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MARCH 1984
STATUS REPORT
on
REBUTTABLE PRESUMPTION AGAINST REGISTRATION (RPAR) OR SPECIAL REVIEW CHEMICALS,
REGISTRATION STANDARDS PROGRAM, AND DATA CALL-IN PROGRAM
(Report contains information as of March 31, 1984)
OFFICE OF PESTICIDE PROGRAMS (TS-767C)
U.S. ENVIRONMENTAL PROTECTION AGENCY
401 M STREET, S.W.
WASHINGTON, D.C. 20460
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TABLE OF CONTENTS
RPARs Issued 1
PRE-RPAR Review 5
Final Actions (Voluntary Cancellations) 6
Notice of Intent to Cancel/Suspend 8
Notice of Intent to Register (Returned to Registration Div.) 10
RPAR1 s Completed 16
Registration Standards Development - Data Collection 26
Registration Standards Development - Data Evaluation and
Development of Regulatory Position....* 28
Registration Standards Issued 31
Data Call-in 40
Index of Chemicals Included in Status report 50
Prepared by:
Registration Support and
Emergency Response Branch
Registration Division
(703) 557-7700
Date Prepared: June 1984
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REGISTRATION DIVISION
DIRECTOR
DEPUTY DIRECTOR
Insecticide-Rodenticide
Branch
PM 12 Jay Ellenberger
PM 15 George LaRocca
PM 16 William Miller
PM 17 Timothy Gardner
Fungicide-Herbicide
Branch
PM 21 Henry Jacoby
PM 23 Richard Mountfort
PM 25 Robert Taylor
Disinfectants Branch
PM 31 John Lee
PM 32 Arturo Castillo
Special Review Branch
Registration Support and
Emergency Response Branch
DATA CALL-IN PROGRAM
Douglas D. Campt
Robert V. Brown
Herbert Harrison
James Akerman
Juanita Wills
Paul Lapsley
Ferial Bishop
Geraldine Werdig
(703) 557-7760
(703) 557-7760
(703) 557-2200
(703) 557-2386
(703) 557-2400
(703) 557-2600
(703) 557-2690
(703) 557-1650
(703)
(703)
(703)
(703)
(703)
(703)
(703)
(703)
557-1900
557-1830
557-1800
557-3661
557-3675
557-3965
557-7420
557-7700
(703) 557-7436
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PREFACE
This publication contains: 1) an alphabetical listing of all chemicals which have been, or are
being, handled under the Rebuttable Presumption Against Registration [RPAR] process, (revisions
to the process and name change to Special Review are planned), 2) an alphabetical listing of the
chemicals which have been through or are now active in the Registration Standard development
process, and 3) identification by cluster of the chemicals which have been through or are being
processed in the Data Call-in program. -These processes are managed by the Registration Division,
Office of Pesticide Programs, Office of Pesticides and Toxic Substances, EPA.
This listing is intended for internal use and is updated semi-annually. Users of this
document are encouraged to contact the appropriate PM or Branch Chief, as noted, if they have
any questions or corrections regarding the entries in this listing.
Sections of the law referred to in this document are from the Federal Insecticide,
Fungicide and Rodenticide Act (FIFRA) as amended 7 U.S.C. Section 136.
All chemicals are listed by the names under which they were or are being reviewed. Other widely
used common or chemical names may also appear in the Index.
Copies of most of the position documents (PD) and Registration Standards are available from the
National Technical Information Service (NTIS), U.S. Department of Commerce, 5285 Port Royal Road,
Springfield, Virginia, 22161 (703) 487-4600. The accession number and costs for paper copy
and/or microfiche are cited for those documents presently available from NTIS.
When requesting documents from the NTIS, state the name of the document, the NTIS publication (PB)
Accession Number, enclose proper payment (check payable to NTIS) and provide a return
mailing address.
RPAR PROCESS*
Definitions of the risk criteria that, when met or exceeded, can trigger RPAR analyses,
can be found in the Federal Register of July 3, 1975 (40 CFR 162.11). These risk criteria
are concerned with the following areas:
1. Acute Toxicity
2. Chronic Toxicity
A. Oncogenic
B. Mutagenic
*This processis undergoing revision via rulemaking and a name change to "Special Review Process'
is contemplated.
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3. Other Chronic Effects
A. Reproductive
(1) Fetotoxicity
(2) Teratogenicity
B. Spermatogenicity
C. Testicular Effects
D. Neurotoxicity
E. Others
4. Significant redaction in wildlife, reduction in endangered species, and reduction in
nontarget species.
5. Lack of emergency treatment or antidote.
RPAR CATEGORIES
The name of this process will be changed from "RPAR" to "Special Review" pursuant to the new
regulations which are planned for proposal in the near future. That is why for purposes of this
report the terms may be used interchangeably. This report is divided into a number of categories
to enable the reader to conveniently determine the current status of a particular pesticide.
Pre-RPAR — This is the initial risk investigation phase that involves an intensive review of
the scientific studies of the chemical in question that suggest that the RPAR criteria may have
been exceeded. A validation of these studies of the chemical in question is conducted by Agency
scientists. During this period, the registrants of the pesticide are informed of the review and
are often requested to submit additional information. If "trigger studies" are found to be
valid, an effort is made to gather and preliminarily assess available information on the exposure
to the pesticide. If such data are not available, the Agency extrapolates from models or analogs
and develops exposure assumptions to hypothesize the potential risk of the pesticide under
review. Major "trigger studies" undergo peer review (in accordance with Section 25e of FIFRA)
to confirm the EPA validation. Discussions are held with registrants and other interested
parties in an attempt to reduce exposure to acceptable levels. If the risk is reduced, or is
found through review to be acceptable, the RPAR review is terminated.
If risk is determined to be unacceptable, the validation of the "trigger studies" and the
combination of this hazard information with the exposure analysis produce the Agency's
preliminary position on the potential risk of the pesticide. The document describing this
position on risk is referred to as position document one (PD 1). Upon approval by the Agency, a
notice of the availability of the PD 1 along with a formal Notice of Rebuttable Presumption
Against Registration is published in the Federal Register.
ii
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Issuance of an RPAR—After a PD 1 is published, a 45 day period is allowed for comment
on the presumptions against registration presented in PD 1. A 60 day extension is granted,
if justified. Therefore, there is typically a 105 day period within which the Agency's
presumptions may be rebutted.
Risks may be rebutted by interested parties submitting to the Agency: (1) proof that the
study or studies upon which the presumption is based are not scientifically valid or (2)
proof that actual exposure to the compound will not cause the effects described. This phase
of the process can be characterized as focusing on the gathering of additional information
in the form of:
--rebuttal comments.
—additional information on risk.
--input from other agencies: primarily the United States Department of
Agriculture for information on benefits and exposure, and the United States
Department of Interior, Office of Endangered Species for information on the
implications of an environmental trigger.
In the event that all the triggers have been successfully rebutted, the pesticide is re-
turned to the registration process and the RPAR is terminated for all or some of the uses.
The results of this phase of the analysis is incorporated into a second position document
(PD 2) which states the Agency's regulatory action for the pesticide. Any new information
surface during the rebuttal period is, of course, incorporated. If the rebuttal is successful
for all or some of the uses, a PD 2 is published and becomes the final document of the RPAR
process. The Agency only produces and publishes a separate PD 2 in those cases where the
rebuttal has been successful. When the rebuttal is not successful, the rebuttal assessment,
the risk analysis, the benefits analysis, risk/benefit synthesis and the proposed regulatory
position are presented in a document termed PD 2/3.
A PD 2/3 is composed of:
—the introductory chapter which reviews the RPAR criteria whicn gave rise to the
RPAR on the pesticide in question,
—the risk analysis which reviews rebuttal comments, estimates exposure and calculates
risks for the registered uses of the pesticide,
—the benefit analysis which represents the impact of total cancellation of the
pesticide in question,
—the risk/benefit analysis of each of the regulatory options under considera-
tion for resolution of the RPAR, and
--the recommended regulatory position.
iii
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The full range of regulatory options which are available under the law are examined. These
range from full registration to full cancellation. Between the two ends of the regulatory
spectrum are the options that deal with labeling changes, classification, and use restric-
tions. The impact of each of these options on the benefits and risk of each use of the
pesticide are considered. The recommended decision is that which presents the best balance
of risks and benefits in the interest of public health and the environment.
At the conclusion of the risk/benefit evaluation, the completed PD 2/3 receives Agency review.
Discussions may be held with registrants and other interested parties. If the Assistant
Administrator for the Office of Pesticides and Toxic Substances approves this document, a
notice of preliminary determination and an announcement of the document's availability are
published in the Federal Register.
The FIFRA requires that the proposed decision (PD 2/3) be submitted to a Scientific
Advisory Panel for review of its scientific basis and to the Secretary of Agriculture for
comment. These comments, plus any industry or public comments on the proposed decision, are
evaluated. The Agency's assessment of these comments, including the final decision on the
regulatory action, are announced in the Federal Register. These are contained in publi-
cation PD 4 which is also announc.ed in the Federal Register.
Activities After Completion of RPAR's—This document describes the status of those chemicals
that have,through a variety of means, concluded their RPAR analyses. This includes chemicals
which have been returned to the registration process, those which have been cancelled or on
which restrictions have been imposed, and those which are currently in administrative hearings
hearings, being reviewed in court, etc.
REGISTRATION STANDARDS
The Registration Standards program is EPA's approach to the reassessment and reregistra-
tion of pesticide products as mandated by Congress in FIFRA Section 3 (g). The reassessment
involves a thorough review of the scientific data base underlying pesticide registrations and
an identification of essential but missing scientific studies which may not have been required
when the product was initially registered. It may also require new testing or retesting to
ensure the safety of the compound by contemporary scientific standards.
IV
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The standards process involves making broad regulatory decisions at one time for a group
of pesticide products containing the same active ingredient rather than on a product-by-
product basis. About 600 active ingredients, representing 35,000 currently-registered
products could potentially require Registration Standard review. However, given assump-
tions about chemicals not requiring review due to voluntary cancellations, suspensions,
and other reasons, the actual number of standards to be developed is substantially less
than that. This approach to reregisration is intended to simplify and streamline the
regulatory process for both the Agency and pesticide registrants and to assure the public
that all registrations are supported by a complete and valid scientific data base.
To establish the sequence of processing the approximate 600 active ingredients through the
Registration Standard review, active ingredients that have similar use(s) have been
clustered into 48 groups. The groups are being processed in a sequence resulting from
their ranking in an equation based on production, human exposure, and ecological exposure
factors. The ranking scheme was developed based on consideration of market competition,
availability of in-depth data on alternatives should the need for a Special Review arise,
and efficient use of EPA resources.
Each standard explains EPA's regulatory position on the use of the active ingredient in
all pesticide products containing that same chemical. The standard contains an anal<
of the data on
regulatory pos
product registration.
e Apj.ci J. us CjCn o JL cy u J-L y p«_it> j. i_ j_vjii >_MI i_nc uoc >jj_ uiic av-t-ivc i. uy i. cu icu <_ J-ii
products containing that same chemical. The standard contains an analysis
which the regulatory position is based, describes the rationale for the
ition, and states the conditions that must be met to obtain pesticide
The relationship of the Registration Standards, process with the Special Review process
is that if the analysis of the data shows that a Special Review criterion has been met,
then the standard is issued announcing, that a Special Review will be initiated for some or
all of the uses of the chemical and a proposed regulatory decision or "PD 2/3" will be issued,
Registration Standards are developed in three phases: (1) Data Gathering, (2) Data
Evaluation, and (3) Regulatory Position Development followed: by the issuance of the
Registration Standard Guidance. Package.- For convenience, phases 2 and 3 are combined
in this report and the issued documents are identified separately in the attached listing.
(1) Data Gathering; The bibliography consists of all data in Agency files pertaining to the
chemical, except that in most cases efficacy data are not listed. The bibliography will
also include any government studies (such as NCI studies) which have been conducted on the
chemical and other relevant material identified by Agency scientists.
-------
Agency scientists identify which studies should be reviewed; after which, hard copy of all
requested studies are retrieved from Agency files and provided to Agency scientists for
review. The data gathering phase lasts about five months.
Once the data-gathering phase is completed, and the use information is developed, the
data evaluation phase is ready to begin.
(2) Data Evaluation; At the outset of the Data Evaluation phase, the Project Support Team,
which consists of all Agency staff involved in the Registration Standard review (Regis-
tration/reregistration Product Manager, use experts, data retrieval experts, and Agency
scientists) meet to exchange information regarding the chemical from a regulatory and
scientific perspective. This meeting is designed to provide a context in which the scien-
tists conduct their review. Knowledge of the regulatory history, the growth patterns of
the chemical's use, general understanding of the completeness of the data base, and
discussion of any past regulatory/health problems will help focus the review and increase
the scientists' effectiveness.
With this perspective, scientists review data in each of five disciplines: product
chemistry, environmental fate, residue chemistry, toxicology, and ecological effects.
Efficacy data are reviewed only for products which control infectious microorganisms and
the growth of aflatoxins. The scientists document their review of each study which they
consider relevant, and prepare a summary of what is known about the chemical in their
respective discipline. Scientists also identify gaps in the data base which should be
filled to enable a complete scientific assessment to be made. While the 40 CFR Part 158
guidelines* (currently proposed) are used as guidance to make the determination of data
gaps, each chemical is reviewed individually to determine, given its particular use
patterns and what is already known about it, what additional data are needed. If the
resulting data needs differ from those i-n the Guidelines, the scientist provides written
justification for the deviation. Depending on the size of the data base involved in the
review, this phase usually lasts from six to ten months.
*See p.viiifor specific citation.
vi
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(3) Development of Regulatory Position and Issuance of Guidance Package; Once the Science
review is completed and scientists have recommended which additional data they believe are
necessary to complete the review, the Project Support Team reconvenes to identify the
appropriate regulatory position for the chemical (that is, what percent active ingredient,
formulations, uses, etc. are registerable under the Standard and whether regulatory
restrictions such as label warnings or use by certified applicators only are required).
