UNITED STATES ENVIRONMENTAL PROTECTION AGENCY Region II, New York, New York 10278 DATE: SUBJECT: FROM: January 12, 1990 Risk Assessment Review P.E. nistrator William J. Merszyns Deputy Regional A William Farland, Ph.D. / / st\ Director (// Office of Health and Environmental Assessment Attached is a copy of the Risk Assessment Review, a bimonthly publication that is a cooperative effort between the Office of Research and Development and the Regional Risk Assessment Network. The Review serves as a focal point for information exchange among the EPA risk assessment community on both technical and policy issues related to' risk assessment. It is currently in its fourth year of publication and we are pleased at the positive feedback we*ve received on the Review's usefulness to staff across the Agency. Thanks to all of you who continue to contribute articles and are involved with production efforts. If you have an article to contribute or any suggestions for further issues, contact one of the Committee members listed on page 1 of the Review. Attachment ------- December 1989 Highlights • Risk Modeling and Geographic Information Systems(GlS) 1 • Interagency Task Force Sponsors Environmental Health Education Workshop ... 1 • ORD Regional Scientist Activities - Region 10 4 • New Superfund Risk Assessment Course .... 6 • Region 6 - Less-Than-Lifetime Exposures ... 6 • Ecological Risk Assessment in Region 10 .... 7 • Principles of Route-to-Route Extrapola- tion for Risk Assessment Conference 7 Risk Assessment Review Committee Bill Farland - ORD, FTS 382-7317 Sally Edwards - Region 1, FTS 835-3696 Maria Pavlova - Region 2, FTS 264-7364 Marian Olsen - Region 2, FTS 264-5682 Suzanne Wuerthele - Region 8, FTS 330-1714, Dana Davoli - Region 10, FTS 399-2135 I. Special Features Risk Modeling and Geographic Information Systems (GIS) by Dave Reieskl (FTS 382-2418) Jacques Kapuscinski (FTS 382-2418) Since the early 1980s, the EPA has been moving slowly towards what many have termed "risk-based decision making." This trend has recently been accelerated by an attempt to prioritize EPA programs at federal and some regional levels on a risk reduction basis. This process solidified significantly in 1987 with the publication of EPA's report "Unfinished Business: A Comparative Assessment of Environmental Problems," and continues with the follow-up work of The Relative Risk Reduction Strategies Committee organized by the EPA Science Advisory Board. In addition, a number of the regions (1,3, and 10) have been asked to critically assess their programs' funding levels based on "Cross Media or "In Media" risk. The message that is beginning to emerge from these activities is that risk-based priority setting is here to stay. The search for new methodologies and tools to support this effort will intensify. Paralleling this increased emphasis on risk as a decision-making tool has been the widespread dissemination of Geographic Information Systems, which have revolutionized the way we think about and manipulate spatial data. For many "risk managers," the use of GIS for risk assessment or analysis is intuitively obvious and offers many advantages including: the modeling of distributive health and ecological impacts, the potential for risk forecasting, and the possibility for improving risk communication with powerful graphics. Many people are now contemplating how GIS can play a role in risk projects, and a few people have already begun to think about the pitfalls and dangers of this approach (See: Timothy L. Amsden, "GIS and Risk Assessment: Dangerous and Wonderful Tools," Office of Ground Water Protection, E.P.A., Kansas City, Kansas.) (see GIS p.2) Interagency Task Force Sponsors Environmental Health Education Workshop by Maria Pavlova (FTS 264-7364) In the past year and a half, there has been a major shift in attitude and awareness about environmental issues. The public is becoming increasingly concerned about environmental issues and increasingly willing to make individual contributions to resolving them. At the same time, there is often a fundamental lack of understanding about risks to human health and the environment that affect choices about lifestyles and priorities. A substantially increased commitment to environmental health education is essential to creating an "environ- mental health literacy" that will enable informed involvement and decision making concerning the many environmental factors that potentially affect the health of U.S. citizens. There is a strong need for educators to promote critical thinking to help individuals grapple with scientific uncertainty regarding environmental risks, put risks into proper perspective, and develop skills for managing and reducing a range of health risks over a lifetime/This kind of education is especially important at the primary and secondary school levels, since many beliefs about environmental health issues are formed at an early age. Currently, very little classroom time is devoted to environmental health education in grades Kindergarten to 12. Most children are taught little or nothing about assessing health risks. Most children appear to have little or no basis for putting risks into perspective and for understanding debates about national environmental health issues. Current barriers to effective environmental health education include: 1) the low priority