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VOL. 7 No. 4
INSIDE
October 1986
What's Happening in OTS—by Charles R. Elkins
TSCA HOT LINE NO LONGER TOLL FREE; OTHER SERVICES REMAIN SAME
EPA REEVALUATING ASBESTOS-in-SCHOOL PROGRAM
ITC MAY DESIGNATE HEXAMETHYLENEDIAMINE FOR TESTING
EPA PROPOSES HEALTH EFFECTS TESTING FOR DGBE AND DGBA
EPA RULES ON TETRACHLOROBENZENES ENVIRONMENTAL TESTING
EPA PROPOSES TEST RULE FOR VINYIDENE CHLORIDE
EPA PROPOSES HEALTH AND SAFETY REPORTING FOR 107 SUBSTANCES
TEST RULING ON ANILINE CATEGORY DUE SHORTLY
SNURs
EPA Proposes Rule for PMN Chemical
EPA Proposes Combined SNUR and 8(a) Rule for 11-Aminoundecanoic Acid
PETITIONS
EPA Responds To 22 PCB Exemption Petitions
EPA Denies Petition On Mesityl Oxide
FOR YOUR INFORMATION
New Data Available on 8 Chemicals
Now Available: New Chemical Review Process Manual
OTS Distributing Two New CHIPs
Seven New FYls Available
OTS Receives 13 Substantial Risk Notices
EPA Ends Non-CBI TSCA Inventory Searches
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5
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7
This news bulletin is intended to inform all persons concerned
with the Toxic Substances Control Act (TSCA) about recent de-
velopments and near-term plans. For further information or to
request copies of documents mentioned, write the TSCA Assist-
ance Office (TAO), (TS—799) EPA, Washington, D.C. 20460, or
call (202) 554-1404.

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What's Happening in OTS—Charles L. Elkins
This is the first chance since my appointment as Director of the Office of Toxic Substances to com-
municate will all of you, the more than 9,000 readers of this Bulletin. I helped create the Office of
Toxic Substances back in the early 1970s, and although I have worked for many of the Agency's
programs since, I have always had a special interest in the Toxic Substances Control Act. Therefore
I am particularly happy to have the opportunity at this stage in my career to lead EPA's activities in
this area as Director of OTS. I look forward to meeting and working with many of you in the months
ahead.
My appointment as Director happens to coincide with the 10th Anniversary of the passage of the
Toxic Substances Control Act (TSCA). This anniversary, October 11, 1986, is a good time for all of
us to reflect on the past 10 years and the change that has taken place in the way society thinks
about toxic chemicals. We see these changes in the chemical industry, in government agencies
such as EPA, and in the general public. While much progress has been made in identifying and
controlling the risks of toxic substances, many challenges lie ahead as we enter TSCA's second
decade.
As we in EPA reflect on where we have been in the last 10 years and our direction over the next 10, I invite your observations and sugges-
tions concerning our mutual past experiences and future opportunities. Feel free to write to me in care of the Editor, Joe Boyle (TS-799). I
would also welcome your suggestions about what you would like to see in future editions of this Bulletin.
As has been the custom, I plan to take the opportunity afforded by this bulletin to alert you to activities which I think will be of interest to you
on a bi-monthly basis. In this issue I want to alert you to an important new proposal we are making under section 8(a) of TSCA, which we call
CAIR (Comprehensive Assessment Information Rule).
CAIR is a "model" information gathering rule that will simplify reporting for the industry, streamline the information gathering process for EPA
and guard against duplicative reporting. That's a pretty tall order, but we think the proposed rule will meet these goals
Here is the way it will work. CAIR contains a comprehensive list of questions that can be thought of as a "menu" from which EPA selects
questions. When EPA needs information on a particular chemical, we would ask only those questions that will provide the needed informa-
tion on that chemical—all other questions may be ignored. EPA would then propose a specific rule for that chemical, indicating the identity of
the chemical, the questions selected from the CAIR menu, the reporting period and who must report. Comments would be gathered on
everything, except the wording of the questions chosen from CAIR because the wording of those questions would have already been subject
to comment in the CAIR rulemaking. EPA would then finalize the chemical specific rule based upon the record of that proceeding.
