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Vol. 8 No. 4	September 1987
INSIDE
What's Happening in OTS—By Charles L. Elkins	2
EPA ISSUES BIPHENYL TESTING RULE	6
TESTING OF SOME FLUROALKENES REQUIRED	3
UNION CARBIDE FINED $80,000	2
EPA PROPOSES TESTING FOR DTBP	4
AGENCY SETS TESTING FOR DCBTF	7
ANTHRAQUINONE TESTING AND REPORTING RULE ISSUED	4
EPA SETS HDD AND HDF TESTING AND REPORTING REQUIREMENTS	5
AGENCY ISSUES HYDROQUINONE STANDARDS	7
ITC USING NEW AUTOMATED SCORING SYSTEM	3
EPA PROPOSES AMENDMENTS TO PCB RULE	4
AGENCY DENIES CITIZEN'S PETITION ON PCBs	4
SNUR ISSUED FOR 11-AA	5
FOR YOUR INFORMATION
EPA Report on Regulatory Investigation of Formaldehyde	3
OTS Receives 16 Substantial Risk Notices	6
Trichlorobenzenes and Tetrabromobisphenol A	4
Available: TSCA Guide for Chemical Importers/Exporters	7
Chemicals on Reporting Rules Database	6
12 New FYls Available	7
EPA Files Motion to Withdraw Civil Administration Complaint	2
ITC Brochure Available	3
This news bulletin is intended to inform all persons concerned
with the Toxic Substances Control Act (TSCA) about recent de-
velopments and near-term plans. For further information or to re-
quest copies of documents mentioned, write the TSCA Assist-
ance Office (TAO), (TS-799) EPA, Washington, D.C. 20460, or
call (202) 554-1404.

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What's Happening in OTS—Charles L. Elkins
Suppose you suddenly discovered that a company in a neighbor-
ing town was using a chemical believed to be hazardous to your
health and that some of this chemical is being released to the air.
And suppose some of this same chemical is being released in the
company's waste stream to the river from which your community
draws its drinking water. What would you do? Complain to EPA or
your State? Call the president of the company? Drink bottled wa-
ter? Sell your home and move?
All of these are possible reactions and you might end up doing
one or more of them. As a first step, however, you could do what
the scientists in the Office of Toxic Substances do when con-
fronted with a similar problem—use sophisticated computer mod-
eling systems to predict the potential exposure of people to these
emissions. Specifically, you could apply the Graphical Exposure
Modeling System (GEMS) to the estimated emissions from the
company in order to estimate what the chemical concentrations
in the air and water would be by the time the chemical has moved
to your community.
Many of you may be familiar with GEMS. Over the past seven
years while OTS has been developing, expanding, and refining
the system, the GEMS user community has grown to greater than
230 people. GEMS users can be found in nearly every EPA pro-
gram office, every EPA regional office, six other Federal agen-
cies, 21 States, and two European countries. Its popularity results
from having many capabilities in a single, integrated system
which is easy to use and doesn't require the user to be a com-
puter programmer.
GEMS contains several computerized tools that are useful in as-
sessing exposure of chemical substances released to the en-
vironment. These tools include models to simulate the movement
of chemicals in the atmosphere, lakes and streams, soils and
groundwater aquifers. They also include databases to support
the use of these models, methods for estimating properties of
organic chemicals, statistical analysis programs, and graphics
and mapping packages.
Now back to one part of our earlier example community. Using
GEMS you can generate a map showing the river that receives
the chemical discharge, the location of the discharger and the lo-
cation of downstream drinking water facilities. Next, you can esti-
mate any missing chemical property information that might influ-
ence the behavior of the chem-
ical in the river. The river
database has the environmen-
tal information necessary to
describe the river into which
the chemical is released; and a
component of GEMS automat-
ically builds the needed model
input files in the proper format.
The model is run to estimate
the chemical concentrations in
the river water at the location
of the drinking water intake.
Statistical analysis and graphi-
cal displays of the model data
may be made at this time. After
factoring in any additional removal that might be expected to oc-
cur from drinking water treatment, the data can be compared with
health (toxicity) data to get a better sense of the seriousness of
the problem. I haven t mentioned other exposure pathways which
may be important, such as eating fish or swimming in the river,
but I'm sure you get the idea.
The existence and release of a toxic chemical doesn't necessarily
constitute a serious problem. What is particularly important to the
calculation of the risk to the public is the concentration of the
chemical in proximity to the population. Emission data do not
provide this parameter, but with GEMS one can make an approx-
imation of these concentrations. As OTS prepares to collect
yearly emission data from all major manufactures and users of
toxic chemicals under section 313 of the Superfund Amendments
and Reauthorization Act (SARA), we are seriously considering
making GEMS and a personal computer version of GEMS avail-
able widely to the public in order to lend support to the public's as-
sessment of the significance of these chemical releases to the
environment. Without some way to relate these emissions to ac-
tual exposure, it will be very difficult indeed for the public to dis-
tinguish between really serious toxics problems and less serious
ones. We expect the section 313 Inventory will uncover many ap-
parently serious toxic problems and it will be important that the
public, the States and Federal government be able to distinguish
the really serious problems right away. GEMS may provide part
of the solution.
