United States
Environmental Protection
Agency
Final Contaminant Candidate List 3
Chemicals: Identifying the Universe

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Office of Water (4607M)
EPA815-R-09-006
August 2009
www.epa.gov/safewater

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EPA-OGWDW                      Final CCL 3 Chemicals:                   EPA 815-R-09-006
                                Identifying the Universe                       August 2009
                             Table of Contents
1.0 INTRODUCTION	1
   1.1 Background	2
   1.2 Overview of the Data Source Assessment Factor Process	3
   1.3 Assessment Factors	5
     1.3.1  Relevance	6
     1.3.2  Completeness	6
     1.3.3  Redundancy	7
     1.3.4  Retrievability	8
   1.4 Supplemental Data Sources	9
   1.5 Additional Information	11
2.0 THE CCL 3 CHEMICAL UNIVERSE SELECTION PROCESS	12
   2.1 Chemicals in Occurrence and Health Effects Sources	12
   2.2 Chemicals in Health Effects Sources Only	12
   2.3 Chemicals in Occurrence Sources Only	13
   2.4 Refining the Initial Universe of Chemicals	15
3.0 REFERENCES	17
4.0 APPENDICES	18
   Appendix 1. CCL 3 All Data Sources - Assessment Table	Al-1
   Appendix 2. CCL 3 Universe of Data Sources	A2-1
   Appendix 3. CCL 3 Universe Supplemental Data Sources	A3-1
   Appendix 4. CCL 3 Data Source Descriptions	A4-1
   Appendix 5. CCL 3 Universe Chemicals	A5-1
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                               Table of Exhibits
Exhibit 1:  Flow Chart of the Data Source Assessment Process	3
Exhibit 2:  The Universe of Data Sources for the CCL 3 Process	4
Exhibit 3:  Examples of Retained and Redundant Sources	8
Exhibit 4:  Supplemental Sources that Meet the Assessment Factors of Relevance,
      Redundancy, and Completeness, but not Retrievability	10
Exhibit 5:  Overview of Data Evaluation for the CCL 3 Universe Selection Process	13
Exhibit 6:  Example of Universe Contaminants with Occurrence Data but no Health
      Effects Data	14
Exhibit 7:  Overview of Data Evaluation for the CCL 3 Universe Selection	16
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                    List of Acronyms and  Abbreviations



 ARS             Alternate Crops and Systems (ARS)

 ATSDR           Agency for Toxic Substances and Disease Registry

 CADW           Canadian Drinking Water Quality

 CAS RN          Chemical Abstract Service Registry Number

 CCL             Contaminant Candidate List

 CCL 3            EPA's third Contaminant Candidate List

 CCOHS           Canadian Center for Occupational Health and Safety

 CCRIS            Chemical Carcinogenesis Research Information System

 CDC             Centers for Disease Control and Prevention

 CDPR            California Department of Pesticide Regulation

 CEDI/ADI        Cumulative Estimated Daily Intake/Acceptable Daily Intake

 CERCLA         Comprehensive Environmental Response, Compensation, and Liability Act

 CERCLIS         Comprehensive Environmental Response, Compensation, and Liability Information
                  System

 CESARS          Chemical Evaluation Search and Retrieval System

 CICADs          Concise International Chemical Assessment Documents

 CPH             Classification of Pesticides by Hazard

 CUS/IUR         Chemical update system/inventory update rule

 DSSTox          Distributed Structure Searchable Toxicity Public Database Network

 EAFUS           Everything Added to Food in the United States

 EFDB            Environmental Fate Databases

 EMAP            Environmental Monitoring and Assessment Program

 EPA             United States Environmental Protection Agency

 FAO             Food and Agriculture Organization

 FDA             United States Food and Drug Administration

 FIFRA            Federal Insecticide, Fungicide, and Rodenticide Act

 GAP             Genetic Activity Profiles

 GRAS            Generally Regarded As Safe
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 HA              Health Advisories

 HEAST          Health Effects Assessment Summary Tables

 HEDS            Human Exposure Database System

 HPV             High Production Volume

 HSDB            Hazardous Substances Data Bank

 IARC            International Agency for Research on Cancer

 ICR              Information Collection Rule

 ILO              International Labor Organization

 IPCS             International Programme on Chemical Safety

 IRIS             Integrated Risk Information System

 IRPTC           International Register of Potentially Toxic Chemicals

 ITER            International Toxicity Estimates for Risk

 JECFA           Joint Expert Committee on Food Additives

 JMPR            Joint Meeting On Pesticide Residues

 LCSS            Laboratory Chemical Safety Summaries

 MPR             Maximum Permissible Risk

 MRL             Minimal risk levels (from ATSDR); or, Minimum reporting level, for analytical data

 N                Number of samples

 NAS             National Academies of Sciences

 NAWQA         National water quality assessment (USGS program)

 NCEA           National Center for Environment Assessment

 NCFAP          National Center for Food and Agricultural Policy

 NCOD           National contaminant occurrence database

 NDWAC         National Drinking Water Advisory Council

 NHANES         National Health and Nutrition Examination Survey (CDC)

 NHATS          National Human Adipose Tissue Survey

 NIOSH           National Institute for Occupational Safety and Health

 NIRS            National Inorganic and Radionuclide Survey

 NLM            National Library of Medicine
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 NOES

 NREC

 NRC

 NSF

 NSI

 NTP

 OECD

 OEHHA

 OPP

 OPPT

 PAFA

 PAN

 PBT

 PCBs

 PCCL

 PCS

 PDF

 PEAC

 PELs

 PPIS

 PPMP

 RAIS

 REDDs

 RTECS

 SCLP

 SDWIS

 SIDS

 SRC

 SRD
National Occupational Exposure Survey

National Reconnaissance of Emerging Contaminants

National Research Council

National Sanitary Foundation

National Sediment Inventory

National Toxicology Program

Organization for Economic Co-operation and Development

California Office of Environmental Health Hazard Assessment

Office of Pesticide Programs

Office of Pollution Prevention and Toxics

Priority-based Assessment of Food Additives

Pesticide Action Network

Persistent, Bioaccumulative, and Toxic Profiler

Polychlorinated biphenyls

Preliminary Contaminant Candidate List

Permit Compliance System

Pesticide Data Program

Palm Top Emergency Action for Chemicals

Permissible Exposure Limits

Pesticide Product Information System

Pesticide pilot monitoring program

Risk Assessment Information System

Reregistration Eligibility Decision Documents

Registry of Toxic Effects of Chemical Substances

Superfund Contract Laboratory Program

Safe Drinking Water Information System

Screening Information Data Sets

Syracuse Research Corporation

Source Ranking Database
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 SRS              Substances Registry System

 STORET         STOrage and RETrieval

 TEAM           Total Exposure Assessment Methodology Study

 TERA            Toxicology Excellence in Risk Assessment

 TOPKAT         The Open Practical Knowledge Acquisition Toolkit

 TRI              Toxics Release Inventory

 TSCA            Toxic Substances Control Act

 TSCATS         Toxic Substances Control Act Test Submissions

 UCM            Unregulated contaminant monitoring

 UCMR           Unregulated Contaminant Monitoring Regulation

 UCMR 1         First Unregulated Contaminant Monitoring Regulation

 UCMR 2         Second Unregulated Contaminant Monitoring Regulation

 UNEP            United Nations Environment Programme

 URCIS           Unregulated Contaminant Information System

 US               United States of America

 USDA            United States Department of Agriculture

 USGS            United States Geological Survey

 WERF            Water Environment Research Foundation

 WHO            World Health Organization
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1.0  Introduction
Every five years the United States Environmental Protection Agency (EPA) is required to
publish a list of contaminants (1) that are currently unregulated, (2) that are known or anticipated
to occur in public water systems, and (3) which may require regulations under the Safe Drinking
Water Act (SDWA). This list is known as the Contaminant Candidate List or CCL. SDWA
section 1412(b)(l) requires that in the development of the CCL, EPA consider specific data
sources and include the scientific community. EPA must evaluate substances identified in section
101(14) of the Comprehensive Environmental Response, Compensation, and Liability Act
(CERCLA) of 1980 and substances registered as pesticides under the Federal Insecticide,
Fungicide, and Rodenticide Act (FIFRA). SDWA also requires the Agency to consider the
National Contaminant Occurrence Database established under section 1445(g) of SDWA.
SDWA directs the Agency to consult with the scientific community, including the Science
Advisory Board (SAB). In addition, it directs the Agency to consider the health effects and
occurrence information for unregulated contaminants to identify those contaminants that present
the greatest public health concern related to exposure from drinking water.

EPA interprets the criterion that contaminants are known or anticipated to occur in public water
systems broadly. In  evaluating this criterion,  EPA considers not only public water system
monitoring data, but also data on concentrations in ambient surface and ground waters, releases
to the environment (e.g., Toxics Release Inventory), and production. While such data may not
establish conclusively that contaminants are known to occur in public water systems, EPA
believes these data are sufficient to anticipate that contaminants may occur in public water
systems and support their inclusion on the CCL. The Agency considered adverse health effects
that may pose a greater risk to life stages and other sensitive groups which represent a
meaningful portion of the population. Adverse health effects associated with infants,  children,
pregnant women, the elderly, and individuals with a history of serious illness were evaluated. In
selecting contaminants for the CCL 3, each of the above requirements was met.

SDWA section  1412(b)(l) also requires EPA to determine whether to regulate at least five
contaminants from the CCL every five years. SDWA specifies that EPA  shall regulate a
contaminant if the Administrator determines  that:
   •   The contaminant may have an adverse effect on the health of persons;
   •   The contaminant is known to occur, or there is a substantial likelihood that the
       contaminant will occur in public water systems with a frequency and at levels of public
       health concern; and
   •   In the sole judgment of the Administrator, regulation of such contaminant presents a
       meaningful opportunity for health risk reduction for persons served by public water
       systems.

Once contaminants have been placed on the CCL, EPA identifies if there are  any additional data
needs or if there are sufficient information to make  a regulatory determination. EPA interprets
these criteria for regulatory determination as  more rigorous than what is used to place
contaminants on the CCL.
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EPA developed a multi-step process, based on available data, to characterize occurrence and
adverse health risks a contaminant may pose to consumers of public water systems for inclusion
on the CCL. The steps involve:
    1)  Building a broad CCL Universe of potential drinking water contaminants for
       consideration
    2)  Using straightforward screening criteria related to a contaminant's potential to occur in
       drinking water and potential for public health concern to narrow the Universe to a
       Preliminary CCL (PCCL) (see "Final Contaminant Candidate List 3 Chemicals:
       Screening to a PCCL " (USEPA 2009a)), and;
    3)  Using a structured classification approach (e.g., a classification model) as a tool, along
       with expert judgment, to develop a proposed CCL from the PCCL (see "Final
       Contaminant Candidate List 3 Chemicals: Classification of the PCCL to the CCL "
       (USEPA 2009b)).
    4)  Providing opportunities for public comment and contaminant nomination (see "Summary
       of Nominations for the Third Contaminant Candidate List" (USEPA 2009c)).

The purpose of this document is to describe the process in the first step in which EPA: 1)
identified data resources for building the third Contaminant Candidate List (CCL 3) Chemical
Universe; and 2) assessed contaminant-specific information in these resources to identify over
6,000 contaminants for inclusion in the CCL 3 Universe.

In the first part of this effort, data sources were identified in the reports and recommendations of
the National Academy of Sciences' National Research Council (NRC, 2001), the National
Drinking Water Advisory Council (NOWAC, 2004), a stakeholder report (AWWA, 2003), and
EPA's  considerations of its statutory requirements. Through these reviews, 284 potential data
sources were identified that might provide relevant data to the CCL 3 process for drinking water.
These sources were reviewed for the purpose of compiling a Universe of chemicals for
consideration in the CCL 3 process, which will be discussed in Section 2. To evaluate the
usefulness of these 284 data sources, EPA developed and applied assessment criteria to select the
most appropriate data sources and identify contaminants for the CCL 3 Universe.
1.1 Background
The NRC report provided general guidance for a broad approach to collect extensive information
in building the CCL Universe that included using diverse data sources that provide contaminant
lists and large data sets of health effects, occurrence information, and chemical properties. The
NDWAC recommendations built on the NRC recommendations and  added more specific focus
and criteria to the process. NDWAC reviewed various approaches and recommended that a data
source compilation approach be used to aggregate on-line data sources. NDWAC noted that the
chemical CCL Universe should include those agents that have demonstrated or potential
occurrence in drinking water, or those agents that have demonstrated or potential adverse health
effects. To narrow the field of data sources compiled, NDWAC noted that the data and data
sources should have a reasonable link to adverse health effects and represent a reasonable
pathway to drinking water occurrence.
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NDWAC recognized that the data compilation for the CCL Universe should focus on readily
available data (e.g., automated retrieval) and that multiple sources may provide similar (or
identical) data. Not all sources contain data in a retrievable format; hence, some valuable sources
will need to serve as supplemental sources to fill in data gaps during the CCL process. NDWAC
also noted that the data compilation process should be supplemented with surveillance and
nomination processes to enable inclusion of new and emerging contaminants. Further, NDWAC
provided basic guidance to review the completeness of data source documentation and quality.

Potential data sources were identified and compiled through EPA research in support of the
NDWAC process and with a stakeholder workshop sponsored by the American Water Works
Association. Some preliminary evaluations and recommendations also resulted from the
workshop.  These efforts resulted in the listing of the 284 data sources that were assessed for the
CCL Universe.
1.2  Overview of the Data Source Assessment Factor Process
Exhibit 1 provides a schematic overview of the data source assessment process and the four
assessment factors: 1) Relevance, 2) Completeness, 3) Redundancy, and 4) Retrievability.

      Exhibit 1:  Flow Chart of the Data Source Assessment Process
                      CCL Universe- 284 Initial Data Sources
   Relevance - Does this data source contain demonstrated
   or potential health effects or occurrence or surrogate info?
                   Yes
                   (N=142)
     Completeness - Does this data source have the
  minimum record requirements - contact name, description
   of the data elements, and how the data were obtained?
                   Yes
                   (N=130)
  Redundancy - Does this data source contain information
      identical to other more comprehensive sources?
                   No
                   (N=104)
  Retrievability - Are the data in this source formatted for
             automated retrieval?
                                         No
                                         (N = 142)
                                         Yes
                                         01 = 26)
                        Not Used
                        for CCL 3
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Based upon EPA's statutory requirements and input from the NRC, NDWAC, and the
stakeholder process, EPA developed assessment factors to evaluate data sources to ensure they
are relevant to the CCL process, complete in basic documentation, not redundant with other data
sources, and are formatted for automated retrieval. These factors were based upon the NDWAC
recommendation that: data sources should have data and information about actual or potential
occurrence of contaminants in drinking water or source water and/or about health effects; the
CCL 3 Universe should focus on readily available data; and the sources should meet EPA's
minimum guidelines for documentation and quality.

Each source was accessed online (or as provided by the source proprietor) and reviewed; basic
information about the source, its purpose, and the data elements it contained, was compiled and
documented. Every source was evaluated using all assessment factors. Sources that "answered
yes" to the assessment factor questions in Exhibit 1 moved forward in the process. Those sources
that met all four factors became the prime sources that form the "Universe of Data Sources."
Some 67 data sources were not retrievable. Of these, 64 were utilized for supplemental analyses
at other stages of the classification process. Three of the  sources that were not retrievable were
also identified as "unique" or "exceptional" because of the importance of their data, and they
were also included in the Universe.

The 37 data sources that "answered yes" to all four assessment factors are listed in Exhibit 2. The
three unique and exceptional sources are identified in italics in the Exhibit. These are the 40  data
sources that comprised the starting point for the CCL 3 process. Each of these factors will be
discussed in more detail in Section 1.3.
     Exhibit 2: The Universe of Data Sources for the CCL 3 Process
      Name of Data Source
      Agency for Toxic Substances and Disease Registry (ATSDR) Comprehensive Environmental Response,
      Compensation, and Liability Act (CERCLA) Priority List
      ATSDR Minimal Risk Levels (MRLs)
      Chemical Toxicity Database - Ministry of Health and Welfare, Japan
      Chemical Update System/Inventory Update Rule (CUS/IUR) - EPA
      Cumulative Estimated Daily Intake/Acceptable Daily Intake (CEDI/ADI) Database - US Food and Drug
      Administration (FDA)
      Database of Sources of Environmental Releases of Dioxin-Like Compounds in the United States - EPA
      Distributed Structure Searchable Toxicity Public Database Network (DSSTox) - EPA
      Everything Added to Food in the United States (EAFUS) Database - FDA
      Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) List - EPA
  10
Generally Regarded As Safe (GRAS) Substance List - FDA
  11
Guidelines for Canadian Drinking Water Quality (CADW): Summary of Guidelines - Health Canada
  12
Hazardous Substances Data Bank (HSDB) - National Library of Medicine (NLM)
  13
Health Advisories (HA) Summary Tables - EPA
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      Name of Data Source
  14
High Production Volume (HPV) Chemical List - EPA
  15
Indirect Additives Database - FDA
  16
Information Collection Rule (ICR) Federal Database (DBF ICR) - EPA
  17
Integrated Risk Information System (IRIS) - EPA
  18
International Agency for Research on Cancer (IARC) Monographs
  19
International Toxicity Estimates for Risk (ITER) Database - Toxicology Excellence in Risk Assessment
(TERA)
  20
Joint Meeting On Pesticide Residues (JMPR) - 2001 Inventory of Pesticide Evaluations - World Health
Organization (WHO), Food and Agriculture Organization (FAO)
  21
National Drinking Water Contaminant Occurrence Database (NCOD) - Round 1&2 - EPA
  22
NCOD - Unregulated Contaminant Monitoring Regulation (UCMR) - EPA
  23
National Inorganics and Radionuclides Survey (NIRS) - EPA
  24
National Pesticide Use Database - National Center for Food and Agricultural Policy (NCFAP)
  25
National Reconnaissance of Emerging Contaminants (NREC) - United States Geological Survey (USGS)
Toxic Substances Hydrology Program
  26
National Toxicology Program (NTP) Studies
  27
National Water Quality Assessment (NAWQA) - USGS
  28
OSHA 1988 Permissible Exposure Limits (PELs) - National Institute for Occupational Safety and Health
(NIOSH)
  29
Pesticide Data Program (PDF) - United States Department of Agriculture (USD A)
  30
Pesticides Pilot Monitoring Program (PPMP) - USGS/EPA
  31
Risk Assessment Information System (RAIS) - Department of Energy - Chemical Factors
  32
RAIS - Department of Energy - Health Effects Data
  33
State of California Chemicals Known to the State to Cause Cancer or Reproductive Toxicity
  34
Substances Registry System (SRS) - EPA
  35
Syracuse Research Corporation (SRC) - BIODEG
  36
The Toxics Release Inventory (TRI) - EPA
  37
Toxic Substances Control Act (TSCA) List - EPA
  38
Toxicity Criteria Database - California Office of Environmental Health Hazard Assessment (OEHHA)
  39
University of Maryland - Partial List of Acute Toxins/Partial List of Teratogens
  40
WHO Guidelines for Drinking Water Quality: Summary Tables
1.3  Assessment Factors
In this section, the rationale for the four Assessment Factors is set out in more detail. Examples
are also provided to illustrate their application.
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1.3.1  Relevance
The Relevance assessment factor addresses the NOW AC and NRC principles for the CCL 3
Universe and evaluates whether a data source contains information on demonstrated or potential
occurrence of contaminants in the environment and/or demonstrated or potential human health
effects. Various surrogate data that may be used to evaluate potential occurrence are also
relevant. Some examples of relevant data sources include: International Toxicity Estimates for
Risk, which provides peer-reviewed toxicological  data (demonstrated health effects); the
Unregulated Contaminant Monitoring Regulation (UCMR), an EPA survey of unregulated
contaminants in drinking water, a source of data on demonstrated occurrence in drinking water;
and the National Water Quality Assessment program, a nation-wide water-quality sampling
program conducted by the United States Geological Survey (USGS) that provides demonstrated
occurrence in source waters or potential occurrence in drinking water. An example of a data
source that is not relevant to the CCL  process is the Label Review Manual. This is simply a
guidance manual for reviewing pesticide labels. It does not contain any occurrence or health
effects information or even lists of agents to consider. Other examples include data sources that
provide toxicological data for aquatic  macro-invertebrates but not data for mammalian or human
health effects. Such sources are not  relevant at this stage of the process.

Another example of sources that are not relevant to the CCL process is simple lists of chemicals
without any indication (or application) of potential health effects or occurrence in water (e.g., the
National Information Services Corporation Structure and Nomenclature System). However,
some sources that are lists of chemicals may also provide health effects or occurrence
information. If the purpose of the list is to identify an adverse health effect or the potential for
occurrence, these may be relevant. For example, a source that is a list of teratogens by its nature
includes information regarding potential adverse health effects, even though it may not contain
actual health effects data elements. Related to occurrence, the High Production Volume list is a
list of chemicals that are produced at greater than one million pounds per year, indicative of the
potential for occurrence in  the environment and drinking water.

Sources of information on physical/chemical properties that contain environmental fate data
(e.g., biodegradation rates) also may be useful surrogate information to indicate potential
occurrence and are considered relevant. However, sources that provide information only on
chemical properties that do not relate to environmental fate, such as the melting point for a
chemical, are considered not relevant.

Of the 284  data sources, 142 sources contain information relevant to the CCL 3 Universe, and
142 do not. Therefore, 142 sources moved forward into the next step  of the assessment.

1.3.2  Completeness
The Completeness assessment evaluates whether the data source provides complete, minimum
documentation and quality requirements. NOW AC recommended that each source should
include: 1)  provision of the name of a person to contact about the data source (or contact
information); 2) a description of the data elements; 3) information on how the data were
obtained; and 4) meaningfulness and relevance of the data. (The "meaningfulness and relevance"
NOW AC recommendation is addressed by the Relevance assessment factor,  so it is not included
in the Completeness assessment.) Also, data sources that provide documentation of peer review
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are considered to satisfy the Completeness criteria. NDWAC specifically recommended that an
assessment of individual data elements within the data sources was not appropriate at this stage
of the CCL process. A more in-depth assessment of data quality may occur at later stages of the
CCL process, before a final CCL 3 is produced.

An example of a data source that did not pass the Completeness assessment was the
Compendium of Common Pesticide Names, because there was no documentation readily
available for how the data were obtained or compiled. A few sources were eliminated because
they are proprietary and none of the documentation is publicly available. These sites would have
been eliminated in subsequent steps for other reasons, as well. (Similarly, some sources that did
not pass the Relevance evaluation would have been eliminated by the Completeness assessment.)

Of the 142 data sources that meet the Relevance criteria, 12 sources did not meet the
Completeness assessment factor.  These sources were not used to provide information to the
CCL 3 Universe.

1.3.3  Redundancy
The Redundancy assessment factor evaluates whether data sources contain  information that is
identical to (i.e., duplicates information from) other,  more comprehensive data sources. An
example of a redundant source would be data contained in a state or regional data source that
were copied from a more comprehensive or representative national data source. Therefore, to be
considered redundant, a data source must contain data identical with respect to the identity of the
original data gatherer, time, place, method, outcome, and data manipulation or modification. For
example, the same data gatherer might conduct a survey of the same size, taken in the same
places, processed according to the same methods, showing the same results and manipulated the
same way, yet it would not be redundant if the surveys were done at different times. Note that if
two sources provide identical data elements,  but one provides data for more contaminants, these
sources are considered Redundant, and the larger, more comprehensive, source is included.
Exceptions to this rule overlap  into the Retrievability factor: if the smaller source is retrievable,
but the larger source is not, the smaller source may be used in cases where the smaller source
contained all the relevant data.  For example,  EAFUS (Everything Added to Food in the United
States) and GRAS (Generally Regarded As Safe) are both part of the PAFA (Priority Based
Assessment of Food Additive Database). The data in EAFUS and GRAS are retrievable. PAFA
is a subscription source, and is  not retrievable. Further, EAFUS and GRAS  provide the relevant
information from PAFA,  so EAFUS  and GRAS were used, but PAFA was not.

Exhibit 3 shows a few examples of sources that met the Relevance and Completeness
Assessment Factors,  but were determined to be Redundant and thus were excluded from the
CCL 3 Universe. (All the sources, and their Assessment Factor evaluations are shown in
Appendix 1.) Of the 130 data sources that meet the Relevance and Completeness assessment
factors, 26 sources are Redundant and were not included in the CCL 3 Universe.
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        Exhibit 3: Examples of Retained and  Redundant Sources
       Source Retained For CCL 3
        Universe Consideration
  Source classified as Redundant
 (Excluded from CCL 3 Universe
        Consideration)
         Comments
   OSHA 1988 PELs
Idaho Toxic and Hazardous
Substances - Idaho Division of
Building Safety
OSHA (PELs) is more
comprehensive
   BIOLOG, BIODEG, CHEMFATE,
   and DATALOG - SRC
SRC - Environmental Fate Databases
(EFDB)
EFDB simply provides a link to, and
leads to, BIOLOG, BIODEG,
CHEMFATE, and DATALOG
   NCOD - Round 1&2 - EPA
Unregulated Contaminant
Information System (URCIS) - EPA
URCIS was converted into NCOD
Round 1 database, Therefore URCIS
is redundant to NCOD.
   IARC - Summaries and Evaluations
INTOX Databank - International
Programme on Chemical Safety
(IPCS)
INTOX is a subscription source and
IARC is independently and publicly
available. Therefore IARC was used
for the CCL process.
1.3.4  Retrievability
The Retrievability assessment factor is an evaluation of whether the data in a source are
formatted for automated retrieval. For example, if data are stored in a tabular format, they may
be extracted and formatted, using software tools, and imported directly into a database for further
use. In contrast, many data stored in a text format require manual review and interpretation prior
to extraction and may require manual input into the database.

However, data sources that consist of relevant simple lists in text format, that can be easily
retrieved, and can be imported are considered to be Retrievable. Some text sources present
occurrence and health effects data in consistent layouts (albeit in paragraph style) and some use
suitable formats (i.e., HTML) and retrieval can be automated in some of these cases for select
data. This has been accomplished for some key sources (e.g., the Hazardous Substances Data
Bank (HSDB)) for a limited number of contaminants.

There are some unique considerations for the retrievability of some CCL data sources. For
example, the Storage and Retrieval System (STORET) is an EPA data warehouse from which the
data are readily retrievable. However, many data fields in STORET are highly variable to
accommodate the many original sources of data that STORET captures. STORET data are often
not nationally representative and the data often overlap with nationally representative water data
such as NAWQA. The data also provide results based on different analytical methods and study
goals, and these data in aggregate will require additional evaluation and documentation related to
their inclusion in STORET. Based on these special processing and analysis requirements,
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STORET is designated as a supplemental source to be used in the next level of CCL 3
evaluations.

Another factor limiting the retrievability of many sources is that they are not readily available
publicly. NDWAC expressed concern for transparency and for the ability of the public to review
the types of data used in the CCL 3 process. Many sources require a subscription and this may
limit public access. Sources that were identified as subscription sources, i.e., sources that would
require payment for use, were classified as not Retrievable as they are not readily accessible to
the public.

Of the 104  data sources that are Relevant,  Complete and not Redundant, 67 sources do not meet
the Retrievability assessment factor. Data from sources that meet the Relevance, Completeness
and Redundancy assessment factors, but not the Retrievability factor, may be important to fill
gaps in the  compilation process, and their data were utilized in later steps in the CCL 3 process.
Hence, these sources are designated as Supplemental sources and are described in the next
section. Also, as noted earlier in this report, 3 of the 67 sources that were not retrievable, were
considered  unique and exceptional and were added to the Universe data sources (see Exhibits 1
and 2), leaving 64 sources reserved as Supplemental.

After analyzing the initial 284 data sources for relevance, completeness, redundancy and
retrievability, we are left with 40 data sources in our "Universe of Data Sources." This includes
the three unique or exceptional data sources not meeting the retrievability criterion.
1.4 Supplemental Data Sources
As noted in Section 2, the sources that meet all of the assessment factors except for
Retrievability are considered supplemental sources that may be used to provide data at other
steps in the CCL 3  process. For example, in the Universe to the Preliminary CCL 3 (PCCL 3)
screening process, it may prove worthwhile to consult a toxicological summary such as the
Registry of Toxic Effects of Chemical Substances (RTECS) to obtain data not already available
in the Universe database from a retrievable source for particular contaminants. Exhibit 4 lists the
64 Supplemental data sources.  Sources that are not retrievable because they require a
subscription (11) are identified in the second section of the Exhibit.

The 284 data sources also include a number of bibliographic sources (bibliographic search
engines) that were not classed as relevant to the Universe data compilation step of the CCL 3.
This is because they consist of text (titles and/or abstracts) on many subjects not pertaining to
CCL, and what data they may contain are inconsistently presented. These are partly retrievability
issues as well. However, depending on the data needs at various points in the CCL 3 process,
such bibliographic  sources and search engines (i.e., "PubMed", Science Direct) were used to fill
in data gaps in the screening and classification processes. A total of 35 supplemental sources
were utilized in other stages of the CCL 3 classification process and are identified in italics in
Exhibit 4.
                                       Page 9 of 18

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EPA-OGWDW                         Final CCL 3 Chemicals:                      EPA 815-R-09-006
                                     Identifying the Universe                           August 2009

  Exhibit 4:  Supplemental Sources that Meet the Assessment Factors
 of Relevance, Redundancy, and Completeness, but not Retrievability
           Supplemental Sources that Meet the Assessment Factors of Relevance, Redundancy,
                              and Completeness, but not Retrievability
  1
     1 Oth Report on Carcinogens - NTP
  2
Alternate Crops and Systems (ARS) Pesticide Properties Database - USDA
  3
A TSDR Internet HazDat - Site Contaminant Query
  4
A TSDR Toxicological Profiles
  5
California Department of Pesticide Regulation (CDPR)
  6
Chemical Carcinogenesis Research Information System (CCRIS) - NLM
  7
Comprehensive Environmental Response, Compensation, and Liability Information System (CERCLIS) -EPA
     Concise International Chemical Assessment Documents (CICADs) - IPCS, WHO, International Labor
     Organization (ILO), United Nations Environmental Programme (UNEP)
  9
EC Water Directive - European Community
 10
Endocrine Disrupter Priority Setting Database - EPA
 11
Environmental Monitoring and Assessment Program (EMAP) - EPA
 12
Genetic Activity Profiles (GAP) Database - EPA
 13
GENE-TOX-NLM
 14
Guidelines for Canadian Drinking Water Quality (CADW): Supporting Documentation - Health Canada
 15
Health Advisory Documents - EPA
 16
Health and Safety Guides - WHO, ILO, UNEP, Canadian Center for Occupational Health and Safety
(CCOHS)
 17
Health Effects Assessment Summary Tables (HEAST) -EPA, National Center for Environment Assessment
(NCEA)
 18
High Production Volume (HPV) Challenge Program Robust Summaries and Test Plans - EPA
 19
Human Exposure Database System (HEDS) - EPA
 20
International Register of Potentially Toxic Chemicals (IRPTC PC) - Data Profiles - UNEP Chemicals
 21
Joint Expert Committee on Food Additives (JECFA) -Monographs and Evaluations - WHO, FAO
 22
Joint Meeting On Pesticide Residues (JMPR) -Monographs of Toxicological Endpoints- WHO, FAO
 23
Laboratory Chemical Safety Summaries (LCSS) - Howard Hughes Medical Institute and National Academies
of Sciences (NAS)
 24
National Health and Nutrition Examination Survey (NHANES) - Centers for Disease Control and Prevention
(CDC)
 25
National Human Adipose Tissue Survey (NHATS) -EPA
 26
National Institute for Occupational Safety and Health (NIOSH) - Index of Occupational Health Guidelines for
Chemical Hazards
 27
National Occupational Exposure Survey (NOES) - CDC
 28
National Sediment Inventory (NSI) - EPA
 29
National Toxicology Program (NTP) Health and Safety Profiles
 30
Office of Pollution Prevention and Toxics (OPPT) Chemical Fact Sheets - EPA
 31
Organization for Economic Co-operation and Development (OECD) Integrated HPV Database
 32
Permit Compliance System (PCS) Database - EPA
 33
Persistent, Bio accumulative, and Toxic Profiler (PBT Profiler) - EPA
 34
Pesticide Action Network (PAN) Pesticide Database
 35
Pesticide Handler Exposure Database - EPA
                                          Page 10 of 18

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EPA-OGWDW                         Final CCL 3 Chemicals:                     EPA 815-R-09-006
                                     Identifying the Universe                          August 2009
           Supplemental Sources that Meet the Assessment Factors of Relevance, Redundancy,
                             and Completeness, but not Retrievability
 36  Pesticide Product Information System (PPIS) - EPA
 37
Pesticides Tolerance Index System - EPA
 38
Priority Substances Assessment Program - Health Canada
 39
Registry of Toxic Effects of Chemical Substances (RTECS)
 40
Reregistration Eligibility Decision Documents (REDDs) - EPA Office of Pesticide Programs (OPP)
 41
Rijksinstituut voor Volksgesondheid en Milieu (RIVM) Maximum Permissible Risks (MPRs) Report
 42
Safe Drinking Water Information System (SDWIS) - EPA
 43
Screening Information Data Sets (SIDS) - OECD
 44
Source Ranking Database (SRD) - EPA
 45
State Drinking Water Data Sets - EPA
 46
State of New Jersey Hazardous Substances Right to Know Fact Sheets
 47
STORET - STORage and RETrieval - EPA
 48
Superfund Contract Laboratory Program (SCLP) Water/Soil Data - EPA
 49
Total Exposure Assessment Methodology Study (TEAM) - EPA
 50
Toxic Substances Control Act Test Submissions (TSCATS) - EPA
 51
US Army Center for Health Promotion and Medicine Detailed Chemical Fact Sheets
 52
WHO Guidelines for Drinking Water Quality: Chemical Aspects: Index of Chemicals
 53  WHO Recommended Classification of Pesticides by Hazard (CPH)
Subscription Sources
  1
Chemical Evaluation Search and Retrieval System (CESARS) - CCOHS
  2
CrossFire BEILSTEIN - MDL Information Systems
  3
Derek - LHASA Limited
  4
Dictionary of Substances and Their Effects - Knovel
  5
National Sanitary Foundation (NSF) -Additives Standards 60 and 61
  6
Palm Top Emergency Action for Chemicals (PEAC-CW System) - Federal Technical Support Working
Group
     Priority-based Assessment of Food Additives (PAFA) Database - FDA
     STN - CHEMLIST/HCHEMLIST - Regulated Chemical Listing
  9
The Open Practical Knowledge Acquisition Toolkit (TOPKAT) - Accelrys
 10
TOMES PLUS, MICROMEDEX - Thomson-Micromedex
 11
Water Environment Research Foundation (WERF) Toxicity Datasheets
1.5 Additional Information
A detailed summary of the assessment process for the 284 sources is presented in the appendices
to this report. There are four appendices that summarize information about the data sources and
the assessment process. Appendix 1 is a list of the 284 sources along with notes discussing
whether the source satisfies the four assessment factors, and, if not, why not. Appendix 2
provides summary information about the data sources that meet all of the assessment factors and
that will populate the CCL 3 Universe. Appendix 3 shows supplemental data sources that met the
first three requirements, but were not considered readily retrievable. Appendix 4 includes more
descriptive information about the purpose and scope of the 284 data sources, and provides
                                          Page 11 of 18

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EPA-OGWDW                       Final CCL 3 Chemicals:                    EPA 815-R-09-006
                                  Identifying the Universe                        August 2009


background information for each source, including details on the source proprietor, a description
of the source, the format of the source, and the data elements included in each.
2.0  The CCL 3 Chemical Universe Selection Process
The purpose of this section is to describe the decision process that EPA used to develop the
Universe of chemicals identified from the 40 data sources (the "Universe of Data Sources")
selected, as described in Section 1. The data sources, classified by whether they provided
occurrence or health effects data, produced a compilation of 25,980 unique substances. Because
of the large number of substances, EPA developed a pre-Universe selection process that is
described in the following sections.

Exhibits 5 and 7 provide schematic diagrams that depict the two phases of the selection process
for the "Universe of Chemicals." The selection process represented in Exhibit 5 generated an
initial compilation of the Chemical Universe, but included some substances that were not unique
chemicals because they were mixtures, water soluble ions that are redundant to contaminants
already under consideration, or different valence states of the same element. Accordingly, the
process represented by Exhibit 7 was used to refine the initial compilation and generate the final
CCL 3 Universe of Chemicals.
2.1  Chemicals in Occurrence and Health Effects Sources
The first stage in the process, as illustrated in Exhibit 5, identified approximately 7,300
chemicals that were present in both health effects and occurrence data sources. These chemicals
were automatically placed in the preliminary Chemical Universe to be further evaluated for
screening to the PCCL 3. Since only about 1/3 of the chemicals were in both health effects and
occurrence data sources, the rest of the approximately 18,600 chemicals left in the pre-Universe
were examined more closely to determine whether they were found only in health effects data
sources or only in occurrence data sources.
2.2 Chemicals in Health Effects Sources Only
Approximately 5,100 chemicals were in health effects data sources only. Many of these
chemicals were biochemical compounds (e.g. amino acids, sugars, steroids); mixtures and
natural products (e.g. coal tar, petroleum related substances, rocks, stone, wool); and other
entries that were identified as unique "substances" in the data sources but were not chemicals
(e.g. turbidity, boot and shoe manufacture, surgical implants). Once the chemicals were
categorized and evaluated, EPA placed the chemicals of greatest toxicological concern in the
CCL 3 Chemical Universe, even though there was no known link to occurrence information. The
criteria for selecting contaminants that are of greatest toxicological concern are described in
detail in the EPA CCL 3 report entitled, "Final Contaminant Candidate List 3 Chemicals:
Screening to a PCCL" (USEPA, 2009a). Many chemicals fell in this category because of their
classification as potential carcinogens. A total of 122 chemicals were added to the initial version
of the CCL 3 Chemical Universe through this process.
                                      Page 12 of 18

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EPA-OGWDW
                           Final CCL 3 Chemicals:
                           Identifying the Universe
EPA815-R-09-006
     August 2009
     Exhibit 5:  Overview of Data Evaluation for the CCL 3 Universe
                                  Selection Process
              CCL Universe of Chemicals - Evaluation of Chemical Occurrence and Health
                                       Effects Data
         Universe of Data Sources
      # of Unique Chemicals = 25,980
                Is the chemical round in an occurrence
                       and HE source?
                   Chemicals in HE sources
                          5,107
                                    Is the Chemical of Toxicological Concern
                Chemicals in Occurrence sources
                         13,544
                                                             Chemicals Not
                                                               Added to
                                                               Universe
                                                                 (18,260)
  Is it found
n a finished water
or ambient water
   source?
                     No/  Is it found  N.  No / Is it produced
                        in a release data /~*\in amounts > 1 bil.
                           source?   /   \ Ibs/yean
2.3 Chemicals in Occurrence Sources Only
The chemicals found only in occurrence sources were also categorized. The approximately
13,500 chemicals with only occurrence data are a diverse group, comprised of many different
types of chemicals. Production data sources account for 70% of the total, and others are from
various finished water, ambient water, environmental release, environmental property, and food
additive data sources.
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EPA-OGWDW
Final CCL 3 Chemicals:
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EPA815-R-09-006
     August 2009
Exhibit 5 also shows several groups of chemicals that were added to the Universe of chemicals
even though the data sources lacked information on health effects. These included the following
groupings:

   •  Chemicals with Finished or Ambient Water Data
   •  Chemicals with Release Data
   •  Chemicals with High Production Volumes

Examples of key types of chemicals with only occurrence data are shown in Exhibit 6. The
chemicals with finished or ambient water data (42) were added to the Universe despite the lack
of health effects information in the data sources because of their demonstrated occurrence in
ambient or potable water. In addition, disinfection byproducts (e.g., from EPA's DSSTox DBF
lists) and water treatment additives (e.g., National Sanitary Foundation (NSF) Standard 60) were
added to the Chemical Universe. While these chemicals may not have demonstrated occurrence
data in the Universe of Data Sources, they are considered to have "default" occurrence data
because they are formed in, or intentionally added to, drinking water supplies.
  Exhibit 6:  Example of Universe Contaminants with Occurrence Data
                           but no Health Effects Data
Occurrence Data
Type
Finished and Ambient
Water data
Environmental Release
Production
Listed as food additive or only on
list with general physical or
chemicals properties
Type of Data; Typical Source
Measured Water Occurrence;
UCMR, NAWQA
Amount Released; TRI, Pesticide
Application
Annual Production Volume;
CUS/IUR
Generally Regarded as Safe Substance
List (FDA); RAIS (DOE)
Number of
Chemicals
Without Health
Effects
42
36
9,344
4,122
The 36 chemicals with an environmental release data source (e.g., those on the Toxics Release
Inventory or with pesticide application data) were also added to the Universe of chemicals.
Thirty-six chemicals met this criterion and were added to the CCL 3 Chemical Universe.

Of the approximately 9,400 chemicals with only production information, only  191 were
produced in extremely high volumes (greater the 1 billion pounds per year). The 9,400
contaminants with production data consist of the following types: organometallics, elements,
non-elemental inorganics, salts of organic acids, organics (including: oils, fatty acids, dyes), and
mixtures (petroleum related compounds, hydrocarbons, and others). Many are predominantly
organic components and salts of organic acids, and over half of the chemicals are complexes of
                                      Page 14 of 18

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EPA-OGWDW                       Final CCL 3 Chemicals:                    EPA 815-R-09-006
                                  Identifying the Universe                         August 2009

elemental constituents. For example, there were about 750 sodium or potassium salt compounds
alone. In these cases, health effects data are not available for the exact compound, but are
generally available for other related compounds or the key ion or elemental constituent (e.g.,
sodium). Nearly all elements found in inorganic or organic salts are represented in the Universe
by other compounds with both health effects and occurrence data. Only 10 elements (excluding
the obvious, such as hydrogen and oxygen, and the inert gasses krypton, neon, and xenon) did
not otherwise have representative compounds with health effects data in the universe. EPA added
europium, gadolinium, gold, lanthanum, praseodymium, platinum, polonium, samarium,
terbium, and yttrium to the Universe. After consideration of the diversity of the chemicals with
production data and the amounts produced on a yearly basis, a decision was made to move only
those produced at greater than 1 billion pounds per year to the CCL 3 Chemical  Universe.

The rest of the substances with occurrence data only, in the original data sources, were not
included in the Universe. This included 4,122 substances primarily from lists of miscellaneous
food additives and some from lists that only provided simple physical or chemical properties,
could not be linked to any health effects data.

After examining the data on the chemicals with only occurrence data, a total of 269 additional
chemicals were added to the CCL 3  Chemical Universe. As noted, the rest of the substances
included in the original data sources were not included in the Universe.
2.4 Refining the Initial Universe of Chemicals
The initial selection process described in Exhibit 5 brought into the CCL 3 Universe of
Chemicals all substances from the data sources that met the defined selection criteria. This
included regulated as well as unregulated compounds, mixtures, and some substances that were
not really chemicals. Accordingly the process diagrammed in Exhibit 7 was used to refine the
initial list.

The first step in the refinement process was to remove chemicals with a National Primary
Drinking Water Regulation. These contaminants are already regulated; thus, their inclusion in the
CCL process is clearly unnecessary. This step removes a large number of chemicals (1,009),
more than the number covered by the primary standards, because of the form of the chemicals in
the compilation. For example, the chemicals removed include approximately 780 radionuclides
that are regulated as alpha and beta emitters, many redundant ionic and valence state entries for
elements and inorganic chemicals, and entries for individual polychlorinated biphenyls (PCBs)
that are regulated as total PCBs.

The second step was to remove substances that are considered a mixture of chemicals. A mixture
in this case is defined as a combination of two or more  chemicals/items that are not defined as a
unique substance. Substances that fell  in this category included "chlorinated compounds,
alcohols c>14, coal-tar-containing shampoo, petroleum-related substances, resin acids, rosin
acids, and guar gum," for example. Undefined mixtures, such as "diesel engine exhaust" were
also included in this group.
                                       Page 15 of 18

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 EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
 The third step removed "non-chemically defined" entries from the initial list. Examples of the
 type of items in this category include: "solar radiation, wood dust, surgical implants, and welding
 fumes." Some of these substances are present in the data sources because they have been
 evaluated for their potential to cause cancer.
            Exhibit 7:  Overview of Data Evaluation for the CCL 3
                                   Universe Selection
                 CCL Universe of Chem icals - Refinement of Initial Compilation
            Does the contaminant have an NPDWR?
                                           Yes = 1,009*
                N o = 6,711
         Isthe contaminant part a mixture of chemicals?
                                            Yes = 430
                No= 6,281
          Is the contaminant non-chemically defined?
                                            Yes = 276
                No =6,00 5
               Isthe contaminant biological?
                                            Yes =2
                No= 6,003
                                                              CCL 3 Universe
                                                                  of
                                                                Chemicals
* Includes ~780 radionuclides that are regulated as alpha and beta emitters, many redundant ionic and valence state entries for
elements and inorganic chemicals, and entries for individual PCBs that are regulated as total PCBs.
 The final step removed biological agents from the initial list. Contaminants in this category are
 biological organisms that are being evaluated as part of the CCL 3 Microbiological Universe.
 Entries for biological entities were uploaded from the Universe of data sources from various
 health effects data sources and pesticide data sources. (Many biological entities were removed as
 non-chemically defined,  as well.)

 After applying the process shown in Exhibit 7,  1,717 chemicals or substances were removed
 from the initial Chemical Universe leaving approximately 6,000 chemicals to be evaluated. EPA
 also published a Federal Register announcement requesting nominations from the public for
                                          Page 16 of 18

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EPA-OGWDW                      Final CCL 3 Chemicals:                    EPA 815-R-09-006
                                 Identifying the Universe                        August 2009

chemical and microbial contaminants that should be considered for CCL 3. The Agency received
information from 11 organizations and individuals on 174 nominated contaminants that included
150 chemical and 24 microbial contaminants. The Agency was already considering 132 of these
contaminants in the CCL 3 process. EPA processed the nominated contaminants through the
same steps used for the other contaminants considered for the draft CCL 3. Nominated
contaminants that were regulated or did not meet any of the other decision criteria for the
universe were not added to the CCL 3 Universe.

The draft CCL 3 was published on February 21, 2008 (73 FR 9628, USEPA 2008). EPA
provided information and sought comment on the draft list, its efforts to expand and strengthen
the underlying CCL listing process, and EPA's efforts to  improve the contaminant selection
process for future CCLs.

EPA received comments from 177 individuals or organizations on the draft CCL  3. Commenters
provided information and recommendations for the Agency to consider as it finalized the CCL 3.
The Agency has provided responses to individual comments in the "Comment Response
Document for the Third Drinking Water  Contaminant Candidate List (Categorized Public
Comments) " document that is available in the regulatory docket at regulations.gov. (USEPA
2009d). The EPA SAB and its Drinking Water Committee also reviewed the draft CCL 3 during
2008, and provided an Advisory to the EPA Administrator (USEPA 2009e).

EPA evaluated all the data and information on chemical contaminants provided by commenters
and collected by the Agency after the draft CCL 3 was published. EPA used the same process
described in this and other support documents noted (and in the draft CCL 3 notice, 73 FR 9628,
USEPA 2008) to evaluate contaminants for which data became available after the publication of
the draft CCL 3 (see USEPA 2009b). The Agency added 30 contaminants to the Universe,
adjusted the contaminants that passed through to the PCCL based on these new data and
reevaluated the PCCL using the CCL 3 protocols as described. The list of contaminants included
in the CCL 3 Universe is presented in Appendix 5. The Appendix presents the contaminants in
order of their CASRN, indicates the contaminant's progression through the CCL  3 process, and
if the contaminant was on CCL 1 or CCL 2.
3.0  References

AWWA. 2003. CCL Workshop Report - Review of the Information Resources. June 2003.

NDWAC. 2004. National Drinking Water Advisory Council Report on the CCL Classification
       Process to the U.S. Environmental Protection Agency. May 19, 2004

NRC. 2001. Classifying Drinking Water Contaminants for Regulatory Consideration. National
       Academies Press. Washington. DC.

USEPA. 2008. Drinking Water Contaminant Candidate List 3 - Draft Notice. Federal Register.
       Vol. 72. No. 35. p.9628. February 21, 2008.
                                      Page 17 of 18

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EPA-OGWDW                     Final CCL 3 Chemicals:                  EPA 815-R-09-006
                               Identifying the Universe                      August 2009


USEPA. 2009a. Final Contaminant Candidate List 3 Chemicals: Screening to a PCCL. EPA 815-
      R-09-007. August 2009.

USEPA. 2009b. Final Contaminant Candidate List 3 Chemicals: Classification of PCCL to the
   CCL. EPA 815-R-09-008. August 2009.

USEPA. 2009c. Summary of Nominations for the Third Contaminant Candidate List. EPA-815-
   R-09-01 I.August 2009.

USEPA. 2009d. Final Comment Response Document for the Third Drinking Water Contaminant
      Candidate List (Categorized Public Comments). EPA 815-R-09-010. August 2009.

USEPA. 2009e. SAB Advisory on EPA's Draft Third Drinking Water Contaminant Candidate
      List (CCL 3). EPA-SAB-09-011. January 2009.
4.0 Appendices

Appendix 1. CCL 3 All Data Sources - Assessment Table
   Appendix 1 provides a listing of the 284 data sources and notations indicating whether a
source satisfied the four assessment factors and, if not, which factors were not satisfied and why.


Appendix 2. CCL 3 Universe of Data Sources
   Appendix 2 provides a summary of information about the 40 data sources that met the
assessment factors, or were deemed unique and exceptional, and that were used to populate the
CCL 3 Universe.
Appendix 3. CCL 3 Universe Supplemental Data Sources
   Appendix 3 shows the supplemental data sources that met the first three assessment factors
but contained data not considered readily retrievable. While not used for compiling the Universe,
these data sources were used to supplement contaminant evaluations during stages of the CCL
process.


Appendix 4. CCL 3 Data Source Descriptions
   Appendix 4 includes descriptive information about each of the data sources.


Appendix 5. CCL 3 Universe Chemicals
   Appendix 5 includes the list of the chemicals in the CCL 3 Universe, their CASRNs and
indicators of their status in the CCL 3 process.
                                   Page 18 of 18

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EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID
1

2

4
3
5
9

6

Data Source Name
10th Report on Carcinogens -
NTP

8(e) TRIAGE Chemical Studies
Database - OPPT

Aerometric Information Retrieval
System/Air Quality Subsystem
(AIRS/AQS)
AGRICultural OnLine Access
(AGRICOLA)
All the Virology on the WWW
Alternate Crops and Systems
(ARS) Pesticide Properties
Database

Analytical ABSTRacts
(ANABSTR)

Assessment Factor Evaluation
	 c
v K a
S % "-











Meets
Relevance
X



X


X



8.1
|1
d) re
•Ji Q.
rv x
V- uj
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
information on air emissions, which
may indicate potential occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
information on persistence, that may
be used as an indicator of potential
occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
Meets
Redundancy
X

X


X
X
X

X

>> c
s-l
•81
ll
"8 §-
OL UJ
This source is not redundant.

This source is not redundant.

This source is redundant with Idaho
Toxic and Hazardous Substances -
Idaho Division of Building Safety
(source 100).
This source is redundant with
Cambridge Scientific Abstracts
(source 15), but that source is a
subscription, whereas this source is
free of charge.
This source is not redundant.
This source is not redundant.

This source is not redundant.

Meets
Completeness
X

X

X
X

X

X

Documentation
of
Peer Review
Y

Unknown

Y
Y
N
Y

Unknown

il|
Y

Y

Y
Y
N
Y

Y

Meets
Retrievability




X






& £
1= 0
!5 '*=
1 g
5! ra
!5 a.
IS x
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

                                                                    A1-1

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID

7

8

10

11


12


13

123

Data Source Name

Aquatic Pollution and
Environmental Quality -
Cambridge Scientific Abstracts

AQUatic toxicity Information
Retrieval (AQUIRE)

ASFA 3: Aquatic Pollution and
Environmental Quality -
Cambridge Scientific Abstracts

Assessment Tools for the
Evaluation of Risk (ASTER)


ATSDR CERCLA Priority List


ATSDR Internet HazDat - Site
Contaminant Query

ATSDR Minimal Risk Levels
(MRLs)

Assessment Factor Evaluation
Meets All
Assessment
Factors










X




X

Meets
Relevance










X


X

X

8.1
|1
Si ra
•Ji Q.
rv x
01 LU
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it only contains
information on ecological toxicity.
This source is considered relevant for
the CCL Universe because the basis
for developing this list is ATSDR's
prioritization of chemicals found at
NPL sites and that ATSDR believes
may pose a human health risk.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements (MRL) derived from
toxicological studies.
Meets
Redundancy

X





X


X


X

X

>> c
s-l
Is
If
•§ §-
o: LU

This source is not redundant.

This source is redundant with
ECOTOX (source 57).

This source is identical to Aquatic
Pollution and Environmental Quality
- Cambridge Scientific Abstracts
(source 7).

This source is not redundant.


This source is not redundant.


This source is not redundant.
These data are also represented in
the ATSDR Toxicological Profiles;
however, these data are tabular
while the Profiles are monographic.
Meets
Completeness

X

X

X

X


X


X

X

Documentation
of
Peer Review

N

Y

N

Unknown


Y


Unknown

Y

Meets All
NDWAC
Requirements

Y

Y

Y

Y


Y


Y

Y

Meets
Retrievability







X


X




X

& c
1= 0
!5 '*=
1 g
5! _re
IS x
OL "J

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source meets retrievability criteria
because it is in tabular format.


This source meets retrievability criteria
because it is in tabular format.


This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.

This source meets retrievability criteria
because it is in tabular format.

                                                                    A1-2

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID

210
243

14

15
16
272

17

Data Source Name

ATSDR Toxicological Profiles
AwwaRF Project Reports

Bad Bug Book

Base de Dados Tropical (BDT)
Sergey's Manual of Systematic
Bacteriology
Biennial Reporting System

BIOBUSINESS Biological
Abstracts Database

Assessment Factor Evaluation
a! K re
S % "-












Meets
Relevance

X










8.1
|1
d) (0
£ X
^ UJ
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies and information on production,
which may indicate potential
occurrence.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
Meets
Redundancy

X
X



X
X
X

X

>> c
s-l
•81
if
0) X
o; uj

This source is not redundant.
This source is not redundant.

This source is one of the sources
administered by CSFAN (source
231).

This source is not redundant.
This source is not redundant.
This source is not redundant.

This source is not redundant.

Meets
Completeness

X
X

X

X
X
X

X

Documentation
of
Peer Review

Y
Y

Unknown

N
Y
Unknown

Y

il|

Y
Y

Y

Y
Y
Y

Y

Meets
Retrievability












& £
1= 0
!5 '*=
1 g
5! ra
£ o.
fll X
OL UJ

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria because it is only available
through a subscription.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

                                                                    A1-3

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID

18


19


20


21


235


22


23

Data Source Name

Biological Sciences - Cambridge
Scientific Abstracts


BIOSIS Biological Abstracts and
BIOSIS Previews


Bugs


CAB Abstracts - CABI Publishing


California Department of Pesticide
Regulation (CDPR)


CANCERLIT


Carcinogenic Potency Project
(CPP)

Assessment Factor Evaluation
Meets All
Assessment
Factors





















Meets
Relevance













X





X

8.1
11
Si ra
•Ji Q.
rv x
01 LU
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.

This source is considered relevant for
the CCL Universe because it contains
a list of bioactive compounds.

This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
data on carcinogenicity from
toxicological studies.
Meets
Redundancy

X


X


X


X


X


X




>> c
s-l
Is
If
•§ §-
o: LU

This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is redundant with
DSSTox (source 53).

Meets
Completeness

X


X


X


X


X


X


X

Documentation
of
Peer Review

N


N


Unknown


N


Y


Y


Y

Meets All
NDWAC
Requirements

Y


Y


Y


Y


Y


Y


Y

Meets
Retrievability







X











X

& c
1= 0
!5 '*=
1 g
5! _re
IS x
OL "J

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source meets retrievability criteria
because it is in tabular format.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source meets retrievability criteria
because it is in tabular format.

                                                                    A1-4

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID
238
231
29
30
24
28
285
36
42
Data Source Name
Case/MCase/MC4PC
Center for Food Safety and
Applied Nutrition (CFSAN)
Chemfinder
Chemical Backgrounder
Chemical Carcinogenesis
Research Information System
(CCRIS)
Chemical Evaluation Search and
Retrieval (CESARS) - CCOHS
Chemical Hazard Response
Information System
Chemical Information System
(CIS) - ILO/OSHIC
Chemical Registry System (CRS)
Assessment Factor Evaluation
a! K re
S % "-









Meets
Relevance
X


X
X
X


X
8.1
|1
d) re
•Ji Q.
rv x
V- uj
This source is considered relevant for
the CCL Universe because it could be
a source of information on potential
health effects.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source is considered relevant for
the CCL Universe because it contains
inhalation exposure limits, which may
provide information on potential health
effects.
This source is considered relevant for
the CCL Universe because it contains
the results of carcinogenicity and
mutagenicity studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source is no longer available
online.
This source is considered relevant for
the CCL Universe because it is an
interface to other information in EPA's
SRS system.
Meets
Redundancy
X
X
X
X
X
X
X


>> c
s-l
•81
It
£ UJ
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is no longer available
online.
This source is redundant, as it is
wholly available as part of
Substance Registry System (SRS)
(source 203).
Meets
Completeness

X
X

X
X


X
Documentation
of
Peer Review
Unknown
Y
Unknown
N
Y
Y
Unknown
Unknown
Y
il|
N
Y
Y
N
Y
Y
N
NA
Y
Meets
Retrievability








X
& £
1= 0
!5 '*=
1 g
v _re
d) X
This source does not meet retrievability
criteria. The source does not contain
data; it is a model that might be used to
generate estimates. The source is only
available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source is no longer available online.
This source meets retrievability criteria
because it is in tabular format.
                                                                    A1-5

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification

ID
31
32

33

283


34



37


25


245


Data Source Name
Chemical Toxicity Database -
Ministry of Health and Welfare,
Japan
Chemical Update System (CUS)

Chemical Update
System/Inventory Update Rule
(CUS/IUR)

Chemicals in Commerce
Information System (CICIS) -
Toxic Substances Control Act
Inventory


ChemlDplus - Chemical



Clinical Virology


Communicable Disease Report
(CDR) - United Kingdom


Communicable Disease Reports
(CDR) - Australia

Assessment Factor Evaluation
5 | £
« tn 2
•£ .
o
a |
Ji
1
X


X




X



X


X


X

>> c
s-l
2 re
1 <=
It
Q: UJ
This source is not redundant.
This source is redundant with
CUS/IUR (source 33).

This source is not redundant.

The source is redundant with
TSCA.


This source is not redundant.



This source is not redundant.


This source is not redundant.


This source is not redundant.

to
8
J2 v
82
Sf
o
O
X
X

X

X


X



X







° 9
IS 1
s >
Documer
of
Peer Re
Y
Unknown

Unknown

Unknown


Y



Y


Unknown


Unknown

3g|
Is *
01 9 =
" J
Y
N

Y

Y


Y



Y


N


N

&
£ 1
a! Z
l|
1
X


X
















& £
1= 0
% re
re re
d) Co
E g-
OL "J
This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval. This
source is retrievable through CUS/IUR.

This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

                                                                    A1-6

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID
255

38


276

35

27


39



41

26

44

Data Source Name
Compendium of Pesticide
Common Names
Comprehensive Environmental
Response, Compensation, and
Liability Information System
(CERCLIS)

Computer Retrieval of Information
on Scientific Projects

Concise International Chemical
Assessment Documents (CICADs)
Contaminant Exposure and
Effects - Terrestrial Vertebrates
(CEE-TV) Database

Control of Communicable
Diseases Manual; 17 ed.



