EXERCISE PLAN
FORT MEADE CWA EXERCISE
August 20, 2014
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EXERCISE SCHEDULE / TIMELINE
FORT MEADE CWA EXERCISE
AUGUST 20,2014
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FORT MEADE CWA EXERCISE
Field and Laboratory Timeline
August 20,2014
AGENDA ESC CWA EXERCISE Location: Environmental Science Center, Fort Meade, MD
August 06 and 20,2014
LABORATORY EXERCISE
Day One
Wednesday, August 20
Time: Activity:
10:00 Tailgate Safety Briefing
10:30-12:00 Set up A
Location:
Main Conference Room
Cold zone
EMSI (spill response, waste removal contractor)
Security (notify 911; deliver evac bags; block
hallways; meet emergency response team)
Skip Weisberg (Regional SHEM, spill cleanup)
Susan Shinn (Facility SHEM, observer)
Set up B Warm zone
Cindy Caporale (Agent Manager; observer)
Jeff Dodd (Facility Manager; observer)
Set up C Hot zone
John Curry (Chemist A)
Eric Graybill (Chemist B)
Kevin Poff (Clean hands; escort)
Robin Costas (Acting Manager; observer)
Set up D FGGM FD and paramedic team
12:00 -1300 Lunch Main Conference Room (Quizno's)
1300-1400 Hotwash Main Conference Room
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EXERCISE SCOPE
FORT MEADE CWA EXERCISE
AUGUST 20, 2014
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CWA 2014 EXERCISE SENARIO
Date: 20 August 2014
Purpose:
To provide practice of internal Chemical Warfare Agents (CWA) spill/emergency procedures with in the
CWA laboratory while in operation mode.
Milestones:
• May 29, 2014 - CWA 2014 Exercise Briefing Complete
• June 18, 2014 - SHEM Equipment Day Complete
• July 17, 2014 - CAO Training Complete
• July 22, 2014 - CWA Quarterly Meeting Complete
• August 06,2014 -Dry Run/Walkthrough Complete
Pre-Exercise Briefing
• August 20,2014 - CWA 2014 Exercise
Post-Exercise Debriefing
Objectives are to practice and test the following:
• Communication
• Spill response
• Spill cleanup
• Decontamination of personnel
• Notification to hospitals (notional)
• Notification of ESC security personnel
• Notification of paramedics/FGGM FD
•. Dispensing of duo dote kits and notification processes to FGGM Paramedics.
Players:
John Curry (Chemist A,)
Eric Graybill (Chemist B)
Kevin Poff (Clean hands, escort)
Cindy Caporale (Agent Manager)
Security (notify 911; deliver evac bags; block hallways; meet emergency response)
EMSI (spill response; waste removal contractor)
Jeff Dodd (Facility Manager)
Skip Weisberg (Regional SHEM, spill cleanup)
Susan Shinn (Facility SHEM, observer)
Robin Costas (Acting Lab Branch Manager, observer)
FGGM FD (Chief Bruce Smith, Chief Wray Kinsley and paramedic team)
OPP (observers)
Scenario:
The spill occurs while the CWA laboratory is conducting a through put study in G205. At approximately
10:00 am, Chemist A is receiving samples for water extraction from Chemist B. The samples were
transported by Chemist B and his escort from the primary CWA lab G102, upstairs via the CWA cart and
the elevator.
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As the samples are being removed from the secondary containment in G205 Chemist B hits the rack on
-the-lip-of-the-hood-causing-the-samples to hit the-floor,-breaking an undetermined number-of-samples-
and splashing him on the leg and foot. Chemist A determined that the spill was outside of his control
and radios for help.
Security, will notify 911 (notional), SHEM, Facility and OASQA Managers of the incident. SHEM
Manager(s) will NOTIONAL the building evacuation and notify EMSI of incident. Security will follow
through normal steps of evacuation procedures without giving out the bags and radios.
After Chemist A notifies security via radio, he then determines the need for a duo dote injection(s)
based on signs and symptoms displayed by Chemist B (notional injections will be made).
Decontamination procedures will be started on Chemist B (NOTIONAL safety showering and
decontaminating personal). Once Chemist B has been properly decontaminated, he will be transferred
via FGGM paramedics to the ambulance (notional, transportation to the local hospital). Chemist A will
also be transported alongside Chemist B.
FGGM FD/EMSI will perform decontamination of G205 and proper disposal of broken samples
containers and potential hazardous materials.
All verbal communications should be preceded with "Exercise, exercise, exercise" and ended with the
same phrase.
Chemist A radio communication:
"Exercise, exercise, exercise. Incident involving CWA in G205. Two exposures. CWA spill outside
of controls. Exercise, exercise, exercise."
Security 911 communication:
"Exercise, exercise, exercise. CWA incident at EPA Building 701 Grwing. Two exposures. CWA
spill outside of controls. Exercise, exercise, exercise."
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SAFETY INFORMATION
FORT MEADE CWA EXERCISE
August 20,2014
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Anne Arundel
EPA ESC
(Exercise Location)
701 Mapes Road
Fort Meade, MD 20755-5350
Map of Fort Meade, MD
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EMERGENCY CONTACTS AND PHONE NUMBERS
Exercise Location:
U.S. EPA ENVIRONMENTAL SCIENCE CENTER
701 MAPES ROAD
FORT MEADE, MD 20755-5350
Agency
Contact
Phone Number
Local Medical
Emergency Facility
(LMF)
Baltimore Washington
Medical Center
(17 minutes)
911 or 9-1-301-677-2117 if using
facility phone
OR
911 or 301-677-2117 via cell
Fire Department
FGGM Fire Department
911 or 9-1-301-677-2117 if using
facility phone
OR
911 or 301-677-2117 via cell
EMS
FGGM EMS
(FGGM FD)
911 or 9-1-301-677-2117 if using
facility phone
OR
911 or 301-677-2117 via cell
Police Department
EPA Facility Security
5-2800 (Facility Phone)
410-305-2800 (cell)
EPA Facility Security
EPA Facility Security
(MUST be notified as
part of call-down for
any emergency on EPA
facility grounds)
5-2800 (Facility Phone)
410-305-2800 (cell)
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DRIVING DIRECTIONS / ROUTE TO HOSPITAL (written detail):
Baltimore Washington Medical Center
301 Hospital Drive
Glen Burnie, MD 21061
410-787-4000
mybwmc.org
Starting Point:
U.S. EPA Environmental Science Center
701 Mapes Road
Fort Meade, MD 20755-5350
1. Head north on Ernie Pyle Road toward 14th Street 0.4 mi
2. Turn right at Reece Road 3.3 mi
3. Turn Left at Telegraph Road 0.7 mi
4. Merge onto MD-100 E via ramp to l-97/Glen Burnie 4.3 mi
5. Take exit 15 for Oakwood Road 0.2 mi
6. Turn right at Oakwood Road 325 ft
7. Take the first right onto Hospital Drive 0.2 mi
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Need map from mapquest.com
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SHP05.01B
Rev. 0
LABORATORY ACTIVITIES SHEET
US EPA - Region 3
| ESC ~ WHO ~ Mobile Lab
Purpose
To ensure adequate review of proposed occupational safety and health precautions, procedures and techniques for
use involving hazardous agents, equipment or operations in laboratory activities. This review applies to all
"laboratory activities" meaning EPA program activities that are conducted by EPA employees within an EPA
laboratory facility and/or mobile laboratory vehicle/trailer. (Assistance in completing this form is available from the
SHEM office).
Labwork Project / Description:
CWA Laboratory Through-Put Study
Start Date: August 20,2014
End Date: August 20, 2014
Branch: OASQA
Lab: CWA UDA
Room #: G102, G205
Point of Contact / Phone #:' John Curry / 5-2608
Person Conducting Assessment / Phone #: Susan Shinn / 5-2618
Employee's Performing Laboratory Activity: ~ Additional Sheets
1 John Curry (Chemist)
(ESAT analyst)
Eric Graybill (Chemist).
| Kevin Poff (clean hands)
| Closest Medical Facility / Phone # (Mobile Lab work only): Anne Arundel County
Physical Hazards (check all that apply)
~ None
~ Noise > 85 dBA
o Oxygen deficiency
X Sharps
~ Electrical (shock, short circuit)
o Extreme temperatures
~ Pressurized vessels
~ Autoclaves / Ovens /
hotplates
~ Electrical (static, ESD)
~ Extreme weather
conditions
X Compressed gases
~ Strenuous tasks
o Electrical (loss of power)
X Slip-Trip-Fall
X Lifting heavy objects
X Security (locked
doors, refrigerators,
confined areas)
~ Flammable liquids storage
~ Electrical hazards
~ Non-portable power tools
~ Cryogenics
~ Flammable solids
~ Power tools
~ Open flames / Bunsen
burner
~ Hand tools
o Flammable gas storage
~ Vacuum chambers or
systems
~ Other spark producing
activity
o Flame (Bunsen
burner)
X Water (specify) - STF from
shower (notional)
d Welding, brazing,
soldering
~ Explosive potential
1 X Ergonomic (design flaw)
~ Ergonomic (overexertion risk factors)
~ Ergonomic (excessive vibrations)
I X Other (specify): Human factor (stress)
Biological Hazards (check all that apply)
~ None
~ Bacteria, mold, viruses, etc
~ Insects
~ Animal
~ Vegetation
~ Mold
~ Organic dust
~ Vectors
X Medical sharps - duo
dotes
~ Viruses
~ Allergies
~ Blood components
~ Poison plants
o Recombinant DNA
~ Tissue
~ Contaminated water (microorganisms)
~ Body Fluids
~ Other (specify)
("Supervisor signature certifies that employee is up to date on all necessary monitoring and training. If controls for identified hazards
are deemed insufficient, supervisor should contact the SHEM office for consultation and further review.)
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SHP05.01B
Rev. 0
I Chemical Hazards (check all that apply)
~ None
~ Carcinogens
o Nanomaterials
X Acids / Bases
~ Perchlorates
~ Flammable liquids
~ Highly acute toxins
X Corrosives
~ Mutagens
1 ~ Flammable gases
~ Pesticides / herbicides
~ Oils
~ Teratogens
~ Flammable solids / dust
X Semi-Volatile Organics
~ PCBs
X CWA materials
~ Explosives
~ Reproductive toxins
~ Dioxins / furans
X Spill potential
~ Asbestos
~ Pyrophoric materials
~ Strong oxidizers
X Bleach
X Solvents / volatiles
X Controlled substances
~ Formaldehyde (any use)
X Transportation of
chemicals
~ OSHA regulated
chemicals (any use)
~ Highly reactive materials
~ Lead (any use)
~ Toxic metals (e.g., As,
Ba, Be, Cd)
X Methylene chloride (any
use)
~ Mercury / Hg compounds
(any use)
I ~ Other (specify)
Ionizing and Non-Ionizing Radiation Hazards (check all that apply)
XNone 1
~ Radioactive sources
~ Lasers
~ Radio frequency (RF) / Microwave energy
~ Dispersible radioactive
materials
~ Non-fissionable radioactive
materials
~ Extreme, low frequency (ELF)
1 ~ Magnetic / electric fields
~ Fissionable radionuclides
~ X-ray devices
o Infrared 1 ultraviolet sources
~ Transportation of radiological
materials
o Any atmospheric discharge of radiological
material
~ Other (specify):
Significant Laboratory Potential Hazards (check all that apply)
~ None
X Any hazardous / radiological waste generation - CWA UDA waste, bleach, spill response materials, broken glass
X Any liquid discharges that require engineering controls - shower or eyewash use, hoods,
X Storage or use of any chemicals or radioactive materials that required engineering controls - refrigerators, hoods, solvent
cabinets
X Medical Waste - duo dotes
X Other laboratory hazards related to your work (specify): communications (radios), PPE failure, safety equipment failure,
I Other Issues (Security, Notifications, etc.)
Specify: Notification to ESC Security, DO, OEC, FGGM FD, FGGM paramedics
1 Risks & Hazard Controls
o None 1
Hazard/Task:
Controls (include ventilation and PPE requirements)
Approved
(supv initials)
Absorption, ingestion,
inhalation
Gloves, safety glasses, lab coat, respirator, hood, proper training, CHP/OEP
Engineering and/or
power failures
Practice drills conducted to include shut down of operations associated with
engineering failures such as hood failure and power outages.
1 Engineering and/or
power failures
Fume hood inspections.
Engineering and/or
power failures
Hand-held detector equipment calibrations and working properly.
Training
Ensure that the operator and buddy are prepared for each operation and review the
SOP prior to beginning work.
("Supervisor signature certifies that employee is up to date on all necessary monitoring and training. If controls for identified hazards
are deemed insufficient, supervisor should contact the SHEM office for consultation and further review.)
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SHP05.01B
Rev. 0
1 Preventive Measure
When in doubt, consult the CAHO
1 Preventive Measure
Use the buddy system.
| Preventive Measures
Use secondary containers and spill trays.
H Preventive Measure
Be aware and attentive (no distractions)
| Preventive Measure
Emergency PPE and decon equipment/reagents readily available.
| Chemical Use
Proper training, CHP/OEP, user knowledge, proper PPE for the task
-
Preparer's Signature: Mail Code: • Date:
Supervisor's Approval**: Mail Code: Date:
Supervisor's Contact Number (Mobile Lab Only):
Analyst Signature Date
("Supervisor signature certifies that employee is up to date on ail necessary monitoring and training. If controls for identified hazards
are deemed insufficient, supervisor should contact the SHEM office for consultation and further review.)
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SHP05.01B
Rev. 0
(~~Supervisor signature certifies that employee is up to date on all necessary monitoring and training. If controls for identified hazards
are deemed insufficient, supervisor should contact the SHEM office for consultation and further review.)
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JOB HAZARD ANALYSIS / WORK CONTROL PLANS
Modify site-specific Job Hazard Analysis (JHA) / Work Control Plans (WCP) and the accompanying data
sheets when:
• The scope of work is changed by adding, eliminating, or modifying tasks
• New methods of performing tasks are selected
• Observation of the performance of tasks results in a revised characterization of the hazards
• New chemical, biological, radiological or physical hazards are identified
• Exposure data indicate changes in the concentration and/or likelihood of exposure
• New/different control measures are selected
When JHA/WCP are modified, related provisions in other chapters of the HASP must also be modified as
needed. The modified JHA/WCP and HASP requirements must be communicated to all affected
personnel.
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JHA/WCP-1 Modified LeyelD_PPE(SamplePrep, Lab)_
Operational Phase Task / Operation Location
Active Assessment Laboratory G205
Date(s) this JHA/WCP Conducted: August 20, 2014
Employee(s) Certifying this JHA/WCP:
Susan Shinn SHEM
Skip Weisberg. SHEM
Cindy Caporale Associate Director for OASQA
Robin Costas Acting Lab Branch Chief
Chemical Hazards:
Chemical Name / Source Concentration Regulatory Exposure Limits
GB
Sarin
None, simulated scenario
GD
Soman
None, simulated scenario
GF
Cyclosarin
None, simulated scenario
HD
Sulfur mustard
None, simulated scenario
VX
VX
None, simulated scenario
Physical Hazards:
Name of PH / Source
Ambient Heat Stress
Improper Lifting
Poor Housekeeping
Hostile Persons
Vehicle Hazards
Vehicles/Driving
Communications
Potential Hazard / Outcome
Heat rash//cramps/exhaustion/heat stroke
Back strain/abdomen/arm/leg muscle/joint injury
Slips/Trips/falls/punctures/cuts/fires
Bodily injury
Struck by vehicle/collision
Accidents/fatigue/cell phone use
Disruption of communications
Biological Hazards:
Name of BH Source Exposure Potential
NA
Control Measures Used:
Level of PPE: Modified Level D (See Section 6 - PPE)
Appropriate clothing
Closed-toed shoes
Safety eye protection
Gloves
Lab Coats
Two-way radio
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RespiratorNA
Cartridge/Canister: NA
Service Life:
Air Monitoring: PID, Altair 4X, Drager tubes, M8 and M9 papers, M256A 1 chemical agent detector kit,
AP4C, HazMat CAD
Equipment: fire extinguisher, first aid kit, heat stress monitoring equipment, bleach or other
hypochlorite decontamination chemicals, tap water sprayers, scrub brushes, decontamination tubs and
basins, 5-gallon buckets, 55-gallon drums (for decon fluids), paper towels, plastic trash bags.
Other Control Measures Used:
Buddy system required
Duodotes (notional)
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Dilute Chemical Warfare Agent
Response To Life-Threatening Or Serious Illness / Injury
• Use DuoDote (if appropriate - possibly for victim and buddy/rescuer)
• Call 9-911
• Engage alarm to alert CAHO/SHEM Manager and Supervisors
Identify the nature of the injury / illness: (Circle one)
Medical Problem:
Dizzy
Chest pain
Disoriented
Asthma attack
Unconscious
Other:
Injury:
Puncture
Cut
Fall
Stain / Sprain
Other:
CWA Exposure:
Compromised PPE
Spill / Splash
Explosion
Protective Engineering Failure
Other:
RESCUERS (Medical/Injury only):
RESCUERS (possible UDA Exposure):
• Remove to clean anteroom
• Lay patient on a clean blanket
• Remove PPE (cut away?)
• Not breathing? Establish airway
• No pulse? Administer AED
• Support until EMT Team arrives
• Remove to clean anteroom
• Lay patient on a clean blanket over a
plastic barrier sheet on gurney
• Begin decon procedure (see separate
instructions)
• Remove and bag clothes & blanket
• Replace with Tyvek garment
• Support until EMT Team arrives
Once EMT arrives be prepared to:
Supply patient name
Name of CWA patient was working with
(M)SDS for UDA / MOU / "Grab and Go" Packet
Time and frequency of DuoDote injection(s), if given
#1 Time #2 Time #3 Time
Contacts: (Check as they are completed)
UDA H&S Manager has been notified
Patient's direct supervisor notified
Form is subject to OSHA medical records regulation 1910.1020.
. Form does not replace EPA Accident / Illness / Injury Report Forms.
Rev 3 July 2014
Page 1 of2
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Dilute Chemical Warfare Agent
Response To Life-Threatening Or Serious Illness / Injury
Patient Name:.
Rescue Buddy:
UDA being analyzed:
Date: Time: Room Number:
Other Responders:
Describe:
Events leading to incident (Patient should describe or concur if she/he is able):
Hazards remaining in the room where the incident occurred:
FORM INSTRUCTIONS
• This form should be filled out every time there is a first aid response for a lab worker who is working the day
of the incident in a UDA laboratory space.
• To be filled out by "Buddy" first responder immediately after incident.
• Buddy makes two (2) copies of this report: ¦>
i. Original goes to the CAHO/CAHO on the day of the incident.
ii. One copy goes to the worker's direct Supervisor.
iii. Originator (Buddy) keeps a copy for 30 days, then passes that copy to the CAHO/CAHO for
disposition.
Form is subject to OSHA medical records regulation 1910.1020.
Form does not replace EPA Accident / Illness / Injury Report Forms.
Rev 3 July 2014 Page 2 of 2
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HEALTH AND.SAFETY PLAN (HASP)
Prepared By: Susan Shinn Date: August 20, 2014
Site Name: Environmental Science Center CWA Exercise EPA Contact: John Curry
Site Address: Fort Meade, MD
Scope of Work: (1) respond to CWA incident, set up work and decontamination zones, conduct ambient
air monitoring, document site conditions. (2) conduct site entry; perform air monitoring and
decontaminate all personnel and equipment as needed. (3) Additional tasks TBD as needed.
Background Information: this Health and Safety Plan (HASP) addresses responding to a CWA incident
located in G205 laboratory.
Responses to a CWA incident pose additional concerns and potential stresses not typically present at a
hazardous material incident. There will probably be considerable public interest and an unusual amount
of news media attention; the operations will be subject to public scrutiny. Also, there may have been
deaths and/or injuries stemming from the incident. The situation may present serious physical and
psychological threats that cause stress in the workers. Team members should be aware of the unusual
aspects of the response and potential effects on team members.
Additional Site-Specific Information:
The ESC CWA Exercise is being conducted in order to provide practice of internal Chemical Warfare
Agents (CWA) spill/emergency procedures within the CWA laboratory while in operation mode.
Hazard Assessment and Equipment Selection
In accordance with ESC's Personal Protective Equipment Program and 29 CFR 1910.132, at the site prior
to personnel beginning work, the Safety Officer and/or the Site Leader will evaluate conditions and
verify that the personal protective equipment selection outlined within this HASP is appropriate for the
hazards known or expected to exist (Refer to ESC CHP Dilute Solution Hygiene Plan).
Potential Hazards / Risks: Chemical
Simulated response, no contaminants present.
^Typical text for an actual incident: may involve nerve, blister, or blood agents, or intentional release of
toxic industrial chemicals; appropriate work zone delineation, awareness of potential chemicals and
their properties, appropriate use of PPE and air monitoring, attention to surroundings, and use of the
"Buddy System" will reduce the risk of exposure. Primary threat is through inhalation or contact with
materials; contact with any material should be minimized during all activities.
Potential Hazards / Risks: Physical (medium)
Physical hazards may include slip/trip/fall hazards. Heat stress may also be a hazard. Awareness of
potential hazards, use of the "Buddy System," and careful observation of surroundings will minimize
risks. Hostile, frightened, or panicked persons may be encountered. Awareness of potential hazards,
use of the buddy system, and careful observation of surroundings will minimize risks.
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_Potential Hazards /Risks: Biological (none)
Levels of Protection / Justification
Level B PPE with air monitoring for waste removal response, attention to surroundings, use of the
buddy system, and thorough decontamination should provide sufficient protection.
All work will be performed in accordance with the provisions of this HASP, OSHA guidelines, OASQA
SOPs, and ESC CHP.
PERSONNEL PROTECTION PLAN
Engineering Controls
Fume Hoods, real time air monitoring
Administrative Controls
8-Hour OSHA H&S refresher training, medical monitoring clearance, current respirator fit test, Level
A/B/D training, CPR/AED/l* Aid
Personal Protection Equipment
Level A/B/C/D
Description of Levels of
Protection
Level D / Level D Mod
Level C
LevelB
Level A
~ Head - Hard Hat
El Eye (Safety Glasses)
~ Hearing-Ear plugs
R1 Appropriate uniform
n Coverall (Tyvek)
^ Hand-Gloves (inner
surgical)
~ Hand-Gloves (middle)
El Hand - Gloves (outer -
surgical)
O Foot - Safety Boots
~ Foot - Over boots
~ Other - specify
~ Head - Hard Hat
0 Face (splash shield)
~ Hearing-Ear plugs
Rl Appropriate Uniform
£3 Coverall (Tyvek)
Hand-Gloves (inner
surgical)
~ Hand - Gloves (middle)
£3 Hand - Gloves (outer-
surgical)
El Foot - Safety Boots
H Foot - Over boots
El Respirator (Full Face APR)
E3 Cartridge (OV/HEPA)
0 Other (specify)
l~l Head-Hard Hat
C] Face (splash shield)
~ Hearing - Ear plugs
£3 Appropriate Uniform
CH Coverall (Tyvek)
^ Hand-Gloves (inner
surgical)
l~~l Hand-Gloves (middle)
E3 Hand-Gloves (outer-
surgical)
l~~l Foot - Safety Boots
0 Foot - Over boots
~ SCBA
n Other (specify)
I!] Head - Hard Hat
~ Face (splash shield)
~ Hearing-Ear plugs
El Appropriate Uniform
£3 Coverall (Kappler responder
CSM fully encapsulating
chemically-resistant suit)
E] Hand - Gloves (inner
surgical)
~ Hand - Gloves (middle)
^ Hand-Gloves (outer-
Butyl - integral to suit)
El Foot - integral to suit
E Foot - Over boots
I%1 SCBA-60 minute '
0 Other (specify)
Note: respiratory protection must be NIOSH CBRN certified.
SITE AIR MONITORING PROGRAM
Action Levels
These Action Levels, if not defined by regulation, are some percent (usually 50%) of the applicable PEL/REL/TLV. These
numbers must also be adjusted to account for instrument response factors.
Tasks
Action Level1
Action
Ambient Concentration
|_| Explosive atmosphere
<10% LEL
Work may continue. Consider
toxicity potential.
10 to 25% LEL
Work may continue. Increase
monitoring frequency.
>25% LEL
1 Action levels listed above do not include confined space entry work; adjustments will be required.
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-
-
-
Work must stop. Ventilate area
before returning.
~ Oxygen
<19.5% 02
19.5% to 25% O2
>25% 02
Leave area. Re-enter only with
SCBA
Work may continue. Investigate
changes from 21%
Work must stop. Ventilate area
before returning
l~~l Radiation
-
<3X background
3X background to <1 mR/hr
>lmR/hr
Continue work
Possible rad source(s) present
(normal background is 0.01-0.02
mR/hr). Continue investigation
with caution. Perform thorough
monitoring. Consult with a Health
Physicist.
Potential radiation hazard.
Continue investigation only upon
the advice of Health Physicist.
[~1 Unknown Organic
Gases/Vapors
<1 unit above background
1 to 5 units above
background
>5 to 500 units above
background
>500 units above
background
Level D, continue air monitoring.
Level C, continue air monitoring.
Level B, continue air monitoring.
Level A or evacuate affected area.
_ Specific Organics/lnorganics
13 CWA
Airborne Exposure Limit
Worker Population Limit
specific to CWA. See
attached USACHPPM
document entitled Table 1.
Summary of Chemical Agent
Air Exposure Values: Existing
Information as of 8/03/04
POC: V. Hauschild,
USACHPPM2
>AEL GPL
>AEL WPL
>AELSTEL
>AELIDLH
Level A - OR - Level D with
continuous air monitoring
Level A - OR - Level C with
continuous air monitoring
Level A - OR - Level B with
continuous air monitoring
Level A - OR - evacuate affected
area
2 USACHPPM AELs for CWA are based upon CDC values or USACHPPM derived values. OSHA, NIOSH, or ACGIH
exposure values are not applicable.
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AIR MONITORING / SAMPLING SUMMARY LOG
Work Location Instrument Readings
Location
% LEL
%02
PID (units)
FID (units)
Aerosol
Monitor
(mg/m3)
Rad Meter
(uR/hr)
Detector
Tubes
(ppm)
Other
CONTINGENCY PLAN
Response Plans
Medical - General - provide 1st Aid as trained, assess and determine need for further medical assistance.
Transport or arrange for transport after decontamination.
1 1 1st Aid Kit required
Type - standard field including
bloodborne pathogen kit
Location -
laboratory
hallways
Special 1? Aid procedure:
Cyanides on site
l~lYes Duo
If yes, contact LMF. Do
they have antidote kit?