How will this simplify reporting for industry? It will standardize the questions that will be used to obtain needed information. Once company
officials become familiar with the questions in the CAIR rule, reporting will be quicker and easier because the officials will not have to be-
come familiar with new questions each time reporting is required. The process will be streamlined because amending the rule will be easier
and quicker than a full chemical-by-chemical rulemaking. The rule also will guard against duplicative reporting because the procedures for
implementing the rule are designed to gather all needed information on a particular chemical at one time.
We're going to allow a 90-day comment period on the CAIR proposal. The proposed rule was published in the Federal Register in early Oc-
tober. If you want to comment and need a copy of the proposed rule call or write the TSCA Assistance Office (TAO).
EPA Reevaluating Asbestos-in-School Program
October 14, 1986, ends a 60-day period in which EPA sought
comments from the public on the future direction of the Agency's
program to reduce risks from asbestos in schools. EPA currently
uses guidance and technical assistance, with limited Federal
regulation, to address asbestos risks in schools. EPA is consid-
ering whether to expand its current approach or to place a
greater emphasis on Federal regulation. On August 12, 1986,
EPA sought comment and information on this issue (51 FR
28915). Commenters were asked to consider their preferences
in the context of the limited resources available to administer
current or future Federal programs. After review of the submis-
sions from the public, EPA may propose further regulatory re-
quirements, under section 6(a) of TSCA. Within a year, EPA ex-
pects either to propose additional Federal regulations of publish
reasons why it believes additional regulations are not
necessary.
ITC May Designate Hexamethylenediamlne For Testing
The Interagency Testing Committee (ITC) may designate
hexamethylenediamine (CAS No. 124-09-4) for certain chemical
fate testing in a future report to the EPA Administrator, accord-
ing to an August 7, 1986 notice (51 FR 28431). The ITC re-
quested information on the biodegradation of hexamethylene-
diamine in aerobic ponds and under both aerobic and anaerobic
conditions in disposal wells, in the presence of other waste con-
stituents typical of hexamethyenediamine production.
EPA Proposes Health Effects Testing for DGBE and DGBA
EPA proposed that manufacturers and processors of diethylene
glycol butyl ether (DGBE) CAS No. 112-34-5, and diethylene
glycol butyl ether acetate (DGBA) CAS No. 124-17-4 be re-
quired to perform health effects testing under section 4 of TSCA.
EPA is proposing that DGBE be tested for subchronic toxicity
with particular emphasis on reproductive, hematological, liver
and kidney effects; neurotoxicity/behavioral effects; develop-
mental neurotoxicity; phamacokinetics; and oncogenicity. EPA is
also proposing dermal absorption testing for DGBA, which is
also known as 2-(2-butoxyethoxy)ethylacetate.
This rule proposed on August 4,1986 (51 FR 27880) follows an
Advance Notice of Proposed Rulemaking for these chemicals is-
sued on November 19, 1984 (49 FR 45808). The ITC desig-
nated DGBA for priority consideration in its 13th report (49 FR
55874; December 14, 1983).
2

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EPA Rules on Tetrachlorobenzenes Environmental Testing
EPA decided not to require environmental effects testing for
tetrachlorobenzenes [July 24, 1986 (51 FR 26595)]. EPA con-
sidered requiring environmental effects testing after the Agency
was informed in 1983 that chemicals in the category might be
used as a retrofill agent for PCB-containing electrical
transformers.
Because of this concern, EPA, on January 13, 1984 (49 FR
1760) issued an Advance Notice of Proposed Rulemaking and
asked for comments on the possible need to issue a proposed
rule for one or more of the tetrachlorobenzenes.
After reviewing all the available data, EPA anticipates that any
releases of tetrachlorobenzenes to the environment from use in
PCB-containing transformers will be minimal and not expected
to result in any unreasonable adverse effects to the environ-
ment. Tetrachlorinated benzenes are being used only in
transformers and the use will be temporary and limited. Other
fluids will be used as permanent retrofill agents in transformers.
EPA does not consider that further environmental effects testing
is required at this time for this use and will monitor the produc-
tion levels of the tetrachlorobenzenes through updates of the
TSCA chemical inventory.
In addition to environmental testing, EPA earlier published re-
quirements to conduct reproductive effects and developmental
toxicity testing. These regulations were published on July 8,
1986 (51 FR 24657).
