Chemicals-in-Progress Bulletin Office of Toxic Substances (OTS) U.S. Environmental Protection Agency Vol. 12 No. 1 January 1991 Voluntary Program Aimed at Reducing Toxic Releases Toxic Chemicals Initiative is Announced The Environmental Protection Agency is asking industry to voluntarily reduce its emissions of 17 toxic chemicals. In announcing the program, EPA Administrator William Reilly called for 1988 releases to be reduced 33 percent by 1992 and cut in half by 1995. The program, named the Industrial Toxics Pro- ject and frequently referred to as the 17-Chemicals Initiative, is part of a pollution prevention strategy that also includes sections focusing on the agricultural and energy sectors and federal facilities. The industrial initiative aims to achieve reduc- tions in releases to all environmental media, as well as reductions in transfers of chemical wastes to off- site management facilities. EPA anticipates that most of these reductions can be accomplished by eliminating wastes at the source, rather than rely- ing on destructive treatment after wastes have been generated. EPA recognizes that not every company or facility that handles one or more of these chemicals will be able to reduce emissions by 50 percent. Con- versely, many facilities will be able to achieve con- siderably larger reductions. The goals are meant as guidelines for a broad national effort. As the 17- Chemicals Initiative proceeds and gains momentum, EPA may identify additional chemicals and set more ambitious goals. The initiative will use 1988 Toxic Release Inventory data as a yardstick for measur- ing progress. Voluntary Reduction Commitments The core of this new effort is the establishment of voluntary commitments from industry. Nine com- panies have already entered into voluntary agreements with EPA to collectively achieve an 83 percent reduction in their toxic air emissions by 1993. The agreements were worked out in the sum- mer of 1989 when Administrator Reilly met with leaders of these companies, which EPA staff had Continued on page 3 r HIGHLIGHTS Page Mark Greenwood is named OTS director 2 ITC revises TSCA section 4(e) priority list 8 TSCA section 8(e) voluntary audit program begins 16 TSCA section 8(e) notices 16 FYI submissions 29 ------- Changes at the Top Mark Greenwood is New OTS Director Mark A. Greenwood became director of the Office of Toxic Substances on December 10,1990. For the past two years, Mr. Greenwood was Associate General Counsel for the Pesticides and Toxic Substances Division of EPA's Office of General Counsel. Mr. Greenwood joined EPA's Office of General Counsel in 1978 after receiving his law degree from the University of Michigan, where he also earned a graduate degree in public policy. He became the first Assistant General Counsel for the Resource Conser- vation and Recovery Act in 1983 and served as the Assistant General Counsel for Superfund from 1987 to 1988. Charles Elkins Moves to Office of General Counsel Charles L. Elkins, who directed the Office of Toxic Substances for four years, has accepted a new position in EPA's Office of General Counsel. His responsibilities will include coordination of activities involving the Office of General Counsel and the Office of Policy, Planning, and Evaluation. During his tenure, Mr. Elkins helped to set the Toxic Substances Control Act (TSCA) testing pro- gram on a new course, with multichemical generic rules and an active voluntary testing program; he also led the efforts to use TSCA's existing chemicals authorities more effectively. Revised PMN Form Available Soon Pollution Prevention Emphasized The Office of Toxic Substances (OTS) has re- vised the Premanufacture Notice (PMN) Form for New Chemical Substances (EPA Form #7710-25) and the Instructions Manual for Premanufacture Notification of New Chemical Substances. In the new form, PMN submitters are being strongly encouraged to provide information about pollution prevention and recycling activities associated with the new chemical substance. The agency will use this information in its evaluation of the new substance, which includes a comparison of the new substance's relative risk as a substitute for substances currently on the market. The information will also improve the agency's ability to consider issues of relative risk and toxics use reduction dur- ing review of PMN substances. The new form also provides space for submit- ters to indicate their willingness to be bound to prac- tices described in the notice that are designed to protect against unreasonable risk of injury to health or to the environment. The changes in the form reflect PMN regulations promulgated since 1984, when the form was last revised. Single copies of the PMN form and manual are available through the TSCA Assistance Information Service (TSCA Hotline). See page 32 for information about contacting the hotline. Submitters can photo- copy the form if additional copies are needed. The form and manual are also being provided to trade associations for circulation. OECD Report Now Available The Organisation for Economic Cooperation and Development (OECD) has conducted a survey of notification procedures in member coun- tries. The report, which was prepared in 1989 for an international workshop on new chemical notification systems, provides coverage of legal frameworks, notification procedures, assessment approaches, experience to date, regulatory ac- tions, and international aspects of new chemical notification systems. Single copies of the report, OECD Environment Monographs: A Survey of New Chemicals Notification Procedures in OECD Member Countries, are available through the TSCA Assistance Information Service (TSCA Hotline). See page 32 for information about con- tacting the hotline. 2 January 1991 ------- Toxic Chemicals Initiative is Announced Continued from page 1 identified as operating facilities that, due to air emis- sions, presented exceptionally high levels of risk. Through the Industrial Toxics Project, EPA is opening the voluntary program to the hundreds of other facilities that release substantial amounts of the 17 priority chemicals. Project staff members are working out the details of how the process will work, and they will soon begin to arrange meetings be- tween corporate leaders, Administrator Reilly, and other EPA managers. EPA will make every effort to see that reductions achieved under this initiative can be applied, where appropriate, as reduction credits under the Clean Air Act. Industrial Toxics Staff To implement the Industrial Toxics Project, Linda Fisher, EPA's Assistant Administrator for Pesticides and Toxic Substances, has established the Special Projects Office, whose staff will work across program and environmental lines in the 17 Chemicals Targeted Benzene Cadmium and compounds Carbon tetrachloride Chloroform Chromium and compounds Cyanides Dichloromethane Lead and compounds Mercury and compounds Methyl ethyl ketone Methyl isobutyl ketone Nickel and compounds Tetrachloroethylene Toluene Trichloroethane Trichloroethylene Xylene(s) agency. Susan Hazen has been appointed director of the office. Ms. Hazen can be reached at (202) 382-3761 for additional information. TRI Reporting Expanded by New Pollution Prevention Law In the closing hours of its 101st session, Con- gress passed the Pollution Prevention Act of 1990. The new law formalizes many of the pollution preven- tion activities already in place at EPA and creates new activities. The law significantly expands the Toxics Release Inventory (TRI); it requires collection of man- datory information on pollution prevention beginning with the 1991 reporting year. In the forms submit- ted by July 1992, all facilities subject to TRI report- ing will be required to submit an additional "source reduction and recycling report." The new re- quirements include reporting of the following infor- mation: waste quantities prior to treatment or recycling, and the percentage change in this quantity from the previous year (not including one-time events, such as accidents); amounts recycled on-site and off-site, percentage change from the previous year, and types of recycling practices; types of source reduction practices in use; amounts anticipated for the next two years of total wastes and quantities recycled; production index data to track changes in the level of economic activity at a facility; techniques used to identify source reduction op- portunities; and amount of releases resulting from one-time events. Other Major Provisions of the Law Section 4 calls for EPA to establish an Office of Pollution Prevention and to create a strategy that, among other objectives, measures pollution prevention, integrates pollution prevention into ex- isting programs, and improves public access to environmental data collected under all statutes implemented by EPA. Section 5 establishes a federal program for grants to states for technical assistance. Section 6 creates a computer-accessible informa- tion clearinghouse. January 1991 3 ------- TRI Reporting/Form R Avoid These Common Errors Ever since EPA began collecting data annually for the Toxic Release Inventory (TRI), agency staff and industry have been working with EPA's Form R. This year, agency staff compiled a list of the errors most commonly found on the form. Take a look at these 12 errors before starting to fill out Form R this year: 1. Invalid chemical identification. The CAS number and chemical name reported on page 3 of Form R must exactly match the listed CAS number and chemical name. Chemical categories should not be reported with a CAS number. A generic chemical name should be provided only if you are claiming the section 313 chemical identity as trade secret. Chemical names should be taken directly from the list published with the annually up- dated Form R and instruction package. Mixture names should be entered in part III, section 1.4 , if they are the sole identification. 2. Failure to consider a listed chemical qualifier. A number of chemicals are required to be reported only if they exist in certain forms. For example, aluminum, vanadium, and zinc are qualified as "fume or dust." Isopropyl alcohol and saccharin have manufacturing qualifiers. Ammonium nitrate and ammonium sulfate are qualified as solutions. Phosphorus is qualified as yellow or white. Asbestos is qualified as friable. Check the Form R package for a complete list of these chemicals, which must be reported with the appropriate qualifier in paren- theses. 3. Missing certification signature. An original certification signature must appear on page 1 of every Form R submitted to EPA. 4. Incomplete forms. A complete Form R report for any toxic chemical category consists of at least five pages stapled together. Pages 1 and 2 may be photocopied to com- plete each report only if the information on page 1 and 2 is the same for each report submitted. An original certification signature is required on each page 1, even if the rest of the information is photocopied. Any package that is sent containing a page 1 and a page 2 with several page 3's, 4's, or 5's will result in a Notice of Noncompliance. 