24552 . 1984 SEPTEMBER 1984 STATUS REPORT on REBUTTABLE PRESUMPTION AGAINST REGISTRATION (RPAR) OR SPECIAL REVIEW CHEMICALS, REGISTRATION STANDARDS PROGRAM, AND DATA CALL-IN PROGRAM (Report contains information as of September 31, 1984) OFFICE OP PESTICIDE PROGRAMS (TS-767C) U.S. ENVIRONMENTAL PROTECTION AGENCY 401 M STREET, S.W. WASHINGTON, D.C. 20460 ------- TABLE OF CONTENTS SPECIAL REVIEW PROGRAM RPARs Issued PRE-RPAR Review Final Actions (voluntary Cancellations) Notice of Intent to Cancel/Suspend Notice of Intent to Register (Returned to Registration Div.) RPAR1s Completed REGISTRATION STANDARDS Registration Standards Development - Data Collection Registration Standards Development - Data Evaluation and Development of Regulatory Position » Registration Standards Issued DATA CALL-IN * . . . Index of Chemicals Included in status report Prepared by: Registration Support and Emergency Response Branch Registration Division (703) 557-7700 Date Prepared: November 1984 ------- REGISTRATION DIVISION DIRECTOR DEPUTY DIRECTOR Insecticide-Rodenticide Branch PM 12 Jay Ellenberger PM 15 George LaRocca PM 16 William Miller PM 17 Timothy Gardner Fungicide-Herbicide Branch PM 21 Henry Jacoby PM 23 Richard Mountfort PM 25 Robert Taylor Disinfectants Branch PM 31 John Lee PM 32 Arturo Castillo Special Review Branch Registration Support and Emergency Response Branch PM 43 Hoyt jamerson PM 45 Bhushan Mandava DATA CALL-IN PROGRAM Douglas D. Campt Robert V. Brown Herbert Harrison James Akerman Juanita Wills Paul Lapsley Ferial Bishop (703) (703) (703) (703) (703) (703) (703) (703) (703) (703) (703) (703) (703) (703) (703) (703) 557-7760 557-7760 557-2200 557-2386 557-2400 557-2600 557-2690 557-1650 557-1900 557-1830 557-1800 557-3661 557-3675 557-3965 557-7420 557-7700 Geraldine Werdig (703) 557-1192 (703) 557-7700 (703) 557-7436 ------- PREFACE This publication contains: 1) an alphabetical listing of all chemicals which have been, or are being, handled under the Rebuttable Presumption Against Registration [RPAR] process, (revisions to the process and name change to Special Review are planned), 2) an alphabetical listing of the chemicals which have been through or are now active in the Registration Standard development process, and 3) identification by cluster of the chemicals which have been through or are being processed in the Data Call-in program. These processes are managed by the Registration Division, Office of Pesticide Programs, Office of Pesticides and Toxic Substances, EPA. This listing is intended for internal use and is updated semi-annually. Users of this document are encouraged to contact the appropriate PM or Branch Chief, as noted, if they have any questions or corrections regarding the entries in this listing. Sections of the law referred to in this document are from the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) as amended 7 U.S.C. Section 136. All chemicals are listed by the names under which they were or are being reviewed. Other widely used common or chemical names may also appear in the Index. Copies of most of the position documents (PD) and Registration Standards are available from the National Technical Information Service (NTIS), U.S. Department of Commerce, 5285 Port Royal Road, Springfield, Virginia, 22161 (703) 487-4600. The accession- number and costs for paper copy and/or microfiche are cited for those documents presently available from NTIS. When requesting documents from the NTIS, state the name of the document, the NTIS publication (PB. Accession Number, enclose proper payment (check payable to NTIS) and provide a return mailing address. RPAR PROCESS* Definitions of the risk criteria that, when met or exceeded, can trigger RPAR analyses, can be found in the Federal Register of July 3, 1975 (40 CFR 162.11). These risk criteria are concerned with the following areas: 1. Acute Toxicity 2. Chronic Toxicity A. Oncogenic B. Mutagenic *This process is also referred to as the "Special Review Process", and is used interchangeably with the "RPAR Process". ------- 3. Other Chronic Effects A. Reproductive (1 ) Fetotoxicity (2) Teratogenicity B. Spermatogenicity C. Testicular Effects D. Neurotoxicity E. Others 4. Significant reduction in wildlife, reduction in endangered species, and reduction in nontarget species. 5. Lack of emergency treatment or antidote. RPAR CATEGORIES The name of this process will be changed from "RPAR" to "Special Review" pursuant to the new regulations which are planned for proposal in the near future. That is why for purposes of this report the terms may be used interchangeably. This report is divided into a number of categories to enable the reader to conveniently determine the current status of a particular pesticide. Pre-RPAR — This is the initial risk investigation phase that involves an intensive review of the scientific studies of the chemical in question that suggest that the RPAR criteria may have been met or exceeded. A validation of these studies of the chemical in question is conducted by Agency scientists. During this period, the registrants of the pesticide are notified that a RPAR criteria may have been met or exceeded. If "trigger studies" are found to be valid, an effort is valid, an effort is made to assess the significance of the risk posed by a pesticide use. After an RPAR has been initiated, discussions are held with registrants and other interested parties in an attempt to reduce risk to acceptable levels. If the risk is reduced to acceptable levels, the RPAR review is terminated. If the Agency determines that an RPAR risk criteria has been met or exceeded, the document des- cribing this determination is referred to as position document one (PD 1). Issuance of an RPAR--After a PD 1 is published, a 45 day period is allowed for comment on the presumptions against registration presented in PD 1. A 60 day extension is granted, if justified. Therefore, there is typically a 105 day period within which the Agency's presumptions may be rebutted. Risks may be rebutted by interested parties submitting to the Agency: (1) proof that the i i ------- study or studies upon which the presumption is based are not scientifically valid or (2) proof that actual exposure to the compound will not cause the effects described. This phase of the process can be characterized as focusing on the gathering of additional information in the form of: — rebuttal comments. —additional information on risk. — input from other agencies: primarily the United States Department of Agriculture for information on benefits and exposure, and the United States Department of Interior, Office of Endangered Species for information on any effects from the pesticide use on endangered species. In the event that all the triggers have been successfully rebutted, the pesticide is re- turned to the registration process and the RPAR is terminated for all or some of the uses. The results of this phase of the analysis is incorporated into a second position document (PD 2) which states the Agency's regulatory action for the pesticide. Any new information that surfaced during the rebuttal period is incorporated. The Agency only produces and publishes a separate PD 2 in those cases where rebuttal has been successful and the PD 2 ends the RPAR process in these cases. When the rebuttal is not successful, a rebuttal assessment, risk assessment, benefits analysis, risk/benefit analysis, and a proposed regulatory position are presented in a document termed PD 2/3. A PD 2/3 is composed of: -- the introductory chapter which reviews the data which gave rise to the RPAR on the pesticide in question, — an analysis of and response to rebuttal comments, — the risk analysis which qualitatively and quantitatively describes the risks associated with the currently registered uses of the pesticide. -- the benefit analysis which estimates the impact of cancellation of the pesticide in question, — the risk/benefit analysis of each of the regulatory options under considera- tion for resolution of the RPAR, and — the recommended regulatory position. The full range of regulatory options which are available under the law are examined. These range from full registration to full cancellation. Between the two ends of the regulatory spectrum are the options that deal with labeling changes, classification, and use restrictions. The impact of each of these options on the benefits and risk of each 111 ------- use of the pesticide are considered. The recommended decision is that which presents the best balance of risks and benefits in the interest of public health and the environment. A notice of preliminary determination and an announcement of the PD 2/3's availability are published in the Federal Register. The FIFRA requires that the proposed decision (PD 2/3) be submitted to a Scientific Advisory Panel for review of its scientific basis and to the Secretary of Agriculture for comment. These comments, plus any industry or public comments on the proposed decision, are evaluated. The Agency's assessment of these comments, including the final decision on the regulatory action, are announced in the Federal Register. These are contained in publi- cation PD 4 which is also announced in the Federal Register. Activities After Completion of RPAR's—This document describes the status of those chemicals that have, through a variety of means, concluded their RPAR analyses. This includes chemicals which have been returned to the registration process, those which have been cancelled or on which restrictions have been imposed, and those which are currently in administrative hearings etc . REGISTRATION STANDARDS The Registration Standards program is EPA's approach to the reassessment and reregistra- tion of pesticide products as mandated by Congress in FIFRA Section 3 (g). The reassessment involves a thorough review of the scientific data base underlying pesticide registrations and an identification of essential but missing scientific studies which may not have been required when the product was initially registered. It may also require new testing or retesting to ensure the safety of the compound by contemporary scientific standards. The standards process involves making broad regulatory decisions at one time for a group of pesticide products containing the same active ingredient rather than on a product-by- product basis. About 600 active ingredients, representing 35,000 currently-registered products could potentially require Registration Standard review. However, given assump- tions about chemicals not requiring review due to voluntary cancellations, suspensions, and other reasons, the actual number of standards to be developed is substantially less than that. This approach to reregistration is intended to simplify and streamline the regulatory process for both the Agency and pesticide registrants and to assure the public that all registrations are supported by a complete and valid scientific data base. To establish the sequence of processing the approximate 600 active ingredients through the Registration Standard review, active ingredients that have similar use(s) have been IV ------- clustered into 48 groups. The groups are being processed in a sequence resulting from their ranking in an equation based on production, human exposure, and ecological exposure factors. The ranking scheme was developed based on consideration of market competition, availability of in-depth data on alternatives should the need for a Special Review arise, and efficient use of EPA resources. Each standard explains EPA's regulatory position on the use of the active ingredient in all pesticide products containing that same chemical. The standard contains an analysis of the data on which the regulatory position is based, describes the rationale for the regulatory position, and states the conditions that must be met to obtain pesticide product registration. The relationship of the Registration Standards process with the Special Review process is that if the analysis of the data shows that a Special Review criterion has been met, then the standard is issued announcing that a Special Review will be initiated for some or all of the uses of the chemical and a proposed regulatory decision or "PD 2/3" will be issued, Registration Standards are developed in three phases: (1) Data Gathering, (2) Data Evaluation, and (3) Regulatory Position Development followed by the issuance of the Registration Standard Guidance Package. For convenience, phases 2 and 3 are combined in this report and the issued documents are identified separately in the attached listing. (1) Data Gathering: The bibliography consists of all data in Agency files pertaining to the chemical, except that in most cases efficacy data are not listed. The bibliography will also include any government studies (such as NCI studies) which have been conducted on the chemical and other relevant material identified by Agency scientists. Agency scientists identify which studies should be reviewed; after which, hard copy of all requested studies are