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Office of Toxic Substances
(OTS)

T'i,
Vol. 9 No.1	January 1988
INSIDE
What's Happening in OTS—By Charles L. Elkins	2
Asbestos Hazard Emergency Response Action—By Michael M. Stahl	3
FIELD TESTING OF MICROORGANISM UNDER TSCA BEGINS	2
TSCA ENFORCEMENT ACTIONS
Company President Sentenced for PCB Disposal	4
Sheraton Corp. Fined $15,000 for PCB Violations	4
EPA Settles With Utility for PCB Violations	4
Hawaii Violated PCB Rule	6
Two Schools Fined for Asbestos-in-Schools Violations	4
ITC ADDS 6 CHEMICALS TO PRIORITY LIST	5
EPA PROPOSES CHANGES IN PCB TRANSFORMER FIRE RULE	5
AGENCY REQUIRES OLEYLAMINE TESTING	*	5
2-ETHYLHEXANOL FINAL TEST RULE ISSUED	8
AGENCY PUBLISHES PROPOSED SNUR FOR CBE	6
FOR YOUR INFORMATION
Asbestos Booklets	3
14 New FYls Available	7
OTS Receives 10 Substantial Risk Notices	7
Fish Toxicity Reports Available	6
Solvent Surveys Available	6
Clarification of TSCA Section 8(d) Submission Requirements	6
OECD Wforkshop: Cooperation on Existing Chemicals	2
TSCA Automated PMN Software Program	6
This news bulletin is intended to inform all persons concerned
with the Toxic Substances Control Act (TSCA) about recent de-
velopments and near-term plans. For further information or to re-
quest copies of documents mentioned, write the TSCA Assist-
ance Office (TAO), (TS-799) EPA, Washington, D.C. 20460, or
call (202) 554-1404.

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What's Happening in OTS—Charles L. Elkins
Risk assessment and risk management of toxic substances are
fields so new and so rapidly growing that it is vital to our success
for Government scientists and regulators to communicate and
consult with "outside" experts. As we enter a new year, I believe
it is essential for The Office of Toxic Substances (OTS) to con-
tinue and intensify our efforts to involve interested and affected
constituencies in major new policies and risk management
activities.
There are a number of ways to encourage public involvement in
OTS decisionmaking. One technique that worked well in
developing the rule implementing the Asbestos Hazard
Emergency Response Act (AHERA) was regulatory negotiation,
or "Reg-neg." In situations in which the probability of consensus
is high and all interested parties can be represented in a rela-
tively small group, "Reg-neg" can be an effective tool for explor-
ing and reaching agreement on important issues. The AHERA
"Reg-neg" was successful not only because the federally char-
tered group was able to agree on a proposed rule, which it then
recommended to EPA, but also because it gave the various inter-
ests represented an opportunity to hear and understand the
views of others.
Regulatory negotiation, if it results in a consensus produces a
regulation which the Agency commits itself to propose.
EPA issued a proposed AHERA rule on April 30, 1987 and solic-
ited public comment. The Agency also held a public meeting to
further insure that all interested parties had ample opportunity to
present their views. The rule, with minor changes became final
on October 22, 1987.
OTS also encourages less formal collaborative efforts. Two other
examples of very productive joint effort include:
•	the so-called "Generic SNUR," which is a proposed rule
(April 29, 1987, 52 FR 15594) to establish an expedited
process for followup on certain new chemical substances;
and
•	the "uncontrolled" PCB Rule, (July 8, 1987, 52 FR 25838)
that proposes several amendments to the 1984 regulation
on "Uncontrolled PCBs."
For other issues, different tech-
niques for obtaining public input
may be appropriate. For example,
in carrying out our responsibilities
under the Emergency Planning
and Community Right-to-Know
Act of 1986 (Title III of the Super-
fund Amendments and Reauthor-
ization Act), OTS has sought
advice and comment from all
interested parties on a number of
difficult questions. They include:
What kinds of information about
routine releases of toxic chemi-
cals should be reported? How
should this information be made
available to the public? How can we help prepare the public to
receive and understand the data? To get answers to these ques-
tions, we have held many public meetings; conducted a number
of informal discussions with a broad range of constituencies; and
provided opportunities for written comments and for peer review
of several documents.
In addition, OTS is taking the lead in developing a continuing
process for encouraging communication among industry,
environmental and public interest groups, state and community
officials, EPA and others on issues related to Title III implemen-
tation. This project, which we call "Common Ground,' will
attempt to find areas of agreement among these constituencies
on how to prepare the public to receive, understand and make
use of Title III data.
EPA Administrator Lee Thomas has repeatedly stressed the
need for the Agency to remain open and accessible to members
of the public representing different points of view, and to involve
as well as inform the public as we make decisions. OTS will
aggressively pursue this "fish bowl" policy in 1988, and we wel-
come your interest and participation.