5. Missing or invalid reporting year. The reporting year is the calendar year during which the reported data were collected; it is not the year in which the form is sent to EPA. Forms are due to EPA by July 1, 1991, for the chemicals manufac- tured, processed, or otherwise used during calen- dar year 1990. A Form R cannot contain data for more than one year; "1990/1991" is not correct. Also, it is essential that the reporting year be pro- vided by the submitter. Omission of information will result in a Notice of Noncompliance. 6. Maximum amount on-site left blank. Leaving part III, section 4, on page 3 of Form R blank will result in a Notice of Technical Error. 7. Questionable data. Data submitted to EPA are checked by machine. Frequently flagged mistakes include the following: Zip codes are missing or do not correspond to the city and county reported. County names are missing or misspelled. SIC codes are incorrectly reported with alphabetic characters rather than the correct four-digit numeric code. Dun and Bradstreet numbers for both the reporting facility and the parent company are frequently reported in alphabetic characters or in a format that does not correspond to the Dun and Bradstreet number format. Information about Publicly Owned Treatment Works (POTWs) is often missing or does not include street address, county, and zip code. In addition, releases to POTWs are often reported on page 4 when there is no POTW listed on page 2. Release information must be reported in pounds; facilities often report it in tons, gallons, or other units of measure. 8. Incorrect completion of trade secret infor- mation. The responses to trade secret questions must be Continued on next page 4 January 1991 ------- Avoid These Common Errors on Form R Continued from page 4 complete and consistent. If trade secrecy is in- dicated, the submission must be accompanied by a trade secret Form R, a sanitized Form R, trade secret substantiation, and sanitized substantiation. Failure to provide complete trade secret information will result in a Notice of Noncompliance. 9. Revisions not identified. Facilities submitting revisions to previously sub- mitted data should provide them to EPA in the follow- ing manner: (a) make corrections in red ink on a photocopy of the Form R that was originally sub- mitted; (b) mark the photocopy "VOLUNTARY REVI- SION" in the space marked "FOR YOUR OPTIONAL USE" on page 1 of the form; (c) include the original certification signature on the revision; and (d) send the photocopy to the EPCRA Repor- ting Center. Failure to correctly identify a revision may result in EPA's entering it in the database as a new submission, leading in the appearance of in- creased emissions from the facility. A copy of the revision must also be sent to the appropriate state organization. 10. Duplicate submissions not identified. Facilities sometimes send EPA multiple copies of the same Form R to ensure that it is received. Duplicate submissions must be identified by printing "DUPLICATE" in red ink on page 1 in the space marked "FOR YOUR OPTIONAL USE ONLY." Failure to correctly identify a duplicate report may result in duplication of the data in the database and the appearance of increased emissions from the facility. 11. Reporting for delisted chemicals or chemicals not on the section 313 list. The reporting package for the current year always contains an updated list of the chemicals for which TRI data must be reported. Although "over- reporting" will not result in a Notice of Non- compliance or Notice of Technical Error, data reported for chemicals not on the current TRI list are not entered in the TRI database. Therefore, it does not serve any purpose to report this information to EPA. 12. Data "linkages" are not identified. Some of the information reported on pages .1 and 2 is related to information reported on pages 3, 4, and 5. For example, stream names are reported on page 1 as streams A, B, or C; releases of the chemical to the streams are reported on page 3, in section 5, blocks 5.3.1, 5.3.2, and 5.3.3. It is necessary for the submitter to enter the stream code (A, B, or C) in the appropriate box, next to the cor- responding release value reported on page 3. The same is true for off-site locations and POTWs that are reported on page 2, with corresponding releases reported on page 4. Failure to enter the codes to establish these linkages may result in a Notice of Technical Error. Call Toll-Free for Help EPA has established a toll-free hotline to help industry correctly fill out Form R. The hotline is staffed Monday through Friday (federal holidays excluded) from 8:30 to 5:00 Eastern time. Just call (800) 535-0202. New Computer Program Makes TRI Reporting Easier EPA is including computer programs for Toxic Release Inventory (TRI) reporting in the 1990 Form R packages that were mailed to industry in January 1991. This reporting software will allow companies to enter data onto an online Form R. Through the use of edit checks and validation, the software will en- sure the data meet EPA specification. The software is for use on IBM PC-compatible (MS- DOS) systems with floppy or hard disks. The floppy diskette containing Form R data can be submitted to EPA. Some states will also accept TRI reporting on a floppy diskette. For those that re- quire paper submissions, the EPA software will print a facsimile form that can be photocopied. Also included with the reporting software is documentation on how to load and use the program. EPA received more than 80,000 TRI submissions for the 1989 reporting year. More than 4,500 of these were provided on floppy diskettes. For the 1990 reporting year, the agency expects 20,000 to 24,000 submissions to be made on diskette. January 1991 5 ------- Toxic Release Inventory Section 313 Petitions Petitions Denied Action Date of Federal Register Chemical Submitter Requested Receipt Publication Date INORGANIC FLUORIDES SAFE WATER FOUNDATION OF TEXAS LIST 11/25/86 05/29/87 ORTHOPHENYLPHENOL DOW CHEMICAL COMPANY DELIST 04/30/87 10/29/87 COBALT AND COMPOUNDS HALL CHEMICAL COMPANY DELIST 05/15/87 12/03/87 NICKEL AND COMPOUNDS HALL CHEMICAL COMPANY DELIST 05/15/87 12/03/87 MANGANESE AND COMPOUNDS HALL CHEMICAL COMPANY DELIST 05/15/87 12/03/87 ETHYLENE CHEMICAL MANUFACTURERS ASSOCIATION DELIST 07/13/88 01/27/89 PROPYLENE CHEMICAL MANUFACTURERS ASSOCIATION DELIST 07/13/88 01/27/89 CYCLOHEXANE CHEMICAL MANUFACTURERS ASSOCIATION DELIST 09/09/88 03/15/89 CADMIUM SELENIDE SCM CHEMICALS DELIST 04/14/89 10/19/89 CADMIUM SULFIDE SCM CHEMICALS DELIST 04/14/89 10/18/89 DECABROMODIPHENYL OXIDE GREAT LAKES CHEMICAL DELIST 05/15/89 11/03/89 Cr/Sb/Ti BUFF RUTILE DRY COLOR MAMUFACTURERS ASSOCIATION DELIST 06/27/89 01/08/90 ANTIMONY COMPOUND SYNTHETICS PRODUCT COMPANY DELIST 09/05/89 02/13/90 ZINC BORATE HYDRATE US BORAX RESEARCH DELIST 09/07/89 03/20/90 SULFURIC ACID ECOLAB, INC. DELIST 12/12/89 06/18/90 PHOSPHORIC ACID ECOLAB, INC. (WITHDRAWN) DELIST 12/14/89 06/25/90 ZINC ZULFIDE ORE & CHEMICAL CORP. DELIST 01/29/90 08/01/90 Petitions Granted Chemical Submitter Federal Register Action Date of Publication Date Requested Receipt Proposed Rule Final Rule TITANIUM DIOXIDE DUPONT DE NEMOURS AND CO. DELIST 08/24/87 02/19/88 06/20/88 TITANIUM DIOXIDE SCM & DIDIER TAYLOR DELIST 08/19/87 02/19/88 06/20/88 TITANIUM DIOXIDE DIDIER TAYLOR (SEE SCM) DELIST 08/19/87 02/19/88 06/20/88 TITANIUM DIOXIDE KEMIRA DELIST 10/06/87 02/19/88 06/20/88 CI ACID BLUE 9 ECO. AND TOX. ASSN. OF DYE MFGRS. DELIST 10/06/87 04/12/88 10/07/88 CI ACID BLUE 9 ECO. AND TOX. ASSN. OF DYE MFGRS. DELIST 10/06/87 04/12/88 10/07/88 MELAMINE CRYSTAL MELAMINE CHEMICAL COMPANY DELIST 10/07/87 06/20/88 03/29/89 SODIUM HYDROXIDE SOLUTION CHLORINE INSTITUTE INC. DELIST 04/22/88 12/09/88 12/15/89 SODIUM SULFATE HOECHST CELANESE DELIST 08/09/88 02/17/89 06/20/89 ALUM. OXIDE (NON-FIBROUS) ALUMINUM ASSOCIATION, ET AL. DELIST 09/30/88 04/12/89 02/14/90 SEVEN CFCs AND HALONs NRDC AND GOVERNORS LIST 01/09/90 03/21/90 08/03/90 Petitions Pending Action Date of 180-Day Chemical Submitter Requested Receipt Deadline PHOSPHORIC ACID THE FERTILIZER INSTITUTE DELIST 11/19/90 05/18/91 SULFURIC ACID ENVIRONMENTAL POLICY CENTER MODIFY 12/24/90 06/29/91 Continued on next page 6 January 1991 ------- How to Obtain TRI Data There are a number of ways to gain access to the Toxic Release Inventory (TRI). * Through a computer network. Online access is available from the National Library of Medicine's TOXNET. To obtain an account call (301) 496-6531, or write TRI Representative, Specialized Information Services, National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894. Account holders also have access to other National Library of Medicine databases on toxicology, health, and chemical substances. At the library. Other forms of access are available to the public from federal depository and public libraries. The names and addresses of the public libraries that have the TRI on fiche are listed in the Directory of Public Libraries; depository libraries holding the fiche or CD- ROM in their collection are listed in Federal Depository Libraries: Your Source for the Toxic Release Inventory. This information is also available from the TRI Hotline. By choosing any of these formats to pur- chase. Both the Government Printing Office and the National Technical Information Service sell TRI data on CD-ROM, COMfiche, magnetic tape, and in report form. In addition, the National Technical Information Service also sells the data on microcomputer diskette. Are you looking for state-specific data? Online information for specific states is available through TOXNET. Environmental release data for each state can also be purchased on COMfiche from the Government Printing Office and on COMfiche or microcomputer diskette from the National Technical Information Service. TRI Hotline For a list of the libraries that provide TRI access to their community or to obtain a brochure, "Public Access to the Toxic Release Inventory," call EPA's Community Right-to-Know Hotline at (800) 535-0202. In Washington, D.C., and Alaska, call (202) 479-2449. To purchase TRI data, contact U.S. Government Printing Office National Technical Information 710 North Capitol St., NW Service Washington, D.C. 20401 U.S. Department of Commerce Phone: (202) 783-3238 (COMfiche and paper) 5285 Port Royal Road (202) 275-0186 (magnetic tape and CD-ROM) Springfield, VA 22161 Phone: (703) 487-4650 TRI Section 313 Petitions, continued Proposed Rules Proposed Rule Action Date of Federal Register Chemical Submitter Requested Receipt Publication Date BUTYL BENZYL PHTHALATE CI PIGMENT BLUE 15 CI PIGMENT GREEN 7 CI PIGMENT GREEN 36 AMMONIUM SULFATE (SOLN) TEREPHTHALIC ACID BARIUM SULFATE BARIUM SULFATE MONSANTO CHEMICAL COMPANY DELIST 02/09/87 07/20/87 DRY COLOR MANUFACTURERS ASSOCIATION DELIST 06/01/68 05/15/89 DRY COLOR MANUFACTURERS ASSOCIATION DELIST 06/01/88 05/15/89 DRY COLOR MANUFACTURERS ASSOCIATION DELIST 06/01/88 05/15/89 ALLIED SIGNAL, INC. DELIST 01/23/89 03/30/90 AMOCO CORPORATION DELIST 07/27/89 02/15/90 PESA DELIST 08/07/89 02/12/90 DC MA DELIST 09/19/89 02/12/90 January 1991 7 ------- Interagency Testing Committee Issues New List of Chemicals for Study TSCA Section 4(e) Priority List Revised The Interagency Testing