05—84
0.3% spray
or
0.5% spray
[ 1.33—2 gall
1,000 sq.ftl
(1 lb/gal EC)
(1.63 lb/gal
SC/L)
(11.14% EC)
Use limited to professional pest
control operators. Indoor residual
spray. Apply the 0.5 percent spray
for a longer residual control. For
crawling insects apply as a spot
spray to cracks, crevices, and other
places where pests hide. For flying
insects limit application to areas
where those pest gather such as
around windows, doors, and light
fixtures. Do not apply as a mist
spray.
111—009001—112
IMNAAAA
IOAAAAA
IOAMAAA
IOBCAAA
ILAWAAA
IMNAAAA
ILAAACA
IOAAAAA
IOAMAAA
Flies
Mosquitoes
140th flies
Chigger mites
Fleas
Ticks
(Flies)
(Mosquitoes)
0.4% spray
tlO—20 gall
Al
(1 lb/gal EC)
(25% Ec)
I SASAAA
IQAUACA
IVAAABA
IOAAAAA
IOAAAFA
IOAMAAA
IOBCAAA
Ants
Boxelder bug
Cockroaches
Flies
Gnats
Mosquitoes
Moth flies
or
156
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE).
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Commercial Establishments (continued)
0.32 spray May be formulated with methyl car—
in odorless bitol(diethylene glycol monomethyl
kerosene ether).
(20% SC/L)
ISASAAA Ants 0.4% spray Indoor residual treatment. Apply
IVAAABA Cockroaches (1.63 lb/gal as a coarse wetting spray into
IMPBACA Silverfish SC/L) cracks and crevices contacting as
IKAAAAA Spiders many insects as possible. Repeat
as needed.
IOAAAAA Flies 0.1% spray Indoor space spray treatment. Apply
IOAAAFA Gnats (1.63 lb/gal with a conventional mist Bprayer.
IOAMAAA Mosquitoes SC/L) Prior to spraying extinguish all
open flames and close up area.
Leave area closed for 10 minutes.
Ventilate prior to reentry.
( Domestic and Human Use )
/860010A Human Bedding, Blankets, Mattresses
/860030A Human Clothing
IQAFACA Bed bug 1% spray Apply lightly but thoroughly to
(20% EC) beds, mattresses, and other hiding
(1.63 lb/gal places about the room. Direct the
SC/L) spray into all cracks and crevices
and around baseboards, walls, and
floors.
ITBSABA Clothes moths 0.1% spray Moth proofing treatment. Apply
(1.63 lb/gal. lightly but thoroughly to infested
SC/L) areas on clothing and bedding. Pay
special attention to folds and
seams. Repeat at 30 day intervals
as needed.
0.5% spray Moth proofing treatment. Apply to
(20% EC) materials immediately being prepared
(1.63 lb/gal for storage. Dry clean before using
SC/L) articles.
Issued: 6—05—84 iit—009001—l 13
157
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s )
/860020A Humans
Do not apply more than 0.02 ounce
per person. Allow 7 days between
applications. If possible, indivi-
duals should bathe before treatment.
Do not apply to individuals who have
insect repellents, oil, or grease
on the skin. Use a respirator or
face mask if dispensed into air with
a dust gun or blower. Allow 1 hour
for the dust to settle before reen-
tering. Do not bathe within 24
hours following treatment. Use
limited to military personnel.
IMBEABA Body louse approximately Human treatment. Remove clothing,
0.1 oz/per— turn inside out, and dust lightly
son over entire surface, rubbing the
(U D) dust well into all seams. Repeat
at 7 day intervals. To dust persons
without removing clothing, fill the
duster 75 percent full and adjust
to deliver a heavy cloud of dust at
each stroke. 1) Dust the inside of
hat and replace on head. 2) Extend
arms at side, shoulders height.
Insert the delivery tube slowly up
each sleeve between skin and inner
garment. Blow powder into arm pit
and about the shoulder. Also treat
between individual layers of cloth-
ing. 3) Insert tube at back of neck
dusting back and neckband. 4) In—
sert tube in front at neck and dust
toward armpits, both sides of body,
chest, and abdomen. 5) Loosen
trousers, insert tube between skin
and innermost garments, and powder
generously crotch and pubic area,
also underdrawers, especially waist
and side seams. 6) Insert tube down
rear of trousers next to skin and
powder buttocks and rear of crotch.
7) Dust in socks.
IMBEACA Crab louse dust Human treatment. Dust into infested
IMBEADA Head louse (1% n) hairy portions of body and work down
to the base of hair with finger
tips. Make 2 additional applica-
tions at 7 day intervals.
Issued: 6—05—84 [ II—00900 1 114
158
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Site and Pest Dosages and Tolerance, Use, Limitations
Formulation(s)
Humans (continued)
IMNAAAA Fleas dust Human treatment. Dust entire inner
(1% D) surfaces of undergarments, especial-
ly seams; also inner seams of
trousers and shirt. Rub treated
areas lightly by hand to spread dust
evenly. Repeat at 7 day intervals
and following each change of cloth-
ing.
AERIAL, MOTHPROOFING AND TANK MIX APPLICATIONS
9000900 Mothproof ing
AAAAAAA
Refer to
INDOOR
( Household )
Domestic Dwellings, Contents
( Domestic and Human Use )
Human Bedding, Blankets, Mattresses;
Human Clothing
9900300 Tank Mix
AAAAAAA
Refer to
TERRESTRIAL FOOD CROP
( Agricultural Crops )
Alfalfa, Barley, Beans, Beans (Suc-
culent), Beets, Broccoli, Brussels
Sprouts, Cabbage, Carrots, Cauli-
flower, Clover, Corn, Cotton, Cucum-
ber, Flax, Lentils, Lettuce, Melons
(including Cantaloupe and Water-
melon), Oats, Okra, Onion, Peas,
Pumpkin, Radish, Rye, Safflower,
Sorghum, Soybeans, Spinach, Squash,
Sudangrass, Sugar Beets, Sunflower,
Tomato, Wheat
INDOOR
( Wood or Wood Structure Protection Treatments )
Unseasoned Forest Products
Issued: 6—05—84 111—009001—115
159
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Listing of Registered Pesticide Products by Formulation
6099.0001 99% technical chemical
lindane (gamma isomer of benzene hexachioride) (009001)
000655—00028 000655-00393 006305—00001 007501—00101
6099.5001 99.5% technical chemical
lindane (gamma isomer of benzene hexachioride) (009001)
000359—00686 000359—00687 000359—00710 000359—00712
000550—00110 005602—00096 019713—00061 021137—00003
040083—00001
6099.9901 100% technical chemical
lindane (gamma isomer of benzene hexachloride) (009001)
019713—00191 047916—00045 049911-00001 Q52693—00fl06
6210.0002 10% formulation intermediate
lindane (gamma isomer of benzene hexachloride) (009001) plus xylene
range aromatic solvent (086803)
000655—00044 000655—00045
6220.0002 20% formulation intermediate
lindane (gamma isomer of benzene hexachloride) (009001) plus aromatic
petroleum derivative solvent (006501)
000655—00039
lindane (gamma isomer of benzene hexachioride) (009001) plus xylene
range aromatic solvent (086803)
000655—00022
6025.0002 25% formulation intermediate
lindane (gamma isomer of benzene hexachloride) (009001)
000655—00021 000655—00023
&095.0002 95% formulation intermediate
lindane (gamma isomer of benzene hexachloride) (009001)
047916—00046 O0O655—r rY c5
&000.5003 0.5% dust
lindane (gamma isomer of benzene hexachloride) (009001) plus captan
(081301)
008590—00213
lindane (gamma isomer of benzene hexachloride) (009001), methoxychlor,
technical (034001) plus sulfur or sulphur (077501)
000602—00007
&000.7503 0.75% dust
lindane (gamma isomer of benzene hexachloride) (009001)
003743—00287
Issued: 6—05—84 111—009001—116
160
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE IIEXACHLORIDEY
Listing of Registered Pesticide Products by Formulation (continued)
&001.0003 1% dust
lindane (gamma isomer of benzene hexachioride) (009001)
000226—00040 000400—00326 000769—00168 002169—00060
002217—00179 006830—00018 006830—00037 008590—00087
lindane (gamma isomer of benzene hexachloride) (009001) plus inaneb
(014505)
000226—00135
lindane (gamma isomer of benzene hexachloride) (009001) plus sulfur or
sulphur (077501)
000602—00288
lindane (gamma isomer of benzene hexachloride) (009001), zineb (014506)
plus thiram (079801)
000407—00295 000471—00009
lindane (gamma isomer of benzene hexachloride) (009001), zineb (014506),
carbaryl (056801) plus sulfur or sulphur (077501)
001386—00323
lindane (gamma isomer of bertzene hexachlot-jde) (009001), 1,1—bis(chloro—
phenyl)—2,2,2—trichloroethanol. (010501) zineb (014506), methoxychlor,
technical (034001) plus 2,4—dinitro—6 octyl*pheny1 crotonate 2,6—dini—
tro—4 —octyl*phenyl crotonate nitrooctyiphenols (principally dinitro)
*a mixture of 1—methylheptyl, l—ethylhexyl and 1 propylpentyl (036001)
000746—00110
lindane (gamma isomer of beazene hexachlorjde) (009001), 1,1—bis(chloro—
phenyl)—2,2,2—trichloroethanol (010501), zineb (014506), 2,4dinitro6
octyl*phenyl crotonate 2,6—dinitro 4_octy1*pheny1 crotonate nitrooctyl-
phenols (principally dinitro) *a mixture of 1—methyiheptyl, 1—ethyl—
hexyl and 1 propylpentyl (036001) plus carbaryl (056801)
000769—00299
&012.5003 12.5% dust
lindane (gamma isomer of benzene hexachloride) (009001) plus captan
(081301)
000655—00623
&016.6003 16.6% dust
lindane (gamma isomer of benzene hexachloride) (009001) plus 0,0—diethyl
0—(2—iaopropyl—6—methyl—4—pyrimidinyl) phosphorothiate (057801)
040831—00088
lindane (gamma isomer of benzene hexachioride) (009001), 0,0—diethyl
O—(2—isopropyl—6—methyl—4—pyrimidinyl) phosphorothiate (057801) plus
captan (081301)
008203—00002 034 704—00038 043 789—0004 1
Issued: 6—05—84 111—009001—117
161
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER 0F BENZENE HEXACHLORIDE)
Listing of Registered Pesticide Products by Formulation (continued)
&018.7503 l8.75 /. dust
lindane (gamma isomer of benzene hexachloride) (009001) plus inaneb
(014505)
000554—00109 007501—00035 008203—00008 010912—00002
019382—00006 034 704—00039 034 704—00046 043789—00019
lindane (gamma isomer of benzene hexachloride) (009001), inaneb (014505)
plus carboxin (090201)
007 50 1—00037
&025.0003 25% dust
lIndane (gamma isomer of benzene hexachioride) (009001) plus captan
(081301)
000228—00090 007501—00038 043 789—00011 043 789—00020
lindane (gamma isomer of benzene hexachioride) (009001), 0,0—diethyl
0—(2—isopropyl—6—methyl—4—pyrimidinyl) phosphorothiate (057801) plus
captan (081301)
008203—00028
&075.0003 75% dvst
l.indane (gamma isomer of benzene hexachloride) (009001) plus captan
(081301)
008203—00001
&003.0006 3% wettable powder
lindane (gamma isomer of benzene hexachioride) (009001), zineb (014506),
carbaryl (056801) plus sulfur or sulphur (077501)
001386—00073
&006.0006 6% wettable powder
lindane (gamma isomer of benzene hexachioride) (009001)
000239—01769 000299—00149 000769—00050 001157—00009
&009.0006 9% wettable powder
lindane (gamma isomer of benzene hexachioride) (009001), zinc ion and
manganese ethylene bisdithiocarbainate 80%, a coordination product of
manganese 16%, zinc 2%, ethylene bisdithiocarbamate 62% (014504),
2,4_dinitro_6_octyl*phenyl crotonate 2,6_dinitro_4_octyl*phenyl croton—
ate nitrooctyiphenols (principally dinitro) *a mixture of 1—methyl—
heptyl, 1—ethylhexyl and 1 propylpentyl (036001) plus carbaryl (056801)
a0 0602—o0 155
&0l0.0006 10% wettable powder
lindane (gamma isomer of benzene hexachioride) (009001)
003743—00339
&025.0006 25% wettable powder
lindane (gamma isomer of benzene hexachloride) (009001)
000226—00074 000239—02519 000655—00580 000746—00087
000769—00155 000904—00307 001386—00054 002393—00305
Issued: 6—05—84 111—009001—118
162
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HFIXACHLORIDE).
Listing of Registered Pesticide Products by Formulation (continued)
25% wettable powder (continued)
034704—00174 034704—00219 040831—00081 043789—00015
043 789—000 38
&075.0006 75% wettable powder
lindane (gamma isomer of benzene hexachloride) (009001)
000802—00081 034704—00220 043789—00040
&000.5007 0.5% wettable powder/dust
lindane (gamma isomer of benzene hexachloride) (009001), aromatic petro—
leum derivative solvent (006501), l,l—bis(chlorophenyl)—2,2,2—tri—
chloroethanol (010501), carbaryl (056801) plus folpet (081601)
000004—00103
6001.0007 1% wettable powder/dust
lindane (gamma isomer of benzene hexachloride) (009001)
000407—00406 002393—00361
lindane (gamma isomer of benzene hexachioride) (009001), basic copper
sulfate (008101), zineb (014506), carbaryl (056801) plus sulfur or sul-
phur (077501)
000728—00086
lindane (gamma isomer of benzene hexachioride) (009001), 1,1—bis(chloro—
phenyl)—2,2,2—trichloroethanol (010501), zineb (014506) plus 2,4—dini—
tro—6—octyl*phenyl crotonate 2,6 —dinitro—4—octyl*phenyl crotonate
nitrooctyiphenols (principally dinitro) *a mixture of 1—inethylheptyl,
1—ethyihexyl and 1 propylpentyl (036001)
002169—00114
lindane (gamma isomer of benzene hexachloride) (009001), zineb (014506),
methoxychior, technical (034001) plus 2,4—dinitro—6 —octyl*phenyl cr0—
tonate 2,6—dinitro..4 —octyl*phenyl crotonate nitrooctylphenols (pririci—
pally dinitro) *a mixture of 1—methyiheptyl, 1—ethyihexyl and 1 propyl—
pentyl (036001)
000226—00196
6025.0007 25% wettable powder/dust
lindane (gamma isomer of benzene hexachioride) (009001)
000004—00076 000239—02519 000655—00580 000802—000 76
002169—00113 040831—00097
6075.0007 75% wettable powder/dust
lindane (gamma isomer of benzene hexachloride) (009001)
000239—00353
6000.2710 0.27% impregnated materials
lindane (gamma isomer of benzene hexachioride) (009001)
003912—00001 003941—00028 007620—00001
Issued: 6—05—84 111—009001—119
163
-------
EPA Index to Pesticide Chemicals
LINDANE (CANMA ISOMER OF BENZENE REXACHLORIDE)
Listing of Registered Pesticide Products by Formulation (continued)
&002.3010 2.3% impre nated materials
lindane (gamma isomer of benzene hexachioride) (009001)
00 132 7—000 16
&005.6010 5.6% impregnated materials
lindane (gamma isomer of benzene hexachloride) (009001)
00 132 7—00015
&0ll.2O10 11.2% impregnated materials
lindane (gamma isomer of benzene hexachioride) (009001)
001327—00027 001327—00028
&lOO.3512 0.35 lb/gal emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001), aliphatic
petroleum hydrocarbons (063503) plus xylene range aromatic solvent
(086803)
00 1990—00355
&l0O.36 12 0.36 lb/gal emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001) plus xylene
(086802)
002169—00127
&101.0012 1 lb/gal emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001)
000550—00113
lindane (gamma isomer of benzene hexachloride) (009001) plus aromatic
petroleum derivative solvent (006501)
000769—00209 006830—00002
lindane (gamma isomer of benzene hexachloride) (009001) plus penta—
chloronitrobenzene (056502)
007501—00078
lindane (gamma isomer of benzene hexachloride) (009001) pluS petro-
leum distillate (063503)
006651—00011
lindane (gamma isomer of benzene hexachloride) (009001) plus xylene
(086802)
000148—00967 000400—00378 001386—00045
lindane (gamma isomer of benzene hexachloride) (009001) plus xylene
range aromatic solvent (086803)
000550—00105 000655—00747 003743—00109 006 720—00161
&l01.60l2 1.6 lb/gal emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001) plus petro-
leum distillate (063503)
003743—00302
Issued: 6—05—84 1 1 1—009001—120
164
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACIILORIDE)
Listing of Registered Pesticide Products by Formulation (continued)
1.6 lb/gal emulsifiable concentrate (continued)
lindane (gamma isomer of benzene hexach].oride) (009001) plus xylene
(086802)
004887—00155 007273—00096
lindane (gamma isomer of benzene hexachioride) (009001) pIus xylene
range aromatic solvent (086803)
000279—00868
&1O1.63l2 1.63 lb/gal emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001) plus xylene
range aromatic solvent (086803)
000655—00579 000655—00613 000655—00677
&lOl.63l2 1.63 lb/gal emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001) plus aromatic
petroleum derivative solvent (006501)
000239—02363 000769—00159 000769—00550
lindane (gamma isomer of benzene hexachioride) (009001) plus xylene
range aromatic solvent (086803)
000 728—00070
&l01.6612 166 lb/gal emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001), diisobutyl
ketone [ 2,6—dimethyl—4—heptanonej (044107) plus xylene (086802)
005602—00 120
&lOl.7012 1.7 lb/gal emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001) plus aromatic
petroleum derivative solvent (006501)
000239—02518
lindane (gamma isomer of benzene hexachioride) (009001) plus xylene
range aromatic solvent (086803)
002935—00377 008590—00384
&10l.7512 1.75 lb/gal emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001)
000802—00186
&200.4512 0.45% emulsifiable concentrate
lindane (janima isomer of benzene hexachioride) (009001), petroleum dis-
tillate (063503) plus xylene (086802)
047000—00016
&200.5012 0.5% emulsifiable concentrate
lindane (gamma isomer of beuzene hexachloride) (009001), orthodicbloro-
benzene (059401) plus petroleum distillate (063503)
005490—00001
Issued: 6—05—84 111—009001—121
165
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OFBENZENE HEXACHLORIDE)
Listing of Registered Pesticide Products by Formulation (continued)
&201.0012 1% emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001) plus kerosene
(063501)
001452-00002
lindane (gamma isomer of benzene hexachioride) (009001), heavy aromatic
naphtha (006602), petroleum distillate (063503), toxaphene (080501)
plus xylene (086802)
000070—00086
&201.6812 1.68% emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001), 2,2—dichioro—
vinyl dimethyl phosphate plus related compounds (084001) plus xylene
(086802)
001260—00076
6201.9612 1.96% emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001), petroleum die—
tillate (063503), toxaphene (080501) plus xylene (086802)
047000—00025
&202.0012 2% emulsifiable concentrate
lindane (gamma isomer of benzene hexach].oride) (009001) plus toxaphene
(080501)
00 2 393—00400
lindane (gamma isomer of benzene hexachlorzde) (009001), malathion
(057701), mineral seal oil (063502) plus xylene (086802)
000059—00123
6202.5012 2.5% emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001), aromatic petro-
leum derivative solvent (006501) plus toxaphene (080501)
002169—00158
lindane (gamma isomer of benzene hexachloride) (009001), aromatic petro—
leum derivative solvent (006501) plus toxaphene (080501)
044215—00009
6203.9012 3,9% emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001)
002382—00007
6204.2512 4.25% emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001), petroleum dis-
tillate (063503), pine oil (067002), piperonyl butoxide, technical
(067501), pyrethrins (069001), poly(oxyethylene) sorbitol mixed ether
ester (079007) plus xylene (086802)
003890—00002
Issued: 6—05—84 111—009001—122
166
-------
EPA Index to Pesticide Chemicals
LINDANE (CAIIMA ISOMER OF BENZENE HEXACHLORIDE)
Listing of Registered Pesticide Products by Formulation (continued)
&204.6012 4.6% emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001), aromatic petro-
leum derivative solvent (006501) plus naled (034401)
000239—01607
&205.0012 5% emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001)
000004—00220 005535—00092
lindane (gamma isomer of benzene hexachioride) (009001) plus aromatic
petroleum derivative solvent (006501)
000904—00215
lindane (gamma isomer of benzene hexachioride) (009001), aromatic petro-
leum distillate (006601) plus pine oil (067002)
000070—00067
lindane (gamma isomer of benzene hexachlorjde) (009001), aromatic petro-
leum derivative solvent (006501), 1,1—bis(chlorophenyl)—2,22—trj—
chioroethanol (010501), carbaryl (056801) plus malathion (057701)
000004—00115
lindane (gamma isomer of benzene hexachloride) (009001), l,1—bis(chloro—
phenyl)—2,2,2—trichloroethanol (010501), methoxychlor, technical
(034001), malathion (057701) plus xylene (086802)
000572—00227 005887—00044
&206.5012 6.5% emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001), aromatic petro-
leum derivative solvent (006501) plus xylene (086802)
000602—00039 000602—00309
&206.6312 6.63% emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001), tetrachloro—
phenols (063004) plus xylene (086802)
001022—00477
&208.8212 8.82% emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001) plus aromatic
petroleum distillate (006601)
002382—00004
&210.0012 10% emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001)
000070—00205 002393—00433
lindane (gamma isomer of benzene hexachioride) (009001) plus aromatic
petroleum derivative solvent (006501)
002217—00180 007401—00321
Issued: 6—05—84 111—009001—123
167
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF’ BENZENE REXACHLORIDE)
Listing of Registered Pesticide Products by Formulation (continued)
10% emulsifiable concentrate (continued)
lindane (gamma isomer of benzene hexachioride) (009001) plus xylene
(086802)
034704—00158
6210.6812 10.687. emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001) plus aromatic
petroleum distillate (006601)
000299—00184
&2l0.9412 10.947. emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001)) niethylated
naphthalenes (054002) plus xylene (086802)
005645—00003
6211.001.2 11% emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001) plus aromatic
petroleum derivative solvent (006501)
002382—00011
lindane (gamma isomer of benzene hexachloride) (009001) plus methylated
aromatic petroleum derivatives (054001)
004887—00018
6211.1412 11.14% emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001) plus xylene
range aromatic solvent (086803)
002393—003 71
&211.3412 11.34% emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001) plus petro—
leum distillate (063503)
000453—00115
6211.3712 11.37% emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001) plus xylene
(086802)
001022—00006 033560—00028
6212.2012 12.2% emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001), petroleum
distillate (006601) plus xylene (086802)
003890—00006
6212.2912 12.29% emulsifiable concentrate
lindane (gamma isomer of benzene hexachioricie) (009001) plua xylene
(086802)
015146—00004
Issued: 6—05—84 111—009001—124
168
-------
EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Listing of Registered Pesticide Products by Formulation (continued)
&212.5012 12.5% emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001) plus xylene
(086802)
002169—00296 028293—00044
lindane (gamma isomer of benzene hexachloride) (009001) plus xylene
range aromatic solvent (086803)
047000—00014
&212.8012 12.8% emulsifiable concentrate
lindane (gamma isomer of beuzene hexachioride) (009001) plus petro—
leum distillate (063503)
000829—00221
&212.8912 12.89% emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001) plus aromatic
petroleum derivative solvent (006501)
002 78 1—00003
liridane (gamma isomer of benzene hexachioride) (009001) plus xylene
(086802)
028293—00043
&217.0012 17% emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001)
000299—00173
&220.00l2 20% emulsifiable concentrate
lindane (gamma isomer of benzene hexachioride) (009001)
000004—00084
lindane (gamma isomer of benzene hexachloride) (009001) plus aromatic
petroleum derivative solvent (006501)
000239—01173
lindane (gamma isomer of benzene hexachlori.de) (009001) plus aromatic
petroleum distillate (006601)
040831—00080
lindane (gamma isomer of benzene hexachioride) (009001) plus heavy aro-
matic naphtha (006602)
000070—00163 000070—00273
lindane (gamma isomer of benzene hexachioride) (009001) plus cyclohexa
none (025902)
000904—00185
lindane (gamma isomer of benzene hexachloride) (009001) plus xylene
(086802)
000226—00068 000359—00711 002169—00110 007122—00041
Issued: 6—05—84 111—009001—125
169
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE HEXACHLORIDE)
Listing of Registered Pesticide Products by Formulation (continued)
20% emulsifiable concentrate (continued)
lindane (gamma isomer of beuzene hexachloride) (009001) plus xylene
range aromatic solvent (086803)
007401—00315
lindane (gamma isomer of benzene hexachioride) (009001), cyclohexanone
(025902) plus xylene (086802)
005887—00054
&225.00l2 25% emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001) plus aromatic
petroleum derivative solvent (006501)
006830—00022
lindane (gamma isomer of benzene hexachioride) (009001) plus petro—
leum distillate (063503)
043789—00073
lindane (gamma isomer of benzene hex.achloride) (009001) plus xylene
(086802)
043789—00014 043789—00053
&240.00l2 40% emulsifiable concentrate
lindane (gamma isomer of benzene hexachloride) (009001)
000682—00026
&200.50l4 0.5% flowable concentrate
lindane (gamma isomer of benzene hexachloride) (009001), l,lbis(chloro
phenyl)—2,2,2—trichloroethanol (010501), 2,4_dinitro_6_octyl*phenyl
crotonate 2 ,6 —dinitro 4—octyl*phenyl crotonate nitrooctyiphenols (prin-
cipally dinitro) *a mixture of 1—niethyiheptyl, 1—ethyihexyl and 1 pro—
pylpentyl (036001), carbaryl (056801) plus captan (081301)
000004—00125
&20l.00l4 1% flowable concentrate
lindane (gamma isomer of benzene hexachloride) (009001)
000059—00191
&230.0014 30% flowable concentrate
lindane (gamma isomer of benzene hexachloride) (009001)
007501—00034 043789—00052
&240.00l4 40% flowable concentrate
lindane (gamma isomer of benzene hexachioride) (009001)
007501—00016 043789—00051
&lol.65l5 1.65 lb/gal soluble concentrate/liquid
lindane (gamma isomer of benzene hexacbloride) (009001) plus xylene
range aromatic solvent (086803)
000550—001 12
Issued: 6—05—84 111—009001—126
170
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EPA Index to Pesticide Chemicals
LINDANE (GA lMA ISOMER OF- BENZENE HEXACRLORIDE)
Listing of Registered Pesticide Products by Formulation (continued)
&220.00l5 20% soluble concentrate/liquid
lindane (gamma isomer of benzene hexachioride) (009001), 2(2butoxy—
ethoxy)ethanol [ diethylene glycol monobutyl etherl (042204) p1u
xylene (086802)
005602—00023
&102.6716 2.67 lb/gal liquid—ready to use
lindane (gamma isomer of beuzene hexachloride) (009001)
007501—00076
&l04.0016 4 lb/gal liquid—ready to use
lindane (gamma isomer of benzene hexachloride) (009001)
010912—00023
&200.0516 0.05% liquid—ready to use
lindane (gamma isomer of beazene hexachioride) (009OO .), piperonyl
butoxide, technical (067501) plus pyrethrins (069001)
005645—00005
&200.0916 0.097% liquid—ready to use
lindane (gamma isomer of benzene hexachloride) (009001)
004691—00105
&200.10l6 0.1% liquid—ready to use
lindane (gamma isomer of benzene hexachloride) (009001)
003487—00018
lindane (gamma isomer of benzene hexachioride) (009001) plus benzyl
benzoate (009501)
028293—00040
lindane (gamma isomer of benzene hexachioride) (009001) plus rotenone
(071003) -
003487—00018 006175—00014
&200.2016 0.2% liquid—ready to use
lindane (gamma isomer of benzene hexachloride) (009001) plus petro—
leum distillate (063503)
001737—00007
&200.2516 0.25% liquid—ready to use
lindane (gamma isomer of benzene hexachloride) (009001) plus potassium
tetrathionate (075903)
000059—00192
&200.30l6 0.3% liquid—ready to use
lindane (gamma isomer of benzene hexach].oride) (009001)
034731—00003
Issued: 6—05—84 111—009001—127
171
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EPA Index to Pesticide Chemicals
LINDANE (GANMA ISOMER OF BENZENE HEXACIILORIDE)
Listing of Registered Pesticide Products by Formulation (continued)
0.3% liquid—ready to use (continued)
lindane (gamma isomer of benzene hexachioride) (009001), polyoxyethylene
lanolins (031607), sodium lauryl sulfate (079001), polyethylene glycol
distearate (079073) plus lauramide DEA (000000)
00209 7—00007
&200.5016 0.5% liquid—ready to use
lindane (gamma isomer of benzene hexachloride) (009001) pius mineral
spirits (063506)
001927—00008
lindane (gamma isomer of benzene hexachioride) (009001), methoxychlor,
technical (034001) pius mineral spirits (063506)
000495—00004
lindane (gamma isomer of benzene hexachloride) (009001), benzyl benzoate
(009501), rotenone (071003) plus xylene (086802)
0061 75—00015
lindane (gamma isomer of benzene hexachloride) (009001), aromatic petro-
leum derivative solvent (006501), methoxychior, technical (034001),
methylene chloride (042002) plus petroleum distillate (063503)
006152—00004
&20l.00l6 17. liquid—ready to use
lindane (gamma isomer of benzene hexachioride) (009001)
002169—00226 018901—00001 018901—00003
&202.0016 2% liquid—ready to use
lindane (gamma isomer of benzene hexachloride) (009001)
000395—00002 005602—00070
&203.00l6 3% liquid—ready to use
lindane (gamma isomer of benzene hexachioride) (009001)
000299—00168
&205.0016 5% liquid—ready to use
lindane (gamma isomer of benzerie hexachioride) (009001), malathion
(057701) plus petroleum distillate (063503)
006218—00015
&208.60l6 8.6% liquid—ready to use
lindane (gamma isomer of benzene hexachioride) (009001) plus maneb
(014505)
000554—00133
&210.5016 10.5% liquid—ready to use
iindane (gamma isomer of benzene hexachloride) (009001) plus maneb
(014505)
008203—00026 010912—00028
Issued; 6—05—84 1 1 100900l128
172
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF BENZENE REXACHLORIDEY
Listing of Registered Pesticide Products by Formulation (continued)
6214.6416 14.64% liquid—ready to use
lindane (gamma isomer of benzene hexachioride) (009001)
001927—00012
6225.0016 25% liquid—ready to use
lindane (gamma isomer of benzene hexachioride) (009001)
034704—00122
6200.2519. 0.25% pressurized liquid
lindane (gamma isomer of beuzene hexachioride) (009001), naled (034401)
petroleum distillate (063503)
005 185—00 196
6200.7519 0.75% pressurized liquid
lindane (gamma i8omer of benzene hexachioride) (009001)
018910—00002
6203.0019 3% pressurized liquid
lindane (gamma isomer of benzene hexachioride) (009001)
000059—00164 000299—00165 002382—00080 007056-00103
011715—00094 028293—00053 043288—00013 0442 15—00057
Issued: 6—05—84 111—009001—129
173
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EPA Index to Pesticide Chemicals
LINDANE (GAMMA ISOMER OF, BENZENE HEXACHLORIDE).
Appendix A
Listing of Common Chemical Names Used on the Entry
Chemical Common Name EPA Acceptable
Code (sourc Y Common/Chemical Name
009001 lindane lindane (gamma isomer of benzene hexachioride)
010501 dicofol l ,l—bis(chlorophenyl)—2,2,2—trichloroethanol
014504 mancozeb (Iso) zinc ion and manganese ethylene bisthiocar—
bamate 80%, a coordination product of manganese
16%, zinc 2%, ethylene bisthiocarbamate 62%
034001 methoxychior methoxychlor, technical
036001 dinocap (ISO) 2,4_dinitro—6_octyl*phenyl crotonate
2,6 —dinitro_4_octyl*phenyl crotonate
nitrooctylphenols (principally dinitro) *a
mixture of 1—methyiheptyl, 1—ethyihexyl and
1—propylpentyl
057801 diazinon (ISO) 0,0—diethyl O—(2—isopropyl—6—methyl—4—
pyrimidinyl) phosphorothioate
084001 vapona 2,2—dichlorovinyl dimethyl phosphate
Issued: 6—05—84 111—009001—130
174
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III. REQUIREMENT FOR SUBMISSION OF GENERIC DATA
A. This portion of the Guidance Document is a Notice
issued under the authority of FIFRA sec. 3(c)(2)(B). The
tables following this section list the data required for
maintaining the registrability of each product.
EPA has determined that additional generic data described
in Table A must be submitted to EPA for evaluation in order
to maintain in effect the registration(s) of your product(s)
identified as an attachment to the cover letter accompanying
this Guidance Document, As required by FIFRA Sec. 3(c)(2)(B),
you are required to take appropriate steps to comply with
this Notice.
EPA may suspend the registration of each of those products
unless, within the specified time, you have informed EPA how
you will satisfy the requirements of this Notice. Any such
Suspension will remain in effect until you have complied with
the terms of this Notice.
B. What Generic Data 1 / Must be Submitted . You may deter-
mine which generic data you must submit by consulting Table A
at the end of this chapter. That table lists the generic
data needed to evaluate the continued registrability of all
products, and the dates by which the data must be submitted.
The required studies must be conducted in accordance with
EPA approved protocols (such as those contained in the Pesticide
Assessment Guidelines 2/ or data collected under the approved
protocols of the Organization for Economic Cooperation and
Development (OECD). If you do not wish to develop data
in support of certain uses appearing in your labeling, you
may delete those uses at the time you submit your revised
labeling.
For certain kinds of testing (generally ecological
effects), EPA requires the test substance to be a “typical
formulation,” and in those cases EPA needs data of that type
1/ Generic data pertain to the properties or effects of a
particular ingredient, and thus are relevant to an evaluation of
the risks of all products containing that ingredient, regardless
of the product’s unique composition or specific use. Product—
specific data relate only to the properties or effects of a
product with a particular composition (or a group of products
with closely similar composition).