Access to GEMs is available through EPA and the National Tech-
nical Information Service under an account system. If you are in-
terested in finding out more about GEMS; please write to me in
care of Joe Boyle, Editor, Chemicals-ln-Progress Bulletin, at my
office in Washington.
Union Carbide Fined $80,000
For Risk-Reporting Violations
On July t, 1987, EPA announced that Union Carbide Corp. of
Danbury, Conn., agreed to pay a cash penalty of $80,000 and
perform a corporate-wide environmental audit to settle an admin-
istrative complaint that EPA filed against the company on March
1,1985. In the administrative civil complaint, EPA charged Union
Carbide with delaying over four years the reporting of the results
of a study that showed that diethyl sulfate caused skin cancer in
mice. The $80,000 payment represents the first major penalty
ever collected on a risk-reporting violation under TSCA. The cor-
porate-wide environmental audit that Union Carbide will perform
of its substantial-risk information is the first of this type agreed to
in settlement of a TSCA complaint. Any violations discovered by
the audit will be subject to civil penalties under TSCA. The settle-
ment agreement also incorporates for the first time in an enforce-
ment action an alternative dispute resolution mechanism for re-
solving technical questions. This mechanism is a tool EPA is now
using to resolve disputes.
Lonza Inc.
On July 10, 1987, EPA filed a motion to withdraw a civil admin-
istrative complaint that alleged Lonza Inc. had violated section
8(d) of TSCA, by failing to submit to EPA a short-term air-monitor-
ing study. Section 8(d) of TSCA requires chemical companies to
submit to EPA copies of unpublished health and safety studies on
specific chemicals listed by an EPA rule. The rule requires the re-
porting of workplace monitoring studies, but only when the results
"have been aggregated and analyzed to measure the exposure
of humans or the environment to a chemical substance or mix-
ture."
Lonza's case involves a one-time, one-site atmospheric con-
centration sampling which, according to informal EPA guidance,
is not the type of test data intended to be required by the section
8(d) rule. In addition to dropping the civil complaint against Lonza
Inc., EPA intends to promulgate amendments to the section 8(d)
model health and safety data reporting rule to describe more pre-
cisely what types of monitoring studies must be submitted.
2

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EPA Reports on Its Regulatory Investigation of
Formaldehyde
The Agency's regulatory investigation of urea-formaldehyde
pressed wood products continues its progress as OTS prepares
for an EPA options selection meeting presently targeted for the
spring of 1988. The pressed wood products under investigation
include particleboard, hardwood plywood and medium density fi-
berboard that contain urea-formaldehyde (UF) resin which func-
tions as a wood adhesive. Since beginning the investigation in
May 1984, EPA has reported semi-annually in the Chemicals-in-
Progress Bulletin on the progress of the investigation. This is its
sixth report.
UF pressed wood is widely used as building materials for con-
structing manufactured (mobile) and some conventional homes.
It is also used as industrial board for manufacturing furniture and
cabinetry. Both uses are recognized as important sources of for-
maldehyde and contribute to the higher than normal ambient lev-
els of the chemical sometimes encountered in new or recently re-
modeled indoor environments. With time, high initial levels in
homes decay to lower levels as free formaldehyde emissions
from these boards decline. At the options selection meeting, EPA
decisionmakers will assess the need for, and potential nature of,
additional Federal regulations that address formaldehyde emis-
sions from these products.
Since its last report, EPA has completed and publicly released its
1987 formaldehyde risk assessment. The assessment document
was prepared by Agency scientific staff in consultation with EPA's
Science Advisory Board, an independent panel comprised of sci-
entific experts from outside the Agency. Prepared to serve the
needs of the present OTS investigation, the risk assessment will
also be used by other EPA programs that are concerned with for-
maldehyde exposure from other sources. These programs are
administered by EPA's Office of Air and Radiation and the Office
of Pesticide Programs.
EPA's assessment looked at both the acute and chronic health
effects of low-level exposure to the chemical. In terms of acute
effects (eye, nose and throat irritation, headaches, nausea and a
variety of asthma-like symptoms), it found that people will re-
spond at different levels within the range of 0.1 to 1.1 parts per
million. With respect to chronic effects, the assessment re-
affirmed an earlier classification of formaldehyde as a "Group B1
Probable Human Carcinogen," a classification derived from eval-
uating the scientific evidence in accordance with EPA risk as-
sessment guidelines. The assessment reports cancer risk esti-
mates (including both the "upper bound" and maximum
likelihood" estimates) for several exposure conditions. A sum-
mary of EPA's formaldehyde risk assessme.it is available from
the TSCA Assistance Office.
