United Stat«           Office of Partteidei and Toxic Substances
                 Environmental Protection     Office of Pesticide Programs (TS-766C»
                 Agency              Washington, DC 20460
v>EPA      Pesticide
                 Fact Sheet
                 Name of Chemical:  APDSURF
                 Reason for Issuance:
                 Date Issued:   Feb. is, 1984
                 Fact" Sheet Number:  17
   1. Description of  Chemical

      Generic name: Poly(oxy-l,2-ethanediyl), alpha-isooctadecyl-
                   omega-hydroxy
      Common name: none
      Trade name:  Arosurf® MSF (Monomolecular Surface Film)
      EPA Shaughnessy code: 124601
      Chemical abstracts service (CAS) number: 52292-17-8
      Year of initial registration: 1984
      Pesticide type: Insecticide (mosquito larvacide/pupacide)
      Chemical family: ethoxylated fatty alcohol  (a nonionic
                      surfacant
      U.S.  producer:  Sherex Chemical Company,  Inc.

   2.  Use Patterns and Formulations

      Application sites: Semi-permanent or permanent  fresh
        (including potable and irrigation sources)  or  salt
        water  habitats.  Semi-permanent or permanent polluted
        water  habitats.
      Types of  formulations:  liquid
      Types/methods of application:  ground and air  spray
      Application rates: 3-5 gal/acre  (i.e., 0.2-0.5 gal.
         a.i./acre
      Usual carriers:  water

   3.  Science Findings

        Summary science findings:

        Based on submitted  toxicity  and  fish and wildlife data,
        Arosurf® demonstrates  low toxicity  to  humans, fish
        and wildlife.   The  product  is  conditionally registered
        pending the submission of additional fish and wildlife
        studies identified  below.

     Chemical characteristics;

       Arosurf® MSF  is  a clear, light amber liquid at 77°F
       with a melting point of 19-27°F and a flash point of
        395°F.  It  is  capable of reducing the surface tension
       of clean water to 28.2 dyns/cm at 77°F.  As a surfactant,
        it forms a  film over the surface of the water to which

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it is applied. Its mode of action is considered to be
physica’ rather than chemical in that it reduces the
water surface tension resulting in suffocation of the
larvae and pupae.
Toxicology Characteristics :
Arosurf MSF demonstrates low toxicity (Tox Category
III) from the following submitted studies:
— Two oral LD 50 rat studies; 20 gm/kg and 5.0 gm/kg
— Eye irritation, rabbit; not -an eye irritant
— Primary eye irritation, rabbit; not an eye irritant
— Acute LC 50 inhalation, rat; >29 mg/L
— Salmonella znicrosomal Ames mutagenicity assay;
negative
— Primary skin irritation, guinea pig; mild dermal
irritant
— Primary skin irritation, rabbit; severe dermal
irritant with reversibility of effect
— Primary skin irritation, human patch test; not a
skin irritant
— 2—year dog study with a NOEL of 50,000 ppm (1250 mg/kg)
— Two 2—year dog studies with NOEL of 20,000 ppm
(1,000 mg/kg)
— 10—month monkey study with a NOEL of 1,000 mg/day
Physiological and Biochemical Behavior Characteristics :
Foliar absorption: N/A
Translocation : N/A
Mechanism of pesticidal action: suffocation (physical)
Metabolism and persistence in plants and animals: N/A
Environmental Characteristics :
Adsorption and leaching in basic soil types: N/A
Microbial breakdown: data show that the chemical is
degraded by unaclimated, mixed cultures trom natural
sources by the shake culture method.
Loss from photodecomposition and/or volatization: Arosurfe
MSF is stable to hydrolysis and aqueous photolysis in
the absence of photosensitizers.
Bioaccumulation: Similar alcohol ethoxylates degrade under
field conditions with the major route of degradation
being hydrolysis at the ether linkage and subsequent
oxidation of the alkyl chain to lower molecular weight
polyethylene glycol—like materials and ultimately CO 2
and H 2 O.
Resultant average persistance: 2 to 10 days at recommended
dosage rates.

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Ecological Characteristics :
Hazards to fish and wildlife: the following data have been
subm 4 tted:
— Avian acute oral LD 50 (mallard duck); >2,000 mg/kg
— Avian dietary LC 50 (bobwhite quail); >5,000 mg/kg
— Fish acute LC 50 (bluegill); 290 mg/L.: and rainbow
trout; 98 mg/L
— Aquatic invertebrate LC 50 (Daphnia); 1.9 mg/L
Efficacy review results :
Efficacy data not required.
Tolerance Assessments :
An exemption from the requirement of a tolerance for the
pesticide in or on fish, shellfish, irrigated crops, meat,
milk, poultry and eggs, when used as a mosquito control
agent in aquatic areas has been established under 40 CFR
180.1078.
Studies on closely related fatty acid and fatty alcohol
ethoxylates having various degrees of ethoxylation
supported the clearance of the chemical as an inert
ingredient and were also used in support of the exemption
as an active ingredient.
4. Summary of Regulatory Position and Rationale
Use classification: General
Use, formulat-ion, manufacturing process or geographical
restrictions : None
Unique warning statements required on labeling: None
Summary of risk/benefit review: None conducted
It has been determined that (1) the use of Arosurf MSF
has met the public interest finding as required for the
conditional registration of a new chemical under section
3(c)(7)(C) of FIFRA, as amended; and (2) that the use of
the pesticide during the period in which the requested
data is being generated will not cause any unreasonable
adverse effect on the environment.
5. Summary of Major Data Gaps
— One avian dietary study on mallard duck (submitted
and currently under review)
— One fish early lifestage study

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— One aquatic invertebrate (Mysid shrimp) lifecyle study
These studies are to be submitted no later than February 1,
1987.
6. Contact person at EPA
William H. Miller
Product Manager (16)
Insecticide—Rodenticide Branch
Registration Division (TS—767)
Environmental Protection Agency
Washington, DC 20460
Tel. No. (703) 557—2600
DISCLAIMER: The information presented in this Chemical Information
Fact Sheet is for informational purposes only and may not be used
to fulfill data requirements for pesticide registration and
reregistration.

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