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Chemicals-in-Progress
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Office of Pesticides & Toxic Substanc
(OPTS)
Vol. 4, No. 3	May 1983
This news bulletin is intended to inform all persons concerned with the Toxic Substances Control Act (TSCA) about
recent developments and near-term plans. For further information or to request copies of documents mentioned,
write the TSCA Assistance Office (TAO), (TS-799) EPA, Washington, D.C. 20460, or call toll-free 800-424-9065 or, in
Washington, D.C., or from outside the continental United States, (202) 554-1404.
REGULATORY & REQUIRED ACTIONS
TESTING OF CHEMICAL SUBSTANCES
AND MIXTURES ... SECTION 4
Section 4 of TSCA gives EPA authority to require manu-
facturers or processors of chemicals to test the toxic ef-
fects of a designated substance. To require testing EPA
must find that the chemical may present an unreasona-
ble risk; that there are insufficient data available with
which to perform a reasoned risk assessment; and that
testing is necessary to generate such data. A test rule
may also be based on an EPA finding of substantial pro-
duction and exposure to humans or the environment, in
addition to findings of insufficient data and need for
testing.
Under section 4(e) an Interagency Testing Committee
(ITC) was established to recommend chemicals to EPA
for priority consideration. The ITC can designate up to
50 chemicals or categories of chemicals for testing and
EPA must respond within one year by starting rulemak-
ing under section 4 or giving reasons for not doing so.
EPA Makes Available Data Submissions
EPA has received, and made available for public inspec-
tion, data submissions on chlorinated paraffins,
2-chlorotoluene and alkyl phthalates. The two catego-
ries of chemicals and the one chemical had been previ-
ously recommended to EPA for testing by the ITC. In
each of the situations after the ITC action, a producer or
an association of producers presented EPA with a
testing plan. The plans were accepted by EPA in lieu of
issuing a section 4 test rule because of EPA's view that
this approval would lead to the more expeditious devel-
opment of test data for the involved chemicals and the
Agency's concerns were met by the testing plans. The
EPA notice of the receipt of the new data appears in the
March 23, 1983, Federal Register (48 FR 12124). The
data on chlorinated paraffins were submitted by the
Consortium of Chlorinated Paraffin Manufacturers.
Chlorinated paraffins are used primarily as flame
retardants and plasticizers. Occidential Chemical Corp.
submitted the testing data on 2-chlorotoluene. The sub-
stance is used as a solvent for agricultural pesticides
and is a general solvent replacement for
1,2-dichlorobenzene. The Chemical Manufacturers As-
sociation, through its Phthalate Esters Program Panel,
is conducting testing on the phthalate esters and alkyl
diesters of 1,2-benzenedicarboxylic acid, which are pri-
marily used as plasticizers.
Section 4(f) of TSCA requires EPA within 180 days after
receipt of test data or other information that indicates a
chemical substance or mixture may pose a significant
risk of serious or widespread harm to human beings
from cancer, gene mutations or birth defects to: a) initi-
ate appropriate action under sections 5, 6, or 7 of TSCA
or b) publish a notice saying why the risk is not unrea-
sonable. The 180-day review may be extended for up to
90 additional days for good cause.
EPA Reviewing MDA
As announced in a April 27, 1983, Federal Register no-
tice (FR 19078), EPA has initiated a 180-day review of
4,4'-methylenedianiline (MDA) and is asking the public
to submit all available relevant information about the
chemical. An EPA decision on MDA will be published on
or about September 12, 1983, unless there is good
cause to extend the review.
EPA is accelerating review of MDA because laboratory
tests by the National Toxicological Program have found
the chemical to be carcinogenic in both rats and mice.
Based upon EPA's review of the NTP study and its own
evaluation of exposure potential, EPA concluded that
1

-------
MDA could pose a significant risk of serious harm to
workers manufacturing and processing the chemical.
MDA is an intermediate used to make other chemicals
and plastics, and is not known to be present, as such, in
any consumer products but may be present in industrial
products such as coatings and rubber additives. Thus,
EPA's concern is limited to the workplace. If the use of
this chemical requires regulatory action, EPA intends to
work jointly with the Occupational Safety and Health
Administration (OSHA) of the Department of Labor.
EPA estimates that a total of 230 to 450 million pounds
of MDA is produced each year in the United States. The
National Institute for Occupational Health and Safety
estimates that 2,500 workers may be exposed during
MDA's manufacturing and processing. There are cur-
rently no mandatory worker exposure standards for
MDA.
EPA is unsure as to the exact number of present pro-
ducers. From public records, the following companies
were identified as having produced MDA in the past or
as possible present producers or importers.
Firm
Production Location
Allied Chemical Co.
BASF Wyandotte Corp.
ICI Americas Inc.
E.I. duPont de Nemours
and Co.
Ciba-Geigy Corp.
Dow Chemical Co.
Mobay Chemical Co.
Olin Corp.
The Upjohn Co.
Uniroyal
Rubicon Chemicals, Inc.
Miller Stephenson
Moundsville, WV
Parsippany, NJ
Unknown
Deepwater, NJ
Belle, WV
Importer
Midland, Ml
New Martinsville, WV
Baytown, TX
Unknown
LaPorte, TX
Naugatuck, CT
Geismar, LA
Unknown
Under section 4(e) an Interagency Testing Committee
(ITCI was established to recommend chemicals to EPA
for priority consideration. The ITC can designate up to
SO chemicals on the list at any one time to which EPA
must respond within one year by starting rulemaking
under section 4 or giving reasons for not doing so.
ITC adds chemicals to list
In its twelfth report (May 11, 1983) the ITC added 5
chemicals to its list for priority consideration and desig-
nated all for response by EPA within 12 months. The
following tables contain the latest ITC recommenda-
tions, the section 4(e) Priority List to date and EPA's dis-
position of ITC Recommendations.
CHEMICALS ADDED IN THE TWELFTH ITC REPORT
ChemicallGroup
Recommended Studies
Designated for response within 12 months:
Methylolurea	Health Effects: Short-term
(CAS No. 10000-82-4) genotoxicity; toxicokinet-
ics; long-term bioassay, if
indicated by results of
genotoxicity and
toxicokinetic testing.
Calcium naphthenate
(CAS No. 61789-36-4)
Cobalt naphthenate
(CAS No. 61789-51-3)
Lead Naphthenate
(CAS No. 61790-14-5)
2-Phenoxyethanol
(CAS No. 122-99-6)
Chemical Fate: Abiotic and
biotic persistence, includ-
ing dissociation; trans-
port, including soil
mobility.
Health Effects:
Carcinogenicity;
mutagenicity;
teratogenicity;
toxicokinetics; reproduc-
tive effects.
Ecological Effects (de-
pending on the results of
chemical fate tests):
Acute toxicity to fish and
aquatic invertebrates;
toxicity to plants;
bioconcentration.
Health Effects: Reproduc-
tive effects;
teratogenicity; short-term
genotoxicity; subchronic
toxicity.
Recommended but not designated for response within
12 months:
None	—
THE TSCA SECTION 4(e) PRIORITY LIST
MAY 1983
Chemicals and Groups Designated for Response
Within 12 Months
Entry	Date of
Designation
Alkyl epoxides		Oct.	1977
Aniline and bromo-, chloro-,
and/or nitroanilines		Apr.	1979
Aryl phosphates		Apr.	1978
Bis(2-ethylhexyl) terephthalate . Nov. 1982*
Calcium naphthenate	 May 1983
Chlorinated benzenes, mono-
and di-	 Oct. 1977
Chlorinated benzenes, tri-,
tetra-, and penta-	 Oct. 1978
Cobalt naphthenate	 May 1983
Cresols 	 Oct. 1977
Cyclohexanone 	 Apr. 1979
Dibutyltin bis (isooctyl
maleate)	 Nov. 1982*
Dibutyltin bis (isooctyl
mercaptoacetate)	 Nov. 1982*
Dibutyltin bis (lauryt marcap-
tide) 		Nov.	1982*
Dibutyltin dilaurate		nov.	1982*
1.2-Dichloropropan	e		Oct.	1978
Dimethyltin bis (isooctyl
mercaptoacetate)		Nov. 1982*
1.3-Dioxolan	e		Nov. 1982*
Glycidol and its derivatives		Oct. 1978
Halogenated alkyl epoxides		Apr. 1978
Hydroquinone 		nov. 1979
1.
2.
3.
4.
5.
6.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
2