CrossFire BEILSTEIN

Cumulative Estimated Daily
Intake/Acceptable Daily Intake
(CEDI/ADI) Database

Current Contents Search - Life
Sciences - ISI

Assessment Factor Evaluation
Meets All
Assessment
Factors


















X



Meets
Relevance
X

X




X








X

X



8.1
|1
Si ra
•Ji Q.
rv x
01 LU
This source is considered relevant for
the CCL Universe because it contains
a list of bioactive compounds.
This source is considered relevant for
the CCL Universe because it contains
information on potential contaminant
occurrence at superfund sites.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it contains only
information on ecological toxicity.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies and environmental fate data,
providing an indicator of potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
health effects data.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
Meets
Redundancy
X

X


X

X

X


X



X

X

X

>> c
s-l
Is
If
•§ §-
o: LU
This source is not redundant.

This source is not redundant.


This source is not redundant.

This source is not redundant.

This source is not redundant.


This source is not redundant.



This source is not redundant.

This source is not redundant.

This source is not redundant.

Meets
Completeness


X




X

X


X



X

X



Documentation
of
Peer Review
Unknown

Y


Unknown

Y

N


Y



Y

Y

N

Meets All
NDWAC
Requirements
N

Y


N

Y

Y


Y



Y

Y

N

Meets
Retrievability
X

















X



& c
1= 0
!5 '*=
1 g
5! _re
IS x
OL "J
This source meets retrievability criteria
because it is in HTML format and can be
extracted in tabular format.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

                                                                    A1-7

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification

ID



46

241


48


47


49

51

45


Data Source Name


Database of Sources of
Environmental Releases of Dioxin-
Like Compounds in the United
States
Derek


Derwent Crop Protection File
(Derwent CROPU)


Derwent Crop Registry File
(Derwent CROPR)


Derwent Drug File (Derwent
DRUGU)

Design Institute for Physical
Property Data (DIPPR)

Developmental and Reproductive
Toxicology/Environmental
Teratology Information Center
(DART®/ETIC) Database

Assessment Factor Evaluation
5 | £
« tn 2
8 $ re
1 %"-
<

X
















HI
u
•& £
|5
&


X

X














8.1
ID _re
OL x
"- UJ
This source is considered relevant for
the CCL Universe because it contains
information on air emissions, which
may indicate potential occurrence.
This source is considered relevant for
the CCL Universe because it could be
a source of information on potential
health effects

This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
>.
u
a |
li
IK
OL

X

X


X


X


X

X

X

>> c
s-l
2 re
1 <=
1 3
"§ X
Q: UJ

This source is not redundant.

This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is not redundant.

This source is not redundant.

This source is not redundant.

to
8
16 v
8 2
5 o.
E E
O

X

X


X


X


X

X

X

° 9
« 1
| o n:
0 »
8 °-

Y

Unknown


Unknown


Unknown


Unknown

Y

Y

3g|
Is *
at Q '5
^z y
u.

Y

Y


Y


Y


Y

Y

Y

&
£ 1
a! Z
£ 5
a!
£

X
















& £
1= 0
% re
re re
d) Co
- 8-
OL UJ

This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria. The source does not contain
data; it is a model that might be used to
generate estimates. The source is only
available through a subscription.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because it is only available
through a subscription.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

                                                                    A1-8

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID
50
53
52
242
256
56
57
63
Data Source Name
Dictionary of Substances and
Their Effects - Knovel
Distributed Structure Searchable
Toxicity Public Database Network
(DSSTox)
Division of Bacterial and Mycotic
Diseases (DBMD) - Disease
Information Listing
EC Water Directive
Ecological Incident Information
System
Ecology of Aquatic Hyphomycetes
ECOTOX - A Database of Toxic
Effects to Aquatic and Terrestrial
Species
Elsevier BIOBASE
Assessment Factor Evaluation
a! K re
S % "-

X






Meets
Relevance
X
X

X




8.1
|1
Si re
•5 a.
°- Ml
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
regulatory limits for contaminants in
drinking water.
This source does not meet relevance
criteria because it contains only
information on ecological toxicity.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it contains only
information on ecological toxicity.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
Meets
Redundancy
X
X
X
X
X
X
X
X
>> c
s-l
•81
ll
"8 §-
OL w
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
X
X
Documentation
of
Peer Review
Y
Unknown
Y
Unknown
Unknown
Y
Y
Y
il|
Y
Y
Y
Y
Y
Y
Y
Y
Meets
Retrievability

X


X



& £
1= 0
!5 '*=
1 g
5! ra
!5 a.
IS x
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
                                                                    A1-9

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID

65


59


68


60


58


258

61
Data Source Name

EMBASE


Endocrine Disrupter Priority
Setting Database (EDPSD)


Environmental Abstracts -
LexisNexis Academic and Library
Solutions


Environmental Data Registry
(EDR)


Environmental Defense Fund
(EOF) Chemical Profiles


Environmental Fate Databases

Environmental Health Criteria
(EHC) Monographs
Assessment Factor Evaluation
Meets All
Assessment
Factors



















Meets
Relevance




X








X


X

X
8.1
|1
Si ra
•Ji Q.
rv x
01 LU
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
data elements derived from
toxicological studies and unique
elements derived for measurements of
contaminants in water, providing an
indicator of occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.

This source is considered relevant for
the CCL Universe because it contains
information on potential health effects.


This source is considered relevant for
the CCL Universe because it contains
environmental fate data, providing an
indicator of occurrence.

This source is considered relevant for
the CCL Universe because it contains
data elements (LDx, LO(A)EL,
NO(A)EL) from toxicological studies.
Meets
Redundancy

X


X


X


X


X





>> c
s-l
Is
If
•§ §-
o: LU

This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is not redundant.

This source is redundant with
BIOLOG, BIODEG, CHEMFATE,
and DATLOG. EFDB simply
provides a link to, and leads to,
BIOLOG, BIODEG, CHEMFATE,
and DATALOG.
This source is redundant, as it is
wholly available as part of INTOX
(source 105).
Meets
Completeness

X


X





X





X

X
Documentation
of
Peer Review

Y


N


N


N


N


Unknown

Y
Meets All
NDWAC
Requirements

Y


Y


N


Y


N


Y

Y
Meets
Retrievability



















& c
1= 0
!5 '*=
1 g
5! _re
IS x
OL "J

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
                                                                    A1-10

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification

ID



62


64


67


66

69
70

71


Data Source Name



Environmental Information
Management System (EIMS)


Environmental Monitoring and
Assessment Program (EMAP)


Environmental Monitoring
Methods Index (EMMI)


Environmental Mutagen
Information Center Database
(EMIC)

Environmental Pollution - Elsevier
Science
Environmental Science and
Technology

Environmental Sciences and
Pollution Management -
Cambridge Scientific Abstracts

Assessment Factor Evaluation
5 | £
« tn 2
8 $ re
1 %"-
<

















HI
u
•& £
|5
&





X












8.1
ID _re
OL x
"- UJ
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source is considered relevant
because it contains geographical and
water quality data, providing an
indicator of potential occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
>.
u
a |
li
IK
OL

X


X


X


X

X
X

X

>> c
s-l
2 re
1 <=
1 3
"§ X
Q: UJ

This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is not redundant.

This source is not redundant.
This source is not redundant.

This source is not redundant.

to
8
16 v
8 2
5 o.
E E
O

X


X


X


X

X
X

X

° 9
« 1
| o n:
0 »
8 °-

Y


Y


Y


Y

Y
Y

N

3g|
Is *
at Q '5
^z y
u.

Y


Y


Y


Y

Y
Y

Y

&
£ 1
a! Z
£ 5
a!
£

X















& £
1= 0
% re
re re
d) Co
- 8-
OL UJ

This source meets retrievability criteria
because it is in tabular format.

Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.

This source does not meet retrievability
criteria because it is only available
through a subscription.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

                                                                    A1-11

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID
55
72
54
73
274
289
263
75
74
Data Source Name
European Inventory of Existing
Commercial Substances
(EINECS) Information System
Eurosurveillance
Everything Added to Food in the
United States (EAFUS) Database
Extension TOXicology NETwork
(EXTOXNET)
Facilities Index Data System
Federal Insecticide, Fungicide,
and Rodenticide Act (FIFRA) List
Food Commodity Intake Database
Food Quality Protection Act
(FQPA) - "Cumulative to
Pesticides" List
FoodNet
Assessment Factor Evaluation
	 c
v K a
S % "-


X


X



Meets
Relevance


X
X

X

X

8.1
|1
Si re
% *
"• w
This source does not meet relevance
criteria because it contains a chemical
list that is not related to health effects
or occurrence.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals that is related to
potential exposure.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals that is related to
potential exposure.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals that is related to
their toxicity/health effects.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
Meets
Redundancy
X
X
X
X
X
X
X

X
>> c
s-l
•81
ll
"8 §-
OL w
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is redundant with the
list of contaminants in FIFRA.
This source is not redundant.
Meets
Completeness

X
X


X

X
X
Documentation
of
Peer Review
N
Y
Y
N
Unknown
Unknown
N
Unknown
Y
il|
N
Y
Y
N
N
Y
N
Y
Y
Meets
Retrievability


X


X

X

& £
1= 0
!5 '*=
1 g
5! ra
!5 a.
IS x
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source meets retrievability criteria
because it is accessible through EPA's
Substance Registry System.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
                                                                    A1-12

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID


277



77

81

76



78


79

80


82

Data Source Name


Gastrointestinal Absorption
Database



GenBank® - National Center for
Biotechnology Information

Generally Regarded As Safe
(GRAS) Substance List

Genetic Activity Profiles (GAP)
Database



GENE-TOX


Genomes and Databases

Global Infectious Disease and
Epidemiology Network (GIDEON)


Ground Water On-Line - National
Ground Water Association

Assessment Factor Evaluation
Meets All
Assessment
Factors








X















Meets
Relevance








X

X



X









8.1
|1
Si ra
•Ji Q.
rv x
01 LU
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals that is related to
their toxicity/health effects.
This source is considered relevant for
the CCL Universe because it contains
information on mutagenicity, which
may be an indicator of potential health
effects.
This source is considered relevant for
the CCL Universe because it contains
information on mutagenicity, which
may be an indicator of potential health
effects.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
Meets
Redundancy


X



X

X

X



X


X

X


X

>> c
s-l
Is
If
•§ §-
o: LU


This source is not redundant.



This source is not redundant.

This source is not redundant.

This source is not redundant.



This source is not redundant.


This source is not redundant.

This source is not redundant.


This source is not redundant.

Meets
Completeness






X

X

X



X




X


X

Documentation
of
Peer Review


Unknown



Y

Y

Y



Y


N

Unknown


N

Meets All
NDWAC
Requirements


N



Y

Y

Y



Y


N

Y


Y

Meets
Retrievability








X















& c
1= 0
!5 '*=
1 g
v _re
IS x
OL "J

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.

This source has been withdrawn; it is no
longer available online.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

                                                                    A1-13

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID
83
84


95

87
88
89
91

90


94
Data Source Name
Guidelines for Canadian Drinking
Water Quality (CADW): Summary
of Guidelines
Guidelines for Canadian Drinking
Water Quality (CADW):
Supporting Documentation


Hazardous Substances Data Bank
(HSDB)

Health Advisories (HA) Summary
Tables - EPA
Health Advisory Documents
Health and Safety Guides - World
Health Organization, ILO, UNEP,
CCOHS
Health Effects Assessment
Summary Tables (HEAST) - EPA
NCEA

Healthlnsite


High Production Volume (HPV)
Challenge Program Robust
Summaries and Test Plans
Assessment Factor Evaluation
	 c
v K a
S % "-
X



X

X








Meets
Relevance
X
X


X

X
X
X
X




X
8.1
|1
Si re
•5 a.
°- Ml
This source is considered relevant for
the CCL Universe because it contains
data elements (ADI, NO(A)EL) from
toxicological studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.

This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements (RfDs) from
toxicological studies.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies and environmental fate data,
providing an indicator of potential
occurrence.
Meets
Redundancy
X
X


X

X
X
X
X

X


X
>> c
s-l
•81
ll
"8 §-
OL w
This source is not redundant.
This source is not redundant.


This source is not redundant.

This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.

This source is not redundant.


This source is not redundant.
Meets
Completeness
X
X


X

X
X
X
X




X
Documentation
of
Peer Review
Y
Y


Y

Y
Y
Y
Y

N


N
il|
Y
Y


Y

Y
Y
Y
Y

N


Y
Meets
Retrievability
X





X








& £
1= 0
!5 '*=
1 g
5! ra
!5 a.
IS x
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
The list of contaminants in HSDB is
retrievable. The data are not formatted
for automated retrieval. The HSDB is a
unique and exceptional source and is
included to supplement the CCL
Universe.

This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
                                                                   A1-14

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID

93
92

100

101


102

103
98
270
Data Source Name

High Production Volume (HPV)
Chemical List
Human Exposure Database
System (HEDS)

Idaho Toxic and Hazardous
Substances - Idaho Division of
Building Safety

Incidence and Prevalence
Database (IPD) - Timely Data
Resources


Indirect Additives Database

Infectious Disease Information
Information Collection Rule (ICR)
Federal Database
Information System for Hazardous
Organics in Water
Assessment Factor Evaluation
	 c
v K a
S % "-

X







X




Meets
Relevance

X
X

X




X


X

8.1
|1
Si re
•5 a.
°- Ml
This source is considered relevant for
the CCL Universe because it is a list
and contains information on production
volume, which may indicate potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
information that is related to potential
exposure.
This source is considered relevant for
the CCL Universe because it contains
inhalation exposure limits, which may
provide information on potential health
effects.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals that is related to
potential exposure.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
Meets
Redundancy

X
X



X


X

X
X
X
>> c
s-l
•81
ll
"8 §-
OL w

This source is not redundant.
This source is not redundant.

This source is redundant with
OSHA PELs (source 234), which is
a more comprehensive source.

This source is not redundant.


This source is not redundant.

This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness

X
X

X

X


X

X
X

Documentation
of
Peer Review

Y
N

Unknown

N


Y

N
Y
Unknown
il|

Y
Y

Y

Y


Y

Y
Y
N
Meets
Retrievability

X


X




X


Y

& £
1= 0
!5 '*=
1 g
5! ra
!5 a.
IS x

This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.

This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
Data are retrievable by EPA. They may
require special processing for analysis
for CCL use.
This source does not meet retrievability
criteria because it is only available
through a subscription.
                                                                    A1-15

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID

108


104

204

96


97


99


43

Data Source Name

Integrated Risk Information
System (IRIS)


Integrated Taxonomy Information
System

International Agency for Research
on Cancer (IARC) - Summaries
and Evaluations

International Agency for Research
on Cancer (IARC) Monographs


International Bibliographic
Information on Dietary
Supplements (IBIDS) - NIH


International Chemical Safety
Cards (ICSCs) - IPCS/WHO/ILO


International Cosmetic Legal and
Regulatory Database - The
Cosmetic, Toiletry, and Fragrance
Association (CTFA)

Assessment Factor Evaluation
Meets All
Assessment
Factors

X






X










Meets
Relevance

X




X

X





X




8.1
|1
Si ra
•Ji Q.
rv x
01 LU

This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.

This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
data elements directly from and
derived from toxicological studies.

This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.

This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
inhalation exposure limits, which may
provide information on potential health
effects.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
Meets
Redundancy

X


X



X


X





X

>> c
s-l
Is
If
•§ §-
o: LU
The toxicological data for this
source are available in tabular
format from ITER (#110) and RAIS-
Health Effects (#178). Hence there
is some overlap and redundancy,
but each also provide additional
information not available elsewhere.

This source is not redundant.

This source is redundant, as it is
wholly available as part of INTOX
(source 105).

This source is not redundant.


This source is not redundant.


This source is redundant, as it is
wholly available as part of INTOX
(source 105).


This source is not redundant.

Meets
Completeness

X


X

X

X


X


X




Documentation
of
Peer Review

Y


Y

Y

Y


Y


Y


N

Meets All
NDWAC
Requirements

Y


Y

Y

Y


Y


Y


N

Meets
Retrievability

X


X














& c
1= 0
!5 '*=
1 g
5! _re
IS x
OL "J
This source contains monographs that
were not formatted for automated
retrieval. However, the toxicological data
from this source have been compiled for
electronic retrieval in ITER, and were
obtained from there. IRIS monographs
were used to confirm the

This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
The monographic information in this
source is not retrievable; however, the
list of contaminants and their cancer
groups is retrievable and will be used for
the CCL Universe. IARC is a unique and
exceptional source and is included to
supplement the CCL U

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because it is only available
through a subscription.

                                                                    A1-16

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification

ID


106

109


110

105
107
111
112


113
264

Data Source Name


International Pharmaceutical
Abstracts (I PA)

International Register of
Potentially Toxic Chemicals
(IRPTC PC) - Data Profiles -
UNEP Chemicals


International Toxicity Estimates for
Risk (ITER) Database

INTOX Databank - IPCS
IPCS/EC Evaluation of Antidote
Series
Joint Expert Committee on Food
Additives (JECFA) - Monographs
and Evaluations
Joint Meeting On Pesticide
Residues (JMPR) - 2001 Inventory
of Pesticide Evaluations

Joint Meeting On Pesticide
Residues (JMPR) - Monographs
of Toxicological Endpoints
Label Review Manual
Assessment Factor Evaluation
= 1 .
v K a
^ in






X




X




HI
u
+2 c
Jj
*



X


X

X
X
X
X


X

8.1
11
Si re
•Ji Q.
n- x
01 w
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies and environmental fate data,
providing an indicator of potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements directly from and
derived from toxicological studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements derived from

toxicological studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
u
c
I !
IE =
&

X

X


X



X
X


X
X
>> c
go
si
il
£ UJ

This source is not redundant.

This source is not redundant.


This source is not redundant.

This source is redundant with IARC
Summaries and Evaluations.
INTOX is a subscription source and
IARC is independently and publicly
available.
This source is redundant, as it is
wholly available as part of INTOX
(source 105).
This source is not redundant.
This source is not redundant.


This source is not redundant.
This source is not redundant.
in
in
HI
a jj
5 ~°-
O
O

X

X


X

X
X
X
X


X
X
° 9
"5 a)
C ,. 0)
* o Q:
3 0)
g £.

N

Y


Y

Y
Y
Y
Y


Y
Unknown
1
ill
K

Y

Y


Y

Y
Y
Y
Y


Y
Y
t
M S2
o! Z
l|
£






X




X




& £
1= 0
1 g
v _re
d) X

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.


This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
                                                                    A1-17

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID
114
115
286
116
124
117
278
118
119
Data Source Name
Laboratory Chemical Safety
Summaries (LCSS) - Howard
Hughes Medical Institute and
National Academy of Science
List of Bacterial Names with
Standing in Nomenclature
Mallinckrodt Baker, Inc., Material
Safety Data Sheets
Master Summary Table for HPV
Chemical Hazard Data Availability
Study
Material Safety Data Sheets
(MSDS)
Mediscover
MEDLINE
Michigan State Ribosomal
Database Project
Microbe Library
Assessment Factor Evaluation
a! K re
S % "-









Meets
Relevance
X

X
X





8.1
|1
Si re
•5 a.
°- Ml
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
environmental fate data, that may be
used as an indicator of potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
a list that is related to occurrence.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
Meets
Redundancy
X
X
X

X
X
X
X
X
>> c
s-l
•81
ll
"8 §-
OL w
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is redundant, as it is
wholly available as part of the HPV
Chemical List (source 93) and
CUS/IUR (source 33).
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X

X
X
X
X
X
X
Documentation
of
Peer Review
Y
N
Unknown
N
Y
Y
N
Y
Y
il|
Y
Y
N
Y
Y
Y
Y
Y
Y
Meets
Retrievability



X



X

& £
1= 0
!5 '*=
1 g
5! ra
!5 a.
IS x
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
                                                                    A1-18

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID
120
121
122
239
125
127
126
135
Data Source Name
Microbiology Abstracts, Section B:
Bacteriology - Cambridge
Scientific Abstracts
MicrobioNet
Morbidity and Mortality Weekly
Report (MMWR) Surveillance for
Waterborne-Disease Outbreaks
Multicase
Municipal Water Use Database -
Environment Canada
National Ambulatory Medical Care
Survey (NAMCS)
National Animal Health Reporting
System (NAHRS)
National Cancer Institute
Database of 3 Dimensional
Chemical Structures (NCI-3D)
Assessment Factor Evaluation
a! K re
S % "-








Meets
Relevance



X




8.1
|1
Si re
•5 a.
°- Ml
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it could be
a source of information on potential
health effects.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source does not meet relevance
criteria because it contains only
information on microbial contaminants.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
Meets
Redundancy
X
X


X

X
X
>> c
s-l
•81
ll
"8 §-
OL w
This source is not redundant.
This source is not redundant.
This source is redundant with
FoodNet (source 74).
This source is redundant, as it is
the same as the Case model
(source 238).
This source is not redundant.
This source is redundant, as it is
wholly available as part of IPD
(source 101).
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X

X
X
X
X
Documentation
of
Peer Review
N
Y
Y
Unknown
Unknown
Y
Unknown
Unknown
il|
y
Y
Y
N
Y
Y
Y
Y
Meets
Retrievability







X
& £
1= 0
!5 '*=
1 g
5! ra
!5 a.
IS x
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria. The source does not contain
data; it is a model that might be used to
generate estimates. The source is only
available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
                                                                    A1-19

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID
136

137


233


129


139


141


140

Data Source Name
National Drinking Water
Contaminant Occurrence
Database (NCOD) - 6-Year Data

National Drinking Water
Contaminant Occurrence
Database (NCOD) - Round 1&2

National Drinking Water
Contaminant Occurrence
Database (NCOD) - Unregulated
Contaminant Monitoring Rule
(UCMR)

National Environmental Data
Index (NEDI)


National Health and Nutrition
Examination Survey (NHANES)


National Hospital Discharge
Survey (NHDS)


National Human Adipose Tissue
Survey (NHATS)

Assessment Factor Evaluation
Meets All
Assessment
Factors


X


X













Meets
Relevance


X


X





X


X


X

8.1
|1
Si ra
•Ji Q.
rv x
01 LU
This source does not meet relevance
criteria because it contains only
information for regulated
contaminants.
This source is considered relevant for
the CCL Universe because it contains
measurements of unregulated
contaminants in drinking water,
demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
drinking water, demonstrating
occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
either the blood or urine, providing an
indicator of occurrence.
This source is considered relevant for
the CCL Universe because it contains
information on prescribed medications.
These data might be used as a source
of information on potential occurrence
of Pharmaceuticals.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
human adipose tissue, providing an
indicator of occurrence.
Meets
Redundancy
X

X


X


X


X





X

>> c
s-l
Is
If
•§ §-
o: LU
This source is not redundant.

This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is redundant, as it is
wholly available as part of IPD
(source 101).


This source is not redundant.

Meets
Completeness
X

X


X


X


X


X


X

Documentation
of
Peer Review
Y

Y


N


N


Y


Y


Y

Meets All
NDWAC
Requirements
Y

Y


Y


Y


Y


Y


Y

Meets
Retrievability
X

X


X













& c
1= 0
!5 '*=
1 g
v _re
IS x
OL "J
This source meets retrievability criteria
because it is in tabular format.

This source meets retrievability criteria
because it is in tabular format.


This source meets retrievability criteria
because it is in tabular format.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

                                                                    A1-20

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID
249
144
143
142
145
130
131
146
Data Source Name
National Human Exposure
Assessment Survey (NHEXAS)
National Inorganics and
Radionuclides Survey (NIRS)
National Institute for Occupational
Safety and Health (NIOSH) -
Index of Occupational Health
Guidelines for Chemical Hazards
National Institute of Enviornmental
Health Sciences (NIEHS)
Reproductive Toxicology Group
National Nosocomial Infections
Surveillance System (NNIS)
National Notifiable Diseases
Surveillance System
National Notifiable Diseases
Surveillance System (Australia)
National Occupational Exposure
Survey (NOES)
Assessment Factor Evaluation
	 c
v K a
S % "-

X






Meets
Relevance
X
X
X




X
8.1
|1
Si re
•5 a.
°- Ml
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
information that is related to potential
exposure.
Meets
Redundancy

X
X
X
X
X
X
X
>> c
s-l
•81
ll
"8 §-
OL w
This source is redundant, as it is
wholly available as part of HEDS
(source 92).
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
X
X
X
X
Documentation
of
Peer Review
Y
Y
Y
Y
Y
Y
Unknown
Y
il|
Y
Y
Y
Y
Y
Y
Y
Y
Meets
Retrievability
X
X

X


X

& £
1= 0
!5 '*=
1 g
5! ra
!5 a.
IS x
This source meets retrievability criteria
because it is in tabular format.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval,
however some tabular data have been
obtained from ERG.
                                                                    A1-21

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID

261


128
132

147

148

149
133
150
Data Source Name

National Pesticide Information
Retrieval System


National Pesticide Use Database
National Reconnaissance of
Emerging Contaminants (NREC) -
USGS Toxic Substances
Hydrology Program

National Research Council (NRC)
Publications

National Sanitary Foundation
(NSF) - Additives Standards 60
and 61

National Sediment Inventory (NSI)
National Stream Quality
Accounting Network (NASQAN)
National Toxicology Program
(NTP) Health and Safety Profiles
Assessment Factor Evaluation
	 c
v K a
S % "-




X
X








Meets
Relevance




X
X



X

X
X
X
8.1
|1
Si re
•5 a.
°- Ml
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
information on pesticide use, an
indicator of potential occurrence.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
information on health effects standards
for drinking water.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
sediments (which can contribute
contaminants to drinking water), and
can indicate potential occurrence.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
Meets
Redundancy




X
X

X

X

X

X
>> c
s-l
•81
ll
"8 §-
OL w
This source is redundant with the
Pesticide Data Submitters' List, the
Pesticide Product Information
Database, and the Pesticide
Tolerance Index.

This source is not redundant.
This source is not redundant.

This source is not redundant.

This source is not redundant.

This source is not redundant.
This source is redundant with
NAWQA.
This source is not redundant.
Meets
Completeness

X


X
X

X

X

X
X
X
Documentation
of
Peer Review

Unknown


Unknown
Y

Y

Y

N
Y
Y
il|

Y


Y
Y

Y

Y

Y
Y
Y
Meets
Retrievability




X
X






X

& £
1= 0
!5 '*=
1 g
5! ra
!5 a.
IS x

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source meets retrievability criteria
because it is in tabular format.
This source meets retrievability criteria
because USGS provided the data
directly to EPA in a useable format.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
                                                                    A1-22

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID

248

151
134

279

155
244

156

287
Data Source Name

National Toxicology Program
(NTP) Studies

National Water Information
System (NWIS Web)
National Water Quality
Assessment (NAWQA)

NIOSHTIC

Office International des Epizooties
(OIE) Handistatus II
Office Internationales Epizooties

Office of Pollution Prevention and
Toxics (OPPT) Chemical Fact
Sheets

Oil and Hazardous
Materials/Technical Assistance
Data System
Assessment Factor Evaluation
Meets All
Assessment
Factors

X


X









Meets
Relevance

X

X
X






X

X
S|
d) (3
"Ji Q.
rv x
01 w
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies and environmental fate data,
providing an indicator of potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
environmental fate data, that may be
used as an indicator of potential
occurrence.
Meets
Redundancy

X


X

X

X


X

X
>> c
s-l
Is
It
o: uj

This source is not redundant.

This source is redundant with
NAWQA.
This source is not redundant.

This source is not redundant.

This source is not redundant.
This source is identical to Office
International des Epizooties (OIE)
Handistatus II (source 155).

This source is not redundant.

This source is not redundant.
Meets
Completeness

X

X
X

X




X


Documentation
of
Peer Review

Y

Y
Y

Unknown

N
Unknown

N

Unknown
Meets All
NDWAC
Requirements

Y

Y
Y

Y

N
N

Y

N
Meets
Retrievability



X
X



X
X




& £
1= 0
11
d) Co
E g-
OL "J
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval. NTP
studies provide unique and exceptional
data and are included to supplement the
CCL Universe.

This source meets retrievability criteria
because it is in tabular format.
This source meets retrievability criteria
because USGS provided the data
directly to EPA in a useable format.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.

This source meets retrievability criteria
because it is in tabular format.
This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because it is only available
through a subscription.
                                                                    A1-23

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification

ID

237


152


234

163
158

161


160


159



Data Source Name

Oncologic


Organisation for Economic Co-
operation and Development
(OECD) Integrated HPV Database


OSHA 1988 Permissible Exposure
Limits (PELs)

Palm Top Emergency Action for
Chemicals (PEAC-CW System) -
Federal Technical Support
Working Group
Pan American Health
Organization (PAHO)
Communicable Disease

Permit Compliance System (PCS)
Database


Persistent, Bioaccumulative, and
Toxic Profiles (PBT Profiler)


Pesticide Action Network (PAN)
Pesticide Database

Assessment Factor Evaluation
	 c
v K a
^ in






X













HI
u
+2 c
Jj
*
X


X


X

X


X


X


X


8.1
11
Si re
•Ji Q.
n- x
01 w
This source is considered relevant for
the CCL Universe because it could be
a source of information on potential
health effects

This source is considered relevant for
the CCL Universe because it is a list of
HPV chemicals, which may indicate
possible occurrence. It also contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
inhalation exposure limits, which may
provide information on potential health
effects.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
information on discharge of waste to
rivers, which may indicate potential
occurrence.
This source is considered relevant for
the CCL Universe because it could be
a source of information on persistence,
providing an indicator of occurrence.

This source is considered relevant for
the CCL Universe because it contains
health effects data.

u
c
I !
IE =
&
X


X


X

X
X

X


X


X


>> c
go
si
ll
a: m
This source is not redundant.


This source is not redundant.


This source is not redundant.

This source is not redundant.
This source is not redundant.

This source is not redundant.


This source is not redundant.


This source is not redundant.


m
m
HI
a jj
5 ~°-
o
O



X


X

X
X

X


X


X


° 9
"5 a)
C ,. 0)
* o Q:
3 0)
g £.
Unknown


Y


Y

N
Unknown

Y


N


N


1
ill
i
N


Y


Y

Y
Y

Y


Y


Y


t
M S2
o! Z
l|
£






X













£" c
•— o
1 g
v _re
d) X
This source does not meet retrievability
criteria. The source does not contain
data; it is a model that might be used to
generate estimates. The source is only
available through a subscription.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.

This source does not meet retrievability
criteria. The source does not contain
data; it is a model that might be used to
generate estimates.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.
                                                                    A1-24

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID

265

162
266
257

262

168

267

268
269

259

Data Source Name

Pesticide Data Program

Pesticide Data Sheets (PDS) -
WHO, FAO
Pesticide Data Submitters List
(PDSL)
Pesticide Ecotoxicity Database

Pesticide Handler Exposure
Database

Pesticide Product Information
System (PPIS)

Pesticide Product Label System
(PPLS)

Pesticide Products Databases
Pesticide Tolerance Index System
(TISInfo)

Pesticides Ground and Surface
Water Incident Database

Assessment Factor Evaluation
Meets All
Assessment
Factors

X
















Meets
Relevance

X

X



X

X



X
X

X

S|
d) (3
"Ji Q.
rv x
01 w
This source is considered relevant for
the CCL Universe because it contains
measurements of pesticide residues,
an indicator of potential occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it contains a chemical
list that is not related to health effects
or occurrence.
This source does not meet relevance
criteria because it contains only
information on ecological toxicity.
This source is considered relevant for
the CCL Universe because it contains
information on human exposure to
pesticides.
This source is considered relevant for
the CCL Universe because it contains
an indicator of possible health effects.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source is considered relevant for
the CCL Universe because it contains
a list of contaminants with possible
health effects.
This source is considered relevant for
the CCL Universe because it contains
information on pesticide exposure
tolerances.
This source is considered relevant for
the CCL Universe because it is being
designed to contain information on
pesticide occurrence in water, an
indicator of occurrence.
Meets
Redundancy

X


X
X

X

X

X


X



>> c
s-l
Is
It
o: uj

This source is not redundant.

This source is redundant, as it is
wholly available as part of INTOX
(source 105).
This source is redundant with
NPIRS (source 261); however,
NPIRS is a subscription source.
This source is not redundant.

This source is not redundant.

This source is redundant with
NPIRS (source 261); however,
NPIRS is a subscription source.

This source is not redundant.

This source is redundant with
FIFRA.
This source is redundant with
NPIRS (source 261); however,
NPIRS is a subscription source.

This source has been withdrawn; it
is no longer available online.

Meets
Completeness

X

X
X
X

X

X

X

X
X



Documentation
of
Peer Review

Unknown

Y
Unknown
Y

Unknown

Unknown

Unknown

Unknown
Unknown

Unknown

Meets All
NDWAC
Requirements

Y

Y
Y
Y

Y

Y

Y

Y
Y

N

Meets
Retrievability

X



X







X




& £
1= 0
11
d) Co
E g-
OL "J

This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.

This source has been withdrawn; it is no
longer available online.

                                                                    A1-25

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification

ID



260

164
280
165

166


167


169


170
157

Data Source Name



Pesticides in Ground and Surface
Water Database

Pesticides Pilot Monitoring
Program - USGS/EPA
Plant Toxicity Data
Poisons Information Monographs
(PIMs) - IPCS, CCOHS

POLLUAB - Pollution Abstracts


Pollution Prevention Research
and Development Database -
EnviroNET Australia


Preliminary Remediation Goals
(PRGs) - EPA Region 9

Priority Substances Assessment
Program - Health Canada
Priority-based Assessment of
Food Additives (PAFA) Database
Assessment Factor Evaluation
= 1 .

s % "-
"*



X














HI
u
+2 c
Is
$


x

x

X







x


X
X
8.1
|1
Si re
0) 0.
°- w
This source is considered relevant for
the CCL Universe because it is being
designed to contain information on
pesticide occurrence in water, an
indicator of occurrence.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source does not meet relevance
criteria because it contains only
information on plant toxicity.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
data elements derived from
toxicological studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements directly from and
derived from toxicological studies.
u
c
j2 re
tu -o
HI c
g 3

OL



X



X


X





X
X
>> c
go
si
il
•§ §-
£ UJ

This source has been withdrawn; it
is no longer available online.

This source is not redundant.
This source is redundant with
ECOTOX (source 57).
This source is redundant, as it is
wholly available as part of INTOX
(source 105).

This source is not redundant.


This source is not redundant.


The relevant data in this source are
redundant with ITER and IRIS.

This source is not redundant.
This source is not redundant.
to
to
HI
a jj
^ "5.
E
O



X

X

X





x


X
X
° 9
"5 *
1 o a-

Q °"

Unknown

Y
Unknown
Y

Y


Unknown


Y


Y
Y
1
III
S z f
*

N

Y
N
Y

Y


N


Y


Y
Y
t
a! Z
jt 5
a!
K



X









x




& £
1= 0
1 g
5! ra
'i a.
IS x


This source has been withdrawn; it is no
longer available online.

This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because it is only available
through a subscription.
                                                                    A1-26

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID
171
172
173
180
176
275
179
177
178
Data Source Name
Program for Monitoring Emerging
Disease (ProMED)
PubMed
PulseNet: The National Molecular
Subtyping Network for Food borne
Disease Surveillance
Registry of Toxic Effects of
Chemical Substances (RTECS)
Reregistration Eligibility Decision
Documents (REDDs) - EPA OPP
Resource Conservation and
Recovery Information System
Rijksinstituut voor
Volksgesondheid en Milieu (RIVM)
Maximum Permissible Risks
(MPRs) Report
Risk Assessment Information
System (RAIS) - Department of
Energy - Chemical Factors
Risk Assessment Information
System (RAIS) - Department of
Energy - Health Effects Data
Assessment Factor Evaluation
a! K re
S % "-







X
X
Meets
Relevance



X
X

X
X
X
8.1
|1
Si re
•Ji Q.
rv x
01 w
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it does not contain
health effects or occurrence data or
information.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
radioactive half-life data, providing an
indicator of occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements directly from and
derived from toxicological studies.
Meets
Redundancy
X
X
X
X
X
X
X
X
X
>> c
s-l
•81
It
£ UJ
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.
Meets
Completeness
X
X
X
X
X

X
X
X
Documentation
of
Peer Review
Y
Y
Y
Y
Y
Unknown
Y
Y
Y
a:
Y
Y
Y
Y
Y
N
Y
Y
Y
Meets
Retrievability







X
X
& £
1= 0
!5 '*=
1 g
33 JS
dj X
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
This source meets retrievability criteria
because the relevant data can be
extracted in tabular format.
                                                                    A1-27

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID

175

281

232
182
183
189


190

191
Data Source Name

Risk Based Concentrations
(RBCs) - EPA Region 3

RISKLINE

Safe Drinking Water Information
System (SDWIS)
Screening Information Data Sets
(SIDS) - Organisation for
Economic Co-operation and
Development (OECD)
SOLV-DB
Source Ranking Database (3RD)


State Drinking Water Data Sets

State of California EPA Chemicals
Known to the State to Cause
Cancer or Reproductive Toxicity
Assessment Factor Evaluation
	 c
v K a
S % "-













X
Meets
Relevance

X



X
X

X


X

X
8.1
|1
Si re
•5 a.
°- Ml
This source is considered relevant for
the CCL Universe because it contains
data elements derived from
toxicological studies.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements (LDx, NO(A)EL) from
toxicological studies.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source is considered relevant for
the CCL Universe because it has
elements that may indicate possible
occurrence and/or possible health
effects.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
Most data are available for regulated
contaminants. Some data are
available for unregulated
contaminants.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals that is related to
their toxicity/health effects.
Meets
Redundancy



X

X
X
X
X


X

X
>> c
s-l
•81
ll
"8 §-
OL w

The relevant data in this source are
redundant with ITER and IRIS.

This source is not redundant.

This source is not redundant.
This source is not redundant.
This source is not redundant.
This source is not redundant.


This source is partially redundant,
as it is mostly available as part of
NCOD - Six Year (source 136).

This source is not redundant.
Meets
Completeness

X



X
X
X
X


X

X
Documentation
of
Peer Review

Y

Unknown

Unknown
Y
N
Y


N

Y
il|

Y

N

Y
Y
Y
Y


Y

Y
Meets
Retrievability

X











X
& £
1= 0
!5 '*=
1 g
5! ra
!5 a.
IS x

This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with
automated retrieval.
This source does not meet retrievability
criteria. The source does not contain
data; it is a model that might be used to
generate estimates.


Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.

This source meets retrievability criteria
because it is in tabular format.
                                                                    A1-28

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID
192

193

194
195
196

197



198



199

Data Source Name
State of New Jersey Hazardous
Substances Right to Know Fact
Sheets

STN - CA/CA Plus File - Chemical
Abstracts

STN - CHEMLIST/HCHEMLIST -
Regulated Chemical Listing
STN - DETHERM
STN - Handbook Of Data on
Organic Compounds Database
(HODOC)

STN - Merck Index Online
(MRCK)



STN - NUMERIGUIDE



STN - Toxicology Center
(TOXCENTER)

Assessment Factor Evaluation
Meets All
Assessment
Factors


















Meets
Relevance
X



X













8.1
11
Si ra
•Ji Q.
rv x
01 LU
This source is considered relevant for
the CCL Universe because it contains
information on carcinogenicity and
potential health effects.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
a list related to health effects or
occurrence.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
Meets
Redundancy
X

X

X
X
X

X



X



X

>> c
s-l
Is
If
•§ §-
o: LU
This source is not redundant.

This source is not redundant.

This source is not redundant.
This source is not redundant.
This source is not redundant.

This source is not redundant.



This source is not redundant.



This source is not redundant.

Meets
Completeness
X

X

X
X
X

X







X

Documentation
of
Peer Review
Y

Unknown

Unknown
Unknown
Unknown

Unknown



Unknown



Unknown

Meets All
NDWAC
Requirements
Y

Y

Y
Y
Y

Y



N



Y

Meets
Retrievability


















& c
1= 0
!5 '*=
1 g
5! _re
IS x
OL "J
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.

This source does not meet retrievability
criteria because it is only available
through a subscription.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

                                                                    A1-29

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID
200

201


202


271


203


181


251

254

Data Source Name
STN-ZREGISTRY

STN and STN Easy - Scientific
and Technical Information
Network


STORE! - STORage and
RETrieval


Structure and Nomenclature
Search System


Substance Registry System (SRS)


Superfund Contract Laboratory
Program (SCLP) Water/Soil Data


Syracuse Research Corporation
(SRC) - BIODEG

Syracuse Research Corporation
(SRC) - BIOLOG

Assessment Factor Evaluation
Meets All
Assessment
Factors











X





X



Meets
Relevance





X





X


X


X



8.1
|1
Si ra
•Ji Q.
rv x
01 LU
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source does not meet relevance
criteria because it contains a chemical
list that is not related to health effects
or occurrence.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals that is related to
potential exposure.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
information on persistence, that may
be used as an indicator of potential
occurrence.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
Meets
Redundancy
X

X


X


X


X


X


X

X

>> c
s-l
Is
If
•§ §-
o: LU
This source is not redundant.

This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is not redundant.

This source is not redundant.

Meets
Completeness
X




X





X


X


X

X

Documentation
of
Peer Review
Unknown

Unknown


N


Unknown


N


Y


Y

Y

Meets All
NDWAC
Requirements
Y

N


Y


N


Y


Y


Y

Y

Meets
Retrievability











X





X



& c
1= 0
!5 '*=
1 g
5! _re
IS x
OL "J
This source does not meet retrievability
criteria because it is only available
through a subscription.

This source does not meet retrievability
criteria because it is only available
through a subscription.

Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
SRS is retrievable by EPA. SRS is
EPA's registry and provides the
identifying EPA data standards for the
CCL substances.
Data are retrievable by EPA but require
special processing and analysis for CCL
use. Designated as a supplemental
source.

This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

                                                                    A1-30

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID

252

184


253


185
186

187


282

207
Data Source Name

Syracuse Research Corporation
(SRC) - CHEMFATE

Syracuse Research Corporation
(SRC) - Chemical Pointer File


Syracuse Research Corporation
(SRC) - DATALOG


Syracuse Research Corporation
(SRC) - Environmental Fate
Databases (EFDB)
Syracuse Research Corporation
(SRC) - Physical Property
Database (PHYSPROP)
Syracuse Research Corporation
(SRC) - Simplified Molecular Input
Entry System (SMILECAS
Database)

Terrestrial Toxicity Information

The Institute for Genomics
Research (TIGR) Microbial
Database
Assessment Factor Evaluation
Meets All
Assessment
Factors


















Meets
Relevance









X








8.1
11
Si ra
•Ji Q.
rv x
01 LU
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it contains a chemical
list that is not related to health effects
or occurrence.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
information on persistence, that may
be used as an indicator of potential
occurrence.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
Meets
Redundancy

X

X


X



X






X
>> c
s-l
Is
If
•§ §-
o: LU

This source is not redundant.

This source is not redundant.


This source is not redundant.


This source is redundant. It is
available as a suite of data sources:
BIOLOG, BIODEG, CHEMFATE,
and DATALOG.
This source is not redundant.

This source is redundant with NCI-
3D (source 135).


This source is redundant with
ECOTOX (source 57).

This source is not redundant.
Meets
Completeness

X

X


X


X
X

X




X
Documentation
of
Peer Review

Y

Unknown


Y


Unknown
Unknown

Unknown


Unknown

Y
Meets All
NDWAC
Requirements

Y

Y


Y


Y
Y

Y


N

Y
Meets
Retrievability

X




X



X

X




X
& c
1= 0
!5 '*=
1 g
5! _re
IS x
OL "J

This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because it is only available
through a subscription.


This source meets retrievability criteria
because it is in tabular format.


This source does not meet retrievability
criteria because it is only available
through a subscription.
This source meets retrievability criteria
because it is in tabular format.

This source meets retrievability criteria
because it is in tabular format.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source meets retrievability criteria
because it is in tabular format.
                                                                    A1-31

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification

ID


205

138


153

154

240


206


212


208

250

Data Source Name


The Manual of Clinical
Microbiology, 7th edition.

The National Environmental
Methods Index (NEMI)


The Office of Ground Water and
Drinking Water (OGWDW) -
Consumer Fact Sheets

The Office of Ground Water and
Drinking Water (OGWDW) -
Technical Fact Sheets

The Open Practical Knowledge
Acquisition Toolkit (TOPKAT)

The Prokaryotes: A handbook on
the biology of bacteria:
Ecophysiology, Isolation,
Identification, and Applications

The Toxics Release Inventory
(TRI)


TOMES PLUS, MICROMEDEX -
Thomson-Micromedex

Total Exposure Assessment
Methodology Study (TEAM)
Assessment Factor Evaluation
5 | £
« tn 2
15 °> o
v % ™
E 8"-
<
















X





HI
o
•& £
* 5
s 3>
&










X





X


X

X
8.1
> c
"Ji Q.
rv x
01 w
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are

inconsistently presented.
This source does not meet relevance
criteria because it contains only
information for regulated
contaminants.
This source does not meet relevance
criteria because it contains only
information for regulated
contaminants.
This source is considered relevant for
the CCL Universe because it could be
a source of information on potential

This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it contains
information on chemical releases,
which may indicate potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
information on potential health effects.
>.
o
a |
Si £
El

X

X


X

X

X


X


X


X

X
>> c
s-l
2 re
1 <=
3 —
Q: UJ

This source is not redundant.

This source is not redundant.


This source is not redundant.

This source is not redundant.

This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is not redundant.

This source is not redundant.
to
8
16 v
813
Sf
o
O

X

X


X

X

X


X


X


X

X
° 9
« 1
| o n:
3 0)
° *

Y

Y


Y

Y

Unknown


Y


Y


Y

Unknown
3g|
Is *
$ 9 3
" J

Y

Y


Y

Y

Y


Y


Y


Y

Y
&
£ 1
a! Z
0> a<
E-g
1
















X





& £
1= 0
% re
§ 1
1 g-
OL "J
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria. This source has data in a
tabular format, but it is not formatted to
allow complete data extraction with


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria. The source does not contain
data; it is a model that might be used to
generate estimates. The source is only
available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.

This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval, and it
is only available through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
                                                                    A1-32

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID

288
209


211


284
213
214
216
217
Data Source Name

Toxic Substances Control Act
(TSCA) List
Toxicity Criteria Database -
California Office of Environmental
Health Hazard Assessment
(OEHHA)

TOXLINE


TSCA Plant and Production
TSCATS - Toxic Substances
Control Act Test Submissions
UCM - Round 2 (SDWIS/FED) -
Unregulated Contaminant
Monitoring
University of Akron Chemical
Database
University of Maryland - Partial
List of Acute Toxins/Partial List of
Teratogens
Assessment Factor Evaluation
a! K re
S % "-

X
X









X
Meets
Relevance

X
X





X
X
X

X
8.1
|1
Si re
•5 a.
°- Ml
This source is considered relevant for
the CCL Universe because it is a list
and contains information on production
volume, which may indicate potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements derived from
toxicological studies.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it is a list
and contains information on production
volume, which may indicate potential
occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source does not meet relevance
criteria because it contains only
chemical property information that is
not relevant to the CCL Universe.
This source is considered relevant for
the CCL Universe because it contains
a list of chemicals with known
toxicity/health effects.
Meets
Redundancy

X
X


X


X
X

X
X
>> c
s-l
•81
if
0) X
£ UJ

This source is not redundant.
This source is not redundant.


This source is not redundant.


This source is not redundant.
This source is not redundant.
This source is redundant, as it is
wholly available as part of NCOD -
Round 1&2 (source 137).
This source is not redundant.
This source is not redundant.
Meets
Completeness

X
X


X



X
X

X
Documentation
of
Peer Review

Unknown
Y


Y


Unknown
Y
Y
Unknown
Unknown
il|

Y
Y


Y


N
Y
Y
N
Y
Meets
Retrievability

X
X







X

X
& c
1= 0
!5 '*=
1 g
5! ra
5 °-
d) X

This source meets retrievability criteria
because it is accessible through EPA's
Substance Registry System.
This source meets retrievability criteria
because it is in tabular format.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
This source meets retrievability criteria
because it is in tabular format.
                                                                    A1-33

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID

215


219

220


273



221


222


223

Data Source Name

University of Minnesota
Biocatalysis & Biodegradation
Database (UM-BBD)


Unregulated Contaminant
Information System (URCIS)

US Army Center for Health
Promotion and Medicine Detailed
Chemical Fact Sheets


US EPA Civil Enforcement Docket



Victorian Infectious Diseases
Reference Laboratory (VIDRL)


Voluntary Cosmetic Registration
Program Database (VCRP)


Wastelnfo - AEA Technology

Assessment Factor Evaluation
Meets All
Assessment
Factors





















Meets
Relevance




X

X














8.1
11
Si ra
•Ji Q.
rv x
01 LU
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source is considered relevant for
the CCL Universe because it contains
measurements of contaminants in
water, demonstrating occurrence.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source does not meet relevance
criteria because it consists of text
abstracts on subjects not pertaining to
CCL CP, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
Meets
Redundancy

X




X


X



X


X


X

>> c
s-l
Is
If
•§ §-
o: LU

This source is not redundant.

This source is redundant, as it was
converted into NCOD Round 1
database, so URCIS is no longer
needed.
This source is not redundant.


This source is not redundant.



This source is not redundant.


This source is not redundant.


This source is not redundant.

Meets
Completeness

X


X

X


X











Documentation
of
Peer Review

Unknown


Y

Y


Unknown



Unknown


Unknown


N

Meets All
NDWAC
Requirements

Y


Y

Y


Y



N


N


N

Meets
Retrievability




X
















& c
1= 0
!5 '*=
1 g
5! _re
IS x
OL "J

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because it is only available
through a subscription.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

                                                                    A1-34

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification
ID
228
229

224


225


236


226

227
Data Source Name
Water Environment Research
Foundation (WERF) Microsheets
Water Environment Research
Foundation (WERF) Toxicity
Datasheets

Water Resources Abstracts -
Cambridge Scientific Abstracts


Water Resources Worldwide


WATERLIT


WATERNET - American Water
Works Association

Weekly Epidemiological Record
(WER)
Assessment Factor Evaluation
a! K re
S % "-















Meets
Relevance

X













8.1
|1
d) re
•Ji Q.
n- x
V- UJ
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
This source is considered relevant for
the CCL Universe because it could be
a source of information on health
effects.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
This source does not meet relevance
criteria for the chemical universe
because it contains only information on
microbial contaminants.
Meets
Redundancy
X
X

X


X


X


X

X
>> c
s-l
•81
ll
"8 §-
OL UJ
This source is not redundant.
This source is not redundant.

This source is not redundant.


This source is not redundant.


This source is not redundant.


This source is not redundant.

This source is not redundant.
Meets
Completeness
X
X

X








X

X
Documentation
of
Peer Review
Y
Y

N


N


Unknown


N

Y
il|
Y
Y

Y


N


N


Y

Y
Meets
Retrievability















& £
1= 0
!5 '*=
1 g
5! ra
!5 a.
IS x
This source does not meet retrievability
criteria because it is only available
through a subscription.
This source does not meet retrievability
criteria because it is only available
through a subscription.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.
                                                                    A1-35

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                         Appendix 1. CCL 3 All Data Sources - Assessment Table
Source Identification

ID


85

86

40


230


Data Source Name


WHO Guidelines for Drinking
Water Quality: Chemical Aspects:
Index of Chemicals

WHO Guidelines for Drinking
Water Quality: Summary Tables

WHO Recommended
Classification of Pesticides by
Hazard (CPH)

World Health Organization -
Information Products Catalogue

Assessment Factor Evaluation
	 c

s % "-
"*


X






HI
u
+2 c
Is
$

X

X

X




8.1
|1
d) re
m o.
OL x
"• LU
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements from toxicological
studies.
This source is considered relevant for
the CCL Universe because it contains
data elements derived from
toxicological studies.
This source does not meet relevance
criteria because it consists of text
(titles and/or abstracts) on many
subjects that may not pertain directly
to CCL, and its data elements are
inconsistently presented.
u
c
j2 re
tu -o
HI c
g 3

OL
X

X

X


X

>> c
go
si
il
•§ §-
£ UJ
This source is not redundant.

This source is not redundant.

This source is not redundant.


This source is not redundant.

to
to
HI
a |
^ "5.
E
O
X

X

X


X

° 9
"S *
! o £

Q °"
Y

Y

Y


Y

1
III
S z f
K
Y

Y

Y


Y

t
a! Z
1 §
a!



X






&• c
1= 0
1 g
5! _re


This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

This source meets retrievability criteria
because it is in tabular format.

This source does not meet retrievability
criteria because, with the exception of
the classifications, it is not formatted for
automated retrieval.

This source does not meet retrievability
criteria because the data are not
formatted for automated retrieval.