They also develop the rationale for the regulatory position and determine the data
requirements which need to be imposed to complete the review. Included in this phase is
the tolerance reassessment which may result in the initiation of rulemaking to increase or
decrease tolerance levels. A document summarizing these findings, including the proposed
regulatory position and rationale, data requirements, scientific summaries, and bibliography,
is then circulated to Agency management for review.
After the document is approved, study reviews and science summaries are placed in Agency
records for retrieval during subsequent reviews of the chemical (e.g. registration amendments)
as their availability is expected to expedite the processing of future reviews. Copies of
the study reviews and the science summaries are available through OPP's Freedom of Information
Section. The regulatory position/ rationale, data requirements, and bibliography are
sent to the registrant in a document known as a Guidance Package which cites the authority
of Section 3(c)(2)(B) and Section 3 (g) of FIFRA. Reregistration occurs when the registrant
agrees to comply with the data requirements, submits an updated Confidential Statement of
Formula if needed, agrees to comply with any regulatory restrictions placed on the chemical,
agrees to compensate other registrants for data considered relevant to the Standard, and
provides labelling reflecting completion of any product chemistry and acute toxicity data
requirements.
Issuance of the Standard; The standard is issued to the registrants and made available
to the public through the National Technical Information Service, 5285 Port Royal Road,
Springfield, VA 22152 telephone 703-487-4650. Microfilm copies are available for $4.50;
the price of paper copies varies according to the length of the document. Please furnish
NTIS with the accession number or the PB number when ordering.
v 11
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THE DATA CALL-IN PROGRAM
Tne Data Call-in Program requires existing registrants of active pesticide chemicals to
provide the Agency with needed studies under Section 3(c)(2)(B) of FIFRA. Such studies,
including chronic toxicilogy, product chemistry, residue and environmental fate data
are an integral part of the data base used to reassess each chemical during the
reregistration process or to resolve special concerns such as whether the chemical
enters groundwaters.
The purpose of Data Call-in is to assure that these data are available or well underway
before the pesticide chemical is reassessed for reregistration under Section 3(g) or
other purposes.
The four types of long-term toxicological data which have been traditionally requested
consist of C_hronic Feeding, (Dncogenicity, ^Reproduction and Teratogenicity (informally
referred to as the CORT studies). These studies are described in the Toxicology Data
Requirements' part of the "Pesticide Registration: Proposed Data Requirements"
regulation.* The product chemistry, residue, and environmental fate studies are also
described in this regulation.
Under the Data Call-in Program, the Agency: (1) determines which types of data are
required for each chemical, based on its use patterns and other factors; (2) identifies
those test categories with no valid data submitted; and (3) ensures that studies are
initiated by registrants of the pesticide to fill those data gaps.
In general, the sequence of processing the approximate 600 active ingredients through
the Data Call-in process is based on the priority cluster ranking in which active
ingredients that have a similar use(s) are clustered into about 50 groups and the groups
are processed in sequence. A notice of the availability of the final cluster ranking was
published in the Federal Register, 47 FR 3770, January 24, 1982. The cluster ranking is
not followed when special concerns arise about a chemical or a particular group of
chemicals.
*The Pesticide "Registration Guidelines were reproposed as Part 158, 40 CFR on
November 24, 1982 in 47 Federal Register 53192.
viii
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In each Notice, the registrant can request the Agency to exempt or waive any or all of the
specified data requirements. Registrants may request changes of or exemptions from the data
requirements because:
1. They believe they are a formulator or end-user.
2. They determine that their chemical involves only minor exposure and production.
In addition, registrants may cite economic factors as precluding its capacity to
incur the costs of testing.
3. They wish to remove all registered uses which involve food crops/products and/or
significant repeated exposure to humans and the environment.
4. They believe the data requirements do not apply to the registered uses of their
product(s) .
If the Agency does not grant the change(s) or exemption(s), the registrants must arrange to
comply with the Notice.
If a registrant does not respond or comply with the Data Call-in Notice, the Agency issues
an Administrative Notice (NOIS—^otice Of latent to ^Suspend) compelling the registrant to
stop distributing the particular.pesticide product(s) until compliance with the Notice
occurs. The actual effect of a NOIS is to put a registration "on hold" until such time
as the registrant wishes to make his registration active. Any such NOIS issued under
Section 3(c)(2)(B) is rescinded when the Agency is informed and agrees that compliance
occurs. Such NQIS's never, independently, result in cancellations and are therefore clear-
ly different from the FIFRA Section 6 suspensions which can later become cancellations
and cause the withdrawal of pesticide products from the market.
This report gives the status of chemicals and clusters being processed through Data
Call In. The status includes whether a Notice or equivalent has been issued and whether
the Agency has reached a final decision on all the waivers, exemptions, cancellations,
commitments and offers received from registrants.
IX
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RPAR's ISSUED
March 1984
CHEMICAL (Class Of
Chemicals) and
CONTACT PERSON
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
CADMIUM
(Special Review Br.)
o Oncogenicity
o Mutagenicity
o Teratogenicity
o Fetotoxicity
o PD 1 published, 42 FR 56574 on
10/26/77; comment period
closed 2/10/78.
o Risk/benefit assessment is planned
for in FY 85.
CAPTAN
(Special Review Br. )
CARBON TETRACHLORIDE
(Special Review Br.)
COAL TAR
(Special Review Br.)
o Oncogenicity
o Mutagenicity
o Other Chronic Effects
o Oncogenicity
o Toxic effects on
liver and kidney
o Oncogenicity
o Mutagenicity
o PD 1 published, 45 FR 54938 on
8/18/80; comment period closed
12/1/80: NTIS# PB81 109449.
o Risk/benefit assessment is ongoing.
o PD 1 published, 45 FR 68534 on
10/15/80; comment period
closed 11/24/80: NTIS# PB80 121782.
o Risk/benefit assessment is ongoing.
PD 1 published, 43 FR 48154
(10/18/78); comment period closed
9/30/78: NTISf PB80 213879
PD 2/3 (wood uses only) completed
and Notice of Determination pub-
lished in 46 FR 13020 on 2/19/81;
comment period closed 5/20/81;Report
f 540/9-82-004; NTISf PB82-229956
At 4/14/83 public-meeting, proposed
conclusion presented. Comment period
closed 5/13/83.
Final decision is being developed.
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RPAR's ISSUED - Conc'd
March 1984
CHEMICAL (Class
Chemicals) and
CONTACT PERSON
of
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
CREOSOTE
(Special
Review Br.)
EPN
Ethyl p-nitro-
pnenyl thionoben-
zenephosphonate
(PM-12)
ETHYLENE OXIDE
EtO
(Special Review
Br.)
o Oncogenicity
o Mutagenicity
o Neurotoxicity
o Oncogenicity
o Mutagenicity
o Testicular Effects
o Same as above (Coal Tar/Creosote
Coal Tar Neutral Oil PD 1 and
PD 2/3 combined). NTIS# PB82-229956
o PD 2/3 (wood uses only) completed
and Notice of Determination pub-
lished in 46 FR 13020 on 2/19/81;
comment period closed 5/20/81. Report
I 540/9-82-004 NTIS# PB82-229956
o At 4/14/83 public meeting proposed
conclusion presented. Comment period
closed 5/13/83.
o Final decision is being developed.
o PD 1 published 44 FR 54384 on
9/19/79; comment period closed
12/29/79: NTIS# PB80 216815
o Final Notice of Determination and
Decision Document forwarded to
Acting AA on June 30,1983.
o Final Notice of Determination signed
by Acting AA and published 48 FR 39494
on 8/31/83.
o PD 1 published 43 FR 3801 on
1/27/78; comment period closed
5/15/78: NTIS# PB80-213903
o Label changes requiring modification in
workplace design and workplace practice
for sterilization of equipment and sup-
plies used in hospitals and health care
facilities signed on 3/30/84.
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RPARs ISSUED - Cont'd
March 1984
CHEMICAL (Class of
Chemicals) and
CONTACT PERSON
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
INORGANIC O
ARSENICALS O
Arsenic Acid, o
Arsenic Pentoxide,
Arsenic Trioxide,
Sodium Arsenate,
Ammonium Arsenite,
Sodium,
Pyroarsenate,
Lead Arsenate
Basic and Standard)
Calcium Arsenate,
Sodium Arsenite,
Copper Acetoarsenite
(Special Review Br.)
PENTACHLOROPHENOL o
AND DERIVATIVES o
(Special Review Br.) o
Oncogenicity
Mutagenicity
Teratogenicity
Oncogenicity
Fetotoxicity
Teratogenicity
PD 1 published 43 FR 42867 on
10/18/78; comment period closed
2/12/79.
PD 2/3 (wood uses only) completed
and Notice of Determination pub-
lished 46 FR 13020 on 2/19/81;
comment period closed 5/20/81;
At 4/14/83 public meeting proposed
conclusion presented. Comment
period closed 5/15/83.
Final decision being developed and
not due until FY 1985.
PD 1 published 43 FR 48443 on
10/18/78; comment period closed
2/12/79: NTISt PB81-109464.
PD 2/3 (wood used only) completed
and Notice of Determination pub-
lished 46 FR 13020 on 2/19/81;
comment period closed 5/20/81;
At 4/14/83 public meeting proposed
conclusion presented. Comment
period closed 5/13/83.
Final decision being developed.
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RPAR's ISSUED - Cont'd
March 1984
CHEMICAL (Class of
Chemicals) and
CONTACT PERSON
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
STATUS
SODIUM FLUORO-
ACETATE (1080)
(Special Review Br. )
Reduction in Non-target
and Endangered Species
No antidote
2,4-5-TRICHLORO-
PHENOL
(Special Review Br. )
o Oncogenicity
o Fetotoxicity
PD 1 published 41 FR 52792 on
12/1/76; comment period closed
3/15/77: NTISt PB80-216823
PD 2/3 signed on 11/11/82.
Release delayed to coincide
with that of document addressing
predator issues in early 1983.
PD 2/3 resigned by Acting AA on
6/29/83.
SAP reviewed PD 2/3 on 12/83.
Record still open—SAP will issue
final report following 6/12/84
SAP meeting.
PD 1 published 42 FR 41268 on
9/15/78; comment period closed
11/17/78.
Possibility of TCDD contamination
under investigation.
Some voluntary cancellations and
reformulations being processed.
3(c)2(B) letter will be issued in
FY 1984 requesting updated Confiden-
tial Statement of Formula and an
analysis for dioxin contamination.
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PRE-RPAR REVIEW
March 1984
CHEMICAL (Class of
Chemicals) and
CONTACT PERSON
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
RONNEL o
0-(2,4,5-trichlo- o
rophenyl) phosphoro-
thioate (related to
2,4,5-T)
(Special Review Br.)
Oncogenicity
Fetotoxicity
No action; pending 2,4,5-T hearing
which may commence in fall 1984.
3(c)(2)(B) letter will be sent to
registrants to update Confidential
Statement of Formula in FY 84.
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FINAL ACTIONS
VOLUNTARY CANCELLATIONS OF RPAR CHEMICALS
March 1984
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
ACRYLONITRILE
(three products)
ARSENIC TRIOXIDE
o Oncogenicity
o Teratogenicity
o Neurotoxicity
o Oncogenicity
o Mutagenicity
o Teratogenicity
BENZENE o Oncogenicity
(all except one product) o Mutagenicity and
Blood Disorders
BHC
CHLORANIL
CHLORDECONE
Kepone
(Products of six
formulators)
COPPER ACETOARSENITE
o Oncogenicity
o Oncogenicity
o Oncogenicity
o Oncogenicity
o Mutagenicity
o Teratogenicity
o 43 FR 26310 (6/19/78).
o 42 FR 45944 (9/13/77).
o Voluntary cancellations
completed.
o 43 FR 31432 (7/21/78)
NTIS# PB80-216781
o 42 FR 3702 (1/19/77).
o 42 FR 38205 (7/27/77)
NTIS# PR80-216773
O 42 FR 18422 (4/7/77).
COPPER ARSENATE (Basic)
(all products)
ERBON
o Oncogenicity
o Oncogenicity
o Teratogenicity
o Fetotoxicity
O 42 FR 18422 (4/7/77).
O 45 FR 58770 (10/4/80).
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FINAL ACTIONS
VOLUNTARY CANCELLATIONS OF RPAR CHEMICALS - CONT'D
March 1984
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
ISOCYANURATES
(some products)
MONURON
(some products)
NITROFEN (TOK)
OMPA
OctamethyIpyro-
phosphoramide
PERTHANE
(many products)
PHENARSAZINE CHLORIDE
SAFROLE
SODIUM ARSENITE
(two products)
STROBANE
TRYSBEN
o Kidney effects
o Oncogenicity
o Teratogenicity
o Mutagenicity
o Oncogenicity
o Oncogenicity
o Oncogenicity
o None
o Oncogenicity
o Mutagenicity
o Oncogenicity
o Mutagenicity
o Teratogenicity
o Oncogenicity
o Oncogenicity
o Registrants have either
undertaken or scheduled
numerous toxicological
studies.
o 42 FR 41320 (8/16/77).
o Product voluntarily can-
celled on 9/15/83.
o 41 FR 21859 (5/28/76).
o 45 FR 41694 (6/20/80).
O 42 FR 59776 (11/21/77),
o 42 FR 11039 (2/25/77).
o 42 FR 16844 (3/30/77).
o 42 FR 29957 (6/10/77).
o 43 FR 48267 (10/18/78)
o 41 FR 26607 (6/28/76).
o 43 FR 5782 (2/9/78).
-------
NOTICE OF INTENT TO CANCEL/SUSPEND ISSUED
March 1984
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
ALDRIN/DIELDRIN
CHLORDANE/HEPTACHLOR
CHLORDECONE
Kepone
DBCP
ODD (TDE)
DDT
DINITRAMINE
ENDRIN
o Oncogenicity
o Reductions in Non-target
and endangered species
o Oncogenicity
o Oncogenicity
o Mutagenicity
o Reproductive Effects
o Oncogenicity
o Oncogenicity
o Teratogenicity
o Reduction in En-
dangered Species
and Non-target
Species
o 39 FR 37246 (10/18/74");
(Cancellation of most uses).
o Notice of Intent to Cancel
39 FR 41298 (11/26/74).
(Cancellation of most uses),
o PD 1 published, 41 FR 12333
(3/25/76).
o PD 4 published, 42 FR 18885
(4/11/77).
o Notice of Intent to Cancel
42 FR 18885 (4/11/77).
o See listing under "RPAR's
COMPLETED".