-------
21.
Lead naphthenate 	
. May 1983
22.
Mesityl oxide	
. Apr. 1979
23.
4,4'-Methylenedianiline	
. Apr. 1979
24.
Methylolurea 	
. May 1983
25.
Monobutyltin tris(isooctyl


mercaptoacetate) 	
.. Nov. 1982*
26.
Monomethyltin tris(isooctyl


mercaptoacetate)	
. Nov. 1982*
27.
2-Phenoxyethanol 	
. May 1983
28.
Quinone 	
. Nov. 1979
29.
4-(1,1,3,3-Tetramethylbutyl)
Nov. 1982*

phenol	

30.
Tris(2-ethylhexyl) trimeilitate ..
. Nov. 1982*
Other Recommended Chemicals and Groups

Entry
Date of Recom-


mendation
1. Carbufuran intermediates Nov. 1982*
•The dates of designation and recommendation have been re-
vised to reflect when the revised lists were actually delivered
to the EPA Administrator, rather than the dates when the re-
ports were prepared.
EPA DISPOSITION OF ITC RECOMMENDATIONS
CUMMULATIVE REMOVALS
FROM THE TSCA SECTION 4(e) PRIORITY LIST
MAY 1983
Chemical/Group
1.	Acetonitrile
2.	Acrylamide
3.	Alkyl phthalates
4.	Alkyltin compounds
6. Antimony metal
6.	Antimony sulfide
7.	Antimony trioxide
8.	Benzidine-based dyes
9.	Benzyl butyl phthalate
10.	Biphenyl
11.	Butyl glycolyl butyl phthalate
12.	Chlorendic acid
13.	Chlorinated naphthalenes
14.	Chlorinated paraffins
15.	Chlorobenzotrifluoride
16.	Chloromethane
17.	2-Chlorotoluene
18.	o-OiBnisidine-based dyes
19.	Dichloromsthane
20.	Diethylenetriamine
21.	Ethyltoluene
22.	Fluoroalkenes
23.	Formamide
24.	Hexachloro-1,3-butadiene
25.	Hexachlorocyclopentadiene
26.	Hexachloroethane
27.	Isophorone
28.	Methyl ethyl ketone
29.	Methyl isobutyl ketone
30.	Nitrobenzene
31.	Penylenediamines
32.	PolycMorinated terphenyls
33.	Pyridine
34.	o-Tolidine-based dyes
36. Toluene
36.1,1,1-Trichloroethane
37.1,2,4-Trimethylbenzene
38.	Trimethylbenzenes	48 FR 23088 May 23,1983
39.	Tris(2-chloroethyl)phosphite 47 FR 49466 Nov. J, 1982
40.	Xylenes	47 FR 56392 Dec. 16,1982
'Removed by the Committee for reconsideration. Seven indi-
vidual group members were subsequently designated in the
11th ITC Report (Ref. 12) for priority consideration.
EPA PROPOSES TESTING ON INDUSTRIAL CHEMICALS
The U.S. Environmental Protection Agency has pro-
posed regulations requiring that several industrial
chemicals be tested to determine whether they cause
environmental problems or pose a health risk to work-
ers and consumers.
EPA is proposing the testing on the recommendation of
an Interagency Testing Committee, a body of scientists
representing eight Federal agencies which was estab-
lished by Congress under the Toxic Substances Control
Act (TSCA). The chemicals are ethyltoluenes (ET),
trimethylbenzenes (TMB), and biphenyl.
ET and TMB are components of crude oil, gasolines, pe-
troleum products, and industrial and consumer sol-
vents. Small quantities of both chemicals are used as
industrial intermediates. EPA is proposing to require
testing of a petroleum refinery product containing ET
and TMB because it has been determined that almost all
exposure is to this product rather than to the individual
chemicals.
Biphenyl is used, in combination with other chemicals,
as a dye carrier and heat-transfer fluid and is used to
produce alkylated biphenyls.
Acting Assistant Administrator for Pesticides and Toxic
Substances, Don R. Clay, called the proposed rules "an
example of EPA's commitment to take prompt and ap-
propriate action on chemicals designated for considera-
tion by the Interagency Testing Committee." These
chemicals were on the 10th list of chemicals submitted
by the ITC to EPA. Lists have been submitted to EPA
since 1977, with the Agency meeting a May 10, 1983,
deadline for taking action on all chemicals on the list.
The Agency is acting under the Toxic Substances Con-
trol Act and proposes to require firms making the hy-
drocarbon mixture containing ET and TMB and biphenyl
to be responsible for conducting the testing. EPA's
analysis of industry production and sales data shows
that testing costs would have no significant economic
effect on the firm.
Affected companies are encouraged to cooperate on a
single test program for each chemical, thereby splitting
the costs.
In addition to the test rules, EPA proposed a negotiated
test agreement for formamide, used as a chemical inter-
mediate and as a solvent in petroleum production, soil
stabilization and for porous-tip writing instruments. Al-
though there is no current U.S. production of
formamide, BASF Wyandotte Corporation imports be-
tween one and 11 million pounds of it per year. BASF
Wyandotte has agreed to perform the testing which the
Agency determined was needed for formamide.
EPA's new test rule proposals will appear in the Federal
Register. A public meeting on the proposals will be held
in Washington, D.C., if requested.
Federal Register Notice
47	FR 58019	Dec. 29,1982
48	FR 724	Jan. 6, 1983
46 FR 53775	Oct. 30,1981
46 FR 5466	Feb. 5, 1982'
48 FR 716	Jan. 6, 1983
48 FR 716	Jan. 6, 1983
8 FR 716	Jan. 6, 1983
46 FR 55005	Nov. 5, 1981
46 FR 53775	Oct. 30,1981
48 FR 23080	May 23,1983
46	FR 54487	Nov. 2, 1981
47	FR 44878	Oct. 12,1982
46	FR 54491	Nov. 2, 1981
47	FR 1017	Jan. 8, 1982
47 FR 50555	Nov. 8, 1982
45	FR 48524	July 18,1980
47 FR 18172	Apr. 28,1982
46	FR 55005	Nov. 5. 1981
46	FR 30300	June 5, 1981
47	FR 18386	Apr. 29,1982
48	FR 23088	May 23,1983
46	FR 53704	Oct. 30,1981
48 FR 23098	May 23,1983
47	FR 58029	Dec. 29,1982
47 FR 58023	Dec. 29,1982
47	FR 18175	Apr. 28,1982
48	FR 727	Jan. 6, 1983
47 FR 58025	Dec. 29,1982
47 FR 58025	Dec. 29,1982
46	FR 30300	June 5, 1981
47	FR 973	Jan. 8, 1982
46	FR 54482	Nov. 2, 1981
47	FR 58031	Dec. 29,1982
46	FR 56005	Nov. S, 1981
47	FR 56391	Dec. 16,1982
46 FR 30300	June S, 1981
48	FR 23088	May 23,1983
3