retrieved from Agency files and provided to Agency scientists for review. The data gathering phase lasts about five months. Once the data-gathering phase is completed, and the use information is developed, the data evaluation phase is ready to begin. (2) Data Evaluation: At the outset of the Data Evaluation phase, the Project Support Team, which consists of all Agency staff involved in the Registration Standard review (Regis- tration/reregistration Product Manager, use experts, data retrieval experts, and Agency scientists) meet to exchange information regarding the chemical from a regulatory and scientific perspective. This meeting is designed to provide a context in which the scien- v ------- tists conduct their review. Knowledge of the regulatory history, the growth patterns of the chemical's use, general understanding of the completeness of the data base, and discussion of any past regulatory/health problems will help focus the review and increase the scientists' effectiveness. With this perspective, scientists review data in each of five disciplines: product chemistry, environmental fate, residue chemistry, toxicology, and ecological effects. Efficacy data are reviewed only for products which control infectious microorganisms and the growth of aflatoxins. The scientists document their review of each study which they consider relevant, and prepare a summary of what is known about the chemical in their respective discipline. Scientists also identify gaps in the data base which should be filled to enable a complete scientific assessment to be made. While the 40 CFR Part 158 guidelines* (currently proposed) are used as guidance to make the determination of data gaps, each chemical is reviewed individually to determine, given its particular use patterns and what is already known about it, what additional data are needed. If the resulting data needs differ from those in the Guidelines, the scientist provides written justification for the deviation. Depending on the size ot the data base involved in the review, this phase usually lasts from six to ten months. (3) Development of Regulatory Position and Issuance of Guidance Package; Once the Science review is completed and scientists have recommended which additional data they believe are necessary to complete the review, the project Support Team reconvenes to identify the appropriate regulatory position for the chemical (that is, what percent active ingredient, formulations, uses, etc. are registrable under the Standard and whether regulatory restrictions such as label warnings or use by certified applicators only are required). They also develop the rationale for the regulatory position and determine the data requirements which need to be imposed to complete the review. Included in this phase is the tolerance reassessment which may result in the initiation of rulemaking to increase or decrease tolerance levels. A document summarizing these findings, including the proposed regulatory position and rationale, data requirements, scientific summaries, and bibliography, is then circulated to support team members and Agency management for review. After the document is approved, study reviews and science summaries are placed in Agency records for retrieval during subsequent reviews of the chemical (e.g. registration amendments] as their availability is expected to expedite the processing of future reviews. Copies of the study reviews and the science summaries are available through OPP's Freedom of Information [See p. vii for specific citation. v i ------- Section. The regulatory position/rationale, data requirements, and bibliography are sent to the registrant in a document known as a Guidance Package which cites the authority of Section 3(c)(2)(B) and Section 3 (g) of FIFRA. Reregistration occurs when the registrant agrees to comply with the data requirements, submits an updated Confidential Statement of Formula if needed, agrees to comply with any regulatory restrictions placed on the chemical, agrees to compensate other registrants for data considered relevant to the Standard, and provides labelling reflecting completion of any product chemistry and acute toxicity data requirements. Issuance of the Standard; The standard is issued to the registrants and made available to the public through the National Technical Information Service, 5285 Port Royal Road, Springfield, VA 22152 telephone 703-487-4650. Microfilm copies are available for $4.50; the price of paper copies varies according to the length of the document. Please furnish NTIS with the report title and the NTIS order/report number (PB Number) when ordering. THE DATA CALL-IN PROGRAM The Data Call-in Program requires existing registrants of active pesticide chemicals to provide the Agency with needed studies under Section 3(c)(2)(B) of FIFRA. Such studies, including chronic toxicology, product chemistry, residue and environmental fate data are an integral part of the data base used to reassess each chemical during the reregistration process or to resolve special concerns such as whether the chemical enters groundwaters. The purpose of Data Call-in is to assure that these data are available or well underway before the pesticide chemical is reassessed for reregistration under Section 3(g) or other purposes. The four types of long-term toxicological data which have been traditionally requested consist of Chronic Feeding, Oncogenicity, Reproduction and Teratogenicity (informally referred to as the CORT studies). These studies are described in the Toxicology Data Requirements' part of the "Pesticide Registration: Proposed Data Requirements" regulation.* The product chemistry, residue, and environmental fate studies are also described in this regulation. *The Pesticide Registration Guidelines were reproposed as Part 158, 40 CFR on November 24, 1982 in 47 Federal Register 53192. Vll ------- Under the Data Call-in Program, the Agency: (1) determines which types of data are required for each chemical, based on its use patterns and other factors; (2) identifies those test categories with no valid data submitted; and (3) ensures that studies are initiated by registrants of the pesticide to fill those data gaps. In general, the sequence of processing the active ingredients through the Data Call-in Process is based on the priority cluster ranking in which active ingredients that have a similar use(s) are clustered into about 50 groups and the groups are processed in sequence. A notice of the availability of the final cluster ranking was published in the Federal Register, 47 FR 3770, January 24, 1982. The cluster ranking is not followed when special concerns arise about a chemical or a particular group of chemicals. During FY 85, the program will be focused on processing the remaining food-use chemicals. In each Notice, the registrant can request the Agency to exempt or waive any or all of the specified data requirements. Registrants may request changes of or exemptions from the data requirements because: 1. They believe they are a formulator or end-user. 2. They determine that their chemical involves only minor exposure and production. In addition, registrants may cite economic factors as precluding its capacity to incur the costs of testing. 3. They wish to remove all registered uses which involve food crops/products and/or significant repeated exposure to humans and the environment. 4. They believe the data requirements do not apply to the registered uses of their product(s). If the Agency does not grant the change(s) or exemption(s), the registrants must arrange to comply with the Notice. If a registrant does not respond or comply with the Data Call-in Notice, the Agency issues an Administrative Notice (NOIS—Nlotice Of Ijitent to Suspend) compelling the registrant to stop distributing the particular pesticide product(s) until compliance with the Notice occurs. The actual effect of a NOIS is to put a registration "on hold" until such time as the registrant wishes to comply with the notice and make his registration active. Any such NOIS issued under Section 3(c)(2)(B) is rescinded when the Agency is informed and agrees that compliance occurs. Such NOIS's never, independently, result in cancellations and are therefore clearly different from the FIFRA Section 6 suspensions which can later become cancellations and cause the withdrawal of pesticide products from the market. VI 1 1 ------- This report gives the status of chemicals and clusters being processed through Data Call-in. The status includes whether a Notice or equivalent has been issued and whether the Agency has reached a final decision on all the waivers, exemptions, cancellations, commitments and offers received from registrants. IX ------- RPAR's ISSUED SEPTEMBER 1984 CHEMICAL (Class of Chemicals) and CONTACT PERSON 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS CADMIUM (Special Review Br. ) CAPTAN (Special Review Br.) CARBON TETRACHLORIDE (Special Review Br.) COAL TAR (Special Review Br.) o Oncogenicity o Mutagenicity o Teratogenicity o Fetotoxicity o Oncogenicity o Mutagenicity o Other Chronic Effects o Oncogenicity o Toxic effects on liver and kidney o Oncogenicity o Mutagenicity o PD 1 published 42 PR 56574 on 10/26/77; comment period closed 2/10/78. o Risk/benefit assessment is planned for in FY 85. o PD 1 published 45 PR 54938 on 8/18/80; comment period closed 12/1/80: NTIS# PB81 109449. o Risk/benefit assessment is ongoing o PD 1 published 45 PR 68534 on 10/15/80; comment period closed 11/24/80: NTIS# PB81-121782 o Risk/benefit assessment is ongoing PD 1 published 43 PR 48154 on 10/18/78; comment period closed 9/30/78: NTIS# PB80 213879. PD 2/3 (wood uses only) completed and Notice of Determination pub- lished in 46 FR 13020 on 2/19/81; comment period closed 5/20/81; Report No. 540/9-82-004; NTIS# PB82-229956. At 4/14/83 public meeting, proposed conclusion presented. Comment period closed 5/13/83. PD 2/3 (non-wood) use) completed and Notice of Preliminary Determination published in FR 8/22/84. Comment period closed 10/20/84. Final deci- sion scheduled for FY 86. ------- RPAR's ISSUED SEPTEMBER 1984 CHEMICAL (Class of Chemicals) and CONTACT PERSON 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS COAL TAR (cont'd) (Special Review Br CREOSOTE (Special Review Br . ) o Oncogenicity o Mutagenicity o Oncogenicity o Mutagenicity o o EPN (Ethyl p-nitro phenyl thionoben- zenephosphonate (PM-12) o Neurotoxicity o o o PD 4 (wood uses only) completed and final decision published in 46 FR 13020. Same as above (Coal Tar/Creosote Coal Tar Neutral Oil PD 1 and PD 2/3 combined). PD 2/3 (wood uses only) completed and Notice of Determination pub- lished in 46 FR 13020 on 2/19/81; comment period closed 5/20/81. Report No. 540/9-82-004; NTIS# PB82-229956. At 4/14/83 public meeting proposed conclusion presented. Comment period closed 5/13/83. PD 2/3 (non-wood use) completed and Notice of Preliminary Determination published in FR 8/22/84. Comment period closed 10/20/84. Final deci- sion scheduled for FY 86. PD 4 (wood uses only) completed and final decision published in 46 FR 13020. PD 1 published 44 FR 54384 on 9/19/79; comment period closed 12/29/79. NTIS# PB80 216815. Final Notice of Determination and Decision Document forwarded to Acting AA on 6/30/83. Final Notice of Determination signed by Acting AA and published 48 FR 39494 ------- RPAR's ISSUED September 1984 CHEMICAL (Class of Chemicals) and CONTACT PERSON 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS ETHYLENE OXIDE EtO (Special Review Br. ) o Oncogenicity o Mutagenicity o Testicular Effects INORGANIC ARSENICALS Arsenic Acid , Arsenic Pentoxide, Arsenic Trioxide, Sodium Arsenate, Ammonium Arsenite, Sodium, Pyroarsenate, Lead Arsenate Basic and Standard) Calcium Arsenate, Sodium Arsenite, Copper Acetoarsenite (Special Review Br.) PENTACHLOROPHENOL AND DERIVATIVES (Special Review Br.) o o o o o o Oncogenicity Mutagenicity Teratogenicity Oncogenicity Fetotoxicity Teratogenicity o PD 1 published 43 FR 3801 on 1/27/78; comment period closed 5/15/78. NTIS# PB80-213903. o Label changes requiring modifica- tion workplace design and workplace practice for sterilization of equip- ment and supplies used in hospitals and health care facilities signed on 3/30/84. o PD 1 published 43 FR 42867 on 10/18/78; comment period closed 2/12/79. o PD 2/3 (wood uses only) completed and Notice of Determination pub- lished 46 FR 13020 on 2/19/81; comment period closed 5/20/81. o At 4/14/83 public meeting proposed conclusion presented. Comment period closed 5/15/83. o Final decision being developed and not due until FY 1985. PD 1 published 43 FR 48443 on 10/18/78; comment period closed 2/12/79. NTIS# PB81-109464. PD 2/3 (wood used only) completed and Notice of Determination pub- lished 46 FR 13020 on 2/19/81; comment period closed 5/20/81. ------- RPAR'S ISSUED September 1984 CHEMICAL (Class of Chemicals) and CONTACT PERSON 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS PENTACHLOROPHENOL AND DERIVATIVES (Cont'd) (Special Review Br, o