2/ The Pesticide Assessment Guidelines are available in
hard copy or microfiche from the National Technical Information
Service, 5285 Port Royal Road, Springfield, Virginia 22161.
175
-------
for each major formulation category (e.g., emulsifiable concen-
trates, wettable powders, granulars, etc.) These are classified
as generic data and when needed are specified in Table A.
EPA may possess data on certain “typical formulations” but not
on others. Note : “Typical formulation” data should not be
confused with product—specific data (Table B) which are
required on each formulation. Product—specific data are
further explained in Section IV of this document.
C. Options Available for Complying With Requirements
to Submit Data
Within 90 days of your receipt of this Notice you must
submit to EPA a completed copy of the form entitled “FIFRA
Section 3(c)(2)(B) Summary Sheet” [ EPA Form 8580—1, Appendix
11—3] for each of your products. On that form you must state
which of the following methods you will use to comply with
the requirements of this Notice:
1. (a) Notify EPA that you will submit the data, and
(b) either submit the existing data you believe will
satisfy the requirement, or state that you will generate
the data by conducting testing. If the test procedures
you will use deviate from (or are not specified in) the
Pesticide Assessment Guidelines or protocols contained in
the Reports of Expert Groups to the Chemicals Group,
Organization for Economic Cooperation and Development
(OECD) Chemicals Testing Programme, you must enclose the
protocols you will use.
OR
2. Notify EPA that you have entered into an agreement
with one or more other registrants to jointly develop (or
share in the cost of developing) the data. It you elect
this option, you must notify EPA which registrant(s) are
parties to the agreement.
OR
3. File with EPA a completed “Certification of Attempt to
Enter Into an Agreement With Other Registrants for Develop—
ment of Data” (EPA Form 8580—6, Appendix II_4)*/
/ FIFRA sec. 3(c)(2)(B) authorizes joint development of
data by two or more registrants, and provides a mechanism by
which parties can obtain an arbitrator’s decision if they agree
to jointly develop data but fail to agree on all the terms of
the agreement. The statute does not compel any registrant to
agree to develop data jointly.
(Footnote continued on next page)
176
-------
OR
4. Request that EPA amend your registration by deleting
the uses for which the data are needed. (This option is
not available to applicants for new products.)
OR
5. Request voluntary cancellation of the registration(s)
of your products for which the data are needed. (This
option is not available to applicants for new products.)
D. Procedures for Requesting Changes in Testing Methodology
and Extensions of Time
EPA recognizes that you may disagree with our conclusions
regarding the appropriate ways to develop the required data or
how quickly the data must be submitted. If the test procedures
you plan to use deviate from (or are not specified in) the
registration guidelines or protocols contained in the reports
of the Expert Groups to the Chemical Groups, Organization for
Economic Cooperation and Development (OECD) Chemicals Testing
Programme, you must submit the protocol to the Product Manager,
Registration Division, and to the Office of Compliance Monitoring
(addresses on page 252 of this Standard) for Agency review
prior to the initiation of the test.
If you think that you will need more time to generate the
required data than is allowed by EPA’S schedule, you may submit
a request for an extension of time. The extension request must
be submitted in writing to the Product Manager, Registration Divi-
sion, and to the Office of Compliance Monitoring. The extension
request should state the reasons why you believe that an extension
is appropriate. While EPA considers your request, you must strive
to meet the deadline for submitting the required data.
(Footnote continued from previous page)
In EPA’s opinion, joint data development by all registrants
subject to a data requirement or a cost—sharing agreement among
all such registrants is clearly in the public interest. Duplica-
tion of testing could increase costs, tie up testing facilities,
and subject an unnecessarily large number of animals to testing.
As noted earlier, EPA has discretion to suspend the
registration of a product when a registrant fails to submit data
required under FIFRA Section 3(c)(2)(B). EPA has concluded that
it should encourage joint testing rather than duplicative testing,
and that suspension should be withheld in certain cases.
Accordingly, it (1) a registrant has informed us of his intent to
develop and submit data required by this Notice; and (2) a second
registrant informs EPA that it has made a bona fide offer to the
first registrant to share in the expenses of the testing
[ on terms to be agreed upon or determined by arbitration under
FIFRA Section 3(c)(2)(B)(iii)J; and (3) the first registrant has
declined to agree to enter into a cost—sharing agreement, EPA
will not suspend the second firm’s registration.
177
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G 2IERIC 1 TA
TABLE A
R UIRE IFNI’S DR LINIWJE
Within
Lide1ine Citation and
1 st
Guidelines
Are Data
FoottX)te
SU Xflitted
Time Franes Listed
Nane
of
1 st
Substance
status
i quired?
Yes NO
Nunber
BelOw
1/
S158 .120 Product Ch nistry
Product Identity:
61-1 — product Identity and Disclosure
of Ingredients
61-2 — Description of Beginning
Meterials and Mara.ifacturing
Process
61-3 - Discussion of Fbrmation of
Unintentional Ingredients
Analysis and Certification of Product
Ingredients
62—1 — Preliminary Analysis
62-2 - Certification of Limits
62-3 - Analytical Metlxds to Writy
Certified Limit
rliysical and thanical tharacteristics
63—2 — O. ilor
63—3 — i*iysical State
63—4 — Cxior
63—5 — Melting Boint
63—6 — Boiling R int
TGAI
R
‘= i
IX]
1 I
R
I
L i i
6
nths
1 AI
R
LX]
[ =1
2
6
? nths
TGAI
R
[ i
0
3
12
? nths
1T AI
R
[ ]
0
12
nths
1 I
R
i=i
TGAI
R
[ =1
[ ]
L I
R
C]
[ ]
• I I
R
[ =1
[ ]
178
-------
TABLE A
74ERIC 1 TA RD uIREz4FNrS FOR LINIW4E
Guideline Citation and
Nar of 1 st
1 st
Substance
Guidelines
Status
Are Data
I quired?
Yes No
Footnote
Nunber
sthnitted Within
Tine Fr ies Listed
Below 1/
S158.120 Product th nistry (O,ntinued)
W ySiCa1 and ( anical tharacteristics
(Continued)
63-7 - Density, Bulk Density, or
Specific Gravity
TG ½I
R
[ X]
63-8 — sohbi].ity
i I
R
[ ] [ ]
63-9 - vapor pressure
1 A I
R
LX ]
63—10 — Dissociation constant
TGAI
NA
] LX]
63-11 — Octanol/water partition
coefficient
1 AI
R
[ ] 1]
6 tt)nths
63-12-pH
TGAI
NA
L i [ X]
63—13 — Stability
TGAI
R
[ 1 [ X l
Other Bequir nents:
64— 1 — Sitinitt al of sauples
i i
CR
[ 1 C)
TGAI = Technical (raie of the Petive’ Ir jredient; R = Required; CR = Conditionally Required; NA = Not Applicable
1/ Data must be sthuitted within the indicated time tr ne, based on the date ot the Guidance Ixcunent.
2/ The discussion must specifically aidress the potential for formation of d iox ins and dibenzofurans
3/ Analysis must identity and quantify all ca onents present at greater than 0.1%.
179
-------
TABLE A
GENERIC REOUIREMENTS IDR LINDANE
tX)es EPA
MUSt dditiona1
Have Data
Data Be
Time Frame
Data
Requirai nt
1/
Ccinposition
1t Satisfy
This
Requiranent?
Bibliographic
Citation
S
Sulinitted
Under FIFR1
3(c)(2)(B)
?
br Data 2/
SUkthSSiOfl
S158.125 Residue chanistry
171—4 — Nature of Residue
— plants PPJR Partially 00025707 Yes 3 ! 24 MonthS
00060143
00060150
00105413
GS O 315001
GS0315002
GS0315003
— Livestock PAIRA and Partially GS0315004 Yes 4 ! 18 Months
Plant Metabolites ( 03l5005
GS0315006
171—4 — Residue Analytical Metbod
— Plant and Animal Residues TGAI arid Partially 00025690 Reserved 5 !
00032233
00099909
05002348
05003005
05006312
0 50315007
180
-------
5158.125 1 sidue thanistry (Q ntinued)
TABLE A
GF 1ERIC 1Y TA R JIR lk2 ’l FUR LINI NE
Does EW
Have Data
1b Satisfy
This
Requirai nt?
171-4 - Stor e Stability E ta PAl
171-4 — MagnitLde of the 1 sidue —
1 sidue St .tiies 81 ,91,10/
— crcp c oup #1 — ot arxl TLter
getab1es 11/
o crop 1 - Beets
— Crop field trials
o crop 2 - C rrots
— Crop field trials
o Crop 3- S jar Beets
— Crop field trials
- ocess Food/Feed
o Crop 4 - Radishes
— Crop field trials
TEP
TEP
No
No
Yes’ 4/
1 served 15 /
1/
Data Requira nt Ccinpos it ion
Must iditiona1
Data Be
Tine Fraue
Bibliographic
Citation
S
Suh i tted
Under FIFRA
3(c)(2)(B)
?
For Data 2/
Sutinission
Metabol ites
No - Yes 6 !
No - 1 served 7 /
No — Yes 1 2/
No Yes 13 ’
TEP
12 Nonths
48 t&nths
48 Nonths
48 Nonths
48 tbnths
TEP
No
Yesl 6/
181
-------
o crop 2 - Sugar Beet ltps
— Crop field trials
o Crop 3 - Radish ltçs
— Crop field trials
- Crop Grc ip *3 - lb Vegetables
raip’O/
o Crop 1 - ions (dry bulb)
— Crop field trials
TABLE A
GF ERIC [ TA RI UIRE 1EMS FOR LINtA NE
DDes EPA
Have Data
Th Satisfy
This
Requiranent?
1/
Data Requira nt Ccinposition
f4ist i iditional
Data Be
Time I ne
Bibliographic
Citation
S
Sutinitted
der FIFRA
3(c)(2)(B)
?
F r Data 2/
Sulinission
S158.125 Residue Chanistry (Cbntinued)
171—4 - Magnitude of the Residue -
Residue Studies 8/,9/,1O/ ( ntinued)
- Crop ( c .ip *2 - I aves of ot ar Tuber
\ getable Grcxip 11 /
o Crop 1 - Beet Greens
—— Crop field trials TEP
TEP No
1’EP No
TEP No
Yes ’ 7 / 48 Pbnths
Yes’ 8 ! 48 Month.s
Yes 19 ! 48 !“ jnths
yes2l/ 48 ! nths
182
-------
o crop 1 - Oelery
— Crop field trials TEP
o CrOp 2 - L ettLce
— Crop field trials TEP
o Crop 3 - Spinach
— Crop field trials TEP
o Crop 4 — Swiss thard
— Crop field trials
TABLE A
G ERIC I TA R JIRFZ4EN I’S )R LINIY NE
Does EPA
Have Data
Tb Satisfy
This
1 quir nent?
1/
Data Bequiraient Ccznposit ion
Be
Time Frane
1 br Data 2/
Bibliographic
Citation
S
Sulinitted
X der FIFRA
3(c)(2)(B)
?
Subnission
S158.125 Residue thanistry (Continued)
171—4 - Magnitude of the Residue —
Residue Studies 8/,9/,lO/ (Continued)
- Crop & wp *4 - Leafy Wgetables
(except Brass ica)
Group 22 /
No
No
ND
No
yes2 3 / 48 Months
Yes 2 4/ 48 Months
yes25/ 48 Months
yes2 6 / 48 Months
183
-------
o crop 2 - Brussel Spr its
— crcp field trials
o crcp 3 — Cabbage
— Crcp field trials
o crop 4 - Caul itloirer
— Crop field trials
TABLE A
GF 4ERIC I TA RFQuIR 4 F LINI NE
I es EPA
Have I th
lb Satisfy
This
1 quiranent?
1/
t ta Requir tent canposit ion
l4ist Mditional
E ta Be
Time Fr
Bibliographic
Citation
Si*initted
Under FIFRA
Fbr I ta 2/
Sutinission
§158.125 1 sidue thanistry (Continued)
171—4 — Magnitude of the I sidue —
I sidue Studies 8/,9/,10/ Continued)
- Crop ip #5 - Brassica (Cole)
Leafy qetable
Grcup27r
crop 1 — Broccoli
— Crud field trials
TEP
No
-
Yes 29 /
48
t.bnths
ltP
No
-
Yes 3 O!
48
t nths
184
-------
TABLE A
G 2’JERIC £kkTA RE t1IRE 4FN S FOR LIN11 NE
I)Des EPA
Mus
t Mditional
Have Data
Data Be
Tm Frame
1/
lb Satisfy
Bibliographic
Submitted
Fbr Data 2/
t ta
I quir ment
Canposition
This
1 quir nent?
Citation
S
Uider FIFRA
3(c)(2)(B)
?
Submission
S158.l25 1 sidue thanistry (continued)
171-4 - M nitude of the 1 sidue —
I sidue Studies 8/,9/,10/ (c xitinued)
- Crop ( ip *5 - Brassica (Cole)
Leafy W etab1e
oup 27 / (continued)
o Crop S - Collards
— Crop field trials TEP No Yes 3 2/ 48 f’bnths
oCrop6-Iale
— Crop field trials TEP No Yes 3 3/ 48 nths
o Crop 7 - Mustard eens
—- Crop field trials TEP No Yes 34 / 48 ? knths
o Crop 8 - h1rabi
— Crop field trials TEP Yes 3 5/ 48 Wnths
185
-------
oCrop 1-Beans
— Crcp field trials
o Crap 2 — Beans, Succulent
— Crop field trials
o Crop 3 — Lentils
— Crop field trials
o Crop 4 - I as (md. Cowpeas)
— Crop field trials
o Crop 5 — Soybeans
— Crop field trials
- - Processed Food/Feed
TABLE A
G ERIC DATA RI UIRE NrS R LIND NE
txes EPA
Have Data
lb Satisfy
This
Requir nent?
TEP
TEP
No
No
yes 1 /
Rese :ved 42 /
1/
Data Requirai nt Ccnçosition
Must Additional
Data Be
Time Fr ne
Bibliographic
Citation
S
Sulinitted
Tinder FIFRA
3(c)(2)(B)
?
For Data 2/
Sutxnissi ofl
§158.125 Residue Ch nistry (Continued)
171-4 - Magnitude of the Residue -
Residue Studies 8/,9/,10/ (Continued)
- Crop ( c*ip *6 - Lagu Vegetables
(Succulent or Tried)
Qx .1p & their Foliage 36 !
4
TEP No
TEP No
TEP No
TEP No
yes 37 48 ‘bnths
yes 3 8 / 48 t.bnths
yes 39 / 48 Mznths
yes 40 ! 48 t’tz)nths
48 Pbnths
186
-------
o crop 1 - D gplant
— Crop field trials
o crop 2 - Feppers
— Crop field trials
o Crop 3 - l’anatoes
— Crop field trials
— Processed F.bod/Feed
- crop ( oup *8 - Cucurbit vegetable
o Crop 1 — Cucutters
— Crop field trials
TABLE A
GENERIC L TA RE UIREN NIS EUR LIN1 NE
Does EPA
Have Data
lb Satisfy
This
I ciuirenent?
TEP
TEP
No
No
yes4 6 /
i served 7 /
1/
Data 1 quira nt caiçosit ion
!4ist Aiditional
Data Be
Tm Fra
Bibliographic
Citation
Sutinitted
1er FIFRA
Ebr Data 2/
Sutxniss ion
S
3(c)(2)(B)
?
S158.125 I sidue thanistry (Cbntinued)
171—4 — Magnibxle of the I sidue -
1 sidue Stuiies 81,91,10/ (Continued)
- Crop ( cup *7 - Fruiting getables
(except cucurbits)
( oup 43 /
TEP
TEP
No
No
1es 45 /
48 nths
48 nths
48 Lknths
48 Months
TEP
No
yes 49 !
187
-------
o Crop 3 - Pm pkins
— Crop field trials
o Crop 4 - Squash
— Crop field trials
TABLE A
G 4ERIC DA TA 1*1 (JIRF2jENrs FOR LINI NE
IXes EPA
Have Data
lb Satisfy
This
I quiranent?
yes /
Yes 5 S !
48 Months
48 Months
1/
Data 1 quir ient canposition
Must i iditional
Data Be
Time Fr ne
Bibliographic
Sutini tted
For Data 2/
Citation
S
Ixider FIFRA
3(c)(2)(B)
?
Sutiniss ion
S158.125 1 sidue O nistry (Continued)
171—4 — Magnitu e of the I sidue —
1 sidue St ies 8/,9/,10/ (Continued)
— Crop Grc*ip *8 — O. curbit Vegetable
Group 48 ! (Continued)
0 Crop 2 - P lons
— Crop field trials
TEP No
TEP No
TEP No
TEP
Yes 50 / 48 Months
yesS l/ 48 Months
yes 52 / 48 Months
- crop Group #9 - ne Fruits Group 53 !
0 Crop 1 - Apples
— Crop field trials
— Processed Fbod/Feed
188
-------
- Crop ( c ip #10 - Stone Fruits Group 57 /
o Crop 1 - Apricots
— Crop field trials
o Crop 2 - therries
— Crop field trials
o Crop 3 - Nectarines
— Crop field trials
o Crop 4 - E aches
— Crop field trials
ThBLFA
CE JERIC IWM Rk UIRk11ENrs RR LINI NE
tkes E1
Have Data
lb Satisfy
This
I qUir nent?
ltp
189
1/
I ta Requirex nt Ccm positjon
?tist k ditionaj
Data Be
Thue Fr
Bibliographic
Citation
&tznitted
[ Ixier FIFRA
Fbr Data 2/
Sttini ssion
S158.125 1 sidue nistry (Continued)
171-4 - M nitix1e of the I sidue -
Besidue Stu ies 8/,9/,10/ (Continued)
- Crop ( c*ip #9 - Fruits xip 53 /
(Continued)
OCrop 2-Pears
— crop field trials
TEP No
TEP
TEP
TEP
Yes 56 ! 48 ftxiths
Yes58/ 48 l 1bnths
Yes 59 ! 48 t’bnths
Yes 6 0/ 48 l’bnths
Yes 6 1/ 48 I’tnths
-------
1/
Data Requir tent Ccinposition
§158.125 1 sidue Ch uistry (Continued)
171—4 — Magnitude of the I sidue —
! sidue studies 8/,9/,10/ (Continued)
- Crop ( Q1p *10 - Stone Fruits Grcup 57 / (Continued)
o Crop 5 — Plums
— Crop field trials
— Processed Food/Feed
o Crop 6 — Prunes
— Crop field trials
— Processed Food/Feed
o Crop 7 — Quince
— Crop field trials
- Crop ( cxip *11 - 9i a.Il Fruits and
Berries Grcup 67 /
o Crop 1 — Q apes
— Crop field trials
— Processed Food/Feed
TABLE A
GENERIC l TA RJ (JIR ?’WN1S FOR LINIW E
IXes EPA
Have Data
Tb Satisfy
This
ReQuir nent?
Pkist
Time Fra
Data Be
For Data 2/
Bibliographic
Citation
§
Sutxnitted
tinder FIFRA
3(c)(2)(B)
?
Sthaission
TEP
TEP
No
No
No
No
TEP
TEP
ye 2/
yes6 3 /
yes64/
yes65/
48 Months
48 MonthS
48 Months
48 Months
TEP No
Yes 6 6/ 48 Months
TEP
TEP
No
No
190
yes6 8 /
Yes 6 9/
48 Months
48 Months
-------
TAI3LE A
G 4ERIC DAIA R UIR14E TS )R LIN [ W4E
1)Jes EPA Ptist Niditional
Have Data Data Be Time Fr
1/ lb Satisfy Bibliographic &itiidtted For Data 2/
Data Requiren nt Ccmpos it ion This Citation Uider FIFRA Sut*niss ion
1 quir nent? S 3(c)(2)(B) ?
S158 . 125 I sidue theinistry (Continued)
171—4 — M nitude of the Residue -
Residue studies 8/,9/,10/ (Continued)
- Crop Group *11 - nal1 Fruits ar
Berries Grcxip 67 /
o Crop 2 — Stra erries
— Crcp field trials No Yes 70 ! 48 Months
— Crop Group #12 - Tree Nuts croup 71 /
o Crop 1 — I cans
— Crop field trials TEP No Yes 72 / 48 Months
- Crop Group *13 - Cereal Grains Group 73 !
[ ir 1uding Forage,
Fodder & Straw]
o crop 1 - Barley
— Crop field trials TEP yes 7 / 48 Months
— Processed Food/Feed mp Yes 7 5/ 48 Months
191
-------
TABLE A
Des
EPA
ttis
t Additional.
Data
Requir ient
1/
Canposition
Data
lb Satisfy
This
I quiranent?
Bibliographic
Citation
Data Be
Sutinitted
Under FIFRA
Time Fra
For Data 2/
Sutinission
S158.l25 1 sidue chemistry (Continued)
171—4 — Magnitude of the 1 sidue —
1 sidue Studies 8/,9/,10/ (Continued)
- Crop Group #13 — Cereal Grains Graip 73 /
[ including Forage,
Fodder & Straw] (Continued)
o Crop 2 - Corn
— Crop field trials TEP No Yes 76 / 48 f’bnths
- — Processed Food/Feed TEP No I served 77 / 48 tbnths
oCrop3- ts
— Crop field trials TEP No Yes 78 ! 48 ‘bnths
—— Processed Food/Feed TEP No I served 79 / 48 f4nths
oCrop 4-Rye
— Crop field trials TEP No Yes 8 0/ j
- — Processed Food/Feed TEP No 1 served 8 1/ 48 f bnths
o Crop 5 - Sorghuu (m c d. Nib Sorghiin)
— Crop field trials TEP No ye s 8 Zf
-- Processed Food/Feed TEP No 1 serv’ed 83 /
192
-------
1/
Data Requir ient cauposition
S158.125 1 sidue thanistry (Continued)
171—4 — Magnitude of the 1 sidue -
1 sidue Studies 8/,9/,10/ (Continued)
- Crop Grcxlp *13 - Cereal Grains Grcxip 73 /
[ including F’Drage,
Fodder & Straw] (Continued)
o Crop 6 - btheat
— Crop field trials
— Processed Food/Feed
- Crop Grc*ip #14 - Grass Forage, ixxider
and Hay Grcu $ 6 /
o Crop 1 - Sudangrass
— — Crop field trials
- Crop Grcup #15 - Non-Grass Animal Feeds
[ Forage, Fodder, Straw,
and Hay] Grc!1p 88 /
o Crop 1 — Alfalfa
—— Crop field trials
TEP
Yes 89 !
48 Munths
48 bnths
48 knths
TABLE A
GENERIC I TA Rfl)UIRF iE S FoR LINE NE
L) es EPA
Have Data
‘lb Satisfy
This
I ciuirar nt?
Must Additional
Data Be
Time F’rane
Bibliographic
Citation
Sutinitted
Under FIFRA
FOr Data 2/
Sttznission
S
3(c)(2)(B)
?
TEP
TEP
NO
No
No
TEP
Yes 8 4/
! served 8 5/
Yes 8 7/
48 Nonths
193
-------
, 1/
Data Requir ient Cc1T position
S158.125 Residue Ch nistry (Continued)
171—4 — Magnitude of the Residue —
Residue Studies 8/,9/,1O/ (Continued)
- Crop Group #15 - Non-Grass Animal Feeds
[ Fbrage, bdder, Straw,
and Hay] roup 88 / (Continued)
o Crop 2 - Clover
— Crop field trials
— Crop Group #16 - Miscellaneous Crops
o Crop 1 - Asparagus
—— Crop field trials
o Crop 2 - Avoc ios
— Crop field trials
0 Crop 3-Cotton
— Crop field trials TEP No Yes 9 3/ 48 )flthS
-— Processed Fbod/Feed TEP No yes94/ 48 !4)nths
TABLE A
GENERIC L .T1 REOJJIREMENTS WR LINfl NE
L es EPA
Have Data
lb Satisfy
This
Requir nent?
ttist Aiditional
Bibliographic
Data Be
suimitted
Time Frarie
For Data
Citation
Under FIFRk
3(c)(2)(B)
?
Sutinission
TEP
No -
yes9 0 /
48
Nonths
TEP
No
Yes 9 1/
48
Nonths
mp
yes92/
194
-------
1/
Data Requira ent Cc*nposition
S].58.125 i sidue Ch nistry (Continued)
171—4 — Magnituie of the I sidue -
1 sidue Stuiies 81,91,10/ (Continued)
— Crop ( x*ip #16 - Miscellane(XIS Crops
(Continued)
o Crop 4 - Flax
— Crop field trials
-- Processed bod/ ed
o Crop 5 - Guavas
— Crop field trials
o Crop 6 - Marigoes
— Crop field trials
o Crop 7 - l4ishroczns
— Crop field trials
o Crop 8 - Okra
— Crop field trials
TABLE A
GENERIC 1Y iI R& (JIRE 1FNl’S L DR LINIW E
I es EPA
Have Data
lb Satisfy
This
1 quirenent?
Data Be
Tine Frane
Sutinitted
i br Data 2/
Bibliographic
Citation
S
Under FIFRA
3(c)(2)(B)
?
SutraissiOn
TEP
No
TEP
No
yes96/
t j
TEP
No
Yes 9 7/
48
nths
TEP
No
Yes 98 !
48
TEP
No
Yes 99 /
48
Months
No
195
-------
TABLE A
GENERIC DAIA R UIR 1INtS R LINI NE
I es EPA
Have Data
lb Satisfy
This
1 quiranent?
o Crop 10 - Saftlc r
— Crop field trials
—— Processed Food/Feed
o Crop 11 - Sunflo r
— Crop field trials
— Processed Food/Feed
o Crop 12 - Ibbacco
—— Crop field trials
TEP
TEP
TEP
TEP
No
No
No
No
Yes 1 03/
Yes 1 04/
YeslOS/
Yes lO 6/
48 t’bnths
48 nths
48 !“bnths
48 tbnths
1/
Data I quir nt Cauposition
Must Additional
Data Be
Time Frane
Bibliographic
Sthnitted
For Data 2/
Citation
S
Under FIFRA
3(c)(2)(B)
?
Sutinission
5158.125 1 sidue Chanistry (Continued)
171-4 — Magnitude of the I sidue —
Residue Studies 8/,9/,l0/ (Continued)
- Crop Group #16 - Miscellaneous Crops
(Continued)
o Crop 9 —
Pineapples
—
Crop
field
trials
TEP
No
YeslOl/
48
t nths
--
Processed
Food/Feed
TEP
No
yeslO2/
48
nths
TEP
Yes’° 7/
48 ?, nths
196
-------
TABLE A
GENERIC DA TA R1 UIRE iEN1S FDR LINIW E
IXes EPA
t4ist Additional
Have Data
Data Be
T1IIE Frame
1/
lb Satisfy
Bibliographic
Suixaitted
br Data 2/
Data
1 quir nt
Canposition
This
I quirernent?
Citation
S
Under FIFR
3(c)(2)(B)
?
Sulxnission
5158.125 1 sidue Chauistry (continued)
171—4 — Magnituie of the sidue —
Residue Studies 8/,9/,10/
(ODntinued)
— at (includes meat, fat, l AI and
and meat by—products) Plant Metabolites Partially 00045126 Yes 108 ! 18 Months
00088165
00089592
00101478
00118724
00118725
- Milk TGAI and
Plant Metabolites Partially 00104441 Yes 109 ! 18 Months
00025685
00075989
00088048
00118722
00118723
00118725
00118739
00098785
GS0315009
GS O 3150 10
- ultry and gs TGAI and
Plant Metabolites Yes 1 ’ 0 ! 18 Months
197
-------
S 158.125 1 sidue Ch nistry (continued)
1/ Canposition: 1X I = Technical Grade of the Active Ingredient; PAIRA = Pure Active Ingredient, Radio-labeled;
PA l = Pure Active Ingredient; TEP = Typical End-Use Product
2/ 1)ie dates refers to number of nonths following receipt of this Registration Standard.
3/ None of the available metabolian studies has provided an adequate accounting of the terminal plant residues,
which may include polar and non-polar metabolites. Metaboli studies ot radiolabeled lindane are required
for representative crops fran three crop groupings (cucurbits, leafy vegetables, and a pai or stone tree
fruit). If mataboli n data differ significantly an ng these crops, then metabolian data will be required
for a representative crop fran each crop grouping for which there is a registered tolerance.
4/ ninial metaboli u stuiys are required to identify the residues of parent lindane and all netabolites in
both a lactacting ruminant (meat and milk) and poultry (meat and eggs). The lactating ruminant study must
anploy 14 C—labeied lindane with a feeding level high enough for identification of the radioactive residues
in tissues and milk. The test animals must be dosed for at least 3 consecutive days at this level. Since
lindane may also be applied as a livestock dip, the test animals must also be dipped in 14 C—labeled lindane,
in order to reflect both ncdes of exposure. If the required plant metaboli u studies result in the identi-
fication of a metabolite that is not found in animals, then an additional ruminant metabol i n study that
involves dosing with this metabolite will be required. The poultry study must nploy 14 C-].abeled lindane
with feeding level high enough for identification of the radioactive residues in tissues and eggs. The
test animals must be dosed for at least 3 consecutive days at this level. If the required plant metabolisn
studies result in the identification of a metabolite that is not found in poultry, then an additional
poultry metaboli n study involving dosing with this metabolite will be required.
5/ Niequate methodology is available only for the analysis of parent lindane itself. If the required plant and
animal netabolian studies establish that other residues of toxicological concern are present in plant and/or
animal cati cdities, appropriate analytical methodology will have to be developed and validated.
6/ r. ta delineating the stability of lindane residues irVon representative crops f ran 3 crop groupings (cucurbits,
leafy vegetables, and a tree fruit — stone or pane) are required. Also, data describing the stability of
lindane in at least one animal camodity (tissue or milk) is required. If the required plant and animal
metaboli n studies indicate the occurrence of residues ot toxicological concern (in addition to the parent
lindane itself), storage stability on these residues will also be required.
7/ if the required plant and animal netaboli n studies indicate the occurrence of residues of toxicological con-
cern (in addition to the parent 1 indane itself), storage stability on these residues will also be required.
8/ If the required 14 C—labeled studies indicate that method sensitivity tolerances uld be adequate to cover
residues in crops for which lindane is registered only for seed treatment, i.e. only very low levels of
radioactivity are observed in the raw agricultural cam d ity, then the geographical representation require—
nent for residue data reflecting seed treatment may be waived.
9/ If residue data for crops having registered soil, seed, and foliar uses indicate that significant residues
result fran fol iar treatment, then the residue data requir nents for soil and seed treatment may be waived.
198
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S 158.125 Residue Chanistry (continued)
10/ If .the required plant metabolian studies indicate the presence of other residues besides parent lindane,
residue analyses must be performed for these other canponents (in addition to parent 1 irxiane) for each crop
identified in this Registration Standard as having outstanding residue data requir nents.
11/ A group tolerance is not appropriate at this time because adequate residue data are not available for repre-
sentative crops of this group (carrot, potato, radish, and sugar beet) and the metabolian of lindane in plants
is not adequately understood.
12/ Seed treatment is considered to be a food use, unless a radiolabeled study has shown there is no transfer ot
radioactive residues fran the seed to the edible portions of the plant. An appropriate tolerance (supported
by adequate residue data fran New York, Texas/Okl ahaM, and Wisconsin) should be proposed for residues of
lirxlane on beets arising fran the treatment of beet seed. Alternatively, a radiolabeled study showing the
degree of transfer of residues fran the seed to edible portions of the plant could be used to support the
position that beet seed treatment is a non—food use that does not require a tolerance. Reca inendations for
tank mixes of lindane with other pesticides not having established tolerances on beets (roots and greens)
must be r noved fran labeling.
13/ Seed treatment is considered to be a food use, unless a radiolabeleci study has shown there is no transfer ot
radioactive residues fran the seed to the edible portions of the plant. An appropriate tolerance (supported
by adequate residue data fran California, MichigarVWisconsin, Texas/Arizona, Washington/Oregon, and New york/
New Jersey) should be proposed for residues of lindane on carrots arising f ran the treatment ot carrot seed.
Alternatively, a radiolabeled study showing the degree of transfer of residues fran the seed to edible portions
of the plant could be used to support the position that carrot seed treatment is a non—food use that does not
require a tolerance. Reca irendations for tank mixes of lindane with other pesticides not having established
tolerances on carrots must be ra oved f ran labeling.
14/ Seed treath nt is considered to be a food use, unless a radiolabeled study has shown there is no transfer ot
radioactive residues f ran the seed to the edible portions of the plant. An appropriate tolerance (supported
by adequate residue data f ran California, Minnesota/North Dakota, Idaho, Washington, Nebraska, Wyaning, and
Michigan) should be proposed for residues of lindane on sugar beets (roots and tops) arising trait the treat—
nent of sugar beet seed. Alternatively, a radiolabeled study showing the degree of transfer of residues trait
the seed to edible portion of the plant could be used to support the position that sugar beet seec treatment
is a non—food use that does not require a tolerance. Recarinendations for tank mixes of lindane with other
pesticides not having established tolerances on sugar beets (roots and tops) must be ra ved fran labeling.
15/ A processing study showing whether concentration of lindane residues occurs in sugar, molasses, and pulp will
be required if significant levels of 1 indane residues are detected in sugar beets grown fran beet seed treated
at exaggerated application rates.
16/ Seed treatment is considered to be a food use, unless a racliolabeled study has shown there is no transfer of
radioactive residues f ran the seed to the edible portions of the plant. An appropriate tolerance (supported
by adequate residue data fran California, arid Florida) should be proposed for residues of lindane on radishes
arising fran the treatment of radish seed. Alternatively, a radiolabeled study showing the degree of transfer
of residues f ran the seed to edible portion of the plant could be used to support the position that radish
seed treatment is a non—food use that does not require a tolerance. Recamendations for tank mixes of lindane
with other pesticides not having established tolerances on radishes must be r ved fran labeling.
199
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§ 158.125 1 sidue th nistry (continued)
17/ Seed treatment is considered to be a food use, unless a radiolabeled study has sI v n there is no transfer OL
radioactive residues frcin the seed to the edible portions of the plant. Since beet tops are a food it n,
an appropriate tolerance (supported by adequate residue data fran New York, Texas/Oklahczna, and Wisconsin)
should be proposed for residues of lindane on beets arising fran the treatment of beet seed. This data must
reflect the maximuu intended use and analysis for the terminal residues of concern. Alternatively, a radio-
labeled study showing the degree of transfer of residues fran the seed to edible portion of the plant could
be used to support the position that beet seed treatment is a non-food use that does not require a tolerance.