-------
COMMENCEMENT OF MANUFACTURE NOTICES
. . . SECTION 5
The final PMN rule (48 FR 21722) says "if EPA does not
take action to regulate a substance during the review
period, the submitter may manufacture or import the
new chemical substance without restriction, as soon as
the notice review period expires. The submitter must
notify EPA by tetter when manufacture or import be-
gins. " Upon receipt, EPA adds the new substance to the
TSCA Inventory.
EPA Publishes Final PMN Rule
A final rule establishing premanufacturing notice
requirments (PMN) and review procedures under sec-
tion 5 was published in the Federal Register on May 13,
1983 (48 FR 21722). The rule becomes effective July 12,
1983. EPA has been operating the PMN program under
an interim policy. To date, the Agency has received
more than 2,300 PMNs.
PMN submitters are required to use the PMN notice
form published with the final rule. The final form only
requires information necessary for the initial review of
a chemical. If EPA decides it needs more detailed infor-
mation, it will request the submitter to provide the in-
formation during the review period. If necessary the
Agency can also obtain further data under section 5(e)-
The final rule also clarifies requirements for submitting
test data and other health and environmental effects
data. For data that appear in the open scientific litera-
ture, the PMN submitter need only give the citation.
Eliminated from the final rule was a provision for for-
mal supplemental reporting (by the PMN submitter and
others) during the notice review period, notification re-
quirements for processors of exempt chemical sub-
stances, and the requirement that notice submitters
Contact their customers for information for the PMN.
The final rule also clarifies when a submission is incom-
plete and how the submitter is notified of the
incompleteness.
COMMENCEMENT OF MANUFACTURE NOTICES
Under section 5(a)(1) a person who intends to introduce
into commerce a chemical substance not on the TSCA
Inventory must notify EPA at least 90 days before be-
ginning manufacture or import. Listed below and on the
next few pages are the latest commencement of manu-
facture notices EPA has received.
NEW CHEMICAL SUBSTANCES FOR WHICH EPA HAS RECEIVED COMMENCEMENT
OF MANUFACTURE NOTICES
(tine* publication of tho March IMS Chontleata-ln-Progrcw Bulletin)
PMN no.
80-60
80-199
80-223
80-327
81-51
81-64
81-226
81-261
81-331
81-464
81-500
Submitter
CBI-Confidential Businfttt
Chemical Identification
G^G«n«ric Nam«
Morton Chemical
CBI
Do
Do
Do
Do
Morton Chemical
GBI
Do
Goodyear
Sherwin-Williams
Polymer of: methyl methacrylate; methyl acrylate;
butylacrylate; 2-hydroxyethyl acrylate.
G Methyl, aminoheteropolycycle.
1, 6-Hexanediol, terephthalic acid, neopentyl glycol, tri-
mellitic anhydride, adipic acid, and isophthalic acid.
G Toluene diisocyanate blocked prepolymer.
G Polymer of tall oil fatty acids, neopentyl glycol,
pentaerythritol, isophthalic acid, and benzoic acid.
G Polymer of neopentyl glycol, adipic acid, trimellitic an-
hydride, and an aromatic aliphatic ester.
Polymer of acrylic acid, acrylonitrile, butylacrylate,
2-hydroxyethyl acrylate, and vinylidene chloride.
G Amine derivative.
G Acrylic modified alkyd resin.
G Alky! styrenated acrylate terpolymer.
2-dodecyl-9~H-thioxanthen-9-one.
FR Cita-
tion
Do=Ditto
45 FR
25131
(4/14/80)
45 FR
60003
(9/11/80)
45 FR
61019
(9/15/80)
45	FR
83020
(12/17/80)
46	FR
16319
(3/12/81)
46 FR
16933
(3/16/81)
46 FR
31940
(6/18/81)
46 FR
34409
(7/1/81 >
46 FR
38578
(7/28/81)
46 FR
47855
(9/30/81)
46 FR
60147
(10/9/61)
4