O 36 FR 5254 (3/18/71);
(Cancelled).
o 37 FR 13369 (7/7/72);
(Cancellation of most uses),
o Notice of intent to Suspend
under Sec. 3(c)(2)(B)
issued on 9/28/82.
o See listing under "RPAR's
COMPLETED".
-------
NOTICE OF INTENT TO CANCEL/SUSPEND ISSUED Cont'd
March 1984
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
MIREX
2,4,5-T/SILVEX
o Oncogenicity
o Teratogenicity
o Fetotoxicity
41 FR 56703 (12/29/76);
(Most uses cancelled).
PD 1 published, 43 FR 17116
(4/21/78): 2,4,5-T - NTIS#
PB80-212665
Emergency Suspension Order and
Notice of Intent to Cancel pub-
lished, 44 FR 15874 (3/15/79):
2,4,5-T - NTIS# PB80-225923
Silvex - NTIS# PB80-226376
PD 4 published, 44 FR 72316
(12/13/79).
Cancellation Hearings began
3/14/80. The Agency is presently
negotiating with involved parties
to resolve the hearing.
-------
NOTICE OF INTENT TO REGISTER ISSUED
(Returned to the Registration Process)
March 1984
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
CACODYLIC ACID
AND SALTS
(PM-23)
CARBARYL
(PM-12)
o Oricogenicity
o Mutagenicity
o Teratogenicity
o Oncogenicity
o Mutagenicity
o Teratogenicity
Insufficient evidence to issue a
RPAR.
Decision document published 47 FR
20376 on 5/12/82. Returned to the
Registration process in 12/81
with the stipulation that pursuant
to FIFRA Section 3(c)(2)(B), data
on the rate of dermal absorption be
submitted, knapsack/hand sprayer
applicators treating ditch banks
and rights-of-way will wear
respirators or masks, and labels
recommend masks for homeusers
employing knapsacks or hand
sprayers.
Published 45 FR 81869 on 12/12/80.
The Agency has returned this com-
pound to the registration process
with the stipulation that the follow-
ing measures be considered: (1) a
FIFRA Section 3(c)(2)(B) action that
registrants remedy data limitations
identified in pre-RPAR review and
(2) appropriate label changes be
made to minimize exposure to Carbaryl,
Both measures are being considered
in the reregistration review of
this chemical.
10
-------
NOTICE OF INTENT TO REGISTER ISSUED
(Returned to the Registration Process)
March 1984
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
CHLOROFORM
Trichloro-
methane
(PM-16)
DICHLORVOS
DDVP
2 ,2-dichlorovinyl
dimethyl phosphate
(PM-15)
DIFLUBENZURON
Dimilin
(PM-17)
o Oncogenicity
o Oncogenicity
Mutagenicity
o Reproductive Effects
o Fetotoxicity
o Neurotoxicity
o Oncogenicity
o Hazard to Wildlife and
other Chronic Effects
PD 1 published 41 FR 14588 on
4/6/76; comment period closed
7/23/76.
FR Notice announcing termination
of this RPAR issued in December,
1982. The agency determined that
applicator exposure had been
reduced to a minimum as a result
of label amendments. Also regis-
trants were required to submit
data to establish tolerances of
permissible residues on raw
agricultural commodities.
Published 47 FR 45075 on 10/13/82.
NTIS f not available. Returned to
the registration process on 9/29/82,
stating that the Agency will reas-
sess carcinogenic potential and the
need for additional Oncogenicity
data upon completion of an in-progress
bioassay. Additional tests on
mutagenicity were required. Task
Force presently developing proto-
cols to initiate tests.
RPAR action completed in April 1979.
Registrant consented to restricted
uses. Decision Document was issued
9/30/82 and Agency concluded that
existing evidence does not support
issuance of an RPAR and consequently,
that an RPAR for Trichlorfon as a pre-
cursor of Dichlorvos, was not warranted,
11
-------
NOTICE OF INTENT TO REGISTER ISSUED
(Returned to the Registration Process)
March 1984
CHEMICAL
(Class of
Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
MALEIC HYDRAZIDE (MH)
(PM-25)
METHANEARSONATES
includes Amine
Methanearsenate,
Calcium Acid Meth-
anearsonate, Mono-
ammonium Methane-
arsonate (MAMA),
Monosodium Methane-
arsonate (MSMA),
Disodium Methane-
arsonate (DSMA)
(Special Review Br.
o Oncogenicity
o Mutagenicity
o Reproductive
Effects
o Oncogenicity
o Mutagenicity
o PD 1 published 42 FR 56920 on
10/28/77; comment period closed
12/14/77: NTIS# PB80 216740
o Decision document signed 6/28/82,
returning maleic hydrazide and salts
(K-MH, DEA-MH) to registration pro-
cess. Report #540/9-82-010; NTIS#
PB82-240300. FR Notice has been
combined with Chloroform (see
Chloroform).
o All required data has been submitted
to the Agency.
o Registrants decided not to per-
form similar tests on DEA-MH and
thus DEA-MH was suspended 11/81.
o On 6/28/83 the pre-RPAR review for
methanearsonate chemicals was
completed and a decision memo was
approved returning these chemicals
to the normal registration process.
The existing evidence was inadequate
to initiate an RPAR for the chemicals.
o 3(c)(2)(B) letter sent 9/26/83 requir-
ing a chronic feeding, Oncogenicity,
teratology, and applicator exposure
studies in order to determine if there
are any risk concerns.
12
-------
NOTICE OF INTENT TO REGISTER ISSUED
(Returned to the Registration Process)
March 1984
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
NALED
(PM-16)
10,10'Oxybisphen-
oxarsine (some uses)
(PM-22)
PARAQUAT
(PM-25)
PIPERONYL
(PM-17)
BUTOXIDE
o Mutagenicity
o Fetotoxicity
o Reproductive Effects
o
o
Arsenical Compound
suspected:
. Oncogenicity
. Mutagenicity
. Teratogenicity
Emergency Treatment
Chronic Effects
o Co-Carcinogenicity
o Carcinogenicity
o
o
Chemical returned to normal registra-
tion process on 6/30/83. Based on a re-
view of all available data, no valid
tests or definitive evidence exist which
meet or exceed the RPAR risk criteria.
However, per Registration Standard, addi-
tests have been required and due 6/86;
and will be reviewed to determine whether
there are any risks of concern.
Returned to the Registration
Process on April 9, 1979 based
on Memo indicating no evidence
of oncogenicity.
Decision document returning Paraquat
the registration process was signed
on 6/29/82. Published 47 FR 45075
on 10/23/82. NTIS # not available.
Decision Document outlines data gaps
and voluntary cancellation of certain
noncrop use sites.
Decision document complete.
Published 47 FR 20376 on 5/12/82.
NTIS# PB83-137901. Returned to the
registration process on 5/12/82.
Section 3(c)(2)(B) Notice requesting
additional data issued on 9/30/82.
Agency has received commitments from
certain registrants to conduct the
required studies.
13
-------
NOTICE OF INTENT TO REGISTER ISSUED
(Returned to the Registration Process)
Marcn 1984
CHEMICAL
(Class of Chemicals)
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE OF FEDERAL
REGISTER PUBLICATION
ROTENONE
(PM-17)
1081
(Fluoro-acetamide)
(PM-16)
TERBUTRYN
(PM-25)
TRIALLATE
(PM-25)
o Oncogenicity
o Mutagenicity
o Teratogenicity
o Reproductive Effects
o Chronic Toxicity
o Significant Wildlife
Populations Reductions
o Acute Toxicity to
Aquatic Wildlife
o Acute Toxicity to Mam-
malian and Avian Species
o Reduction in endangered
and noo target species
o Acute Toxicity without
antidote.
o Oncogenicity
o Mutagenicity
o Reproductive
Effects
Oncogenicity
Mutagenicity
Notice of Availability of De-
cision document published 46 FR
36745 on July 15, 1981. NTIS # not
available. Returned to Registra-
tion Process based on finding no
unreasonable adverse effects.
o PD 1 published 41 FR 52792 on
12/1/76: NTISt PB80-216823
o PD 2 published 45 FR 13189 on
2/28/80: NTISt.PB80-216831.
o Returned to registration pro-
cess with the restriction
that it be used only in sewers.
o PRE-RPAR evaluation completed.
o Returned to the Registration
Process. Registrants agreed
to change label to reduce
applicator risk to acceptable
levels. 47 FR 20376, published
5/12/82. NTIS # not available.
o Published 45 FR 82349 on 12/15/80,
NTIS # not available. The Agency
determined that, in light of the
low level of exposure, it should
be returned to the registration
process stipulating that a FIFRA
3(c)(2)(B) action be initiated
to obtain necessary toxicity data
to evaluate its hazards.
o 3(c)(2)(B) will be issued by 7/84
to include the data needs.
14
-------
NOTICE OF INTENT TO REGISTER ISSUED
(Returned to the Registration Process)
March 1984
CHEMICAL
(Class of Chemicals)
40C CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
DATE O
REGISTER PUBLICATION
S,S,S-TRIBUTY
PHOSPHOROTHRITHIOATE
(DEF)
(PM-25)
TRIBUTYL PHOSPHORO-
TRITHIOATE (Merphos)
(PM-25)
TRICHLORFON
(PM-16)
o Neurotoxicity
o Neurotoxicity
o Oncogenicity
o Mutagenicity
o Teratogenicity
o Fetotoxicity
o Reproductive Effects
o Pre-RPAR evaluation completed.
Returned to Registration Division
11/30/81, based on finding of no
potential unreasonable adverse
effects. Registrants agreed to
practice clothing requirement.
Published 47 FR 20376 on 5/12/82.
NTIS # not available.
o PRE-RPAR evaluation completed.
o Returned to Registration Divi-
sion, 11/30/81, based on finding
no potential unreasonable adverse
effects. Registrants agreed to
protective clothing requirement.
Published 47 FR 203765 on 25/12/82.
NTIS t not available.
o Removed from Pre-RPAR review as
it chemically relates to Dichlorvos.
See Dichlorvos.
o Registration Standard scheduled for
completion on 6/30/84. FR Notice
to be published on the issuance of
the Standard, thus concluding the
RPAR for review. Existing evidence
does not support issuance of an RPAR
for this chemical. On 9/30/83, similar
action was taken on DDVP, a metabolite
of Trichlorfon.
15
-------
RPARs COMPLETED
March 1984
CHEMICAL (Class of
Chemicals) and
RESPONSIBLE BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
AMITRAZ (Baam)
(PM-12)
o Oncogenicity
BENOMYL
(PM-21)
o Reduction in non-target
o Mutagenicity
o Teratogenicity
o Reproductive Effects
o Hazard to Wildlife
o
o
PD 1 published 42 PR 18299 on
4/6/77; comment period closed
7/18/77: NTIS# PB80-212046.
PD 2/3 completed and Notice of
Determination published 44 FR 2678
on 1/12/79; comment period closed
2/12/79: NTIS# PB80-211436.
PD 4 published 44 FR 32736 on
6/7/79; 44 FR 59938 on 10/7/79
(correction): NTISt PB80-211428.
. conditional registration approved
for pears but not for apples.
. registrants submitted an oncogen-
icity study in 1/84 and will
collect additional benefits data.
. tolerance for pears approved 12/6/79.
PD 1 published 42 FR 61788 on 12/6/77.
PD 2/3 completed and Notice of
Determination published 44 FR 51166
on 8/30/79: comment period closed
9/28/79.
PD 4 completed and Notice of
Determination published 47 FR 46747
on 10/20/82. NTIS# PB83-148189.
The Notice requires use of either cloth
or commercially available disposable
dust masks by mixer/loaders of benomyl
intended for aerial application and
that registrants of benomyl products
conduct field monitoring studies to
identify residues that may enter
aquatic sites after use on rice.
16
-------
RPARs COMPLETED - Cont'd
March 1984
CHEMICAL (Class of
Chemicals) and
RESPONSIBLE BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
BENOMYL (cont'd)
(PM 21)
CHLOROBENZILATE
(PM-12)
o
o
Oncogenicity
Testicular Effects
DBCP
1,2-dibromo-
3-chloropropane
(PM-21)
o
o
Oncogenicity
Reproductive Effects
o 3(C)(2)(B) letter issued 3/83.
Registrant presently conducting
field monitoring study.
o PD 1 published 41 FR 21517 on
5/26/76; comment period closed
7/28/76.
o PD 2/3 and Notice of Proposed Deter-
mination published 43 FR 29824
on 7/11/78; comment period closed
8/10/78: NTISf PB80-213887
o Final Determination based on PD 2/3
published 43 FR 29824 on 7/11/78).
o PD 4 and Notice of Intent to Cancel
published 44 FR 9547 on 2/13/79:
NTISf PB80-213929
o PD 1 published 42 FR 48026 on
9/22/77; comment period closed
11/7/77.
o Suspension Order and Notice of Intent
to Cancel published 42 FR 57543 on
11/3/77.
o Amended Notice of Intent to Cancel
and PD 2/3/4/ published 43 FR 40911
on 9/13/78: NTIS# PB80-213853
o Notice of Intent to Suspend All Pro-
ducts Issued published 44 FR 41783
on 7/18/79.
o Suspension Order (affecting all uses
except pineapple) and Notice of Intent
to Cancel All Uses published 44 FR
65135 on 10/29/79.
17
-------
RPARs COMPLETED - Cont'd
March 1984
CHEMICAL (Class of
Chemicals) and
RESPONSIBLE BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
DBCP (cont'd)
(PM-21)
DIALLATE
(PM-25)
DIMETHOATE
(PM-16)
o
o
Oncogenicity
Reproductive Effects
o
o
Oncogenicity
Mutagenicity
o Oncogenicity
o Mutagenicity
o Fetotoxicity
o Reproductive effects
o Agreement reached with registrants
that all uses, except on pineapples,
are cancelled.
o Proposed Intent to Cancel DBCP Use on
Pineapples published in 49 FR 1556 on
1/12/84. Final Notice is being
drafted.