EPA Requires Testing of Some Fluroalkenes
On June 6, 1987, EPA issued a TSCA section 4 rule requiring
testing for certain health effects for some fluoroalkenes (52 FR
21516). At the same time the Agency withdrew its proposed re-
productive effects testing for vinylidene fluoride.
The fluoroalkenes covered by this rule are:
vinyl fluoride	75-02-3
vinylidene fluoride	75-36-7
hexafluoropropene	116-15-4
tetrafluoroethene	116-14—3
In its seventh report the Interagency Testing Committee desig-
nated the chemical category fluoroalkenes for priority testing con-
sideration by EPA [November 25, 1980 (45 FR 78432)]. Since
then EPA has taken various actions pertaining to fluoroalkenes.
ITC Using New Automated Scoring System
In 1986, the Interagency Testing Committee (ITC) developed
new approaches for the evaluation of several thousand chemi-
cals. This automated chemical scoring system is being used to
govern the process for selecting chemicals to be reviewed in de-
tail by the ITC. Following its detailed review of a chemical, the ITC
may recommend the chemical to EPA for priority consideration
for testing under section 4 of TSCA.
Between 1977 and 1983 the ITC held five "scoring exercises" to
select existing chemicals for the committee to review in detail.
Those exercises focused on chemicals of regulatory concern,
high production chemicals and chemicals recommended by other
organizations.
The ITC is made up of appointed members from eight Federal
agencies as specified in TSCA. Representatives from seven ad-
ditional Federal agencies serve in a liaison capacity.
In 1986, during the ITC's sixth chemical scoring exercise, new
ways of scoring were developed and implemented. Approx-
imately 20,000 discrete organic chemicals that are on the TSCA
Chemical Substance Inventory were screened to remove inap-
propriate chemicals. The remaining chemicals were further ana-
lyzed for potential for adverse health and ecological effects and
for potential exposure. This process identified 407 chemicals with
both effects and exposure potential. An automated scoring step
was developed with scores based on effects potential, exposure
potential and annual consumption. Implementation of the auto-
mated scoring step has been postponed pending completion of
the TSCA Inventory update. In the interim, chemicals were se-
lected for detailed review at a workshop.
Plans to improve the process include adding additional TSCA In-
ventory chemicals to the initial list, identifying additional com-
puter-searchable descriptors for potential effects and adding ad-
ditional monitoring information. "While the new process is in need
of considerable improvement and refinement, it should provide
the foundation for continuous, automated chemical screening
and scoring that can be used by the ITC whenever the need
arises to select chemicals for detailed review," said Dr. Robert
Brink, the ITC's executive secretary.
Persons interested in learning the details may request a copy of
the ITC's interim report on the Sixth Scoring Exercise.
Page 8 of this issue of the Bulletin contains an explanation of the
legal authority for the existence of the TSCA Interagency Testing
Committee (ITC). Because of the interest in its work, the ITC re-
cently produced a brochure explaining its mission, scope, priority,
membership, review policy and process, scoring of chemicals
and the chemical nomination process. The brochure can serve as
a ready reference when questions arise as to how the ITC func-
tions. The TAO is distributing copies of the brochure upon re-
quest.

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EPA Proposes Amendments to PCB Rule
On July 8, 1987, EPA proposed (52 FR 25838) to amend the
Agency's July 10, 1984 rule on inadvertantly generated poly-
chlorinated biphenyls (PCBs) by excluding additional materials
from regulation. EPA has determined that activities involving
these materials do not present an unreasonable risk of injury to
health or the environment.
A July 10,1984 rule (called, the Uncontrolled PCB rule) permitted
the manufacture, processing, distribution in commerce, and use
of inadvertently generated and recycled PCBs under limited cir-
cumstances. Specifically, the Uncontrolled PCB rule excluded
from the TSCA bans, activities involving less than 50 ppm PCBs
which were generated in manufacturing processes which com-
plied with the rule's conditions limiting releases to air, water,
products, and wastes.
After the 1984 rule took effect, some companies and trade asso-
ciations filed petitions, under section 19 of TSCA, seeking judicial
review of the law. A settlement agreement outlining proposed
amendments to the July 10, 1984 rule was reached. The points
agreed to are included in the proposed rule issued on July 8,
1987.
Specifically, the July 8, 1987 proposed rule would eliminate from
the use authorization for PCBs in heat transfer and hydraulic sys-
tems the June 10, 1984 requirement that Viton"' elastomer gloves
be worn by workers performing maintenance on such systems.
The proposed rule also would exclude from the PCB ban on use
and distribution in commerce, certain equipment and materials
which have been adequately decontaminated.