given to the topic by administrators and urban students: 2) lack of an adequate "niche" in, schools: 3) problems of coordination due to the decentralized nature of U.S. education; 4) lack of scientific literacy; 5) lack of teacher training; 6) lack of adequate "off-the-shelf" instructional materials; and 7) lack of funding. (see Task Force p.3) 1 ------- GIS (continued from p.1) Given this background, the Information and Technology Integration Branch within OIRM in headquarters is collecting information from all regions to find out "who is doing what" with GIS and risk. Based on an initial phone survey, we found that many regions are either in the early stages of developing risk models for GIS or are discussing how to integrate these two techniques. OIRM wants to facilitate the coordination of information among regions on the various types of GIS systems and risk assessment/analysis approaches that are being contem- plated across the country. By gathering and disseminating information on the status of GIS-based risk modeling, we hope to help regions identify problems early and share information on successes they are experiencing. Though not an exhaustive list, here are some examples and general descriptions of the status of GIS/Risk projects: Region 1 views GIS as a mapping tool and not a definitive decision model. The "Comparative Risk Project" in New Hampshire is developing a decision tool to integrate with GIS to help set priorities for Superfund, LUST, and RCRA sites. Region 3 is conducting a pilot project with forty facilities utilizing Toxic Release Inventory data with GIS in order to identify levels of ground water contamination and prioritize sites for cleanup. Region 5 is currently discussing how to integrate GIS with Risk. A pilot project on Lake Erie is utilizing GIS with TRI data to plot information on Superfund Sites utilizing all of the medias, fish tissue information, and human health effects. Region 6 GIS and Risk specialists met in mid- December to discuss how to integrate risk assessment with GIS. Region 7 is conducting a pilot project utilizing GIS with Agricultural Non-point Source Pollution (AGNPS) Model to identify critical non-point pollution areas to place priorities on planning resources for Best Management Practices for non- point source pollution control. Based on our initial survey, we will be putting together a fuller summary of GIS/risk projects in the regions for an upcoming edition of Risk Assessment Review. As part of this project, we have also tried to identify issues and areas which need to be addressed, clarified, and debated by those involved in GIS-based risk work. In each case we have attempted to describe opportunities for GIS as well as potential problems and pitfalls. We invite your additions and comments. 1. Modeling approaches Many of the more common analytical risk models will be difficult to implement in existing GIS environments. There are two possible approaches to this problem: c Use GIS to add cartographic output capabilities to existing computer models (for instance, mapping the calculated risk values around a hazardous waste site), or. • Develop models appropriate to the GIS technology. This will necessarily involve a shift from "deterministic process" to "empirical" models using threshold, proximity, and/or indicator approaches. Though quantitatively less precise, such models offer considerable cost savings while often providing enough precision for broad policy decisions. Much work needs to be done to support model development, evaluation, and dissemination to potential end users. Two ways of dealing with the modeling problem come to mind. One is to set up an informal consulting group of people inside and outside of EPA who have done modeling with GIS and are willing to share their insights with others. A second, longer term approach would be to establish a model library or clearinghouse containing useful and proven models either in hardcopy:or macro form. In connection with the modeling issue, we are also interested in evaluating the appropriateness of certain GIS systems for model development and implementa- tion. For instance, are people having trouble using ARC/INFO for risk modeling? 2. Dealing with increases in uncertainty Those contemplating the use of GIS for risk work need to realize that the use of GIS will introduce new sources of uncertainty into an already "messy" process. Three types of uncertainty need to be more fully addressed: parameter, locational, and linguistic. Parameter uncertainty. Much of the work in risk assessment is fraught with uncertainty about critical input parameters such as ambient pollution levels, unit risk factors, demographic patterns, etc. In addressing parameter uncertainty, GIS offers two diametrically opposed options: • Hide the uncertainty behind pretty maps (common approach), • Carry the uncertainty on secondary "shadow maps" which allow the statistical error to be calculated through each step of the model and displayed with the final results map (preferred option). Locational uncertainty. Though not the primary cause of locational errors, the use of GIS is likely to compound this problem by introducing errors arising from digitizing or the rasterization of vector data. In the long term; this problem will be aided by the adaption of locational data standards and the use of new geopositioning