~Yes Qno
1 1 Eyewash required
Type - standard gravity fed
Location -
laboratory
hallways
Hydrogen Fluoride on site
l~lYes 1 Ino
If yes, need neutralizing
ointment for 1st Aid kit.
Contact LMF.
Spills - in the event of a
spill or release, ensure
safety, assess situation
¦ and perform containment
and control measure as
appropriate.
a. Small spill - clean up per SDS;
Notify emergency coordinator
b. Large spill - sound alarm; notify
emergency coordinator
c. Evacuate to pre-determined safe
place
d. Account for all personnel
e. Determine if Team can respond
safely
Spill .
Response
Equipment
Location: G205
Fire/Explosion - in the
event of a fire/explosion,
ensure safety, assess
situation and perform
containment and control
measure as appropriate.
a. Sound alarm and call assistance;
notify emergency coordinator
b. Evacuate to predetermined safet
place
c. Account for personnel
d. Use fire extinguisher, only if safe
and trained
e. Standby to inform emergency
responders of materials and
conditions
Location -
laboratory
and
laboratory
hallway
Security problems - law enforcement agency involvement is likely. Personnel should assess safety of field
team, notify local police or other agencies if necessary, and assist incident commander with preventing
unauthorized persons from entering exclusion zone and contaminated persons from leaving exclusion zone.
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DECONTAMINATIONPLAN
Levels of Protection Required for Decontamination Personnel
The levels of protection required for personnel assisting with decontamination will be:
~Level A I I Level B Q Level C O Level D Q Level D Mod
Modifications include:
PPE and Monitoring Equipment Decontamination
Decontamination should be achieved through a combination of tap water rinses/showers and
thorough scrubbing using a 5% sodium hypochlorite (straight household bleach) solution.
Decontamination of human skin with bleach will not occur. A 5-minute contact time is necessary for
chemical agents. Decontamination areas must be set up upwind of the hot zone, and must be moved
if the wind direction changes. In the event of mass casualty situations, a decontamination line for
casualties should be set up separately from that for the responders. All decontamination fluids
should be bermed/containerized for disposal, and care should be taken that decontamination
equipment is itself subsequently decontaminated. The levels of protection required for personnel
assisting with decontamination will be levels A, B, C and D PPE, dependent on site conditions.
Decontamination should be conducted as follows:
1) Gross physical removal: any gross contamination should be removed (if possible) while still in
the hot zone.
2) Boot rinse: a bleach rinse should be used to prevent spreading agents during
decontamination. Level A/B required for personnel assisting with decontamination.
3) Glove rinse: a bleach rinse should be used to prevent spreading agents during
decontamination. Level A/B PPE required for personnel assisting with decontamination.
4) Full PPE decontamination: a thorough scrubbing using 5% sodium hypochlorite with sufficient
contact time is necessary. Level A/B PPE required for personnel assisting with
decontamination.
5) Full PPE rinse: a tap water rinse using hoses or water sprayers should be used to remove
bleach and neutralized agent residues. Level C PPE required for personnel assisting with
decontamination.
6) Outer Boot removal: remove decontaminated boots. Level C/mod D PPE required for
personnel assisting with decontamination.
7) Level A suit removal: personnel should remain on SCBA through this step. Level C/mod D PPE
required for personnel assisting with decontamination
8) SCBA removal.
9) Inner glove removal.
10) Field wash: personnel should wash hands and face using soap and water
A diagram of the decontamination process is shown on the following page.
Disposition of investigation-Derived Wastes
All PPE, decontamination fluids, and other potentially contaminated materials will be containerized
and stored on site pending disposition as directed by EPA or other Federal Officials.
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CHEMICAL AGENT-HAZARDS
Agent
Symbol
Hazard
Signs/Symptoms
Onset
Duration of
Persistence
Physical
Properties
Odor
Nerve
Sarin
GB
Inhalation
Absorption
Very rapid
Vapor-secs
Liq-mins to
hours
<20 hr
Colorless
liq
None
when
pure;
fruity
Soman
GD
Inhalation
Absorption
Runny nose, localized
sweating, dimness of
depending
on amount
<10-15 hrs
Colorless
liq/vap
Cyclosarin
GF
Inhalation
Absorption
vision, pinpoint
pupils, tightness in
chest, difficulty
Very rapid
Colorless
liq
Sweet,
musty,
peache
Ingestion
breathing, drooling,
cramping, tearing,
s,
shellac
V Agent
frontal headaches,
1 week if
VX
Inhalation
Absorption
involuntary jerkin
and twitching,
drowsiness, coma,
convulsions, nausea,
cessation of
Very rapid
Death -15
min
heavy
concntr. As
volatile as
motor oil.
High
Amber,
oily thick
liq
none
Vessicant
breathing, death.
-
Sulfur
Mustard
H
Inhalation
Absorption
Ingestion
Delayed 4-6
hrs to 24 hrs
Days to
weeks -
very high
Oily,
colorless
to amber
liq
Garlic,
onion
CWA-DETECTION INFORMATION
Agent
Symbol
Initial Treatment
Field Detection
Sarin
GB
Mark-1 = 2 mg Atropine and 600 mg 2-PAM CI
(Pralidoxime chloride)
Diazepam follows 3 Mark-Is.
IV effects within 1 min
IM 8 min
Ventilation and suction airway
M-8 or M-9,
APD2000/AP2C, CAM,
HazMatCAD, MiniCAMS,
DAAMS, colorimetric
tubes detection kits: M-
256A1, M18A2, pesticide
tickets
Soman
GD
Cyclosarin
GF
V agent
VX
Mustard
H
Remove agent from skin. Remove contaminated
clothes. Eyes must not be bandaged. Flush
contaminated areas but watch runoff. BAL (British
Anti-Lewisite cream) antidote = dimercaprol for
intramuscular. Tx-symptomatically.
M-8 or M-9,
APD2000/AP2C, CAM,
HazMatCAD, MiniCAMS,
DAAMS, colorimetric
tubes
Additional resources upon request: laboratory SOPs, field SOPs, SDSs, incident report form,
Environmental H&S Inspection Checklist, Environmental Protection and Sustainability Checklist, and
Summary of Chemical Agent Air Exposure Values: Existing Information as of 8/03/04 POC: V. Hauschild,
USACHPPM.
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Supporting Documents
FORT MEADE CWA EXERCISE
AUGUST 20,2014
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R3QA5001-061614
-Ultra-Dilute Chemical-Warfare-Agent (UDA) Standard Reference Material (Shipment Coordination, Receiptrlnitial
Accountability, Storage and Disposal Procedres)
Effective Date: 06-16-14
Page I of35
Ultra-Dilute Chemical Warfare Agent (UDA) Standard Reference Material
(Shipment Coordination, Receipt, Initial Accountability, Storage and Disposal Procedures)
Effective Date: 06-16-14
JUDASOPs (R3-Q/i500dseri&)(^the^ESCty ;
EPA Region III
SOP Approvals:
Preparer/Submltter
Primary Technical
Reviewer
Safety/Health Review
Quality System
Review
Name: EricGraybill
CAO
Name: Cynthia Caporale
Laboratory Branch Chief
(LBC) / Agent Manager
(AM)
Name: Susan Shinn
ESCSHEM Manager
Name: Jill Bilyeu
Quality Assurance
Officer
Signature: /s/
Date: 04-11-14
Signature: /s/
Date: 04-14-14
Signature: /s/
Date: 04-14-14
Hazard Analysis (Set A:
tachment to SOP): :
¦¦¦¦ 'v; |
LBC/AM
ESC SHEM Manager:
/s/
/s/
Verification Run: (See Appendix A)
Office of Analytical Services and Quality Assurance
701 Mapes Road
Fort Meade, Maryland 20755
The official version of this document is the paper copy located in A-205.
Is/ indicates the SOP was signed. See R3QA5001 SOP records file for details.
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¦ _ R3QA5001-061614
Ultra-DUute Chemical Warfare Agent (UD A) Standard Reference Material (Shipment Coordination, Receipt, Initial
Accountability, Storage and Disposal Procedres)
Effective Date: 06-16-14
Page 2 of35
Updates Table
Peer reviewer's initials indicate that changes meet the TNI and regulatory requirements
described in Section 9.4 in SOP R3-QA060
Responsible
Person
Date
Description of Change
Including Brief Explanation
Peer
Reviewer
Date
EG
04-11-14
Although there have been previous versions
of this SOP in draft, this is considered a New
SOP.
CC
04-14-14
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R3QA5001-061614
Ultra-Dilute Chemical WarfareAgent(UDA)Standard Reference Material(ShipmentCoordination,Receipt,Inhial
Accountability, Storage and Disposal Procedres)
Effective Date: 06-16-14
Page 3 of 35
1 Scope and Application
This standard operating procedure (SOP) describes shipment coordination and receipt procedures for
UDA standard reference material at the Office of Analytical Services and Quality Assurance
(OASQA) laboratory in Fort Meade, Maryland.
2 Summary of Method
Log-in is the procedure by which submitted UDA materials are introduced into the laboratory. The
documentation recorded during log-in of reference materials includes: agent name and ID number,
origin and quantity (concentration and volume per vial and number of vials). Upon receipt, the
accompanying documentation (chain of custody sheets and certificates), preservation and shipping
conditions are documented by manual entry into a notebook. Procedures for use of the UDA
reference solutions in preparation of calibration standards and quality control checks and other more
dilute solutions are described in SOP R3-QA5003, Procedures for Opening Ultra-Dilute Chemical
Warfare Agent (UDA) Vials and Preparation of Standards for Calibration of GC/MS.
The following cardinal principle will be followed for all procedures for dealing with chemical
agents: limit the potential exposure to a minimum by using the minimum amount of hazardous
material, utilizing the minimum number of personnel for a minimum period of time.
OASQA's primary concern is for safety and environmental stewardship.
3 Definitions
3.1 Ultra Dilute Chemical Warfare Agent (UDA1) - Reference Material of Sarin (GB),
Soman (GD), Cyclohexyl Sarin (GF), Sulfur Mustard (HD) and VX, dissolved in
solvent, at a concentration not to exceed 10 mg/L in 1,2.mL sealed glass vials. The
maximum total mass of each agent at the Environmental Science Center (ESC) is not to
exceed 100 jig at any time (per interagency agreement between EPA and DoD (Section
16).
3.1.1 The 10 mg/L solutions as received are termed "primary" solutions. Upon further
dilution, the solutions are referred to as "secondary" solutions. All procedures are the same
for both concentration levels except storage location, accountability and glove change
frequency.
3.1.1.1 Primary solutions are tracked under the initial "accountability" procedures
described in this SOP and when working with this material die outer gloves are
changed approximately every 5 minutes. Transfer and log in of unopened UDA
vials from the loading dock to the UDA laboratory refrigerators per this SOP
does not constitute working with agent and outer glove change does not annlv.
3.1.1.2 Secondary agent solutions are tracked per procedures and documented as
detailed in SOP R3QA5002. These procedures are also consistent with OASQA's
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R3QA5001-061614
Ultra-Dilute Chemical Warfare Agent (UDA) StandardReferenceMaterial (Shipment Cobrdination,R««ipt,Initial
Accountability, Storage and Disposal Procedres)
Effective Date: 06-16-14
Page 4 of35
traceability procedures as for other organic calibration standards (SOP R3QA063).
For secondary solutions outer glove changes are required as needed (when
contaminated or torn).
3.1.1.3 Primary and secondary solutions are stored separately in different refrigerators
with different access requirements.
3.1.2 The materials at the 10 mg/L concentration level are not lethal but can cause health
effects (blisters and adverse nervous system reactions).
3.2 Chemical Agent Operators (CAQsl - A chemical agent operator is anyone that works
directly with UDA solutions or unknown samples potentially containing chemical
agents. Users of UDA solutions must receive agent orientation and safety training and
comply with the accountability procedures described in this SOP and SOP R3-QA5002,
Accountability Procedures for UDA Reference Solutions. They are responsible for
documenting their use and disposal of Primary UDA standards.
3.2.1 CAOs are responsible to observe receipt of reference material at the loading
dock, transport of the material to the UDA laboratory (UDAL) and participate in
completion of the initial entries in the UDA Delivery & Accountability Assessment
Notebook.
3.2.2 All CAOs are responsible for maintaining the security and integrity of stored
and in-use UDA solutions at all times. Entry into UDA primary standard refrigerator
#1 is ultimately controlled by the physical refrigerator hasp/chain lock key.
Attachment #1, Refrigerator Access, details the "two personnel to enter" approach to
control access to agent material in the secure refrigerators. The security procedures for
UDA are included in ESC's Site Security Plan and SOP R3-QA5002.
3.2.3 CAOs are responsible to complete the UDA Accountability Standards/Reagent
Preparation Log as per R3-QA5002.
3.3 Chain of Custody (COC) - An unbroken trail of accountability that documents the
physical security of UDA reference material from origin to ESC (Attachment 6).
3.4 Laboratory Branch Chief (LBO - As a laboratory supervisor, is responsible for the
health and safety of the CAOs during all UDA procedures.
3.4.1 LBC is responsible to request and coordinate delivery of UDA reference
material from the supplier of the chemical agent This is documented in the UDA
Delivery and Accountability Assessment Notebook.
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3.4.2 Serves as backup for the Agent Manager for receipt of standard reference
materials and all other AM duties except those involving refrigerator access.
3.5 Agent Manager (AM) - Individual responsible to assure accurate accountability of UDA
agent reference materials (primary material as received) from receipt, through usage to
disposal.
3.5.1 The AM signs courier form/s for receipt of material and completes any chain of
custody forms and accompanies UDA material until secure in the UDAL.
Note: Though on the COC form, the Social Security Number of AM is not entered.
3.5.2 Routinely records the receipt and use portions of the Accountable notebook
(entry of the delivery code # and vial identification numbers).
3.5.3 Performs checks of house keeping in the UDAL and of accountability records
on days when primary UDA is used.
3.5.4 With CAOs performs physical inventories prior to each delivery and before
each new request for agent material or at least quarterly. The results of the physical
inventory and the status of use of all agent materials is documented in accountability
Summary reports. Details of the daily checks (when primary solutions are in use) and
accountability audits are included in SOP R3-QA5002, Accountability Procedures for
Ultra-Dilute Chemical Warfare Agent (UDA).
3.5.5 The AM is responsible for maintaining the security and integrity of stored and
in-use primary UDA solutions at all times.
3.5.6 Serves as backup for coordination of UDA primary solution delivery in case the
LBC is not available.
3.5.7 Holds the keys (lock-and key entry) to the primary UDA refrigerator (UDA
Refrigerator-1). Hie LBC holds a backup key in case of the AM's absence.
3.5.8 The AM is responsible to complete the UDA Primary Reference Standards
Record in the UDA Accountability notebook to document use of primary UDA
solution use in the preparation of stock reference solutions as per SOP R3-QA5002.
3.6 In case of LBC and AM absence, delivery of UDA reference material is not to be
accepted. Also, unannounced, unplanned or unscheduled shipments of UDA reference
material will not be accepted.
3.7 Accountability Summary Report - Summarizes the results of physical inventory and use
of primary UDA reference material (See R3-QA5002).
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Ultra-Dilute Chemical Warfare Agent (UDA) Standard Reference Material (Shipment Coordination, Receipt, Initial
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3.8 UDA Delivery & Accountability Assessment Notebook - A record of primary UDA
reference material receipt, as well as, usage and disposal. This notebook is retained
secure in the UDAL.
3.9 Lawrence Livermore National Laboratory. 7000 East Avenue L-091 Livermore, CA
94550 - Current source of UDA reference material.
3.10 Chemical Agent Hygiene Officer (CAHOI or ESC Safety. Health and Environmental
Manager CSHEMV Individuals responsible to ensure the UDA workplace is free of
hazards and conducts regular chemical hygiene and housekeeping inspections of work
areas and emergency equipment. Ensures that the safety training, equipment and
procedures in use in the UDA work areas are adequate. Assures UDA area hoods are
tested arid found satisfactory every month. These results are recorded in the ESC
facility safety records.
3.11 Visitors- Include instrument repair personnel and janitorial entry are only allowed into
UDAL after they have had required safety training specified by the CAHO or the
SHEM Manager for "visitors" and must be accompanied at all times while in the
UDAL. Visitor entry into the UDAL is only authorized after "End of Day" procedures
have been performed and no UDA activities are occurring in the workspace. Visitors
are not permitted to enter the UDAL whenever UDA materials are being used.
3.12 Environmental Services Assistance Team fESAT> - Contractors whose duties include
the CAO duties listed above. The contractor reports to a separate management chain
and is overseen by an EPA Project Officer. The contractor follows the procedures as per
OASQA's Laboratory Quality Manual and SOPs.
3.14 Environmental Services Assistance Team Project Officer fESAT POI - Responsible for
assuring ESAT operates within the scope of their contract.
3.15 Work Day- Refers to each day UDA material is being manipulated. The exception is for
refrigerator temperature monitoring that is required each day the operators are at work.
4 Interferences
Not applicable
5 Safety
5.1 Before beginning any procedures, refer to the Environmental Science Center (ESC)
Chemical Hygiene Plan (CHP), including Appendix A (Dilution Solution Hygiene
Plan) and ESC Occupant Emergency Plan (OEP) for general safety precautions and
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Ultra-Dilute Chemical-Warfare~Agent (UDA) Standard Reference Materia) (ShipmCTt Cobrdinatidn, Receipt^ Initial
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Effective Date: 06-16-14
Page 7 of35
required guidelines. In addition, the following special safety procedures apply to
UDA materials:
5.1.1 Reference material moved outside of the agent laboratory must be in triple
containment at all times.
5.1.2 Each agent is stored separately in secondary containment in locked refrigerators
(plastic containers with lids within trays on each shelf). The refrigerators used for
storage of UDA have lock and key, as well as, electronic locks.
5.1.3 Labels on agent vials must not be removed or defaced until the container is empty,
decontaminated and ready for disposal. If labels are accidently removed, this is to be
noted in the UDA Accountability Notebook and the AM notified.
5.1.4 UDA Safety Checklist. Beginning and End of Day (Attachment 51. Beginning of
day checks: The following items are to be checked and found satisfactory prior to any
laboratory operations in UDAL: hood operations, lab at negative pressure relative to
the hall way, decontamination solution and available containers, 2-way radio, PPE
including respirator and gloves. At the end of the day when the final section of the
checklist is completed it is placed in the UDA Safety Checklist & Hood Reports Log
in UDAL.
5.1.5 The following signs are associated with OASQA's UDA analyses:
5.1.5.1 Hallway wall directly outside of UDA storage and analyses areas:
5.1.5.1.1 "Authorized Personnel Only", "Personnel/Emergency Contacts".
5.1.5.1.2 White board: "Date & Time of Entry", "Activity (Check: UDA in Use or
Non-UDA Work)", "Air Flow Check", "Stop Sign" (posted); "Safety Start CKL"
(completed), "Safety End CKL (completed), "Stop Sign Out", "Notes".
The white board information is updated with each entry and change in activity in the
UDAL. If items do not apply they are entered as "NA".
5.1.5.1.3 Egress route.
5.1.5.1.4 Magnetic board with magnets to indicate personnel are in or out of UDAL.
5.1.5.1.5 "Stop" sign - to be posted when UDA material is being utilized.
5.1.5.2 Inside UDAL.
5.1.5.2.1 "Hood failures / power outages: Evacuate UDAL Immediately and
SHEM Manager".
5.1.5.2.2 Signs and Symptoms of nerve agent & blister exposure.
5.1.5.2.3 Personnel decontamination procedures: Tap water the liquid soap/ Repeat 3
times (minimum total of 15 minutes).
5.1.5.2.4 Results of hood tests by the ESC Contractor.
5.1.5.2.5 UDA spill cleanup procedures.
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R3QA5001-061614
Ultra-Dilute Chemical Warfare Agent (UDA) Standard Reference Material (Shipment Coordination, Receipt, Initial
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5.1.5.2.6 Refrigerator for storage of primary UDA solutions: "#1", "Restricted,
Authorized Personnel Only".
5.1.5.2.7 Refrigerator for storage of secondary UDA solutions and other standards:
"#2", "Restricted, Authorized Personnel Only", "Emergency Contacts".
5.1.5.2.8 On inside of the UDAL door: "STOP, Remove PPE & Wash Hands".
5.1.5.2.9 UDA Activities Calendar.
5.1.5.2.10 Tabular listing of instructions for UDA stock and standards preparation.
5.1.6 Physical air flow indicator- UDAL must have negative pressure relative to the hallway
(the indicator ball must not be visible from the hallway).
5.1.7 Material Safety Data Sheets (MSDS) for all the UpA reference materials and other
regents used in this SOP, are available in the ESC Library, on file with the SHEM
Manager and copies retained in the UDA Delivery & Accountability Assessments
Notebook.
5.1.8 All applicable safety and compliance guidelines set forth by the EPA and by federal,
state and local regulations must be followed during the performance of this SOP. In
addition, all procedures outlined in the ESC CHP and OEP must be adhered to. In
the event of a known or potential compromise to the health and safety of any
person, immediately stop all work and leave the UDAL, pull the fire alarm and
evacuate the building. Notify the CAHO or the SHEM Manager and other
appropriate personnel as outlined in the CHP.
5.1.9 All UDA reference materials shipping containers are to be handled with caution.
The UDA materials are hazardous (can cause non-lethal chemical burns and nervous
system disorders). Protective clothing is to include: disposable laboratory coats;
safety glasses with side shields; trousers; disposable nitrile/silver-shield gloves and
closed toed shoes. A CBRN respirator is to be available at all times in the UDAL
(For details see safety equipment listed below).
5.1.10 Upon arrival, all shipping containers must be inspected at the loading dock prior to
entry into ESC. During the inspection of each shipping container, if any of the
containers has been damaged or are leaking under no circumstances are such
containers to enter the building. The CAHO or the SHEM Manager and LBC are to
be notified immediately. Take care to protect yourself, your coworkers, equipment
and the loading dock receiving area from contamination.
5.1.11 Sample receipt procedures are to use the "buddy system", with a second person
fully trained in these procedures. All operations in using UDA materials fprimary
and secondary), must use the buddy system. In addition, as a backup to the ESC
phone system, 2-way radios are to be available at all times during UDA procedures.
Cell phones are to be turned off during activities utilizing UDA.
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R3QA5001-061614
Ultra-Dilute Chemical Warfare Agent (UDA) Standard Reference Material(Shipment Coordination, Receipt, Initial
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5.1.12 Safe Storage Procedures:
5.1.12.1 Primary UDA glass vials are to be stored in the refrigerator #1 in UDAL in
closed secondary containers within trays on each shelf.
5.1.12.2 UDA glass vials shall only be opened in UDA laboratory fume hoods.
5.1.12.3 When opened, UDA vials shall be supported by a vial rack or other physical
support to prevent tipping. Procedures for opening and use of primary UDA
material are described in SOP R3-QA5003.
5.1.12.4 Secondary UDA materials are to be stored in glass Teflon lined screw cap
vials or sealed auto injector vials in UDA Refrigerator #2 in a vial rack or
other physical support to prevent tipping within trays on each shelf.
Volumetric flasks and other glassware containing UDA material are not to
be stored in the UDA refrigerators or in the UDA hood.
5.1.12.5 Environmental samples received must be,stored in the sample receipt area of
the Environmental Science Center (ESC) Building until required for
extraction and analyses in the UDAL. The exterior of the sample containers
are screened for agent contamination.
5.1.12.6 Working batches of environmental samples must be contained in coolers
and placed on a cart or a fume hood in the UDAL.
5.1.12.7 Extracted samples must be stored in a refrigerator not containing primary,
secondary, or QA/QC standards.
5.1.13 Soill Cleanup Procedures:
5.1.13.1 In the event of an in-hood "spill" of 1 mL or less, decontamination solution
(5-6% bleach) is applied to the "spill" immediately. Operators shall use silver-shield
gloves and carefully blot the decontamination solution/spill material with absorbent
lab paper towels/pads. Contaminated paper is placed in the hood decontamination
waste container (solid waste). The hood is not to be closed but remain at the marked
level to assure no fume backwash due to the high flow velocity in the UDA hoods.
5.1.13.2 The spill area is then rinsed with water and wiped dry with laboratory
tissue/absoibent pads. This material is to be placed in the decontamination containers
in the hood.
5.1.13.3 Following spill clean-up, operators shall dispose of all contaminated PPE in
hazardous waste decontamination containers for solids in the hood.
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5.1.13.4 CAOs shall report the spill and circumstances leading to the event to the
Assistant SHEM or the SHEM Manager. Any losses of UDA material are to be
recorded in the UDA Accountability Notebook and the AM and LBC notified.
5.1.13.5 In case of larger spills or any spills outside of the fume hoods, the areas is
evacuated and then the CAHO or the SHEM Manager are called.
5.1.14 With loss of engineering controls (ventilation, hood alarms or intercom), all
personnel are to immediately remove PPE and evacuate the UDAL and call the
CAHO or the SHEM Manager.
5.1.15 Work area- The handling and use of UDA material is to be restricted to UDAL.
5.1.16 Personnel Decontamination. If suspected or actual direct contact or exposure to
UDA, wash with liquid soap and rinse with tap water. This wash and rinse cycle is to
be repeated three times using the sink or safety shower. Also, eye washes are
available in UDAL. The minimum rinse time for personnel decontamination is 15
minutes. The incident is to be immediately reported to the SHEM Manager.
5.1.17 With any minor injury or illness resulting from working in the UDAL, personnel
are to immediately decontaminate and leave the UDAL area and report to the CAHO
or the SHEM Manager. A general first aide kit is available in the hall way.
5.1.18 With any major injury nr illness ESC security are to be notified immediately.
Security personnel will notify off-site emergency personnel as appropriate and the
CAHO or the SHEM Manager. In the event of a known or potential compromise
to the health and safety of any person, immediately stop all work, remove any
contaminated PPE and leave the UDAL, pull the fire alarm and evacuate the
building.
5.1.19 Fume Hoods- Satisfactofy fume hood operations are to be verified before each use
by the CAOs (anemometer flow meter must indicate at least 100 LFM). The
operations are tested and verified by SHEM personnel monthly and immediately after
any malfunction or with significant change in equipment in the hood which could
impact air flow. The CAOs are to report to CAHO or the SHEM Manager any hood
malfunction or change in equipment in the hood that could impact air flow.
5.1.19.1 Fume hoods in UDAL are independent from other ESC ventilation
hoods and are marked at 20 cm bevond the sash as the "safe zone" from which
agent materials are not to leave the hood without decontamination. The drains in the
hood have been sealed off.
5.1.19.2 At no time during hood usage is the face or head of the CAO to
break the plane of the hood sash.
