&EPA
www.epa.gov/airscience
science   in  ACTION
                                                                CLEAN AIR  RESEARCH
                                                                PROGRAM
      AIR POLLUTION RESEARCH IMPROVES UNDERSTANDING OF
      MULTIPOLLUTANT IMPACTS ON HUMAN HEALTH
      Issue:
      People are exposed to mixtures of
      air pollutants throughout life.
      Clear advances have been made
      in understanding and minimizing
      the risks associated with some air
      pollutants with known singular
      toxicity risk, but the impacts of
      mixtures of low levels of air
      pollutants are still uncertain.

      Historically, outdoor air research
      has largely focused on individual
      air pollutants like particulate
      matter (PM), ozone, or priority
      hazardous air pollutants (HAPs).
      This research has been critical for
      the development and
      implementation of clean air
      standards by the U.S.
      Environmental Protection
      Agency. As a result, air quality in
      the United States has improved.

      To further advance air quality
      management, EPA is adding a
      multipollutant component. This
             "one atmosphere" approach takes
             into account that humans and
             ecosystems are exposed to many
             air pollutants at the same time,
             and that there exist many
             atmospheric processes and
             conditions that underlie this mix
             of pollutants.

             Currently, each pollutant is
             assessed separately and controlled
             by independent measures. A
             multipollutant approach offers an
             opportunity to more effectively
             target air pollutants at their
             sources and reduce more than a
             single pollutant with control
             measures. The desired outcome is
             to have a broader impact on
             outdoor air pollutant levels and
             reduce the cost of pollution
             control.

             Multipollutant approaches to
             environmental decision making
             require new science to understand
             and appreciate the complexities of
             co-pollutant interactions
(chemical and biological). More
advanced scientific methods,
models and tools are needed.

In response, the Clean Air
Research Program in EPA's
Office of Research and
Development is shifting toward a
multipollutant approach to air
research. This research emphasis
is based on recommendations by
science advisory groups,
including the
National Research Council,
Science Advisory Board, and
Board of Scientific Counselors,
which have encouraged EPA to
transition from individual
pollutant control and regulation to
an air quality management theme
that includes multipollutants.

Scientific Objective:
The Clean Air Research Program
has developed a three-pronged
strategy to address multipollutant
issues that builds on earlier
scientific contributions in this
area.  The strategy integrates the
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       U.S. Environmental Protection Agency
       Office of Research and Development

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  &EPA
www.epa.gov/airscience
science   in   ACTION
      CLEAN AIR RESEARCH  PROGRAM
      continued from front
      many scientific disciplines that
      advance knowledge about air
      pollution. These disciplines
      include the study of sources and
      atmospheric processes, the study
      of how people are exposed, and
      subsequent health implications.

      The strategy includes:

      • Conducting laboratory studies
        to evaluate controlled source
        emissions and health effects.
        Conducting laboratory studies
        of artificial mixtures that test
        hypothetical interactions that
        may be driving more
        generalized atmospheric
        exposure mixtures.
      • Conducting real-world studies
        in cities where emission,
        exposure, and health data can
        be collected or integrated on
        multipollutant exposures that
        may impact human health.

      Areas of scientific focus include:

      • Understanding the relationships
        between sources of air
        pollutants and atmospheric
        transformation (secondary) air
        pollutant products.
             • Understanding the health risks
               posed by mixtures of air
               pollutants.
             • Advancing atmospheric and
               exposure modeling of
               multipollutants.
             • Developing methods and
               controls for sources or air
               pollutants that impact health
               relevant emissions or products.
             • Determining a hierarchy of
               sources and related emission
               components regarding relative
               health risks.

             As part of this effort, there is an
             initial emphasis directed to near-
             road exposures since mobile
             sources emit a complex mix of
             gases, vapors, and particles.

             Application and Impact
             The Clean Air Research Program
             has already made significant
             contributions to our
             understanding of multipollutants.
             Work has revealed how
             multipollutants are generated as
             primary emissions as well as
             secondary transformation
             byproducts. Scientists have also
             expanded the capabilities to
             measure multipollutants.
There also have been advances in
our understanding of how people
are exposed and impacted by
mixtures of pollutants.

The research program has led the
way in multipollutant
assessments. The atmospheric
model called the Community
Model for Air Quality (CMAQ)
has recently been expanded
beyond just predicting ozone
pollution to include PM and a
host of air toxics or hazardous air
pollutants as well. This model is
used by states and local air
quality managers to develop
implementation plans to meet
EPA's air quality standards and is
used by other researchers
conducting epidemiology studies.
REFERENCES
Office of Air Quality Planning and Standards: The
Multi-pollutant Report: Technical Concepts &
Examples
http://www.epa.gov/air/airtrends/studies.html
CONTACT
Dan Costa, National Program Director, Clean Air
Research Program, EPA's Office of Research and
Development, 919-541-2532, costa.dan@epa.gov.

JANUARY 2009
      U.S. Environmental Protection Agency
      Office of Research and Development

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