tools such as the Global Positioning System. In the near future, however, low locational data quality will affect all analyses. Linguistic uncertainty. Hardly addressed up to now are issues of linguistic uncertainty (uncertainty of descrip- tion) common to any approach, GIS-based or not. Much of the debate about risk is waged with linguistic descriptors such as: acceptable, tolerable, high, and low. Unfortunately, there is considerable disagreement among scientists, policy makers, and lay people about the quantitative limits and thresholds associated with these terms. Few risk analyses take into account differential risk perceptions in the population and allow 2 ------- for a consideration of the inherent imprecision in describing risk. In mapping risk, the boundaries between risk categories can never be sharp lines. New techniques need to be developed which allow a cartographic representation of our descriptive uncertainty through the mapping of "fuzzy" boundaries. The ability to map differential risk perceptions would also be of tremendous value (for instance, how do an epidemiologist, policy maker, and lay person view a given risk situation). Basic to all the uncertainty problems outlined above is the need to incorporate robust mathematical measures of uncertainty and imprecision into every step of the analytical process. The EPA needs to carefully assess the marginal economic utility of increased investments in data quality, versus the development and increased use of uncertainty measures. These should be based on techniques such as decision analysis or fuzzy set theory which force us to define our certainty/uncertainty and incorporate these measures into our analyses. 3. Questions of social equity GIS is not likely to solve the problems of setting limits to acceptable or tolerable risks. It will, in fact, add an additional area of concern to an already murky science by "regionalizing" the risk assessment process. Because of the ability of GIS to display spatial distribution patterns, difficult political and ethical questions will arise concerning the equitable distribution of risk across populations in space. The redistribution of risk will be a political act, requiring tough political decisions that the EPA should, and must, face. If the political will exists, GIS may aid in addressing the equity issue. GIS techniques could be used to support risk-based land use planning or to target pollution prevention strategies at the historically "risk disadvantaged." In the long term we will have a choice: to sidestep or confront the issue of risk equity. We realize that we have raised more questions than we have answered. We hope that you will join us in addressing some of these issues. If you can provide any information on the types of risk modeling you are doing, and/or if you have thoughts to share on integrating Risk Assessment with GIS with respect to potential benefits and drawbacks, please contact Dave Rejeski or Jacques Kapuscinski at FTS 382-2418 or E Mail Box EPA30435. Task Force (continued from p.1) The Interagency Task Force on Environmental Cancer and Heart and Lung Disease will sponsor a workshop in the spring of 1990 on environmental health education. The task force was established by Congress in 1977 to promote coordination and cooperation in efforts to reduce or prevent environmentally related diseases. The task force currently includes representatives from 16 federal agencies and is chaired by the EPA Administra- tor. Its Subcommittee on Public Education and Risk Communication works to enhance the ability of the public to participate in decisions affecting its health and welfare, and to make personal decisions concerning risks. The goals of the spring 1990 workshop on environmental health education will include: • Bringing together participants from the fields of education, environment and health to identify common goals for a comprehensive program. Most environmental education in the schools has focused on ecology issues rather than the relationship between environmental degradation and health; this conference will aim to forge closer links between environmental and health educators. • Developing a network of practitioners and decision makers in the field of environmental health education and promoting cooperation among federal agencies that include education as part of their mission. • Reviewing existing environmental health .education programs and curricula, to identify successful approaches to infusing environmental health education into existing courses, to better understand research needs in this area, and to avoid duplication of effort. • Establishing pilot programs to evaluate the effectiveness of environmental health education programs. • Identifying barriers to establishing environmental health education in the schools and strategies for overcoming these barriers. • Determining ways to provide teachers with guidance and training on what to teach and how to teach it. The task force held a one-day mini-workshop in Washington, D.C. on November 29, 1989, to plan the spring 1990 workshop. Forty education, communica- tions, and environmental and health science specialists representing federal governmental agencies, univer- sities, educational and health associations, and. private organizations attended the workshop and discussed needs, options, and recommendations