Committee (ITC) was established under section 4(e) of the Toxic Substances Control Act (TSCA). The ITC, which con- sists of representatives from 18 federal organiza- tions, screens, selects, and recommends chemicals and chemical groups for priority testing con- sideration. These chemicals may present an unreasonable risk of injury to health or the environment, may reasonably be anticipated to enter the environment in substantial quantities, or may involve significant or substantial human exposure. The ITC recom- mends chemicals or chemical groups for health ef- fects, chemical fate, or ecological effects testing to eliminate testing information deficiencies. Congress directed the ITC to recommend chemicals or chemical groups to EPA for priority testing. These recommended chemicals and chemical groups are contained in the TSCA Section 4(e) Priority List. The ITC is required to designate those chemicals or chemical groups, from among its recommendations, to which EPA shall respond by initiating rulemaking under TSCA section 4(a) or by publishing its reasons for not initiating rulemaking. At least every six months, the ITC revises the TSCA Section 4(e) Priority List. Congress also directed the ITC to take advan- tage of the unique and automatic TSCA section 8 reporting requirements developed for the ITC. In its April 1990 report on chemical testing, the General Accounting Office was highly critical of the ITC for not taking advantage of these automatic reporting requirements. The ITC was directed to develop pro- cesses for utilizing production, importation, and ex- posure information submitted under section 8(a) to determine when recommended chemicals should be withdrawn and for utilizing chemical fate, ecological effects, and health effects data submitted under sec- tion 8(d) to determine when recommended tests should be withdrawn. The testing recommendations for chemicals or chemical groups that have been added to the TSCA Section 4(e) Priority List are listed below. Designated In its 27th Report, the ITC designated two chemicals that were previously recommended with intent-to-designate. 4-Vinylcyclohexene Testing: Health effects. Rationale: The National Institute for Occupational Safety and Health (NIOSH) nominated 4-vinylcyclohexene to the ITC to review TSCA sec- tion 8 information and to reduce health effects and occupational exposure concerns through implemen- tation of testing recommendations. Further ITC Activity: Reviewing additional NIOSH chemicals. Continued on next page Chemicals Deferred from Further Consideration For the first time, the Interagency Testing Committee (ITC) deferred almost 700 chemicals from further consideration because the chemicals were not reported to EPA or to the U.S. Interna- tional Trade Commission as being recently pro- duced. The group of deferred chemicals included 429 aldehydes, 83 sulfones, 80 isocyanates, and 95 brominated flame retardants, all of which are no longer commercially available. Four Integrated Risk Information System (IRIS) chemicals were deferred and returned to EPA, because the ITC's review identified health effects data that appear to be sufficient to reduce the uncertainty associated with risk assessments, because there were uncertainties related to testing under TSCA, or because domestic and in- ternational production volumes are being substan- tially reduced. Deferred and other chemicals are recycled through the ITC's computerized processes to identify chemicals whose production volumes have substantially changed. 8 January 1991 ------- TSCA Section 4(e) Priority List Revised Continued from page 8 Sodium cyanide Testing: Chemical fate and ecological effects. Rationale: The U.S. Department of the Interior nominated sodium cyanide to learn about unpub- lished studies conducted by industry and to reduce ecological effects concerns through implementation of testing recommendations. Further ITC Activity: The Agency for Toxic Substances and Disease Registry is reviewing the health effects of cyanide. In its 27th Report, the ITC designated one chemical group. Integated Risk Information System (IRIS) Chemicals Testing: Chemical fate, health effects, or ecological effects. Rationale: EPA nominated the IRIS chemicals to the ITC to increase the confidence in the data and reduce the uncertainties in the assessment of risk. EPA nominated IRIS chemicals to the ITC to take advantage of (1) the ITC's comprehensive network- ing and information exchange capabilities that con- serve resources and promote cost-effective testing required or sponsored by U.S. government organiza- tions and (2) the opportunity to obtain recent produc- tion and exposure information and unpublished health and safety studies that are automatically re- quired under TSCA sections 8(a) and 8(d), respec- tively, for any ITC recommendation. Four of the six designated chemicals are listed in the 1990 Clean Air Act amendments and were designated for inhala- tion toxicity testing. Further ITC Activity: Reviewing additional IRIS chemicals; reviewing TSCA section 8(a) and section 8(d) submissions on the recommended chemicals. Recommended with Intent-to-deslgnate In its 27th Report, the ITC recommended with intent-to-designate one chemical group. Aldehydes Testing: Ecological effects. Rational: EPA nominated aldehydes to the ITC because insufficient data existed to reasonably determine or predict the ecological effects of aldehydes submitted to EPA as new chemicals. Aldehydes were selected for a comprehensive analysis of a substructure-based chemical group and to obtain recent production and exposure informa- tion and unpublished health and safety studies that are automatically required under TSCA sections 8(a) and 8(d), respectively, for any ITC recommendation. Further ITC Activity: Reviewing TSCA section 8(a) and section 8(d) submissions. Recommended In its 27th Report, the ITC recommended one chemical and three chemical groups. One of these recommended groups comprises two additional IRIS chemicals; the rationale for this recommendation is similar to the rationale for the designated IRIS chemicals except that the ITC wanted an opportunity to review the TSCA section 8 information before making a designation decision. N-phenyl-1 -naphthylamine Testing: Chemical fate, health effects, and ecological effects. Rationale: The Occupational Health and Safety Ad- ministration (OSHA) nominated N-phenyl-1-naph- thylamine to the ITC in an ongoing effort to identify chemicals for which permissible exposure limits may be proposed and to obtain recent production and ex- posure information and unpublished health and safety studies that are automatically required under TSCA sections 8(a) and 8(d), respectively, for any ITC recommendation. Further ITC Activity: Reviewing additional OSHA chemicals; reviewing TSCA section 8(a) and section 8(d) submissions. Sulfones Testing: Physical and chemical properties. Rationale: Sulfones were selected because of their commercial significance and because insufficient data existed to reasonably determine or predict physical and chemical properties. Sulfones were selected for a comprehensive analysis of a Continued on page 10 January 1991 9 ------- TSCA Section 4(e) Priority List Revised Continued from page 9 substructure- based group and to obtain recent pro- duction and exposure information and unpublished health and safety studies that are automatically re- quired under TSCA sections 8(a) and 8(d), respec- tively, for any ITC recommendation. Further ITC Activity: Reviewing TSCA section 8(a) and section 8(d) submissions. Substantially produced chemicals in need of sub- chronic tests Testing: Subchronic toxicity. Rationale: This group was selected because of substantial production, commercial significance, potential occupational or consumer exposures, potential accidental releases, and the lack of suffi- cient data to reasonably determine or predict sub- chronic effects. It was selected for a comprehensive analysis of a substantially produced chemical group with a minimum of existing easily available health effects data and to obtain recent production and exposure information and unpublished health and safety studies that are automatically required under TSCA sections 8(a) and 8(d), respectively, for any ITC recommendation. Further ITC Activity: Reviewing TSCA section 8(a) and section 8(d) submissions. Summary of Revisions to the TSCA Section 4(e) Priority List Chemical or Chemical Group ITC Action Recommendation Source 4-Vinylcyclohexene Designated NIOSH Sodium cyanide Designated DOI IRIS chemicals Designated EPA Aldehydes Recommend with intent-to-designate EPA and the ITC's computerized, substructure- based processes IRIS chemicals Recommended EPA N-phenyl-1 -naphthylamine Recommended OSHA Sulfones Recommended ITC's computerized substructure-based processes Substantially produced chemicals in need of subchronic tests Recommended ITC's computerized substructure-based processes 10 January 1991 ------- OECD Develops Voluntary Testing Program for High-Production-Volume Chemicals The Organisation for Economic Cooperation and Development (OECD) has piloted a voluntary program to develop test data for screening and set- ting priorities on international high-production- volume chemicals. The program is part of the OECD's Screening Information Data Set (SIDS) effort. (See accompany- ing article.) For the pilot, 53 chemicals were chosen from among the 1,300 industrial chemicals that are produced in the largest quantities worldwide. Four- teen of the 24 OECD member countries, including the United States, agreed to participate in the cooperative program, and during the past year, these nations prepared dossiers containing all the available information worldwide for each chemical. All but one of the dossiers were submitted for review at an OECD expert meeting in November. The last dossier is expected to be completed early this year. At the meeting, testing decisions were made for 30 of the pilot chemicals. More than 250 tests were identified and agreed to as being needed to fill out the SIDS test sets on those chemicals. Ten chemicals were judged to have incomplete SIDS dossiers and were deferred for review to January 1991. Decisions on seven chemicals were deferred pending resolution of exposure issues. Five chemicals were judged to have complete SIDS sets; assessments for these five will be prepared by the responsible countries in anticipation of a subsequent OECD review to set priorities for further assessment or testing. In most countries, including the United States, industry is voluntarily handling the respon- sibility and costs of testing. Before the pilot chemicals can be tested, several issues remain to be resolved. Among these, the most important is how to handle exposure-based exemptions from SIDS-level testing. A few OECD countries supported using exposure exemptions dur- ing the pilot, though the United States and most other OECD members did not. A compromise ap- proach was agreed upon for the pilot: nations that supported using the exposure exemptions agreed to handle replacement chemicals for which exposure exemptions were not an issue. The question of ex- posure exemptions is to be