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5.1.19.3 The fume hoods are equipped with spill trays lined with paper absorbent
towels to assist in recognition and containment of spillage. Fume hoods have
auditable and visual alarms to warn of low flow.
5.1.19.4 Fume hoods shall be equipped with containers of prepared
decontamination solution.
5.1.19.5 The fume hoods are marked one sash opening level that is protective of
the operators (based on their "breathing height") and to assure the flow is sufficient to
maintain the UDAL at negative pressure relative to the hallway.
5.1.20 Gloves are to be worn while working with any UDA materials. Two layers of gloves
are required when working with UDA reference materials. An inner layer of nitrile
gloves (duct taped to the CAO's laboratory coat sleeve) and an outer layer of nitrile
gloves (configuration allows 5 minutes of work time) or an outer layer of silver-shield
gloves (allows 4 hours of work time) when working with primary solutions. For
more dilute (secondary solutions), the 2 layers of nitrile are sufficient and need only
be changed if compromised by a solution spill or tear. The inner layer of gloves are
taped to the sleeve of the lab coat (not to the coat directly) with a tab fold over at the
end to allow for easy removal.
5.1.21 UDA Safety Checklist. End of Dav (Attachment 5). End of day checks: All UDA
reference materials (10 mg/L) are to be locked in the refrigerators. All woiking
solutions and decontamination solutions and solvent materials are to be securely
capped, labeled as per SOP R3QA063 and in secondary containment All
uncontaminated solid waste is double bagged and all decontamination solutions are
covered. All hood surfaces are to be wiped with water using laboratory tissue/pads.
All locks are to be secured and all checklists and other records completed. Hood
operations are verified. If hazardous waste containers are full, the ESC waste
contractor is notified. This information is entered at the end of the day by the CAOs
in the Safety Checklist retained in the Safety Checklist & Hood Reports Log in
UDAL. The AM is to verify UDA records and housekeeping in the UDAL at the end
of each working day .
5.1.22 "Observers" of the receipt procedures, not working directly with UDA such as the
AM, SHEM Manager and LBC are to wear the same PPE as the CAOs except that
only one pair of gloves are worn. In case of an emergency, e.g., such as a spill, these
personnel are to immediately leave the UDAL.
5.1.23 Before leaving the UDAL PPE is to be removed, including safety glasses, gloves and
laboratory coats and hands are washed with soap and water.
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5.1.24 CWA specific safety training is required prior to personnel using this SOP. In
addition, to the safety training specified in the CHP, at a minimum the following
training and OASQA management approval is required:
a. CWA Awareness Training.
b. CWA Visitor Training (currently under development and this requirement is
waived until the training is available, since the content is covered in other training).
c. CWA CAO Workers Training.
6 Equipment and Supplies
6.1 Refer to the following listing of necessary equipment and supplies:
6.1.1 Loading Dock Receipt
6.1.1.1 Safety Equipment and Supplies
-Safety glasses with side shields or safety goggles.
-Disposable Tyvex laboratory coats.
-Closed toed shoes.
-Long pants.
-Gloves (double nitrile allow 5 minutes of direct work with primary UDA reference
material and nitrile silver-shield, e.g., North Silver-Shield, allows 4 hours of direct
work with primary UDA reference material).
- Respirator (NIOSH CBRN).
- 2-way radios (channel 1 is routinely used and Channel 4 is for private conversations
and Channel 3 is open and can be used by all UDA personnel to practice radio
use).
6.1.1.2 Other Equipment & Supplies, etc.
- Lab cart with containment well.
- Spill decontamination material (5-6% commercial bleach or prepared from granular
chlorine, waste container absorbent lab paper/absorbent mats).
- One 2 14 gallon bucket with screw caps.
- One 2 '/a gallon bucket with screw caps.
Note: Liquid soap and water available near loading dock in J-102.
-Photo Ionization Detector (PID), MSA Sirius, Multigas Detector with 10.6 MEV
PID (S#A3-4222).
-Listing of the supplier of the chemical agent and EPA's Office of Emergency
Management contacts.
6.1.2 UDA Laboratory (UDAL)
6.1.2.1 Safety Equipment and Supplies
-Safety glasses with side shields or safety goggles.
-Disposable Tyvex laboratory coats.
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-Closed toed shoes.
-Long pants.
-Gloves (double nitrile allow 5 minutes of direct work and nitrile silver-shield, e.g.,
North Silver Shield,allows 4 hours of direct work with primary UDA solutions.
- Duck tape.
- Respirator (NIOSH CBRN).
- 2-way radios.
-First aid kit (general) is on the wall across the hall.
- Fume hoods independent from other non- UDA ESC hoods (100 LFM) will sill
cover with Teflon to protect against corrosive decontamination solution.. Fume
hoods have auditable and visual alarms to warn of low flow.
- Spill decontamination material (5-6% commercial bleach or prepared from granular
chlorine, waste container absorbent lab towels/pads).
-Eye wash station.
-Fire extinguisher.
-Safety shower.
-Wash sink.
- Liquid soap and water available near loading dock in J-102.
-8100-8 Anemometer, Alnor Instrument Company, Niles, ILL.
6.1.2.2 Other Equipment and Supplies
-Plastic containers with lids for storage in refrigerator.
-Secondary containment trays for refrigerator.
-Secondary containment tray for hoods in UDAL.
-Utility knife or scissors.
-Permanent markers and pens.
-Laboratory cart with sealed wells.
-Four 2 lA gallon buckets with screw caps (2 for each hood, one for decon. of liquids
and one decon. of solids).
-One 2 Vi gallon bucket with screw caps for non-hazardous solid waste.
-Wipes/absorbent laboratory pais.
-Two 500 mL plastic bottles and caps for 0.5% decon. solution.
-Two locked refrigerators (Norlake Scientific) with calibrated thermistors, recording
temperature charts and card access readers secured to the wall in UDAL with locked
braided cable.
-Pasteur pipets and suction bulbs.
- Vial racks.
-Decontamination solutions.
-Waste disposal containers.
-Personnel decontamination solution (liquid soap and tap water).
-Kl-Starch indicator paper.
- Large trash bags and plastic trash can for non-hazardous material, e.g.,
uncontaminated packing material.
-Laboratory pure water polishing unit (Ultrapure De-I polishing unit).
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-500 mL plastic graduated cylinder.
- 40 ml septa vials (testing of decontamination solutions prior to disposal).
7 Reagents and Standards
7.1 Decontamination solution far spills (5-6%) - commercially available 5% sodium
hypochlorite (bleach). Unopened containers have a shelf-life of one year. Opened, in use
"Decon" solution should be replaced after 90 days or whenever the material fails a Kl/starch
test (acceptable solution give a positive blue color for chlorine presence).
7.2 Decontamination solution for UDA contaminated liquids and solids material (0.5-
0.6%) - commercially available sodium hypochlorite (bleach) diluted 1:10 with water. One
liter of this solution is prepared at the beginning of each working day and disposed of as part
of the end of day procedures. This material is used for the routine decontamination of liquid
and solids in the decontamination containers in the UDAL hoods.
7.3 Ultra Dilute Chemical Warfare Agent reference material (UDA) - will be provided in
sealed glass vials. Each vial contains 1 mL of one agent in solvent at 10 mg/L. Ten vials are
provided for each agent (maximum quantity of 100 fig for each agent).
7.4 Hexane (pesticide grade) or Methylene Chloride - used for final screening of liquid waste
decontamination solutions prior to final disposal. This procedure is described in SOP R3-
QA5003.
8 UDA Reference .Material Preservation and Storage
8.1 UDA Refrigerators - After UDA reference materials are received, they are stored at
4±2°C, secured by electronic and lock & key access control and dedicated to UDA
materials only. Security includes key pads in the 2nd floor G-wing hallway for UDAL
and a lock and key and electronic entry refrigerator system. Access to the UDA
Reference Material laboratory is limited to authorized staff only (signs posted).
8.1.1 The refrigerator electronic system retains a record of entry in both refrigerators.
The AM output this record every two weeks for entry in the Refrigerator Entry &
Temperature Log. The CAOs and AM also indicate on a handwritten sheet the reason
for entry (Attachment 7). The temperature charts are changed by the CAOs each
week (charts are initialed and dated when installed and when removed). The charts
and reason for entry sheets are retained in the Refrigerator Entry & Temperature logs.
8.1.2 Log book entries are checked each week by the AM per the procedures in R3-
QA5002.
8.1.3 Refrigerator#! contains the UDA primary solutions (10 mg/L) of reference
material as received from the supplier of the chemical agent. The AM controls the
physical lock and key access to the UDA refrigerator #1. Both the AM and COs must
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be present to access this material and this material is tracked to the 1 uL amounts in
the UDA Accountability Notebook. Refer to Attachment 1 for a listing of personnel
having access to the UDA refrigerators.
8.1.4 Refrigerator #2 contains more dilute secondary solutions. The more dilute
solutions in Refrigerator #2 are tracked by the AM using procedures in R3-QA5002.
In addition, the CAOs document preparation of secondary solutions using traceability
procedures as for other non-UDA calibration materials used in the OASQA
laboratory (R3QA063, Laboratory Notebooks). The later documentation is retained
in the UDA Accountability Standards/Reagent Preparation Logs (ESAT and EPA).
8.2 UDA reference materials are stored in a refrigerator dedicated to reference material
separate from any sample or reagent storage.
9 Quality Control
9.1 The temperature of the refrigerators used for storage of the UDA reference materials
must be maintained at 4±2°C. The refrigerators have a built in temperature recording
charts. The charts are checked by the CAOs each work day and if the temperature is or
has been out of ranee, the refrieerator/s are not opened and the LBC and ESC
SHEM Manager are notified.
9.2 Delivery coordination, COC records, certificates of analyses and other records
accompanying UDA reference material are also stored in the UDA Delivery &
Accountability Assessments Notebook (Section 17). Use of all UDA primary agent
solutions is also recorded in this notebook.
9.3 Accountability inventories, summary reports and AM Checklist serve as an ongoing
check on the process and documentation and the reports from these assessments are
retained in the UDA Delivery & Accountability Assessment Notebook. Details on
accountability procedures are included in SOP R3-QA5002, Accountability Procedures
for Ultra Dilute Chemical Warfare Agent (UDA).
9.4 Procedures for use of the UDA reference solutions in preparation of secondary solutions
such as calibration standards and quality control checks are described in SOP R3-
QA5003.
10 Calibration and Standardization
10.1 Initially, and annually, the CAOs calibrate the refrigerator temperature devices
against a reference thermometer as per SOP R3QA065, current revision.
10.2 Since UDA reference material is not shipped with a temperature hlank a working
thermometer to check receipt temperature is not necessary.
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11 Procedure
11.1 Coordination of shipment and receipt of UDA reference material
11.1.1 The LBC is the point of contact for the initiation of all shipments of standard
agent material to the ESC. Deliveries of UDA reference material are carefully planned
and scheduled. A courier service is employed for the delivery of UDA reference material
from the supplier of the chemical agent to assure delivery is completed and the UDA
material is secure. Unannounced, unplanned or unscheduled shipments are not accepted
and are to be returned to the supplier of the chemical agent. In case of LBC and AM
absence, delivery of UDA reference material is not to be accepted. Communications with
the supplier of the chemical agent are retained in the UDA Delivery and Accountability
Assessment Notebook.
11.1.2 The LBC coordinates receipt and log-in via E-mail messages to the facility
management, ESAT project Officer (if applicable), CAOs, AM and CAHO or the SHEM
Manager.
11.1.3 The LBC or designee notifies facility management to instruct ESC security staff
to bar entry of the carrier to the ESC compound until notification of the LBC, AM,
CAHO or the SHEM Manager or personnel trained for receipt of this material. ESC
employees attempting to use the J-wing elevator or the transport route corridor should be
asked to wait until the UDA material is moved through the area.
11.1.4 The Agent Manager assumes LBC's agent delivery coordination related duties in
cases of the LBC's absence.
11.2 ¦ Shipment receipt and transport to UDAL hood
11.2.1 The.CAOs complete the beginning of day portion of the Safety Checklist
(Attachment 5). This includes collecting of the necessary materials for receipt of the
UDA reference material at ESC's loading dock. If problems are detected the LBC is
notified immediately so that corrective actions can be completed prior to agent arrival.
11.2.2 All UDA reference material shipments are to be delivered to the OASQA loading
dock within a secure compound area (security fence, electronic lock entry control and
surveillance cameras).
11.2.3 Shipments are by courier delivery services which tracks the location during
transport.
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11.2.4 Each shipping container must be visually inspected to ensure that they are sealed
and show no evidence of tampering, damage or leaks. Shipping seals must be Unbroken.
The package should be scanned using the portable PID to detection of solvents.
11.2.5 The CAHO or the SHEM Manager is to be called immediately if there Is any
evidence of these conditions. If these conditions exist, no material is to enter the
ESC and decontamination will be performed under the supervision of the CAHO or
the SHEM Manager or designee.
11.2.6 If the reference material containers are acceptable to inspection, the material is
signed for by the AM.
11.2.7 The acceptable containers are placed in a welled laboratory cart dedicated for this
purpose (stored in UDAL) and moved from the loading dock directly to the J-wing
elevator (J-114 will not be entered) and down the 2nd floor E-wing corridor and placed
in the ventilation hood in UDAL and opened.
11.3 Opening shipping container and log-in of material
11.3.1 Once in the ventilation hood in UDAL, remove and set aside all documentation
associated with the reference material, including certificates from the supplier of the
chemical agent, COCs, etc. This material will be retained in the UDA Delivery &
Accountability Assessment Notebook. The package should be scanned using the portable
PID to detect any spilled solvents that could indicate broken UDA vials.
11.3.2 Uncontaminated packaging material including vermiculite, Styrofoam spacers
and ice pack from each shipping container is to be left in the shipping container and
double bagged in polyethylene bags, labeled as "Non-hazardous Waste" and this will be
disposed of routine non-toxic material for incineration.
11.3.3 If the UDA reference nackaging material has been contaminated the CAHO or
the SHEM Manager are to be notified regarding disposal.
11.3.4 Each vial of material arrives with a unique identification number and this
information is recorded in the UDA Accountability Notebook by the AM. The
information entered is verified and initialed/dated by the AM and CAOs.
11.3.5 The vials are placed in plastic containers with press seal lids and in turn placed in
secondary containment plastic trays in side the reference material refrigerator. Paper
towels are used to cushion the glass vials. A separate plastic container is used for each
agent (labeled with agent name). Nerve agent is always stored separately from blister
agent material.
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11.3.6 The AM notifies the supplier of the chemical agent of any discrepancies in number
or amount of reference material (completes Shipment Condition Report form and sends
that and a signed COC form to the supplier of the chemical agent).
11.3.7 The chemical agent supplier's COC and condition form are critical documents that
must be complete and accurate (See Attachment #3, #4 and #6). These forms and other
documents that arrive with each UDA shipment are retained in the UDA Delivery &
Accountability Notebook in UDAL.
11.3.8 The CAOs complete the end of day portion of Safety Checklist
11.4 Decontamination of contaminated liquids and solids
11.4.1 All materials exposed directly to UDA material are to be decontaminated (placed
in decontamination solution in marked 2 Vi gallon screw capped containers in the UDAL
hoods). In case of breakage during shipping or during unpacking, that contaminates a large
amount of packing material, evacuate the area and notify the CAHO or the SHEM Manager
and the AM.
11.4.2 Separate decontamination containers are available in the hood in UDAL for solid
material and liquid material. Containers are filled 1/8 full with 0.5-0.6% bleach solutions prior
to use. Organic material such as solvents, should not be added at more than 1/3 the capacity of
the container at one time (to avoid excess heat). "Decon" containers are not to be filled more
than 4/5 full. Full containers are closed, marked full and labeled for waste disposal.
11.4.3 Materials for emergency decontamination will be routinely brought to the loading
dock when UDA reference materials are received.
11.5 The CAO's complete the end-of-dav portion of the Safety Checklist (Attachment 5).
11.6 The AM verifies of accountability documentation, security and good house keeping in the
UDA Delivery and Accountability Assessments Notebook as per R3-QA5002. The LBC serves as
backup for all AM duties except those involving refrigerator access.
12 Data Analysis and Calculations
12.1 The Agent Manager signs the carrier form and COC forms.
12.2 The AM initiates completion of the Chemical Warfare Agent 1° Standard Receipt form and the
Chemical Agent Shipment Condition Report Form. Subsequent tracking of usage of UDA material
is described in SOP R3-QA5002.
12.3 The AM sends copies of the completed condition form, COC, carrier form, receipt form,
certificate of analysis and MSDS sheets are sent to the provider, the EPA Office of Emergency
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Management, OASQA's Director, the ESC SHEM Manager, the LBC and the provider of the
Agent. Hardcopy documentation is retained in the UDA notebooks as listed in Section 17.1 of
this SOP.
13 Method Performance
13.1 Before approval of these procedures a hazard analysis is performed by the CAOs, Agent
Manager, LBC, CAHO or the SHEM Manager (results summarized in Attachment #2), who sign off
on this assessment.
13.2 Initially before approval of this SOP, an acceptable verification run of the procedures is
performed by the CAOs with sign off by the CAOs, Agent Manager, LBC and SHEM Manager
(approval signatures are included per Appendix A).
13.3 To help assure safe operations and the accuracy of the hazard analysis and verification run, all
changes to this SOP will be reviewed and approved in writing by the signers of this SOP.
13.4 To help control distribution and accuracy of this SOP each copy will be assigned a unique
identifier.
14 Pollution Prevention
14.1 As this SOP is performed, the CAOs should consider steps to reduce the use and generation of
hazardous chemicals and record this information for future revisions of the SOP.
14.2 Resource Management: Water conservation. Laboratory personnel should be mindful of water
consumption, and whenever possible, employ practices that minimize water use.
15 Waste Management
15.1 Expired or other unneeded UDA reference material is removed to the hood and placed in the
decontamination solution.
15.2 Decontamination solution containers that are full are labeled for disposal as hazardous waste.
This is documented in the UDA Accountability Notebook.
15.2.1 Waste Type Code: D002, pH >12.5 solution,
MD02, decontamination of CWA material.
Estimate Amount of Waste per shipment: 6 L
Describe any Treatment: No treatment of the waste is performed in the laboratory.
15.2.2 The decontamination solutions, will be of three types. One is from decontamination of
spills. Another is form the decontamination of liquids and the third is from
decontamination of solids (includes solid materials such as gloves and paper
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pads/absorbent material). Solid and liquid wastes are to be kept separate and in
addition to the MD02 and D002 codes, are to be labeled "Liquid Decon" and "Solid
Decon".
15.3 Uncontaminated solid waste such as packing material will be marked as (
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16.1 US EPA Region ID, OASQA Laboratory Quality Manual.
16.2 US EPA Region III, ESC Occupant Emergency Plan (OEP), Emergency Procedures
and Hazardous Materials Spills.
16.3 US EPA Region III, ESC Chemical Hygiene Plan (including Appendix A, Dilute
Solution Hygiene Plan).
16.4 R3QA063, Laboratory Notebooks.
16.5 R3-QA5002, Accountability Procedures for Ultra Dilute Chemical Warfare Agent
(UDA).
16.6 R3-QA5003, Procedures for Opening Ultra-Dilute Chemical Warfare Agent (UDA)
Vials and Preparation of Standards for Calibration of GC/MS.
16.7 R3-QA5004, GC/MS Analysis of Ultra-Dilute Chemical Warfare Agent (UDA)
Standards and Samples.
16.8 National Environmental Laboratory Accreditation Program (NELAP) Standards.
16.9 Introduction to the Chemical Agent Dilute Solution Hygiene Plan, Midwest Research
Institute, NEMC-01, July 2007.
16.10 General Operating Procedures for Chemical Agent Dilute Solution, Midwest
Research Institute, NEMC-02, July 2007.
16.11 Design and Operating Requirements for Chemical Agent Dilute Solution
Laboratories, Midwest Research Institute, NEMC-03, July 2007.
16.12 Laboratory Ventilation and Engineering Controls for Chemical Agent Dilute Solution
Laboratories, Midwest Research Institute, NEMC-04, July 2007.
16.13 Training for Chemical Agent RDTE and Ultra-Dilute and RDTE Dilute Solution
Laboratories, Midwest Research Institute, NEMC-05, July 2007.
16.14 Storage Requirements and Hazard Communication for Chemical Agent Dilute
Solution Laboratories, Midwest Research Institute, NEMC-06, July 2007.
16.15 Physical Security Plan for the Chemical Agent Dilute Solutions Laboratories,
Midwest Research Institute, NEMC-07, July 2007.
16.16 Procedures for Control of Locks, Keys, and Combinations Designated for Use in the
Chemical Agent Dilute Solution Facilities, Midwest Research Institute, NEMC-08,
July 2007.
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16.17 Accountability Procedures for Ultra-dilute Chemical Agent Solutions and RDTE
Dilute Solutions, Midwest Research Institute, NEMC-09, July 2007.
16.18 Interagency Agreement (IAA) between EPA and DoD dated November 22,2006.
16.19 ECBC Guidelines for Managing a Research, Development, Testing, Evaluation
(RDTE) Laboratory (September 2005).
16.20 Region 1, General Operating Procedures for NERL-Dilute Chemical Agent
Laboratories, 3/20/08, Revision 0, DRAFT.
16.21 R3QA065, Calibration and Maintenance of Laboratory Support Equipment.
16.22 Appendix E of "Final Programmatic Environmental Impact Statement: Transportable
Treatment Systems for Non-Stockpile Chemical Warfare Material, Volume III,
February 2001. "The Sources, Fate, and Toxicity of Chemical Warfare Agent
Degradation Products", Nancy B. Munro, Sylvia S. Talmage, Guy D. Griffin, Larry C.
Waters, Annetta P. Watson, Joseph F. King, and Veronique Hauschild.
16.23 Site Security Plan, Environmental Science Center.
16.24 ESC Occupant Emergency Plan (OEP).
16.25 Draft Standard Analytical Protocol for Extractable Semivolatile Organic Compounds,
September 30,2008 (Provided by CS and the EPA Working Group).
16.26 Study Specific Instructions for Phase I Multi-laboratory Validation of Procedures to
Measure Semi-volatile Agents in Environmental Samples using Gas
Chromatography/Mass Spectrometry (GC/MS), Draft for Review, Rev. 0.5,
November 21,2008.
16.27 Study Plan for Multi-laboratory Validation of Procedures to Measure Semi-Volatile
Chemical Warfare Agents in Environmental Samples using Gas Chromatography /
Mass Spectrometry (GS/MS), October 23,2008.
17 Tables, Diagrams, Flowcharts and Validation Data
17.1 Notebooks
Note: The most current version of the following notebooks is referenced. The most
current listing of OASQA quality system documents is maintained by the QAO.
SNB 327 (B), UDA Delivery & Accountability Assessment Notebook (UDAL). This
includes: records of coordination of UDA deliveries from supplier of chemical agent, carrier
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deliver receipts, COC, chemical agent supplier provided records (such as purity and volume
statements & MSDS sheets) and accountability checks and summary reports.
SNB 354 (A), UDA Refrigerator-1, Primary UDA Solutions, Entry & Temperature Log.
SNB 326 (B), UDA Refrigerator-2. Secondary UDA Solutions, Entry & Temperature Log.
SNB 353 (A), UDA Refrigerator-3, UDA Sample Extract Solutions, Entry & Temperature
Log.
SNB 328 (A), UDA Safety Checklist (Beginning/End of Day) & Hood Reports Log (UDAL).
This contains daily safety checklist forms completed by the CAOs (before work starts and
end of day checks), as well as, any notes on hood operations.
SNB 330, UDA SGPs and Quality System Documents (UDAL). This contains UDA SOPs,
Laboratory Quality Manual, ESC CHP and other references).
SNB 332, Instrument Maintenance, Purelab Deionization Polishing Unit.
PNB 199, UDA Accountability/Standard/Reagent Preparation Log (UDAL).
PNB 192 (A), UDA Sample Preparation Log
17.2 Attachments
Attachment #1: Refrigerator Access (UDAL G-102)
Refrigerator #1, Primary UDA Solutions:
Physical key for lock/kev:
Primary- AM.
Backup# 1- LBC.
Electronic refrigerator card and code:
EPA CAOs.
Refrigerator #2, Secondary UDA Solutions:
Physical key for lock/kev:
Primary- EPA CAO #1.
Backup# 1-AM.
Electronic refrigerator card and code:
LBC.
EPA CAO #2 & ESAT CAO.
Refrigerator #3, Secondary UDA Solutions (Sample & Spiked Sample Extracts):
Physical kev for lock/kev:
Primary- EPA CAO # 1.
Backup#!- AM.
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Electronic refrigerator card and code:
LBC.
EPA CAO #2 &ESATCAO.
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Attachment 2: Hazard Analysis:
Hazard Analysis
Preoperational Checklist and Transfers In and Out of Hood
Operation description
Location(s)
identified
within
operation
Effects of hazards on the operation
Risk®
Assessment
Code (RAC)
Recommended actions to reduce the hazards
I
Resulting
RAC
code
Checking hood function
Lab
Due to malfunctioning, magnahelic
indicates acceptable flow when it
is out of range.
Lab staff exposed.
Low
Check face velocity with hanging vane velometer
prior to use.
I
Low
I
Checking hood function
Lab
Due to malfunctioning magnahelic or
hood alarms, hood failure occurs
without warning.
Lab staff exposed.
Medium
Perform routine maintenance on hoods.
Check face velocity with hanging vane velometer.
Test hood alarms periodically and perform needed
maintenance.
Low
Glove check
Lab
Improper check, operator misses hole
in gloves.
Exposed staff initiates the emergency
response alarm.
Low
100% glove check.
Use two pair of gloves.
Low
i
Transfer in or out of a
hood
Hood/Lab
Spill outside or inside of ventilation
control.
Staff exposed to agent
Initiate alarm.
Medium
Use of secondary containers and spill trays.
Caution and focus on task at hand (no distractions).
Verification run SOP steps prior to working with
chemical agent
PPE worn as specified.
Emergency PPE and decontamination
equipment/reagents available.
\
"Buddy" verifies safety procedures and is available to
assist with emergency response.
Low
-------
R3QA5001-061614
Ultra-Dilute Chemical Warfare Agent (UDA) Standard Reference Material (Shipment Coordination, Receipt, Initial Accountability, Storage and Disposal
Procedres)
Effective Date: 06-16-J 4
Operation description
Locations)
identified
within
operation
Effects of hazards on the operation
Ri9ka
Assessment
Code (RAC)
Recommended actions to reduce the hazards
1
Resulting
RAC
code
Preparing & using
decontamination
solutions
HoodA_ab
Splatter or spifl of caustic such as
solid or liquid sodium hydroxide,
HTH, sodium carbonate.