PD 1 published 42 FR 27669 on 5/31/77;
comment period closed 9/9/77: NTIS#
PB80-212863.
PD 2/3 completed and Notice of
Determination published 45 FR
38437 on 6/9/80; comment period
closed 7/9/80: NTIS# PB80 216849:
PD 4 completed and announced in
Federal Register, 47 FR 27109
(6/23/82). NTIS # not available.
Classifies current products for
restricted use by certified
applicators wearing protective
clothing.
o
o
PD 1 published 42 FR 45806 on
9/22/77; comment period closed
1/6/78.
PD 2/3 completed and Notice of
Determination published 44 FR
66558 on 11/19/79; comment period
closed 12/19/79: NTIS# PB80-213846.
PD 4 published 46 FR 5334 on 1/19/81.
NTIS t not available. Registration
Standard approved and signed 3/31/83.
18
-------
RPARs COMPLETED - Cont'd
March 1984
CHEMICAL (Class of
Chemicals) and
RESPONSIBLE BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
EBDC's
Ethylenebis-
dithiocarbamates,
maneb, mancozeb,
metiram, nabam,
zinab, amoban,
(PM-21)
ENDRIN
(PM-15)
o
o
Oncogenicity
Teratogenicity
Hazard to Wildlife
o
o
o
Oncogenicity
Teratogenicity
Reduction in en-
dangered species and
nontarget species
o
PD 1 published 42 FR 40618 on
8/10/77; comment period closed
12/23/77.
Decision Document and Final
Determination published 47 FR
47669 on 10/27/82. NT-IS # not
available. The Notice returned
EBDC products to the Registration
Process on condition that certain
use precautions are added to the
product labels and registrants
agree to generate additional
toxicology data.
Data Call-in Notices requesting
registrants to generate the
needed data on 6 EBDC's and
ETU have been issued.
Registrants committed to generate
data for all chemicals except
Amobam. (See page 44.)
PD 1 published 41 FR 31316 on
7/26/76; comment period closed
11/4/76: NTIS# PB81-112690.
PD 2/3 completed and Notice of
Proposed Determination published
43 FR 51132 on 11/2/78.
PD 4 published (including can-
cellations) 44 FR 43631 on 7/25/79:
NTIS# PB81-10980.
A revised Notice of Intent to Cancel
being drafted and will be available
for comments prior to final issuance
19
-------
RPARS COMPLETED - Cont'd
March 1984
CHEMICAL (Class of
Chemicals) and
RESPONSIBLE BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
ENDRIN cont'd
(PM-15)
EPN
(PM
12)
o Oncogenicity
o Teratogenicity
o Reduction in en-
dangered species and
nontarget species
o Neurotoxicity
ETHYLENE DIBROMIDE
(EDB)
(Special Review Br.)
o Oncogenicity
o Mutagenicity
o Reproductive Effects
PD 4 follow-up notice mailed
8/28/80, cancellations began
30 days later.
Some uses are conditionally
registered because require-
ments have been met.
PD 1 published 44 FR 54384 on
9/19/79? comment period closed
12/29/79: NTISt PB80-216815.
Final Notice of Determination and
Decision Document forwarded to
Acting AA on 6/30/83.
Final Notice of Determination
signed by Acting AA on 6/30/83
and published 48 FR 39494 on
8/31/83.
PD 1 published 42 FR 63134 on
12/14/77? comment period closed
4/3/78: NTIS# PB80-109456.
PD 2/3 completed and Notice of
Determination published, 45 FR
81586 on 12/10/81; comment period
closed 3/9/81.
PD 4 and FR Notice were approved on
9/28/83. Emergency suspension of
soil fumigation uses and cancella-
tion of others published 48 PR
46228 on 10/11/83.
20
-------
RPARs COMPLETED - Cont'd
March 1984
CHEMICAL (Class of
Chemicals) and
RESPONSIBLE BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
ETHYLENE DIBROMIDE
(EDB) (cont'd)
(Special Review Br.)
GOAL
(PM-25)
LINDANE
(Special Review Br.)
o Oncogenicity
o Mutagenicity
o Reproductive
Effects
o Oncogenicity
o Oncogenicity
o Teratogenicity
o Reproductive Effects
o Acute Toxicity
o Other Chronic Effects
Emergency Suspension on uses
to fumigate grain and grain
milling equipment published
49 FR 4452 on 2/6/84.
Proposed tolerances for EDB
in grains published 49 FR
56 on 2/22/84.
Proposed tolerances for EDB
in citrus and papayas pub-
lished 49 FR 806 on 3/6/84.
Final tolerances for EDB in
grains published 49 FR 17144
on 4/23/84.
PD 1/2/3 completed. NTISI PB82
172289.
PD 4 published 47 FR 27118 on
6/23/82: NTISf PB82-185133.
The decision is to continue use
of the herbicide subject to
certain restrictions (on PCE)
pertaining to formulation of
the product.
PD 1 published 42 FR 9816 on
2/18/77; comment period closed
6/20/77: NTISf PB80-213911
PD 2/3 completed and Notice of
Determination published 45 FR
45362 on 7/3/80; comment period
closed 9/15/80.
21
-------
RPARS COMPLETED - Cont'd
Marcn 1984
CHEMICAL (Class of
Cneraicals) and
RESPONSIBLE BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
LINDANE (cont'd)
(Special Review Br,
o Oncogenicity
o Teratogenicity
o Reproductive Effects
o Acute Toxicity
o Otner Chronic Effect
PCNB
Pentachloro-
nitrobenzene
(PM-21)
o Oncogenicity
PRONAMIDE
(PM-25)
o Oncogenicity
o
o
PD 4 and decision package were
on 9/30/83. Notice published 48 FR
48512-48522 on 10/19/83. The deci-
sion cancels the indoor use of smoke
fumigation devices and the use of
dog dips to treat pests other than
mites. All other uses will continue
with use restrictions and label modi-
fications.
Hearings were requested by regis-
trants for indoor smoke fumigation
devices and dog dips.
PD 1 published 42 FR 61894 on
10/13/77; comment period closed
2/6/78: NTIS fPB80-216799.
PD 2/3 in Agency review.
RPAR terminated through negotiated
agreement with registrants to
reduce levels of the HCB contami-
nant and to make lable changes to
reduce exposure. Published 47 FR
18177 on 4/19/82.
PD 1 published 42 FR 32302 on
5/20/77; comment period closed
8/29/77: NTIS #PB81 109472.
PD 2/3 completed and Notice of
Proposed Determination published
44 FR 3083 on 1/15/79; comment
period closed 2/14/79: NTIS
IPB80-213911.
22
-------
RPARs COMPLETED - Cont'd
March 1984
CHEMICAL (Class of
Chemicals) and
RESPONSIBLE BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
PRONAMIDE (cont'd)
(PM-25)
o Oncogenicity
STRYCHNINE/
STRYCHNINE SULFATE
(Special Review Br.)
Reduction in Non-target
and Endangered Species
PD 4 completed and Final Determina-
tion published 44 FR 61640 on
10/26/79: NTIS # PB81-112716. The
following actions were taken: Can-
cellation of registrations of
products allowing hand spray appli-
cations, except for use on ornamen-
tals and nursery stock; cancellation
of registrations of products unless
the registrant modifies the terms
and conditions to allow certain uses
of wettable powder products only by
or under direct supervision of cer-
tified applicators; modification of
labeling of wettable powder products
to include specific general precau-
tions, directions as to protective
clothing to be worn, dilution in-
structions for wettable powder
products, and watering instructions
for granular products used on turf;
and Agency revision of the lettuce
tolerance from 2 ppm to Ippiti from
required residue data that was
submitted.
PD 1 published 42 FR 2713 on
1/13/77; comment period closed
3/15/77: NTISf PB80-216807.
PD 2/3 completed and Notice of
Determination published 45 FR
73602 on 11/5/80; comment period
closed 9/30/81: NTISt PB81-123960.
23
-------
RPARs COMPLETED - Cont'd
March 1984
CHEMICALS (Class of
Chemicals) and
RESPONSIBLE BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
STRYCHNINE (cont'd)
STRYCHNINE SULFATE
(Special Review Br.)
THIOPHANATE METHYL
(PM-21)
TOXAPHENE
(PM-12)
o
o
o
o
Reduction in non-target
and Endangered Species
Mutagenicity
Reduction in Non-
target Species
(Rebutted)
Oncogenicity
Population reduction
non-target animal species
Acute toxicity to
aquatic organisms
Chronic effects to
wildlife
o
o
PD 4 and decision package were
approved on 9/30/83. Published 48
FR 48522 on 10/19/83. Decision
cancels use of strychnine for
control of prairie dogs and several
other rodents and small mammals.
All other uses will require label
modifications.
PD 1 published 42 FR 61940 on
12/7/77; comment period closed
3/27/78: NTIS #PB80-216856.
PD 2 completed and Notice of
Proposed Determination pub-
lished 44 FR 58798 on 10/11/79.
PD 4 completed and Notice of
Determination published 47 FR
46747 on 10/20/82. NTIS f not
available.
PD 1 published 42 FR 26860 on
5/27/77; comment period closed
9/13/77; NTISf PB80-216732.
Decision Document published 11/29/83,
Final Notice of Determination
published in 47 FR 53784 on 11/29/82
NTIS* PB83-144204.
24
-------
RPARs COMPLETED - Cont'd
March 1984
CHMEICAL (Class of
Chemicals) and
RESPONSIBLE BRANCH
40 CFR 162.11 CRITERIA
POSSIBLY MET OR EXCEEDED
CURRENT
STATUS
TOXAPHENE (cont'd)
(PM-12)
2,4,5-T/SILVEX
(PM-22/23)
TRIFLURALIN
(Treflan)
(PM-23)
o Oncogenicity
o Population reduction
non-target animal species
o Acute toxicity to
aquatic organisms
o Chronic effects to
wildlife
o Oncogenicity
o Teratogenicity
o Fetotoxicity
o Oncogenicity
o Mutagenicity
Notice presented the Agency deci-
sion to cancel registrations for
most uses and continue registra-
tion of certain uses under specific
specific terms and conditions. The
continued uses are: corn, cotton,
and small grain for specific insect
infestation (emergency use only),
pineapples and bananas for specific
insects in Puerto Rico and the
Virgin Islands only, and scabies
treatments of cattle and sheep.
PD 4 completed and Final Deter-
mination published 44 FR 72316 on
12/13/79; applies to uses not
included in suspension actions
described in prior section under
"Notice of Intent to Cancel/
Suspend Issued".
PD 1/2/3/ published 44 FR 50911
on 8/30/79; comment period closed
11/13/79: NTIS# PB80-213937.
PD 4 published 47 FR 33777 on
8/4/82: Report 1540/9-82-011;
NTIS# PB82-263252.
Trifluralin registrations allowed
to continue if the total N-nitro-
samine contamination is kept below
0.5 ppm for tecnnical products and
below a figure based on Trifluralin
content for formulated products.