1 cam ndations for tank mixes of lindane with other pesticides not having established tolerances on beets
(roots and greens) must be r noved fran labeling.
18/ Seed treatment is considered to be a food use, unless a radiolabeled study has sIx Qn there is no transfer of
radioactive residues f ran the seed to the edible portions of the plant. Since sugar beet tops are a feed ita’a,
an appropriate tolerance (supported by adequate residue data f ran California, Minnesota/Nerth Dakota, Idaho,
Washington, Nebraska, Wyaning, and Michigan) should be proposed for residues of lindane on sugar beets (roots
and tops) arising f ran the treatment of sugar beet seed. This data must reflect the maximun intended use and
analysis for the terminal residues of concern. Alternatively, a radiolabeled study showing the degree of trans-
fer of residues f ran the seed to edible portion of the plant could be used to support the position that beet seed
treath nt is a non—food use that does not require a tolerance. Reccmnendat ions for tank mixes of I indane with
other pesticides not having established tolerances on sugar beets (roots and tops) must be r uoved fran labeling.
19/ Seed treatment is considered to be a food use, unless a radiolabeled study has shown there is no transfer of
radioactive residues f ran the seed to the edible portions of the plant. Since radish tops are a toad itan,
an appropriate tolerance (supported by adequate residue data trcin California and Florida) should be proposed
for residues of lindane on radishes arising f ran the treatment of radish seed. This data must reflect the
maxinuin intended use and analysis for the terminal residues of concern. Alternatively, a radiolabeled study
showing the degree ot transfer of residues f ran the seed to edible portion of the plant could be used to
support the position that radish seed treatment is a non—food use that does rot require a tolerance.
1 cam ndations for tank mixes of lindane with other pesticides not having established tolerances on radishes
must be raioved fran labeling.
20/ A group tolerance is not appropriate at this tune because adequate residue data are rot available tor represen-
tative crops of this group (onion and one other catnudity besides onion) and the netaboli n of lindane in 1 .elants
is rot adequately understood.
21/ I sidue data in the form of a pesticide petition to support the current tolerance of 1.0 pj zn on onions must be
sthnitted. The data must be developed fran field trials in New York, Michigan, Oregon,’ Washington, Iaaho, and
Colorado. If onions are to be subjected to all 3 nodes of application (soil, foliar, and seed treatments), then
residue data reflecting collectively all 3 nudes of application at the maxiiuun application rates are required.
Seed treatment is considered to be a food use, unless a radiolabeled study has shown there is no transfer of
radioactive residues fran the seed to the edible portions of the plant. If it can be shown that seed treatment
results in negligible residues in the edible portions of the plant, then residue data reflecting soil and foliar
applications collectively at the maxi.mun application rates will be adequate. [ Continued on next page]
200
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S 158 . 125 Residue thanistry (continued)
21/ [ Continued fran previous page] The residue data must include results fran treatment with EC formulations,
since residues Kuld be expected to be higher fran that type of forinulat ion. A pre-harvest interval (WI)
supported by adequate residue data must appear on all labels with this crop site. If treatment is restricted
to either seed, soil, or foliar application (rather than all 3 nixles), then revised labeling will be required.
1%eamu ndaticns for tank mixes of lindane with other pesticides not having established tolerances on onions
must be raioved fran labeling.
22/ A group tolerance is not appropriate at this time because adequate residue data are not available for repre-
sentative crops of this group (celery, lettuce, and spinach) and the metabolian of lindane in plants is r t
adequately understood.
23/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 pjin on celery must be
submitted. The data must be developed fran field trials in California, Florida, Michigan, and Washington.
The residue data s1 ild reflect analyses on both trinitud and untrimned sanples, as untrinined celery may enter
interstate caiii rce. Qily obviously decanposed outer leaves or pet ioles should be retoved. since both fol jar
and soil applications are permitted, residue data reflecting collectively both modes of application at the
maximun application rates are required. Alternatively, it use is limited to either soil or foliar application,
then revised labeling shcMing only one method of application will be required. The residue data must include
results fran treatment with EC formulations, since residues are expected to be higher fran that type of
fornnilation. A definite pre—harvest interval (WI) in terms of days, supported by adequate residue data,
must appear on all lindane labels with the celery use, rather than the current vague restriction against
applying after it is half gr n or has begun to bunch. Revised labeling must be submitted that specify the
nunber of applications permitted per season and the time period bet en these applications. Recamendat ions
for tank mixes of lindane with other pesticides not having established tolerances on celery must be retoved
fran labeling.
24/ Residue data in the form of a pesticide petition to support the current tolerance of 3 • 0 ppn on lettuce must
be sutinitted. The data must be developed fran field trials in California, Florida, Texas/Arkansas, New York!
New Jersey, Colorado, and Washington. Pdequate greenhouse trials (including storage stabi1it ’ data for lindane
residues on lettuce and details of the analytical methodology) are also required to support the tixaigation use
on this crop. The residue data should reflect analyses carried out on sauples which have received the minimun
ancunt of trizwning expected or lettuce which enters interstate canneroe. Only obviously decanposed outer
leaves should be raroved. since untriiiii d lettuce may also enter interstate caimerce, untrinn d sanples
should also be analyzed. If lettuce is to be subjected to all 3 nodes of application (soil, foliar, and seed
treatments), then residue data reflecting collectively all 3 nodes of application at the maximun application
rates are required. If it can be shc ,in that seed treatment results in negligible residues in the edible por-
tions of the plant, then residue data reflecting soil and toliar applications collectively at the maximun
application rates will be adequate. The residue data must include results tran treatment with EC formulations,
since residues would be expected to be higher t ran that type of formulation. A definite pre-harvest interval
(WI), supported by adequate residue data, must appear on all labels with the lettuce use pattern rather than
the current vague instruction not to apply after the seedling stage. [ Continued on next page]
201
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S 158.125 Residue Chanistry (continued)
24/ [ Continued fran previous page] if treatment is limited to either seed, soil, or foliar application (rather
than all 3 nodes), then revised labeling will be required. Revised labeling must be sthnitted that specify
the total nuiter of appl ions permitted per season and the time period between these applications.
Recait ndatjons for tank mixes ot lindane with other pesticides not having established tolerances on lettuce
must be ra oved fran labeling.
25/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 p xn on spinach must be
submitted. The data must be developed fran field trials in California, Texas/Okiahana, New Jersey, Maryland/
Virginia, and Colorado/Arkansas. it spinach is to be subjected to all 3 nodes of application (soil, toliar,
and seed treath ents), then residue data reflecting collectively all 3 nodes of application at the maxirnun
application rates are required. If it can be shown that seed treatment results in negligible residues in the
edible portions of the plant, then residue data reflecting soil arid foliar applications collectively at the
maximun application rates will be adequate. The residue data must include results fran treatment with EC
formulations, since residues would be expected to be higher f ran that type of formulation. The curent
instruction limiting lindane application to spinach in the seedling stage is too vague. A more definite
pre-tharvest interval (Ll n), expressed in terms of days or the height of the seedling, must appear on all
labels with the spinach use pattern, If treatment is limited to either seed, soil, or toliar application
(rather than all 3 nodes), then revised labeling will be required. Revised labeling must be sutmitted that
specify the total ruinber of applications permitted per growing season arid the time period between these
applications, Recattnendations for tank mixes of lindane with other pesticides not having established
tolerances on spinach must be r ioved trati labeling.
26/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 ppn on Swiss chard
must be sufruitted. The data must be developed f ran field trials in California, New Jersey, and Texas.
Appropriate labeling describing the application methods and rates, and any limitations, pertaining to the
use of liridane on swiss chard must also be sutmitted.
27/ A group tolerance is not appropriate at this time because adequate residue data are not available tor repre—
sentat ive crops ot this group (broccoli, cabbage, and mustard greens) and the metabol i n of 1 indane in
plants is not adequately understood.
28/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 ppn on broccoli must
be si.friitted, The data must be developed trcin tielci trials in California, Texas/Arizona, arid Oregon. If
broccoli is to be subjected to all 3 nodes of application (soil, toliar, and seed treatments), then residue
data reflecting collectively all 3 nodes of application at the maximun application rates are required. If
it can be shown that seed treatment results in negligible residues in the edible portions of the plant, then
residue data reflecting soil and foliar applications collectively at the maximun application rates will be
adequate. The residue data must include results f ran treatment with EC formulations, since residues would
be expected to be higher f ran that type of formulation. Revised labeling ‘mist be sutmitted showing a pre-
harvest interval (r iI), in terms of days, associated with the use of lindane applied to the soil around the
base of the plant. Also, revised labeling must be sutmitted that specifies the total number of applications
permitted per growing season for either the toliar or the soil (plant base) application method and the time
period between these applications. it treatment is limited to either seed, soil, or toliar application
(rather than all 3 modes), then revised labeling will be required. Recarinendations for tank mixes of lindane
with other pesticides not having established tolerances on broccoli must be removed f ran labeling.
202
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S 158.125 Residue ch nistry (continued)
29/ Residue data in the tonn of a pesticide petition to support the current tolerance of 1.0 ppn on brussels sprouts
mUst be sutinitted. The data must be developed fran field trials in California, New York, and Oregon. It
brussels sprouts are to be sibjected to all 3 nodes of application (soil, fol jar, and seed treatments), then
residue data reflecting collectively all 3 iwxles of application at the maxinuxn application rates are required.
If it can be shown that seed treath nt results in negligible residues in the edible portions of the plant, then
residue data reflecting soil and foliar applications collectively at the maxinnzn application rates will be
adequate. The residue data imist include results fran treatment with EC formulations, since residues would be
expected to be higher fran that type of formulation. Revised labeling must be sutxnitted showing a pre-harvest
interval (PHI), in terms of days, associated with the use of 1 indane applied to the soil around the base of
the plant, and specifying the total nutt er ot applications permitted per growing season for either the foliar
or the soil (plant base) application method and interval between these applications. If treatment is limited
to either seed, soil, or toliar application (rather than all 3 nodes), then revised label ing will be required.
Recam ndations for tank mixes of ]jndane with other pesticides not having established tolerances on brussels
sprouts must be r ioved tran labeling.
30/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 pJln on cabbage must be
s hnitted. The data must be developed fran field trials in California, New York/New Jersey, Florida, Texas,
Wisconsin, and South Carolina/North Carol ina/Georg ia/Tennessee. It cabbage is to be subjected to all 3 nvxles
of application (soil, toliar, arxi seed treatments), then residue data reflecting collectively all 3 nodes of
application at the maxiim.in application rates are required. If it can be shown that seed treatment results in
negligible residues in the edible portions of the plant, then residue data reflecting soil and foliar ap dica—
t ion collectively at the maximun application rates will be adequate. The residue data must include results
f ran treatment with EC formulations, since residues would be expected to be higher tran that type of formula-
tion. Revised labeling nust be siljiii tted showing a pre—harvest interval (PHI), in terms of days, associated
with the use of lindane applied to the soil around the base of the plant, and specifying the total minber of
applications permitted per growing season for either the fol jar or the soil (plant base) application method
and the time period bet en these applications. It treatit nt is l imited to either seed, soil, or toliar
application (rather than all 3 nodes), then revised labeling will be required. Recatinendations tor tank mixes
of lindane with other pesticides not having established tolerances on cabbage must be raioved fran labeling.
31/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 p in on cauliflower
must be sutinitted. The data must be developed fran field trials in Washington/Oregon, California, Florida,
Texas/ArizOna, New York, and Michigan. If caulitl r is to be subjected to all 3 nodes of application
(soil, toliar, and seed treatments), then residue data reflecting collectively all 3 nodes of application at
the inaximun application rates are required. If it can be shown that seed treatment results in negligible
residues in the edible portions of the plant, then residue data reflecting soil and toliar application collec-
tively at the maxinu.sn application rates will be adequate. The residue data must include results t ran treatment
EC fornuilations, since residues ild be expected to be higher fran that type of formulation. 1 evised labeling
must be st±initted sIuirjir a pre-harvest interval (PHI), in terms of days, associated with the use ot lindane
applied to the soil arour i the base of the plant, and specifying the total nuther ot applications permitted
per growing season for either the fol iar or the soil application method and the t l ine (Continued on next page]
203
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S 158.125 Residue Ch itistry (continued)
31/ [ Continued fran previc*is page] period bet en these applications. If treatment is limited to either seed,
soil, or foliar application (rather than all 3 ixxies), then revised labeling will be required. Reccim rx1a—
tions for tank mixes of lindane with other pesticides not having established tolerances on cauliflower must
be r ved fran labeling.
32/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 PI1U On collards must
be sthnitted. The data must be developed fran field trials in F1orida/Georgj south Carolina, Texas/Arizona,
and New Jersey. If collards are to be subjected to both soil and foliar treatment, then residue data ref lec—
ting soil and foliar treatments at the maximum application rates are required. The residue data must include
results fran treatment with EC formulations, since residues u1d be expected to be higher fran that type of
formulation. Revised labeling Dust be sut nitted showing a more definite pre—harvest interval (PHI), rather
than the current restriction against applying lindane after the edible parts of the plant have appeared (since
the edible part of the plant is the leaf, which appears as soon as the plant sprouts). In addition, revised
labeling must specify the nunber of applications permitted per growing season for the foliar application
method and the interval between these applications. Reciienciations for tank mixes of 1 indane with other
pesticides not having estab]. ished tolerances on cabbage must be removed f ran labeling.
33/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 ppn on kale must be
suixuitted. The data must be developed f ran field trials in Georgia, California, Texas, and Virginia. It kale
is to be subjected to both soil and foliar treatment, then residue data reflecting soil and foliar treatments
at the maxiitun application rates are required. The residue data must include results frau treatment with EC
formulations since residues would be expected to be higher fran that type of formulation. Revised labeling
must be sul:initted showing a more definite pre—harvest interval (PHI), rather than the current limithti
against applying lindane after the edible parts of the plant have appeared (since the edible part of the plant
is the leaf, which appears as soon as the plant sprouts). In addition, revised labeling must specify the num-
ber of applications permitted per growing season for the foliar application method and the interval between
these applications. Recamt ndations for tank mixes of lindane with other pesticides not having established
tolerances on kale must be r noved f ran labeling.
34/ Residue data in the form of a pesticide petition to support the current tolerance at 1.0 p n on mustard greens
must be sthnjttecj. The data must be developed fran field trials in Texas/Arizona, California, and Florida.
Appropriate labeling describing acceptable application methods and rates, and any limitations, pertaining
to the use of lindane on mustard greens must also be sulinitted.
35/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 p in on kohlrabi must
be sufinitted. The data must be developed fran field trials in Texas, and California. Appropriate labeling
describing acoeptable application methods and rates, and any limitations, pertaining to the use of lindane
kohirabi must also be sutmitted.
36/ A group tolerance is not appropriate at this time because adequate residue data are not available for repre-
sentative crops of this group (beans - one succulent and one dried variety; peas - one succculent and one
dried variety; and soybeans) and the metabolian of lindane in plants is not adequately understood.
204
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S 158.125 1 sidue Chanistry (continued)
37/ seed treatment is considered to be a food use, unless a radiolabeled study has shown there is no transfer of
radioactive residues fran the seed to the edible portions of the plant. An appropriate tolerance (supported
by adequate residue data fran areas where the type(s) of bean included in this use are grown) should be 1 ro-
posed for residues ot lindane on beans (i.e., the second generation or beans) arising fran the treatnent of
bean seed. Alternatively, a radiolabeled study showing the degree of transfer of residues tran the seed to
aerial portions of the plant could be used to support the position that bean seed treatn nt is a non-food
use that does not require a tolerance. Since bean forage and hay are teed it , it will also be necessary
to either sub it residue data on forage and hay grown fran treated seed or to suLinit revised labeling that
prohibits the feeding of bean hay and forage to livestock. Revised labeling must be sutxnitted that states
either the type of bean (such as garbanzo, mung, etc.), or for a nore general use, whether the beans are to
be succulent or dried. Currently, the dosage for “Beans” is 1 ounce per 100 pounds of seed, while the dosage
for succulent beans is 0.5 ounces per 100 pounds of seed. If the ca unodity “Beans” is to include succulent
beans, these disparate dosages will have to be brought into agre t nt in revised labeling. Recxmnendations
for tank mixes of 1 indane with other pesticides not having established tolerances on beans must be rauved
f ran labeling.
38/ Seed treath nt is considered to be a food use, unless a radiolabeled study has shown there is no transfer of
radioactive residues f ran the seed to the edible portions of the plant. An appropriate tolerance (supported
by adequate residue data on several types of succulent bean t ran New York/New Jersey/Delaware, Tennessee/
North Carolina/Virginia, California, Michigan, and Florida should be proposed for residues of lindane on
beans (i.e., the second generation of beans) arising fran the treatit nt of bean seed. Alternatively, a radio—
labeled study showing the degree of transfer of residues f ran the seed to aerial portions of the plant could
be used to support the position that bean seed treatir nt is a non—food use that does not require a tolerance.
Since bean forage and hay are feed it ns, it will also be necessary to either sul:ntit residue data on forage
and hay grown f ran treated seed or to sutxnit revised labeling that prohibits the feeding ot bean hay and
forage to livestock. Currently, the dosage for succulent beans is 0.5 ounces per 100 pounds of seed, while
the dosage for ‘ beans” is 1 ounce per 100 pounds of seed, It the cc1m Jdity “Beans” is to include succulent
beans, these disparate dosages will have to be brought into agre nent in revised labeling. Recarn ndations
tor tank mixes of lindane with other pesticides not having established tolerances on beans must be r veu
fran labeling.
39/ Seed treath nt is considered to be a tood use, unless a radiolabeled study has shown there is no transfer ot
radioactive residues f ran the seed to the edible portions of the plant. An appropriate tolerance (supported
by adequate residue data f ran Washington and Idaho should be proposed for residues of lindane on lentils (i.e,
the second generation of lentils) arising fran the treatn nt of lentil seed. Alternatively, a radiolabeled
study showing the degree of transfer of residues fran the seed to aerial portions of the plant could be used
to support the position that lentil seed treatn nt is a non—food use that does not require a tolerance.
Since lentil forage and hay are livestock feed it ns, it will also be necessary to either sutinit residue
data on and hay grown fran treated seed or to sutinit revised labeling that prohibits the feeding of lentil
hay and forage to livestock. RecamendatiOns for tank mixes of lindane with other pesticides not having
established tolerances on lentils must be reioved fran labeling.
205
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§ 158.125 Residue Ch nistry (continued)
40/ Seed treatment is considered to be a toad use, unless a radiolabe1ecj study has shown there is no transfer of
radioactive residues fran the seed to the edible portions of the plant. An appropriate tolerance (supported
by adequate residue data on several types of dried and succulent peas fran Illinois, Delaware, Calitornia,
Idaho, T xas and Florida should be proposed for residues of lindane on peas (i.e., the second generation
of peas) arising fran the treatment of pea seed, Alternatively, a radiolabeleci study showing the degree of
transfer of residues fran the seed to aerial portions of the plant could be used to support the position that
pea seed treatment is a non—food use that does not require a tolerance. Since pea vines and hay are livestock
teed items, it will also be necessary to either submit residue data on vines and hay grown tran treated seed
or to submit revised labeling that prohibits the feeding of pea vines and hay to livestock. Recam enc1ations
for tank mixes of lindane with other pesticides not having established tolerances on peas must be renxved
fran labeling.
41/ Seed treatment is considered to be a food use, unless a radiolabeled study has shown there is no transter of
radioactive residues fran the seed to the edible portions ot the plant. AJI appropriate tolerance (supported
by adequate residue data fran Mississippj/ uisiana Tennessee, Arkansas, Indiana/Illinois, Idaho/Nebraska,
Minnestoa, and Missouri should be proposed for residues of lindane on soybeans (i.e., the second generation
of beans) arising f ran the treatment of soybeans seeds. Alternatively, a radiolabelecj study showing the
degree of transfer of residues fran the seed to aerial portions of the plant Could be used to support the
position that soybean seed treatment is a non—food use that does not require a tolerance. Since soybean hay,
straw, and forage are livestock feed items, it will also be necessary to either submit residue data on these
items or to submit revised labeling that prohibits the feeding ot soybean hay, straw, and forage to livestock.
RecaniTendatjons for tank mixes of lindane with other pesticides not having established tolerances on soybeans
must be removed f ran labeling.
42/ If residues occur on soybeans as a result of seed treatment, a processing study involving analyses of hulls
meal, oil, and soapstock will be required. If concentration occurs in any by—product, food/feed additive
tolerances will be needed. A food additive tolerance will not be needed for residues ot lindane in refined
oil, however, because it has been shown that lindane residues do not Survive the deodorization and hydrogen-
ation processes.
43/ A group tolerance is not appropriate at this time because adequate residue data are not available tor repre-
sentative crops of this group (tanatoes and peppers) and the metabo1i n of lindane in plants is not adequately
understood,
44/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 p m on eggplants must
be submitted. The data must be developed f ran field trials in California, Florida, 1 xas, and New Jersey.
The residue data must include results fran treatment with EC formulations since residues uld be expected to
be higher fran that type of formulation. Revised labeling must be submitted that specifies the total nunber
of aWl ications permitted per growing season and the interval between these applications. Reccrrtnendations
for tank mixes of lindane with other pesticides not having estabi isheci tolerances on eggplant must be r ved
fran labeling.
206
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S 158.125 Residue Ch nistry (continued)
45/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 p xu on peppers must be
suhuitted. Data on bell peppers must be developed frau field trials in in California, Florida, Texas, North
Carolina, and New Jersey. Unless revised labeling is sulxnitted to limit the use on peppers to bell peppers
only, data on several varieties of naller peppers (such as chili peppers) must be developed fran field trials
in California and Texas/Arizona/New Mexico. Residue data reflecting both soil and toliar application at the
maximum application rates are required unless revised labeling is sutinitted that limits application only to
on of the methods. The residue data must include results frau treatment with EC foritLilations, since residues
would be expected to be higher frau that type of formulation. Revised labeling must specify the number of
applications permitted per growing season for the fol iar application method and the interval bet en these
applications. Reca u ndations for tank mixes of lindane with other pesticides not having established toler-
ances on peppers must be rQuoved f ran labeling.
46/ Residue data in the form of a pesticide petition to support the current tolerance of 3.0 p in on tanatoes must be
suhnitted. The data must be developed fran field trials in California, Florida, ohio/Pennsylvania, New Jersey,
Indiana, Michigan, and South Carolina/Tennessee. Adequate yreenhouse trials (including storage stability data
for lindane residues on tanatoes and details ot the analytical methodology) are also required to support the
fumigation use on this crop. Since higher residues may occur in cherry tanatoes, residue data on cherry
tanatces reflecting an adequate geographical representation are required. It tauatoes are to be subjected to
all 3 nodes of application (soil, fol iar, and seed treatments), then residue data reflecting collectively all
3 nodes of at the maximum appi icat ion rates are required. It it can be shown that seed treatn flt results in
negligible residues in the edible portions of the plant, then residue data retlecting soil and toliar appli-
cations collectively at the maximum application rates wil .1 be adequate. The residue data must include results
fran treatment with EC tormulations, since residues uld be expected to be higher f ran that type ot formulation
If treatment is limited to either seed, soil, or foliar application (rather than all 3 nodes), then revised
labeling will be required. Revised labeling must be sutanitted that specity the total number of applications
permitted per season and the interval bet en these applications. Recaanendat ions for tank mixes of 1 indane
with other pesticides not having established tolerances on tanatoes must be raioved tran labeling.
47/ Since tanatoes are processed into the teed ite ns, t and dry panace, and the food itans, puree and juice,
residue data on these camiodities are required in order to determine whether food and teed additive tolerances
needed.
48/ A group tolerance is not appropriate at this time because adequate residue data are not available tor repre-
sentative crops of this group (cucumbers, melons - cantaloupe or muskmelon, and s umer squash) and the
netaboli3tl of lindane in plants is not adequately understood.
49/ Residue data in the form of a pesticide petition to support the current tolerance of 3.0 pjin on cucumbers must
be sibnitted. The data must be developed fran field trials in California, Florida, Texas, Michigan, New York/
New Jersey, North Carolina/South Carolina, and Ohio. LA iequate greenhouse trials (including storage stability
data for lindane residues on cucumbers and details of the analytical methodology) are also required to support
the fumigation use on this crop. If cucumbers are to be subjected to all 3 nodes of application (soil, toliar,
and seed treati nts), then residue data reflecting collectively all 3 nodes ot [ Continued on next pagel
207
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S 158.125 Residue Ch nistry (continued)
49/ [ Continued fran previous pages application at the maximun application rates are required. It it can be
shown that seed treatment results in negligible residues in the edible port ions ot the plant, then residue
data reflecting soil and foliar applications collectively at the maximum application rates Will be adequate.
Residue data must include results fran treatment with EC formulations, since residues ild be expected to
be higher fran that type of formulation. If treath nt is limited to either seed, soil, or toliar application
(rather than all 3 nodes), then revised labeling will be required. Revised labeling must be sutinitted that
specifies the total number of applications permitted per season and the interval bet en these applications.
Current labeling stipulates a pre—harvest interval (1 II) of 1 day but also includes a limitation ajainst use
after blossans open. A pre—harvest interval, supported by residue data, must be established to eliminate
this disparity. Labeling for those products canposed of lindane in canbination with maneb must reflect the
nore stringent precautions applicable to each pesticide. A pre—harvest interval, supported by residue data,
nust be established which is ccinpatible with both pesticides. Reca u ndations for tank mixes of lindane
with other pestcides not having established tolerances on cucumbers must be r noved t ran labeling.
50/ Residue data in the form of a pesticide petition to support the current tolerance of 3.0 p xn on melons must
be sutxnitted. Data on cantaloupes must be developed fran field trials in California, Texas/Arizona, Indiana,
Michigan, and Georgia/South Carolina. Data on watermelons must be developed f ran field trials in Florida!
Georgia, Texas, and California. If melons are to be subjected to all 3 modes of application (soil, foliar,
and seed treatments), then residue data reflecting collectively all 3 nodes at the maximum application rates
are required. If it can be shown that seed treatment results in negligible residues in the edible portions
of the plant, then residue data reflecting soil and toliar applications collectively at the maximum applica-
tion rates will be adequate. Residue data nust include results f ran treatment with EC formulation, since
residue uld be expected to be higher fran that type of formulation. If treatment is limited to either
seed, soil, or foliar application (rather than all 3 nodes), then revised labeling will be required.
Revised labeling must be sutxnitted that specifies the total number of applications permitted per season and
the interval bet en these applications. Labeling for those products canposed of 1 indane in canbinat ion
with maneb must reflect the nore stringent precautions applicable to each pesticide. A pre-harvest interval
(Ff1), supported by residue data, must be established which is canpatible with both pesticides. Recami nda-
ticns for tank mixes of lindane with other pesticides rot having established tolerances on melons must be
ra oved f ran labeling.
51/ Residue data in the form of a pesticide petition to support the current tolerance of 3.0 p in on pumpkins must
be sutxnitted. Data must be developed fran field trials in California, Texas, Illinois, New Jersey, and Oregon.
If pumpkins are to be subjected to all 3 nodes of application (soil, foliar, and seed treatments), then residue
data reflecting collectively all 3 nodes at the maxinun application rates are required. If it can be shown
that seed treath nt results in negligible residues in the edible portions of the plant, then residue data
reflecting soil and foliar applications collectively at the maximum application rates will be adequate.
Residue data must include results f ran treatmt nt with EC formulation, since residue uld be expected to be
higher fran that type of formulation. If treatment is limited to either seed, soil, or toliar application
(rather than all 3 nodes), then revised labeling will be required. Revised labeling must be sulrznitted that
specifies the total number of applications permitted per season and the interval [ Continued on next page]
208
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S 158.125 1 sidue Chemistry (continued)
51/ [ Continued fran previous page] between these applications. Current labels stipulate a pre—harvest interval
(PHI) of 1 day, bet also include a 1 imitation against use after blossans open. A pre—harvest interval,
supported by residue data, must be established to eliminate this disparity. Labeling for those products
canposed of lindane in canbination with maneb must reflect the nore stringent precautions applicable to each
pesticide. A pre—harvest interval, supported by residue data, must be established which is canpatible with
both pesticides. Recatinendations for tank mixes of lindane with other pesticides rot having established tol-
erances on punpkins must be ra ved fran labeling.
52/ Residue data in the form of a pesticide petition to support the current tolerance of 3.0 ppn on squash must be
subaitted. Data on sutner squash must be developed fran field trials in California, Florida, Michigan, Texas,
Oregon, New York/New Jersey/Massachusetts, and Georgia/South Carolina. Data on at least t different kinds
of winter squash are required. The data on winter squash should be generated fran areas where these squash
are grown cati ercially. Alternatively, revised labeling can be sutxnitted in which the types of squash to be
treated with 1 indane are 1 iiuited to those for which adequate residue data have been generated. It squash are
to be subjected to all 3 nodes of application (soil, foliar, and seed treatments), then residue data retlec—
ting collectively all 3 nodes at the maximun application rates are required. If it can be shown that seed
treatment results in negligible residues in the edible portions of the plant, then residue data reflecting
soil and foliar applications collectively at the maximiin application rates will be adequate. Residue data
must include results fran treath nt with EC tormulation, since residue uld be expected to be higher t ran
that type of formulation. It treatment is limited to either seed, soil, or foliar application (rather than
all 3 nodes), then revised labeling will be required. Revised labeling must be sutmitted that specifies the
total nunber of applications permitted per season and the interval between these applications. Labeling for
those products cci, osed of lindane in canbination with maneb must reflect the nore stringent precautions
applicable to each pesticide. A pre—harvest interval (PHI), supported by residue data, must be established
which is cxinpatible with both pesticides. Current labels indicate a 1 day PHI, bet they also include a
rote that late fol jar application may result in reduction of quality at harvest • A revised PHI, supported
by adequate residue data, should be proposed that wxild eliminate the quality loss problem. Recailnendations
for tank mixes of lindane with other pesticides not having established tolerances on squash must be raioved
frau labeling.
53/ A group tolerance is not appropriate at this tine because adequate residue data are not available for repre-
sentative crops of this group (apples and pears) and the netabolimu of lindane in plants is not adequately
understood.
54/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 p n on apples must
be sukxnitted. Data on apples must be developed f ran field trials in California, Michigan, New York, Pennsyl-
vania/i st virginia, virginia/North Carolina, and shington. since apples are to be subjected to both toliar
and bark treatment, residue data reflecting toliar and bark at the maximun application rates are required.
Residue data must include results fran treatment with EC formulation, since residues w uld be expected to be
higher f ran that type of formulation. If treatment is limited to either foliar or bark treatment (rather
than both), then revised labeling will be required. The 60 day pre—harvest interval (PHI) does rot appear
to be caipatible with the prohibition against application atter first cover. [ Continued on next page]
209
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S 158.125 Residue th nistry (cx,ntinued)
54/ [ Continued frau previous page] Treatment 60 days before harvest u1d generally occur after first cover.
Revised labeling is required to resolve this discrepancy. If the 1411 is related to the growth stage (such
as first cxwer), residue data fran rapidly maturing apple varieties uld also be required. The dosage rate
for foliar application sluild be expressed in terms of pounds per 100 gallons (lbs/100 gal) and as a range
in pounds per acre (lbs/acre). The dosage in terms of lbs/acre is based on the nunber of gallons of dilute
spray needed to spray one acre of trees to the point of runoff or the equivalent anount of product per acre
in concentrate sprays. A prohibition against grazing 1 ivestock on cover crops beneath treated trees must be
added to all lindane end-use products with directions for use on apples. Revised labeling must be sutntitted
that specifies the total rut er of applications permitted per season and the interval between these applica-
tions for both the foliar treatment and the bark treatment methods of application.
55/ Residue data are required for wet and dry apple panace in order to determine whether feed additive tolerances
are needed. Residue data are required for apple juice in order to determine whether a food additive tolerance
is needed.
56/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 p iin on pears must be
si*m itted. r ta on pears nnist be developed fran field trials in California, Michigan, New York, and Washing-
ton. Since pears are to be Subjected to both foliar and bark treatment, residue data reflecting toliar and
bark at the maxirmin application rates are required. i sidue data must include results f ran treatment with
EC formulations, sir e residues wxild be expected to be higher fran that type of formulation. It treatment
is limited to either foliar or bark treatment (rather than both), then revised labeling will be required.
The dosage rate for foliar application should be expressed in terms of pounds per 100 gallons (lbs/lOO gal)
and as a range in pounds per acre (lbs/acre). The dosage in terms of lbs/acre is based on the nunber of
gallons of dilute spray needed to spray one acre of trees to the point of runoff or the equivalent a unt of
product per acre in concentrate sprays • A prohibition against grazing livestock on cover crops beneath
treated trees must be added to all 1 indane end-use products with directions for use on pears. Revised label-
ir j must be si ini tted that specifies the total nunber of applications permitted per season and the interval
between these applications for both the foliar treatment and the bark treatment methods of application.
57/ A group tolerance is not appropriate at this time because adequate residue data are not available for repre-
sentative crops of this group (sour or sweet cherries, peaches, and phins or fresh prunes) and the metabol i n
of lindane in plants is not adequately understood.
58/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 p in on apricots must
be sutinitted. 1 ta on apricots must be developed fran field trials in California, Michigan, Colorado, Arizona,
and WashingtorVOregonhldaho. The dosage rate tor bark application should be expressed in terms of pounds per
100 gallons (lbs/100 gal) and as a range in pounds per acre (lbs/acre). The dosage in teruis of lbs/acre is
based on the nwter of gallons of dilute spray needed to spray one acre of trees to the point ot runoft. A
prohibition against grazing livestock on cover crops beneath treated trees must be added to lindane end-use
products with directions for use on apricots. Revised labeling must be sthnitted that specifies the total
nuiiber of applications permitted per season and the interval between these applications for the bark treat-
ment method of application.