Inhalation hazard.
Dermal hazard.
Respiratory distress.
Skin irritation.
Caustic bums (delayed) on operator's
hands, arms* face, and eyes.
High
PPE—goggles or face shield worn over safety
glasses with side shields, gloves, lab coat, or
coveralls with rubber apron.
Weigh caustics in hood.
Attentiveness to task (no distractions).
Purchase Clorox or HTH in small containers.
Use hood while pouring Clorox or scooping solid
HTH.
Wear respirator when scooping HTH solids out of
large container. Requires training and testing for
fit.
I
Medium
I
Transferring waste to
processing room
Lab
Operator drops waste container in lab.
Exposure to residua) agent solution.
Splatter of caustic.
Burns to lab personnel (delayed).
Medium
Double-bagging (standard practice).
Caution (e.g., check to make sure there are no
obstructions In path, etc.).
Use lab cart to transport items.
Low
-------
R3QA5001-0616I4
Ultra-Dilute Chemical Warfare Agent (UDA) Standard Reference Material (Shipment Coordination, Receipt, Initial Accountability, Storage and Disposal
Procedres)
Effective Date: 06-16-14
Operation description
Location(s)
identified
within
operation
Effects of hazards on the operation
Risk0
Assessment
Code (RAC)
Recommended actions to reduce the hazards
' |
Resulting
RAC
code
Human Factors:
Stress associated with
working with CA
(especially when
performing operations
for the first time) may
result in accidents.
Ergonomics issues may
result in accidents.
Working in a hood
creates unnatural
posture and
movements. Laboratory
work may require
repetitive movements
resulting in tiring of
specific muscles,
cramping, and skeletal
fatigue. Accidents
have resulted from an
indifferent attitude,
failure to use common
sense, or failure to
follow instructions.
Hoods and
laboratory
Chemical agent exposure, injury, and
property damage.
Trips, slips, foils, spills, etc.
High
Ensure that the operator and buddy are prepared for
each operation, and review the SOP prior to
beginning work.
Any questions about the procedure should be
adequately addressed and answered prior to
beginning the operation.
If the operator or buddy is not feeling well, do not
start the operation. Think about what is required
of the procedure and ensure that the operator and
buddy can complete the tasks required.
Give some thought to ergonomics. Adjust body
posture for comfort Strive to maintain movements
within the hood that match natural movements. If
fatigue or cramping occurs, schedule breaks as
part of the activities (at an appropriate time).
Always be aware of what your coworkers are doing
in your immediate area because you can be a
victim of their mistakes. Do not hesitate to point
out to fellow workers if they are engaging in
unsafe practices or operations. Variations in
established procedures, including changes in
quantities or reagents, may be dangerous. If
necessary, consult the Chemical Agent Hygiene
Officer.
Low
Recovery from
engineering and/or
power failures.
Hoods and
operations
in UDAL
Chemical agent exposure and injury
High
Practice drills conducted to include shut down of
operations associated with engineering failures
such as hood failure and power outages.
1
a All risk assessment codes were determined only after considering human factors such as indifferent attitude, failure to use common sense, and failure to
follow instructions.
-------
R3QA5001-061614
Ultra-Dilute Chemical Warfare Agent (UDA) Standard Reference Material (Shipment Coordination, Receipt, Initial Accountability, Storage and Disposal
Procedres)
Effective Date: 06-16-14
Page 28 of 35
Attachment 3: Example Chemical Agent Shipment Condition Report Form:
SHIPMENT CONDITION REPORT:
A. SHIPMENT NUMBER:
B. NUMBER OF STANDARD VIALS FOR THE DAY:
C. SHIPMENT RECEIVED BY:
D. DATE/TIME RECEIVED BY:
E. PHYSICAL CONDITION OF SHIPMENT: Note any unacceptable conditions
F. TRANFER DOCUMENT NUMBER(S):
Form Retained in UDA Delivery & Accountability Assessment Notebook SNG 327.
-------
R3QA5001-061614
Ultra-Dilute Chemical Warfare Agent (UDA) Standard Reference Material (Shipment Coordination, Receipt, Initial
-Accountability, Storage and Disposal Procedres)
Effective Date: 06-16-14
Page 29 of 35
Attachment #4: Example UDA Accountability Form
Chemical Warfare Agent 1° Standard Receipt
Shipping tracking numbers: Fed Express #
LLNL#
AM
CAO
CAO
Physical condition (good / broken):
Date Received: / / Received by:
Lot number (If multiple Lots note #s in comments column): ;
Volume (e.g., 1.2 mL): Concentration: "Mix": GB & GF at 10 ug/mL and GD & HD at 5
ug/mL and "Vx" at 10 ug/mL or indicate below in comments column)
COC Form competed & copy returned (Y/N):
i^llgg
LLNL = Lawrence Livermore National Laboratory.
Reviewed by: Date:
Form Retained in UDA Delivery & Accountability Assessment Notebook SNB 327.
-------
R3QA5001-061614
Ultra-Dilute Chemical Warfare Agent (UDA) Standard Reference Material (Shipment Coordination, Receipt, Initial
Accountability, Storage and Disposal Procedres)
Effective Date: 06-16-14
Page 30 of 35
Attachments: Safety Checklist (Beginning & End-of-Day)
Date
CAO's Initials
Time
i m*m
iTut^SK
ZF&f-.'y
ix/NiWf
8Kffiiggsi
kY/NJiM
Labs at negative pressure relative to the hallway and no hood alarm/s?
Hood flow > 100 LFM via anemometer and hood emergency purge tested?
Both 5% and and fresh 0.5% solution available and Dreoared?
PPE including gloves and respirator available?
•
2-way radios available and operational?
UDA refrigerator temperatures 4 + 2° C?
"Stop" sign posted on the outside of UDAL door and cell phones turned
off while in UDA laboratories?
White board in hallway updated with activity, etc?
For re^pfofdelivery of UDA reference material, prepare welled cart
available with all material per checklist on cart, if applicable?
II. End of each working dav - prior tn ending all work with Af>
rV UDA in UDAL:
Date
CAO's Initials
Time
wr-
•r" • •
Labs at negative pressure relative to the hallway and no hood alarm/s?
Hood flow ok (> 100 LFM via anemometer) and hood emergency purge tested?
UDA refrigerator temperatures 4 + 2° C?
Log books complete?
All solutions capped and properly labeled and in 2ndary containment?
All primary solutions locked in Refrigerator-1.
Work surfaces washed down and decon as needed?
Extra (-50 mL) 0.5-0.6% decontamination solution added to decon.
buckets and solid material is cover by decon. solution?
Decontamination solutions and containers closed and no leaks?
Hood sashes at hood level mark (open be protective of CA breathing
zone and to assure lab negative pressure to hall)?
UDA refrigerator locked (key, electronic and wall cable)?
Work area, clean? All PPE removed and appropriately disposed and wash
hands before leaving UDA Labs?
If waste pickup is needed, has call been placed for pickup?
If applicable, move "Stop" sign to the inside of UDAL door?
All access/egress doors locked?
This completed checklist placed in the UDA Safety Checklist & Hood
Report Log in UDAL, if applicable?
2-way radios off and charging?
White board in hallway updated with activity, etc?
For receipt of delivery of UDA reference material, prepare welled cart
available with all material per checklist on cart, if applicable?
Form Retained in UDA Safety Notebook SNB 328.
-------
R3QA5001-061614
Ultra-Dilute Chemical Warfare Agent (UDA) Standard Reference Material (Shipment Coordination, Receipt, Initial
Accountability. Storage and Disposal Procedres)
Effective Date: 06-16-14
Page 31 of 35
Attachment 6: Example COC Form
MATERIEL COURIER RECEIPT
MWi CCHIWXG&Wiil! M3
ECB-CB^t-OP-CO-8079-0260
MOKWNO:
" "WUWeVBTWJOaiBIT
Shawn HBinleto, "
oeman*
C.lfettiv.Lm.L*ms%CA 925422
umrAooasTcajaB
oaowMVWUMMrr imbumii iiiihib lUtFMrfw
SHIPMENT DESCRIPTION
t4M»
Ottjtror
aewiMMOtt
«Md
SHIPMENT TRANSFERS
1
lOnri
10ea 1 ml rials
GB/Hex EPA cfira (flute
tmt
kQCiiuiV
2
tOrrf
10»1 ri rials
ritdinB4-1J
GDMex EPA uXna (Bute
nawnm
TttMWftAB.FW.Mii
OQm.QRiOCQCNIMd
3
10ml
10»a 1ml vials
**0*4-13
QRHw EPA uBra Arts
WUIIM
imii rnrnvmiTn
4
VM
lOea imlvto
rid#* 4-13
VMPAEPAufeacSuto
secck>
lOQUttVWMflA
MtfnWOCW)
5
1M
1fes 1ml rials
rial ft 4-13
KDftfexEPAiAadbfe
o*M.ttAGcasntt
6
1
-------
R3QA5001-061614
Wa^e^gwl (UIM)^totodj^ferace Material (Shipment (^rdjnation, Receipt,.Initial.
Accountability, Storage and Disposal Procedres)
Effective Date: 06-16-14
Page 32 of 35
Attachment 7: Reason for UDA Refrigerator Entry
UDA Refrigerator # Page: 1 of 1
Date
Time
Initials
Reason for Entry
.
¦
¦
-------
R3QA5001 -061614
Ultra-Dilute Chemical Warfare Agent (UDA) Standard Reference Material (Shipment Coordination, Receipt, Initial
Accountability.Storage andDisposalProcedres)
Effective Date: 06-16-14
. : Page 33 of 35
Forms Retained in UDA Refrigerator #1, #2 and #3 logs (SNB 354,326 and 353).
Appendix A
-------
R3QA5001-061614
Ultra-Dilute Chemical Warfare Agent (UDA) Standard Reference Material (Shipment Coordination, Receipt, Initial
Accountability, Storage and Disposal Procedres)
Effective Date: 06-16-14
Page 34 of 35
DCN: R3-OA5(fl)l.«
ElTiictiua Date: Jolv 25.2lKW
Pagd 1 of 27
SOP Approvals:
Pi«pa rtrtfid raiihur
IT*fraj(r> Verliolral
llcvttttiir
MVIj.'HttUb Review
Vitality Syrian
Ktvfc^
Name: r.-vtph Slaytmi
'r*ehnleol Olrvttec'
Agon Munagnr lAM)
Hm:: f.yittllij Cojiu&ik
LubomUry Dreneb Chief
*
SjgDJlUl
Dttc:
^^CxkfL-f
• g
SHSM Miugcr:
Nim.-: darlc", Weithcrfi
Cbtmlcal A»tal Onerator:
Hams: Jo» Curry
JRynalafe;
!OJiL—Lmm
Cbexiital Agtttt Operator.
Xaruc KfNfcus Rdebirvosf
(iif.immtitiii SavkK
AnWubmcv "Hijgn tfJiAf) J
igaoUrt' //3
LUC:
Njiret; Cyolhia Cqamk
Signalling 6wr__
TMbalcd DJitflnrfAM:
ESC SI1EM Manger;
None; Chariot Vebibci^ ;
Signals
P»u>: "ifi?
Name Siiayiuii
Siguo'
H,.7
2f?KH5«
Ultra-Dilute ChLTnluil Warfare Agent (UDA) Standard tiefVrenceMaterial
cuiiictiUilivii iwxinili'tl during tog-in ol'reference nuiicrwls indmics: .lgcnl rum* and 11) number,
itri^in and qiiwijiij (LonvcawrtHm and vqbimc pa via] and mw>t»r«f vtajs). Upon receipt. Utc
dcr-ompunyioe docunwniulion (chain of uiJlody sheets and cuttfteaux). preservation mitl skipping
ooiKlilions utc toeumcniiii liy rruiuaal cutty into a nuiefouik. Fnxbdures For ote«f (he UDA
reference xidytivni in fwupar^iiin ofiMtfrrution standards and quality uwuro) checks and ottwr more
dilute «iUnions arc desenbed In SOP R3QAS(K)3.0, GC'MS Analysis i»f UDA.
Appendix B
-------
R3QAS001 -061614
Ultra-Dilute Chemical Warfare Agent (UDA) Standard Reference Material (Shipment Coordination, Receipt, Initial
Accountability, Storage and Disposal-Procedres)
Effective Date: 06-16-14
Page 35 of 35
CWA GENERATED WASTE
Procedural W«ste
obftjttai
ed
!
Ul
1
at
Gttsdtt) k
«H 1
UMMb
-HHl
_2
•
Uqsta*etaab
tafatgg*
>fU
n^n
itettBMOKkflifiMdttiaflbtfMtnaMtam
-------
criMiif
SIGMA-ALDRICH
tlgma-aldrichxotn
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
Version 4.0 Revision Date 12.03.2010
Print Date 26.04.2010
GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product name
Product Number
Brand
Company
Telephone
Fax
Emergency Phone #
!Dichloromethane?
"" > ,\"Le '
D65100
Sigma-Aldrich
Sigma-Aldrich
3050 Spruce Street
SAINT LOUIS MO 63103
USA
+18003255832
+18003255052
(314) 776-6555
2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
According to Regulation (EC) No1272/2008
Carcinogenicity (Category 2)
According to European Directive 67/548/EEC as amended.
Limited evidence of a carcinogenic effect
Label elements
Pictogram
Signal word
Hazard statements)
H351
Precautionary statement(s)
P281
Hazard symbol(s)
Xn
R-phrase(s)
R40
S-phrase(s)
S23
S24V25
S36/37
Other hazards - none
Warning
Suspected of causing cancer.
Use personal protective equipment as required.
Harmful
Limited evidence of a carcinogenic effect
Do not breathe gas/fumes/vapour/spray.
Avoid contact with skin and eyes.
Wear suitable protective clothing and gloves.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Synonyms Methylene chloride
Formula
Molecular Weight
Sigma-Atdrfcti • D65100
CH2CI2
84,93 g/mol
Page 1 or 6
-------
CAS-No.
EC-No.
Index-No.
Classification
Concentration
Methylene chlori
de
75-09-2
200-638-9
602-004-00-3
Care. 2; H351
Xn. Carc.Cat.3, R40
>= 99,9 %
For the full text of the H-Statements mentioned in this Section, see Section 16.
4. FIRST AID MEASURES
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If Inhaled
If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
S. FIRE-FIGHTING MEASURES
Suitable extinguishing media
Il6e water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special protective equipment for fire-fighters
Wear self contained breathing apparatus for fire fighting if necessary.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions
Use personal protective equipment Avoid breathing vapors, mist or gas. Ensure adequate ventilation.
Environmental precautions
Do not let product enter drains-
Methods and materials for containment and cleaning up
Soak up with inert absorbent material and dispose of as hazardous waste. Keep In suitable, closed
containers for disposal.
7. HANDLING AND STORAGE
Precautions for safe handling
Avoid inhalation of vapour or mist.
Normal measures for preventive fire protection.
Conditions for safe storage
Store in cool place. Keep container tightly closed In a dry and well-ventilated place.
Heat sensitive. Store under Inert gas.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Personal protective equipment
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with
multi-purpose combination (US) or type AXBEK (EN 14387) respirator cartridges as a backup to
engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Slgma-Aldrlch • D66100 Page 2 of 6
-------
Hand protection ~~
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the
standard EN 374 derived from H
Handle with gloves.
Eye protection
Face shield and safety glasses
Skin and body protection
Choose body protection according to the amount and concentration of the dangerous substance at the
work place.
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at
the end of workday.
I
9. PHYSICAL AND CHEMICAL PROPERTIES ~
Appearance
Form
Colour
Safety data
pH
Melting point
Boiling point
Flash point
Ignition temperature
Lower explosion limit
Upper explosion limit
Vapour pressure
Density
Water solubility
Partition coefficient
rvoctanol/water
Relative vapour
density
Evaporation rate
10. STABILITY AND REACTIVITY
Chemical stability
Stable under recommended storage conditions.
Conditions to avoid
Heat, flames and sparks. Exposure to sunlight.
Materials to avoid
Alkali metals, Aluminum, Strong oxidizing agents, Bases, Amines, Magnesium, Strong acids and strong bases.
Vinyl compounds
liquid
colourless
no data available
97 "C - lit.
39,8-40'C-lit
no data available
556,1 °C-
12 %{V)
19 %(V)
470,8 hPa at 20,0 °C
1.687,3 hPa at 55,0 °C
57,99 hPa at 25 CC
1,325 g/mLat25 *C
slightly soluble
logPow: 1,25
2,93
- (Air e 1.0) .
0,71
Slgma-Aldrtdi • 065100
Page 3 of 0
-------
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides, Hydrogen chloride gas
11. TOXICOLOGICAL INFORMATION
Acute toxicity
LD50 Oral - rat -1.600 mg/kg
Remarks: BehavioraliAtaxia.
LC50 Inhalation - rat - 52.000 mg/m3
Skin corrosion/Irritation
Skin - rabbit - Skin irritation >24 h
Serious eye damage/eye Irritation
Eyes - rabbit - Mild eye irritation - 24 h
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
Genotoxicity in vivo - rat - Oral
DNA damage
Carcinogenicity
Carcinogenicity - rat - inhalation
TumorigeniciCarcinogenic by RTECS criteria. Endocrine:Tumors.
This product is or contains a component that has been reported to be possibly carcinogenic based on its IARC,
ACGIH, NTP, or EPA classification.
Limited evidence of carcinogenicity in animal studies
IARC: 2B - Group 2B: Possibly carcinogenic to humans (Methylene chloride)
Reproductive toxicity
no data available
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Potential health effects
Inhalation May be harmful if inhaled. May cause respiratory tract irritation.
Ingestion May be harmful if swallowed.
Skin May be harmful if absorbed through 6kin. May cause skin irritation.
Eyes May cause eye irritation.
Signs and Symptoms of Exposure
Sigroa-Aldrlch - D65100
Page 4 of 6
-------
uKniorumeinane'is metabolized In the body producing carbon monoxide which increases and sustains
carboxyhemoglobin levels in the blood, reducing the oxygen-carrying capacity of the blood., Acts as a simple
asphyxiant by displacing air., anesthetic effects, Difficulty in breathing, Headache, Dizziness, Prolonged or
repeated contact with skin may cause:, defatting, Dermatitis, Contact with eyes can cause:, Redness, Blurred
vision. Provokes tears., Effects due to ingestion may include:, Gastrointestinal discomfort Central nervous
system depression, Paresthesia., Drowsiness, Convulsions. Conjunctivitis., Pulmonary edema. Effects may be
delayed., Irregular breathing.. Stomach/intestinal disorders, Nausea, Vomiting, Increased liver enzymes.,
Weakness, Heavy or prolonged skin exposure may result in the absorption of harmful amounts of material.,
Abdominal pain
Additional Information
RTECS: PA8050000
12. ECOLOGICAL INFORMATION
Toxicity
Toxicity to fiGh LC50 - Plmephales promelas (fathead minnow) -193,00 mg/l - 96 h
NOEC - Cyprlnodon varlegatus (sheepshead minnow) -130 mg/l - 96 h
Toxicity to daphnia EC50 - Daphnia magna (Water flea) -1.682,00 mg/l - 46 h
and other aquatic
invertebrates.
Persistence and degradabiWy
no data available
Bloaccumulatfve potential
rto data available
Mobility In soil
no data available
PBT and vPvB assessment
no data available
Other adverse effects
no data available
13. DISPOSAL CONSIDERATIONS
Product
Observe all federal, state, and local environmental regulations. Contact a licensed professional waste
disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn
in a chemical Incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.
14. TRANSPORT INFORMATION
ADR/RID
UN-Number 1593 Class: 6.1 Packing group: III
Proper shipping name: DICHLOROMETHANE
IMDG
UN-Number. 1593 Class: 6.1 Packing group: III EMS-No: F-A, S-A
Proper shipping name: DICHLOROMETHANE
Marine pollutant No
IATA
UN-Number 1593 Class: 6.1 Packing group: III
Proper shipping name: Dlchloromethane
15. REGULATORY INFORMATION
Siemfr-AMrich • 065100
PegeS of 6
-------
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
16. OTHER INFORMATION
Text of H-code(s) and R-phrase(s) mentioned In Section 3
Care.
H351
Xn
R40
Carcinogenicity
Suspected of causing cancer.
Harmful
Limited evidence of a carcinogenic effect.
Further Information
Copyright 2010 Sigma-Aldrich Co. License granted to make unlimited paper copies for internal use only.
The above Information is believed to be correct but does not purport to be all inclusive and shall be used
only as a guide. The information in this document is based on the present state of our knowledge and is
applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee
of the properties of the product Sigma-Aldrich Co., shall not be held liable for any damage resulting from
handling or from contact with the above product. See reverse side of invoice or packing slip for additional
terms and conditions of sale.
Sigma-Aldrich - D68100 Page 6 of 6
-------
Mixtarc l>thal Ncr>*c Agcnt (GB) in Hrxflne1
Rtvbctf: IIJodo2007
Section I ¦ General Information
Matnfklmr"t Addrraa:
t* S. Army Edgewood Ctieimcal Biological Center (EC8C)
ATTN. AMSMWKOWS-CR
Aberdeen Proving Ground, MD 2(910-5424
Bmuten Pboae 4I0-4J6-4411 or 4414. Monday through Friday during the tain of t.OQ AM to 4:J0 PM SOT
Chtfsfcil XmMfJfGpmpyl mrthylphotpKonaflooHdm md Itauhc
Tradi nuM and lywajrwn
GBin solvent
CASARMOB
KOTH Dilute GB
Cbenteo) PamHjn Mixture erf a fluorinated orgeteptosphontf compound aed flammable tohrot
Molecular Format* GRx C* H*. F Oj P
Molecular VbnBtda Beauer: CJIu
NFPA 704 Signet:
sp««ui >o
Section II - Ingredients
fotrcdkiitt/Nunr OB & Hexaoe
Ctoreatntcoa: Dilute 09 coacentmtons vary Go® 2.0 mgofCB pet (nfflUitet o! Hexuie taO.Otl uaof CB per
oiltiltteroTKcxnc
Section in -
Apprmof* and Odor of CBi Coloriett liquid Odorless in pure form.
if OTB; Due to low coocentraaoni of agent fa> Dihn OB the fearful^ physical piopartUi given aw d»a of die
Hsane, for eddrtiocal OB pmpertes refcr to the neat GO M5DS.
Appttfiict and Odori Cdortn* liquid with a mid sotvest type odor.
Boiling Point <9 760 mm Hf? 69" C
Vnpor Pressor* (mm Hg)i IM J5T
Vapor Density (Air^l); 2.97
Spcdftc Gravtty (H|tHl>: 046
Viscosity: 0 >1 mPai @ICC
Motctohr Weight (g/mof)j 36.18
frcedof/MtfUog Point: ^?"C
Section IV • Fire and E»plorfon Data
NOTt OB Is not known to be flammable. Inflxrnaitaa given for fife and explosion data cornea fro® the
flammable solvent, Hcxane
FUxb Point: -7*P(-22Vt
1-ower Biphrfva Limb;
Upper IfiplPiUa UmU: 7 9%
AateliaWton Tmpwrtow 4J7*P(22JfcC)
Gcffagtriifciog Media: For am ill fires. use dry chemical powder, CO«end alcoHol-femtant foam Water may bo
ineffective Avoid on of c*ftagulthiBg maihodi thai will can** sploshtng or spreading of tolveat
Special Fire Fighting Procedure*: All pmoo* not engaged in eftimgulshJcg (be Are fhould be immctistely
evacuated from tfre area Ftres should be contained to prevent spteading to uncotrttatkd areas. Whenrapnafintto
a fire alarm In bufldbigs or anas containing lotvemi, me-Aghting personnel should wear fkafl firefighter protective
dotting (flame resistant) doting lire fighting and ftre rescue operations ReipJretory protecnoo h required Positive
pressure, fbU-fiee piece, NIOSH-eppfoved self-contained breathing apparatus (SCBA) will be worn where thtre it
danger efacygen dtfctency end *bat disteftd by flit fift chief or chemical atodtrt/mideta "«"
Airborne Exporare Umtti (ABL|:
Mixture GB-Hcx Page 2 of 10
-------
For GB*:
Worker Poptriatien limit STtLTj-min TWA' 1 IDLlf1 Qvwsl PopulaliM I.imH
j (WPL) l-hr TWA' m^ra' mgrtn* (GPI.) 12-hr TWA :
I _____ mg/m'
1 PpftEOj 0.0001 I 0.1* _ | $.§M9?L
1 These value? can be found in the DA, Office ofthe Assistant Secretory, Installations end Environment memo,
subject Implementation Guidance Policy for New Airborne Exposures Lhmtt for OB, OA, CD. GF. N'X. H, HD.
and HT, lg June 2QM
7 To date, the Occupational Safety cr.d Health Admio!iUauan(OS1tA)have not promulgated o permiialMe exposure
concentration for OB.
Per Hiust:
Thresh eld Lhrrit Vahiv (TLV): The TLV for hexane is W ppm or ISO myW us an eight-hour time*wvighted ,
¦veragt ("WAV
PEL: 3U0 ppm a 1800 mg/m TWA.
Thi* mixture ir sot listed by tfet International Agency for Research on Cancer (1ARCX Atoericen Conference cf
Oimiimwtttal Induiriai ttygiemd* fACGIH). Occupational Safety and Health Administration (OSHA), or National
Toxicology Program (NT?) as a carcinogen
N
The onlxhtre should be treated at a poisonous and fl ernmsWe liquid Personnel should avoid contact with I he
rondure and use appropriate of protective dothuig eod equipment
.lOTE; There b presently no toxicity dtto foi the mrxture sA«iteltlag (NOTE;
Miosis ii oot an eatly sign of fi^tid sfcfn exposure. This is only mm for exposures that include contact with airborne
vapor wlthihe eyes hi cases of nerve agent exposure not involving vapor contact with the eye* miosis way br one
ofthe Us! effects to occur. In such coses, the dotage* of ltqmd exposure which produces miosis sre not sJgmficanrty
different than lethal dosesj
Toxicity Vehwi:
Vaoor dahalationJOmlart*
ECHO (Mild) • I mg-minW ;
BC1S0 (Seveto)1*n 23 mg-tntftfn'
LCIS0 * 35 m^min/m4
Yumffci
BCtSO (Threshold) * " 1700 mg-minW
BClSd (Sevete)'» S000
LClSO** l20Ct>Tng-mln,/m
HmW rrmpwntwn)
BD50- IOOOm^7&kgniBn
LDS> * 1700 mgrto kg man
1 Estimataa far iahalation vapor exposure ere based o& a mnmte vdume IMV) of 15 IHeta end a 1 minute exposure
The effective dOMges wilt mcrcese with lower MV aod decrease for a higher MV The coneenttstioMime profik| la
described by the toxic load model (C*t-4:) The toxie lood exponent (n) u 1.5 The dosc-response corva is very
steep
* ttacd oo recent studies estimates for this value, dosage may actually be 0 4 mgHriattn*
* Severe effects may atorachide death
4 Pmostnel are masked.
* Valuea for percutaneous vapor are for moderate temperatures (g$ 'f cod beJovf) The effective doaayes for hot
temperatures (85 *F ood above) will be leu by at least a fhctor of 2
' Ttuesbold ttftrt to a slight ChB Inhibition
Eroergeitcy and Vlrsl AM Procedares:
NOTE: When seeking medlceletteottott, inform meificalpersonod that this is in orgaoophosphonia mixture.