OECD Workshop on Cooperation on Existing Chemicals
The Organization for Economic Cooperation and Development
(OECD) met in Ottawa, Canada during November 1987. Work-
shop participants agreed to a proposal which would establish an
international framework for the systematic investigation of exist-
ing chemicals. In addition, participants came to agreements in
principle to pursue specific multinational activities on 12 chemi-
cals. Different countries agreed to serve as clearinghouses for
the 12 chemicals or chemical groups of concern [see list below).
As a result of pre-workshop exchange of information from OECD
member countries, a computerized database was developed.
The database, known as EXICHEM, consists of data on existing
chemicals submitted by member countries. According to the pro-
posal, EXICHEM will become the heart of the framework and will
be refined and updated on an annual basis. The database will
be used to identify overlaps of ongoing or planned activities in
member countries on specific chemicals. National lists of priority
chemicals would also be used to identify opportunities for coop-
erative work.
OECD Chemical of Concern
1.	Zinc
2.	Pentachloroethane
3.	2,4- and 2,6-dinitrotoluene
Lead Country
Netherlands
USA
FRG
4.	Tributyl tin compounds
5.	Hexachloroethane
6.	Chlorobenzenes, mono to penta-
7.	Ammonia
8.	Acrolein
9.	1,1,2-trichloroethane
10.	1,1,1-trichloroethane
11.	Tetrabromobisphenol
12.	Nitrobenzene
France
FRG
Canada
UK
Sweden
USA
Denmark
USA
Japan
Field Test of Microorganism Under TSCA Begins
On October 19, 1987, the first field test of a recombinant-DNA
microorganism under TSCA was approved by Dr. John A. Moore,
EPA's Assistant Administrator for Pesticides and Toxic Sub-
stances. In early November 1987, Monsanto Agricultural Co.
began a field test of Pseudomonas aureofaciens, a genetically
engineered fluorescent pseudomonad, which will be used to
track engineered organisms in the environment. The field test,
executed in conjunction with Clemson University, is located at
the university's Edisto Research and Education Center, in Black-
ville, S.C.
2

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Asbestos Hazard Emergency Response Action—By Michael M. Stahl
On October 22, 1986, when President Reagan signed into law
the Asbestos Hazard Emergency Response Act (AHERA), EPA
had 180 days, until April 20, 1987, to propose rules, and until
October 17, 1987 to promulgate final rules. We had our work cut
out for us so we had to move quickly to meet these deadlines.
We decided to use an innovative approach—negotiated rulemak-
ing—to develop the proposed rules required by AHERA.
When EPA uses negotiated rulemaking to develop a proposed
rule, representatives of groups affected by the rulemaking serve
on a panel convened by EPA. The representatives work together
to reach consensus on the requirements of the proposed rule.
For the AHERA rule dealing with asbestos-in-schools, represent-
atives from unions, asbestos product manufacturers, schools,
education groups, States and EPA participated in the process.
Along with Susan Vogt, Deputy Director of EPA's Office of Toxic
Substances, I was one of the Agency's chief negotiators. The
2-monnthnnnegotiation process wastimeconsuming and occasion-
ally frustrating, but ultimately very satisfying. Despite a very
short deadline, the negotiating panel succeeded in fulfilling its
mission by developing a proposed rule within the timeframe
established by Congress.
The negotiating panel and EPA's staff did this only by working
long hours and weekends to bring the project to completion. The
opportunity to work in a cooperative fashion with a variety of
affected groups in negotiating the proposed rule stands out as
one of the most rewarding projects I have been involved with at
EPA.
The final rule changed very little from the proposed rule. Key
requirements of the rule include:
1)	accredited inspectors to visually inspect schools for
asbestos-containing material (ACM);
2)	reinspection of ACM by an accredited inspector every three
years, and periodic surveillance every six months of ACM;
3)	management plans be developed by local education
agency (LEA) by accredited planners for each school
under their administrative control;
4)	response actions be selected and implemented by each
LEA to address ACM as assessed by the accredited
inspector; and
5)	the use of accredited persons to conduct inspections, pre-
pare management plans for schools and carry out
response actions with respect to ACM in schools. Manage-
ment plans must be submitted to State governors.
$5 Million Asbestos Inspection and Management Plan Assist-
ance Program
To ease the burden on the schools of the new AHERA regula-
Asbestos Booklets Available
The TAO again has on hand three popular asbestos booklets
that are produced by the Office of Toxic Substances:
•	Asbestos in Buildings: Guidance for Service and Maintenance
Personnel
The asbestos information in this pocket size booklet should
be known to all maintenance personnel. A Spanish language
version is also available.