EPA Denies Petition On Mesltyl Oxide
A Chemical Manufacturers Association (CMA) petition asking
EPA to reconsider and withdraw a TSCA Phase 1 test rule for
mesityl oxide (MO) was denied by EPA (August 25, 1986; 51 FR
30217). On December 20, 1985 (50 FR 51857) EPA published a
Phase 1 rule, under section 4 of TSCA, requiring manufacturers
and processors of MO to conduct certain health effects studies
because the Agency found that manufacture, processing and
distribution in commerce of MO may present an unreasonable
risk of injury to health. On April 30, 1986, CMA filed the petition
under section 21 of TSCA for several corporations.
EPA Responds to 22 PCB Exemption Petitions
On August 8, 1986, EPA issued a rule that addressed 22 out-
standing petitions that asked for exemption from the TSCA pro-
hibition against the manufacture, processing and distribution in
commerce of polychlorinated biphenyls (PCBs) (51 FR 28556).
EPA granted 10 individual petitions, granted a class exemption
that included six individual petitions, granted one petition in part,
denied one in part, denied three petitions totally and dismissed
two petitions.
The majority of the exemption petitions were for activities that
were underway prior to the 1979 PCB prohibition in manufactur-
ing and processing. A petitioner whose exemption was granted
will be allowed to manufacture, process or distribute in com-
merce PCBs only for one year. In deciding on whether to grant a
petition, EPA considered the effects of PCBs on health and the
environment and whether the company had made good faith ef-
forts to find a substitute for PCBs in the activity seeking to be
exempted.
EPA Proposes Test Rules for Vinylidene Chloride
On August 12, 1986, EPA issued a proposed rule, under section
4 of TSCA, to require manufacturers and processors of
vinylidene chloride, also known as 1,1-dichloroethylene (CAS
No. 75-35-4) to conduct distribution, excretion and metabolism
(DEM) studies of the chemical (51 FR 28840). EPA also pro-
posed a 2-year inhalation oncogenicity bioassay in mice, to be
undertaken after the DEM data are completed and evaluated.
The chemical was recommended for testing by EPA's Office of
Air Quality Planning and Standards. The chemical had been
considered for regulation as a potentially toxic air pollutant un-
der the Clean Air Act, but a temporary decision was made not to
regulate it (50 FR 32632; August 13, 1985). At that time some
data suggested that 1,1-dichloroethylene might be an oncogen,
but the available information was insufficient to support a deci-
sion to regulate. Now, using TSCA section 4, EPA will obtain
data to assess the oncogenic potential of vinylidene chloride,
which is used most often in the production of polymers.
EPA Proposes Health and Safety Reporting For 107
Substances
EPA is proposing to add 107 chemicals to the list of substances
in TSCA's section 8(d) Health and Safety Data Reporting Rule.
If the proposal becomes final, past, present, and prospective
manufacturers, importers, and processors of the 107 sub-
stances would be required to provide EPA with lists and copies
of unpublished health and safety studies on these chemicals.
EPA will use the information to support a detailed assessment of
the health and environmental risks of these substances. Copies
of the rule proposed on August 1,1986 (51 FR 27562), including
the list of the nominated substances, are available through the
TAO.
The rule is part of a recent effort by OTS to make its unique in-
formation gathering authorities available to other EPA programs
and other agencies. For example, in January, 1986, OTS issued
a final rule requiring industry to submit unpublished health and
safety studies on 33 chemicals of interest to EPA's Office of
Solid Waste (OSW). Over 100 studies have been received and
are now being reviewed by OSW.
in this latest proposed rule chemicals were nominated by sev-
eral EPA offices beside OTS, including the Office of Drinking
Water, the Office of Water Regulations and Standards, and
OSW. in addition Chemicals were nominated by the Consumer
Product Safety Commission.
Two New CHIPs Available
OTS is distributing two new profiles, one on the chemical
hexafluoroisobutylene (CAS No. 382-10-5) and the other is on
the chlorinated styrene category. Both reports are part of the
OTS Chemical Hazard Information Profile (CHIP) series. A
CHIP is a brief summary of readily available information con-
cerning the health and environmental effects and potential expo-
sure to a chemical. CHIP candidates are chosen on the basis of
information indicating a potential for adverse health or environ-
mental effects along with evidence of significant production or
some type of exposure.
Copies of the new CHIPs may be obtained by contacting the
TAO. OTS encourages comments on the accuracy and thor-
oughness of information presented in a CHIP.