-------
81-512
81-591
81-621
81-625
81-633
81-656
82-59
82-131
82-147
82-173
82-174
82-233
82-250
82-263
82-272
82-277
82-319
82-327
82-330
82-359
82-386
82-419
82-450
82-458
82-483
82-485
82-518
82-562
82-566
82-667
CBI
American Cyanamid Co.
CBI
Do
Do
Do
Do
Do
Do
Do
American Cyanamid Co.
CBI
Do
Do
Do
Ashland Chemical Co.
CBI
Do
National Starch and
Chemical
CBI
Do
American Cyanamid Co.
CBI
Do
Ashland Chemical Co.
CBI
Sandoz Colors and
Chemicals
CBI
Do
Do
G Substituted heteropolycycle.
G Nitrogen-containing organic sulfide.
G Polyester of propanediol, adipic acid, phthalic anhy-
dride, aromatic aliphatic ester.
G Blocked isocyanate.
G	Hydroxy alkenyl borate.
G	Halogenated nitrotoluene.
G	Aromatic disazo dye.
G	Zinc-containing alkenyl carboxamide.
G	Organorhodium complex.
G	Borate esters-mixture.
G Substituted acrylamide polymer.
G Organic salt of phosphorus.
G A mixture of Naphthalene disulfonic acid, [azoxy bis
[(substituted-phenyl azo)] bis substituted, and its so-
dium salts.
G A mixture of the sodium salts, lithium salts, and mixed
sodium/lithium salts of naphthalene disulfonic acid,
[azoxy bis [(substituted-phenyl)azo) ]bis
[substituted-.
G Heterocyclic-alkylphenyl azo suostance.
G Polymer of aliphatic and aromatic diacids and an ali-
phatic diol.
G Alkyl oligoglycosides.
G Hydroxy, amine-substituted anthraquinone.
G	Polyvinyl acrylate).
G	Polyester resin.
G	Metal complex of disazo aromatic acids, sodium salt.
G	Acrylamide-acrylate copolymer.
G Amino alkyl alkoxy silanes.
G Polymer of a vegetable oil derivative, alkane diols and
a carbomonocyclic anhydride.
G Polymer of acrylic acid and acrylic esters.
G Chlorotriazine modified copper phthalocyanine, sodi-
um salt.
G Metal complexed substituted aromatic.
G 1-Naphthalenesulfonic acid, ((((triazin)
amino)disulfo)azo)-, trisodium salt.
G Heteromonocycle, substituted.
G Heteromonocycle, substituted.
46 FR
50840
(10/15/81)
46 FR
58177
(11/30/81)
46 FR
60981
(12/14/81)
46 FR
61505
(12/17/81)
46	FR
62312
(12/23/81)
47 FR 1019
(1/8/82)
47 FR 5329
(2/4/82)
47 FR 8674
(3/1/82)
47	FR
10073
(3/9/82)
47 FR
10900
(3/12/82)
Do
47 FR
15406
(4/9/82)
47 FR
16403
4/16/82)
Do
Do
47 FR
17666
(4/23/82)
47 FR
19781
(5/7/82)
47 FR
20852
(5/14/82)
Do
47 FR
23552
(5/28/82)
47 FR
25400
(6/11/82)
47 FR
26234
(6/17/82)
Do
Do
47 FR
31063
(7(16/82)
Do
47 FR
34187
(8/6/82)
47 FR
36469
(7/8/81)
Do
Do
5

-------
82-587
Do
G
Alkylbenzenesulfonic acid compound with dialkyl fatty
amine.
47 FR
39241
(9/7/82)
82-588
Reilly Tar and Chemical
Corp.

4-(1,1-dimethylethyl)pyridine.
Do
82-589
Ashland Chemical Co.
G
Cresol novolac modified [methacrylate epoxy ester].
Do
82-602
CBI
G
Mixed glycol oligoesters of mixed dicarboxylic acids.
Do
82-630
Do
G
Unsaturated alkyl fatty amine.
47 FR



39884
(9/10/82)
82-631
Do
G
Unsaturated amine adduct.
Do
82-644
Do
G
Alkylene ether diol.
47 FR
41165
(9/17/82)
82-651
Sandoz Colors and
G
Metal complexed substituted [aromatic salt].
Do

Chemicals


82-657
CBI
G
Sulfonated vinylic polymer
Do
82-661
Do
G
Modified polyurethane.
47 FR
42151
(9/24/82)
82-662
Do
G
Modified polyurethane.
Do
82-663
Do
G
Modified diol.
Do
82-667
Naarden International
G
Cyclic aldehyde.
Do
82-670
CBI
G
Oxirane polymer of isocyanic acid ester.
Do
82-671
Do
G
Vinyl chloride-ethylene copolymer.
Do
82-674
Interox America

Hexa-aquomagnesium (II) bis(2-carboxylatomono-

82-680
83-44
83-51
83-89
83-74
CBI
peroxy-benzoic acid).
2-propenoic acid, 2-hydroxyathyl estar, polymer with	47 FR
2-ethyl-2-(hydroxymethyl)-1, 3-propanediol, -hydro- 43160
w-hydroxypoly loxy-1, 2-ethanediyl),	(9/30/82)
5-isocyanato-1- (isocyanatomethyU-l, 3, 3-trimethyl-
cyclohexane and 2 oxepanone.
82-683
Do
G
Halogenated ketone
Do
82-691
E.I. duPont de Nemours
& Co.
G
Ethylene interpolymer.
47 FR
44608
(10/8/82)
82-698
CBI
G
Aminosulfur compound.
Do
82-701
Sandoz Colors and
Chemicals
G
Aromatic disazo dye.
Do
82-702
Do
G
Metal complexed, substituted aromatic azo compound.
Do
82-703
CBI
G
Reaction product of coco glycarld**, •utfur, and
-DO'


polyalkylene-substituted phenol condensation prod-
uct with aldehyde and mixed amines.

82-704
Do
G
Reaction product of carboxylic acid, sulfur, and
Do

polyalkylene-substituted phenol condensation prod-
uct with aldehyde and mixed amines.

82-708
Do
G
Ester of diazo-napthoquinone.
Do
82-709
Do
G
Dibasic acio ester of monohydric alcohols.
Do
83-3
Do
G
Disubstituted propane.
47 FR
46371
(10/18/82)
83-4
Do
G
Substituted propene.
Do
83-5
Do
G
Substituted alkanoic acid ester.
Do
83-6
Do
G
Substituted lactam.
Do
83-7
Do
G
Substituted lactam.
Do
83-8
E.I. duPont de Nemours
G
Substituted alkylsulfonic acid.
Do

& Co.


83-9
Do
G
Substituted alkyl poiysulfide.
Do
83-13
CBI
G
Amine modified dimethylpolysiloxane.
Do
83-19
Do
G
Substituted benzoic acid.
Do
83-20
Do
G
Substituted phenoxy toluene.
Do
83-21
Hach Co.
G
Trisubstituted azo naphthol disulfonic acid
Do
83-24
CBI
G
Substituted pyridine.
Do
83-32
Do
G
Modified polyester polyurethane from substituted
47 FR
3M Co.
Sandoz Colors and
Chemicals
CBI
Do
Polymer of [2 propanoic acid, 2-methyl-,
2-[[(perfluoroalkyl)sulfonyl]methylamino; ethyl es-
ter with butyl methacrylate and lauryl methacylate.
G Alkoxytated alkyl amine.
G Mixed C„ dicarboxylic amino [alkyl amines].
G Polymer of styrene, alkyl acrylates and substituted alkyl
msthacryiates.
47066
(10/22/82)
Do
47 FR
49072
(10/29/82)
47 FR
50338
(11/5/82)
Do
6