o o SODIUM FLUORO- ACETATE (1080) (Special Review o Br. ) 2,4-5-TRICHLORO- PHENOL (Special Review Br o Oncogenicity Fetotoxicity Teratogenicity Reduction in Non-target and Endangered Species No antidote Oncogenicity Fetotoxicity o At 4/14/83 public meeting proposed conclusion presented. Comment period closed 5/13/83. o PD 2/3 (non-wood use currently being developed. o PD 4 (wood uses only) completed and final decision published in 46 FR 13020. o PD 1 published 41 FR 52792 on 12/1/76; comment period closed 3/15/77. NTIS# PB80-216823. o PD 2/3 signed on 11/11/82 and re- signed on 6/29/83. Issuance of document was delayed until 6/83 to coincide with that of document addressing predator issues and was published 48 FR 50935 on 11/4/83. o SAP reviewed PD 2/3 on 12/83 and final report on 7/3/84 following 6/12/84 SAP meeting. o PD 1 published 42 FR 41268 on 9/15/78; comment period closed 11/17/78. NTIS# PB81-103111. o Some voluntary cancellations and reformulations being processed. o 3(c)(2)(B) letter will be issued in FY 1985 requesting updated Confiden- tial Statement of Formula and an analysis for dioxin contamination. ------- PRE-RPAR REVIEW September 1984 CHEMICAL (Class of Chemicals) and CONTACT PERSON 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS RONNEL rophenyl) phosphoro- thioate (related to 2,4,5-T) (Special Review Br.) o Oncogenicity o No action; pending 2,4,5-T hearing o 3(c)(2)(B) letter will be sent to registrants to update Confidential Statement of Formula in FY 85. ------- FINAL ACTIONS VOLUNTARY CANCELLATIONS September 1984 CHEMICAL (Class of Chemicals) 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED DATE OF FR PUBLICATION AND NTIS PUBLICATION NUMBER ACRYLONITRILE (three products) ARSENIC TRIOXIDE o Oncogenicity o Teratogenicity o Neurotoxicity o Oncogenicity o Mutagenicity o Teratogenicity BENZENE o Oncogenicity (all except one product) o Mutagenicity and Blood Disorders BHC CHLORANIL CHLORDECONE Kepone (Products of six formulators) COPPER ACETOARSENITE o Oncogenicity o Oncogenicity o Oncogenicity o Oncogenicity o Mutagenicity o Teratogenicity o 43 FR 26310 (6/19/78). o 42 PR 45944 (9/13/77). o Voluntary cancellations completed. o 43 FR 31432 (7/21/78) NTIS# PB80-216781. o 42 FR 3702 (1/19/77). o 42 FR 38205 (7/27/77) NTIS# PB80-216773. O 42 FR 18422 (4/7/77). COPPER ARSENATE (Basic) (all products) ENDRIN o Oncogenicity o Reduction in Endangered Species and Non-Target Species o 42 FR 18422 (4/7/77). o 49 FR 42792 (10/24/84) ------- FINAL ACTIONS VOLUNTARY CANCELLATIONS September 1984 CHEMICAL (Class of Chemicals) 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED DATE OF PR PUBLICATION AND NTIS PUBLICATION NUMBER ERBON ISOCYANURATES (some products MONURON (some products NITROFEN (TOK) OMPA OctamethyIpyro- phosphoramide PERTHANE (many products) PHENARSAZINE CHLORIDE SAFROLE SODIUM ARSENITE (two products) o Oncogenicity o Teratogenicity o Fetotoxicity o Kidney effects o Oncogenicity o Teratogenicity o Mutagenicity o Oncogenicity o Oncogenicity o Oncogenicity o None o Oncogenicity o Mutagenicity o Oncogenicity o Mutagenicity o Teratogenicity o 45 FR 58770 (10/4/80) . o Registrants have undertaken numerous toxicological stud- ies. The last study will be completed 12/85. o 42 FR 41320 (8/16/77). o Product voluntarily can- celled on 9/15/83. o 41 FR 21859 (5/28/76). o 45 FR 41694 (6/20/80). o 42 FR 59776 (11/21/77) o 42 FR 11039 (2/25/77). o 42 FR 16844 (3/30/77). o 42 FR 29957 (6/10/77). o 43 FR 48267 (10/18/78) STROBANE o Oncogenicity o 41 FR 26607 (6/28/76). ------- FINAL ACTIONS VOLUNTARY CANCELLATIONS September 1984 CHEMICAL (Class of Chemicals) 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED DATE OF FR PUBLICATION AND NTIS PUBLICATION NUMBER TRYSBEN o Oncogenicity o 43 FR 5782 (2/9/78). ------- NOTICE OF INTENT TO CANCEL/SUSPEND ISSUED SEPTEMBER 1984 CHEMICAL (Class of Chemicals) 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED DATE OF FR PUBLICATION AND NTIS PUBLICATION NUMBER ALDRIN/DIELDRIN CHLORDANE/HEPTACHLOR CHLORDECONE Kepone DBCP ODD (TDE) DDT DINITRAMINE MIREX 2,4,5-T/SILVEX o Oncogenicity o Reductions in Non-target and endangered species o Oncogenicity o Oncogenicity o Mutagenicity o Reproductive Effects o Oncogenicity o Oncogenicity o Teratogenicity o Fetotoxicity o 39 FR 37246 (10/18/74) (cancellation of most uses) o 39 FR 41298 (11/26/74) (cancellation of most uses) o 42 FR 18885 (4/11/77). o 44 FR 65135 (10/29/79) (cancellation of all uses except pineapple) o 36 FR 5254 (3/18/71) o 37 FR 13369 (7/7/72) (cancellation of most uses). o Notice of Intent to Suspend under Sec. 3(c)(2)(B) issued on 9/28/82. o 41 FR 56703 (12/29/76). (cancellation of most uses). o 44 FR 15874 (3/15/79) NTIStt PB80-225923 (2,4,5-T) NTIS# PB80-226376 (Silvex). ------- NOTICE OF INTENT TO REGISTER ISSUED (Returned to the Registration Process) September 1984 CHEMICAL (Class of Chemicals) 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED DATE OF FR PUBLICATION AND NTIS PUBLICATION NUMBER CACODYLIC ACID AND SALTS (PM-23) o Oncogenicity o Mutagenicity o Teratogenicity CARBARYL (PM-12) o Oncogenicity o Mutagenicity o Teratogenicity o Insufficient evidence to issue a RPAR. Decision document published 47 FR 20376 on 5/12/82. Returned to the Registration process in 12/81 with the stipulation that pursuant to FIFRA Section 3(c)(2)(B), data on the rate of dermal absorption be submitted, knapsack/hand sprayer applicators treating ditch banks and rights-of-way will wear respirators or masks, and labels recommend masks for homeusers employing knapsacks or hand sprayers. The data has been sub- mitted and the Agency has not imposed labeling changes. Published 45 FR 81869 on 12/12/80. The Agency has returned this com- pound to the registration process with the stipulation that the follow- ing measures be considered: (1) a FIFRA Section 3(c)(2)(B) action that registrants remedy data gaps iden- tified in pre-RPAR review and (2) appropriate label changes be made to minimize exposure to Carbaryl, Both measures are being considered in the reregistration review of this chemical. Registration Standard issued 3/30/84. 10 ------- NOTICE OF INTENT TO REGISTER ISSUED (Returned to the Registration Process) September 1984 CHEMICAL (Class of Chemicals) 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED DATE OF FR PUBLICATION AND NTIS PUBLICATION NUMBER CHLOROFORM Trichloro- methane (PM-16) o Oncogenicity DICHLORVOS DDVP 2 ,2-dichlorovinyl dimethyl phosphate (PM-15) o Oncogenicity o Mutagenicity o Reproductive Effects o Fetotoxicity o Neurotoxicity DIFLUBENZURON Dimilin (PM-17) o Oncogenicity o Hazard to Wildlife and Other Chronic Effects o PD 1 published 41 FR 14588 on 4/6/76; comment period closed 7/23/76. o FR Notice announcing termination of this RPAR issued in December, 1982. The agency determined that applicator exposure had been reduced to a minimum as a result of label amendments. Also regis- trants were required to submit data to establish tolerances of permissible residues on raw agricultural commodities. o Published 47 FR 45075 on 10/13/82. (NTIS # not available). Returned to the registration process on 9/29/82, stating that the Agency will reas- sess carcinogenic potential and the need for additional Oncogenicity data upon completion of an in-progress bioassay which is still in progress at RTP. Additional tests on mutagenic- ity were required. Task Force has developed protocols to initiate tests. Actual studies have not been submitted but final reports due 3/25/85. o RPAR action completed in April 1979. Registrant consented to restricted uses, Decision Document was issued 9/30/82 and Agency concluded that existing evi- dence does not support issuance of a 11 ------- NOTICE OF INTENT TO REGISTER ISSUED (Returned to the Registration Process) September 1984 CHEMICAL (Class of Chemicals) 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED DATE OF FR PUBLICATION AND NTIS PUBLICATION NUMBER DIFLUBENZURON Dimilin (Cont'd) (PM-17) MALEIC HYDRAZIDE MH (PM-25) o Oncogenicity o Hazard to Wildlife and Other Chronic Effects o Oncogenicity o Mutagenicity o Reproductive Effects METHANEARSONATES includes Amine Methanearsonate, Calcium Acid Meth- anearsonate, Mono- ammonium Methane- arsonate (MAMA), Monosodium Methane- arsonate (MSMA), Disodium Methane- arsonate (DSMA) (PM-23) o Oncogenicity o Mutagenicity RPAR and consequently, that a RPAR for Trichlorfon as a precursor of Dichlorvos, was not warranted. o PD 1 published 42 FR 56920 on 10/28/77; comment period closed 12/14/77: NTIStt PB80 216740 o Decision document signed 6/28/82, returning maleic hydrazide and salts (K-MH, DEA-MH) to registration pro- cess. NTIS# PB82-240300. FR Notice has been combined with Chloroform (see Chloroform). o All required data has been submitted to the Agency. o Registrants decided not to per- form similar tests on DEA-MH and thus DEA-MH was suspended 11/81. o On 6/28/83 the pre-RPAR review for methanearsonate chemicals was completed and a decision memo was approved returning these chemicals to the normal registration process. The existing evidence was inadequate to initiate an RPAR for the chemicals. o 3(c)(2)(B) letter sent 9/26/83 requir- ing a chronic feeding, Oncogenicity, teratology, and applicator exposure studies in order to determine if there are any risk concerns. 12 ------- NOTICE OF INTENT TO REGISTER ISSUED (Returned to the Registration Process) September 1984 CHEMICAL (Class of Chemicals) 40 CPR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED DATE OF FR PUBLICATION AND NTIS PUBLICATION NUMBER METHANEARSONATES (Cont'd) NALED (PM-16) o Oncogencity o Mutagenicity o Mutagenicity o Fetotoxicity o Reproductive 10,10'Oxybisphen- oxarsine (some uses) (PM-22) PARAQUAT (PM-25) PIPERONYL BUTOXIDE (PM-17) Effects o Arsenical Compound suspected: . Oncogenicity . Mutagenicity . Teratogenicity o Emergency Treatment o Chronic Effects o Co-Carcinogenicity o Carcinogenicity Company is presently conducting the studies. Chemical returned to normal registra- tion process on 6/30/83. Based on a re- view of all available data, no valid tests or definitive evidence exist which meet or exceed the RPAR risk criteria. However, per registration standard, additional tests are required and due 6/86; and will be reviewed to determine whether there are any risks of concern. Based on Decision Document of 4/9/79 indicating no evidence of oncogenicity, chemical was returned to the registra- tion process. o Decision document returning paraquat to the registration process was signed on 6/29/82. Published 47 FR 45075 on 10/23/82. (NTIS # not available.) Decision Document outlines data gaps and voluntary cancellation of certain noncrop use sites. o Decision document published 47 FR 20376 on 5/12/82. NTIS# PB83-137901. Chemical returned to the registration process and a Section 3(c)(2)(B) Notice requesting additional data issued on 9/30/82. 13 ------- NOTICE OF INTENT TO REGISTER ISSUED (Returned to the Registration Process) September 1984 CHEMICAL (Class of Chemicals) 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED DATE OF FR PUBLICATION AND NTIS PUBLICATION NUMBER PIPERONYL BUTOXIDE (PM-17) (Cont'd) o Co-Carcinogenicity o Carcinogenicity o Agency has received commitments from certain registrants to conduct the required studies to be submitted between now and 1987. ROTENONE (PM-17) 1081 (Fluoro-acetamide) (PM-16) TERBUTRYN (PM-25) TRIALLATE (PM-25) o o o o o o o o o o o o Oncogenici ty Mutagenic ity Teratogenici ty Reproductive Effects Chronic Toxicity Significant Wildlife Populations Reductions Acute Toxicity to Aquatic Wildlife Acute Toxicity to Mam- malian and Avian Species Reduction in endangered and non target species Acute Toxicity without antidote. o Oncogen ici ty Mutagenicity Reproductive o o o Effects Oncogenici ty Mutagenicity Decision Document published 46 FR 36745 on 7/15/81. (NTIS # not available.) Chemical returned to registration process based on finding no unreasonable adverse effects. PD 1 published 41 NTIS# PB80-216823 PD 2 published 45 NTIS# PB80-216831 Chemical returned cess with used only FR 52792 on 12/1/76. FR 13189 on 2/28/80. to registration the restriction that it in sewers. pro- be Pre-RPAR evaluation completed. Chemical returned to the registration process. Registrants agreed to change label to reduce applicator risk to acceptable levels. Notice published 47 FR 20376 on 5/12/82. (NTIS # not ava ilable.) o Published 45 FR 82349 on 12/15/80. (NTIS # not available.) The Agency 14 ------- NOTICE OF INTENT TO REGISTER ISSUED (Returned to the Registration Process) September 1984 CHEMICAL (Class of Chemicals) 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED DATE OF PR PUBLICATION AND NTIS PUBLICATION NUMBER TRIALLATE (cont'd) (PM-25) o Oncogenicity o Mutagenicity S,S,S-TRIBUTY PHOSPHOROTHRITHIOATE (DBF) (PM-25) o Neurotoxicity TRIBUTYL PHOSPHORO- TRITHIOATE (Merphos) (PM-25) o Neurotoxici. ty TRICHLORFON (PM-16) o Oncogenicity o Mutagenicity o Teratogenicity o Fetotoxicity o Reproductive Effects determined that, in