25
-------
REGISTRATION STANDARDS DEVELOPMENT - DATA COLLECTION
March 1984
CHEMICAL (Class
of Chemicals)
RESPONSIBLE
RD BRANCH/PM
TYPE OF
CHEMICAL
AMITRAZ
BTC 2125
CAPTAN
COPPER SULFATE & related hydrates
CYHEXATIN
3,5-Dibromosalicylanilide
DIFLUBENZURON
DIPROPETRYN
EPN
GLYPHOSATE
HCL
HEXYLENE GLYCOL
HYAMINE 3500
METRIBUZIN
MONOCROTOPHOS
I-R Brancft/PM-12
Disinfectants Br./PM-31
H-F Brancn/PM-21
H-F Brancn/PM-21
I-R Branch/PM-12
Disinfectants Br./PM~32
I-R Branch/PM-17
H-F Branch/PM-25
I-R Brancn/PM-12
H-F Brancn/PM-25
Disinfectants Br./PM-32
Disinfectants Br./PM-31
Disinfectants Branch/PM-31
H-F Brancn/PM-25
I-R Branch/PM-16
Insecticide
Disinfectant
Fungicide
Fungicide
Insecticide
Disinfectant
Insecticide
Herbicide
Insecticide
Herbicide
Disinfectant
Disinfectant
Disinfectant
Herbicide
Insecticide
26
-------
REGISTRATION STANDARDS DEVELOPMENT - DATA COLLECTION
March 1984
CHEMICAL (Class
of Chemicals
RESPONSIBLE
RD BRANCH/PM
TYPE OF
CHEMICAL
NAPTALAM
NEOMYCIN SULFATE
NITRAPYRIN
OMADINE-SODIUM
ORYZALIN
PARATHION
POTASSIUM & SODIUM HYDROXIDE
POTASSIUM PERMANGANATE
SODIUM BISULFATE
SULFURYL FLUORIDE
TCC
THIOPHANATE Ethyl
THIOPHANATE Methyl
H-F Branch/PM-25
H-F Branch/PM-21
H-F Branch/PM-23
Disinfectants Br./PM-31
H-F Branch/PM-25
I-R Branch/PM-12
Disinfectants Br./PM-32
H-F Branch/PM-23
Disinfectants Br./PM-32
I-R Branch/PM-16
Disinfectants Br./PM-32
H-F Branch/PM-21
H-F Branch/PM-21
Herbicide
Fungicide
Herbicide
Disinfectant
Herbicide
Insecticide
Disinfectant
Herbicide
Disinfectant
Insecticide
Disinfectant
Fungicide
Fungicide
27
-------
REGISTRATION STANDARDS DEVELOPMENT - DATA EVALUATION AND March 1984
DEVELOPMENT OF REGULATORY POSITION
CHEMICAL (Class
of Chemicals)
RESPONSIBLE
RD Branch/PM
TYPE OF
CHEMICAL
ACEPHATE
ALACHLOR
ALDICARB
ARSENICALS
BENOMYL
BENTAZON(Na)(Basagram)
CAPTAFOL
CARBARYL
CARBOFENOTHION
CARBOFURAN
CHLORDIMEFORM/HCL
CHLOROBENZILATE
CHLOROTHALONIL
CHLORPYRIFOS
CYANAZINE
DAMINOZIDE(Alar)
DEMETON
I-R Branch/PM-16
H-F Branch/PM-25
I-R Branch/PM-12
H-F Branch/PM-21
H-F Branch/PM-21
H-F Branch/PM-25
H-F Branch/PM-21
I-R Branch/PM-12
I-R Branch/PM-16
I-R Branch/PM-12
I-R Branch/PM-12
I-R Branch/PM-12
H-F Branch/PM-21
I-R Branch/PM-12
H-F Branch/PM-25
H-F Branch/PM-25
I-R Branch/PM-16
Insecticide
Herbicide
Insecticide
Fungicide
Fungicide
Herbicide
Fungicide
Insecticide
Insecticide
Insecticide
Insecticide
Insecticide
Herbicide
Insecticide
Herbicide
Herbicide
Insecticide
28
-------
REGISTRATION STANDARDS DEVELOPMENT - DATA EVALUATION AND March 1984
DEVELOPMENT OF REGULATORY POSITION
CHEMICAL (Class
of Chemicals)
RESPONSIBLE
RD BRANCH/PM
TYPE OF
CHEMICAL
DICOFOL
DISULFOTON
FENSULFOTHION
FLUCHLORALIN (Basalin)
FONOFOS
HELIOTHIS
LINURON
NORFLURAZON
PENDIMETHALIN (Prowl)
PHORATE
PICLORAM
POTASSIUM Bifluoride
POTASSIUM BROMIDE
POTASSIUM IODATE
PROPACHLOR
TEBUTHIURON
THIRAM
I-R Branch/PM-12
I-R Branch/PM-15
I-R Branch/PM-15
H-F-Branch/PM-25
I-R Branch/PM-16
I-R Branch/PM-17
H-F Branch/PM-25
H-F Branch/PM-23
H-F Branch/PM-25
I-R Branch/PM-16
SR Branch
Disinfectants Br./PM-32
Disinfectants Br./PM~32
Disinfectants Br./PM-32
H-F Branch/PM-25
H-F Branch/PM-25
H-F Branch/PM-21
Insecticide
Insecticide
Insecticide
Herbicide
Insecticide
Insecticide
Herbicide
Herbicide
Herbicide
Insecticide
Herbicide
Disinfectant
Disinfectant
Disinfectant
Herbicide
Herbicide
Fungicide
29
-------
REGISTRATION STANDARDS DEVELOPMENT - DATA EVALUATION AND March 1984
DEVELOPMENT OF REGULATORY POSITION
CHEMICAL (ClassRESPONSIBLETYPE OF
of Chemicals) RD BRANCH/PM CHEMICAL
TPTH(Triphenyltin Hydroxide) H-F Branch/PM-21 Fungicide
TRICHLORFON I-R Branch/PM-16 Insecticide
30
-------
REGISTRATION STANDARDS - ISSUED
March 1984
CHEMICAL & REPONSIBLE TYPE OF DATE OF DATE OF GUIDANCE
PRODUCT MANAGER (PM) IN CHEMICAL STANDARD PACKAGE &
REGISTRATION DIVISION & NTIS NOS. NTIS NOS.
ALDICARB
(PM 12)
ALIETTE
(PM 22)
Insecticide March 30, 1984 3/30/84
Fungicide June 30, 1983* 6/30/83*
ALUMINUM PHOSPHIDE
(PM 16)
4-AMINOPYRIDINE (AVITROL)
(PM 16)
AMITROLE
(PM 25)
AMMONIUM SULFAMATE
(PM 25)
Insecticide
Bird Chemosterilants
Toxicants and
Repellents
Herbicide
Herbicide
October 1981 11/24/81
NTISt PB82-137514 RS-81-017
September 1980*
March 30, 1984
9/30/80
RS 81-0003
3/30/84
June 1981 8/5/81
NTIS# PB82-133570 RS-81-012
ANILAZINE
(PM 21)
ASPON
(PM 16)
ATRAZINE
(PM 25)
Herbicide
Insecticide
Herbicide
December 13, 1983 12/13/83
September 1980 9/30/80
NTIS# PB81-112484
September 30, 1983*
* NTIS PB number not available.
31
-------
REGISTRATION STANDARDS
ISSUED
Marcn 1984
CHEMICAL & REPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
BARIUM METABORATE
(PM 22)
BIFENOX
(PM 25)
BKLFI-2
(PM 32)
BOLSTAR (SULPROFOS)
(PM 12)
TYPE OF
CHEMICAL
Fungicide
Herbicide
Disinfectant
Insecticide
DATE OF
STANDARD
& NTIS NOS.
April 14, 1983*
June 1981*
December 1981*
August 1981
NTISf PB82-133646
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
6/27/83*
8/12/81
RS-82-007
12/29/81
RS-82-002
8/10/81
RS-81-008
BORIC ACID (pending 25(b)
(PM 16)
BROMACIL & SALTS
(PM 25)
BUTYLATE
(PM 25)
CARBARYL
(PM 12)
CARBOXIN (VITAVAX*)
(PM 21)
exemption decision)
Herbicide
Herbicide
Insecticide
Fungicide
September 1982* 9/30/82*
September 30, 1983*
March 30, 1984 3/30/84
August 1981 8/12/81
NTISf PB82-132994 RS-81-007
* NTIS PB number not available.
32
-------
REGISTRATION STANDARDS - ISSUED Cont'd
Marcn 1984
CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
TYPE OF
CHEMICAL
DATE OF
STANDARD
& NTIS NOS.
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
CHLORAMBEN
(PM 25)
CHLOROBENZILATE
(PM 12.)
CHLORONEB
(PM 21)
CHLOROPICRIN
(PM'21)
COUMAPHOS
(PM 15)
CRYOLITE
(PM 17)
CYCLOHEXIMIDE
(PM 21)
DCNA
(PM 21)
DEET
(PM 25)
Herbicide
Insecticide
Fungicide
Insecticide
Insecticide
Insecticide
Fungicide
Herbicide
Insecticide
August 1981
NTISf PB82-134347
8/12/81
RS-81-015
December 30, 1983 12/20/83
September 1980 9/30/80
NTISf PB81-123804
September 1982*
9/28/82*
August 1981 9/4/81
NTIS# PB82-133570 RS-81-013
June 23, 1983*
September 1982*
June 28, 1983*
9/24/82*
September 14, 1983 12/14/83
December 1980
12/2/80*
RS-81-004
* NTIS PB number not available.
33
-------
REGISTRATION STANDARDS - ISSUED Cont'd
March 1984
CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
DIALIFOR
(PM 16)
DIALLATE
(PM 25)
DICAMBA
(PM 25)
DICHLONE
(PM 21)
DICOFOL
(PM 12)
DICROTOPHOS (BIDRIN*)
(PM 16)
DIMETHOATE
(PM 16)
DIOXATHION
(PM 15)
DIURON
(PM 25)
TYPE OF
CHEMICAL
Insecticide
Herbicide
Herbicide
Fungicide
Insecticide
Insecticide
Insecticide
Insecticide
Herbicide
DATE OF
STANDARD
& NTIS NOS.
July 1981
NTISf PB82-133638
March 31, 1983*
September 30, 1983*
March 1981
NTISf PB82-131418
December 30, 1983
April 198:2
NTISf PB82-204383
March 31, 1983*
March 31, 1983*
September 28, 1983*
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
7/31/81
RS-81-014
4/7/83*
3/16/81
RS-81-001
12/30/83
6/30/82
4/11/83*
4/7/83*
* NTIS PB number not available
34
-------
REGISTRATION STANDARDS - ISSUED Cont'd
March 1983
CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
ENDOSULPAN
(PM 15)
EPTC
(PM 25)
ETHION
(PM 16)
ETHOPROP
(PM 16)
TYPE OF
CHEMICAL
Insecticide
Herbicide
Insecticide
Nematicide
DATE OF
STANDARD
& NTIS NOS.
March 1982
NTISi PB82-243999
September 30, 1983*
December 1982*
June 23, 1983*
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
6/25/82
RS82-0081
12/23/82*
6/24/83*
ETHOXYQUIN
(PM 25)
2 ETHYL 1,3 HEXANEDIOL(6-12)
(PM 17)
FENAMINOSULF
(PM 21)
FENSULFOTHION
(PM 15)
FORMETENATE HYDROCHLORIDE
(PM 12)
Growth Regulator
Insecticide
Fungicide
Insecticide
Insecticide
March 1981*
3/81
RS-81-011*
June 1981 6/5/81
NTISt PB81-234098 RS-81-005
September 30, 1983*
December 22, 1983* 12/22/83*
September 16, 1983* 9/23/83'
* NTIS PB number not available.
35
-------
REGISTRATION STANDARDS - ISSUED Cont'd
Marcn 1984
CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
TYPE OF
CHEMICAL
DATE OP
STANDARD
& NTIS NOS.
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
FUMARIN (COUMAFURYL)
(PM 16)
GLEAN® (CHLORSULFURON)
(PM 25)
HEXAZINONE (VELPAR)
(PM 23)
HYPOCHLORITE Salts
(PM-32)
ISOPROPALIN
(PM 25)
MAGNESIUM PHOSPHIDE
(PM 16)
MCPA
(PM 23)
METALAXYL (RIDOMIL*)
(PM 21)
METHAMIDOPHOS (MONITOR*)
(PM 16)
Rodent Toxicant
and Anticoagulant
Herbicide
Herbicide
Disinfectant
Herbicide
Insecticide
Herbicide
Fungicide
Insecticide
September 1982
NTISf PB81-123812
September 1982*
February 1982*
January 13, 1983
August 1981
NTISt PB82-131293
Marcn 1982
NTISI PB82-195777
Marcn 1982*
August 1981
NTISI PB82-172297
September 1982*
10/21/80
9/30/82*
4/27/82*
8/5/81
RS-81-009
3/29/82
RS-82-006
6/30/82*
8/31/81
RS-82-005
9/24/82*
* NTIS PB number not available.
36
-------
REGISTRATION STANDARDS - ISSUED Cont'd
March 1984
CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
TYPE OF
CHEMICAL
DATE OF
STANDARD
& NTIS NOS.
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
METHIDATHION
(PM 12)
METHOMYL
(PM 12)
METHOPRENE
(PM 17)
METOLACHLOR
(PM 23)
MONURON
(PM 25)
MONURON TCA
(PM 25)
NALED
(PM 16)
NAPHTHALENE
(PM 16)
NAPHTHALENEACETIC ACID
AND ITS SALTS
(PM 25)
Insecticide
Insecticide
Insecticide
Herbicide
Herbicide
Herbicide
Inseticide
Insecticide
Growth Regulator
January 13, 1983
February 1982*
June 30, 1983*
June 30, 1983*
June 30, 1983*
1/14/83
September 1981 1/22/82
NTIS* PB82-180738 RS-82-001
3/31/82*
September 1980* 9/30/80*
NTIS* PB81-123820
7/7/83*
7/7/83*
7/6/831
September 1981 11/9/81
NTIS* PB82-139437 RS-81-016
August 1981 8/18/81
NTIS #PB82-131145 RS-81-006
* NTIS PB number not available.
37
-------
REGISTRATION STANDARDS - ISSUED Cont'd
March 1984
CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
OBPA (10, 10'-
OXYBISPHENOXARSINE)
(PM 21)
PHOSALONE
(PM 12)
PLANTPIN® (BQTOXICARBOXIME)
(PM 12)
SIMAZINE
(PM 23)
SULFUR
(PM 22)
SULPROFOS (BOLSTAR)
(PM 12)
TEMEPHOS (ABATE)
(PM 16)
TERBACIL
(PM 25)
TERBUFOS
(PM 16)
TYPE OF
CHEMICAL
Fungicide
Insecticide
Insecticide
Herbicide
Fungicide
Insecticide
Insecticide
Herbicide
Insecticide
DATE OF
STANDARD
& NTIS NOS.
September 1981
NTIS# PB82-172271
September 1981
NTISf PB82-131731
September 1981
NTIS# PB82-177585
March 30, 1984
December 1982*
August 1981
NTISt PB82-133646
August 1981
NTISf PB82-140641
June 4, 1982*
June 30, 1983*
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
10/27/81
RS-82-003
9/18/81
RS-81-010*
9/30/81
RS-82-004
3/30/84
12/29/82*
8/10/81
RS-81-008
9/25/81
RS-81-018
6/4/82*
6/30/83*
* NTIS PB number not available.
38
-------
REGISTRATION STANDARDS - ISSUED Cont'd
Marcn 1984
CHEMICAL & RESPONSIBLE
PRODUCT MANAGER (PM) IN
REGISTRATION DIVISION
TYPE OF
CHEMICAL
DATE OF
STANDARD
& NTIS NOS.
DATE OF GUIDANCE
PACKAGE &
NTIS NOS.
TERRAZOLE
(PM 21)
Fungicide
September 1980
NTIS# PB81-126716
9/30/80
OPP-80-525
WARFARIN
(PM 16)
Rodent Toxicant &
Anticoagulant
August 1981 10/26/81
NTIS# PB82-140716 RS-81-019
ZINC PHOSPHIDE
(PM 16)
Rodent Toxicant and
Anticoagulant
June 1982*
6/23/82*
* NTIS PB number not available.
39
-------
March 1984
DATA CALL-IN - STATUS OF CHEMICALS
The following chemical clusters are being processed through Data Call-in (DCI).
These clusters are the same as described in the Federal Register notice on
November 14, 1980 (45 FR 75488), except that the chemicals now in Registration Standard
development or in the RPAR process are omitted. The status of these clusters and the
chemicals are as follows.
o Data Call-in Cluster #1 consists of insecticides used on corn, alfalfa and sorghum (1-2)
Chemical Status
Bufencarb Decision reached - cancelled/suspended.
Carbofuran Decision reached - chronic data base complete.