The proposal also would amend the July 8,1984 definition of "re-
cycled PCBs." The redefinition would eliminate the condition lim-
iting the amount of Aroclor PCBs in water discharges from paper
recycling facilities and leave that control to individual NPDES per-
mits.
Certain restrictions remain on uses of waste oil containing any
detectable level of PCBs. The proposal adds a prohibition on
burning such oils in small, nonindustrial boilers.
The following TSCA rules were issued recently:
Trichlorobenzenes
On July 1,1987, EPA issued a phase II TSCA rule that specified
test standards and reporting requirements for environmental
effects testing of 1,2,3- and 1,2,4-tricblorobenzene (52 FR
24460). The CAS numbers for the two chemicals are 87-71-6
and 120-82-1. The chemical fate testing requirements in the
phase I rule [April 7, 1986 (51 FR 11728)] have been satisfied
and withdrawn.
Tetrabromobisphenol A
On July 6,1987, EPA issued a test rule requiring manufacturers
and processors of tetrabromobisphenol A (TBBPA) to perform
testing for chemical fate and environmental effects (52 FR
25219). The testing requirements for TBBPA (CAS No. 79-94-7)
include biodegradation studies in sediment/water and soil, an
acute toxicity study in freshwater algae, acute and early life stage
toxicity studies in fish, a partial life-cycle toxicity study in a benthic
invertebrate, a chronic toxicity study in an aquatic invertebrate
and bioconcentration studies in fish and invertebrates.
EPA Proposes Testing For DTBP
On June 25, 1987, EPA proposed that manufacturers and proc-
essors of 2,6-di-?ert-butylpenol (DTBP) test for chemical fate and
environmental effects (52 FR 23862).
The proposed rule was issued in response to an Interagency
Testing Committee designation of DTBP for priority consideration
for chemical fate, health effects and ecological effects testing
[November 19, 1985 (50 FR 47603)].
EPA is not proposing DTBP health effects testing at this time. The
Agency concluded that occupational exposures to the chemical
are low and intermittent, and fewer than 100 workers are proba-
bly involved. After reviewing available data the Agency concludes
human exposure to DTBP is extremely low and does not present
an unreasonable risk to human health.
DTBP (CAS No. 128-39-2) is a crystalline solid that is soluable in
many organic solvents. It is produced at sites in New York, South
Carolina and California. Annual production is estimated to be 24
to 34 million pounds per year. At least one firm imports DTBP. In
the United States, an estimated 75 to 95 percent of all DTBP is
used as a synthetic intermediate for the production of higher mo-
lecular weight phenolic antioxidants. DTBP is also incorporated
into fuels, oils, plastics, rubber and other products as an oxidation
inhibitor and stabilizer.
DTBP is expected to enter the environment mainly as a result of
water releases from sites where the substance is made and used.
DTBP is expected to be rapidly oxidized in air.
EPA Denies Citizen s Petition on PCBs
On July 2, 1987, EPA published the denial of a citizen's petition
calling for an amending of the TSCA definition of polychlorinated
biphenyls (PCBs); the petitioner wanted mono-, di-, and tri-
chlorobiphenyls to be excluded from the definition (52 FR 25068).
In denying the petition, filed under section 21 of TSCA, EPA said
Congress directed the Agency through section 6(e) of TSCA to
eliminate all PCBs from the environment. The Agency said it had
addressed the issue of excluding lower chlorinations of PCBs in
response to an earlier petition [August 25, 1982 (47 FR 37259)].
In the 1982 denial EPA acknowledged the technical merits
claimed regarding the relative risks of monochlorobiphenyls; nev-
ertheless, it denied the 1982 petition because of congressional
intent to include all chlorinated biphenyls. For addition informa-
tion about section 21 of TSCA, see page 8 of this issue of the
Bulletin.
EPA Issues Testing and Reporting Rule for Anthraquinone
On June 4, 1987, EPA issued a TSCA rule requiring manufac-
turers and processors of 9,10-anthraquinone (anthraquinone) to
perform certain chemical fate and environmental effects testing
and to report annually the volume manufactured or imported, dur-
ing the latest corporate fiscal year (52 FR 21018).
Under TSCA, importers are considered manufacturers. Section 8
of TSCA gives EPA reporting authority, and section 4, testing au-
thority.
The tests required under the anthraquinone rule are for water sol-
ubility, bioconcentration, sediment toxicity to benthic organisms
and acute toxicity to acquatic organisms.