light of the low level of exposure, chemical should be returned to the registra- tion process stipulating that a FIFRA 3(c)(2)(B) action be initiated to obtain necessary toxicity data to evaluate its hazards. o 3(c)(2)(B) was issued on 6/15/84 to include the data needs. o Pre-RPAR evaluation completed. Returned to Registration Division 11/30/81, based on finding of no potential unreasonable adverse effects. Registrants agreed to practice clothing requirement. Published 47 FR 20376 on 5/12/82. (NTIS # not available.) o PRE-RPAR evaluation completed. o Based on finding no potential unrea- sonable adverse effects, chemical returned to registration process. Registrants agreed to protective clothing requirement. Published 47 FR 203765 on 25/12/82. (NTIS # not available.) o Removed from Pre-RPAR review as it chemically relates to Dichlorvos. See Dichlorvos. o Existing evidence does not support issuance of an RPAR for this chemical 15 ------- NOTICE OF INTENT TO REGISTER ISSUED ^Returned to the Registration Process) September 1984 CHEMICAL (Class of Chemicals) 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED DATE OF FR PUBLICATION AND NTIS PUBLICATION NUMBER TRICHLORFON (PM-16) (cont'd) o o o o o Oncogenicity Mutagenici ty Teratogenic i ty Fetotoxicity Reproductive Effects On 9/30/83, similar action was taken on DDVP, a metabolite of Trichlorfon Registration Standard issued 7/19/84, 16 ------- RPAR's COMPLETED September 1984 CHEMICAL (Class of Chemicals) and RESPONSIBLE BRANCH 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS AMITRAZ (Baam) (PM-12) o Oncogenicity BENOMYL (PM-21 o Reduction in non-target o Mutagenicity o Teratogenicity o Reproductive Effects o Hazard to Wildlife o PD 1 published 42 FR 18299 on 4/6/77; comment period closed 7/18/77: NTISI PB80-212046. o PD 2/3 completed and Notice of Determination published 44 FR 2678 on 1/12/79. Comment period closed 2/12/79. NTIStt PB80-211436. o PD 4 published 44 FR 32736 on 6/7/79; 44 FR 59938 on 10/7/79 (correction). NTIS# PB80-211428. . conditional registration approved for pears but not for apples. . registrants submitted an oncogen- icity study in 1/84 and will col- lect additional benefits data. . tolerance for pears approved 12/6/79. o PD 1 published 42 FR 61788 on 12/6/77. o PD 2/3 completed and Notice of Determination published 44 FR 51166 on 8/30/79: comment period closed 9/28/79. o PD 4 completed and Notice of Determination published 47 FR 46747 on 10/20/82. NTIS# PB83-148189. The Notice reguires use of either cloth or commercially available disposable dust masks by mixer/loaders of benomyl intended for aerial application and that registrants of benomyl products conduct field monitoring studies to identify residues that may enter 17 ------- RPAR'S COMPLETED September 1984 CHEMICAL (Class of Chemicals) and RESPONSIBLE BRANCH 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS BENOMYL (cont'd) (PM-21) CHLOROBENZILATE (PM-12) o o o o o Reduction in non-target Mutagenicity Teratogenicity Reproductive Effects Hazard to Wildlife o Oncogenicity o Testicular Effects DBCP 1 , 2-dibromo- 3-chloropropane (PM-21) o Oncogenicity o Reproductive Effects aquatic sites after use on rice o 3(c)(2)(B) letter issued 3/83. Registrant presently conducting field monitoring study which is to be completed. o PD 1 published 41 FR 21517 on 5/26/76; comment period closed 7/28/76. o PD 2/3 and Notice of Proposed Deter- mination published 43 FR 29824 on 7/11/78. Comment period closed 8/10/78. NTIS# PB80-213887. o Final Determination based on PD 2/3 published 43 FR 29824 on 7/11/78). o PD 4 and Notice of Intent to Cancel published 44 FR 9547 on 2/13/79. NTIS# PB80-213929. o PD 1 published 42 FR 48026 on 9/22/77. Comment period closed 11/7/77. o Suspension Order and Notice of Intent to Cancel published 42 FR 57543 on 11/3/77. o Amended Notice of Intent to Cancel and PD 2/3/4/ published 43 FR 40911 on 9/13/78. NTIS# PB80-213853. o Notice of Intent to Suspend All Pro- ducts Issued published 44 FR 41783 on 7/18/79. o Suspension Order (presently in effect 18 ------- RPAR's COMPLETED September 1984 CHEMICAL (Class of Chemicals) and RESPONSIBLE BRANCH 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS DBCP (cont'd) (PM-21) o Oncogenicity o Reproductive Effects DIALLATE (PM-25) o Oncogenicity Mutagenicity DIMETHOATE (PM-16) o Oncogenicity o Mutagenicity o Fetotoxicity o Reproductive Effects for all uses except pineapple) and Notice of Intent to Cancel All Uses published 44 PR 65135 on 10/29/79. o Agreement reached with registrants that all uses, except on pineapples, are cancelled. o Proposed Intent to Cancel DBCP Use on Pineapples published in 49 FR 1556 on 1/12/84. Final Notice is being drafted and scheduled for AA signature 11/84. o PD 1 published 42 FR 27669 on 5/31/77;, comment'period closed 9/9/77: NTIS# PB80-212863. o PD 2/3 completed and Notice of Determination published 45 FR 38437 on 6/9/80; comment period closed 7/9/80: NTIS# PB80 216849: o PD 4 completed and announced in Federal Register, 47 FR 27109 (6/23/82). (NTIS # not available.) o Classifies current products for restricted use by certified applicators wearing protective clothing. o PD 1 published 42 FR 45806 on 9/22/7. Comment period closed 1/6/78. o PD 2/3 completed and Notice of Determination published 44 FR 66558 on 11/19/79. Comment period closed 12/19/79. NTIS# PB80-213846. 19 ------- RPAR'S COMPLETED September 1984 CHEMICAL (Class of Chemicals) and RESPONSIBLE BRANCH 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS DIMETHOATE (cont'd) (PM-16) EBDC'S Ethylenebis- dithiocarbamates, maneb, mancozeb, metiram, nabam, zinab, amoban, (PM-21 ) ENDRIN (PM-15) o Mutagenicity o Fetotoxicity o Reproductive effects o o o o o o Oncogenicity Teratogenicity Hazard to Wildlife Oncogenicity Teratogenicity Reduction in endangered species and nontarget species o PD 4 published 46 FR 5334 on 1/19/81. (NTIS # not available.) Registration Standard approved and signed 3/31/83. o PD 1 .published 42 FR 40618 on 8/10/77; comment period closed 12/23/77. o Decision Document and Final Determination published 47 FR 47669 on 10/27/82. (NTIS ft not available.) The Notice returned EBDC products to the registration process on condition that certain use precautions are added to the product labels and registrants agree to generate additional toxicology data. o Data Call-in Notices requesting registrants to generate the needed data on 6 EBDC's and ETU have been issued. o Registrants committed to generate data for all chemicals except Amobam. (See page 44.) o PD 1 published 41 FR 31316 on 7/26/76. Comment period closed 11/4/76. NTIS# PB81-112690. o PD 2/3 completed and Notice of Pro- posed Determination published 43 FR 51132 on 11/2/78. o PD 4 published (including cancel- lations) 44 FR 43631 on 7/25/79. 20 ------- RPAR'S COMPLETED September 1984 CHEMICAL (Class of Chemicals) and RESPONSIBLE BRANCH 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS ENDRIN (cont'd) (PM-15) EPN (PM-12) o Oncogenicity o Teratogenicity o Reduction in endangered species and nontarget spec ies o Neurotoxicity ETHYLENE DIBROMIDE (EDB) (Special Review Br.) o Oncogenicity o Mutagenicity o Reproductive Effects NTIS# PB81-10980. o PD 4 follow-up notice mailed 8/28/80. Cancellations began 30 days later. . Some uses are conditionally regis- tered because requirements have been met. o All remaining uses have been volun- tarily cancelled effective 9/12/84. o PD 1 published 44 FR 54384 on 9/19/79; comment period closed 12/29/79: NTIS# PB80-216815. o Final Notice of Determination and Decision Document forwarded to Acting AA on 6/30/83. o Final Notice of Determination signed by Acting AA on 6/30/83 and published 48 FR 39494 on 8/31/83. o PD 1 published 42 FR 63134 on 12/14/77; comment period closed 4/3/78: NTIS# PB80-109456. o PD 2/3 completed and Notice of Determination published, 45 FR 81586 on 12/10/81; comment period closed 3/9/81. o PD 4 and FR Notice were approved on 9/28/83. Emergency suspension of o Emergency Suspension on uses to fumi- gate grain and grain milling equipment published 49 FR 4452 on 2/6/84. o Proposed tolerances for EDB in grains 21 ------- RPAR'S COMPLETED September 1984 CHEMICAL (Class of Chemicals) and RESPONSIBLE BRANCH 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS ETHYLENE DIBROMIDE (EDB) (cont'd) (Special Review Br.") o Oncogenicity o Mutagenicity o Reproductive Effects GOAL (PM-23) o Oncogenicity published 49 FR 56 on 2/22/84. o Proposed tolerances for EDB in citrus and papayas published 49 FR 806 on 3/6/84. o Final tolerances for EDB in grains published 49 FR 17144 on 4/23/84. on 4/23/84. o Amendment to Notice of Intent to Cancel Registrations of Pesticide Products Containing EDB published 49 FR 70 on 4/10/84. o Final Revocation of Tolerances and Establishment of Interim Tolerances for EDB in Citrus and Papaya published 49 FR 103 on 5/25/84. o Proposed Revocation of Tolerances and Establishment of Interim Tolerances for EDB in Mangoes published 49 FR 156 on 8/10/84. o Proposed Revocation of Tolerances for Miscellaneous Commodities published 49 FR 156 on 8/10/84. o PD 1/2/3 completed. NTIS# PB82-185133 o PD 4 published 47 FR 27118 on 6/23/82. NTIS# PB82-172289. o The decision is to continue use of the herbicide subject to certain restrictions (on PCE) pertaining to formulation of the product. 22 ------- RPAR'S COMPLETED September 1984 CHEMICAL (Class of Chemicals) and RESPONSIBLE BRANCH 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS LINDANE (Special Review Br.) o Oncogenicity o Teratogenicity o Reproductive Effects o Acute Toxicity o Other Chronic Effects PCNB Pentachloro- nitrobenzene (PM-21) o Oncogenicity o PD 1 published 42 FR 9816 on 2/18/77. Comment period closed 6/20/77. NTIS# PB80-213861. o PD 2/3 completed and Notice of Determination published 45 FR 45362 on 7/3/80. Comment period closed 9/15/80. o PD 4 and Decision Document were signed on 9/30/83. Notice published 48 FR 48512-48522 on 10/19/83. The deci- sion cancels the indoor use of smoke fumigation devices and the use of dog dips to treat pests other than mites. All other uses will continue with use restrictions and label modi- fications. o Negotiated settlement on dog dips pub- lished 49 FR 26282 on 6/27/84. A set- tlement on smoke bombs is about to be signed which will phase out this use by 5/31/86. o PD 1 published 42 FR 61894 on 10/13/77; comment period closed 2/6/78: NTIS #PB80-216799. o PD 2/3 in Agency review. o RPAR terminated through negotiated agreement with registrants to reduce levels of the HCB contami- nant and to make lable changes to reduce exposure. Published 47 FR 18177 on 4/19/82. 23 ------- RPAR's COMPLETED September 1984 CHEMICAL (Class of Chemicals) and RESPONSIBLE BRANCH 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS PRONAMIDE (PM-25) o Oncogenicity o PD 1 published 42 FR 32302 on 5/20/77. Comment period closed 8/29/77. NTIS #PB81 109472. o PD 2/3 completed and Notice of Proposed Determination published 44 FR 3083 on 1/15/79. Comment period closed 2/14/79. NTIStf PB81-112682. o PD 4 completed and Final Determina- tion published 44 FR 61640 on 10/26/79. NTIStt PB81-112716. The following actions were taken: Can- cellation of registrations of pro- ducts allowing hand spray applica- tions, except for use on ornamentals and nursery stock; cancellation of registrations of products unless the registrant modifies the terms and conditions to allow certain uses of wettable powder products only by or under direct supervision of certified applicators; modification of labeling of wettable powder products to include specific general precautions, direc- tions as to protective clothing to be worn, dilution instructions for wet- table powder products, and watering instructions for granular products used on turf; and Agency revision of the lettuce tolerance from 2 ppm to Ippm from required residue data that was submitted. 24 ------- RPAR'S COMPLETED September 1984 CHEMICAL (Class of Chemicals ) and RESPONSIBLE BRANCH 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS STRYCHNINE/ STRYCHNINE SULFATE (Special Review Br. ) o Reduction in Non-target and Endangered Species 2,4 ,5-T/Silvex o o o Oncogenicity Teratogenic ity Fetotoxicity o PD 1 published 42 FR 2713 on 1/13/77; comment period closed 3/15/77: NTIS# PB80-216807. o PD 2/3 completed and Notice of Determination published 45 FR 73602 on 11/5/80. Comment period closed 9/30/81. NTIS# PB81-123960. o PD 4 and decision package were approved on 9/30/83. Published 48 FR 48522 on 10/19/83. Decision cancels use of strychnine for control of prairie dogs and several other rodents and small mammals. All other uses will require label modi fications. o PD 1 published 43 FR 17116 (4/21/78). NTIS# PB80-212665. o Emergency Suspension Order and Notice of Intent to Cancel published 44 FR 15874 (3/15/79). 2,4,5-T—NTIS # PB80-22592; Silvex—PB80 226376. o PD 4 completed and Final Determination published 44 FR 72316 on 12/13/79. o Cancellation Hearings began 3/14/80. o On 10/11/84, the Administrative Law Judge gave Union Carbide 30 days to determine if they want to defend 2,4,5-T/Silvex uses or not. The remaining companies will determine if they want to defend the case upon Union Carbide's reply. 