210
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S 158.125 1 sidue C nistry (continued)
59/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 p in on cherries must
be sitinitted. Data on cherries must be developed fran field trials in California, Michigan, New York/Pennsyl-
vania UtaI 4 ntaria/Idahe, and WashingtotVOregon. since cherries are to be subjected to both tol jar and bark
treatnEnt, residue data reflecting toliar and bark at the maximum application rates are required. Residue
data must include results fran treatnent with EC formulations, since residues uld be expected to be higher
frau that type of forimilation. It treatmant is limited to either toliar or bark treatnEnt (rather than both),
then revised labeling will be required. The dbsage rate for both fol jar and bark applications should be ex-
pressed in tenns of pounds per 100 gallons (lbs/100 gal) and as a range in pounds per acre (lbs/acre). The
dosage in ten’ns of lbs/acre is based on the number of gallons of dilute spray needed to spray one acre of
trees to the point of runoff (for foliar and bark treatment) or the equivalent anKunt of product per acre in
concentrate sprays (for foliar application only). A prohibition against grazing livestock on cover crops
beneath treated trees must be added to lindane end-use products with directions for use on cherries. Revised
labeling must be stinitted that specifies the total number of toliar applications permitted per season and
the interval between these applications.
60/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 ppn on nectarines
must be sukiuitted. The data must be developed frau field trials in California, Pennsylvania, South Carolina,
xas, and shington. Appropriate labeling describing acceptable application methods and rates, and any
limitations, pertaining to the use of lindane on nectarines must also be sutmitted.
61/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 pj m on peaches must
be sthnitted. Data on peaches must be developed fran field trials in California, Michigan, New Jersey/Penn-
sylvania, Georgia/South Carolina and Washington. Since peaches are to be subjected to both foliar and bark
treatnent, residue data reflecting foliar and bark at the maximum application rates are required. Residue
data must include results frau treatment with EC tormulations, since residues uld be expected to be higher
fran that type of formulation. It treatment is limited to either toliar or bark treatment (rather than both),
then revised labeling will be required. With sane varieties of peaches, the 60 day pre—harvest interval (Pt-IT)
is not ccmpatible with the instructions not to apply later than 7 days after shuck split. Applications 60 days
before harvest could take place as long as 2 rronths atter shuck split for sa varieties. This discrepancy
must be eliminated by revising the E4 1I, which should reflect residue data t ran several varieties ot peaches
with different maturation dates. The dosage rate for both toliar and bark applications should be expressed
in terms of pounds per 100 gallons (lbs/100 gal) and as a range in pounds per acre (lbs/acre). The dosage in
terms of lbs/acre is based on the number of gallons of dilute spray needed to spray one acre of trees to the
point of runoff (for foliar and bark treatment) or the equivalent anount of product per acre in concentrate
sprays (for toliar application only). A prohibition against grazing livestock on cover crops beneath treated
trees must be added to lindane end-use products with directions for use on peaches. Revised labeling must be
suLinitted that specifies the total number of tol jar applications permitted per season and the interval between
these applications.
211
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S 158.125 Residue Ch nistry (continued)
62/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 PLIfl on plums must be
sthnitted. Data on peaches must be developed fran field trials in California, Idaho, Michigan, and Washington/
Oregon. Since plums are to be subjected to both foliar and bark treatment, residue data retlecting toliar and
bark at the maximun application rates are required. Residue data must include results f ran treatii nt with EC
formulations, since residues uld be expected to be higher frau that type of formulation. If treatment is
limited to either fol jar or bark treatment (rather than both), then revised labeling will be required. The
dosage rate for both foliar and bark applications should be expressed in terms of pounds per 100 gallons
(lbs/lO0 gal) and as a range in pounds per acre (lbs/acre). The dosage in terms ot lbs/acre is based on the
number of gallons of dilute spray needed to spray one acre of trees to the point of runoff (for toliar and
bark treath ent) or the equivalent anotint of product per acre in concentrate sprays (for toliar application
only). A prohibition against grazing livestock on cover crops beneath treated trees must be added to lindane
end-use products with directions for use on peaches. Revised labeling must be sut:znitted that specifies the
total number of tol jar applications permitted per season and the interval bet en these applications.
63/ Since plums can be processed in dried prunes, residue data on dried prunes is required in order to Uetermine
if a food additive tolerance is needed.
64/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 p xn on fresh prunes
must be sulinitted. Data on fresh prunes must be developed fran field trials in California, Idaho, Michigan,
and Washingtor Oregon. Since fresh prunes are to be subjected to both foliar and bark treatment, residue
data reflecting foliar and bark at the maximum application rates are required. Residue data must include
results fran treatment with EC formulations, since residues uld be expected to be higher t ran that type of
formulation. If treatment is Limited to either foliar or bark treatment (rather than both), then revised
labeling will be required. The dosage rate for both foliar and bark applications should be expressed in
terms of pounds per 100 gallons (lbs/l00 gal) awl as a range in pounds per acre (lbs/acre). The dosage in
terms of lbs/acre is based on the number of gallons of dilute spray needed to spray one acre of trees to the
point of runoff (for foliar and bark treatnent) or the equivalent an unt of product per acre in concentrate
sprays (for foliar application only). A prohibition against grazing livestock on cover crops beneath treated
trees must be added to lindane end—use products with directions for use on fresh prunes. Revised labeling
must be sthnitted that specifies the total number of foliar applications permitted per season and the interval
bet en these applications.
65/ Since fresh prunes are processed in dried prunes, residue data on dried prunes is required in order to deter-
mine if a food additive tolerance is needed.
66/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 p n on quince must
be si±initted. The data must be developed fran field trials in California. Appropriate labeling describing
acceptable application methods awl rates, awl any limitations, pertaining to the use ot 1 indane on quince
must also be sthnitted.
67/ A group tolerance is not appropriate at this time because adequate residue data are not available for repre-
sentative crops of this graip (blackberry or other Rubus , blueberry, cranberry, grapes, and strawberry)
and the metaboli n of lindane in plants is not adequately understood.
212
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S 158.125 Residue Ch nistry (continued)
68/ Residue data in the form of a pesticide petition to support the current tolerance of 1 • 0 pr’ on grapes must be
sutinitted. Data on grapes must be developed fran field trials in California, Michigan, New York, Washington,
and North Carolina. These data should reflect the maximun current use. Residue data must include results tran
treatn nt with EC formulations, since residues wuld be expected to be higher fran that type of formulation.
Revised labelir must be sutinitted that gives the application rate in terms of pounds of active ingredient per
acre and that spec if les the total nunber of applications permitted per season and the interval between these
applications.
69/ Residue data are required on wet and dry grape panace and raisin waste in order to determine whether teed
additive tolerances are needed. Residue data are required on grape juice and raisins in order to determine
whether food additive tolerances are necessary.
70/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 pj n on strawberries
must be sutinitted. Data on strawberries must be developed tran field trials in California, Florida, New York/
C*iio, oregor /Washington, Indiana/Michigan, and Louisianna. Since strawberries are to be subjected to both
soil and toliar treatment, residue data reflecting both soil and foliar treatments at the inaximun application
rates are required. Residue data must include results fran treatment with EC formulations, since residues
uld be expected to be higher f ran that type of formulation. If treatment is limited to either soil or
foliar treath nt (rather than both), then revised labeling wiLIl be required. Revised labeling that specifies
the total nunber of fol jar applications permitted per season and the interval between these application must
be sutinitted.
71/ A group tolerance is not appropriate at this time because adequate residue data are not available tor repre-
sentat ive crops of this group (alnonds, pecans, and English walnuts) and the metabol i&n ot 1 indane in plants
is rot adequately understood.
72/ Residue data in the form of a pesticide petition to support the current tolerance of 0.01 p m on pecans must
be sutinitted. Data on pecans must be developed fran field trials in UDuisianna, Texas/New Mexico/Oklahcina.
These data should reflect the maximun current use and application of representative formulations. In order
to effectively extract residues of lindane, the nuts slould be ground in an ultra Centitugal Mill before
extraction with a Lolyton or Qin i-Mixer. Samples should not be frozen and stored prior to analysis because
no storage stability data for residues of lindane on pecans are currently available.
73/ A group tolerance is not appropriate at this time because adequate residue data are not available for repre-
sentative crops of this group (corn - fresh sweet corn and dried field corn, rice, sorghun, and wheat) and
the metaboliau of lindane in plants is not adequately understood.
74/ Seed treatment is considered to be a food use, unless a radiolabeled study has shown there is no transfer of
radioactive residues fran the seed to the aerial port ions of the plant. An appropriate tolerance (supported
by adequate residue data fran Idaho/Montana/North Dakota/Washington, Calitornia, Minnestoa, and Maryland)
should be proposed for residues of 1 indane on barley Ci .e., the second generation of barley grain) arising
f ran the treath nt of barley (seed) grain. Alternatively, a radiolabeled study showing the degree of transfer
of residues fran the seed to aerial portions of the plant could be used to support the position that barley
grain treatment is a non-food use that does not require a tolerance. Since barley torage, hay, and straw are
feed itans, it will also be necessary either to sutxnit residue data on forage, hay, IContinued on next page]
213
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S 158.125 Residue Ch nistry (continued)
74/ IContinued frau previous page] and straw grown fran treated seed or to sutinit revised labeling that prohibits
the feeding of barley forage, hay, and straw to livestock. Recaiu ndations for tank mixes of lindane with
other pesticides not having established tolerances on barley must be raioved fran labeling.
75/ If detectable rounts of lindane are found in barley (that is, in second generation barley grain) after seed
treatu nt at exaggerated rates, a milling study and data on residue in the germ will also be necessary. It
the required plant metabo1i n studies indicate the presence of other residues besides parent lindane, and if
significant levels of these riQtabolites are found in secor i generation barley grain, then a processing Study
uld be required to determine if these residues concentrate in processed catuodities.
76/ Seed trea nt is considered to be a food use, unless a radiolabeled study has shown there is no transfer of
radioactive residues fran the seed to the aerial portions of the plant. Art appropriate tolerance should be
proposed for residues of lindane on corn grown f ran treated seed. Since the use is on the camiodity “corn”,
residue data for field corn, sweet corn, and popcorn are required. Residue data on sweet corn (including
kernals plus cobs with husks r noved) grown f ran treated seed are required f ran Florida, California, New York,
Texas, Ohio/Pennsylvania, Massachusetts/New Jersey, oregon/washington/Idaho, Michigan/Minnesota/Wisconsin,
and Illinois. Residue data on field corn grown fran treated seed are required f ran all areas across the
country. Residue data on popcorn grown fran treated seed are required f ran Indiana/Illinois/Ohio, Kentucky,
Alternatively, a radiolabeled study showing the degree of transfer of residues fran the seed to aerial portions
of the plant could be used to support the position that corn grain treath ent is a non—food use that does not
require a tolerance. Residue data on forage and fodder f ran second generation popcorn and field corn are
required as well as residue data on forage f ran second generation sweet corn. Recamiendations for tank mixes
of lindane with other pesticides not having established tolerances on corn must be r toved frau labeling.
77/ If detectable lindane residues on second generation corn result f ran seed treatu nt at exaggerated rates, a
milling study will be required. If the required plant metaboli u studies indicate the presence of other
residues besides parent lindane, and if significant levels of these netabolites are found in second yener—
at ion corn, then a processing study uld be required to determine if these residues concentrate in processed
caivodities. Since it has been shown that lindane does not survive the hydrogenation or cieodorization steps,
a food additive tolerance will not be necessary for refined corn oil f ran second generation corn, if it is
established that corn oil is always deodorizeci and/or hydrogenated during the refining process.
78/ Seed treatn nt is considered to be a food use, unless a radiolabeled study has shown there is no transfer of
radioactive residues fran the seed to the aerial portions of the plant. An appropriate tolerance should be
proposed for residues of lindane on oats grown f ran treated grain (seed). Residue data on oats grown trait
treated seed are required fran Kansas/Iowa, Michigan/Wisconsin/Il 1 inois, rth Dakota/South Dakota/Nebraska,
and Pennsylvania/ohio. Alternatively, a radiolabeled study showing the degree of transfer of residues t ran
the seed to aerial portions of the plant could be used to support the position that oat grain treatment is a
non-food use that does not require a tolerance. Since oat forage,hay and straw are feed it ns, will also be
necessary to either sutinit residue data on forage, hay, and straw grown f ran treated oat seed or to sutxnit
revised labeling that prohibits the feeding of oat forage, hay, and straw to livestock. Since oat hulls are
a feed itan, residue data are required for cat hulls in order to determine whether a feed additive tolerance
is necessary. Recatmundations for tank mixes of lindane with other pesticides not having established toler-
ances on oats nust be reioved fran labeling.
214
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S 158.125 1 sidue Chenistry (continued)
79/ If detectable lindane residues on second generation oats result fran seed treatment at exaggerated rates, a
milling study will be required. If the required plant metaboli n studies indicate the presence ot other
residues besides parent lindane, and if significant levels of these metabolites are found in second genera-
tion oats, then a processing study would be required to determine if these residues concentrate in processed
ccmdities.
80/ Seed treatment is considered to be a food use, unless a radiolabeled study has shown there is no transfer of
radioactive residues fran the seed to the aerial portions of the plant. An appropriate tolerance should be
prcposed for residues of lindane on rye grown tran treated grain (seed). Residue data on rye grown trcxn
treated seed are required fran field trials in Georgia/North Carolina/South Carolina, Michiyary’Minnesota,
North Dakota/South Dakota/Nebraska, and nnsylvania/New York. Alternatively, a radiolabeleci study showing
the degree ot transfer of residues t ran the seed to aerial portions of the plant could be used to support
the position that rye seed treath nt is a non—food use that does not require a tolerance. Since rye forage
and straw are feed itens, it will also be necessary either to sutinit residue data on forage and straw grown
f ran treated rye seed or to sutinit revised labeling that prohibits the feeding of rye forage and straw to
livestock. 1 caiv ixIations for tank mixes of lindane with other pesticides not having established tolera :e
on rye must be rei ved f ran labeling.
81/ If detectable lindane residues on second generation rye result fran seed treatment at exaggerated rates, a
milling study will be required. If the required plant metabo1i n studies indicate the presence ot other
residues besides parent lindane, and if significant levels of these metabolites are found in second genera-
tion rye, then a processing study would be required to determine if these residues concentrate in processed
caimodities.
82/ Seed treath nt is considered to be a food use, unless a radiolabeled study has shown there is no transfer ot
radioactive residues fran the seed to the aerial portions of the plant. An appropriate tolerance should be
proposed for residues of 1 indane on sorghum grown f ran treated grain (seed). Residue data on sorghLln grown
f ran treated seed are required f ran field trials in Texas/Arkansa/Oklahana, Kansas/Missouri, and Georgia/
Mississippi. Alternatively, a radiolabeled study showing the degree of transfer of residues f ran the seed to
aerial portions of the plant could be used to support the position that sorghum seed treatment is a non—food
use that does not require a tolerance. If seeds of sweet sorghum are to be treated with 1 indane, then a
separate tolerance for this catiiodity would be required. Since sorghum forage, fodder, and hay are feed
itens, it will also be necessary either to sufinit resiaue data on sorghum forage, fodder, and hay grown f ran
treated seed or to subeiit revised labeling that prohibits the feeding of rye fo :aje and straw to livestock.
I ccit ndations for tank mixes of lindane with other pesticides not having establisned tolerances on sorghum
must be r noved frau labeling.
83/ If detectable lindane residues on second generation sorghum result t ran seed treatnent at exaggerated rates,
a milling study will be required. If the required plant metaboli n studies indicate the presence of other
residues besides parent lindane, and if significant levels of these netabolites are found in second genera-
tion sorghun, then a processing study would be required to determine if these residues concentrate in proc-
essed caiucdities.
215
-------
S 158.125 1 sidue Ch nistry (continued)
84/ Seed treatment is considered to be a food use, unless a radiolabeled study has shown there is no transfer of
radioactive residues fran the seed to the aerial portions of the plant. Ait appropriate tolerance should be
proposed for residues of 1 indane on wheat grown fran treated grain (seed). 1 sidue data on wheat grown trail
treated seed are required fran field trials in all areas across the country. Alternatively, a radiolabeled
study showing the degree of transfer of residues fran the seed to aerial portions of the plant could be used
to support the position that wheat seed treathent is a non—food use that does not require a tolerance. Since
wheat forage, straw, and hay are feed itans, it will also be necessary either to sulinit residue data on forage,
straw, and hay grown fran treated wheat seed or to sutinit revised labeling that prohibits the feeding of wheat
forage and straw to livestock. Recatinendations for tank mixes of 1 indane with other pesticides not having
established tolerances on wheat must be r ved f ran labeling.
85/ If detectable lindane residues on second generation wheat result fran seed treatment at exaggerated rates, a
milling study will be required. Although sane milling studies on wheat have been carried out, these studies
involved grain which had been treated and then milled. s piking and processing a cantodity is not generally
acceptable when the pesticide is systanic. Since lindane is systanic, the residues found in second generation
wheat * ild result t ran translocation and not just f ran surface residues. If the required plant metaboli n
studies indicate the presence of other residues besides parent lindane, and it significant levels of these
metabolites are found in second generation wheat, then a processing study uld be required to determine it
these residues concentrate in processed ccm odities.
86/ A group tolerance is not appropriate at this tune because adequate residue data are not available for repre-
sentative crops of this group (bermuda grass, bluegrass, and branegrass or fescue) and the metabolisn of
lindane in plants is not adequately understood.
87/ Seed treatment is considered to be a food use, unless a radiolabeled study has shown there is no transter ot
radioactive residues fran the seed to the aerial portions of the plant. An appropriate tolerance should be
proposed for residues of lindane on suian rass grown trait treated seed. Residue data on sudangrass grown
fran treated seed are required fran field trials in California and Texas. Alternatively, a radiolabeled
study showing the degree of transfer of residues f ran the seed to aerial portions of the plant could be used
to support the position that sudangrass seed treatment is a non—food use that does not require a tolerance.
Since sudangrass hay is a feed itan, it will also be necessary to sutinit residue data on sudangrass hay grown
fran treated seed. Reca inendations for tank mixes of lindane with other pesticides not having established
tolerances on sudangrass must be r noved f ran labeling.
88/ A group tolerance is not appropriate at this time because adequate residue data are not available tor repre-
sentative crops of this group (alfalfa and clover) and the metabolism of lindane in plants is not adequately
understood.
89/ Seed treatment is considered to be a food use, unless a radiolabeled study has shown there is no transfer of
radioactive residues f ran the seed to the aerial portions of the plant. An appropriate tolerance should be
proposed for residues of lindane on alfalfa grown fran treated seed. Residue data on alfalfa seed, forage,
and hay grown fran treated seed are required fran field trials in all major alfalfa growing areas of the
country. Alternatively, a radiolabeled study s1u ing the degree of transfer of residues t ran the seed to
aerial portions of the plant could be used to support the position that alfalfa [ Continued on next page]
216
-------
S 158.125 Residue (1 nistry (continued)
89/ [ Continued trau previous page] seed treathient is a non-food use that does not require a tolerance • i ccim n—
dations for tank mixes of lindane with other pesticides not having established tolerances on alfalfa must be
ratoved fr a n labeling.
90/ Seed treatment is considered to be a food use, unless a radiolabeled study has shown there is no transfer of
radioactive residues trait the seed to the aerial portions of the plant. An appropriate tolerance should be
proposed for residues of lindane on clover grown trait treated seed. Residue data on tresh clover and hay
grc m fran treated seed are required fran field trials in all major clover growing areas of the country.
Alternatively, a radiolabeled study showing the degree of transfer of residues trait the seed to aerial por-
tions of the plant could be used to support the position that clover seed treatment is a non—food use that
does not require a tolerance. Recatrerxlations for tank mixes of lindane with other pesticides not having
established tolerances on clover must be ratoved fran labeling.
91/ Residue data in the tofu of a pesticide petition to support the current tolerance of 1.0 p in on asparagus must
be sthnitted. The data must be developed fran field trials in California, Michigan, and Washingtor OregOn.
Revised end—use product labeling must be sutinitted revising the limitation against using beyond the seedling
stage, which is too vague, to a prohibition against using lindane on plants beyond a certain height. Also,
the total nunber of application during the post—cutting stage and the interval bet en applications should be
specified.
92/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 p xn on avocados must
be sttinitted. The data must be developed trait field trials in California and Florida. Appropriate labeling
describing the application method and rate, and any limitations, pertaining to the use of lindane on avocados
must also be sukxnitted.
93/ Seed treatment is considered to be a food use, unless a radiolabeled study has s1 in there is no transfer of
radioactive residues fran the seed to the aerial portions of the plant. An appropriate tolerance should be
proposed for residues of lindane on second generation cottonseed grown f ran treated seed. Residue data on
cottonseed grown fran treated seed are required f ran field trials in Texas/Arizona/Okiahana, California, and
touisianWMississippi/Arkaflsa. The residue data should reflect maximtxa application rates on undelinted seed.
Alternatively, a radiolabeled study showing the degree of transfer of residues t ran the seed to aerial por-
tions of the plant could be used to support the position that cottonseed treatxent is a non—food use that
does not require a tolerance. Since cotton torage is a teed itan, it will also be necessary either to sutinit
residue data on forage grown f ran treated seed or to sutznit revised labeling that prohibits feeding cotton
forage to livestock. A label restriction prohibiting the feeding of cotton gin trash to livestock is needed.
Reccmlerbdaticfls for tank mixtures of liridane with other pesticides not having established tolerances on cotton
must be ratoved fran labeling.
94/ If real residues of lindane occur on cottonseed as a result of seed treatment at exaggerated rates, a processing
study including analyses ot hulls, meal, soapstock, and oil will be required. If concentration occurs in any
by—product, food/teed additive tolerances will be necessary. A food additive tolerance will not be necessary
for refined cottonseed oil fran second generation cotton, since it has been shown that residues of 1 indane do
not survive the hydrogenation of deodorization step in the ref inanent of oil. If the required plant metabolian
studies indicate the presence of other residues besides parent, and if significant levels of these metabolites
are found in second generation cottonseed, then a processing study will be required to determine if these
residues concentrate in processed ccnitodities.
217
-------
§ 158.125 Residue Ch nistry (continued)
95/ Seed treatment is considered to be a food use, unless a radiolabeled study has shown there is no transfer of
radioactive residues fran the seed to the aerial portions of the plant. i n appropriate tolerance should be
proposed for residues of lirxlane on flax grown fran treated seed. Residue data on tlax grown fran treated
seed are required fran field trials in North Dakota/South Dakota/Montana, MichigarVwisconsin, and Texas.
Alternatively, a radiolabeled study showing the degree of transfer of residues fran the seed to aerial por-
tions of the plant could be used to support the position that flax seed treatment is a non-food use that
does not require a tolerance. Since flax straw is a feed item, it will also be necessary either to sutmit
residue data on flax straw grown fran treated seed or to sutxnit revised labeling that prohibits teeding tlax
straw to livestock. Reccmi ndations for tank mixtures ot ].indane with other pesticides not having established
tolerances on flax nust be r )ved f ran labeling.
96/ If real residues of liixiane occur on second generation flax seed as a result of seed treatment at exaggerated
rates, a processing study will be required. Analyses of hulls and meal will be required. If concentration
occurs in any by—product, food/feed additive tolerances will be necessary. If the required plant metabolian
studies indicate the presence of other residues besides parent, and it significant levels ot these metabolites
are found in second generation flax seed, then a processing study will be required to determine if these
residues concentrate in processed caai dities.
97/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 p zn on guavas must
be sttinitted. The data must be developed fran field trials in Hawaii. Appropriate labeling describing the
application method and rate, and any limitations, pertaining to the use of lindane on guavas must also be
suIit itted.
98/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 pL ’ on mangoes must
be si*iiiitted. The data must be developed fran ield trials in Hawaii and Florida. Appropriate labeling
describing the application nuthod and rate, and any limitations, pertaining to the use of lindane on mangoes
must also be sitinitted.
99/ Residue data in the form of a pesticide petition to support the current tolerance of 3.0 pjiin on mushroat must
be suthiitted. The data must be developed fran field trials in California, Illinois/Missouri, and I nnsylvania.
Appropriate labeling describing the application method and rate, and any limitations, pertaining to the use of
lindane on mushroans must also be sutinitted.
100/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 p in on okra must be
sttuitted. The data must be developed fran tield trials in Florida/Georgia/Alabana and Texas. Since both
seed treathunt and soil applications are permitted, residue data reflecting collectively both mzxles of appli-
cation at the maxiinun application rates are required. If it can be shown that seed treatment results in
negligible residues in the edible portion ot the plant, then residue data reflecting soil application at
the maxiiuun application rate ild be adequate. Alternatively, it use is limited either to seed or to soil
application, then revised labeling showing only one method ot application will be required. Fecaiinendations
for tank mixes of lindane with other pesticides not having established tolerances on okra must be r oved
fran labeling.
218
-------
S 158.125 Residue Chanistry (continued)
101/ Residue data in the form of a pesticide petition to support the current tolerance of 1.0 ppn on pineapple must
be sulznitted. The data must be developed fr an field trials in Hawaii. Residue data on pineapples, bran, and
forage (including the crc ijns), and pineapple juice (see processed food data requiraiients below) utilizing
current analytical netfxxlology are needed. The residue data should reflect the maximtxn application rates of
representative formulations and should reflect pre-plant application, drip irrigation and foliar application.
If treated forage is not be fed to livestock, a revised label with such a prohibition is required. Recarn n—
dations for tank mixtures of lindane with other pesticides not having established tolerances on pineapples
nust not appear on labeling.
102/ Residue data on pineapple juice utilizing current analytical methodology are needed to determine if residues
concentrate in the juice, which uld necessitate a food additive tolerance. The residue data should reflect
the maxi.mun application rate to Hawaiian pineapples and should reflect preplant application, drip irrigation
and foliar application. Representative formulations should be applied to generate the residue data.
103/ Seed treatment is considered to be a food use, unless a raciiolabeled study has sF n there is no transfer of
radioactive residues fran the seed to the aerial portions of the plant. An appropriate tolerance should be
proposed for residues of lindane on (second generation) safflower seed grown trait treated safflower seed.
Residue data are required frau field trials in Arizona, Calitornia, and South Dakota/Montana. Alternatively,
a radiolabeled study showing the degree of transfer of residues fran the seed to aerial portions of the plant
could be used to support the position that safflower seed treatment is a non—food use that does not require a
tolerance. Recai ndations for tank mixtures of lindane with other pesticides not having established toler-
ances on safflower seed must be r ved fran labeling.
104/ If real residues of lindane occur on (second generation) safflower seed as a result of seed treatment at exa jger—
ated rates, a processing study will be required. Analyses of meal and oil will be required. It concentration
occurs in any by—product, food/feed additive tolerances will be necessary. If the required plant metaboli n
studies indicate the presence of other residues besides parent, and if significant levels of these metabolites
are found in second generation safflower seed, then a processing study will be required to determine it these
residues concentrate in processed caim dities.
105/ Seed treath nt is considered to be a food use, unless a radiolabeled study has shown there is no transfer of
radioactive residues fran the seed to the aerial portions of the plant. An appropriate tolerance should be
proposed for residues of lindane on (second generation) sunflower seed grown fran treated sunflower seed.
Residue data are required f ran field trials in Texas, North Dakota/South Dakota/Montana, California, and
Kansas/Colorado. Alternatively, a radiolabeled study showing the degree of transfer of residues t ran the
seed to aerial portions of the plant could be used to support the position that sunflower seed treatment is
a non—food use that does not require a tolerance. Since sunflower forage is a food itan, it will also be
necessary either to suixuit residue data on sunflower forage grown f ran treated seed or to sthnit revised
labeling that prohibits feeding sunflower forage to livestock. Recatu ndations tor tank mixtures of lindane
with other pesticides rot having established tolerances on sunflower seed must be r ioved f ran labeling.
106/ If real residues of lindane occur on second generation sunflower seed as a result of seed treatment at exag-
gerated rates, a processing study including analyses of hulls, meal and oil will be required. If concentra-
tion occurs in any by—product, food/feed additive tolerances will be necessary. [ Continued on next page]
219
-------
S 158.125 1 sidue iianistry (continued)
106/ [ Continued fran previous page] A food additive tolerance will not be necessary for refined suntlowar oil
fran second generation sunf1c rier seed, it it is established that sunflc ier oil is always deodorized and/or
hydrogenated during the refining process. It has been shown that residues of 1 indane do not survive the
hydrogenation of deodorization step in the ref in nt of oil • If the required plant metaboli TI studies
indicate the presence of other residues besides parent, and if significant levels of these metabolites are
found in second generation sunflower seed, then a processing study will be required to determine if these
residue concentrate in processed caTlaxiities.
107/ The use of 1 indane on tobacco does not require a tolerance or an exanpt ion fran tolerance, but data are needed
to assess the exposure to residues resulting fran the use of lindane. There are no lindane resiaue data on
tobacco which reflect the present uses. Residue data fran field trials in Kentucky/Virginia/TennesSee, and
Georgia/North Carolina/South Carolina are required. Residue data reflecting application of the EC fornu.Lla-
tions should be included, as residues would be expected to be higher fran that type of formulation. Since
tobacco plants can be subjected to both foliar and transplant water treatment, residue data reflecting both
fol jar and transplant treatnEnt at the inaximun application rates are needed. If use is 1 united to fol jar
or transplant treatment (rather than both), revised labeling with this restriction must be sutinitted. A
residue çtofile on tobacco & ke is also required. It residues of 0.1 p in or Itvre are found on green freshly
harvested tobacco, pyrolysis products fran the active ingredient must be characterized. The total niinber of
foliar applications and the interval betwaen application should be specified in a revised label.
108/ ALL MED 0 JS OF APPLICA TI0N TO LIVE 1OCK
Available residue data do not support the tolerance of 7 p zn for residues of lindane in the fat fran cattle,
goats, horses, and sheep and 4 p in in the fat f ran hogs because much of the data ware generated by question-
able or unspecified n thods and nost of the studies did not specify the conditions under which the sanpies
ware stored or give the duration of the storage period before analysis. Residue data using adequate metho-
dology must be sthnitted for residues of lindane in animal tat resulting f ran the various methods of applic-
cation and at appropriate dosages. Unless the requested animal metaboli n studies establish the absence ot
radioactive residues in other tissues, residue data on meat and meat by—products are needed in order to estab-
lish tolerances on these ccniiodities for residues of parent lindane. If animal metaboli&n studies reveal the
presence of other residues of toxicological concern besides parent lindane, residue data will also be required
for these residues.
SE AYS AND DIPS
The results of previous studies indicating the presence of lindane residues in cattle tat following spray
application of 0.075% lindane but not after application of 0.03% lindane need to be verified. The spray and
dip treatments impose no limit to the nunber of applications which can be made to livestock. A revised label
is required which specifies the nunber of applications permitted and the interval betwaen applications. The
treatment rate should be supported by adequate residue data. Pre—slauhter intervals of 30 days are imposed
following spray treath nt and 60 days following dip treatit nt. [ Continued on next page]
220
-------
S 158.125 Residue nistry (continued)
108/ [ Continued fran previous page] Pre—slaughter intervals greater than 3 days are not practical since animals
may be sent to slaughter over an extended period of time, and, if sold, the pesticidal history ot the animals
may not be known to the new owner. Residue data reflecting pre-slaughter intervals of 3 days or less are
required for spray and dip applications.
The airrent use permits the spraying and dipping of hogs. No residue data are available for the dipping
of hogs, bet sai ot the available data on cattle indicate that residues resulting fran dipping could
be higher than fran spray trea nt. Residue data reflecting analyses of tat tissue fran hogs which
have been dipped at the maximun application rate are required.
Available data indicate that unshorn laubs have much higher residues in the fat after dipping than shorn
sheep. ? re residue data on unshorn lanbs and sheep reflecting the maxinuin treatment rate are required to
support the tolerance.
Since dips and sprays may be formulated with toxaphene, labeling must include the n re stringent precautions
and restrictions associated with each of the pesticide cauponents involved in a ccznbination product.
PRESSURIZED S AYS
No residue data are available for the residue levels of lindane in livestock tat following spot treatment tor
screw—worme with the 3% 1 indane pressurized spray. No pre—slaughter interval is imposed following pressurized
spray application. Residue data reflecting use of the 3% pressurized 1 indane spray are required to support
the tolerance • Fat sanples reflecting various pre-slaughter intervals (including a zero day pre—slaughter
interval) sI xild be analyzed so that the b.iild—up and decay of lindane residues as a tunction of time after
treatment can be evaluated • The nunber of 3% 1 indane pressurized spray applications for the spot treatment of
screwworm infested livestock is not specified. Revised label is required which specifies the nunber of appli-
cations permitted. The treatment rate should be supported by adequate residue data.
SIttl TREATh
Although there are no residue data for animal sponge treatment, the requested residue data tor the use of the
pressurized spray treatment for the spot treatment ot screw-worms would cover residues arising f ran this appi i-
cation. The total number of application for this use should be specified in a revised label • In order to
extrapolate £ ran the requested residue data on the 3% 1 indane pressurized spray, the dosage for the animal
sponge treatment in terms of percent lindane is required.
[ Continued on the next page]
221
-------
S 158.125 1 sidue Chanistry (continued)
108/ [ Contiri.ied frau previous page]
There are no residue data available reflecting dust treatment of livestock. since the current use Imposes no
pre—slaughter interval, residue data reflecting dust treatn nt with a zero day pre—slaughter interval are
required to support the tolerance. Since dust treatments may be formulated with methoxychior, labeling must
inclixle the n re stringent precautions and restrictions associated with each or the pesticide caiiponents
involved in a cai bination product.
B CKRUBBERS, DUST B L3S, and RUBBING FOSTS
Residue data for backrubber use, dust bag treatment, or rubbing post treatment are required. Since the
animals uld have unlimited access to these devices, the experiment should be designed to maximize exposure.
Current labels indicate pre-slaughter intervals of 30 days following exposure to back rubbers. Pre—slaughter
intervals greater than 3 days are not practical as animals may be sent to slaughter over an extended period of
tune, and, if sold, the pesticidal history of the animals may not be known to the new owner. Residue data
reflecting pre—slaughter intervals of 3 days or less are required for backrubber applications.