•	Asbestos in Buildings: Simplified Sampling Scheme for Fri-
able Surfacing Materials
tions the Agency developed the Asbestos Inspection and Man-
agement Plan Assistance Program (AIMPAP) to make available
to States $5 million to assist LEAs with the cost of conducting
inspections and developing management plans using accredited
inspectors and planners.
In October 1987, AIMPAP grants (ranging from $100,000 to
$500,000 per State) were awarded to 12 States. The recipients
may use the grant funds to:
1)	pay LEAs directly to offset the costs they incur for hiring
accredited inspectors;
2)	pay LEAs directly to offset the costs they incur for hiring
accredited management plan developers;
3)	purchase the services of accredited persons who will per-
form inspections or develop management plans for
schools; and
4)	pay State employees (who are accredited inspectors) to
perform inspections in schools.
Congress has appropriated funds to be used in fiscial 1988 for
these activities. States will soon receive application procedures
for the 1988 funds from EPA.
Inspector and Management Planner Accreditation
Seventeen cooperative agreements totaling $1.1 million were
awarded to 17 States to support development and implementa-
tion of training courses to accredit asbestos inspectors and
those developing management plans. The recipient States may
use the Federal financial assistance to support training delivered
directly by State employees, universities, or individuals approved
to teach courses. The Model Accreditation Plan, finalized in April
1987, is available and offers a model course which States may
use as a prototype in developing their own training course.
In conjunction with the announcement of the AHERA final rules,
EPA published a list of approved courses for accreditation of
inspectors and management planners. The list identifies course
locations across the United States. The courses are intended to
certify asbestos abatement workers, contractors, inspectors, and
management planners. In the year to come, OTS, in support of
AHERA activities, will provide a teleconference for school offi-
cials, conduct seminars for the State officials responsible for
management plan review, conduct compliance assistance visits
to schools, continue to develop and approve training courses,
and develop a guidance document outlining LEA responsibilities
under AHERA.
Describes a procedure for sampling friable sprayed or
troweled-on materials on ceilings, walls and other surfaces.
• Measuring Airborne Asbestos Following An Abatement
Action:
The guidance offered here addresses the question of how to
determine when an asbestos abatement work site has been
sufficiently cleaned. The question is set within the larger
framework of determining when the abatement work is com-
pleted and when to release the contractor, but it focuses on
the use of air sampling and analysis to determine work-site
cleanliness.
3

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Company President Sentenced For PCB Disposal
On Sept. 25, 1987, Arthur W. Paciesas was found guilty in the
Federal district court in Cincinnati of unlawfully disposing of
PCB-contaminated oil in that city. The oil had polychlorinated
biphenyl (PCB) concentrations of 50 parts per million or greater,
which means it could only have been disposed of in an EPA-
approved incinerator, or in an EPA-approved PCB chemical land-
fill.
•The conviction of Paciesas should serve as an example to oth-
ers who violate Federal regulations by illegally disposing of
PCBs." said Louis M. Halkias, special agent in charge of EPA's
region 5, Office of Criminal Investigations. "This type of prosecu-
tion was possible due to the strong commitment of region 5 not
only to regulate the proper handling and disposal of PCBs, but
also to pursue aggressively those individuals who knowingly
endanger public health," said Halkias, in Chicago.
Paciesas, president of Sea Bright Environmental Co., Inc., of
Cincinnati, who pleaded guilty to one count of illegal disposal of
PCBs received two years of probation. He is required to perform
100 hours of community service and is required to enroll in an
alcoholic treatment center.
In 1979, under TSCA, EPA banned the manufacture and dis-
tribution of PCBs, but allowed continued use of PCB fluids in
electrical transformers and capacitors as long as Federal regula-
tions were followed.
PCBs belong to a broad family of organic chemicals known as
chlorinated hydrocarbons. They are toxic, extremely stable, and
have been widely used in hydraulic systems, heat transfer sys-
tems, and as insulating fluid in electrical equipment. PCBs may
enter the body through the lungs, the gastrointestinal tract and
the skin. After absorption, PCBs are circulated in the blood
throughout the body and are stored in fatty tissues and in a vari-
ety of organs, including the liver, kidneys, lungs, adrenal glands,
brain, heart and skin.
Sheraton Fined $15,000 For PCB Violations
Sheraton Corporation has agreed to pay $15,000 as part of a
consent agreement for violating TSCAs PCB rule at its facility in
Honolulu.
On June 30, 1987, EPA's region 9 issued an administrative civil
complaint against the corporation for violations of the PCB rule.
The violations included failure to maintain inspection records for
PCB transformers currently in use, improper disposal of PCBs
and failure to maintain annual documents regarding the disposal
of PCBs and PCB items.