4

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EPA Sets HDD and HDF Testing and Reporting Requirements
Ori June 5, 1987, EPA issued a TSCA rule requiring manufac-
turers and importers of 12 organic chemicals to test the sub-
stances for the presence of chlorinated and brominated dibenzo-
p-dioxins (HDDs) and dibenzofurans (HDFs). HDDs and HDFs
are recognized as having potential health and environmental sig-
nificance because of their potential for adverse toxic effects at
The rule names an additional 29 chemicals as precursors, and re-
quires companies which use one of these chemicals as a precur-
sor in the manufacture of another chemical to report certain infor-
mation to EPA. The precursor chemicals are:
very low doses.
The rule (52 FR 21412) will require testing of any of 20 additional
organic chemicals not currently manufactured or imported into
the United States if manufacturing or importation resumes.
The rule also requires manufacturers and importers of the 12
chemicals currently available in the United States to submit.
•	existing test data on HDD or HDF contamination
•	unpublished health and safety studies on HDDs and HDFs
•	consumer or worker allegations of significant adverse reactions
to HDDs and HDFs.
The same reporting information will be required for any of the 20
other chemicals if manufacturing or importation resumes.
The 12 chemicals currently manufactured in, or imported into, the
United States are:
CAS NO	CHEMICAL NAME
79-94-7	Tetrabromobisphenol-A
118-75-2	2,3,5,6-Tetrachloro-2-5-cyclohexadiene-1,4-
dione
118-79-6 2,4,6-T ribromophenol
120-83-2 2,4-Dichlorophenol
1163-19-5 Decabromodiphenyl oxide
4162-45-2 Tetrabromobisphenol-A-bisethoxylate
21850-44-2 Tetrabromobisphenol-A-bis-2,3-dibromopropyl
ether
25327-89-3 Allyl ether of tetrabromobisphenol-A
32534-81-9 Pentabromodiphenyl oxide
32536-52-0 Octabromodiphenyl oxide
37853-59-1 1,2-Bis(tribromophenoxy)-ethane
55205-38-4 Tetrabromobisphenol-A-diacrylate
The 20 chemicals not currently manufactured in, or imported into,
the United States that are subject to this rule are:
79-95-8	T etrachlorobisphenol-A
87-10-5	3,4,5-T ribromosalicylanilide
87-65-0	2,6-Dichlorophenol
95-77-2	3,4-Dichlorophenol
95-95—4	2,4,5-Trichlorophenol
99-28-5	2,6-Dibromo-4-nitrophenol
120-36-5	2[2,4-(Dichlorophenoxy)]-propionic acid
320-72-9	3,5-Dichlorosalicyclic acid
488-47-1	Tetrabromocatechol
576-24-9	2,3-Dichlorophenol
583-78-8	2,5-Dichlorophenol
608-71-9	Pentabromophenol
615-58-7	2,4-Dibromophenol
933-75-5	2,3,6-Trichloropbenol
1940-42-7	4-Bromo-2,5-dichlorophenol
2577-72-2	3,5-Dibromosaiicylanilide
3772-94-9	Pentachlorophenyl laurate
37853-61 -5	Bismethylether of tetrabromobisphenol-A
—	Alkylamine tetrachlorophenate
—	Tetrabromobisphenol-B
85-22-3
Pentabromoethylbenzene
87-61-6
1,2,3-Trichlorobenzene
87-84-3
1,2,3,4,5, Pentabromo-6-chlorocyclohexane
89-61-2
1,4-Dichloro-2-nitrobenzene
89-64-5
4-Chloro-2-nitrophenol
89-69-0
2,4,5-T richloronitrobenzene
92-04-6
2-Chloro-4-phenylphenol
94-74-6
4-Chloro-o-toloxy acetic acid
94-81-5
4-(2-Methyl-4-chlorophenoxy) butyric acid
95-50-1
o-Dichlorobenzene
95-58-7
o-Bromophenol
95-57-8
o-Chlorophenol
95-88-5
4-Chlororesorcnol
95-94-3
1,2,4,5-Tetrachlorobenzene
97-50-7
5-Chloro-2,4-dimethoxyaniline
99-30-9
2,6-Dichloro-4-nitroaniline
99-54-7
1,2-Dichloro-4-nitrobenzene
106-37-6
Dibromobenzene
106-46-7
p-Dichlorobenzene
108-70-3
1,3,5-Trichlorobenzene
108-86-1
Bromobenzene
108-90-7
Chlorobenzene
117-18-0
1,2,4,5-Tetrachloro-3-nitrobenzene
120-82-1
1,2,4-T richlorobenzene
348-51-5
o-Chlorofluorobenzene
350-30-1
3-Chloro-4-Muoronitrobenzene
615-67-8
Chlorohydroquinone
626-39-1
1,3,5-T ribromobenzene
827-94-1
2,6-Dibromo-4-nitromaine
Section 4 of TSCA gives EPA the authority to require testing and
section 8 gives the reporting authority. For additional information
on these sections see page 8 of this Bulletin.