for increasing the national commitment to environmental health education. Lewis Crampton, Associate Administrator for Communications and Public Affairs at EPA, presented the Agency's perspective on the importance of environmental health education. He informed the group about a proposed Office of Environmental Education within EPA's Office of External Affairs- to promote environmental health education in the schools. The spring 1990 workshop will be the third risk communication meeting sponsored by the Interagency Task Force. The first one, held in January 1987 discussed the role of government in risk communication and public education. The second, held in June 1988, looked at the issue of evaluating effective risk communication. The task force is also planning a national conference on risk communication for the spring of 1991. For more information on this conference or the upcoming environmental health education workshop, contact Maria Pavlova, Chairperson, Interagency Task Force Subcommittee on Public Education and Risk Communication at FTS 264-7364. 3 ------- II. Headquarters ORD Regional Scientist Activities - Region 10 by Spencer A. Peterson (FTS 399-214$) This is the fourth in a series of articles describing the Regional Scientist Program out of the Regional Operations Staff, ORD. My responsibilities in Region 10 have been diverse like those of other regional scientists. They have ranged from assessing research needs, to assisting ORD to coordinate research activities on bioremediation of the Alaskan oil spill, to speaking on behalf of the region at a National Water Quality Conference, to assisting the Regional Administrator develop a travel itinerary to explore pollution prevention in Japan, to equipping the regional laboratory. Rather than try to highlight all activities, I will focus on one fairly complex effort in which I have played a key role. Shortly after arriving in Region 10, I was introduced to a concept completely foreign to me. It was laboratory robotization. The region had been approached by an outside research group with a proposal to "build" a laboratory robot capability. It was attractive for a variety of reasons. The proposal promised: 1) To increase lab through-put of sediment samples by robotizing the sample preparation phases, 2) To improve precision and accuracy (Quality Control) of analyses by making all steps of the sample preparation uniform, 3) To use lab technician time more efficiently, which, in combination with number one above, reduces overall analytical costs, and 4) To minimize potential technician exposure to hazardous chemicals in the soil samples. The down side of the proposal was that it required substantially more funds than the region could devote to it. In addition, it was clear that the technology was not off the shelf at this time and would require additional research and development time. I was asked to explore the proposal further. Roughly translated, this meant find out everything you can about the potential for robots to conduct soil sample preparation steps through acid digestion, and, if it appears feasible, find the resources to complete the project. The feasibility exploration took me to both industrial and laboratory robot manufacturers. This field was finally narrowed to one commercial manufacturer of laboratory robotic equipment. Their off-the-shelf capabilities came closer to our perceived needs than any other manufacturer. However, it also was clear that custom design and fabrication would be necessary since we were interested in up-scaling the digestion process to microwave capability, which would greatly reduce sample preparation time over the normal hot-plate procedure. A major problem was the lack of computer software to interface the robot with the microwave oven. The oven was still under development by another manufacturer working with the robot manufacturer. We were truly dealing with the state of the art. The National Bureau of Standards and Technology (NBST) was testing prototype microwave equipment and developing a standard software program. The region, through EMSL-Las Vegas, bought into the NBST project. Funding to acquire the robotics equipment and software programs was eventually realized from four different sources. The region received S125K from sources outside the region for the project. These sources included the National Environmental Services Office, the Office of Program Management and Technology (OSWER), the Quality Assurance and Methods Development Division (EMSL-Las Vegas), and EMSL- Cincinnati. As part of the agreement in procuring the robotics equipment, Region 10 will participate with EMSL-Las Vegas in an inter-laboratory quality comparison test. The region and EMSL-Las Vegas will have duplicate equipment. We have now laid out a schedule for completion of the project. If all goes well, this should turn out to be a win- win situation for all participants. The region gets robotics equipment to accomplish-the four initial "promises," EMSL-Las Vegas gets the highly controlled inter- laboratory tests they wanted, the National Environmental Services Office accomplishes one of its goals to assist the regions, and EMSL-Cincinnati has bought into the initial phase of procedures designed to standardize software programing (NBST) for laboratory robotics equipment in EPA. This was an extremely convoluted