resolved at an OECD ex- pert meeting scheduled for March 1991. A second round of dossier preparation for 94 chemicals is scheduled to begin in July 1991. Continued on page 12 Some Background In 1988, member countries of the Organisation for Economic Cooperation and Development (OECD) agreed that a basic level of test data was needed on chemicals produced in the largest quantities worldwide. Referred to as high-production-volume chemicals, these industrial chemicals are manufac- tured in excess of 1,000 tons a year in two or more member countries or in excess of 10,000 tons a year in one member country. Using this guidance, 14 of the 24 OECD member countries compiled an inventory of more than 1,300 high-production-volume chemicals. This set of chemicals was then examined and grouped by characteristics and data availability. About 500 of these chemicals were characterized as being of potential health or environmental concern, yet little if any test data were publicly available to assist in their assessment. In November 1989, the United States and other OECD member countries agreed to initiate an inter- national testing program to generate the data needed to screen these chemicals and set priorities for further testing or assessment. A Screening In- formation Data Set (SIDS) of testing and information was created for this purpose by the OECD, and 53 chemicals were chosen for a pilot testing program. The SIDS set of tests contains the following data elements: Production/Use Physical/Chemical Properties Environmental Fate Ecotoxicity Acute studies in fish, Daphnia, and algae Health Effects Acute toxicity 45-day subchronic toxicity test with reproductive and developmental toxicity screens Mutagenicity (assays for gene mutations and chromosome aberrations) January 1991 11 ------- Firm to Pay Record $3.75 Million Fine In September 1990, CWM Chemical Services, Inc., of Chicago, Illinois, agreed to pay a civil penalty of $3.75 million, the largest administrative penalty ever imposed on a single facility by EPA. The consent agreement was the outcome of a civil administrative complaint filed by EPA that charges CWM with failing to comply with federal regulations on disposing of polychlorinated biphenyls (PCBs) at a plant in Chicago. Following notification by CWM that it had failed to monitor stack emissions on four occasions in 1986 and 1987, an EPA investigation uncovered (1) four additional periods in which stack emissions did not appear to be monitored; (2) 111 days during which air pollution control equipment did not appear to be operated in accordance with the company's Toxic Substances Control Act (TSCA) permit; and (3) an apparent failure to record the rate and quantity of PCB solids fed to the incinerator. The $3.75 million penalty was reduced from $4,329 million on the basis of CWM's voluntary in- itial report to EPA, the company's payment of penalties of $53,000 to the state of Illinois and $300,000 to the Illinois Hazardous Waste Fund, and the company's substantial improvement of its monitoring operations. CWM Chemical Services, Inc., is a subsidiary of Chemical Waste Manage- ment, Inc. OECD Develops Voluntary Testing Program for High-Production-Volume Chemicals Continued from page 11 The United States has been a leader in pursu- ing international cooperation in chemical testing and assessment. The successful implementation of the SIDS program is tangible proof that nations can "share the burden" of testing to ensure the safe use of chemicals around the globe. Continuing interna- tional cooperation is needed because of the large number of high-production-volume chemicals that re- quire assessment and testing and because of the international nature of the chemical industry. Through the SIDS program, OECD countries can also sort out and understand the differences in their approaches to hazard and risk assessment. It is hoped that this increased understanding will lead to a common approach to assessment around the world. Equally important to the international coopera- tion evidenced in the SIDS effort are the steps taken domestically to support the program's development and implementation. Starting in 1988, under the auspices of a dialogue group convened by the Con- servation Foundation, various federal agencies, the chemical industry, and environmental groups have met to sort out their differences and to develop solid positions in support of the SIDS effort. This strong support has enabled EPA's Office of Toxic Substances to play a major leadership role in developing and implementing the SIDS effort. For More Information About The SIDS Program... The results of the Screening Information Data Set (SIDS) program will be available to all countries through the International Registry of Potentially Toxic Chemicals (IRPTC) and the International Pro- gramme for Chemical Safety (IPCS). The Chemical Manufacturers Association (CMA) is coordinating the efforts of U.S. industry in this voluntary program and is actively looking for sponsors for upcoming SIDS chemicals. For infor- mation concerning CMA's efforts, please contact Sandra L. Tirey, CMA, 2501 M Street, N.W., Washington, D.C. 20037; telephone, (202) 887-1274; FAX, (202) 887-1237. If you would like additional information about the SIDS program, please contact Charles Auer, Director, Existing Chemical Assessment Division (TS-778), Environmental Protection Agency, 401 M Street, S.W., Washington, D.C. 20460; telephone, (202) 382-3442; FAX, (202) 475-8168. 12 January 1991 ------- EPA Consolidates Three Actions Against Firm into One Case Multimedia Approach The Environmental Protection Agency (EPA) has charged a facility in Puerto Rico with violations under three environmental laws. What makes the case unusual is that the agency has rolled these multimedia enforcement actions into one case. By consolidating the multimedia enforcement actions, the agency is underscoring the fact that the facility may have problems with its environmental management and control systems across the board. Included among the charges are failure to file information required by the Emergency Planning and Community Right-to-Know Act (EPCRA) and infrac- tions of the Resource Conservation and Recovery Act (RCRA) and the Clean Water Act. The enforcement actions against the facility, which is owned by the Caribbean Petroleum Cor- poration, are as follows: Under RCRA, EPA is seeking a $685,325 civil penalty against the Caribbean Petroleum Cor- poration for storing hazardous waste for more than 90 days without filing a permit applica- tion and failing to comply with other re- quirements for a hazardous waste storage facility. Under the Clean Water Act, EPA is seeking a $40,000 civil penalty against the Caribbean Petroleum Corporation for failure to protect water resources in the event of a leak and for failure to implement an adequate spill preven- tion control and countermeasure plan for the above-ground tanks in which oil is stored. Under EPCRA, EPA is seeking a civil penalty of $42,000 against the Caribbean Petroleum Corporation for failure to report information about aluminum oxide for the 1987 and 1988 reporting years. (Effective in reporting year 1990, aluminum oxide was removed from the list of chemicals required to be reported under EPCRA.) Ruling Upholds Use of State Inspectors for TSCA Enforcement Program State personnel can be designated by EPA to inspect facilities under the Toxic Substances Con- trol Act (TSCA), an EPA administrative judge has ruled. In 1989, EPA filed a complaint against the Connecticut-based Litton Industrial Automation Systems Inc., alleging improperly marked and stored polychlorinated biphenyls (PCBs), which are regulated under section 6(e) of TSCA. The EPA com- plaint was based on an inspection conducted by two inspectors from the Connecticut Department of En- vironmental Protection. Litton maintained that TSCA does not authorize EPA to delegate its reponsibilities to states and moved to suppress the evidence which the two Con- necticut inspectors obtained. In an order issued on October 25,1990, Judge Frank W. Vanderheyden concluded that section 28 of TSCA authorizes the EPA administrator to engage state officials as TSCA inspectors. "Connecticut's compliance inspection program enhances EPA's efforts to control unreasonable health risks by conducting additional inspections which the Administrator would be unlikely to dispatch without the additional support provided by state per- sonnel," the judge wrote. "Thus, the plain meaning of section 28's language is broad enough to encom- pass EPA's interpretation that section 28 authorizes the funding of state programs to conduct TSCA com- pliance inspections." Litton has filed an appeal of the penalty assess- ment, and the case will now proceed to a hearing. January 1991 13 ------- Cleanup of Great Lakes Basin is Set as Agencywide Priority Over the past 20 years, the United States and Canada have struggled to reverse decades of damage to the Great Lakes. In that time, im- provements in sewage treatment and controls on direct discharges of industrial wastes have dramatically improved the lakes' water quality. But it hasn't been enough. Today, scientists and environmentalists on both sides of the border recognize nonpoint pollution as the greatest threat to the health of the Great Lakes basin. Toxic chemicalsmore than 800 of them have turned up in samples of water, bottom sediments, and fish taken from the lakes. At least half of these toxins entered the lakes from the at- mosphere, and their presence underscores the dif- ficulties in developing solutions to the persistent and complex environmental problems in the Great Lakes. EPA Sets Priority What is EPA doing to resolve these problems? First, it has established restoration of the Great Lakes as an agencywide priority. As a result, atten- tion has shifted from traditional water pollution con- trol measures to development of a comprehensive, risk-based, multimedia five-year plan to protect the Great Lakes. Second, EPA is taking the view that the Great Lakes basin is an ecosystem requiring integrated management of resources outside, as well as inside, of the agency. EPA's Great Lakes National Program Office has already created strong working relation- ships with Environment Canada, which is simultaneously developing its own remediation pro- gram; the eight states bordering the lakes; and other federal agencies with roles in restoration of the Great Lakes. New Approach "The Great Lakes offer the agency a test of how to integrate all our tools to solve environmental pro- blems," Christopher Grundler, director of EPA's Great Lakes National Program Office, said. "Nowhere else in the nation can such an approach to resolving environmental problems be demon- strated as well as it can here." A distinguishing difference of the Great Lakes project lies in the way EPA has broadened its defini- "The Great Lakes Program offers a new model for doing business at EPA. All the agency's offices In the regions and In headquarters are pulling together- through pollution prevention Initiatives, research, vigorous enforcement, and rallying the publicto focus on two primary goals: reducing toxics and restor- ing water quality In the natural systems that sustain life." EPA Administrator William K. Reiily tion of environmental problems. For example, EPA will be considering the close link between the lakes' health and the regional economy. It will also be pay- ing attention to ecological risks to fish and wildlife in addition to human health risks. Pollution Prevention The agency has not yet decided how it will define success. But one objective on Christopher Grundler's list is the disappearance of advisories about eating fish caught in the Great Lakes. Achiev- ing this will require pollution prevention strategies, which are expected to play an important part in the agency's overall strategy. "Our goal for the long run is to be able to eat fish without the numerous advisories now in place," he said. "Without source reduction of toxics in the Great Lakes basin, we will simply not reach the levels necessary to have an unlimited supply of edi- ble fish. Simply tightening point source releases of toxics is not enough." Correction The address for the TRI Reporting Center was listed incorrectly in the last issue of Chemicals-in-Progress Bulletin. The correct ad- dress is Title III Reporting Center, P.O. Box 23779, Washington, D.C. 20026-3779. The TRI Reporting Center will make data and reports from individual facilities available in its public reading room and, on a limited basis, will conduct sear- ches and provide printouts on request. 