SNUR Issued for 11-AA
On May 28, 1987, EPA published a significant new use rule
(SNUR) for 11-aminoundecanoic acid (11-AA). (52 FR 19860)
The Agency believes the substance may be hazardous to health
and certain uses of it may result in significant human exposure.
A significant new use of 11-AA is any use except when the sub-
stance is used:
•	as an intermediate in the manufacture of polymers in an en-
closed process and when 11-AA is expected to be fully poly-
merized during the manufacturing process, or
•	as a component in photoprocessing solutions.
The SNUR requires persons who intend to manufacture, import
or process 11-AA for a significant new use to notify EPA at least
90 days before beginning that activity. That notice will give EPA
time to evaluate the intended use and if necessary prohibit or limit
that activity before it begins.
EPA is also requiring, under section 8(a) of TSCA, manufac-
turers, importers and processors of 11-AA who are not covered
by the SNUR to notify the Agency of prospective manufacture,
import, or processing. Small businesses that manufacture, im-
port, or process 11-AA are exempt from the reporting rule.
5

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Section 8(e)... Substantial Risk
Below is a list of 16 initial section 8(e) notices recently placed in
EPA's public file. For an explanation of section 8(e)and how
copies of notices can be acquired see page 8 of this Bulletin.
Log No. 8EHQ-
Pages* CAS No.
0487-0661 S
Poly addition product of bischloromethyl-	63943-38-4
diphenyl and N,N,N',N'-
tetramethylhexanediamine	5
Summary results from a dermal sensitization study in guinea
pigs
0487--0666 S
A diallyl diglycol carbonate	5
Results of a dermal teratology study in rabbits
142-22-1
0487-0668
Xerographic toner	304
Protocol and interim findings from an ongoing chronic study of
a Xerox 9000-type photocopying toner by inhalation in rats
0487-0671
Pentachlorophenol and polychlorinated
dibenzo-p-dioxins	3
Report of accidental release
0587-0672 S
Di (2-ethylhexyl)phthalate
2-Ethylhexanol
2-Ethylhexanoic acid
Valproic acid
Results of an oral teratology study in rats
20
117-81-7
104-76-7
149-57-5
99-66-1
0587-0673
Bis(trichloromethyl) sulfone and	3064-70-8
Petroleum naphtha solvent (mixture) 56 64742-95-6
Final report from an acute (1-hour) inhalation study in rats
0587-0674 S
Sulfurized olefin and substituted
ammonium carboxylate (mixture) 110
Results of acute oral, dermal and inhalation studies and a 28-
day inhalation study in rats
Log No. 8EHQ-	Pages* CAS No.
0587-0675
Calcium naphthenate	408 61789-36-4
Final report from a chronic mouse skin-painting study
0587-0676
1,2-Dichloro-1,1-difluoroethane	2 1649-08-71
Preliminary results of a 90-day inhalation study in rats
0687-0677
Pyrazol Yellow BG 250% (C.I. Direct
Yellow 28)
Preliminary results of an Ames assay
8005-72-9
0587-0678
Pentachlorocyclopropane	8 6262-51-7
Preliminary results of acute oral and dermal toxicity studies in
rats
0687-0679
Reaction product of D-glucitol and
epichlorohydrin	165
Final reports from six genotoxicologic studies
68412-01-1
0687-0680
Di-, tri-, and tetraiodonaphthalenes
(mixture)	168
Final report from a repeated oral gavage study in rats
0787-0681
N-(cyclohexylthio)phthalimide	10 17796-82-6
Final results of a 2-year oncogenicity I chronic feeding study in
rats
0687-0682
Dodecylphenol	2 27193-86-8
Preliminary findings from an oral teratology study in rats
0687-0683
Bis(2-dimethylamino ethyl)ether	2 3033-62-3
Preliminary findings of a short-term repeated inhalation study in
rats
'S" at the end ot a Log Number means a sanitized versionis available.
1 Page count as ot publication date. New data are constantly being added to section
8(e) tiles. The page total at the time of request may exceed the 125-page cutoff and a
charge must be made. For additional information on obtaining section eight(e) files see
page 8 ot this issue.
EPA Issues Blphenyl Testing Rule
On June 3,1987, EPA issued a final Phase I rule for the chemical
biphenyl that requires industry to perform specific tests within a
scheduled time frame (52 FR 20710). The rule covers environ-
mental effects and chemical fate testing.
Biphenyl (CAS No. 92-52-4) was designated by the Interagency
Testing Committee for priority consideration by EPA [May 25,
1982 (47 FR 22585]. On September 12, 1985, EPA issued, under
two-phase rulemaking, a Phase I rule (50 FR 37182), On Decem-
ber 12, 1985 a biphenyl industry group submitted to EPA pro-
posed study plans and schedules for the required testing. EPA
rejected some of the plans and schedules. Revisions were made
by the industry group. The June 3, 1987 rule accepts the revised
plans and schedules.