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83-90
83-91
83-92
83-105
83-108
83-119
83-127
83-128
83-242
82-258
83-261
83-269
83-270
83-271
83-290
82-291
83-294
83-295
83-382
83-383
83-384
83-385
E.I. duPont de Nemours
& Co.
American Hoechst Corp.
CBI
American Hoechst Corp.
CBI
Do
Do
Do
Do
Do
Morton Chemical
CBI
Do
Do
Do
National Starch and
Chemical Corp.
CBI
Do
Do
Do
Do
Do
G Polymer of polysubstituted alkyl acrylates.
Polymer of tall oil rosin, gum rosin, paraformaldehyde,
calcium hydroxide, phenol.
G Reaction product of a polyhalogenated anhydride, ma-
leic anhydride and alkylene glycols.
1,2-benzenediamine, 4-ethoxy, sulfate (1:1).
G Polymer of fatty acids with a substituted alkanoic acid,
carbomonocyclic acids, polyols and a
carbomonocyclic anhydride.
G Polyester from a carbomonocyclic anhydride and sub-
stituted alkanediols.
Polymer of acrylic acid, butyl acrylate, 2-hydroxy ethyl
acrylate, methyl acrylate, and 2-ethylhexyl acrylate.
G Organo zinc salt.
G Polymer of aliphatic polyols, aliphatic and aromatic
tricarboxylic acids.
G Polymer of styrene, methacrylate ester, acrylic ester,
and acrylic acid.
2,2-bis[4-(4-aminophenoxy)phenyl] hexafluoro-
propane.
G Substituted naphthalenylazo naphthalenedisulfonic
acid salt.
G Tetra(substituted sulfonic acid) derivative of transition
metal-acrylcyanine complex.
G Hydrocarbon complex with platinum halide.
G Asphalt styrenated resin.
G Vinylic copolymer.
G Organophosphorus compound.
G Organosulfur compound.
G N-substituted-N-mixed alkyloxy-propylmaleamic acid
derivatives.
G N-substituted-N-mixed alkyloxy-propylmaleamic acid
derivatives.
G N-substituted-N-mixed alkyloxy-propylmaleamic acid
derivatives.
G N-substituted-N-mixed alkyloxy-propylmaleamic acid
derivatives.
47 FR
52220
(11/19/82)
Do
Do
Do
Do
Do
47 FR
53782
(11/29/82)
Do
Do
47 FR
55422
(12/9/82)
Do
47 FR
57332
(12/23/82)
Do
Do
Do
Do
Do
Do
Do
Do
Do
Do
REGULATION PENDING DEVELOPMENT OF INFORMA-
TION ... SECTION 5fe)
When information on a substance is insufficient to per-
mit a reasoned evaluation and either the manufacture,
processing, distribution in commerce, use or disposal
may present an unreasonable risk of injury to health
andior the environment or the substance may be pro-
duced in large quantitites and may present significant
or substantial human exposure to it, the Administrator
may issue a proposed order, to take effect on the expi-
ration of the notification period applicable to the manu-
facturing or processing of such substance to prohibit or
limit the manufacture, processing, distribution in com-
merce, use, or disposal of such substance or to prohibit
or limit any combination of such activities.
EPA Issues PMN 5(e) Consent Orders on Eight
Chemicals
Since January, 1983, EPA has issued four consent or-
ders under section 5(e) which cover eight chemicals.
Only five orders have been issued in the past 3 1/2
years. EPA expects six to ten section 5(e) orders in the
next two months. Within this total of 5(e) orders a fur-
ther shift in emphasis should be noted. This change is
increased use of a section 5(e) Consent Order to require
protective measures where in previous years manufac-
turers only stated in the PMN submission that special
engineering controls or protective equipment that elim-
inated exposure would be recommended. Use of a
Consent Order allows those measures to be enforced.
Below are the 5(e) orders issued since January 1983:
CONSENT
ORDER
NO.
PMN NO.
CHEMICAL IDENTIFICATION
(0»QENERIC)
FR
CITATION
(DO-DITTO)
ORDER DESCRIPTION
6
82-684
G Halogenated hydrocarbon
47 FR 43160
9-30-82
A 5(e) Consent Order was negotiated
establishing use of protective equip-
ment during portions of manufactur-
ing and processing of the chemical.
The Order was issued January 17,
1983.
7

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7
83-23
G Substituted phenol
47 FR 46371
10-18-82
A 5(e) Consent Order of March 9, 1983
requires use of dermal protection for
all of the substances, and positive
pressure, full facepiece air-supplied
respirators for two of the chemicals,
pending information sufficient to as-
sess the risks posed. The chemicals
were referred for follow up review.

83-24
G Substituted pyridine
Do


83-49
G Substituted pyridine
47 FR 49072
10-29-82


83-75
G Sodium 2-substituted
propanoate
47 FR 50338
11-5-82


83-272
G Substituted pyridine
47 FR 57332
12-23-82

8
83-237
G Substituted pyridine
47 FR 53782
11-29-82
On April.4, 1983, a Consent 15(e) Or-
der was signed by the Agency. The
Order requires the use of safety
equipment and processing controls at
manufacturing and processing sites.
9
83-255
	
G Dicarboxylic Acid Monoester
47 FR 54537
12-3-82
On April 18, 1983 a consent 5(e) order
was signed, which requires the use of
protective equipment during process-
ing, application of a label, and written
notice to all workers who may be ex-
posed to the PMN substance. It also
bans domestic manufacture.
REPORTING RULES
SECTION 8(a)
Under section 8(a) EPA may require manufacturers and
processors to submit information on named chemicals
of the following types: production, use, occupational
exposure and environmental release.
Summary Of 8(a) Preliminary Aseesment Information
Amendment*
•	Final amendment permitting all chemicals and mix-
tures designated by the Interagency Testing Commit-
tee (ITC) for testing consideration to be made subject
to the rule without separate proposal and comment-
Published May 11. 1983 (48 FR 21294).
•	Final amendment requiring reporting by manufactur-
ers of remaining chemicals designated by the ITC on
its Sixth through ninth reports—Published May 19,
1983 (48 FR 22694).
•	Proposed amendment requiring reporting on chemi-
cals recommended by the ITC in its Eleventh Report-
Published May 19,1983 (48 FR 22697).
•	Amendment (automatic final) requiring reporting on
chemicals designated by the ITC in its Twelfth Re-
port—to be published in June, 1983.
• Rule Related Notice announcing the Agency's intent
to release aggregate statistics from information sub-
mitted under the section 8(a) Preliminary Assessment
Information Rule and the section 8(a) Asbestos Rule—
to be published in June, 19B3.
EPA Proposes Reporting of Information on Chlorinated
Ter phenyl
On April 29, 1983, EPA published a rule (48 FR 19419),
under section 8(a) that would require manufacturers or
importers to report to EPA certain information on any
existing or proposed production of chlorinated
terphenyl. Persons who want to comment on this pro-
posal should submit written comments no later than
June 28, 1983, that bear the document number
OPTS-82007. they should be sent to the TSCA Publica-
tion Information Officer, EPA, TS-793, Rm. E-108, Wash-
ington DC 20460.
The Interagency Testing Committee (ITC) designated
the category of polychlorinated terphenyls for testing
consideration in April 1978 (43 FR 16684). Chlorinated
terphenyl is a member of this category and is the only
member of this category on the TSCA Chemical Sub-
stance Inventory. Other members of the category are
subject to Premanufacture Notification under section 5
of TSCA.
The ITC recommended that polychlorinated terphenyls
be tested for carcinogenicity, mutagenicity,
8