14 January 1991 ------- EPA Issues Interim Assessments ol CFC Substitutes A preliminary evaluation of a number of aqueous and terpene cleaners, hydrofluorocarbons, and hydrochlorofluorocarbons indicates that they can be safely substituted for chlorofluorocarbons (CFCs) in many uses, assuming the proper controls are in place. Since the United States banned use of CFCs in nonessential aerosols in 1978, there has been a growing international effort to halt the depletion of the Earth's stratospheric ozone layer. Last year, both the United States and the international community tightened their restrictions on the use and produc- tion of CFCs and extended these restrictions to in- clude other chlorinated compounds as well. (See accompanying article.) These efforts will not be suc- cessful, however, unless safe chemical substitutes can be found. EPA evaluated aqueous and terpene cleaners as partial replacements for CFC-113 and methyl chloroform in metal and electronics cleaning. Hydrofluorocarbons and hydrochlorofluorocarbons were studied for their uses in mobile air condition- ing, refrigeration, foam insulation, electronics and metal cleaning, and sterilization. In making its findings public, the agency pointed out that the reports are based on the data available at the time of publication and will be revised as more data are generated. While these interim reports can be used by chemical manufacturers, processors, equipment manufacturers, users, and others to make near-term decisions, they should not be inter- preted as a final judgment. The technical support documents for the interim reports are included in the "CFC Substitutes Ad- ministrative Record." This record is available to the public in the TSCA Public Docket Office from 8 a.m. to 4 p.m., Monday through Friday, excluding legal holidays. The TSCA Public Docket Office is located in room NE-G004, 401 M Street, S.W., Washington, D.C. Single copies of the interim reports, Aqueous and Terpene Cleaning and Hydrofluorocarbons and Hydrochlorofluorocarbons, can be obtained from the TSCA Assistance Information Service. See page 32 for information on how to contact the information service. Montreal Protocol Tightens Restrictions In June 1990, the Montreal Protocol on Substances That Deplete the Ozone Layer was amended to include more stringent international pro- visions. Under the revised protocol, all fully halogenated CFCs and carbon tetrachloride will be phased out by 2000; halons will also be phased out by 2000, with ex- emptions for essential uses; methyl chloroform will be phased out by 2005. In addition, the nations involved in the protocol issued a nonbinding declaration calling for hydrochlorofluorocarbons to be used only when alternatives are not feasible, with phaseout by 2020, if possible, but no later than 2040. These restrictions are based on a series of recently completed scien- tific, economic, and technological assessments prepared by the parties to the protocol. New Publications Available from Managing Asbestos in Place: A Building Owner's Guide Asbestos in Your Home Environmental Hazards in Your School: A Resource Handbook OTS Atlas of Dermal Lesions Updated PCB Penalty Policy Copies of these publications and documents are available through the TSCA Hotline, (202) 554-1404, FAX, (202) 554-5603. January 1991 15 ------- Voluntary Audit Program is Announced by EPA EPA has announced a one-time voluntary program that strongly encourages companies to audit their files for studies reportable under sec- tion 8(e) of the Toxic Substances Control Act (TSCA). The TSCA Section 8(e) Compliance Audit Program (CAP) sets guidelines for EPA's enforce- ment response, which allows companies to assess liability before deciding to participate. A 90-day registration period for the program was announced in a February 1, 1991, Federal Register notice. Further information regarding the program and registration is available from the TSCA Assistance Information Service (TSCA Hotline). See page 32 for information about con- tacting the hotline. TSCA Section 8(e) Notices Section 8(e) of the Toxic Substances Control Act (TSCA) requires anyone who manufactures, imports, processes, or distributes a chemical substance or mix- ture that presents a substantial risk of injury to health or the environment to notify EPA within 15 working days from the time they come into possession or know of it. The Office of Toxic Substances (OTS) reviews initial section 8(e) notices. These reviews, or "status reports," are publicly available and typically contain a description and preliminary evaluation of the sub- mitted information, a statement regarding produc- tion and uses of the subject chemical(s), and recom- mendations for appropriate OTS follow-up actions or activities. Below is a list of initial TSCA section 8(e) notices received between November 1, 1989, and September 30,1990. In the list, "S" indicates that a sanitized, or nonconfidential, version of the docu- ment is available, and "P" indicates that a portion of the submission is protected under the Privacy Act. TSCA Section 8(e) Notices Log No. 8EHQ- Chemical Name CAS No. Type of Information 1189-0839 1189-0840 S 1189-0841 1189-0842 S 1189-0843 S 1189-0844 S Oxyalkylated Linear Alcohol- Carboxylic acid adduct Hydrazide, Oxo-(Substituted Amino) Acetic Acid Phosphinate, Tetra-N- Butylphosphonium Phenyl- Benzdioxolcarbonitrile, Substituted Halogenated Benzoyl Urea Alkyl Halide unknown Allergenicity (Animal) confidential Subchronic Toxicity (Animal) unknown Neurotoxicity (Animal) Acute Toxicity (Animal) confidential Reproductive Toxicity/Terato. (Animal) confidential Neurotoxicity (Animal) Subchronic Toxicity (Animal) confidential Reproductive Toxicity/Terato. (Animal) 16 January 1991 ------- TSCA Section 8(e) Notices, Continued Log No. 8EHQ- Chemical Name CAS No. Type of Information 1189-0845 1189-0846 1189-0847 1189-0848 S 1289-0849 S 1289-0850 1289-0851 S 1289-0852 S 1289-0853 S 1289-0854 S 1289-0855 1289-0856 1289-0857 S 1289-0858 S 1289-0859 0190-0860 S 0190-0861 S 0190-0862 S Hydrazine, (4-(Methylbutoxy)- Phenyl)-, Monohydrochloride Cumene Spiro[1,3-Dioxane-5,3'-[7] Oxabicycto[4.l .0]Heptane], 2-(7-Oxabicyclo [4.1.0] Hept-3-YL)- Spiro [1,3-Dioxane-5,3'-[7] Oxabicyclo[4.1 .0]Heptane], 2-(7-OxAbicyclo [4.1.0]Hept-3- YL)-, Homopolymer Hydrazine, Substituted Substituted Organic Ammonium Chloride 0-Ethyl-0-Methylethyl-0- [2-(1,1-Dimethylethyl)- Pyrimidin- 5-YL]-Thionophosphorous Acid Ester Ether, Diaryl Benzenamine, 4,4'-[1,4- Phenylenebis(1- Methylethylidene)]Bis- Benzenamine, 4,4'-[1,4- Phenylenebis(l-Methylethylidene) ]Bis[2,6-Dimethyl- Amide, Heterocyclic Amine, Heterocyclic Methanone, (2-Hydroxy-4- Methoxyphenyl)Phenyl- Vinyi Fluoride Carbazole, Indolo- Ketone, Alkyl Ethene, Bromotrifluoro- Ethene, Bromotrifluoro-, Homopolymer, Pyrolysis Products Of Ethene, Bromotrifluoro-, Homopolymer Lactone, Substituted Polycyclic Nitrobenzene, Alkoxy Aryloxy unknown 98-82-8 3388-03-2 26616-47-7 confidential confidential unknown confidential 2716-10-1 2716-12-3 confidential confidential 131-57-7 75-02-5 confidential confidential 598-73-2 none 55157-25-0 confidential confidential Acute Toxicity (Animal) Subacute Toxicity (Animal) Allergenicity (Animal) Neurotoxicity (Animal) Subchronic Toxicity (Animal) Oncogenicity (Animal) Chronic Toxicity (Animal) Clastogenicity (In Vitro) Neurotoxicity (Animal) Acute Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Acute Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/ Terato. (Animal) Acute Toxicity (Animal) Allergenicity (Animal) DNA Damage/Repair Mutagenicity (In Vitro) Reproductive Toxicity/Terato. (Animal) Subchronic Toxicity (Animal) Oncogenicity (Animal) Chronic Toxicity (Animal) Human Exposure (Monitoring) Acute Toxicity (Animal) Oncogenicity (Animal) Mutagenicity (In Vitro) Reproductive Toxicity/Terato. (Animal) Chronic Toxicity (Animal) Acute Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Continued on next page January 1991 17 ------- TSCA Section 8(e) Notices, Continued Log No. 8EHQ- Chemical Name CAS No. Type of Information 0190-0863 Benzidine, 3,3'-Dichloro- 91-94-1 Oncogenicity (Human) Benzidine 92-87-5 Chronic Toxicity (Human) O-Dianisidine 119-90-4 Epidemiology/Clinical O-Tolidine 119-93-7 Human Exposure (Monitoring) Benzidine, 3,3'-Dichloro-, 612-83-9 Dihydrochloride 0190-0864 Aniline 62-53-3 Oncogenicity (Human) O-Toluidine 95-53-4 Chronic Toxicity (Human) Epidemiology/Clinical 0190-0865 S Acetanilide, Heterocyclic confidential Reproductive Toxicity/Terato. Substituted (Animal) 0190-0866 S 2-Propenoic Acid, Polymer With unknown Subchronic Toxicity (Animal) Sodium Phosphinate, Sodium Salt 2-Propenoic Acid, Polymer With 71050-62-9 Sodium Phosphinate, 0190-0867 Phenol, 2-[(Ethylamino) 71130-60-4 Neurotoxicity (Animal) Methyl]-4-Nitro- Acute Toxicity (Animal) 0190-0868 S Imidate, N-Arylcyclic confidential Reproductive Toxicity/Terato. (Animal) 0190-0869 S Acetanilide, Heterocyclic confidential Reproductive Toxicity/Terato. Substituted (Animal) 0190-0870 S Imidate (I), N-Aryl-Cyclic confidential Reproductive Toxicity/Terato. (Animal) 0190-0871 S Alkyl Amine, Ethoxylated confidential Reproductive Toxicity/Terato. (Animal) 0290-0872 S Polycyclic Dione, Substituted confidential Reproductive Toxicity/Terato. (Animal) 0290-0873 S Amine, Aromatic confidential Oncogenicity (Animal) Chronic Toxicity (Animal) 0290-0G74 S Guanidinium Aryl Sulfonate, confidential Reproductive Toxicity/Terato. Substituted (Animal) 0290-0875 S Phosphate Ester Hydraulic Fluid, confidential Reproductive Toxicity/Terato. Mile Phosphate Ester-Based none (Animal) 0290-0876 Benzene, 1,1'-Methylenebis 101-68-8 Allergenicity (Animal) [4-lsocyanato- Immunotoxicity (Human) 0290-0877 Phosphonium, Tetrakis 