CORR
The Office of Toxic Substances (OTS) is distributing a list of
chemical substances, chemical categories and mixtures that are,
or have been, subject to proposed or final TSCA regulations and
section 313 of the Superfund Amendments and Reauthorization
Act. The listing is called Chemicals on Reporting Rules Database
(CORR) and is available, as are all other free publications men-
tioned in this Bulletin, through the TSCA Assistance Office.
In CORR, individual substances are listed by Chemical Abstracts
Service (CAS) Registry Number. Categories of chemicals and
chemicals without CAS numbers are listed in alphabetical order
or by their TSCA premanufacture notice number. Each chemical,
mixture or category is followed by one or more rule codes. The
codes are explained in an index that includes information on Fed-
eral Register citations, the Code of Federal Regulations citations
and dates relevant to the rulemaking. CORR will be updated
quarterly. The most recent update includes OTS regulations
through June 30, 1987.
6

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Latest FYI Submissions
In recent weeks EPA received 12 FYI (For Your Information) sub-
missions. For additional information on FYls see page 8 of this
Bulletin.
Pages*
284
CAS No.
68-12-2
109-55-7
111-18-2
Log No. FYI
OTS-0587-0545
N,N-Dimethylformamide
Dimethylaminopropylamine
N,N,N,N,-Tetramethyl-1, 6-Hex
anediamine
Reports on 3 section 8(c) allegations, final results from guinea
pig maximization tests, acute oral and inhalation toxicity stu
ies, primary dermal irritation tests and an Ames mutagenicity
assay
OTS-0587-0548
1,1,1-Trichloroethane	71-55-6
Published report reviewing carcinogenicity bioassay results in
rats
unknown
OTS-0687-0549	36
Tungsten Carbide
Final results from an epidemiology study entitled "Mortality
Among Carbology Workers"
OT S-0687-0550	40
Bis(Tri-n-Butyltin) Oxide	56-35-9
Protocol and final report on a lifetime chronic toxicity and car-
cinogenicity study, a tentative evaluation for human safety,
and summarized results from a series of short-term toxicity
studies in rats
OTS-0687-0551	61
4-Chloro-2-Methylaniline	95-69-2
Thiourea	62-56-6
Published information on chemical and physical properties, pro-
duction, and use
Log No. FYI
Pages*
CAS No.
OTS-0687-0553	4
Diethylene Glycol Dimethyl Ether	111-96-6
Summarized results of a two week subchronic inhalation study in
rats
AX-0687-0554
Catalytically Cracked Clarified Oil
Solvent Refined Coal Distillate
39
64741-62-4
unknown
Solvent Henneu OUcll L/tOilliuiv
Preliminary report on limb bud tissue culture studies
AX-0687-0555	345
Light Catalytically Cracked
Naphtha	64741-55-5
Draft report on a 13 week subchronic inhalation study in rats
OT S-0687-0556	1
Nitrosamines	none
Nitrosomorpholine	59-87-2
Morpholine	110-91-8
Report on concentration levels found in water glycol hydraulic
fluids
OTS-0687-0557	60
Vinyl Fluoride	75-02-5
Draft report of results from an in vivo mutagenicity mouse micro-
nucleus test
AX-0787-0558	4
Benzidine	92-87-5
befa-Naphthylamine	91-59-8
Summarized results from an epidemiology study indicating ex-
cess kidney and bladder cancers in workers
"Page count as of publication date. New data are constantly toeing added to the FYI
tiles. It the page total at the time of a request exceeds ttie 125-page cutoff, a change
must be made. For additional information on obtaining FYI tiles see page 8 of this issue.
OTS-0687-0552
4,4'-Methylene-bis-2-Chloroaniline
Case report of worker bladder tumor
101-14-4
EPA Issues:
Hydroqulnone Test Standards, Reporting Requirements
On May 28, 1987 EPA published a rule that specifies certain
guidelines, protocols and schedules as the test standards and re
porting requirements for the testing of hydroquinone (5
19865).
This action results from the December 30,1995 issuance of a
rule by EPA establishing testing requirement under T
manufacturers of hydroquinone (CAS No. 128-31-9)-
time the Agency also proposed that certain TSCA test gui e in
and industry submitted protocols be used as the test s an ar
for the required studies. EPA also proposed that that test date
submitted within specified time frames. EPA reviewed comm
received on test guidelines and scheduling for hydroqui
issued the May 1987 rule.
The TSCA Guide for Chemical Importers/Exporters has been up-
dated. Volume I of the guide provides an overview of the require-
ments under sections 12 and 13 of TSCA. Volume II and the Ad-
dendum provide an alphabetical listing of the chemicals relevant
to these requirements. The two volume set is available through
the TAO.