Vapor Exposure: Immediately leave aim uf camaminjrHon. Vapor expoied oervi ageert casualties «bou!d he
decostaninaMd by removing ell clothing m a dean air environment and shampooing or rtnsing the hair to prevrnt
vapor off gassing
liquid Skin Kxpasur*; Leave area of contamination aa qutckty at possible. Remove clothing in a clean eir
environment «ad wash ihoddn aurfrcc and hair in warm or hot water at least three times The rapid physical
removal of a chemical agent b essential Scrubbing of exposed skin with a stifTbrush or bristles is discouraged,
because skin damage may occur and may increase absorption of agent. Use liqwd soap (dispose of container alter
use and replace), copious amounts of water, and mHd to moderate friction whh & single-use sponge or wasbctoft in
the fint acd second washes TfctftinJ waihshoaM be a rinse with copious amounts of warn or hot water.
Shampoo can be used to wash the hair, /T warm or hot wntef is not available, but cold water is. use cold water. Do
not delay decontamination •© obtain warm waJer. Two penoiaslMe alternative sldn decomamhtanB Include the
M29l Skin Decontaminating Kh (SDK) and a 03% sodium bypoehhrnte solution. (NOTE: The use of (he &12?1
Mncture GB«Hcx Page 4 of 10
-------
SDK meter 0 *'» sodrun h)podilcmieen tkin rs appropriate in ututlionv where soap and water ma> noihe «
cftlcadcus in phyticeDy removing paihcuto typei of nave tgetvw wch $\ (host tiled m cei'ain reteaich srtd
devdopaetiilaborshmes Ndfher toap end water, 0 S9««otfiun> hypochlorite or the M201 SDK have been shown
tn be mmt tiftkaootu than the other for pfc)sfc*ny reeaovinn everv tvpe of ocrv* age« Crow the ifclfi.) If used, the
ft Vt toftim hvpochtaute should b« applied wrth mild to moderate friction, wilh a iiaate<«w sponge or w*shcknh
in the fint rod second warites The third wash tbouid be* no* tn remove any residual fodtumbtpocMontewith
copious amount* of warn or hot water
Kye Cootark Jmmcdiateb lean area of contamrrtitfon and begin flushing eyes, mutoas membrane*. or open
tvoonds with sterile sahne or water Flwb the eyes inunrdroidy with sterile talioe or water bv tnbng the head to the
»Mc polling the eyelids apatl wrth gloved finger* lod pouring slowly into the eyes A Morgan lens may also be
for continuous eye irrigation, Although tntciii (pmpomttng of the pupils) ma> be an catty sign ofagem
ecpewie, an injection win not be administered when miosis rs the on)y sign prejent Instead, the individual wtD be
taken Immediately to a medtcal trealment (befliiy for observanti
IngMtlom Do not induce vomiting. First symptiww me Hkdy ^ bt gestreinteitinal hwnediaiHy KdrrJtURer
Nerve Agenl Antidote Kit Muk I. Seek medical attention Immediately. Do not handle vomited material to
•void farther eeatanhaatton.
Idhstattau; If breathmg t$ dtflftcall administer o»V8«l (fbreathlng has sopped, give artificial respiration Sfouth*
to-mouth rttutdtition thoutd be Wed *Her\ ftpptoved mask-bag or oxygen delivery systems arc not available. l>o
not use mouthto-momh tesmdiaiKm when fecial contamination to prtaent 9cch mediud aftetmon Immediately
Nerve fcaergtoey Treatment: Ao individual who bas received a known oerve agent exposure and ba* progresiive
stjtas and symptomi of nerve agent exposure nay receive up to thru sets uf (he Nerve Agent Antidote Kit (Mark I).
Iqcetiortsmsvbe edMiiuuejed at 5 to 20 minute interval*. no more Hum three (A) bisector ris will be given unto*
directed by medical peraeajte) ff revere signs of ageoi orpmttre appear l«gns and symptom* of moderate exposure,
piss generalized weakness or fo gen'
CaS apbysirian.
Ingestion Aspiration baxnd If cwillowvdl DO NOT INDUCE VOMfTING. Nevn gtvv anyfting by mouth id on
uncooicious penon. Oet neAeiA attention nmnediately
SJrfn Contact; Remove contaminated dottring Wipe oflTexceas from siin Wash skin whh soap and water far
ai least \S minutes Oet moftca) KtcntiooVf miuboft developi or peisisu
RyeCootaelt ImmadloteH'Huth «re< vnth plenty of water for of least IS minute*, lifting lower and upper eyelids
ocustamtty Oto medics) ftttenbon immediatety.
Section VI. Reactivity Data
Sf*Wltyt 1he mature has hecn found to be tlabktn sealed co&tomen for up to iSmotrthsolorbelow^C Use
of (He mixta* and atorago above 4" C will hasten (he degradation of the OB within the noxttsc
Reactivity Datsi for GB:
Deeompcyrtfon TernperaUwe; Peeoapow completely at 1S0T witWp 2 V» horns Rite of Hydrolytf * Varies'
withpHftfwltempemufe. AtZQ*C.iu-27nan5JpH 1: ti '4brg 80tu pH tt < * S.4 ndo
@pH lOaoiiis-06min@pH 11
Hydroiyils Prodoetr. Uodet addle eoadWons. hydrogen ftooride (HT) and isoptopyi methylp*>o»phorde acid ,
flMPA) are formed winch farther hrfrulygo to produce aettnlphoiphcirtc acid (MPA) and »»op>opanol Under >
alkalloe conditions, merhytfluorophosphonic odd (MPPA) and tsopropyl alcohol arc formed and Kirher hydrolyee
to produce MP A end HP
Haxartfotrt Polymerizations Ooet tka occur.
Reactivity Oxta far flexaan
Incempadbfllty: Strang OxWcen
BaianSovt t atymertaaDoo*. Wit) not occur
Haxardow Decomposition: Bnrits toxic Aimes of. Carbon Mbeoxlde. Carbon Dimode and acrid smoke
Condi tie oi to avoid: Ignition edtnecs. excess heat and deccricil ipirfc.
Section VII • SpIIL Leak. And Phn
-------
sandoteartht Decontaminate with sodium hydroxide Scooo op all material and pUce in » ftOT approved
container. Caver the content* with sodium hydirvUe Aftct treting. decottJemifule the exterior container end
labeled according to HPA and DOT rcgtftationf All leaking containers will he ova packed with scabem (c.s
mmktdite) placed between the intent* end e*terief containers Decontaminate and label accordfag to EPA and
DOT tegttlatkms Dispcveafdecentemtoateaecordnig to Federal, state, and local tan Conduct genera] area
monitoring to confirm dun the atmosphinc coaceutrMtom do not exceed the AELslSce Sections V and Mil)
Waste Oltpoctti Method; Opeapt bunting or burying of OB or Item* ccrnn'mmg Of toruarainalcd wHb G9 in say
quantity is prohibited. Waste OB and associated decontamiiPboa sotutiona may be Resource ConservotiM and
Recovery Act (RCRA) cegulated hacardous wuus due to a Stitc Itattag of the chemical agent, ot the characteristics
of I he watte, to include contaminates. An evaluation of the Pedernl and Stale wte disposal regulations most be
conducted to determine the epprapuatt dttposd method
Section VIII - Special Protection Information
fhemfomtation provided berets taken ftamtfeaneMG&MSDS As fa highest concentrations oTDiiuteGB this
fatforaiUlnn eppftea in whnle. For !owet concentratloni of Dllotr Oft, the information provided heir are fbr
Uuwlaute and tha specific use of protective clothing end equipment should to based on the mk nsessmem approach
in accordance with good safety and ioduitnal hygiene principles
Exposure Limits for Rcenrrrtgrr Weltttian far CB-
UoprolKlrd Wortoi'
CflossMo^avlmaWi IfimUiWto
Lais than or equal toO.OCOOJ1 8 tours
Up to or fen thin O.OfjOOtf 4hoW
Protected Worker*:
Type of Respirattuy Protection Worn (based on monitoring tesuta).
I. M40 Miliary Mask. CORN NTOSH Approved Full Face Air Puniytflg Respirator
Concentration fmft/m*') JQnfiXhniJf
Not greater than 0 OOIS UpfoShuurs'
Greater tan 0 0015 and leas than 0 002 Up to 6 hairs
Orcater than 0002 end less than 000) Up to 4 hottn
Not greater than 0.005 Up to 13 manias'
2 Pressure Demaod Supplied Air Respirator with Foil Face Respirator
Concentration XuhlLuhU1
o.ooooi to 0 l* Time fimt aill be kept at a minimum to
perfowa (be operation, and wtl be dictated
by die local Heat Stress Program (or
Mixture GB-Hot Page 7 of 10
personal protective eqiripmcnt and clothing
5 Pmwi* Demand Supplied Air Heiptretor with full Face Respirator m combination with an Auxiliary
S*tf-cent*imd BreaJtwng Apparatus (SCBA) or just SCBA
Greater (bin 0 I These concentratum* rhould be expected
only In emergency situations Operations
should not be conducted at these
concentrations.
' As an 8-hr TWA overage
'Maximum continuous Kmc at this concentration RquK-aJcni to *'hr TWA Source Implementation Guidance
Mcy for Rev bed Ahborrte Exposures Limits R* OB, GA. GO. Of. VX.il. I'D, and HT. Deptof Army. Office of
the Assistant Secretary o the Anuy InstslUtroos and Environment, 18 June 2004. See Table 2
1Csnifter for M40 Mask null be changed out every 6 hours of use
'Based oa APFof 50timej the STEL (0 0001 mg/tn'l which is a 15 minute TWA Only 4 excursions to thu
coeoektsatbn with a 60 imtwle intervel between each one ia rilowed durmg an S hwr workda?
'The lenmedfalefy Dangerous to Life and Xealth Vahte
*Foe SCBA wea»n.tiineUtnitie«Antt(««edby life oftteaircytindcMmeximumof3 the fife of the breathing air cylinder; and egress Root the ire* must be performed befote
its expiration
Personal Respiratory Protection far Heiaoet If the exposure limits ere exceeded cad engineering controls are not
feasble use a NIOSH approved respirator.
VentHstfen System:
A system of local amftr genera] exhaust is recommended to keep employee expoiurcs below iKe Airborne Exposure
Units l,ore) exhaust ventilation ttgaaeraUy prcfomd because H can control tht emissions of ihe contaminant ai m
souice. prowling
-------
Other Protective Equipment; For Wk» alary operation! recommend u-Mnag fmpervta.* protective cleihtng
iach*tn|jimrt». tab cnat. apron or ccrvtrailv « apprapmte to prevent »1un wwtact IntheciwofaxpiU
ihe minimum or elective dotNnq should b« donntd «ftet the rik H»« hern evaluated
Mentoring: A> tilftbta monitoring equipment fbr agent CD i> (ho MLM^ ddeetof paper, dcfetiot ticket,
M2S6/MHoAl kitj, bubbler. Depot Area AirMcnhcn&j Sytiem (DAAMS). Automated Continuous Air
Monitoring System (ACAM*). Rcal with special oJtenDoa iiveo to hair. face. neck, and hands
using pfcnt) of soap and water before leaving at the end ofth* woiLday
Olher Precautions: Mixture should be itned in en e*plotjon proof refingerater with a low temperature alarm
Keep tightly dosed. Keep awa) farm heat qmts, and open flame No smoking Take precautionary mtasura
against italic discharges.
For additional information see'AR H5-61. The Army Toxic Chemical Agent Softly Program." "DA Pun 1S5-61.
Toxic Chemical Agent Saffetj Standards.* and "DA Pan 40-8. Occupational Heahh Chndctincs for the Evaluation
•ad Control of Occupational Exposure to Ntn e Agem* OA. UB. OD> end VXM, and DA Implements troa Outdance
Polir) for New Aabeme Exposures Limits (of GB, CM. OD.GF, VX, H, HD. and HT dated 18 June 2004
Section X - Tramportallon Data
Shipping as a Flammable IJqnU:
This mixture b considered a Flammable Liquid for Dilute GB concentrations at or below 0.13 rec oil
Proper Shipping Namei Flammable I tquids. Toxic, n.o.L (Haunt and lsop(«pyt
mcfbytphosphooofluoridatel
L'N ID Kttmbtn UN W2
Dot Ilaaard Ctaiwi 5.6 I, Packing Group I
Del Label: FUnrmahlc UquidTuxic
Del Mirtda^n Flammable Kquldi, Tome. n.o I (Itaunc and Isopxnpyl methylphosphoncrflooridate)
l/NI9*2
Dot Ptsnrrd: Flammable and Pohoo If placard It required
Shipping as a Toak Liquid:
Mixture GB-llex Page 9 of 10
This mixture n considered a Toxic Liquid Tor Dilute GB crmceiitratMM greater than 0 13 mu, ml imJ let* than or
equal to i.0 my ml.
Proper Shipping Fernet Toxto by iohaUfion liquid. flammable, not (Heme and Isoprspyl
otcthytphosphoAofhtortdotc)
Ch ID Number i:N5)M
Dot Haeard Class? 6.1 Packing Group I. Inhalation Hazard Zone B
DOT Label: Poiton Inhalation Ifaxsul or Toxic Inhalation Heurd Sec4*» CFR 171 40Oal*)t)> for
exceptions to umt packaging labeling and 17) 1(b) fbr other exceptions when material is transported by
Technical Rscorl Onlu
NOTE; *"Poiiotr and'Tttut are used mteichtngeably for all raatkitiga, labdt and placards in
continental US transpotianon "Toxk" ii required for International transportation
Dot MarUngt Toxic by tnbalaiion Uquid, fUmmabie, o.o i (Hexane and lsopropyl
mefhjriphosphoflofltraridate) UNUtd. Inhalaiion Hiutd Zone B
DOT Placard: Poison Inhalation Haeard or Toxic Inhalation Hazard
Rmrrgency Acefdeol Prvrsuffoof aad Procedom: See Sections IV. VII end VIII
Precautions To Be Taken In Tfempovhrttaa: Motor vehicle* will be ptaeaidetf per DOD 4WP,9»K Dnvm will
be given full cnfbrmatioa regarding shipment end conditions in case of an camgency. AR $0*6 deals speeneally
with (he irapment of chemical agents.
The Edgewood Chemical BMogkal Center (ECBT). Depertment of flie Amy believes that the data contained
herein are actual and an the remttr of the tests conducted by ECBC experts. The data are not to be taken as a ,
wanafNyerrcpremrtatioo ftw ivfdeh die Department of Ibe Army or ECBC assumes legal f«cponsfl>itH>' The* are
ofTbred solely Car consideration. Any use of this data and information contained in ObsMSDS muat be determined
by the user to be m accordance with eppli cable Federal. State, and locri taws and fjtufatfona. '
Mixture QB-Hex Page 10 of 10
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Mixture Lethal Nerve Agent (GD) InHtxant
Rrvbtd: II Jose2007
Section I - General Information
MMnrfhctom't Address:
US ArmyFdgtwoodChemical BiologkalCenter(ECBO
ATTN. AMSRD-RCB^B-CR
Aberdeen Proving Ground, MD 2IOfO-5424
Busmen Phase: 410-456-4411 or 4414, Mendsy rhfwifb Friday duriaj tfee hour* of 8 o6 AM to 4JO PM EOT
CAS Rtghtry Number*: Nan laown for ftte mixture
CHemteat Ninti Pinicoiyl methyl pbosphoMfhtondate «nd Hchjrc
Trade Nine ud Syeeeyeu:
CIDioteKTnt
CASARMCD
RJDTH Dilute GD
Chemical Pea By: Mixture of a nmiuiatcd aganophosphorus compound and flammable solvent
Muterctar Format* GD: C»l!i»POiP
Mderstar Formal* Hetaoe: CHh
NFPA 704 Signs >r
NmIiS (
nir* <*>»*>'•»>
Sptdll-O
Section » - Ingredient!
Ingredlents/Nute: ODftHrxane
CoBctotrattoBt Dilute OD sohthms vaiy ia ooaceauatioa from 2.0 mg of GD pes mUtltitcr of Hfttfit to 0.012 us
ofGD per milliliter of Kcxa&i
Section m ¦ Plmlcal Data
AppearureoadOdoroTGDi Wfwn pwe, cokfftess liquid with a fruity odor With impurities, amber or dark
brown with oil of ¦camphor odor.
Q.dcM, (I
cn\iu W
NOTE: Due to low eonetrttradocta of tgtfu fa Dilwr GD die remaining phytic*! propefttel given sn those of the
Homo, foraddmoju] GO properties tefei tofhcDcvtOD MSDS. 1
Appetrtocctftd Orion Cotortcss liqad with a mild solvent type odor.
Boflioi Poiat 7« mm Hg: 60* C
Vapor Prtsstsrs (mm fit)*. 1S)<&2S*C
Vapor Density (Ah—1): 2.97
Specific Gravity (HtO-l)] 0.66
Vteeotftr. 0H mP»!$2 and aleohoHesistaip foam Witer maybe ;
ineflfcettve Avoid use of eKfingoisfctagoelhoib that will cause splashing or spreading of solvent
Special Fire Figblbtg Procednrcs: All person? not engteti m eJrtinguiifiiog the fire ibcuM be Immediately
evacuated focataua Fires ihould be contained to prevent spreading to luxoptfollcd m Whenreiponfirta to
a fin atom to bulldlngl or areas contenting tohrems,ftr»41gfitingpfrvoanelifcoQ!dwBirftrfI firefighter protective]
doQgog (flame tesiitanl) during fire fighting and Pre rescue operations Respiratory protsewoa h required. Positive
pttttsm. (\UUoce piece* HIOSH-epproved tdfcddcnttflci4efli(CAI)opef«tiOM
officer. L'se water spray to cool fire-exposed containers
NOTE: Do not breathe Aimes Skin contact with nerve agents mini be jvoided at ell does Although the fi« may
destroy most of the agent, care must sHD be taken to uton the stent or con timing ted liquids do run farther
coraaratnett other areas or sewers, Cootact urtihUquidGD or vapors eta be (eltl.
C'maoel Are and Eipkiikm Huinbi Vapor msy travel considerable dltsac* to tource of igmtioA and flash back
Cootamer cMploston may occur under file coodniofts Hnerial Is Rtfitertliafl wicer end may bo spread by the use of
water
Mixture GD-Hex Page 2 of 10
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Section V . Health Harard Data
Airborne Rtposure Limits (A£L):
For CD1)
Worker Population Limit
: (WPU)*-tv TWA 1
nurtn'
STTvl. l5-«mTWA'
mgftn*
idlh;
mg/m*
General Population lbntt
(GPL) 12-hr TWA 1
m«"m5
I 000003
0.00005
00$
0.000001
' Thexe values em be found in the DA, Office of die Ass»tant Secretary. Installations and nm-tronmeiu memo,
*ufcjeci Implementation Guidance Policy for New Aiibome Exposures limits for GB. OA, GO. GF. VX. H. HD.
andHT. J8hine20O4
1 To data. The Occupations) Safety and Health Administration (OSHA) have ool promulgated a permissible exposure
concentration for CD,
1 TWs value ran be found in the OA, Office of the SurgtOn (Jeneial memo, Subject Nerve Agent Pcnidancoas
Exposure Cmena and Airborne Hxpowre Uvd» (ABL») Tor GD*GF for dm in Interim DA Outdance on
ftnpjemcntarion of the new AKLa, 2*> June 3004
For Resanc:
Threshold limit Valoe (TLV): Tbc TLV fee hcxanc is 50 ppto or 110 rag/m4as an eight-hour time-weighted
range (TWA)
PQj 5C0 ppm or I tOO mgM\' TWA.
This nwiture is «rt listed Vy the International Agency fot Research on Cancer (IARC\ American Conference or
Governmental Industrial Hrgiottsa (ACfiUU Occupational Safety and Health Administration (OSHAj, or Nations)
Toaocotofy Program (NTP) as a cardrmgeft
Tlte mixture tfcouW be treated as a poisooous and flammable liquid Personnel should avoid contact with the
admire and ose appropriate typcslevels of protective doihing and equipment
NOTE: Them is presently no toxicity data Bar the mixture of GD and Hexase. Tha information provided here is
taken from the neat GD MSDS.
Roettrs of Entry? The primary rtnites of e*pu»we to GD are inhalation and ocular expowrcofvapor and liquid
contact witfi skfo A secondary and leva HMynmta of erttj can be through ingestion.
Effects of Exposure: Have exeats ace readily absorbed and are hstardcnss through all routes of exposure The
most prominent physiological effects result fiom the Inhibition «f ChB in the ceniul nervous tystrm Tbc result
products effects imluding miosis, rhmorrhca.broncboceaitricttoii, increased glitroratestinal motility, muscle
fesciculatiom, wejJuiess. flaccid paralysis, difficulty in concentrating, anxiety, ittsnmma. r«sftei«e*t. deptmkin of
Ihc respiratory center, convulsions and death
Signs aod Symptoms: The onsrtofthc signs and symptoms foUofting exposure to nerve agmts may occut within
seconds, minutes. or hour?, depending upon concentration, dosage, and route of entry, as well ai the type and
physical state of tbc nerra agent
(M) poses both a vapnr and liquid hazard to the unprotected worker. The first noticeable eflfeas from vapor are
miosis, tight chest and/or rhhionhea^ These rigos can occur In the absence of measurable ChC inhibition in Ihe
Mood Late, msld signs and ayiaptoms of vapor wyown include conjunctival injection. pain behind the eyes.
Mixture OD-l!cx Page 3 of 10
dimncn or blurred vision and excessive sahvatron
Mode* at* signs and symptom of *«pm capcaurc may mdudr mild signs and symptoms of exposure plus: increased
shortness of breath, coughing wheezing, votemfrtom broncbonbea, nausea, vomiting aod diarrhea
Severe ngM tad symptoms of vapor exposal* may include moderate signs and symptoms of exposure plot,
generalised weakness or facicuiationa'twttcfiing. loss ofcotKcionsness (within seconds), convulsions (within
minutes), severe respiratory £ stress, (laectd paralysis and apnea
Effects frem'liquid percutaneous exposures to ntx agents aro slower to develop and slower to reach their pesk
when compared to vapor exposures of the eyes or respiratory tract Mild Ngns and symptoms cfHquidoerve agent
dun exposure Indude localised sweating *1 ihe site of exposure aod fine musde fjuaculatens/twitchrng. (NOTE:
Miosis is not an early sign of Kqtdd skin exposure This is only Que for exposures dm inctuds contact with airborne
vapor with the eyes In eases of ntrve agent exposure not tnvtfvtng vopor contact tyHh fheeyes. taxmsmay be on*
of The tut effects to occur In juchtaae*, the dosages of liquid exposure which produces miam arc notsigmficenily
AfTbent than lethal doses )
Toiktt> Vahm:
V«Ber nrhtUlten/Onit.r)1
ECISO (Mlldl - # 4 mp-mln/m "
ECt5t» (Severe)1 * 25 ng-mia/in*
LCt50 "¦ >5 mg-jnin/m1
V«°°r
-------
Liquid Skin Exposure: Love aiea nf contamination n 1 Skm DeconttnlsiimgKft (SDK) and tO S% swfiuro hypochlorite solution. (NOTfci The use of the M2?1
SDK and'or 0 5% sodhim bypodrtonte on sfcJa it appropriate in sHusdom where sotp and water may not be as
efflcsetotn in physic*fly removing particular types eif nerve agenta. toch at those mo) in cmim research and
development tafeotetsnest Xtstitas soap and water, 0 5* '• sodium hypochlorite or lira M29 i SDK have been ihown to
be more dTlcadouf titan the other forphyaiedly removmg every type oTncive agent from the skin) (fused, the
0 <% sodium hypochlorite should be applied with miU to moderate JHctran. with a sift|te-uie tposge or washdoih
•,n dj« first and second waihti The tMid wish should be antue to remove any residual sodium hypochlorite witfi
copious erooacts of vrtnn or hot water
Eye Contact; tnmedhtefr leave net of contamination ami begin flushing eyes, mo com membranes, ot open
wounds with uento saline or water Fhnh the eyes immediately with sterile saline or water by hiring the head to the
side, pofltng (be cychds apan with gloved fingers and poortfifi slowly into the eyes A Morgan lens mav aho be
uacd for continuous eye tmgitioo Although rruouj tpmpoiitwog of flw pupil*) may be ed when approved mask-ban or oxygen delivery systeou are not avdlatfc Do
nor tne mouth-tofuouth resusdution wheo fecial contamination a present Seek medical attention Immediately
Nerve Imirfinty Tr—teaentt An tetfttduri who has received n known nssre agent exposm end has pre^resihre
signs and symptoms of nerve agent exposure may receive up to three sets of (he Nerve Ajteit Antidote KH (Mart l>
Injections m*y be admintaemf at 5 to 20 ratauto ietervala; no more than three (It injectoi sets will be given unieu
Arectedby me&cd penotmd. IT severe sfges of nerve agent exposure appear jsHp» and fymptomi of modcrat*
exposure, plusgeneralued weakness or AscieutatmVtwitcWng. Iossofcwmkwsueut Central oervous sysms, eyes, skin, respiratory system, and periplmal nervous system
EfSeets of Eeposnre:
tntahtlsn: labatattoo of ytpoet Irritatee the reipaatory tract Ovmnnusur* may came Ugteheadedneu, nausea,
headaohe, and btuired vision Greater expoavre may caasc musde weelmess, numbceai of the extremrties,
tmeonsdoweness and deadi,
tegeeileei May produce abdominal petn. tttuca Aipirirtofl into hjngs can pfoduce severe lung damage and is a
meficaJ emergency. Other lymptotm expected to parallel inhalation
Skin Contact? May cause redness, irritation, wttb drynen, cnekliig.
Mixture OD-Hex Page 5 of 10
Kye Contact: Vapotsmay cause itntation Splashrsmay cttfte redness and pain.