124-64-1 Reproductive Toxicity/Terato. (Hydroxymethyl)-, Chloride (Animal) Phosphonium, Tetrakis 55566-30-8 (Hydroxymethyl)-, Sulfate (2:1) (Salt) 0290-0878 2-Propanamine Benzenamine, 75-31-0 Reproductive Toxicity/Terato. N,N-Diethyl-Benzenamine, N-(1- 91-66-7 (Animal) Methylethyl)- 768-52-5 Phosphorochloridothioic Acid, 2524-03-0 O.O-Dimethyl Ester 0290-0879 S Aryl Diester, Halo Alkyl confidential Reproductive Toxicity/Terato. Substituted (Animal) 0290-0880 S Diisocyanate, Carbocyclic confidential Subacute Toxicity (Animal) Diisocyanate Polymer, Substituted confidential Acetic Acid, Butyl Ester 123-86-4 0290-0881 S Hexanedione, Cyclo- confidential Oncogenicity (Animal) Reproductive Toxicity/Terato. (Animal) Subchronic Toxicity (Animal) Chronic Toxicity (Animal) 18 January 1991 ------- TSCA Section 8(e) Notices, Continued Log No. 8EHQ- Chemical Name CAS No. Type of Information 0290-0882 0290-0883 S 0290-0884 0290-0885 0290-0886 0290-0887 S 0290-0888 S 0290-0889 S 0290-0890 S 0290-0891 S 0290-0892 0290-0893 0290-0894 0390-0895 S 0390-0896 S 0390-0897 S 0390-0898 0390-0899 0390-0900 0390-0901 0390-0902 0390-0903 S 0390-0904 Diberizofurans, Chlorinated Dioxins, Chlorinated Petroleum Refining Process Reformer Spray Tur Ether, Diaryl Isopropanol C. I. Reactive Black 5 Oil (Petroleum), Refining Process Acetic Acid Ester, Substituted Ether, Diaryl Acetanilide, Substituted Acetophenone Oxime Ether, Aryl Alkyl 1-Propene, 2,3-Dichloro- Carbon Oxide Sulfide, (COS) Phosphorochloridothioic Acid, 0,0-Dimethyl Ester Propane, 1,1,2,2,3-Pentachloro- Benzene, (1,1-Dimethylethyl) Ethyl- Benzoic Acid, 4-Methoxy-, 4-Pentylphenyl Ester Py rid inecarboxy late Acetanilide, Substituted, (I) Acetanilide, Substituted, (II) Benzenamine, 4,4'-(1,3- Phenylenebis(oxy)Bis- Silicate, Tetramethyl Ammonium Propane, 2-Methoxy-2-Methyl- 1,3-Butadiene 2-Butene, 2-Methyl- 1-Butene, 2-Methyl- Isoamylene 1,3-Butadiene Naphthalenol Aromatic Azo Dye Of Aromatic Compounds Carbon Disulfide none none none none confidential 67-63-0 17095-24-8 none confidential confidential confidential confidential confidential 78-88-6 463-58-1 2524-03-0 16714-68-4 37871-12-8 38444-13-2 confidential confidential confidential 2479-46-1 56982-91-3 1634-04-4 106-99-0 513-35-9 563-46-2 26760-64-5 106-99-0 confidential 75-15-0 Human Exposure (Monitoring) Env. Occurrence/Release/Fate Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Subacute Toxicity (Animal) Acute Toxicity (Human) Human Exposure (Accidental) Allergenicity (Human) Oncogenicity (Human) Chronic Toxicity (Human) Epidemiology/Clinical Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Mutagenicity (In Vivo) Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Animal) Acute Toxicity (Animal) Allergenicity (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive ToxicityfTerato. (Animal) Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Animal) Acute Toxicity (Animal) Ecotoxicity/Aquatic Toxicity Chronic Toxicity (Animal) Clastogenicity (Animal) Clastogenicity (Animal) Mutagenicity (In Vitro) Clastogenicity (Animal) Reproductive Toxicity/Terato. (Animal) Continued on next page January 1991 19 ------- Log No. 8EHQ- TSCA Section 8(e) Notices, Continued Chemical Name CAS No. Type of Information 0390-0905 S 0390-0906 S 0390-0907 S 0390-0908 S 0390-0909 0390-0910 S 0390-0911 S 0390-0912 S 0390-0913 S 0390-0914 S 0390-0915 0390-0916 S 0490-0917 0490-0918 S 0490-0919 S 0490-0920 S 0490-0921 S 0490-0922 S 0490-0923 S 0490-0924 0490-0925 S 0490-0926 S 0490-0927 S Amine, Aromatic Magnaclear W 241 Semicarbazone Phenol, 4,4'-[Oxybis(2,1- Ethanediylthio)]Bis- 1,3-Benzenedimethanamine 1-Hexanol, 2-Ethyl- Isodecanol Isononyl Alcohol Aryl Alkyl Heterocyclic Carboxylate Urea, 1-Methoxy-1-Methyl- 3-[4-(3,4-Dihydro-2-Methoxy-2,4, 4-Trimethyl-7-Benzopyranyloxy) Phenyl]- Aluminum Production Process Semicarbazone Methyl Methacrylate Ethyl Acrylate Amide, Heterocyclic Hydrazide, Substituted Carbonothioic Alkenoyl Disubstituted Cycloalkane Phenol, 4,4'-[Methylenebls(Oxy- 2,1 -EthanediylthioJJBis- Hydrocarbon, Chlorinated Acetanilide, Substituted, (III) Formaldehyde Thioester, Heterocyclic Ether, Diaryl, (IV) Amine, Aryl confidential confidential confidential confidential 1477-55-0 104-76-7 25339-17-7 68515-81-1 confidential unknown none confidential 80-62-6 140-88-5 confidential confidential confidential confidential confidential confidential 50-00-0 confidential confidential confidential Acute Toxicity (Human) Epidemiology/Clinical Human Exposure (Accidental) Env. Occurrence/Release/Fate Ecotoxicity/Aquatic Toxicity Reproductive Toxicity/Terato. (Animal) Subacute Toxicity (Animal) Ecotoxicity/Aquatic Toxicity Clastogenicity (Animal) Reproductive Toxicity/Terato, (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Animal) Neurotoxicity (Animal) Chronic Toxicity (Animal) Oncogenicity (Human) Chronic Toxicity (Human) Epidemiology/Clinical Mutagenicity (In Vitro) Mutagenicity (In Vivo) Oncogenicity (Human) Chronic Toxicity (Human) Epidemiology/Clinical Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Animal) Acute Toxicity (Animal) Allergenicity (Animal) Acute Toxicity (Animal) Clastogenicity (Animal) Env. Occurrence/Release/Fate Emergency Incident Of Env. Contamination Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Tetro. (Animal) Oncogenicity (Human) Chronic Toxicity (Human) Epidemiology/Clinical Human Exposure (Monitoring) Reproductive Toxicity/Terato. (Animal) Subacute Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) 20 January 1991 ------- TSCA Section 8(e) Notices, Continued Log No. 8EHQ- Chemical Name CAS No. Type of Information 0490-0928 S 0490-0929 S 0490-0930 S 0490-0931 S 0490-0932 0490-0933 0490-0934 S 0490-0935 S 0490-0936 0490-0937 0490-0938 0490-0939 0490-0940 0490-0941 0490-0942 0490-0943 0490-0944 0490-0945 Carboxylic Acid Ester, Heterocyclic Ether, Halogenated Ether, Diaryl, (V) Benzenepropanal, 4-(1,1- Dimethylethyl)-Alpha-Methyl- 2-Propenal, 3-[4-(1,1- Dimethylethyi)Phenyl]-2-Methyi- Sludge, Api Separator Bottom Sludge, Dissolved Air Flotation (DAF) Float Polychlorinated Biphenyls (PCB) Phosphoroamidate Imidazole Derivative L-2-Chloroproprionic Acid, Isobutyl Ester Phosphonic Acid, lNitrilotris(Methylene)]Tri8- Phosphonic Acid, [Nitrilotris(Methylene)]Tris-> Sodium Salt P-T oluene8ulfonamlde O-Toluenesulfonamide Stilbene, Trans- Phosphonic Acid, [1,2- Ethanediylbis[Nitrilobis (Methylene)]Tetrakls- Benzene, 1,3-Dimethyl-, Benzylated Poly(Oxy-1,2-Ethanedlyl), Alpha-(Dodecylphenyl)- Omega-Hydroxy- Butanoic Acid, 1- Cyciohexylethyl Ester Phosphoric Acid, 2,2-Bis (Chioromethyl)-1,3-Propanediyl Tetrakis (2-Chloroethyl) Ester Oxoacetic Acid Homopolymer, Sodium Salt confidential Reproductive Toxicity/Terato. (Animal) confidential Acute Toxicity (Human) Epidemiology/Clinical Human Exposure (Accidental) confidential Mutagenicity (In Vitro) Reproductive Toxicity/Terato. (Animal) Subchronic Toxicity (Animal) Chronic Toxicity (Animal) 80-54-6 Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Animal) 13586-68-0 Subacute Toxicity (Animal) Subchronic Toxicity (Animal) none Mutagenicity (In Vitro) Reproductive Toxicity/Terato. none (Animal) Subchronic Toxicity (Animal) 1336-36-3 Human Exposure (Accidentia!) Human Exposure (Monitoring) Env. Occurrence/Release/Fate Emergency Incident of Env. Contamination confidential Neurotoxicity (Animal) Subacute Toxicity (Animal) confidential Reproductive Toxicity/Terato. (Animal) 83261-15-8 Neurotoxicity (Animal) Subchronic Toxicity (Animal) 6419-19-8 Reproductive Toxicity/Terato. (Animal) 20572-85-2 70-55-3 Reproductive Toxicity/Terato. 88-19-7 (Animal) 103-30-0 Reproductive Toxicity/Terato. (Animal) 1429-50-1 Reproductive Toxicity/Terato. (Animal) 68908-87-2 Reproductive Toxicity/Terato. Terato. (Animal) 9014-92-0 Reproductive Toxicity/Terato. (Animal) 63449-88-7 Reproductive Toxicity/Terato. (Animal) 38051-10-4 Reproductive Toxicity/Terato. (Animal) 70205-95-7 Reproductive Toxicity/Terato. (Animal) Continued on next page January 1991 21 ------- TSCA Section 8(e) Notices, Continued Log No. 8EHQ- Chemical Name CAS No. Type of Information 0490-0946 Glycine, N-(Carboxymethyl)- 142-73-4 Reproductive Toxicity/Terato. (Animal) 0490-0947 Phosphonic Acid, [1-[[(2- Chloroethoxy) (2-Chloroethyl) Phosphinyl]Oxy]Ethyl]-, 1 -[Bis(2- Chloroethoxy)Phosphinyl]Ethyl 2-Chloroethyl Ester 4351-70-6 Reproductive Toxicity/Terato. (Animal) 0490-0948 1,3-lsobenzofurandione, 4,5,6,7-Tetrachloro- 117-08-8 Reproductive Toxicity/Terato. (Animal) 0490-0949 Cyclohexane, 1,1'-(1,1,3- Trimethyl-1,3-Propanediyl)Bis- 38970-72-8 Reproductive Toxicity/Terato. (Animal) 0490-0950 Phosphonic Acid, [[(Phosphonomethyl)lminoJBis[2, l-Ethanediylnitrilobis(Methylene)]] Tetrakis- Phosphonic Acid, [[(Phosphonomethyl)lmino]Bis[2, 1 -Ethanediylnitrilo)Bis (Methylene)]] Tetrakis-, Sodium Salt 15827-60-8 22042-96-2 Reproductive Toxicity/Terato. (Animal) 0490-0951 Phosphonic Acid, [[(Phosphonomethyl)lmino]Bis[2, l-Ethanediylnitrilobis(Methylene)]] Tetrakis- 15827-60-8 Reproductive Toxicity/Terato. (Animal) 0490-0952 S Carbamic Acid Nitrile confidential Oncogenicity (Animal) Chronic Toxicity (Animal) Metabolism/Pharmacokinetics (Animal) 0490-0953 Ethane, 1,1,1-Trichloro- 71-55-6 Human Exposure Ethane, 1,1-Dichioro- 75-34-3 (Monitoring) Ethene, 1,1-Dichloro- 75-35-4 Env. Occurrence/Release/Fate Groundwater contamination 0490-0954 S Vinyl Ether Terminated Ester confidential Neurotoxicity (Animal) Acute Toxicity (Animal) 0490-0955 S Acetanilide, Substituted confidential Reproductive Toxicity/Terato. (Animal) 0490-0956 S Ketone, Diaryl confidential Reproductive Toxicity/Terato. (Animal) 0490-0957 S Pyrimidine, Substituted confidential Neurotoxicity (Animal) Acute Toxicity (Animal) 0490-0958 S Pyrimidine, Substituted confidential Neurotoxicity (Animal) Acute Toxicity (Animal) 0490-0959 S Amine Metal Complex confidential Neurotoxicity (Animal) Acute Toxicity (Animal) 0490-0960 1(H)-1,2,4-Triazole-3- Carboxylate, Ethyl 1-(2,4- Dichlorophenyl)-5- Trichloromethyl- 103112-35-2 Oncogenicity (Animal) Mutagenicity (In Vitro) Chronic Toxicity (Animal) 0490-0961 S Amino Acid (I) confidential Reproductive Toxicity/Terato. (Animal) 0490-0962 Diarylide Pigments none Human Exposure (Monitoring) Benzidine, 3,3'-Dichloro- 91-94-1 Production/Use/Process 0490-0963 Phosphorous Acid, 25550-98-5 Neurotoxicity (Animal) Diisodecyl Phenyl Ester 22 January 1991 ------- TSCA Section 8(e) Notices, Continued Log No. 8EHQ- Chemical Name CAS No. Type of Information 0590-0964 Cyclic 1,4-Perfluorobutane Disulfonimide, Lithium Salt unknown Neurotoxicity (Animal) Acute Toxicity (Animal) 0590-0965 Benzene, C10-16-Alkyl Derivs. 68648-87-3 Reproductive Toxicity/Terato. (Animal) 0590-0966 1,4-Benzenediamine, N- (1,3-Dimethylbutyl)-N'-Phenyl- 793-24-8 Reproductive Toxicity/Terato. (Animal) 0590-0967 1,2-Benzenedicarboxylic Acid, 4,4'-Carbonylbis-, AR.AR'-Diethyl Ester, Compd. With 1,3-Benzenediamine 65701-07-7 Reproductive Toxicity/Terato. (Animal) 0590-0968 Urea, N-(4-Chlorophenyl)-N'-(3,4- Dichlorophenyl)- 101-20-2 Reproductive Toxicity/Terato. (Animal) Chronic Toxicity (Animal) 0590-0969 Benzene, C14-30-Alkyl Derivs. 68855-24-3 Reproductive Toxicity/Terato. (Animal) 0590-0970 Benzene, C10-16-Alkyl Derivs. 