The consent agreement and final order requires Sheraton to
come into compliance with the PCB rule. The corporation has
agreed to accelerate the removal of PCB transformers at its
Honolulu facility.
EPA Settles With Utility For PCB Violations
EPA announced an agreement with Sierra Pacific Power Com-
pany for violations of TSCAs PCB Rule at the company's facili-
ties in the Reno, Nevada and Lake Tahoe, California areas. In
the consent agreement and final order, Sierra Pacific agreed to
pay a penalty of $23,000.
On March 13, 1987, EPA issued an administrative civil complaint
against Sierra Pacific for violations of the PCB rule. These viola-
tions included failure to properly mark PCB transformers and
other PCB items, failure to store PCBs for disposal in a proper
facility, improper use of PCB transformers and improper disposal
of PCBs. The consent agreement and final order requires the
company to come into compliance with the PCB rule. Addi-
tionally, Sierra Pacific has agreed to implement new policies
which would further reduce the risks associated with PCB equip-
ment. The company has also agreed to "use its best efforts" to
expend $200,000 for the accelerated removal of PCB trans-
formers which could legally remain in service.
IVvo Schools Fined for Asbestos-in-Schools Violations
Arizona
On October 16,1987, EPA announced an agreement with Phoe-
nix Christian High School in Phoenix, Arizona, for violation of the
TSCA Asbestos-in-Schools Rule.
"On August 1 1, 1987 EPA region 9 issued an administrative
complaint against Phoenix Christian High School for violating the
Asbestos-ln-Schools Rule," said Judith E. Ayres, Regional
Administrator of U.S. EPA region 9. "The purpose of this pro-
gram has been to ensure that public health is protected and that
our children are not threatened by exposure to friable asbestos
materials. I am pleased that we have reached an agreement with
Phoenix Christian High School and that the school intends to
correct all violations cited in the complaint."
The school has agreed to pay a fine of $300 and will provide
documentation to EPA certifying that recordkeeping and notifica-
tion violations have been corrected. The district further certified
that it will remove all of its asbestos at a cost of approximately
$13,000.
California
On October 16, 1987 EPA announced an agreement with the
Crossroads School of Santa Monica, California for violations of
TSCAs Asbestos-ln-Schools Rule.
"On March 25, 1987, EPA, region 9, issued an administrative
complaint against the Crossroads School for violating the
Asbestos-ln-Schools Rule," said Judith E. Ayres, Regional
Administrator of U.S. EPA, region 9. "The purpose of this pro-
gram has been to ensure that public health is protected and that
our children are not threatened by exposure to friable asbestos
materials. I am pleased that we have reached an agreement with
the Crossroads School and that the school intends to correct all
violations cited in the complaint."
The school has agreed to pay a fine of $300 and has provided
documentation to EPA certifying that record keeping and notifica-
tion violations have been corrected. The district further certified
that it shall remove all of its friable asbestos at their elementary
school at a cost of approximately $40,000.
The Asbestos-ln-Schools Rule does not require schools to abate
its asbestos-containing materials but EPA encourages schools to
do so when this action is appropriate.
4

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ITC Adds 6 Chemicals to Priority List
In its recently released 21st report to the EPA Administrator, the
Interagency Testing Committee (ITC) added six aminoanthra-
quinone dyes to the list of chemicals to be given priority consid-
eration by EPA. Genotoxicity testing but no chemical fate or
ecological effects testing is recommended by the ITC for each of
the six dyes. The dyes and their Chemical Abstracts Service
(CAS) numbers are:
Acid Blue 401
Acid form of Acid Blue 402
Acid Blue 453
Acid form of Acid Blue 454
Disperse Blue 565
Disperse Red 606
CA Index Names (9CI)
(CAS No. 6424-85-7)
(CAS No. 6247-34-3)
(CAS No. 2861-02-1)
(CAS No. 128-86-9)
(CAS No. 12217-79-7)
(CAS No. 17418-58-5)
1.	2-Anthracenesulfonic acid, 4-((4-(acetylamino)phenyl)
amino]-1 -amino-9,10-dihydro-9,10-dioxo-, monosodium salt
2.	2-Anthracenesulfonic acid, 4-[(4-(acetylamino)phenyl)
amino]-1-amino-9,10-dihydro-9,10-dioxo-
3.	2,6-Anthracenedisulfonic acid, 4,8-diamino-9,10-dihydro-
1,5-dihydroxy-9,10-dioxo-, disodium salt
4.	2,6-Anthacenedisulfonic acid, 4,8-diamino-9,10-dihydro-
1,5-dihydroxy-9,10-dioxo-
5.	9,10-Anthracenedione, l,5-diaminochloro-4,8-dihydroxy-
6.	9,10-Anthracenedione, 1 -amino-4-hydroxy-2-phenoxy-
For additional information about the ITC and section 4 of TSCA
see page 8 of this Bulletin.