Carbophenothion Decision reached - chronic data being generated.
Chlorpyrifos Decision reached - chronic data base complete.
Disulfoton Decision reached - chronic data being generated.
Ethoprop Decision reached - chronic data base complete.
Fensulfothion Decision reached - chronic data being generated
Fonofos Decision reached - chronic data being generated
Landrin (Broot) Decision reached - chronic data being generated.
Phorate Decision reached - chronic data being generated.
TEPP Decision reached - suspended/cancelled
Terbufos Decision reached - no added data required.
Trichlorfon Decision reached - chronic data base complete.
"Letter being drafted": The Agency is investigating the available chronic studies and
discussing the findings with registrants.
"Letter issued (date)": The notice/notification or equivalent was issued to indicate
existing chronic data gaps.
"Decision reached": The Agency has evaluated all the responses from registrants reques-
ting exemptions, waivers, commitments, offers to cost share, cancellations, suspensions,
etc. and has issued final decisions on the data required and status of all registrations
containing the chemical. The terms "chronic data being generated" or "chronic data
waiver or deferral" are self explanatory. "Chronic data base complete" may mean that the
data were available, recently submitted, or certain data requirements have been waived.
The terms "cancelled", "suspended", "no current registrations" mean that there are no
known active registrations of the chemicals. The term "Defer requirements to Standard"
means that the standard is planned to be developed within two years hence and the chronic
requirements will be addressed in the standard.
40
-------
March 1984
DATA CALL-IN - STATUS OF CHEMICALS cont'd
o Data Call-in Cluster #2 consists of insecticides used on citrus and grapes (1-4).
Chemical Status
Chlorobenzilate
Cryolite
Dimethoate
Dioxothion
Ethion
Forraetanate hydrochloride
Naled
Tetradifon
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
reached
reached
reached
reached
reached
reached
reached
reached
o Data Call-in Cluster #3 consists of insecticides
wheat and tobacco (1-1).
Aldicarb
Bollex
Chlordimeform
Chlordiraeform hydrochloride
Demeton
Dimilin
Endrin
Fenvalerate
Gossyplure
Grandlure
Heliothis virus
Methyl Parathion
Monocrotophos
Parathion
Permethrin
Phospharaidon
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
reached -
reached -
reached -
reached -
reached -
reached -
reached -
reached -
reached -
reached -
reached -
reached -
reached -
reached -
reached -
reached -
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
chronic
data
data
data
data
data
data
data
data
data
data
data
data
data
data
data
data
chronic data being generated.
chronic data deferred.
chronic data base being generated,
chronic data deferred.
• chronic data being generated.
chronic data deferred.
• chronic data being generated.
suspended/cancelled.
used on cotton, soybeans, peanuts,
base complete.
base complete.
base complete.
base complete.
being generated.
base complete.
base complete.
base complete.
base complete.
base complete.
base complete.
being generated.
base complete.
being generated.
base complete.
being generated.
41
-------
March 1984
DATA CALL-IN - STATUS OF CHEMICALS COnt'd
o Data Call-in Cluster #4 consists of herbicides used on corn (H-2).
Chemical Status
Alachlor
Atrazine
Butylate
Cyanazine
Cyprazine
Dicamba
EPTC
Simazine
TCBC
Decision reached - chronic data base complete.
Decision reached - chronic data deferred.
Decision reached - chronic data being generated.
Decision reached - chronic data deferred.
Decision reached - Suspension/Cancellation.
Decision reached - chronic data deferred.
Decision reached - chronic data being generated.
Decision reached - chronic data deferred.
Decision reached - cancelled/suspended.
Data Call-in Cluster #5 consists of herbicides used on soybeans, cotton, peanuts and
alfalfa (H-3).
Acifluorfen
Bentazon (and sodium form)
2,4-DB
Dichlofop methyl
Dinitramine
Dipropetryn
DSMA
EGT
Fluchloralin
Glyphosate isopropylamine salt
Metribuzin
Naptalam
Nitralin
Norflurazon
Oryzalin
Oxyfluoren
Pendimethalin
Perfluidone
Profluralin
Pronamide
Propachlor
Vernolate
Decision reached - chronic data base complete.
Decision reached - chronic data base complete.
Decision reached - chronic data being generated.
Decision reached - chronic data base complete.
Decision reached - suspended.
Letter issued 11/16/83.
Letter issued 9/26/83.
Decision reached - cancelled.
chronic data being generated.
chronic data basegcomplete.
chronic data base complete.
Defer requirements to standard
cancelled.
Letter issued 7/25/83.
Decision reached - chronic data base complete.
chronic data base complete.
chronic data base complete.
No added data required.
cancelled.
chronic data being generated.
Letter issued 1/19/83
Decision reached - chronic data being generated.
Decision reached
Decision reached
Decision reached
Decision reached
Decision reached
Decision reached
Decision reached
Decision reached
Decision reached
Decision reached
42
-------
DATA CALL-IN - STATUS OF CHEMICALS cont'd
o Data Call-in Cluster #6 consists of fungicides used on vegetables (F-3).
Chemical Status
Marcn 1984
Anilazine
Calcium Cyanamide
DCNA
Hexachlorophene
Triadimefon
Decision reached - Defer requirements to standard.
Letter issued 8/11/83.
Decision reached - Defer requirements to standard.
Decision reached - Defer requirements to standard.
Decision reached - chronic data base complete.
o Special Data Call-in Fungicide Project consists of certain large volume fungicides which
will be processed through DCI and subject to comparative risk analysis.
Captafol
Chlorothalonil
Copper (Bordeaux mixture)
Copper Carbonate
Copper Naphthenate
Copper Oxide
Copper Oxychloride
Copper Quinolinolate
Copper Sulfate Basic
Copper Sulfate Monohydrate
Dinocap
Dodine
Ferbam
Folpet
Thiram
Decision reached - chronic
Decision reached - chronic
Decision feached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Decision reached - chronic
Letter issued 9/4/81.
Letter issued 9/4/81.
Decision reached - chronic
data being generated,
data base complete.
data not applicable.
data not applicable.
data not applicable.
data not applicable.
data not applicable.
data not applicable.
data not applicable.
data not applicable.
data being generated,
data base complete.
data base complete.
o Special Data Call-in Fumigant Project consists of certain large volume fumigants which
will be processed through DCI and subject to comparative risk analysis.
Carbon disulfide
Ethylene dichloride
Methyl Bromide
Decision reached - chronic data deferred to standard,
Decision reached - chronic data base complete.
Decision reached - chronic data being generated.
43
-------
DATA CALL-IN - STATUS OF CHEMICALS cont'd
March 1984
o RPAR Decision Data Call-in.
Chemical
Benorayl
EBDC's
Amobam
Mancozeb
Maneb
Metiram
Nabam
Zineb
Piperonyl Butoxide
TrefIan
Status
Decision reached - Field monitoring study being generated,
Letter issued 1/83.
Decision reached - chronic data being generated.
Decision reached - chronic data being generated.
Decision reached - chronic data being generated.
Letter issued 1/83.
Decision reached - chronic data being generated.
Letter issued 9/30/82.
Letter issued 8/82.
o Wood preservatives for industrial, commercial and marine use (R-7).
Potassium bifluoride
Pentachlorophenol
Decision reached - Defer requirements to standard.
Letter issued 2/23/84.
o Fungicides used as seed treatments (F-5).
Chloronitropropane
Fenaminosulf
Hexachlorobenzene
Decision reached - Cancelled/discontinued.
Decision reached - Defer requirements to standard.
Decision reached - Defer requirements to standard.
o Preservatives, disinfectants, slimicides, unclassified uses (R-ll).
Abietylamine
Chromic acid
Chlorobenzene
Dowicil A-40
Dowicide 31,32
Hexylene glycol
Lime
Nitrapyrin
Omadine-sodium
Potassium iodate
Potassium permanganate
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
Decision
reached
reached
reached
reached
reached
reached
reached
reached
reached
reached
reached
Cancelled.
Deferred to
Deferred to
Deferred to
Deferred to
Deferred to
Deferred to
Deferred to
Deferred to
Deferred to
Deferred to
standard.
standard.
standard.
standard.
standard.
standard.
standard.
standard.
standard.
standard
44
-------
March 1984
DATA CALL-IN - STATUS OF CHEMICALS cont'd
o Insecticides used on fruit and nut trees excluding citrus and grapes (1-3).
Chemical Status
Azinphos methyl
Chloropropylate
Cyhexatin
Dormant oil
Diazinon
2-naphthol
Ovex
Phosmet
Propargite
Tetrasul
Vendex
Decision reached - chronic data base complete.
Decision reached - cancelled/discontinued.
Decision reached - chronic data base complete.
Decision reached - no additional chronic data needed,
Decision reached - chronic data being generated.
Decision reached - deferred to standard.
Decision reached - cancelled/discontinued.
Decision reached - chronic data being generated.
Decision reached - chronic data base complete.
Decision reached - cancelled/discontinued.
Decision reached - chronic data base complete.
o Herbicides used on sorghum, rice and small grains (H-4).
Barban
Bromoxynil
Butachlor
Difenzoquat
Methazole
Molinate
Oxadiazon
Propanil
Picloram
Propazine
Terbutryn
Triallate
Decision reached - chronic data being generated.
Decision reached - chronic data being generated.
Decision reached - cancelled/discontinued
Letter issued 8/4/83.
Decision reached - chronic data deferred.
Decision reached - chronic data being generated.
Decision reached - defer requirements to standard,
Decision reached - chronic data being generated.
Decision reached - defer requirements to standard,
Decision reached - chronic data base complete.
Decision reached - chronic data being generated.
Letter being drafted.
45
-------
March 1984
DATA CALL-IN - STATUS OF CHEMICALS cont'd
o Insecticides used on vegetables (1-5).
Chemical
Status
Bacillus thuringiensis
Malathion
Methoxychlor
Mevinphos
Nicotine
Nicotine sulfate
Oxamyl
Oxydemeton methyl
Pirimicarb
Pirimiphos ethyl
Rotenone
Ryanodine
Sabadilla alkaloids
Decision reached - biorational.
Letter issued 2/29/84.
Letter being drafted.
Letter issued 3/28/84.
Letter issued 8/30/83.
Letter issued 8/30/83.
Decision reached - chronic data base complete,
Letter issued 8/11/83.
Decision reached - cancelled/discontinued.
Letter issued 11/18/83.
Letter issued 12/31/83.
Letter issued 11/30/83.
Letter issued 8/22/83.
Herbicides used on citrus, tree fruits, nuts, and sugar cane (H-5).
Ametryn
Asulam
Dichlobenil
Hexazinone
Napropamide
Paraquat
Decision reached - chronic data being generated,
Decision reached - chronic data base complete.
Letter issued 8/18/83.
Decision reached - Defer rqmts. to standard.
Letter issued 8/30/83.
Letter being redrafted.
o Herbicides used on vegetables and tobacco (H-9).
Bisethylxanthogen
CDAA
Chlorpropham
Diphenamid
Endothall
Nitrofen
Prometryn
Letter being drafted.
Letter issued 12/15/83.
Decision reached - chronic data base complete,
Letter issued 2/21/84.
Letter issued 3/12/84.
Decision reached - cancelled.
Letter issued 1/23/84.
46
-------
March 1984
DATA CALL-IN - STATUS OF CHEMICALS cont'd
o Fungicides used on walnuts, pecans, almonds, apples, pears, peaches, cherries,
plums, prunes, and grapes (F-2).
Chemical Status
Ammonium Polysulfide Decision reached - suspended.
Dithianon Letter issued 2/28/84.
2,2- Dithiobisbenzothiazole Letter issued 11/28/83.
Fentin hydroxide Decision reached - Defer rqmts. to standard.
Glyodin Letter being drafted.
Oxythioquinox Letter issued 3/30/84.
Sodium Polysulfide Letter issued 11/23/83.
Streptomycin Letter being drafted.
Ziram Letter issued 2/28/84.
o Herbicides used on sugar beets, beans, and peas (H-6).
Cycloate Letter issued 3/28/84.
Dalapon Letter being drafted.
Desmedipham Letter issued 1/6/84.
Diallate Decision reached - Defer rqmts. to standard.
Dinoseb Letter being drafted.
Ethofumesate Letter issued 11/25/83-.
MCPB Letter issued 11/28/83.
Pebulate Letter being drafted.
Phenmedipham Letter issued 9/12/83.
Propham Letter issued 1/17/84.
Pyrazon Letter issued 11/25/83.
Sodium TCA Letter issued 8/30/83.
o Herbicides used on drainage ditches, rights of way, forestry, and ponds (H-7).
Acrolein Letter issued 12/16/83.
Amitrol Letter being drafted.
Dicnlorprop Letter being drafted.
Diquat Letter being drafted.
47
-------
March 1984
DATA CALL-IN - STATUS OF CHEMICALS cont'd
Herbicides used on drainage ditches, rights-of-way, forestry, and ponds
(H-7) cont'd.
Chemical
Fenac
Karbutilate
MAMA
MSMA
Prometon
Trichlopyr
Status
Letter issued 8/22/83.
Letter issued 2/21/84.
Letter issued 9/26/83.
Letter issued 9/26/83.
Letter issued 8/22/83.
Letter being drafted.
o Insecticides used as mosquito larvicides (1-12).
Dimetnrin
Fenthion
Kerosene
Letter being drafted,
Letter being drafted,
Letter being drafted,
o Insecticides used on livestock and domestic animals (1-6)
Benzyl Benzoate
Bomyl
Bone oil
Butonate
Butoxy Polypropylene glycol
Chlorfenvinphos
Crotoxyphos
Crufornate
Dichlorvos
Diisobutyl Phenoxyethanol
Diphenylamine
Famphur
Lindane
Linseed Oil
Letter being drafted.
Letter issued 11/25/83.
Letter being drafted.
Letter being drafted.
Letter being drafted.
Letter issued 1/19/84.
Letter being drafted.
Decision reached - suspended.
Letter issued - 3/22/83.
Letter being drafted.
Letter being drafted.
Letter issued 11/25/83.