68648-87-3 Reproductive Toxicity/Terato. (Animal) 0590-0971 1,2-Benzenedicarboxylic Acid, Dibutyl Ester 84-74-2 Reproductive Toxicity/Terato. (Animal) 0590-0972 Benzene, 1,2-Dichloro-4-Nitro- 99-54-7 Reproductive Toxicity/Terato. (Animal) 0590-0973 Benzene, 1-Chloro-2-Nitro- 88-73-3 Reproductive Toxicity/Terato. (Animal) 0590-0974 1 -Piperidinecarboxaldehyde 2591-86-8 Reproductive Toxicity/Terato. (Animal) 0590-0975 Phosphoric Acid, Triphenyl Ester Phosphoric Acid, (1-Methyl- 1-Phenylethyl)Phenyl Diphenyl Ester Phosphoric Acid, Nonylphenyl Diphenyl Ester 115-86-6 34364-42-6 38638-05-0 Reproductive Toxicity/Terato. (Animal) 0590-0976 Phosphoric Acid, Triphenyl Ester Phosphoric Acid, (1 -Methyl-1 -Phenylethyl) Phenyl Diphenyl Ester Phosphoric Acid, Nonylphenyl Diphenyl Ester 115-86-6 34364-42-6 38638-05-0 Reproductive Toxicity/Terato. (Animal) 0590-0977 1,4-Benzenediamine, N,N'-Bis{1,4- Dimethylpentyl)- 3081-14-9 Reproductive Toxicity/Terato. (Animal) 0590-0978 Phenol, 2-Nitro- 88-75-5 Reproductive Toxicity/Terato. (Animal) 0590-0979 1,6-Hexanediamine 124-09-4 Reproductive Toxicity/Terato. (Animal) 0590-0980 Benzene, 1-Chloro-4-Nitro- 100-00-5 Reproductive Toxicity/Terato. (Animal) 0590-0981 Formamide, N,N-Dimethyl- 68-12-2 Mutagenicity (In Vivo) Acetamlde, N,N-Dimethyl- 127-19-5 Reproductive Toxicity/Terato. (Animal) 0590-0982 Hexanedioic Acid, Dlnonyl Ester Hexanedioic Acid, Diheptyl Ester Hexanedioic Acid, Di-C7-9-Branched and Linear Alkyl Esters 151-32-6 14697-48-4 68515-75-3 Reproductive Toxicity/Terato. (Animal) Continued on next page January 1991 23 ------- TSCA Section 8(e) Notices, Continued Log No. 8EHQ- Chemicat Name CAS No. Type of Information 0590-0983 0590-0984 0590-0985 0590-0986 S 0590-0987 S 0590-0988 S 0590-0989 S 0590-0990 S 0590-0991 S 0590-0992 S 0590-0993 S 0590-0994 0590-0995 S 0590-0996 0590-0997 S 0590-0998 S 0690-0999 0690-1000 S 0590-1001 S 0690-1002 Terphenyl Terphenyl, Hydrogenated Benzene, (Phenylethyl)- Berizene, Ethyl (Phenylethyl)-Benzene, Ethyl (Phenylethyl)-, Mono-AR-Ethyl Deriv. Naphthalene, 1,2,3,4- Tetrahydro-, C1-4-Alkyl Derivs. 1-Decene, Polymer with 1-Octene, Hydrogenated Siloxanes and Silicones, Di-Me, Reaction Products with Silica Sulfonamide (#1), Aromatic Sulfanamide (#3), Aromatic Sulfonamide (<*2), Aromatic Amine, Heterocyclic Amine, Diaryl lridate(3-), Hexachloro-, Tripotassium, (OC-6-11)- Pyridazine, Substituted Phosphoric Acid, Alkyl Latex Effluent Tert-Dodecane thiol Amide, Haloalkyl Heteroaromatic 2,4,8,10-T etraoxa-3,9- Diphosphaspiro[5.5]Undecane, 3,9-Bis{0 ctadecyloxy)- Dtphenyl Ether, Substituted Nitrobenzene, Aryloxy Substituted Methyl Methacrylate 1 H-Pyrrole-2,5-Dione, 1-Phenyl- Halogenated Alkyl Ester Ethanol, 2-[2-(2- Methoxyethoxy)Ethoxy]- 26140-60-3 61788-32-7 38888-98-1 64800-83-5 68398-19-6 68412-24-8 66070-54-0 67762-90-7 confidential confidential confidential confidential confidential 14024-41-0 confidential confidential none 25103-58-6 confidential 3606-34-6 confidential confidential 80-62-6 941-69-5 confidential 112-35-6 Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Acute Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Human) Acute Toxicity (Human) Acute Toxicity (Animal) Epidemiology/Clinical Allergenicity (Human) Reproductive Toxicity/Terato. (Animal) Oncogenicity (Animal) Chronic Toxicity (Animal) Ecotoxicity/Aquatic Toxicity Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Subacute Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Animal) Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Animal) Subchronic Toxicity (Animal) 24 January 1991 ------- TSCA Section 8(e) Notices, Continued Log No. 8EHQ- Chemical Name CAS No. Type of Information 0690-1003 0690-1004 S 0690-1005 S 0690-1006 S 0690-1007 0690-1008 0690-1009 0690-1010 S 0690-1011 S 0690-1012 S 0690-1013 S 0690-1014 S 0690-1015 0690-1016 S 0690-1017 0690-1018 0690-1019 0690-1020 0790-1021 0790-1022 S 0790-1023 S 0790-1024 0790-1025 S 0790-1026 S 0790-1027 Isoamylene Oxide Ketoxime (I), Aliphatic Ketoxime (II), Aliphatic Amide, Substituted Organic Phosphoric Acid Tributyl Ester Glutardialdehyde Silane, Dimethoxymethyl- Nitrobenzene (II), Alkoxy Aryloxy Carboxylic Acid Ester, Aryloxy-Substituted Alkyl Amide, Aryl-Substituted Amino Sulfone, Aryl Methyl Benzene, Halogenated Substituted Epikote 1071 Epon HPT Resin 1071 Quinoline, Substituted Crotonaldehyde Silicon Carbide Fibers Asbestos Alumina Whiskers XB-4458 Octanoic Acid, Zinc Salt 1 H-lmidazole, 1-Methyl- Benzene, 1-Chloro-2- (Chloromethyl)- Benzenediazonium, 3- Methyl-4-{1 -Pyrrolidinyl)-, Trlchlorozincate(l-) Hydrocarbyl Sulfide, Substituted 1H-Pyrrole-2,5-Dione, 1.1*- (4-Methyl-1,3-Phenylene)Bis- 1 H-lsoindole-1,3-(2H)- Dione, 2-Butyl-5-Nitro- Amine, Haloalkyl Benzenamine, Aryloxy Substituted Phenol, 2,6-Dimethyl- 5076-19-7 confidential confidential confidential 126-73-8 111-30-8 16881-77-9 confidential confidential confidential confidential confidential 103490-06-8 103490-06-8 confidential 4170-30-3 409-21-2 1332-21-4 1344-28-1 unknown 557-09-5 616-47-7 611-19-8 52572-38-0 confidential 6422-83-9 54395-37-8 confidential confidential 576-26-1 Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Animal) Acute Toxicity (Animal) Subacute Toxicity (Animal) Neurotoxicity (Animal) Acute Toxicity (Animal) Neurotoxicity (Animal) Acute Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Animal) Subacute Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Mutagenicity (In Vitro) Acute Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Mutagenicity (In Vitro) Clastogenicity (Animal) Mutagenicity (In Vitro) Acute Toxicity (Animal) Ecotoxicity/Aquatic Toxicity Cell Transformation (In Vitro) Human Exposure (Monitoring) Subacute Toxicity (Animal) Subacute Toxicity (Animal) Acute Toxicity (Animal) Subacute Toxicity (Animal) Acute Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Reproductive Toxicity/Terato. (Animal) Subacute Toxicity (Animal) Continued on next page January 1991 25 ------- TSCA Section 8(e) Notices, Continued Log No. 8EHQ- Chemical Name CAS No. Type of Information 0790-1028 S 0790-1029 0790-1030 0790-1031 S 0790-1032 0790-1033 0790-1034 0790-1035 0790-1036 S 0790-1037 S 0890-1038 0890-1039 S 0890-1040 0890-1041 0890-1042 0890-1043 0890-1044 S 0890-1045 0890-1046 Bis(Substituted Phenyl) Substituted Amino Heteromonocycle Rare Earth Y (Rey) Crystals Aluminum Oxide, Alpha- Monohydrate C. I. Disperse Blue 79:1 (Purified Presscake) Pyridopyridimine, Substituted Misc. Chemicals Acetic Acid, [[[3,5-Bis(1,1- Dimethylethyl)-4-Hydroxphenyl] Methyl]Thio]-, C10-14-lsoalkyl Esters DDT Benzene, 1,1'-(2,2- Dichloroethylidene)Bis [4-Chloro-Benzene, 1,1 '-(2,2- Dichloroethylidene)Bis[4-Ethyl- 2-Butenoic Acid, 2-(1- Methylheptyi)-4,6-Dinitrophenyl Ester, (E)- Zinc, Bis(1-Hydroxy-2(1H)- Pyridinethionato-0,S)-,(T-4)- Quinazoline (IV), Substituted Cyclohexane, Substituted Dibenzofurans, Chlorinated Dioxins, Chlorinated Sulfurized Compounds, Mixture of 1,2,4-Thiadiazole, Poly(3,5-Dithio- 2-Hexanol, 2-[(1,1- Dimethylethyl)Azo]-5-Methyl- Hydrazine, (1,1- Dimethylethyl)-, Monohydrochloride Iron Chloride, (FECL3) Ethanol, 2-(Diethylamino)- Tribromomethyl Substituted Heterocycle Zinc, Bis (Dimethylcarbamodithioato- S,S>, (T-4)- Ethane, 1,1-Dichloro-1, 2-Difluoro- confidential unknown 1318-23-6 3618-72-2 confidential none 118832-72-7 50-29-3 72-54-8 72-56-0 131-72-6 13463-41-7 confidential confidential none none confidential unknown 64819-51-8 7400-27-3 7705-08-0 100-37-8 confidential 137-30-4 1842-05-3 Neurotoxicity (Animal) Subacute Toxicity (Animal) Oncogenicity (Animal) Chronic Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Acute Toxicity (Animal) Ecotoxicity/Aquatic Toxicity Env. Occurrence/Release/Fate Emergency Incident of Env. Contamination Subacute Toxicity (Animal) Allergenicity (Animal) Oncogenicity (Human) Chronic Toxicity (Human) Epidemiology/Clinical Acute Toxicity (Animal) Acute Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Subacute Toxicity (Animal) Human Exposure (Monitoring) Env. Occurrence/Release/Fate Allergenicity (Human) Acute Toxicity (Animal) Neurotoxicity (Animal) Subacute Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Acute Toxicity (Human) Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Animal) Chronic Toxicity (Animal) Mutagenicity (In Vitro) Acute Toxicity (Animal) Reproductive Toxicity/Terato. Terato. (Animal) Subacute Toxicity (Animal) 26 January 1991 ------- TSCA Section 8(e) Notices, Continued Log No. 8EHQ- Chemical Name CAS No. Type of Information 0890-1047 0890-1048 S 0890-1049 S 0890-1050 S 0890-1051 S 0890-1052 S 0890-1053 0890-1054 S 0890-1055 S 0890-1056 S 0990-1057 0990-1058 S 0990-1059 S 0990-1060 S 0990-1061 0990-1062 0990-1063 0990-1064 0990-1065 0990-1066 S 0990-1067 0990-1068 2,7-Dioxa-3,6-Disilaoctane, 3,3,6,6-Tetramethoxy- Alkenoic Acid, Substituted-, Alkyl Ester Vanadium Compound, Inorganic Substituted Phenoxyether Derivative of a Polyheterocycle 1,5-Naphthalenedisulfonic Acid, 2-[[4,5-Dihydro-3- Methyl-5-OXO-1-l4[|2- (Sulfooxy)Ethyl]Sulfonyl] Phenyl]-1 H-Pyrazoi-4-YL]Azo]-, Potassium Sodium Salt Halophenyl Substituted Monoheterocycle Ethylene Oxide Amine Polymer, Substituted Oiphenyl Ether, Substituted Diphenyl Ether, Substituted Phenol, Isopropylated, Phosphate (3:1) Alpha-Cyanocarbocyclic Carboxylate Alkaline Oxidizer Amine, Haloalkyl, 1,4-Hexadiene 3-Pentanone, 2,4-Dimethyl- 2-Butanone, Oxime Ethanol, 2,2*-[1,2- Ethanediylbis(Oxy)]Bis 2-Butanol, 2-[(1,1- Dimethylethyl)Azo)- Allyloxy Ketal Allyloxy Precursor, Unketalized Silane, (3-Chloropropyl) Trimethoxy- 4-(Dimethylamino) Benzenediazonium-5- Sulfosallcylate 18406-41-2 confidential confidential confidential 85940-63-2 confidential 75-21-8 confidential confidential confidential 68937-41-7 confidential confidential confidential 592-45-0 565-80-0 96-29-7 112-27-6 57910-79-9 confidential confidential 2530-87-2 unknown Acute Toxicity (Animal) Acute Toxicity (Animal) Subchronic Toxicity (Animal) Oncogenicity (Animal) Chronic Toxicity (Animal) Mutagenicity (In Vitro) Clastogenicity (In Vitro) DNA Damage/Repair Neurotoxicity (Animal) Acute Toxicity (Animal) Oncogenicity (Human) Chronic Toxicity (Animal) Epidemiology/Clinical Human Exposure (Monitoring) Acute Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Subacute Toxicity (Animal) Subacute Toxicity (Animal) Chronic Toxicity (Animal) Neurotoxicity (Animal) Acute Toxicity (Animal) Acute Toxicity (Animal) Acute Toxicity (Animal) Acute Toxicity (Animal) Acute Toxicity (Animal) Subacute Toxicity (Animal) Clastogenicity (Animal) Acute Toxicity (Animal) Subacute Toxicity (Animal) Allergenicity (Animal) Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Animal) Subchronic Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Human) Epidemiology/Clinical Human Exposure (Accidental) Mutagenicity (In Vitro) Mutagenicity (In Vitro) Acute Toxicity (Animal) Continued on next page January 1991 27 ------- TSCA Section 8(e) Notices, Continued Log No. 8EHQ- Chemical Name CAS No. Type of Information 0990-1069 0990-1070 S 0990-1071 0990-1072 0990-1073 S 0990-1074 0990-1075 S 0990-1076 S 0990-1077 0990-1078 0990-1079 S 0990-1080 S 0990-1081 0990-1082 0990-1083 S 0990-1084 