                                                                    A1-36

-------
EPA-OGWDW
                                                                                                      Final CCL 3 Chemicals: Identifying the Universe
                                                                                                 Appendix 2. CCL 3 Universe of Data Sources
                                                                                                                                                                                                                                  EPA815-R-09-006
                                                                                                                                                                                                                                       August 2009
Source Identif
ID Data Source Name
12 ATSDR CERCLA Priority List
123 ATSDR Minimal Risk Levels (MRLs)
Chemical Toxicity Database -
31 Ministry of Health and Welfare,
Japan
Chemical Update System/Inventory
Update Rule (CUS/IUR)
Cumulative Estimated Daily
26 Intake/Acceptable Daily Intake
(CEDI /ADI) Database
Database of Sources of
46 Environmental Releases of Dioxm-
Like Compounds in the United States
Distributed Structure Searchable
53 Toxicity Public Database Network
(DSSTox)
,-, Everything Added to Food in the
United States (EAFUS) Database
9-g Federal Insecticide, Fungicide, and
Rodenticide Act (FIFRA) List
„, Generally Regarded As Safe (GRAS)
Substance List
Guidelines for Canadian Drinking
83 Water Quality (CADW) Summary of
Guidelines
Hazardous Substances Data Bank
95 (HSDB)
0_ Heallh Advisories (HA) Summary
31 Tables -EPA

Chemical List


Information Collection Rule(ICR)
Federal Database
1flfi Integrated Risk Information System
(IRIS)
„„ International Agency for Research on
Cancer (IARC) Monographs
cation
Proprietor
Agency for Toxic Substances and
Disease Registry
Agency for Toxic Substances and
Disease Registry
Ministry of Health and Welfare,
Japan
EPA
FDA- Center for Food Safety and
Applied Nutrition
EPA, ORD
EPA
FDA - Center for Food Safety and
Applied Nutrition, CFSAN, Office
of Food Additive Safety
EPA
FDA - Center for Food Safety and
Applied Nutrition
Health Canada
National Library of Medicine, NIH
EPA Office of Water, OST

Drevention and Toxics (OPPT)
FDA- Center for Food Safety and
of Food Additive Safety
EPA Office of Ground Water and
Drinking Water
EPA Office of Research and
Development, ORD, National
Center for Environmental
nternational Agency for Research

II
i 3
|o
N
N
N
N
N
N
N
N

N
N
N
N

H


v
N
N

|l
fl
Y
N
N
v
N
v
N
N

N
N
v
N




N
N
N

||
N
Y
Y
N
Y
N
v
N

N
Y
Y
v

H


N
Y
v

Potential
Health Effects?
v
N
N
N
N
N
v
Y

Y
N
N
N

H


N
N
N
Relevance

This source is considered relevant for the CCL
Universe because the basis for developing this list
is ATSDR's pnontization of chemicals found at
NPL sites and that ATSDR believes may pose a
This source is considered relevant for the CCL
Universe because it contains data elements
(MRL) derived from lexicological studies
This source is considered relevant for the CCL
Universe because it contains data elements
(LD50, NOEL) from lexicological studies
This source is considered relevanl for Ihe CCL
produclion volume, which may indicate potential
This source is considered relevanl for Ihe CCL
Universe because il contains health effects dala
This source is considered relevanl for Ihe CCL
This source is considered relevanl for Ihe CCL
Universe because il conlams dala elemenls from
lexicological sludies
Universe because il conlams a list of chemicals
thai is related lo potential exposure
This source is considered relevant for Ihe CCL
thai is related lo potential exposure
This source is considered relevant for Ihe CCL
Universe because it conlams a list of chemicals
thai is related lo their toxi city/health effects
This source is considered relevant for the CCL
Universe because il conlams dala elemenls (ADI ,
NO(A)EL) from lexicological sludies
This source is considered relevanl for Ihe CCL
Universe because il conlams dala elemenls from
lexicological sludies
This source is considered relevanl for Ihe CCL
This source is considered relevanl for Ihe CCL
infamal on^o^prod^uclim volm-ne^ which may
This source is considered relevanl for Ihe CCL
that is related to potential exposure
This source is considered relevant for the CCL
This source is considered relevanl for Ihe CCL
Universe because il conlams dala elemenls from
lexicological sludies
This source is considered relevanl for Ihe CCL
lexicological sludies
Redundancy

This source is nolredundanl
These dala are also represenled in
Ihe ATSDR Toxicological Profiles,
however, Ihese dala arelabular
whilelhe Profiles are monographic
This source is nolredundanl
This source is nolredundanl
This source is nolredundanl
This source is nolredundanl
This source is nolredundanl
This source is nolredundanl
This source is nolredundanl
This source is nolredundanl
This source is nolredundanl
This source is nolredundanl
Th,5 ™SM „*„*„,

This source is nol redundanl


—
source are available in labular
formal from ITER (#110) and RAIS
HeallhEffecls(#178) Hence there
is some overlap and redundancy,
bul each also provide addilional
elsewhere
—
Com pi
i i
SI
5*
E o>
8£
Y
Y
Y
Unknown
v
v
Unknown
v
Unknown
v
v
v
v




v
Y
v
teness
Meets All NDWAC
Requirements
Y
Y
Y
Y
v
Y
v
Y
Y
Y
v
Y
v




v
v
v

•H
1
1
Tabular
Tabular
Tabular/Monogr
aphic
Tabular
Tabular
Tabular
Tabular
Tabular
Unknown
Monographic
(can be
labular form all
Tabular
Monographic
Tabular




Tabular
Monographic
Monographic
Retr
1
N
N
N
N
N
N
N
N
unk™
N
N
N
N

H


v
N
N
evability

This source meels rein evabi lily
cnlena because il is in labular
This source meels rein evabi lily
cnlena because il is in labular
This source meels rein evabi lily
criteria because Ihe relevanl
dala can be extracted in
This source meets rein evabi lily
criteria because His in labular
This source meels rein evabi lily
criteria because His in labular
This source meels rein evabi lily
criteria because His in labular
formal
This source meels rein evabi lily
dala can be extracted in
tabular formal
This source meels rein evabi lily
criteria because His in labular
formal
This source meels rein evabi lily
criteria because il is accessible
Ihrough EPA's Subslance
Regislry System
This source meels rein evabi lily
labular formal
This source meels rein evabi lily
criteria because His in labular
HSDBisrelnevable The dala
are nol formatted for
aulomaled relneval The
HSDB is a unique and
exceplional source and is
included losupplemenl Ihe
CCL Universe
This source meels rein evabi lily
criteria because His in labular
This source meels rein evabi lily

This source meels rein evabihly
formal
Dala are retrievable by EPA
They may require special
retrieval However, the
lexicological dala from this
source have been compiled for
electronic retrieval in ITER,
and were obtained from there
IRIS monographs were used to
in this source is not relnevable,
however, Ihe list of
contammanls and their cancer
groups is retrievable and will
be used for the CCL Universe
IARC is a unique and
exceplional source and is
included losupplemenl Ihe
CCLU

1
v
N
N
N
N
N
N
Y

Y
N
N
N




N
N
N

.*>
N
N
N
N
N
N
v
N

N
N
Y
N

H


N
N
v

<^-
TB
3
b
s
N
N
N
N
N
N
N
N

N
v
N
v

H


v
N
N

I
N
N
N
N
N
N
N
N

N
N
N
N

H


N
N
N

No of Contaminants
313
i*
222
13753
1118
168
1557
3284

114
157
4688
216




10
650
890

££
£°
1
CERCLA
Chemicals
HPV Chemicals
TSCA
Chemcials
Food Contact
Dioxin-like
Compounds
Chemicals
Food Additives

Food Additives
Microbes
Chemicals
Chemicals,
Inorganics,


Food Contact
Substances
Pathogens,
DBFs
Chemicals
Carcinogens

Type of Data Elements
Name, CASRN, rank
Name, CASRN, MRL (chronic, intermediate,
Name, CASRN, formula, LD50, NOEL, mutation
data
Production Volume
Name, CASRN, ADI, CEDI, CUM DC
Emmissions, Release to Air
TD50
Name, CASRN, status of toxicology information
Unknown
Notifier, Intended Use, Basis, Receipt Date,
Closure Date
ADI, AO, CR, Critical Effect, DCF, Dose,
Duration, Environmental Fate, Guideline,
Half-lifet1/2 (days), IMAC (mg/L), LDx, MAC,
NO(A)EL, Occurrence, Physical/Chemical,
Production/Use, Route
Name, CASRN, synonyms, ID numbers, Use,
Production, IARC cancer class, EPA cancer
group, Evidence for carcinogen icity, Critical
effect, Mutagenicity, Irritation data, Susceptible
populations, BocV burden, Occupational
exposure, MTD, LDx, Estimated daily i
Name, CASRN, CR, DWA, DWEL, HA(1d, 10d,
lifetime), MCL, MCLG, RfD, SDWR



CFSAN Name, CASRN, Regulation Number
DBP Occurrence Concentrations
Name, Synonyms, CASRN, RfC, RfD, SF(i.o),
UR(i.o), NO(A)EL, LO(A)EL, BMC/D, BMDL,
Critical effect
Summary of Data Reported and Evaluation,
Exposure data, Human carcinogen icity data,
Animal carcinogen icity data, Other relevant data,

Potential Update
Frequency
B,™e,y
B,™e,y
As Needed
Every 4
As Needed
NA
As needed
As Needed

Variable
Annually
Quarterly
Biennially




Finished
As Needed
As Needed

Last Updated
(per last check)
2003
2003
2002
2002
2002
1995
2004
2004

2004
2003
2003
2004




1998
2003
2002

-------
EPA-OGWDW
                                                                                                      Final CCL 3 Chemicals: Identifying the Universe
                                                                                                 Appendix 2. CCL 3 Universe of Data Sources
                                                                                                                                                                                                                                  EPA815-R-09-006
                                                                                                                                                                                                                                       August 2009
Source Identif
ID Data Source Name
,,n International Toxicity Estimates for
Risk(ITER) Database
Joint Meeting On Pesticide Residues
112 (JMPR)- 2001 Inventory of Pesticide
Evaluations
National Drinking Water Contaminant
137 Occurrence Database (NCOD)-
Round 1&2
National Drinking Water Contaminant
233 Occurrence Database (NCOD)-
Rule(UCMR)
National Inor amcsand
144 Radionuclides Survey (NIRS)
128 National Pesticide Use Database
National Reconnaissance of
USGS Toxic Substances Hydrology
Program
National Toxicology Program (NTP)
248 Studies
134 National Water Quality Assessment
9,, OSHA 1988PermissibleExposure
Limits (PELs)
265 Pesticide Data Program
1Rd Pesticides Pilot Monitoring Program -
USGS/EPA
177 System (RAIS) - Department of
Energy- Chemical Factors
178 System (RAIS) - Department of
Energy - Health Effects Data
State of California EPA Chemicals
191 Known tothe State toCause Cancer
203 Substance Registry System (SRS)
Syracuse Research Corporation
(SRC)-BIODEG
212 TheToxics Release Inventory (TRI)
„„ Toxic Substances Control Act
(TSCA) List
cation
Proprietor
TERA - Toxicology Excellence for
Risk Assessment / NLM
World Health Organization, Food
EPA Office of Ground Water and
Drinking Water
EPA Office of Ground Water and
Drinking Water

Group, Inc
National Center for Food and
Agricultural Policy (NCFAP)

USGS
National Toxicology Program, NIH
USGS
NIOSH
USDA
EPA Office of Ground Water and
Drinking Water and USGS
NAWQA
U S Department of Energy
U S Department of Energy
State of California
EPA
Syracuse Research Corporation
EPA
EPA

11
I 3
Is
N
N
v
v


N

Y
N
v
N
N
v
N
N
N
N
N
N
N

|l
fl
N
N
N
N

H
v

N
N
N
N
v
N
v
N
N
N
v
Y
Y

||
Y
v
N
N

H
N

N
Y
N
v
N
N
N
v
N
N
N
N
N

Potential
Health Effects?
N
N
N
N

H
N

N
N
N
N
N
N
N
N
Y
N
N
N
N
Relevance

This source is considered relevant for the CCL
Universe because it contains data elements
directly from and derived from lexicological
studies
This soiree is considered relevant for the CCL
Universe because it contains data elements
derived from lexicological studies
This source is considered relevanl for Ihe CCL
unregulated conlammanls in drinking water,
demonstrating occurrence
This source is considered relevanl for Ihe CCL
conlammanls in drinking waler, demonslralmg
This source is considered relevanl for Ihe CCL
Universe because il contains measurements ol
This source is considered relevanl for Ihe CCL
peslicide use, an mdicalor of potential occurrence

Universe because it contains measuremenls of
This source is considered relevanl for Ihe CCL
Universe because il conlams dala elemenls from
lexicological sludies
This source is considered relevanl for Ihe CCL
This source is considered relevanl for Ihe CCL
Universe because il conlams inhalation exposure
This source is considered relevant for the CCL
peslicide residues, an indicator of potential
This source is considered relevant for Ihe CCL
Universe because it conlams measuremenls of
conlammanls in waler, demonslralmg occurrence
This source is considered relevanl for Ihe CCL
Universe because il conlams radioactive half-life
dala, providing an mdicalor of occurrence
This source is considered relevanl for Ihe CCL
Universe because il conlams dala elemenls
direcllyfrom and derived from lexicological
sludies
This source is considered relevanl for Ihe CCL
Universe because il conlams a list of chemicals
thai is related lolheirloxicily/heallh effects
This source is considered relevanl for Ihe CCL
Universe because il conlams a list of chemicals
that is related lo potential exposure
This source is considered relevant for Ihe CCL
persistence, that may be used as an indicator of
potential occurrence
This source is considered relevant for Ihe CCL
chemical releases, which may indicate potential
This source is considered relevant for Ihe CCL
indicate potential occurrence
Redundancy

This source is not redundanl
Th,5 „„„„„, „*„*„,
—
This source is not redundanl

This source is nol redundanl
—

This source is nol redundanl
This source is nol redundanl
This source is nol redundanl
This source is nol redundanl
This source is nol redundanl
This source is nol redundanl
This source is nol redundanl
This source is nol redundanl
This source is nol redundanl
This source is nol redundanl
This source is nol redundanl
This source is nol redundanl
This source is nol redundanl
Com pi
s 8
SI
S"
E u
3£
v
v
v
N


Unknown

Y
v
v
v
-"-"
Y
v
Y
v
N
v
Y
Unknown
"teness
Meets All NDWAC
Requirements
Y
v
v
v


v

Y
Y
v
v
v
v
Y
v
Y
Y
Y
v
v

•H
1
1
Tabular
Tabular
Tabular
Tabular


Tabular

Monographic
Monographic
Tabular/
Monographic
Monographic
Tabular
Tabular/
Monographic
Tabular/Monogr
aphic
Tabular/Monogr
aphic
Tabular
Tabular
Tabular
Tabular
Unknown
Retr
1
N
N
N
N

H
N

N
Y
N
N
N
N
N
N
N
N
N
N
-r
evability

This source meels rein evabi lily
criteria because it is in tabular
format
This source meels relnevabihly
criteria because it is in tabular
format
This source meels rein evabi lily
criteria because His in labular
formal
This source meels relnevabihly
criteria because His in labular
formal
This source meels relnevabihly
formal
This source meels rein evabi lily
This source meels rein evabi lily
provided Ihe dala direclly lo
EPA in auseableformal
This source does net meel
rein evabi lily criteria because
Ihe dala are nol formatted for
automated relneval NTP
sludies provide unique and
exceplional dala and are
included to supplement the
CCL Universe
criteria because USGS
provided the dala direclly lo
EPA in auseableformal
This source meels relnevabihly
criteria because His in labular
This source meels relnevabihly
criteria because His in labular
formal
This source meels rein evabi lily
criteria because Ihe relevanl
dala can be extracted in
tabular formal
This source meels rein evabi lily
labular formal
This source meels rein evabi lily
dala can be extracted m
===,?
SRSisrelnevablebyEPA
SRS is EPA's regislry and
provides Ihe identifying EPA
data slandards for Ihe CCL
criteria because il is in labular
™==r,?
This source meels rein evabi lily
criteria because il is accessible
Ihrough EPA's Subslance
Regislry System

?
N
N
N
N

H
N

N
N
N
N
N
N
N
N
Y
N
N
N
v

I
N
N
N
N

H
N

N
N
N
N
N
N
Y
N
N
Y
Y
N
N

<^-
TB
3
b
s
N
N
v
N

H
N

N
N
N
N
N
N
N
N
N
v
N
N
N

I
N
N
N
N

H
N

N
N
N
N
N
N
N
N
N
N
N
N
N

No of Contaminants
533
240
76
23

42
235

123
715
224
«
219
177
1498
1479
694
83000
762
509


££
£°
1
Chemicals
Peslicides
Unregulated
Chemicals,
Microbes
Unregulated
Chemicals

Radionuclides
Pesticides

Use Chemicals
Chemicals
Nutnenls,
Peslicides,
VOCs
Occupalional
Chemicals
Peslicides
Peslicides
Chemicals
Chemicals
Carcinogens
Chemicals,
Microbes
Chemicals
Chemicals
Induslnal
Chemicals

Type of Data Elements
Name, CASRN, Critical effect, Cancer risk, Slope
factor, MRL, RfD, RfC, TC(A), TDI , RSC, RSD,
LOJAJEL, NOJAJEL, TumCx, TumDx, TC05,
TC01.TD05, TI.TC, Risk Value, Basis
Name, CASRN, ADI
Drinking waler occurrence concenlralions
--=--»—


Name, Ibs Al applied, # Slates applied

Max Value
Categories of evidence of carcinogenic activity,
Occurrence Con central ions
Name, CAS RN, OSHA PEL
Total Samples Analyzed, Samples with Residues
Detected, Percent of Samples with Deteclions,
Different Pesticides Detecled, Different Residues
Detecled, Tolal Residue Deleclions, % of
Samples with Detecls, Minimum Value
Delected, ppm, Maximum ValueDelecled
Dn*ngwa,er0=™nceconcen™s
Name, CASRN, Absorplionfaclor, beef Iransfer
coefficient, BP, Soil to Plant dry uplake, Soil lo
Planl wel uplake, Diffusely in air, Diffusivily in
water, Fish bioaccumulalion factor, Gl absorplion
faclor, Gl absorplion fraction, Radioactive half
life,
RfD (critical effect), RfC, Slope Factor, Unit Risk,
Absorplion Fad or, Cancer Class
Name, CASRN, Dale added lo list,
Carcinogen i city and Reproductive Toxicily
CASRN, Classification, Molecular Formula,
Molecular Weight, Regulatory Resources, Olher
Sources, Group/ Componenl, Related Links
Name, CASRN, Biodegradalion - aerobic,
anaerobic, soil, sediment, sewage, fresh water,
seawater, olher
Chemical releases lo air, land, and waler
Unknown

Potential Update
Frequency
As Needed
As Needed
As Needed
As Needed

None
Every 5
years

Annually
unta
As Needed
unl™
unl™
Finished
As Needed
As Needed
Annually
unta
Quarterly
Annually


Last Updated
(per last check)
2003
2002
2002
2004


1997

2000
2003
2002
u*™n
U*™n
2000
2003
2003
2004
2002
2004
2002


-------
EPA-OGWDW
                                                                                                      Final CCL 3 Chemicals: Identifying the Universe
                                                                                                 Appendix 2. CCL 3 Universe of Data Sources
                                                                                                                                                                                                                                  EPA815-R-09-006
                                                                                                                                                                                                                                       August 2009
Source Identif
ID Data Source Name
Toxicity Criteria Database - California
Hazard Assessment (OEHHA)
University of Maryland - Partial List of
Teratogens
WHO Guidelines for Drinking Water
Quality Summary Tables
cation
Proprietor
California Office of Environmental
Health Hazard Assessment

University of Maryland
World Health Organization

11
I 3
Is



1
N

|l
fl



"
N

||



1
v

Potential
Health Effects?



'
N
Relevance

This soiree is considered relevant for the CCL
derived from lexicological studies
This source is considered relevant for the CCL
with known toxi city/ health effects
This source is considered relevant for the CCL
Universe because it contains data elements from
Redundancy




This source is not redundant
This source is not redundant
Com pi
s i
SI
5*
E o>
8£



Unknown
Y
"teness
Meets All NDWAC
Requirements



Y
v

ts
1
1



Tabular
Tabular
Retr
1



N
N
evability

This source meets retn evability
term at
This source meets retn evability
format
This source meets retn evability
criteria because it is in tabular

1



'
N

.*>



"
N

<^-
TB
3
b
s



"
N

I



"
N

No of Contaminants



2519
137

££
£°
1



Chemicals
Chemicals

Type of Data Elements
Critical effect, CAMCL, CAPHG, cancer risk,
unit risk

Name
Name, GV.TDI, basis

Potential Update
Frequency



Not Updated
As Needed

Last Updated
(per last check)



1995
1998

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                                  Appendix 3. CCL 3 Universe Supplemental Data Sources
Source Identification
ID
1
9
13
210
235
24
28
38
35
41
241
50
242
Data Source Name
10th Report on Carcinogens- NTP
Alternate Crops and Systems (ARS)
Pesticide Properties Database
ATSDR Internet HazDat - Site
Contaminant Query
ATSDR Toxicological Profiles
California Department of Pesticide
Regulation (CDPR)
Chemical Carcinogenesis Research
Information System (CCRIS)
Chemical Evaluation Search and
Retrieval (CESARS) - CCOHS
Comprehensive Environmental
Response, Compensation, and
Liability Information System
(CERCLIS)
Concise International Chemical
Assessment Documents (CICADs)
CrossFire BEILSTEIN
Derek
Dictionary of Substances and Their
Effects - Knovel
EC Water Directive
Proprietor
Department of Health and
Human Services - National
Toxicology Program
Alternate Crops & Systems
Laboratory, United States
Department of Agriculture
Agency for Toxic Substances
and Disease Registry
Agency for Toxic Sutstances and
Disease Registry; an agency of
the U.S. Department of Health
and Human Services (DHHS),
Centers for Disease Control
(CDC)
California Department of
Pesticide Regulation
National Library of Medicine;
NIH; developed and maintained
by NCI
Canadian Center for
Occupational Health and Safety
(CCOHS)
EPA Envirofacts Data
Warehouse and Applications
International Programme for
Chemical Safety, World Health
Organization, International
Labour Organisation, United
Nations Environment Programme
MDL Information Systems GmbH
(formerly known as BEILSTEIN
Informations systemme)
LHASA Limited
Knovel
European Community
Assessment Factor Evaluation
Relevance
Demonstrated
Occurrence?
N
N
Y
N
N
N
N
N
N
N
N
N
N
Potential
Occurrence?
N
Y
N
N
N
N
N
Y
N
Y
N
N
N
^ L1J
0 -C
l|
Y
N
N
Y
N
Y
Y
N
Y
N
N
Y
N
j|
0)
X
Y
N
N
N
N
N
N
N
N
Y
Y
N
N

This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains information on
persistence, that may be used as an indicator of
potential occurrence.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in water, demonstrating
occurrence.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies and information on
production, which may indicate potential
occurrence.
This source is considered relevant for the CCL
Universe because it contains a list of bioactive
compounds.
This source is considered relevant for the CCL
Universe because it contains the results of
carcinogen! city and mutagenicity studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains information on
potential contaminant occurrence at superfund
sites.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies and environmental fate data,
providing an indicator of potential occurrence.
This source is considered relevant for the CCL
Universe because it could be a source of
information on potential health effects.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains regulatory limits for
contaminants in drinking water.
Redundancy

This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
Completeness
Documentation of
Peer Review
Y
Y
Unknown
Y
Y
Y
Y
Y
Y
Y
Unknown
Y
Unknown
Meets All NDWAC
Requirements
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Y
Retrievability
Data Format
Monographic
Tabular
Tabular
Monographic
Text
Monographic
Monographic
Tabular
Monographic
Monographic
Model
Unknown
Legislation
Subscription
N
N
N
N
N
N
Y
N
N
Y
Y
Y
No

This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria. This
source has data in a tabular format, but it is not
formatted to allow complete data extraction with
automated retrieval.
This source does not meet retrievability criteria. This
source has data in a tabular format, but it is not
formatted to allow complete data extraction with
automated retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria. This
source has data in a tabular format, but it is not
formatted to allow complete data extraction with
automated retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval, and it is only available through a
subscription.
Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval, and it is only available through a
subscription.
This source does not meet retrievability criteria. The
source does not contain data; it is a model that might
be used to generate estimates. The source is only
available through a subscription.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval, and it is only available through a
subscription.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                                  Appendix 3. CCL 3 Universe Supplemental Data Sources
Source Identifi


ID


1
9
13

210

235
24
28
38
35

41

941

50
242


Data Source Name


10th Report on Carcinogens - NTP
Alternate Crops and Systems (ARS)
Pesticide Properties Database
ATSDR Internet HazDat - Site
Contaminant Query

ATSDR Toxicological Profiles

California Department of Pesticide
Regulation (CDPR)
Chemical Carcinogenesis Research
Information System (CCRIS)
Chemical Evaluation Search and
Retrieval (CESARS) - CCOHS
Comprehensive Environmental
Response, Compensation, and
Liability Information System
(CERCLIS)
Concise International Chemical
Assessment Documents (CICADs)

CrossFire BEILSTEIN

Derek

Dictionary of Substances and Their
Effects - Knovel
EC Water Directive


Lj


Y
N
N

N

Y
N
N
N
N

N

N

N
N
$
t
0)
a.
o
a.

U
N
Y
N

Y

N
N
Y
N
N

Y

N

N
N

CO
I


N
N
N

N

N
N
N
N
N

N

N

N
Y

o
a.
ai
_o
.Q
m

N
N
N

N

N
N
N
N
N

N

N

N
N

2
'E
<3
O
O

228
334
5198

269

887
>8000
850
1700
55

8 million+

NA

4600
Unknown

c
1
32
8.

Chemicals,
Inorganics
Pesticides
Chemicals



Pesticides
Carcinogens
Chemicals
CERCLA
Contaminants
Chemicals

Chemicals

Chemicals

Chemicals
Chemicals,
Microbes


Type of Data Elements


Name, CASRN, IARC cancer class, vapor pressure, vapor density, MP, BP, flash point, use,
production, critical effect, exposure potential, releases, occupational exposure limits (PEL)
CASRN, formula, MW, Physical state, BP, MP, Decomposition point, Heat of vaporization, Rate
Constants- Hydrolysis, Photolysis, VP, Water solubility, Organic solubility, HLC, Kow, Acid
dissociation, Soil sorption, Field dissipation, Soil halflife (aerobic,
Maximum concentration, number of states
Name, CASRN, synonyms, trade names, structure, ID numbers, MW, color, physical state, MP,
BP, density, odor, solubility, log Kow, log Koc, VP, HLC, pKa, hydrolysis rate constant, autoignition
temp, flashpoint, flammability limits, explosive limits, critic
Name, number of products used in
Major Use, Administrative Information, Mutagenicity Study, Carcinogenicity Study,
Tumor Promotion, Tumor Inhibition
Properties- Physical and Chemical: Molecular formula, molecular weight, physical state, melting
point, boiling point, flash point, autoignition point, explosive limits, density, specific gravity, Henry's
law constant, pKa, TOD, BOD, COD, conversion facto
Facility Information, Site Name, Address, County, Site SMSA, Federal Facility, NPL Status,
Corporate, Mapping Info, Record of Decision (ROD) Info, EPA Regional, Latitude, Longitude,
Ownership, Site, Incident, Action, Responsibility, Planned Outcome, Urgen
Name, Formula, synonyms, CASRN, ID numbers, MW, density, BP, MP, water solubility, other
solubility, partition coefficients, Log Koc, Log Kow, VP, HLC, production, environmental fate,
BMC/D, ENEV, IARC cancer class, TC(A), CTV, ECx, ICx, LCx, LDx, LO(A)EL
Chemical Name, Effect, Species or Test-System, Route of Application, Kind of Dosing, Method,
Further Details, Results, Half-Life Time; Laboratory Use and Handling; Ecological Data;
Concentration in the Environment; Transport and Distribution; Bioconcentra
Name, Description, References, Endpoint, Comments, LHASA Predictions: Genotoxicity,
Mutagenicity, Skin sensitisation
Toxicity, Physical Properties, Regulatory Requirements, References
Parameter, Parametric value, Unit, Notes, Trueness % of parametric value, Precision % of
parametric value, Limit of detection % of parametric value, Conditions
0)
*5
11
•£ LJ.
S.

Biennially
As Needed
Regularly

As Needed

Daily
As Needed
Finished
Monthly
Semi-
annually

As Needed

NA

As Needed
Unknown

~° "o
1 1
Q. +*
"I

2001
2001
2004

2003

2004
2003
2002
2002
2002

2002

NA

2004
1998

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                                  Appendix 3. CCL 3 Universe Supplemental Data Sources




ID


59


64

76

78


84


88


89


91

94

92
109

111
113


Data Source Name


Endocrine Disrupter Priority Setting
Database (EDPSD)


Environmental Monitoring and
Assessment Program (EMAP)

Genetic Activity Profiles (GAP)
Database

GENE-TOX

Guidelines for Canadian Drinking
Water Quality (CADW): Supporting
Documentation

Health Advisory Documents


Health and Safety Guides - World
Health Organization, ILO, UNEP,
CCOHS

Health Effects Assessment
Summary Tables (HEAST) - EPA
NCEA
High Production Volume (HPV)
Challenge Program Robust
Summaries and Test Plans

Human Exposure Database System
(HEDS)
International Register of Potentially
Toxic Chemicals (IRPTC PC) - Data

Joint Expert Committee on Food
Additives (JECFA) - Monographs
and Evaluations
Joint Meeting On Pesticide
Residues (JMPR) - Monographs of
Toxicological Endpoints


Proprietor


EPA Office of Prevention,
Pesticides, and Toxic
Substances; EPA, Office of
Science Coordination and Policy

EPA

EPA/IARC

National Library of Medicine;
Created by EPA; maintained by
NIH's NLM


Health Canada


EPA Office of Water

World Health Organization,
International Labour
Organisation, United Nations
Environment Programme,
Canadian Centre for
Occupational Health and Safety

EPA NCEA

EPA

EPA Office of Research and
Development
United Nations Environment
Programme; UNEP, Division of
Technology, Industry, and
Economics
World Health Organization, Food
and Agriculture Organization
World Health Organization, Food
and Agriculture Organization
Assessment Factor Evaluation
Relevance


!i

Jo
Y


N

N

N


N


N


N


N

N

Y
N

N
N


_ 0)
"c 0)
o) b

Q- 8
O
Y


Y

N

N


N


N


N


N

Y

N
Y

N
N


^ L1J

l|
Y


N

N

Y


Y


Y


Y


Y

Y

N
Y

Y
Y


|l

0)
X
Y


N

Y

N


N


N


N


N

N

N
N

N
N





This source is considered relevant for the CCL
Universe because it contains data elements
derived from toxicological studies and unique
elements derived for measurements of
contaminants in water, providing an indicator of
occurrence.
This source is considered relevant because it
contains geographical and water quality data,
providing an indicator of potential occurrence.
This source is considered relevant for the CCL
Universe because it contains information on
mutagenicity, which may be an indicator of
potential health effects.
This source is considered relevant for the CCL
Universe because it contains information on
mutagenicity, which may be an indicator of
potential health effects.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.

This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.

This source is considered relevant for the CCL
Universe because it contains data elements
(RfDs)from toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies and environmental fate data,
providing an indicator of potential occurrence.

Universe because it contains information that is
related to potential exposure.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies and environmental fate data,
providing an indicator of potential occurrence.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
Redundancy





This source is not
redundant.


This source is not
redundant.

This source is not
redundant.

This source is not
redundant.





d d t


This source is not
redundant.

TrV


This source is not
redundant.

This source is not
redundant.
This source is not
redundant.

This source is not
redundant.
This source is not
redundant.
Completeness
'o

o ®
5 '1

D 0)
r
N


Y

Y

Y


Y


Y


Y


Y

N

N
Y

Y
Y
o

•z. E
= 2

1 f
$ a:
Y


Y

Y

Y


Y


Y


Y


Y

Y

Y
Y

Y
Y
Retrievability


E
I

&
Tabular


Tabular

Monographic

Monographic


Monographic


Monographic


Monographic


Monographic

Monographic

Tabular
Tabular

Monographic
Monographic


.2
"S.
~

D
N


N

N

N


N


N


N


N

N

N
N

N
N





Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supp emen a source.

Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.

This source has been withdrawn; it is no longer
available online.

This source does not meet retrievability criteria
because the data are not formatted for automated

This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.

This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.

This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria. This
source has data in a tabular format, but it is not
formatted to allow complete data extraction with
automated retrieval.
This source does not meet retrievability criteria. This
source has data in a tabular format, but it is not
formatted to allow complete data extraction with
automated retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                                  Appendix 3. CCL 3 Universe Supplemental Data Sources
Source Identifi


ID




64
76
78

84


88


89

91

94

92

109

111


113



Data Source Name


Endocrine Disrupter Priority Setting
Database (EDPSD)
Environmental Monitoring and
Assessment Program (EMAP)
Genetic Activity Profiles (GAP)
Database
GENE-TOX
Guidelines for Canadian Drinking
Water Quality (CADW): Supporting
Documentation

Health Advisory Documents

Health and Safety Guides - World
Health Organization, ILO, UNEP,
CCOHS
Health Effects Assessment
Summary Tables (HEAST) - EPA
NCEA
High Production Volume (HPV)
Challenge Program Robust
Summaries and Test Plans
Human Exposure Database System
(HEDS)
International Register of Potentially
Toxic Chemicals (IRPTC PC) - Data
Profiles -UNEP Chemicals
Joint Expert Committee on Food
Additives (JECFA) - Monographs
and Evaluations
Joint Meeting On Pesticide
Residues (JMPR) - Monographs of
Toxicological Endpoints


Lj


N

N
N
N

N


N


N

N

N

N

N

N


N

$
t
0)
a.
o
a.

U
Y

N
N
N

N


N


N

N

Y

N

Y

N


N


CO
I


N

N
N
N

Y


Y


N

N

N

N

N

N


N


o
a.
ai
_o
.Q
m

N

N
N
N

N


N


N

N

N

N

N

N


N


2
'E
<3
O
O

87000

170
>750
>3000

197


181


109

200

>180

46

8000

1050


1000


c
1
32
8.

Potential
Endocrine
disrupters
Chemicals
Chemicals
Chemicals



Chemicals,
Microbes,
Inorganics

Chemicals

Chemicals

High Production

Metals, VOCs,
Pesticides

Chemicals

Chemicals


Pesticides



Type of Data Elements


Name, CASRN, HE and Occurrence data

Assemblage Counts, Chlorophyll Data, Assemblage Metrics, Counts Data, Diatom Data,
Identification Codes Data, Invertebrate Metrics, Metals, Site Information, Streams
Chemistry, Watershed Characteristics, Benthic Data, Fish Data, Fish Tissue Contaminants, G
Chemical name, CAS registry number, test code, test endpoint, test results, highest ineffective
dose (HID) or lowest effective dose (LED), reference number, reference citation
Name, CASRN, Mutagenicity Studies, Assay Type, Evaluation Results, Panel Report, Reference,
Species/Cell Type, Species/Cell Type Sex, Taxonomic Name & Assay

Name, synonyms, formula, iMAC, MAC, IARC cancer class, ADI, MTD, LDx, NO(A)EL, lifetime risk

Dose response assessments, Exposure from drinking water, Exposure from environmental media
other than water, Hazard identification, Physical and chemical properties, Regulatory
determination and characterization of risk, Toxicokinetics, Uses and environme
CASRN, Physical/Chemical, Environmental Fate, Production/Use, Occurrence, Ecological Toxicity,
Species, Route, Dose, Frequency, Duration, Critical Effect, CLV, ERL, MAC, MR(es)L, MXL,
RECL, STEL, TWA, LCx, LDx, LO(A)EL
Name, CASRN, Slope factor, Unit risk, RfD, RfC

Name, CASRN, Structure, Acute Toxicity (LD50), Repeated Dose Toxicity (NOAEL, LOAEL),
Genetic Toxicity in vitro, Genetic Toxicity in vivo, Reproductive Toxicity, Developmental Toxicity,
Acute Ecotoxicity (fish and aquatic invertebrates), Photodegradation,
Contaminant Class, Sampling Method, Sampling Device, Sample Type Code, Concentration,
Qualifier, Method Det. Limit, Data Quality Flag, State, County, Samp. Location, Household ID,
Respondents, Sample ID, Samp. Start Date, Samp. End Date

Environmental fate, Production, Mammalian Toxicity

Summary of evaluations, Recommended dietary allowance, Carcinogenicity, Mutagenicity,
Reproduction, Teratogenicity, Acute Toxicity, Short term studies, Long-term studies, Observations
in humans, Immune response, Ototoxicity, Microbiological effects

Name, CASRN, Formula, Structure, ADI, RfD, DW GLs, pTDI, RfD, LDx, NO(A)EL, LO(A)EL

0)
*5
11
•£ LJ.
S.

None

Unknown
None
As Needed
No
Mandated
Schedule

As Needed




Unknown

As Needed

As Needed

As Needed

Unknown


As Needed


~° "o
1 1
Q. +*
"I

2002

2002
1999
2003

2002


2002


2002

2002

2003

2002

2002

1974


2003


-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                                  Appendix 3. CCL 3 Universe Supplemental Data Sources




ID


114
139

140

143
146
148


149


150
156


152

163

161
160


Data Source Name


Laboratory Chemical Safety
Summaries (LCSS) - Howard
Hughes Medical Institute and
National Academy of Science
National Health and Nutrition
Examination Survey (NHANES)

National Human Adipose Tissue
Survey (NHATS)

National Institute for Occupational
Safety and Health (NIOSH) - Index
of Occupational Health Guidelines
for Chemical Hazards
National Occupational Exposure
Survey (NOES)
National Sanitary Foundation (NSF)
- Additives Standards 60 and 61


National Sediment Inventory (NSI)


National Toxicology Program (NTP)
Health and Safety Profiles
Office of Pollution Prevention and
Toxics (OPPT) Chemical Fact


Organisation for Economic Co-
operation and Development
(OECD) Integrated HPV Database

Palm Top Emergency Action for
Chemicals (PEAC-CW System) -
Federal Technical Support Working
Group
Permit Compliance System (PCS)
Database
Persistent, Bioaccumulative, and
Toxic Profiles (PBT Profiler)


Proprietor


Howard Hughes Medical
Institute, National Academy of
Science
CDC National Center for Health
Statistics

EPA Office of Toxic Substances

CDC National Institute for
Occupational Safety and Health
(NIOSH)
CDC National Institute for
Occupational Safety and Health
(NIOSH)
National Sanitary Foundation


EPA Office of Water, OST


National Toxicology Program;
NIH
EPA Office of Pollution
Prevention and Toxics


Organisation for Economic Co-
operation and Development

Technical Support Working
Group

EPA OECA
EPA (OPPT), Environmental
Science Center, Syracuse
Research Corporation
Assessment Factor Evaluation
Relevance


!i

Jo
N
N

N

N
N
N


N


N
N


N

N

N
N


_ 0)
"c 0)
o) b

Q- 8
O
N
Y

Y

N
Y
N


Y


N
Y


Y

N

Y
Y


^ L1J

II
Y
N

N

Y
N
Y


N


Y
Y


Y

Y

N
N


|l

0)
X
N
N

N

N
N
N


N


N
N


N

N

N
N





This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in either the blood or urine,
providing an indicator of occurrence.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in human adipose tissue, providing
an indicator of occurrence.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains information that is
related to potential exposure.
This source is considered relevant for the CCL
Universe because it contains information on
health effects standards for drinking water.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in sediments (which can contribute
contaminants to drinking water), and can indicate
potential occurrence.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies and environmental fate data,
providing an indicator of potential occurrence.
This source is considered relevant for the CCL
Universe because it is a list of HPV chemicals,
which may indicate possible occurrence. It also
contains data elements from toxicological
studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.

This source is considered relevant for the CCL
Universe because it contains information on
discharge of waste to rivers, which may indicate
potential occurrence.
This source is considered relevant for the CCL
Universe because it could be a source of
information on persistence, providing an indicator
of occurrence.
Redundancy





This source is not
redundant.
This source is not
redundant.

This source is not
redundant.

This source is not
redundant.
This source is not
redundant.
This source is not
redundant.

TrV

'

This source is not
redundant.
This source is not
redundant.


This source is not
redundant.

This source is not
redundant.

This source is not
redundant.
This source is not
redundant.
Completeness
'o

o ®
5 '1

D 0)
r
Y
Y

Y

Y
Y
Y


N


Y
N


Y

N

Y
N
o

•z. E
= 2

1 f
$ a:
Y
Y

Y

Y
Y
Y


Y


Y
Y


Y

Y

Y
Y
Retrievability


E
I

&
Monographic
Monographic

Monographic

Monographic
Monographic
Monographic


Monographic


Monographic
Monographic


Monographic

Tabular

Tabular &
Monographic
Tabular/Model


.2
"S.
~

3
N
N

N

N
N
Y


N


N
N


N

Y

N
N





This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated

This source does not meet retrievability criteria
because the data are not formatted for automated

This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval, however some tabular data have been
obtained from ERG.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval, and it is only available through a
subscription.

This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.

This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated


This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.

This source does not meet retrievability criteria
because it is only available through a subscription.

Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.
This source does not meet retrievability criteria. The
source does not contain data; it is a model that might
be used to generate estimates.

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                                  Appendix 3. CCL 3 Universe Supplemental Data Sources
Source Identifi


ID


114
139
140

143

146
148
149
150

156


152

163

161


160



Data Source Name


Laboratory Chemical Safety
Summaries (LCSS) - Howard
Hughes Medical Institute and
National Academy of Science
National Health and Nutrition
Examination Survey (NHANES)
National Human Adipose Tissue
Survey (NHATS)
National Institute for Occupational
Safety and Health (NIOSH) - Index
of Occupational Health Guidelines
for Chemical Hazards
National Occupational Exposure
Survey (NOES)
National Sanitary Foundation (NSF)
- Additives Standards 60 and 61
National Sediment Inventory (NSI)
National Toxicology Program (NTP)
Health and Safety Profiles
Office of Pollution Prevention and
Toxics (OPPT) Chemical Fact
Sheets
Organisation for Economic Co-
operation and Development
(OECD) Integrated HPV Database
Palm Top Emergency Action for
Chemicals (PEAC-CW System) -
Federal Technical Support Working
Group
Permit Compliance System (PCS)


Persistent, Bioaccumulative, and
Toxic Profiles (PBT Profiler)



Lj


N
N
N

N

N
N
N
N

N


N

N

N


N

$
t
0)
a.
o
a.

U
N
N
N

Y

N
N
N
N

N


Y

N

N


Y


CO
I


N
N
N

N

N
N
N
N

N


N

N

N


N


o
a.
ai
_o
.Q
ffi

N
N
N

N

N
N
N
N

N


N

N

N


N


2
'E
<3
O
O

88
27
150

675

Unknown
NA
220
NA

31


5,235

10000

NA


100000


c
1
32
8.

Laboratory
chemicals
Chemicals
Chemicals

Chemicals

Chemicals
Chemicals
Chemicals
Chemicals

Chemicals


Chemicals

Toxic chemicals

Chemicals

Chemicals
(persistent,
bioaccumulative,
toxic)


Type of Data Elements


Substance, Formula, Physical Properties, Odor, Vapor Density, Vapor Pressure, Flash Point,
Autoignition Temperature, Toxicity Data, Major Hazards, Toxicity, Flammability and Explosibility,
Reactivity and Incompatibility, Storage and Handling, Accidents, D
CAS RN, Parameter, Detection limit, Number of samples, Mean, Median, 5th percentile, 95th
percentile, Percent above detection limit
Chemical name, CAS RN, Year, Number of Analyses, Arithmetic/Geometric Mean, Lowest
Arithmetic/Geometric Mean, Number of Analyses with Lowest Arithmetic/Geometric Mean, Highest
Arithmetic/Geometric Mean, Number of Analyses with Highest Arithmetic/Geometric
Formula, Structure, Appearance and odor,
Physical Data, Reactivity, Flammability, OSHA PEL, NIOSH REL, ACGIH TLV, Rationale for limits,
Routes of exposure, Summary of toxicology, Signs and symptoms of exposure, Emergency
procedures, Exposure Sources and
CAS RN, Name, Standard industrial classification (SIC) code, Number of workers exposed to the
substance, Number of facilities handling the material
Unknown
Analyte sampled, Mean, Max, Median, Min, Measured/estimated value, Fraction organic carbon,
Nondetectflag, Number of samples, Units
BP, Carcinogen! city, Critical effects, Dose, Duration, GenTox, GMM Abstract, GMM Care, GMM
GenTox, GMM Neo, GMM Nonneo, Hazard class, MP, Mutation Data, Other toxicity data, Path,
RACE Abstract, Rationale for testing, RDGT Abstract, Reactivity, Route, SAX
What is the contaminant, how is it used, and how might 1 be exposed? What happens to the
contaminant in the environment? How does the contaminant affect human health and the
environment? What EPA program offices regulate the contaminant, and under what la

Name, CASRN, SIDS status

"Published toxicity levels"

Facility, Address, Activity Status, Permit Type, Issued Date, Expired Date, USGS Hydro Basin,
Stream Segment, Flow, Receiving Stream Class, Federal_grant_ind, Receiving Waters, Final
Limits Ind Pretreatment Code, Sludge Information, Permit Documents, Insp

Predicted persistence (half life) in air, water, soil, and sediment, Bioaccumulation (BCF), Fish ChV,
Includes structural information

0)
*5
11
« u.
S.

Unknown
Unknown
Finished

As needed

Finished
Every five
years
As Needed
Unknown

Finished


iy

As Needed

Monthly


As Needed


~° "o
1 1
Q. +*
"I

Unknown
2002
1990

1995

1983
2002
1993
2003

1994


2000

Unknown

2004


2003


-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                                  Appendix 3. CCL 3 Universe Supplemental Data Sources




ID


159

262


168



269


170





180

176

1/9

232
182
189


Data Source Name


Pesticide Action Network (PAN)
Pesticide Database

Pesticide Handler Exposure


Pesticide Product Information



Pesticide Tolerance Index System


Priority Substances Assessment
Program - Health Canada

Priority-based Assessment of Food
Additives (PAFA) Database


Registry of Toxic Effects of
Chemical Substances (RTECS)

Reregi strati on Eligibility Decision
Documents (REDDs) - EPA OPP
Rijksinstituut voor Volksgesondheid
en Milieu (RIVM) Maximum
Permissible Risks (MPRs) Report
Safe Drinking Water Information
System (SDWIS)
Screening Information Data Sets
(SIDS) - Organisation for Economic
Co-operation and Development
(OECD)
Source Ranking Database (3RD)


Proprietor


Pesticide Action Network

EPA


EPA



EPA


Health Canada

FDA Center for Food Safety and
Applied Nutrition


CDC National Institute for
Occupational Safety and Health
(NIOSH)

EPA Office of Pesticide
Programs
Rijksinstituut voor
Volksgesondheid en Milieu
(RIVM), The Netherlands
EPA
International Programme for
Chemical Safety, United Nations
Environmental Program;
UNEP/IRPTC in Geneva,
Switzerland
EPAOPPT
Assessment Factor Evaluation
Relevance


!i

Jo
N

Y


N



N


N





N

N

N

Y
N
N


_ 0)
"c 0)
o) b

Q- 8
O
N

N


N



N


N





N

N

N

N
N
Y


^ L1J

II
Y

N


N



Y


Y





Y

Y

Y

N
Y
N


|l

0)
X
Y

N


Y



N


N





N

N

N

N
N
Y





This source is considered relevant for the CCL
Universe because it contains health effects data.

This source is considered relevant for the CCL
Universe because it contains information on
human exposure to pesticides.

This source is considered relevant for the CCL
Universe because it contains an indicator of
possible health effects.


This source is considered relevant for the CCL
Universe because it contains information on
pesticide exposure tolerances.

This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements
directly from and derived from toxicological
studies.

This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.

This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in water, demonstrating
occurrence.
This source is considered relevant for the CCL
Universe because it contains data elements
(LDx, NO(A)EL) from toxicological studies.
This source is considered relevant for the CCL
Universe because it has elements that may
indicate possible occurrence and/or possible
health effects.
Redundancy





This source is not
redundant.

This source is not

This source is
redundant with NPIRS
(source 261); however,
NPIRS is a subscription
source.
This source is
redundant with NPIRS
(source 261); however,
NPIRS is a subscription
source.
This source is not
redundant.

This source is not
redundant.


This source is not
redundant.

This source is not
redundant.



This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
Completeness
'o

o ®
5 '1

D 0)
r
N

Unknown


Unknown



Unknown


Y





Y

Y

Y

Unknown
Y
Y
o

•z. E
= 2

1 f
$ a:
Y

Y


Y



Y


Y





Y

Y

Y

Y
Y
Y
Retrievability


E
I

&
Tabular

Unknown


Monographic



Tabular


Monographic

Tabular


Monographic
(can be
extracted in
tabular
format)
Monographic

Monographic

Tabular
Monographic
Tabular


.2
"S.
~

3
N

N


N



N


N





Y

N

N

N
N
N





This source does not meet retrievability criteria. This
source has data in a tabular format, but it is not
formatted to allow complete data extraction with
automated retrieval.
Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.

Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.


Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.

This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.

This source does not meet retrievability criteria
because it is only available through a subscription.


This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.

This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria. The
source does not contain data; it is a model that might
be used to generate estimates.

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                                  Appendix 3. CCL 3 Universe Supplemental Data Sources
Source Identifi


ID



159
262
168


170
157
180
176


1/9

232

182

189


Data Source Name



Pesticide Action Network (PAN)
Pesticide Database
Pesticide Handler Exposure
Database
Pesticide Product Information
System (PPIS)
Pesticide Tolerance Index System

Priority Substances Assessment
Program - Health Canada
Priority-based Assessment of Food
Additives (PAFA) Database
Registry of Toxic Effects of
Chemical Substances (RTECS)
Reregistration Eligibility Decision
Documents (REDDs)- EPA OPP

Rijksinstituut voor Volksgesondheid
en Milieu (RIVM) Maximum
Permissible Risks (MPRs) Report
Safe Drinking Water Information
System (SDWIS)
Screening Information Data Sets
(SIDS) - Organisation for Economic
Co-operation and Development
(OECD)
Source Ranking Database (3RD)


Lj



N
N
Y
N

N
N
N
N


N

N

N

N
$
•c
0)
a.
o
a.
1

U
N
N
N
N

N
N
N
N


N

N

N

N

CO
£



N
N
N
N

N
N
N
N


N

N

N

N

o
a.
ai
_o
.Q
m


N
N
N
N

N
N
N
N


N

N

N

N

£
'E
<3
O


6400
Unknown
90000
Unknown

69
3000
156485
176


50

Unknown

92

1377

c
1
32
8.


Pesticides
Pesticides
Pesticides
Pesticides

Chemicals
Food Additives
Chemicals
Pesticides
Soil Contaminants
(Metals,
Aromatics,
Chlorinated HCs,
ia.)
Chemicals

High Production
Volume

Chemicals


Type of Data Elements



Chemical Name, CAS Number, U.S. EPA PC Code, CA DPR Chem Code, Molecular Weight, Use
Type, Chem Class, Route of Exposure, Symptoms, First Aid, PAN Bad Actor Chemical, Acute
Toxicity, Carcinogen, Cholinesterase Inhibitor, Ground Water Contaminant, Developm
Pesticide exposure data
Name, CASRN, Registrant name and address, Chemical ingredients, Toxicity category, Product
names, Distributor brand names, Site/pest uses, Pesticidal type, Formulation code, and
Registration status
Unknown

Name, Synonyms, CASRN, Formula, BMC, BMD, ENEV, MTD, CTV, ECx, ICx, LDx, LO(A)EL,
NO(A)EL, SMR, TumCx, TumDx
Genetic Toxicity and Cytotoxicology, Acute Toxicology, Oral Toxicology, HNEL, Toxicological
effect, Exposure, ADI, LD High, LEL
LDx, NOAEL, LOAEL, Reproductive/ Developmental, Mutation, Irritation, Tumorigenic data
Name, Synonyms, DWLOC, PAD, RfD, MCL, SF, LCx, LDx, LO(A)EL, MOE, NO(A)EL, HOT

Absorption Factors, ADI, Backgmd Exposure, CR, Crinhal reliability, Crinhal value, Croral
reliability, Croral value, Dose Ranges, HUM-TOX SCC, IARC Cancer Group, LO(A)EL, MAC,
MPR: oral, inhalation, MRL, MTD, NO(A)EL, Old MPR?, pCRinhal reliability, pCRi
Water System Name, Principal County Served, Population Served, Primary Water Source Type,
System Status, Water System ID, Concentration, Violations

Name, Formula, Synonyms, CASRN, Other IDs, ADI, ECx, LCx, LDx, NO(A)EL

Unknown
0)
*5
11
• U.
°-

As Needed
Unknown
Weekly
None

As Needed
As Needed
Quarterly
As Needed



report.
Unknown

As Needed

None

~° "o
1 1
Q. +*
5 1
' '

2002
Unknown
2004
2003

2002
2003
2003
2003


2001

Unknown

2004

2003

-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                                  Appendix 3. CCL 3 Universe Supplemental Data Sources




ID


190


192

194
202

181


240
208
250
213
220
229

85


40



Data Source Name


State Drinking Water Data Sets

State of New Jersey Hazardous
Substances Right to Know Fact
Sheets
STN - CHEMLIST/HCHEMLIST -
Regulated Chemical Listing
STORET - STORage and RETrieval

Superfund Contract Laboratory
Program (SCLP) Water/Soil Data


The Open Practical Knowledge
Acquisition Toolkit (TOPKAT)
TOMES PLUS, MICROMEDEX-
Thomson-Micromedex
Total Exposure Assessment
Methodology Study (TEAM)
TSCATS - Toxic Substances
Control Act Test Submissions
US Army Center for Health
Promotion and Medicine Detailed
Chemical Fact Sheets
Water Environment Research
Foundation (WERF) Toxicity
Datasheets
WHO Guidelines for Drinking Water
Quality: Chemical Aspects: Index of
Chemicals

WHO Recommended Classification
of Pesticides by Hazard (CPH)



Proprietor


EPA OGWDW; The Cadmus
Group, Inc.


State of New Jersey

Chemical Abstracts Service
EPA

Operations/Data Quality Center
(AOC) in the Office of
Emergency and Remedial
Response (OERR)

Accel rys
Thomson Micromedex
EPA
Syracuse Research Corporation;
Developed and maintained by
SRC for EPA
U.S. Army Center for Health
Promotion and Medicine
UK Water Industry Research &
Wrc-NSF Ltd.

World Health Organization

International Programme for
Chemical Safety, World Health
Organization, International
Labour Organisation, United
Nations Environment Programme
Assessment Factor Evaluation
Relevance


!i

Jo
Y


N

N
Y

Y


N
N
N
N
N
N

N


N



_ 0)
"c 0)
o) b

Q- S
O
N


N

N
N

N


N
N
N
N
N
N

N


N



^ L1J

l|
N


Y

N
N

N


N
Y
N
Y
Y
Y

Y


Y



|l

0)
X
N


Y

N
N

N


Y
N
Y
N
N
N

N


N






This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in water, demonstrating
occurrence. Most data are available for
regulated contaminants. Some data are
available for unregulated contaminants.
This source is considered relevant for the CCL
Universe because it contains information on
carcinogen! city and potential health effects.
This source is considered relevant for the CCL
Universe because it contains a list related to
health effects or occurrence.
This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in water, demonstrating
occurrence.

This source is considered relevant for the CCL
Universe because it contains measurements of
contaminants in water, demonstrating
'

Universe because it could be a source of
information on potential health effects.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains information on
potential health effects.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.
This source is considered relevant for the CCL
Universe because it could be a source of
information on health effects.
This source is considered relevant for the CCL
Universe because it contains data elements from
toxicological studies.

This source is considered relevant for the CCL
Universe because it contains data elements
derived from toxicological studies.

Redundancy





This source is partially
redundant, as it is
mostly available as part
of NCOD- Six Year
(source 136).

d d t

This source is not
redundant.
This source is not
redundant.

This source is not
redundant.


This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.
This source is not
redundant.




This source is not
redundant.

Completeness
'o

o ®
5 '1

D 0)
r
N


Y

Unknown
N

Y


Unknown
Y
Unknown
Y
Y
Y

Y


Y

o

•z. E
= 2

1 f
$ a:
Y


Y

Y
Y

Y


Y
Y
Y
Y
Y
Y

Y


Y

Retrievability


E
I

&
Tabular


Monographic

Tabular
Tabular/
Monographic

Monographic


Model
Monographic
Tabular
Monographic
Monographic
Tabular

Monographic


Tabular/
Monograph



.2
"S.
~

D
N


N

Y
N

N


Y
Y
N
N
N
Y

N


N






Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.

This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because it is only available through a subscription.
Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.

Data are retrievable by EPA but require special
processing and analysis for CCL use. Designated as
a supplemental source.

This source does not meet retrievability criteria. The
source does not contain data; it is a model that might
be used to generate estimates. The source is only
available through a subscription.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval, and it is only available through a
subscription.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.
This source does not meet retrievability criteria
because it is only available through a subscription.
This source does not meet retrievability criteria
because the data are not formatted for automated
retrieval.

This source does not meet retrievability criteria
because, with the exception of the classifications, it
is not formatted for automated retrieval.


-------
EPA-OGWDW
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
    August 2009
                                                  Appendix 3. CCL 3 Universe Supplemental Data Sources
Source Identifi


ID


190
192
194
202
181
240
208
250
213
220


229


85

40


Data Source Name


State Drinking Water Data Sets
State of New Jersey Hazardous
Substances Right to Know Fact
Sheets
STN - CHEMLIST/HCHEMLIST -
Regulated Chemical Listing
STORET - STORage and RETrieval
Superfund Contract Laboratory
Program (SCLP) Water/Soil Data
The Open Practical Knowledge
Acquisition Toolkit (TOPKAT)
TOMES PLUS, MICROMEDEX-
Thomson-Micromedex
Total Exposure Assessment
Methodology Study (TEAM)
TSCATS - Toxic Substances
Control Act Test Submissions
US Army Center for Health
Promotion and Medicine Detailed
Chemical Fact Sheets
Water Environment Research
Foundation (WERF) Toxicity
Datasheets
WHO Guidelines for Drinking Water
Quality: Chemical Aspects: Index of
Chemicals
WHO Recommended Classification
of Pesticides by Hazard (CPH)


Lj


N
N
Y
N
N
N
N
N
N
N


N


N

N
$
t
O>
a.
o
a.

U
N
N
N
N
Y
N
N
N
N
N


N


N

N

CO
I


N
N
N
Y
N
N
N
N
N
N


N


N

N

o
a.
ai
_o
.Q
ffi

N
N
N
N
N
N
N
N
N
N


N


N

N

2
'E
<3
O
O

>60
1000
NA
NA
150
NA
4000
30
8000
24


450


143

500

c
1
32
8.

Mostly Regulated
Chemicals
Chemicals
Chemicals
Chemicals,
Biologicals,
Physical Agents
Chemicals
Chemicals
Chemicals
Chemicals
Chemicals
Weaponry Agents


Chemicals


Chemicals

Pesticides


Type of Data Elements


Drinking water occurrence concentrations
Field, Common Name, CAS RN, DOT Number, RTK Substance Number, Date, Revision, Hazard
Summary, Workplace Exposure Limits, Acute Health Effects, Chronic Health Effects, Cancer
Hazard, Reproductive Hazard, Other Long-term Effects
Substance identity information, inventory status, source of information, and summaries of
regulatory activity, reports, and other compliance information
Estimated, Nitrogen, ammonia (NH3) as NH3 (mg/l), Estimated, Fecal Coliform (#/100ml),
Estimated Total Coliform (#/100ml)
Mean, Min, Max, Median, Measured/Estimated Concentrations
SMILES, Compund Name, Primary ID, Secondary ID, Rodent Carcinogenicity, Ames Mutagenicity,
Rat Oral LD50, Rat Chronic LOAEL, Developmental Toxicity Potential, Skin Sensitization, Fathead
Minnow LC50, Daphnia Magna EC50, Weight of Evidence Rodent Carcinoge
Identification & Synonyms, Range of Toxicity, Toxicity/Biomedical Effects, Environmental
Fate/Exposure Potential, Chronic Health Hazard Assessments for Non-Carcinogenic Effects,
Carcinogenicity Assessments for Lifetime Exposure
Name, CAS RN, Central tendency, Units, Method of Measurement, Number of samples,
Percent of the samples that were measurable, Population, Water Type, Location, Season
CAS RN, Name, Study Purpose, Organism, Rte Admin, Test, Ref
Chemical Formula, Description, Overexposure Effects, Reactivity Data, Toxicity Values, Exposure


Unknown

Name, synonym, formula, MP, BP, density, VP, water solubility, Log Kow, odor thresholds, use,
environmental fate, ADI, CR, GV, IARC cancer class, TDI, NO(A)EL, LO(A)EL, LDx, HRL,
reproductive, embryotoxicity, teratogenicity, mutagenicity
Dose, Critical Effect, BMC, BMD, ENEV, Cancer Group, TC(A), CTV, ECx, ICx, LCx, LDx,
LO(A)EL, NO(A)EL
0)
*5
11
« u.
S.

Finished
As Needed
Weekly
As Needed
As Needed
NA
Unknown
None
As Needed
As Needed


2/year


As Needed

Semi-
annually

~° "o
1 1
a. **
"I

1997
January
2004
2003
2003
2002
NA
2002
1999
2002
1998


2003


1996

2002

-------
EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
                        Appendix 4.  CCL 3 Data Source Descriptions
Data Source Name
Identification Number
Data Source Description
10th Report on Carcinogens - NTP
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
1

The Report on Carcinogens (RoC) is an informational scientific and public health
document that identifies and discusses substances (including agents, mixtures, or exposure
circumstances) that may pose a carcinogenic hazard to human health. It serves as a
meaningful and useful compilation of data on (1) the carcinogenicity (whether it causes
cancer), genotoxicity (whether it causes damage to genes), and biologic mechanisms (how it
works in the body) of the listed substances in people and/or in animals, (2) the potential for
human exposure to these substances, and (3) Federal regulations to limit exposures. The
RoC does not present quantitative assessments of the carcinogenic risk of these
substances. Listing of substances in the RoC, therefore, does not establish that these
substances present carcinogenic risks to individuals in their daily lives. Such formal risk
assessments are the  responsibility of the appropriate federal, state, and local health
regulatory and research agencies. The substances listed in the RoC are either known or are
reasonably anticipated to cause cancer in humans under certain exposure  circumstances.
(description from website)

Department of Health and Human Services - National Toxicology Program

Thomas J. Goehl,  PhD
EHP
NIEHS/NIHMDEC-15
PO Box 12233
Research Triangle Park, NC 27709-2233
Phone:919-541-7961
Fax: 919-541-0273
E-mail: goehl@niehs.nih.gov

Name, CASRN, IARC cancer class, vapor pressure, vapor density, MP, BP, flash point,
use, production, critical effect, exposure potential, releases, occupational exposure limits

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://ehp.niehs.nih.aov/roc/toc10.html
Data Source Name
Identification Number
Data Source Description
Proprietor
8(e) TRIAGE Chemical Studies Database - OPPT

2

Searchable database of scientific studies on the health and environmental effects of toxic
chemicals related to Section 8(e) of TSCA.

In order to help reduce the risks of chemicals in the environment, EPA recognizes the
importance of providing the public with access to the information collected under TSCA and
other environmental statutes. One important information gathering tool under TSCA is found
in Section 8(e). Under Section 8(e), manufacturers, importers, and distributors of chemical
substances and mixtures are required to inform EPA of studies that reasonably support the
conclusion that the chemicals present a "substantial risk of injury" to human health or the
environment. In 1991 OPPT initiated the Compliance Audit Program (CAP). The CAP was a
voluntary program that encouraged companies to audit their files for information that was
required by 8(e). It provided  reduced monetary penalties for companies submitting studies
that were past the statutory submittal deadline. EPA received about 10,000 submissions
under the CAP,  in addition to the approximately 400 non-CAP 8(e)s the Agency receives
each year. The Database includes the majority of the CAP and non-CAP submissions
received after 1991. (description from website)

EPA Office of Prevention, Pesticides, and Toxic Substances
                                                         A4-1

-------
EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Linda Goodman
Information Products Section, OPPT
7407M
US EPA Headquarters
Ariel Rios Building
1200 Pennsylvania Avenue, N. W.
Washington, DC 20460

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.epa.gov/docs/8e triad/
Data Source Name


Identification Number
Data Source Description
Proprietor

Contact Information


Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
Aerometric Information Retrieval System/Air Quality Subsystem
(AIRS/AQS)
AIRS AQS is a searchable database of hourly and annual average air emissions and
monitoring data from national (i.e., all 50 States, Puerto Rico, and the U.S. Virgin Islands)
and international monitoring stations. AIRS AQS provides reporting information from three
databases (Aerometric Information Retrieval System (AIRS), National Emissions Trends
(NET), and National Toxics Inventory (NTI)) for the six criteria pollutants (i.e., carbon
dioxide, lead, nitrogen dioxide, ozone, particulate matter 10 and 2.5, and sulfur dioxide) and
188 hazardous air pollutants. The three databases provide ambient concentrations of criteria
air pollutants at monitoring sites; annual emissions of criteria air pollutants from point, area,
and mobile sources; and estimates of annual emissions of hazardous air pollutants from
point, area, and mobile sources, (description from website)

EPA Office of Air and Radiation

If you need assistance accessing any of the material in AQS,  User Support is provided
through the EPA Call Center. The toll free number is 866-411-4EPA (866-411-4372). Please
contact them first with any questions about using the AQS application.

name, air quality standard, number observations, max values (1 hour), number exceedences
 (1 hour), max values (3 hour), number exceedences (3 hour), max values (8 hour), number
exceedences (8 hour), max values (24 hour), number exceedences (24 hour), annual mean,
number exceedences (year), quarterly averages, site ID, site address, city, county, state,
EPA Region

This source is considered relevant for the CCL Universe because it contains information on
air emissions, which may indicate potential occurrence.

It meets considerations because it is peer reviewed.

This source is redundant with Idaho Toxic and Hazardous Substances - Idaho Division of
Building Safety (source 100).

This source meets retrievability criteria because it is in tabular format.

http://www.epa.aov/ttn/airs/airsaas/aasweb/aqswebhome.htm
Data Source Name

Identification Number
Data Source Description
AGRICultural OnLine Access (AGRICOLA)
AGRICOLA (AGRICultural OnLine Access) is a bibliographic database of citations to the
agricultural literature created by the National Agricultural Library (NAL) and its cooperators.
Production of these records in electronic form began in 1970, but the database covers
                                                         A4-2

-------
EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Proprietor

Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation

Retrievability Explanation

Source URL
materials in all formats, including printed works from the 15th century. The records describe
publications and resources encompassing all aspects of agriculture and allied disciplines,
including animal and veterinary sciences, entomology, plant sciences, forestry, aquaculture
and fisheries, farming and farming systems, agricultural economics, extension and
education, food and human nutrition, and earth and environmental sciences. Although the
AGRICOLA database does not contain the materials, thousands of AGRICOLA records are
linked to full-text documents online, with new links added daily,  (description from website)

National Agricultural Library (NAL) and its cooperators, part of the U.S. Department of
Agriculture's (USDA) Agricultural Research Service

AGRICOLAhelp@nal.usda.gov

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers, authors, title, journal, date of publication

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.