3

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New Data Available On 8 Chemicals
EPA recently received new test data submissions on eight chemicals subject to TSCA voluntary industry testing programs [August 1, 1986
(51 FR 27596). The chemicals, their Chemical Abstract Service numbers and studies are:
Antimony oxide
1309-64-4
Sediment (TLC)
Butylbenzyl phthalate
85-68-7
Well water solubility
Chlorotoluene
95-49-8
Analytical data
Cyclohexanone
108-94-1
2-Generation reproductive (rat) (inhalation)
Di-(2-ethylhexyl) terephthalate
6422-86-2
Seed germination (radish, ryegrass and soybeans)


(14-day)
Trichloroethane
71-55-6
Chronic oncogenicity (rat) (inhalation)
Tris-(2-ethylhexyl) trimellitate
3319-31-1
UDS (rat)
Vinylidene fluoride
75-38-7
90-day subchronic (rat) (inhalation)
The data are available for inspection at the OTS Public Reading Room, NE-G-004, 401 M St. SW, Washington, D.C.
Persons interested in obtaining copies of the data listed above may write: EPA, Freedom of Information. Ms. Jeralene Green (A-101) Wash-
ington, D C. 20460. There is no charge for duplicating the first 124 pages, but at page 125 of a request for duplication there is a $25.00 fee
and a 20 cent charge for each additional page (e.g., 126 pages will cost $25.20). Many of the reports listed above are more than 126 pages.
EPA Proposes Rule for PMN Chemical
EPA is propsing a significant new use rule (SNUR) for
benzenamine, 3-chloro-2,6-dinitro-N, N-dipropyl-4-(trifluoro-
methyl) which was the subject of a TSCA premanufacturing
notice (P-86-83) and a section 5(e) consent order issued by
EPA. The Agency believes this substance CAS No. 29091-20-1
may be hazardous to human health and that the uses described
in this proposed rule may result in significant human exposure.
As a result of this SNUR, persons who intend to manufacture,
import or process this substance for a significant new use would
be required to notify EPA at least 90 days before beginning this
activity.
EPA is proposing to designate the following as significant new
uses of CAS No. 29091-20-1:
•	Use other than as a site-limited intermediate in the synthesis
of another organic substance.
•	Any method of disposal associated wit|i the above use other
than by deep-well injection or incineration, each of which meets
all applicable local, State and Federal laws and regulations.
•	Any manner or method of manufacturing, importing or proc-
essing associated with the use described above without estab-
lishing a program whereby any person exposed dermally to the
substance must wear gloves that are determined to be impervi-
ous to the substance; clothing that covers any other exposed
areas of the arms, legs and torso; and chemical safety goggles
or equivalent eye protection. Potentially exposed persons must
be informed of the possible hazards and the EPA required pro-
tective equipment.
For additional information about SNURs and section 5(e) of
TSCA see page 6 of this Bulletin.
Test Ruling on Aniline Category Due Shortly
A target date of October 30,1986 has been set for a decision by
EPA on whether it will use the consent agreement process or a
TSCA section 4 test rule for aniline and seven substituted
alilines (August 11, 1986; 51 FR 28758). All eight substances
are members of the aniline and chloro-, bromo-, and (or)
nitroanilines, which were designated by the ITC for testing (Jan-
uary 3, 1984; 49 FR 108).
EPA Proposes Combined SNUR and 8(a) Rule For Acid
A combined TSCA significant new use rule (SNUR) and section
8(a) rule was proposed on July 22, 1986 (51 FR 26273) for
11-aminoundecanoic acid (11-AA) (CAS No. 2432-99-7).
Results of a carcinogenesis bioassay conducted by the National
Toxicology Program indicate that the substance may cause can-
cer. 11-AA is currently used to manufacture nylon 11 in an en-
closed process that EPA has evaluated and determined to be
protective of human health. Under the significant new use re-
quirements, persons who manufacture, import or process
11-AA for any use other than as an intermediate in the manu-
facture of nylon 11 in an enclosed process would be required to
file a significant new use notice with the Agency. Under the sec-
tion 8(a) provisions, persons who manufacture, import or proc-
ess 11 -AA for use as an intermediate in the manufacture of ny-
lon 11 in an enclosed process would be required to report,
unless that use was ongoing, in the three years ending July 22,
1986, or unless that person qualifies as a small business.
New Chemical Review Process Manual Is Available.
A manual providing an introduction to the new chemical review
process as it takes place in OTS now is available for purchase.
The manual presents the process in terms of component proce-
dures and meetings. A flow diagram of the process is included.