The TSCA Section 4(e) Priority List
November 1987
Chemical/Group of Chemicals
Do = Ditto
Month of ITC
Designation
Designated for response within 12 months
1	Tributyl phosphate
2	Isopropanol
3	Methyl tert-butyl ether
Recommended with intent-to-designate
1 Ethylbenzene
1
2
3
4
Recommended but not designated for
response within 12 months
Diisodecyl phenyl phosphite
C.I. Disperse Blue 79
Methyl ethyl ketoxime
Acetamide, A/-[5-bis[2-(acetyloxy)
ethyl]aminoJ-2-[(2-bromo-4,6-
dinitrophenyl)azo]-4-methoxy phenylj-
Acetamide, W-bis[2-(acetyloxy)
ethy!)amino]-2-[(2-chloro-4,6-din-
itrophenyl)azo]-4-methoxy phenyl]-
Acetamide, A/-[5-bis[2-
(acetyloxy)ethyl]amino]-2-{2-chloro-4,6-
dinitrophenyljazo-4-ethoxy phenyl]-
Acid Blue 40
2-Anthracenesulfonic acid, 4-[(4-(acetyl-
amino)phenyl)amino]-1 -amino-9,10-
dihydro-9,10-dioxo-
Acid Blue 45
2,6-Anthracenedisulfonic acid, 4,8-
diamino-9,10-dihydro-l,5-dihydroxy-9,l0-
dioxo-
Disperse Blue 56
Disperse Red 60
7
8
9
10
11
12
11/86
5/87
Do
5/87
11/85
11/86
Do
5/87
Do
Do
11/87
Do
Do
Do
Do
EPA Proposes Changes In PCB Transformer Fire Rule
On August 21, 1987 (52 FR 31738) EPA proposed to amend its
July 17, 1985 (50 FR 29170) polychlorinated biphenyls (PCB)
Transformer Fires Rule. The 1985 rule required measures to
reduce and eliminate the fire-related risks posed by the use of
electrical transformers containing 500 parts per million (ppm) or
greater PCBs. Electrical transformers containing 500 ppm or
greater PCBs are called PCB Transformers.
The proposal would amend the 1985 PCB Transformer Fires
Rule by adding provisions and modifications to the rule. These
provisions and modifications include: (1) phasing out the use,
as of October 1, 1993, of all low secondary voltage network
PCB Transformers located in sidewalk vaults; (2) Allowing the
installation of PCB Transformers, in or near a commercial build-
ing, only in emergency situations; (3) Allowing the use of non-
sidewalk vault low secondary voltage network PCB Trans-
formers in or near commercial buildings without enhanced
electrical protection only until October 1, 1993, provided EPA is
notified as of October 1, 1990; (4) Allowing the installation of
retrofilled PCB Transformers for reclassification purposes; and
(5) Allowing the limited use of an alternative label on the exte-
rior of PCB Transformer locations provided certain conditions
are met.
After promulgation of the 1985 final PCB Transformer Fires
Rule, the Mississippi Power Company filed a petition for judicial
review under TSCA. The Mississippi Power Company, along
with intervenor National Electrical Manufacturer's Association,
and utility intervenors (as a class) entered into settlement nego-
tiations with EPA. During these settlement negotiations a settle-
ment agreement was drafted outlining proposed amendments to
the PCB Transformer Fires Rule.
EPA Requires Oleylamlne Testing
EPA issued a final TSCA rule on August 24, 1987 that requires
manufacturers and processors of oleylamine to test the chemi-
cal for potential health effects (52 FR 31962).
The rule requires an oral developmental toxicity study, and two-
tiered mutagenicity testing. EPA also will review data to deter-
mine whether third-tier mutagenicity and oncogenicity testing will
be needed.
In a related action, EPA proposed that the TSCA test guidelines
be used as the standards for oleylamine testing. This proposed
rule also was published on August 24, 1987 (52 FR 31970).
A major use of oleylamine where human exposure is likely to
occur is as an additive to petroleum lubricants or as an inter-
mediate in manufacture of these additives. The chemical also Is
used as a collector agent in ore flotation, in asphalt preparation,
in a concrete mold release agent and in the manufacture of
paper, paperboard and glues.
5

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Fish Toxicity Reports Available
FPA is distributing, with the cooperation of the U.S. Fish and
Wildlife Service, a document containing previously unpublished
data on the toxicity of a large number of organic chemicals to
fish. A new preface to this document, prepared by Dr. Robert
Lipnick, of OTS, reviews the use of these data in the develop-
ment of structure-activity relationships now being employed in
the premanufacture review process of TSCA.