project that has taken nearly one year of intermittent effort to this point. It is not yet complete, but I have full confidence it will be finished according to current schedule. It has the potential to revolutionize soil sample preparation and analysis, thereby making a contribution far beyond the region. The Federal-State Toxicology and Regulatory Alliance Committee by Bob CantUII (FTS 382-5546) Ed Ohanian (FTS 382-7571) The Federal-State Toxicology and Regulatory Alliance Committee, or FSTRAC, first met in April 1985 to begin a cooperative effort between federal and state regulators and risk assessment programs to address drinking water issues. FSTRAC is made up of representatives from state health and environmental agencies, the U.S. Environmental Protection Agency's (EPA) Office of Drinking Water, and regional EPA programs. FSTRAC brings together professionals with many different areas of expertise to develop well-rounded, integrated approaches to risk assessment and for drinking water contaminants standard setting issues. Representatives from academia, industry, and consulting groups are also welcome to participate - collaboration and exchange of ideas between all these groups will improve the success of regulatory programs. Although there is no specific legal mandate for FSTRAC, interaction and cooperation between state and federal agencies can lead to important exchanges of information and experience on regulatory matters. EPA sponsors FSTRAC to: 4 ------- • Foster cooperation among states, and between the states and EPA. State and federal officials can discuss and understand risk assessment issues. • Provide a setting for informal and formal discussion of common problems. • Improve consistency between federal and state approaches to setting standards or guidelines for drinking water contaminants. • Obtain feedback on proposed federal guidance and standards. • Conduct research on factors influencing state risk assessment and drinking water regulatory programs. FSTRAC has two ongoing subcommittees, the Chemical Communication Subcommittee and the Risk Assessment Subcommittee, that break down further into workgroups as the need arises. Members meet twice a year; subcommittees often hold additional teleconferences to discuss projects. Technical presentations on proposed regulations, new research, and ongoing standard-setting activities at EPA are presented at the biannual meetings. FSTRAC members also meet with their subcommittees to plan activities and projects. At every meeting there is an opportunity for states and regions to discuss issues of common interest, possible solutions, or to discuss specific standard-setting procedures by the states or EPA. The meetings serve FSTRAC's goal of bringing together officials from across the country to discuss issues of mutual concern, establishing a national communication network. This network provides states, regions and federal government access to information that can improve regulatory action and avoid duplication of effort. Some of the topics that have been discussed at past FSTRAC meetings are: • Carcinogen Risk Assessment Guidelines Update, • National Pesticide Survey - Pesticide Monitoring Inventory, • Northeast Regional Environmental Public Health Center - Current Research, • The Connecticut Radon Survey, • Potential Effects of Contaminants on the Immune System, • Non-lngestion Exposures: Volatile and Dermal Absorption. • What is an Adverse Effect? • How to Conduct Risk Assessments with Limited Toxicological Data. FSTRAC Products The mix of expertise and experience among the federal, regional, and state FSTRAC members has led to the production of many useful outputs that are used for setting standards: • Guidance Document for the Risk Assessment of Chemical Mixtures in Drinking Water. Provides guidance to regions and states on how to establish health goals for drinking water that has been contaminated by a mixture of chemicals. • Summary of State and Federal Drinking Water Guidelines and Standards. A report listing specific standards and regulations for 312 drinking water contaminants compiled from a FSTRAC-sponsored survey. Forty-four states participated in the survey, which was updated in 1989. • Guidance Document on the Assessment of Non- lngestion Exposure to Drinking Water Contaminants. This report, still in progress, will provide guidance for assessing the risks from dermal and inhalation exposure to contaminants in drinking water. • Risk Communication Bibliography. Descriptions of pamphlets and booklets that address drinking water risk communication issues, and risk communications materials, such as fact sheets, that address the risks posed by specific chemicals. All of the documents listed are available from FSTRAC's library at EPA Headquarters. • Surveys. FSTRAC workgroups have compiled information from states regarding risk assessment methodologies, and occurrence data for drinking water contaminants.