EPA Sets Testing For DCBTF
On June 23,1987, EPA signed an enforceable testing consent
order with Occidental Chemical Corp. in which the company
agreed to perform certain chemical fate and environmental
effects tests on 3,4-dichlorobenzotrifluoride (DCBTF) (52 FR
23547).
EPA considers this action to be its response to the Interagency
Testing Committee's recommendation that the Agency consider
health effects, chemical fate and environmental effects testinq of
DCBTF [May 28,1984 (49 FR 22389],
7

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Substantial Risk... Section 8(e)
Under section 8(e), persons who obtain new information that rea-
sonably supports the conclusion that a substance or mixture
which they manufacture, import, process or distribute presents
substantial risk of injury to human health or the environment,
must notify EPA within 15 working (jays. These notices are then
reviewed by the Office of Toxic Substances (OTS) and an initial
evaluation (status report) is prepared containing, if appropriate,
followup questions to the submitter, referrals to other agencies,
and recommended OTS/EPA followup actions. The 8(e) notices
represent a company's first review of a situation and a judgment
in compliance with the statute to submit a notice within 15 work-
ing days of obtaining the information.
EPA publishes its status reports to make 8(e) information widely
available and understandable to a broad public. The submissions
and status reports are located in the OTS Public Reading Room,
ground floor, Northeast section, Waterside Mall, 401 M Street,
S.W., Washington, D.C.
Persons wishing to obtain a copy of a section 8(e) notice may
write: EPA, Freedom of Information, Ms. Jeralene Green (A-
101), Washington, D.C. 20460. There is no charge for duplicating
the first 124 pages, but at page 125 of a request for duplication
there is a $25.00 fee and a 20 cent charge for each additional
page (e.g., 126 pages will cost $25.20).
Single copies of the section 8(e) status reports (not the full sub-
missions) are available from the TAO.
Testing of Chemical Substances and Mixtures... Section 4
Section 4 of TSCA gives EPA authority to require manufacturers
or processors of chemicals to test the toxic effects of a desig-
nated substance. To require testing, EPA must find that the
chemical may present an unreasonable risk; that there are insuf-
ficient data available with which to perform a reasoned risk as-
sessment; and that testing is necessary to generate such data. A
test rule may also be based on an EPA finding of substantial pro-
duction and exposure to humans or the environment, in addition
to findings of insufficient data and need for testing.
Under section 4(e) an Interagency Testing Committee (ITC) was
established to recommend chemicals to EPA for priority consid-
eration for the promulgation of section 4 test rules. The ITC can
designate up to 50 chemicals or categories of chemicals for test-
ing and must make revisions to this section 4 priority list as
needed. In turn, EPA must respond within one year after the ITC
adds a substance to the priority list by starting rulemaking under
section 4 or giving reason for not doing so.
Section 8(a)... Preliminary Assessment Information Rule
Manufacturers (including importers) of chemical substances
listed in the section 8(a) rule must report certain production, use,
and exposure data to EPA using the rule's Report Form. EPA
may add chemicals to the rule when the Agency wishes to obtain
Preliminary Assessment Information of those substances.
For Your Information (FYI)
For Your Information (FYI) submissions are submitted voluntarily
to the Agency or to the Office of Toxic Substances (OTS) on
chemical toxicity and/or exposure. FYls are submitted by chemi-
cal manufacturers, processors and distributors, trade associa-
tions, labor organizations, Federal, State or local agencies, for-
eign governments, academia, public interest and environmental
groups, as well as by the general public. Microfiche copies of
these submissions are located in the OTS Public Reading Room,
ground floor, Northeast section, Waterside Mall, 401 M Street,
S.W., Washington, D.C. To obtain a copy of an FYI, follow the
procedure outlined under section 8(e) Substantial Risk just
above.
Citizens' Petition... Section 21
Under section 21 of TSCA any person may petition the EPA Ad-
ministrator to begin a proceeding for the issuance, amendment or
repeal of a rule under section 4,6 or 8 of TSCA, or an order undar
section 5(e) or 6(b) of the Act. Within 90 days after the petition is
filed the Administrator must either grant or deny the petition. The
Administrator may hold a public hearing or conduct an investiga-
tion or proceeding as deemed appropriate in order to determine
whether the petition should be granted. If the petition is denied,
the Administrator must publish the reasons for the denial in the
Federal Register. If the petition is granted, the Administrator must
promptly initiate an appropriate proceeding in accordance with
section 4, 5, 6 or 8 of TSCA.
TSCA Assistance Office (TS-799)	official awiimt
Office of Pesticides & Toxic Substances	"" "**
U.S.E.P.A.	tM0
Washington, D.C. 20460.
Firat Clan Mall
Potlag* and Fmi Paid
EPA
Parmlt Ho. Q-35
THE TSCA CHEM1CALS-IN-PROGRESS BULLETIN

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