This source is redundant with Cambridge Scientific Abstracts (source 15), but that source is
a subscription, whereas this source is free of charge.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://aaricola.nal.usda.gov/
Data Source Name

Identification Number
Data Source Description


Proprietor
Contact Information

Type of Data Elements
Relevance Explanation

Completeness Explanation

Redundancy Explanation

Retrievability Explanation

Source URL
All the Virology on the WWW

5

This web site, run by a medical researcher, provides links to a broad variety of virology-
related resources on the Internet. The site includes a "Big Picture Book of Viruses," which
provides web based visuals, but may also be used as a taxonomy resource.

Virology.net; Dr. David M. Sander (a medical researcher; corporate sponsorship)

David M. Sander, Ph.D.
david.sander@virology.net

links to virology research and data sites, specific virus servers and information, AIDS
information/research,  Plant virus servers and information, viral diseases, vaccines, and
treatments, organizations and groups of interest to virologists, educational resources, general
virology information and news, and related internet resources for virologists; virus pictures

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.virology.net
Data Source Name

Identification Number
Data Source Description
Alternate Crops and Systems (ARS) Pesticide Properties Database
The ARS Pesticide Properties Database (PPD) has been developed to provide water quality
modelers and managers a list of the pesticide properties most important for predicting the
potentials of pesticides to move into ground and surface waters under a range of weather
and soil conditions.

The ARS PPD is a compendium of chemical and physical properties of 334 widely used
pesticides. Information included in the database focuses on 16 of the most important
                                                          A4-3

-------
EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Proprietor
Contact Information


Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
properties that affect pesticide transport and degradation characteristics. The database is
administered by the Alternate Crops & Systems Laboratory in Beltsville, Maryland, which
has the responsibility for adding pesticides and new data as they become available. A
steering committee that represents database users gives advice on the form and content of
the database, (description from website)

Alternate Crops & Systems Laboratory, United States Department of Agriculture

Technical Contact: Don Wauchope
ARS, Southeast Watershed Res. Lab.
don@tifton.cpes.peachnet.edu

CASRN, formula, MW, Physical state, BP, MP, Decomposition point, Heat of vaporization,
Rate Constants-Hydrolysis, Photolysis, VP, Water solubility, Organic solubility, HLC, Kow,
Acid dissociation, Soil sorption, Field dissipation, Soil halflife (aerobic, anaerobic)

This source is considered relevant for the CCL Universe because it contains information on
persistence, that may be used as an indicator of potential occurrence.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.

http://www.ars. usda.gov/Services/docs.htm?docid=14199
Data Source Name
Identification Number
Data Source Description


Proprietor

Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Analytical ABSTRacts (ANABSTR)
ANABSTR contains about 305,000 abstracts covering many sources (i.e., international
journals, books, technical reports, and conference proceedings) of literature on analytical
chemistry. Abstracts date from 1980.

Chemical Abstracts Service; Produced by the Royal Society of Chemistry in England, and
distributed by FIZ CHEMIE of Germany

The Royal Society of Chemistry
Thomas Graham House, Science Park
Milton Road
Cambridge CB4 4WF, UK
Phone: (+44 1)223/432110
Fax:    (+441)223/423623
Email:  stnhlpuk@rsc.org

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.stn-international.de/stndatabases/databases/anabstr.html
Data Source Name


Identification Number
Data Source Description
Aquatic Pollution and Environmental Quality - Cambridge Scientific
Abstracts

7

Because of increasing global concern over the consequences of marine and aquatic
pollution, a separate volume addressing this subject was added to the ASFA series. ASFA 3
is the only abstracts journal devoted exclusively to research and policy on the contamination
 of oceans, seas, lakes, rivers, and estuaries. ASFA 3 contains information that will prove

                      A4-4

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         Identifying the Universe
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Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


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Source URL
essential to specialists who deal in any capacity with aquatic environments and marine
pollution problems, including biologists, oceanographers, limnologists, environmental
engineers and scientists, industrial engineers, waste managers, corporate regulatory affairs
managers, and government officials, (description from website)

Cambridge Scientific Abstracts

Cambridge Scientific Abstracts
7200 Wisconsin Avenue
Bethesda, MD 20814 USA
Voice: 800-843-7751 (in N. America)
Voice: +1 301-961-6700 (worldwide)
Fax:+1 301-961-6720
Email: sales@csa.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.csa.com/csa/factsheets/asfa-3.shtml
Data Source Name

Identification Number
Data Source Description
Proprietor

Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation
AQUatic toxicity Information Retrieval (AQUIRE)

8

AQUIRE is one of three EPA databases that make up the EPA ECOTOXicology (ECOTOX)
database system. AQUIRE, which contains data from national and international scientific
papers on toxicity to aquatic organisms and plants, has over 214,000 aquatic literature
references that cover research from 1970 to the present.

The aquatic data were originally presented in a separate EPA database called AQUIRE
(AQUatic Information  Retrieval). AQUIRE was established in 1981 by the EPA and was
maintained by the Mid-Continent Ecology Division of the National Health and Environmental
Research Laboratory. In 1995, the AQUIRE database became a component of the ECOTOX
database. The aquatic data include freshwater, marine and estuarine exposures to animal and
 plant species. Chemical exposure must be through water, diet, injection or skin; sediment
studies are not included unless a pore (or overlying) water concentration is provided. The
database includes studies dating back to 1915, but the majority of the data encompass test
results reported from 1970 to the present. The aquatic data were used historically for
deriving structure-activity relationship to estimate the toxicity of chemicals lacking toxicity
data and for the derivation of water quality criteria values. To this end, the database has
focused on encoding standard calculated test endpoints, such as the LC50, that can be used
 to compare toxic effects across species, chemicals, and endpoints.  The aquatic component
 does not include dose response information. If a calculated endpoint or statistically
analyzed data were not presented, then the data are ranged into a single effect record.
(description from website)

EPA, Office of Research and Development (ORD), and National Health and Environmental
Effects Research Laboratory (NHEERL), Mid-Continent Ecology Division

ECOTOX Support at T: (218)529-5225 or E-mail: ecotox.support@epa.gov

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.

This source is redundant with ECOTOX (source 57).

This source does not meet retrievability criteria.  This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
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         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Source URL
http://www.epa.gov/med/Prods  Pubs/ecotox.htm
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
ASFA 3: Aquatic Pollution and Environmental Quality - Cambridge
Scientific Abstracts

10

Because of increasing global concern over the consequences of marine and aquatic
pollution, a separate volume addressing this subject was added to the ASFA series. ASFA 3
is the only abstracts journal devoted exclusively to research and policy on the contamination
of oceans, seas, lakes, rivers, and estuaries. ASFA 3 contains information that will prove
essential to specialists who deal in any capacity with aquatic environments and marine
pollution problems,  including biologists, oceanographers, limnologists, environmental
engineers and scientists, industrial engineers, waste managers, corporate regulatory affairs
managers, and government officials, (description from website)

Cambridge Scientific Abstracts

Cambridge Scientific Abstracts
7200 Wisconsin Avenue
Bethesda, MD 20814 USA
Voice: 800-843-7751 (in N. America)
Voice: +1 301-961-6700 (worldwide)
Fax:+1 301-961-6720
Email: sales@csa.com

Bibliographic information,  indexing terms, abstracts, chemical names, and CAS Registry
Numbers
Relevance Explanation


Completeness Explanation

Redundancy Explanation

Retrievability Explanation

Source URL
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is identical to Aquatic Pollution and Environmental Quality - Cambridge Scientific
Abstracts (source 7).

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.csa.com/csa/factsheets/asfa-3.shtml
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Assessment Tools for the Evaluation of Risk (ASTER)

11

ASTER integrates the AQUIRE toxic effects database and a Quantitative Structure Activity
Relationships (QSAR) structure-activity based data system. The database is designed to
provide empirical toxicology data for discrete chemicals where available.  Where discrete
data are not available, the database draws on QSAR-based, mechanistically modeled
predictive estimates for ecotoxicity endpoints, chemical properties, biodegradation, and
environmental partitioning.  The QSAR database contains measured physicochemical
properties for chemicals, including 56,000 molecular structures stored in the Simplified
Molecular Input Line Entry System (SMILES) format.
(description from website)

EPA ORD, NHEERL, Mid-Continent Ecology Division (Duluth,  MN)

Scientific Outreach Program
U.S. Environmental Protection Agency
Office of Research and Development
National Health and Environmental Effects Research Laboratory
Mid-Continent Ecology Division (MED)
6201  Congdon Boulevard
Duluth,  Minnesota 55804
Telephone:  218-529-5225
Fax:        218-529-5003
E-mail: ecotox.support@epa.gov
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Type of Data Elements

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Completeness Explanation
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Source URL
Name, CASRN, SMILES, formula, molecular weight, MP, BP, VP, heat of vaporization, water
solubility, log P, pKa, log Koc, HLC, hydrolysis half life, BOD half life, MacKay level

This source does not meet relevance criteria because it only contains information on
ecological toxicity.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.epa.qov/med/prods  pubs.htm - databases
Data Source Name
Identification Number
Data Source Description
ATSDR CERCLA Priority List

12

The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA)
section 104 (i), as amended by the Superfund Amendments and Reauthorization Act (SARA),
 requires ATSDR and the EPA to prepare a list, in order of priority, of substances that are
most commonly found at facilities on the National Priorities List (NPL) and which are
determined to pose the most significant potential threat to human health due to their known
or suspected toxicity and potential for human exposure at these NPL sites. CERCLA also
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
requires this list to be revised periodically to reflect additional information on hazardous
substances.

This CERCLA priority list is revised and published on a 2-year basis, with a yearly informal
review and revision. Each substance on the CERCLA Priority List of Hazardous Substances
is a candidate to become the subject of a toxicological profile prepared by ATSDR and
subsequently a candidate for the identification of priority data needs. This priority list is
based on an algorithm that utilizes the following three components: frequency of occurrence
at NPL sites, toxicity, and potential for human exposure to the substances found at NPL
sites. This algorithm utilizes data from  ATSDR's HazDat database, which contains
information from ATSDR's public health assessments and health consultations.

It should be noted that this priority list is not a list of "most toxic" substances, but rather a
prioritization of substances based on a combination of their frequency, toxicity, and potential
for human exposure at NPL sites.

Thus, it is possible for substances with low toxicity but high NPL frequency of occurrence
and exposure to be on this priority list. The objective of this priority list is to rank substances
across all NPL hazardous waste sites to provide guidance in selecting which substances will
be the subject of toxicological profiles prepared by ATSDR.  (description from website)

Agency for Toxic Substances and Disease Registry

Agency for Toxic Substances and Disease Registry
Division of Toxicology
1600 Clifton Road NE, Mailstop E-29
Atlanta, GA 30333
Phone: 1-888-422-8737
Fax: 1-404-498-0057
E-mail: ATSDRIC@cdc.gov

Name, CASRN, rank

This source is considered relevant for the CCL Universe because the basis for developing
this list is ATSDR's prioritization of chemicals found at NPL sites and that ATSDR believes
may pose a human health risk.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.atsdr.cdc.gov/cercla/
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         Final CCL 3 Chemicals:
         Identifying the Universe
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Data Source Name

Identification Number
Data Source Description
Proprietor
ATSDR Internet HazDat - Site Contaminant Query

13

According to the HazDat website, HazDat "is the scientific and administrative database
developed to provide access to information on the release of hazardous substances from
Superfund sites or from emergency events and on the effects of hazardous substances on
the health of human populations. The following information is included in HazDat: site
characteristics, activities and site events, contaminants found, contaminant media and
maximum concentration levels, impact on population, community health concerns, ATSDR
public health threat categorization, ATSDR recommendations, environmental fate of
hazardous substances, exposure routes, and physical hazards at the site/event. In addition,
HazDat contains substance-specific information such as the ATSDR Priority List of
Hazardous Substances, health effects by route and duration of exposure, metabolites,
interactions of substances, susceptible populations, and biomarkers of exposure and
effects. HazDat also contains data from the U.S. Environmental Protection Agency (EPA)
Comprehensive Environmental Response, Compensation, and Liability Information System
(CERCLIS) database, including site CERCLIS number, site description, latitude/longitude,
operable units, and additional site information, (description from website)

Agency for Toxic Substances and Disease Registry
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Dr. Sandra Susten, E-mail: sss2@cdc.gov

Maximum concentration, number of states

This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.

http://www.atsdr.cdc.gov/hazdat.html
Data Source Name

Identification Number
Data Source Description
ATSDR Minimal  Risk Levels (MRLs)

123

The ATSDR Minimal Risk Levels (MRLs) were developed as an initial response to
Congressional mandate. Following discussions with scientists within the Department of
Health and Human Services (HHS) and the EPA, ATSDR chose to adopt a practice similar to
that of the EPA's Reference Dose (RfD) and Reference Concentration (RfC) for deriving
substance-specific health guidance levels for non-neoplastic endpoints. An MRL is an
estimate of the daily human exposure to a hazardous substance that is likely to be without
appreciable risk of adverse noncancer health effects over a specified duration of exposure.
These substance-specific estimates,  which are intended to serve as screening levels, are
used by ATSDR  health assessors and other responders to identify contaminants and
potential health effects that may be of concern at hazardous waste sites. It is important to
note that MRLs are not intended to define clean-up or action levels for ATSDR or other
Agencies.

During the development of toxicological profiles, MRLs are derived when ATSDR determines
that reliable and  sufficient data exist to identify the target organ(s) of effect or the most
sensitive health effect(s) for a specific duration for a given route of exposure to the
substance. MRLs are based on noncancer health effects only and are not based on a
consideration of cancer  effects. Inhalation MRLs are exposure concentrations expressed in
units of parts per million (ppm) for gases and volatiles, or milligrams per cubic meter
(mg/m3) for particles. Oral MRLs are expressed as daily human doses in units of milligrams
per kilogram per  day (mg/kg/day). Radiation MRLs are expressed as external exposures in
units of millisieverts.

ATSDR uses the no-observed-adverse-effect-level/uncertainty factor (NOAEL/UF) approach
to derive MRLs for hazardous substances. They are set below levels that, based on current
information, might cause adverse health effects in the people most sensitive to such
substance-induced effects. MRLs are derived for acute (1-14 days), intermediate (>14-364
days), and chronic (365 days and longer) exposure durations, and for the oral and inhalation
routes of exposure. Currently MRLs for the dermal route of exposure are not derived
                                                          A4-8

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         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Proprietor
Contact Information
because ATSDR has not yet identified a method suitable for this route of exposure. MRLs
are generally based on the most sensitive substance-induced end point considered to be of
relevance to humans. ATSDR does not use serious health effects (such as irreparable
damage to the liver or kidneys, or birth defects) as a basis for establishing MRLs. Exposure
to a level above the MRL does not mean that adverse health effects will occur.

Proposed MRLs undergo a rigorous review process. They are reviewed by the Health
Effects/MRL Workgroup within the Division of Toxicology; and expert panel of external peer
reviewers; the agency wide MRL Workgroup, with participation from other federal agencies,
including EPA; and are submitted for public comment through the toxicological profile public
comment period. Each MRL is subject to change as new information becomes available
concomitant with updating the toxicological profile of the substance. MRLs in the most recent
toxicological profiles supersede previously published levels. To date, 120 inhalation MRLs,
189 oral MRLs and 6 external radiation MRLs have been derived, (description from website)

Agency for Toxic Substances and Disease Registry

Dr. Selene Chou
Division of Toxicology
Agency for Toxic Substances and Disease Registry
1600 Clifton Road, Mailstop E29
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
Atlanta, Georgia 30333Telephone: 404-498-0705
E-Mail: cjc3@cdc.gov

Name, CASRN, MRL (chronic, intermediate, acute)

This source is considered relevant for the CCL Universe because it contains data elements
(MRL) derived from toxicological studies.

It meets considerations because it is peer reviewed.

These data are also represented in the ATSDR Toxicological Profiles; however, these data
are tabular while the Profiles are monographic.

This source meets retrievability criteria because it is in tabular format.

http://www.atsdr.cdc.aov/mrls/index.html
Data Source Name

Identification Number
Data Source Description
Proprietor

Contact Information



Type of Data Elements



Relevance Explanation
ATSDR Toxicological  Profiles

210

By Congressional mandate, the Agency for Toxic Substances and Disease Registry
(ATSDR) produces "toxicological profiles" for hazardous substances found at National
Priorities List (NPL) sites. These hazardous substances are ranked based on frequency of
occurrence at NPL sites, toxicity, and potential for human exposure. Toxicological profiles
are developed from a priority list of 275 substances. ATSDR also prepares toxicological
profiles for the Department of Defense (DOD) and the Department of Energy (DOE) on
substances related to federal sites.

So far, 269 toxicological profiles have been published or are under development as "final" or
"drafts for public comment"; 250 profiles were published as finals; 106 profiles have been
updated. Currently, 10 profiles are being revised based on public comments received and
one profile is being developed as a public comment draft.

Note: We have data from Tox Profiles that we downloaded and data from ERG EDPSD.
(description from website)

Agency for Toxic Sutstances and Disease Registry; an agency of the U.S. Department of
Health and Human Services (DHHS), Centers for Disease Control (CDC)

Division of Toxicology, Agency for  Toxic Substances and Disease Registry
1600 Clifton Road, Mailstop E-29, Atlanta, GA 30333
Phone 404-498-0160
Fax 404-498-0094

Name, CASRN, synonyms, trade names, structure, ID numbers, MW, color, physical state,
MP, BP, density, odor, solubility, log Kow, log Koc, VP, HLC, pKa, hydrolysis rate constant,
autoignitiontemp, flashpoint, flammability limits, explosive limits, critical effect, MRLs,
NOAEL, "less serious" and "serious" LOAELs, LDx, LCx, CEL, study-specific data

This source is considered  relevant for the CCL Universe because it contains data elements
                                                          A4-9

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
from toxicological studies and information on production, which may indicate potential

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.atsdr.cdc.aov/toxpro2.html
Data Source Name
AwwaRF Project Reports
Identification Number
Data Source Description
Proprietor

Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
243

Project reports (AWWA)

AwwaRF

Awwa Research Foundation
6666 W. Quincy Avenue
Denver, Colorado 80235-3098 USA
Email: info@awwarf.org
Telephone: 303.347.6100
Fax: 303.730.0851

Name, Concentrations (|jg/L, mg/L), # Utilities that participated in the project, # States that
detected contaminant

This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http://www.awwarf.org
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation
Bad Bug Book

14

This database of fact sheets contains basic information on foodborne pathogenic
microorganisms and natural toxins. It incorporates information from the U.S. Food & Drug
Administration (FDA), CDC, USDA Food Safety Inspection Service, and the National
Institutes of Health (NIH). Pathogens covered include over 40 bacteria, viruses, parasites,
and natural toxins. While not intended to be comprehensive, basic information includes
characteristics, habitat or source, associated foods, infective dose, characteristic disease
symptoms, complications, recent and/or major outbreaks, and any susceptible populations.
(description from website)

FDA - Center for Food Safety and Applied Nutrition

FDA
Center for Food Safety and Applied Nutrition
Outreach and Information Center
5100 Paint Branch Parkway HFS-555
College Park, MD 20740-3835
Toll-Free Information Line:

1-888-SAFEFOOD
(1-888-723-3366)

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet  relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
                     A4-10

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         Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
inconsistently presented.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is one of the sources administered by CSFAN (source 231).
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://vm.cfsan.fda.aov/~mow/intro.html
Data Source Name
Identification Number
Data Source Description

Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Base de Dados Tropical (BDT)
15
BDT is a searchable database of biological organisms cataloged in Brazilian laboratories,
including viruses, bacteria, and protozoa.  The database lists laboratories that maintain
strains, and contact information for those laboratories.
Andre Tosello Foundation (a Brazilian NGO)
BDT - Base de Dados Tropical
Rua Latino Coelho, 1301
13087-010 Campinas SP
phone: (19) 3242-7022
fax: (19)3242-7022
Laboratories that maintain strains, contact information for those laboratories
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.bdt.fat.org.br/index
Data Source Name
Identification Number
Data Source Description

Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Sergey's Manual of Systematic Bacteriology
16
This manual is intended as a guide for treatments and ecological information on identified
bacteria, organized along phylogenetic lines. The website also contains links to many other
databases and resources.
Michigan State University; Sergey's Manual Trust
Denise Searles
searles@pilot.msu.edu
Sergey's Manual Trust
Department of Microbiology and Molecular Genetics
Michigan State University
East Lansing, Michigan 48824-1101
(517)432-2457
(517) 432-2458 (fax)
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
Completeness Explanation      It meets considerations because it is peer reviewed.
Redundancy Explanation
Retrievability Explanation
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
                      A4-11

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         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Source URL
http://www.cme.msu.edu/berqevs/
Data Source Name
Identification Number
Data Source Description
Biennial Reporting System

272

BRS is a national level system of data collection on the generation, management, and
minimization of hazardous wastes. BRS captures detailed data on the generation of
hazardous waste from large quantity generators and data on the waste management
practices from treatement, storage and disposal facilities in the United States. These data
are collected every other year and provide the ability to perform trend analyses.
                                   SUBJECT COVERAGE :
Proprietor
Contact Information
Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Facility Location and Identification Data
Handler Classification & Contact Information
Waste Code and Information
 Off-Site and On-Site Management Information
User Comments on Generated and Reported Waste
Description of Reported Waste
(description from website)

National Information Services Corporation (NISC)

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Facility Location and Identification Data, Handler Classification & Contact Information,
Waste Code and Information, Off-Site and On-Site Management Information, User
Comments on Generated and Reported Waste, Description of Reported Waste

This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.nisc.com/cis/details/brs.htm
Data Source Name
Identification Number
Data Source Description
BIOBUSINESS Biological Abstracts Database

17

BioBusiness® provides current and retrospective information to business executives,
financial analysts, product development and marketing professionals, and information
specialists about the business applications of biological and biomedical research. The
database covers the economic aspects of all life sciences areas. Five hundred technical and
 business journals, magazines, newsletters, meeting proceedings, U.S patents, and books
from all over the world were scanned for relevant articles. BioBusiness is no longer being
updated. More than 1,100 technical and business journals, magazines, newsletters, meetings
Proprietor
Contact Information
proceedings, and books from around the world are scanned for articles relevant to the
subject coverage of the file, (description from website)

Thomson Dialog

BIOSIS
User Communications Group
2100 Arch Street
Philadelphia, PA 19103-1399
                      A4-12

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         Final CCL 3 Chemicals:
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Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Telephone: 215-587-4847 (Worldwide)
800 Line: 800-523-4806 (U.S. except AK, HI, PA)
Fax:215-587-2016
E-Mail: info@mail.biosis.org

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://librarv.dialoa.com/bluesheets/html/bl0285.html
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Biological Sciences - Cambridge Scientific Abstracts

18

This interdisciplinary database offers abstracts and citations to a wide range of research in
biomedicine, biotechnology, zoology and ecology, and some aspects of agriculture and
veterinary science. Supporting over two dozen areas of expertise, this CSA database
provides access to literature from over 6000 serials, as well as conference proceedings,
technical reports, monographs and selected books and patents,  (description from website)

Cambridge Scientific Abstracts

Cambridge Scientific Abstracts
7200 Wisconsin Avenue
Bethesda, MD 20814 USA
Voice: 800-843-7751 (in N. America)
Voice: +1 301-961-6700 (worldwide)
Fax:+1 301-961-6720
Email: sales@csa.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text  (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
Source URL
http://www.csa.com/csa/ids/databases-collections.shtml -environmental
Data Source Name

Identification Number
Data Source Description
Proprietor
BIOSIS Biological Abstracts and BIOSIS Previews

19

BIOSIS Biological Abstracts is "the most comprehensive collection of bibliographic
references to life science journal literature published internationally."  BIOSIS Previews is a
bibliographic database including international literature sources on biological and biomedical
topics. The BIOSIS sources have nearly 13 million bibliographic records available, compiled
from 5,000 or more scientific journals, technical reports, meetings, reviews, books,
monographs, and file data, from  1969 to the present.  Relevant subject coverage includes
biochemistry, biophysics, environmental biology, microbiology, pathology, pharmacology,
and toxicology, (description from website)
BIOSIS
                                                        A4-13

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Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Thomson
3501 Market Street
Philadelphia, PA 19104 USA
phone: 1-800-336-4474 (USA and Canada)
215-386-0100 (Worldwide)
fax:215-243-2208
e-mail: info@biosis.org

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.biosis.org/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information

Type of Data Elements
Relevance Explanation
Bugs

20

The Bugs program was designed to help medical students learn basic microbiology and
pathogenesis in a clinical context. It is based on the Bugs database, containing information
on 159 pathogens - the diseases they cause, the signs and symptoms of the diseases, the
source of the organism, sites where it is normal and sites where it is pathogenic, virulence
mechanisms, diagnostic factors, treatment, and prevention,  (description from website)

University of Florida College of Medicine

For information on using this program contact Donna Duckworth Phd.
duckwort@mgm.ufl.edu

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
Completeness Explanation      It meets considerations because it meets all NDWAC minimum data requirements.
Redundancy Explanation
Retrievability Explanation
Source URL
This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://medinfo.ufl.edu/vear2/mmid/bms5300/bugs/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
CAB Abstracts - CABI Publishing

21

CAB Abstracts is CABI Publishing's main database, for the applied life sciences. It covers
research and development literature in the fields of agriculture, forestry, aspects of human
health, human  nutrition, animal health and the management and conservation of natural
resources.

CAB Abstracts contains over 4 million records from 1973 to present, with over 180,000 new
records added  each year. CAB Abstracts is available through a variety of third party
vendors, including Ovid, ISI, EBSCO,  Dialog, DIMDI, STN, BIDS and CAB Direct.
(description from website)

CABI Publishing

CABI Publishing North America
875 Massachusetts Avenue,
                                                        A4-14

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Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
7th Floor, Cambridge,
MA 02139,  USA
Email: cabi-nao@cabi.org
Tel:+1 6173954056
Toll free: +1 800 528 4841
Fax:+1 6173546875

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated  retrieval.

http://www.cabi-publishina.org/Products/Database/Abstracts/lndex.asp
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
California Department of Pesticide Regulation (CDPR)

235

State monitoring program list and links to reports (AWWA)

List of registered active ingredients and product counts.
http://www.cdpr.ca.gov/docs/label/actai.htm

California Department of Pesticide Regulation

John Stutz
Phone:(916)324-3906
email: jstutz@cdpr.ca.gov
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Name, number of products used in

This source is considered relevant for the CCL Universe because it contains a list of
bioactive compounds.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.

http://www.cdpr.ca.gov/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
CANCERLIT

22

CANCERLIT is a bibliographic database including source information from biomedical
journals, proceedings, books, reports, and doctoral theses.  The database contains over 1.5
million citations and includes references to cancer literature published from the 1960s to the
present. The database is focused on biomedical aspects of cancer literature,  (description
from website)

National Cancer Institute; a component of NIH, within the DHHS

NCI Public Inquiries Office
Suite 3036A
6116 Executive Boulevard, MSC8322
Bethesda, MD 20892-8322
1-800-4-CANCER (1-800-422-6237)

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry

                     A4-15

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         Final CCL 3 Chemicals:
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EPA815-R-09-006
      August 2009
Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.cancer.gov/cancerinfo/literature
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information


Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Carcinogenic Potency Project (CPP)

23

The Carcinogenic Potency Database (CPDB) is a systematic and unifying analysis of
animal cancer tests. It standardizes the published literature and creates an easily accessible
research resource that can be and has been used to address a wide variety of research and
regulatory issues in carcinogenesis. A measure of carcinogenic potency, TD50 (tumorigenic
dose-rate for 50% of experimental animals), is estimated for the tumor incidence at each site
for which results are reported in the database. The CPDB includes results reported in 1383
papers in the general literature through 1996 and 421 Technical Reports of the National
Cancer Institute/National Toxicology Program (NCI/NTP) through 1998. Results are
examined for 6008 experiments on 1451 chemical agents; these are displayed in a plot
format organized by chemical name. Detailed information that is important in the
interpretation of bioassays, is reported on each experiment, (whether positive or negative for
carcinogenicity) including: qualitative information on strain, sex, target organ, histopathology
and author's opinion, as well as quantitative information on carcinogenic potency, statistical
significance, tumor incidence, dose-response curve shape, length of experiment, dose-rate,


and duration of dosing. Each set of experimental results references the original published
paper. A word of caution is necessary about the limitations of the database. No attempt  has
been made to evaluate whether or not a compound induced tumors in any given experiment;
rather, the opinion of the published authors is presented as well as the statistical significance
of the TD50 calculated from their results. Moreover, the database contains only long-term
tests which fit a set of criteria designed to measure potency, and therefore does not cover
all cancer tests. (From the CCP's website: http://potency.berkeley.edu/text/methods.html)

Lawrence Berkeley Laboratory

Carcinogenic Potency Database
Mail Stop: 946
1  Cyclotron Road

Name, CASRN, administered dose, TD50 (tumorigenic dose), tumor type, 99% Cl on TD50

This source is considered relevant for the CCL Universe because it contains data on
carcinogenicity from toxicological studies.

It meets considerations because it is peer reviewed.

This source is redundant with DSSTox (source 53).

This source meets retrievability criteria because it is in tabular format.

http://potencv.berkelev.edu/cpdb.html
Data Source Name

Identification Number
Data Source Description
Case/M Case/M C4PC

238

The MCASE program will accept the structure of a series of diverse compounds and their
observed activity (quantitative or qualitative) in a biological test performed under a common
protocol. The program will automatically evaluate the data set and try to identify the
structural features responsible for activity (biophores). It then creates organized dictionaries
of these biophores and develops ad hoc local QSAR correlations that can be used to predict
the activity of unknown molecules.

                      A4-16

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Proprietor
Contact Information
Upon entering a new molecule, the MCASE program will evaluate it against the dictionary and
the appropriate QSARs it has created and, based on the results, venture a prediction as to
the projected activity of the molecule in the corresponding test. All conclusions can be
documented and rationalized by querying the program. If the activity of the molecule is
known, its observed value will also be displayed.

This program is particularly useful in drug design, when the user intends to analyze
proprietary information and create its own dictionaries. It  can also accept the databases
offered in conjunction with the CASETOX program,  (description from website)

Multicase

Prof. Gilles Klopman, President & CEO

e-mail: klopman@multicase.com
Phone:(216)831-3740
fax:(216)831-3742

Mailing Address:

MULTICASE Inc.
23811 Chagrin Blvd. Ste 305
Beachwood, OH44122
Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Unknown

This source is considered relevant for the CCL Universe because it could be a source of
information on potential health effects.

It does not meet considerations because no information on type of data elements is
available.

This source is not redundant.

This source does not meet retrievability criteria.  The source does not contain data; it is a
model that might be used to generate estimates. The source is only available through a

http://www.multicase.com/products/prod01.htm
Data Source Name

Identification Number
Data Source Description
Center for Food Safety and Applied Nutrition (CFSAN)

231

CFSAN, in conjunction with the Agency's field staff, is responsible for promoting and
protecting the public's health by ensuring that the nation's food supply is safe, sanitary,
wholesome, and honestly labeled, and that cosmetic products are safe and properly labeled.
                                    The Center's primary responsibilities include:
                                    - the safety of substances added to food, e.g., food additives (including ionizing radiation)
                                    and color additives
                                    - the safety of foods and ingredients developed through biotechnology
                                    - seafood Hazard Analysis and Critical Control Point (HACCP) regulations
                                    - regulatory and research programs to address health risks associated with foodborne
                                    chemical, and biological contaminants
                                    - regulations and activities dealing with the proper labeling of foods (e.g., ingredients,
                                    nutrition health claims) and cosmetics
                                    - regulations and policy governing the safety of dietary supplements, infant formulas, and
                                    medical foods
                                    - safe and properly labeled cosmetic ingredients and products
                                    - food industry postmarket surveillance and compliance
                                    - consumer education and industry outreach
                                    - cooperative programs with state and local governments
                                    - international food standard and safety harmonization efforts

                                    Some of CFSAN's current areas of food safety concern are:
                                    - biological pathogens
                                    - naturally occurring toxins
                                    - dietary supplements
                                    - pesticide residues
                                                          A4-17

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      August 2009
Proprietor
Contact Information
Type of Data Elements
- toxic metals
- decomposition and filth
- food allergens
- nutrient concerns
- dietary components
- radionuclides
- TSE-type diseases
- product tampering
(description from website)

FDA - Center for Food Safety and Applied Nutrition

FDA
Center for Food Safety and Applied Nutrition
Outreach and Information Center
5100 Paint Branch Parkway HFS-555
College Park, MD 20740-3835
1-888-SAFEFOOD (1-888-723-3366)

Data elements for microbial contaminants, food additives, and contaminants that are found
in food
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://vm.cfsan.fda.gov
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Chemfinder

29

Chemfinder is a chemical database that also incorporates a web search for locating chemical
 information such as CAS registry numbers, molecular formulas and structures, and some
physical property information.  It also provides a list of indexed web sites on chemical
information in categories like health, biochemistry, and physical properties during a search
for information on any given chemical,  (description from website)

CambridgeSoft Corporation

CambridgeSoft Corporation
100 CambridgePark Drive
Cambridge, MA 02140 USA
Tel  1 800 315-7300 /1 617 588-9300
Fax 1 617588-9390
email: info@chemfinder.com

Name, Synonyms,Formula, CAS RN, Water Solubility, Links to other websites with
information about the compound  in the categories: Biochemistry, Physical  Properties,
Usage, Health, Regulations, Misc, MSDS, Structures, Pesticides/Herbicides, Trading

This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.

It meets considerations because  it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.

http://chemfinder.cambridgesoft.com/
                                                        A4-18

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      August 2009
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Chemical Backgrounder

30

The U.S. National Safety Council (NSC) publishes a series of Chemical Backgrounders,
which contain data on over 80 regulated chemicals.  The Chemical Backgrounders give a
brief synopsis of physicochemical properties, usage, manufacturers, regulations, and health
effects, (description from website)

National Safety Council

National Safety Council
1121 Spring Lake Drive
Itasca, IL 60143-3201
(630)285-1121
(630) 285-1315 fax
info@nsc.org
Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation

Retrievability Explanation

Source URL
Description, Chemical and physical properties, Identification, Health effects, Exposure
Values, Economics, Regulation, National Overview of 1998 Toxics Release Inventory

This source is considered relevant for the CCL Universe because it contains inhalation
exposure limits, which may provide information on potential health effects.

It does not  meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated  retrieval.

http://www.nsc.ora/librarv/chemical/chemical.htm
Data Source Name
Identification Number

Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Chemical Carcinogenesis Research Information System (CCRIS)

24

CCRIS is a toxicology data file of the National Library of Medicine's (NLM) Toxicology Data
Network (TOXNET®). It is a scientifically evaluated and fully referenced data bank,
developed and maintained by the National Cancer Institute (NCI). It contains over 8000
chemical records with carcinogenicity, mutagenicity, tumor promotion, and tumor inhibition
test results. Data are derived from studies cited in primary journals, current awareness tools,
 NCI reports, and other special sources. Test results have been reviewed by experts in
carcinogenesis and mutagenesis.  A useful feature  is that searching for one substance will
produce information for other substances which are relevant. For example, a search for
acetone will bring up isopropanol, because acetone is one of its metabolites, (description
from website)

National  Library of Medicine; NIH; developed and maintained by NCI

CCRIS Representative
Specialized Information Services
National  Library of Medicine
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Telephone (30!) 496-1131
FAX: (301) 480-3537
e-mail: toxmail@toxnetmail.nlm.nih.gov
URL: http://sis.nlm.nih.gov

Major Use, Administrative Information, Mutagenicity Study, Carcinogenicity Study,
Tumor Promotion, Tumor Inhibition

This source is considered relevant for the CCL Universe because it contains the results of
carcinogenicity and mutagenicity studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
                      A4-19

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         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Source URL
http://toxnet.nlm.nih.gov/cai-bin/sis/htmlaen7CCRIS
Data Source Name
Identification Number
Chemical Evaluation Search  and Retrieval (CESARS) - CCOHS
28
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
The CESARS database contains information on chemicals, including health effects in
humans, mammals, and aquatic and plant life; also covers data on physicochemical
properties, and environmental fate and transport. Includes a total of 850 chemical profiles,
each containing data on up to 23 topic areas drawn from authoritative reviews focusing on
toxicological and environmental investigations into toxicity, transformation processes,
bioaccumulation, bioconcentration, transport carcinogenicity, mutagenicity, and reproductive
toxicity. (description from website)

Canadian Center for Occupational Health and Safety (CCOHS)

clientservices@ccohs.ca
1-800-668-4284 (Canada and USA)
1-905-570-8094
1-905-572-2206 (FAX)

Properties- Physical and Chemical: Molecular formula, molecular weight, physical state,
melting point, boiling point, flash point, autoignition point, explosive limits, density, specific
gravity, Henry's law constant, pKa, TOD, BOD, COD, conversion factor, odor threshold air,
water and taste, aqueous solubility, vapor pressure, and n-octanol/water partition coefficient.
 Regulations and Guidelines: US, Canadian and International  data pertaining to acceptable
levels in the environment, waste disposal requirements, health and safety guidelines,
labelling and transportation is included.  Manufacture: Uses, occurrence, production and
methods of synthesis.  Acute Toxicity - Terrestrial animals/ Human/ Aquatic animals:
Adverse effects such as LD50 or LC50 for test exposures to animals, adverse effects to
humans by test compounds; toxicity studies on freshwater aquatic species such as LC50 or
EC50; all undertaken in short term tests. Chronic Toxicity - Terrestrial animals/ Humans/
Aquatic animals: Toxicity studies undertaken in medium to long term time frames, such as
NOAELs (No Observed Adverse  Effect Levels),  MATC (Maximum Adverse Toxicant
Concentration), etc. Phytotoxicity: Information on effects of substances to aquatic and
terrestrial plants. Carcinogenicity: Summaries of studies conducted by NCI/NTP,  IARC,
NIOSH, EPA. Mutagenicity: Effects are reported such as gene mutations, chromosomal
aberrations and DMA damage. Reproductive and Developmental Effects: Reports of
chemical effects on terrestrial animals or humans are reported. NOAELs may be  provided if
available. Other Adverse Effects: Other effects which may be reported such as aesthetic
effects. Pharmacokinetics/Metabolism: Uptake, distribution, biotransformation and
elimination in animals.  Bioaccumulation/Bioconcentration: Bio-uptake of chemicals in aquatic
organisms. Transport Processes: Transport of chemicals in the environment including
sorption to matter in water, air, soil, sediment or biota (flora and fauna) and volatilization
from water or soil.
General Fate Processes: Reports on studies predicting the fate of chemicals in the
environment. Transformation Processes: Biodegradation by microorganisms and hydrolysis
of compounds. Analysis and Treatment: Standard analytical techniques plus water or waste
treatment methods, if available.
References: Ontario Environmental Assessment: The Ontario Ministry of the Environment
assessment and scoring of the chemical.

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because  it is peer reviewed.

This source is not redundant.

This source does  not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http ://www. ccohs. ca/prod ucts/databases/cesars. htm I
                                                          A4-20

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Data Source Name
Identification Number
Data Source Description
Chemical Hazard Response Information System

285

CHRIS provides information needed to respond to emergencies that occur during the
transport of hazardous chemicals. It also provides information that can be used to design
safety procedures aimed at preventing emergency situations. While geared toward
chemicals transported over water, this information can be useful for a wide range of
chemical emergency situations.

SUBJECT COVERAGE :
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Chemical/Physical Property Data
Health and Fire Hazard Data
Hazard Classification Data
Labeling Information
Reactivity Data
Water Pollution Data
(description from website)

National Information Services Corporation (NISC)

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797  Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Chemical/Physical Property Data, Health and Fire Hazard Data, Hazard Classification Data,
Labeling Information, Reactivity Data, Water Pollution Data

This source does  not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does  not meet retrievability criteria because it is only available through a
subscription.

http://www.nisc.com/cis/details/chris.htm
Data Source Name
Identification Number
Data Source Description

Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Chemical Information System (CIS) - ILO/OSHIC

36

Database is no longer available through INCHEM. Does not appear to be available through
ILO web site.

International Labour Organisation Occupational Safety and Health Information Centre

N/A

Not applicable

This source is no longer available online.

This source is no longer available online.

This source is no longer available online.

This source is no longer available online.

http://www.inchem.ora/pages/ilodb.html
                                                      A4-21

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Data Source Name
Identification Number
Chemical Registry System (CRS)
42
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation
Source URL
CRS is part of a single meta-data registry of EPA information sources, and provides
information on 70,161 chemical substances, including representation in EPA regulations as
well as data systems. Results of a search may also include links to other information
sources on the chemical database.  Ninety-three sources are checked from 23 submitting
organizations. Substance files include the following sections: chemical synonyms, a list of
regulations applicable to the chemical and other regulatory information, health effects
sources for the queried chemical, and information about the general group of chemicals.
(description from website)

EPA, Office of Environmental Information

Michael Pendleton
United States Environmental Protection Agency
Office of Environmental Information
1200 Pennsylvania Avenue, NW
Mail Code 2822-T
Washington, DC 20460
pendleton.michael@epa.gov
Phone:(202)566-1658
Fax:(202)566-1639

CAS RN, Classification, Molecular Formula, Molecular Weight, Regulatory Resources
Other Sources, Group/Component,  Related Links

This source is considered relevant for the CCL Universe because it is an interface to other
information in EPA's SRS system.

It meets considerations because it is peer reviewed.

This source is redundant, as it is wholly available as part of Substance Registry System
(SRS) (source 203).

This source meets retrievability criteria because it is in tabular format.

http://www.epa.gov/srs/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Chemical Toxicity Database - Ministry of Health and Welfare, Japan

31

Japan has been studying chemical toxicity under the initiative of the National Institute of
Health Sciences and has also been performing safety tests of existing chemicals with high
production volume (HPV) in cooperation with the U.S., the EC, and other OECD member
countries as one of the OECD Chemicals programme Group members since 1991. These
data being generated are very important to ensure chemical safety. Furthermore common
utilization of the data among the member countries facilitates global enforcement of safety
programmes.

Toxicity studies conducted for individual environmental chemicals include a single dose
toxicity test,  a 28-day repeat dose toxicity test, a reproductive/development toxicity test
and mutagenicity tests. Each test has various practical and academic contents such as
animal species, dose, test method and types of toxicity appearance. The results are
intended for publication as academic report documents.
(description from website)

Ministry of Health and Welfare, Japan

Ministry of Health,  Labor, and Welfare
1-2-2 Kasumigaseki Chiyoda-ku Tokyo
100-8916 Japan
03-5253-1111
www-admin@mhlw.go.jp

Name, CASRN, formula, LD50, NOEL, mutation data
Relevance Explanation
This source is considered relevant for the CCL Universe because it contains data elements
(LD50, NOEL) from toxicological studies.
                                                        A4-22

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        Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because the relevant data can be extracted in tabular
format.

http://dra4.nihs.go.ip/mhlw data/isp/ListPageENG.isp
Data Source Name
Identification Number
Data Source Description
Chemical Update System (CDS)
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
32

"The Chemical Update System (CUS) contains confidential data reported by industry
(approximately 1200 companies) as a partial update of the Toxic Substances Control Act
(TSCA) Inventory.  Manufacturers and importers are required to report company information
(plant site name, address, Data Universal Numbering System (DUNS) number) and chemical
 information (CAS registry number, Premanufactures Number (PMN)/Bonafide/Test
Marketing Exemption Application (TMEA) or Confidential Chemicals Identification (CCID)
System Assession Number, and production volume) for chemicals they manufactured or
imported in excess of 10,000 pounds in the immediately preceding fiscal year." (description
from website)

EPA OPPT

Office of Prevention, Pesticides, and Toxic Substances,  Pollution Prevention and Toxics,
Records and Dockets Management Branch

Contact: Darryl Ballard
Mail Code: 7407
Telephone: 202-564-8958

Production Volume

This source is considered relevant for the CCL Universe because it contains information on
production volume, which may indicate potential  occurrence.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is redundant with CUS/IUR (source 33).

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval. This source is retrievable through CUS/IUR.

http://www.epa.gov/records/policv/schedule/sched/273.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Chemical Update System/Inventory Update Rule (CUS/IUR)

33

"The Chemical Update System (CUS) contains confidential data reported by industry
(approximately 1200 companies) as a partial update of the Toxic Substances Control Act
(TSCA) Inventory.  Manufacturers and importers are required to report company information
(plant site name, address, Data Universal Numbering System (DUNS) number) and chemical
 information (CAS registry number, Premanufactures Number (PMN)/Bonafide/Test
Marketing Exemption Application (TMEA) or Confidential Chemicals Identification (CCID)
System Assession Number, and production volume) for chemicals they manufactured or
imported in excess of 10,000 pounds in the immediately preceding fiscal year." (description
from website)

EPA
Contact Information
Type of Data Elements
Relevance Explanation
Darryl Ballard
RDMB
202-564-8958
ballard.daryll@epa.gov

Production Volume

This source is considered relevant for the CCL Universe because it contains information on

                     A4-23

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Completeness Explanation
Redundancy Explanation

Retrievability Explanation
Source URL
production volume, which may indicate potential occurrence.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.epa.gov/iur/
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Chemicals in Commerce Information System (CICIS) - Toxic
Substances Control Act Inventory

283

The Toxic Substances Control Act (TSCA) of 1976 requires the Environmental Protection
Agency (EPA) to maintain a list of chemical substances that have been manufactured,
imported, or processed in the United States for commercial purposes since January 1, 1975.
The TSCAINV database contains this list and is commonly referred to as the TSCA
Inventory. Note that the database contains only the public portion of the Inventory; a
supplemental, "confidential" portion of the Inventory is maintained by EPA.

SUBJECT COVERAGE :
CAS Registry Number
Chemical Name Identification
TSCA Status
(description from website)

National Information Services Corporation (NISC)/EPA

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Name, CASRN, TSCA Status

This source is considered relevant for the CCL Universe because it is a list of chemicals in
production.

It meets considerations because it meets all NDWAC minimum data requirements.

The source is redundant with TSCA.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.nisc.com/cis/details/tscainv.htm
Data Source Name
ChemlDplus - Chemical Identification Plus
Identification Number
Data Source Description
34

ChemlDplus contains one record per chemical substance for over 368,000 compounds cited
in the National Library of Medicine (NLM) databases residing on either the ELHILL® or the
TOXNET® system. The data elements include: CAS registry numbers, molecular formulas,
systematic names, synonyms, MeSH® headings, name and formula fragments, and list and
file locator designations. Along with that information,  ChemlDplus lists many links to
information in other databases for a chemical, including all NLM databases and many others:
CCRIS, Developmental and Reproductive Toxicology / Environmental Teratology
Information Center (DART/ETIC), Gene-Tox, Hazardous Substances Data Bank (HSDB)
Structures, Integrated Risk Information System (IRIS), NCI-3D, Toxline, and the Toxics
Release Inventory (TRI). ChemlDplus contains molecular structures for 206,098 of the
chemicals in the database.

ChemlDplus is searchable by Name, Synonym, CAS Registry Number, Molecular Formula,

                     A4-24

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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Classification Code, Locator Code, and Structure, (description from website)

National Library of Medicine; Division of Specialized Information Services, NIH

Specialized Information Services
National Library of Medicine
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Fax:(301)480-3537
Telephone: (301) 496-1131
e-mail: tehip@teh.nlm.nih.gov

Name, CASRN, molecular formula, database listings

This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.

http://chem.sis.nlm.nih.gov/chemidplus/
Data Source Name

Identification Number
Data Source Description
Proprietor

Contact Information
Clinical Virology

37

New edition of a reference that informs scientists and health care professionals about the
medically relevant aspects of this rapidly evolving field. The 56 contributions by experts in
their respective specialties, incorporating the latest developments and relevant citations to
address infections and syndromes related to particular organ systems; the fundamentals of
modern medical virology including immune responses and vaccinology, diagnostics,
antivirals, and gene therapy; and the virology, epidemiology, pathogenesis, clinical
manifestations, laboratory diagnosis, and prevention and treatment of important specific
human viral pathogens. Edited by Richman (pathology and medicine, U. of California),
Richard J. Whitley (infectious diseases, U. of Alabama) and Frederick G. Hayden (internal
medicine  and pathology, U. of Virginia School of Medicine).

Book News, Inc.®, Portland, OR

(description from Amazon.com)

Richman, Whitely, Hayden, editors. 2002.  Churchill Livingstone, publishers

Douglas D. Richman, MD
VA San Diego Healthcare System
University of California San Diego
Departments of Path & Med, 0679
                                   9500 Oilman Drive
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

Error! Hyperlink reference not valid.
                                                          A4-25

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EPA815-R-09-006
      August 2009
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Communicable Disease Report (CDR) - United Kingdom

25

The CDR Weekly is an electronic bulletin that is published each Thursday. It has been
electronic since 2001, and was published as an open circulation bulletin from 1991 onwards.
It comprises a weekly section of public health news and other pages of routine
microbiological and epidemiological data and reports, which are updated on a monthly basis
(ie, reports by Infections). They include: Enteric, Respiratory, Immunisation, HIV and STIs,
Bacteraemia, Zoonoses, Travel Health, Primary Care.  Each section has a comprehensive
archive of all relevant articles and data published in the current year. PDF files of back
copies are available from 1991  onwards on the back issues page, (description from website)

U.K. Health Protection Agency

Communicable Disease Report Weekly
Information Knowledge Management Dept.
61 Colindale Avenue
London, NW9 5DF
United Kingdom
Telephone +44 (0)20 8200 1295
Fax+44 (0)20 8358 3130
email: neil.hough@hpa.org.uk

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It does not meet considerations because there was no  documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.hpa.org.uk/cdr/default.htm
Data Source Name
Communicable Disease Reports (CDR) - Australia
Identification Number
Data Source Description
Proprietor
245

The Surveillance and Epidemiology Section of the Population Health Division (PHD) is the
Commonwealth's primary data collection and coordination centre for many communicable
diseases. The PHD also coordinates and contracts other agencies to collect data and/or
conduct research on communicable diseases. Two such centres are the National Centre in
HIV Epidemiology and Clinical Research (NCHECR) and the National Centre for
Immunisation Research and Surveillance of Vaccine Preventable  Diseases (NCIRS).

National surveillance networks and centres facilitate early detection of disease as well as
long-term epidemiological analysis. These in turn provide essential information for planning
interventions, and form the foundation for future public health priorities and clearly focused
evidence-based policy development and best practice. This philosophy is reflected in work
carried out or co-ordinated through the PHD. As part of the National Communicable Diseases
 Surveillance Strategy, States/Territories and the Commonwealth  are improving  current
surveillance systems to build the capacity and infrastructure for future nationally consistent
surveillance systems which will deliver more comprehensive data  for all communicable
diseases of public health significance.

Surveillance data is disseminated through the quarterly publication Communicable Diseases
Intelligence (GDI). GDI publishes occasional reports on some national surveillance schemes,
 including the National Mycobacterial Surveillance System, the Australian Mycobacterial
Reference Laboratory Network, the National Neisseria Network, OzFoodNet, Rotavirus
surveillance and the Sentinel Chicken Scheme. Information on national surveillance schemes
 routinely  reported in GDI are detailed  in the document Surveillance systems reported in
GDI. (description from website)

Australian Government
                                                         A4-26

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Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Communicable Diseases Intelligence
Surveillance and Epidemiology Section
Population Health Division
MDP14
PO Box 9848
Canberra ACT, 2601
Telephone: +61 2 6289 8245
Facsimile: +61 2 6289 7791

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.health.aov.au/pubhlth/strateg/communic/index.htm
Data Source Name

Identification Number
Data Source Description
Compendium of Pesticide Common Names
For purposes of trade, registration and legislation, and for use in popular and scientific
publications, pesticides need names that are short, distinctive, non-proprietary and widely-
accepted. Systematic chemical names are rarely short and are not convenient for general
use, and so standards bodies assign common names to the active ingredients of pesticides.
More than 1000 of these official pesticide  names have been assigned by the International
Organization for Standardization (ISO).

This Compendium is believed to be the only place where all of the ISO-approved standard
names of chemical pesticides are listed. It also includes approved names from national and
Proprietor
Contact Information
Type of Data Elements

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
international bodies for pesticides that do not have ISO names, (description from website)

Alan Wood (http://www.hclrss.demon.co.uk/demos/alan_wood.html)

Alan Wood
Context Limited
Grand Union House
20 Kentish Town Road
London
NW1  9NR
United Kingdom
Telephone: 020 7267 8989

Name (common, IUPAC), CASRN, molecular formula, structure

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source meets retrievability criteria because it is in HTML format and can be extracted in
tabular form at.

http://www.hclrss.demon.co.uk/
Data Source Name
Comprehensive Environmental Response, Compensation, and
Liability Information System (CERCLIS)
                                                      A4-27

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Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
38

This database allows a user to access administrative and geographic information about all
Superfund sites around the country.  Users can access maps for each facility, which
display sites of discharges to water, hazardous waste containment, and toxic/air releases, as
well as site assessment and remediation information, (description from website)

EPA Envirofacts Data Warehouse and Applications

enviromail@epamail.epa.gov

Facility Information, Site Name, Address, County, Site SMSA, Federal Facility, NPL Status,
Corporate, Mapping Info, Record of Decision (ROD) Info, EPA Regional, Latitude, Longitude,
Ownership,  Site, Incident, Action, Responsibility, Planned Outcome, Urgency

This source is considered relevant for the CCL Universe because it contains information on
potential contaminant occurrence at superfund sites.

It meets considerations because it is peer reviewed.

This source is not redundant.

Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.

http://www.epa.aov/enviro/html/cerclis/cerclis  auerv.html
Data Source Name
Identification Number
Computer Retrieval  of Information on Scientific Projects
276
Data Source Description
CRISP is a searchable database of federally funded biomedical research projects conducted
at universities, hospitals, and other research institutions. The database, maintained by the
Office of Extramural Research at the National Institutes of Health (NIH), includes projects
funded by NIH, Substance Abuse and Mental Health Services Administration (SAMHSA),
Health Resources and Services Administration (HRSA), Food and Drug Administration
(FDA), Centers for Disease Control and Prevention (CDC), Agency for Healthcare Research
and Quality (AHRQ), and Office of Assistant Secretary of Health (OASH). Users can
search for scientific concepts, emerging trends and techniques, or identify specific projects
and/or investigators. The database currently includes records from between 1992 and 2000.
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation
SUBJECT COVERAGE :

Project Title and Abstract
Indexing Terminology
 Name(s) of Investigator(s)
Sponsoring Institution(s)

(description from website)

National Information Services Corporation (NISC)

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.
                                                        A4-28

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Retrievability Explanation

Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.nisc.com/cis/details/crisp.htm
Data Source Name

Identification Number
Data Source Description
Proprietor
Concise International Chemical Assessment Documents (CICADs)

35

CICADs are the latest in a family of publications from the International Programme on
Chemical Safety (IPCS) - a cooperative programme of the World Health Organization
(WHO), the International Labour Organisation (ILO), and the United Nations Environment
Programme (UNEP). CICADs join the Environmental Health Criteria documents (EHCs) as
authoritative documents on the risk assessment of chemicals. CICADs are concise
documents that provide summaries of the relevant scientific information concerning the
potential effects of chemicals upon human health and/or the environment. They are based
on selected national or regional evaluation documents or on existing EHCs. Before
acceptance for publication as CICADs by IPCS, these documents have undergone
extensive peer review by internationally selected experts to ensure their completeness,
accuracy in the way in which the original data are represented, and the validity of the
conclusions drawn. The primary objective of CICADs is characterization of hazard and dose-
response from exposure to a chemical. CICADs are not a summary of all available data on
a particular chemical; rather, they include only that information considered critical for
characterization of the risk posed by the chemical. The critical studies are,  however,
presented in sufficient detail to support the conclusions drawn. For additional information, the
 reader should consult the identified source documents upon which the CICAD has been
based. Risks to human health and the environment will vary considerably depending upon
the type and extent of exposure. Responsible authorities are strongly encouraged to
characterize risk on the basis of locally measured or predicted  exposure scenarios. To assist
 the reader, examples of exposure estimation and risk characterization are provided in
CICADs, whenever possible. These examples cannot be considered as representing all
possible exposure situations, but are provided as guidance only. The reader is referred to
EHC 170 for advice on the derivation of health-based guidance values. While every effort is
 made to ensure that CICADs represent the current status of knowledge, new information is
being developed constantly. Unless otherwise stated, CICADs are based on a search of the
scientific literature to the date shown in the executive summary. In the event that a reader
becomes aware of new information that would change the conclusions drawn in a CICAD,  the
 reader is requested to contact the IPCS to inform it of the new information, (description
from website)

International Programme for Chemical Safety, World  Health Organization, International
Labour Organisation, United Nations Environment Programme
Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
Name, Formula, synonyms, CASRN, ID numbers, MW, density, BP, MP, water solubility,
other solubility, partition coefficients, Log Koc, Log Kow, VP, HLC, production,
environmental fate, BMC/D, ENEV, IARC cancer class, TC(A), CTV, ECx, ICx, LCx, LDx,

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.inchem.org/paaes/cicads.html
Data Source Name
TV) Database
Identification Number
Data Source Description
Contaminant Exposure and Effects - Terrestrial Vertebrates (CEE-
27

CEE-TV is a database of contaminant exposure and effects for terrestrial vertebrates in
inner coastal regions of the Atlantic, Gulf, Pacific, and Alaskan areas of the United States.
The database was created via computerized literature searches, reviews of existing
databases, and integration of unpublished reports from conservation agencies, private
                                                         A4-29

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Proprietor
Contact Information
Type of Data Elements
groups and academic institutions. The database includes summary information on species,
collection date, site location, estuary name, contaminant concentrations, biomarker and
bioindicator responses, and source references. Searches  provide a list of compounds,
concentrations of organopesticides, total polychlorinated biphenyls congeners (PCBs),
dioxin-like PCBs, dioxin-like PCB Toxic  Equivalent Quotient (TEQ), inorganics,
organophosphorous insecticides, carbamates, and petroleum hydrocarbons.  There are
approximately 10,000 references of ecotoxicological exposure and effects information for
over 200,000 individuals representing a total of over 400 vertebrate species residing in
estuaries, (description from website)

Patuxent Wildlife Research Center, U.S. Geological Survey (USGS)

USGS Patuxent Wildlife Research Center
Barnett A. Rattner
12011 Beech Forest Road
Laurel, MD 20708-4041
Phone:(301)497-5671
Fax:(301)497-5675
Email: barnett_rattner@usgs.gov

Family, Year From, State, Latitude, Sample Size, Record  No, Order, Year To, Estuary,
Longitude, Genus/Species, Class, Location, HUC, Matrix
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
This source does not meet relevance criteria because it contains only information on
ecological toxicity.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.pwrc.usas.aov/contaminants-online/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Control of Communicable Diseases Manual; 17 ed.

39

Univ. of California, Berkeley. Brandon/Hill Medical List first-purchase selection (#278).
Previous edition, c1995, was authored by Abram S. Benenson. Pocket-sized manual, in
outline format, providing current information and recommendations for communicable
disease prevention.

(description from Amazon.com)

James Chin, editor, 2000.  American Public Health Association

James Chin
Clinical Professor of Epidemiology
School of Public  Health, UC Berkeley
456 Kentucky Avenue
Berkeley, California 94707-1735
USA

Tel: 510527 6252
Fax: 510527 7640
E-Mail: jchin@cdpc.com
jchin@socrates.berkeley.edu

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

Error! Hyperlink reference not valid.