- These are labor-intensive projects that provide useful information concerning different states! programs. FSTRAC also provides peer review assistance to EPA and the states, for example, by reviewing Office of Drinking Water Health Advisories. Future FSTRAC Meetings The next FSTRAC meeting will be held in Washington, D.C., in April 1990. This meeting will include a Risk Assessment Methodologies workshop to instruct participants in EPA and the states in risk assessment methods and policies. A panel of FSTRAC members will discuss practical solutions to hypothetical toxicological problems encountered by states and EPA regions. For information on joining FSTRAC, contact: Dr. Edward Ohanian, Chief, Health Effects Branch (WH-550D), Office of Drinking Water, U.S. EPA, 401 M Street, S.W., Washington, D.C. 20460, FTS 382-7571. The Co-chairs of the Chemical Communication Subcommittee are: Carolyn Jean Dupuy, Connecticut Department of Health Services, 150 Washington Street, Hartford, CT. 06106, (203) 566-8167, and Leslie McGeorge, New Jersey Department of Environmental Protection, CN-409, Trenton, N.J. 08625 (609) 292-4938. The Co-chairs of the Risk Assessment Subcommittee are: Lubow Jawa, New Jersey Department of Environmental Protection, 401 East State Street, Trenton, N.J. 08619 (609) 633-1316, and Bela Matyas, Rhode Island Department of Health, 206 Cannon Building, 3 Capitol Hill, Providence, Rl 02909 (404) 277- 3424. Risk Assessment Guidelines Training by Bette Cantor (FTS 475-6743) Risk assessment guidelines facilitators are presenting guidelines training courses to staff in the Office of Pesticide Programs this fall and winter. About 128 people in the Health Effects Division will take the 5 ------- training. This represents the largest group from a single office to receive the guidelines training so far. Six courses are being offered, which include the Managers' Seminar and a course for each of the five risk assessment guidelines issued in 1986: developmental toxicity, cancer, mutagenicity, chemical mixtures, and exposure. We are scheduling a total of 25 courses so that each staff member may attend the courses that are most relevant to his or her expertise. New Superfund Risk Assessment Course by Pat Mundy (FTS 475-9495) The new Risk Assessment Guidance for Superfund: Environmental Evaluation Manual and Human Health Evaluation Manual has been incorporated into a course offered by the Environmental Response Team in the Hazardous Materials Incident Response Training Program. The course has been given to Regions 4 and 5 and the U.S. Army Corps of Engineers, and the team will travel to the remaining regions this fiscal year. The course is titled Risk Assessment Guidance for Superfund (165.6) and runs four and one-half days. Toxics Integration Branch (TIB) members have been attending and encourage Regional Toxics Integration Coordinators to attend to lend regional perspective and relate issues of current interest. For course scheduling and registration information, contact Training Registrar, EPA Training Registration, NUS Corporation, 3280 River Road, Cincinnati, Ohio 45204, (513) 251-7776. The Toxics Integration Branch can be reached at FTS 475- 9486. III. Around the Regions Region 6 - Less-Than-Lifetime Exposures Fred Hauchman (OAQPS) and Jon Rauscher (Region 6) are conducting a survey to identify the airborne chemicals of greatest concern in the Superfund program. Risk analyses of less-than-lifetime exposures to airborne contaminants have been of increasing importance to the regions. This subject will be of particular concern as projects move into the remedial action phase. Remedial activities such as soil handling can result in significant emissions of volatiles and dusts. The final ranking will identify chemicals to be used by the Office of Air Quality Planning and Standards in conducting a literature review of less-than-lifetime exposures. This literature will be used to evaluate the feasibility of developing less-than-lifetime risk estimates. Contact: Jon Rauscher (FTS 255-6715) Region 8 - Risk Training Marilyn Null from the Region 8 Office of External Affairs has developed a risk communication component for inclusion in the Workshop on Risk and Decision Making. The risk communication component provides presenta- tions on risk communication tools and techniques and involves participants in role playing at a mock meeting between government agencies and the public. This revised two-and-one-half day version of the workshop was previewed for the first time to about 30 staff at the Wyoming Department of Environmental Quality (DEQ) in September and was very well received. In fact, the DEQ Administrator, Dennis Hemmer, personally requested that the workshop be offered again so that he and his senior managers could attend. This second session took place in early December and was again very well received. On both occasions, DEQ personnel indicated that the risk communication component made the workshop much more valuable. The Risk Assessment Guidelines: Managers' Seminar was presented three times in Region 8 during December. Dorothy Patton (ORD/RAF) facilitated the course in North Dakota on December-13 and twice at the~ Region 8 Institute on December 14. Region 8 plans to offer the Workshop on Risk and Decision Making four more times during FY90. These sessions are planned for federal, state, and local government personnel in Colorado, North Dakota, Montana, and Utah. Region 8 also plans to sponsor the Risk Communication Workshop and the Risk Assessment Guidance for Superfund training several times in FY90. Contact: Patrick Cummins (FTS 330-1610) OHEA Sabbatical I am currently on a 120-day detail to the Office of Health and Environmental Assessment's (OHEA) Human Health Assessment Group. My project