25 ------- RPAR's COMPLETED September 1984 CHEMICAL (Class of Chemicals ) and RESPONSIBLE BRANCH 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS THIOPHANATE METHYL (PM-21) o Mutagenicity o Reduction in Non- target Species (Rebutted) TOXAPHENE (PM-12) o Oncogenicity o Population reduction non-target animal species o Acute toxicity to aquatic organisms o Chronic effects to wildlife o PD 1 published 42 FR 61940 on 12/7/77; comment period closed 3/27/78: NTIS fPB80-216856, o PD 2 completed and Notice of Proposed Determination pub- lished 44 FR 58798 on 10/11/79. o PD 4 completed and Notice of Determination published 47 FR 46747 on 10/20/82. NTIS # not available. o PD 1 published 42 FR 26860 on 5/27/77; comment period closed 9/13/77: NTIS# PB80-216732. o Decision Document published 11/29/83. o Final Notice of Determination pub- lished in 47 FR 53784 on 11/29/82. NTIS# PB83-144204. o Notice applies to cancellation of registrations for most uses and con- tinued registration of certain uses under specific terms and conditions. The continued uses are: corn, cotton, and small grain for specific insect infestation (emergency use only), pineapples and bananas for specific insects in Puerto Rico and the Virgin Islands only, and scabies treatments of cattle and sheep. 26 ------- RPAR's COMPLETED September 1984 CHEMICAL (Class of Chemicals) and RESPONSIBLE BRANCH 40 CFR 162.11 CRITERIA POSSIBLY MET OR EXCEEDED CURRENT STATUS TRIFLURALIN (TrefIan) (PM-23) o Oncogenicity o Mutagenicity o PD 1/2/3/ published 44 FR 50911 on 8/30/79. Comment period closed 11/13/79. NTIS# PB80-213937. o PD 4 published 47 FR 33777 on 8/4/82. Report No. 540/9-82-011; NTIS# PB82-263252. o Trifluralin registrations allowed to continue if the total N-nitro- samine contamination is kept below 0.5 ppm for technical products and below a figure based on Trifluralin content for formulated products. 27 ------- REGISTRATION STANDARDS DEVELOPMENT - DATA COLLECTION September 1984 CHEMICAL (Class of Chemicals) RESPONSIBLE RD BRANCH/PM TYPE OF CHEMICAL AMITRAZ BTC 2125 CAPTAN COPPER SULFATE & related hydrates CYHEXATIN 3,5-Dibromosalicylanilide DIFLUBEN2URON DIPROPETRYN EPN FORMALDEHYDE GLYPHOSATE HYAMINE 3500 METRI6UZIN MONOCROTOPHOS NAPTALAM I-R Branch/PM-12 Disinfectants Br./PM-31 H-F Branch/PM-21 H-F Branch/PM-21 I-R Branch/PM-12 Disinfectants Br./PM-32 I-R Branch/PM-17 H-F Branch/PM-25 I-R Branch/PM-12 Disinfectants Branch/PM-31 H-F Branch/PM-25 Disinfectants Branch/PM-31 H-F Branch/PM-25 I-R Branch/PM-16 H-F Branch/PM-25 Insect ic ide Disinfectant Fungicide Fung ic ide Insect ic ide Disinfectant Insect icide Herbicide Insect icide Dis infectant Herbicide Disinfectant Herbicide Insecticide Herbicide 28 ------- REGISTRATION STANDARDS DEVELOPMENT - DATA COLLECTION September 1984 CHEMICAL (Class of Chemicals RESPONSIBLE RD BRANCH/PM TYPE OF CHEMICAL NEOMYCIN SULFATE NITRAPYRIN OMADINE-SODIUM ORYZALIN PARATHION POTASSIUM PERMANGANATE SULFURYL FLUORIDE TCC THIOPHANATE Ethyl THIOPHANATE Methyl H-F Branch/PM-21 H-F Branch/PM-23 Disinfectants Br./PM-31 H-F Branch/PM-25 I-R Branch/PM-12 H-F Branch/PM-23 I-R Branch/PM-16 Disinfectants Br./PM-32 H-F Branch/PM-21 H-F Branch/PM-21 Fung icide Herbicide Dis infectant Herbicide Insect icide Herbicide Insecticide Disinfectant Fung ic ide Fung icide 29 ------- REGISTRATION STANDARDS DEVELOPMENT - DATA EVALUATION AND DEVELOPMENT OF REGULATORY POSITION September 1984 CHEMICAL (Class of Chemicals) RESPONSIBLE RD Branch/PM TYPE OF CHEMICAL ACEPHATE ALACHLOR ALDICARB BENOMYL BENTAZON (and sodium form) CAPTAFOL CARBARYL CARBOPHENOTHION CARBOFURAN CHLORDIMEFORM CHLORDIMEFORM HCL CHLOROBENZILATE CHLOROTHALONIL CHLORPYRIFOS CYANAZINE I-R Branch/PM-16 H-F Branch/PM-25 I-R Branch/PM-12 H-F Branch/PM-21 H-F Branch/PM-25 H-F Branch/PM-21 I-R Branch/PM-12 I-R Branch/PM-16 I-R Branch/PM-12 I-R Branch/PM-12 I-R Branch/PM-12 I-R Branch/PM-12 H-F Branch/PM-21 I-R Branch/PM-12 H-F Branch/PM-25 Insect icide Herbicide Insecticide Fung icide Herbic ide Fung icide Insect ic ide Insect icide insecticide Insecticide Insecticide Insecticide Herbicide Insect icide Herbicide 30 ------- REGISTRATION STANDARDS DEVELOPMENT - DATA EVALUATION AND DEVELOPMENT OF REGULATORY POSITION September 1984 CHEMICAL (Class of Chemicals) RESPONSIBLE RD BRANCH/PM TYPE OF CHEMICAL DAMINOZIDE (Alar) DEMETON DICOFOL DISULFOTON FENSULFOTHION FLUCHLORALIN (Basalin) FONOFOS HELIOTHIS VIRUS INORGANIC ARSENICALS LINURON NORFLURAZON PENDIMETHALIN (Prowl) PHORATE PICLORAM POTASSIUM BROMIDE H-F Branch/PM-25 I-R Branch/PM-16 I-R Branch/PM-12 I-R Branch/PM-15 I-R Branch/PM-15 H-F Branch/PM-25 I-R Branch/PM-16 I-R Branch/PM-17 H-F Branch/PM-21 H-F Branch/PM-25 H-F Branch/PM-23 H-F Branch/PM-25 I-R Branch/PM-16 SR Branch Disinfectants Br./PM-32 Herbicide Insecticide Insecticide Insecticide Insecticide Herbicide Insecticide Insecticide Fungicide Herbicide Herbicide Herbicide Insect icide Herbicide Disinfectant 31 ------- REGISTRATION STANDARDS DEVELOPMENT - DATA EVALUATION AND DEVELOPMENT OF REGULATORY POSITION September 1984 CHEMICAL (Class of Chemicals) RESPONSIBLE RD BRANCH/PM TYPE OF CHEMICAL POTASSIUM IODATE PROPACHLOR TEBUTHIURON THIRAM TPTH(Triphenyltin Hydroxide) TRICHLORFON Disinfectants Br./PM-32 H-F Branch/PM-25 H-F Branch/PM-25 H-F Branch/PM-21 H-F Branch/PM-21 I-R Branch/PM-16 Disinfectant Herbicide Herbicide Fung icide Fungicide Insecticide 32 ------- REGISTRATION STANDARDS - ISSUED September 1984 CHEMICAL & REPONSIBLE TYPE OF DATE OF PRODUCT MANAGER (PM) IN CHEMICAL STANDARD REGISTRATION DIVISION & NTIS NOS . ALDICARB (PM 12) ALIETTE (PM 22) Insecticide March NTIS# Fungicide June NTIS# 30, 1984 PB84-207653 30, 1983 PB84-206564 DATE OF GUIDANCE PACKAGE & EPA DOCUMENT NOS. 3/30/84 6/30/83 ALUMINUM PHOSPHIDE (PM 16) 4-AMINOPYRIDINE (AVITROL) (PM 16) AMITROLE (PM 25) AMMONIUM SULFAMATE (PM 25) Insecticide Bird Chemosterilants Toxicants and Repellents Herbicide Herbicide October 1981 NTIS# PB82-137514 September 1980 NTIS# PB84-209907 March 30, 1984 June 1981 NTIS# PB82-133570 11/24/81 RS-81-017 9/30/80 RS 81-0003 3/30/84 8/5/81 RS-81-012 ANILAZINE (PM 21) ASPON (PM 16) ATRAZINE (PM 25) BARIUM METABORATE (PM 22) Herbicide Insecticide Herbicide Fung ic ide December 13, 1983 12/13/83 NTIS# PB84-168301 September 1980 9/30/80 NTIS# PB84-206549 September 30, 1983 NTIS# PB84-149451 April 14, 1983 6/27/83 NTIS# PB84-168376 33 ------- REGISTRATION STANDARDS - ISSUED September 1984 CHEMICAL & REPONSIBLE PRODUCT MANAGER (PM) IN REGISTRATION DIVISION BIFENOX (PM 25) BKLFI-2 (PM 32) BORIC ACID (pending 25(b) (PM 16) BROMACIL & SALTS (PM 25) BUTOXICARBOXIME (PLANTPIN) (PM 12) BUTYLATE (PM 25) CARBARYL (PM 12) CARBOFURAN (PM 12) CARBOPHENOTHION (PM 16) CARBOXIN (VITA VAX®) TYPE OF CHEMICAL Herbicide Disinfectant exemption decision) Herbicide i Insecticide Herbicide Insecticide Insect ic ide Insecticide Fungicide DATE OF STANDARD & NTIS NOS. June 1981 NTIS# PB82-007 December 1981 NTIS# PB82-002 September 1982* September 1981 NTIS# PB82-177585 September 1983* March 1984 NTIS# PB84-232602 June 1984* July 1984* August 1981 DATE OF GUIDANCE PACKAGE & EPA DOCUMENT NOS. 8/12/81 RS-82-007 12/29/81 RS-82-002 9/30/82* 9/30/81 RS-82-004 9/30/83 RS-83-017 3/30/84 6/25/84 7/31/84 8/12/81 (PM 21) NTIS# PB82-132994 RS-81-007 * NTIS number not available. 34 ------- REGISTRATION STANDARDS - ISSUED September 1984 CHEMICAL & RESPONSIBLE PRODUCT MANAGER (PM) IN REGISTRATION DIVISION CHLORAMBEN (PM 25) CHLOROBENZILATE (PM 12) CHLORONEB (PM 21) CHLOROPICRIN (PM 21) CHLORPYRIFOS (PM 12) COUMAPHOS (PM 15) CRYOLITE (PM 17) CYCLOHEXIMIDE (PM 21) DCNA (PM 21) DEBT (PM 25) TYPE OF CHEMICAL Herbicide Insecticide Fungicide Insecticide Insecticide Insecticide Insect icide Fung icide Herbicide Insecticide DATE OF STANDARD & NTIS NOS. August 1981 NTIS# PB82-134347 December 1983 NTIS# PB85-107605 September 1980 NTIS# PB81-123804 September 1982* September 1984* August 1981 NTIS# PB82-133357 June 23, 1983 NTIS# PB84-211945 September 1982 NTIS# PB84-211945 September 1983 NTIS# PB84-210178 December 1980 NTIS# PB81-277722 DATE OF GUIDANCE PACKAGE & EPA DOCUMENT NOS. 8/12/81 RS-81-015 12/20/83 9/30/80 9/28/82 9/28/84 9/4/81 RS-81-013 6/28/84 9/24/82 12/14/83 12/2/80 RS-81-004 * NTIS number not available. 35 ------- REGISTRATION STANDARDS - ISSUED September 1984 CHEMICAL & RESPONSIBLE PRODUCT MANAGER (PM) IN REGISTRATION DIVISION DIALIFOR (PM 16) DIALLATE (PM 25) DICAMBA (PM 25) DICHLONE (PM 21) DICOFOL (PM 12) DICROTOPHOS (BIDRIN®) (PM 16) DIMETHOATE TYPE OF CHEMICAL Insecticide Herbicide Herbicide Fungicide Insecticide Insecticide Insecticide DATE OF STANDARD & NTIS NOS. July 1981 NTIS# PB82-133638 March 31, 1983* September 1983 NTIS# PB84-243492 March 1981 NTIS# PB81-207383 December 1983 NTIS# PB84-160084 April 1982 NTIS# PB82-204383 March 31, 1983* DATE OF GUIDANCE PACKAGE & EPA DOCUMENT NOS. 7/31/81 RS-81-014 4/7/83 9/30/83 3/16/81 RS-81-001 12/30/83 6/30/82 4/11/83 (PM 16) DIOXATHION (PM 15) DIURON (PM 25) ENDOSULFAN (PM 15) Insecticide Herbicide Insecticide March 31, 1983* 4/7/83 September 1983 9/28/83 NTISt PB84-210327 March 1982 6/25/82 NTIS# PB82-243999 * NTIS number not available. 36 ------- REGISTRATION STANDARDS - ISSUED September 1983 CHEMICAL & RESPONSIBLE PRODUCT MANAGER (PM) IN REGISTRATION DIVISION EPTC (PM 25) ETHION (PM 16) ETHOPROP (PM 16) ETHOXYQUIN (PM 25) 2 ETHYL 1,3 HEXANEDIOL( 6-12 ) (PM 17) FENAMINOSULF (PM 21) FENSULFOTHION (PM 15) FONOFOS (PM 16) FORMETENATE HYDROCHLORIDE (PM 12) FUMARIN (COUMAFURYL) TYPE OF CHEMICAL Herbicide Insecticide Nematicide Growth Regulator Insecticide Fung ic ide Insect ic ide Insecticide Insecticide Rodent Toxicant DATE OF STANDARD & NTIS NOS. September 1983* December 1982* June 23, 1983 NTIS# PB84-210194 March 1981* June 1981 NTIS# PB81-234098 September 1983* December 1983* March 1984 NTIS# PB84-210186 September 1983 NTIS# PB84-141456 September 1982 DATE OF GUIDANCE PACKAGE & EPA DOCUMENT NOS. 9/30/83 12/23/82 6/24/83 3/81 RS-81-011 6/5/81 RS-81-005 9/30/83 12/22/83 3/30/84 9/23/83 10/21/80 (PM 16) and Anticoagulant NTIS# PB81-123812 * NTIS number not available. 37 ------- REGISTRATION STANDARDS - ISSUED September 1984 CHEMICAL & RESPONSIBLE PRODUCT MANAGER (PM) IN REGISTRATION DIVISION GLEAN® (CHLORSULFURON) (PM 25) HEXAZINONE (VELPAR) (PM 23) HYPOCHLORITE Salts (PM-32) ISOPROPALIN (PM 25) MAGNESIUM PHOSPHIDE (PM 16) MCPA (PM 23) METALAXYL (RIDOMIL®) (PM 21) METHAMIDOPHOS (MONITOR®) (PM 16) METHIDATHION (PM 12) METHOMYL (PM 12) TYPE OF CHEMICAL Herbicide Herbicide Disinfectant Herbicide Insecticide Herbicide Fungicide Insecticide Insecticide Insecticide DATE OF STANDARD & NTIS NOS. September 1982* February 1982* January 13, 1983 August 1981 NTIS# PB82-131293 March 1982 NTISf PB82-195777 March 1982* August 1981 NTIS# PB82-172297 September 1982* January 13, 1983 September 1981 NTIS# PB82-180738 DATE OF GUIDANCE PACKAGE & EPA DOCUMENT NOS. 9/30/82 4/27/82 ** 8/5/81 RS-81-009 3/29/82 RS-82-006 6/30/82 8/31/81 RS-82-005 9/24/82 1/14/83 1/22/82 RS-82-001 * NTIS number not available. ** Guidance package pending in Office of General Counsel (OGC) 38 ------- REGISTRATION STANDARDS - ISSUED September 1984 CHEMICAL & RESPONSIBLE PRODUCT MANAGER (PM) IN REGISTRATION DIVISION METHOPRENE (PM 17) METOLACHLOR (PM 23) MONO RON (PM 25) MONURON TCA (PM 25) NALED (PM 16) NAPHTHALENE (PM 16) NAPHTHALENEACETIC ACID AND ITS SALTS (PM 25) OBPA (10, 10'- OXYBISPHENOXARSINE) (PM 21) PHORATE (PM 16) PHOSALONE (PM 12) TYPE OF CHEMICAL Insecticide Herbicide Herbicide Herbicide Inset icide Insecticide Growth Regulator Fungicide Insecticide Insecticide DATE OF STANDARD & NTIS NOS. February 1982* September 1980* NTIS* PB81-123280 June 30, 1983* June 30, 1983 NTIS# PB84-166669 June 30, 1983 NTIS# PB84-158980 September 1981 NTIS# PB82-139437 August 1981 NTIS #PB82-131145 September 1981 NTIS# PB82-172271 August 30, 1984* September 1981 NTIS# PB82-131731 DATE OF GUIDANCE PACKAGE & EPA DOPCUMENT NOS. 3/31/82 9/30/80 7/7/83 7/7/83 7/6/83 11/9/81 RS-81-016 8/18/81 RS-81-006 10/27/81 RS-82-003 8/30/84 9/18/81 RS-81-010 * NTIS number not available. 39 ------- REGISTRATION STANDARDS - ISSUED September 1984 CHEMICAL & RESPONSIBLE PRODUCT MANAGER (PM) IN REGISTRATION DIVISION TYPE OF CHEMICAL DATE OF STANDARD & NTIS NOS. DATE OF GUIDANCE PACKAGE & EPA DOCUMENT NOS. POTASSIUM BROMIDE (PM 32) POTASSIUM IODATE (PM 32) SIMAZINE (PM 23) SULFUR (PM 22) SULPROFOS (BOLSTAR) (PM 12) TEMEPHOS (ABATE) (PM 16) TERBACIL (PM 25) TERBUFOS (PM 16) TERRAZOLE (PM 21) TRICHLOROFON (PM 16) Disinfectant Disinfectant Herbicide Fung icide Insect ic ide Insecticide Herbicide Insecticide Fung ic ide Insect icide September 1984 March 1984* March 1984 NTIS# PB84-212349 December 1982* August 1981 NTIStt PB82-133646 August 1981 NTIS# PB82-140641 June 1982* June 30, 1983 NTIS# PB84-210335 September 1980 NTIS# PB81-126716 June 1984* 9/28/84 3/31/84 3/30/84 12/29/82 8/10/81 RS-81-008 9/25/81 RS-81-018 6/4/82 6/30/83 9/30/80 OPP-80-525 6/28/84 * NTIS number not available 40 ------- REGISTRATION STANDARDS - ISSUED September 1984 CHEMICAL & RESPONSIBLE PRODUCT MANAGER (PM) IN REGISTRATION DIVISION TYPE OP CHEMICAL DATE Of STANDARD & NTIS NOS. DATE OF GUIDANCE PACKAGE & EPA DOCUMENT NOS. WARFARIN (PM 16) Rodent Toxicant & Anticoagulant August 1981 NTIS# PB82-140716 10/26/81 RS-81-019 ZINC PHOSPHIDE (PM 16) Rodent Toxicant and Anticoagulant June 1982 6/23/82 NTIS# PB85-102499 * NTIS number not available. 