Decision reached - chronic data being
Letter being drafted.
generated,
48
-------
INDEX
Page
Abate® see Temephos
Abietylamine S #004101 44
CAS #51344-60-6
Acephate S #103301 28
CAS #30560-19-1
Acifluorfen S #114401, 114402, 114403 42
CAS # 50594-66-6
sodium salt 62476-59-9
ethyl ester 77207-01-3
Acrylonitrile S #000601 6
CAS #107-13-1
Acrolein S #000701 47
CAS #107-02-8
Alachlor S #090501 28 & 42
CAS #15972-60-8
Alar® see Daminozide
Aldicarb S #098301, 110801 28,31 & 41
CAS #116-06-3
Aldrin/Dieldrin S #45101/45001 8 & 49
CAS #309-00-2 — 60-57-1
Aliette S #123301 31
CAS # 39148-24-8
Aluminum phosphide S #066501 31
CAS #20859-73-8
Ametryn S #080801 46
CAS #834-12-8
4-Aminopyridine S #069201 31
(Avitrol®)
CAS #504-24-5
Amitraz S #106201, 572200 16 & 26
CAS #33089-61-1
Amitrole S #004401 31 & 47
CAS #61-82-5
Ammonium polysulfide S #076701 47
CAS #9080-17-5
Ammonium sulfamate S #005501 31
CAS #7773-06-0
Page
Amobam S #014502 44
CAS #3566-10-7
Anilazine S #080811 31 & 43
CAS #101-05-3
Arsenicals S # Multiple 28
CAS # Multiple
Arsenic trioxide S #007001 6
CAS #1327-53-3
Aspon® S #079101 31
CAS #3244-90-4
Asulam S #106901 46
CAS #3337-71-1
Atrazine S #080803 31 & 42
CAS #1912-24-9
Avitrol® see 4-Aminopyridine
Azinphos methyl S #058001 45
CAS #86-50-0
Bacillus thuringiensis S #006401
CAS #68038-71-1
Barban S #017601 45
CAS #101-27-9
Barium Metaborate S #011101 32
CAS #13701-59-2
Benomyl S #099101 16,17,28 & 44
CAS #17804-35-2
Bentazon and sodium form 28 & 42
S #275200, 103901
CAS #25057-89-0; 50723-80-3
Benzene S #008801 6
CAS #71-43-25-2
Benzyl benzoate S #009501 48
CAS #120-51-4
BHC S #008901 6
CAS # mixed isomers 608-73-1
alpha 319-84-6
beta 319-85-7
gamma 58-89-9 (See Lindane)
delta 319-86-8
-------
Maren 1984
DATA CALL-IN - STATUS OF CHEMICALS cont'd
o Insecticides used on livestock and domestic animals (1-6) cont'd.
Chemical Status
Muscalure Letter issued 1/17/84.
Phenothiazine Letter being drafted.
Piperazine dihydrochloride Letter issued 11/22/83.
Tabatrex Letter issued 9/7/83.
Tetrachlorvinphos Letter being drafted.
o Insecticides used as fumigants and nematicides (1-9).
Carbon Disulfide Letter issued 3/16/84.
Carbon Tetracnloride Letter issued 3/16/84.
Etnylene Dichloride Letter issued 3/16/84.
Methyl bromide Letter issued 3/8/84.
Methylene chloride Letter issued 3/16/84.
o Insecticides used for termite control (1-10).
Aldrin Decision reached - no added data required.
Chlordane Decision reached - no added data required.
Dieldrin Decision reached - no added data required.
Heptachlor Decision reached - no added data required.
49
-------
Page
epsilon 6108-10-7
zeta 6108-11-8
eta 6108-12-9
Bidrin® see Dicrotophos
Bifenox S 1104301, 285200 32
CAS #42576-02-3
Bisethylxanthogen S #086501 46
CAS #502-55-6
BKLFI-2 S #046924 32
CAS #82010-75-1
Bollex S #118501 41
CAS #4175-47-7
Bolstar® see also Sulprofos 32
Bomyl S #084201 48
CAS #122-10-1
Bone Oil S #010801 48
CAS #8001-85-2
Boric acid S #011001 32
CAS #10043-35-3
Bromacil & salts S #012301,02,03,04 32
CAS #314-40-9
dimethylaniine bromide #69484-13-5
lithiumbromacil #53404-19-6
sodium broracil #69484-12-4
Bromoxynil S #035301 45
CAS #1689-84-5
ETC 2125 S #'s 069104,069111 26
CAS #'s 53516-76-0, 8045-21-4
Bufencarb S #059301 40
CAS #8065-36-9
Butachlor S #112301 45
CAS #23184-66-9
Butonate S #035701 48
CAS #126-22-7
Butoxicarboxime see Plantpin®
Butoxy polypropylene glycol S #011901 48
CAS #9007-07-2
Page
Butylate S #041405 32 & 42
CAS #2008-41-5
Cacodylic acid & salts S #012501 10
CAS #75-60-5
Sodium cacodylate 124-65-2
Cadmium S #021001, 02, 05; 1
012901, 02, 236200,
012903, 04, 05; 064601
CAS # for following compounds
anilocadmium dilactate 19651-91-3
cadmium carbonate 513-78-0
cadmium chloride 10108-64-2
cadmium oxide 1306-19-0
cadmium succinate 141-00-4
cadmium sebacate 4476-04-4
cadmium sulfate 10124-36-4
Calcium cyanamide S #014001 43
CAS #156-62-7
Captafol S #081701 28 & 43
CAS #2425-06-1
Captan S #081301 1 & 26
CAS #133-06-2
Carbaryl S #056801 10,28 & 32
CAS #63-25-2
Carbofenothion S #058102 28
CAS #786-19-6
Carbofuran S #090601 28 & 40
CAS #1563-66-2
Carbon disulfide S #016401 43
CAS #75-15-0
Carbon tetrachloride S #016501 1 & 49
CAS #56-23-5
Carbophenothion S #058102 28 & 40
CAS #786-19-6
Carboxin (Vitavax®) S #090201 32
CAS #5234-68-4
CDAA S #019301 46
CAS #93-71-0
-------
Page
Chloramben S #029901, 02, 03, 04, 33
05, 06
CAS 1133-90-4
Chloranil S #079301 6
CAS #118-75-2
Chlordane/Heptachlor 8 & 49
chlordane S #058201
CAS #57-74-9 (cp)
12789-03-6 (tech)
CAS #76-44-8
heptachor S #044801
CAS #76-44-8
Chlordecone (Kepone) S #027701 6 & 8
CAS #143-50-0
Chlordimeform S #059701 28 & 41
CAS #6164-98-3
Chlordimeform hydrochloride S #059702 28 &
CAS #19750-95-9 41
Chlorfenvinphos S #084101 48
CAS #470-90-6
Chlorobenzene S #056504 44
CAS #108-90-7
Chlorobenzilate S #028801 17,28,33 &
CAS #510-15-6 41
Chloroform S #020701 11
CAS #67-66-3
Chloroneb S #027301 33
CAS #2675-77-6
Chloronitropropane S #011302 44
CAS #2425-66-3
Chloropicrin S #081501 33
CAS #76-06-2
Chloropropylate S #026801 45
CAS #5836-10-2
Chlorothalonil S #081901 28 & 43
CAS #1897-45-6
Chlorpropham S #018301 46
CAS #101-21-3
Chlorpyrifos S #059101
CAS #2921-88-2
Chromic acid S #021101
CAS #7738-94-5
Coal tar S #022003
CAS #8007-45-2
Copper acetoarsenite S #022601
CAS #12002-03-8
Copper arsenate (Basic) S #271300
CAS # 16102-92-4
Copper (bordeaux mixture) S #
CAS #8011-63-0
Copper carbonate S #022901
CAS #12069-69-1
Copper naphthenate S #023102
CAS #1338-02-9
Copper oxide S #025601
CAS #1317-38-0 & 1317-39-1
Copper oxychloride S #023501
CAS #8012-69-9
Copper quinolinolate S #024002
CAS #10380-28-6
Copper sulfate basic S #024401
CAS #1344-73-6
Copper sulfate monohydrate
S #024402
CAS #10237-72-6
Coumafuryl see Fumarin®
Coumaphos S #036501
CAS #56-72-4
Creosote S #025004
CAS #8021-39-4
Crotoxyphos S #058801
CAS #7700-17-6
Crufomate S #012101
CAS #299-86-5
Cryolite S #075101
CAS #15096-52-3
28
26
26
Page
& 40
44
1
6
6
43
43
43
43
43
43
& 43
& 43
33
33
2
48
48
& 41
-------
Page
Cyanaz.ine S #100101 28 & 42
CAS ^#21725-46-2
Cycloate S #041301 47
CAS #.1134-23-2
Cycloheximide S #043401 33
CAS #66-81-9
Cyhexatin S #101601 26 & 45
CAS #13121-70-5
Cyprazine S #100401 42
CAS #22936-86-3
Dalapon S #'s 028901,2,3,4 47
CAS #75-99-0; 127-20-8; 29110-22-3
83542-87-4; 83542-88-5
Daminozide (Alar®) S #035101 28
CAS :#1596-84-5
Dasanit see Fensulfothion
2,4-DB S .#030801 4.2
CAS #94-82-6
DBCP .-S-#-011301 8,17 & .18
GAS ;-f 96-12-8
DC-NA rS-#031301 28,33 -&-43
CAS -#9-9--30-9
ODD -S #.029101 8
.CAS .;#7.2-r54-8
DDT .S:#-029201 --8
.CAS -#50-29-3
Deet rS #080301 3:3
GAS 134-T6.2-4
Demeton S -#057601 28 &-41
CAS 8065-48-3
Desmedipham S #104801 47
CAS #13684-56-5
Dialifor S #102501 34
CAS #10311-84-9
Diallate S #078801 18,34 & 47
CAS #2303-16-4
cis #17708-58-6
trans #17708-57-5
Page
Diazrnon S #057801 45
'CAS '#333-41-5
3,5-Dibromosalicylanilide S #077402 26
CAS #87-12-7
Dicamba S #029801, 02, 03, 34 & 42
04, 05, 06
CAS #1918-00-9; 2300-66-5;
25059-78-3; 53404-28-7
53404-29-8; 1982-69-0
Dichlobenil S #027401 46
CAS #1194-65-6
Diclofop methyl S #110902 42
CAS "# 51338-27-3
DrchlOTie S #029601 34
CAS #117-80-6
Dichlorprop S -#031401 47
CAS #120-36-5
Di'chlorvos S -#084001 11 & 48
GAS ~#62- 7 3- 7
Drcofdl •^see'Kelth-ane®
D i c ro t pphecs :S ?# 0 3.5.20 1 34
45
.1 1 . &
26
Diel'dr.rn =see .-Al^r in/Dieldr i-n
Di'fenzoxgu'at -S^#l-a440LL
GAS «#4'.3'2'22-t48-6
D i'f lutee-irz-irron ("D im il in ) S =# 1Q8 201
GAS^#3"5367-38-5
Dirsobutyl phenoxy«.thanol
CAS -#.121-5-4-0
Dimethoate S #035001
CAS -# 6 0-51-5
Dimeth-rin S -#034101
CAS #70-38-2
Dimilin S #108201
CAS #35367-38-5
Dinitramine S #102301
CAS #29091-05-2
S -#0.0150,4 .48
18
41
8 & 42
-------
Page
Dinocap S #036001 43
CAS t39300-45-3
Dinoseb S #'s 037511,2,3,4;037505,6 47
CAS #88-85-7; 6420-47-9; 8048-12-2;
35040-03-0; 6365-83-9;
53404-43-6; 2813-95-8
Dioxathion S #037801 34 & 41
CAS #78-34-2
Diphenamid S #036601 46
CAS #957-51-7
Diphenylamine S #038501 48
CAS #122-39-4
Dipropetryn S #104401 26 & 42
CAS #4147-51-7
Diquat dibromide S #032201 47
CAS #85-00-7
Disulfoton S #032501 29 & 40
CAS #298-04-4
Dithianon S #099201 47
CAS #3347-22-6
2,2-Dithiobisbenzothiazole S #009202 47
CAS #120-78-5
Diuron S #035505 34
CAS #330-54-1
Dodine S #044301 43
CAS #2439-10-3
Dormant oil S # none 45
CAS # none
Dowicide 31:32 S #062208, 10 44
CAS #607-12-5
Dowicil A-40 S #102801 44
CAS #38827-35-9
DSMA S #013802 42
CAS #144-21-8
EBDC's S #014502,3,4,5,6; 014601 19 &
CAS #lll-54-6(Parent); 3566-10-7; 44
142-59-6; 8018-01-7; 12427-38-2;
12122-67-7; 9006-42-2
Page
see amobam, raaneb, nabam,
mancozeb, metiram, zineb
EGT S #042201
CAS #2514-53-6
Endosulfan S #079401
CAS #115-29-7-1
Endothall S #'s 038901,2,3,4,5,6,7;
CAS #145-73-3; 2536-26-7; 129-67-9
2164-07-0; 2536-27-8
Endrin S #041601
CAS #72-20-8
EPN S #041801
CAS #2104-64-5
EPTC S #041401
CAS #759-94-4
Erbon S #028701
CAS #136-25-4
Ethion S #058401
CAS #563-12-2
Ethofumesate S #110601
CAS #26225-79-6
Ethoprop S #041101
CAS #13194-84-4
Ethoxyquin S #055501
CAS #91-53-2
Ethylene dibromide
CAS #106-93-1
Ethylene dichloride
CAS #107-06-2
Ethylene oxide S #042301
CAS #75-21-8
Famphur S #059901
CAS #52-85-7
Fenac S #082601
CAS #85-34-7
Fenaminosulf S #034201
CAS #140-56-7
S #042002
S #042003
42
35
46
20 &
2 &
35 &
35 &
35 &
20 &
43 &
35 &
41
26
42
6
41
47
40
35
21
49
2
48
48
44
-------
Page
Fensulfo.thion S 1032701 29 & 40
CAS #115-90-2
Fenthion S #053301 48
CAS #55-38-9
Fentin hydroxide S #083601 47
CAS #76-87-9
Fenvalerate S #109301 41
CAS #51630-58-1
Ferbam S #034801 43