                      A4-30

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Data Source Name

Identification Number
Data Source Description
Proprietor
CrossFire BEILSTEIN

41

CrossFire BEILSTEIN is a comprehensive structure and factual database covering over 8
million compounds and 35 million associated chemical properties and biological activity data
that describes "pharmacodynamics and environmental toxicology, transport, distribution, and
fate." The record contains documents from the BEILSTEIN Handbook of Organic
Chemistry as well as data from 120 peer reviewed journals. Subject coverage includes all
types of physicochemical properties, reaction information, spectral data, structural data, and
pharmacological and ecological data,  (description from website)

MDL Information Systems GmbH (formerly known as BEILSTEIN Informations systemme)
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
MDL Information Systems, Inc.
14600 Catalina Street
San Leandro, CA 94577
TEL: (510)895-1313
FAX: (510)614-3608

Chemical  Name, Effect, Species or Test-System, Route of Application, Kind of Dosing,
Method, Further  Details, Results, Half-Life Time; Laboratory Use and Handling; Ecological
Data; Concentration in the Environment; Transport and Distribution; Bioconcentration Factor;
Accumulation Half-life Time;  Accumulation Rate Constant; Elimination Half-Life Time;

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies and environmental fate data, providing an indicator of potential

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http://www.info.crossfirebeilstein.com/
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
Cumulative Estimated Daily Intake/Acceptable Daily Intake
(CEDI/ADI) Database

26

As part of the premarket notification process for food contact substances (FCSs), the
Office of Food Additive Safety (OFAS) is developing and making publicly available a
database of cumulative estimated daily intakes (CEDIs) and acceptable daily intakes (ADIs)
for a large number of FCSs. This database is referred to as the CEDI/ADI database. At this
time, the database contains CEDI/ADI information on an initial subset of food-contact
substances. OFAS is attempting to collect and review data for approximately 3000 FCSs for
inclusion into the CEDI/ADI database. As additional information becomes available, the
CEDI/ADI database will be updated. The CEDIs and ADIs are based on currently available
information and may be subject to revision on the basis of new information as it is submitted
or made available to OFAS. All potential notifiers are encouraged to approach OFAS with
new information on which to base CEDIs and ADIs and include such information in
notifications. See Preparation of Food Contact Notifications and Food Additive Petitions for
Food Contact Substances: Chemistry Recommendations. Concerning the database, OFAS
notes the following: The CEDI/ADI values listed at this early stage in the development of the
database are primarily for FCSs that may be classified as adhesives (21 CFR 175.105),
paper and paperboard components (21 CFR 176) and polymer adjuvants and production aids
(21 CFR 178). Information on many polymeric FCSs and constituents, such as monomers,
are presently not available. The CEDI values are expressed as dietary concentration (parts-
per-billion, ppb) and as intake (milligram/kilogram body weight/person/day, mg/kg bw/d) to
facilitate comparison to the applicable ADI value for the FCS. Many of the FCSs listed
below are only regulated for use under 21 CFR 175.105. In the absence of appropriate
information, such as migration studies, on which to base a numerical estimate of exposure,
OFAS assumes a default CEDI of 7 ppb (corresponding to a cumulative intake of 0.00035
mg/kg-bw/d). (description from website)

FDA - Center for Food Safety and Applied Nutrition

Office of Food Additive Safety (HFS-200)
Center for Food Safety and Applied  Nutrition
Food And Drug Administration
                      A4-31

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Type of Data Elements
Relevance Explanation
5100 Paint Branch Parkway
College Park, MD 20740-3835
(202)418-3100

Name, CASRN, ADI, CEDI, CUM DC

This source is considered relevant for the CCL Universe because it contains health effects
data.
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.cfsan.fda.aov/~dms/opa-edi.html
Data Source Name

Identification Number

Data Source Description
Proprietor

Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation

Retrievability Explanation

Source URL
Current Contents Search - Life Sciences - ISI

44

ISI® Current Contents/Life Sciences provides access to complete bibliographic information
from articles, editorials, meeting abstracts, commentaries, and all other significant items in
recently published editions of over 1,370 of the world's leading life sciences journals and
books in a broad range of categories.

Key Advantages & Capabilities:
- Helps users stay up-to-date in their research by enabling them to conduct fast,
multidisciplinary searches of the current life sciences literature
- Provides a complete picture of today's global research in the life sciences by combining
comprehensive coverage with numerous access points, exclusive search capabilities, and
optional coverage of past research and proceedings data
- Saves research time by providing one source for a variety of research data including
author abstracts, author addresses, and more information per bibliographic record than in
other resources
(description from website)

Thomson ISI

Thomson Scientific
North America
3501 Market Street
Philadelphia, PA 19104
Phone: +1 800 336 4474
+1 2153860100
Fax:+1  2153862911
E-mail: sales@isinet.com
Web: www.thomsonisi.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.isinet.com/cai-bin/irnlst/iloptions.cgi?PC=P
Data Source Name
Database of Sources of Environmental Releases of Dioxin-Like
Compounds  in the United States
                                                       A4-32

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Identification Number


Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
46
This database is a "repository of congener specific chlorinated dibenzo-p-dioxin/dibenzofuran
(CDD/CDF) emissions data from all known sources in the United States." Emissions can be
tracked overtime, homologue and congener profiles can be compared between and among
source categories, and source specific emission factors can be used to develop emission
estimates. The two reference years for information in the database are 1995 and 1987, with
data extracted from original test reports. The database covers both facility and non-facility
(e.g. mobiles sources like automobiles area sources) based emission data.  Most of the
emissions data concerns releases to air. (description from website)

EPA, ORD

DAVID CLEVERLY
Role:  CONTACT
Primary Phone #: 202-564-3238
Primary Email:  cleverly.david@epa.gov

Emmissions, Release to Air

This source is considered relevant for the CCL Universe because it contains information on
air emissions, which may indicate potential occurrence.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://oaspub.epa.aov/eims/eimsapi.detail?deid=20797&partner=ORD-NCEA
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Derek

241

DEREK for Windows uses a knowledge base, which contains alerts describing structure-
toxicity relationships, with an emphasis on the understanding of mechanisms of toxicity and
metabolism.

Chemical structures can be easily inputted into DEREK for Windows via its automatic link to
 ISIS/Draw or by importing MDL Molfiles or SDfiles. During an interactive session, DEREK
for Windows identifies the toxophore or substructure associated with toxicity and highlights
this to the user with a brief statement about the hazard it represents. At the touch of a button
 the user can access additional information concerning the structure-toxicity relationship
including literature references and supporting examples.

The knowledge base covers a wide variety of important toxicological end points, which
include carcinogenicity, mutagenicity, skin sensitisation, teratogenicity, irritation, and
respiratory sensitisation.

It is now well known that the physicochemical properties  of a compound play an important
role in determining potential toxicity. In recognition of this DEREK for Windows now
evaluates the predicted skin permeability of a chemical in order to predict its propensity to
induce skin sensitisation and photoallergenicity in humans. In the future, more of the
physicochemical properties of a chemical will be considered  in order to predict its potential
toxicity over a wide range of end points more accurately, (description from website)

LHASA Limited

LHASA Limited
Department of Chemistry
University of Leeds
Leeds, LS2 9JT, UK
Tel:+44 (0)113 343 6531
Fax:+44 (0)113 343 6535
Sales: info@lhasalimited.org
Support: support@lhasalimited.org
                                    or:
                                    lhasa.harvard.edu
                                                          A4-33

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Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Name, Description, References, Endpoint, Comments, LHASA Predictions: Genotoxicity,
Mutagenicity, Skin sensitisation

This source is considered relevant for the CCL Universe because it could be a source of
information on potential health effects.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria. The source does not contain data; it is a
model that might be used to generate estimates. The source is only available through a

http://www.chem.leeds.ac.uk/luk/derek/index.html
Data Source Name

Identification Number
Data Source Description
Proprietor

Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Derwent Crop Protection File (Derwent CROPU)

48

The CROPU File is a database that provides references to the worldwide journal literature on
all aspects of pesticides, including both biological and chemical information. Sources include
over 1,200 international journals, with coverage beginning in 1968 and conference
proceedings from 1985 to the present.  They cover analysis, biochemistry, chemistry, and
toxicology of all pesticides, (description from website)

Thomson Derwent - Derwent Information Limited, London, England and Alexandria, Virginia

Thomson Scientific
North America
3501 Market Street
Philadelphia, PA 19104
Phone: +1 800 336 4474
+1 2153860100
Fax:+1 2153862911
E-mail: sales@isinet.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.derwent.com/crop-protection/index.html
Data Source Name

Identification Number
Data Source Description
Derwent Crop Registry File (Derwent CROPR)

47

CROPR is a factual chemical registry database for chemicals in the Crop Protection File
(CROPU) database. Each reference lists the biological activity and chemical substructure
characteristics of an individual compound.  The database supports structure-activity
searching (e.g., to generate a list of compounds with a specific structural feature that share
a common activity). Compounds selected in this database can then be searched in the
CROPU database for more extensive bibliographic information.  The database draws on
scientific journals, conference proceedings, meeting reports, and basic patents. File data
Proprietor
Contact Information
include references on more than 8,000 pesticides from 1985 to the present, (description
from website)

Thomson Derwent - Derwent Information Limited, London, England and Alexandria, Virginia

Thomson Scientific
North America
                                                        A4-34

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Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
3501 Market Street
Philadelphia, PA 19104
Phone: +1 800 336 4474
+1 2153860100
Fax:+1 2153862911
E-mail: sales@isinet.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.cas.org/ONLINE/DBSS/croprss.html
Data Source Name
Identification Number
Data Source Description
Derwent Drug File (Derwent DRUGU)
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
49

The Derwent Drug File contains 1.5 million bibliographic references from the worldwide
pharmaceutical literature from 1964 to the present.  The file also contains a structure-
searchable database which can be searched for specific compounds and their activities, and
provides bibliographic references. Subject coverage includes all aspects of drugs, such as
analysis, biochemistry, structure-activity relationships, pharmacokinetics,  metabolism,
toxicology, and therapeutics.  References are drawn from over 1,100 medical and scientific
journals and conference proceedings. The structure-searchable segment of the database
contains over 85,000 records, (description from website)

Thomson Derwent - Derwent Information Limited, London, England and Alexandria, Virginia

Thomson Scientific
North America
3501 Market Street
Philadelphia, PA 19104
Phone: +1 800 336 4474
+1 2153860100
Fax:+1 2153862911
E-mail: sales@isinet.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.
Retrievability Explanation

Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.derwent.com/drugfile/index.html
Data Source Name
Identification Number
Data Source Description
Design Institute for Physical Property Data (DIPPR)

51

DIPPR contains "rigorously evaluated" data for pure component physical property data for
commercially important chemicals.  Coverage includes 29 constant properties and 15
temperature dependent properties for 1,743 commercially important chemicals. DIPPR data
                                                        A4-35

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Proprietor

Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
are compiled from published research data from 1982 to the present,  (description from
website)

Supported by the American Institute of Chemical Engineers and maintained by Brigham
Young University

Van Yang
DIPPR®801 Project Coordinator
350 CB, PO Box 24100
Provo, Utah 84602-4100
801 -422-9366 / fax: 801 -422-0517
dippr@byu.edu

Name, MW, Critical Temperature, Pressure, Volume, and Compressibility Factor, MP, Triple
Point Temperature and Pressure, Normal Boiling Point, Liquid Molar Volume, Enthalpy of
Formation (Ideal Gas and Standard State), Gibbs Energy of Formation (Ideal Gas and
Standard State), Entropy (Ideal Gas and Standard State), Enthalpy of Fusion, Standard Net
Heat of Combustion, Acentric Factor, Radius of Gyration, Solubility Parameter, Dipole
Moment, Van derWaals Volume and Area, Refractive Index, Flash Point, Upper and Lower
Flammability Limits, Autoignition Temperature, Liquid and Solid Density, Liquid and Solid
Vapor Pressure, Heat of Vaporization, Ideal Gas, Liquid, and Solid Heat Capacity, Second
Virial Coefficient, Vapor and Liquid Viscosity, Vapor, Liquid, and Solid Thermal Conductivity,

This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.

It meets considerations because it is peer reviewed.

This source is not  redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://dippr.bvu.edu
Data Source Name


Identification Number
Data Source Description
Proprietor

Contact Information
Developmental and Reproductive Toxicology/Environmental
Teratology Information Center (DART®/ETIC) Database

45

DART/ETIC is a bibliographic database on the National Library of Medicine's (NLM)
Toxicology Data Network (TOXNET®). It covers teratology and other aspects of
developmental and reproductive toxicology. It contains over 100,000 references to literature
published since 1965. DART/ETIC is funded by the U.S. Environmental Protection Agency,
the National Institute of Environmental Health Sciences, the National Center for
Toxicological  Research of the Food and Drug Administration, and the NLM. (description from
website)

National Library of Medicine - Part of NLM TOXNET, funded by EPA, NIH, the FDA's
National Center for Toxicological Research, and NLM

Specialized Information Services
National Library of Medicine
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Telephone: (301) 496-1131
FAX (301) 480-3537
e-mail: tehip@teh.nlm.nih.gov
URL: http://sis.nlm.nih.gov

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for

                      A4-36

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         Identifying the Universe
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      August 2009
Source URL
automated retrieval.

http://toxnet.nlm.nih.aov/cai-bin/sis/htmlgen7DARTETIC
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Dictionary of Substances and Their Effects - Knovel

50

This 2004 electronic version of the original seven-volume collection of vital information has
been updated to contain approximately 4,600 chemicals and their impact on the environment.
 Detailed information about the toxicity of the chemicals, physical properties and regulatory
requirements is also presented. All information is presented with complete references
detailed at the  end of each file. A live table is available, listing all chemicals and their
physical properties. The table contains hot links to an image of the chemical structure as well
 as a link to the detailed information directly from the book. The detailed files can also be
accessed by browsing the table of contents. A newly added field allows records to be sorted
or filtered on the update date as this title will be continually updated. Chemicals can be
searched for by their chemical names as well as synonyms, molecular formulas, CAS
Registry and RTECS numbers. The data (text) files can be searched for keywords, and the
fields in the live table can be searched for physical properties, registry numbers, and
synonyms, (description from website)

Knovel

Knovel Corporation
13 Eaton Avenue
Norwich, NY 13815 USA
Tel: 1-607-337-5600
Fax:  1-607-334-9097
E-mail: info@knovel.com

Toxicity, Physical Properties, Regulatory Requirements, References

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http://www.knovel.com/knovel2/default.isp
Data Source Name
Distributed Structure Searchable Toxicity Public Database Network
(DSSTox)
Identification Number
Data Source Description
Proprietor
Contact Information
53

Info from the following website: http://www.epa.gov/nheerl/dsstox/
The Distributed Structure-Searchable Toxicity (DSSTox) Database Network provides a
community forum for publishing standard format, structure-annotated chemical toxicity data
files for open public access. DSSTox databases are compilations and reformulations of
public databases that are made freely available on this website for any public use. The
DSSTox project has placed considerable emphasis, however, on implementing data and
documentation standards that  are intended to encourage consistency in the use and reporting
of such data. This not only creates common public expectations and understanding of these
data, but also facilitates study reproducibility and greater community awarenessand
improvement of these data, (description from website)

EPA

DSSTox Technical Support
email: dsstox_support@epa.gov
Ann Richard
DSSTox Project Leader
email: richard.ann@epa.gov
919-541-3934
                                                         A4-37

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      August 2009
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
TD50

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source meets retrievability criteria because the relevant data can be extracted in tabular
format.

http ://www. epa.gov/nheerl/dsstox/
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Division of Bacterial  and Mycotic Diseases (DBMD) - Disease
Information Listing

52

This database gathers in one place CDC's online resources concerning approximately 50
infectious bacterial diseases. For each infectious agent, a summary of the health
endpoints, transmission characteristics, and disease prevalence is given. At-risk groups and
current research are also summarized, and additional resources are listed for many
contaminants, (description from website)

CDC - Division of Bacterial and Mycotic Diseases

National Center for Infectious Diseases
Division of Bacterial and Mycotic Diseases
1600 Clifton Rd
MS
Atlanta GA 30333

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
Completeness Explanation       It meets considerations because it is peer reviewed.
Redundancy Explanation
Retrievability Explanation

Source URL
This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.cdc.gov/ncidod/dbmd/diseaseinfo/default.htm
Data Source Name

Identification Number
Data Source Description
EC Water Directive

242

The old Drinking Water Directive of 1980 has provided the consumer security for drinking
water quality throughout the EU. However, it was both out of date as concerns
scientific/technical basis (original proposal was made in 1975) and the managerial approach.
                                   Main thrust of the Commission Directive are:

                                   Review of parametric values, and where necessary strenghtening them in accordance with
                                   the latest available scientific knowledge (WHO Guidelines, Scientific Committee on
                                   Toxicology and Ecotoxicology)
                                   Increased transparency:
                                   "Tapwater Directive" i.e. the point of use is the point of compliance with the quality standards

                                   reference to ISO/CEN standards
                                   obligation to report on quality
                                   obligation to inform the consumer on drinking water quality and measures that they can take
                                   to comply with the requirements of the Directive -in particular for lead- when the non-
                                   compliance is because of the domestic distribution system (internal pipes, plumbing etc)
                                                        A4-38

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Proprietor
Contact Information
Type of Data Elements
Streamlining legislation to parameters essential for health and environment: 66 parameters in
the old directive have been reduced to 48 (50 for bottled waters)in the new one, including 15
new parameters
Main changes in parametric values:

Lead: reduced from 50 |jg/l to 10 |jg/l, 15 years transition period to allow for replacing lead
distribution pipes
Pesticides:values for individual substances and for total pesticides retained (0.1 |jg/l /
0.5|jg/l), plus additional, more stringent ones introduced for certain pesticides (0.03|jg/l)
Copper: value reduced from 3 to 2 mg/l
Standards introduced for new parameters like trihalomethanes, trichloroethene and
tetracholoroethene, bromate, acrylamide etc.
This new Directive provides a sound basis for both the consumers throughout the EU and
the suppliers of drinking water.
Implementation deadlines:

The Directive entered into force on 25 December 1998.
Member States have 2 years i.e. until 25 December 2000 to transpose the Directive into
national legislation.
Member States have 5 years i.e. until 25 December 2003 to ensure that the Drinking water
complies with the standards set, except for Bromate (10 years), Lead (15 years) and
Trihalomethanes (10 years),  (description from website)

European Community

European Commission
Environment DG
Information  Centre
Office: BU-9 01/11
B-1049 Brussels
Belgium
Fax: +32 (0)2 299.61.98

Parameter,  Parametric value, Unit, Notes, Trueness % of parametric value, Precision % of
parametric value, Limit of detection % of parametric value, Conditions
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Data Source Name
Identification Number
Data Source Description
This source is considered relevant for the CCL Universe because it contains regulatory
limits for contaminants in drinking water.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://ec.europa.eu/environment/water/water-framework/index en.html

Ecological Incident Information System

256

After a field has been treated with pesticides, wildlife may be exposed to these chemicals by
several routes. When the exposure is high relative to the toxicity of the pesticide, wildlife
may be killed or visibly incapacitated. Such events are called ecological incidents.

Many  of these ecological incidents are probably not observed or reported, but when they are
reported to the proper authority (usually a state agency), they are investigated and an
incident report is generated.

In 1992, the Agency created a database called The Ecological Incident Information System
(EMS) to store information extracted from these incident reports.

The two primary sources of incident reports are pesticide registrants and government
agencies. Under section 6(a)(2) of the pesticide law FIFRA, pesticide registrants or
manufacturers are required to  report to EPA any information related to known adverse
effects to the environment caused by their registered pesticides.

The second major source of information  is investigative reports which are voluntarily
submitted to the Agency from state and other federal agencies that oversee agriculture,
wildlife, natural resources, and environmental quality. Diagnostic reports are also obtained
from the National Wildlife Health Institute (USGS), the Patuxent Wildlife Research Center
(USGS), the Southwest Wildlife Cooperative Disease Study, and state wildlife forensic
laboratories. Information is also extracted from accounts of ecological incidents reported in
                                                           A4-39

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Proprietor
Contact Information

Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
newspapers and reliable internet sources.

The ENS was originally built in dBase III Plus, but was recently converted into a Lotus
Approach application. It is a relational database consisting of 89 distinct fields contained
within 13 related data tables.

Information in EMS records, if available, include the data and location of the incident, type
and magnitude of affects observed in various species, use(s) of pesticides known or
suspected of contributing to the  incident, and the results of any chemical residue and
cholinesterase activity analyses conducted during the incident  investigation.

Ecological incidents play an important role in the Agency's risk assessment and decision-
making process. Widespread ecological incidents for a pesticide may confirm a risk that was
 predicted by risk assessment models, or it may indicate that the actual risk is greater or
less than that predicted by the model, (description from website)

EPA

Nicholas Mastrota at Mastrota.Nicholas@epa.gov or call 703-305-5247

Location of the Incident, Type and Magnitude of Affects, Use(s) of Pesticides, Results of
Chemical Residue and Cholinesterase Activity Analyses

This source does not meet relevance criteria because it contains only information on
ecological toxicity.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.
Retrievability Explanation
Source URL
This source meets retrievability criteria because it is in tabular format.

http://www.epa.aov/oppefed1/general/databasesdescription.8-15
Data Source Name

Identification Number
Data Source Description
Proprietor

Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Ecology of Aquatic Hyphomycetes

56

Aquatic hyphomycetes were discovered 50 years ago by C.T. Ingold. They remained a
relatively obscure group until their role as intermediaries between deciduous leaves and
stream invertebrates was established some 20 years ago. This book, for the first time,
provides a comprehensive summary and critical evaluation of the biology and ecology of
these organisms. A special effort was made to evaluate the potential and actual insight that
have been or will be derived from work in related disciplines such as the ecology of other
fungal groups, stream ecology, or population ecology. The topics treated include the basic
life history of the fungi and the potential role of wood, a discussion of how the fungi have
adjusted to life in running water, their interactions with invertebrates, the attachment and
germination of their spores, what is known about sexual reproduction, how water chemistry
may influence their distribution and  activity, how they react to human degradation of their
environment, and a summary of the research done on the Indian subcontinent. The volume
is of special interest to mycologists  and stream ecologists and should facilitate the entry of
new workers into this exciting area. -This text refers to the Hardcover edition.

(description from Amazon.com)

Golley et al (eds.), Springer-Verlag: New York, 1992

Springer-Verlag New York
175 Fifth Avenue
New York, NY 10010
Phone: 212-460-1500
Fax:201-348-4505

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for

                      A4-40

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Source URL
automated retrieval, and it is only available through a subscription.

Error! Hyperlink reference not valid.
Data Source Name


Identification Number
Data Source Description
Proprietor
ECOTOX - A Database of Toxic Effects to Aquatic and Terrestrial
Species

57

ECOTOX "represents an integration of AQUIRE, PHYTOTOX, and TERRETOX, which are
three existing EPA databases that contain ecotoxicity information for aquatic life, terrestrial
plants, and wildlife, respectively."  ECOTOX also includes the Ecological Effects database of
toxicity data for aquatic and terrestrial species,  provided by the EPA, Office of Pesticide
Programs (OPP), Ecological Effects Branch. Published papers on toxicology are reviewed,
and data are abstracted and reported in the appropriate database. Currently, ECOTOX
includes over 200,000 toxic effect listings from 16,899 references for more than 6,000
chemicals and 3,800 aquatic and terrestrial species, (description from website)

EPA Office of Research and Development - EPA, ORD, and NHEERL, Mid-Continent
Ecology Division
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
ECOTOX Support
Mid-Continent Ecology Division
6201 Congdon Boulevard
Duluth, MN 55804
Telephone: 218-529-5225
Fax: 218-529-5003
E-mail: ecotox.support@epa.gov

Endpoint, Effect, Effect Measurement, Trend, Effect %, Media Type, Duration, Exposure
Type,  Concentration (ug/L), Significance, Level, Response Site, BCF

This source does not meet relevance criteria because it contains only information on
ecological toxicity.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.

http://www.epa.gov/ecotox/ecotox horne.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Elsevier BIOBASE

63

Elsevier BIOBASE is a bibliographic database of current information on international
biological research. Subject coverage includes applied microbiology, cancer research,
clinical chemistry, ecological and environmental sciences, endocrinology and metabolism,
molecular biology, and toxicology. The database includes bibliographical and abstract
information from over 1,900 source journals, and contains records from 1994 to the present.
 (description from website)

Elsevier Science Bibliographic Database, Amsterdam, the Netherlands

NORTH AMERICA
ebd-marketing@elsevier.com
Tel:+1 8884374636
Fax:+1 2126333975

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.

                      A4-41

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Redundancy Explanation
Retrievability Explanation

Source URL
This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.elsevier.nl/homepage/sah/spd/site/
Data Source Name

Identification Number
Data Source Description
EMBASE

65

EMBASE is a bibliographic database of international literature on biomedical and
pharmaceutical fields. The database consists of abstracts and bibliographic information
from over 4,400 journals, and many books, conference proceedings, and reports, for a total
of over nine million citations and abstracts from 1974 to the present. Subject coverage
includes basic biological science (relevant to human medicine), biochemistry, clinical and
Proprietor

Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
experimental medicine, drugs, environmental science, pharmacology, pollution control, public
 health, and toxicology.  EMBASE also provides access to drug literature, searchable by
chemical, trade, or manufacturer name, (description from website)

Elsevier Science Bibliographic Database, Amsterdam, the Netherlands

NORTH AMERICA
em base-usa@elsevier.com
Tel:+1  8884374636
Fax:+1 2126333975

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.elsevier.nl/homepage/sah/spd/site/
Data Source Name

Identification Number
Data Source Description
Proprietor

Contact Information
Endocrine Disrupter Priority Setting Database (EDPSD)

59

This database includes information queried from over 30 different databases specifically
relevant to health effects and exposure to potential endocrine disrupting chemicals, in readily
exportable tabular form. The data are organized into categories of exposure-related
information, effects-related information, combined exposure and effects-related information,
and specially targeted priorities (e.g., mixtures).  More specifically, the database includes
many types of occurrence and health-effects information such as water and tissue
occurrence, and specific human-health endpoints, where available. Much of the data were
manipulated to provide summary statistics, weighting, or ranking  prior to entry into the
database. Over 87,000  chemicals, including High Production Volume (HPV) Chemicals
(regulated under the Toxic Substances Control Act (TSCA)) and Pesticide Inert Chemicals,
are included,  (description from website)

EPA Office of Prevention, Pesticides, and Toxic Substances;  EPA, Office of Science
Coordination and Policy

John D. Walker
7401M
US EPA Headquarters
Ariel Rios Building
1200 Pennsylvania Avenue, N. W.
Washington, DC 20460
202-564-7526
                                                         A4-42

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        Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Type of Data Elements
Relevance Explanation


Completeness Explanation
Redundancy Explanation
walker.johnd@epa.gov

Name, CASRN, HE and Occurrence data

This source is considered relevant for the CCL Universe because it contains data elements
derived from toxicological studies and unique elements derived for measurements of
contaminants in water, providing an indicator of occurrence.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.
Retrievability Explanation

Source URL
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.

http://www.ergweb.com/endocrine/
Data Source Name
Solutions
Identification Number
Data Source Description


Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation
Retriev ability Explanation

Source URL
Environmental Abstracts - LexisNexis Academic and Library
68

LexisNexis Environmental Abstracts allows user to search abstracts from thousands of
environmental journals, conference papers, and Federal government reports with links to
selected full text,  (description from website)

LexisNexis

LexisNexis Academic & Library Solutions
4520 East-West Hwy
Bethesda MD 20814.3389 USA
Phone: 800.638.8380
Phone: 301.654.1550
Fax 301.657.3203
email: academicinfo@lexisnexis.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does  not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does  not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.lexisnexis.com/academic/1univ/envir/2ea.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Environmental Data Registry (EDR)

60

The EDR catalogs the EPA's major data collections and helps locate environmental
information of interest. EDR does not store numerical data, but includes descriptive
metadata records for data kept elsewhere. The system integrates several collections of
EPA metadata, including data elements and chemical identification information.  The
integrated information in EDR is accessed by the SRS and the CRS. (description from
website)

EPA

Michael Pendleton
United States Environmental Protection Agency
Office of Environmental Information
1200 Pennsylvania Avenue, NW
Mail Code 2822-T
                     A4-43

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
                                  Washington, DC 20460
                                  email: pendleton.michael@epa.gov
                                  Phone:(202)566-1658
                                  Fax:(202)566-1639
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.epa.gov/edr/
Data Source Name

Identification Number

Data Source Description
Proprietor

Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Environmental Defense Fund (EOF) Chemical Profiles

58

Chemical profiles include information on over 11,000 chemicals, mostly those that are used
in large amounts or regulated under major environmental laws in the United States and/or
Canada. For the 650 chemicals in the TRI, the chemical profiles incorporate environmental
release, human health hazards, chemical use, regulatory coverage, basic hazard testing, and
safety assessment information to track the chemicals. The human health hazard data for
TRI chemicals is compiled from over 100 separate data sources on toxicology. Chemicals
not in TRI also  have profiles, but with more limited data availability. Some ranking
information is available for a subset of the chemicals covered in the database, (description
from website)

Environmental  Defense Fund (EOF)

National Headquarters
257 Park Avenue South
New York, NY 10010
Telephone: (212) 505-2100
Fax:(212)505-2375

Name, CASRN, recognized health hazards, suspected health hazards, general production
category;

This source is considered relevant for the CCL Universe because it contains information on
potential health effects.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria.  This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.

http://www.scorecard.org/chemical-profiles/
Data Source Name

Identification Number
Data Source Description
Environmental Fate Databases

258

EPA's Office of Pesticide Programs (OPP) collects and reviews a variety of environmental
fate studies submitted by pesticide manufacturers in support of the registration of pesticide
products.

Environmental fate studies describe what happens to a pesticide in soil, water, and air after it
 has been applied and include the following types of studies:
                                                        A4-44

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
                                   product chemistry,
                                   metabolism,
Proprietor
Contact Information

Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
hydrolysis,
photolysis,
field dissipation,
bioaccumulation,
adsorption/desorption and leaching.

After reviewing the data in these studies, OPP scientists summarize the information in Data
Evaluation Reports (DERs), Reregistration Eligibility Decision Documents (REDs), science
chapters, Emergency Use Exemptions, and other environmental fate reports.

In 2000, OPP initiated the development of a pesticide environmental fate database which will
allow the user to search and view the data, query the fate database, and print reports that
are found in these summary reports.

Presently, this database contains environmental fate and transport data for about 250
pesticide active ingredients. The Pesticide Program plans to complete the initial version of
this database by the end of 2002 and will  be adding additional active ingredients during the
next two years,  (description from website)

EPA

Larry Liu at Liu.Larry@epa.gov or call 703-305-5372

Environmental Fate Studies including, product chemistry, metabolism, hydrolysis,
photolysis, field dissipation, bioaccumulation, adsorption/desorption and leaching

This source is considered  relevant for the CCL Universe because it contains environmental

It meets considerations because it meets  all NDWAC minimum data requirements.

This source is redundant with BIOLOG, BIODEG, CHEMFATE, and DATLOG. EFDB simply
provides a link to,  and leads to, BIOLOG,  BIODEG, CHEMFATE, and DATALOG.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.epa.aov/oppefed1/general/databasesdescription.htm - efd
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Environmental Health Criteria (EHC) Monographs

61

Comprehensive data from scientific sources for the establishment of safety standards and
regulations

EHC publications are monographs designed for scientists and administrators responsible for
the establishment of safety standards and regulations. This series issued by the
International Programme on Chemical Safety (IPCS), provides basic scientific risk
evaluation of a wide range of chemicals and groups of chemicals.

EHC monographs are based on a comprehensive search of available original publications,
scientific literature and reviews and examine: the physical and chemical properties and
analytical methods; sources of environmental and industrial exposure and environmental
transport, chemobiokinetics and metabolism including absorption, distribution, transformation
and elimination; short and long term effects on animals (carcinogenicity, mutagenicity, and
teratogenicity); and finally, an evaluation of risks for human health and the effects on the
environment, (description from website)

International Programme for Chemical Safety, World Health Organization

The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International  Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca
Type of Data Elements
Name, Synonyms, formula, structure, CASRN, ID numbers, MW, BP, MP, FP, density,
flash point, flammable limits, vapor density, VP, water solubility, other solubility, odor
threshold, taste threshold, Log Kow, Log Koc, GV, CCx, CVx, ECx, LCx, LDx, LO(A)EL,
                                                          A4-45

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EPA-OGWDW
        Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
This source is considered relevant for the CCL Universe because it contains data elements
(LDx, LO(A)EL, NO(A)EL) from toxicological studies.

It meets considerations because it is peer reviewed.

This source is redundant, as it is wholly available as part of INTOX (source 105).

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.inchem.org/paaes/ehc.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Environmental Information  Management System (EIMS)

62

The EIMS system "stores, manages, and delivers descriptive information for data sets,
databases, documents, models, multimedia, projects, and spatial environmental information".
 The system "stores and maintains descriptive information in a relational database and
refers to the products (i.e., data, documents, etc.) stored either within EIMS or as distributed
external files", (description from website)

EPA, ORD

ORD Helpdesk:
Phone:  919-380-4588
Fax:  919-466-0055
ord.omishelpdesk@epa.gov

Analytical Method, Concentration, # Samples Contaminated, Sensitivity of Sampling Design,
 State, Basin, Primary Water Use, Project Period, Month, Week

This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.epa.gov/eims/eims.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Environmental Monitoring and Assessment Program (EMAP)

64

EMAP is a database of geographical and water quality data for agro-ecosystems, the Great
Lakes, estuaries, landscape ecology, surface waters, and wetlands. Analytical data are
currently available for estuaries and some surface waters only. Data on water chemistry,
soil chemistry, pesticide use, and other data for specific locations are included, (description
from website)

EPA

Environmental Monitoring and Assessment Program
Melissa Hughes
US EPA
Atlantic Ecology Division
27 Tarzwell Drive
                                  Narragansett, Rl 02882
                                  email: hale.stephen@epa.gov
                                  email: emap@epa.gov
                                  Phone: 401 7823184
                                  Fax: 401 782 3030
                                 Assemblage Counts, Chlorophyll Data, Assemblage Metrics, Counts Data, Diatom Data,


                                                       A4-46

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EPA-OGWDW
        Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
This source is considered relevant because it contains geographical and water quality data,
providing an indicator of potential occurrence.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.

http://www.epa.aov/emap/html/data/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retriev ability Explanation

Source URL
Environmental Monitoring Methods Index (EMMI)

67

The EPA's Environmental Monitoring Methods Index (EMMI) is its official analytical methods
database, containing methods for over 3,800 water contaminants. EMMI allows the user to
access an extensive list of analytes and analytical methods. The database contains method
abstracts that include sample collection, storage, preservation, preparation, extraction, and
analysis information, (description from website)

EPA

U.S. Environmental Protection Agency
Office of Water (4101M)
1200 Pennsylvania Avenue, N.W.
Washington, D.C. 20460
email: OW-GENERAL@epa.gov

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://vosemite.epa.aov/water/owrccatalog.nsf/
Data Source Name
Identification Number
Environmental Mutagen Information Center Database (EMIC)
66
Data Source Description


Proprietor

Contact Information
Type of Data Elements

Relevance Explanation
EMIC is a bibliographic database on the NLM TOXNET® system. It covers chemical,
biological, and physical agents that have been tested for genotoxic activity.  It contains
some 20,000 literature citations published since 1991.  (description from website)

National Library of Medicine; prepared by EMIC/Oak Ridge National Laboratory
(EMIC/ORNL), Oak Ridge, Tennessee, for the Federal government

Specialized Information Services
NLM/NIH
2 Democracy Plaza, Suite 510
6707 Democracy Blvd., MSC 5467
Bethesda, MD 20892-5467
Phone: 301- 496-1131 (local and international)
Fax: 1-301-480-3537
Toll Free:  1-888-FINDNLM
E-mail: tehip@teh.nlm.nih.gov

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
                     A4-47

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://toxnet.nlm.nih.aov/cai-bin/sis/htmlgen7EMIC
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Environmental Pollution - Elsevier Science

69

Environmental Pollution is an international journal that addresses issues relevant to the
nature, distribution and ecological effects of all types and forms of chemical pollutants in
air, soil and water. The Editors welcome articles based on original research, findings from
re-examination and interpretation of existing data and reviews of important issues. In
addition, the journal also publishes articles on new methods of detection, study and
remediation of environmental pollutants.

All types of pollution are covered, including atmospheric pollutants, detergents, fertilizers,
industrial effluents, metals, mining wastes, oil, pesticides, plastics, radioactive materials and
sewage, (description from database)

Elsevier

Customer Service Department
6277 Sea Harbor Drive
Orlando, FL 32887-4800 USA
Email: usjcs@elsevier.com
US Customers:
Toll Free:+1 (877)839-7126
Fax:+1 (407)363-1354

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.

It meets  considerations because it is peer reviewed.
Redundancy Explanation
Retrievability Explanation

Source URL
This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http://www.elsevier.nI/inca/publications/store/4/0/5/8/5/6/
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Environmental Science and Technology

70

ES&T is a unique source of information for scientific and technical professionals in a wide
range of environmental disciplines. In its research section, contributed material may appear
as current research papers, policy analyses, or critical reviews. Also included is a magazine
section called the A-Pages that provides authoritative news and analysis of the major
developments, events, and challenges shaping the field, (description from website)

American Chemical Society

American Chemical Society
1155 16th St., N.W.
Washington, DC 20036
Phone: (202) 872-4582
Fax: (202) 872-4403
E-mail: est@acs.org
                                                         A4-48

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EPA-OGWDW
        Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http://pubs.acs.ora/iournals/esthag/index.html
Data Source Name


Identification Number

Data Source Description
Proprietor
Contact Information
Environmental Sciences and Pollution Management - Cambridge
Scientific Abstracts

71

This multidisciplinary database, provides unparalleled and comprehensive coverage of the
environmental sciences. Abstracts and citations are drawn from over 5980 serials including
scientific journals, conference proceedings, reports, monographs, books and government
publications. Major areas of coverage include: Agricultural biotechnology, Air quality, Aquatic
 pollution, Bacteriology, Ecology, Energy resources, Environmental biotechnology,
Environmental engineering, Environmental impact statements (U.S.), Hazardous waste,
Industrial hygiene, Microbiology related to industrial & environmental issues, Pollution: land,
air, water, noise, solid waste, radioactive, Risk assessment, Safety science, Toxicology &
toxic emissions, Water pollution, Waste management, Water resource issues, (description
from website)

Cambridge Scientific Abstracts

Cambridge Scientific Abstracts
7200 Wisconsin Avenue
Bethesda, MD 20814 USA
Voice: 800-843-7751 (in N. America)
Voice: +1 301-961-6700 (worldwide)
Fax:+1 301-961-6720
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
Email: sales@csa.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.csa.com/csa/ids/databases-collections.shtml - environmental
Data Source Name


Identification Number
Data Source Description
Proprietor
European Inventory of Existing Commercial Substances (EINECS)
Information System

55

The online EINECS Information System allows you, through the European Inventory of
Existing Commercial Substances (EINECS), to find General information concerning a
chemical substance like CAS number, EINECS number, Substance Name and Chemical
Formula. The current EINECS contains 100 196 chemical substances.
(description from website)

European Chemicals Bureau (ECB)

                     A4-49

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Contact Information

Type of Data Elements
Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
sharon.munn@jrc.it
remi.allanou@jrc.it

Name, CASRN, EINECS ID, LDx, NOAEL (not available for all contams)

This source does not meet relevance criteria because it contains a chemical list that is not
related to health effects or occurrence.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://ecb.irc.it/
Data Source Name

Identification Number
Data Source Description


Proprietor

Contact Information
Eurosurveillance

72

EuroSurveillance publishes: weekly and monthly reports on infectious disease outbreaks in
member countries; epidemiological updates; and analysis of disease trends in Europe.
(description from website)

Eurosurveillance; European Commission (EC)

Eurosurveillance Weekly
Health Protection Agency
Communicable Disease Surveillance Centre
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
61 Colindale Avenue
London NW9 5EQ
eurosurveillance.weekly@hpa.org.uk
Tel. 44 (0)20-8200 6868
extension 4417
Fax: 020 8200 7868

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.eurosurveillance.org/index-02.asp
Data Source Name

Identification Number
Data Source Description
Everything Added to Food in the United States (EAFUS) Database

54

This is an informational database maintained by the U.S. Food and Drug Administration
(FDA) Center for Food Safety and Applied Nutrition (CFSAN) under an ongoing program
known as the Priority-based Assessment of Food Additives (PAFA). It contains
administrative,  chemical and toxicological information on over 2000 substances directly
added to food,  including substances regulated by the U.S. Food and Drug Administration
(FDA) as direct, "secondary" direct, and color additives, and Generally Recognized As Safe
(GRAS) and prior-sanctioned substances. In addition, the database contains only
administrative and chemical information on less than 1000 such substances. The more than
3000 total substances together comprise an inventory often referred to as "Everything"
Added to Food in the United States (EAFUS).

This list of substances contains ingredients added directly to food that FDA has either
approved  as food additives or listed or affirmed as GRAS. Nevertheless, it contains only a
partial list of all food ingredients that may in fact be lawfully added to food, because under
                      A4-50

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Proprietor

Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
federal law some ingredients may be added to food under a GRAS determination made
independently from the FDA. The list contains many, but not all, of the substances subject
to independent GRAS determinations, (description from website)

FDA - Center for Food Safety and Applied Nutrition; CFSAN, Office of Food Additive
Safety

CFSAN Outreach and Information Center
Center for Food Safety and Applied Nutrition
5100 Paint Branch Parkway (HFS-555)
College Park, MD 20740
Toll-Free Information Line:
1-888-SAFEFOOD (1-888-723-3366)

Name, CASRN, status of toxicology information

This source is considered relevant for the CCL Universe because it contains a list of
chemicals that is related to potential exposure.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://vm.cfsan.fda.aov/~dms/eafus.html
Data Source Name
Identification Number
Data Source Description
Proprietor

Contact Information

Type of Data Elements



Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Extension TOXicology NETwork (EXTOXNET)

73

Several databases are maintained under EXTOXNET that include various types of pesticide
toxicology and environmental chemistry information, such as discussions of Toxicological
Issues of Concern (TICs); toxicology newsletters; other resources for toxicology
information; toxicology fact sheets; Pesticide Information Profiles (PIPs); and Toxicology
Information Briefs (TIBs). TIBs are informational briefs that are designed to help the public
understand principles of toxicology. PIPs are documents that provide specific pesticide
information relating to health and environmental effects, but are not based on an exhaustive
literature search, so they may not be complete in their coverage or data reporting.
Information includes toxicological effects, regulatory status, chemical properties,
formulations, synonyms/trade names, chemical class, ecological effects, environmental
fate, degradation, and major manufacturers, presented in a profile format. More than 180
pesticides are included in the database,  (description from website)

Produced and maintained through the cooperative effort of the University of California-
Davis, Oregon State University, Michigan State University, Cornell University, and the

Terry L. Miller
extoxnet@ace.orst.edu

Name, CASRN, trade names, regulatory status, LD50, critical effect, chronic toxicity,
reproductive, teratogenic, mutagenic, cancinogenic, organ toxicity, ecotoxicity, half life in
soil and water, water solubility, MW, other solubility, MP, VP, partition coefficient, adsorption
coefficient, ADI, MCL, RfD,  PEL, HA, TLV

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://ace.ace.orst.edu/info/extoxnet/
                                                         A4-51

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         Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Facilities Index Data System

274

FINDS contains entries for sites and facilities regulated by the US EPA under a variety of
statutes. Some of these include RCRA, CERCLA, the Clean Air Act, the Clean Water Act,
TSCA, FIFRA, TRIS, and more.

SUBJECT COVERAGE :

Geographic location and identification data
Classification codes for the site
Listing of EPA and state databases containing more information about the site
(description from website)

National Information Services Corporation (NISC)

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul  Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Type of Data Elements


Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Geographic location and identification data,
Classification codes for the site, Listing of EPA and state databases containing more
information about the site

This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.nisc.com/cis/details/finds.htm
Data Source Name

Identification Number
Data Source Description
Proprietor

Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) List

289

The primary focus of FIFRA was to provide federal control of pesticide distribution, sale,
and use. EPA was given authority under FIFRA not only to study the consequences of
pesticide usage but also to require users (farmers, utility companies, and others) to register
when purchasing pesticides.

All pesticides used in the U.S. must be registered (licensed) by EPA. Registration assures
that pesticides will be properly labeled and that if in accordance with specifications, will not
cause unreasonable harm to the environment.

EPA
Unknown

This source is considered relevant for the CCL Universe because it contains a list of
chemicals that is related to potential exposure.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source meets retrievability criteria because it is accessible through EPA's Substance
Registry System.

http://www.epa.gov/pesticides/
                                                       A4-52

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         Final CCL 3 Chemicals:
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EPA815-R-09-006
      August 2009
Data Source Name
Identification Number
Data Source Description
Proprietor
Food Commodity Intake Database

263

The Food Commodity Intake Database (FCID) was developed as a cooperative effort by the
 United States Department of Agriculture (USDA) and OPP for use by EPA and other
organizations when conducting the exposure components of dietary risk assessments. The
FCID includes data from two surveys conducted by USDA: Continuing Survey of Food
Intakes by Individuals, and a Supplemental Children's Survey. These surveys provide
useful information on 5,831 different foods and beverages people of different ages reported
eating in 1994-96 and 1998. (FCID) is available on CD-ROM from the National Technical
Information Service (NTIS).  The product order number is PB2000-500101. (description from
website)

USDA/EPA
Contact Information


Type of Data Elements
Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
National Technical Information Service
5285 Port Royal Road, Springfield, VA22161
webmaster@ntis.gov

Unknown

This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.

It does not meet considerations because no information on type of data elements is
available.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.ntis.gov/search/results.asp?loc=3-0-0
Data Source Name
List
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Food Quality Protection Act (FQPA) - "Cumulative to Pesticides"
75

The Food Quality Protection Act requires that the Environmental Protection Agency take into
account cumulative exposure to pesticides from all sources. In accordance with this, the
EPA is in the process of reassessing tolerances for a number of pesticides. This process will
take a number of years to complete. The first pesticides to be assessed will be the
organophosphates, carbamates, and pesticides thought to be cancer-causing agents (B1 and
B2 carcinogens).  This database allows you to search by a widely-used pesticide trade name
and receive the name of the active ingredient. You can also do the reverse: enter an active
ingredient name and receive a list of common trade names. The database contains pesticide
active ingredients that are of special interest in the FQPA process.
(description from website)

EPA OPP, Cornell Pesticide Management Education Program

PMEP Staff
5123Comstock Hall
Cornell University
Ithaca, New York 14853-0901
(607)-255-1866

Name

This source is considered relevant for the CCL Universe because it contains a list of
chemicals that is related to their toxicity/health effects.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is redundant with the list of contaminants in FIFRA.

This source meets retrievability criteria because the relevant data can be extracted in tabular
format.

http://pmep.cce.cornell.edu/fapa/fgpa-list.html
                                                        A4-53

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Data Source Name
Identification Number
Data Source Description
FoodNet

74

FoodNet performs active surveillance for laboratory-confirmed cases of seven bacterial and
two parasitic organisms in limited parts of the country representing 10 percent of the U.S.
population for: Campylobacter, Salmonella, E. coli O157: H7, Listeria monocytogenes,
Shigella, Vibrio parahaemolyticus, Yersinia enterocolitica,Cyclospora cayetanensis, and
Proprietor

Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Retrievability Explanation

Source URL
Cryptosporidium parvum. For each organism, general information, technical information,
and FoodNet Publications are presented.  General information includes health effects, routes
of exposure, medical treatment, and regulations. Technical information includes
epidemiological trends.  "In active surveillance, the laboratories in the catchment areas are
contacted regularly by collaborating FoodNet investigators to collect information on all of the
laboratory-confirmed cases of diarrheal illness."  (description from website)

Produced and maintained by a collaboration of the CDC, nine Emerging Infection Program
(ElP) sites, USDA, and FDA

National Center for Infectious Diseases
Division of Bacterial and Mycotic Diseases
1600 Clifton Rd
MS
Atlanta GA 30333

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.cdc.aov/foodnet/pus.htm
Data Source Name
Identification Number
Data Source Description
Gastrointestinal Absorption Database

277

GIABS contains bibliographic citations to studies of absorption, distribution, metabolism, or
excretion of chemical substances by human or animal test subjects. Each record deals with
a specific experiment on a specific chemical as abstracted from a specific article.

SUBJECT COVERAGE :
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation
Bibliographic references
CAS Registry Numbers
Chemical name identification
Duration of test
Experimental conditions
Route of application
Species and strain of subject
(description from website)

National Information Services Corporation (NISC)/EPA

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
                                                         A4-54

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Completeness Explanation

Redundancy Explanation

Retrievability Explanation

Source URL
It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http://www.nisc.com/cis/details/giabs.htm
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
GenBank® -  National Center for Biotechnology Information

77

"GenBank® is a genetic sequence database, containing an annotated collection of all publicly
available deoxyribonucleic acid (DMA) sequences. The current collection includes
approximately 17,089,000,000 bases in 15,465,000 sequences, as of February 2002." The
coverage of the sequence records includes 5 complete bacteria, 50 retroviruses, and 39
plasm ids. (description from website)

Carnegie Mellon University; GenBank® is produced and maintained by the NCBI at NIH

National Center for Biotechnology Information
National Library of Medicine
Building 38A
Bethesda, MD 20894
Voice: (301) 496-2475
Fax:   (301)480-9241

Locus, Definition, Accession, Version, Keywords, Source, Organism, Reference, Authors,
Title, Journal, Features, Source, Gene, CDS, Variation, Genetic Sequence

This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated  retrieval.

http://www.ncbi.nlm.nih.gov/Genbank/GenbankOverview.html
Data Source Name

Identification Number
Data Source Description
Generally Regarded As Safe (GRAS) Substance List

81

The summary tables provide the following information about GRAS notices received within
each year since 1998, when FDA received its first GRAS notice:
The name of the substance
The file number (GRN No.) that FDA has assigned to the notice
A hyperlink to the letter that FDA sent in response to the notice

Within the summary table for each year, there is a hyperlink to a table that provides more
details about the GRAS notices received in that year. This includes:
The name of the notifier
The intended conditions of use

Within the detailed table for each year, there is a hyperlink to the address of the notifier.
These tables are current as of April, 2004, and therefore, does not show any new notices
filed by FDA, or response letters issued by FDA, after that date.  This table will be updated
approximately monthly, (description from website)
Proprietor
Contact Information
FDA - Center for Food Safety and Applied Nutrition

Office of Food Additive Safety (HFS-200)
Center for Food Safety and Applied Nutrition

                      A4-55

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Food And Drug Administration
5100 Paint Branch Parkway


Notifier, Intended Use, Basis, Receipt Date, Closure Date

This source is considered relevant for the CCL Universe because it contains a list of
chemicals that is related to their toxicity/health effects.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because the relevant data can be extracted in tabular
format.

http://www.cfsan.fda.aov/~rdb/opa-gras.html
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information

Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Genetic Activity Profiles (GAP) Database

76

The GAP database synthesizes around 8,000 short-term test result references on genetic
toxicity.  Coverage includes approximately 500 chemicals evaluated by International Agency
for Research in Cancer (IARC) Working Groups and published in IARC Monographs, and
over 250 EPA priority chemicals, including pesticides. Data records in GAP include "the
chemical name and CAS registry number, a test code, test endpoint, test results, highest
ineffective dose (HID) or lowest effective dose (LED), reference number, and a reference
citation".

EPA/IARC

No longer available

Chemical name, CAS registry number, test code, test endpoint, test results, highest
ineffective dose (HID) or lowest effective dose (LED), reference number, reference citation

This source is considered relevant for the CCL Universe because it contains information on
mutagenicity, which may be an indicator of potential health effects.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source has been withdrawn; it is no longer available online.

http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1568230&blobtype=pdf
Data Source Name

Identification Number

Data Source Description
Proprietor

Contact Information
GENE-TOX

78

GENE-TOX is a toxicology data file of the National Library of Medicine's (NLM) Toxicology
Data Network (TOXNET®). It is created by the U.S. Environmental Protection Agency (EPA)
and contains genetic toxicology (mutagenicity) test data, resulting from expert peer review
of the open scientific literature, on over 3000 chemicals. The GENE-TOX program was
established to select assay systems for evaluation, review data in the scientific literature,
and recommend proper testing protocols and evaluation procedures for these systems.


(description from website)

National Library of Medicine; Created by EPA; maintained by NIH's NLM

GENE-TOX Representative
National Library of Medicine
Specialized Information Services
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Fax:(301)480-3537
                      A4-56

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EPA-OGWDW
        Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Type of Data Elements

Relevance Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Telephone: (301) 496-1131
e-mail: toxmail@toxnetmail.nlm.nih.gov
URL: http://sis.nlm.nih.gov

Name, CASRN, Mutagenicity Studies, Assay Type, Evaluation Results, Panel Report,
Reference, Species/Cell Type, Species/Cell Type Sex, Taxonomic Name & Assay

This source is considered relevant for the CCL Universe because it contains information on
mutagenicity, which may be an indicator of potential health effects.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://toxnet.nlm.nih.aov/cai-bin/sis/htmlgen7GENETOX
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Genomes and Databases

79

This web site catalogs bioscience databases available on the Internet, particularly genome
databases. Multi-organism and organism-specific databases are listed.  Specific organisms
with genome data available are typical research organisms, such as mouse, Drosophila, E.
coli, and C. elegans. (description from website)

Highveld.com, a commercial guide for scientists (industry-sponsored).

Unknown

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.hiahveld.com/genome.html
Data Source Name
Identification Number
Global Infectious Disease and Epidemiology Network (GIDEON)
80
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
GIDEON is an electronic diagnostic tool that incorporates epidemiological, diagnostic, and
treatment data for 936 microbial pathogens. It can be searched by symptoms or by
microbial characteristics. Pathogen occurrence is recorded by country to facilitate
diagnosis.

GIDEON Informatics; CY Informatics

GIDEON Informatics, Inc
6010 Wilshire Blvd, Suite 302
Los Angeles, CA 90036
Toll free: (866) 699-3159
Phone: +1 (604) 699-3058
E-MAIL: info@gideononline.com
FAX:+1 (309)424-1801

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.
                     A4-57

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Retrievability Explanation

Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http://www.cvinfo.com/
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Ground Water On-Line - National Ground Water Association

82

Ground Water On-Line® is a database containing 90,331 ground water literature citations with
keywords, abstracts, chemical compounds, biological factors, geographic locations, authors,
titles, publication source names, and more. Each citation may contain up to 25 fields of
information.

Documents that are indexed include scientific, technical, and trade journals; newsletters;
books; government documents; university reports; dissertations and theses; state
publications; and proceedings of national and international conferences and symposia. The
collection is the largest and most comprehensive of its kind in the world, (description from
website)

National Ground Water Association

601 Dempsey Road
Westerville, OH 43081-8978
Phone/Toll-free 800 551.7379/ 614 898.7791
Fax/614898.7786
E-mail/ngwa@ngwa.org

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.nawa.ora/awonline/gwol.html
Data Source Name


Identification Number
Data Source Description
Guidelines for Canadian  Drinking Water Quality (CADW): Summary
of Guidelines

83

The Summary of Guidelines for Canadian Drinking Water Quality provides guidelines
(Maximum acceptable concentration (MAC), Interim maximum acceptable concentration
(IMAC), Aesthetic objectives (AO) for approximately 197 microbiological, physical/chemical
and radiological parameters that are associated with drinking water and are known, or
suspected to be harmful.

Health Canada has published Guidelines for Canadian Drinking Water Quality since 1968.
The guidelines are prepared by the Federal-Provincial-Territorial Committee on Drinking
Water. This Committee is composed of representatives from each province and territory,
as well as from Health Canada. The "Summary of Guidelines for Canadian Drinking Water
Quality" is updated and published every spring on Health Canada's website (www.hc-
sc.gc.ca/waterquality).  The most recent update was published in April 2003.

The guidelines contain authoritative information on exposure, health effects, analytical
methods, and treatment for drinking water contaminants. Coverage of the documents
includes microbiological, chemical (both organic and inorganic), physical, and radiological
issues.  Each contaminant or issue is covered in a separate guideline document, which
addresses the derivation of Maximum Allowable Concentrations (MACs) for each substance
or water quality parameter. The website states that: "These reviews are not exhaustive, but
                      A4-58

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         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Proprietor
Contact Information
Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
present a brief summary of background data and information considered to be critical for the
derivation of the guidelines." Guidelines exist for a total of over 80 water quality
parameters at this time, with more in preparation, (description from website)

Health Canada

Water Quality and Health Bureau
2720 Riverside Drive, AL 6604B
Ottawa, Ontario, K1AOK9
Fax:(613)952-2574
Email: water_eau@hc-sc.gc.ca

ADI, AO, CR, Critical Effect, DCF, Dose, Duration, Environmental Fate, Guideline,
Half-life (1/2 (days), IMAC (mg/L), LDx, MAC, NO(A)EL, Occurrence, Physical/Chemical,
Production/Use, Route

This source is considered relevant for the CCL Universe because it contains data elements
(ADI, NO(A)EL) from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.hc-sc.gc.ca/ewh-semt/alt formats/hecs-sesc/pdf/pubs/water-eau/sum guide-
res recom/summarv-sommaire-eng.pdf
Data Source Name


Identification Number
Data Source Description
Guidelines for Canadian Drinking Water Quality (CADW):
Supporting Documentation

84

The guidelines contain authoritative information on exposure, health effects, analytical
methods, and treatment for drinking water contaminants.  Coverage of the documents
includes microbiological, chemical (both organic and inorganic), physical, and radiological
issues. Each contaminant or issue is covered in a separate guideline document, which
addresses the derivation of Maximum Allowable Concentrations (MACs) for each substance
or water quality parameter. The website states  that: "These reviews are not exhaustive, but
present a brief summary of background data and information considered to be critical for the
derivation of the guidelines." Guidelines exist for a total of over 80 water quality
parameters at this time, with more in preparation, (description from website)

The Supporting Documentation is now known as Technical Documents.
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Health Canada

Water Quality and Health Bureau
2720 Riverside Drive, AL 6604B
Ottawa, Ontario, K1AOK9
Fax:(613)952-2574
Email: water_eau@hc-sc.gc.ca

Name, synonyms, formula, iMAC, MAC, IARC cancer class, ADI, MTD, LDx, NO(A)EL,

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.hc-sc.gc.ca/ewh-semt/pubs/water-eau/index-eng.phptftech doc
                                                        A4-59

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Hazardous Substances Data Bank (HSDB)

95

HSDB is a toxicology data file on the National Library of Medicine's (NLM) Toxicology Data
Network (TOXNET®). It focuses on the toxicology of potentially hazardous chemicals. It is
enhanced with information on human exposure, industrial hygiene, emergency handling
procedures, environmental fate, regulatory requirements, and related areas. All data are
referenced and derived from a core set of books, government documents, technical reports
and selected primary journal literature. HSDB is peer-reviewed by the Scientific Review
Panel (SRP), a committee of experts in the major subject areas within the data bank's scope.
 HSDB is organized into individual chemical records, and contains over 4500 such records.
(description from website)

National Library of Medicine, NIH

HSDB Representative
National Library of Medicine
Specialized Information Services
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Fax:(301)480-3537
Telephone: (301) 496-1131
e-mail: tehip@teh.nlm.nih.gov

Name, CASRN, synonyms,  ID numbers, Use, Production, IARC cancer class, EPA cancer
group, Evidence for carcinogenicity, Critical effect, Mutagenicity, Irritation data, Susceptible
populations, Body burden, Occupational exposure, MTD, LDx, Estimated daily intake, Study
data (most without specific NOAEL/LOAEL), NTP studies, Ecotox, TSCAtest submissions,
HA levels, Regulatory requirements, Federal and State DW regulations, State DW
guidelines, Molecular formula, MW, Color/form, Odor, Taste threshold, BP, MP, Critical
temperature and pressure, Density, Specific gravity, Heat of combustion, Heat of
vaporization, Log Kow, Solubilities, Spectral properties, Surface tension, Vapor density, VP,
Relative evaporation rate, Viscosity, Blood/air partition coefficient, Heat effusion, Heat

This source is considered relevant for the  CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.
Redundancy Explanation
Retrievability Explanation


Source URL
capacity, HLC    This source is not redundant.