41 ------- September 1984 DATA CALL-IN - STATUS OF CHEMICALS The following chemical clusters are being processed through Data Call-in (DCI). clusters are the same as described in the Federal Register notice on November 14 (45 FR 75488) follows: An explanation of terms used to describe the status of a These , 1980 chemical is as "Letter beinq drafted": The Agency is investigating the available chronic studies and discussing the findings with registrants. "Letter issued (date)": The notice/notification or equivalent was issued to indicate existing chronic data gaps. "Decision reached": The Agency has evaluated all the responses from registrants reques- ting exemptions, waivers, commitments, offers to cost share, cancel- lations, suspensions, etc. and has issued final decisions on the data required and status of all registrations containing the chemical. The terms "chronic data-being generated" or "chronic data waiver or defer- ral" are self explanatory. "Chronic data base complete" may mean that the data were available, recently submitted, or certain data require- ments have been waived. The terms "cancelled", "suspended", and "no current registrations" mean that there are no known active registra- tions of the chemicals. The term "Defer requirements to Standard" means that the standard is planned to be developed within two years hence and the chronic requirements will be addressed in the standard. The status of these clusters and the chemicals are as follows. o Data Call-in Cluster #1 consists of insecticides used on corn, alfalfa and sorghum (1-2). Chemical Status Bufencarb Carbofuran Carbophenothion Chlorpyri fos Disulfoton Ethoprop Fensulfothion Fonofos Decision Decision Decision Decision Decis ion Dec is ion Decis ion Dec ision reached reached reached reached reached reached reached reached cancelled. chronic data chronic data chronic data chronic data chronic data chronic data chronic data base complete. being generated, base complete. being generated base complete. being generated being generated 42 ------- September 1984 DATA CALL-IN - STATUS OF CHEMICALS Landrtn (Broot) Phorate TEPP Terbuf os Trichlorfon o Data Call-in Cluster #2 consists Chemical Chlorobe nz i late Cryol i te Dimethoate Dioxothion Ethion Forraetanate hydrochlor ide Naled Tetradi f on o Data Call-in Cluster #3 consists wheat and tobacco (1-1). Aldicarb Bollex Chlordimef orm Chlord imef orm hydrochlor ide Demeton Dimilin Endr in Fenvalerate Gossyplure Grandlure Heliothis virus Methyl Parathion Monocrotophos Parathion Decision reached - chronic data being generated. Decision reached - chronic data being generated. Decision reached - Decision reached - Decision reached - of insecticides used Status Decision reached - De'cision reached - Decision reached - Decision reached - Decision reached - Decision reached - Decision reached - Decision reached - of insecticides used Decision reached - Decision reached - Decision reached - Decision reached - Decision reached - Decision reached - Decision reached - Decision reached - Decision reached - Decision reached - Decision reached - Decision reached - Decision reached - Decision reached - supended /cancel led . no added data required. chronic data base complete. on citrus and grapes (1-4). chronic data being generated. chronic data deferred. chronic data base being generated chronic data deferred. chronic data being generated. chronic data deferred. chronic data being generated. suspended/cancelled . on cotton, soybeans, peanuts, chronic data base complete. chronic data base complete. chronic data base complete. chronic data base complete. chronic data being generated. chronic data base complete. chronic data base complete. chronic data base complete. chronic data base complete. chronic data base complete. chronic data base complete. chronic data being generated. chronic data base complete. chronic data being generated. 43 ------- September 1984 DATA CALL-IN - STATUS OF CHEMICALS Permethr in Phosphamidon Toxaphene Data Call-in Cluster #4 consists Chemical Alachlor Atrazine Butylate Cyanazine Cyprazi ne Dicamba EPTC Simaz ine TCBC Data Call-in Cluster #5 consists alfalfa (H-3) - Aci f luorf en Bentazon (and sodium form) CAMA DAMA 2,4-DB Dichlofop methyl Dini tramine Dipropetryn DSMA EGT Fluchloral in Glyphosate isopropylami ne salt Metr ibuz in Naptalam Nitralin Decision Decision Dec is ion of herbic Decision Decision Decision Dec is ion Dec ision Decision Dec is ion Decision Dec ision of herbic Dec ision Dec ision Dec is ion Decision Decision Decision Dec is ion Letter i Decis ion Decision Decis ion Dec ision Dec is ion Dec ision Dec is ion reached reached reached ides used Status reached reached reached reached reached reached reached reached reached ides used reached reached reached reached reached reached reached ssued ll/ reached reached reached reached reached reached reached - chronic data base complete. - chronic data being generated - no added data required at this time on corn ( H-2 ) . - .chronic data base compl-.-te. - chronic data deferred. - chronic data being generated. - chronic data deferred. - Suspension/Cancellation. - chronic data deferred. - chronic data being gene-rait- . - chronic data deferred. - cancelled/suspended. on soybeans, cotton, peanuts and - chronic data base complete. - chronic data base complete. - chronic data being generated - chronic data being generated - chronic data being generated. - chronic data base complete. - suspended . 16/83. - chronic data being generated. - cancelled. - chronic data being generated. - chronic data basegcomplete . - chronic data base complete. - Defer requirements to standard. - cancelled . 44 ------- September 1984 DATA CALL-IN - STATUS OF CHEMICALS Norflurazon Letter issued 7/25/83. Oryzalin Decision reached - chronic data base complete. Oxyfluoren Decision reached - chronic data base complete. Pendimethal in Decision reached - chronic data base complete. Perfluidone Decision reached - No added data required. Profluralin Decision reached - cancelled. Pronamide Decision reached - chronic data being generated. Propachlor Decision reached - chronic data being generated. Vernolate Decision reached - chronic data being generated. o Data Call-in Cluster #6 consists of fungicides used on vegetables (F-3). Chemical Status Ani laz ine Calcium Cyanamide DCNA Hexachlorophene Triadimefon o Special Data Call-in Fungicide will be processed through DCI Captafol Chlorothalonil Copper (Bordeaux mixture) Copper Carbonate Copper Naphthenate Copper Oxide Copper Oxychloride Copper Quinol inolate Copper Sulfate Basic Copper Sulfate Monohydrate Dinocap Dodine Ferbam Decision reached - Defer requirements to standard. Decision reached - cancelled. Decision reached - Defer requirements to standard. Decision reached - Defer requirements to standard. Decision reached - chronic data base complete. Project consists of certain large volume fungicides which and subject to comparative risk analysis. Decision reached - chronic data being generated. Decision reached - chronic data base complete. Decision feached - chronic data not applicable. Decision reached - chronic data not applicable. Decision reached - chronic data not applicable. Decision reached - chronic data not applicable. Decision reached - chronic data not applicable. Decision reached - chronic data not applicable. Decision reached - chronic data not applicable. Decision reached - chronic data not applicable. Decision reached - chronic data being generated. Decision reached - chronic data base complete. Decision reached - chronic data base complete. 45 ------- September 1984 DATA CALL-IN - STATUS OF CHEMICALS Folpet Thiram Decision reached - chronic data being generated Decision reached - chronic data base complete o Special Data Call-in Fumigant Project consists of certain large volume fumigants which will be processed through DCI and subject to comparative risk analysis. Chemical Status Carbon disulfide Ethylene dichloride Methyl Bromide o RPAR Decision Data Call-In. Benomyl EBDC's Amobam Mancozeb Maneb Metiram Nabam Zineb Piperonyl Butoxide TrefIan Decision reached - chronic data deferred to standard Decision reached - chronic data base complete. Decision reached - chronic data being generated. Decision reached - Field monitoring study being generated Letter issued 1/83 Decision reached - Decision reached - Decision reached - Decision reached - Decision reached - Letter issued 9/30/ Decision reached - o Wood preservatives for industrial, commercial and chronic chronic chronic chronic chronic 82. chronic ine use data data data data data data (R-7) being being being being being be ing • generated . generated . generated. generated. generated. genrated. Calcium Arsenate Potassium bifluoride Pentachlorophenol Letter issued 9/28/84. Decision reached - Defer requirements to standard Letter issued 2/23/84. o Fungicides used as seed treatments (F-5) Chloronitropropane Fenaminosulf Hexachlorobenzene Dec is ion Decis ion Dec is ion reached - Cancelled/discontinued. reached - Defer requirements to standard reached - Defer requirements to standard 46 ------- September 1984 DATA CALL-IN - STATUS OF CHEMICALS o Preservatives, disinfectants, slimicides, unclassified uses (R-ll). Chemical Status Abietylamine Chromic acid Chlorobenzene Dowicil A-40 Dowicide 31,32 Hexylene glycol Lime Nitrapyrin Omad ine-sodium Potassium iodate Potassium permanganate o Insecticides used on fruit and nut trees excluding citrus and grapes (1-3) Dec ision Decision Decision Decision Decision Dec ision Decision Decision Letter i Dec ision Decis ion reached - reached - reached - reached - reached - reached - reached - reached - Cancelled Deferred Deferred Deferred Deferred Deferred Deferred Deferred • to to to to to to to standard . standard . standard . standard . standard . standard . standard . ssued 6/14/84. reached - reached - Deferred Deferred to to standard . standard Azinphos methyl Chloropropylate Cyhexatin Dormant oil Diaz inon 2-naphthol Ovex Phosmet Proparg ite Tetrasul Vendex Decision reached - chronic data base complete. Decision reached - cancelled/discontinued. Decision reached - chronic data base complete. Decision reached - no additional chronic data needed Decision reached - chronic data being generated. Decision reached - deferred to standard. Decision reached - cancelled/discontinued. Decision reached - chronic'data being generated. Decision reached - chronic data base complete. Decision reached - cancelled/discontinued. Decision reached - chronic data base complete. o Herbicides used on sorghum, rice and small grains (H-4) Barban Bromoxynil Butachlor Difenzoquat Decision reached - chronic data being generated Decision reached - chronic data being generated Decision reached - cancelled/discontinued. Decision reached - chronic data being generated 47 ------- DATA CALL-IN - STATUS OF CHEMICALS September 1984 Methazole Molinate Oxadiazon Propanil Picloram Propazine Terbutryn Triallate Decision reached - chronic data deferred. Decision reached - chronic data being generated. Decision reached - defer requirements to standard Decision reached - chronic data being generated. Decision reached - defer requirements to standard Decision reached - chronic data base complete. Decision reached - chronic data being generated. Letter issued 6/15/84. o Insecticides used on vegetables (1-5). Chemical Status Bacillus thuringiensis Malathion Methoxychlor Mevinphos Nicotine Nicotine sulfate Oxamyl Oxydemeton methyl Pirimicarb Pirimiphos ethyl Rotenone Ryanodine Sabadilla alkaloids Decision reached - biorational. Letter issued 2/29/84. Letter issued 5/23/84. Letter issued 3/28/84. Letter issued 8/30/83. Letter issued 8/30/83. Decision reached - chronic data base complete. Decision reached - chronic data being generated. Decision reached - cancelled/discontinued. Decision reached - defer requirements to standard Letter issued 12/31/83. Letter issued 11/30/83. Letter issued 8/22/83. o Herbicides used on citrus, tree fruits, nuts, and sugar cane (H-5) Ametryn Asulam Dichlobenil Hexazinone Napropamide Paraquat Decision reached - chronic data being generated. Decision reached - chronic data base complete. Decision reached - chronic data being generated. Decision reached - Defer requirements to standard Letter issued 8/30/83. Letter being redrafted. 