was to meet ORD's scientists there, learn how they generate cancer risk numbers, and translate some of the more confusing aspects of that process into "regionalese." I'll let you decide at the risk assessor's meeting in Chicago if my "document" is helpful. I also promise to give you some useful hints on how to find the scientists and get information from them. This mini-sabbatical has been an outstanding experience that I highly recommend if you get the opportunity. There are some very good people here who specialize in our most troublesome pollutants, are generous with their time, and are willing to give us some scientific insight both for our risk assessments and for risk communication. In return, we can show them that their work has a practical application. Contact: Suzanne Wuerthele (FTS 330-1714). Region 9 On December 15, 1989, Region 9's Toxicology Group held an all day workshop for their ARCS contractors involved in risk assessment. The focus of the workshop was the new Risk Assessment Guidance for Superfund; discussions were held on human health and ecological guidelines. Gerald Hiatt, Ph.D., and David Lewis, Ph.D., gave presentations covering the new human health risk assessment guidelines, and Sharon Seidel, Ph.D., addressed the ecological assessment guidance. The goals of the workshop were to promote consistency 6 ------- among the ARCS contractors in their approach to risk assessment for Superfund and to provide guidance concerning the Toxicology Group's interpretation of these new guidelines from Headquarters. Contact: Arnold Den (FTS 484-1776) Ecological Risk Assessment in Region 10 First noticed by duck hunters in 1981, waterfowl dieoffs have been documented yearly during annual migrations through a 2500-acre wetland known as Eagle River Flats, which occupies the northwest corner of Fort Richardson Army Base, AK. The Flats consist of the main channel and side channel of Eagle River as it forms tidelands which intercept the Knick Arm of Cook Inlet, abo.ut 15 miles north of Anchorage. From the 1940s through the present time, the central part of the Flats area has been used as an "impact area" for mortar and artillery fire. Consequently it now contains high concentrations of unexploded ordnance materials and 6-foot impact craters which make it unsafe for random access and sampling. From 1982 through 1988, an estimated 2000 dead birds have been noted at the site, with several hundreds more observed in 1989. However, because of off-limits access constraints, area size and sampling/visibility problems, these figures represent only about 8 per cent of the entire Flats area. Almost all carcasses" anij' feather piles are those of ducks, with pintails (Arias a'cutd) the most common species affected. Several other dead avian taxa have been found, including shorebirds and an occasional raptor. Affected birds appear to die quickly, and: predation on dying waterfowl by bald eagles is a major occurrence. Sampling efforts and analytical/ pathologic studies thus far have been uniformly inconclusive. However, US Fish and Wildlife Service scientists have ruled out disease and concussion from artillery fire as causative agents, and current attention is increasingly focused upon munitions chemicals which comprise the on-site ordnance. In 1987, a task force was formed to address the problem, and consisted of The US Fish and Wildlife Service, US Army, EPA Alaska Operations Office, Alaska State Dept of Environmental Conservation, and Alaska State Fish and Game. Under contract to the US Army Toxic and Hazardous Materials Agency (USATHAMA), a private Colorado firm has developed an expanded site investigation scope of work to ascertain the cause of the bird deaths. This will include residue and tissue sampling, the use of sentinel birds, and other types of studies. This important wetland is a significant issue in terms of ecological risk assessment. Contact: Dana Davoli (FTS 399-2135) IV. Announcements Principles of Route-to-Route Extrapolation for Risk Assessment Conference EPA and the ILSI Risk Science Institute in Washington, D.C., will host a conference on the Principles of Route- to-Route Extrapolation for Risk Assessment from March 19-21, 1990. The conference will be held at the Mariner's Inn, in Hilton Head, South Carolina. The conference will feature invited speakers and poster presentations on: • Structure and function of barriers to uptake of toxicants, • Physiological parameters associated with uptake of toxicants, • Critical factors for modeling systemic dose of toxicants, • Implications for route extrapolations, and • Implications for risk assessment and future research needs. Toxicologic data often exist for routes of exposure'other than the route by which humans are environmentally exposed. This conference is concerned with the scientific issues related to route-to-route extrapolation as it is applied in risk assessment. The registration fee for the two-and-one-half day conference is $150.00. For further information about attendance contact: Janice Braswell, Conference Coordinator, NSI-ES, P.O. Box 12313, Research Triangle Park, North Carolina 27709. Janice can be reached at (919) 549-0611. Society for Risk Analysis Course Announcement The Society for Risk Analysis will hold their fifth annual course, "New Directions in Cancer Risk Assessment" on May 21-23, 1990, at the Hyatt