The manual also presents EPA's statutory authority and options
for actions taken under section 5 of TSCA. The manual is being
sold by the U.S. Department of Commerce's National Technical
Information Service (NTIS).
Requestors should ask for the TSCA New Chemical Review
Process Manual (PB86 196565/AS). In paper the manual costs
$9.95 and in microfiche $5.95. There is also an NTIS service
charge. NTIS accepts telephone orders (703) 487-4650 and
American Express, MasterCharge and Visa. Mailed orders
should be sent to: NTIS, 5825 Port Royal Rd., Springfield, VA
22161.
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Section 8(e)... Substantial Risk
Below, and in the next column, is a list of initial section 8(e) no-
tices recently placed in EPA's public file. For an explanation of
section 8(e) and how copies of notices can be acquired see
page 7 of this Bulletin
Log No. 8EHQ-
CAS No.
0786-0608 S
Metal salt of a phosphoric acid ester	Confidential
Final results from an Ames test, an in vitro hamster cell sister
chromatid exchange assay and a 28-day repeated skin ap-
plication study in rats
0786-0609 S
Heterocyclic derivative	Confidential
Preliminary findings of a 4-hour inhalation study in rats
0786-0610
Mineral seal oil	64742-80-9
Final reports on in vitro mutagenicity and ceil transformation
assays
0786-0611 S	75-21-8
Ethylene oxide
Summarized unpublished preliminary findings from a clinical
neurotoxicology study of hospital workers
0786-0612
Diallyl maleate	999-21-3
Preliminary report of dermal sensitization in a worker
0786-0613 S
Heterocyclic thiophosphate	Confidential
Final reports from a variety of in vitro and in vivo genotoxicity
assays
"S" at the end of a Log Number means a sanitized version is
available.
0786-0614 S
Octyltin trichloride and
Dioctyltin dichloride (Mixture)
Final results of a chronic feeding study in rats
3091-25-6
3542-36-7
0786-0615
1,3-Butadiene	106-99-0
Final report of an epidemiology study of workers at a
1,3-butadiene production facility
0786-0616
Copper dimethyldithiocarbamate	137-29-1
Preliminary results of a 4-hour inhalation toxicity study in rats
0786-0617
Ethanol	64-17-5
Butyraldehyde	123-72-8
Report of an emergency incident of environmental contamina-
tion (EIEC)
0886-0618 S
Cadmium oxide	1306-19-0
Cadmium sulfide	1306-23-6
Cadmium sulfate	10124-36-4
Preliminary results of chronic inhalation toxicity studies in rats
0386-0619
0586-0619 Followup Response
Calcium sodium metaphosphate fibers	23209-59-8
Results of a chronic pleural implantation study in rats
0886-0620
Di-n-butyl phthalate and	84-74-3
Dimethyl phthalate	131-11-3
Summarized preliminary results from in vitro mutagenicity and
cell transformation assays
Latest FYI Submissions
In recent weeks EPA received seven FYI (For Your Informa-
tion) submissions. For additional information on FYls see
page 7 of this Bulletin.
Document Control No. FYI	CAS No.
Chemical Names(s)
OTS-0786-0500
N (cyclohexylthio)phthalimide	17796-82-6
Summarized final results from a 2-year dietary chronic toxicity
and carcinogenicity study in rats
OTS-0786-0501
Used Motor Oil	None
Summarized final results from a 30-week carcinogenicity skin
painting study in mice
OTS-0786-0502
Several corrosion inhibitors and pesticides	Unknown
Material Safety Data Sheets, Product Data Sheets and summa-
rized aquatic toxicity and environmental fate data.
OTS-0786-0503
1-Phenoxy-2-propanol;	770-35-4
2-Phenoxy-1-propanol;	4169-04-4
Phenoxypropanol deriviatives Unknown
Summarized final results from a 14-day dermal toxicity study in
rabbits
OTS-0886-O504
11 Material Safety Data Sheets	CBI
AX-0886-0505
25 Lubricant additives	Unknown
Final reports of acute toxicity studies in the sheepshead
minnow
OTS-0886-0506
Pyrazole carboxamide derivative	CBI
Summarized final results from an 14-day oral pilot neurotoxicity
study in dogs
CBI = Confidential Business Information
5

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Below and on the next page are explanations of sections of
TSCA that are cited in this issue of the Bulletin. For addi-
tional information about TSCA's provisions, call (202)
554-1404, or write the TAO.