CAS #14484-64-1
Fluchloralin S #108701 29 & 42
CAS #33245-39-5
Folpet S #081601 43
CAS #133-07-3
Fonofos S #041701 29 & 40
CAS #944-22-9
Formetanate hydrochloride 35 & 41
S #097301
CAS #23422-53-9
Fumarin® (Coumafuryl) S #086001 36
CAS #117-52-2
Glean S #118601 36
CAS #64902-72-3
Glyodin S #043601 47
CAS #556-22-9
Glyphosate isopropylamine
salt S #103601 26 & 42
CAS #38641-94-0
Goal S #111601 21
CAS # 42874-03-3
Gossyplure® S #114101, 02 41
CAS # 53042-79-8, 52207-99-5
Grandlure® S #112401, 02, 03, 04 41
CAS #11104-05-5
HCL S #045901 26
CAS #7647-01-0
Heliothis virus S #107301 29 & 41
CAS # none
Page
Heptachlor see Chlordane Heptachlor
Hexachlorobenzene S #061001 44
CAS #118-74-1
Hexachlorophene S #044901 43
CAS #70-30-4
1,3 Hexanediol (6-12) S #041001 35
CAS #94-96-2
Hexazinone (Velpar®) S #107201 36 & 46
CAS #51235-04-2
Hexylene glycol S #068601 26 & 44
CAS #107-41-5
Hyamine 3500 S #069105 26
CAS # None
Hypochlorites S #014701, 02, 03 36
CAS # for following compounds
sodium 7681-52-9
calcium 7778-54-3
lithium 13840-33-0
Inorganic arsenicals 3 & 28
S #006801, 02 006901, 007001
CAS # for following compounds
arsenic acid 1327-52-2 & 7778-39-4
arsenic pertoxide 1303-28-2
arsenic trioxide 1327-53-3
sodium arsenate 7631-89-2, 10103-60-3,
13464-38-5 & 35794-26-4
ammonium arsenite 58829095-1
sodium pyroarsenate 13464-42-1
lead arsenate (basic) 3687-31-8
lead arsenate 7645-25-2, 7784-40-9 &
10102-48-4
calcium arsenate 7778-44-1
sodium arsenite 7784-46-5
copper acetoarsenite 12002-03-8
Isocyanurates S #081401,2,3,4,5,6,7 7
CAS #126-25-4
isocyanuric acid 108-80-5
isocyanuric chloride 87-90-1
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Page
Page
potassium dichloroisocyanurate 2244-21-5
sodium dichloroisocyanurate 2893-78-9
isocyanuric dichloride 2782-57-2
isocyanuric dichloride,
dihydrate 515 80-86-0
ACL-66 30622-37-8
Isopropalin S #100201 36
CAS #33820-53-0
Karbutilate S #097401 48
CAS #4849-32-5
Kelthane® (Dicofol) S #010501 29
CAS #115-32-2
Kepone see Chlordecone
Kerosene S #063501 48
CAS #8008-20-6
Landrin S #102401, 02 40
CAS #2686-99-9
Lime S #075604 44
CAS #1305-78-8
Lindane S #009001 21,22 & 48
CAS #58-89-9
Linuron S #035506 29
CAS #330-55-2
Linseed Oil S #031603 48
CAS #8001-26-1
Magnesium phosphide S #066504, 218100 36
CAS #12057-74-8
Malathion S #0577 46
CAS #121-75-5
Maleic hydrazide S #051501, 02, 03 12
CAS #123-33-1
MAMA S #013808 48
CAS #2321-53-1
Mancozeb S #014504 44
CAS #8018-01-7
Maneb S #014505, 005050 44
CAS #12427-38-2
MCPA S #030501,2,3; 030553, 56, 62; 36
030563, 66; 030510, 11, 12,
13, 14, 15, 16
CAS #94-74-6; 3653-48-3; 5221-16-9;
6365-62-4; 20405-19-0; 42459-68-7;
42459-69-8; 42459-70-1; 42459-71-2
2039-46-5; 19480-43-4; 1713-12-8;
1713-11-7; 26544-20-7; 2698-40-0
MCPB S #019201 47
Metalaxyl (Ridomil®) S #113501 36
CAS #57837-19-1
Methamidophos (Monitor®) S #101201 36
CAS #10265-92-6
Methanearsonates S #013802, 03, 04, 12
05, 06, 07, 08
CAS # for following compounds
calcium acid 5902-95-4
calcium methanearsonate 5902-97-6
MAMA 2321-53-1
MSMA 2163-80-6
DSMA 144-21-8
octyl ammonium 6379-37-9
docecyl ammonium 53404-47-0
Methazole S #106001 45
CAS #20354-26-1
Methidathion S #100301 37
CAS #950-37-8
Methomyl S #090301, 549400 37
CAS #16752-77-5
Methoprene S #105401, 549500 37
CAS #40596-69-8
Methoxychlor S #034001 46
CAS #72-43-5
S #053201
Methyl bromide
CAS #74-83-9
Methyl parathion
CAS #298-00-0
Methylene chloride
CAS #75-09-2
S #053501
S #042004
43 & 49
41
49
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Page
288700
Metiram S #014601
CAS #9006-42-2
Metolachlor S #108801,
CAS #15972-60-8
Metribuzin S #101101
CAS #21087-64-9
Mevinphos S #015801
CAS #7786-34-7
Mirex S #039201
CAS #2385-85-5
Molinate S #041402
CAS #2212-67-1
Monitor® see Methamidophos
Monocrotophos S #058901
CAS #6923-22-4
Monuron S #035501
CAS #150-68-5
Monuron trichloroacetate S
CAS #140-41-0
MSMA S #013803
CAS #2163-80-6
Muscalure S #103201
CAS #27519-02-4
Nabam S# 014503
CAS #142-59-6
Naled S #034401
CAS #300-76-5
Napropamide S #103001
CAS #15299-99-1
Naptalam S # 030701, 02, 03
CAS #132-66-1
Napthalene S #055801
CAS #91-20-3
Napthaleneacetic acid
03, 04, 07, 08,
CAS #86-87-3
2-napthol S #010301
CAS #135-19-3
44
37
26 & 42
46
45
26 & 41
#035502
7 & 37
37
48
49
44
13,37 & 41
46
27 & 42
37
S #056001, 02, 37
055801, 589300
45
Page
Neomycin sulfate S #006313 27
CAS #1405-10-3
Nicotine S #056702 46
CAS #54-11-5
Nicotine sulfate S #056703 46
CAS #65-30-5
Nitralin S #037601 42
CAS #4726-14-1
Nitrapyrin S #069203 27 & 44
CAS #1929-82-4
Nitrofen S #038201 7 & 46
CAS #1836-75-5
Norflurazon S #105801 29 & 42
CAS #27314-13-2
OBPA (10, 10' Oxybisphen 38
oxarsine) S #012601
CAS #58-36-6
Omadine-sodium S #088004 27 & 44
CAS #15922-78-8
OMPA S #058601 7
CAS #152-16-9
Orthene® see Acephate
Oryzalin S #104201 27 & 42
CAS #19044-88-3
Ovex S #020201 45
CAS #80-33-1
Oxadiazon S #109001 45
CAS #19666-30-9
Oxamyl S #103801 46
CAS #23135-22-0
10,10 Oxybisphenoxarsine see OBPA
Oxydemeton methyl S #058702 46
CAS #301-12-2
Oxyfluorfen S #111601 42
CAS #42874-03-3
Oxythioquinox S #054101 47
CAS #2439-01-2
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Page
Paraquat S #061612
CAS #4685-14-7
Parathion S #057501
CAS #56-38-2
PCNB S #056502
CAS #82-68-8
Pebulate S #041403
CAS #1114-71-2
Pendimethalin S #108501
CAS #40487-42-1
Pentachlorophenol S #063001, 02,
03,08, 09, 10, 11
CAS #87-86-5
sodium pentachlorophenate
potassium "
Perfluidone S #108001, 02
CAS #37924-13-3
Permethrin S #109701
CAS #52645-53-1
Perthane S #032101
CAS #72-56-0
Phenarsazine chloride S #0
CAS #578-94-9
Phenmedipham S #098701
CAS #13684-63-4
Phenothiazine S #064501
CAS #92-84-2
Phorate S #057201
CAS #298-02-2
Phosalone S #097701
CAS #2310-17-0
Phosmet S #059201
CAS #732-11-6
Phosphamidon S #018201
CAS #13171-21-6
Picloram S #005101
CAS #1918-02-1
13
27
29
& 46
& 41
22
47
& 42
& 44
#131-52-2
#7778-73-6
3901
29 &
29 &
42
41
7
7
47
49
40
38
45
41
45
Page
Piperazine dihydrochloride S #067401 49
CAS #142-64-3
Piperonyl butoxide S #067501
CAS #51-03-6
Pirimicarb S #106101
CAS #23103-98-2
Pirimiphos-ethyl S #108101
CAS #23505-41-1
Plantpin® (butoxicarboxim) S #113001
CAS #39196-18-4
Potassium bifluoride S #075203 29 & 44
CAS #7789-29-9
Potassium bromide S #013903
CAS #7758-02-3
Potassium hydroxide S #075602
CAS #1310-58-3
Potassium iodate S #075703
CAS #7758-05-6
Potassium permanganate S #068501 27 & 44
CAS #7722-64-7
Profluralin S #106601
CAS #26399-36-0
Prometon S #080804
CAS #1610-18-0
Prometryn S #080805
CAS #7287-19-6
Pronamide S #101701
CAS #23950-58-5
Propachlor S #019101
CAS #1918-16-7
Propanil S #028201
CAS #709-98-8
Propargite S #097601
CAS #2312-35-8
Propazine S #080808
CAS #139-40-2
Propham S #047601
CAS #122-42-9
13 & 44
46
46
38
29
27
29 & 44
42
48
46
22,23 & 42
29 & 42
45
45
45
47
-------
Pyrazon S #069601
CAS #1698-60-8
Ridomil® see Metalaxyl
Ronnel S #50301
CAS #299-84-3
Rotenone S #071003
CAS #83-79-4
Ryanodine S #071502
CAS #15662-33-6
Sabadilla alkaloids S #002201
CAS #8051-02-3
Safrole S #097901
CAS #94-59-7
Simazine S #080807
CAS #122-34-9
Sodium arsenite S #013603
CAS #7784-46-5
Sodium bentazon S #103901
CAS #50723-80-3
Sodium blsulfate S #073201
CAS #7681-38-1
Sodium fluoroacetate/1080
S #075003
CAS #-£2-74-8
Sodium fryxlr oxide s #075603'
CAS #1310-73-2
Sodium polysulfide S #006902
CAS #1344-08-7
Sodium TCA S #081001
CAS #650-51-1
S,S,S,-tributyl phospho-
rotrithioate (DBF) S #074801
CAS #78-48-8
Streptomycin S #006306
CAS #57-92-1
Strobane S #020401
CAS #8001-50-1
Page
44
14 & 46
46
46
7
38 & 42
7
42
27
4
27
47
4T7
15
47
7
Page
Strychnine/strychnine sulfate 23 & 24
S # 076901, 02
CAS #57-24-9
CAS #60-41-3
Sulfur S #077501 38
CAS #7704-34-9
Sulfuryl Fluoride S #078003 27
CAS #2699-79-8
Sulprofos (Bolstar®) S #111501 38
CAS #35400-43-2
Tabutrex S #077802 49
CAS #141-03-7
2,4,5-T/Silvex S #.082501 9 & 25
CAS #93-765, 93-72-1
TCBC S #017304 42
CAS 1344-32-7
TCC S #027901 27
CAS #101-20-2
Tebu,thiuron. S #105501 29
CAS #34014-18-1.
Temephos (Aba£€®) S $059001 38
CAS t33.B3-9.6-8
1081 ST #075002. 14
CAS. $sfe4t)-lS—7
TJ2PJP S. ft-079601. 40
CAS. #107-49.-3:
Terbacil S" #r012TQl 38
CAS #3330.2-51-2.
Terbufjos S #105001. 38
CAS #13071-79-9
Terbutryn S #080813 14 & 45
CAS #886-50-0
Terrazole® S #084701 39
CAS #2592-15-9
Tetrachlorvinphos S #083701 49
CAS #961-11-5
Tetradifon S #079202 41
CAS #116-29-09
-------
Tetrasul S #079201
CAS #2227-13-6
Thiophanate ethyl S #103401
CAS #23564-06-9
Thiophanate methyl S #102001
CAS #23564-05-8
Thiram S #079801
CAS #137-26-8
Toxaphene S #080501
CAS #8001-35-2
TPTH S #83601
CAS #76-87-9
Treflan S #036101
CAS #1582-09-8
Triadimefon S #109901
CAS #43121-43-3
Triallate S #078802
CAS #2303-17-5
S,S,S-Tributyl Phosphoro-
trithioate (DBF) S #074801
CAS #78-48-8
Tributyl phosphorotri-
thioite (Merphos) S #074901
CAS #150-50-5
Trichlopyr S #116001,2
CAS #'s 55355-06-3;57213-69-l
Trichlorfon S #057901
CAS #52-68-6
2,4-5-Trichlorophenol S
11, 12f 14,
CAS #95-95-4
Trifluralin S #036101
CAS #1582-09-8
Trysben (Benzac) S #017303
CAS #3426-62-8; 1338-32-5
Velpar® see Hexazinone
Vendex S #104601
CAS #13356-08-6
24
29
24
14
Page
45
27
& 27
& 43
& 25
30
44
43
& 45
#064204, 10
17, 19, 20
15
15
48
15,30 & 40
4
25
7
45
Vernolate S #041404
CAS #1929-77-7
Vitavax® see Carboxin
Warfarin S #086002, 086003
CAS #81-81-2
sodium warfarin #129-06-6
potassium warfarin #2610-86-8
Zinc phosphide S #088601
CAS #1314-84-7
Zineb S #014506
CAS #12122-67-7
Ziram S #034805,6
CAS #137-30-4; 16509-79-8
Page
42
39
39
44
47
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