Part 1 of the document, a 1953 report, contains data on more
than 3,400 chemicals tested for 24 hours using four species of
fish. The most toxic chemicals were studied further at 1.0, 0.1,
and 0.01 mg/L screening levels. The same toxicity test protocols
were employed in a 1954 study, which is part 2 of the document.
Both studies were conducted by the Fish and Wildlife Service at
its Kearneyville, West Virginia facilities. Part 1 also contains a
133-reference bibliography of the pre-1953 fish toxicity literature.
The TAO has a limited number of the more than 250-page docu-
ment, "The Toxicity of 3,400 Chemicals to Fish" and "The Tox-
icity of 1085 Chemicals to Fish." When the supply is exhausted
the reports can be bought from the U.S. Department of Com-
merce's National Technical Information Service.
Solvent Surveys Available
OTS now has available for distribution two surveys on chlorinated
solvents in household products. Household Solvent Products: A
"Shelf" Survey With Laboratory Analysis gives the analytical
results of approximately 1,200 household products tested for
any of the following six solvents-, methylene chloride,
perchlorethylene, trichloroethane, trichlorotrifluroethane, and car-
bon tetrachloride. The laboratory analysis was conducted on
household and automotive cleaning, painting, and lubricating
products purchased nationally during the summer of 1985.
Household Solvent Products: A National Usage Survey provides
statistics on the frequency and duration of consumer use of
these products, as well as user characteristics and brand prefer-
ences.
Both surveys are available through the TSCA Assistance Office.
Clarification of TSCA Section 8(d)
Submission Requirements
On November 20, 1987 (52 FR 44826) EPA made a tech-
nical amendment to the TSCA section 8(d) model rule
submission requirements to clarify how studies should be
submitted. EPA issued the clarification because many
section 8(d) studies have been submitted without clearly
identifying to which chemical they apply. Under this
amendment to 40 CFR §§ 716.30(b) and 716.35(b), all
section 8(d) submissions must be identified either on the
face of the study or otherwise by the applicable chemical
name and Chemical Abstracts Service Registry Number
(CAS Number), if any, identified in § 716.120(a)(1) and
(2). This indexing or identification could be done in three
ways. First, the cover letter which is required under
§§ 716.30(b) and 716.35(b) could clearly index each
study by CAS Number and chemical name. Second, a
separate attachment could be included in the submission
which identifies each of the studies by chemical name
and CAS Number. Finally, each individual study could
include the CAS Number and chemical name on its first
page or on a cover page. While other means of com-
pliance may be available, the Agency is most concerned
that the chemical name and CAS Number associated with
each study be easily ascertainable from the study, the
cover letter, or an attachment.
TSCA Automated PMN Software Program
A unit within OTS, the Information Management Division, has
completed revisions on a computer software program which
facilitates the preparation of the TSCA section 5 Premanufacture
Notification (PMN) form. The software prototype includes the
programs needed to automate completion of the PMN submis-
sion.
The program is written in Microsoft BASICA. It will operate on
the IBM personal computer (PC), the COMPAQ PC, and other
IBM PC compatibles, using MS-DOS operating system and
BASICA. The primary objective of the program is to facilitate
easy preparation of the PMN form.
The program displays instructions for preparing the submission
and for providing responses for each individual block on the
form. When the form is completed, companies may print out
both confidential and non-confidential copies of the PMN sub-
mission on a blank sheet of paper, overlay it with the appropriate
transparency, and copy the material. Both copies of the PMN
submission must be submitted to EPA as indicated in the May
13, 1983 notice (48 FR 21722) which details the statutory
requirements for section 5(a)(1) PMNs.
At this time, only paper copies of the PMN submission are
acceptable to EPA. The floppy diskette containing the responses
should not be submitted to EPA.
For more information contact Ms. Eyvone Petty of the Con-
fidential Data Branch (TS-793) on 202-475-7444. Copies of the
diskette, manual, and transparencies are available in limited
quantities from the TSCA Assistance Office at 202-554-1404.
CBE Proposed SNUR Published
On September 4, 1987, EPA published a proposed significant
new use rule (SNUR) for 1 -chloro-2-bromoethane (CBE) (52 FR
33606). The Agency believes the substance may be hazardous
to human health and/or the environment and that any use of the
substance may result in significant human or environmental
exposure. The proposed SNUR would require persons who
manufacture, import, or process CBE for any use to notify EPA
at least 90 days before beginning the activity. The required
notice would provide EPA with the opportunity to evaluate the
intended use and, if necessary, prohibit or limit the activity
before it occurs.
Hawaii Violated PCB Rule
On October 9, 1987, EPA announced an agreement with the
State of Hawaii for violations of the TSCA's PCB Rule at the
Waiawa Correctional Facility in Waipahu, Hawaii. In the consent
agreement and final order, the State of Hawaii agreed to pay a
penalty of $8,925.