The list of contaminants in HSDB is retrievable.  The data are not formatted for automated
retrieval. The HSDB is a  unique and exceptional source and is included to supplement the
CCL Universe.

http://toxnet.nlm.nih.aov/cai-bin/sis/htmlgen7HSDB
Data Source Name
Identification Number

Data Source Description
Proprietor
Contact Information
Health Advisories (HA) Summary Tables - EPA

87

Drinking Water and Health Advisory summary tables are prepared periodically by the U.S.
Environmental Protection Agency, Office of Water, Office of Science and Technology. They
contain drinking water standards in the form of non-enforceable concentrations of drinking
water contaminants, Maximum Contaminant Level Goals (MCLGs), or enforceable Maximum
Contaminant Levels (MCLs). Maximum Contaminant Levels are the maximum permissible
level of a contaminant in water delivered to users of a public water system. Health
Advisories (HA's) provide information on contaminants that can cause human health effects
and are known or anticipated to occur in drinking water. Health Advisories are guidance
values based on non-cancer health effects for different durations of exposure (e.g., one-
day, ten-day, and lifetime). They provide technical guidance to EPA Regional Offices, State
governments, and other public health officials on health effects, analytical methodologies,
and treatment technologies associated with drinking water contamination (taken directly from
website). The Health Advisories Summary Tables provide drinking water standards for
approximately 227 contaminants, (description from website)

EPA Office of Water; OST

SAFE DRINKING WATER HOTLINE
1-800-426-4791 or 703-285-1093
                                                         A4-60

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EPA-OGWDW
        Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Copies of the supporting technical documentation for the health advisories can be ordered
for a fee from:
Educational Resource Information Center (ERIC)
1929 Kenny Road
Columbus, OH 43210-1080
Telephone number 614-292-6717; 1-800-276-0462
FAX 614-292-0263
e-mail ERICSE@osu.edu

Name, CASRN, CR, DWA, DWEL, HA(1d, 10d, lifetime), MCL, MCLG, RfD, SDWR

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations  because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.epa.aov/ost/drinking/standards/dwstandards.pdf
Data Source Name
Identification Number
Data Source Description
Health Advisory Documents

88

The U.S. Environmental Protection Agency (EPA) has prepared Health Effects
Support Documents to assist in determining whether to establish a National Primary Drinking
Water Regulation (NPDWR) for 9 CCL contaminants. Health Advisory documents provide
information on contaminants that can cause human health effects and are known or
anticipated to occur in drinking water.
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
EPA Office of Water

SAFE DRINKING WATER HOTLINE
1-800-426-4791 or 703-285-1093
Copies of the supporting technical documentation for the health advisories can be ordered
for a fee from:
Educational Resource Information Center (ERIC)
1929 Kenny Road
Columbus, OH 43210-1080
Telephone number 614-292-6717; 1-800-276-0462
FAX 614-292-0263
e-mail ERICSE@osu.edu

Dose response assessments, Exposure from drinking water, Exposure from environmental
media other than water, Hazard identification, Physical and chemical properties, Regulatory
determination and characterization of risk, Toxicokinetics, Uses and environmental fate from
drinking water

This source is considered relevant for the CCL Universe because it contains data elements

It meets considerations  because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.epa.gov/waterscience/criteria/drinking/fchemical
Data Source Name


Identification Number
Data Source Description
Health and Safety Guides - World Health Organization, ILO, UNEP,
CCOHS
89
Health and Safety Guides (HSG) provide concise information in non-technical language, for
decision-makers on risks from exposure to chemicals, with practical advice on medical and
administrative issues.
                                                       A4-61

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Proprietor

Contact Information



Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
The Health and Safety Guide series are published by the World Health Organization for the
International Programme on Chemical Safety (a collaborative programme of the United
Nations Environment Programme, the International Labour Organisation and the World  Health
 Organization) and hard copies can be obtained from the Office of Distribution and Sales,
World Health Organization, 1211 Geneva 27, Switzerland, (description from website)

World Health Organization, International Labour Organisation, United Nations Environment
Programme, Canadian Centre for Occupational Health and Safety

The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca

CASRN, Physical/Chemical, Environmental Fate, Production/Use, Occurrence, Ecological
Toxicity, Species, Route, Dose,  Frequency, Duration, Critical Effect, CLV, ERL, MAC,
MR(es)L, MXL, RECL, STEL, TWA, LCx, LDx, LO(A)EL

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated  retrieval.
Source URL
http://www.inchem.org/paaes/hsa.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information


Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Health Effects Assessment Summary Tables (HEAST) - EPA NCEA

91

The Annual Health Effects Summary Tables (HEAST) are for use at both Superfund and
RCRA sites. It is maintained by the Environmental Protection Agencys National Center for
Environmental Assessment and provides a comprehensive listing of provisional risk
assessment information relative to oral and inhalation routes of exposure for chemicals. In
this document, slope factors are calculated by EPA to assist HEAST users with risk-related
evaluations and decision-making at various stages of the remediation process.

EPA NCEA

Dave Crawford
by phone at:  703-603-8891
or by email at: crawford.dave@epa.gov

Name, CASRN, Slope factor, Unit risk, RfD, RfC

This source is considered relevant for the CCL Universe because it contains data elements
(RfDs) from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://cfpub.epa. aov/ncea/cfm/recordisplav.cfm?deid=2877
Data Source Name
Identification Number
Data Source Description
Healthlnsite

90

Healthlnsite is an Australian Government initiative, funded by the Department of Health and
Ageing. It aims to  provide easy access to quality information about human health.  Content
is provided through information partnerships established between Healthlnsite and selected
organisations providing quality information on their websites. Organisations and websites
whose content has been proposed for access through Healthlnsite must go through the
process for the assessment of content for Healthlnsite and be approved by a highly
                     A4-62

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Proprietor
Contact Information
Type of Data Elements

Relevance Explanation
qualified editorial board. Through Healthlnsite you can find a wide range of up-to-date and
quality assessed information on important health topics such as diabetes, cancer, mental
health and asthma, (description from website)

Government of Australia

Healthlnsite Editorial Team
Online Communications Section
Department of Health and Ageing, MDP 62
GPO Box 9848
Canberra ACT 2601
Telephone: 02 6289-8488
Fax: 02 6289-3671

Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
inconsistently presented.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.healthinsite.gov.au/index.cfm
Data Source Name


Identification Number

Data Source Description
High Production Volume (HPV) Challenge Program  Robust
Summaries and Test Plans

94

The U.S. high production volume (HPV) chemicals are those which are manufactured in or
imported into the United States in amounts equal to or greater than one million pounds per
year. The U.S. HPV chemicals were identified through information collected under the Toxic
Substances Control Act (TSCA) Inventory Update Rule (IUR). Organic chemicals that are
manufactured in, or imported into, the United States in amounts equal to or exceeding 10,000
 pounds per year are subject to reporting under the TSCA IUR. Reporting is required every
four years.

The HPV Challenge Program Chemical List consists of all the HPV chemicals reported during
 the 1990 IUR reporting year. Inorganic chemicals and polymers, except in special
circumstances, were not subject to the IUR reporting requirements, although a number were
reported in error. The HPV Challenge Program Chemical List contains about 2,800 chemicals.
Proprietor
Contact Information
Type of Data Elements
The 1990 IUR list was selected as the starting point for this program. As subsequent
reporting years identify additional chemicals (including inorganics, once the corresponding
reporting requirements have been added under the IUR), they will be posted here for
information purposes. EPA expects that, over time, the testing of new HPV chemicals will
become routine, and companies may wish to test new HPV chemicals as they appear.
(description from website)

EPA

Administrator
US Environmental Protection Agency
P.O. Box 1473
Merrifield, VA22116
Attention: Chemical Rignt-to-Know Program
By Phone: (202) 564-4770

Name, CASRN, Structure, Acute Toxicity (LD50), Repeated Dose Toxicity (NOAEL, LOAEL),
 Genetic Toxicity in vitro, Genetic Toxicity in vivo, Reproductive Toxicity, Developmental
Toxicity, Acute Ecotoxicity (fish and aquatic invertebrates), Photodegradation, Stability in
Water (hydrolysis), Transport and Distribution (fugacity), Biodegradation (half-life), MP, BP,
VP, Log Kow, Water Solubility
                                                         A4-63

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Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies and environmental fate data, providing an indicator of potential

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.epa.aov/HPV/pubs/summaries/viewsrch.htm
Data Source Name
High Production Volume (HPV) Chemical List
Identification Number
Data Source Description
93

The U.S. high production volume (HPV) chemicals are those which are manufactured in or
imported into the United States in amounts equal to or greater than one million pounds per
year. The U.S. HPV chemicals were identified through information collected under the Toxic
Substances Control Act (TSCA) Inventory Update Rule (IUR).  Organic chemicals that are
manufactured in, or imported into, the United States in amounts equal to or exceeding 10,000
 pounds per year are subject to reporting under the TSCA IUR. Reporting is required every
four years.

The HPV Challenge Program Chemical List consists of all the  HPV chemicals reported during
 the 1990 IUR reporting year. Inorganic chemicals and polymers, except in special
circumstances, were not subject to the IUR reporting requirements, although a number were
reported in error. The HPV Challenge Program Chemical List contains about 2,800 chemicals.
                                   The 1990 IUR list was selected as the starting point for this program. As subsequent
                                   reporting years identify additional chemicals (including inorganics, once the corresponding
                                   reporting requirements have been added under the IUR), they will be posted here for
                                   information purposes. EPA expects that, over time, the testing of new HPV chemicals will
                                   become routine, and companies may wish to test new HPV chemicals as they appear.

                                   In keeping with that eventual goal, EPA is posting the 1994 List of HPV Additions, which
                                   contains about 500 organic HPV chemicals which were newly reported as HPV in the  1994
                                   IUR and are thus not part of the HPV Challenge Program at this time. This list is being
                                   provided particularly for use by companies who desire to propose categories of chemicals
                                   for testing and wish to include chemicals from the 1994 list in their category definitions. In
                                   some cases, companies or consortia have sponsored chemicals that are not on either the
                                   HPV Challenge Program Chemical List or the 1994 List of HPV Additions. A list of these
                                   chemicals, called "Additional Chemicals Sponsored Under the HPV Challenge Program" is
                                   also available.
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Each list contains the Chemical Abstract Services (CAS) registry number, which is a unique
identification number assigned to a chemical; an indicator variable signifying whether the
chemical falls outside the scope of the HPV Challenge Program; the chemical name; the
chemical sponsorship status; and the sponsor commitment information. The explanations of
the various values used in the indicators and status columns can be viewed under the "How
to Use the Lists" button. Searches for CAS numbers, chemical names, indicators, chemical
sponsorship status, and sponsor commitment status may be conducted using the "Search"
function. Lists may be downloaded in either Portable Data Format (PDF) or database format
(DBF), (description from website)

EPA's Office of Pollution Prevention and Toxics (OPPT)

General Contact Information for the High Production Volume Challenge Program
Administrator
US Environmental Protection Agency
P.O. Box 1473
Merrifield, VA22116
Attention: Chemical Rignt-to-Know Program
By Phone:
(202) 564-4770
chem.rtk@epa.gov

Name, CASRN, HPV Challenge status

This source is considered relevant for the CCL Universe because it is a list and contains
                      A4-64

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      August 2009
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
information on production volume, which may indicate potential occurrence.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.epa.aov/oppt/chemrtk/pubs/update/hpv 1994.htm
Data Source Name
Human Exposure Database System (HEDS)
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
92

HEDS is a web-based data system containing human exposure studies.  It is designed to
provide data sets, documents, and metadata for human exposure studies for a variety of
contaminants in several media that can be easily accessed.  HEDS allows users to download
 unanalyzed data sets for analysis, it does not provide interpretations or synthesis of
exposure data. Currently, HEDS is limited to data from the National Human Exposure
Assessment Survey (NHEXAS) program, but more studies may be available through the
system in the future,  (description from website)

EPA Office of Research and Development

Carry W. Croghan, HEDS Database Manager
U. S. Environmental Protection Agency
Human Exposure & Atmospheric Sciences Division
MD-E210C
Research Triangle Park, NC 27711
919-541-3184
Croghan.Carry@epa.gov

Contaminant Class, Sampling Method, Sampling Device, Sample Type Code, Concentration,
Qualifier, Method Det. Limit, Data Quality Flag, State, County, Samp. Location, Household
ID, Respondent #, Sample ID, Samp. Start Date, Samp. End Date

This source is considered relevant for the CCL Universe because it contains information that
 is related to potential exposure.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.

http://www.epa.gov/heds/
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information


Type of Data Elements
Idaho Toxic and Hazardous Substances - Idaho Division of Building
Safety

100

The Idaho General Safety and Health Standards have been compiled with the purpose of
consolidating all safety and occupational health standards into one book as guidelines. It is
also the intent that the safety standards contained herein be at least as effective as those
adopted by the Occupational Safety and Health Administration.

The use and exposure to toxic and to hazardous substances shall conform to all other
applicable requirements of this standard, as well as the following provisions. Nothing in this
standard shall be construed to prohibit better or otherwise safer conditions than specified
herein,  (description from website)
Idaho Division of Building Safety and Idaho Industrial Commission

1090E. Watertower St.
Meridian, ID 83642
Ph (208) 334-3950
Substance, CAS RN, Limits for air contaminants, Material, 8-hour time weighted average,

                     A4-65

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Relevance Explanation

Completeness Explanation
Acceptable ceiling concentration, Concentration, Maximum duration

This source is considered relevant for the CCL Universe because it contains inhalation
exposure limits, which may provide information on potential health effects.

It meets considerations because it meets all NDWAC minimum data requirements.
Redundancy Explanation

Retrievability Explanation
Source URL
This source is redundant with OSHA PELs (source 234), which is a more comprehensive
source.

This source meets retrievability criteria because it is in tabular format.

http://www2.state.id.us/dbs/safetv code/300.html
Data Source Name

Identification Number

Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Incidence and Prevalence Database (IPD) - Timely Data Resources

101

The Incidence and Prevalence Database provides global incidence, prevalence, morbidity,
comorbidity, cost data, symptoms and many other health issues for over 4,700 diseases
and procedures. Analysts review hundreds of medical journals, trade journals, audits, on-line
databases, registries, and market investment reports each month and summarize the data
into our Article Reviews. Full source citations are provided for each review. It also compiles
data from the most recent surveys of the National Center for Health Statistics (NCHS) in
Trend Data reports, (description from website)

Timely Data Resources, Inc.

Timely Data Resources, Inc.
107 Washburn Avenue
Capitola, CA 95010
Telephone: (408) 245-0673
Fax: (408) 245-0674
Email: support@tdrdata.com

Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.tdrdata.com
Data Source Name

Identification Number
Data Source Description
Proprietor

Contact Information
Indirect Additives Database

102

The Indirect Additives database contains administrative information (name, CAS number,
Federal Register regulation numbers, and Priority-based Assessment of Food Additives
(PAFA) database numbers) on over 3,000 substances indirectly added to foods. This list
includes substances used in food-contact articles, including adhesives and components of
coatings, paper and paperboard components, and adjuvants and production aids, (description
 paraphrased from website)

FDA - Center for Food Safety and Applied Nutrition; CFSAN, Office of Food Additive
Safety

CFSAN Outreach and Information Center
Center for Food Safety and Applied Nutrition
5100 Paint Branch Parkway (HFS-555)
College Park, MD 20740
Toll-Free Information Line:
1-888-SAFEFOOD (1-888-723-3366)
                     A4-66

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Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
CFSAN Name, CASRN, Regulation Number

This source is considered relevant for the CCL Universe because it contains a list of
chemicals that is related to potential exposure.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.cfsan.fda.aov/~dms/opa-indt.html
Data Source Name
Identification Number

Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Infectious Disease Information

103

The CDC has indexed over 500 resources concerning infectious disease, including
descriptions of viral, bacterial, and protozoan agents.  Because the summaries are from
diverse sources, they do not follow a specific format. Generally, health effects,
transmission patterns, disease prevalence, at-risk groups, and treatment are described.

CDC

Office of Health Communication
National Center for Infectious Diseases
Centers for Disease Control and Prevention
Mailstop C-14
1600 Clifton Road
Atlanta, GA 30333

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated  retrieval.

http ://www. cdc. gov/ncidod/d iseases/i ndex. htm
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Information Collection Rule (ICR) Federal Database

98

The ICR database contains research data on pathogens in drinking water sources (e.g.,
lakes, reservoirs, etc.), indicators of fecal contamination (e.g., Total Coliform, Fecal
Coliform, and E. coli), amount of disinfectant and presence of disinfection byproducts in
treated drinking water, and the effectiveness of certain treatment technologies.  Pathogens
covered include Cryptosporidium, Giardia, and viruses. Disinfection byproducts covered
include total trihalomethanes, bromate, chlorite, and haloacetic acids. Summary reports on
microbial and disinfection byproduct data at national, state, and water system levels can be
retrieved via the database. Data for the database was collected between 1997  and 1998.
(description from website)

EPA Office of Ground Water and Drinking Water

Technical Support Center:
U.S. EPA
26 Martin Luther King Drive
                                  Cincinnati, Ohio 45268
                                  Phone: 513-569-7948
                                  Fax: 513-569-7191
                                  enviromail@epamail.epa.gov
                                                        A4-67

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Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation
DBP Occurrence Concentrations

This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.

It meets considerations because it is peer reviewed.

This source is not redundant.

Data are retrievable by EPA. They may require special processing for analysis for CCL use.
Source URL
http://www.epa.gov/enviro/html/icr/index.html
Data Source Name

Identification Number
Data Source Description
Proprietor

Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retriev ability Explanation
Information System for Hazardous Organics in Water

270

ISHOW was sponsored by the Office of Toxic Substances of the US Environmental
Protection Agency. The database covers six types of physical property data for chemical
substances with bibliographic references to the original sources. Not all properties are
recorded for all substances.

SUBJECT COVERAGE:

Chemical name identification
CAS Registry Numbers
Bibliographic references
Melting point
Boiling point
Vapor pressure
Water solubility
Log partition coefficient
Acid dissociation constant
(description from website)

National Information Services Corporation (NISC)/EPA

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Name, CASRN, Bibliographic references, MP, BP, BP, Water solubility,Log partition
coefficient, Acid dissociation constant

This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.
Source URL
http://www.nisc.com/cis/details/ishow.htm
Data Source Name

Identification Number
Data Source Description
Integrated Risk Information System (IRIS)

108

IRIS is a toxicology data file on both EPAs website and on the National Library of Medicine's
 (NLM) Toxicology Data Network (TOXNET®). It contains data in support of human health
risk assessment. It is compiled by the U.S. Environmental Protection Agency (EPA) and
                                                       A4-68

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Proprietor

Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation


Retrievability Explanation


Source URL
contains over 500 chemical records. IRIS data, focusing on hazard identification and dose-
response assessment, is reviewed by work groups of EPA scientists and represents EPA
consensus. Among the key data provided in IRIS are EPA carcinogen classifications, unit
risks, slope factors, oral reference doses, and inhalation reference concentrations.

EPA Office of Research and Development; ORD, National Center for Environmental
Assessment

IRIS Representative
Specialized Information Services
National Library of Medicine
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Fax:(301)480-3537
Telephone: (301) 496-1131
e-mail: toxmail@toxnetmail.nlm.nih.gov
IRIS
c/o ASRC
6301 Ivy Lane, Suite 300
Greenbelt, MD 20770
U.S. EPA Risk Information Hotline at telephone 1-301-345-2870, or fax to 1-301-345-2876, or
email to Hotline.IRIS@epamail.epa.gov

Name, Synonyms, CASRN, RfC, RfD, SF(i,o), UR(i,o), NO(A)EL, LO(A)EL, BMC/D, BMDL,
Critical effect

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets all considerations because it is peer reviewed.

The toxicological data for this source are available in tabular format from ITER (#110) and
RAIS-Health Effects (#178). Hence there is some overlap and redundancy, but each also
provide additional information not available elsewhere.

This source contains monographs that were not formatted for automated retrieval. However,
the toxicological data from this source have been compiled for electronic retrieval in ITER,
and were obtained from there. IRIS monographs were used to confirm the IRIS/ITER data.

http://www.epa.gov/iris/index.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Integrated Taxonomy Information System

104

ITIS is a collaboration among the U.S., Mexican and Canadian governments, and nonprofit
partner organizations, to create a comprehensive and consistent taxonomic catalog. An
interesting feature is the reference to experts for particular organisms. The Taxonomic
Resources and Expertise Directory (TRED) is searchable by expert or organism.

Partnership based at the USDA

Dr. Michael Ruggiero, Director
Integrated Taxonomic Information System (IT IS)
c/o Smithsonian Institution/NMNH MRC - 0180
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retriev ability Explanation
Source URL
Washington, DC 20560-0180
Phone:202-786-3117
fax: 202-786-2934
ruggiero.michael@nmnh.si.edu

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.itis.usda.gov/index.html
                                                        A4-69

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Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
International Agency for Research on Cancer (IARC) - Summaries
and Evaluations

204

In 1969, the International Agency for Research on Cancer (IARC) initiated a programme on
the evaluation of the carcinogenic risk of chemicals to humans involving the production of
critically evaluated monographs on individual chemicals. In 1980 and 1986, the programme
was expanded to include evaluations of carcinogenic risks associated with exposures to
complex mixtures and other agents.

The objective of the programme is to elaborate and publish in the form of monographs
critical reviews of data on carcinogenicity for agents to which humans are known to be
exposed and on specific exposure situations; to evaluate these data in terms of human risk
with the help of international working groups of experts in chemical carcinogenesis and
related fields; and to indicate where additional research efforts are needed,  (description from
website)

International Agency for Research on Cancer

The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca

Name, CASRN,  IARC Cancer Class

This source is considered relevant for the CCL Universe because it contains data elements
directly from and derived from toxicological studies.

It meets considerations because it is peer reviewed.

This source is redundant, as it is wholly available as part of INTOX (source 105).

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.inchem.org/paaes/iarc.html
Data Source Name
Identification Number
International Agency for Research on Cancer (IARC) Monographs
96
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
The IARC "publishes authoritative independent assessments by international experts of the
carcinogenic risks posed to humans by a variety of agents, mixtures and exposures."  In the
first 75 volumes of this monograph series, 839 agents have been evaluated. Each
monograph consists of a brief description, where appropriate, of the potential exposure to the
agent or mixture, by providing data on chemical and physical properties, methods of
analysis, methods and volumes of production, use and occurrence. For exposure
circumstances, a history and description of the exposure are given. Then, the relevant
epidemiological studies are summarized.  Subsequent sections cover evidence for
carcinogenicity obtained in experimental animals, and a brief description of other relevant
data, such as toxicity and genetic effects,  (description from website)

International Agency for Research on Cancer

lARCPress
WHO-IARC Office
1775 K Street NW, Suite 480
Washington DC, 20006, USA
Fax: + 1 2022231782;
E-mail: IARC Press (iarcpress@who.int)

Summary of Data Reported and Evaluation, Exposure data, Human carcinogenicity data,
Animal carcinogenicity data, Other relevant data, Overall evaluation, Previous evaluations

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.
                                                        A4-70

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      August 2009
Retrievability Explanation
Source URL
The monographic information in this source is not retrievable; however, the list of
contaminants and their cancer groups is retrievable and will be used for the CCL Universe.
IARC is a unique and exceptional source and is included to supplement the CCL Universe.

http://www-cie.iarc.fr/monoeval/grlist.html
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation
International Bibliographic Information on Dietary Supplements
(IBIDS)-NIH

97

The International Bibliographic Information on Dietary Supplements (IBIDS) database
provides access to bibliographic citations and abstracts from published, international,
scientific literature on dietary supplements. The Office of Dietary Supplements (ODS) at the
 National Institutes of Health produces this database to help consumers, health care
providers, educators, and researchers find credible, scientific information on a variety of
dietary supplements including vitamins, minerals and botanicals. IBIDS was developed and
is maintained through an interagency partnership with the Food and Nutrition  Information
Center, National Agricultural Library, U.S. Department of Agriculture, (description from
website)

National Institutes of Health

Office of Dietary Supplements
National Institutes of Health
6100 Executive Blvd., Room 3B01, MSC 7517
Bethesda, Maryland  20892-7517
Tel: (301) 435-2920
Fax: (301)480-1845
E-mail: ods@nih.gov

Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
Completeness Explanation
Redundancy Explanation
Retriev ability Explanation

Source URL
It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://ods.od.nih.gov/databases/ibids.html
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
International Chemical  Safety Cards (ICSCs) - IPCS/WHO/ILO

99

"An ICSC summarizes essential health and safety information on chemicals for their use at
the "shop floor" level by workers and employers in factories, agriculture, construction and
other workplaces." Available for over 100 chemicals, ICSCs consist of a series of standard
categories, including acute hazards/symptoms, routes of exposure, and physical properties.
 (description from website)

International Programme for Chemical Safety, World Health Organization

Centers for Disease Control and Prevention
1600 Clifton Rd
Atlanta, GA 30333, USA
Phone: 1-800-35-NIOSH (1-800-356-4674)
Fax: 1-513-533-8573

Types of hazard/exposure, Acute hazards/ symptoms, Spillage disposal, Storage, Packaging
and Labelling,  Prevention, First aid/ Fire fighting, Molecular Mass, Chemical formula,
Synonyms, Routes of Exposure, Physical Dangers, Inhalation Risk, Chemical Dangers,
Effects of Short-term Exposure, Effects of Long-term Exposure or repeated exposure,

                      A4-71

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EPA815-R-09-006
      August 2009
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Occupational exposure limits, Melting point, Density, Solubility, Vapor pressure, Log Kow,

This source is considered relevant for the CCL Universe because it contains inhalation
exposure limits, which may provide information on potential health effects.

It meets considerations because it is peer reviewed.

This source is redundant, as it is wholly available as part of INTOX (source 105).

This source does not meet  retrievability criteria because the data are not formatted for
automated retrieval.

http://www.cdc.aov/niosh/ipcs/nicstart.html
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
International Cosmetic Legal and Regulatory Database - The
Cosmetic, Toiletry, and Fragrance Association (CTFA)

43

According to the web site, "the database is comprised of basic health laws, cosmetic
regulations, and other government rules governing cosmetic products for over 60 countries.
It also has a separate ingredient database which compares ingredient restrictions and use
requirements for all covered countries."

Cosmetic, Toiletry, and Fragrance Association

The Cosmetic, Toiletry, and Fragrance Association
1101 17th Street, NW, Suite 300
Washington D.C. 20036-4702
telephone: (202) 331-1770
fax:(202)331-1969
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation

Retrievability Explanation

Source URL
Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.ctfa-international.org/brochure.htm
Data Source Name

Identification Number

Data Source Description
Proprietor
Contact Information
Type of Data Elements
International Pharmaceutical Abstracts (IPA)

106

IPA includes bibliographic information covering pharmaceutical and health-related literature.
Literature coverage includes over 750 pharmaceutical, medical, and health-related journals
published since 1970. Specific topics include adverse drug reactions and toxicity,
pharmaceutics, drug evaluations and interactions, drug metabolism and body distribution,
drug stability, environmental toxicity, and related health topics.

Silver Platter; American Society of Health-System Pharmacists

333 Seventh Avenue
20th Floor
New York, NY 10001
Telephone: 646-674-6300
Toll Free in US: (800)-950-2035
Fax: 646-674-6301
E-mail: sales@ovid.com

Bibliographic information, Indexing terms, Abstracts, Chemical  names, and CAS Registry
Numbers
                     A4-72

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EPA815-R-09-006
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Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.ovid. com/sit e/cataloq/DataBase/109. isp?top=2&mid=3&bottom=7&subsection=10
Data Source Name


Identification Number
Data Source Description
International Register of Potentially Toxic Chemicals (IRPTC PC)
Data Profiles - UNEP Chemicals

109

United Nations Environment Programme (UNEP) Chemicals is the center for all chemicals-
related activities of the United Nations Environment Programme. This database contains
profiles for approximately 8,000 individual chemicals. It covers a complete range of the
physico-chemical properties and major endpoints such as environmental fate, mammalian
Proprietor

Contact Information
Type of Data Elements
Relevance Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
toxicity, ecotoxicity, evaluations from national and international peer reviewed sources, and
legislation.
(description from website)

United Nations Environment Programme; UNEP, Division of Technology, Industry, and
Economics

James B. Willis, Director
UNEP Chemicals (IRPTC)
Chemin des Anemones
Case postale 365, CH-1219 Chatelaine
Geneva, Switzerland
Tel.:+41-22-979-9111
Fax:+41-22-797-3460
E-mail: irptc@unep.ch
www: http://irptc.unep.ch/irptc

Environmental fate, Production, Mammalian Toxicity

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies and environmental fate data, providing an indicator of potential

This source is not redundant.

This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.

http://www-caer.nies.ao.ip/cqer-e/db/info-e/lnfoDBWeb/db/irptc.htm
Data Source Name
Identification Number
Data Source Description
International Toxicity Estimates for Risk (ITER) Database

110

ITER is a free Internet database of human health risk values for over 600 chemicals of
environmental concern from several organizations worldwide. ITER is the only database that
provides this data in a table format that allows side-by-side comparisons of risk values from
different organizations. Below the table is a synopsis that includes an explanation for any
differences among the organizations' values. ITER provides links to these organizations for
more detailed information. ITER currently contains data from:

Agency for Toxic Substances and Disease Registry (ATSDR)
ATSDR derives minimal risk levels (MRLs), which are found in the Agency's Toxicological
Profiles. Nearly all of the data from ATSDR's Toxicological Profiles are now on ITER; the
remaining ATSDR sections are flagged to indicate that the data are being prepared.

Health Canada
Health Canada develops Tolerable Intakes/Concentrations and Tumorigenic
                     A4-73

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      August 2009
                                    Doses/Concentrations for Priority Substances under the Canadian Environmental Protection
                                    Act (CEPA). These risk values for Health Canada are included on ITER.

                                    International Agency for Research on Cancer (IARC)
                                    IARC evaluates the cancer weight of evidence for chemicals over a wide range of human
                                    exposures and classifies chemicals according to potential for carcinogenicity. The results of
                                    IARC analyses are published Monographs. lARC's cancer classification categories refer only
                                    to the strength of the evidence that an exposure is carcinogenic and not to the extent of its
                                    carcinogenic activity (potency) nor to the mechanisms involved.

                                    National Institute of Public Health and the Environment (RIVM), The Netherlands
                                    RIVM develops human-toxicological risk limits (i.e., maximum permissible risk levels, MPRs)
                                    for a variety of chemicals based on chemical assessments that are compiled in the
                                    framework of the Dutch government program on risks in relation to soil quality. The MPRs
                                    updated in 2001 are currently being added to ITER.

                                    U.S. Environmental Protection Agency (EPA)
                                    EPA derives risk values called reference concentrations (RfCs), reference doses (RfDs)
                                    and cancer assessments. All of these risk values from EPA's Integrated Risk Information
                                    System (IRIS) are included on ITER.
Proprietor

Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation
Source URL
Independent parties whose risk values have undergone peer review
Risk values developed by other parties (e.g. industry, consulting groups, or universities) are
included on ITER (under the ITER column) after they have undergone an independent peer
review (http://www.tera.org/peer). This independent peer review is typically convened by
TERA through its Peer Review Program, and if the expert panel concurs with an assessment,
 it may be made available to the public on the ITER database.  Over two-dozen independent
risk values have been included on ITER, and are compared with the risk values from other
organizations. These independent values can only be found on ITER. (description from
website) ITER is also available from NLM as part of its TOXNET suite of databases.

TERA - Toxicology Excellence for Risk Assessment / NLM

1757 Chase Avenue
Cincinnati OH 45223
Phone: 513-542-7475
Fax: 513-542-7487
Email: TERA@TERA.org orwullenweber@tera.org

Name, CASRN, Critical effect, Cancer risk, Slope factor, MRL,  RfD, RfC, TC(A), TDI,
RSC, RSD, LO(A)EL, NO(A)EL,  TumCx, TumDx, TC05, TC01, TD05, Tl, TC, Risk Value,

This source is considered relevant for the CCL Universe because it contains data  elements
directly from and derived from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.tera.org/iter
Data Source Name

Identification Number
Data Source Description
INTOX Databank - IPCS

105

The IPCS INTOX Package is a computerized poisons information package which is designed
to assist poison centres, health ministries and other related institutions to develop and
strengthen their capabilities for the efficient management of information relating to
poisoning,  national product registration and chemical incidents.

The IPCS INTOX Package consists of the IPCS INTOX Data Management System and the
IPCS INTOX Databank. The Data Management System is a poisons information database
management software system, whilst the Databank is a collection of documents on
poisonous  substances. Together they provide information on industrial chemicals,
Pharmaceuticals, household  products, agricultural chemicals and plant, fungal and animal
toxins, as well as other agents commonly responsible for poisoning. This global, multilingual
package provides information on poisons and facilitates the management of information and
communication between poison information centres and inquirers.
(description from website)
                      A4-74

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Proprietor
Contact Information
Type of Data Elements
IPCS

Canadian Centre for Occupational Health and Safety
135 Hunter Street East
Hamilton, ON, Canada L8N 1M5
1-800-668-4284

Contains EHC monographs, ICSCs, PIMs, and IARC Summaries and Evaluations, Pesticide
Data Sheets. Data elements in CHEMINFO files: Name, Synonyms, CASRN, other IDs,
Molecular formula, Structure, Appearance and odor, Odor threshold, Uses, Flash point, Lower
and upper flammable and explosive limits, Autoignition temperature, Sensitivity to
mechanical impact and static charge,  MW, MP, BP, Relative density (specific gravity),
Water solubility, Other solubilities, Partition coefficient, pH value, Vapor density, VP,
Saturation vapor concentration, Evaporation rate, Critical temperature, Critical pressure,
Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
Viscosity, Surface tension, LC/LDx, Short- and long-term effects, Carcinogenicity,
Mutagenicity, Teratogenicity/embryotoxicity, Reproductive tox

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is redundant with IARC - Summaries and Evaluations.  INTOX is a subscription
source and IARC is independently and publicly available.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http://www.intox.org
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
IPCS/EC Evaluation of Antidote Series

107

The IPCS/EC Evaluation of Antidotes Series Provides definitive and authoritative guidance
on the use of antidotes to treat poisoning. The International Programme on Chemical Safety
(IPCS) and the Commission of the European Union (EC) are jointly undertaking a major
project to evaluate antidotes used clinically in the treatment of poisoning. The aim of this
project is to identify and evaluate for the first time in a scientific and rigorous way the
efficacy and use of a wide range of antidotes. This series summarises and assesses, on an
antidote-by-antidote basis, their clinical use, mode of action and efficacy. The aim is to
provide an authoritative consensus statement which will greatly assist in the selection and
administration of an  appropriate antidote. This scientific assessment is complemented by
detailed clinical information on routes of administration, centra-indications and precautions.
The series collates a wealth of useful  information which will be of immense practical use to
clinical toxicologists  and all those involved in the treatment and management of poisoning.
(description from website)

International Programme for Chemical Safety, Commission of the European Union

The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment  Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca

Field, Introduction, Name and chemical formula, Physico-chemical properties,
Pharmaceutical formulation and synthesis, Analytical methods, Shelf life, General
properties, Animal studies, Toxicology, Volunteer studies, Pharmacodynamics,
Pharmacokinetics, Clinical studies - clinical trials, Clinical studies - case reports, Route of
administration, Summary of evaluation and recommendations, Model information sheet,
References, Historical review, Summary of analytical aspects, References, Mechanism of
toxicity, Laboratory findings, Treatment, Qualitative methods, Quantitative methods

This source is considered relevant for the CCL Universe because it contains data elements
from  toxicological studies.

It meets considerations because it is peer reviewed.

This source is redundant, as it is wholly available as part of INTOX (source 105).

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
                                                          A4-75

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         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Source URL
http://www.inchem.org/paaes/antidote.html
Data Source Name
Joint Expert Committee on Food Additives (JECFA) - Monographs
and Evaluations
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
111

Toxicological evaluations of food additives and contaminants and of residues of veterinary
drugs in food, produced by the Joint WHO/FAO Expert Committee on Food Additives
JECFA, are used by the Codex Alimentarius Commission and national governments to set
international food standards and safe levels for protection of the consumer. The monographs
 provide the toxicological information upon which the JECFA makes its evaluations. These
monographs are prepared by scientific experts and peer reviewed at the JECFA meetings.
(description from website)

World Health Organization, Food and Agriculture Organization

The International  Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca

Summary of evaluations, Recommended dietary allowance, Carcinogenicity,  Mutagenicity,
Reproduction, Teratogenicity, Acute Toxicity,  Short term studies, Long-term studies,
Observations in humans, Immune response, Ototoxicity, Microbiological effects

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.who.int/ipcs/publications/iecfa/monographs/en/
Data Source Name


Identification Number

Data Source Description
Proprietor
Contact Information
Joint Meeting On Pesticide Residues (JMPR) - 2001 Inventory of
Pesticide Evaluations

112

This inventory summarizes evaluations of pesticides that have been performed by the Joint
FAO/WHO Meeting on Pesticide Residues (JMPR) and other assessments of pesticides by
IPCS and other programmes in WHO. It does not include the maximum residue limits (MRLs)
that have been recommended by JMPR.

The inventory itself lists relevant documents that have been published and summarizes the
acceptable daily intakes (ADIs) and provisional tolerable daily intakes (PTDIs) that have
been established by JMPR. It should be noted that the first entry under each pesticide is the
one that is currently applicable. JMPR has not evaluated those pesticides that do not
include the JMPR evaluations heading.

Annex 1 defines the codes and explains the abbreviations used in Table 1 and Annex 2,
which includes links to documents that are available electronically, lists the reports and other
documents resulting from the Joint Meetings on Pesticide Residues that have been held to
date. Many of the older publications that are listed are out of print but are available
electronically. Addresses for obtaining documents and publications are provided in Annex  1.
Annex 3 provides further information on several specific pesticides that are referenced in
the inventory, (description from website)

World Health Organization, Food and Agriculture Organization

The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca
                                                        A4-76

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        Final CCL 3 Chemicals:
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EPA815-R-09-006
      August 2009
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Name, CASRN, ADI
This source is considered relevant for the CCL Universe because it contains data elements
derived from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.who.int/ipcs/publications/impr/en/
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Joint Meeting On Pesticide Residues (JMPR) - Monographs of
Toxicological Endpoints
113
Toxicological evaluations of pesticides, produced by the WHO/FAO Joint Meeting on
Pesticide Residues JMPR , are used by the Codex Alimentarius Commission and national
governments to set international food standards and safe levels for protection of the
consumer. The monographs provide the toxicological information upon which the JMPR
makes its evaluations. These monographs are prepared by scientific experts and peer
reviewed at the JMPR meetings, (description from website)
World Health Organization, Food and Agriculture Organization
The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca
Name, CASRN, Formula, Structure, ADI, RfD, DWGLs, pTDI, RfD, LDx, NO(A)EL,
LO(A)EL
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
http://www.inchem.ora/pages/impr.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Label Review Manual
264
The Label Review Manual was developed as a training tool and guidance for reviews of
pesticide product labels. The goals are to improve the quality of labels and increase the
consistency of reviews. The manual describes what a pesticide is and what constitutes a
label and labeling and also provides step-by-step instructions for reviewing a pesticide label
and how unique issues have been handled in the past, (description from website)
EPA, OPP
Office of Pesticide Programs at 703-308-9068
General Labeling Requirements, Types of Label Review, Ingredient Statement, Use
Classification, Precautionary Labeling, Environmental Hazards, Physical or Chemical
Relevance Explanation
Completeness Explanation
Hazards, Worker Protection Labeling, Directions for Use, Labeling Claims, Storage and
This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.
It meets considerations because it meets all NDWAC minimum data requirements.
                     A4-77

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         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Redundancy Explanation
Retrievability Explanation

Source URL
This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.epa.aov/oppfead1/labeling/lrm/
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
Laboratory Chemical Safety Summaries (LCSS) - Howard Hughes
Medical Institute and National Academy of Science

114

The Howard Hughes Medical Institute collaborated with the National Academy of Sciences in
making the 88 Laboratory Chemical Safety Summaries (LCSSs) prepared by the National
Research Council, Committee on Prudent Practices for Handling, Storage, and Disposal of
Chemicals in Laboratories.

The LCSSs provide concise critical discussions of the toxicity, flammability, reactivity, and
explosibility of 88 chemicals commonly used in scientific research laboratories. Directions
for handling, storage, and disposal and special instructions for first aid and emergency
response are given. Since many of these 88 chemicals are representative of a class of
potentially hazardous compounds, the LCSSs can also be used as guides to handling many
other compounds with related chemical structures. The LCSSs are designed especially for
laboratory workers, (description from website)

Howard Hughes Medical Institute, National Academy of Science

Howard Hughes Medical Institute
4000 Jones Bridge Road
Chevy Chase, MD 20815-6789
(301)215-8500
E-mail: webmaster@hhmi.org

Substance, Formula, Physical Properties, Odor, Vapor Density, Vapor Pressure, Flash Point,
Autoignition Temperature, Toxicity Data, Major Hazards, Toxicity, Flammability and
Explosibility, Reactivity and Incompatibility, Storage and Handling, Accidents, Disposal

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data  are not formatted for
automated retrieval.


http://dwb4.unl.edu/Chem/CHEM869V/CHEM869VLinks/www.qrc.com/hhmi/science/labsafe/lcss/sta
rt. htm
Data Source Name

Identification Number
Data Source Description
List of Bacterial Names with Standing in Nomenclature

115

The Society for Systematic and Veterinary Bacteriology in France maintains an up-to-date
online list of approved bacterial nomenclature.  This source provides an alphabetically and
chronologically list of the nomenclature of bacteria as cited in the Approved Lists of
Proprietor

Contact Information
Bacterial Names, or validly published in the International Journal of Systematic Bacteriology
and in the International Journal of Systematic and Evolutionary Microbiology.

Society for Systematic and Veterinary Bacteriology

J. Euzeby
Laboratoire de Bacteriologie
Ecole Nationale Veterinaire
23, chemin des Capelles
B.P. 87614
31076, Toulouse cedex 03, France

                      A4-78

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      August 2009
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
Fax:+33 5 61 193975
E-mail: J.P. Euzeby

Genera and taxa above the rank of genus up to and including class, Type species,
Reference, Original article in IJSEM Online, Note, List of Candidatus, Taxa above the rank
of class, All validly published names, Culture collections of prokaryotes, Some bacterial
names without standing in nomenclature, Definitions and abbreviations

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.bacterio.cict.fr/index.html
Data Source Name
Identification Number

Data Source Description
Proprietor
Contact Information
Mallinckrodt Baker, Inc., Material Safety Data Sheets

286

MALLIN is a collection of approximately 1,975 material safety data sheets prepared by by
Mallinckrodt Baker, Inc., of St. Louis, Missouri, and Phillipsburg, NJ, in accordance with
guidelines issued by the US Occupational Safety and Health Administration (OSHA). One
chemical substance is covered in each record.

SUBJECT COVERAGE :

Chemical  identification
Regulations
Health and fire hazards
Physical property data
Reactivity data
Spill and  disposal procedures
CAS Registry Numbers
Protective equipment
First aid information
Storage and handling data
(description from website)

National Information Services Corporation (NISC)

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1  410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com
Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Availability of Treatment, Health Effects, PEL, Infectious Dose, Mortality,
Physical/Chemical Properties, Toxicological Information, Reproductive Toxicity,

This source is considered relevant for the CCL Universe because it contains environmental
fate data, that may be used as an indicator of potential occurrence.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http://www.nisc.com/cis/details/mallin.htm
                                                         A4-79

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EPA-OGWDW
                                          Final CCL 3 Chemicals:
                                          Identifying the Universe
EPA815-R-09-006
      August 2009
Data Source Name


Identification Number
Data Source Description
                                 Master Summary Table for HPV Chemical Hazard Data Availability
                                 Study
                                 116

                                 The Master Summary Table for the US High Production Volume (HPV) Chemical Hazard Data
                                  Availability Study contains information on whether or not data on six hazard endpoints are
                                 publicly available for 2863 US HPV organic chemicals (68 inorganic HPV chemicals were
                                 deleted from the original database of 2931 HPV chemicals reported under the 1990 Inventory
                                  Update Rule). The six hazard endpoints (acute toxicity, chronic toxicity, teratogenicity or
                                 developmental and reproductive toxicity, mutagenicity, ecotoxicity,  and environmental fate)
                                 comprise the "Screening Information Data Set" (SIDS) test battery established by the
                                 Organization for Economic Cooperation and Development (OECD, 1998a).

                                 Variable names for each column are shown in the first row of the database. The remaining
                                 rows contain the information on hazard data availability for the chemicals. The first column
                                 (CAS.NO) contains the Chemical Abstract Services registry number, which is a unique
identification number assigned to a chemical. The name of the chemical is displayed in the
                                 second column (CHEMICAL). An "X" is shown in the third column (ACUTE), if EPA was able
                                 to locate any information on acute toxicity testing. Columns 4 (CHRONIC), 5 (TERARE), 6
                                 (MUTAGEN), 7 (ECOTOX), and 8 (FATE) are also marked with an "X" if hazard data were
                                 located for chronic toxicity, teratogenicity or developmental/reproductive toxicity,
                                 mutagenicity, ecotoxicity, and environmental fate, respectively. The total number of six
                                 hazard test data endpoints located for each chemical is shown in Column 10 (TOTAL).

                                 Some 277  of the 2863 US HPV chemicals are part of the ongoing OECD SIDS international
                                 program. Some of the SIDS testing is complete, but many of those studies have not yet
                                 been entered into publicly accessible databases, although all of the information will be
                                 available in the future as those databases are updated. A "C" or "U" is marked in Column 9
                                 (SIDS) if the chemical is part of the OECD SIDS testing program. A"C" indicates that
                                 testing has been completed, and a "U" denotes that testing is ongoing. Copies of completed
                                 SIDS dossiers are available through the United Nations Environmental Programme (UNEP,
                                 1996). The Master Summary Table will be updated to include the SIDS information once the
                                 hazard data become available.

                                 Additional columns in the table indicate whether the chemical is a high release TRI chemical
                                 (TRI  HIGH), whether the chemical is on the 1995 TRI database (TRI), whether an OSHA PEL
                                 (OSHA PEL) is in place for the chemical, and whether the chemical is a consumer  product
                                 chemical (CPC) listed in EPA's Source Ranking Database, (description from website)
Proprietor
Contact Information
                                 EPA, OPPT

                                 US Environmental Protection Agency
                                 Chemical Information and Testing Branch
                                 1200 Pennsylvania Avenue, NW
                                 Mail Code 7405M
                                 Washington, DC 20460
                                 202-564-4780
                                 Fax: 202-564-4765
                                 E-mail: ccd.citb@epa.gov
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation
Source URL
                                 Name, CASRN, SIDS and TRI status, Availability of toxicity data

                                 This source is considered relevant for the CCL Universe because it contains a list that is
                                 related to occurrence.

                                 It meets considerations because it meets all NDWAC minimum data requirements.

                                 This source is redundant, as it is wholly available as part of the HPV Chemical List (source
                                 93) and CUS/IUR (source 33).

                                 This source meets retrievability criteria because it is in tabular format.

                                 http://www.epa.aov/opptintr/chemtest/hazchem.htm
Data Source Name
Identification Number
Data Source Description
                                 Material Safety Data Sheets (MSDS)

                                 124

                                 Material Safety Data Sheets for more than 200 infectious agents have been produced. The
                                 type of information provided and technical  language used are geared toward laboratory
                                                       A4-80

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Proprietor
Contact Information
Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
personnel. Basic disease descriptions, infective doses, and decontamination procedures are
described.

Health Canada

Health Canada
A.L. 0900C2
Ottawa, Canada
K1AOK9
Telephone: (613) 957-2991
Fax:(613)941-5366
TTY: 1-800-267-1245
wm-pphb-dgspsp@hc-sc.gc.ca

Name, Synonym, Characteristics, Pathogenicity, Epidemiology, Host range, Infectious
Dose, Mode of transmission, Incubation period, Communicability, Reservoir, Zoonosis,
Vectors, Drug susceptibility, Drug resistance. Survival outside host

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.hc-sc.ac.ca/pphb-dgspsp/msds-ftss/
Data Source Name
Identification Number
Data Source Description


Proprietor
Contact Information
Type of Data Elements
Mediscover

117

Mediscover provides medical news and information concerning emerging diseases and
treatments. Although the site presents news concerning infectious diseases in general, its
focus is on vaccines.

International Medical Press

info@mediscover.net

Data elements for microbial contaminants
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.mediscover.net
Data Source Name
Identification Number
Data Source Description
MEDLINE

278

Medline is the electronic version of Index medicus, a comprehensive index of scientific
periodical literature in the medical sciences compiled by the National Library of Medicine. It
includes all medically related areas of biology and all medical specialties, and is particularly
strong in molecular biology.

Medline indexes journal articles and chapters in symposia, not whole books, including more
than 3800 journals and other periodical publications. Medline covers the literature from 1966.
Most current articles have abstracts. Coverage is worldwide, but most items are in English or
have English abstracts. There is systematic indexing for standardized medical vocabulary,
and extensive use of acronyms, enzymes, gene names, and names of key reagents.
                                                         A4-81

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
The CIS subset of NIOSHTIC® records are required to provide a CAS Registry Number and
discuss one or more of the following subjects: Hazmat, Biodegradation, Environmental Fate,
Gastrointestinal Absorption, Toxicity, Carcinogenicity, Turmorigenicity, Mutagenicity,
Teratogenicity, Acid Dissociation, Bioconcentration Factor, Effluent Concentrations,
Photooxidation, Ultraviolet Absorption, Volatilization, Superfund Sites, or Occupational
Safety, (description from website)

National Information Services Corporation (NISC)

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria  because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.nisc.com/cis/details/medline.htm
Data Source Name
Identification Number
Michigan State Ribosomal Database Project
118
Data Source Description


Proprietor

Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This database catalogs over 30,000 ribosomal ribonucleic acid (rRNA) sequences from
diverse organisms, including pathogens, because such sequences are conserved and can be
 used to determine phylogenetic relationships.

Michigan State University researchers (funded by the National Science Foundation (NSF)
and DOE)

Ribosomal Database Project
2225A Biomedical and Physical Sciences Building
Michigan State University
East Lansing, Ml, 48824
(517) 432-4998 (phone)
(517) 353-8957 (Microbiology Dept fax)
e-mail: rdpstaff@msu.edu

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://rdp.cme.msu.edu/html/index.html
Data Source Name
Identification Number
Data Source Description
MicrobeLibrary

119

MicrobeLibrary is a catalogued collection of peer reviewed teaching resources related to
microbial biology.  Four groups of resources are available: visual, curriculum, articles, and
                      A4-82

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Proprietor

Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
reviews. The MicrobeLibrary is searchable portal providing a peer reviewed, web-based
collection of resources about the microbial world. The Library builds upon the scientific
expertise, intellectual creativity, and private collections of the 42,000 members of the
American Society for Microbiology (ASM) and other microbial researchers from around the
world, (description from website)

American Society for Microbiology (funded by NSF)

ASM's MicrobeLibrary
Education Department
1752 N Street N.W.
Washington, DC 20036
Phone: 202-942-9282
Fax: 202-942-9329
MicrobeLibrary@asmusa.org

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.microbelibrarv.org/
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation


Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
Microbiology Abstracts, Section B:  Bacteriology - Cambridge
Scientific Abstracts

120

The well-rounded, medically-oriented coverage in Bacteriology makes it possible for
researchers and clinicians to keep up with the constant changes in this explosive field. With
topics ranging from bacterial immunology and vaccinations to diseases of man and animals,
the journal provides access to far-reaching clinical findings as well as all aspects of pure
bacteriology, biochemistry, and genetics. General microbiologists and bacteriologists aren't
the only specialists who turn to Bacteriology each month for important perspectives in the
field. The journal is also valuable to environmentalists, medical and veterinary laboratory
staff, agricultural researchers, cell biologists, geneticists, toxicologists, and many others.
Major areas of coverage include: Aggressins and toxins, Animal  bacteriology, Antibacterial
agents, Antibiosis, Antibiotics, Cell structure and function,  Culture
Ecology and distribution, Genetics and evolution, Human bacteriology, Identification,
Immunology, Invetebrate bacteriology, Methodology, Microbial symbiosis, Plasmids,
Predation, Taxonomy, Typing,  (description from website)

Cambridge Scientific Abstracts

Cambridge Scientific Abstracts
7200 Wisconsin Avenue
Bethesda, MD 20814 USA
Voice: 800-843-7751  (in N. America)
Voice: +1 301-961-6700 (worldwide)
Fax:+1 301-961-6720
Email: sales@csa.com

Bibliographic information, Indexing terms, Abstracts

This source does not  meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations  because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not  meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.csa.com/csa/ids/databases-collections.shtml - environmental
                                                          A4-83

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
MicrobioNet

121

Microbionet is an Australian tor-profit corporation providing comprehensive information by
genus or by species for bacteria and, in the future, for viruses and protozoa. Available free
online are pathogen profiles that include classification, biochemistry, serology, genetics,
virulence factors, normal flora, pathogenicity, laboratory ID, and environmental, industrial,
and vaccine data. More comprehensive reviews are slated to become available to paying
members (this feature is currently under construction).

Sciencenet Multimedia Publishing House; Microbionet

Sciencenet Multimedia Publishing House Pty Limited
CAN 074 869 122
40 Hastings Road Hawthorn East, 3123, Victoria Australia
Attention: Barbara Wagstaff Chief Executive Officer
Tel: +61-3-9882-2665
Fax:+61-3-9882-6811
email: bmwag@planet.net.au
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Classification, Biochemistry, Genetics, Serology, Virulence Factors, Normal Flora,
Pathogens, Laboratory Diganosis of Infections, Environmental Aspects, Industial Uses,

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.sciencenet.com.au/index.html
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Morbidity and Mortality Weekly Report (MMWR) Surveillance for
Waterborne-Disease Outbreaks

122

EPA and the CDC have maintained a collaborative surveillance system for collecting and
periodically reporting data that relate to occurrences and causes of waterborne-disease
outbreaks. The surveillance system includes data about outbreaks associated with both
drinking water and recreational water.  Surveillance summaries are based on State, territorial,
and local public health department reporting of waterborne-disease outbreaks,  (description
from website)

CDC - National Center for Infectious Diseases

John W. Ward, M.D., Editor
Epidemiology Program Office MS C-08
Centers for Disease Control and Prevention
1600 Clifton Rd.
Atlanta, GA 30333
Fax:(404)639-4198
E-mail: mmwrq@cdc.gov

Waterborne-disease outbreaks associated with drinking water, Waterborne-disease outbreaks
associated with drinking water, by etiologic agent and type of water system, Waterborne-
disease outbreaks associated with drinking water, by type of deficiency and type of water
system, Waterborne-disease outbreaks of gastroenteritis associated  with recreational water,
State,  Month, Etiologic agent, Illness, Number of Cases, Source, Setting

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is redundant with FoodNet (source 74).

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.
                                                         A4-84

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EPA-OGWDW
        Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Source URL
http://www.cdc.gov/mmwr/
Data Source Name

Identification Number

Data Source Description
Proprietor
Multicase

239

See CASE/MCase/MC4PC

Multicase
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
See CASE/MCase/MC4PC

See CASE/MCase/MC4PC

This source is considered relevant for the CCL Universe because it could be a source of
information on potential health effects.

It does not meet considerations because there was no documentation on how the data were

This source is redundant, as it is the same as the Case model (source 238).

This source does not meet retrievability criteria. The source does not contain data; it is a
model that might be used to generate estimates. The source is only available through a

http://www.multicase.com/products/prod01.htm
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Municipal Water Use Database - Environment Canada

125

The MUD database is designed to provide easy access to basic data on municipal water and
wastewater. The 1999 database (spreadsheet) currently contains water and sewage systems
information from Canadian municipalities with populations over 1000. The total population of
these municipalities is 25 million out of a total 1999 Statistics Canada Census population of
30 million. The database is now "Up N Running", debugging and other tests have been
completed. The data are usually released as an Excel95 spreadsheet format, and can be
sorted into a variety of aggregations, including; Provincial, Regional, Hydrologic, population
size groups, and others.

Environment Canada

Mr. David Burke
Policy Analyst
Sustainable Water Use Branch
Environment Canada
Ottawa, Ontario  K1AOH3
Tel.: (819) 934-2486
Fax:(819)994-0237
E-mail: H2O@ec.gc.ca

Bibliographic information, Indexing terms, Abstracts,  Chemical names, and CAS Registry
Numbers

This source does not meet relevance  criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.ec.gc.ca/water/mud/en/index.cfm
                                                       A4-85

-------
EPA-OGWDW
        Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Data Source Name
Identification Number
Data Source Description
National Ambulatory Medical Care Survey (NAMCS)
127
This survey, conducted annually by the CDC since 1989, provides national data on the
utilization and provision of ambulatory care services in hospital emergency and outpatient
departments. The information on pharmaceutical usage may be applicable for estimating
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Retrievability Explanation

Source URL
potential drinking water occurrence of these compounds.
CDC - National Center for Health Statistics
National Center for Health Statistics
3311 Toledo Road
Hyattsville, MD 20782
Phone:(301)458-4000
Patient visit file, Date of visit, Patient's age, Patient's sex, Reason(s) for the visit,
Physician's diagnoses, Medications provided or prescribed, New medication, Additional drug
characteristics, Generic name, Prescription status, Controlled substance status, Composition
status, Drug class, Ingredients, Major reason for the visit, Accidental injury or product-
related illness,  Drug mention file, Medication/drug entry name, Entry status,
Diagnostic/screening services, Counseling/advice, Selected types of therapy, Does patient
This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.
It meets considerations because it is peer reviewed.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www.cdc.aov/nchs/about/maior/ahcd/namcsdes.htm
Data Source Name
Identification Number
Data Source Description

Proprietor

Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
National Animal Health Reporting System (NAHRS)
126
This database, currently in development, is slated to record incidence of certain infectious
diseases among commercial livestock in all 50 states.  Participation of state animal health
officials is voluntary, and no report has been published to date.
U.S. Animal Health Association (USAHA), the American Association of Veterinary Laboratory
 Diagnosticians (AAVLD), and the U.S. Department of Agriculture's Animal and Plant Health
aphis.webmaster@aphis.usda.gov
Microbial outbreak-related data elements for microbial contaminants
This source does not meet relevance criteria because it contains only information on
microbial contaminants.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated  retrieval.
http://www.aphis.usda.gov/vs/ceah/
Data Source Name

Identification Number
Data Source Description
National Cancer Institute Database of 3 Dimensional Chemical
Structures (NCI-3D)
135
Provides substructure searches on 126,554 compounds and SMILES notation (used for
Quantitative Structure Activity Relationships) for 237,771 compounds.  Subsets of this
database have been screened for anti-tumor and anti-Human Immunodeficiency Virus (HIV)
properties with the Developmental Therapeutics Program (DTP) in vitro cell line, representing
                                                       A4-86

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EPA-OGWDW
        Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Proprietor
Contact Information


Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation
Source URL
60 human tumor cell lines.

National Library of Medicine - DSIS; Division of Specialized Information Services

U.S. National Library of Medicine
8600 Rockville Pike, Bethesda, MD 20894
tehip@teh.nlm.nih.gov

CASRN, molecular formula, structure, SMILES

This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://chem.sis.nlm.nih.gov/nci3d/
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information


Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation
Source URL
National Drinking Water Contaminant Occurrence Database (NCOD)
- 6-Year Data

136

The NCOD contains data from both Public Water Systems (PWSs) and the U.S. Geological
Survey National Water Information System (NWIS) regarding contaminants on the current
CCL, for both detections and non-detects. NCOD is a query tool for the underlying
databases and provides summary statistics of national occurrence of regulated and
unregulated contaminants.  The Six Year data set contains detects and concentration
statistics, as well as method reporting limit information, for the 61 chemicals on the Six Year
 Review analysis for ground and surface water.

EPA Office of Ground Water and Drinking Water

Safe Drinking Water Hotline
Phone: 1-800-426-4791
Email: hotline-sdwa@epa.gov

Drinking Water Occurrence Concentrations

This source does not meet relevance criteria because it contains only information for
regulated contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.epa.gov/safewater/data/ncod.html
Data Source Name


Identification Number
Data Source Description
National Drinking Water Contaminant Occurrence Database (NCOD)
- Round 1&2

137

The NCOD contains data from both Public Water Systems (PWSs) and the U.S. Geological
Survey National Water Information System (NWIS) regarding contaminants on the current
CCL, for both detections and non-detects. NCOD is a query tool for the underlying
                                  databases and provides summary statistics of national occurrence of regulated and
                                  unregulated contaminants. This source contains detects and concentration statistics for the
                                  76 chemicals on the Round 1 and 2 analysis for surface and ground water.