-------
teratogenicity, other chronic health effects, and for en-
vironmental effects. Because domestic production and
importation of chlorinated terphenyl apparently have
ceased, EPA concluded that the section 4 testing recom-
mended by the ITC is not warranted, (see EPA's re-
sponse to the ITC 46 FR 54482), and that a section 8(a)
rule can alert the Agency of any resumption of manu-
facture of importation. If EPA is notified of chlorinated
terphenyl manufacture or import, the Agency will re-
consider the need for action to require testing under
section 4 of TSCA or for control of the reported activity.
SIGNIFICANT NEW USE ... SECTION 9(a)(2)
Under section 5(a)(2) EPA determines when certain
uses of chemical substances are significant new users.
A determination is made by a significant new use rule
(SNUR) promulgated after considering all relevant fac-
tors. The factors include the projected volume of manu-
facturing and processing of the substance, the extent to
which the substance's new use changes the type and
form of exposure to humans or the environment, the
extent to which the substance's use increases the mag-
nitude and duration of exposure to humans of the envi-
ronment, and the anticipated manner and methods of
manufacturing, processing, distributing in commerce
an disposal of the substance. Under section 5(a)(1)(B),
persons must notify EPA at least 90 days before manu-
facturing, processing or importing a chemical sub-
stance for a significant new use as determined by EPA.
In addition, persons who intend to export, for any pur-
pose, a substance that is subject to a proposed SNUR
must notify EPA under section 12(b).
EPA Proposed Chlorinated Naphthalene* SNUR
EPA is proposing a Significant New Use Rule (SNUR)
under TSCA section 5(a)(2) for a category of existing
chemicals known as chlorinated napthalenes. Under
this proposed SNUR, any domestic manufacture of
chlorinated napthalenes and any import over 100,000
pounds a year are considered "significant new uses"
subject to SNUR reporting. The proposed rule was pub-
lished on Friday May 6, 1983, (48 FR 20668). Persons
who want to comment on this proposal should submit
written comments no later than July 5, 1983, that bear
the document number OPTS 60502. They should be sent
to the TSCA Publication Information Officer, EPA,
TS-793, Rm. E-108, Washington DC 20460.
EPA has serious health and environmental concerns
about chlorinated napthalenes. The Agency is primarily
concerned about the potential for oncogenicity in hu-
man exposed to the substances. In addition, EPA is con-
cerned about chlorinated napththalenes' potential for
other health effects, as well as potential ecological haz-
ar 8 re8u'ting from release of the substances.
~ 9J8Lth# ,nt#rafl«ncy Testing Committee (ITC) desig-
th* "tegory of substances known as chlorinated
napthalenes for priority consideration for a test rule un-
der section 4 of TSCA. The ITC recommended that the
following tests be conducted for chlorinated
napthalenes: mutagenicity, teratogenicity, long-term
carcinogenicity, environmental effects tests, and chron-
ic studies to evaluate the other effects of prolonged ex-
posure. However, because the use of chlorinated
napthalenes had declined sharply (34,000 pounds
imported in 1981) and because domestic menufacture
of the substances had ceased, EPA announced that it
would not propose a section 4 test rule, instead, the
Agency requested comments on regulatory
alternatives.
After evaluating the comments, EPA decided to propose
a SNUR so that the Agency can assess risk resulting
from a significant change or increase in human or envi-
ronmental exposure to chlorinated napthalenes before
the exposure occurs.
HEALTH AND SAFETY RULE ... SECTION 8(d)
Section 8(d) authorizes EPA to promulgate rules on
specifically listed chemicals and categories of chemi-
cals that would require manufacturers and processors
to submit lists and copies of health and safety studies
that they have conducted or were initiated by them.
EPA Adds Substances To 8(d) List
Eleven chemicals and three categories of chemicals
have been added to the list of substances and mixtures
for which lists and copies of unpublished health and
safety studies must be submitted to EPA under the sec-
tion 8(d) health and safety data rule. The substances
were named in a March 30, 1983 Federal Register notice
(48 FR 13178).
On September 2, 1982, EPA published (47 FR 38780) a fi-
nal rule requiring chemical manufacturers and
processors to provide the Agency with unpublished
health and safety information on specific chemicals. In
that notice EPA listed chemicals and categories that be-
came subject to the rule's requirements. EPA will use
the studies to aid its investigation of the risks posed by
chemicals and to help it determine whether to require
industry to test chemicals under section 4.
The following chemical and categories of chemicals
designated mixtures are subject to the section 8(d) rule.
Benzyl butyl phthalate, 85-68-7
Biphenyl, 92-52-4
Butyl gylcolyl butyl phthalate, 85-70-1
Chlorendic acid, 115-28-6
4-Chlorobenzotrifluoride, 98-56-6
2-Chlorotoluene, 95-49-8
Diethylenetriamine, 111-40-0
Ethyltoluenes
This category consists of ethyltoluene (mixed iso-
mers) and the ortho-, meta- and para-isomers.
Ethyltoluene (mixed isomers), 25550-14-5
o-Ethyltoluene, 611-14-3
m-Ethyltoluene, 620-14-4
p-Ethyltoluene, 622-96-8
Fluoroalkenes
This category is defined as fluoroaikenea of the gen-
eral formula:
CnH|n—*Fi
where n equals 2 or 3 and x equal 1 to 6,
As of March 30, 1983, this category includes, but Is
not limited, to the following four fluoroalkenes
and any category members reported as confiden-
tial for the TSCA Inventory. Any subatences fitting
the category definition Added to the TSCA Inven-
tory after March 30, 1983, are also subject to this
subpart.
9