109/ No tolerance has been established for residues of lindane in milk. Available residue data on the 3% pressurized
spray for the spot treatment of screw-wrins indicate that lindane residues are detected in milk up to 29 days
after a second treatment and 24 days after a single treatment. A tolerance for J.indane residues in milk will
have to be established unless revised labeling is sukxnitted for this type of product that prohibits use on
lactating dairy animals. Dairy cattle and dairy goats may be exposed to lindane by several direct or indirect
methods, therefore, a tolerance level for lindane residues in milk, based on adequate residue data, must be
proposed. This prcposed tolerance should be high enough to include residues arising fran ingestion as well as
dermal treatments applicable to dairy cattle and goats (i .e. pressurized spray treatment and animal sponge
treatment, dust treatment, and dust bag, back rubber or rubbing post applications). Alternatively, labeling
bearing restrictions against any method of application to lactating dairy animals (cattle and goats) should be
si.tinitted. However, since it is not possible for the ] gency to estimate the lindane dietary burden imposed
upon livestock until the required residue data on crops arid teed it tts have been sutxnitted and reviewed, a
tolerance for residues of lindane in milk may have to be established based upon dietary intake, even if all
direct applications were prohibited. Labeling for all lindane end-use products with directions tor use on
live stock prunises or farm txiildings must bear a prohibition against application in dairy barns.
110/ Tolerances have not been established for residues of lindane in poultry or eggs, h ver, it may be necessary
to establish such tolerances if significant levels of 1 indane are found in poultry teed itans. Label thy ot
all lindane end-use products with directions for use on livestock pr nises or tarn buildings must bear a
prohibition against application in poultry houses.
222
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§158.130 Enviroanental Fate
1 GRAJ rIaq STUDIES—L1 B :
161—1 — Hydrolysis
Photodegradat ion
161—2 — In ter
161—3 — On Soil
161—4 — In Air
METhBOLISM STUDIES—LAB :
162—1 — Aerobic Soil
162—2 — Anaerobic Soil
162—3 — Anaerobic uatic
162—4 — Aerobic aquatic
P JBILI1Y STUDIES :
163-1 - Leaching and
MsorptioVDesorpt ion
— Volatility (Lab)
— Wlatility (Field)
or PAIRA
or PAIRA
or PAIRA
or PAIRA
27 Months
27 Months
1/ Use 2/
Data 1 quiraient Canposit ion ttern
TABLE A
G&4ERIC 1 TA RFr (JIRE lEN S FtR LINt NE
IXes EPA
Have Data
lb Satisfy
This
RequiraTlent?
Must Additional
Data Be
Time
Bibliographic
Citation
Sut iitted
Under FIFRA
§ 3(c)(2)(B) ?
Frame
For Data 3/
Sutxaission
l I or PAIRA A,B,E,F,G,H,K,L
or
or
or
PAIRA
PAIRA
PA l PA
Yes 9 Months
1 I
T I
T I
T I
1t I
l I
TGAI
A,B,G
A,G
A
A B, E ,G, K
A
No
No
No
No
No
9 Months
9 Months
Yes
Yes
Peserved4/
Yes
Yes
No 5 !
No 5 !
163—2
163—3
l AI or PAIRA A,B,E,F,G,H,K,L No
TEP A,E,F,J,K No
TEP A,E,F,J,K No
Yes 12 Months
Yes
Reserved 6/
12 Months
223
-------
- k uatic (Sedin nt)
Rrestry
ambinat ion and
Tank Mixes
CCL ULXIIC1 1 SIUDIE :
165—i — i tationai Crc.ps
(confined)
165—2 - 1 tationa1 crcps
(Field)
- Irrigated crcps
— In Fish
— In Aquatic Non—target
Organi&ns
A,B,H No
5/
G,L No
1/
Data 1 quir nt canLxsition
TABLE A
4ERIC L1 EA REI UIRF24 N1’S I DR LIN1 NE
Does EP
Have Data
Use 2/ lb Satisfy
Pattern This
1 quir nt?
Must iditional
Data Be
Thre
Bibliographic
Citation
S
Sutinitted
Under FIFRA
3(c)(2)(B)
.
?
For Data 3/
SutxniSsi ofl
S158.130 Envirorinental Fate (continued)
DISSIPATICt SflJDIES-FIELD :
164—1 — Soil
164—2
164—3
164—4
TEP
TEP
TEP
164—5 — Soil, LDr j—tenn
165-3
165—4
165—5
TEP A No
PAIRA A No
TEP A No
TEP A No
l AI or PAIRA A,B,G,L No
TEP G,L No
Yes 27 t4cnths
No 5 !
yes 7 ! 27 !‘t nths
8/
Yes 39 Dnths
1 served 9 /
yes 7 ! 39 Wnths
Yes 12 P4Dnths
10/
224
-------
TABLE A
G ERIC IY IIA REOUIRE2IENIS RDR LINE1 NE
Data Requir ient
/
Canposition
Use 2/
ttern
Dues EPA
Have Data
lb Satisfy
This
R equir nent?
Bibliographic
Citation
S
ttlst dditiona1
Data Be
Sutinitted
Under FIFRA
3(c)(2)(B) ?
Time Fra ne
For Data
Suttuission
S158.130 F wirorinenta.l Fate
(continued)
RE—ENIRY SIUDIES:
132-1 F liar Dissipation
TEL)
A ’ 1 !
No
-
Yes
27 nths
EXIOSURE STUDIES:
Applicators
TEP
12/, 13/,
14/, 15/
No
—
Yes
6 Zt)nths
Residents
TEP
16/, 17/
No
—
Yes
6 tt nths
Human skirVclothing
1% Dust
18/
No
—
Yes
6 Months
1/ Qinposition: 1 AI = Technical Grade of the Active Ingredient; PAIRP = Pure Active Ingredient, Radio-labelled;
TEP = l ypical Did—Use Product.
2/ The use patterns are coded as follows: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food, C=Aquatic, Food Crop,
D = 1 uatic, Non—Food; E = Greenhouse, Food Crop; F = Greenhouse, Non—Food; G = Forestry; H = IXinestic Outdoor;
I = Indoor; J = Caiiiercial Indoor; K = Animals/Pr nises; L = Lumber
3/ Due dates refers to number of months following receipt of this Registration Standard.
4/ Reserved, pending receipt and evaluation of data on photodegradation in water, photodegradation on soil, and
aerobic soil xnetaboli u.
5/ No registered aquatic uses.
6/ Reserved, pending receipt and evaluation of laboratory volatility data.
7/ May be canbined with tests for field accumulation, aquatic non—target organi us, per 165—5.
8/ Required only if residues found, per 164—1, exceed 50% of applied at time of subsequent application.
9/ Reserved, pending receipt and evaluation of studies tran confined rotational crop study.
10/ Required only if laboratory fish accumulation study show a potential tor residue accumulation.
225
-------
§158 .130 Enviromental Fate (Continued)
11/ For each crop whose agricultural practice requires prolonged, substantial contact with pesticide treated surfaces,
the registrant is required to propose an acceptable re-entry interval based on data on dissipation of foliar dis-
lodgeable residues of lindane (a declining curve),, on hi.inan exposure to those residues, and on toxicity of liFidane.
Registrants may submit protocols to the P ency for approval prior to initiating studies.
12/ Applicator exposure data must be submitted to support the fant r planter box method of seed treatment. Within 90
days of receipt of this Guidance DDcUnent, registrants must submit protocols for the appropriate exposure studies.
Results of the exposure studies must be submitted within 6 months of the I gency’ s approval of proposed protocols.
13/ Applicator exposure data must be submitted to support the livestock spray application uses. Within 90 days ot
receipt Ut this Guidance Docunent, registrants must submit protocols for the appropriate exposure studies. Results
of the exposure studies must be submitted within 6 months of the Agency’s approval of protocols.
14/ Applicator exposure data must be submitted to support the structural application uses. Within 90 days of receipt
of this Guidance rxcur nt, registrants must submit protocols for the appropriate exposure studies. Results ot the
exposure studies must be submitted within 6 months of the Agency’ S approval of protocols.
15/ Applicator exposure data must be submitted to support the dog wash, dog dust, and dog shampoo uses. Within 90 days
of receipt of this Guidance Docunent, registrants must submit protocols for the appropriate exposure studies.
Results of the exposure studies must be submitted within 6 months of the Agency’s approval of the protocols.
16/ Air monitoring data is required to support the structural application uses of lindane. Within 90 days of receipt
of this Guidance IX)cuuent, registrants must submit a protocol for an air monitoring study. Results ot the study
must be submitted within 6 months of the Agency’ s approval of the protocol.
17/ Air monitoring data is required to determine the exposure of residents following the treatment of dogs by lindane
wash, dust, or shaupoo. Within 90 days ot receipt ot this Guidance [ ocument, registrants must submit protocols
for air monitoring studies for the exposure of residents following the various treatment methods. Results of the
studies must be submitted within 6 months of the Agency’s approval of the protocols.
18/ Exposure data must be submitted to support the use on human skin/clothing by the military. Within 90 days of receipt
of this Guidance IX)ct ment, registrants must submit protocols for the appropriate exposure studies. Results of the
exposure studies must be submitted within 6 months of the Agency’ s approval of the protocols.
226
-------
S158.135 ibxi 1ogy
? Th l fl :
81—1 — ute al lbxicity
(rat)
81—2 — acute Dennal lbxicity
(rabbit)
81—3 — ute Inhalation lbxicity
(rat)
81—6 — Denn. 1 Sensitization
(guinea pig)
81—7 — Delayed Neurotoxicity
(hen)
SUBQ1 IC l rING :
82-1 - 90-Day F edii j:
— dent (rat)
— Non-rodent (dog)
21—Day Dermal (rabbit)
90—Day Dennal (rabbit)
90-Day Inhalation (rat)
90-Day Neurotoxicity
(hen)
/
Data Requirat nt c anpositiork
Use 2/
I ttern
TABLE A
GENERIC I Th RET JIRE iENrS FOR LINt NE
i) es EPA
Have Data
lb Satisfy
This
1 auiranent?
ttist Additional
Data Be
Tia Fra
Bibliographic
Citation
Sutinitted
Under FIFR
S 3(c)(2)(B)
?
Fbr Data j /
Sutinission
Yes 9 Zbbnths
]X AI
All
E rtia1ly
00049330
00109141
No
l I
All
Partially
00049330
00109141
No
]X AI
All
No
—
]EAI
Al].
—
N .A.
All
00128356
All
All
82—2 —
82—3 —
82—4 —
82—5 —
No
Yes
No
No
NO
No
l I
T I
T I
l I
l I
N .A.
Yes
No
No 4 !
yes5/
yes 6 !
Yes 7 !
9 tbnths
12 Months
15 Months
15 W,nths
E, F, I
227
-------
TABLE A
GFNERIC t1 iIA R UIRF iFN1’S FOR LINIW E
lXes EPA
Must l iditiona]
Have Data
Data Be
Time Frai
Data
Raquirefl nt
1/
Canpos it ion
Use 2/
r ttern
‘lb Satisfy
This
Raquirauent?
Bibliographic
Citation
Sutinitted
der FIFRA
S 3(c)(2)(B)
?
r Data 3/
SULITL1SS iOn
S158.135 Itxicology — O3ntinued
i t IC TFSTING :
83—1 — thronic ibxicity
2 species:
— Rident (rat) 1 i A,E No Yes 50 tt)nths
— Non—rodent (dog) 1t AI A,E Yes GS0315011 No
GS031501 2
GS0315013
83—2 — Cricogenicity
2 species:
— Rat TGAI A,E rtia11y 00142564 Yes 50 nths
00105313
GS0315016
GSO3 15017
A,E Yes GS0315017 No
0315018
GS0315019
GS0315020
GSO3 15021
GS0315022
00078916
83—3 — ‘ l rat o genicity
2 species
— Rat 1 I All Yes GS0315024
— Rabbit TGAI All Yes GS0315025 NO
83—4 — Raproduction (rat) A,E Yes GS0315026
2-generation
228
-------
TABLE A
G 4ERIC DATA RFX IJIRF iENIS L tiR LINDANE
Data 1 quirenent
1/
Q:inposition
Use
ttern
2/
1 es EPA
Have Data
lb Satisfy
This
I quirenent?
Bibliographic
Citation
ist ditional
Data Be
Sutinitted
Under FIFRA
§ 3(c)(2)(B) ?
Time Fra e
For Data 3/
Sutiuission
§158.135 lbxicology — ntinusd
PtJT ICITY TESTING
84—2 — Gene ?&itation (ki s l st)
l 3AI
All
.
Yes
00142715
No
84—3 — Stri.ctural thra sanal
Aberration
l’GAI
Afl
Yes
00143513
No
84—4 — Other Genotoxic Effects
TGAI
All
Yes
00143513
No
S CIAL TESTING
85-1 - General tabo1ian
PAl or PAIRA
A,E
Yes
00128538
GS031503 1
No
- Blood r ’scrasias
l’GAI
All
No
-
Yes 8 !
— Dermal Absorption
PAl or PAIRA
All
Yes
00031050
No
1/ Q:lnposition: PAl = Pure Active Ingredient; PAIRA = Pure Active Ingredient, Radiolabelled
2/ The use patterns are coded as fo1lc is: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food;
C = N uatic, Food Crop; D = Aqautic, Non-Food; E = Greenhouse, Food crop; F = Greenhouse, Non-Food;
G = Forestry; H = 1fli stic Gutdoor; I = Indoor
3/ Data must be st nitted within the indicated time frame, based on the date of the Guidance Document.
4/ See thronic l’bxicity (dog).
5/ 1 quired to support use patterns that do not require protective clothing and which might result in repeated
hi.t n skin contact (sixth as the use on cucurbits).
6/ L quired to support the use involving application to human clothing.
7/ 1 guired to support the greenhouse (food and non-food crops) y j indoor uses and also the use on human clothing.
8/ I gistrants responsible for developing generic data must meet with the Agency to develop an acceptable protocol
to establish an appropriate ti.zme frame for this stndy.
229
-------
S158.145 Wildlife and
Nluatic Organi
AVIAN A ) MNI4ALIAN TESTING
70-1 ecia1 Test
71-1 - ojte Avian al lbxicity
71-2 - Avian SLbawte Dietary
lbxicity
- 1and G Bird
— i terf i1
- Upland GalE Bird
- passerine Bird
- Wild Mnri 1 lbxicity
- Avian prcx ction
- Upland GalE Bird
— terfcwil
71—5 — Siimilated Field Testing
— Birds
71—5 — k tual Field Ibsting
-Birds
Reserved 4 !
yesS/ 9 Nonths
No
No
yes 6 /
yes6/
No
/
Data Requira Ent Ccinposition
Use2/
Tettern
TABLE A
G SRIC I TA RE UIRF 2fl’S FDR LINDANE
IXes EPA
Have Data
lb Satisty
This
Reauiranent?
ftzst Niditionai.
Data Be
TIme Fraie
Bibliographic
Citation
S
sutxnitted
Under FIFRA
3(c)(2)(B)
?
Fbr Data 3/
SutxnissiOfl
00020560**
00022923*
00022923*
71—3
71—4
TEP
A
No
l AI
A,G
rtially
TGAI
A,G
Yes
TGAI
A,G
Yes
TEP
A
No
TEP
A
No
T I
l I
T I
l I
9 t.t3nthS
9 Pbnths
A,G
No
A
No
-
Reserved 7 !
A
No
-
i served 7 /
TEP
A
No
TEP
A
No
Reserved 91
230
-------
- b rm ter Fish Species
72—2 — Acute lbxicity to
Fresi ater Invertebrates
72-3 - Acute lbxicity o Estuarine
and Marine Organians
— Fish
— ?bilusk
- Shrmp
TABLE A
14ERIC 1 TA RE UIRE N S FOR LINt NE
IXes EPA
Have Data
‘lb Satisfy
This
1 quirai nt?
Yes 1 1/ 9 t’bnths
Yes 1 1/ 9 lt nths
1/ Use
2/
[ eta 1 quir nt cxmpas it ion ttern
Bibliographic
Citation
Must 1ditionaJ.
Data Be
Sut:iuitted
Urxier FIFRA
S 3(c)(2)(B) ?
Tiii Frane
I br Data 3/
Sutinission
§158.145 Wildlife and
k iatic gani Kbntir*ied)
UATIC OR ANI ( 1 flNG
70—i — Special lest
72—i — Acute lbxicity to
Frest ,ater Fish
— Qid ter Fish Species
Yes 10 ! 12 Munths
Yes 11 ! 9 t’ nths
TEP A No
l AI A,G Yes
TEP A No
TGAI A,G Yes
TEP A No
l AI A,G Yes
TEP A No
A No
A
A
GS0144012* No
GS0144012* No
00097842** No
05017538**
GS0144012*
No
Yes l 2 !
No
12 t.bnths
231
-------
72—7 - Siniilated Field Testing
— kjuatic Organi3ns
— tual Field Testing
— Aquatic ( ganiai
TABLE A
( 4ERIC 1 TA R UIR flS FOR LINIW4E
Does EPA
Have Data
lb Satisfy
This
1 quiru ent?
/
Data Bequirai nt Ccinposit ion
Use W
I ttern
Bibliographic
P3.ist kiditiOna.l
Data Be
sutjnitted
W1er FIF A
S_3(c)(2)(B)_2
Tiu Frai
For Data 3/
SuLinissi ofl
Citation
§158.145 Wildlife and
Aajiatic Orqani (Cbntiri.ied)
? UATIC CNI 4 1 IPG (continued)
72-4 — Fish Early Life Stage
— Estuarine
- Freshb ter
— Aquatic Invertebrate
Life-Cycle
— Estuaririe
l I
A
No
l I
A
No
l I
A
No
I G AI
A
No
1W
A
No
72—5 —
72—6 —
- Fresh ter
Fish — Life —C le
Nluatic Organian
k aznulat ion
-Fish
No
Yes l 3 /
No
yes 13/
I served’ 4/
Yes lS/
15 Pbnths
15 Pbnths
12 t4xiths
1W A
TEP A
TEP A
No
NO
No
232
-------
S158 145 Wildlife and Aquatic Organians (ODntinued)
1/ Ocinposition of test material: i i = Technical Grade of the Active Ingredient; PAl = Pure Active Ingredient;
TEP = Typical End-use Product
2/ The t e tterns are coded as foll is: A = Terrestrial, Food Crop; B = Terrestrial, Non-Food;
C = Aquatic, Fbod Crop; D = Aquatic, Non-Rod; E = Greenhouse, Food Crop; F = Greenhouse, Non-Fbod;
G = F restry; H = Da stic Cxitdoor; I = Indoor
3/ All data must be submitted within the indicated time frane, based on the issue date of the Guidance Docunent.
4/ Residue monitoring of avian food itans may be needed to determine if there should be further restrictions to
reduce exposure of birds to 1 indane used in pecan orchards. The theoretical residue levels on vegetation
and insects exceed the avian risk criterion. This data requir nt is reserved pending Agency review of
the required studies on hydrolysis (161—1), photodegradation in water (161—2), and photodegraiaticn on soil
(161—3).
5/ The bobwhite quail shcxii.d be the test species for the avian single-dose oral acute toxicity studies.
6/ An additional set of avian dietary studies are needed to determine if birds will ingest lethal amounts ot
lindane when they cons .une treated seeds. The test species should be bobwhite quail and the red-winged
blackbird. In one test the birds should be exposed to a diet of Jindane treated seeds only, while in a
cai anion test they should be exposed to a choice of lindane treated and untreated seeds. Within 90 days
of the issue date of this Guidance Docunent, registrants must sulriit a proposed protocol for this study tor
Agency approval.
7/ This data requireierit is reserved pending Agency review of the required stuciies on photodegradation in water
(161—2) and pbotodegradation on soil (161—3), and the special residue monitoring study on avian food itans
(70—1).
8/ This data requiranent is reserved pending Agency review of the required studies on hydrolysis ( 161-1),
photodegradation in water (161—2), and photodegradation on soil (161—3), as wall as certain ot the avian
studies (70—1, 71—1, 71—2, and 71—4).
9/ This data requiranent is reserved pending Agency review of the required studies on hydrolysis (161-1),
photodegradation in water (161—2) photodegradation on soil (161—3), as wall as certain of the avian studies
(70—1, 71—1, 71—2, and 71—4). If a field study is needed, an actual field test can be done rather than a
simulated field test. Registrants must sutinit a proposed protocol for either study for Agency approval
within 90 days of the date of notification by the Agency that such data is being required.
10/ Aquatic residue monitoring is needed to determine if aquatic organians are exposed to lindane as a result
of the use in pecan orchards. This monitoring study must include both a runoff study and a spray drift
study (refer to 40 CFR 158.142) in order to determine the proportions of lindane residues entering
the aquatic ecosystan fran drift and fran ri.noft • Within 90 days of the date of this Guidance Dzcunent,
registrants must stbnit a proposed protocol for this study for Agency approval.
233
-------
S158.145 Wildlife and Nluatic Organi ns (Continued)
11/ Testing with a typical end—use product (TEP) is required when the acute toxicity to freshwater fish of the
technical grede material is equal to or less than the Estimated Envirorsi ntal Concentration (EEC) in the
aquatic enviror nt (such as for pecans and for soil and foliar applications on crops).
12/ The results fran the acute toxicity test with n l1usks will be used to determine the risk to erldark3ered
nol 1usks fran the use of 1 indane on pecan orchards.
13/ This requiranent is based on the acute toxicity to fish values of less than 1 milligraWliter and an
Estimated Envirormental Concentration (EEC) greater than 0.01 of any acute toxicity level to fish or
aquatic invertebrates.
14/ This data requira nt is reserved pending ilgency review of the required studies on h iro1ysis (161-1),
photodegradation in water (161—2), photodegradation on soil (161—3), aquatic residue nonitoring (70—1),
fish early life stage (72—4), and aquatic invertebrate life-cycle (72—4).
15/ The fish accumilation study required under 165-4 will also satisfy this requiranent.
16/ This data requiranent is reserved pending ency review of the required studies on h ro1ysis (161-1),
photodegradation in water (161—2), photodegradation on soil (161—3), aquatic residue nonitoriflg (70—1),
aa.ite toxicity to freshwater fish (72—1), acute toxicity to freshwater invertebrates (72—2), fish early
life stage (72—4), and aquatic invertebrate life—cycle (72—4). If the agency determines that a field
study is necessary, a iimi1 ated field study can be done rather than an actual field test. 1 gistrants must
sibnit a proposed protocol for either study for Njency approval within 90 days of the date of rotification
by the Agency that si.ch data is being required.
* This study alone fulfills the data requiranent.
** This study alone does rot fulfill the data requiranent.
234
-------
TABLE A
G lERIC
t tTA RF JIR 24ENIS F(R LINI NE
Does EPA
t4ist Piiditiona.l
Data
1 qjiirei nt
1/
O xsition
i e
I ttern
Have Data
lb Satisfy
This
B equira ent?
Data Be
Suth itted
aider FIFR
S 3(c)(2)(B) ?
Tii Frai
Fbr Data
Si.tiniss ion
Bibliographic
Citation
S158.150 Plant Protection
121 -4 — T AI A EP No
N Th r T1uK aCny
TIER I
122-1 — Seed Gennination/ 1 I No N o 2 /
Seedling rgence
122-1 - Wgetative Vigor l I No
122-2 - Aquatic Plant owth i i
TIER II
123-1 - Seed GenninatiolV l I No
Seedling Bi rgence
123-1 - Vegetative Vigor l A.I No
123-2 - Aquatic Plant ( owth l 3AI No No 2 /
TIER III
124-1 — Terrestrial Field TEP No
124—2 — Aquatic Field TEP No
1/ Catiposition: i i = TecJinjcal grade of the ective ingredient; TEP = Typical end—use product. EP = End-use product.
2/ These requira nts are generally wived unless it is believed there is a phototoxicity prthl n.
235
-------
TABLE A
GENERIC EY II R UIR 4I NI’S FOR LINDANE
IXes EPA
Must i iditiona.I
Have Data
Data Be
Data
1 quir ient
1/
Canposition
Use 2/
F ttern
Ib Satisty
This
1 quira nt?
Bibliographic
Citation
SutxnitteQ
Under FIFRA
§ 3(c)(2)(B)
?
For Data 3/
SuttfliSSiOfl
S158.l55 Nontarget Insect
NCC TA T INSECr TESTING —
FOLLINAiO1 :
141—1 — Honey bee acute A 4 ! Yes 00036935 NO
contact toxicity 05001991
141-2 — Honey bee - toxicity TEP A 4 ! No Yes 5 / 15 Honths
of residues on
fo1ia e
141-4 — Honey bee s acute [ I served] 6/
feeding study
141—5 — Field testing for TEP A 4 ! No NO 7 !
o1 linators
NCt Th1 r INSECT TESTING —
PQJATIC INSECIS :
142-1 — Acute toxicity to [ i served] 8 /
aquatic insects
142-1 — Aquatic insect [ I served] 8/
life—c c1e study
142-3 — Simulated or actual [ i served] 8/
field testing for
aquatic insects
236
-------
TA JEA
. ERIC 1 TA RF JIR *NlS FOR LINt NE
/
Data I quireusnt Ocinposition
L e /
I ttern
Ibes EPA
Have Data
lb Satisfy
This
Bequirenent?
Bibliographic
Citation
P st Additional
Data Be
Suth itted
er
S 3(c)(2)(B) ?
Thus Fraus
Fbr Data /
suhni ssion
S158.155 Nontarget Insect (CX,ntinued)
D E T G -
W l D PARASrx S:
143-1 thru 143—3 [ Beserved] 8/
1/ Oinposition: T I = l chnical Grede of the tive Ingredient; TEP = Typical End-use Product.
2/ The use patterns are coded as follows: A = i rrestrial, Fbcxl Crop; B = l rrestrial, NOn-Fbod;
C = llquatic, Food Crop; D = Aqautic, Non-Food; E = Greentxxise, Food Crop; F = Greenhouse, Non-Food;
G = Forestry; H = Danestic (xitdoor; I = Indoor
3/ Data must be s hnitted within the indicated tnus fraus, based on the date of the Guidance 1)cunent.
4/ The forestry use pattern is not included in the listing of application sites dependent upon this specific
data requiraient because the forestry application to trunks does not expose beneficial insects.
5/ As data fran aoite contact test indicate high toxicity, data on residual toxicity are required.
6/ Requiranent reserved pending develc rnent of test met1u o1ogy.
7/ Requiranent applied on a case-by-case basis. Data reviewed to date do not indicate the need for a study.
8/ Reserved pending I gency decision as to whether data requirenent should be established.
237
-------
IV. REQUIREMENT FOR SUBMISSION OF PRODUCT-SPECIFIC DATA
Note: Unless stated otherwise in Section II, Regulatory
Position and Rationale, this Section applies only to manufac-
turing—use products, not to end—use products.
A necessary first step in determining which statements
must appear on your product’s label is the completion and
submission to EPA of product-specific data* listed on the
form entitled “Product Specific Data Report” (EPA Form
8580—4, Appendix 111—1) to fill gaps identified by EPA
concerning your product. Under the authority of FIFRA sec.
3(c)(2)(B), EPA has determined that you must submit these
data to EPA in order to reregister your product(s). All of
these data must be submitted not later than six months after
you receive this guidance document.
Table B — product-Specific Data Requirements for Manufac-
turing Use Products — lists the product specific data you must
submit. Data that are required to be submitted are identified
in the column of those tables entitled “Must Data By Submitted
Under §3(c)(2)(B)”.
*/ product specific data pertain to data that support the
ormulatiOfl which is marketed; it usually includes product
chemistry data and acute toxicity data.
238
-------
TABLE B
wcr S CIFIC E 1 REOUIRFXF 1S FOR MANtJF TURING-USE Ixj ’Is rpdNI? LINIW4E
Qiideline Citation and
1 st
Oiideljnes
Are Data
Data Pt st Be
Sutinitted With
Nai
of
Test
Substance
Status
Bequired?
Yes No
Time
FraI s
Below
Listed
1/
S158.120 Product C1 anistry
Product Identity :
61-1 - Product Identity and Disclosure MP 2 / R [ ] [ ]
of Ingredients — —
61-2 - Description of Beginning Materials PIP R L i 1] 6 Pbnths
and Manifacturing Process
61-3 - Disaissicn of FOrmation of PIP R Lii] 6 ?tmths
Daintentional Ingredients 3 ! — —
Analysis ar*i Certification of Product
62-1 - Preliminary Analysis 4 ! PIP R C] 12 ?bnths
62-2 - Certification of Limits PIP R [ ] U 12 t’bnths
62-3 - Analytical Mettcds to Wrify PIP R [ j] 12 Pknths
Certified Limit — —
I4 aical a’id O nical characteristics
63-2 - (blor PIP R
63-3 - t ysical State R C i
63-4-Odor R 0 E I
239
-------
TABLE B
COCT S CIFIC TA RE UIRF 4EN S FU MANUFACI1JRING-USE WCIS X2fflAINING LINt NE
Guideline Citation and
Na of lest
1 st
Substance
()jicielines
Status
Are J)ata
i quired?
Yes NO
Data tist lie
Sutznitted With
Tine Fr S Listed
Below 1/
§158.120 Product Chanistry (Q ntinued)
rtiysical and Chauica.l Characteristics
(Ontinued)
63—7 - Density, ailk Density, or
Specific Gravity
MP
R
I ] [ x]
63—12 — pH
p
L=] [ ]
Other 1 quirunents:
64— 1 — Sukinittal of sa p1es
MP
CR
[ x l 4/ fl
MP = Manufacturir j-use Product; R = I quired; CR = Cznditionally I quired; N = Not Applicable
1/ Data must be subnitted within the indicated tinE tr ne, based on the date of the Guidance Docunent.
2/ The technical CT) also serves as a manufacturirvj—use product since lindane is not manufactured in the
United States of Nierica.
3/ The discussion must specifically address the potential for formation of dioxins and dibenzofurans.
4/ Analysis must identify and quantify all ccinponents present at greater than 0.1%, plus identification and
5/ If sanpies are rEeded the ency will request then.
240
-------
TABLE B
IXX2T S CIFIC 1 IA R UIRl 74E 1S Ft R LINIINE
Data Raquire nent
1/
Ccinposition
Use
1 ttern
I es EPA
Have Data
lb Satisfy
This
Raquiranent?
Bibliographic
Citation
?bst P idjtjona1
Data Be
Suti itted
Under FIFRA
S 3(c)(2)(B) ?
Time Frane
Fbr Data /
SuLinission
§158.135 Ibxico].ogy
wr IESrING:
81-1 - Acute Oral lbxicity - Rat
MP 3 /
All
No
Yes
9 t bnths
81—2 - Acute Dennal TOXicity
— Rabbit
NP
All
NO
Yes
9 nths
81—3 — ute Inhalation TOxicity
— Rat
MP
All
No
Yes
9 nths
81—4 - Primary Eye Irritation
1SIP
All
No
Yes
9 r.bnths
81-5 - Primary Dermal
Irritation
NP
All
No
Yes
9 Pbnths
81—6 — Dennal Sensitization
NP
All
No
Yes
9 t4 ,nths
1/ NP = Manufacturing-use Product
2/ Data must be 8 itini tted within the indicated time trane, based on the date of the jj 1 u nt
3/ The technical CT) also serves as a manufacturing-use product Since lifldafle is r t manufactured in the United
States of knerica. All formulation intermediates are inchEled in the category of manufacturing-use products.
241
-------
V. SUBMISSION OF REVISED LABELING
Note : This section applies to end-use products only to
the extent described in Section II, Regulatory Position and
Rationale. Otherwise, the following information pertains
exclusively to manufacturing—use products.
FIFRA requires each product to be labeled with accurate,
complete and sufficient instructions and precautions, reflecting
the results of data concerning the product and its ingredients.
Labeling requirements are set out in 40 CFR 162.10 (see
Appendix IV—l) and are summarized for products containing
this active ingredient as part of this Guidance Document
(See Appendix IV-2). Applications submitted in response to
this notice must include draft labeling for Agency review.
If you fail to submit revised labeling information
complying with this section (supplemented by requirements
described in Section II, Regulatory Position and Rationale),
EPA may issue a Notice of Intent to Cancel the registration
under FIFRA sec. 6(b)(l).
A. Label Contents
40 CFR 162.10 requires that certain specific labeling
statements appear at certain locations on the label. This
is referred to as format labeling . Specific label items
listed below are keyed to Appendix IV—2.
Item 1. PRODUCT NAME — The name, brand or trademark is
required to be located on the front panel, preferably centered
in the upper part of the panel. The name of a product will
not be accepted if it is false or misleading.
Item 2. COMPANY NAME AND ADDRESS - The name and address
of the registrant or distributor is required on the label.
The name and address should preferably be located at the
bottom of the front panel or at the end of the label text.
Item 3. NET CONTENTS — A net contents statement is
required on all labels or on the container of the pesticide.
The preferred location is the bottom of the front panel
immediately above the company name and address, or at the end
of the label text. The net contents must be expressed in the
largest suitable unit, e.g., “1 pound 10 ounces” rather than
“26 ounces.” In addition to English units, net contents may
be expressed in metric units. See Appendix IV—l. (40 CFR
162.10(d)]
242
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Item 4. EPA REGISTRATION NUMBER — The registration
number assigned to the pesticide product must appear on the
label, preceded by the phrase “EPA Registration No.,” or “EPA
Reg. No.” The registration number must be set in type of a
size and style similar to other print on that part ot the
label on which it appears and must run parallel to it. The
registration number and the required identifying phrase must
not appear in such a manner as to suggest or imply recommendation
or endorsement of the product by the Agency. See Appendix IV-l.
[ 40 CFR 162.10(e)]
Item 5. EPA ESTABLISHMENT NUMBER — The EPA establishment
number, preceded by the phrase “EPA Est.” is the final estab-
lishment at which the product was produced, and may appear
in any suitable location on the label or immediate container.
It must also appear on the wrapper or outside container of the
package if the EPA establishment number on the immediate con-
tainer cannot be clearly read through such wrapper or container.
See Appendix iv—l. [ 40 CFR 162.10(f)]
Item 6A. INGREDIENTS STATEMENT — An ingredients statement
is required on the front panel. The ingredients statement must
contain the name and percentage by weight of each active ingred-
ient and the total percentage by weight of all inert ingredients.