Chronic Exposure: Repeated or prolonged skin eoctad may defal the skin and produce irritation and dermatitis'
Chronic inhalation may cause pcjlpheral nene disordera and central ntr\m« »y«tcm effects
Aggravation of Prr-exbttng Conditions: Persona wiih pre^dsdng Are disorders or.eyc preblenu or impaired ¦
respiramiy toctten nay be more susceptibte to the effects of the substance, May affect (he developing fetes
Cmargeoey and First AW Procedures:
Inhalation: lUmove lo fresh air. If not breattring, give artificial respiration Ifbreediing is dlfTtctrfi, jpvo oxygen
Call a physician
Ingestfam: Aspiration hazard if swallowed. DO NOT INDUCE VOMITING- Never give aoythmg by moulb to an
unconscious person Get medical attention taunedtately
SUn Contact: Remove any contaml&ated dotting. Wipe ofTexcess Dom ikio Ws
-------
Slept . the information provided here aie for
pndance and iht specific use of protective dothtag and equipment should be toed on the risk assessment approach
in accordance with good safety and Industrial liygtene principles
ElPOiart 1 Jroftt for Renrtrtorv f rolrrtten for CD:
Unprotected Wortos
C«ncenfi*fiCT.(!nB&D) E*W_l,aft««
Less Qiao or equal toO.OOOOJ' Shnurt
Up to or ten than 0.00012 2 boors9
Protected Worfcen:
Type of Respiratory Protection Worn (based on monitoring remits^
1 M40 Military M&sL, CBRN NtOSH Approved Full Face Air Purifying Reapiratof
OjKMWisfUro'n/l TimtLimlH
Not greater than 00015 Up to 8 hours'
Greater ibaft 04)915 and less than 0002 Up to <1 hours
Greater than 0.002 end leu than 0 0025 Up to 4 hours
Not greater than 00025 Up to 15 minutes*
2. Pressure Demand Supplied Air Respirator with Pull Fact Roptrator
Mixture GD-Hsx Page 7 of 10
CflntaatatisaXmstini
Time Limits*
0 0000310005' Timo limit will be kept at a mlntmujn to
perform the operation, and will be dictated
by the local Heat Stress Program fw "
personal protective equipment and clothingl
3. Prejwre Depend Supplied Air Respirator with Full Face Respirator In combination with 40 Auxibary
Srif-comaitttd Breathing Appusxu) tSCBA) or jusi SCBA
Concajttitipn (tng'fn'j Time Limit^
Greater than 0.05 rhese eoncentiations should be expected
only in emergency situations. Operations
shooed not be conducted at these
ooneciiuatkMU
1 A« a* S-hrTWA cntragc,
' Maximum cotrtjmtflus time stilus coftctAtrtnea BquivalenttoS-hrTWA. Source Implementation Gtudanco I
Policy f« Revised AMorac Exposures Umits for OB, OA, GD, GF. VX. H.HD, and HT. Dcptof Army. Office «f
the Atttstaei Sccsctasy o the Army fnstsUationt and Environment, \g hme Z0O4. See Table )
'Canister for M40Masl most be changed ost every 6 hours of use
4 Based on APF of SO trves the STEL (0.00005 mgfnfy. which u a 15 araote TWA Only 4 mwpons to ttns
conccAtmion with s 60 oitauta interval befweeo each one It allewed during on S hour workday.
'The hnmeifiatety Dangerons to life and Health Vjfae.
fc For SCBA wearers, time lint is contained hy Hft of the olr cyDader (manmom of 30 to 45 minutes) For Air
Supply wwers. time limits should be kept to a minimum. Should uee of the amifiary SCBA be oec entry, time
linir will be coostmoed by the life of the brealhmg air cylinder, end egress from the area most be performed before
it* eaptratlon
Pennant Rftptmmry rraierUeit Tor HoMt; Iflhe e«poiur«lirtit» are weeded and engineering controls are not
feasible use a NIOSII approved respirator.
VeodtatloB System]
A system of local •nd'or general exhaust is recommended 10 keep employee exposures below the Aubonte Bvposore
Units. Local exhaust ventilation >1 generatl}' preferred becaun H can connol (be «mt»rions of the contaminant a! its
source, preventing dtspenwo of n otto the gentrol vmk arcs.
Specials Chemical labaafoty hoods will havceji average Inwaid fcccvdodty of 100 linear fixt per udmitc (ll)»n)
Ji;- 7t^% w^hthevelud1y li *n> pohrt not deviating fVom the avtrage bee veloci^'by more than 20%>, Ending j
laboratory boodi will have snwwud ftct velocity of ISO ll>m »¦/- Laboratory hoods will be located such that
crois-(fratodofi0texcced20%oflHc inward face velocity A visual performance test using tmofce-produring
devices wltt be performed in assessing the ability offlw hood to contain ogent
Other Reorcutaaoo or exhaust air ftan chemleal areas KproWWied No connection between chcnaca! areas end
other areas duough ventlUoon system It pennicted Emergency backop power is neceasarr Hoods should be tested
•i Ibmt seTTOttmuany or sftrroiodrficatroa or maiatejtance operations Operations ihsuld be performed 20
centimeters inside hood lace
Protective Qova fer Neat CD: Butyl Rubber Gtore M) and M4
Mixture GD-Hex Page 8 of 10
-------
Nrrtoir. Chemical Protective dove Set
Dewntarmnatc and change butvl nibhet glnvei hi rhe even! of contact with liquid Kexane nnce Hexene degrade*
butyl rubber
Eye Protcttfont At » mmftnum tsfey glasses witfi side ahtddi wilt be wont For splash hazards use gogg)e* and
face shield Nfaintain eyewash facilities m »o»k ma
Other Pr«ttttiv» Equipoirnt: For lefroratocy apenttkrtu. KCtfwmend wearing ini pen tout proactive dotfuwg
including baou. glove*. lab coat. *jTnm or coveralls, at appropriate, to puvvm skm contto. to the com of a tpll.
the mid mum protective dotting should be domed after the irto h» been evaluated
Monitoring: Available oumhmng equipment for agent GD ti the MfcAf drteclor paper. detector ticket.
M2S6/M356A1 kits, buhbler, Depot Area Air Monitoring Syattm (DAAAfSl. Automated Continuous AH
Monitoring System (AC AMS), Real'Ttme Mouto (RTM). Dcmihuriutraa Chemical Agent Concentrator
(DC AO. M8.VH3, M6AI/M43AI. CAM-MI. Hydrogen Flame Photometnt Ems in on Deiectca fHYFttDX (ho
Miniature Chemical Agent Monitor (MIN1C AM), and du Real Time As at) lieal Platform (RTAP).
Section IX - Special Precaution
Precaution* To Be Tafceo In HaodlUg and Sterttif: When handling mixture the buddy system should be
incorporated No smoking, eating. or drinking w mas crwrtnlmng tgenta'aohenta ii permlncd Containers should
be periodically inspected for leaks Strmgent omtroJ over alt pcrtomd'pnclices tmatboerertiicd
Decunttaitnatwg equipment will be conveniently located tfedu must be designed to perron rapid evacuation
Chemical sbovrer*, eyewash stations, personal deanttMis fhaGtiea. and An oaingashera mm be provided Wash
hands before meals and. as appropriate shmw thoroughly wtth special anernlm given to Halt. face. reck, and hands
using ple&tv of soap end waler before having el the end of the workday.
Other Pretaulleos: Mixture should he stored to an explosion proof reft tgerator wfth • tow temperature alarm
Keep tightly dosed Keep a%ay ftum beat spark*. and open fame No smoking Take precautionary measures
against tube discharges.
For additional information see "AR1IS4I. The Army Toxic Chemical Agent Safety Ptogram." DA Pam JM4I
Taut Chemical Agent Safe*} Standards," and "DA Pam 40-S, Occupational Health Cwdchnes far the (haluaflna
and Control of Occupational Exposure to Neme Agent* OA, Gft. GO. end VX", and DA Implementation Ud dance
Policy lor New Anbome Exposures Limits for OB. OA, CO, GF, VX. H, HD, and HT dated II June 2004
Section X - Transportation Data
Shipplfift as ft VUmmablt Liquid:
This mixture is considered ft Flammable Liquid for Dilute GD concentrations «l or below 0 14 mgfari.
Proper Skipping Nawe: Rammable Liquids. Toxk, n oj. (Hexana and Pinctelyl methyl
phosphonofluortdafe)
UN ID Number: UN1992
Dot tfssard Classj ?, o.l. Packing Group I
Dot Label: Flammable UqoMTmlc
Mixture GD-Hex Page 9 of 10
Dot Marking: Flammable U^iids. Toxk, n.o.i. (Hex&ae and Pinxolyl mtlhyt phosphonnflttoridatel
II^IW
Dot Placard: FlamouM# aod Pdsoo if placard rs required
Shipping as a Toatr Liquid:
TWs mixture ii couidered a Toxic Liquid fot Dilute GD concentrations greater than u 5 4 mg'ml and lest than or
equal to 2.0 mgfaO.
Proper Shipping Nam*: Toxic by inhalation liqutd, flammable, n o s. (Hcitsnc and Ptoicctyl meih>1
phospbonoflcoridate)
UN ID Nbrnbrrj 1/N3184
Dot Hattrd Clan: o.l, ], Patkiog (fioup I. latnlillon Huard Zom B
DOT UM: Prason Inhalanon Hatard or Tone Inhalation Hazard Sec 49 CFR l?2.400a(a)(^) for
exception* to umt padagiOR labefing and 173 7(b) (br other exceptions when material is transported b\
Technical Eaccn Uoits.
NOTR; ''Poison' and "Tuxic" ate used Interchangeably (by all markinga. labels and ptacanb in
contloental US transportation 'Toxic" is required for intexnstJMiaJ transportation
Dot Martdog; Toxic by inbatallon liquid, flammable, n.oa, (Hcxane and Pinacolyl methyl
phosphoAoOuo>Htate)!r\33§< FnfcsUtton Hazard Zone B
DOT Ptetnrd: Pobon Inhaiaueo Haard ot Toxus Inhalation Hazard
Eairrgenry AerhSectl Prrarallotu mid Procedum: See Sectiofti IV. VII and VIII
FrecaotloB* To Be Taken Is Transportation? Motor vehicles will be placarded per DOD 4500 94L Dnvers will
be pven (ViU tsfbrmaxiod regarding shipment and corufitions in case of an emergency AR JO-6 deals speeffiedfy
with the shipment of chemical agents
The Edgewood Chemical Biological Center (ECBC), Department of the Army believes that the data contained
herein are ictus! and are the result* of the testa conducted by PCBC cApaii Tlte data are not to be taken as a
gursggy ot reprttantttloft far which the Deponmcnt of tfie Army or ECBC assumes legal itspowiihillty Uteyare
oflered aoldy fat ctwtiideration. Any ust of Has data utd mformaUon cunuiacd m this MSDS muat be determined
by dw u»er to be to accordance with applicable Federal. State, and local law and mpilatlow.
Mixture Q D-Hcx Page 10 of 10
-------
IMmii
LcthalNerveAgent (GF) In Hexanc .
Revfet* II iunc200T
Section 1 - General Information
Maaobttartr's Addmr
U S Amy Edgowood Chemieil Biological Center (ECBC)
ATTN: AhfSRDECB-CB-CR
Aberdeen Proving Oramd. MD 21010-5424
Business Phone 4KMJM4U or+414,Monday timsughFriday dunagtbe hooncf 5.00 AMto4 ttPMEDT
CAS Registry Notnbtrst Neat Vnown for the mixture
Chemical Name: fydoh*^4 methytphospbonofhnmdateandHtxanc.
Trade Name end Syoenymax
OF in sahent
CAS ARM OF
RDTEDflnte GF
Chemical Family t Mixture of a ftuorinated orpiftophotpSonn compound and (lamwrtle solvent
MolmdarFonmrtaGF: CtHMPFOt
Molecular Feraaia Htuac: QH,,
NFPA 704 Sgnali
>h*W« 4
j
Specral*0
V-
Sccllon II - Ineredienti
httm$irnts/N*m«: GFftKtium
Gomcotratloo: Dfhm Of lohtfloas vary fa conutmadon from 2 0 nig of GF per mtlllBter of Hexe»eto0012 tig
of OP per ailfifiter ofHexane.
Section 111 - Physical Data
Appearance and Odor of GFs Colorless liquid, no odor if pure.
cn \ll* W
NOTE: Due to low coaccntntiani of agent in Dilute GF (he remaining physical properties given ere ihote of the
Hexane. for additional
-------
Section V - Health Hamrd Date
Airborne Exposure l.tmitt (AEL):
ForGF5:
Worker Population Limit ;
(WPLlS-hrTWA1
ntgiln
STEL 15-minTWA >
mg^m" I
1DLH'
mg^m*
General Pupulation Lnrnt
(OPLl 12.br TWA1
0.0030J
000003 1
o.os
AJOOOOOI
' These values can be found ih the DA. Office of the Assistant Secretary. Installations and Emtroamem memw,
subjecr Implementation Guidance Policy for New Airborne Exposures Lrnihi forGB. OA. 00. iiP. VX. H. 110.
artdHT. II June 2004
1 Tu date, the Occupational Safety end Health Adntusiution (OS! IA) hive not promulgated 4 permissible exposure
conceattaUoa for OK
* This v»l« en be found in the DA. Office of the Sttrjtcon General memo, tobjttt: Nerve Agent Percutaneous
Exposure Cittern end Airborne Exposure Levels (AfiLi) for GDftiP far use in Intenm DA Guidance un
Implementation of the new AELs, 2® June 2004.
Per lleiMe'
Threshold Umtt Value (TLV); The fLV forhcxime is SO ppm or ItOmgrra'as an eigbi-hixir time«wrtghtcd
iwige(TWA)
PEU 560ppmorl&00fng»W TWA
TWs mixture is not tiffed by (he totematiorMl Agency for Research on Cancer (tARC), Americtn Conference of
Onvetnmeniel Industrial Hyitenlsti (ACGIH). Occupational Safery end Health Admlaistraaea (OSI1A), w Nation*;
Toxicology Program (NTP) as a carcinogen
The mixtum iboutd be treated as a poisonous end flammable liquid. Personnel should avoid contact with the
mixture and use appropriate typexleveb of protective dothing •nd equipment.
MOTS: fhere is presently no toxicity data for the mixture ofGF end llexonc The infbrmitkm provided here Ii
taken from the neat CP MS0S
'Routes of Entry: The primary routes of exposure for Of ere wbaUtwn and ocular expmoic of vspot and Itquid
contest with A wwmdery end less ftfctfy rootc of entry on be through Inysrtoa
Effettsof Exposure? Nerve agents ere readily afesocbed end an hazardous through til toute* of enpOMire The
most prominent physiological effects result from the intribidoa of ChF in the centre! nervous tytem The result
produces effects inchsttiag rniom, rbiamfhea. biomhoccnstnctKai, increased gastrointestinal motility, muscle
ftsucuUtfcms, weakBen. neeewt paraJyns. cfifProlly in concentrating. anxiety, insomnia, restlessness, depression of
the respiratory center, cotrndsioos and death
Signs and Symptoms: Ibe onset ofthc signs sod symptom* fotloaing exposure to aeive agents nay occur whhin
seconds, minutes, or bouts, dependng upon concentration, dosage, tod raota of entry, es well ts the type and
physical state of the nerve agent
OP poses both e vapor and Dqtnd hazard to Ibe unprotected wrricer The first noticeable effects from vapor are
miosis, ttgfe chcsl end/or iluamihta These signs can occur in the absence of measurable ChC inhibition In the
Mood. Later, mild sigM and symptom* of vapos txpoaufelnetutecMyuneisval iigecfan, pam bchbtd the eyes.
Mixture GF-Hcx Page 3 of 10
dimness or blurred vision and exeetove solvation
Moderate signs and symptoms of vapor exposure may 'Relink mild ngn* end symptoms of exposure plus increased
shortness of breath, coughing, wheeang, voluminous brumimrrheo. neutca. vomiting and diarrhea
Severe signs end symptoms of vapor exposure may include moderate signs and symptoms of exposure phis:
generalised weakness or fhsriculelionitwitchrog. loss of consciousness (Within eecoodsX cwivnlswtt (within
minute*), severe respiratory distress, flaccid paralysis and apnea.
Effects from liquid percutaneous exposures to nerve agents ate slower to develop and flower to read) their peak
when compered to vapor ocpowrwof the eyes or respiratory tr»cl Mild signa and symptoms effiquid nerve agent j
skin exposure radudo localised sweating it the site of exposure end fine muscle Cocicctitions/twttch'tng. (NOTE:
Mhnis is not ec early sign of Rquid skfa exposure This is only true for exposures thai include coertact whh ahfccme
vapor with the eyes. In eases of nerve agent exposure not involving vapor contact with the eyes, miosis may be one
of the last effects to occur. Is such cases, the dosages of liquid exposure tttidt produces miosis are not significantly
different (haa trthaJ doses )
Modcxate signs and symptoms include nausea, vomiting, diarrhea, headache, and feeling of general neakness.
Severe eigns and symptoms include generaliced fasctculetion* and twitching, respiratory secretions,
imcofiiaousaess. convulsions, flacvid nsusde paralysis, apnea and respiratory failure.
TeslcHy Values)
V«mr n»h»l«a«nK>ralitV1
ECt50 ^fild) ¦ 0.4 mg*nni^m
ECUO (Severe); ¦ 25
LO50 - 35 mg-minW
Vnwr gmmmi wnil"
fcCOO ("rtmltoid) ¦ - 300 mg-^nmrm
P.CrtO (Severe)* - 2000 mgpmin.W
LCtJO « 3W0 rng'tnin/m*
LtonldrPrrertanwnwl
RD50 • 200 mgTO kg man
UttO * J50 mg/70 Kg man
1 Estimases for inhalatton vapor eayesuie ere based en a wtonte vohsme (MV) of IS Biers and a 1 minrte expoaure.
The effective dosages will Increase with lower MV and decrease for e higher MV. The concentration-tune profile is
described by Ate toxic load nedd (CVt) The toxic load exponent (n) is 1.25 The don^eipoase carve is very
steep.
2 Severe effects may also include desth
1 Personnel are masked
* Values for percutaneous vapor am for moderate temperatures (15 "F and below). The effective do sagas for hot
temperatures (E5 T and above) vnH be less by as least a (boor of 1
' Threshold refers lo a slight ChE inhibit!oa
fcmergettfy and First AW Procedures for Mixture:
NOTE: When seeking medical attention, inform medical pcisutwU that (his is a fluorinated organopborphoruj
mixture.
Emerfetity and First Aid Procedures for CP:
Mixture OF-Hex Page 4 of 10
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VepaT Expottirt: Immediately leave ares of coettmiotoca Vapor exposed nerve agent rmialbes should be
decontaminated by removing sfl clothing in t elean alf environment and shampooing or rrasnig the Hair 10 prevent
vapor aftgaoins
UguW Skin Exposure: Leave area ofcontamimrttoo a qukkly ss possible Remove clothing ma dean air
environment tad wash the tltfn surfbee and hair m or hot waicr as least three times. 1 he npid phyriraf
removal of a ehemkaJ agent tt essential. Stubbing of exposed Ucrn with a stiff hush or brisket ii discouraged,
becaoce drin damage mav occur tod ituv increase tbwrption of agent Use liquid soap ^dispose of ©entmnej after
ose and replace), copious amounts of water, and mild to moderate fiictkm witfi astngle-u** ipcng* «r washcloth in
the flat and second washes Tse third wish should be a rime with copious amounts of warm or hot water
Shampoo can be used 1* wash the hair tr warm or hot water it nnt available, but told watt* is, use coM water Do
not delay decontamination to obtain warm water Two permissible altemativa atan daoontamhmta include tha
H29I Skm Decontaminating KiuSDK) and a O.ft* sodium hypochlorite solution (NOTE: The use of the M291
SDK andtorO SS wdiom hypochlorite on ddn is appropriate Id situations wbeie soap and water may rtolbcaj
efficacious in physic«0v removing particular types ofnetvcagifiu asA n those tmd i» cemin research «b4
development laboratories Neither soap ami water, 0 S^w sodwm hypochlorite or the M2° I SDK have beta thown to
be more eflicaciuui (haa Ae other lor physically reoovtag every type of nerve agent from the stun) If used, (be
C.Vt sodium hypochlorite should be applied with mild to moderate frtctioa. mlh a aang)r-use sponge or wariwtoth
in die first and *cond waAes The third should be a nnse to remove snjr residual sadhm hypochlorite with
copious amnunis of warm or hot water
Eye Contact: Imow<8at«ty tetve area of cootunteatfon tad begin fVnbins.e**v reveria membrane*. or open
wounds with exerfta uline or water Rush the eyes immediately with sterile saline or water by tihhty the bead to the
side, pulling the eyelids apart with gloved Angers and pouring slow I) Into the eyes A Morytn lens may also be
ueed Tor cantawot* eye irrigation Alfooogb mfoaii (pinpointing afthcpupHs) may bean cert) ngn of agent
exposure, en injection will sot be edotttusfered when miosis is the only itgn present. Instead, the individual witl be
taken Immediately to a medical treatment fhcallfty for observation
Itqtntftra: Do not induce vemitiftg. Ftwt symptoms art tUaly to bt gastrointestinal tomedlaiaty administer
Nerve Agent Anbdota Kit, Marl L Seek medical attention Immediately. Do not handle vomited malerUlo
artdd further eonlamlnaiion.
Inhalation: 1f breathing is dfflkuft. adnrinhte*-oxygen. Ifbreatfetng has stopped, give artificial respiration. Mouth-
to-mouth re wsa taboo should be used when approved fa*sk»bag or oiygen delivery tyttems are not available Do
not use fnoutb-ro-momh resusdulioo when facial loniawlnattan it present Seek medical attention Imsuedtately.
Nerve Emergency Treatment: An individual «4to has received a known nerve agent exposure and has progressive
signs and tymptoou of neive agent exposure may receive op to three sets of the Nerve Agent Antidote Kit (Mark I)
Injections may be administered at S to 20 minute tntenrala, no mora (ban three ())iq}ector «dj will be given unlets
directed by medical personnel IT severe signs of ncrvt agent exposure appear [ttgns and symptoms of moderate
exposure, plus generalised weakness as hsdodatknft*itching, lots of consciousness (wiMn seconds). coovuJtk-ns
(withia ainufesX sever* resplsatoiy Asbtn. flaood paralyeu and epnen}, immediately admiiastes. In mpid
•accession, all three sets oftfceMttk I te addition, a seeordwll be nwnhrotd of all tegeettcosjven
Beakh Baurd Data for Ueuste:
Target orgn(s)i Central i*ei»ous system, eyes. skm. respiratory system, and peripheral nervous system
BXTVet* of Expos ore;
Iotmlatfen: Inhalation of vapors irritates the respiratory (/act Overexposure may causa lightheadedness, nausea,
headache, and btuned vision. Greater expnsttre may cause muscU «*eaknesa, numbness of the extrennties,
Mixture GF-I lex Page 5 of 10
unconsciousness and death
Ingestion: May produce abdominal path, nauseo Aspiration Into tangs can produce severe lung damage ar^ is a
•nedtcaJ emergency Other symptoms expected to parade] inhalation
Skin Contact: May cause redness, inititran, with dryness, cracking
Rye Contact! Vapors may cause imtatkm. Splashes may cause redness and pain
Chrante Ecpesope: Repeated or prolonged akin contact may defat the skin and prodoce Irmation and dennatlus
Chronic inhatatian may cause penpbcril nerve disordtis and cenoal nm-oui system effects
Aggravation of Fre-t&btlag CondlHanc femww with pro-existing *kin dborders or cy« problems or Imp aired
respiratory ftmdion may be more sosetpbble to the effects of the substance. May affect (he developing fetus
Enttrgeoty aed Fbil Aid Piocedores!
Inhalation: Rcmwo to frwh «r If not bfeafhing. glv« ettiflaal reapiralitm If btcalhtng rs difficult, give oxygen
Call a physician.
lagettfen: Aspiration hax«(d If rwtltevred, DO NOT LNDlX't VOMrTING Never ghe anything by (ooutb to an
uncoriKious person. Get medtcd attention immediately.
SkinContach lUmm-e any contamlnattd eMhhi^. Wipe oft aceas from din Wash skin widiaonp and water for
«l least 15 minutes Get medical attention if irritation develops or persists
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutea, lifting lower and upper eyelids'
occasionally Get mafical attention immediately.
SwttQB VI - Re«ttivm Data
ShUIly: The unxlure has been famd to beatable in sealed containers for opto 12 months at or below 4" C Vse
of the mixture and rouge above 4* € will hasten tiro dcgmdaiton of ihe GP vrilhin the mixture.
Rmctnrtty Data for GFi
Drtompoeitton TMnperaturet Completely decomposes wHhlD 2 hr$ I50T.
Rate af Hydrolysis: ha M 42 h*@25T in distilled water
Hydrolysis Products: Hydrogen fluoride tHF) and cyelohexyl methylpho^honlc acid
Oaaanftws PolyumUaBoot Data not available.
Retdhrfty Data for Beaame:
InfonptabOlty} Strong OxHlxets
flnurtfods Polymerbatln: Will not occur
lUttardotts DeeompesHioni Bmits twk Annas ol Carbon Monoxide. Caiboo Dioxide and acrid smoko
Conditions to avoid: Ignition sources, excess hast and electrical spark
Mixture OF-Hex Page 6 of 10
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Section VII - Spill. Leak. And DI«no»al Procedure*
Steps to be Tklnn hi Cut Material ts Kdttttd or Sptiltd: Gvtcmte tnt. Ww epproprieto pnddgn
equipment as specified in section (See Section VUI) Keep unprotected and unnecessary penonnt! from entering
ares. Sae sWod V for emergency and first aid instructions
Shut off alt sources of ignition Ventilate nmoflesk or spill. Use teen msterial tn absorb jpitl (e.g vcnmailife,
send or earth). Decontaminate crbh eadium hydroxide Scoop up til material end place in s DOT approved
container, Ccvoj the cootrnU with acdhrm h)dro«rde After seating, decontaminate the exterior contarner ittd
labeled according to CPA and DOT regulations All leatang miliums will be over packed will sofbent (e r.
vciininrfiie) placed between tftt Interior end exterior container*. Dccomatnmate and label according to EPA and
DOT tegtdatiotn. Dispose of rtrrontamlnnto according id federal, rate, and local tews Coadoct genera) veo
monitoring to confirm thai the atmospheric concentrations do not exceed the ABLs fSea Sections V and VIII)
Waste Disposal Method: Open pil bunting or buying of OF or items containing or contaminated with OF In any
quantity la prohibited Waste CP and associated decontamination aoiotions msv he Resource Conservation and
Recovery Ad (RCRA) related hazardous wastes due to a State listing of the chemical agem, or (ha characteristics
of tlie watle. to mdodr contaminates An evaluation of the Federal and Stale waste (fopotal icgtriationi must be
conducted to determine the appropriate disposal method
Section VIII - Special Protection Information
Iteinfonratan provided feet* is taken from the neat CP MSDS. A) die highest concentration* of Dilate OP this
(nfennatioo applies la urlrata. l*oi fcauei contcnttaiiesu of Dilute (IP. tf* information provided here are for
guidance and the specific use of protective clothing and equipment should be based on the rvA assessment approach
in accordance with good safety #«d indiotrol hygiene pnncipJas.