                                  "The Round 1  dataset contains public water system monitoring sample results for 62 (then)
                                  unregulated contaminants, generally collected between 1988 and 1992, from 40 states and
                                  primacy entities. These data are from the first round of required monitoring of unregulated
                                  contaminants. Round 1 data were stored in a database called the Unregulated Contaminant
                                  Monitoring Information System (URCIS). The Round 2 dataset (the second round of

                                                       A4-87

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EPA-OGWDW
         Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Proprietor

Contact Information


Type of Data Elements
Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation
Source URL
unregulated contaminant monitoring) contains public water system monitoring sample data
for 48 (then) unregulated contaminants, generally collected between 1993 and 1997, from 35
states and primacy entities. Round 2 data were obtained from the EPA Safe Drinking Water
Information System (SDWIS/FED)."
(description from website)

EPA Office of Ground Water and Drinking Water

Safe Drinking Water Hotline
Phone:  1-800-426-4791
Email: hotline-sdwa@epa.gov

Drinking water occurrence concentrations

This source is considered relevant for the CCL Universe because it contains measurements
of unregulated contaminants in drinking water, demonstrating occurrence.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.epa.qov/safewater/data/ncod.html
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
National Drinking Water Contaminant Occurrence Database (NCOD)
- Unregulated Contaminant Monitoring Rule (UCMR)

233

The NCOD contains data from both Public Water Systems (PWSs) and the U.S. Geological
Survey National Water Information System (NWIS) regarding contaminants on the current
CCL, for both detections and non-detects. NCOD is a query tool for the underlying
databases and provides summary statistics of national occurrence of regulated and
unregulated contaminants.

EPA uses data generated by the UCMR (1999) to evaluate and prioritize contaminants on the
 EPA Contaminant Candidate List (CCL). The CCL is a list of contaminants EPA is
considering for possible new drinking water standards. Additional information on the rule is
available on the UCMR main page.

The occurrence data associated with the revised UCMR (1999) is meant to assist the
Agency in determining whether or not to regulate a certain contaminant. The UCMR (1999)
was designed to assess contaminant occurrence nationally. Therefore, extreme caution
should be used in any interpretation of data, which reflects only a subset of the entire
database. The monitoring is scheduled during the period from 2001 until  2003. So, any
interpretation of data before all the data are collected (probably mid-2004) may lead to false
conclusions.

EPA Office of Ground Water and Drinking Water

Safe Drinking Water Hotline
Phone: 1-800-426-4791
Email: hotline-sdwa@epa.gov
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation
Source URL
(description from website)   Drinking Water Occurrence Concentrations

This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in drinking water, demonstrating occurrence.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.epa.qov/safewater/data/ncod.html
                                                        A4-88

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Data Source Name

Identification Number
Data Source Description
Proprietor

Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
National Environmental Data Index (NEDI)

129

The National Environmental Data Index (NEDI) provides direct access to environmental data
and information descriptions, and thereby, improves awareness of and facilitates access to
data and information holdings. The overall goal of the NEDI is to facilitate the use of the
widest possible range of environmental data and information to support our ability to protect
human health, safety, and welfare; to maintain and restore ecological integrity; and to
sustain economic stability and growth. The NEDI will be a focus for identifying
environmental data and information holdings within the United States and ultimately,
internationally,  (description from website)

National Oceanic and Atmospheric Administration

NOAA Environmental Information Services E/EIS
1335 East West Highway
Room 7226
Silver Spring MD 20910
Phone: 301-713-0816
Fax:301-713-0819

Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data  requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

www.nedi.gov
Data Source Name

Identification Number

Data Source Description
National Health and Nutrition Examination Survey (NHANES)

139

The most relevant portion of NHANES for screening potential drinking water contaminants is
the National Report on Human Exposure to Environmental Chemicals (NRHEEC).
Biomonitoring data include measurements of 27 chemicals, including pesticides (e.g.,
phthalates and organophosphates) and other prevalent chemicals (such as lead and
beryllium) in either the blood or urine of a small but national sample of the U.S. population.
Several databases and journal articles describing other studies (e.g., high blood pressure,
immunization status, and nutritional blood measures) conducted under NHANES III are
available. The NHANES VOC database contains relevant data for over 40 chemicals. Also
useful for occurrence and health effects for contaminant screening may be the General
Mortality tables. These tables include the causes of death for all age groups in the United
States and  include waterborne disease outbreaks.
Proprietor
Contact Information


Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
CDC National Center for Health Statistics

National Center for Health Statistics
Hyattsville, MD 20782
Phone:(301)458-4000

CAS RN, Parameter, Detection limit, Number of samples, Mean, Median, 5th percentile,

This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in either the blood or urine, providing an indicator of occurrence.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.cdc.gov/nchs/nhanes.htm
                                                        A4-89

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Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
National Hospital Discharge Survey (NHDS)

141

NHDS has been conducted annually by CDC since 1965 and provides general summary
statistics of trends in hospital care, such as average age of patients, frequently prescribed
medications, and nature of illness, from patients who have stayed at the hospital for fewer
than 30 days. The data comprise a sample of the 270,000 available inpatient records from
about 500 hospitals nationwide. Information on prescribed medications may be of interest
from this survey,  (description from website)

CDC - National Center for Health Statistics

National Center for Health Statistics
Hospital Care Statistics Branch
Hyattsville, MD 20782
Phone:(301)458-4321

Age, Sex, Race, Ethnicity, Marital Status, Admission and Discharge Dates, Discharge
status, Diagnoses, Procedures

This source is considered relevant for the CCL Universe because it contains information on
prescribed medications. These data might be used as a source of information on potential
occurrence of Pharmaceuticals.

It meets considerations because it is peer reviewed.

This source is redundant, as it is wholly available as part of IPD (source  101).

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.cdc.aov/nchs/about/maior/hdasd/nhds.htm
Data Source Name

Identification Number
National Human Adipose Tissue Survey (NHATS)
140
Data Source Description
Proprietor
Contact Information

Type of Data Elements
Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
NHATS analyzed human adipose tissue specimens to monitor human exposure to potentially
toxic chemicals. A nationwide network of pathologists and medical examiners from 47
metropolitan statistical areas collected tissue specimens from cadavers and surgical patients
that were analyzed for organochlorine pesticides, PCBs, and volatile and semivolatile
organic compounds. NHATS contains biomonitoring data for over 150 chemicals, and
analyses for a variety of toxic compounds, using standardized protocols on composite
categorizations that represent nine regions and three age groups. More detailed information
is available in "Broad scan analysis of the FY82 National Human Adipose Tissue Survey
specimens" Volume 1-Executive Summary, EPA Document No. EPA-560/5-86-035,
Washington D.C., Phillips and Birchard, Arch. Environ. Contam. Toxicol., 21, 1991, pp. 159-
168. (description from website)

Also see: http://books.nap.edu/books/0309044375/html/index.html
This book provides a fairly comprehensive description of the process used for this survey.

EPA Office of Toxic Substances

OSCPweb@epa.gov

Chemical name, CAS RN, Year, Number of Analyses, Arithmetic/Geometric Mean, Lowest
Arithmetic/Geometric Mean, Number of Analyses with Lowest Arithmetic/Geometric Mean,
Highest Arithmetic/Geometric Mean, Number of Analyses with Highest Arithmetic/Geometric
Mean

This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in human adipose tissue, providing an indicator of occurrence.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://cfpub.epa. aov/ncea/cfm/recordisplav.cfm?deid=55204
                                                        A4-90

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Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
National Human Exposure Assessment Survey (NHEXAS)

249

The National Human Exposure Assessment Survey program is designed to evaluate
comprehensive human exposure to multiple chemicals on a community and regional scale.
The focus of NHEXAS is on the exposure of people to environmental pollutants in their daily
lives. Samples were collected of the air that people breathe, the food that they eat, the
water and beverages that they drink, of the soil and dust around their homes, and of their
blood and urine. Preliminary results of Phase I of NHEXAS are reported  in 15 journal articles
 published in the September-October 1999 issue of the Journal of Exposure Analysis and
Environmental Epidemiology.  The journal articles are summarized in Table 1. Seven of the
15 journal articles provide information that is applicable for inclusion in the Endocrine
Disrupter Priority-Setting Database. Altogether the seven journal articles provide data on 25
compounds and approximately 20 media. Table 2 lists the compounds and provides
information on the media for which data is reported for them, (from ERG data source memo)

Center for Disease Control, Environmental  Health Laboratory

Edo Pellizzari
edp@rti.org
Tel: 919.541.6579
Fax: 919.541.6161
3040 Cornwallis Road
Post Office Box 12194
Research Triangle Park, NC 27709-219
http://www.rti. org/page.cfm?objectid=A892862B-ODBO-4405-BB30056DB2611983

Name, CAS RN, Central tendency, Units, Method of Measurement, Number of samples,
Percent of the samples that were measurable, Population, Water Type, Location, Season
Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation
Source URL
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.

It meets considerations because it is peer reviewed.

This source is redundant, as it is wholly available as part of HEDS (source 92).

This source meets retrievability criteria because  it is in tabular format.

http://www.epa.gov/heasd/edrb/nhexas.htm
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
National Inorganics and Radionuclides Survey (NIRS)

144

NIRS was designed and conducted by EPA specifically to provide data on the occurrence in
ground water of a set of 42 radionuclides and inorganic chemicals (lOCs) being considered
for National Primary Drinking Water Regulations (NPDWRs). NIRS provides contaminant
occurrence data from a statistical sample comprised of 989 nationally representative
community public water systems served by ground water, in 49 states and Puerto Rico that
treat ground water for distribution. Samples were collected from the distribution system
subsequent to treatment.  Each of these randomly selected public water systems was
sampled a single time between 1984 and 1986.

EPA OGWDW; The Cadmus Group, Inc.

Tom Carpenter
U.S. EPA
Office of Ground Water and Drinking Water
1200 Pennsylvania Ave NW
Washington, DC 20460
T: 800-426-4791

Drinking Water Occurrence Concentrations

This source is considered relevant for the CCL Universe because it contains measurements

                      A4-91

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EPA815-R-09-006
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Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
         of contaminants in water, demonstrating occurrence.

         It meets considerations because it is peer reviewed.

         This source is not redundant.

         Data are retrievable by EPA.  They may require special processing for analysis for CCL use.

         Error! Hyperlink reference not valid, source not available.  Summary of data provided in tabular
        form  in docket; www.reaulations.gov Docket ID EPA-HQ-OW-2007-1189
Data Source Name
National Institute for Occupational Safety and Health (NIOSH) - Index
         of Occupational Health Guidelines for Chemical Hazards
Identification Number
Data Source Description
Proprietor
Contact Information
         143

         Occupational Health Guidelines for Chemical Hazards summarize information for over 675
         substances on names and synonyms: Permissible Exposure Limits in air, chemical, and
         physical properties; and health hazards.  In addition, these guidelines are revised when new
         information is made available, or when deemed necessary, and the revised documents are
         also available at the same web site. These guidelines may be of use when evaluating the
         health effects of certain drinking water contaminants where inhalation exposure may be
         relevant (as most workplace exposures are from inhalation during production of the
         contaminant).

         CDC National Institute for Occupational Safety and Health (NIOSH)

         Centers for Disease Control and Prevention
         1600 Clifton Rd
Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retriev ability Explanation

Source URL
         Atlanta, GA 30333, USA
         Tel (404) 639-3311
         Public Inquiries (404) 639-3534 / (800) 311 - 3435

         Formula, Structure, Appearance and odor,
         Physical Data, Reactivity, Flammability, OSHA PEL, NIOSH REL, ACGIH TLV, Rationale


         This source is considered relevant for the CCL Universe because it contains data elements
         from toxicological studies.

         It meets considerations because it is peer reviewed.

         This source is not redundant.

         This source does not meet retrievability criteria because the data are not formatted for
         automated retrieval.

         http://www.cdc.gov/niosh/docs/81 -1237
Data Source Name


Identification Number
Data Source Description
Proprietor

Contact Information
         National Institute of Enviornmental Health Sciences (NIEHS)
         Reproductive Toxicology Group

         142

         The Reproductive Toxicology Group researches the adverse health effects of chemicals and
         other environmental agents on fecundity, germ cell genetics, and development. The group
         generates toxicity data through in-house research, and provides this data to regulatory
         agencies and public health groups. The website provides an index of which environmental
         agents have been researched, and in what capacity, (description from website)

         NIEHS - Reproductive Toxicology Group; National Institute of Environmental Health and
         Safety (NIEHS)

         Robert E. Chapin, PhD
         NIEHS
         PO Box 12233
         MD B3-05 Research Triangle Park, NC 27709
         Phone 919/541-3474
         Fax 919/541-4634
         Email Chapin@niehs.nih.gov
                              A4-92

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Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Chemical Name, CAS number, Test
This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://dir.niehs.nih.aov/dirtb/dirrta/chemicalsstudiedindex2.htm
Data Source Name
Identification Number
National Nosocomial Infections Surveillance System (NNIS)
145
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
This database is a national cooperative effort between the CDC and participating hospitals to
 create a nosocomial (hospital-related) infections database. The database describes the
epidemiology of nosocomial infections, describes the antimicrobial resistance trends, and
can be used to produce infection rates. The program began in 1970, with approximately 315
hospitals participating and voluntarily surveying and reporting results to CDC at the
beginning of 2000. (description from website)
CDC, Division of Healthcare Quality Promotion
Centers for Disease Control and Prevention
1600 Clifton Rd
Atlanta, GA 30333, U.S.A
Tel: (404) 639-3311
Public Inquiries: (404) 639-3534 / (800) 311-3435
Antimocrobial-resistant pathogen, No. units, No. tested, Pooled mean, Percentile
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated  retrieval.
http://www.cdc.aov/ncidod/hip/SURVEILL/NNIS.HTM
Data Source Name
Identification Number
Data Source Description

Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
National Notifiable Diseases Surveillance System
130
The CDC have designated 60 infectious diseases as "national notifiable diseases." State
and local authorities report incidences of these diseases to CDC, which compiles
surveillance data in its MMWR. Data from 1996 to the present.
CDC
John W. Ward, M.D., Editor
Epidemiology Program Office MS C-08
Centers for Disease Control and Prevention
1600 Clifton Rd.
Atlanta, GA 30333
Fax:(404)639-4198
E-mail:  mmwrq@cdc.gov
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
Completeness Explanation      It meets considerations because it is peer reviewed.
                                                       A4-93

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        Final CCL 3 Chemicals:
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Redundancy Explanation
Retrievability Explanation

Source URL
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www.cdc.aov/mmwr/distrnds.html
Data Source Name
National Notifiable Diseases Surveillance System (Australia)
Identification Number
Data Source Description
Proprietor
Contact Information

Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
131
The Communicable Diseases Network Australia collects data from departmental health
authorities on the occurrence of 61 infectious diseases.  Annual, monthly, and outbreak data
are reported. Several diseases listed in this system may be transmitted via water, including:
Cryptosporidiosis, Hepatitis A and E, Legionellosis, Salmonellosis, and Shigellosis.
Australian Department of Health and Aging; The Communicable Diseases Network Australia
GPO Box 9848
Canberra ACT 2601, Australia
cdi.editor@health.gov.au
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.cda.gov.au/surveil/
Data Source Name
Identification Number
Data Source Description

Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
National Occupational Exposure Survey (NOES)
146
NOES was a nationwide observational survey conducted between 1981 and 1983 on a
sample of nearly 5,000 establishments, a selection designed to represent those segments of
American industry covered under the Occupational Safety and Health Act of 1970.
CDC National Institute for Occupational Safety and Health (NIOSH)
Centers for Disease Control and Prevention
1600 Clifton Rd
Atlanta, GA 30333, USA
Phone: 1-800-35-NIOSH  (1-800-356-4674)
Fax: 1-513-533-8573
CAS RN, Name, Standard industrial classification (SIC) code, Number of workers exposed
to the substance, Number of facilities handling the material
This source is considered relevant for the CCL Universe because it contains information that
is related to potential exposure.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, however some tabular data have been obtained from ERG.
http://www.cdc.gov/niosh/pdfs/89-103-b.pdf
                                                       A4-94

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Data Source Name
Identification Number
National Pesticide Information Retrieval System
261
Data Source Description
The National Pesticide Information Retrieval System (NPIRS®) is a collection of pesticide-
related databases available by subscription. NPIRS® is under the administration of the
Center for Environmental and Regulatory Information Systems, CERIS, at Purdue
University in West Lafayette, Indiana.

There are five (5) databases and three (3) dictionaries (vocabularies) available for searching.
                                    Databases:
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
Federal and State Pesticide Product
Pesticide Document Management System (PDMS)
Data Submitters List
Tolerance Index
Federal Register Archive
Dictionaries:

Chemical       - active ingredient accepted label names, chemical synonyms, CAS
                 Registry Numbers, EPA chemical codes, brand and trade names
Site            - site names, methods and times of application, site codes
Pest           - common pest names, life cycles, pest codes
Over 400 individuals access NPIRS® for information pertaining to product registration.
Many individuals use NPIRS® to assist in registering pesticides and developing market
strategies based on currently registered products or pending registrations,  (description from
website)

CERIS, Purdue University

CERIS/NPIRS®
1231 Cumberland Avenue, Suite A
West Lafayette IN 47906-1317 Office:  765-494-6616
FAX:   765-494-9727
WEB Info Site:  http://ceris.purdue.edu/npirs

Chemical, Site, Pest, Federal  brand names, EPA registration number, Product status,
Registrant name and address, Product formulation, Federal restricted use status, Use type
classifications, Active ingredients, Registration action dates, Sites on which to use product,
Pests controlled, Site/pest combinations, Special Local Need registrations (SLNs), State
brand names, State registration numbers, Year of last registration, Document title and
author, Submitters (first/all), Research subjects, CFR part and paragraph, Parts per million
levels, FR dates, Full text of articles, Article dates, Citations, Departments/agencies, CFR

This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.

It meets  considerations because it meets all NDWAC minimum data requirements.

This source is redundant with  the Pesticide Data Submitters' List, the Pesticide Product
Information Database,  and the Pesticide Tolerance Index.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://ceris.purdue.edu/npirs/index.html
Data Source Name
Identification Number
Data Source Description
National Pesticide Use Database

128

The National Pesticide Use Database was created by the National Center for Food and
Agricultural Policy (NCFAP) in conjunction with the United States Department of Agriculture.
The National Pesticide Use Database compiles state and crop pesticide use data from
publicly available reports and from surveys conducted by the National Agricultural Statistics
Service. First-issued in 1995, the NCFAP pesticide use database is widely used by
governmental agencies, environmental groups and private industry. In  November 2000,
NCFAP released an updated version of the national database which delineates the use of
220 active ingredients on 87 crops in the 48 contiguous states in  1997.

                      A4-95

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                                  Note: Although 1992 and 1997 are benchmark years for the database, the data for these
                                  years are derived from use estimates made between 1990 to 1993 and 1994 to 1998,
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
respectively. The NCFAP databases are more accurately described as circa 1992 and circa
1997.

Users are advised to read the report Pesticide Use in U.S. Crop Production: 1997, that
describes how the database was compiled and identifies the references that were used as
the source for each record in the database. A detailed description of the internet files is also
included in this report, (description from website)

National Center for Food and Agricultural Policy (NCFAP)

National Center for Food and Agricultural Policy
1616 P Street NW, First Floor
Washington, DC 20036
Phone: 202-328-5048
ncfap@ncfap.org
Nathan Reigner
Phone: (202) 328-5005
Email: reigner@ncfap.org

Name, Ibs Al applied, # States applied

This source is considered relevant for the CCL Universe because it contains information on
pesticide use, an indicator of potential occurrence.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.ncfap.org/pesticideuse.html
Data Source Name


Identification Number

Data Source Description
Proprietor

Contact Information


Type of Data Elements
Relevance Explanation

Completeness Explanation

Redundancy Explanation
National Reconnaissance of Emerging Contaminants (NREC) -
USGS Toxic Substances  Hydrology Program

132

This database is currently in compilation and will include occurrence data collected by the
USGS Toxic Substances Hydrology Program from 1999 to 2001 in samples from 142
streams, 55 wells, and seven effluent samples from 36 states.  The majority of the sites
sampled were expected to be susceptible to emerging contaminants through the pathway of
either animal or human wastewater.  A smaller subset of the sites were located in settings
where occurrence of emerging  contaminants was predicted to be unlikely.  A total of 94
target chemicals were measured, including 22 human and veterinary antibiotics, 13
prescription drugs, five nonprescription drugs, 39 industrial and household wastewater
products (e.g., caffeine and personal care products), and 15 reproductive and steroidal
hormones. This review refers to the USGS Open File Report (02-94) available on the USGS
website. This online report includes all the raw data from the stream sampling portion of the
study.

USGS

District Chief  U.S. Geological Survey
P.O.  Box 1230
Iowa City, Iowa 52244

Ambient Water Occurrence Concentrations, Min,  Max Value

This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.

It meets considerations because it is peer reviewed.

This source is not redundant.
Retrievability Explanation

Source URL
This source meets retrievability criteria because USGS provided the data directly to EPA in a
 useable format.

http://toxics.usgs.gov/regional/emc.html
                      A4-96

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Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
National Research Council (NRC) Publications

147

The National Research Council is part of the National Academies, which also comprise the
National Academy of Sciences, National Academy of Engineering and Institute of Medicine.
They are private, nonprofit institutions that provide science, technology and health policy
advice under a congressional charter. The Research Council was organized by the National
Academy of Sciences in 1916 to associate the broad community of science and technology
with the Academy's purposes of further knowledge and advising the federal government.

Functioning in accordance with general policies determined by the Academy, the National
Research Council has become the principal operating agency of both the National Academy
of Sciences and the National Academy of Engineering in providing services to the
government, the public and the scientific and engineering communities. The Research
Council is administered jointly by both Academies and the Institute of Medicine through the
National Research Council Governing Board. The chairman of the National Research Council
 is Bruce Alberts, (description from website)

National Research Council, National Academies Press

National Academies Press
500 Fifth Street, NW
Lockbox 285
Washington, DC 20055
Phone: 888-624-8373 or 202-334-3313
email: zjones@nas.edu
Fax: Customer Service/General (202) 334-2451

Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated  retrieval.

http://www.nap.edu/
Data Source Name

Identification Number

Data Source Description
Proprietor
National Sanitary Foundation (NSF) - Additives Standards 60 and 61

148

NSF 60, Drinking Water Treatment Chemicals - Health Effects is the nationally recognized
health effects standard for chemicals which are used to treat drinking water. NSF 61,
Drinking Water System Components - Health Effects is the nationally recognized health
effects standard for all devices, components and materials which contact drinking water.
(description from website)

National Sanitary Foundation
Contact Information
Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation
777 East Eisenhower Parkway
Ann Arbor, Ml 48108
Email: service@techstreet.com
Phone: (800) 699-9277
Fax:(734)913-3946

This source is considered relevant for the CCL Universe because it contains information on
health effects standards for drinking water.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
                                                        A4-97

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Source URL
http://www.techstreet.com/cgi-bin/detail7product  id=1155045
Data Source Name

Identification Number

Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
National Sediment Inventory (NSI)

149

The NSI is a database that documents the composition of sediment in rivers, lakes, oceans,
and estuaries.  It also incorporates an assessment of potential human and environmental
health effects of the contaminants in the sediment. Data sources for the study included
sediment chemistry data, chemical residue level data in edible tissue of aquatic organisms,
and sediment toxicity studies, which were collectively assembled from more than 21,000
sampling stations nationwide. This database is of potential interest because sediments can
contribute contaminants to drinking water, (description from website)

EPA Office of Water, OST

U.S. Environmental Protection Agency
Office of Water
Office of Science and Technology (4301T)
1200 Pennsylvania Avenue,  N.W.
Washington, D.C. 20460

Analyte sampled, Mean, Max, Median, Min, Measured/estimated value, Fraction organic
carbon, Nondetect flag, Number of samples, Units

This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in sediments (which can contribute contaminants to drinking water), and can
indicate potential occurrence.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.


http://vosemite.epa.aov/water/owrccataloa.nsf/065ca07e299b464685256ce50075c11a/d6f0480aOeb
387fd85256d83004fd809!OpenDocument
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
National Stream Quality Accounting Network (NASQAN)

133

According to the web site, the primary goals of the NASQAN are to "characterize large sub-
basins of rivers, to determine regional source areas for chemical contaminants, and to
assess the effects of human influences on observed concentrations and amounts of the
chemicals." Since 1995, NASQAN has focused on monitoring the concentration of a broad


range of chemicals including pesticides, major ions, and trace elements in four of the
nation's largest river systems: the Mississippi, the Columbia, the Colorado, and the  Rio
Grande.  NASQAN contains data relevant to contaminant screening, such as occurrence of
major ions, trace elements, and dissolved pesticides. Most of the data are easily exportable
 in tabular form.

USGS

Office of Water Quality
U.S. Geological Survey
412 National Center
Reston, Virginia 20192
Internet: http://water.usgs.gov/nasqan

Occurrence concentrations

This source is considered relevant for the CCL Universe  because it contains measurements
of contaminants in water, demonstrating occurrence.

It meets considerations because it is peer reviewed.
                      A4-98

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         Final CCL 3 Chemicals:
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Redundancy Explanation
Retrievability Explanation

Source URL
This source is redundant with NAWQA.

This source meets retrievability criteria because the relevant data can be extracted in tabular
format.

http://water.usas.aov/nasaan/progdocs/wri014255/index.htm
Data Source Name

Identification Number
Data Source Description
National Toxicology Program (NTP) Health and Safety Profiles

150

The NTP has developed around 500 "Toxicity and Carcinogenicity" reports and 66 "Toxicity"
reports for organic and inorganic chemicals. These reports summarize toxicological data and
includes some carcinogenicity and toxicity endpoints and categorizations.  Another important
feature of the "Toxicity and Carcinogenicity" reports is a strength of evidence categorization
for the conclusions drawn in the studies.
                                   Agents may be nominated to the NTP for study by any person or group regardless of
                                   affiliation. The nominations go through a rigorous internal and external scientific review to
                                   determine the need for testing and a check with Government Agencies to see if the use of
                                   an agent falls under any Federal Regulations. Once an agent has been selected by the NTP
                                   Executive Committee for study, a staff scientist is assigned to develop appropriate study
                                   protocols to obtain the needed toxicity data. Using these protocols, the toxicity studies are
                                   conducted at contract laboratories under a standard set of operational guidelines. Each
                                   laboratory is required to have a health and safety plan in place for each chemical to protect
                                   their workers.
Proprietor
Contact Information
Type of Data Elements
Between 1978 and 1991 a contractor assembled health and safety background information
for chemicals selected for study by the Program. These documents were provided to the
laboratories at the time they conducted the agent studies to help them develop the individual
 health and safety plans. It is this set of files that we have on our web site. Currently, the
responsibility for assembling this health and safety information is that of the testing
laboratory, (description from website)

National Toxicology Program; NIH

NTP Liaison and Scientific Review Office
P.O. Box 12233, MDA3-01
Research Triangle Park, NC 27709
Telephone:  (919) 541-0530
E-mail: liaison@starbase.niehs.nih.gov
ntpwm@niehs.nih.gov

BP, Carcinogenicity, Critical effects, Dose, Duration, GenTox, GMM Abstract, GMM Care,
GMM GenTox, GMM Neo, GMM Nonneo, Hazard class, MP, Mutation Data, Other toxicity
data, Path, RACE Abstract, Rationale for testing, RDGT Abstract, Reactivity, Route, SAX
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
toxicity evaluation, Species, Stability, Statistical analysis, Strain and Species, Study Result,
 Study Type, Subsidiary Risk, Survival, Growth weights and Gross observations,
Teratogenicity, Tissue, Tox Abstracts, TOX Growth Surv, Toxicity, Toxicokinetic, TR Care
act, TR Gen Tox, TR Neo, TR Nonneo, TR Path Surv Growth, TR Target Org, Use, Vapor
Density, Vapor Pressure, Water Solubility

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://ntp-server.NIEHS.nih.gov/
Data Source Name

Identification Number
Data Source Description
National Toxicology Program (NTP) Studies

248

The NTP has developed around 500 "Toxicity and Carcinogenicity" reports and 66 "Toxicity"
                      A4-99

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EPA815-R-09-006
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Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
reports for organic and inorganic chemicals. These reports summarize toxicological data and
includes some carcinogenicity and toxicity endpoints and categorizations. Another important
feature of the "Toxicity and Carcinogenicity" reports is a strength of evidence categorization
for the conclusions drawn in the studies.

Agents may be nominated to the NTP for study by any person or group regardless of
affiliation. The nominations go through a rigorous internal and external scientific review to
determine the need for testing and a check with Government Agencies to see if the use of
an agent falls under any Federal Regulations. Once an agent has been selected by the NTP
Executive Committee for study,  a staff scientist is assigned to develop appropriate study
protocols to obtain the needed toxicity data. Using these protocols, the toxicity studies are
conducted at contract laboratories under a standard set of operational guidelines. Each
laboratory is required to have a  health and safety plan in place for each chemical to protect
their workers.

Between 1978 and 1991  a contractor  assembled health and safety background information
for chemicals selected for study by the Program. These documents were provided to the
laboratories at the time they conducted the agent studies to help them develop  the individual
 health and safety plans.  It is this set of files that we have on our web site. Currently, the
responsibility for assembling this health and safety information is that of the testing
laboratory, (description from website)

National Toxicology Program; NIH

NTP Liaison and Scientific Review Office
P.O. Box 12233, MDA3-01
Research Triangle Park,  NC 27709
Telephone: (919)  541-0530
E-mail: liaison@starbase.niehs.nih.gov
ntpwm@niehs.nih.gov

Name,  Synonyms, CASRN, Formula,  Structure, Categories of evidence of carcinogenic
activity, Statistical results

This source is considered relevant for the CCL  Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does  not meet retrievability criteria  because the data are not formatted for
automated retrieval. NTP studies provide unique and exceptional data and are included to
supplement the CCL Universe.
Source URL
http://ntp-server.NIEHS.nih.gov/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
National Water Information System (NWIS Web)

151

As part of its program of disseminating water data to the public, the USGS maintains a
distributed network of computers and file-servers for the storage and retrieval of water data
collected through its activities at approximately 1.5 million sites around the country. This
system is called the National Water Information System (NWIS). Many types of data are
stored in this NWIS network, including: site information, time-series (flow, stage,
precipitation, chemical), peak flow, ground water, and water quality.  NWIS data comes from
all 50 states, selected territories, and border stations, from 1896 to the present, (description
from website)

USGS

Questions about data h2oteam@usgs.gov

Occurrence Concentrations

This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.

It meets considerations because it is peer reviewed.

This source is redundant with NAWQA.
                                                         A4-100

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Retrievability Explanation
Source URL
This source meets retrievability criteria because it is in tabular format.

http://waterdata.usas.gov/nwis
Data Source Name

Identification Number
Data Source Description
Proprietor

Contact Information
National Water Quality Assessment (NAWQA)

134

The NAWQA database, maintained by USGS, describes the status and trends in the quality
of the nation's groundwater and surface water resources.

The U.S. Geological Survey (USGS) began its NAWQA (National Water Quality Assessment)
 program in 1991, systematically collecting chemical, biological, and physical water quality
data from 42 study units (basins) across the nation. The data warehouse currently contains
and links the following data up through 9/30/2002:
Chemical concentrations in water, bed sediment, and aquatic organism tissues for about 609
chemical constituents
Site, basin, well and network characteristics with many descriptive variables
Daily stream flow information for fixed sampling sites
Ground water levels for sampled wells
6,400 surface water sites and 7,000 wells
44,000 nutrient samples and 26,000 pesticide samples as well  as 8,000 VOC samples
2,650 samples of bed sediment and aquatic organism tissues

This database may be useful for examining nationally representative pesticide and VOC
occurrence in ambient water and drinking water sources; however, the composition and
presentation of the data vary widely from region to region. NAWQA provides high-quality,
nationally representative data reviewed by the National Academy of Sciences (NAS).
(description from website)

USGS

NAWQA Headquarters
Phone: 1-703-648-5716
E-mail: nawqa_whq@usgs.gov
Maintainer: James Ulrich
Type of Data Elements
Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
E-mail: julrich@usgs.gov

Occurrence Concentrations

This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because USGS provided the data directly to EPA in a
 useable format.

http://water.usgs.gov/nawga/
Data Source Name

Identification Number
Data Source Description
NIOSHTIC

279

NIOSHTIC®  is a bibliographic database of literature in the field of occupational safety and
health. About 160 core, English language technical journals provide approximately 35 percent
of the additions to NIOSHTIC® annually. Over 4,000 other sources of technical articles and
reports.
Because NIOSH examines all aspects of adverse effects experienced by workers, much of
the information contained in NIOSHTIC® has been selected from sources that do not have a
primary occupational safety and health  orientation.

The CIS subset of NIOSHTIC® records  are required to provide a CAS Registry Number and
discuss one or more of the following subjects: Hazmat, Biodegradation, Environmental  Fate,
Gastrointestinal Absorption, Toxicity, Carcinogenicity, Turmorigenicity, Mutagenicity,
Teratogenicity, Acid Dissociation, Irritation Data, Occupational Concentrations,
                                                        A4-101

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                                   Bioconcentration Factor, Effluent Concentrations, Photooxidation, Ultraviolet Absorption,
                                   Volatilization, Superfund Sites, or Occupational Safety.
Proprietor
Contact Information
Type of Data Elements
SUBJECT COVERAGE:

behavioral sciences
biochemistry, physiology and metabolism
biological hazards
chemistry
control technology
education and training
epidemiological studies of disease/disorders
 ergonomics
hazardous waste
health physics
occupational medicine
pathology and histology
safety
toxicology
(description from website)

National Information Services Corporation (NISC)

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Bibliographic information, Indexing terms, Abstracts, Chemical names, and CAS Registry
Numbers
Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http://www.nisc.com/cis/details/nioshtic.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Office International des Epizooties (OIE) Handistatus II

155

The current prototype for Handistatus II (i.e Help with World Animal Disease Status - version
 2) is a Web application containing information on animal diseases that have serious
consequences for international trade or public health. This information is regularly updated
based on the emergency, monthly and annual reports sent to the Central Bureau of the
Office International des Epizooties (OIE) by the veterinary administrations of countries and
other official sources.

The annual information on the animal health situation worldwide is almost entirely derived
from the collection and processing of the questionnaires on animal health, common to the
Food and Agriculture Organization of the United Nations (FAO), the World Health
Organization (WHO) and the OIE, which the OIE has distributed to all countries on behalf of
the three organisations since 1996. (description from website)

Office International des Epizooties

Unknown

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains

                      A4-102

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      August 2009
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
only information on microbial contaminants.
It does not meet considerations because no contact information or information on type of
data elements is available.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.oie.int/hs2/report.asp?lang=en
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Office Internationales Epizooties
244
Animal and human health statistics (AWWA)
DIE
Unknown
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It does not meet considerations because no contact information or information on type of
data elements is available.
This source is identical to Office International des Epizooties (OIE) Handistatus II (source
155).
This source meets retrievability criteria because it is in tabular format.
http://www.oie.int/hs2/report.asp?lang=en
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Office of Pollution Prevention and Toxics (OPPT) Chemical Fact
Sheets
156
OPPT Chemical Fact Sheets provide a brief summary of information on selected TRI
chemicals.  Each of the approximately 30 Fact Sheets covers each chemical's identity,
production and use, environmental fate, and health and environmental effects. Each also
includes a list of laws under which the chemical is regulated, phone numbers, and the names
of EPA offices and other agencies one can call or contact for more information.
EPA Office of Pollution Prevention and Toxics
US EPA
Office of Pollution Prevention & Toxics
1200 Pennsylvania Avenue, NW
Mail Code 7401-M
Washington, DC 20460
Phone:(202)564-3810
Email: oppt.homepage@epa.gov
What is the contaminant,  how is it used, and how might I be exposed? What happens to the
contaminant in the environment? How does the contaminant affect human health and the
environment? What EPA program offices regulate the contaminant, and under what laws is it
regulated? What other federal agencies or groups can I contact for information on the
contaminant?
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies and environmental fate data, providing an indicator of potential
It meets considerations because it meets all NDWAC minimum data requirements.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
                                                      A4-103

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Source URL
automated retrieval.

http://www.epa.gov/opptintr/chemfact/
Data Source Name
Identification Number
Data Source Description
Oil and Hazardous Materials/Technical Assistance Data System

287

This database includes 1,402 MSDS-like fact sheets prepared by the US Environmental
Protection Agency in the 1970s and 1980s. Each fact sheet deals with one chemical
substance. The database is no longer updated, and some material in the database has been
rendered incorrect over time by changes in regulatory requirements. However, the database
still contains a wealth of still-useful data and references. Consequently, each record is
presented with a warning about the age of the database and the need to verify critical
information through more current sources. Users can retrieve records by CAS Registry
Number (the preferred method), chemical name, and/or subject terms/phrases.
                                   SUBJECT COVERAGE :

                                   * CAS Registry Numbers * General Toxicology
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
* Chemical Identification * Hazards
* Chemical/Physical Properties * Human Contact and Exposure
* Detection * Reactivity
* Emergency Response  * Plant Toxicology
* Environmental Fate  * Response and Disposal
* Environmental Chemistry * Transportation and Storage
* Fire Protection and Explosion
(description from website)

National Information Services Corporation (NISC)/EPA

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

CAS RN, General Toxicology, Hazards, Chemical/Physical Properties, Human Contact and
Exposure, Detection, Reactivity, Emergency Response, Plant Toxicology, Environmental

This source is considered relevant for the CCL Universe because it contains environmental
fate data, that may be used as an indicator of potential  occurrence.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.nisc.com/cis/details/ohm-tads.htm
Data Source Name
Identification Number
Data Source Description
Oncologic

237

The Cancer Expert System is a personal computer software program developed under a
cooperative agreement between EPA's Office of Pollution Prevention and Toxics (OPPT) and
 LogiChem, Inc. The IBM-compatible DOS (non-Windows) program is registered under the
trademark OncoLogic®. The Cancer Expert System or OncoLogic® can analyze a chemical
structure to determine the likelihood that it may cause cancer. This is done by applying the
rules of structure activity relationship (SAR) analysis and incorporating knowledge of how
chemicals cause cancer in animals and humans.

The Cancer Expert System is comprised of four subsystems that evaluate fibers, metals,
                     A4-104

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Proprietor
Contact Information
polymers, and organic chemicals of diverse chemical structures. The program applies SAR
analysis to predict the potential cancer-causing effects of a chemical. In addition to SAR
analysis, the Cancer Expert System applies the knowledge gained from studies of how
chemicals cause cancer in animals and humans,  (description from website)

Logichem

Logichem,  Inc.
P.O. Box 357
Boyertown, PA 19512
Telephone: 717-420-9417
Telefax: 717-420-9419
E-mail: webinfo@logichem.com
Internet: http://www.logichem.com
Type of Data Elements
Relevance Explanation

Completeness Explanation

Redundancy Explanation

Retrievability Explanation

Source URL
Rating of carcinogenicity potential, Scientific rationale for rating

This source is considered relevant for the CCL Universe because it could be a source of
information on potential health effects.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria. The source does not contain data; it is a
model that might be used to generate estimates. The source is only available through a

http://www.epa.aov/opptintr/cahp/actlocal/can.html
Data Source Name


Identification Number
Data Source Description
Organisation for Economic Co-operation and Development (OECD)
Integrated  HPV Database

152

This database tracks all High Production Volume (HPV) chemicals through the process of
investigation in the OECD Programme on the Investigation of Existing Chemicals). It allows
Member countries and industry to select chemicals for sponsorship and shows the stage of
investigation of any particular chemical at any given time. Finally, once agreed in the
OECD, it shows the results of assessments as well as the actual reports and background
information behind them.
                                   The database contains the list of HPV chemicals together with any annotations on each
                                   chemical provided to the Secretariat by Member countries. Each chemical is identified as to
                                   exactly which stage it is at in the assessment process, and for those chemicals which have
                                   already been selected for sponsoring (i.e. SIDS chemicals), there are links to relevant
                                   documents.

                                   When making the first evaluation of an existing chemical, a minimum set of data is
                                   necessary to determine its potential hazards. To ensure that such data are available, OECD
                                   developed the SIDS (Screening Information Data Set). The SIDS outlines the minimum data
                                   elements essential for determining whether or not a chemical requires further investigation.
                                   When data gaps for a specific chemical are identified, testing is carried out by the chemical
                                   industry.

                                   The database operates at three levels (Secretariat, Member country and general public) with
                                   control of significant data input (such as confirmation of sponsorship) being at the
                                   Secretariat level. Once a chemical has been sponsored  by a Member country, that country
                                   inputs specific information on the investigation of the chemical.

                                   The database has a comprehensive search facility allowing searches to be made in a number
                                    of categories: e.g., chemical name, CAS number, sponsoring country, stage of
                                   investigation. Those chemicals which have not yet been selected for sponsorship can be
                                   readily identified thus facilitating future sponsorship by both Member countries and industry.
                                   Members of the general public have "read only" access to the database and so can follow
                                   the progress of a chemical both through and after its assessment. They can also obtain
                                   completed assessments on individual chemicals once these have been agreed in the OECD.
                                                         A4-105

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Proprietor
Contact Information
Type of Data Elements
Organisation for Economic Co-operation and Development

Mr. Oscar Hernandez
Risk Assessment Division, Office of Prevention, Pesticides & Toxics
US-EPA (7403)
ICC Building, 1200 Pennsylvania Avenue, N.W.
20460 Washington D.C.
United States
Tel: (1-202) 564-0930 Fax: (1-202) 564-7450
E-mail: hernandez.oscar@epa.gov

Name, CASRN, SIDS status
Relevance Explanation
list of HPV
Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
(description from website)    This source is considered relevant for the CCL Universe because it is a

chemicals, which may indicate possible occurrence. It also contains data elements from
toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://cs3-ha.oecd.org/scripts/hpv/
Data Source Name

Identification Number
Data Source Description

Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation
Source URL
OSHA 1988 Permissible Exposure Limits (PELs)

234

Record of OSHA regulatory decisions (AWWA)

NIOSH

Centers for Disease Control and Prevention
1600 Clifton Rd
Atlanta, GA 30333, USA
Phone: 1-800-35-NIOSH (1-800-356-4674)
Fax: 1-513-533-8573

Name, CAS RN, OSHA PEL

This source is considered relevant for the CCL Universe because it contains inhalation
exposure limits, which may provide information on potential health effects.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.osha.gov/SLTC/pel/
Data Source Name


Identification Number
Data Source Description
Palm Top Emergency Action for Chemicals (PEAC-CW System)
Federal Technical Support Working Group

163

The Technical Support Working Group, a Federal Interagency group focusing on developing
new technology for combating Terrorism has sponsored the upgrade of the commercially
available Palmtop Emergency Action for Chemicals (PEAC) system. The PEAC-CW lists
over 10,000 toxic chemicals and includes 6 chemical warfare agents and 73 precursor
chemicals, This capability was designed for use by Federal emergency and law enforcement
officers, and all State and Local Fire, Law Enforcement, HAZMAT, Bomb Squad, and other
emergency/public government services organizations who may be involved with responding
to terrorists, HAZMAT incidents, or other chemical spill emergencies.

The PEAC-CW system contains information from  a number of sources, including NIOSH,
NFPA, AIHA, MSDS, and DOT for over 10,000 chemicals and synonyms searchable by its
                    A4-106

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         Final CCL 3 Chemicals:
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EPA815-R-09-006
      August 2009
                                   chemical name or UN number including:

                                   Proprietary dispersion model that develops site specific Protective Action Distances based
                                   on input for meteorology, surrounding terrain, container size and orientation, type of release
                                   and chemical exposure guideline. Or display DOT ERG2000 values (green pages).

                                   Chemical and Physical  properties such as flash point, boiling point, LEL, UEL, auto ignition
                                   temp, melting point, vapor pressure, vapor density, published toxicity levels, etc.
Proprietor

Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
Specific Chemical Protective Clothing information from manufacturers
NFPA hazard Identification system (NFPA 704 - Standard System for the Identification of
Fire Hazards of Materials)
NIOSH Guidebook respirator recommendations
Synonyms list
Access to procedures and recommendations for 62 chemical classes from DOT ERG-2000
Guide information (orange pages)
(description from website)

Technical Support Working Group

Aristatek, Inc. of Laramie, Wyoming developed the PEAC-CW system. The PEAC-CW
system is available directly from Aristatek or its distributors by calling toll-free 1-877-912-
2200 or fax 307-721-2337.  Software can be purchased separately without a platform or
preloaded on a platform (prices vary depending on platform selected) and quantity discounts
are available. Detailed information is available online at http://www.aristatek.com.

"Published toxicity levels"

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.tswa.aov/subaroups/cbrnc/information-resources/chemical-risk-assessment-
tool.html?KeepThis=true&TB  iframe=true&height=380&width=500
Data Source Name

Identification Number
Data Source Description


Proprietor

Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Pan American Health Organization (PAHO) Communicable Disease

158

Pan American Health Organization (PAHO) has provided an index of data sources and
publications relevant to major communicable diseases in the Americas. It provides links to
surveillance data from PAHO countries.

Pan American Health Organization

Dr. Mirta Roses Periago, Director
Pan American Health Organization
Pan American Sanitary Bureau
Regional Office of the World Health Organization
525 Twenty-third Street, N.W.
Washington, D.C. 20037
United States of America
Country/City Code:  (202)
Tel: 974-3000
Fax: 974-3663

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on  microbial contaminants.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.
                                                        A4-107

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Retrievability Explanation

Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.paho.org/Selection.asp?SEL=TP&LNG=ENG&CD=BDISPRVCT
Data Source Name
Identification Number

Data Source Description
Proprietor
Contact Information

Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
Permit Compliance System (PCS) Database

161

The Permit Compliance System (PCS) provides information on companies which have been
issued permits to discharge waste water into rivers. You can review information on when a
permit was issued and expires, how much the company is permitted to discharge, and the
actual monitoring data showing what the company has discharged. The Water Discharge
Permits Query allows you to retrieve preselected data from the PCS database in
Envirofacts. You can narrow your search by selecting various options including facility
name, geographic location, standard industrial classification, and chemicals. You may also
use the PCS Customized Query to retrieve data and design a query for your particular
needs, using any data element available from the Envirofacts Warehouse. Customized
Queries are primarily geared toward more experienced users.  There is also information on
related laws and regulations, (description from website)

EPA OECA

Users can contact EPA using email form located at:
http ://www. epa.gov/envi ro/ht m l/pcs/pcs_feedback. htm I

Facility, Address, Activity Status, Permit Type, Issued Date, Expired Date, USGS Hydro
Basin, Stream Segment, Flow, Receiving Stream Class, Federal_grant_ind, Receiving
Waters, Final Limits Ind Pretreatment Code, Sludge Information, Permit Documents,
Inspections, Outfalls/pipe Schedules, Limits Report, Measurements and Violations,
Compliance Schedules and Violations, Evidentiary Hearings, Pretreatment

This source is considered relevant  for the CCL Universe because it contains information on
discharge of waste to rivers, which may indicate potential occurrence.

It meets considerations because it  is peer reviewed.

This source is not redundant.

Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.

http://www.epa.gov/enviro/html/pcs/index.html
Data Source Name

Identification Number

Data Source Description
Persistent, Bioaccumulative, and Toxic Profiles (PBT Profiler)

160

The PBT Profiler was designed to be an easy to use, widely available, no-cost tool to screen
chemicals lacking experimental data in order to help identify pollution prevention (P2)
opportunities. It is a continuation of the Office of Pollution Prevention and Toxics (OPPT,
U.S. Environmental Protection Agency) Pollution Prevention (P2) Assessment Framework - a
collection of screening models and methods to help promote the design, development, and
application of safer chemicals and processes. The P2 Framework uses computerized
methods, such as structure/activity relationships (SARs) and standard scenarios, to predict
risk related data (physical/chemical properties, bioconcentration, environmental fate,
carcinogenicity, toxicity to aquatic organisms, worker and general  population exposure, and
other information) on chemicals lacking experimental data. The PBT Profiler arose from
experience gained in the P2 Framework's outreach program, a vigorous set of initiatives by
collaborators in the business, government, and academic sectors to promote the voluntary
use of these tools to reduce pollution and highlight the potential economic benefits of
informed environmental decision making.

The PBT Profiler uses a subset of P2 Assessment Framework computer-based tools to help
identify chemicals that potentially may persist, bioaccumulate, and be toxic to aquatic life,
                                   i.e., PBT chemicals. The release of even small amounts of persistent, bioaccumulative, and
                                   toxic chemicals to the environment is of concern because they can accumulate over time to

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Proprietor

Contact Information
 higher concentrations and, therefore, have a higher potential to adversely impact human
health and the environment. The overwhelming majority of known chemical substances do
not have experimental persistence, bioaccumulation, and toxicity data available. Only a
small fraction of chemicals currently in commerce, including the 2,000 new chemicals
introduced each year, have sufficient data available to perform a thorough evaluation of
potential risks. The PBT Profiler was designed to help interested parties voluntarily screen
chemicals for persistence, bioaccumulation, and aquatic toxicity characteristics when no
experimental data are available, (description from website)

EPA (OPPT), Environmental Science Center, Syracuse Research Corporation

Jay L Tunkel, Ph.D.
Project Manager
Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Predicted persistence (half life) in air, water, soil, and sediment, Bioaccumulation (BCF), Fish
 ChV, Includes structural information

This source is considered relevant for the CCL Universe because it could be a source of
information on persistence, providing an indicator of occurrence.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria. The source does not contain data; it is a
model that might be used to generate estimates.

http://www.pbtprofiler.net/default.asp
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Pesticide Action Network (PAN) Pesticide Database

159

The PAN Pesticide Database brings together a diverse array of information on pesticides
from many different sources, providing human toxicity (chronic and acute), ecotoxicity and
regulatory information for about 6,400 pesticide active ingredients and their transformation
products, as well as adjuvants and solvents used in pesticide products.

This database of active ingredients has been integrated with information in the U.S. EPA
product databases, which provide information on formulated products (the form of the
pesticide that growers and consumers purchase for use) containing the  active ingredients.
The information is most complete for pesticides registered for use in the United States.
(description from website)

Pesticide Action Network

Pesticide Action Network North America
49 Powell St., Suite 500
San Francisco, CA 94102
USA

Phone:(415)981-1771
Fax:(415)981-1991

Email addresses:
panna@panna.org (general comments)
net-admin@panna.org (comments on our online work)

Chemical Name, CAS Number, U.S. EPA PC Code, CA DPR Chem Code, Molecular Weight,
 Use Type, Chem Class, Route of Exposure, Symptoms, First Aid, PAN Bad Actor
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Chemical, Acute Toxicity, Carcinogen, Cholinesterase Inhibitor, Ground Water Contaminant,
Developmental or Reproductive Toxin, Endocrine Disrupter

This source is considered relevant for the CCL Universe because it contains health effects
data.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
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Source URL
http://www.pesticideinfo.org/
Data Source Name

Identification Number

Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Pesticide Data Program

265

The Pesticide Data Program (POP) is a national pesticide residue database program.
Through cooperation with State agriculture departments and other Federal agencies, POP
manages the collection, analysis, data entry, and reporting of pesticide residues on
agricultural commodities, with an emphasis on those commodities highly consumed by
infants and children, (description from website)

US DA

POP Staff:
Agricultural Marketing Service
Science & Technology, Monitoring Programs Office
8609 Sudley Road, Suite 206
Manassas, VA 20110
     Director:  Martha Lament
     Phone: (703) 330-2300 ext. 17 Fax: (703) 369-0678

     Deputy Director:  Diana Haynes
     Phone: (703) 330-2300 ext. 34  Fax: (703) 369-0678

Total Samples Analyzed, Samples with Residues Detected, Percent of Samples with
Detections, Different Pesticides Detected, Different Residues Detected, Total Residue
Detections, % of Samples with Detects, Minimum Value Detected,ppm, Maximum Value
Detected,ppm, Number of Detections of Pesticides in Drinking Water, Pesticides Detected
Above Limit of Quantification in Drinking Water

This source is considered relevant for the CCL Universe because it contains measurements
of pesticide residues, an indicator of potential occurrence.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source meets retrievability criteria because it  is in tabular format.

http://www.ams.usda.gov/science/pdp/index.htm
Data Source Name
Identification Number

Data Source Description
Pesticide Data Sheets (PDS) - WHO, FAO

162

Pesticide Data Sheets (PDSs) contain basic information for safe use of pesticides. The
Pesticide Data Sheets are prepared by WHO in collaboration with FAO and give basic
toxicological information on individual pesticides.  Priority for issue of PDSs is given to
substances having a wide use in public health programmes and/or in agriculture, or having a
high or an unusual toxicity record.  The data sheets are prepared by scientific experts and
peer reviewed.  The comments of industry are provided through the industrial association,
Proprietor
Contact Information
Type of Data Elements
GIFAP. The data sheets are revised from time to time as required, (description from
website)

World Health Organization, Food and Agriculture Organization

The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca

Absorption route, Additional Regulations Recommended, Agriculture, Horticulture and
Forestry, Carcinogenicity, Decontamination Of Spillage And Containers, Dietary studies,
Disposal And/Or Decontamination Of Containers, Emergency Aid, Entry Of Persons Into
Treated Areas, Excretion products, Handling, Household Use, Labelling,  Laboratory Methods,
 Medical Diagnosis and Treatment in Cases of Poisoning, Mode of action, Precautions in
Use, Public Health  Programmes, Recommended Restrictions on Availability, Residues in
Food and Water, Selected Properties, Selection, Training and  Medical Supervision of

                      A4-110

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Relevance Explanation

Redundancy Explanation

Retrievability Explanation

Source URL
Workers, Surveillance Tests, Susceptible pests, Toxicity - Non-Mammalian Species,
Toxicity, Repeated Dose, Toxicity, Single Dose, Toxicology - Mammals, Toxicology - Man,
Transportation and Storage, Unintended Effects, Use Pattern

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

This source is redundant, as it is wholly available as part of INTOX (source 105).

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.inchem.org/paaes/pds.html
Data Source Name

Identification Number

Data Source Description
Proprietor
Contact Information
Type of Data Elements
Pesticide Data Submitters List (PDSL)

266

The Pesticide Data Submitters List is a compilation of names and addresses of registrants
who wish to be notified and offered compensation for use of their data. It was developed to
assist pesticide applicants in fulfilling their obligation as required by sections 3(c)(1)(f) and
3(c)(2)(D) of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and 40 CFR
Part 152 sub part E regarding ownership of data used to support registration.

All pesticides sold or distributed in the United States must be registered by EPA, based on
scientific studies showing that they can be used without posing unreasonable risks to people
or the environment. When applying for registration of a pesticide product, a registrant may
develop and submit the required data, cite all previously submitted data, or cite selected
data. When an applicant cites data previously submitted by another pesticide registrant, the
applicant must make a valid offer to pay compensation to the owner of that data. The Data
Submitters List contains the names and addresses  of companies who submitted data relating
to certain pesticide chemicals who wish to receive such offers, (description from website)

EPA, Office of Pesticide Programs

John Jamula
jamula.john@epa.gov
Information Resources and Services Division
Office of Pesticide Programs (7504C)
Environmental Protection Agency
401 M Street SW
Washington, DC 20460
Ph: 703-305-6426
Fax: 703-305-7670

Chemical Name, Company #, Data Types
Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
This source does not meet relevance criteria because it contains a chemical list that is not
related to health effects or occurrence.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is redundant with NPIRS (source 261); however, NPIRS is a subscription source.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.epa.gov/opppmsd1/DataSubmittersList/
Data Source Name

Identification Number
Data Source Description
Pesticide Ecotoxicity Database

257

Over the last 30 years, pesticide registrants or manufacturers have submitted thousands of
ecotoxicity studies to support the registration or approval of their pesticide products.
Ecotoxicity studies measure the effects of chemicals on fish,  wildlife, plants, and other wild
organisms.

EPA has reviewed these studies according to criteria outlined in their Standard Evaluation
Procedures Manuals and testing methods accepted by the scientific community. After
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Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
reviewing these studies, EPA scientists have determined if they are acceptable for use in
the regulatory process.

In 1991, EPA began electronically summarizing acceptable studies and has now entered over
 15,000 summary records for about 680 pesticide active ingredients into a computerized
database called the Pesticide Ecotoxicity Database.

These summary records include endpoints measurements such as the LD50 (the amount or
dose of a chemical which kills 50% of the exposed animals) and the NOEL or No Observed
Effect Level (the highest concentration of a chemical in a toxicity test that has no
significant adverse effect on the exposed population of test animals).

Although most of the toxicity information in this database was compiled from actual studies
conducted by commercial laboratories, the database also contains acceptable studies
conducted by EPA, USDA, and the Fish and Wildlife Service laboratories and published  data
which meets the Agency's guideline testing requirements.

The Pesticide Ecotoxicity Database  is written in DBase III+ and contains 32 fields per record
entry. Each record entry summarizes one ecotoxicity study for one species whether it is in a
 single species study or a multiple species study, (description from website)

EPA

Brian Montague at Montague.Brian@epa.gov or call 703-305-6438

LD50, NOEL

This source does not meet relevance criteria because it contains only information on
ecological toxicity.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.epa.aov/oppefed1/general/databasesdescription.8-15
Data Source Name
Identification Number
Pesticide Handler Exposure Database
262
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
The Pesticide Handler Exposure Database (PHED) is a database containing voluntarily
submitted empirical exposure data for workers involved in the handling or application of
pesticides in the field; it currently contains data for over 2000 monitored exposure events.
The basic assumption underlying the system is that exposure to pesticide handlers can be
calculated generically, based on the available empirical data for chemicals, as worker
exposure is primarily a function of the formulation type and the handling activities (e.g.,
packaging type, mixing/loading/application method, and clothing scenario),  rather than
chemical-specific properties, (description from website)

EPA

Alan Dixon at dixon.alan@epa.gov or call 703-305-7237 for assistance.

Pesticide exposure data

This source is considered relevant for the CCL Universe because it contains information on
human exposure to pesticides.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.

http://www.epa.gov/pesticides/science/models db.htm
                                                         A4-112

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Data Source Name

Identification Number
Data Source Description
Proprietor

Contact Information
Type of Data Elements


Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Pesticide Product Information System (PPIS)

168

The database contains information concerning all pesticide products registered in the United
States. Information in the data set for each pesticide includes registrant name and address,
chemical ingredients and CAS registry numbers, toxicity category (i.e., danger, warning, and
caution), product names, distributor brand names, site/pest uses, pesticidal type, formulation
 code, and registration status. The data are available from a list of zipped ascii files.

EPA

Jim Beech
beech.james@epa.gov
EPA Office of Pesticide  Programs
Ariel Rios Building
1200 Pennsylvania Avenue, N. W.
Mail Code: 7502P
Washington, DC 20460

Name, CASRN, Registrant name and address, Chemical ingredients, Toxicity category,
Product names, Distributor brand names, Site/pest uses, Pesticidal type, Formulation code,
and Registration status

This source is considered relevant  for the CCL Universe because it contains an indicator of
possible health effects.

It meets considerations  because it  meets all NDWAC minimum data requirements.

This source is redundant with NPIRS (source  261); however,  NPIRS is a subscription source.

Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.

http://www.epa.aov/opppmsd1/PPISdata/index.html
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Pesticide Product Label System (PPLS)

267

The Pesticide Product Label System is a collection of images, in multi-page TIFF format, of
pesticide labels which have been approved by the Office of Pesticide Programs (OPP) under
 Section 3 of the Federal Insecticide, Fungicide, and Rodenticide Act. The collection contains
 the initially approved label for pesticide products registered under FIFRA Section 3 as well
as subsequent versions of labels which have changed via amendment or notification.