Condensate of Aniline, O-Toluidine and Terephthalaldehyde, Reaction Product with Mateic Anhydride Nitrobenzene, Substituted Lead Tin Polybrominated Biphenyls (PBB) Benzene, 1,1'-Oxybis-, Octabromo Deriv. Benzenamine {II), Aryloxy Substituted Resorcinol Diphosphate Propanoic Acid Ester, Aryl Organic Alcohol, Substituted Organic Ester, Substituted Amides, from Diethylenetrlamine and Hydrogenated Tallow Benzene Cutting Fluid Oxadiazole, Substituted Aniline 0-To(uidine 2,5-Xylidine Aniline, 2,4-Dinitro- Aniline, P-Nitro- Anfline, P-Dodecyl- Aniline, P-Butyl P-Toluidine M-Toluidlna 1-Butanamine, N-Butyl- O-Tolidine P-Cresidine Xylidine (Mixed) Acetophenone Oxime, O- (1,3-Dioxolan-2-YL-Methyl)-2,2, 2-T rifluoro-4'-Chloro- Styrene, Acetoxy- Quinazolines Quinolines Silacyciobutane 129217-90-9 confidential 7439-92-1 7440-31-5 unknown confidential unknown confidential confidential confidential 68920-82-1 71-43-2 none confidential 62-53-3 95-53-4 95-78-3 97-02-9 100-01-6 104-42-7 104-13-2 106-49-0 108-44-1 111-92-2 119-93-7 120-71-8 1300-73-8 88485-37-4 2628-16-2 confidential confidential 287-29-6 Allergenicity (Animal) Subacute Toxicity (Animal) Acute Toxicity (Human) Epidemiology/Clinical Chronic Toxicity (Human) E pidemiology/Cli nical Reproductive Toxicity/Terato. (Animal) Subchronic Toxicity (Animal) Reproductive Toxicity/Terato. (Animal) Neurotoxicity (Animal) Acute Toxicity (Animal) Human Exposure (Monitoring) Groundwater Contamination Env. Occurrence/Release/Fate Acute Toxicity (Human) Epidemiology/Clinical Human Exposure (Monitoring) Mutagenicity (In Vitro) Clastogenicity (In Vitro) Epidemiology/Clinical Oncogenicity (Human) Chronic Toxicity (Human) Subacute Toxicity (Animal) Allergenicity (Animal) Ecotoxiclty/Aquatic Toxicity Acute Toxicity (Animal) 28 January 1991 ------- FYI Submissions For Your Information (FYI) submissions are voluntary submissions that cover a wide variety of information and may include data on chemical tox- icity and exposure, epidemiology, monitoring, and environmental fate FYls are submitted by chemical manufacturers, processors, federal, state, or local agencies, foreign governments, academic institu- tions, public interest and environmental groups, and the general public The FYI classification system was established by the Office of Toxic Substances to distinguish such submissions from notices submitted formally to EPA under section 8(e) of TSCA Listed below are the initial FYI submissions received between November 1, 1989, and September 30,1990 In the list, "S" indicates that a sanitized, or nonconfidential, version of the document is available, and "P" indicates that a portion of the submission is protected under the Privacy Act FYI Submissions FYI No Chemical Name CAS No. Type of Information OTS-1189-0724S OTS-1189-0725 OTS-1289-0726S OTS 1289-0727 OTS 1289-0728 OTS-1289-0729 OTS-1289-0730 AX-0190-0731 OTS-01900732 AX-0190-0733 AX-0190-0734 OTS-0190-0735 OTS-0190-0736S OTS-0290-0737 OTS-O290-0738 OTS-0290-0739S OTS-0290-0740 OTS-0290-0741 OTS-0290-0742 OTS-0290-0743 Benzenamine 4-(2 6-DiphenyM- Pyridinyl)- N N Dimethyl 2 Butyne 1 1 1 4 4 4-Hexafluoro- Expen mental Pesticide Benzene Chlorinated Dibenzodloxlns Chromic Acid (HjCraOr) Disodium Salt Misc chemicals used In centrifuge resin systems Hexanedioic Acid bis(2 Ethylhexyl) Ester Lubncating Oil Additive Commercial Hexane Commercial Hexane Metol Phenidone Paper Coating Carbonic Acid Disodium Salt Compd with Hydrogen Peroxide (H202) (2 3) Epon Curing Agent HPT 1061M Confidential Benzene (1 1 Dimethylethyl)ethyl Sodium Fiuonde Pyridine Pentachloro- Pyndine 2 3 5 6-Tetrachloro- Miscsllaneous Chemicals 29312 59-2 692-50-2 none 71-43-2 none 10588-01 9 none 103-23-1 none none none 55-55-0 92-43-3 unknown 15830-89-4 2716-10-1 unknown 37871 12-8 7681-49-4 2176-62 7 2402 79-1 none Mutagenicity (In Vitro) Acute Toxicity (Animal) Mutagenicity (In Vitro) Developmental Toxicity (In Vitro) Human Exposure (Monitonng) Env Occurrence/Release/Fate Env Occurrence/Release/Fate Subchronic Toxicity (Animal) Epidemiology Oncogenicity (Human) Subchronic Toxicity (Animal) Guinea Pig Dermal Sensitization Acute Toxicity (Animal) Reproductive Toxicity/Terato (Animal) Reproductive Toxicity/Terato (Animal) Acute Toxicity (Animal) Subacute Toxicity (Animal) Acute Toxicity (Animal) Acute Toxicity (Animal) Subchronic Toxicity (Animal) Altergemcity (Animal) Acute Toxicity (Animal) Chronic Toxicity (Animal) Ecotoxicity/Aquatic Toxicity Oncogenicity (Human) Epidemiology/Clinical Continued on next page January 1991 29 ------- FYI Submissions, Continued FYI No Chemical Name CAS No Type of Information OTS-0290-0744S Calcium Petroleum Sulfonate unknown Allergemcity (Animal) OTS-0390-0745 Fiber Glass none Epidemiology/Clinical Mineral Wool none OTS-0390-0746S Amide unknown Allergemcity (Animal) OTS-0390-0747 Commercial Hexane none Clastogemcity (Animal) OTS-0390-0748 Commercial Hexane none Reproductive Toxicity/ Terato (Animal) OTS-0390-0749 Nickel Oxide Catalysts none Mutagenicity (In Vitro) OTS-0390-0750 formamide N N Dimethyl 68-12 2 Subchronic Toxicity (Animal) OTS-0390-0751 Lubricating Oil Additive none Allergemcity (Animal) OTS-0390-0752S Alkoxysilane Polymer none Acute Toxicity (Animal) Polyurethane Based Paint none AX-0390-0753 Paint Products none Human Exposure (Product Mercury 7439-97-6 Contamination) OTS-0490-0754 Phenol Dodecyl Sulfurized 68784-26-9 Reproductive Toxicity/Terato Carbonates Calcium Salts (Animal) Overbased OTS-0490-0755 Tetrafluoroethene polymers none Human Exposure (Product Contamination) OT S-0490-0756 Brominated Flame Retardants none Mutagenicity Reproductive Toxicity/Terato (Animal) Subacute Toxicity (Animal) OTS-0490-0757S Unregistered Pesticide unknown Reproductive Toxicity/Terato (Animal) OTS 0490 0758S Substituted Triazole/Substituted none Acute Toxicity (Animal) Piperidine Mixture OTS-0590-0759S Oxirane 75-21 8 Product Composition/Chemical Identity OTS-0590 0760 Halothane unknown Metabolism/Pharmacokinetics (Animal) OTS-0590-0761 Hydrochloric Acid 7647-01-0 Env Occurrence/Release/Fate OTS 0590 0762 Quartz (SiOj) 14808 60-7 Epidemiology/Clinical OTS 0590-0763 2 Butanone Oxime 96-29 7 Reproductive Toxicity/Terato (Animal) OTS-0590 0764 Benzene Ethenyl 100-42 5 Subacute Toxicity (Animal) Ototoxicity (Animal) OTS-0590-0765 Aragonite unknown Human Exposure (Product Contamination) OTS 0690-0766S Alkenoyl Oisubstituted unknown Mutagenicity (In Vitro) Cycloalkane OTS-0690-0767 Acetic Acid Mercury(2+) Salt 1600-27 7 Reproductive Toxicity/Terato (Human) Mercury 7439 97-6 Reproductive Toxicity/Terato (Animal) OTS-0690O768S Inorganic Vanadium Compound unknown Subchronic Toxicity (Animal) OTS 0690 0769 Selexol Solvent 24991 55-7 Acute Toxicity (Animal) Subacute Toxicity (Animal) OTS-0690-0770S EmulsionlBased Anionic and none Ecotoxicity/Aquatic Toxicity Nonionic Polymers OTS 0690 0771 1 Nonanamine 112 20 9 Acute Toxicity (Animal) Skin Corrosivity Test OTS-0790-0772 Dibasic Ester Mixture none Human Exposure (Product Contamination) OTS-0790-0773 Lignosulfonates none Oncogenicity (Animal) Chronic Toxicity (Animal) 30 January 1991 ------- FYI Submissions, Continued FYI No Chemical Name CAS No Type of Information OTS-0790-0774 OTS-0790-0775 OTS-0790-0776 OTS-0890-0777 OTS-0890-0778 OTS-069(M)779S OTS-0890-0780 OTS-0890-0781 OTS-0890-0782S OTS-0890-0783S OTS-O890-0784 OTS-0890-0785 OTS-0890-0786S OTS-0890-0787 OTS-0890-0788 OTS-0990-0789 OTS-0990-0790 OTS-1090-0791 Glass Fibers Refractory Ceramic Fibers Poly(Oxy 1 2 Ethanediyl) Alpha (Carboxymethyl) Omega Hydroxy C12 15-Alkyl Ethers Sodium Salts Methane Chloromethoxy Methane Oxybis[Chloro- Phosphonc Acid Tnbutyl Ester Cutting Fluids Mixed Triaryl Phosphate Oxirane ERL 1914-4 Resin Substituted Aromatic Ketone Mixture Yeast 2 Propanol none HCFC 225 Isomer Mixture M85 Fuel Methanol Indian Phthalo Blue Crude 2 Pentenenitnle Carbon Disulfide none none 70632-06-3 107-30-2 542-88-1 126-73-8 none unknown 75-21 8 unknown unknown unknown 67-63-0 none none unknown 67 56-1 unknown 13284-42 9 75-15-0 Acute Toxicity (Animal) Metabolism/Pharmacokinetics Human Exposure (Monitoring) Reproductive Toxicity/ Terato (Animal) Oncogenicity (Human) Epidemiology/Clinical Reproductive Toxicity/Terato (Animal) Epidemiology/Clinical Neurotoxicity (Animal) Acute Toxicity (Animal) Oncogenicity (Human) Epidemiology/Clinical Allergenicity (Animal) Ecotoxicity/Aquatic Toxicity Allergenicity (Human) Chronic Toxicity (Animal) Risk Appraisal Methodology Subacute Toxicity (Animal) Acute Toxicity (Human) Epidemiology/Clinical Acute Toxicity (Human) Absorption Studies Product Composition/Chemical Identity Neurotoxicity (Animal) Acute Toxicity (Animal) Epidemiology/Clinical Availability of 8(e) Notices and FYI Submissions Section 8(e) notices and status reports and FYI submissions are located in the OTS Public Reading Room, Room NE-G004, 401 M Street S W, Washington, D C 20460 Single ^copies of section 8(e) status reports are available from the OTS Environmental Assistance Division, TS-799, EPA, 401 M Street S W, Washington, D C 20460, telephone, (202) 554-1404, FAX, (202) 554-5603 To obtain a copy of a full section 8(e) or FYI submission, write to EPA, Freedom of Information (A-101), Washington, DC 20460 Duplication of the first 166 pages of any document is free At the 167th page, there is a $25 fee and an addi- tional $0 15 charge for each page For example, duplication of a 167-page document will cost $25 15 Would You Like to Receive the Chemicals-in-Progress Bulletin'' The Chemicals-in-Progress Bulletin is pub- lished by EPA's Office of Toxic Substances To receive the bulletin, please send your name, company/organization name, and address with zip code to Environmental Assistance Division US EPA (TS-799) 401 M Street, S W Washington, D C 20460 Editor Jane Gurin January 1991 31 ------- Do You Want to be Taken Off Our Maihng L.sf TSCA Hotline We like to think that the Chemicals-in-Progress Bulletin is worthwhile to everyone who receives it Now that our mailing list has grown to more than 10,000 names, though, we realize there may be a number of people who would prefer not to receive it any longer If you're one of those people, please fill out the form below or tape onto it the mailing label from your issue of Chemicals in-Progress Bulletin Then, mail it to the following address Environmental Assistance Division US EPA (TS-799) 401 M Street, S W Washington, D C 20460 The TSCA Assistance Information Service (TSCA Hotline), (202) 554-1404, operates Monday through Friday, from 8 30 am to 5 p m Eastern time FAX requests for documents are received every day, at all times, on (202) 554-5603 To request assistance by mail, write to the TSCA Assistance Information Service, Office of Toxic Substances (TS-799), EPA, 401 M Street S W, Washington, D C 20460 Thanks for taking my name off the mailing list for Chemicals-in-Progress Bulletin Name Company/Organization Name Street Address City, State, Zip Code Environmental Assistance Division (TS-799) Official Business Office of Pesticides & Toxic Substances Penalty for Private Use USEPA WOO Washington D C 20460 First Class Mall Postage and Fees Paid EPA Permit No G-35 THE CHEMICALS-IN-PROGRESS BULLETIN ------- |