Regency Hotel, Bethesda, Maryland. The intent of the course it to provide an introductory overview of methodologies, assumptions, and new research in cancer risk assessment. Lecturers will show how to perform and interpret risk assessments and how to use them in risk management. Special emphasis will be given to new developments in pharmacokinetics, biomonitoring and reproductive, immunological and neurological risks. Lecturers will be Dr. Roy Albert, Professor and Chairman, Department of Environmental Health and Kettering Laboratory, University of Cincinnati; Dr. Elizabeth Anderson. President, Clement Associates, Inc.; Dr: Mildred Christian, President and Director, Argus Research Laboratories. Inc.; Dr. Vincent Covello, School of Public Health, Columbia University; Dr. Bernard Goldstein, Professor and Chairman, Environmental and Community Medicine, Robert Wood Johnson Medical School; Dr. Loren Koller, College of Veterinary Medicine, Oregon State University; Dr. Lester Lave, Graduate School of Industrial Administration, Carnegie-Mellon University; Dr. Richard Reitz, Associate Scientist in Toxicology, CUT; Dr. Ellen Silbergeld, Environmental Defense Fund; Dr. Curtis Travis, Director, Office of Risk Analysis, Oak Ridge National Laboratory; Dr. James Trosko, Professor of Pediatrics and Human Development, University of Michigan; Dr. Chris Whipple, Technical Manager, Risk and Health Science Department, Electric Power Research Institute. For further information, please call 7 ------- Dr. Curtis C. Travis, (615) 576-2107 or FTS 626-2107, or Mary Oran, (615) 574-8438 or FTS 624- 8438. The following is the schedule for the Risk Communication Workshops through March: Stormwater and Group Meeting Water Quality Model Users The Stormwater and Water Quality Model Users Group Meeting will be held on April 26-27, 1990, at the Sheraton Eatontown Hotel and Conference Center located at Hwy 35 and Industrial Way East, Eatontown, New Jersey. The telephone number is (201) 542-6500. Registration for the conference is $75.00. Further information on the conference can be obtained from the conference coordinator: Vajira Gunawardana, P.E., Najarian and Associates, Inc., One Industrial Way West, Eatontown, New Jersey 07724. The telephone number is (201) 389-0220. Abstracts of presentations on all aspects of Stormwater and Water Quality Modeling are invited to be submitted to the conference coordinator by February 1, 1990. Authors will be notified of acceptance by March 1, 1990. An agenda for the meeting will be available in March 1990 with further details and travel information. 2nd International Conference on Watermatex '91 r The International Association on Water Poll&tiain-^ Research and Control will host the 2nd International Conference on Watermatex '91 from June 3-6, 1991, at the New England Center, University of New Hampshire, l>! Durham, New Hampshire. The Conference title is "Systems Analysis in Water Quality Management/ and Clinic on Computer Simulation of Environmental Processes." The goal of the meeting is to bring together research and applications in system analysis to examine these issues and bridge theory and practice. The association is soliciting technical papers in the area of systems analysis in water quality management with special consideration being given to papers with special emphasis on contemporary issues and computer applications. Papers should be submitted by December 1, 1990. For further information on the meeting, contact: WATERMATEX '91, New England Center Program Office, 15 Stafford Avenue, University of New Hampshire, Durham, New Hampshire 03824 at (603) 862-1900. Risk and Decision-Making Courses Scheduled The following is the schedule for the Risk and Decision- Making Courses through March: Headquarters - Region 2 Headquarters - Region 3 January 23-24 February 14-15 March 6-7 March 15 Contact: Marian Olsen (FTS 264-5682) Jim Cole - Headquarters (FTS 382-2747) Contacts: Jerome Puskin Linda Tuxen Dorothy Patton Dick Hill Don Barnes Dean Hill Sally Edwards Marian Olsen Jeffrey Burke Elmer Akin vMtl{ Clark '\ , Jon Rao^eh^r^ Bob Fenemore •• Suzanne \Mu^thele Arnold Den' Dana Davoli .?A'S OAR-RAD ORD-OHEA ORD-RAF OPTS SAB NEIC Region 1 Region 2 Region 3 Region 4 ion 5 ion 6 Region 7 Region 8 Region 9 FTS 475-9640 FTS 382-5949 FTS 475-6743 FTS 382-2897 FTS 382-4126 FTS 776-8138 FTS 835-3696 FTS 264-5682 FTS 597-1177 FTS 257-2234 FTS 886-3388 FTS 255-6715 FTS 757-2970 FTS 330-1714 FTS 454-0906 FTS 399-2135 Need Help? If your office needs help in finding information or assistance on a specific risk assessment problem, you can announce that need on the Risk Assessment/Risk Management Bulletin Board now available on E-Mail. Your colleagues from other offices who have information or advice will be able to contact you with assistance. For assistance in posting announcements or reading entries on the Bulletin Board, contact Electronic Mail User's Support at FTS 382-5639. Your colleagues from other offices who have information or advice will be able to contact you with assistance. Region 6 Region 7 Region 2 Region 5 Region 3 January 23 and 24 February 21-11 March 7-9 March 13-14 March 14 If you would like to receive additional copies of this and subsequent Reviews or to be added to the mailing list contact: CERI Distribution 26 West Martin Luther King Drive Cincinnati, Ohio 45268 8 ------- |