48 ------- September 1984 DATA CALL-IN - STATUS OF CHEMICALS o Herbicides used on vegetables and tobacco (H-9). Chemical Status Bisethylxanthogen CDAA Chlorpropham Diphenamid Endothall Nitrofen Prometryn Fungicides used on plums, prunes, and walnuts, pecans, g rapes (F-2) . Letter being drafted. Decision reached - cancelled/suspended. Decision reached - chronic data base complete. Letter issued 2/21/84. Letter issued 3/12/84. Decision reached - cancelled. Decision reached - chronic data being generated almonds, apples, pears, peaches, cherries, Ammonium Polysulfide Dithianon 2,2- Dithiobisbenzothiazole Fentin hydroxide Glyodin Oxythioquinox Sodium Polysulfide Streptomycin Ziram Decision reached - suspended. Letter issued 2/28/84. Decision reached - cancelled/suspended. Decision reached - Defer requirements to standard Letter issued 2/22/84. Letter issued 3/30/84. Letter issued 11/23/83. Decision reached - chemical used as bactericide. Letter issued 2/28/84. o Herbicides used on sugar beets, beans, and peas (H-6) Cycloate Dalapon Desmedipham Diallate Dinoseb Ethofumesate MCPB Pebulate Letter issued 3/28/84. Letter issued 8/31/84. Letter issued 1/6/84. Decision reached - Defer requirements to standard Letter issued 6/13/84. Decision reached - chronic data being generated. Decision reached - suspended. Letter being drafted. 49 ------- September 1984 DATA CALL-IN - STATUS OF CHEMICALS Phenmedipham Propham Pyrazon Sodium TCA Decision reached - chronic data being generated Letter issued 1/17/84. Decision reached - chronic data being generated, Letter issued 8/30/83. o Herbicides used on drainage ditches, rights of way, forestry, and ponds (H-7). Chemical Status Acrole in 2,3,6 Trichlorobenzoic Acid Tebuthiuron Fenac Karbutilate MAMA MSMA OAMA Prometon Letter issued 12/16/83. Letter issued 9/27/84. Letter issued 9/28/84. Letter issued 8/22/83. Decision reached - cancelled/suspended. Decision reached - cancelled. Decision reached - chronic data being generated Decision reached - chronic data being generated Letter issued 8/22/83. o Insecticides used as mosquito larvicides (1-12). Kerosene Decision reached - no additional data required. o Insecticides used on livestock and domestic animals (1-6). Bomyl Bone oil Chlorfenvinphos Crotoxyphos Crufomate Dichlorvos Diphenylamine Famphur Lindane Letter issued 11/25/83. Letter issued 5/1/84. Letter issued 1/19/84. Letter issued 8/31/84. Decision reached - suspended. Letter issued - 3/22/83. Letter issued 6/6/84 Letter issued 11/25/83. Decision reached - chronic data being generated 50 ------- September 1984 DATA CALL-IN - STATUS OF CHEMICALS Muscalure Phenothi azine Piperazine dihydrochloride Tabatrex Tetrachlorvinphos o Insecticides used as fumigants Chemical 4-Chloropyr idine n-oxide Carbon Disulfide Carbon Tetrachloride Chloroform 1,3 Dichloropropene Ethylene Dibromide Ethylene Dichloride Fenamiphos Fosthietan Metam Sodium Methyl bromide Methylene chloride o Insecticides used for termite Aldr in Chlordane Dieldrin Heptachlor Letter issued 1/17/84. Letter being drafted. Letter issued 11/22/83. Letter issued 9/7/83. Letter being drafted. and nematicides (1-9). Status Letter issued 9/21/84. Letter issued 3/16/84. Letter issued 3/16/84. Letter issued 5/9/84. Letter issued 7/5/84. Letter issued 4/4/84. Letter issued 3/16/84. Letter issued 8/29/84. Letter issued 8/31/84. Letter issued 9/28/84. Letter issued 3/8/84. Letter issued 3/16/84. control (1-10). Decision reached - no additional data Decision reached - no additional data Decision reached - no additional data Decision reached - no additional data required required required required o Insecticides used on lawns, ornamentals, and forest trees (1-11) Aminocarb Fenitrothion Oftanol Letter issued 9/26/84. Letter issued 5/29/84. Letter issued 8/30/84. 51 ------- September 1984 DATA CALL-IN - STATUS OF CHEMICALS o Fungicides used on citrus (F-4). Chemical Status Thiabendazole Letter issued 8/31/84. o Disinfectants used for medical, industrial, institutional, household, veterinary, poultry, and livestock use (R-8). Formaldehyde Letter issued 9/18/84. o Plant regulators, defoliants, and desiccants used for all uses (R-10). Cacodylic Acid Letter issued 9/28/84. Cycocel Letter issued 9/28/84. Ethiofencarb Decision reached - cancelled/discontinued. Mefluidide Letter issued 9/27/84. o Herbicides used on turf (H-8). Mecoprop Letter issued 9/28/84. Terbutol Letter issued 9/28/84. o Insecticides used as domestic bug control and in food processing plants. Bendiocarb Letter issued 9/28/84. o Herbicides used for unclassified uses (H-10). Neburon Letter issued 9/28/84. o Molluscides and miscellaneous vertebrate control agents used for all uses (R-12). Methiocarb Letter issued 9/28/84. 52 ------- September 1984 DATA CALL-IN - STATUS OF CHEMICALS o Insecticides used for miscellaneous uses (1-13). Chemical Status Mobam Letter issued 9/28/84.. Special Data Call-in Groundwater Project consists of pesticide chemicals in groundwaters. o Fungicides used for a broad spectrum of uses (F-l). EBDC Amobam Letter issued 7/20/84. Mancozeb Letter issued 7/20/84. Maneb Letter issued 7/20/84. Metiram Letter issued 7/20/84. Nabam Letter issued 7/25/84. Zineb Letter issued 7/20/84. o Fungicides used on walnuts, pecans, almonds, apples, pears, peaches, cherries, plums, prunes, and grapes (F-2). 2,2-Dithiobisbenzothiazole Letter issued 5/31/84. Ferbam Letter issued 5/31/84. Ziram Letter issued 7/20/84. o Fungicides used on vegetables (F-3). Triadimefon Letter issued 7/25/84. o Herbicides used on soybeans, cotton, peanuts, and alfalfa (H-3). Diclofop methyl Letter issued 7/20/84. 53 ------- September 1984 DATA CALL-IN - STATUS OF CHEMICALS Dipropetryn DMSA Fluometuron Metribuzi n Propachlor Vernolate Letter Letter Letter Letter Letter Letter i ssued issued issued issued i ssued i ssued 6/25/84 7/25/84 6/19/84 7/25/84 7/25/84 7/25/84 o Herbicides used on sorghum, rice, and small grains(H-4). Status Chemical Bromoxynil Difenzoquat Molinate Propanil Propaz i ne Terbutryn Letter issued 5/31/84. Letter issued 5/31/84. Letter issued 5/31/84. Letter issued 5/31/84. Letter issued 7/18/84. Letter issued 7/24/84. o Herbicides used on citrus, tree fruits, nuts, and sugarcane (H-5). Ame t ry n Asulam Dichlobenil Napropamide Letter issued 7/27/84. Letter issued 6/28/84. Letter issued 6/21/84. Letter issued 7/30/84. o Herbicides used on sugar beets, beans, and peas (H-6). Cycloate Desmedipham Phenmedipham Propham Letter issued 6/22/84. Letter issued 7/30/84. Letter issued 7/20/84. Letter issued 7/18/84. o Herbicides used on drainage, ditches, rights-of-way, forestry, and ponds (H-7) MSMA Prometon Letter issued 7/25/84. Letter issued 7/30/84. 54 ------- September 1984 DATA CALL-IN - STATUS OF CHEMICALS o Herbicides used on vegetables and tobacco (H-9). Chemical Status CDAA Letter issued 7/18/84. Chlorpropham Letter issued 7/24/84. DCPA Letter issued 7/20/84. Diphenamid Letter issued 6/26/84. Endothall Letter issued 7/27/84. Prometryn Letter issued 7/18/84. o Insecticides used on cotton, soybeans, peanuts, wheat, and tobacco (1-1). Demeton Letter issued 5/31/84. Diflubenzuron Letter issued 7/27/84. Monocrotophos Letter issued 6/19/84. Phosphamidon Letter issued 5/31/84. o Insecticides used on corn, alfalfa, and sorghum (1-2). Bufencarb Decision reached - cancelled. o Insecticides used on fruit and nut trees, excluding citrus and grapes (1-3). Diazinon Letter issued 7/24/84. Dinocap Letter issued 6/28/84. Phosmet Letter issued 6/29/84. o Insecticides used on vegetables (1-5). Mevinphos Letter issued 7/23/84. Oxamyl Letter issued 5/31/84. Oxydemeton-methyl Letter issued 6/29/84. 55 ------- September 1984 DATA CALL-IN - STATUS OF CHEMICALS o Insecticides used for domestic bug control and in food pocessing plants (1-8). Chemical Status Azinphos-methyl Letter issued 7/25/84. o Insecticides used as fumigants and nematicides (1-9). Methyl Bromide Letter issued 5/16/84. 56 ------- INDEX Page Abate® see Temephos Abietylamine S #004101 47 CAS #51344-60-6 Acephate S #103301 30 CAS #30560-19-1 Acifluorfen S #114401, 114402, 114403 44 CAS # 50594-66-6 sodium salt 62476-59-9 ethyl ester 77207-01-3 Acrylonitrile S #000601 6 CAS #107-13-1 Acrolein S #000701 50 CAS #107-02-8 Alachlor S #090501 30 & 44 CAS #15972-60-8 Alar® see Daminozide Aldicarb S #098301, 110801 30,33 & 43 CAS #116-06-3 Aldrin/Dieldrin S #45101/45001 9 & 51 CAS #309-00-2—60-57-1 Aliette S #123301 33 CAS # 39148-24-8 Aluminum phosphide S #066501 33 CAS #20859-73-8 Ametryn S #080801 48 CAS #834-12-8 Aminocarb S #044401 CAS #2032-59-9 4-Aminopyridine S #069201 33 (Avitrol®) CAS #504-24-5 Amitraz S #106201, 572200 17 & 28 CAS #33089-61-1 Amitrole S #004401 33 CAS #61-82-5 Ammonium polysulfide S #076701 49 CAS #9080-17-5 Ammonium sulfamate S #005501 33 CAS #7773-06-0 Page Amobam S #014502 46 CAS #3566-10-7 Anilazine S #080811 33 & 45 CAS #101-05-3 Inorganic Arsenicals S # Multiple 31 CAS # Multiple Arsenic trioxide S #007001 6 CAS #1327-53-3 Aspon® S #079101 33 CAS #3244-90-4 Asulam S #106901 48 CAS #3337-71-1 Atrazine S #080803 33 & 44 CAS #1912-24-9 Avitrol® see 4-Aminopyridine Azinphos methyl S #058001 47 CAS #86-50-0 Bacillus thuringiensis S #006401 CAS #68038-71-1 Barban S #017601 47 CAS #101-27-9 Barium Metaborate S #011101 33 CAS #13701-59-2 Bendiocarb S #105201 CAS # Benomyl S #099101 17,18,30 5, 46 CAS #17804-35-2 Bentazon (and sodium form) 30 & 44 S #275200, 103901 CAS #25057-89-0; 50723-80-3 Benzene S #008801 6 CAS #71-43-25-2 BHC S #008901 6 CAS # mixed isomers 608-73-1 alpha 319-84-6 beta 319-85-7 gamma 58-89-9 (See Lindane) delta 319-86-8 ------- Page Page epsilon 6108-10-7 zeta 6108-11-8 eta 6108-12-9 Bidrin® see Dicrotophos Bifenox S #104301, 285200 CAS #42576-02-3 Bisethylxanthogen S #086501 CAS #502-55-6 BKLFI-2 S #046924 CAS #82010-75-1 Bollex S #118501 CAS #4175-47-7 Bomyl S #084201 CAS #122-10-1 Bone Oil S #010801 CAS #8001-85-2 Boric acid S #011001 CAS #10043-35-3 Bromacil & salts S #012301,02,03,04 CAS #314-40-9 dimethylamine bromide #69484-13-5 lithiumbromacil #53404-19-6 sodium bromcil #69484-12-4 Bromoxynil S#035301 47 CAS #1689-84-5 069104,069111 8045-21-4 ETC 2125 S #'s CAS #'s 53516-76-0, Bufencarb S #059301 CAS #8065-36-9 Butachlor S #112301 CAS #23184-66-9 Butoxicarboxime S #113001 CAS #39196-18-4 Butylate S #041405 CAS #2008-41-5 Cacodylic acid & salts S #012501 CAS #75-60-5 Sodium cacodylate 124-65-2 42 34 10 34 49 34 43 50 50 34 34 & 54 28 & 55 47 40 & 44 & 52 Cadmium S #021001, -02,-05; 012901, -02, 236200, 012903, -04,-05; 064601 CAS #'s for following compounds: anilocadmium dilactate 19651-91-3 cadmium carbonate 513-78-0 cadmium chloride 10108-64-2 cadmium oxide 1306-19-0 cadmium succinate 141-00-4 cadmium sebacate 4476-04-4 cadmium sulfate 10124-36-4 Calcium Arsenate S #013501 CAS # Calcium cyanamide S #014001 CAS #156-62-7 CAMA (Calcium ammonium methanearsonate) S #013806 CAS # Captafol S #081701 CAS #2425-06-1 Captan S #081301 CAS #133-06-2 Carbaryl S #056801 10 CAS #63-25-2 Carbot'uran S #090601 CAS #1563-66-2 Carbon disulfide S #016401 CAS #75-15-0 Carbon tetrachloride S #016501 CAS #56-23-5 Carbophenothion S #058102 CAS #786-19-6 Carboxin (Vitavax®) S #090201 CAS #5234-68-4 CDAA S #019301 CAS #93-71-0 Chloramben S #029901, -02,-03,-04, -05,-06 CAS #133-90-4 46 45 44 30 & 1 & 30 & 30 & 1 & 30 & 9 & 45 28 34 42 46 51 42 34 55 35 ------- Page Chloranil S #079301 CAS #118-75-2 Chlordane/Heptachlor chlordane S #058201 CAS #57-74-9 (cp) 12789-03-6 (tech) CAS #76-44-8 heptachor S #044801 CAS #76-44-8 Chlordecone (Kepone) S #027701 CAS #143-50-0 Chlordimeform S #059701 CAS #6164-98-3 Chlordimeform hydrochloride S #059702 CAS #19750-95-9 Chlorfenvinphos S #084101 CAS #470-90-6 Chlorobenzene S #056504 CAS #108-90-7 Chlorobenzilate S #028801 CAS #510-15-6 6 9 & 51 Chloroform S #020701 CAS #67-66-3 Chloroneb S #027301 CAS #2675-77-6 Chloronitropropane S #011302 CAS #2425-66-3 Chloropicrin S #081501 CAS #76-06-2 Chloropropylate S #026801 CAS #5836-10-2 Chlorothalonil S #081901 CAS #1897-45-6 Chlorpropham S #018301 CAS #101-21-3 4-Chloropyridine n-oxide S #069204 CAS # 6 & 9 30 & 43 30 & 43 50 47 18,30,35 & 43 11 & 51 35 46 35 47 30 & 45 49 & 55 51 Chlorpyrifos S #059101 CAS #2921-88-2 Chromic acid S #021101 CAS #7738-94-5 Coal tar S #022003 CAS #8007-45-2 Copper acetoarsenite S #022601 CAS #12002-03-8 Copper arsenate (Basic) S #271300 CAS # 16102-92-4 Copper (bordeaux mixture) S # CAS #8011-63-0 Copper carbonate S #022901 CAS #12069-69-1 Copper naphthenate S #023102 CAS #1338-02-9 Copper oxide S #025601 CAS #1317-38-0 & 1317-39-1 Copper oxychloride S #023501 CAS #8012-69-9 Copper quinolinolate S #024002 CAS #10380-28-6 Copper sulfate basic S #024401 CAS #1344-73-6 Copper sulfate monohydrate S #024402 CAS #10237-72-6 Coumafuryl see Fumarin® Coumaphos S #036501 CAS #56-72-4 Creosote S #025004 CAS #8021-39-4 Crotoxyphos S #058801 CAS #7700-17-6 Crufomate S #012101 CAS #299-86-5 Cryolite S #075101 CAS #15096-52-3 30 28 28 Page & 42 47 1 & 2 6 6 45 45 45 45 45 45 & 45 & 45 35 35 2 50 50 & 43 ------- Page Page Cyanazine S #100101 30 CAS #21725-46-2 Cycloate S #041301 49 CAS #1134-23-2 Cycloheximide S #043401 CAS #66-81-9 Cycocel S #018101 CAS #999-81-5 Cyhexatin S #101601 28 CAS #13121-70-5 Cyprazine S #100401 CAS #22936-86-3 Dalapon S #'s 028901, -2,-3,-4 CAS #75-99-0; 127-20-8; 29110-22-3 Daminozide (Alar®) S #035101 CAS #1596-84-5 Dasanit see Fensulfothion 2,4-DB S #030801 CAS #94-82-6 DBCP S #011301 9,18 CAS #96-12-8 DCPA S #078701 CAS #1861-32-1 DCNA S #031301 35 CAS #99-30-9 ODD S #029101 CAS #72-54-8 DDT S #029201 CAS #50-29-3 Deet S #080301 CAS 134-62-4 Demeton S #057601 31,43 CAS 8065-48-3 Desraedipham S #104801 49 CAS #13684-56-5 Dialifor S #078801 CAS #10311-84-9 & 44 & 54 35 52 & 47 44 49 31 42 & 19 55 & 45 9 8 35 S, 55 & 54 6 Diallate S #078801 19,36, & 49 CAS #2303-16-4 cis #17708-58-6 trans #17708-57-5 Diazinon S #057801 47 & 55 CAS #333-41-5 3,5-Dibromosalicylanilide S #077402 28 CAS #87-12-7 Dicamba S #029801, 02, 03, 36 & 44 04, 05, 06 CAS #1918-00-9; 2300-66-5; 25059-78-3; 53404-28-7 53404-29-8; 1982-69-0 Dichlobenil S #027401 CAS #1194-65-6 1,3 Dichloropropene S #029001 CAS #542-75-6 Diclofop methyl S #110902 CAS # 51338-27-3 Dichlone S #029601 CAS #117-80-6 Dichlorvos S #084001 CAS #62-73-7 Dicofol S #010501 CAS #115-32-2 Dicrotophos S #035201 CAS #141-66-2 Dieldrin see Aldrin/Dieldrin Difenzoquat S #106401 7 & 54 CAS #43222-48-6 Diflubenzuron (Dimilin) 11 & 12 S #108201 CAS #35367-38-5 Dimethoate S #035001 19,20,36 & 43 CAS #60-51-5 Dimilin S #108201 43 CAS #35367-38-5 Dinitramine S #102301 9 & 44 CAS #29091-05-2 48 & 44 & 11 & 31 & 54 51 53 36 50 36 36 ------- Page Dinocap S #036001 45 & 55 CAS #39300-45-3 Dinoseb S #'s 037511,2,3,4;037505,6 49 CAS #88-85-7; 6420-47-9; 8048-12-2; 35040-03-0; 6365-83-9; 53404-43-6; 2813-95-8 Dioxathion S #037801 36 & 43 CAS #78-34-2 Diphenamid S #036601 49 CAS #957-51-7 Diphenylamine s #038501 50 CAS #122-39-4 Dipropetryn S #104401 28,44 & 54 CAS #4147-51-7 Disulfoton S #032501 31 & 42 CAS #298-04-4 Dithianon S #099201 49 CAS #3347-22-6 2,2-Dithiobisbenzothiazole 49 & 53 S #009202 CAS #120-78-5 Diuron S #035505 36 CAS #330-54-1 Dodecylammonium methanearsonate (DAMA) 44 S #013805 CAS #53404-47-0 Dodine S #044301 45 CAS #2439-10-3 Dormant oil S # none 47 CAS # none DOwicide 31:32 S #062208, 10 47 CAS #607-12-5 Dowicil A-40 S #102801 47 CAS #38827-35-9 DSMA S #013802 44 & 54 CAS #144-21-8 EBDC S #014502, -3,-4, 20,46, & 44 -5,-6; #014601 CAS #111-54-6 (Parent); 3566-10-7; 142-59-6; 8018-01-7; 12427-38-2; 12122-67-7; 9006-42-2 (see Page amobam, maneb, nabam, mancozeb, metiram, zineb) CAS #144-21-8 EGT S #042201 CAS #2514-53-6 Endosulfan S #079401 CAS #115-29-7-1 Endothall S #'s 038901, -2,-3, -4,-5,-6,-7; CAS #145-73-3; 2536-26-7; 129-67-9; 2164-07-0; 2536-27-8 Endrin S #041601 6,20 CAS #72-20-8 EPN S #041801 CAS #2104-64-5 EPTC S #041401 CAS #759-94-4 Erbon S #028701 CAS #136-25-4 Ethiocarb S #112101 CAS #29973-13-5 Ethion S #058401 CAS #563-12-2 Ethofumesate S #110601 CAS #26225-79-6 Ethoprop S #041101 CAS #13194-84-4 Ethoxyquin S #055501 CAS #91-53-2 Ethylene dibromide S #042002 CAS #106-93-1 Ethylene dichloride S #042003 CAS #107-06-2 Ethylene oxide S #042301 CAS #75-21-8 Famphur S #059901 CAS #52-85-7 Fenac S #082601 CAS #85-34-7 49 44 36 & 55 21 & 2 & 37 & 35 & 35 & 20 & 43 & 43 28 44 6 52 41 47 40 35 21 49 2 48 48 ------- Fenaminosulf S #034201 CAS #140-56-7 Fenamiphos S #100601 CAS #22224-92-6 Fenitrothion S #105901 CAS #122-14-5 Fensulfothion S #032701 31 CAS #115-90-2 Fentin hydroxide s #083601 CAS #76-87-9 Fenvalerate S #109301 CAS #51630-58-1 Ferbam S #034801 CAS #14484-64-1 Fluchloralin S #108701 CAS #33245-39-5 Fluometuron S #035503 CAS # 2164-17-2 Folpet S #081601 CAS #133-07-3 Fonofos S #041701 CAS #944-22-9 Formaldehyde S #043001 CAS #50-00-0 Formetanate hydrochloride S #097301 CAS #23422-53-9 Fosthietan S #113301 51 CAS # 21598-32-3 Fumarin® (Coumafuryl) S #086001 37 CAS #117-52-2 Glean S #118601 38 CAS #64902-72-3 Glyodin S #043601 49 CAS #556-22-9 Glyphosate isopropylamine salt S #103601 28 & 44 CAS #38641-94-0 Page 37 & 37 & 45 & 29 & 31 & 28 & 37 & 46 51 51 42 49 43 53 42 54 46 42 52 43 Page Goal S #111601 22 CAS # 42874-03-3 Gossyplure® S #114101, 02 43 CAS # 53042-79-8, 52207-99-5 Grandlure® S #112401, 02, 03, 04 43 CAS #11104-05-5 Heliothis virus S #107301 31 & 43 CAS # none Heptachlor see Chlordane Heptachlor Hexachlorobenzene S #061001 46 CAS #118-74-1 Hexachlorophene S #044901 45 CAS #70-30-4 2 ethyl 1,3 Hexanediol (6-12) 37 S #041001 CAS #94-96-2 Hexazinone (Velpar®) S #107201 38 & 48 CAS #51235-04-2 Hexylene glycol S #068601 47 CAS #107-41-5 Hyamine 3500 S #069105 28 CAS # None Hypochlorites S #014701, 02, 03 38 CAS # for following compounds sodium 7681-52-9 calcium 7778-54-3 lithium 13840-33-0 Inorganic arsenicals 3 & 31 S #006801, 02 006901, 007001 CAS # for following compounds arsenic acid 1327-52-2 & 7778-39-4 arsenic pertoxide 1303-28-2 arsenic trioxide 1327-53-3 sodium arsenate 7631-89-2, 10103-60-3, 13464-38-5 & 35794-26-4 ammonium arsenite 58829095-1 sodium pyroarsenate 13464-42-1 lead arsenate (basic) 3687-31-8 lead arsenate 7645-25-2, 7784-40-9 & ------- Page 10102-48-4 calcium arsenate 7778-44-1 sodium arsenite 7784-46-5 copper acetoarsenite 12002-03-8 Isocyanurates S #081401,2,3,4,5,6,7 7 CAS #126-25-4 isocyanuric acid 108-80-5 isocyanuric chloride 87-90-1 potassium dichloroisocyanurate 2244-21-5 sodium dichloroisocyanurate 2893-78-9 isocyanuric dichloride 2782-57-2 isocyanuric dichloride dihydrate 515 80-86-0 ACL-66 30622-37-8 Isopropalin S #100201 38 CAS #33820-53-0 Karbutilate S #097401 50 CAS #4849-32-5 Kepone see Chlordecone Kerosene S #063501 50 CAS #8008-20-6 Landrin S #102401, 02 43 CAS #2686-99-9 Lime S #075604 47 CAS #1305-78-8 Lindane S #009001 23 & 50 CAS #58-89-9 Linuron S #035506 31 CAS #330-55-2 Magnesium phosphide S #066504, 218100 38 CAS #12057-74-8 Malathion S #0577 48 CAS #121-75-5 Maleic hydrazide S #051501, 02, 03 12 CAS #123-33-1 MAMA S #013808 50 CAS #2321-53-1 Mancozeb S #014504 46 & 53 CAS #8018-01-7 Page Maneb S #014505, 005050 46 & 53 CAS #12427-38-2 MCPA S #030501,2,3; 030553 ,-56 ,-62; 38 030563, 66; 030510 ,-11 ,-12 ,-13 ,-14 , -15,-16 CAS #94-74-6; 3653-48-3; 5221-16-9; 6365-62-4; 20405-19-0; 42459-68-7; 42459-69-8; 42459-70-1; 42459-71-2 2039-46-5; 19480-43-4; 1713-12-8; 1713-11-7; 26544-20-7; 2698-40-0 MCPB S #019201 CAS #94-81-5 49 Mecoprop S #031501 CAS #93-65-2 52 Mefluidine S #114002 52 CAS #53780-36-2 Metalaxyl (Ridomil®) S #113501 38 CAS #57837-19-1 Metam Sodium S #039003 51 CAS #6734-80-1 Methamidophos (Monitor®) S #101201 38 CAS #10265-92-6 Methanearsonates S #013802, 12 & 13 -3,-4,-5,-6,-7,-8 CAS # for following compounds calcium acid 5902-95-4 calcium methanearsonate 5902-97-6 MAMA 2321-53-1 MSMA 2163-80-6 DSMA 144-21-8 octyl ammonium 6379-37-9 docecyl ammonium 53404-47-0 Methazole S #106001 48 CAS #20354-26-1 Methidathion S #100301 38 CAS #950-37-8 Methiocarb S #100501 52 CAS #2032-65-7 Methomyl S #090301, 549400 38 CAS #16752-37-5 ------- Page Page S #042004 288700 Methoprene S #105401, 549500 CAS #40596-69-8 Methoxychlor S #034001 CAS #72-43-5 Methyl bromide S #053201 46,51 CAS #74-83-9 Methyl parathion S #053501 CAS #298-00-0 Methylene chloride CAS #75-09-2 Metiram S #014601 CAS #9006-42-2 Metolachlor S #108801, CAS #15972-60-8 Metribuzin S #101101 CAS #21087-64-9 Mevinphos S #015801 CAS #7786-34-7 Mirex S #039201 CAS #2385-85-5 Mobam S #090401 CAS #1079-33-0 Molinate S #041402 CAS #2212-67-1 Monitor® see Methamidophos Monocrotophos S #058901 CAS #6923-22-4 Monuron S #035501 7 CAS #150-68-5 Monuron trichloroacetate S #035502 CAS #140-41-0 MSMA S #013803 50 CAS #2163-80-6 Muscalure S #103201 CAS #27519-02-4 Nabam S# 014503 46 CAS #142-59-6 Naled S #034401 13,39 CAS #300-76-5 46 28,44 48 48 28,43 39 48 & 56 43 51 & 53 39 & 54 & 55 9 53 & 54 & 55 & 39 39 & 54 51 & 53 & 43 03 S #05600 055801, CAS 555-37-: #006313 Napropamide S #103001 CAS #15299-99-1 Naptalam S # 030701, 02 CAS #132-66-1 Napthalene S #055801 CAS #91-20-3 Napthaleneacetic acid 03, 04, 07, 08 CAS #86-87-3 2-napthol S #010301 CAS #135-19-3 Neburon S #012001 Neomycin sulfate S CAS #1405-10-3 Nicotine S #056702 CAS #54-11-5 Nicotine sulfate S #056703 CAS #65-30-5 Nitralin S #037601 CAS #4726-14-1 Nitrapyrin S #069203 CAS #1929-82-4 Nitrofen S #038201 CAS #1836-75-5 Norflurazon S #105801 CAS #27314-13-2 OBPA (10, 10' Oxybisphen oxarsine) S #012601 Octylammonium methanearsonate S #013804 CAS #6379-37-9 Oftanol S #109401 CAS #25311-71-1 Omadine-sodium S #088004 CAS #15922-78-8 OMPA S #058601 CAS #152-16-9 Orthene® see Acephate Oryzalin S #104201 CAS #19044-88-3 48 & 54 28 & 44 39 1, 02, 39 589300 47 52 29 48 48 44 29 & 47 7 S, 49 31 & 45 13 & 39 OAMA) 50 51 29 & 47 7 29 & 45 ------- Page CAS #87-86-5 sodium pentachlorophenate potassium " Perfluidone S #108001, 02 CAS #37924-13-3 Permethrin S #109701 CAS #52645-53-1 Perthane S #032101 CAS #72-56-0 Phenarsazine chloride CAS #578-94-9 phenmedipham S #098701 CAS #13684-63-4 #131-52-2 #7778-73-6 S #063901 Ovex S #020201 49 CAS #80-33-1 Oxadiazon S #109001 48 CAS #19666-30-9 Oxamyl S #103801 48 & 55 CAS #23135-22-0 10,10 Oxybisphenoxarsine see OBPA Oxydemeton methyl S #058702 55 CAS #301-12-2 Oxyfluorfen S #111601 22 & 45 CAS #42874-0303 Oxythioquinox S #054101 49 CAS #2439-01-2 Paraquat S #061612 13 & 48 CAS #4685-14-7 Parathion S #057501 29 & 43 CAS #56-38-2 PCNB S #056502 23 CAS #82-68-8 Pebulate S #041403 49 CAS #1114-71-2 Pendimethalin S #108501 31 & 45 CAS #40487-42-1 Pentachlorophenol S #063001, 3,4 & 46 45 44 50 & 54 Page Phenothiazine S #064501 CAS #92-84-2 Phorate S #057201 31,39 CAS #298-02-2 Phosalone S #097701 CAS #2310-17-0 Phosmet S #059201 49 CAS #732-11-6 Phosphamidon S #018201 44 CAS #13171-21-6 Picloram S #005101 31 CAS #1918-02-1 Piperazine dihydrochloride S #067401 CAS #142-64-3 Piperonyl butoxide S #067501 CAS #51-03-6 Pirimicarb S #106010 CAS #23103-98-2 Pirimiphos-ethyl S #108101 CAS #23505-41-1 Potassium bifluoride S #075203 CAS #7789-29-9 Potassium bromide S #013903 CAS #7758-02-3 Potassium iodate S #075703 32, CAS #7758-05-6 Potassium permanganate S #068501 CAS #7722-64-7 Profluralin S #106601 CAS #26399-36-0 Prometon S #080804 CAS #1610-18-0 Prometryn S #080805 CAS #7387-19-6 Pronamide S #101701 CAS #23950-58-5 Propachlor S #019101 32, CAS #1918-16-7 51 & 43 39 & 55 & 55 & 48 14 31 40 29 50 49 24 45 51 & 46 48 48 46 & 40 & 47 S, 47 45 & 54 & 55 & 45 & 54 ------- Propanil S #028201 CAS #709-98-8 Propargite S #097601 CAS #709-98-8 Propazine S #080808 CAS #139-40-2 Propham S #047601 CAS #122-42-9 Pyrazon S #069601 CAS #1698-60-8 Ridomil® see Metalaxyl Ronnel S #50301 CAS #299-84-3 Rotenone S #071003 CAS #83-79-4 Ryanodine S #071502 CAS #15662-33-6 Sabadilla alkaloids S #002201 CAS #8051-02-3 Safrole S #097901 CAS #94-59-7 Simazine S #080807 CAS #122-34-9 Sodium arsenite S #013603 CAS #7784-46-5 Sodium bentazon S #103901 CAS #50723-80-3 Sodium fluoroacetate/1080 S #075003 CAS #62-74-8 Sodium polysulfide S #006902 CAS #1344-08-7 Sodium TCA S #081001 CAS #650-51-1 S,S,S,-tributyl phospho- rotrithioate (DBF) S #074801 CAS #78-48-8 Streptomycin S #006306 CAS #57-92-1 Page 48 & 54 47 48 & 54 50 & 54 50 14 & 48 48 48 7 40 & 44 7 30 & 44 4 49 50 15 49 S .#078003 S #111501 Strobane S #020401 CAS #8001-50-1 Strychnine/strychnine sulfate S # 076901, 02 CAS #57-24-9 CAS #60-41-3 Sulfur S #077501 CAS #7704-34-9 Sulfuryl Fluoride CAS #2699-79-8 Sulprofos (Bolstar®) CAS #35400-43-2 Tabutrex S #077802 CAS #141-03-7 2,4,5-T/Silvex S #082501 CAS #93-765, 93-72-1 TCBC S #017304 CAS 1344-32-7 TCC S #027901 CAS #101-20-2 Tebuthiuron S #105501 CAS #34014-18-1 Temephos (Abate®) S #059001 CAS #3383-96-8 1081 S #075002 CAS #640-19-7 TEPP S #079601 CAS #107-49-3 Terbacil S #012701 CAS #5902-51-2 Terbufos S #105001 CAS #13071-79-9 Terbutol S #038801 CAS #1918-11-2 Terbutryn S #080813 CAS #886-50-0 Terrazole® S #084701 CAS #2592-15-9 32 40 14,48 Page 7 25 40 29 40 51 & 25 44 29 & 50 40 14 43 40 & 43 52 & 54 40 ------- Page Tetrachlorvinphos S #083701 CAS #961-11-5 Tetradifon S #079202 CAS #116-29-09 Tetrasul S #079201 CAS #2227-13-6 Thiabendazole S #060101 CAS #148-79-8 Thiophanate ethyl S #103401 CAS #23564-06-9 Thiophanate methyl S #102001 CAS #23564-05-8 Thiram S #079801 CAS #137-26-8 TOK see Nitrofen Toxaphene S #080501 CAS #8001-35-2 TPTH S #83601 CAS #76-87-9 Treflan S #036101 CAS #1582-09-8 Triadimefon S #109901 CAS #43121-43-3 Triallate S #078802 CAS #2303-17-5 S,S,S-Tributyl Phosphoro- trithioate (DBF) S #074801 CAS #78-48-8 Tributyl phosphorotri- thioite (Merphos) S #074901 CAS #150-50-5 Trichlorfon S #057901 CAS #52-68-6 2,3-6 Trichlorobenzoic Acid S #017305 CAS #2078-42-4 2,4-5-Trichlorophenol S #064204, -10,-11,-12,-14,-17,-19,-20 CAS #95-95-4 26 32 26 51 43 47 52 29 & 29 & 47 & 44 32 46 45 & 53 14,15 & 48 15 15,15,32,41 15 & 43 50 4 Page Trifluralin S #036101 27 CAS #1582-09-8 Trysben (Benzac) S #017303 7 CAS #3426-62-8; 1338-32-5 Velpar® see Hexazinone Vendex S #104601 47 CAS #13356-08-6 Vernolate S #041404 45 & 54 CAS #1929-77-7 Vitavax® see Carboxin Warfarin S #086002, 086003 41 CAS #81-81-2 sodium warfarin #129-06-6 potassium warfarin #2610-86-8 Zinc phosphide S #088601 41 CAS #1314-84-7 Zineb S #014506 46 & 53 CAS #12122-67-7 Ziram S #034805,6 49 & 53 CAS #137-30-4; 16509-79-8 ------- |