The preferred location is immediately below the product name.
The ingredients statement must run parallel with, and be clearly
distinguished from, other text on the panel. it must not be
placed in the body of other text. See Appendix IV—l. . [ 40 CFR
162.10(g)]
Item 6B. POUNDS PER GALLON STATEMENT — For liquid agricul-
tural formulations, the pounds per gallon of active ingredient
must be indicated on the label.
Item 7. FRONT LABEL PRECAUTIONARY STATEMENTS — Front panel
precautionary statements must be grouped together, preferably
within a block outline. The table below shows the minimum type
size requirements for various size labels.
Size of label Signal Word “KEEP OUT OF REACH
(front panel) (all capital letters) OF CHILDREN”
in square inches Minimum Type Size Minimum Type Size
5 and under 6 point 6 point
above 5 to 10 10 point 6 point
above 10 to 15 12 point 8 point
above 15 to 30 14 point 10 point
over 30 18 point 12 point
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Item 7A. CHILD HAZARD WARNING STATEMENT - The statement
“KEEP OUT OF REACH OF CHILDREN” must be located on the front
panel above the signal word, except where contact with children
during distribution or use is unlikely. See Appendix IV—1.
[ 40 CFR 162.l0(h)(l)(ii)]
Item 7B. SIGNAL WORD - The signal word (“DANGER”, “WARNING”,
or “CAUTION”) is required on the front panel immediately below
the child hazard warning statement. See Appendix IV—l.
[ 40 CFR 162.10 (h)(l)(i)]
Item 7C. SKULL & CROSSBONES AND WORD “POISON” - On products
assigned a toxicity Category i on the basis of oral, dermal,
or inhalation toxicity, the word “Poison” shall appear on the
label in red on a background of distinctly contrasting color and
the skull and crossbones shall appear in immediate proximity to
the word POISON. See Appendix IV—l. [ 40 CFR 162.l0(h)(l)(i)]
Item 7D. STATEMENT OF PRACTICAL TREATMENT - A statement
of practical treatment (first aid or other) shall appear on
the label of pesticide products in toxicity Categories I,
II, and III. See Appendix IV—l. [ 40 CFR 162.10(h)(1)(iiifl
Item 7E. REFERRAL STATEMENT — The statement “See Side
(or Back) Panel for Additional Precautionary Statements” is
required on the front panel for all products, unless all
required precautionary statements appear on the front panel.
See Appendix IV—l. [ 40 CFR l62.lO(h)(l)(iii)]
Item 8. SIDE/BACK PANEL PRECAUTIONARY LABELING — The
precautionary statements listed below must appear together
on the label under the heading “PRECAUTIONARY STATEMENTS.”
The preterred location is at the top of the side or back
panel preceding the directions for use, and it is preferred
that these statements be surrounded by a block outline. Each
of the three hazard warning statements must be headed by the
appropriate hazard title. See Appendix IV—l. [ 40 CFR 162.10
(h) (2)1.
Item 8A. HAZARDS TO HUMANS AND DOMESTIC ANIMALS - Where
hazard(s) exists to humans or domestic animals, precautionary
statements are required indicating the particular hazard(s), the
route(s) of exposure and the precautions to be taken to avoid
accident, injury or damage. See Appendix iv—l. [ 40 CFR 162.10
(h) (2) Ci) ]
Item 8B. ENVIRONMENTAL HAZARDS — Where a hazard exists to
non—target organisms excluding humans and domestic animals,
precautionary statements are required stating the nature of
the hazard and the appropriate precautions to avoid potential
accident, injury, or damage. See Appendix IV—1. [ 40 CFR 162.10
(h) (2) (ii)]
244
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Item 8C. PHYSICAL OR CHEMICAL HAZARDS
1. Flammability statement . Precautionary statements relating
to flammability of a product are required to appear on the
label if it meets the criteria in Appendix Iv—3. The require-
ment is based on the results of the flashpoint determinations
and flame extension tests required to be submitted for all
products. These statements are to be located in the side/back
panel precautionary statements section, preceded by the
heading “Physical/Chemical Hazards.” Note that no signal
word is used in conjunction with the flammability statements.
2. Criteria for declaration of non—flammability . The
following criteria will be used to determine if a product
is non—flammable:
a. A “non—flammable gas” is a gas (or mixture of gases)
that will not ignite when a lighted match is placed
against the open cylinder valve.
b. A “non—flammable liquid” is one having a flashpoint
greater than 350°F (177°C).
c. A “non—flammable aerosol” is one which meets the
following criteria:
i. The flame extension is zero inches;
ii. There is no flashback; and
iii. The flashpoint of the non—volatile liquid
component is greater than 350°F (177°C).
3. Declaration of non—flammability . Products which
meet the criteria for non—flammability specified
above may bear the notation “non—f lammable” or “non-
flammable (gas, liquid, etc.)” on the label. It may
appear as a substatement to the ingredients statement,
or on a back or side panel, but shall not be highlighted
or emphasized (as with an inordinately large type
size) in any way that may detract from precaution.
4. Other physical/chemical hazard statements . When
chemistry data demonstrate hazards of a physical or
chemical nature other than flammability, appropriate
statements of hazard will be prescribed. Such statements
may address hazards of explosivity, oxidizing or reducing
capability, or mixing with other substances to produce
toxic fumes.
245
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Item 9A . RESTRICTED USE CLASSIFICATION - FIFRA sec. 3(d)
requires that all pesticide formulations/uses be classified
for either general or restricted use, Products classified for
restricted use may be limited to use by certified applicators
or persons under their direct supervision (or may be subject
to other restrictions that may be imposed by regulation).
In this Registration Standard, the Agency has indicated
certain uses are to be restricted. If your product bears
any of the restricted uses, the draft label(s) submitted to
the Agency as part of your application must reflect this
determination (see below).
If you do not believe that your product should be class-
ified for restricted use, you must submit any information and
rationale with your application for reregistration. During
the Agency’s review of your application, your proposed classi-
fication determination will be evaluated in accordance with
the provisions of 40 CFR 162.11(c). You will be notified of
the Agency’s classification decision.
Classification Labeling Requirements
If this Guidance Document indicates that your product
has been classified for restricted use, the following label
requirements apply:
1. Front panel statement of restricted use classification.
a. The statement “Restricted use pesticide” must
appear at the top of the front panel of the label.
The statement must be set in type of the same
minimum size as required for human hazard signal
word (see table in 40 CFR 162.l0(h)(l)(iV)
b. Directly below this statement must appear the
cancer hazard warning as detailed in the “Labeling
Requirements for End-Use Products”.
c. Directly under the cancer hazard warning, a
summary statement of the terms of restriction must
appear :
“For retail sale to and use only by Certified
Applicators or persons under their direct supervision
and only tor those uses covered by the certitied
Applicator’s certification.”
246
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2. Some but not all uses restricted. If Section II,
the Regulatory Position and Rationale, states that some uses
are classified for restricted use, and some are unclassified,
several courses of action are available:
a. You may label the product for restricted use.
If you do so, you may include on the label uses that
are unrestricted, but you may not distinguish them
on the label as being unrestricted.
b. you may delete all restricted uses from your
label and submit draft labeling bearing only unrestricted
uses.
c. You may “split” your registration, i.e., register
two separate products with identical formulations, one
bearing only unrestricted uses, and the other bearing
restricted uses. To do so, submit two applications for
reregistration, each containing all forms and necessary
labels. Both applications should be submitted simul-
taneously. Note that the products will be assigned
separate registration numbers.
Item 9B. MISUSE STATEMENT — All products must bear the
misuse statement, “It is a violation of Federal law to use
this product in a manner inconsistent with its labeling.”
This statement appears at the beginning of the directions
for use, directly beneath the heading “Directions for Use”.
Item bA. REENTRY STATEMENT - It a reentry interval
has been established by the Agency, it must be included on
the label. Additional worker protection Statements may be
required in accordance with PR Notice 83—2, March 29, 1983.
Item lOB. STORAGE AND DISPOSAL BLOCK - All labels are
required to bear storage and disposal statements. These
statements are developed for specific containers, sizes, and
chemical content. These instructions must be grouped and
appear under the heading “Storage and Disposal” in the direc-
tions f or use. This heading must be set in the same type
sizes as required for the child hazard warning. Refer to
Appendix IV-4 to determine the pesticide and container
disposal instructions appropriate tor your products.
Item 1OC. DIRECTIONS FOR USE — Directions for use must
be stated in terms which can be easily read and understood by
the average person likely to use or to supervise the use of
the pesticide. When followed, directions must be adequate
to protect the public from fraud and from personal injury and
to prevent Unreasonable adverse effects on the environment.
See Appendix Iv—l. [ 40 CFR 162.10]
247
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B. Collateral Labeling
Bulletins, leaflets, circulars, brochures, data sheets,
flyers, or other written or graphic printed matter which is
referred to on the label or which is to accompany the product
are termed collateral labeling. Such labeling may not bear
claims or representations that differ in substance trom those
accepted in connection with registration of the proiuct.
It should be made part of the response to this Standard and
submitted for review.
248
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VI. INSTRUCTIONS FOR SUBMISSION
A. For Manufacturing—use Products (MP) containing lindane
as an active ingredient .
1. Within 90 days from receipt of this document, you must
submit to the Product Manager in the Registration Division at
the address given at the end of this section the “FIFRA Section
3(c)(2)(B) Summary Sheet” EPA Form 8580—1. Refer to Appendix
11—3 with appropriate attachments.
It on the Summary Sheet, you commit to develop the data,
request a minor chemical exemption, present arguments that a data
requirement is not applicable, or submit protocols or modified
protocols for Agency review, you must also submit a copy of the
Summary Sheet (and any supporting information) to the Office of
Compliance Monitoring, which will be monitoring the data generated
in response to this notice. This information shoulci be submitted
to the Office of Compliance Monitoring at the address given at
the end of this section. (NOTE — Actual data are not to be
submitted to the Office of Compliance Monitoring, just the items
identified above or a copy of the cover letter that accompanies
your data submission to the Product Manager in the Registration
Division.)
2. Within 6 months from receipt of this document you must
submit to the Product Manager on the Registration Division:
a. Confidential Statement of Formula, EPA Form 8570—4.
b. Product Specific Data Report, EPA Form 8580—4
(Appendix 111—1).
c. Two copies of any required product—specific data.
d. Two copies of draft labeling, including the label
and associated brochures. It current labeling contorms to
the requirements of this guidance document and the results of
the short—term data, you may submit such labeling. End—use
product labeling must comply specifically with the instructions
in Section II (Regulatory Position and Rationale) of this
Guidance Document. The labeling should be either typewritten
text on 8—1/2 x 11 inch paper or a mockup of the labeling
suitable for storage in 8-1/2 x 11 inch files. The draft
label must indicate the intended colors of the final label,
clear indication of the front panel label, and the intended
type sizes of the text.
e. Evidence of compliance with data support requirements
of FIFRA Sec. 3(c)(l)(D). Refer to 40 CFR 152.80—152.99
for latest requiremen 5
249
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3. Within the times set forth in Table A , you must submit
to the Registration DiviSiOn all generic data, unless you are
eligible for the formulator’s exemption. A copy of the cover
letter that accompanies each data submission to the Product
Manager, Registration Division, must also be submitted to the
Office of Compliance Monitoring. If, for any reason, any test
is delayed or aborted so that the agreed schedule cannot be met,
or if a change in test protocol is indicated, notify the Product
Manager, Registration Division, and the Office of Compliance
Monitoring (at the addresses given at the end of this section)
to request an extension of time or to request a change in test
protocol.
B. For Manufacturing—Use Products containing lindane in
combination with other active ingredients (other than solvents )
1. Within 90 days from receipt of this document, you must
submit the “FIFRA Section 3(c)(2)(B) Summary Sheet,” EPA Form
8580—1. Refer to Appendix 11-3 with appropriate attachments.
If on the Summary Sheet, you commit to develop the data,
request a minor chemical exemption, present arguments that a data
requirement is not applicable, or submit protocols or modified
protocols for Agency review, you must also submit a copy of the
Summary Sheet (and any supporting information) to the Office of
Compliance Monitoring, which will be monitoring the data generated
in response to this notice. This information should be submitted
to the Office of Compliance Monitoring at the address given at
the end of this section. (NOTE — Actual data are not to be
submitted to the Office of Compliance Monitoring, Just the items
identified above or a copy of the cover letter that accompanies
your data submission to the Product Manager in the Registration
Division.)
2. Within the times set forth in Table A , you must submit
to the Registration Division all generic data, unless you are
eligible for the formulator’s exemption. A copy of the cover
letter that accompanies each data submission to the product
Manager, Registration Division, must also be submitted to the
Office of Compliance Monitoring. If, for any reason, any test
is delayed or aborted so that the agreed schedule cannot be met,
or if a change in test protocol is indicated, notify the Product
Manager, Registration Division, and the Office of Compliance
Monitoring (at the addresses given at the end of this section)
to request an extension of time or to request a change in test
protocol.
250
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C. For End—Use Products (EP) containing lindane alone or
in combination with other active ingredients :
1. Within 90 days from receipt of this document:
a. If you qualify for the formulators exemption (see
PR Notice 85—3) you must submit the “Formulators Exemption
Statement”, Appendix 11—5 and a current “Confidential
Statement of Formula”, EPA Form 8570—4, to support your
request for the formulator’s exemption.
b. If you do not qualify for the formulator’s exemption
(see PR Notice 85—3) you must submit the “FIFRA Section
3(c)(2)(B) Summary Sheet,” EPA Form 8580—1, Appendix 11—3,
with appropriate attachments, and a current “Confidential
Statement of Formula”, EPA Form 8570—4.
If on the Summary Sheet, you commit to develop the
data, request a minor chemical exemption, present
arguments that a data requirement is not applicable, or
submit protocols or modified protocols for Agency review,
you must also submit a copy of the Summary Sheet (and
any supporting information) to the Office of Compliance
Monitoring, at the address given at the end of this
section, which will be monitoring the data generated in
response to this notice. (NOTE — Actual data should be
submitted only to the Product Manager in the Registration
Division)
2. Within 6 months from receipt of this document you must
submit the following items to the Product Manager in the Regis-
tration Division:
a. Five (5) copies of draft labeling, including the label
and associated brochures. If current labeling conforms to
the requirements of this guidance document and the results
of the short—term data, you may submit such labeling.
End—use product labeling must comply specifically with the
instructions in the Regulatory Position and Rationale of
this Guidance Document. Labeling should be either type-
written text on 8 1/2 x 11 inch paper or a mockup of the
labeling suitable for storage in 8 1/2 inch files. The
draft label must indicate the intended colors of the final
label, clear indication of the front panel label, and the
intended type sizes of the text.
3. Within the times set torth in Table A , you must submit
to the Registration Division all generic data , unless you are
eligible for the formulator’s exemption. A copy of the cover
letter that accompanies each data submission to the Product
Manager, Registration Division, must also be submitted to the
251
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of f ice of Compliance Monitoring. If, for any reason, any test
is delayed or aborted so that the agreed schedule cannot be met,
or it a change in test protocol is indicated, notify the Product
Manager, Registration Division, and the Office of Compliance
Monitoring (at the addresses given at the end of this section)
to request an extension of time or to request a change in test
protocol.
D. Applications and other required information should be
submitted to the following address:
George T. LaRocca
Product Manager (15)
Registration Division (TS—767C)
Office of pesticide Programs
Environmental Protection Agency
401 M St., SW.
Washington, D.C. 20460
phone No. (703) 557—2400
The address for submissions to the office of Compliance Monitoring
is:
Laboratory Data Integrity Program
Office of Compliance Monitoring (EN-342)
Environmental Protection Agency
401 M St., SW.
Washington, D.C. 20460
252
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Appendix 11-1
Guide to Use of This Bibliography
1. CONTENT OF BIBLIOGRAPHY, This bibliography contains
citations ot all studies considered relevant by EPA in
arriving at the positions and conclusions stated elsewhere
in the Standard. Primary sources for studies in this
bibliography have been the body of data submitted to EPA
and its predecessor agencies in support of past regulatory
decisions. Selections from other sources including the
published literature, in those instances where they have
been considered, will be included.
2. UNITS OF ENTRY. The unit of entry in this bibliography
is called a “study.” In the case of published materials,
this corresponds closely to an article. In the case of
unpublished materials submitted to the Agency, the Agency
has sought to identify documents at a level parallel to
the published article from within the typically larger
volumes in which they were submitted. The resulting
“studies” generally have a distinct title (or at least a
single subject), can stand alone for purposes of review,
and can be described with a conventional bibliographic
citation. The Agency has attempted also to unite basic
documents and commentaries upon them, treating them as a
single study.
3. IDENTIFICATION OF ENTRIES. The entries in this bibliography
are sorted numerically by “Master Record Identifier,” or
MRID, number. This number is unique to the citation, and
should be used at any time specific reference is required.
It is not related to the six—digit “Accession Number”
which has been used to identify volumes of submitted
studies; see paragraph 4(d)(4) below for a further explana-
tion. In a few cases, entries added to the bibliography
late in the review may be preceded by a nine—character
temporary identifier. These entries are listed after
all MRID entries. This temporary identifier number is
also to be used whenever specific reference is needed.
4. FORM OF ENTRY. In addition to the Master Record Identifier
(MRID), each entry consists of a citation containing
standard elements followed, in the case of material
submitted to EPA, by a description of the earliest known
submission. Bibliographic conventions used reflect the
standards of the American National Standards Institute
(ANSI), expanded to provide for certain special needs.
253
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Appendix 11—1 (continued)
a. Author. Whenever the Agency could confidently identify
one, the Agency has chosen to show a personal author.
When no individual was identified, the Agency has
shown an identifiable laboratory or testing facility
as author. As a last resort, the Agency has shown
the first submitter as author.
b. Document Date. When the date appears as four digits
with no question marks, the Agency took it directly
from the document. When a four—digit date is followed
by a question mark, the bibliographer deduced the
date from evidence in the document. When the date
appears as (19??), the Agency was unable to determine
or estimate the date of the document.
C. Title. In some cases, it has been necessary for
Agency bibliographers to create or enhance a document
title. Any such editorial insertions are contained
between square brackets.
d. Trailing parentheses. For studies submitted to the
Agency in the past, the trailing parentheses include
(in addition to any self—explanatory text) the fol-
lowing elements describing the earliest known submission:
(1) Submission Date. The date of the earliest known
submission appears immediately following the word
“received.”
(2) Administrative Number. The next element,
immediately following the word “under,” is the
registration number, experimental use permit
number, petition number, or other administrative
number associated with the earliest known submission.
(3) Submitter. The third element is the submitter,
following the phrase “submitted by.” When
authorship is defaulted to the submitter, this
element is omitted.
(4) Volume Identification (Accession Numbers). The
final element in the trailing parentheses
identifies the EPA Accession Number of the volume
in which the original submission of the study
appears. The six-digit accession number follows
the symbol “CDL,” standing for “Company Data
Library.” This Accession Number is in turn
followed by an alphabetic suffix which shows the
relative position of the study within the volume.
For example, within Accession Number 123456, the
first study Uld be 123456—A; the second, 123456—
B; the 26th, 1234562 and the 27th, 123456—AA.
254
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Appendix 11—2
OFFICE OF EESTICIDE GRAMS
RECISTRATION STAN [ RD BIBLIOGRAPHY
Citations Considered to be I rt of the Data Base Supporting
I gistrat ion Under the Standard F r Lindane
MRID Citation
00020560 Schafer, E.W. (1972) The acute oral toxicity of 369 pesticidal,
pharmaceutical and other ch uicals to wild birds. 1 xicology
and Applied Pharmacology 21(? ) :315—330. (Also in unpublished
sut*nission received Apr 25, 1978 under 476—2180; submitted by
Stautfer Chanical Co., RicIn nd, Calif.; CDL:233577—C)
00022923 Hill, E.F.; Heath, R.G.; Spann, J.W.; et al. (1975) Lethal Dietary
Itxicities of Envirorinental E Dllutants to Birds: Special Scien-
tific 1 port——Wi1dlite No. 191. (U.S. Dept. of the Interior,
Fish and Wildlife Service, tuxent Wildlife f search Center;
unpublished report)
00025685 Willians, S.; Mills, P.A.; McIXwefl, R.E. (1964) 1 sidues in milk
of cows fed rations containing low concentrations of five Chlo-
rinated hydrocarbon pesticides. Journal of the Association of
Official Analytical thanists 47(6):1124—1128. (Also in unpub-
lished submission received Nov 5, 1970 under 1F].060; submitted
by \ lsicol thenical Corp., Chicago, Ill,; CDL: 099195—AK)
00025690 Oi inings, J.G.; Eide]n an, M.; ¶flirner, V.; et al. (1967) I sidues
in poultry tissues fran low level feeding of five Chlorinated
hydrocarbon insecticides to hens. Journal of the Association
of Official Analytical thenists 50(2):418—425. (Also in unpub-
lished submission received Nov 5, 1970 under 1F1060; submitted
by \ lsicol Chenical Corp., Chicago, Ill.; CDL:099195— )
00025707 Hill, K.R. (1970) sticide residues: IUPAC ccmnjssion on terminal
residues. Journal of the Association of Official Analytical
thanists 53(5):987—l003. (Also in unpublished subnission re-
ceived Nov 5, 1970 under 1F1060; submitted by \ lsicol Chanical
Corp., Chicago, Ill,; CDL:099195—BH)
00031050 Feldmann, R.J.; Maibach, H.I. (1974) percutaneous penetration Of
sane pesticides and herbicides in man. lbxioology and Applied
Pharmacology 28(? ):126—]32. (Also in unp t)lished sulinission
received Apr 23, 1980 under 10279—7; siAxnitted by !klrdue Fred-
erick Co., Norwalk, Conn.; CDL:242321—R)
00032233 Dionne, E.; Cary, G sA.; Sleight, B.H., III (1980) Ana.lytiCal PrO-
cedure for the Determination of pesticides and KB in Brine
Shrimp Tiss (Unhj stt*iy received Feb 19, 1980 Under
677313; prepared by EX&G, Bioncinics, submitted by Di fld Shan—
rock gricu1t thanjcals, Cleveland, Ohio; CDL;099247—K)
255
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Appendix 11-2
(continued)
tIBID Citation
00036935 Atkins, E.L.; Grey’ mYJd, E.A.; Macdonald, R.L. (1975) Ibxicity of
r sticides and Other P ricultura1 th nicals to Honey Bees: Labo-
ratory Studies. By University of California, Dept. of EntaTolo-
gy. ?: UC, Cooperative Extension. (Leaflet 2287; published
study.)
00045126 Claborn, H.V.; Radelett, R.D.; ishland, R.C. (1960) Festicide
Residues in at and Milk: A Research Report. (U.S. ricultur—
al Research Service, Enta ology Research Div. and Animal Disease
and Ferasite Research Div., unpublished study; (DL:093429—S)
00049330 Gaines, T.B. (1969) Acute toxicity of pesticides. 1 xicology and
Applied Etiarmacology 14:515—534. (Report no. 25529; also*In
unpublished su xnission received Jul 15, 1976 under 3125—EX—135;
sutinitted by bay th nical Corp., Kansas City, £ b.; CDL:
226487—E)
00060143 Saha, J.G. (1969) Letter sent to P.E. Ferter dated Mar 10, 1969
[ Metaboli n of Lindane-14C by wheat plants]. (Caneda, Dept. of
Agriculture, Research Branch, unpublished study; CDL:091355—S)
00060150 LichteflSteifl, E.P.; Fuhraflann, T.W.; scopes, N.E.A.; et al. (1967)
Translocat ion of insecticides fran soils into pea plants: Ef-
fects ot the detergent LAS on translocat ion and plant growth.
j irnal of Agricultural and Fbcd Chanistry 15(5) :864—869. (Also
in unpublished sutznisSiOfl received Apr 5, 1969 under 9F0785;
sutini tted by Shell thanical Co., shingtCfl, D.C.; CDL:091 355—Z)
00075989 Chevron ch nica1 Canpany (1949) Milk Contanination Studies.
(Unpublished study received Jul 24, 1952 under 239—399; CDL:
231161—B)
00079816 Thorpe, E.; lker 1 A.I.T. (1973) The toxicology of dieldrin
(HEOD). I I. CanparatiVe long—term oral toxicity studies in mice
with dieldrifl, DElr, phenObarbito( [ beta]-B&iC and [ g tuia]—BHC.
Ft od and CoSfl t ics p xicolOgY 11(3): 433—442. (Also in unpub-
lished sutinissiOfl received Sep 27, 1978 under 10182—EX—li; sub-
mitted by ICI Americas, Inc., Wilmington, Del.; (DL:235600F)
00088048 GyriSco, G.G.; ptika, A.A. CanpS. (1951) RepOrt on a preliminary
Study on the Effects of Feedir 3 insecticide Treated Alfalfa Hay
to Dairy Cattle. (Unpublished study received Feb 21, 1955 under
pg)007; prepared by G.L.F. Soil .ii1diflg Service and Cornell
Univ., DeptS. of EntaW)l0 ’ , Animal HusbandrY and Dairy Indus-
try, sufxnit ted by Shell Ø tLiCal Corp., New York, N.Y •; CDL:
090081—U)
00088165 National Agricult al thanicals Association (1955?) suWl ntarY
FetitiOn for Lindafle Residue 1b1erarX e. (Unpublished study re-
ceived Jan 25, 1956 under PR)058; CDL:090056—A)
256
-------
Appendix 11-2
(Contin d)
MRID Citation
00089592 California Spray Ch uical Corporation (1959) I sidues of Lindane on
Raw Agricultural Onmodities. (Oiiçilation; unpublished study
received Apr 27, 1959 under P )190; CDL:090218—B)
00089785 t4jka, A.A.; Gyrisco, G.G., canp. (1952) Further Studies on the
Feeding of Insecticide fteated Hay to Dairy Cattle. (Unpub-
lished study received Sep 14, 1955 under PI )045; prepared by
Cornell Un, Dept. of E tc]lID1ogy and others, sutinitted by
National Agricultural th nicals Association, Falls Church, Va.;
Q)L: 090042—H)
00097842 Sanders, H.O. (1969) 1 xicity of Festicides to the Crustacean
Gamnarus iacustris. By U.S. Fish and Wildlife Service,
Fish- sticide Research Laboratory. shington, D.C.: USFVS.
(lechnical papers of the ireau of Sport Fisheries and Wildlife
25; Stauffer T —2214; published study; CDL:246020—K)
00099909 Shell Deve1o%1I nt Co. (1964) Determination of Chlorinated pesticide
Residues in Water, Soils, Craps and Animal Products: GLC-Elec-
tron Capture Metbod: Analytical Metkcd P46-43/64. (Unpublished
study received Nov 9, 1964 under unkr aknin. no.; CDL:
129668—A)
00101478 Radeleff, R. (1951) Effects of various levels of lindane in the
feed of beef cattle. ‘ terinary Medicine XLVI(3):105—106,119.
(Also in unpublished SUbe%1SS1On received Sep 14, 1955 under
Pp0045; sutxnitted by National Agricultural thanicals Assn.,
Falls Church, VA; a)L:090042—F)
00105313 ortega, P.; Hayes, W.; )urhan, W. (1957) tbologic changes in the
liver of rats after feeding low levels of various insecticides.
A.M.A. Archives of P tkx)logy 64(Dec):614—622. (Also in unpub-
lished subeassion reCeived Nov 1, 1970 under unknown achin • no.;
suP*uitted by Hercules, Inc., Agricultural th nica1s, Wilmington,
DE; Q)L:005102-K))
00104441 I ,rnstein, I.; M regor, W.; Sullivan, W. (1956) I wering the
volatility of lindane cattle sprays by addition ot tilm-torining
material. Agricultural and Fbod th nistry 4(2) :148—149. (Also
in unpublished SUbeiission received May 14, 1970 under 0H2545;
si.tznitted by Hazieton Laboratories, Inc., Falls Church, VA; Q)L:
221691—C)
00105413 Caro, J. (1969) Aca.jmilatjon by plants of orgarKx* 1orine insecti-
cides fr a n the soil. 59(9) :1191—1197. (Also
in unpublished su Zftj 5 5ion received Nov 1, 1970 under unkr n
irb iin. no.; SUtnitte d by Hercules, Inc., Agricultural thani-
CalS, Wilmington, DE;
00109141 Midb St R rican
(Biological Analysis]’ Inc. (1951) Lindane: Animal Toxicity:
ceiveci on (CC i1ation; unp t 1jg j study re-
Under unkno flo.; CDL:102026-C)
257
-------
Appendix 11—2
(Continued)
MRID Citation
00118722 National Agricultural Chemicals Assoc. (1955) [ Residues of Lin—
dane in Agricultural and Cow Products]. (Canpilation; unpub—
lished study received Jan 24, 1956 under PFOOS8; CDL:092338—A)
00118723 California Spray—Chemical Corp. (1959) [ Lindane Residues in Milk
and Meat]. (Canpilation; unpublished study received on unknown
date under PL0190; CDL:092466—A)
00118724 Collett, J.; Harrison, D. (1968) Lindane residues on pasture and
in the fat of sheep grazing pasture treated with lindane prills.
N.Z. Ji Agric. Res. 11:589—600. (Also in unpublished sutinission
received May 12, 1969 under 9E0833; sut nitted by Office of the
Catimissioner, %. shington, DC; CDL:093535—A)
00118725 National Agricultural Chemicals Assoc. (1955) The Results ot Thsts
on the Mount of Residue ! aining, Including a Description of
the Analytical Metlxxi Used: [ Lindane]. (Canpilation; unpub-
lished study received on unknown date under P O058; CDL:
098 733—A)
00118739 Chevron Chemical Co. (1949) [ BHC: Residues in Milk]. (Ccinpilation;
unpublished study received on unknown date under 239—229; CDL:
2245 48—A)
00128356 Suter, P.; Horst, K.; Luetkemeier, H. et al. (1983) 3 Months Toxi-
city Study in Rats with Lindane: 1 C Project 005220. (Unpub .-
1 ished study received May 9, 1983 under unknown admin. no.; pre-
pared by Research & Consulting Co. Ltd., Switz., suL nitted by
Zoecon Corp., E lo Alto, CA; CDL:250340—A; 250341; 250342)
00128538 sagelsdorff , p.; LutZ, W.; Schiatter, C. (1983) Covalent Binding
to MoUSS Liver DNA as Inconclusive Mechani n of Carcinogenic
Action ot Isa rs. (unpublished study
received May 9 1983 under unknown akinn. no.; prepared by
Institute ot pDxiCOlOgy, ETH, and Univ. of Zurich, Switz.,
sutinitted by ZoecOn Corp., lo Alto, CA; CDL:250339—A)
00142564 FitZhUgh, 0.; NelsOn, A.; Frawley, J. (1950) The ChroniC tOxicities
of technical benzefle hexachloride and its alpha, beta and gaTEna
jsa rS. J. E* arm. EXp. Therap. 100(1):59—66
00142715 Glatt, H. (1984) MaTlalian Cell (V79) btitagenicity lest on
Lindane: 1 kx)rt No. SP 540-VT21. lished study prepared
by Univ. of MaiflZ, Institute of xicOlOgy. 11 p.
00143513 Guenard, 3. (1984) In V VO Sister chranatid Exchange Assay in
F -p use aone .jarrow Cells with Lindafle (Intraperitoneal
Injection): Pro3ect o25716. UnpUbl35l StUdy prepared by
pesearch & Congult ing C X) • . 27 p.
258
-------
Appendix 11—2
(QDnt inued)
MRID Citation
05001991 Stevenson, J.H. (1978) The acute toxicity of unformulated
pesticides to rker honey bees (Apis n l1itera). Plant
I thology 27(1):38—40.
05002348 Burke, J.; Johnson, L. (1962) Investigations in the use of the
micro-cculanetric gas chranatograph tor pesticide residue
analysis. Journal of the Association of Official kjricultural
Chanists 45(2) :348—354.
05003005 K vacs, M.F., Jre (1966) Rapid detection of chlorinated pesticide
residues by an improved TLC technique: 3 1/4 x 4N micro slides.
Journal of the Association of Official Analytical thanists
49(2) :365—370.
05006312 Osadchuk, M.; nach, M.; McCully, K.A. (1971) Cleanup and
separation procedures for multipesticide resith analysis in
nonitoring and regulatory laboratories. Pages 357—381, in
Pasticide thenistry: Proceedings or the International IU C
Congress of Pasticide thanistry, 2nd; Feb 22—26, 1971, Tel—Aviv,
Israel. ‘ Xl. 4: Methods in I sidue Analysis. Exlited by A.S.
Tahori. New York: Cordon and Breach.
05017538 Sanders, H.0. (1972) ¶Lbxicity of Sane Insecticides to ur Species
of Malacostracan Crustaceans. Washington, D.C.: U.S. Dept.
of the Interior, Fish and Wildlife Service. (U.S. Bureau of
Sport Fisheries and Wildlife technical paper no. 66)
C 0l44O12 Johnson, W.; Finley, M. (1980) Handbook of ute 1 xicity
of Chanicals to Fish and Aquatic Invertebrates. USD1
Publication 137, Washington, D.C.
GS0315001 San Antonio, 3. (1959) Damonstration of lindane and a lindane
metabolite in plants by paper chranatography. ricultural
and Fb 1 thanistry 7(5):322—325.
GS0315002 Herbet, M.; t ber, G. (1975) Investigations on Lindane either in
Progress or Planned. Unpublished report prepared by Centre
Internatio 1 d!Ettxies du Lindane (C.I.E.L.), presented at EPA,
Washington, D.C. on Decanber 18, 1975. 17 p.
03l5003 Itokowa, H.; Schallah, A.; isgerber, I.; et al. (1970) Heitraege
zur Oekologjs thanie: X X I I. Metabo1i ijs und Rueckstandver-
halten von Lindan. .) in IlDeheren Ptlanzen. [ Contrit jtionS for
Ecological Chanistry: xjcj Metaboijan and J sicju Characteri-
iLinCj in Higher Plants ). Tetrahedron 26: 76?773.
GS0315004 thadwi R.; QDpeland, M.; Chadwick, C. (1978) &hanced pesticide
han, a Previously unreported effect of dietary fibre in
Fd. ( net. Toxiool. 16:217—225.