-------
Tetrafluoroethene, 116-14-3
Trifluoroethene, 359-11-5
Hexafluoropropene, 116-15-4
Trifluoromethylethene, 677-21-4
Formamide 75-12-7
Hexachloroethane 67-72-1
Phenylenediamines
This category is defined as all nitrogen-unsubstituted
phenylenediamines and their salts with zero to
two substituents on the ring selected from the
same or different members of the group of halo,
nitro, hyroxy, hydroxy-lower alkoxy, lower-alkyl,
and lower alkoxy. For this purpose, the term
"lower" is defined as a group containing between
one and four carbons.
As of March 30, 983, this category includes, but is not
limited to, the following phenylenediamines and
any category members reported as confidential
for the TSCA Inventory. Any substances fitting the
category definition added to the TSCA Inventory
after March 30, 1983, are also subject to this
subpart.
O-Diaminobenzene, 95-54-5
2,5-Diaminotoluene, 95-70-5
1.3-Diamino-4-methylbenzene,	95-80-7
O-Phenylenediamine, 4-chloro- 95-83-0
O-Phenylenediamine, 4-nitro- 99-56-9
m-Diaminobenzene 108-45-2
3,5-Diaminotoluene 108-71-4
2.4-Diaminophenol	dihydrochloride 137-09-7
1,2-Diamino-4-methylbenzene 496-72-0
m-Phenylenediammonium dichloride 541-69-5
m-Phenylenediamine, sulfate (1:1) 541-70-8
m-Phenylenediamine, 4-methoxy-dihydrochloride
614-94-8
m-Phenylenediamine, 4-methoxy-616-05-4
1,2-Phenylenediamine dihydrochloride 615-28-1
1.4-Benzenediamine,	2-methyl-dihydrochloride,
615-45-2
p-Phenylenediamine, 2-chloro-, dihydrochloride,
615-46-3
2.5-Diaminotoluene	sulfate, 615-50-9
p-Phenylenediamine dihydrochloride, 625-18-0
2.6-Diamino-1	-methylbenzene, 823-40-5
o-Phenylenediamine, 4-ethoxy- 1197-37-1
1,2-Diamino-3-methylbenzene 2687-25-4
o-Phenylenediamine, 4-butyl-3663-23-8
m-Phenylenediamine, 5-nitro-5042-55-7
m-Phenylenediamine, 4-nitro-5131-58-8
m-Phenylenediamine, 4-chloro- 5131—60—2
p-Diaminoanisole, 5307-02-8
p-Phenylenediamine, 2-nitro- 5307-14-2
m-Phenylenediamine, 2-nitro- 6219-67-6
p-Phenylenediamine, 2-chloro-, sulfate, 6219-71-2
o-Phenylenediamine, 4-nitro-, sulfate, 6219-77-8
1,4-Benzenediamine, 2-methyl-, sulfate, 6369-59-1
4,6-Diamino-o-cresol, 15872-73-8
p-Phenylenediamine sulfate, 16?45-77-5
p-Phenylenediamine, 2-nitro-, dihydrochloride,
18266-652-9
p-Phenylenedi8mine, 2,5-dichloro- 20103-09-7
Diaminotoluene, 25376-45-8
2,4-Diaminoanisole sulfate, 39156-41-7
1,2-Benzenediamine, 5-chloro-3-nitro- 42389-30-0
1,4-Benzenediamine, ethanedioate (1:1), 62654-17-5
4-6-Diamino-2-methylphenol, hydrochloride,
65879-44-9
Ethanol, 2-(2,4-diaminophenoxy)-, dihydrochloride,
66522-95-5
1,3-Benzenediamine, 4-ethoxy-, dihydrochloride,
67801-06-3
1,3-Benzenediamine, 4-ethoxy-, sulfate (1:1),
68015-98-5
m-Phenylenediamine, 4-chloro-, sulfate, 68239-80-5
1,2-Benzenediamine, 4-nitro-, sulfate (1:1),
68239-82-7
1-4-Benzenediamine, 2-nitro-, sulfate (1:1),
68239-83-8
1.2-Benzenediamine,	4-chloro-, sulfate (1:1),
68459-98-3
1.3-Benzenediamine,	ar-ethyl-ar-methyl, 69866-84-7
1,2,4-Trimethylbenzene, 95-63-6
Tris (2-chloroethyl) phosphite, 140-08-9
SUBSTANTIAL RISK ... SECTION 8 (•)
Under section 8(e) persons who obtain new information
which reasonably supports the conclusion that a sub-
stance presents substantial risk of injury to human
health or the environment must notify EPA within 15
days. These notices are then reviewed by OTS and an
initial evaluation is prepared containing, if appropriate,
followup questions to the submitter, referrals to other
agencies, and recommended OTSIEPA followup actions.
The 8(e) notices represent a company's first review of a
situation and a judgment in compliance with the statute
to submit a notice within IS days of obtaining the infor-
mation. EPA publishes its evaluations of these notices
to make this section 8(el information widely available
and understandable to a broad public. The submissions
and the initial evaluations are located in the OPTS Pub-
lic Reading Room, first floor. East Tower, Waterside
Mall, 401 M Street, SW, Washington, D.C.
Parsons wishing to obtain a oopypf	-	
may write: Ms. Jerri Green, EPA (A-101), Washington,
D.C. 20460. There is no charge for duplicating the first
49 pages, but at page 50 of a request for duplication
there is a $10.00 fee and a 200 charge for each addition-
al page (e.g., 51 pages cost $10.20).
Single copies of the 8(e) initial evaluation (not the full
submission) are available from the TSCA Assistance
Office.
Recent Selection 8(e) Notices of Substantial Risk
Log No. 8EHQ-	[CAS NO]
1282-0467
Ethyl Aery late	140-88-5
Summarized preliminary results from an NTP
carcinogenesis bioassay (by gavage).
0183-0468
Carbon Black Feedstock	64742-10-5
Final results of several in vitro mutagenicity and acute
in vivo toxicity studies.
0283-0469S
Nitrosamine and non-nitrosamine	None
Metalworking (Cutting) Fluids)
Summarized results from a lifetime skin-painting study.
0283-0470
4,4-Dimethyl-1,3 oxazolidine	51200-87-4
Final results of two in vitro genotoxicity screening
assays.
10