Section 5 ... MANUFACTUI
Section 5 of TSCA gives EPA authority to quickly review and
control, it necessary, new chemicals to prevent large scale dis-
section 5(a)(1)... Premanufacturing Notices (PMNs)
A person who intends to introduce into commerce a chemical
substance not on the TSCA inventory must notify EPA at least
90 days before beginning manufacture or import.
Section 5(e) Action Pending Development of Information
The Administrator may issue a section 5(e) order to take effect
at the end of the Agency review period following receipt of a
premanufacture notice (PMN) or a significant new use notice.
The order may limit or prohibit manufacture (import), processing,
distribution in commerce, use, or disposal of a chemical sub-
stance. The action can be taken if information available to EPA
is insufficient to permit a reasoned evaluation of the health and
environmental effects of the substance, and if the substance
may present an unreasonable risk to health or the environment.
A section 5(e) order may be issued also if there is insufficient in-
formation and the substance is or will be produced in large
quantities and may result in significant or substantial human ex-
posure, or substantial release to the environment.
A section 5(e) order can be a consent order or a unilateral order.
In a consent order, EPA negotiates the terms of the order with
the company that submitted the notice. The company agrees to
be bound by the order and waives its right to file objections to
the order. This waiver does not affect any other rights that the
company may have under TSCA. The company at a later date
can request a modification of the consent order. In a unilateral
order EPA takes action to restrict or prohibit the manufacture of
use in commerce of the substance without negotiating the terms
of the order with the company that submitted the notice.
AND PROCESSING NOTICES
tribution before a new substance's effects on health or the envi-
ronment are fully determined.
Significant New Use Rules (SNURs) ... Section 5(a)(2)
Under section 5(a)(2) EPA may determine by rule that certain
uses of chemical substances are significant new uses. These
rules are referred to as Significant New Use Rules (SNURs). In
making the determination, the Agency considers the potential
exposure associated with the use, the toxicity associated with
the chemical and whether the use is ongoing at the time the rule
is proposed. Persons subject to a SNUR must notify EPA at
least 90 days before manufacturing, importing, or processing the
chemical substance identified in the SNUR for the defined signif-
icant new use oi uses.
A SNUR may be issued for any TSCA chemical subtance.
SNURs may be written for individual chemicals, for chemical
categories, and for new or existing chemicals. SNURs may be
written in conjunction with a section 5(e) order.
A section 5(e) order can limit or prohibit the use of a chemical
substance that has been the subject of a premanufacture notice
(PMN) or Significant New Use Notice. With regard to new (PMN)
chemicals, once commercial manufacture begins, the chemical
is placed on the TSCA Chemical Substance Inventory. If no
SNUR is issued, the chemical may be used by other manufac-
turers without any restrictions. To establish equity of treatment,
EPA issues SNURs to followup section 5(e) orders, requiring
manufacturers to notify EPA before manufacturing, importing, or
processing the substance for any activities other than those
permitted in the section 5(e) order.
EPA also writes followup SNURs for certain new chemicals
which were not subject to section 5(e) orders. These SNURs ad-
dress concerns which did not trigger a section 5(e) order either
because the concerns arose after the completion of the PMN re-
view or because the uses described in the PMN did not involve
enough exposure to warrant action. Followup SNUBs allow the
Agency to permit safe uses of potentially hazardous new sub-
stances while ensuring that it has the opportunity to review uses
which may lead to significant changes in human or environmen-
tal exposure.
Finally, EPA develops SNURs to support its Existing Chemical
Program risk assessment and risk management activities.
SNURs for existing chemicals are used to monitor significant
new uses of substances on the TSCA Chemical Substance In-
ventory. As with SNURs for new chemicals, existing chemical
SNURs ensure that the Agency will receive information on sig-
nificant new uses of potnetially hazardous substances before
such uses occur. These SNURs also enable EPA to take imme-
diate followup control action (under TSCA section 5(e) or 5(f)) to
limit potential exposure resulting from significant new uses of
existing chemical substances, provided that such followup ac-
tion is necessaary.
6

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Substantial Risk ... Section 8(e)
Under section 8(e), persons who obtain new information that
reasonably supports the conclusion that a substance or mixture
which they manufacture, import, process or distribute presents
substantial risk or injury to human health or the environment,
must notify EPA within 15 working days. These notices are then
reviewed by the Office of Toxic Substances (OTS) and an initial
evaluation (status report) is prepared containing, if appropriate,
followup questions to the submitter, referrals to other agencies,
and recommended OTS/EPA followup actions. The 8(e) notices
represent a company's first review of a situation and a judgment
in compliance with the statute to submit a notice within 15 work-
ing days of obtaining the information.