259
-------
Appendix 11—2
(Continued)
MRID Citation
GS0315005 Menzie, C. (1969) BHC. Pages 52—53 in Metabolism of Pesticides.
U.S. Dept. of the Interior, Bureau of Sport Fisheries and Wildlife
Special Scientific Report: Wildlife No. 127. Washington DC.
GS0315006 Menzie, C. (1974) BHC. Pages 54—56 in Metabolism of pesticides: An
update. u.s. Dept. of the Interior, Fish and Wildlife Service.
Special Scientific Report: Wildlife No. 184. Washington DC.
GS0315007 Ivey, M.; Reberts, R.; Mann, H.; et al. (1961) Lindane residues in
chickens and eggs following poultry house sprays. J. Econ.
Entaiol. 54(3):487—488.
GS0315009 Treece, R.; Ware, G. (1965) Lindane residues on alfalfa and in milk.
J. Econ. Entanol. 58(2):218—2l9.
GS0315010 Oehler, D.; Hogan, B.; Grahan, 0. (1970) Residues in milk following
treatn nt of cows with 1 indane or I nne1 to control screw- rms.
J. Econ. Entci ol. 63(5):]467—l468.
GSO315O].]. Noel, P.; Rivett, K.; Sortwsll, R.; et al. (1970) Lindane Ibxicity
Studies in Beagle t)Dgs: Initial Studies and Dietary Intake for
50 Weeks: Report No 3422/70/234. Unpublished study prepared
by Huntingdon Research Centre, Huntingdon, UK. 15 p.
GSO315012 Noel, P.; Rivett, K.; Sortwell, R.; et al. (1970) Liridane ‘Ibxicity
Studies in Beagle !rgs: Dietary Intake for 32 Weeks: Report No.
3720/70/532. Unpublished study prepared by Huntingdon Research
Centre, Huntingdon, UK. 54 p.
GSO315O].3 Rivett, K.; Sortwell, R.; Spicer, E.; et al. (1970) Lindane Itxicity
Studies in Beagle I gs: Initial Studies and Dietary Intake for
104 Weeks: Report No. 418 7/71/345. Unpublished study prepared
by Huntingdon Research Centre, Huntingdon, UK. 156 p.
GS03150].6 Ito, N.; Nagasaki, H.; Ace, H.; et al. (1975) Brief ccmlnunication:
Develo znent of hepatocellular carcinanas in rats treated with
benzene hexachioride. J. Natl. Cancer Inst. 54(3):801—805.
GS0313017 National Cancer Institute (1977) Bioassay of Lindane for tossible
Carcinogenicity. DH&J Publication No. (NIH) 77—814; Carcinogen—
esis 1 chnical Report No. 14; National Institutes of Health,
Bethesda, MD.
GS0315018 Nagasaki, H.; 1txnii, S.; Mega, T.; et al. (1977) Carcinogenicity
of Benzene Hexachioride (EHC). Pages 343—353 in Nakahara, W.,
et al, ed., “Proceedings of the 2nd International Symposiu of
the Princess Takanatsu Cancer Research Fund: 1 pics in th nical
Carcinogenesis”. University Park Press.
260
-------
Appendix 11-2
(Continued)
MRID Citation
GS0315019 Hanada, M.; Yutani, C.; Miyaji, T. (1973) Induction of hepatana in
mice by benzene hexachioride. GANN 64(5):511-513 and plate LXX.
GS0315020 KDellmer, H.; P isse, I.; Stoetzer, H. (1975) Testing of the Sub-
stance Lindane for Cancerogenic Effects in Mice Using Oral Ad-
ministration: Duration 80 eks: Celanerck Docunent No. L 139
E/75. Translation of unpublished report; original Getman text
not available. 50 p.
GS0315021 Nobuyuki, I.; Nagasaki, H.; Arai, M.; et al. (1973) Histologic and
ultrastructural studies on the hepatocarcinogenicity of benzene
hexachloride in mice. J. Nati • Cancer Inst. 51(3) :817—826.
GS0315022 to, M.; Hattori, M.; Miyagawa, T.; et al. (1972) Beitraege zur
oekologischen Ch nie: II. Hepatana—Bildung in Maeusen nach
rabreichung von HCH—Isaneren in hohen IX sen. [ Contributions
for Ecological Ch nistry: II. Hepatana deve1ogn nt in mice
after administration of HCH (EHC) isaners at high dosesi.
Chaiosphere 1(6): 279—282. With unpublished translation.
GS0315024 F lmer, A.; Lovell, M. (1971) Effect of Lindane on Pregnancy of
the Rat: Raport NO. 4307/71/463. Unpublished study prepared
by Huntingdon i search Centre, Huntingdon, UK. 36 p.
GS0315025 lmer, A.; Neutf, A. (1971) Effect of Lindane on Pregnancy of the
New Zealand %thite Rabbit: I port NO. 4308/71/464. Unpublished
study prepared by Huntingdon 1 search Centre, Huntingdon, UK.
50 p.
GS0315026 1iner, A.; Cozens, D.; LiDvell, M.; et al. (1972) Effect of Lindane
on I productive Function of Multiple Generations in the Rat:
Final 1 port: No. 4289/71/445. Unpublished study prepared
by Hufltiflgdofl 1 search Centre, Huntingdon, UK. 139 p.
GS0315031 Wilhelm, N.; Pistel, F. (1985) Metabolisn of Lindane in Rats and
Mice. Unpublished review ot published literature with attached
reprints. 25 p. attac}inent.
261
-------
(Expires 12-31.è3)
FIFRA SECTION 3(C)(2)(B) SUMMARY SHEET
EPA REGISTRATION NO.
PRODUCT NAME
APPLICANTS NAME
DATE GUIDANCE DOCUMENT ISSUED
With riupsct to ths mquirumant to a bmft Igsn.dcN u Impoad by d i . FIFRA action 3(C)(2)(B) notice contained in the referenced
Gu*d.ncs Document, I am responding in the following muinsr
01. I i.lIl aibmit dow in $ tim.iy manner to satisfy di. following requirements. If he tost procedures I will uss deviate from (or vs not
spatifiad in) the Registration Guidelines or the Protocols contained in the Reports of Expert Groups to the Chemicals Group. DECO
Chemicals Testing Progrumme, I entices the protocols that I will uas:
Attach separate par,e(s) iith a list of t ie ( 1 at 1 rw u-!reiients your corpmiv
ac ree.s to satisfy.
02. I have entered into en agreement with ons or more other registrants under FIFRA action 3(C)(2XBUii) to satisfy the following data
requirements. Tb. tests, and any required protocols, will be uibmitted to EPA by:
Attpc1 list of clat reouir ments covereri ! v a ’ ’ri nct.
NAME OF OTHER REGISTRANT
03. I enclose a completed “Certification of Attempt to Enter Into an Agreement with Other Ragistrantifor Development of Data” with
respect to th. following date requirumenoc
04. I request that you amend my reglstrvtton by diluting the following acs (this option ic not available to applicants for new products):
05. I request voluntary cancellation of di. rs 5 lwsdon of this product m,is option Is not available to applicants for new products.)
REGISTRANTS AUTHORIZED REPRESENTATIVE SIGNATURE DATE
EPA Forni $510.1 (10.12)
-------
APP iX II 4
1. I am duly
authorized to rvoruwt the following flrm(i) who
are
ibiact to the reQuire.
nisn of a
to ubmtt
NotIce wider FIFRA SectIon 3(c (2)(8) conteined in
ma cononnrnq the act v. inqredisnt
a Guidance Occuniem
MAMI O FIRM
0M8 Aooro / No. 2 O468 fFxoi,ve 1241431
CERTIFICATiON OF ATrEMPT TO ENTER
INTO AN AGREEMENT WITH OTHER REG1ST1 ANT
q afy. cerrnS’ h ur mnn’ns4
FOR DEVELOPMENT OF DATA
GUI O*NG 000UMCN1 o.* rz
(This firm or grouo at firms i ceiw ii to below at ‘mv firm”.)
2. My firm is willing to develop and au ntt the date as r.puired by that Notice. if nece ari. However, my firm would orefir to enter
Into an aqrs,m.n with one or mole other req v anu to develop jointly, or to thare in the cast of developing, the follawrng reauireC
rcat s or date:
ACTIVS INO WlIt4T
£?A CMPANY MUMMER
3. *y Inn han offered in writing to mar me much an , iemenr. Cows of the offere an suamuted. That offer an i Twacehhe and indudsd an offer to be
bound by an ar 4UaUon dsmen under FIFRA SectIon 3(c (23(B1Uii) if find a eeraent on all terms could not be iuched atherwun. This offer ye made
to die fedormi,q flrm4sl an the fdlaiearq dandal:
MAMI OF FIRM
OAT OF OFFER
iwever. none of no ffrvnlsI a osed my offer.
4. My firm requu that EPA not musoend the reqisvstIon(s) of my firm’s product(s). if any of the fIFTIIIrIlrIIOd in paragraph (3) above
have e s.d to mubmit the date listed in paragraph (2) above in acr ane widi he Not ( , EPA w fl promptly inform
me wflathsr my firm vnug sdmit date to avoid suomnelon of i reg lwadon4sl under FFRA SectIon 3(c (2)(8). (This ititimeflt
dos not apØy to aoplltenu for new producoj I give EPA permission to dusdose this mtement upon request.
rvw s*s e OATE
IP* f-- -4 4lO- 1
2 FI3
-------
Appendix Tt—
FO iUtXtV)R’ S EXEMPTION STATEMENT
(40 CFR l52. 5)
EPA File Symbol/Req. No. - —_____ Product Name ____________________
Applicant’s Name and Address __________________________________________
As an authorized representative of the applicant for registration of the
product identified above, I hereby certify that:
(1) This product contains the active ingredient(s): ________________
(2) Each active ingredient listed in paraqraph (1) is present solely
as the result of the incorporation into the product (during formulation or
packaging) of another product which..contains that active ingredient, which
is registered under FIFRA sec. 3, and which is purchased by us fran another
producer.
(3) Indicate by circling (A) or (B) below which paragraph applies:
(A) M accurate Confidential Statement of Formula (EPA Form 8570—4) for
the above identified product is attached to this statement. That formula
statement indicates, by conpany name, registration nuriber arid product
name, the source of the active ingredient(s) listed in paragraph (1).
OR
(B) The Confidential Statement of Formula dated _________ on file with
the EPA is cc*nplete, current and accurate and contains the information
required on the current CSF Form No. 8570—4. The registered source(s)
of the active ingredient(s) listed in paragraph (1) is/are listed below:
Active ingredient Source: Product nane and Reg. No .
Signature ____
Date _______________ Title ____
EPA Form (April 1985) 264
-------
Appendix 111—1
I4000Cr S €CIFIC E TA REFO1
EPA I gistratiOfl NO. ________________________ Guidance tocunent for LINDANE
Date
I gistration
Guideline
Nunber
Name of Test
Test r t
required
for my
product
listed
above
(check
below)
I an canplyi n g with
data requiranents by
(For EPA Use (Xdy)
Accession Nunbers
Assigned
Citing
MRID Nunber
or
Accession
Nunber
Sutinitting
Data
(3 Copies
attached)
S158 .20
WCT
H 4ISTRY
61—1
Identity of
Ingredients
61—2
Statanent of
Canpos it ion
61—3
Discussion of
Formation of
Ingredients
62—1
Preliminary
Analysis
62—2
Certification of
Limits
62—3
Analytical Methods
f or Enforcanent
of_Limits
63-2
Color
63—3
Physical State
63—4
Odor
63—5
Melting mint
63—6
Boiling Rint
63—7
Density, ailk—
Density, or
Specific Gravity
63—8
So]ubility
63-9
Vapor Pressure
63—10
Dissociation
Constant
63—11
Octanol/ ter
r rtiticn
Coefficient
63—12
pH
265
-------
Appendix 111—1 (continued)
EPA 1 gistration No. ________________________ Guidance lXcument for LINDANE
gistration
Guideline
Nunber
Name of Test
Test not
required
for my
product
listed
above
(check
below)
I am cauplying with
data requir nents by
(For EPA Use Only)
Accession Nunbers
Assigned
Citing
MRID Nunber
or
Accession
Nunber
Sutinitting
Data
(3 Copies
attached)
63—13
Stability
63-14
Oxidizing/Reducing
I action
63—15
F laimiabi lity
63—16
Explodability
63—17
Storage Stability
63—18
Viscosity
63—19
Miscibility
63-20
Corrosion
Characteristics
63—21
Dielectric Break—
down_\ 1tage
§158.135
loxIcX)LDGY
81—1
Acute Oral
hlbxicity_—_Rat
81—2
Acute Dermal
1 xicity
81—3
Acute inhalation,
1 Dxicity_—_Rat
81—4
Primary Eye Irri—
tation,_Rabbit
81—5
Primary Dennal
Irritation
81—6
Dermal Sensitiza—
tion
266
-------
Appendix IV—1
Oiap$.r 1—Invi ronm entol Prst.ctlon Ag.ncy
t obtained the data from anoth
f (Identify); applicant copied da
f m a pubLication: applicant ob
a py of the data froni EPA).
The applicant shall submit th
his pplicatlon a statement that A,
in I evaluation of the propertl effi-
cacy, and safety of the form ated
end- product, may not consl r any
data supporting the app tion.
except e fouowlng data:
(1) data the applicant sub-
mitted t EPA under pars, h (b) of
this secti n:
(2) Ot r data pert g to the
safety of e product’s act e Ingredi-
ents. rathe than to the ety of the
end-use pr uct; and
(3) ExIst tolerances, ood additive
regulations, xemptlo and other
clearances ed unde the Federal
Food, Drug. Cosme C Act.
Ce) If the ap licant ows that any
Item of data h sub ted under this
section was gene ted y (or at the ex-
pense of) anothe pe n who original-
ly submitted the to EPA (Or Its
predecessor. USD on or after Janu-
ary 1, 1910, to sup rt an application
for registration. xperlmental use
permit, or amen t adding a. new
use to an exist r tration, or for
reregistration ( the applicant
and the on data ubmitter have
reached writ ent on the
amount and t e terms f payment of
any compe ion that may be pay-
able und section
3(c)(1)(DR1I) with regard to approval
of the appli tion), the ap licant shall
submit to A a atateme t that he
has turnls ed to each suc identified
original submitter
(1) A a tificatlon of the a plicant’s
intent to pply for reglatratlo • includ-
ing the roposed product atm
(2) offer to pay the pens eom•
pensat a, with regard to the a royal
of th application, to the ext t re-
q by ?IPE.A sections 3(c) )(D)
and c)(2)(D);
(3 An identification of the Ite (5)
of ta to which the offer applies;
An offer to commence nego
ti to ascertain the amount d
t of compensation to be paid:
(5) The applicant’s name, addr
d telephone number.
§ 162,10
) If the applicant’s product co
t any active Ingredient other th
th that are present solely bee e
of th incorporation Into the pr ct,
dunn formulation, of one or ore
other egistered pesticide p ucts
purchas from another p ucer,
then the applicant shall comply
with 162 5 as to such ac ye ingre-
dient, and he application hall con-
tain an ac wledgment t at for pur-
poses of section 3 cXl)(D) the
application re es on ( an esult-
Ing registration should regarded as
if It were based the Mninf trator’s
consideration of) e lowing data:
(1) All data sub or specifically
cited by the appli t In support of
the registration;
(2) Each other te of data In the
Agency s files w ch:
(I) Concerns t e pro lee or effect.s
of any such ac ye Ingr at; and
(ii) Is one the types f data that
EPA would r quire to be mAtted for
scientific r ew by EPA if the appli-
cant soug t the initial r tration
under SectIon 3(c) ) of a
product th composition and tend-
ed uses dentical to those pro for
the a plicant’s product, unde the
data ulnements In effect on the
date EPA approves the appli t’s
p nt application.
(Se s. 3, 6, and 25 of F11’RA, as amended,
tJ.S.C. l3Sriasq.)
FR. 21953. May 11, 19193
I IIL1O Labeling requIrement ..
(a) Genera.l—(1) Contenls of the
labeL Every pesticide products shall
bear a label containing the informa-
tion specified by the Act and the regu-
lations in this Part. The contents of a
label must show clearly and promi-
nently the fouowinr
(I) The name, brand, on trademark
under which the product is sold as pre-
scribed In paragraph (b) of this sec-
tion;
(i i) The name and address of the
producer, registrant, or person for
whom produced as prescribed in part-
graph (a) of this section;
(ill) The net contents as prescribed
in psrsgraph (d) of this section;
27
267
-------
162.10
(lv) The product registration
number as prescribed In paragraph (e)
of this section;
(v) The producing establishment
number as prescribed in paragraph (f)
of this section;
(vi) An ingredient statement as pro-
scribed In paragraph (g) of this sec-
tion;
(vii) Warning or precautionary state-
ments as prescribed in paragraph (h)
of this section;
(viii) The directions for use as pro-
scribed in paragraph (I) of this section:
and
(Ix) The use classification(s) as pre-
scribed in paragraph (j) of this section.
(2) Prominence and legibility. (I) All
words, statements, graphic representa-
tions. designs or other Information re-
quired on the labeling by the Act or
the regulations In this part must be
clearly legible to a person with normal
vision, and must be placed with such
conspicuousness (as compared with
other words, statements, designs, or
graphic matter on the labeling) and
expressed In such terms as to render it
likely to be read and understood by
the ordinary Individual under custom-
ary conditions of purchase and use.
(I I) AU required label text must:
(A) Be set In 6-point or larger type;
(B) Appear on a clear contrasting
background; and
(C) Not be obscured or crowded.
(3) Language to be used. All required
label or labeling text shall appear In
the English language. However, the
Agency may require or the applicant
may propose additional text In other
languages as is considered necessary to
protect the public. When additional
text In another language is necessary,
all labeling requirements will be ap-
plied equally to both the English and
other-language versions of the label-
ing.
(4) Placement of Label—(i) GeneraL
The label shall appear on or be secure-
ly attached to the Immediate contain-
er of the pesticide product. For pur-
poses of this Section, and the mis-
branding provisions of the Act, “se-
curely attached” shall mean that a
label can reasonably be expected to
remain affixed during the foreseeable
conditions and period of use. If the m i-
mediate container is enclosed within a
TM. 40—Prot.cflon of £nvlronm.nt
wrapper or outside container through
which the label cannot be clearly read,
the label must also be securely at-
tached to such outside wrapper or con-
tainer, if it Is a part of the package as
customarily distributed or sold.
(ii) Tank cars and otJu r bulk con-
tafners—(A) Transportation. While a
pesticide product is in transit, the ap-
propijate provisions of 49 CFR Parts
l70-l 9, concerning the transportation
of hazardous materials, and specifical-
ly those provisions concerning the la-
beling, marking and placardlng of haz-
ardous materials and the vehicles car-
rying them, define the basic Federal
requirements. In addition, when any
registered pesticide product Is trans-
ported in a tank car, tank truck or
other mobile or portable bulk contain-
er, a copy of the accepted label must
be attached to the shipping papers,
and left with the consignee at the time
of delivery.
(B) Storage. When pesticide prod-
ucts are stored In bulk containers,
whether mobile or stationary, which
remain in the custody of the user, a
copy of the label of labeling, including
all appropriate directions for use, shall
be securely attached to the container
in the immediate vicinity of the dis-
charge control valve.
(5) False or misleading statements.
Pursuant to section 2(qX1XA) of the
Act, a pesticide or a device declared
subject to the Act pursuant to
1162.15, is misbranded if its labeling is
false or misleading In any particular
Including both pesticidal and non-pes-
ticidal claims. Examples of staLements
or representations in the labelIhg
which constitute misbranding Include:
(I) A false or misleading statement
concerning the composition of the
product:
(ii) A false or misleading statement
concerning the effectiveness of the
product as a pesticide or device:
lii) A false or misleading statement
about the value of the product forl
purposes other than as a pesticide or
device;
(iv) A false or misleading comparison
with other pesticides or devices;
(v) Any statement directly or indi-
rectly implying that the pesticide or
device is recommended or endorsed by
any agency of the Federal Govern-
ment;
(vi) The name of a pesticide which
contains two or more principal active
Ingredients If the name suggests one
or more but not all such principal
active ingredien even though the
names of the other ingredients are
stated elsewhere In the labeling;
(vii) A true statement used in such a
way as to give a false or misleading im-
pression to the purchaser:
(viii) babel disclaimers which negate
or detract from labeling statements re-
quired under the Act and these regvla-
tlons;
(I X) Claims as t.o the safety of the
pesticide or ifs ingredients, Including
statements such as “safe,” “nonpoison-
otis,” “noninjurlotis,” “hanuless” or
“nontoxic to humans and pets” with
or without, such a qualifying phrase as
‘when used as directed”; and
(x) Non-numerical and/or compara-
tive statements on the safety of the
product, including but not limited to:
(A) “Contains all natural ingredi-
ents”;
(B) “Among the least toxic chemi-
cals known”
(C) “Pollution approved”
(6) Final printed labeling, (I) Except
as provided in paragraph (a)(6X 1 1) of
this section, final printed labeling
thu,qt be submitted and accepted prior
to registration, However, final printed
labeling need not be submitted until
draft label texts have been provision-
ally accepted by the Agency.
(Ii) Clearly legible reproductions or
photo reductions will be accepted for
unusual labels such as those silk-
screened directly onto glass or metal
containers or large bag or drum labels,
Such reproductions must be of micro-
film reproduction quality,
(b) Name, brand; or trademark. (1)
The name, brand, or trademark under
which the pesticide product is sold
shall appear on the front panel of the
label.
(2) No name, brand, or trademark
may appear on the label which:
(ii Is false or misleading, or
(ii) flax not been approved by the
Administrator through registration or
supplemental registration as an addi-
tional name pursuant to 162.6(bX4),
Appendix IV—1
(continu 1 210
(C) Name and address of producer,
registrant, or person for whom pro-
duced. An unqualified name and ad-
dress given on the label shall be con-
sidered as the name and address of the
producer, If the registrant’s name ap-
pears on the label and the registrant l
not the producer, or II the name of the
person for whom the pesticide was
produced appears on the label, it must
be qualified by appropriate wording
such as “Packed for • ,“ “DIst,rlhttt.
rdby • .“or”Soldby • “t.oshow
that the name is not that of the pro.
ducer.
(d) Net weiqM or measure of eon-
lrnt.i. (I) The net weight or meLctirq’
of content, shall be exclusIve of wrap-
pers or other materials and shall be
the average content. unless explicitly
stated as a minimum quantity.
(2) If the pesticide is a liquid, the
net content statement, shah 1w in
terms of liquId measure at 68 F (2(rC)
and shall be expressed in conventional
American units of fluid ounces, pints,
quarts, and gallons.
(3) If the pesticide is solid or semiso-
lid. viscous or pressurixed, or Is a mix-
ture of liquid and solid, the net. con-
tent statement shall be in terms of
weight expres.qed as avoirdupois
pounds and ounces.
(4) In all cases, net content shall be
stated in terms of the largest suitable
units, i.e., “1 pound 10 ounces” rather
than ‘26 ounces,”
(5) In addition to the requIred iinit,q
specified, net content may be ex-
pressed In metric unIts.
(6) Variation above mInimum con-
tent or around an average Is permissi-
ble only to the extent that it repre-
sents deviation unavoidable in good
manufacturing practice. Variation
below a stated minimum Is not permit.-
ted, In no case shall the average con-
tent of the packages in a shipment Inli
below the stated average content.
(e) Product registration number.
The registration number assigned to
the pesticide product at the time of
registration shall appear on the label,
preceded by the phrase “EPA Regis-
tration No.,” or the phrase “EPA Reg.
No.” The registration number shall be
set in type of a size and style similar 1.0
other print on that part of the iahei
on which it appears and shall run par-
Chapter I—Fnvlronm.nial Protection Agency
I
2R
29
-------
16t10
allel to It. The registration number
and the required identifyhl phrase
shall not appear In auth a manner as
to suggest or hnpiy recommendation
or endorsement of-the product by the
(f) Prod*cffl9 establIshments regis-
t,utio* number. The producing istab-
lishment registration number preced-
ed by the phrase “EPA P t.”, of the
flnsJ establishment at which the prod-
uct was produced niay appear In any
suitable location on the label or Imme-
diate container. It must appear on the
wrapper or outside contaIner of the
package If the EPA establishment reg-
istration number on the immediate
container cannot be clearly read
through such wrapper or container.
(g) Ingre dient slate,ne*t—(l) Gene?-
aL The label of each pesticide product
must bear a statement which contaln 5
the name and percentaze by weight of
each active ingredient. the total per-
centage by weight of all Inert Ingredi-
ents; and If the pesticide contains ar-
senic in any form, a statement of the
percentages of total and water-soluble
arsenic calculated as elemental ar-
senic. The active ingredients must be
designated by the term “active ingredi-
ents” and the Inert Ingredients by the
term ‘inert Ingredients,” or the singu-
tar forms of these terms when appro-
priate. Both terms shall be In the
same type sire, be aligned to the same
margin and be equally prominent. The
statement “Inert Ingredients. none’ is
not required for pesticides which con-
tain 100 percent active Ingredients.
Unless the ingredient statement is a
complete analysis of the pesticide, the
tenn “analysis” shall not be used as a
heading for the Ingredient statement.
(2) PositIon of ingredient statement.
(i) The Ingredient statement is nor-
mally required on the front panel of
the label. If there Is an outside con-
tainer or wrapper through which the
ingredient statement cannot be clearly
read, the ingredient statement must
also appear on such outside container
or wrapper. If the Mae or form of the
package makes It impracticable to
place the ingredient statement on the
front panel of the label. permission
may be granted for the ingredient
statement to appear elsewhere.
7 1W. IO.—Prui.dlms .1 E,.Iaa.aI
(i i) The text of the Ingredient state-
ment must run parallel with other
text on the panel on which It appears.
and must be clearly distinguishable
from and must not be placed in the
body of other text.
(3) NameS to be used in ingredient
statement. The name used lot each in-
gredient shall be the accepted
com$flofl name, if there is one. fol-
lowm!1 by the chemical name. The
common name may be used alone only
if It Is well known. If no common name
has been established, the chemical
name alone shall be used. In no case
will the use of a trademark or propri-
etary name be permitted unless such
name has been accepted as a common
name by the Administrator under the
authority of Section 25(cXS).
(4) StatementS of percentageS. The
percentages of Ingredients shaH be
stated In terms of weight-to-weight.
The sum of percentages of the active
and the inert Ingredients shall be 100.
Percentages shall not be expre ed by
a range of values such as “22-25%.” If
the uses of the pesticide product are
expressed as weight of active ingredi-
ent per unit area, a statement of the
weight of active Ingredient per unit
volume of the pesticide formulation
shall also appear In the ingredient
statement.
(5) Accuracll of stated percentageS.
The percentages given shall be as pre-
cise as possible reflecting good manu-
facturing practice. If there may be un-
avoidable variation between manufac-
turing batches, the value stated for
each active ingredient shall be the
lowest percentage which may be pres-
ent.
(6) DeterforUtiO t. Pesticides which
change In chemical composition sig-
nificantly must meet the following la-
beling requirements:
(I) In cases where it is determined
that a pesticide formulation changes
chemical composition signIficantly.
the product must bear the following
statement in a prominent position on
the label: “Not for sale or use after
(datel.”
(ii) The product must meet all label
claims up to the expiration tIme Indi-
cated on the label.
(7) Inert Ingredients. The Adminis-
trator may require the name of any
Inert Ingredient(s) to be listed In the
ingredient statement if he determines
that such Ingredient(s) may pose a
hazard to man or the environment.
(h) Warnings and precautionary
stu1e,nents Required warnings and
precautionary statements concerning
the general areas of toxicological
hazard including hazard to children,
environmental hazard, and physical or
chemical hazard fall Into two groups;
those required on the front panel of
the labeling and those which may
tip lv d 50
t*, So m d So i, 2
tip iv . no
C—
I0I . -v.*l ’
,.45* 7 r’
S r . I Co,vodi.
(I) Human hazard .ifqnal uiord—(A)
Toxicity Category I. All pesticide prod-
ucts meeting the criteria of Toxicity
Category I shall bear on the front
panel the signal word “Danger.” In ad-
dition If the product was assigned to
Toxicity Category I on the basis of Its
oral, inhalatIon or dermal toxicity (as
distinct from skin and eye local ef-
fects) the word “Poison” shall appear
in red on a background of distinctly
contrasting color and the skull and
crossbones shall appear in immediate
proximity to the word “poison.”
(B) Toxicity Category II. All pesti-
cide products meeting the criteria of
Toxicity Category II shall bear on the
front. panel the signal word “Warn-
ing...
(C) Toxicity Category Ill. All pesti-
cide products meeting the criteria of
Toxicity Category III shall bear on
the front panel the signal word “Cau-
tion.”
(U) Toxicity Cat.’ qory IV. All pesti-
cide products meeting the criteria of
Toxicity Category IV shall bear on the
front, panel the signal word “Caution.”
(E) Use of signal words. Use of any
signal word(s) n.csociated with a higher
§ 162.10
appear elsewhere. Specific require-
ments concerning content. placement,
type size, and prominence are given
below.
(I) Required front panel stefrments,
With the exception of the child
hazard warning statement. (-he text. re-
quired on the front panel of the iatwi
is determined by the Toxicity (‘ittego-
ry of the pesticide. The category is as-
signed on the basis of the highest
hazard shown by any of the indicators
in the table below:
N
moo liv mom 50 i ni. u ’. 1 0.. qmm 501
I i , ,
F.m. 2. liv 20 mqlliw.i fl.m , * ,, 70 n I
No co,nm °m r.
- --- . 7_.
M d...$ , bem.*,.. 72 ta.i ‘ Soliaw, ml
,loua I 7 iwi .is
Toxicity Category is not permitted
except when the Agency determines
that such labeling is necessa ry to pre-
vent unreasonable adverse effects on
man or the environment. In no ease
shall more than one human hszard
signal word appear on the front panel
of a label.
(ii) Child hazard warning. F very pes-
ticide product label shall bear on (lie
front panel the statement “keep out. of
reach of children.” Only In eases
where the likelihood of contact, with
children during distribution, market-
ing, storage or use Is demonstrated by
the applicant to be extremely remote.
or if the nature of the pesticide is such
that it Is approved for use on infants
or small children, may the Adniinistra-
tot waive this requirement.
(iii) Statement of practical 1 ,-cot-
inent—(A) Toxicity Category I. A
statement of practical treatment. (first
aid or other) shall appear on 1.1w front
panel of the label of all pesticides fail.
ing into Toxicity Category I on 1. 1w
basis of oral, Inhalation or dermai tox-
icity, The Agency may, however,
permIt reasonable variations in the
placement of the statement of pr.’tcli
Prot,dlon Agency
Appendix IV—1
(continued)
Nozwd
O.mlLO,.
bJ%J . .U , . . , LC.,.
Dm,.d to,.
F yi illici,
I .- .-- ---
mo moo iipflq
F.oo . .2 liv 2 1 1 1 5 1 1 1 W
200 liv 2000 Ft ii 2.000 liv 20.000. ‘ ‘ 70.0 ( X)
v 7
— fr So*
7 dsym.
5mm.. SolImlon ii 72
30
-------
§ 162.10
cal treatment is sonte reference such
as “See statement of prs.cUcal treat-
me’nt on back panel’ appears on the
front panel near the word “Poison”
and the skull and crossbones.
(B) Other toxfcUg categories. The
statement of practical treatment Is not
required on the front panel except as
described in paragraph (h)(lXillXA) of
this section. The applicant may. how-
ever, include such a front panel state-
ment at his option. Statements of
practical treatment are, however, re-
quired elsewhere on the label in
accord with paragraph (hX2) of this
section if they do not appear on the
front panel.
(iv) Placement and prominence. All
the require front panel warning state-
ments shall be grouped together on
the label, and shall appear with suffi-
cient prominence relative to other
front panel text and graphic material
to make them unlikely to be over-
looked under customary conditions of
purchase and use. The following table
shows the minimum type size require-
ments for the front panel warning
statements on various sizes of labels:
r I .__ L __ (Wi sd
Iwo’ l tJ. Do not biosSi, wc ’ t isI o’
,.*t). Do not 5ot kt spss, *i, o’ on iq
tr punot 4J ..id ci , , .iJ . lsa n,, ,4 is-
—-‘-
us, b istot I . . . t. __ J Ikdci.d o’
I I. st eJ. Do not bush. v o’. t .ist o’
w’ .v ndsI). Do — ‘ pss. on sk o’ on
doh*iq ( 5 U . hot slpL. .4 . rwp*.d.).
I In* I . —1. _ J Iwshsd o’ UL..,.I%. .4 hv ,iulh I .
ot k J. Avdd shiIi Y o’i 1htst o’ s, Iot IJ.
Ascot cocisci cia ota is,.. ot ’ i. t ps-
pd.I. Sot .ot £ .L.. _ J us h—d.t .
INc csuUoi.. otj...,. ..j . , *.di
(ii) Environmental hazards. Where a
hazard exists to non target organisms
excluding humans and domestic ani-
mals, precautionary statements are re-
quired stating the nature of the
hazard and the appropriate precau-
tions to avoid potent .IaJ accident,
Sb. ci st bout — fri .o’.
,-.--
fl. *.d “Sssp cot
— oiisuchoi
ch l&.n
Ssndunduw
MiousSlotO
Abou1O l5
AbosctSIo SO
o ’,lo - -
e
to
12
14
IS
•
I
5
tO
12
(2) Other required warnings and pre-
cautionary statements. The warnings
and precautionary statements as re-
quired below shall appear together on
the label under the general heading
Precautionary Statements” and
under appropriate subheadings of
“Hazard to Humans and Domestic Ani-
mals.” “Environmental Hazard” and
“Physical or Chemical Hazard”
(I) Hazard to humans and domestic
animals, (A) Where a hazard exists to
humans or domestic animals, precau-
tionary statements are required mdi-
cating the particular hazard, the
route(s) of exposure and the precau-
tions to be taken to avoid accident.
injury or damage. The precautionary
paragraph shall be immediately pre-
ceded by the appropriate hazard signal
word,
(B) The following table depicts typi-
cal precautionary statements. These
statements must be modified or ex-
panded to reflect specific hazards,
Con otos, causes .p. — ibbi dwuusqs to’ sloit
frdlshonl Do not sI kt syss. Oil sbfri, ci On
doP*i . Ws gogçhi. ci (so. stdstd si’4 nMi
qIoes. idlon t ,, 5., . Husmlu ci lu st P
SM td . 4,J .,, . ..—,l r,qi*sd I
.iiss. sy. I.nd MiMI frdtstluut Do nd put fri syss.
cii sbfrt, ci on doU* HwmI I . .5,,.. ..J . tAp-
5. 1 M d . .t.J.,,.,. ., .t ieup*sd l
Avoid cootsc* sib sliM, eyes ci deI* . hi cse. ci
Onnisci fr0 ...$J.t.I SiMs eyes ci hiM sills pisudy ci
sSls,. Out Millet . .fl. ,,.U ,,, . P hiI.Ion psushite.