On March 4, 1987, EPA issued an administrative civil complain
against the Waiawa Correctional Facility for violations of the PCB
rule. These violations included failure to maintain inspection rec-
ords for PCB transformers in use, failure to register its PCB
transformers with appropriate fire response personnel, improper
storage of PCB-contaminated transformers and improper dis-
posal of PCBs. The consent agreement and final order requires
the facility to come into compliance with the PCB rule. Addi-
tionally, the facility has assisted in accelerating the removal of all
PCB transformers and associated switches at the Waiawa facility
which could legally remain in service. This removal will be over-
seen by the U.S. Army Corps of Engineers. The facility was orig-
inally owned by the Department of Defense and maintained by
U.S. Army Support Command, Hawaii. The property was trans-
ferred from the United States government to the State of Hawaii,
Department of Social Services and Housing in 1985.
6

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Latest FYI Submissions
In recent weeks, EPA received 16 initial FYI (For Your
tion) submissions. For additional information on F s, s
8, of this bulletin.
Log No. FYI-
Chemical Name
Pages*
CAS No
QTS-0787-0559	2 632~79~1
Tetrabromophthalic anhydride	unknown
Ethylenebistetrabromophthalic imide	„rnhie>ms
Report of 2 worker complaints concerning respiratory prom
OTS-0787-0560	62 540-84~1
2,2,4-Trimethylpentane	629—14—1
Ethylene glycol dimethyl ether	onpsis
Draft report from an in vitro mouse lymphoma mu
assay
OTS-0787-0561	12 l23-01-3
study in hairless mice.
20
unknown
19
unknown
67-68-5
AX-0887-0562
Petroleum distillate, C9 fraction	reproduction
Preliminary report on a range-finding mhalafton repro
toxicity study in rats
AX-0887-G563
Petroleum distillate, C9 fraction
Dimethyl sulfoxide	measuring sister
Draft report on an in vitro cytogenetic ass; y	(ef Qvary
chromatid exchange frequencies in C
(CHO) cells
AX-0867-0564
Octane
Draft
667-0564	55 111-65-9
report on an in vitro mouse lymphoma mutagenes'
OTS-0887-0565 S	14	unknown
Polymer/solvent	, ¦ itv stucjy in rats
Summarized results of an acute inhalation to
OTS-0887-0566	64 95-48-7
Ortho-cresol	108-39-4
Meta-cresol	106-44-5
Para-cresol	, „ „aliane to New
Draft report on a dose range-finding study Y 9
Zealand White rabbits
OTS-0887-0567 s	1 confidential
PMN Chemical	. . , nW/i synthesis
Summarized final results from an Unsche u chromosome
Assay, a CHO-HGPRT Mutation Assay, and a onru
Aberration Assay
OTS-O887-0568	41 75-09-2
Methylene chloride	inHiratina excess
Final results from an epidemiology study	employees,
breast and gynecological cancers among female employ
OTS-0887-0569	6 ,11-96-6
Methylene glycol dimethyl ether
Notice of Material Safety Data Sheet changes
OTS-0887-0570	7 unkn0wn
Diphenyl methylene diisocyanate	26471-^2-5
~t£X2SZ. -*—«rSTJUST
nary functions among polyurethane flexible
AX-0887-0571	19
Petroleum hydrocarbons	unknown
Draft report on an in vitro sister chromatid exchange assay in
Chinese Hamster Ovary (CHO) cells
OT S-0887-0572	>1,000
UV stabilizers	unknown
Chimassorb 944	none
Tinuvin P	2440-22-4
Tinuvin 326	3896-11-5
Full final reports from a variety o1 toxicological studies,
exposure data, and health and safety information
Section 8(e)... Substantial Risk
Below is a list of 10 initiaf TSCA Section 8(e) notices recently
placed in EPA's public files. For an explanation of Section 8(e)
and how copies of the notices can be obtained, please see page
8 of this Bulletin.
