United State* Office of Pesticide* ind Toxic Substances
Environmental Protection Office of Peitiade Programs (TS-766C)
Agency Washington, DC 20460
Pesticide
Fact Sheet
Name of Chemical: SULFURYL FLUORIDE
Reason for Issuance:
Date Issued: June 30, 1985
Fart Sheet Number:
1. Description of Chemical
Generic Name: Sulfuryl Fluoride
Common Name: Vikane
Trade Name: N/A
EPA Shaughnessay Code: 078003
Chemical Abstracts Service (CAS) Number: 2699-79-8
Year of Initial Registration: December 15, 1959
(EPA Reg. No. 464-236)
Pesticide Type: Structural Fumigant
Chemical Family: Inorganic Acid Halides
Producers: US Dow Chemical Company
Foreign None
2. Use Patterns and Formulations
Application Sites: Domestic dwellings and contents; Wood or
wood structure treatment;
Commercial, Institutional and Industrial areas;
Surface Ships in ports; Vehicles
Types of Formulations: Liquified Gas under pressure
Application Rates: Metered release at concentrations
measured in ounce-hours, i.e. ounces of fumigant
per cubic feet of space, multiplied by the time
in hours. The ounce-hour requirements depend on
temperature, degree of leakage, etc.
Usual Carriers: N/A
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Sulfuryl fluoride 2
fact sheet
3. Science Findings
Chemical Characteristics:
Physical State: liquified gas under pressure
Color: Colorless
Odor: None
Melting Point: —136.67°C at 760 mmHg
Density: 3.72 g/l
Solubility:
In Water (25°C) 0.075 g/l00 g
In Wesson Oil (20°C) 0.780 g/lOO g
In Acetone (22°C) 1.740 g/lOO g
In Chloroform (22°C) 2.120 g/l00 g
Toxicity Characteristics
Sulfuryl fluoride is an extremely hazardous gas or
liquid under pressure. Inhalation of vapors may be
fatal. Contact with the liquid may cause freezing,
injury, or burn to eyes, mucous membranes, or skin,
with delayed onset of symptoms. Sulfuryl fluoride
has no warning properties such as odor or lacrirna—
tion or eye irritation. Early symptoms of over ex-
posure are respiratory irritation (distress),
pulmonary edema, nausea, and abdominal pain. Re-
peated exposure to high concentrations can result in
lung and kidney damage. Single exposures at high
concentrations have resulted in death. Respiratory
equipment and protective clothing are required to
use sulfuryl fluoride safely.
Available Data:
Inhalation LC 50 17.5 mg/liter (20 . g/cubic meter)
Toxicity Category by this route is III.
No other acute toxicity available or required by the
guidelines because the pesticide is a gas.
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Sulfuryl fluorlxie
fact sheet
3
Threshold Limit Value (TLV )1/ is 5 ppm (20 mg/rn 3 );
the level to which persons may be exposed daily
for an 8 hour work day without adverse effects
Short Term Exposure Limit (STEL) is 10 ppm (40 mg/rn 3 );
the level to which persons may be exposed continu-
ously for 15 minutes without adverse effects
Teratology (rabbit, inhalation)
Teratogenic NOEL more than 225 ppm (HDT)
Maternal NOEL 75 ppm
Maternal LEL 225 ppm (decreased body weight gain)
Fetotoxic NOEL 75 ppm
Fetotoxic LEL 225 ppm (decreased body weight and de-
creased rump—crown length)
Levels tested: 0, 25, 75, 225 ppm during days 6—18
of gestation for 6 hrs/day by inhalation
Teratology (rat, inhalation)
Teratogenic NOEL more than 225 ppm (HDT)
Maternal NOEL more than 225 ppm (HDT)
Fetotoxic NOEL more than 225 (I1DT)
Levels tested: 0, 25, 75, 225 ppm during days 6—15
of gestation for 6 hours per day, via inhalation
Physiological—Biochemical Behavioral Characteristics N/A
Environmental Characteristics
Indoor uses only; No expected exposure.
Ecological Characteristics
Indoor uses only; No expected exposure.
Efficacy Data: N/A. Non—Health related uses only.
1/ Threshold Limit Values for Chemical Substances in
the Work Environment adopted by the American Conference
of Government Industrial Hygienists, 1983—84.
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&ilfuryl fluoride 4
Lact sheet
4. summary of Regulatory Position and Rationale :
Because of the inhalation hazard associated with this
chemical it is being classified as a restricted use
pesticide.
Unique Warning Statements:
RESTRICTED USE PESTICIDE DUE TO ACUTE INHALATION HAZARDS
For sale to and use only by Certified Applicators or per-
sons directly under their direct supervision, and only
for those uses covered by the Certified Applicator’s
certification. Special respiratory equipment, protective
clothing, and training are req .iired for safe use of this
pesticide. Placarding of treated areas required. Re-
entry only permitted after work area is determined to
contain no residuals greater than 5 ppm of sulfuryl
fluoride as determined by direct reading monitoring device.
Tolerance Assessments: N/A The registered uses of Sulfuryl
fluoride do not include direct application to a food or
feed crop.
Problems which are known to have occurred with use of the
chemical (e.g., PIMS): none.
5. Summary of major data gaps :
Residue data from household articles required to establish
residues in treated articles and surfaces in habitable
structures to which residents may be exposed upon re—entry
of fumigated structures (dwellings).
6. Contact person at EPA : A. E. Castillo
Product Manager (32)
Disinfectants Branch
Registration Division (TS—767c)
Tel. (703) 557—3964
DISCLAIMER: The information presented in this Chemical
Information Fact Sheet is for informational purposes
only and may not be used to fulfill data requirements for
pesticide registration and re—registration.
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