IN c ecs’ nsuy . I _ .-,j . rsup*sidl
injury or damage. Examples of the
hazard statements and the circum-
stances under which they are required
follow:
(A) If a pesticide intended for out-
door use contains an active ingredient
with a mammalian acute oral I D. of
100 or less, the statement ‘This Pesti-
cide is Toxic to Wildlife” is required.
(B) If a pesticide Intended for out-
door use contains an active lngredieni,
with a fish acute LC.. of I ppm or les,s,
(he statement “This P stIcidp is Toxic
to Fish” is required.
(C) If a pesticide intended for out-
door use contains an active ingredient
with an avian acute oral LD,.. of 11)0
mg/kg or less, or a subartite dietary
LC,. of 500 ppm or less, the statement
“This Pesticide is Toxic to Wildlife” is
required.
(D) If either accident history or fIeld
stndI s demonstraf,e that use of the
pesticide may result in fatality to
birds, fish or mammals, the statement.
(I) Directions for lJse—(l) General
requjrem,nts_(I) Adequacy and cZar-
itv of directions. Directions for use
must be stated in terms which can be
easily read and understood by the
average person likely to use or to su-
pervise the use of the pesticide, When
followed, directions must be adequate
to protect the public fron fraud and
from personal injury and to prevent
unrea.qonable adverse effects on the
environment
(ii) Placement of directions for use.
Directions may appear on any portion
of the label provided that they are
conspicuous enough to be easily read
by the user of the pesticide product,
Directions for use may appear on
printed or graphic matter which ac-
companies the pesticide provided that:
§ 162,10
“This pesticide is extremely toxic to
wildlife (fish)” is required.
(E) For uses involving foliar applica-
tion to agricultural crops, Int-r’sic, or
shade trees, or for mosquito shale-
ment. treatments, pesticides inxic to
pollinating insects must hear alipropri.
ate label cautions.
(F) For all outdoor Uses other hiatt
aquatic applications the laheJ lutist.
hear the caution “Keep out of l k s,
ponds or streams. Do not cont minaIr
water by cleaning of equilpnu’jil or dis-
posal of wastes”
(iii) Phtjsjcaj or eheynfral hn.’ rd
Warning statements on the flamnutbji-
ity or explosive cttaracterisiles or the
pesticide are required as roliows-
fl SOi* i ld
(A) If required by the Agency, such
printed or graphic matter is sertirr’iy
attached to each package of the pesti-
cide, or placed within the out.sid
wrapper or bag;
(H) The label bears a refere,ice to
the directions for use in accompanying
leaflets or circulars, such as “See di-
rections in the enclosed circular” and
(C) The Administrator determines
that it is not necessary for such direc-
tions to appear on the label.
(iii) Exceptions to requlremi’yut for
direction for use—(A) Detailed direc-
tions for use may be omitted from la-
beling of pesticides which are int.rnded
for use only by manufac(,tirers of prod-
ucts other than pesticide products in
their regular manufacturing processes,
provided that:
Tilt. 4 O—Prot.ctIon of Envh’onm.nl
Chupf.r I—fnvlron,n .snto( Protection Agency
Appendix IV—1
( ontfnued)
Pnicsuion.uy . I-s —.l . by So Sy
bdiJ. .& ci — Io*hy Silo ass eye (scsi .il.c$s
To*IIy
‘ . 1 1 0 , — I
N
N
(A) Pnc,’n,n.nn Cootosicn,
issh polo) . 5 ci bulow 20’ F; N Ny. K a NsiMbs ,,t , . F , ’i,novd Nsownh9 Conivoli jw . , is. Km” 0 iwsy I,o,n
any oslo. opun(ng thu. o scki, sod h.*Ind qisfuemi On not pon 1,..’
conisSnu. Fn oq..o , ten,p.,sfr,mq ifrflv,, 1 )0 r nisy
his.iin
Flails polot sisoy, 20’ F and not two’ 00’ F • , IKe Flanwoubi. Coot’,), undo’ vmqq .m K.n ’p sway lion, 5,-ui.
Oso.. nitunilon Is mci. Ow , ii hi long s 5 a iiMtsncw Ws.kq. sod no” , s.n. Do ocS pooch.,., oh -to , 55 m l , , - , -,
oi l lii lion. 1K., flan,s. Espow .. . lo t o’° ! s ’J’., sb 0 .. 110 F mnqy c’,,,
Al nib, p,mqwlp.d Co,WsIn . , - - - Con$uw,t. isnis, )weoo . ,, On not uoa ci ito,.. n .s, Iw,si is
Ian,. Do not psaict ,,. iv hiclnumsi . ennishi.,, F iy,
Imnywwstu,*q *isov. t )0 F m.y Cs.iq h qHo 0
(5) Nowpnyqs ,,n,,yr, CCwyow .cnq
At ci below 20’ F - - - F køn &p ltwn,n.,t,l. K ’ , 5 , ass, from 5 m ‘psik’.. sod h. .sI..d
stab,’,
Abow. 20’ F sod _ eo F Fi.inwn .bl, Kisuç . awsy from hess sod ot,- . , Miwo,
Abo,,. 1)0’ I’ sod is,) ova I SO’ I Do flfl 5 U’.. ci itO .., flea h ’ ,I 0 (5)00 Osmo
-------
§ etiO
(1) The label clearly shows that the
product is Intended for use only in
manufactuling p .oc Me5 and specifies
the type(s) of products involved.
(2) Adequate infonn*t.iOfl such as
technical data sheets or bulletins. is
available to the trade spedfylng the
type of product Involved and its
proper use In manufacturing process-
ex
(3) The product wUl not conic into
the hands of the general public except
after incorporaUofl Into finished prod-
ucts; and
(4) The Adminletrotor determines
that such directions are not necessary
to prevent unreasonable adverse ef-
fects on man or the environment.
(B) Detailed directions for use may
be omitted from the labeling of perU-
chic products for which sale Is limited
to physicians. veterinarians. or drug-
gists. provided that:
(1) The label clearly states that the
product Is for use only by physicians
or veternaria
(2) The Admiflhltilitor determines
that such direcUons are not necessary
to prevent unreasonable adverse ef-
fects on man or the environment and
(3) The product is also a drug and
regulated under the provisions of the
Federal Food. Drug and Cosmetic Act.
(C) Detailed directions for use may
be omitted from the labeling of pesti-
cide products which are intended for
use only by formulators in preparini
pesticides for sale to the public, pro-
vided that:
(I) There is Information readily
available to the formulators Ofl the
composition, toxicity, methods of use.
ppllcable restrictions or limitations.
and effectiveness of the product for
pesticide purposes
(2) The label clearly states that the
product Is intended for use only In
anufacturIflg. formulating, mixing,
or repacking for use as a pestlctdc and
specifies the type(s) of pesticide prod-
ucts involved;
(3) The product as finally manufac-
tured, formulated, mixed, or repack-
aged is regiMere(l nd
(4) The Administrator determlfl’I’
that such directions are not necessary
to prevent unreasonable adverse rf-
fecta on man or the environment.
TiiI . 4O -’P,ot.dI.1 .f nvkonMSlIi
(2) Co*tefltS of Directions for Use.
The directions for use hali include
the following, under the headings “Di-
rections for Use”:
(I) The statement of use cl sslflc*-
tion as prescribed In 1 62.10(J) immedi-
ately under the heading ‘Directions
for Use.”
(ji) Immediately below the state-
mept of use classificatIOn, the state-
ment “It is a viol tiofl of Federal law
to use this product In a manner Incon-
sistent with Its labeling.”
(lii) The site(s) of application, as for
example the crops. animals, areas, n t
objects to be treated.
(lv) The target pest(s) associated
with each site.
(v) The dosage rate associated with
each site and pest.
(vi) The method of application. In-
cluding instructions for dilution, if to-
quired, and type(s) of application ap-
paratus or equipment required.
(vii) The frequencY and timing of ap-
plicationS necessary to obtain effective
results without causing unreasonable
adverse effects on the environment.
(viii) Specific limitations on reentry
to areas where the pesticide has been
applied, meeting the requirements
concerning reentry provided by 40
CFR Part I’fO.
(Ix) Specific directions concerning
the storage and disposal of the pesti-
cide and Its container, meeting the re-
quirements of 40 CFR Fart 165. These
instructions h ll be grouped and
appear under the heading “Storage
and DispOsal.” This heading must be
set in type of the same minimum siv.es
as required for the child hazard lam
ing (See Table m l 162.l0(hXlXiV).)
(x) Any limitations or restrictions on
use required to prevent unreasonable
adverse effects, such as:
(A) Required Intervals between ap-
plicaUOfl and harvest of food or feed
crops.
(B) Rotational crop restrictions.
(C) Warnings as required against use
on certain crops, animals, objects, or
In or adjacent to certain areas.
(D) tR tierved)
(F.) For restricted use pe LlcIde . a
statement that the pesticide may be
5 ppiled under the direct supervision of
a certified applicator who is not phys-
ically present at the site of application
Chapter i—EnvI,
but nonetheless available to the
person applying the pesticide, unless
the Agency has determined that the
pesticide may only be applied under
the direct supervision of a certified ap-
plicator who Is physIcally present.
(F) Other pertinent. Information
which the Administrator determines
to be necessary for the protection of
man and the environment.
(J) Statement of Use Classtfication.
By October 22. 1976. all pesticide prod-
uc La must bear on their labels a state-
ment of use cla.csiflcation as described
In paragraphs (j)(l) and (2) of this sec-
tion. Any pesticide product for which
some uses are classified for general ise
and others for restricted use shall be
separately labeled according to the la-
beling standards set forth In this sub-
sectIon, and shall be marketed as sepa-
rate producis with different registra-
tion numbers, one bearing directions
only for general use(s) and the other
bearing directions for restricted use(s)
except that, If a product has both re-
stricted lace(s) and general use(s), both
of these uses may appear on a product
labeled for restricted use. Such prod-
ucLa shall be subject to the provisions
of 3 162.iO(JX2).
(1) General rise Class ificalion. PerU-
dde products bearing directions for
vise(s) classifIed general shall be la-
beled with the exact words “General
Classification” immediately below the
heading “Directions for Use.” And ref-
erence to the general classification
that suggests or Implies that the gen-
eral utility of the pesticide extends
beyond those purposes and vases con-
tained In the D lrpctlon.s for Use will be
considered a false or misleading state-
ment under the statutory definitions
of misbranding.
(2) Restricted Use Classification,
PextIcid products bearing direction
for vise(s) classified restricted shall
bear statements of restricted use clas-
sification on the front panel as de-
scribed below
(I) Front panel statement of restrict-
ed vise classificatfpn (A) At. the top of
the front panel of the l*bel, set. In type
of the same minimum sizes as required
for hvima,i haz.ard signal words (ace
table in 3 l02.lO(h)(l)(iv)) and appear-
Ing with anflictent promtnpncp relative
to other text and graphic material on
Appendix IV—!
(cont inued)
Agency § 162.11
the front panel to make It. unlikely to
be overionked under customary condi-
tions of purchase and use. the slate
ment “Restricted Use PestIcide” shall
appear.
(H) Directly below this statement. on
the front. panel, a summary statement.
of the terms of restriction ifnpoSe(1 as
a precondition t.o registration shall
appear. If use is restricted to certified
applicators, the lollowing st.atrvn nt. Is
reqvilred: “For retail snle 1.0 avid use
only by Certified Applicators or per-
sons under their direct. supervision nnd
only for those uses covered by t.tuc Cer.
Lit led Applicator’s c.ert,i Iirat.lon ” If,
however, other regulatory rcsl.riel.ions
are imposed, the Administ,rni.or will
define (he appropriat.c wording for the
terms of restrict-ion by regulation.
(k) Advertising. (Reserved)
(40 FR 25250, July 3. 1075: 40 FR 32 120,
Aug. 1. lO IS 40 FR 30511. Aug. 21. 1075, AS
*mended at 43 FR 5705, Fi’b. 1), 10101
P 2.11 (rlteris for dctermlnuitionq or ii -
q-aqon t,l ad , ,,-.. ,ffcrt .
(a) rtteria for Issuance of Noii r of
mien to Deny Registration, (ancel
Regist lion, or to hold a lie ring
(I) Pres mption. (I) A rebut,t. )le pt-c-
sumpt ,lo shall arise that, a ollee of
intent to ny registration p rsuinnt. to
section 3(c 6) of the Act, notice of
intent to Ca cei rrgisl.rat n pursuiatit.
to section 6 MI) of I, e Act., or a
notice of inte to hol a hearing to
determine wh her e registration
should be cance ed r denIed, as ap-
propriate, shall sued, upon a de-
termination by the dminist.rator that
the pesticide mee r exceeds any of
the criteria for ak . t forth in para-
graph (aX3) of Is se Ion. Upon such
determination the Administrator
shall ls ue n ice by cc ,Ified mail t.o
the applies or regist.ra , as U n ’ case
may be, t ing that the pltcant, or
registrant has the oppo unity to
submit tdence In rehuitta of such
presum ion in accordance w I i ,nra
graph )(4) of this section. ‘1’ appli-
cant registrant shall have fo v five
(45) ays from the date such no (-e is
sen to submit evidence In rebuilt of
th presumption: provided. howe ‘r,
t at for good cause shown the Adin i
trator may grant an additional sist
35
., a
-------
APPENDIX IV—2
LABELING Rg UIRENENrs Oi ThE FIFRA, AS AMENDED
IT 1
lABEL ELE2iEN
APM.ICABILITY
OF REQ(JIRENENT
PLACE}IENT CtJ LABEL
-
1
Product nai
All products
Front panel
EFERRED
Center tront
panel
Q]’*iFNrS
2
Ca pany name
and address
All products
None
Bottan front
panel or end
of label
it registrant is rxt the producer, must
be qualified by “ cked for . .
3
Net contents
All products
None
text
Bottan front
panel or end
NDjstriboted by. . .,“ etc.
May be in metric units in addition to
U • S • units
4
EPA 1 g. No.
All products
None
of_label_text
Front panel
Must be in similar type size and run
5
EPA Est. No.
All products
None
Front panel,
initediately
before or
following
No.
parallel to other type.
May appear on the container instead of
the label.
6A
Ingredients
statement
All products
Front panel
i g.
Inirudiately
following
Text must run parallel with other text
on the panel.
6B
Rxinds/gallon
statement
Liquid products
where dosage
given as lbs.
ai/unit area
Front panel
product_name
Directly below
the main
ingredients
statement
7
Front panel
precautionary
statements
All products
Front panel
All front panel precautionary statements
must be gr .rped together, preferably
7A
Keep (‘it of 1 ach
of thildren
(thud hazard
warning)
All products
Front panel
Above signal
rd
blocked.
Note type size requirements.
7B
Signal rd
All products
Front panel
Inimediately
below child
hazard
warning
Note type size requirements.
272
-------
APPENDIX IV-2 (continued)
IT 74
LABEL EL.E74EN]
APPLICABI LIT!
OF REQUIR 1iENT
PLACF}IENT (X4 LABEL
t lENI S
REQUIRED
1 EFERRED
7C
Skull & cross—
bones ard rd
EOISCt (in red)
All products
which are Cat—
egory I based
on oral, der—
mal, or inhala-
tion toxicity
Front panel
Both
proximity to
signal rd
7D
Stat nt of
practical
treath*nt
All products
in Categories
I, II, aril iii
Category I:
Front panel
unless refer-
ral stat nent
is used.
Others:
Grouped with
side panel
precautionary
statanents.
Front panel
for all.
7E
Referral
statw nt
All products
where pre-
cautionary
labeling
appears on
other than
front panel.
Front panel
side
Must be grouped under the headings in
8
Side/back panel
precautionary
statanents
All products
None
l p or
of back panel
preceding
direct ions
f or use
above
8A, 8B, and 8C; preferably blocked.
Must be preceded by appropriate signal
8A
Hazards to
hunans and
danestic
animals
All products
in Categories
I, II, and III
None
Sane
above
rd.
Envirorinental hazards include bee
8B
Envirorinental
hazards
All products
None
Sane as
caution where applicable.
273
-------
AP NDIX IV-2 (continued)
ITE
LABEL EL.E2IEVT
APMJCABILITY I PLAC l ’r ON LABEL I
OF RF)QUIRF2’IENr REQUIRED
8C
1hysical or
chQnical
hazards
All pressurized
products, others
with flash points
under 150°F
None
EFERRED
sane as above
(X14MEN S
9A
Restricted
block
All restricted
products
Tbp center
of front
panel
Preferab1y
blocked
Includes a stat uent of the terms of
restrict ion. The words HI I ( J) USE
PESTICID€” must be same type size as
signal word.
9B
Misuse
stat nent
All products
Im mediately
following
heading of
Directions
for_Use
“It is a violation of Federal law to use
this product in a nanner inconsistent
its labeling.”
1OA
Re-entry
stat nent
See Notices
83—2 and 84—1
In the
directions
f or use
I m mnediately
after misuse
stat nent
lOB
Storaje and
disposal block
All products
In the
directions
for use
lirnEdiately
before
specific
directions for
use or at
the end of the
directions
for_use
Must be set apart and clearly distin—
guishabie frciii fran other directions
for use.
lOC
Directions
for_use
All products
None
None
May be in metric as ll as U.S. units
274
-------
PRECAUTIONARY STATEMENTS CROP:
HAZARDS TO HUMAN$ I
* DOMESTIC AIlI ALS ___
- CAUTION ____
ENVmONUENTAI. HAZARDS
_____ PRODUCT
PHYSICAL OR CHEMICAL
___________________ ACTWE R GREDENT: _____________ S
NEAT PIGREDIENTS: ____________ S =
• • - --‘ d F. SP buw b use TOTAL
*M pm i $ IW b .i4
CROP:
REENTRY STATEMENT THIS PRODUCT CONTAIlS LBS OF PER GALLON
— ‘ A,I 4 ’j
_____________ KEEP OUT OF REACH OF CHILDREN —
___ ___ CAUTION _
- ____ STATEMENT OF PRAC11ÔAL REAT14ENT STORAGE AND
____ F SWALLOWED_____________________ DISPOSAL
_______ F PIHALED_______________________________ STORAGE __________
_______ VON 8 1 ( 54
— : ____ VI4EYE$ ____________
SEE S OS PANEL FOR ACOmONAI. PRECAUTIONARY STATEMENTS
MFG BY_________________ WARRANTY STATEMENT
TOWN. STATE______________
ESTABUSHMENT NO. ___________
EPA REGiSTRATION NO. -
NET CONTENT S
? 75
-------
CROP:
PRECAUTIONARY STATEMENTS
HAZARDS TO HUMANS
(1 DOMESTIC ANIMALS)
DANGER
I Fsdsr bw b us
1* b S MWV V Is s
‘Iu II. bs*iQ.
REEN1BY STATEMENT
(P ApçIc Is)
PRODUCT
NAME
ACT WE P OREDIENT:
PIERT P4OREDIENT$:
S
TOTAL: 100.00%
ThIS PRODUCT CONTAUIS LBS OF PER GALLON
KEEP OUT OF REACH OF CHILDREN
DANGER —I
SEE SCE PANEL FOR ADOmONAI. PRECAUTIONARY STATEMENTS
MFG BY.
TOWN. 1
ESTABUSHMENT NO. ____________
EPA REGISTRATiON NO. __________
NET CONTENTS
ENVIRONMENTAl. HAZARDS
RESTRICTED USE
PESTICIDE
(reason for c1as ifytn )
R AX SA Z Al D LEE ILY BY CERTtrico APPUCA1 OR
ORS UN ThEIR DI .T SUPERVISIC AND QILY . TI SE
W VE1 D BY ThE CERrIFIED APPLICA1VR’s CERTIFICA j( I
PHYSICAL OR CHEMICAl.
HAZARDS
DIRECTIONS FOR USE
STORAGE AND
DISPOSAL
STATEMENT OF PRACTICAl. TREATMENT
F
F —-
F ON SKt4
F W I EYES
CROP:
276
-------
Appendix IV—3
PHYSICAL-CHEMICAL HAZARDS
Criteria
Required Label Statement
I. Pressurized Containers
A. Flashpoint at or below
20°F; or if there is a
flashback at any valve
opening.
B. Flashpoint above 20°F
and not over 80°F; or
if the flame extension
is more than 18 inches
long at a distance ot
6 inches from the
valve opening.
C. ALL OTHER PRESSURIZED
CONTAINERS
II. Non—Pressurized Containers
Extremely flammable.
Contents under pressure.
Keep away from fire, sparks,
and heated surfaces.
Do not puncture or incinerate
container. Exposure to
temperatures above 130°F
may cause bursting.
Flammable. Contents under
pressure. Keep away from
heat, sparks, and flame.
Do not puncture or incinerate
container. Exposure to
temperatures above 130°F
may cause bursting.
Contents under pressure.
Do not use or store near
heat or open flame.
Do not puncture or incinerate
container. Exposure to
temperatures above 130°F
may cause bursting.
A. Flashpoint at or below
20°F.
B. Flashpoint above 20°F
and not over 80°F.
C. Flashpoint over 80°F
and not over 150°F.
D. Flashpoint above
150° F.
Extremely flammable.
Keep away from fire, sparks,
and heated surfaces.
Flammable. Keep away from
heat and open flame.
Do not use or store near
heat and open flame.
(None required
277
-------
Appendix IV—4
STORAGE AND DISPOSAL INSTRUCTIONS FOR PESTICIDES
All products are required to bear specific label instructions
about storage and disposal. Storage and disposal instructions
must be grouped together in the directions for use portion of
the label under the heading STORAGE AND DISPOSAL. Products
intended solely for domestic use need not include the heading
“STORAGE AND DISPOSAL.” The STORAGE AND DISPOSAL heading
must appear in the minimum type size listed below:
Required type size
Size of label
for the heading
front panel in
STORAGE AND DISPOSAL
square inches
(all capitals)
10 and under .
Above 10 to 15
Above 15 to 30
Over 30. . . .
.
.
.
.
.
.
.
.
.
.
•
.
.
.
.
.
.
•
.
•
.
•
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
.
. . . .6 point
. . . .8 point
. . . 10 point
. . . 12 point
Storage and disposal instructions must be set apart and
clearly distinguishable from other directions for use.
Blocking storage and disposal statements with a solid line is
suggested as a means of increasing their prominence.
A. Storage Instructions :
All product labels are required to have appropriate storage
instructions. Specific storage instructions are not prescribed.
Each registrant must develop his Own storage instructions,
considering, when applicable, the following factors:
1. Conditions of storage that might alter the composition or
usefulness of the pesticide. Examples could be temperature
extremes, excessive moisture or humidity, heat, sunlight,
friction, or contaminating substances or media,
2. Physical requirements of storage which might adversely
affect the container of the product and its ability to
continue to function properly. Requirements might include
positioning of the container in storage, storage or damage
due to stacking, penetration of moisture, and ability to
withstand shock or friction.
3. Specifications for handling the pesticide container,
including movement of container within the storage area,
proper opening and closing procedures (particularly for
opened containers), and measures to minimize exposure
while opening or closing container.
278
-------
Appendix IV—4
(continued)
4. Instructions on what to do if the container is damaged in
any way, or if the pesticide is leaking or has been spilled,
and precautions to minimize exposure if damage occurs.
5. General precautions concerning locked storage, storage in
original container only, and separation ot pesticides
during storage to prevent cross—contamination of other
pesticides, fertilizer, food, and feed.
6. General storage instructions for household products should
emphasize storage in original container and placement in
locked storage areas.
B. pesticide Disposal Instructions :
The label of all products, except those intended solely for
domestic use, must bear explicit instructions about pesticide
disposal. The statements listed below contain the exact wording
that must appear on the label of these products:
1. The labels of all products, except domestic use, must
contain the statement, “Do not contaminate water, food,
or feed by storage or disposal.”
2. Except those products intended solely for domestic use,
the labels of all products that contain active ingredients
appearing on the “Acutely Hazardous” Commercial pesticide
products List (RCRA “E” List) at the end of this appendix
or are assigned to Toxicity Category I on the basis of
oral or dermal toxicity, skin or eye irritation potential,
or Toxicity Category I or II on the basis of acute inhala-
tion toxicity must bear the following pesticide disposal
statement:
“pesticide wastes are acutely hazardous. Improper dis-
posal of excess pesticide, spray mixture, or rinsate is
a violation of Federal Law. If these wastes cannot be
disposed of by use according to label instructions,
contact your State Pesticide or Environmental Control
Agency, or the Hazardous Waste representative at the
nearest EPA Regional Office for guidance.”
The labels of all products, except those intended for
domestic use, containing active or inert ingredients that
appear on the “Toxic” Commercial Pesticide Products List
(RCRA “F” List) at the end of this appendix or presently
meet any of the criteria in Subpart C, 40 CFR 261 for a
hazardous waste must bear the following pesticide disposal
statement:
279
-------
Appendix IV-4
(continued)
“Pesticide wastes are toxic. Improper disposal of excess
pesticide, spray mixture, or rinsate is a violation of
Federal Law. If these wastes cannot be disposed ot by
use according to label instructions, contact your State
pesticide or Environmental Control Agency, or the Hazardous
Waste representative at the nearest EPA Regional Office
for guidance.”
Labels for all other products, except those intended for
domestic use, must bear the following pesticide disposal
statement:
“Wastes resulting from the use of this product may be
disposed of on site or at an approved waste disposal
facility.”
3. Products intended for domestic use only must bear the
following disposal statement: “Securely wrap original
container in several layers of newspaper and discard in
trash. “
C. Container Disposal Instructions
The label of ea ch product must bear container disposal
instructions appropriate to the type of container.
1. All products intended for domestic use must bear one
of the following container disposal statements:
Container Type Statement
Non—aerosol products
(bottles, cans, jars)
Do not reuse container (bottle, can, jar).
Rinse thoroughly before discarding in trash.
Non-aerosol products
(bags)
Do not reuse bag. Discard bag in trash.
Aerosol products
Replace cap and discard containers in
trash. Do not incinerate or puncture.
280
-------
Appendix IV-4
(continued)
2. The labels for all other products must bear container disposal
instructions, based on container type, listed below:
Container Type
Statement
1/ Manufacturer may replace this phrase with one indicating
whether and how fiber drum may be reused.
Metal
containers
(non—aerosol)
Triple rinse (or equivalent). Then offer
for recycling or reconditioning, or puncture
and dispose of in a sanitary landfill, or by
other procedures approved by state and local
authorities.
Plastic containers
Triple rinse (or equivalent). Then offer
for recycling or reconditioning, or puncture
and dispose of in a sanitary landfill, or
incineration, or, if allowed by state and
local authorities, by burning. If burned,
stay_out_of_smoke.
Glass containers
Triple rinse (or equivalent). Then dispose
of in a sanitary landfill or by other
approved state and local procedures.
Fiber drums
with liners
Completely empty liner by shaking and
tapping sides and bottom to loosen clinging
particles. Empty residue into application
equipment. Then dispose of liner in a
sanitary landfill or by incineration if
allowed by state and local authorities.
If drum is contaminated and cannot be
reusedl,_dispose_of_in_the_same_manner.
Paper and
plastic bags
Completely empty bag into application
equipment. Then dispose of empty bag in
a sanitary landfill or by incineration,
or, if allowed by State and local
authorities, by burning. If burned, stay
out of smoke.
Compressed gas
cylinders
Return empty cylinder for reuse (or
similar wording)
281
-------
Appendix IV-4
(continued)
Pesticides that are hazardous wastes under 40 CFR 261.33(e) and (f)
when discarded.
“ Acutely Hazardous” Commercial Pesticides (RCRA “E” List)
Active Ingredients, (no inerts) :
Acrolein
Aldicarb
Al dr in
Allyl alcohol
Aluminum phosphide
4-Aininopyridine
Arsenic acid
Arsenic pentoxide
Arsenic trioxide
Calcium cyanide
Carbon disulfide
p-Chloroanj ljne
Cyanides (soluble cyanide salts, not specified elsewere)
Cyanogen chloride
2—Cyclohexyl —4, 6—dinitropheno ],
Dieldrjn
0 ,0-Diethy ], S— [ 2-ethylthio)ethyl] phosphorodithioate
(disultoton, Di—Syston)
0 ,0-Diethyl 0—pyrazinyl phosphorothioate (Zinophos)
Dimethoate
o , 0-Dimethyl. O—p-nitrophenyl phosphorothioate (methyl parathion)
4,6—Dinitro—o—cresol and salts
4, 6 -Dinitro—o—cyc lohexy lphenol
2,4 Dinitrophenol
Dinoseb
Endosul fan
Endothal. 1
Endrin
Famphur
Fluoroacetamjde
Heptachior
Hexanethyl tetraphosphate
Hydrocyanic acid
Hydrogen cyanide
Methomyl
alpha-Naphthy] .thjourea (ANTU)
Nicotine and salts
Octamethylpyrophosphoramjde (OMPA, schradan)
Parathion
282
-------
Appendix IV—4
(continued)
“ Acutely Hazardous” Commercial Pesticides (RCRA “E” List)
Active Ingredients continued :
Phenylmercuric acetate (PMA)
Phorate
Potassium cyanide
Propargyl alcohol
Sodium azide
Sodium cyanide
Sodium fluoroacetate
Strychnine and salts
O,O,O,O-Tetraethyl dithiopyrophosphate (sulfotepp)
Tetraethyl pyrophosphate
Thallium sulfate
Thiofanox
Toxaphene
War far in
Zinc phosphide
283
-------
Appendix IV-4
(continued)
“ Toxic” Commercial Pesticide Products (RCRA nFH List)
Active Ingredients :
Ace tone
Acrylonitrile
Amitrole
Benzene
Bis( 2—ethyihexyl ) pthalate
Cacodylic acid
Carbon tetrachioride
Chloral (hydrate)
Chiordane (technical)
Chlorobenzene
4—Chloro—m—creso].
Chloroform
o-Chl orophenol
4-Chloro—o—toluidine hydrochloride
Creosote
Cresylic acid
Cyc 1 ohexane
Decachlorooctahydro—l , 3, 4—metheno—2H—cyclobuta Ec ,d] —pentalen—2—one
(kepone, chl ordecone)
1 ,2-Dibromo—3—chloropropane (DBCP)
Dibutyl phthalate
S—3,3-(Dichloroallyl diisopropylthiocarbamate (diallate, Avadex)
o—Dichlorobenzene
p-Dichlorobenzene
Dichiorodifluoromethane (Freon 12®)
3,5-Dichloro—N—(l,l—dimethyl-2—propynyl) benzamide (pronamide,Kerb)
Dichioro diphenyl dichloroethane (DDD)
Dichioro diphenyl trichloroethane (DDT)
Dichlorethyl ether
2,4—Dichiorophenoxyacetic, esters and salts (2,4-D)
1, 2-Dichloropropane
1, 3—Dichloropropane (Telone)
Dimethyl phthalate
Ethyl acetate
Ethyl 4,4’—dichlorobenzilate (chlorobenzilate)
Ethylene dibromide (EDB)
Ethylene dichloride
Ethylene oxide
Formaldehyde
Furfural
Hexachlorobenzene
Hexachiorocyclopentad iene
Hexachloroethane
Hydrofluoric acid
284
-------
Appendix IV—4
(continued)
“ Toxic” Commercial Pesticide Products (RCRA HpN List)
Active Ingredients :
Isobutyl alcohol
Lead acetate
Lindane
Maleic hydrazide
Mercury
Methyl alcohol
Methyl bromide
Methyl chloride
2,2’-Methylenebis (3,4,6—trichiorophenol) (hexachlorophene)
Methylene chloride
Methyl ethyl ketone
4—Methyl-2—pentanone (methyl isobutyl ketone)
Naphthalene
Nitrobenzene
p—Nitrophenol
Pentachloroethane
Pentachloronitrobenzene (PCNB)
Pentaclorophenol
Phenol
Phosphorodithioic acid, 0,0—diethyl, methyl ester
Propylene dichloride
Pyridine
Resorcinol
Saf role
Selenium disulfide
Si 1 vex
1 ,2,4, 5—Tetrachlorobenzene
1 , 1 , 2, 2—Tetrachloroethane
Tetrachioroethylene
2,3,4, 6—Tetrachlorophenol
Thiram
Toluene
1 , 1 , 1—Trichioroethane
Trichioroethylene
Trichloromonofluoromethane (Freon l1)
2,4, 5—Trichioropheno].
2,4, 6—Trichiorophenol
2,4,5—Trichiorophenoxyacetic acid (2,4,5—T)
Xylene
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Appendix IV-4
(continued)
“ Toxic” Commercial Pesticide Products (RCRA “p” List)
Inert Ingredients :
Acetone Formaldehyde
Acetonitrile Formic acid
Acetophenone Isobutyl alcohol
Acrylic acid Meleic anhydride
Aniline Methyl alcohol (methanol)
Benzene Methyl ethyl ketone
Chlorobenzene Methyl methacrylate
Chloroform Naphthalerie
Cyclohexane Saccharin and salts
Cyclohexanone Thiourea
Dichiorodifluoromethane (Freon 12®) Toluene
Diethyl phthalate 1,1 ,l—Trichloroethane
Dimethylainine 1 , 1 , 2 —Trichloroethane
Dimethyl phthalate Trichlorofluoromethafle (Freon ii )
1,4—Dioxane Vinyl chloride
Ethylene oxide Xylene
U.S.V1 NMINTP INTINOO ICI 1985 k9 1 191 1+6101
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