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0283-0471S
Klarus 1717 Metalworking (cutting) Fluid None
Bis (2-chlorooctyl) disulfide	70776-26-0
Final results of in vitro mutagenicity and acute in vivo
toxicity (Including sensitization) studies and reported
cases of contact dermatitis in workers.
0283-0472S
Heavy Catalytic	Reformed Naptha
and/or	64741-68-0
Kerosene	8008-20-6
Summary of preliminary	results from lifetime skin-
painting study.
0383-0473
Vermiculite	1318-00-9
Tremolite	14567-73-8
Preliminary results from an ongoing epidemiology
study.
0383-0474
Acetaldehyde	76-07-0
Summarized preliminary results of a lifetime inhala-
tion study.
0483-047B
2-Butoxyethanol	111-76-2
Summarized interim results of an ongoing teratology
study.
SUPPORT ACTIVITY
EPA To Make Public A Status Report On Existing
Ch*mioala
The OTS is now issuing a quarterly report, and is mak-
ing it available, on the status of various existing chemi-
cals that are being reviewed for possible action under
TSCA. OTS also plans to inform the public about up-
coming Chemical Hazard Information Profiles (CHIPs)
so that there can be more public input into the TSCA ex-
isting chemicals program. A CHIP itself is a brief sum-
mary of readily available information concerning the
health and environmental effects and potential expo-
sure of a chemical. When new CHIPs are produced the
Chemicals-in-Progress Bulletin will inform the public,
(see related story "EPA Requests Information For
CHIPs")
Both the January-March 1983 quarterly report on the
status of existing chemicals and a list of existing CHIPs
are available through the TAO. The TAO also has two
previously offered papers that explain the TSCA ex-
iting chemicals program. In early 1982, EPA produced
Priorities for OTS Operations" and in November 1982
issued a supplement "Existing Chemicals Program"
which describes the process for evaluation of existing
chemicals.
EPA Raquaats Information For CHIPs
OTS is requesting information from the public on chem-
icals chosen for Chemical Hazard Information Profiles
(CHIPS). Because the literature search for a CHIP is gen-
erally limited to automated data bases and reference
works, OTS encouragas interested parties to submit un-
published, recently published and other hard-to-obtain
studies on the chemical(s) of interest. Relevant studies
include those which pertain to health effects, environ-
mental effects, commercial production and uses, ex-
posed populations, environmental levels, and any other
information relevant to an assessment of the chemical's
impact on human health or the environment. OTS is
also interested in any current testing or assessment ac-
tivities being conducted by other organizations.
When a chemical is selected for CHIP preparation, the
TSCA Assistance Office (TAO) will notify by letter the
organizations and individuals on a mailing list, now be-
ing compiled. To be most helpful, information on chem-
icals chosen for CHIPs should be received within 6
weeks of the TAO letter. Persons who want to be includ-
ed on the CHIP mailing list should call the Toll Free
number at: 800-424-9065 (in the Washington, D.C. area
please call 554-1404). Written request should be sent to
the TSCA Assistance Office (TS-799), EPA, 401 M St.
S.W. Washington, D.C. 20460.
When naw CHIP selections are produced they will be
listed in the Chemicals-in-Progress Bulletin.
CHIPS recently started
dimethyl methyl phosphonate	(756-79-6)
proprionitrile	(107-12-0)
ziram	(137-30-4)
All responses with information on these CHIP
chemicals should be sent to:
Document Control Officer,
Management Support Division (TS-793),
Office of Toxic Substances,
401 M Street, S.W.,
Washington, D.C. 20460,
ATTN: T. O'Bryan
To be considered in the development of these CHIPs, in-
formation should be received by June 30, 1983.
All information submitted in response to the solicita-
tions will be placed in a public file and made available
for public inspection unless the submitter asserts a
claim of confidentiality in accordance with the provi-
sions of section 14 of TSCA. EPA will handle all
confidentiality claims in accordance with its procedures
governing the confidentially of business information
(40 CFR Part 2, Subpart B). Persons may inspect non-
confidential submissions when in Washington, D.C. at
EPA (401 M St. S.W., Room E-107 from 8:00 a.m. to
4:00 p.m. Monday-Friday. OTS encourages comment
on the accuracy and thoroughness of information pre-
sented in the CHIP in an effort to broaden the distribu-
tion of completed CHIPs.
Recently completed CHIPS
[CA8 NO]
iso-Butanol
78-83-1
p-Chlorobeniotrichloride
5216-25-1
C.I. Disperse Yellow 3
2832-40-8
D & C Red No. 9
6160-02-1
High Explosive
CBI
Melamine
108-78-1
n-Propanol
71-23-8
Pentachloroethane
76-0107
11

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EPA Publishes New Volume of Section 8(e) Reports
EPA has just published a third volume of preliminary
evaluations of initial section 8(e) substantial risk no-
tices. The volume covers the February 1, 1980, to De-
cember 31, 1982 period.
All three volumes contain status reports prepared by
the Office of Toxic Substances (OTS) for initial section
8(e) submissions received by EPA from chemical manu-
facturers, processors and distributors. EPA publishes
the volumes of status reports to make the reported in-
formation more accessible. Specific examples of sub-
mitted information and EPA's evaluation of it are in-
cluded in these reports. OTS believes that persons
subject to section 8(e) will be better able to understand
the types of information that should be submitted by
referring to these volumes.
A limited supply of volume 3 is available through the
TSCA Assistance Office (toll-free: 800-424-9065 or in
Washington, D.C.: 554-1404) or write to: TSCA Assist-
ance Office (TS-799), U.S. Environmental Protection
Agency, 401 M St., S.W., Washington, D.C. 20460. Once
this supply is exhausted copies will be available
through the National Technical Information Service
(NTIS).
EPA's supply of the first two volumes in the series is ex-
hausted, but may be purchased from NTIS at 5285 Port
Royal Rd., Springfield, VA 22161. The NTIS order desk
number is (703) 487-4650. The NTIS numbers for the
first two volumes are PB 80-221609 and PB 81-145732.
Clay Named Acting Assistant Administrator for OPTS
Don R. Clay, a career civil servant, has been named Act-
ing Assistant Administrator for Pesticides and Toxic Sub-
stances. He replaces Dr. John A. Todhunter, who re-
signed on March 25, 1983.
Clay, from August 1981, until named to his new assign-
ment, was Director of the Office of Toxic Substances.
Prior to that he managed the engineering sciences pro-
gram of the U.S. Consumer Product Safety Commis-
sion. From 1972 to 1974 he was Deputy Assistant Com-
missioner for Planning and Evaluation at the U.S. Food
and Drug Administration.
Marcia Williams has been named acting director of the
Office of Toxic Substances. Ms. Williams served as dep-
uty director to Mr. Clay since February 1982 and was
formerly with the Office of Pesticides Programs.
TSCA Report to Congress is Available
The TSCA report to Congress for fiscal year 1982 is now
available. The report summarizes progress made by
EPA in implementing the Act during the fiscal year,
which ended on September 30, 1982. After the limited
supply is exhausted, the report may be purchased from
the National Technical Information Service (NTIS).
Industry Assistance Office Named Changed To TSCA
Assistance Office
The Industry Assistance Office's name has officially
changed to the TSCA Assistance Office (TAO). The new
office name reflects broadened responsibilities of the
office to provide assistance not only to the regulated
community but also to other interested citizens as well
as the international community interested in the imple-
mentation activities under TSCA.
New Asbestos-in-Buildlngs Guidance Document
Available
The Office of Toxic Substances recently published a
new document called "Guidance For Controlling Friable
Asbestos-Containing Materials in Buildings." The pur-
pose of the report is to supplement previous EPA guid-
ance by emphasizing recent experience and new infor-
mation on asbestos abatement and control. The
guidance may be helpful to school officials and building
owners who are considering 1 rripi¥m#fwngrW«H'#«tOs
control program. The 154-page document wilt also be
helpful to building owners who must establish priorities
for asbestos abatement and control. The TSCA
Assistance Office is now taking orders for the report.
Because of the expected demand for the book, EPA will
limit the number of copies sent to any one location. The
report is also available from EPA regional offices. When
the supply is exhausted, the report will be available for
purchase through the National Technical Information
Service.
TSCA Assistance Office (TS-799)	Official Business
Office of Pesticides & Toxic Substances	Penalty for Private Use
U.S.E.P.A.	$30°
Washington, D.C. 20460
First Class Mail
Postage and Fees Paid
EPA
Permit No. G-36
THE TSCA CHEMICALS-IN-PROGESS BULLETIN

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