EPA publishes its status reports to make 8(e) information widely
available and understandable to a broad public. The submis-
sions and status reports are located in the OTS Public Reading
Room, ground floor, Northeast section, Waterside Mall, 401 M
Street, S.W., Washington, D.C.
Persons wishing to obtain a copy of a section 8(e) notice may
write: EPA, Freedom of Information, Ms. Jeralene Green
(A—101), Washington, D.C. 20460. There is no charge for
duplicating the first 124 pages, but at page 125 of a request for
duplication there is a $25.00 fee and a 20 cent charge for each
additional page (e.g., 126 pages will cost $25.20)
Single copies of the section 8(e) status reports (not the full sub-
missions) are available from the TAO.
For Your Information (FYI)
For Your Information (FYI) submissions are submitted voluntar-
ily to the Agency or to the Office of Toxic Substances (OTS) on
chemical toxicity and/or exposure. FYls are submitted by chemi-
cal manufacturers, processors and distributors, trade associa-
tions, labor organizations, Federal, State or local agencies, for-
eign governments, academia, public interest and environmental
groups, as well as by the general public. Microfiche copies of
these submissions are located in the OTS Public Reading
Room, ground floor, Northeast section, Waterside Mall, 401 M
Street, S.W., Washington, D.C. To obtain a copy of an FYI, fol-
low the procedure outlined under section 8(e) Substantial Risk
just above.
Searches of the Non-CBI TSCA Inventory
EPA no longer performs searches, upon request, of the non-
confidential portion of the Toxic Substances Control Act (TSCA)
Chemical Substance Inventory. In the past, companies have re-
quested such searches to determine whether a substance is
listed on the Inventory, to obtain a Chemical Abstracts Service
(CAS) number, or for other reasons.
The same information may be available from any of a number of
sources:
(1)	The 1985 edition of the printed Inventory is available at EPA
Regional Offices many libraries (and some public offices).
The Inventory can be purchased from the Government Print-
ing Office (Document Code S/N 055-000-00254-1). Call
(202) 783-3238 to place an order or write to:
Superintendent of Documents
Government Printing Office
Washington, DC 20402
The 5-volume set costs $161 for persons in the Unied States
or Canada and $201.25 for anyone outside the United States
and Canada.
(2)	The Inventory is also available for sale in computer tape form
from the National Technical Information Service (NTIS). Ask
for PB-86-220878 Call (703) 487-4650, or write to:
National Technical Information Service
5285 Port Royal Road
Springfield, VA 22161
(3)	Searches of the NTIS computer tape of the Inventory are
available from a number of commercial services.
EPA will continue to perform searches of the confidential portion
of the TSCA Chemical Substance Inventory Master File if you
can prove that either:
(1)You	produce the substance; see Instructions for Reporting
for the Partial Updating of the TSCA Chemical Inventory
Data Base, available from EPA by writing to:
OTS Document Control Officer
U.S. Environmental Protection Agency
Office of Toxic Substances (TS-790)
401 M Street, SW
Washington, DC 20460
ATTN: Inventory Update Rule
Telephone: (202) 382-3698 or
(202) 755-4880
or
(2)	you have a bona fide intent to manufacture or import the
substance, pursuant to procedures In 40 CFR 720.25. If you
need help, call the TSCA Assistance Office (TAO),
202-554-1404 and ask them to send the necessary informa-
tion to file a bona fide search request.
7

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NOTICE
As you know, the TSCA Assistance Office has operated a toll-
free information service for the past 10 years for anyone with
questions relating to the Toxic Substances Control Act.
Although we will continue to provide the same information serv-
ice, budgetary constraints made it necessary to discontinue the
toll-free number (800-424-9065) on September 30, 1986. Now
all calls must be placed through 202-554-1404.
TSCA Assistance Office (TS-799)
Office of Pesticide & Toxic Substances
USE.PA.
Washington, D C. 20460.
Official Butlnvss
Penally lor Prlvata UK
$300
Flrat Clan Mail
Poatagt and Frai Paid
EPA
Parmlt No. G-35
THE TSCA CHEMICALS-IN-PROGRESS BULLETIN

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