Kanowin Lfaalu for fawttftorv Prelect fan for GF:
Unprotected Workers:
Cftjwoeitoxmgfo*1) Tlmtldinta
Las* than or equal to 0.0000}' (T hours
Up to or (ess than 000012 2 bouts'
Protected Worker*;
Tjpe of Respiratory Protection Worn (based on monitoring mulls):
1 M40 Military Mask. CBRN NfOSH Approved Pull Face Air Puttying Ropfratoi
Cwwrnrtwumtt-'m1* TtoMLUmlo
Not greater than 0.0015 Up to ¦ hours1
Greater than 0.0015 and leu than 0002 Upto6houts
Greater than 0.002 and less 0i«n O.OfttS l*p to 4 bouts
Mixture OF-Hex Page 7 of 10
Not greater than 0 0025 Up to 15 mimrtes4
2 Pressure Demand Supplied Air Rerptrator wfih FuO Pace Respirator
ExmJjiwI**
000003 to 005* TimetjaiiftiUbekeptatamimmumro
peribrm the operation, and will be dictated
by the local Heat Stress Program for
pcrtonal protective equipment and clothing
3 Pressure Demand Supplied Air Respirator with Full Pace Respirator in combination with an Auxiliary
Self-contained Breathing Apparatus (SCBAt orjurl SCBA
CgnttnffttiMiimgflrX. Time Limits?
Greater than 0.05 These concentration* should be expected
only in emergency situation*. Operations
thoofd not be conducted at these
concentrations
1 Aa an Mir TWA average
J Man mum continuous time at this concentration. Equivalent to S-frr TWA. Source Implementation Guidance
Policy for Revised Airborne Exposures Limits for OB, OA, (3D, OP. VX, it HD. and HT, Dcpt of Army. Office of;
the Assistant Secretary o the Army Installation* and Environment, 18 June 2004 See Table 3
* Canister for M40 Mash must be changed out «er> 6 hours of use
4Based on APF of 50 times the STEL (0.00005 mgfai'x which is a 15 minute TWA Only 4 excursions to this
concentration with a 60 minute interval between each one is allowed during an S hour workday.
* The Immediately Dangerous to Ufa and Ilea) A Value
'For SCBA wearers, thnc Itmfl isionstrsroedtyliftoftheair cylinder (niaxnrano of JO to 45 minutes) For Air
Supply wearers, time limits should be kapt to a minimum. Should use of the auxiliary SCBA be oecessarv. time
limit will be constrained by the life of the breathing air cylinder, and egress from the area most be performed bdbre
its ex piratic*
Personal Respiratory Protection for Hexane: If the exposure limits are exceeded and engineering coatrols are not
feasible use a NIOSH approved respirator.
VentRatlen System:
A system of local and/or general exhaust is recommended to keep employee exposures beiow the Airborne Exposure
Units Local exhaust ventilation i» generally preferred becauau h can control the cttovhotts oTtfw contaminant at its
source, preventing dispersion of it into the genera) work area
Special: Chemksl laboratory hoods will have an average inward face velocity of 100 linear Cfct per mftwlt (ffpm)
-A 20Hwtth theveloqfr many point not deflating from the average free velocity by more than Existing
laboratory hoods will have an tawatd ftee velocity of ISO llfcm -*.'-20W Laboratory hoods wfil be leased such that
drosj-drofls do not exceed 20% of the Inward ftce velocity. A viteal perfbrnuoce test ttsiog nnoke-ptoduciDg
devices will be performed n cssessirtg the ability of the b*od to contain agent
Other: Rtdraria&on or exhausl afr flmn Chetrtkal areas 11 proMbiied. No connection between chemkal arm and:
other areas through ventilatoe system is permitted Emergency hadcup power ts necessary Hoods should be tested
at (east srtsimncaJly or afar modification or reamtcntsec operations. Operatioea should be peitxmed 20
Mixture GF-Hex Page 8 of 10
-------
centimeters inside hood fact
Prolrrlive Chim for Neat CF: Butyl Rubber Glove M* apd M4
Norton, Chemical Protective Glmi Set
Derontaminate nd cbangt butyl rubber gloves in tbe event of contact wfih liquid Hexane since Hexaite degrades
butyl rubber
Eys Protection: At etntmtnum safety glasses with fide shields will be ivom. For splash hazards use gogglti and
face shield. Maintain evewasb facilities tn writ mi
Other Pretertiva RqotpmeQt! Per laboratory operations, feeommend wearing Impeivlous protective closing
loctoAng booti. gloves, lib coat, ipnm or coveralls. u appropriate. to prevent skin contact. In the case ofaspHI.
the omuanim protective eJothing should be donned after the ntt hu bran evaluated
Monitoring: Available monitoring equipment far agant CiF a Tosk UqaMt
This mixture is considered a Toxic Liquid fbr Dilute OF coacentrttiofti greater than 0 14 mg'ml and le*» Hian nr
equal to 2.0 mgrml
Proper Stripping Name: Toxic by inhalation liquid, flammable, n.o • (Hruae and Cydohexyl
met^yiphosphonoftuondaie;
I'N ID Number: UKU84
Dot Hazard Ctais: 6 l,). Packing Group I, tahalatton Harard Zone B
DOT Label: Poison Inhalation Hazard or Toxic Inhalation Hazard See 49 CFR I72.400i(fljfl) for
exceptions to unit packaging labeling and 173 7(b) for other exceptooos when material is transported by
Technical Escort Unit*.
NOT£ "Poison" and Took" ait used interchangeably for all markings, labels and placards in
continental l*S transportation "Toxic" is required for international transportation
Dot Marking: Toxk by inhalation liquid, flammable. n.o i. iHcxanc and CytHihrxyl
methyiphosphoanfluoridatc) IN? JW, Inhalation Hazard Zone B
DOTPUeartf: Poison Mialation Hazard or Toxic Inhalation ItecfnJ
Emeigcney Aertdent Pretaotkns aad Procedures: See Sections IV. VII and Vm
Precautions To B» Taktn In Thmsportarton: Mofurvehtdt»will beplac4rdedpcrD0D4SCQ.9-R Oiiverswiil
be given fbll information regarding shipment and comfitLoos ia caseof anemcrgrttcy AR 5M deals spccHlcally1
with the shipment of chemical agents
Hie Edgawood Chemical Biological Center (ETBCJ. Department of the Army bdieves that tbe data contained i
herein are actual andaratbereaiilisaf the tests amduvted by ECBT experts Tbe data ate not to be taken as a
waicaofr et cepieientatioft for whichJhe Pepanmtnl of the Amy or ECBC assumes legal responaabihty T^eyare
offered solely for consideration Any use of tins data and information contained in this MSDS must be determined
by the user to be in accordance wtlh«ppficgb|cFcflcmI. Stole, endtocri laws and regtriatioas.
Mixture GF-Hcx Page 10 of 10
-------
fflfa'M&j Mi
Mixture DbttUcd Mustard (HD) tn Hcxanc
Rented: II Jafttl007
Section 1 - General Information
Menttfoctorer*s AMnni
l/.S Anhy Edgtfmod Cfttrnks! Biological Center (ECBC)
ATTN. AMMRD-fcCB-CB-CR
Aberdeen Prtmug Ground. MD 21010-5424
Business Phoor 410-4)6-4411 or 4414, Monday through Friday dune# ike hour* of 6-03 AM to 41c PM EOT
CAS Registry Number?: Nooe known for the mixture
Chemical Name: 8tM2-chloroelhyl) sulfide and I tesane
Trade name end synoayms:
FID m e: Distilled Mustard ftHesaac
CMHenlielluii: DfartcHD sofaaions vary a eoncemratioc from lO.OagofHDpcr arillflterof Hexane toO I4C
W of HD per aiDiUter of Hexaoe
Section III - Physical Data
ApptMnna tad Oder of HD: Pate yellow to dark bftmn oily liquid; eolostes* when pure. Gaffic4ilceor
horseradish odor.
oiw&lm
NOTKj Due to low cuneentntioni of agent ia Dilute HD the remaining physical properties given are that* of the
Hextn*. for eddiiioaa) HD properties tefet to the neat HD MSDS
Appearance aad Odor: Colorless liquid with a mitd solvent type odor.
BoHldf Point S> 760 am Hgt 69' C
Yapec PrtUOT (mm Hgfc I5l (HjO-1): O.o6
Viscosity: 031 mPas® 20* C
Mvlmilir Wri^n (|teo))t lti.ll
Freeztog/Melttag Pointt -95* C
Section IV - Fire and Explosion Data
NOTE: Di ltd led Mustard is not knows to be flanmebie Information given for fire and explosion date comet from
the flammable solvent, Haxane
Ptast) Potat -7 *P (-22 *C?
Lower Esptovfve Limit: 1.1%
Upper Esptostrc Unite 7 5*4
AutoignltlooTefoperattrre: 437 • F (125 #C)
Extlngutshfag Medte For smell fires, use dry chemical powder. CO} and aIcofad«mi stint foam Waterway ba
ineffective Avoid me of eetingiulshlng methods that will ceuso splashing or spreading of irtveat
Special Fire fighting Procedares; All persons not engaged in extinguishing the fire should be Immediately
evacuated (torn the erca. Fires should be contftaed to prevent spreading to uncontrolled trees Wttn responding to
a fire alaim in buildings or (rets contaWog polveats, fliO'flglrtiag paraonad should wear Ml QmAghter protective J
clothing jftanw resistant) during file fighting and fire rescue operations Rcspiiaimy protectkm b reynred Positive
pressure. fidHkoe piece, NIOSH«approvcd wf*contemed breathing appeiatus (SCBA) wD bo worn where there a
danger ci oxygen deficiency and often directed the flro chief or dttaaeal accident/bodem (CAl) operation!
officer. Use wtler spray to cool fira-exposed containers
¦lOTfc Do not bceafhe fanes. Skbi contact with mustard most be avoided at aR times Although the Are may
destroy most of the agmt. can austftlQ be taken to eesura the agem or contaminated ttqpidi do not father
eontammaJe other aress or sewers Contact wrilh lipoid HD or vtpws can be fcal.
Uftasoal Are and Explosion Hazards: Vapor may tt*vd considerable distance to source of ignition and flash baek.
Container explosion may octar uader Ore conditions. Material is lighter than water end may baspreed by the use of
weter
Mixture 1 ID-Hex Ptgc 2 of 10
-------
Section V - Health Hazard Data
Airborne Exposure Limits (All.):
AKI, for RD2:
Worker Population Limit f "STEL 13>min TWA r
AVPL) R-hr TWA' ' mgrW
og/m'
0,0004 0.003
Genera) Population Limit
(GPL> 12-hrTWA'
rag/511
b.00002
There values ceo be found in din DA, Office of the Assistant Secretary, Installations and Environment mcaio.
subject Implementation Guidance Poficy for Hew Airborne Bxpotures Lntot* for 0B. OA. (cwiitngbli«crs)anda1)cvtaii&g ogent producing cytotoxic octooti on the
hematopoietic (blood-forming) ttssttes. which arc especially sensitive. The tate of detoaiftcatlon of IfD in rite body
if very slmv ami repeated exposures produce a cumslative effect
Signs and Symptoms: The acute sign* and symptoms fbftowing muflard exposure are not immediate; they ore
delayed m appearance. The duration of the latent penod snd tbe decree ofii^wy are both dependent en the severity
of exposure as well as orgenx affected The delay of omct t* dotr-dcpeodenl end may range from hours to days
The latency period for ocuttr (eye) effects is shorter than thai for other tissues.
MDdeye cxpotwe symptom* ro mostard include InlUnrmaiian. eon}unaititts possibly with laaimiticm. grittincsiin
the eye. and eiythema (reddening) of the lids md eery unrivn. Severaiymptotm includephotophobia,
MephaiospaTm. paw. corneal etorioo, mtt*, conjunctival vaaculftriietion, ulceration and coma) opacification
Mixture HD-Hox Page 3 or 10
(blindness)
Skin exposure to mmtard vapor is marked by delayed appearance Mild symptoms inchrde erythema, edema,
itching, burning end pain Severe symptoms indade vesication or Mirteo Liquid mustard exposure on tUa may
tesxdt in an area of gray»white neaota skin surrounded by erythema and vesication
hi halation of mustard vapor cancel damage primarily to the naiopharygea). larygea! and tracheobronchial mutosa
Respiratory symptoms to mustard vapor vary in degree of onset and intensity related to the degree, of exposure.
Mild symptoms to the airway include hoarseness, fofhmmarion of the respiratory mucosa, congestion, coughing and
edema Severe qrmptomsindudonKrosta, sloughing nf the mucon and chcmtca) pneumonia Repeated exposures
ot prolonged inhalation can came bronchiectasis or chrome bronchitis.
Gaitroimesrint} symptoms of intense mustsrd exposure include nausea and vomiting.
Like other alkylating agent*, systemte absorption resuHt biigury so the bone marrow, lymph under, and spteen
pfoduciq^eiijiepenta and thrombocytopenia Other syitetnic effects incfetde: fsver. CTitr between tbe right and left hmg) TUotors '
observed have been of squsmoua (scale like) or undifferentiated (dterated) ceil types Conxtder the possibility of
skm cancer because of the frequency of this lesion in aiumal studies Since uiKW msiiard agem is clmilar la he
effects to nitrogen mustafd. which has been assocsated wiA human leuLomie, this iSsesse mi^fl abo he expected to!
occur in humans chronically exposed ro mustard.
Toxicity Values:
Vsoor flxhotafWOndar^
0 (Mild) - 25 niB-minW
ECrtO (Severe)2 » 100 BUHnWn*(M
LCtSQ »1000 mg^nU^m
Ymr ifffffltffiwwt11
ETt50 (VCId) " 50 mg<*>tirtn'
EftSO (Severe)9 w 500 mg-min/in1
LCtSO •» 10000 mg-nvn^n''
Ltouid tPercntaoeoas>
EDS0 - 600 mgftO kg otan
LO50 * 1400 mg^TO kg man
1 Estimates for lohtUrfoa vepor exposure are bated on a minute volume (MV) of 13 IHcti Tbe exposure time is 2
minutes The coocenwittHlme profile fin lethality is described by the toxic load model (CHi) The toxic load
exponent (n) for lethality is 15
1 Bawd on oeidar (eye) eflecta.
% Rooenaanatyili of atchivai human dean has tndleaied thai this value muy b*7$ rog-miaW.
4 Personnel are masked
1 Values for pereutaneooa vapor ere far Doderetetempaiwures (IS eP and below) Tboeffeetrve dosages An hot
tempenourcs (95 T and above) win be lets by at least a fktor of 2
Mixture !ID-Hex Page 4 of 10
-------
Emergency end Pint Aid Procedores for HD:
Vapor Eipetorc ImroedEatefy leave area of contamination Vapor-ex posed mustard agonl cawaltjes ihould bo
deeoataminaied b} removing all clothing in • cfcaa air environment and shampooing or riosiaii the hiir to prercnl
vapor ofT-gassing.
Uqofd Exposure: fmixitdlet«t> (cava are* of cunumuttflon Wash the slrm surface and htir in warm or hot water
at lent three timet The rapidl physical temotal of a drcmico) agent ii essential. Scrubbing of exposed skin with a
tniTbnixhoihrtalesfsdiscoureged because skm damage may occur and may increase absorption of agent Use
liquid soap (dispose of cftntfincr after use sod replace), copious amounts of water, and mibJ to moderate fKction
Midi a stogfe-ttse sponge or washcloth in the fust and aecond wade* The thhd wash thould be a rtnw with copious
amounts of warm at hot water. Shampoo can be ased to wash the hair U warm or hot water 11 not available, but
cold water rv use cold water Do not deity decontamination to obtain warm witcr. Iwopetmbsible alternative
skin decontamtaants include (he M24I Skin Decontaminating Kit (SDK) nd a 0 }*« sodium hypochlorite solution
(NOTE. The aw of the M291 SDK end'or O.S* t sadhire hypochlorite on skin is appropriate in situation! where soap
and water mav not he as efficacious in physically removing particular types of mustard agents, each as those used tn
cetiam research end development leborstorica. Nother soap and water, 0 5% sodium hypochlorite or (ha VQ9I
SDK have been shown to be mora efficacious than the other fbr physicoUy removing every type of mustard agent
from the skin ) Based, theo5%sodram hypochlorite shouldbe applied mthmild to modcrateftfctton.witha
single-use sponge orwasttdoih in the first and second washes The iMrd wash ihould be a raise to ronrve sny
residual sodium hypochlorite with copious amounts of wirm or hoi water
Eye Contact; Imaedtatfty leave area of contaiasttstSen and begin flushing cyei, mucous membranes, or open
wounds with nenle saline or water. Flush (he eyes Immediately wtth sterile saline or water by offing the bend to
the side, pulling the eyeWi apart wtlh gloved finger* and pouring slowly mlo the eyes. A Morgan tea* may auo be
used fbr continuous eye irrigation
Ingestion: Do not induce vomiting. First symptoms are likel) to be gastrointestinal Seek medical attention
Immediately. Do not hnnfle vomited material to erotd farther contamination.
Inbatattom (Fbreatbmgcs difficult,, adminisur oxygen If breathing has stopped, gJvearaficud respiration Mooth*
to*mouth resusdtaaon should be used when appro* ed mask-big or uxygen delivery aystetro are not available Do
not use mouth-to-mouth resosdtatton when (fecial contamination it present Seek medical attention tanmedlatety
Braltb-BaiirdDaU for Koaat:
Target org*n(s)t Central nervous system, eyes. skin. respiratory system, and peripheral nervous system
Kfrtets of Exposure
Inhalation: Inhalation of vapors irritate* (hs respiratory tract. Overexposure may cause lightheadedness nausea.
headache, and blurred vtstco Greater exposure may cause muscle iwakncss. numbness of the extremities,
IngesttoiK May produce Abdominal pain, nausea Aspiration into htngs can produce severe long damage and is a
medical emergency Other symptoms expected to parallel inhalation.
SUn Contact May cause redness, irritation, with dryness, cracking
Byt Contact: Vtpors may casta irritation. Splashes may causa redness and pan.
Qtrocte Exposure: Repealed or prolonged skin contact may defat the skin and produce imtation and dermatitis.
Chronic inhalation may causa peripheral nave disorders and central nervous system afters.
Mixture HD-Hex Page 5 of 10
Aggravation of Pvr-exIsttntCottdHlflttsi Penoos with prt-extmng skin ditordars or eye problem* or Imp ii red
wxpimory function may be more susceptible to (be effects ?f the substance May affect tbe developing firms
Emergency sad Ftnt AM Procedures?
luhataltom Remove to fresh air If not breathing, give artificial respiration Ifbreathing it dHEtaril give oxygen
Coll • physician.
Ingestion; Aspiration hazard. If swallowed, DO NOT INDL'CE VOMrTINO Never give anything by month lo an
unconscious person Oct medical attention immediately
Skin Coaiact: Remove any contaminated clothing. Wipe off excess ftum (tin. Wash skin wtth soap and water fbr
at least 15 minutes. Oct medical attention If hritmon develops or persists
Eye Contact: Immediately flush eyes with plenty of water for at least I < minutes, lifting lower and uppei eyelids
occasionally. Get medical attention immediately
Section VI - Reactivity Data
Stability: The mjxtrahaibccn.fcond to be stiWe in sealed containers fbr op to 12 months at or below ¦t'C. Lie
of the mixture and storage above 4* C will hasten the degradation of tbe HD within (he mixture.
ReartMty Data fbr OD:
Decomposition Temperature: HOT
Rate of Hydrolysis: HD on or under water undergoes hydrolysis only if dissolved Tbe rate ofHD hydrolysis is
controlled by the rate of mass trsulcr and is very alow.
Hydrolysis Products: Hydrogen chJoitdc. tlnodiglyvol and sulfomura Ion aggregates one of which is also very
tOJUC.
Haaordons totytncrboHon: Docs not occur
Reactivity Data far Beaaoei
Intompxtibflityi Strong Oxidizers
Daanrdottf Poly marts afioct Will not occur
Hazardous Decomposition: Emits toado fames of Ceibon Monoxide, Carbon Dimlde and acrid smoke
CoodHtaas to avoid: Igmtion totnees, excess heal and efectncsl spark.
Section VII - Spill. Leak. And Disposal Procedures
Steps to be Taken In Case Material Is Released or SpOted: Evacoste area. Wear appropriate protection
cqripmeai as specified in section (See Section VIII). Keep unprotected and ooneeessaiy personnel ftom entering
area See Section V for emergency and first aid instruct!uas
Shut off all sources of ignition. VestUote area of leak or spUl Use inert material to absorb spUl
-------
und or wrth> Decontaminate wi th copious amounts of a S*» bleach solu&on Scoop up All materia? and pi acq In a
DOT approved container Cover (he contents with copious amounUof a 5JV bleach jotutiop After seating,
deconuminase the nrtetirar eomatoer and labeled according to EPA and DOT regulations All leaking containers
will be over packed with wbcttt (tg vermiculitc} placed between the mtcrior end exterior containers.
Decontaminate and Ubcf acrcnttng to JBPA and DOT regulations Dispose of decontaminate according to Federal,
flats, and locallaws. Conduct genoil area monitoring to confirm ibat the atmospheric concentrations do not exceed
the AKLi (Sac Sections V and VIII).
Waste Disposal Method: Open pit burning ot burying ofHD or Items containing or contaminated with HD in any
quantify Is prohibited. Waste HD otd associated deccmembwtioa solutions may be Resource Conservation and
Recovety Act (RCRA) regulated hazardous wastes d« to a State lifting of the chemical agent, or the characteristics
ofthewnsle. fotnefeds contaminates An evaluation of the Federal and State waste disposal regulations must be
conducted to determine th* appropriate disposal method.
Section VffT - Snecial Protection Information
NOTE; The information pro\ ided hrre is lake* from the neat HD MSDS At the highest concentrations of DUute
HD this informadoa applies in whole. For lower concentrations of Dilute HD, the information prov ided here are for
gmdance and the apeeifie use of protective clothing and equipment should be bated on ibe risk assessment approach
ts tcenfdance xvrth good wJety and industrial h)gtcfie principles
Einosmr Limits for Rwufrntorr Pmterffan for HP
Unprotected Workers:
Concent ribon fmn/Wl
Lest than or equal to O.P0041
Up lo or less than 00016
Frotrrtrd Workers:
Type of Respiratory Protection Wont (based on air monitoring results)
I. M40 MHitajy Mask. CBRN NIOSH Approved Full Pace Air Purifying Re'ptraw
104)03 Tune limit wiH be kepi af a minimum to
perform the operation, and will he dteMed
by the local Hett Stress Program for
personal protective equipment sad clothing1
? Pressure Demand Supplied Air Respirator wtlh Fall Pace Respirator
Copcewtraiton Ima'nr) IlHW.Uroitl*
0.0004 to 0.7* Thne limit will be kept at a minimum to
perform the opetation, and wit) ha 6cuted
by the local Heat Strcii Program fox
personal protective equipment and dothtng
•pm^Iimitj
Shows
2 httirr
Mixture HD-Hex Pgge 7 of 10
3 Preistue Demand Supplied Air Respirator wirb Full Face Kesptrotor in combination with »n Auxiliary
Self-contained Breathing Apparatus (SC'BA) or jus! SCBA
rqncytifiation lme/m3± Time Limits?
Oreater than 0.7 These concentrations should be expected
only in emergency situations. Operations
should not be conducted at these
concentrations
1 As an 8-ta TWA average"
• Maximum confauoos time ai this cuoccntrattow Equivalent to g*hr TWA Source Implementation Outdance
Policy for Revised Anbornc Limits for GB, GA, GI>, Of, VX, II, HD, and I IT, Depl of Army, Office of the
Assistant Secretary of the Aitny Installations «sd Environment. IIJune*Qtt4 SeeToHeS
*'fhe M40 mask may be and for escape from snvironmcnts contenting contcntnuions above thc^TBL ThcM40
mask may used for ronline entry with teal-time monitoring for the STEL and historical monitoring for the WPL
The M40 mask will not be used for rouftne protection above rhe STflL or in die absence of WPL monitoring ,
4 For SCB A wearers, time limit Is constrained by lift of (he air cylinder (maximum of JO to 4 « minutes). For Air
Supply warns, time limits should be kept to a minimum. Should use of the auxiliary SCB A bo necessary, time
(unit will be constrained by the life of the breathing air cylinder, and egress from the area most be perfbrmed before
it« expiration,
* *Hie Immediately Dingerous to Life and Health Value *
Personal Respiratory Protection fer Homk If the exposure limits ore exceeded and engi see ring controls are not
feasible me a NIOSH approved respirator.
Vmrthtkp System:
A system of local and/or general exhaust Is recommended to keep employee exposures below the Abba me llxposure
Dmita. Local exhaust verthlanon ts generally preferied because it can control the emisswns of the contaminant at sis
source, preventing dsspetston of it into the general work area
SpecM: Chemical Isbocatory heeds wiU have an average inward fiftco velocity of 100 linear feet per minute flfpm)
2Wk with the vdocrt) at ait> powt not deviating from the overage foeevelocitv by more then 20^«. Existing 1
laboratory toads will hsvo an toward face velocity of ISQlf^m-AKA*. Laboratory hoods wtfl be located tueh that
crns-drafli do not evceed 20% of the inward (ace velocity A visual performance wst utmg smoke-fioducing
devices will be peifmuied in assessing the ability of (he hood to contain agent
Other: Recirculation or exhaust air ftomchemical areas ^prohibited No connection between chemical ttan *itd
other areas through ventilation system Is permitted Emergency backup power is necessary Hoods should be tested
at least sermannuiDy or after tnodSfttahoa or maintenance opcta&oos Operations shoutd be performed 20
centimeters inside hood fttce
Protective Gloves for Kent HD: Butyl Rubber Glove Ml and M4
Norton. Chemical Pratcctta Glove Set
Decontaminate and change butyl rubber gloves in the evert of eouact with liquid Hexane sioce Hextne degrades
butyl rubber.