Pages*
CAS No-
Log No. 8EHQ
0787-0684 S	a
Proprietary mixture of siloxane poly-
mers, other organic substances
and a metal salt	Confidential
Preliminary results from a surgical implantation study in rats
0787-0685	152
Pentaerythritol tetraglycidyl ether	3126-63-4
Final reports from several in vitro genotoxicity studies
0787-0686 S	461
Modified alkyl phenol	Confidential
Final report from a 2d-day oral gavage study in rats
0887-0687	4
Hydrodesulfurized heavy vacuum
gas oil	64742-86—5
Preliminary results from a chronic skin-painting study in mice
0887-0688	2
Muriatic acid production process
Preliminary findings from an epidemiologic study in workers
24
0887-0689
Isoprene
Chloroprene
Finai report of a genotoxicity study in mice
78-79-5
126-99-8
0897-OB90
N-Phenyl maleimide	941-69-5
Preliminary report of a sensitization study in guinea pigs
0887-0691 S	3
Petroleum process streams
Preliminary results of chronic skin-painting study in mice
o
0987-0692
Alkali metal carboxylate	Confidential
Preliminary results of chronic exposure studies in mice and rats
0987-0693	130
Tetraethylene glycol	112-60-7
Final reports from in vitro and in vivo genotoxicity studies
"S" loftowi-„
•Page count as o( the publication date. New data are constantly being added to EfWs
Section 8(e) files. The page total at the time oi request may exceed the 125-page cut-
off and a photocopying charge must be made. For further infocmaiion on obtaining
TSCA Section 8(e) submissions, please see page 8 of this issue.

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2-Ethylhexanol Final Test Rule Issued
A final test rule requiring manufacturers and processors of
2-ethylhexanol to conduct a two-year oncogenicity bioassay was
published in the Federal Register on August 3, 1987 (52 FR
28698) and became effective on September 16, 1987.
The rule requires bioassays in rats and mice. Results will be
used to determine whether 2-ethylhexanol poses an unreason-
able cancer risk to humans. The chemical is used as an inter-
mediate in the manufacture of other chemicals.
Substantial Risk ... Section 8(e)
Under section 8(e), persons who obtain new information that
reasonably supports the conclusion that a substance or mixture
which they manufacture, import, process or distribute presents
substantial risk or injury to human health or the environment,
must notify EPA with 15 working days. These notices are then
reviewed by the Office of Toxic Substances (OTS) and an initial
evaluation (status report) is prepared containing, if appropriate,
followup questions to the submitter, referrals to other agencies,
and recommended OTS/EPA followup actions. The 8(e) notices
represent a company's first review of a situation and a judgment
in compliance with the statute to submit a notice within 15 work-
ing days of obtaining the information.
EPA publishes its status reports to make 8(e) information widely
available and understandable to a broad public. The submis-
sions and status reports are located in the OTS Public Reading
Room, first floor, East Tower, Waterside Mall, 401 M Street,
S.W., Washington, D.C.
For Your Information (FYI)
For Your Information (FYI) submissions are submitted voluntarily
to the Agency or to the Office of Toxic Substances (OTS) on
chemical toxicity and/or exposure. FYls are submitted by chemi-
cal manufacturers, processors and distributors, trade associa-
tions, labor organizations, Federal, State or local agencies, for-
eign governments, academia, public interest and environmental
groups, as well as by the general public. Microfiche copies of
these submissions are located in the OTS Public Reading Room,
ground floor, Northeast section, Waterside Mall, 401 M Street,
S.W., Washington, D.C. To obtain a copy of an FYI, follow the
procedure outlined under section 8(e) Substantial Risk just
above.
Persons wishing to obtain a copy of a section 8(e) notice may
write: EPA, Freedom of Information, Ms. Jeralene Green
(A-101), Washington, D.C. 20460. There is no charge for
duplicating the first 124 pages, but at page 125 of a request for
duplication there is a $25.00 fee and a 20 cent charge for each
additional page (e.g., 126 pages will cost $25.20).
Single copies of the section 8(e) status reports (not the full sub-
missions) are available from the TAO.
Testing of Chemical Substances and Mixtures... Section 4
Section 4 of TSCA gives EPA authority to require manufacturers
or processors of chemicals to test the toxic effects of a desig-
nated substance. To require testing, EPA must find that the
chemical may present an unreasonable risk; that there are insuf-
ficient data available with which to perform a reasoned risk as-
sessment; and that testing is necessary to generate such data. A
test rule may also be based on an EPA finding of substantial pro-
duction and exposure to humans or the environment, in addition
to findings of insufficient data and need for testing.
Under section 4(e) an Interagency Testing Committee (ITC) was
established to recommend chemicals to EPA for priority consid-
eration for the promulgation of section 4 test rules. The ITC can
designate up to 50 chemicals or categories of chemicals for test-
ing and must make revisions to this section 4 priority list as
needed. In turn, EPA must respond within one year after the ITC
adds a substance to the priority list by starting rulemaking under
section 4 or giving reason tor not doing so.
TSCA Assistance Office (TS-799)
Office of Pesticides & Toxic Substances
U.S.E.P.A.
Washington, D.C. 20460.
Official BuiIimu
Penalty tor Private Um
$300
Flrat Clait Mall
Poilag* and Fhi Paid
EPA
Pwmlt No. G-35
THE TSCA CHEMICALS-IN-PROGRESS BULLETIN

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