Eye Protection: At a minimum saftty glasses with aide shields will be worn. For splash hazards use goggles and
bee shield. Maintain eyewash fadlittes in work area.
Ollwr Protecthri Equtpmegfc For hbotabaiy openfams. rrccremcnd waring impendoas protective clothing
lodudmg boots, gloviss, lab coat, apson or co%endls. as appropriate, to pcevent skin contact la the case of a spill,
the minimum pzotecove doddntf should be donned after Hie site has been evaluated
Mixture HD-Hex Page fl of 10
-------
Monitoring: Available monitoring equipment Tor tgtni I ID i» the Ml \tv deteclot paper. detector ticket
M2S6*M256A1 kits bubble*. Depot Are* AVrKfonfloriPB System (DA^MS}. Artoma+«d CoTrtimjous Air
Monitoring S>itennACAMS), Real-Time Mooter fRTM), Demititaruatioo Chemical Agent Concentrator
(DCAC) M8-M4), M1AI/M4 JA1, CAM-MI, Hydrogen FUme Photometric Emission Director (IfYFfUH tho
MinUmce Chemical Agent Mooter (M1NICAM). and die Real Time Analytic*) Platform (RTAPi
Section IX - Special Precautions
Frctauf teas To Be Taken In Handling and Storing: When handling mixture the buddy s> tun should be
incorporated No «oioia®p, eailng. or drinking In an«t cortaimng BgCTti/sofvtntJ it permitted Container* should
he periodically inspected for leaks Stringent control ova all personnel practice* must be cxcrnied.
Decontaminating cqotpmeitt *rfH be ceowmcsdy loeated Hxiti must be designed to permit rapid o tcuaiico
Chemicd shower*, eyewash stations, perianal cteaoliMSifeciMte* *nd nreexth»3ttJ*tierimusi He provided Wort,
hands before meals and, as appropriate. shower thorough)) wtth special attention gtvee to hair. fttt. neck. and hands
usmg plenty of soap and water before leaving at the end of tha wort.de).
Other FrectioHom: Mixture should br stored In as explosion proof refrigerator with a lo» temperature obrm
Keep tightly ctated Keep anav from heal, ipirks and open name No smoking Take precautionary measures
against static discharges.
For addtf oriel information see *AR The Arm> Tone Cheimeal Agon Safely Program ^ "DA Pom J8S-6I,
Tome Chemical Agent Safety Standards" and "DA Pant 40-I1, Occupational Health Gtrtdcttnet fbr the Itafcotion
and Control of Occupational Hvposute to Mustard Agents H, HD. and HT*. and DA Implementation Guvdsrrcc
Potrcy for New Atlbome Exposures Limits for CB. GA. OD, CP. VX H. HD, and HT dated 18 June 2004.
Stttton X -Trumnortatitm D»t»
Shipping as a flammable Uqotd:
Tfris mixture Is considered • Flammable Liquid fbr Dilute KD concentrations st or belovt 2.9 mgfail.
Proper Stiippiog Nave: FlannmjM* liquid*. Toxic nor (llexanr and Dis-t2(2* for other exceptions when material is transported by
Technical E-soort Units
NOTE: 'Posson" and "Toxk" are used interchangeably for aft markings, Ub*>a and placards in
commtnul t'S transportation. "Toxic" is required fbr international transportation
Dot Marking: Totieb) inhalation liquid, AammsMe, n o s (Hexane and Bit- (2-cfctoroc0ty1) sulfide)
1 fbr consideration Any use ofthts data tnd information contained in this MSDS most bt determined
by tha iwer to be in aceordanee with applicable'Federal. State, and local law» and regulanoas.
Mixture HI>Hex Page 10 of 10
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- Mixture Lethal -Nerve Agent (VX) fnltoprapyl Alcohol
Rerfetd: 12 /not 2007
Section I ¦ General Information
\JS Amy Edgewoud Chemical Biological Cow (ECBO
ATTN: AMSRD-ECB-CB-CR
Aberdeen PtoWngOrouttd, MO 21010*5424
Besiiim Phone: 410-436-4411 or 4414. Momiaythrough FrWey doling the hour* of «:00 AM to4J0PM EDT
Chwltil Naati 0>bdiyl*SH2Htil*oprapytainliioethyt) mcfhyl phosphonothiolafe end Isopropyl Alcohol
Trmd« mm* eod synenynw
VX in solvent
CAS ARM VX
ROTEOihifeVX
Cfcrokat Ffemflr Mhrtwe of a sulfonated oqpMptapfeortii compound and QammabJt solvent
MotrcntarFttrtntdaVX: C,,Hj»NOjP$
Motor alar Fbnmsfa Ifopropyt AleoMs CiH.0
KFFA 7W Signal: >i« itch . 4
|1krniHiM*T\ • 1
Special-0 '
Section II -Ingredients
lagridimi/Namr VX A hopiopyl Alcohol
Concentration: Dihite VX ceoccntratteas vaiy fiom 1.0 tug of VX pet craffiBt«r of taopiopyf Afcoho! to 0.012 MS
of VX per millditcr oTlfopropyt Alcohol
SetHon HI ¦ Physical Data
Appearance and Odor of VXs Coloriett HquM whee pore Odorless when pure
ROTKt Put to low uwiccniiartoas ofagent fa Dilute VX (he rtmatfring physical properties given are those of the
liopfopyl Alcohol. far adfitional VX properties refer to the neat VX MSDS.
AppctmctaidOdBn Calorie** tiqoid with a ndld robbing alcohol odor.
Boflldg Falsi fi? 760 on Bg} IT C
VaporPressure (aimHg): 44£2$*C
Vapor Density (Atr-I): 2 I
SpcctneCrarll)r(H|0«l): 079
Vhcottaft 127 mfas @ 20* C
Molecular Weight (bAmO: 60 1
Frtcsiag/Metting Point; -*9* C
^Hon H,Y • Fire and EspHwtoffl PhIb
NOTEi VXb not known to be flammable taftxmatfoagivao for fire and explosion data come* ftatn the
flammable, aafrem, Isopropyl Alcohol
Plasti Fetal; 54 *F (12 *C)
Lower Eapfaalvc LlmH: 2.0%
Upper BxptoetvcUate 11.7K
AntotgaftJoa Tfcmperaiort: 750 * F (J99 *C)
Ssttngulsfctag Media; For small fttaa, use wsfcrsptajr, dry ctemtcal powder, OOj and fam Avoid tue of
extmguiihiDg methods that will cause tpJastoog or spreading of solvent
SpeetalPtreFlgptflagtroeodurca: AD pervom not engaged m cxtfugolsMns (h« fire should be inaiedlatBJy
evacuated fan the area. Rro shoold be costaloed tt prevent spreading to uncontrolled areas. When responding to
a fire tUrm in buttings or areas conufatlag soh-entf. 0r*-flgteta8 per«oond tfcooM wear ftillftivftgtaer protective
ttoMm (flame tdmaO tofan fin ftghWng and Bw retail operations fteeplratory yintdm 1« repaired ?oiHtve
pressure, fafl-ftca piece. NIOSH-approved «df
-------
Woriccr PopoEition Limit
(WPL) 8-hr TWA 1
rna/m'
STGL 15-minTWA : -
mgftn1
IDLH' ' Generd Population Lieut
rag/nT (QPL) 124v TWA *
\ msJn
0.000001
000001
0.CO? I 0.0000006
1 Xhnt vitro cm be foond to tin DA, Office of the Assistant Seqettiy. UmillatfoiH aid Environment memo,
wbiecr trcpiemcfltatton Guidance Pobcy for New Aljtome Exposures Until* fa GB, OA, GO, CP.VX.1iHD.
cad HT. II June 2004.
1 To date. the Oticaprionil Safely cad Health Administration (OSIIA) have not promulgated & penniniMe exposure
concentration for VX.
For Isepropyt AlwM)
threshold Limit Vdot (TV«V)i The TLV for Isoptopyl Alcohol if 400 ppm or 9S0 mgrnT as an eight-hour ttme-
weighted outrage (TWA)
PEL: 400 ppm or WO nff m5 as a TWA
IT* mixture i* aol Used by (he International Agency fbr Research on Cesser 0ARCX American Conference of
Governmental Industrial Hygieeists (ACCtHX Occupation*) Safoy end Health Administration (OSHA). oc National
Toxictfogy Program (NTP) at a eardnogen
The mhctsre should be treated n » podsoaooi and ftammcbfr liquid. Pemnmd should avoid contact with iho
mixture end u*e appropiiste typetAevdsof protective defiring tsd equipment
NOTK There cs presently no tonicity data for the mixture of VX and bopropyl Alcohol The information provided
hef« is taken from the not VX MSDS.
Rentes of Entry: Primtry route ofeaby Tot VX is often thought to be tiqmdcontsd with skin Although, it is less
volatile (han other nerve *gent«,Hisextiemcty potent and even veiy low concentrations el airborne vapor ere
estmnely hazardous. Additionally, a secondary rouie of entry can be through fagpieon
0fcrta of Exposure: Nerve areata are readily absoibcd and are hazardous through all route* of exposure The
most prominent physiologies! effects results from the Inhibition of ChB in the central nervous system. The result
produce! effects htdodmg mona. rtrinonhea, broacboconstrktion, Increased gutrotatestrad mottthy, imacta
ftscwrqlattoaa. wdawu. flaeetd paralysis. dMtiaafty hi concentrating. amkfy, 1 mora ma, resdeisnen, depression of
the respiratory cemar. eenvidahms aad death
Stun* and Symptom*: The onset of the signs ead symptoms following exposure to nerve agents may occjr within
seconds, minutes, or hour*, depending upon comtntratov dotage, and mute of entry, as weft as the type and
physical state of the nerve ageiti
VX poia both a liquid ond vapor hazard to the unprotected worker. The flnt noticeiWe vapor effects are rmons,
tight chest andfor rtdnoRbee Thesa signs can occur in the absence of measurable ChE Inhibtti on in the Wood.
Later, mild signs and symptoms of vapor exposure tadudacoqjimctivaifaieciioti, pais behind the eyes <£oa**t*ct
blurred vision and excessive salivation.
Moderate signs and symptoms ofvapor exposure may include mild »gn» and symptoms of exposure ptur increased
shortness of breath, coughing, nfeeeifaig, vdumtams bronehonhea. nausea. vomiting and diarvfcea
Severe signs and symptoms of vapor exposure may include moderate signs and symptom* of exposure plor
gem lalmd weakness or fesciculstloasftwitLhliig. tots of cunsriouinmi (withto seconds), cacvufsiora (witfrio
mtnotes), severe myiiatuiy distress, Oareid paeatyna and apnea.
Mixture ofVX-IPA Page 3 of 10
Effects &om liquid percutaneous exposures to nave agents are flower to develop and slower to reach their peak |
when mcnpajcd to vapor exposures of the eyes o» itipiratory trad MlM signs and symptoms of Uqutdoove agent
sklx exposure indudc tocafaaed iwuetlng at the aits of expoeure and toe musde ftsdcutanowftwitdiing (NOTE;
Miosis is net an early sign of hqoidskm exposure Thia if only true fbr exposures that mdode contact with airborne
vapor with the eyes. In eases of nerve *9ent exposure not Involving vapor contact with tfca eyes, miosis may be tarn
of the last effects to occur fa such eases, the dotages ofMqtrfd exposure which products miosis aro not significantly
Afferent itantefhddom.) I
Toaklty Values!
Vapot Ctnhata"
EC150{Threshold) - 10mg«into
ECtSO (Severe)-1 * 2i mn-nm/m*
(.1130* I JO mg^nra/m'
Llairfd
EDflO ¦ 2 ffgHO kg man
LD30 • S mgTTO kg mSnT
1 Reccm data indicate that this value ma>' be as low as 0 04 mg-mirVm'
* Severe effects alio mdadr death.
4 Pcrsowcl are mariced.
' Values fl>r percutaneous vapor are for moderate temperatures (IS *F and bdow). The effective dotages fbr hot,
tempera turn (IS T end above) wW he lets by at teas! a fetor of 2
* Threshold refers to a sttgkl ChE WtfWfion
1 Rem modefing of the VX Data btfeste* that the LD30 could ba as low as 2 ogiTO kg man.
Emergency and First Aid Fieceduiest
MOTEt When seeking Btodttal attentoo, inforni mcdwl persoend that this is an organophmphems mixture
Vapor Caposuret Immediate^ leave area of contamination. Vapor exposed nerve agent casualties shouM be
drrmiiniiiiiintrd by rcawvfng all dotting in a dean air envhowneal sad ihampodag or rinnftg the hair to prevent
vapor off gassing.
UqsM SUn Eaposum Leave area of cootritimtien as quiddy as possible. Remove dethtag in a dean air
environment and wvsb At sJdo surface and hair b warm or hot water at least dnee times. Hia rapid physical
removal of a chemica) agent is essential. Scrubbing of exposed skin with a stiff brash or britfe* it dhmuraged,
because ikindamago may occor and may Increase absorpfhm of sgent Use Hquid soap (dispose of container alter
use and repteoe): copious aaouam of water, and mild to moderate fHcdon with a singlMMe spoage or wnsheloth is
the first and second washes The third wash should be a rinse with copious amounts of warm or hot water
Shampoo can be used to wash the hair, tfweitn or hot water it not evaUabt*, but cetd water it. use cold water. Do
not delay ifcecwHamiiuiUiwi toobtain warm water. TW> penmsrihle dtemative akin decomammantsHidude the
M291 SMn PecontsmlmtlngKit (MMCl wd a 0J%sodhBB hypochlorite totetton. (JfOTC: That»eoftheM29)
SDK andtor OJH sotfium hypoehlorita on skin la appropriate in rituadons where soap and water may not be as
efficadeus to physically removing parttader types of nmve agents, sudi as those used In certain research aad
Mixture ofVX-IPA Pigt 4 of 10
-------
development lahoratonci Neither soip and v%ve. 05% todmm h>pochlorHe of to M2*) SDK have been shown
to be more efftcacioo* than lb* o&a'fbr physically removing evesy type of nerve agent from the slda) |fimd,rhc
0.5H eedum hypochlorite should be applied with mild to moderate faction. wiA a single-use sponge or waxbdotfa
tn the first aad second washes The third wash should be a rime to remove any residual aodwm hypochlorite with
copraa animals of win or hot water
Eye Contact: Immediately leave amaofcomammcHcm end begin R«s!d»g eyes, timeout meo&tanet, or open
woeads with sterile saline or water Flush Ifie cyn hnmc£«tdy with sterile taflne or wtttr by tilting cfce hrmd to the
¦We. ptfftng the eyelids apart with gloved fingers and pouring slwdy brio the eye* A Morgsa kns may alio be
used for cwutauoui eye irrigation, Alfeough miosis (penpoforeg of the pupils) may b» «n earty sign of agem
exposure, en ngectkmwDlnotbe administered when reiosi is (he only ago present Instead. tha individual will be
takes bwdMily to a medical treatment facility Tor obsexvstioa
tm» and sWn
Effects of Baposvre;
fnbelaifeo: Exhalation of report intute* Ibe respiratory trod. Exposure to high cmcentratkms Ms a narcotic
effect, producing symptoms of dinini. drowsiness. tmdeche, staggering, tmcomttoomm and possibly death.
Ingestions Con catrse drowsiness, unconsciousness, end death Gastrointestinal pain, cramps, nausea, vomiting, and
diarrhea may alao resab
SktaiCantaet: May cause Irritation with redness and pain. May be absorted through [he skin whh possible
syilcmtt effect*
EyeCooteei. Vapors cease eye Irritation Splashes cense severe irritation, possible corneal bums aed eye damage.
Ovoak Capeaore: Chronic effects of exposure to isoptopyi alcohol have not been repotted In humana, except for
rare Instances flfcctema and akin teasttzathm
Aggravation of Pre-eatateg CbodMoosi Perwns with pre«existiag tkm diaordetior impaired liver, kidney, or
pulmonary function may be mare ttseeptiMe to the effects of this agent
Emergency and Ftrrt AM Procedures;
Mixtve of VX-VPA Page 5 of 10
Inhatettoo! Remove to fresh atr Ifool breathing, give artificial respiration. If b*ej]hmgisdifOcYitl. gK-e orygen
Gel medical attention iromedialdy
logeittani Aspiration hazard. Give large amounts of water to drink Never ghre anything by mouth to en
tmcomdoDi pet ton. Oct medical atirnflen Immediately.
SUa Canted: In cm of contact, {huh skin wttfc plenty of water. Remove contamiosted dothlng and iheea. det
medtcal aid if irritation dwdtyj cod persists Wash clothing before reuse
VyeCbutMfc hnmedbtdyflusheyeswKhpleitfyefwnterfcrflitcaft IS nbute»,Uffing lower and upper eydtib
occasionally. Get medteal attestion lomcdIatel>.
Sectton VI • RcacOvrtv Data
StaMltjr* TJm mixture has been found to be stable in sealed containers for op to 12 months at or below 4" C. In
d*Ae mixture and storage above 4* C wffl hasten tho degradation of the VX within die nrixtore.
Reaell>lty Data far VX;
DeroajpwWoa Tetaperafore; t| »• 502 days ^ 7I*C; t: .«41 days^ I05*C; f)|-J4 J hr@ 130X; t,:- lOfv
@ I70T. t|, - 1.6hr® 200T.t,t>-4mbsi* Umlnln
l2JMNaqn;tu-ia0mlernO.25MNaOa't|}-3limolaO.IOMNaOH:t«i-3ihrHiOOlM KaOH andl,. •
60 hr is pure water.
Hydrolysis Prodecta: VX Tiydrofyssi via three different pathways (F-S, P-O and OS), wtnch vary significantly
with temperatnre and pH. At pH below 12, die F-O bond cleavage pinh produces ethyl methylphosphonale (EMPA)
and the toxic S^Z-nfibopaipylamiBOCtbyl] meihyipfaapiwaothiolata ten (BA 2192V At room tempermfttre CA 2192
reactislowtjf wfthOir(EA 2192. t|) • 7.4 days in I OMNsQH]. evrnmstty producing (ess toxic protects Ust^g
tn equimolar ratio of VX and water st elevated temperatures appears to reduce Stc persistency of EA 2172.
Hazardous Fetymcrteafao: Does not occur
Reactivity Data for laopropyl Alcetnt:
Stabttityi Stab)* ondcr orAoafy coodrtiottt of oyo and storage Heat end rnnfight can contribute to instability
Hainrdo—PMomposltton Prodoets: Carbon Aoxide and carbon monoxide may form when heated to
decomposition
Haaardoaa Polymerfaatton: Will not oecnr
loroorptribOMet: Heat, flame, itroeg oxwfian, acetaldehyda, acids, chtorine. ethyleoe oxide, hydrogen patladHrm
combinadoe, hydrogen peiomdesidftino acid eon^ination. potassium teit»buloxid» hypochteous acid, isocyenstes,
utrolorm, phoagena. aluminum, oleum and petchloric add
Ceodttiom to AvoUt Htet flames, igrideo seurcei and ineempatiblei.
SecUon VII - SirflL Leah. And Dfapoial Prottdurta
Mixture ofVX-IPA Page « of 10
-------
Steps to b* Tekro (a Cm* Material U Mtfd or SpOWd; Evacuate area, Wear appropnate protection
e«fcr TWA. Source' tmplemefltatfoa Outdance
Policy for Revised Alrboma Exposures Lunto for OB, OA, OD, OF, VX H, HD. and IfT. Dept of Army. Office of
the Assistant Secretary e the Aiwy butaltaliofts and Fjivfroamenl. 18 JtnwJ004 See Table 4
3 Canbter for M40 Mask own he changed out «wy 6 bona of use.
4Butd oa AFFof SOtrmesthe STEL(000001 whiehisa ISmiauteTWA Only one excursion to ibis '
conocBtratkn la allowed during aa 8 hour woritdap.
1 The tnmediataljr Dangerous to life and Health Value.
* For SCBA wearers, daw btntt » cooslrlined by life of the air cylinder (maximum of 30 to 45 irewtes). For An-
Supply weajcri. time limits should be kept to a minimum. Should ase of (he auxiliary SCBA be necessary, time
hmit will he constrained by the fcfc of thebrcadriagwr cyfmder, aad cgreas from tbe area must be performed before
Hs expiration
r
20ft with the velocity et any point not deviating ftats the average face velocity by more than 20%. existing
laboigtay hoods wiP hare an inward face velocity of ISO tffrm -»/- 20% Laboratory hoods will be located sath thai
crasvdmfts do net exceed 20H of the i award ftoe velocity A vtaul perfbrmancetesttmagsmoke-produciiig
devices will be performed m assessing the ability Of the hood to coetain agent
Othen Recirculation or exhaust aft ftom chemical areas liprofctbfad He conntcAni between chemicd areas and
otftei areas through ventilation system is permitted. Emergency backup power Is necessaiy Hoods should be tested
at leartretmanmony or after modification or maiutmaw»a operations. Operitiocs ihedd be perfbnned 20
eentimeten ittride hood face.
Protective CSoves far Heal VX: Butyl RulAerOloveMJ end M4
Norton, Chemical Protective Ctove Set
Mixture of VX-1PA Ptge 8 of 10
-------
Eye Protection: At a mfciimam safety glasses with stde shield* wilt be For splash hamdi use goggles «wl
(ke shield. Maintain eyewash facilities m worfc area.
Otter hofnOw Eqaipaot For tiboruory operations. recommend wariog impervious protective clothing
includinggloves,Ubcoat,apronorcoventii,a*appropriate,lopreventdunconuci lathe case of a spill, the
minimum protective etaffcfag ihould be domed after Hie «te has been evaluated
Maaltnelug. Available moiitorfng equipment for agent VX is the Mt/M9 defector paper, detnetar ticket
M256/M256AI Ida, bubbler. Depot Am Air Monitoring System (DAAMS), Atmrmtffd Coohiudas Air
Monitoring System (ACAMS), Real-Time Monfo* (R7M). Dcntilltariiatfon Chemtcal A gem Concentrator
(DCAC), MS/M4J. MSAt/M4)A I, CAM-MI. Hydrogen Flame Photometric Cmisnoa Detector (HYPED), the
MMstorc Chemical Agent Monitor (MIMCAM), and to Real Hate Analytical Platform (MAP),
Section IX - Special Precaution*
Precautions Tb Be Taken la Baodling asd Storing: Whan handling mi cure the buddy system should be
incorporated No fmefctag, eating, or drinking in areas containing agenta/tatveirts it permitted Containers should
be periodically Impacted far leak*. Stringent control over ad personnel practices must be eeercised
Decontaminate^ equipment will be convcmqtfy located. Exits math* deugned to poiiut rapid wacoerton
Chemical showeri. eyewvsh (tattoos, penonal ctesnflncss fkcittttes. aod flreextmjjjtslwrs must be provided Wash
hands before meaU and, ot appropriate, shower thoroughly with special attention five* to hair, Ifcce, ate*, end hands
using plenty of aoap and water before leaving at the end of the workday
Other Prreactions: Mixture should be itored in an explorioa proof lefflgaiptor with a tow temperature a!arm
Keep tightly dosed Keep away ftom heat, sparks. and open flame Notmofang. Take precautloRaiy measures
against ttatic discharges.
Par itftfoRal mfomtion see 'All J15-61, The Army Toxic Chemical Agent Safety Program," "OA Pan
toxk Chemtcal Ageat Safet) Standards." end DA Pkm 40-8, Occojuftcrtal Health Otndehncs for the Evaluation
aod Control of Occupational Exposure to Nerve Agents OA, GB. GD, and VX"; and DA ImpkiiKUtaduc Guidance
Pofky for No* Airborne Exposures Lmn'ti for GB, OA. GD, GF, VX, H, HD, and HT dated 18 June 2004
Section X - Transportation Date
Proper Shipping Nmm: Flammable Liquids, Toxic, n.o a (bopropyl Alcohol and 0-Elhyl-S-<2-
flisopiopylaoinucthyl) methyl phosphonothiolate)
UN ID Number? UN 1992
Dot Itaard Cteaa? ) & 1. Parking Oroup I
Del Label: Flammable LtqutdTTojoc
Dot Marling; Flammable liquids. Toxic. n.o a (bopropyt Alcohol and 0-Ethyl-S-(2-*isopropytambioedQf|)
metftyi phosphnnothMale) UNI992
Del Placard: Rammefefe and Pottte if placard i* required
Bamycy AeeMcot Pretentions and Procedares: See Sections IV. VII and Via
Pretentions To Be Taken to Tramportatlum Motor vehicles wfll be placarded per DOD4S009-R. Drivers will
Mixture of VX-IPA Page 9 of 10
be given Ml information regarding shipmentand conations in case of an emergency Aft tt-6 deals specifically
with the shipment of chemical agents. j
TtaEdgawoodCI»eretcalB
-------
PARTICIPANT FEEDBACK FORM
FORT MEADE CWA EXERCISE
AUGUST 20, 2014
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PARTICIPANT FEEDBACK FORM
Exercise Name: ESC CWA Exercise Exercise Date: August 20,2014
Participant Name:
Title:
Agency:
Role: Player Controller
Evaluator .Observer
PART I: RECOMMENDATIONS AND ACTION STEPS
1. Based on the exercise today and the tasks identified, list the top 3 issues
and/or areas that need improvement.^
2. Identify the action steps that should be taken to address the issues
identified above. For each action step, indicate if it is a high, medium, or
low priority.
3. Describe the action steps that should be taken in your area of
responsibility. /
-------
Who should be assigned responsibility for each action item?
4. List the equipment, training or plans/procedures that should be reviewed,
revised, or developed. Indicate the priority level for each.
PART II: EXERCISE DESIGN AND CONDUCT
1. What is your assessment of the exercise design and conduct?
Please rate, on a scale of 1 to 5, your overall assessment of the exercise relative to the
statements provided below, with 1 indicating strong disagreement with the statement and 5
indicating strong agreement.
Rating of Satisfaction with Exercise
Assessment
Factor
Strongly
Disagree
Strongly
Agree
a. The exercise was well structured and organized. 1 2 3 4 5
b. The exercise scenario was plausible and realistic. 1 2 3 4 5
c. The documentation used during the exercise was 1 2 3 4 5
a valuable tool throughout the exercise.
d. Participation in the exercise was appropriate for 1 2 3 4 5
someone in my position.
e. The participants included the right pepple in terms 1 2 3 4 5
of level and mix of disciplines.
-------
2. What changes would you make to improve this exercise?
Please provideany recommendations on how this exercise or future exercise
could be improved or enhanced.
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