In addition to the stamped approved labels this collection contains any associated
correspondence about the terms of registration, specifying any changes which the registrant
was required to make in the final printed label. Because some label amendments address
only portions of the label, you may have to review several labels for a single product to
determine the complete terms of registration.

The collection does not identify those products which have been subsequently canceled or
transferred, but rather identifies each pesticide label as it appeared at the time that it was
approved. In additon, please review Limitations of the Pesticide Product Label System.

The label images are indexed by EPA registration number and the date on which the label was
 initially registered or amended. If you do not know the registration number, you can search
all federally registered products by active ingredient, product name, or company name, in
EPA's Pesticide Product Information System,  which you can access on the  California
Department of Pesticide Regulation website at California Department of Pesticide Regulation
 (CDPR).  (description from website)

EPA

John Jamula
jamula.john@epa.gov
Information Resources and Services Division
Office of Pesticide Programs (7504C)
Environmental Protection Agency
401 M Street SW
Washington, DC 20460
                      A4-113

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Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Ph: 703-305-6426
Fax: 703-305-7670

Name; CAS RN; First aid: if swallowed, if on skin or clothing, if in eyes, if inhaled;
Precautionary statements: hazard to humans and domestic animals warning, environmental
hazards, storage and disposal

This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.

http://www.epa.gov/pesticides/pestlabels/
Data Source Name
Identification Number
Data Source Description
Pesticide Products Databases

268

OPP and the California Department of Pesticide Regulation have developed an interactive
database that offers brief registration information on approximately 89,000 products. The
data include: product number and name, company number and name, registration date,
cancellation date and reason (if canceled), and product manager name and phone number.
Also offered are databases containing chemical ingredient information, searchable by
common, technical, synonym, CAS number, or trade names, and firm information,
searchable by firm number or name.
(description from website)
Proprietor
Contact Information
Type of Data Elements
Completeness Explanation
Redundancy Explanation
Retriev ability Explanation

Source URL
This database serves as a gateway to the information contained in the Pesticide Products
Information System (PPIS). The data dictionary for this source is therefore for data
elements found in PPIS.

EPA/Cal EPA

California Department of Pesticide Regulation
1001  I Street, P.O. Box 4015
Sacramento, CA 95812-4015
General Information:
(916)445-4300
FAX: (916) 324-1452

Name, Synonyms, CASRN, Company, Registration Date

It meets considerations because it meets all NDWAC minimum data requirements.

This source is redundant with FIFRA.

This source meets retrievability criteria because the relevant data can be extracted in tabular
format.

http://www.cdpr.ca.gov/docs/epa/epamenu.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Pesticide Tolerance Index System (TISInfo)

269

The Pesticide Tolerance Index contains a complete listing of pesticide tolerances. TISinfo is
an older DOS based system. However, it is the only electronic version of pesticide
tolerances available at this time from the Office of Pesticide Programs. These databases
are downloadable, self-extracting compressed files. The programs TISINDEX.EXE and
TISINFO.EXE can be used to generate indexes for this data and then to search it and
generate reports from it. (description from website)

EPA

Bernie Schneider
                                                       A4-114

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Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
schneider.bernard@epa.gov EPA
Office of Pesticide Programs
Ariel Rios Building
1200 Pennsylvania Avenue, N. W.
Mail Code: 7509P
Washington, DC 20460

Unknown

This source is considered relevant for the CCL Universe because it contains information on
pesticide exposure tolerances.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is redundant with NPIRS (source 261); however, NPIRS is a subscription source.

Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.

http://epa.aov/agriculture/tpes.htmltfTolerances
Data Source Name

Identification Number

Data Source Description
Proprietor

Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retriev ability Explanation
Source URL
Pesticides Ground and Surface Water Incident Database

259

This electronic database was created in 1999 and contains adverse effects data for
aggregate as well as individual pesticides detected in ground and/or surface water incidents.
A water incident is defined as an occurrence of a pesticide in water at any measurable level.
 All of the incident data for this database comes from pesticide manufacturers who are
required to report adverse effects information under section 6(a)(2) of the pesticide law
FIFRA. At the present time, the database contains about 13,200 incident records. Each
record can contain up to 28 fields of information. These water incidents play an important
role in EPA's risk assessment and decision-making process, and are considered in the
Agency's risk assessments for individual pesticides, (description from website)

EPA

Donna Price at Price.Donna@epa.gov or call 703-308-2876

Measurements in water

This source is considered relevant for the CCL Universe because it is being designed to
contain information on pesticide occurrence in water, an indicator of occurrence.

This source has been withdrawn; it is no longer available online.

This source has been withdrawn; it is no longer available online.

This source has been withdrawn; it is no longer available online.

http://www.epa.gov/oppefed1/general/databasesdescription.8-15
Data Source Name

Identification Number
Data Source Description
Pesticides in Ground and Surface Water Database

260

The Pesticides Program in EPA is in the process of developing a database which contains
information on the presence of pesticides in treated as well as untreated ground and surface
water. Information in this database will be provided by the U.S. Geological Survey, the
Office of Water in EPA, the U.S. Department of Agriculture, other federal and state
agencies, registrants or pesticide manufacturers, and other public entities, such as
universities.

The database will have a series of "canned" search and download features as well as the
ability to customize searches and downloads.  In addition, the database will have direct links
to the Office of Water's National Contamination Occurrence Database, STORET, and other
occurrence databases.

After the release of the first version (Release 1), OPP will be populating the database with
other sources of data, such as the Pesticide in Ground Water Database, registrant submitted
                                                        A4-115

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Contact Information

Type of Data Elements
Relevance Explanation
 ground and surface water studies, state monitoring programs, and other readily accessible
sources of data.

OPP plans to use the information in this database in developing risk assessments for water
resources, (description from website)

EPA

Sid Abel at Abel.Sid@epa.gov or call 703-305-7346

Occurrence Concentrations (database is under development)

This source is considered relevant for the CCL Universe because it is being designed to
contain information on pesticide occurrence in water, an indicator of occurrence.
Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
This source has been withdrawn; it is no longer available online.

This source has been withdrawn; it is no longer available online.

This source has been withdrawn; it is no longer available online.

http://www.epa.aov/oppefed1/general/databasesdescription.8-15
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retriev ability Explanation

Source URL
Pesticides Pilot Monitoring Program - USGS/EPA

164

In 1999, a pilot monitoring program was initiated by EPA and USGS to provide information on
 pesticide concentrations in drinking water and to assist in the implementation of the Food
Quality Protection Act (FQPA) of 1996. Twelve water-supply reservoirs were sampled, in
California, Indiana, Ohio, Oklahoma, Louisiana, Missouri, South Carolina, South Dakota, New
 York, North Carolina, Pennsylvania, and Texas.  Sampling frequencies were designed to
measure long-term mean and short-term peak concentrations of pesticides in drinking water.
 The sampling methods included 178 different pesticides and degradation products. The
results of the program were later incorporated in EPA's revised Organophosphate Pesticide
Cumulative Risk Assessment,  (description from website)

EPA Office of Ground Water and Drinking Water and USGS NAWQA

Joel Blomquist
U.S. Geological Survey WRD
8987 Yellow Brick Road
Baltimore, Maryland 21237
E-Mail: jdblomqu@usgs.gov
Phone:(410)238-4260
Fax:(410)238-4210

Drinking Water Occurrence Concentrations

This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because the relevant data can be extracted in tabular
 format.

http://md.water.usgs.gov/nawga/abstract.html
Data Source Name

Identification Number
Data Source Description
Plant Toxicity Data

280

PHYTOTOX contains records relating to the biological effects of the application of organic
chemicals to terrestrial plants. Both natural and synthetic organic compounds administered to
 native, crop, or weed plant species have been included. The records include data on effects
 and on the corresponding scientific source papers.
                                  SUBJECT COVERAGE:
                                                       A4-116

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                                   Chemical Name Identification
                                   CAS Registry Numbers
                                   Bibliographic References
                                   Biological Effects
                                   Test Conditions
                                   Application Procedures
                                   (description from website)
Proprietor
Contact Information
Type of Data Elements



Relevance Explanation

Completeness Explanation

Redundancy Explanation

Retrievability Explanation

Source URL
National Information Services Corporation (NISC)/EPA

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

CAS RN, Chemical Name, Stage at application, Stage at recording, Condition at application,
Site of application, Maintenance of plant, Physical state of chemical, Route/method,
Dosage, Effects data, Test Duration, Study grade, Species identification, Source/journal,
Reference number, Author, Publication year, Title

This source does not meet relevance criteria because it contains only information on plant
toxicity.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is redundant with ECOTOX (source 57).

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.nisc.com/cis/details/phvtotox.htm
Data Source Name

Identification Number

Data Source Description
Proprietor

Contact Information



Type of Data Elements


Relevance Explanation

Completeness Explanation
Poisons Information Monographs (PIMs) - IPCS, CCOHS

165

PIMs are part of a global database with evaluated information on substances (chemicals,
Pharmaceuticals, poisonous plants, and poisonous and venomous animals) commonly
involved in cases of poisoning. A PIM is a concise, practical document designed to facilitate
the work of poisons information specialists, clinicians, and analysts.

The PIM is more than a simple monograph and part of a database. It is a dynamic document
which represents an international consensus on the diagnosis, management and prevention
of poisonings. It may also constitute the basis for training, a source of scientific reference
and a stimulus for international cooperation amongst poisons centres and clinical toxicology
units around the world.

The PIMs are prepared by collaborating poisons information centres and other experts
throughout the world and are subjected to individual and peer review.  PIMs summarize the
physico-chemical and toxicological properties of the substance, the medical features of the
effects produced by various routes of exposure to the substance, the patient management
and the supporting laboratory investigations, (description from website)

International Programme for Chemical Safety, Canadian Centre for Occupational Health and
Safety, Worldwide Poison Information Centers

The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca

Name, Formula, Synonyms, CASRN, ID numbers, MW, Density, BP, MP, Water Solubility,
Other Solubility, Partition Coefficients, Log Koc, Log Kow, VP, HLC, ADI, MAK, PEL, STEL,
TWA, LCx, LDx, NO(A)EL, LO(A)EL

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.
                     A4-117

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EPA815-R-09-006
      August 2009
Redundancy Explanation
This source is redundant, as it is wholly available as part of INTOX (source 105).
Retrievability Explanation

Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.inchem.ora/pages/pims.html
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
POLLUAB - Pollution Abstracts

166

POLLUAB is a bibliographic database which contains information on water and air pollution,
sources, and pollution control. The database contains both scientific research and
government policy literature on environmental information, including toxicology and health.
Sources are books, conference proceedings, journals, nontechnical literature,  research
reports, and file data from 1981 to the present, with over 195,000 literature references.
(description from website)

Cambridge Scientific Abstracts

Cambridge Scientific Abstracts
7200 Wisconsin Avenue
Bethesda, MD 20814 USA
Voice: 800-843-7751  (in N. America)
Voice: +1 301-961-6700 (worldwide)
Fax:+1 301-961-6720
Email: sales@csa.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated  retrieval.

http://www.cas.org/ONLINE/DBSS/polluabss.html
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation
Pollution Prevention Research and Development Database -
EnviroNET Australia

167

Australia's EnviroNET is a directory of Australia's environment industries including databases
of environment management expertise, industry applications for environmental
technologies, environmental education; plus a range of other resources to support
development and uptake of Australian solutions to industry's environmental issues.
(description from database)

Environment Australia

www.environment.gov.au

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
Completeness Explanation
It does not meet considerations because there was no documentation on how the data were
obtained.
                                                       A4-118

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         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Redundancy Explanation
Retrievability Explanation

Source URL
This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.erin.gov.au/net/environet
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
Preliminary Remediation Goals (PRGs) - EPA Region 9

169

Preliminary Remediation Goals (PRGs) are tools for evaluating and cleaning up  contaminated
sites. They are risk-based concentrations that are intended to assist risk assessors and
others in initial screening-level evaluations of environmental measurements. The PRGs
contained in the Region 9 PRG Table are generic; they are calculated without site specific
information. However, they may be re-calculated using site specific data.

PRGs should  be viewed as Agency guidelines, not legally enforceable standards. They are
used for site "screening" and as initial cleanup goals if applicable. PRGs are not de facto
cleanup standards and should not be applied as such. However, they are helpful in providing
long-term targets to use during the analysis of different remedial alternatives. By developing
PRGs early in the decision-making process, design staff may be able to streamline the
consideration  of remedial alternatives, (description from website)

EPA Region 9

United States Environmental Protection Agency
REGION IX
75 Hawthorne Street
San Francisco, CA 94105
smucker.stan@epa.gov

PRGs, RfD, Slope Factor, Cancer Risk

This source is considered relevant for the CCL Universe because it contains data elements
derived from toxicological studies.

It meets considerations because it is peer reviewed.

The relevant data in this source are redundant with ITER and IRIS.

This source meets retrievability criteria because it is in tabular format.

http://www.epa.gov/region09/waste/sfund/prg/index.htm
Data Source Name

Identification Number
Data Source Description
Proprietor
Priority Substances Assessment Program - Health Canada

170

The Canadian Environmental Protection Act (CEPA) requires the establishment of a Priority
Substances List (PSL). Substances on this List are of priority for assessment to determine
whether environmental exposure to them poses a risk to the health of Canadians or to the
environment. A Priority Substance may be a chemical, a group of chemicals, effluents or
wastes. There have been two PSLs (PSL1 and PSL2),which were established by the Ministers
of Health and of the Environment, based on the recommendations of a Ministers' Expert
Advisory Panel,  (description from website)

Health Canada
Contact Information
Inquiry Centre
351 St. Joseph Blvd
Hull, Quebec
K1AOH3
1-800-668-6767
To obtain an electronic version of the Assessment Report in PDF, please request a copy
from the following address: PSL.LSIP@ec.gc.ca
                                  Name, Synonyms, CASRN, Formula, BMC, BMD, ENEV, MTD, CTV, ECx, ICx, LDx,

                                                       A4-119

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        Final CCL 3 Chemicals:
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EPA815-R-09-006
      August 2009
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.ec.ac.ca/substances/ese/eng/psap/final/main.cfm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Priority-based Assessment of Food Additives (PAFA) Database

157

PAFA contains over 3,000 "indirect food additives." It is a list of substances mentioned in
Title 21 of the U.S. Code of Federal Regulations, Parts 175, 176, 177, and 178. "Indirect
food additives" include substances used in "food-contact articles, and include adhesives and
components of coatings, paper and paperboard components, polymers, and adjuvants and
production aids."  (description from website)

FDA Center for Food Safety and Applied Nutrition

C.H.I.P.S.
10777 Mazoch Road
Weimar, Texas 78962
Phone (979) 263-5683
Fax (979) 263-5685
http://www.chipsbooks.com/questions.htm

Genetic Toxicity and Cytotoxicology, Acute Toxicology, Oral Toxicology, HNEL,
Toxicological effect, Exposure, ADI, LD High, LEL

This source is considered relevant for the CCL Universe because it contains data elements
directly from and derived from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1568244&blobtype=pdf
Data Source Name
Identification Number
Data Source Description
Program for Monitoring Emerging Disease (ProMED)

171

ProMED tracks reports of emerging disease in the media and in the medical literature. The
web site offers a variety of information, including archives of ProMED mail, web links, and
other resources concerning emerging diseases, (description from website)
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Federation of American Scientists

ProMED
1717KSt.,NW
Suite 209
Washington, DC 20036
Voice: (202) 546-3300
Fax:(202)675-1010
E-mail: dpreslar@fas.org

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
Completeness Explanation      It meets considerations because it is peer reviewed.
                                                      A4-120

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        Final CCL 3 Chemicals:
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      August 2009
Retrievability Explanation

Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.fas.org/promed/
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
PubMed

172

PubMed is a searchable citation and abstract generator for over 4,500 peer reviewed
biomedical journals from the mid-1960s to the present. This bibliographic database is useful
for primary literature on health effects for all types of contaminants,  (description from
website)

National Library of Medicine, NCBI, NIH

U.S. National Library of Medicine
8600 Rockville Pike
Bethesda, MD 20894
email: custserv@nlm.nih.gov

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www4.ncbi.nlm.nih.gov/PubMed/
Data Source Name
Identification Number
PulseNet: The National Molecular Subtyping Network for Foodborne
Disease Surveillance
173
Data Source Description


Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Source URL
PulseNet is a network of public health laboratories that identify food-borne pathogens to the
molecular level using pulse-field gel electrophoresis. Isolated organism "fingerprints" are
compared to determine if food poisoning has a common source, (description from website)

CDC

Centers for Disease Control and Prevention
1600 Clifton Rd
Atlanta, GA 30333, U.S.A
Tel: (404) 639-3311
Public Inquiries: (404) 639-3534 / (800) 311-3435

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

http://www.cdc.gov/pulsenet/what  is.htm
                                                      A4-121

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         Final CCL 3 Chemicals:
         Identifying the Universe
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      August 2009
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Registry of Toxic Effects of Chemical Substances (RTECS)

180

The Registry of Toxic Effects of Chemical Substances (RTECS®) is a database of
toxicological information compiled, maintained, and updated by the National Institute for
Occupational Safety and Health. The program is mandated by the Occupational Safety and
Health Act of 1970. The original edition, known as the "Toxic Substances List," was published
on June 28, 1971, and included toxicologic data for approximately 5,000 chemicals. Since
that time, the list has continuously grown and been updated, and its name changed to the
current title, "Registry of Toxic Effects of Chemical Substances." As of May 2003, the last
update of the database by NIOSH, RTECS contained 156,485 chemicals as NIOSH strived
to fulfill the mandate to list "all known toxic substances... and the concentrations at  which...
toxicity is known to occur."

RTECS® is a compendium of data extracted from the open scientific literature. The data are
recorded in the format developed by the RTECS® staff and arranged in alphabetical order
by prime chemical name. No attempt has been made to evaluate the studies cited in
RTECS®. The user has the responsibility of making such assessments.

RTECS® provides:  access to toxicity information for 156,485 chemicals; identification of six
types of toxicity data including: primary irritation, mutagenic effects, reproductive effects,
tumorigenic effects, acute toxicity, other multiple dose toxicity; and includes specific
numeric toxicity values such as LD50, LC50, TDLo, TCLo, and identification of species
studied and route of administration used. Each data line lists the bibliographic source to
indicate actual studies cited,  (description from website)

CDC National Institute for Occupational Safety and Health (NIOSH)

The Editor
Registry  of Toxic Effects of Chemical Substances
MDL Information Systems, Inc.
200 Wheeler Road, 6th Floor
Burlington, Massachusetts U.S.A. 01803
FAX: (781) 272-6868
Distributor of RTECS: Canadian Centre for Occupational Health and Safety
135 Hunter Street East
Hamilton, ON,  Canada L8N 1M5
To order: 1-800-668-4284
General  Requests: clientservices@ccohs.ca
Technical Support: technicalsupport@ccohs.ca
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
LDx, NOAEL, LOAEL, Reproductive/ Developmental, Mutation, Irritation, Tumorigenic data

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.cdc.aov/niosh/rtecs/RTECSaccess.html
Data Source Name

Identification Number

Data Source Description
Proprietor

Contact Information
Reregistration Eligibility Decision Documents (REDDs) - EPA OPP

176

"When EPA completes the review and risk management decision for a pesticide that is
subject to reregistration (i.e., one initially registered before November 1984), EPA generally
issues a Reregistration Eligibility Decision (RED) document. The RED summarizes the risk
assessment conclusions and outlines any risk reduction measures necessary for the
pesticide to continue to be registered in the U.S."  There are REDs for over 176 pesticides
currently, (description from website)

EPA Office of Pesticide Programs

Special Review and Reregistration Division (7508W)
US Environmental Protection Agency
Office of Pesticide Programs

                     A4-122

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EPA815-R-09-006
      August 2009
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Washington, DC 20460
Telephone 703-308-8000

Name, Synonyms, DWLOC, PAD, RfD, MCL, SF, LCx, LDx, LO(A)EL, MOE, NO(A)EL,
HOT

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.epa.aov/pesticides/reregistration/status.htm
Data Source Name
Identification Number
Data Source Description
Resource Conservation and Recovery Information System

275

RCRIS provides comprehensive information on all RCRA hazardous waste handlers in the
US and its territories. These waste handlers include large- and small-quantity generators,
transporters, burner/blenders, incinerators, and TSD facilities.
                                  SUBJECT COVERAGE:
                                  Facility Location and Identification Data
                                  Handler Classification
                                  Source and Activity Data
                                  Permit Application Data
                                  (description from website)
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
National Information Services Corporation (NISC)

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax:  +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Name, Address, River basin codes, Ownership type, Quantity and type of hazardous waste
produced, Types of operations conducted at a site

This source does not meet relevance criteria because it does not contain health effects or
occurrence data or information.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.nisc.com/cis/details/rcris.htm
Data Source Name


Identification Number
Data Source Description
Rijksinstituut voor Volksgesondheid en Milieu (RIVM) Maximum
Permissible Risks (MPRs) Report

179

Soil Intervention Values are generic soil quality standards based on potential risks to humans
and eco-systems. These values are used to determine whether or not contaminated soils
meet the criteria for "serious soil contamination" as stated in the Dutch Soil Protection Act.
With reference to potential risks to humans, Maximum Permissible Risk (MPR) values,
quantifying the human-toxicological risk limits for some 50 chemicals and chemical classes,
                     A4-123

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Proprietor

Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
were derived in the 1991-1993 period. These MPRs, which have since been updated,
comprise limits on tolerable daily intake, tolerable concentration in air, and oral cancer risk
and/or inhalation cancer risk. In total, the compounds comprise 12 metals (including
cadmium, lead and mercury),  10 aromatic compounds (including the polycyclic aromatics),
13 chlorinated hydrocarbons (including dioxins and polychlorinated biphenyls), 6 pesticides
(including DDT) and 7 other compounds (including cyanides and total petroleum
hydrocarbons). A toxicity profile has been compiled for each compound or compound class.
It consists of a concise summary of the available toxicity data, information on back-ground
exposure and a survey of existing limit values derived by other organisations. An updated
MPR for each compound (or class of compounds) in question is deduced from the
respective profile, (description from website)

Rijksinstituut voor Volksgesondheid en Milieu (RIVM), The Netherlands

RIVM
PO Box 1
3720 BA Bilthoven
The Netherlands

Absorption Factors, ADI, Backgrnd Exposure, CR, Crinhal reliability, Crinhal value, Croral
reliability, Croral value, Dose Ranges, HUM-TOX SCO, IARC Cancer Group, LO(A)EL, MAC,
MPR: oral, inhalation, MRL, MTD, NO(A)EL, Old MPR?, pCRinhal reliability, pCRinhal value,
pCRoral reliability, pCRoral value, Production/Use, pTC(A), pTCA reliability, pTCA value,
pTDI, pTDI reliability, pTDI value, Reliability, TC(A), TCA reliability, TCA value, TD(i/o/lo),
TDI High value, TDI Low value, TDI low/high reliability, TDI reliability, TDI Value, Uncertainty
 Factors, WQG

This source is considered relevant for the CCL Universe because it contains data elements
from  toxicological studies.

It meets considerations because it is peer reviewed.
Redundancy Explanation

Retrievability Explanation

Source URL
This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.rivm.nl/en/
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Risk Assessment Information System (RAIS) - Department of
Energy - Chemical Factors

177

This database of chemical-specific factors (i.e., chemical properties) contains values needed
 in the human health risk assessment exposure equations to calculate dose or in the human
health risk-based preliminary remediation goal (PRG) equations to calculate the chemical-
specific risk-based PRGs. This database contains information taken from a variety of
sources, and these sources are referenced. If a user needs additional information about the
application or contents of this database, please contact the Center for Risk Excellence at
risk.center@ch.doe.gov.  (description from website)

U.S. Department of Energy

Fred Dolislager
University of Tennessee
1060 Commerce Park Drive, MS 6480
Oak Ridge, TN 37830
Phone: (865) 482-5304
E-mail: fdolislager@utk.edu

Name, CASRN, Absorption factor, beef transfer coefficient, BP, Soil to Plant dry uptake,
Soil to Plant wet uptake,  Diffusivity in air, Diffusivity in water, Fish bioaccumulation factor,
Gl absorption factor, Gl absorption fraction, Radioactive half life, Soil-water partition
coefficient, Koc, Kp, log Kow, ICRP lung type, milk transfer coefficient, MP, MW, water

This source is considered relevant for the CCL Universe because it contains radioactive
half-life data, providing an indicator of occurrence.

It meets considerations because it is peer reviewed.

This source is not redundant.
                                                         A4-124

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      August 2009
Retrievability Explanation

Source URL
This source meets retrievability criteria because the relevant data can be extracted in tabular
format.

http://risk.lsd.ornl.gov/rap hp.shtml
Data Source Name


Identification Number
Data Source Description
Risk Assessment Information System (RAIS) - Department of
Energy - Health Effects Data

178

This database of chemical-specific toxicity values contains the human health toxicological
information needed to perform risk evaluations and assessments. This database contains
toxicity information taken from the United States Environmental Protection Agency's (EPA)
Integrated Risk Information System (IRIS), the Health Effects Assessment Summary
Tables (HEAST), and other sources. In this database, all information is referenced.
Additionally, the database contains supplemental information which clarifies some issues.
The database of chemical-specific toxicity metadata contains values needed in human
health toxicity assessments. This database contains information taken from
IRIS/HEAST/NCEA, and these sources are referenced. If a user needs additional information
about the application or contents of this database, please contact the Center for Risk
Excellence at risk.center@ch.doe.gov. (description from website)
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
U.S. Department of Energy

Fred Dolislager
University of Tennessee
1060 Commerce Park Drive, MS 6480
Oak Ridge, TN 37830
Phone: (865) 482-5304

RfD (critical effect), RfC, Slope Factor, Unit Risk, Absorption Factor, Cancer Class

This source is considered relevant for the CCL Universe because it contains data elements
directly from and derived from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because the relevant data can be extracted in tabular
format.

http://risk.lsd.ornl.gov/rap hp.shtml
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Risk Based Concentrations (RBCs) - EPA Region 3

175

The RBC Table contains Reference Doses (RfDs) and Cancer Slope Factors (CSFs) for 455
chemicals. These toxicity factors have been combined with "standard" exposure scenarios
to calculate RBCs - chemical concentrations corresponding to fixed levels of risk (i.e., a
Hazard Quotient (HQ) of 1, or lifetime cancer risk of 1E-6, whichever occurs at a lower
concentration) in water, air, fish tissue, and soil. The equations and the exposure factors are
shown in the RBC Table companion memo, the Technical Background Document. The Region
III toxicologists use RBCs to screen sites not yet on the NPL, respond rapidly to citizen
inquiries, and spot-check formal baseline risk assessments. The primary use of RBCs is for
chemical screening during baseline risk assessment (see EPA Regional Guidance
EPA/903/R- 93-001, "Selecting Exposure Routes and Contaminants of Concern by Risk-
Based Screening"). The exposure equations come from  EPAs Risk Assessment Guidance
for Superfund (RAGS), while the exposure factors are those recommended in RAGS or
supplemental guidance from the Superfund program, (description from website, RBC table
cover memo)

EPA Region 3

United States Environmental Protection Agency
REGION III
1650 Arch Street
Philadelphia, Pennsylvania 19103
                     A4-125

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Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
hubbard.jennifer@epa.gov

RBCs, RfD, Slope Factor, SSL

This source is considered relevant for the CCL Universe because it contains data elements
derived from toxicological studies.

It meets considerations because it is peer reviewed.

The relevant data in this source are redundant with ITER and IRIS.

This source meets retrievability criteria because it is in tabular format.

http://www.epa.aov/reg3hwmd/risk/index.htm
Data Source Name
RISKLINE
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
281

This database includes bibliographic records elaborated by informative abstracts dealing with
human and animal toxicology and carcinogenicity. The database was created by the Swedish
 National Chemicals Inspectorate. In some cases, the records relate to publications produced
 by toxicological societies and journals. In the main, however, the records relate to
publications produced by industrial and technical associations, governmental agencies, and
international agencies; heavily represented are the following organizations: IARC, ACGIH,
NCI, BIBRA, EPA, NTP, WHO, and ATSDR.

Users can retrieve records by CAS Registry Number (the preferred method) and/or subject
terms/phrases. More than 4,000 unique chemicals are covered in the database. The earliest
records in the database date from 1970, the latest from 2001.

SUBJECT COVERAGE:
CAS Registry number
Health Hazard Information
Chemical Name
(description from website)

National Information Services Corporation (NISC)/Swedish National Chemicals Inspectorate

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted  for
automated retrieval.

http://www.nisc.com/cis/details/riskline.htm
Data Source Name
Identification Number
Data Source Description
Safe Drinking Water Information System (SDWIS)

232

The Safe Drinking Water Information System (SDWIS) contains information about public
water systems and their violations of EPA's drinking water regulations, as reported to EPA
                                                       A4-126

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Proprietor
Contact Information
by the states. These regulations establish maximum contaminant levels, treatment
techniques, and monitoring and reporting requirements to ensure that water systems provide
safe water to their customers. This queries help find drinking water supplier and view
violations and enforcement history since 1993.

See UCM - Round 2 (SDWIS/FED) - Unregulated Contaminant Monitoring and NCOD -
National Drinking Water Contaminant Occurrence Database - Round 1&2. Some Safe
Drinking Water Information System (EPA) data contained in these data sources.

EPA

Users can contact EPA using the form located at:
http://www.epa. gov/enviro/html/sdwis/sdwis_feedback.htm I
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Water System Name, Principal County Served, Population Served, Primary Water Source
Type, System Status, Water System ID, Concentration, Violations

This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.

http://www.epa.aov/enviro/html/sdwis/index.html
Data Source Name


Identification Number
Data Source Description
Proprietor

Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retriev ability Explanation

Source URL
Screening Information Data Sets (SIDS) - Organisation for Economic
Co-operation and Development (OECD)

182

OECD SIDS contain information collected on 92 chemicals from the HPV chemical list. The
SIDS are produced in a format consistent with IRPTC data files, in order to meet initial
assessment data needs for these chemicals and to generate information that may have
been lacking. SIDS include physicochemical properties, production data, health effects,
analysis effects, use, effects on organisms and ecosystems, environmental fate, and
information on regulatory measures.  These data sets may be useful for gathering
physicochemical property and health effects data, including specific endpoints where
available, for any chemicals on the HPV list, (description from website)

International Programme for Chemical Safety, United Nations Environmental Program;
UNEP/IRPTC in Geneva, Switzerland

UNEP Chemicals
11-13 chemin des Anemones,
CH-1219 Chatelaine
Geneva, Switzerland
Tel: (+41 22) 917 8170 and Fax (+41 22) 797 3460
Email: chemicals@unep.ch

Name, Formula, Synonyms, CASRN, Other IDs, ADI, ECx, LCx, LDx, NO(A)EL

This source is considered relevant for the CCL Universe because it contains data elements
(LDx, NO(A)EL) from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet  retrievability criteria because the data are not formatted for
automated  retrieval.

http://www.chem.unep.ch/irptc/Publications/sidsidex/sidsidex.htm
                                                       A4-127

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Data Source Name

Identification Number
Data Source Description
SOLV-DB

183

SOLV-DB provides health and safety considerations, chemical and physical data, regulatory
responsibilities, and environmental fate data on approximately 325 solvents.  In addition
SOLV-DB provides a list of manufacturers for each solvent, a list of all solvents in the
database available from each manufacturer, the "Chemical Abstracts Service (CAS) number"
for each solvent, the identifying designation "Sax Number" from Sax, et al., Dangerous
Properties of Industrial Materials and a table of synonyms. SOLV-DB is searchable by
solvent name, Chemical Abstracts Number, Sax Number, or chemical formula.  Additional
Proprietor

Contact Information


Type of Data Elements
Relevance Explanation
Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
features for searching include a "Select by Synonym" button to search the database under
another name, a "Select By Chemical Category" button for finding all solvents falling into a
particular chemical family (ketones, aromatic hydrocarbons, CFCs, etc.), a "Select By
Property Range" to find all solvents satisfying a set of criteria, and a  "Select By Matching
Text" button to find solvents whose text descriptions contain a specified character string.

When searching by name, CAS number, or Sax number, one will get a general information
table with the most commonly requested information about a solvent.  Additional tables with
Health and Safety Data, Chemical-Physical Data, Regulatory Data, and Environmental Fata
 Data are also provided. The information tables contain many data elements of specialized
interest, and one may click on the label for each element to retrieve background information
or a definition of the element, (description from website)

National Center for Manufacturing Sciences

Paul Chalmer
National Center for Manufacturing Sciences
paulc@ncms.org , or (734) 995-4911

Name, CASRN, structure,  SMILES, formula, MW, BP, FP, VP, viscosity, specific gravity,
refractive index, dielctric constant, evaporation rate, water solubility, log Kow, HLC,
Hildebrand solubility parameter, pKa, pH, azeotrope, surface tension, vapor density, Kauri-
butanol, flash point, heat capacity,  heat of vaporization, thermal conductivity,  autoignition
temperature, corrosive, color, odor, odor threshold, UV absorption

This source does not meet relevance criteria because it contains only chemical property

It meets considerations because it  meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.

http://solvdb.ncms.org/index.html
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation
Source Ranking Database (SRD)

189

SRD was developed to provide a means for systematically reviewing a large number of
consumer products, building materials, and furnishings that are potential sources of airborne
chemicals to which individuals can be exposed while indoors. According to the web site,
SRD "performs a systematic screening-level review of over 12,000 potential indoor pollution
sources to identify high-priority product and material categories for further evaluation, and
can also identify the products that have contained a specific chemical." (description from
website)

EPA OPPT

Richard Wormell
U.S. Environmental Protection Agency
Office of Pollution Prevention and Toxics
1200 Pennsylvania Avenue N.W. (Mail Code 7406M)
Washington, DC 20460
Phone: (202)564-8538
E-mail: wormell.richard@epa.gov

Unknown

This source is considered relevant for the CCL Universe because it has elements that may
indicate possible occurrence and/or possible health effects.
                      A4-128

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EPA815-R-09-006
      August 2009
Completeness Explanation      It meets considerations because it is peer reviewed.
Redundancy Explanation
Retrievability Explanation

Source URL
 This source is not redundant.

 This source does not meet retrievability criteria. The source does not contain data; it is a
 model that might be used to generate estimates.

 http://www.epa.aov/opptintr/exposure/pubs/srddl.htm
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation

Retrievability Explanation

Source URL
 State Drinking Water Data Sets

 190

 These data sets include public water system contaminant occurrence data sets directly from
 17 States (with data from 1983 to 2000, but primarily covering 1993 to 1997), which include
 the regulated chemical contaminants (particularly the 64 "phase" chemicals) and some States
 contain data for unregulated contaminants. The Cadmus Group, Inc. developed these for
 EPA and currently maintains extensively edited, working versions of these 17 data sets.

 (See National Drinking Water Contaminant Occurrence Database (NCOD) - 6-Year Data.
 Most data from the State Drinking Water Data Sets are contained in this data source.)

 EPA OGWDW; The Cadmus Group, Inc.

 Erin Mateo
 The Cadmus Group
 57 Water Street
 Watertown, MA 02472
 Phone: 617-673-7000

 Drinking water occurrence concentrations

 This source is considered relevant for the CCL Universe because it contains measurements
 of contaminants in water, demonstrating occurrence.  Most data are available for regulated
 contaminants. Some data are available for unregulated contaminants.

 It meets considerations because it meets all NDWAC minimum data requirements.

 This source is partially redundant, as it is mostly available as part of NCOD - Six Year
 (source 136).

 Data are retrievable by EPA but require special processing and analysis for CCL use.
 Designated as a supplemental source.

 Internet source not available (see source 136 National Drinking Water Occurrence Database
(NCOD) - 6-Year Data
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
 State of California EPA Chemicals Known to the State to Cause
 Cancer or Reproductive Toxicity

 191

 Proposition 65, the Safe Drinking Water and Toxic Enforcement Act of 1986, was enacted as
 a ballot initiative in November 1986. The Proposition was intended by its authors to protect
 California citizens and the State's drinking water sources from chemicals known to cause
 cancer, birth defects or other reproductive harm, and to inform citizens about exposures to
 such chemicals. Proposition 65 requires the Governor to  publish, at least annually, a list of
 chemicals known to the state to cause cancer or reproductive toxicity. (description from
 website)

 State of California

 Cynthia Oshita (916) 322-2068 California Office of Environmental Health Hazard
 Assessment coshita@oehha.ca.gov  Manager
 Susan Luong  (916) 327-3015 California Office of Environmental  Health  Hazard Assessment
  sluong@oehha.ca.gov Staff
Type of Data Elements
 Name, CASRN, Date added to list, Carcinogenicity and Reproductive Toxicity

                      A4-129

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EPA815-R-09-006
      August 2009
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source is considered relevant for the CCL Universe because it contains a list of
chemicals that is related to their toxicity/health effects.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.oehha.ca.gov/prop65/prop65 list/files/062802LSTa.pdf
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information


Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
State of New Jersey Hazardous Substances Right to Know Fact
Sheets

192

The New Jersey Worker and Community Right to Know Act, which became law in 1983,
requires public and private employers to provide information about hazardous substances at
their workplaces to:
- give public employees information about what hazardous substances are located at their
workplace and how to work with these hazardous substances safely;
- help firefighters, police and other emergency response personnel to adequately plan for
and respond to hazardous substance incidents such as fires, explosions or spills;
- provide data for monitoring and tracking  hazardous substances in the workplace and the
environment,  (description from website)

State of New Jersey

Program Manager: Richard Willinger
Phone: (609) 984-2202
e-mail: rtk@doh.state.nj.us

Field, Common Name, CAS RN, DOT Number, RTK Substance Number, Date, Revision,
Hazard Summary, Workplace Exposure Limits, Acute Health Effects, Chronic Health
Effects, Cancer Hazard, Reproductive Hazard, Other Long-term Effects

This source is considered relevant for the  CCL Universe because it contains information on
carcinogenicity and potential health effects.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://web.doh.state.ni.us/rtkhsfs/indexfs.aspx
Data Source Name
Identification Number
Data Source Description
Proprietor
STN - CA/CA Plus File - Chemical Abstracts

193

The CA File covers records from 1907 to the present from "international journals, patents,
technical reports, books, conference proceedings, and dissertations from all areas of
chemistry, biochemistry, chemical engineering, and related sciences." As of January 2004,
there are over 22 million records. The CA Plus File also includes all articles from over 1,600
chemical journals since October 1994.  (description from website)

Chemical Abstracts Service
Contact Information
Type of Data Elements
Chemical Abstracts Service
2540 Olentangy River Road
P.O. Box 3012
Columbus, OH 43210-0012

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or


                     A4-130

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EPA-OGWDW
         Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.cas.org/ONLINE/DBSS/cass.html
Data Source Name
Identification Number

Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
STN - CHEMLIST/HCHEMLIST - Regulated Chemical  Listing

194

CHEMLIST/HCHEMLIST contains lists of chemical substances in national and international
inventories, such as the TSCA Inventory, the European Inventory of Existing Commercial
Chemical Substances, the European List of Notified Chemical Substances, the Canadian
Domestic Substances and Non-Domestic Substances Lists, the Australian Inventory of
Chemical Substances, and others. The list also contains substances subject to regulation
under Title III of the Superfund Amendments and Reauthorization Act, the Resource
Conservation and Recovery Act (RCRA), and a total of 34 other U.S. regulatory lists. HPV
Chemical Lists from Australia and the United States are also included.  Over 227,000
records from 1979 to the present are included, (description from website)

Chemical Abstracts Service

Chemical Abstracts Service
2540 Olentangy River Road
P.O. Box 3012
Columbus, OH 43210-0012

Substance identity information, inventory status, source of information, and summaries of
regulatory activity, reports, and other compliance information

This source is considered relevant for the CCL Universe because it contains a list related to
health effects or occurrence.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet  retrievability criteria because it is only available through a
subscription.

http://www.cas.org/ONLINE/DBSS/dbsslist.html
Data Source Name
Identification Number

Data Source Description
Proprietor

Contact Information
Type of Data Elements



Relevance Explanation
STN - DETHERM

195

DETHERM contains over 500 chemical and physical properties for pure inorganic and organic
substances, compound classes, and homologous classes. Substance characteristics cover
thermodynamic, electric, transport, surface, and electrochemical properties, as well as
property relation and bibliographic information. The database consists of both factual


records (data tables) and citations. Sources include scientific journals, conferences,
handbooks, manufacturers' data, reports, standards, and file data. There are over 449,000
data tables and 53,000 bibliographic records in the database, (description from website)

Chemical Abstracts Service; Produced by DECHEMA e.V. and FIZ CHEMIE GmbH

Chemical Abstracts Service
2540 Olentangy River Road
P.O. Box 3012
Columbus, OH 43210-0012

Name, CASRN, Thermodynamic Properties, Multicomponent System Properties, Electric
Properties, Transport Properties, Surface Properties, Electrochemical Properties, Property
Relation Information, Data Type Information, State-of-System Information, Bibliographic
Information

This source does not meet relevance criteria because it contains only chemical property
                                                       A4-131

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         Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Completeness Explanation
Retrievability Explanation

Source URL
information that is not relevant to the CCL Universe.

It meets considerations because it meets all NDWAC minimum data requirements.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.cas.orq/ONLINE/DBSS/dethermss.html
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
STN - Handbook Of Data on Organic Compounds Database (HODOC)

196

HODOC is a numeric database that contains information from the nine-volume 2nd edition of
the Chemical Rubber Company (CRC) Handbook of Data on Organic Compounds.
According to the web site, "the HODOC File features the most frequently used physical and
chemical data of organic compounds and is an extensive source of spectral data."  Chemical
data include optical, physical property, and spectral data for a total of more than 25,000
organic substances, (description from website)

Chemical Abstracts Service

Chemical Abstracts Service
2540 Olentangy River Road
P.O. Box 3012
Columbus, OH 43210-0012

Name, CASRN, Chemical Data, Chemical Engineering, Chemistry, Engineering, Optical
Properties, Physical Properties, Property Data, Spectral Data, Crystal property description,
Density, MW, MP, formula, formula weight, refractive index, solubility, specific gravity

This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because it  is only available through a
subscription.

http://www.cas.ora/ONLINE/DBSS/hodocss.html
Data Source Name

Identification Number
Data Source Description
Proprietor

Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
STN - Merck Index Online (MRCK)

197

MRCK is the online version of the published Merck Index, 11th edition. It contains 10,415
records (as of April 2004) for chemicals, drugs, biologicals, and agricultural products.
Records include chemical, generic, and trade names; CAS numbers; molecular formulas;
therapeutic and commercial uses; structures; bibliographic citations to scientific literature;
and physical and toxicity properties from the late nineteenth century to the present.
Sources in the index include journals, books, patents, government reports, conference
proceedings, and file data,  (description from website)

Chemical Abstracts Service; Merck & Co., Inc.

Chemical Abstracts Service
2540 Olentangy River Road
P.O. Box 3012
Columbus, OH 43210-0012

Chemical  Name, Chemical  Name of Derivative, Company Name, Molecular Formula, Boiling
 Point, Pressure, Refractive Index of Parent Substance

This source does not meet  relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.
                                                       A4-132

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         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Retrievability Explanation

Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http://www.cas.orq/ONLINE/DBSS/mrckss.html
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements




Relevance Explanation

Completeness Explanation

Redundancy Explanation
STN - NUMERIGUIDE

198

NUMERIGUIDE contains "information on all of the numeric properties available in each
numeric database on STN, including appropriate terminology for each property, property
definition, files in which the property may be searched for, and default units for the property
 in each file." The file contains records on more than 875 types of numeric properties (as of
March 2002) and covers all of the STN numeric files, (description from website)

Chemical Abstracts Service; American Chemical Society (ACS)

Chemical Abstracts Service
2540 Olentangy River Road
P.O. Box 3012
Columbus,  OH 43210-0012

Name, Accession Number, Field Qualifiers, Notes, Preferred Property Name, Used For, All
fields containing hit terms, List of display fields containing hit terms, All Associated Terms,
Broader Terms, Definition, Description, STN File Name(s), Field, Qualifier(s), Display Field
Qualifier(s), Search Field Qualifier(s), Hierarchy Terms, Keyword Terms, Narrower Terms, All
 Preferred and Forbidden Terms, Used For Terms, Units, Use Terms

This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.

It does not  meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.
Retrievability Explanation

Source URL
This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.cas.ora/ONLINE/DBSS/numeriguidess.html
Data Source Name
Identification Number

Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation
STN - Toxicology Center (TOXCENTER)

199

TOXCENTER is a bibliographic database that draws on four other databases: BIOSIS, CA
Plus, I PA, and MEDLINE.  Relevant information includes literature from 1907 to the present
on carcinogenesis, chemically-induced diseases, environmental pollution, food
contamination, mutagenesis, teratogenesis, and toxicological analysis for drugs and other
chemicals such as agricultural pesticides.  Sources include books, bulletins, conference
proceedings, letters, journal articles, meetings, monographs, notes, papers, patents,
presentations, research and project summaries, reviews, technical reports,  and file data, for
a total of over six million records (as of April 2004). (description from website)

Chemical Abstracts Service

Chemical Abstracts Service
2540 Olentangy River Road
P.O. Box 3012
Columbus, OH 43210-0012

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
Completeness Explanation       It meets considerations because it meets all NDWAC minimum data requirements.
                                                        A4-133

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Redundancy Explanation
Retrievability Explanation

Source URL
This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.cas.ora/ONLINE/DBSS/toxcenterss.html
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
STN - ZREGISTRY

200

The ZREGISTRY File is a chemical structure and dictionary database containing unique
substance records for compounds identified by the CAS Registry System. The file contains
 records for all substances in the CAS Registry System, and provides the CAS registry
number and index name, synonyms, molecular formulas, nucleic acid and protein
sequences, ring analysis data, structure diagrams, and calculated physical properties for
over 12 million single-component organic substances.  This file also lists the ten most recent
 articles from the CA database citing the particular compound being searched for, and the
total number of CA citations for a substance, (description from website)

Chemical Abstracts Service

Chemical Abstracts Service
2540 Olentangy River Road
P.O. Box 3012
Columbus, OH 43210-0012

Name, CASRN, structure, STN files, HE data, MP, BP, BCF, Koc, LOGO, molar solubility,
MW, pKa; alloy composition tables, classes for polymers, nucleic acid and protein
Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
sequences, ring analysis data, and structure diagrams; other phys prop

This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.cas.ora/ONLINE/DBSS/zregistrvss.html
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
STN and STN Easy - Scientific and Technical  Information Network

201

STN provides a tool to search through over 200 scientific, technical, business, and patent
databases. Available data files cover a range of scientific fields, including many relevant to
drinking water contaminants (e.g., production, use, physicochemical properties,
environmental fate, and health effects). Twenty-four databases are directly relevant to
drinking water contaminant information gathering. In general, little  or no occurrence
information is available through the searchable databases, but a range of physicochemical
property and health effects data are available. Most of the 24 relevant databases are
bibliographic, with only a few numeric databases divided into specific records for different
chemicals. In addition, the few numeric databases that exist in STN are chemical property
databases, and do not include direct information on human health effects. STN Easy is a
web-only database searching tool, including 80 of the 200 STN databases, (description from
website)

Chemical Abstracts Service

Chemical Abstracts Service
2540 Olentangy River Road
P.O. Box 3012
Columbus, OH 43210-0012

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
                                                        A4-134

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EPA815-R-09-006
      August 2009
Relevance Explanation


Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.cas.org/stn.html
Data Source Name

Identification Number
Data Source Description
STORET - STORage and RETrieval

202

STORET is a water quality and biological and physical property data warehouse, containing
information from over 60 organizations in a new database from 1999, with access to pre-
1999 data starting from the 1960s. Organizations report on projects and other sampling
efforts, and this information is then made available to users, (description from website)
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Redundancy Explanation

Retrievability Explanation

Source URL
EPA

STORET User Assistance: 1-800-424-9067 or STORET@epa.gov

Estimated, Nitrogen, ammonia (NH3) as NH3 (mg/l), Estimated, Fecal Coliform (#/100ml),
Estimated Total Coliform (#/100ml)

This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.

This source is not redundant.

Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.

http://www.epa.gov/storet/
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Structure and Nomenclature Search System

271

Structure and Nomenclature Search System (SANSS) is designed to contain an entry for
each compound included in the other individual Chemical Information System (CIS)
databases. It also provides cross-reference referral capabilities to many other sources of
chemical information, enabling you to find additional data that may not be available online
through CIS.

SUBJECT COVERAGE:
CAS Registry Number
Chemical Abstracts Service name (8th or 9th Collective Index)
Synonyms and trade names
Molecular formula
Molecular weight
Structural diagram
(description from website)

National Information Services Corporation (NISC)

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Name, CASRN, Synonyms and trade names, Molecular formula, Molecular weight, Structural

                     A4-135

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EPA815-R-09-006
      August 2009
Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
 diagram

This source does not meet relevance criteria because it contains a chemical list that is not
related to health effects or occurrence.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http://www.nisc.com/cis/details/sanss.htm
Data Source Name
Substance Registry System (SRS)
Identification Number
Data Source Description
Proprietor
Contact Information

Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
203

The SRS is part of a single metadata registry, EDR, referencing EPA information resources.
 The system integrates several collections of EPA metadata, including data elements and
chemical identification information. SRS is EPA's central system for chemical and biological
 identification information, providing a common basis for identification of chemicals listed in
EPA regulations and data systems, as well as chemicals of interest from other sources. The
 database contains name and regulation information for over 83,000 substances from 95
information resources, (description from website)

EPA

Users can contact EPA using a form at the following location:
http://oaspub.epa.gov/srs/feedback$. startup

CAS RN, Classification, Molecular Formula, Molecular Weight, Regulatory Resources, Other
Sources, Group/Component, Related Links

This source is considered relevant for the CCL Universe because it contains a list of
chemicals that is related to potential exposure.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

SRS is retrievable by EPA. SRS is EPA's registry and provides the identifying EPA data
standards for the CCL substances.

http://iaspub.epa.gov/sor internet/reaistrv/substreg/home/overview/home.do
Data Source Name
Identification Number
Data Source Description
Proprietor

Contact Information
Type of Data Elements
Relevance Explanation
Superfund Contract Laboratory Program (SCLP) Water/Soil Data

181

Superfund CLP is a national network of EPA personnel, commercial laboratories, and
contractors that support EPA's Superfund effort by providing data of known and documented
quality. According to the web site, "since the inception of the CLP in 1980, more than 500
CLP laboratories have analyzed over 1,500,000 samples from more than 12,000 sites....over
1,850,000 soil and water samples for more than 150 chemicals from more than 10,000 sites
representing all ten EPA regions have been analyzed by over 430 laboratories." Data are
compiled in the CLP Analytical Results Database (CARD) and maintained by the Analytical
Operations Center,  (description from website)

EPA Headquarters Analytical Operations/Data Quality Center (AOC) in the Office of
Emergency and Remedial Response (OERR)

EPA Region 6 Main Office
1445 Ross Avenue
Suite 1200
Dallas, Texas 75202
(214)665-6444

Mean, Min, Max, Median, Measured/Estimated Concentrations

This source is considered relevant for the CCL Universe because it contains measurements

                     A4-136

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EPA815-R-09-006
      August 2009
Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
of contaminants in water, demonstrating occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
Data are retrievable by EPA but require special processing and analysis for CCL use.
Designated as a supplemental source.
http://www.epa.aov/earth1r6/6lab/hlclp.htm
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retriev ability Explanation
Source URL
Syracuse Research Corporation (SRC) - BIODEG
251
BIODEG contains experimental values as in CHEMFATE, but only relating to biodegradation
subjects. In addition, BIODEG contains evaluation codes that can be used for
structure/biodegradability correlations. This file contains over 5,800 records of actual
experimental results on biodegradation studies for approximately 800 chemicals.
Experimental details, such as chemical concentration and rate of degradation, are included.
(description from website)
Syracuse Research Corporation
301 Plainfield Road, Suite 350
Syracuse, NY 13212-2510
Phone:(315)452-8400
Fax:(315)452-8440
E-mail: escwebmaster@syrres.com
Name, CASRN, Biodegradation - aerobic, anaerobic, soil, sediment, sewage, fresh water,
seawater, other
This source is considered relevant for the CCL Universe because it contains information on
persistence, that may be used as an indicator of potential occurrence.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source meets retrievability criteria because it is in tabular format.
http://www.srcinc.com/what-we-do/prod uct.aspx?id=132
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Syracuse Research Corporation (SRC) - BIOLOG
254
BIOLOG, or the Microbial Degradation/Toxicity File, provides sources of microbial toxicity
and biodegradation data. It is is more detailed than DATALOG, but does not include
experimental values. BIOLOG contains 70,000 records on 8,150 chemicals,  (description
from website)
Syracuse Research Corporation/EPA
301 Plainfield Road, Suite 350
Syracuse, NY 13212-2510
Phone:(315)452-8400
Fax:(315)452-8440
E-mail: escwebmaster@syrres.com
Name, CAS RN, Formula, Biodeg-Tox, Oxygen Cond, Culture, Source, Mechanism, Data
Source
This source does not meet relevance criteria because it consists of text abstracts on
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
                     A4-137

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        Final CCL 3 Chemicals:
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EPA815-R-09-006
      August 2009
Source URL
automated retrieval.

http://www. srcinc.com/what-we-do/prod uct.aspx?id=132
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Syracuse Research Corporation (SRC) - CHEMFATE

252

CHEMFATE is a data value file containing 25 categories of environmental fate and
physical/chemical property information on commercially important chemical compounds.
Actual experimental values (rate constants, experimental conditions, physical properties,
etc.) are abstracted and retained in the file. CHEMFATE contains 17,260 records on 1,728
chemicals. Recently, recommended physical property values were collected for the SARA
Section 313 TRI chemicals, (description from website)

Syracuse Research Corporation

301 Plainfield Road, Suite 350
Syracuse, NY 13212-2510
Phone:(315)452-8400
Fax:(315)452-8440
E-mail: escwebmaster@syrres.com

Name, CASRN, MW, formula, MP, BP, UV absorption, pKa, log Kow, water solubility, VP,
HLC, evaporation from water, soil adsorption constant, soil column transport, soil think layer
chromotography, log bioconcentration factor, hydrolysis, oxidation and other reactions,
photolysis, microbial degradation, degradation in natural systems, ecosystem, air monitoring,
water monitoring, soil monitoring, biota monitoring, field studies

This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.srcinc.com/what-we-do/prod uct.aspx?id=132
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation
Syracuse Research Corporation (SRC) - Chemical Pointer File

184

The Chemical Pointer File contains pointers to important lists and inventories to each of the
25,000-plus chemicals in the file is listed. For instance, the pointers indicate if the chemical
is on EPA lists, on the TSCA inventory, in the NLM's database, in individual SRC EFDB
files, in the Pomona College MEDCHEM database, and  in the University of Arizona's
ARIZONA dATABASE of water solubility values, (description from website)

Syracuse Research Corporation

Dr. Philip Howard
Phone:(315)452-8417
301 Plainfield Road, Suite 350
Syracuse, NY 13212-2510
Main Phone: (315) 452-8400
Fax:(315)452-8440
E-mail: escwebmaster@syrres.com

Name, CASRN, structure, status on number of lists

This source does not meet relevance criteria because it  contains a chemical list that is not
related to health effects or occurrence.
Completeness Explanation      It meets considerations because it meets all NDWAC minimum data requirements.
Redundancy Explanation
This source is not redundant.
                                                       A4-138

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        Final CCL 3 Chemicals:
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EPA815-R-09-006
      August 2009
Retrievability Explanation

Source URL
This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.svrres.com/esc/chemical pointer.htm
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Syracuse Research Corporation (SRC) - DATALOG

253

DATALOG is a bibliographic file indexed by Chemical Abstract Service (CAS) registry
number that  contains eighteen types of environmental fate data. Since individual articles
require only cursory examination, no experimental values are entered into the file, and thus,
large numbers of chemicals can be rapidly incorporated. This file is the largest in the EFDB,
containing 380,000 records on over 16,800 chemicals. DATALOG indicates where
environmental fate and exposure data can be found by using the following 18 different
indexing terms:
Adsorption
Bioconcent ration
Biodegradation
Dissociation  constant
Ecosystems
Effluent concentrations
Evaporation  from water
Field studies
Food and crop concentrations
Henry's Law constant
Hydrolysis
Monitoring
Occupational concentrations
Octanol/water partition coefficent
Photooxidation
UV spectra
Vapor pressure
Water solubility
(description from website)

Syracuse Research Corporation/EPA

301 Plainfield Road, Suite 350
Syracuse, NY 13212-2510
Phone:(315)452-8400
Fax:(315)452-8440
E-mail: escwebmaster@syrres.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.srcinc.com/what-we-do/prod uct.aspx?id=132
Data Source Name
Syracuse Research Corporation (SRC) - Environmental Fate
Databases (EFDB)
Identification Number
Data Source Description
185

"EFDB is comprised of several interrelated files, DATALOG, CHEMFATE, BIOLOG, and
BIODEG.  These databases share a CAS registry number file containing over 20,000
chemicals with preferred name and formula, and a bibliographic file containing full references
on over 35,000 articles cited."
                                                       A4-139

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Proprietor

Contact Information




Type of Data Elements




Relevance Explanation

Completeness Explanation

Redundancy Explanation

Retrievability Explanation
BIODEG Description: BIODEG contains experimental values relating to biodegradation
studies.  BIODEG also includes information that may be used for "structure/biodegradability
correlations." The file contains records on a total of about 800 chemicals. This file may be
useful for identifying detailed biodegradation data.  MS Windows version fee is $100.00.;

BIOLOG Description: BIOLOG "provides sources of microbial toxicity and biodegradation
data.  It is more detailed than DATALOG but does not include experimental values."  The
database contains records for 8,000 chemicals. This database may be useful for examining
biodegradation of potential drinking water contaminants.  MS Windows version fee is
$100.00.;

CHEMFATE Description: CHEMFATE  "is a data value file containing 25 categories of
environmental fate and physical/chemical property information on commercially important
chemical compounds. Actual experimental values are abstracted and retained in the file."
This database contains data for a total of 1,728 chemicals, including physical property
values for Superfund Amendments and Reauthorization Act (SARA) Section 313 TRI
chemicals. This database may be useful for physicochemical properties for a wide range of
potential drinking water contaminants.  MS Windows version fee is $100.00.;

DATALOG Description: DATALOG is a bibliographic file containing 18 types of environmental
fate data such as bioconcentration, hydrolysis, and water solubility. The database is
indexed by CAS registry numbers, and contains data for over 16,500 chemicals.  Data are
not extracted from bibliographic references, and need to be retrieved manually for entry into
another database. This file may be useful for gathering environmental fate data, such as
water solubility, on a wide range of potential drinking water contaminants. MS Windows
version fee is $200.00. (description from website)

Syracuse Research Corporation; developed under the sponsorship of EPA, with support from
Dupont, Proctor & Gamble, and EPA for web version

301 Plainfield Road, Suite 350
Syracuse, NY 13212-2510
Phone:(315)452-8400
Fax:(315)452-8440
E-mail: escwebmaster@syrres.com

References relating to: Adsorption, Bioconcentration, Biodegradation, Dissociation constant,
Ecosystems, Effluent concentrations, Evaporation from water.Field studies, Food and crop
concentrations Henry's Law constant, Hydrolysis,  Monitoring, Occupational concentrations,
Octanol/water partition coefficent, Photooxidation, UV spectra, Vapor pressure, Water
solubility, Biodeg-Tox, Oxygen Cond., Culture, Source, Mechanism, Data Sources, CAS RN

This source is considered relevant for the CCL Universe because it contains information on
persistence, that may be  used as an indicator of potential occurrence.

It meets considerations because all of the sources it includes either meet all NDWAC
minimum data requirements or are peer reviewed.

This source is redundant.  It is available as a suite of data sources: BIOLOG, BIODEG,
CHEMFATE, and  DATALOG.

This source does not meet retrievability criteria because it is only available through a
subscription.
Data Source Name
Identification Number
Syracuse Research Corporation (SRC) - Physical Property Database
(PHYSPROP)
186
Data Source Description
The Physical Properties Database (PHYSPROP) contains chemical structures, names and
physical properties for over 25,250 chemicals. PHYSPROP has very limited data on
inorganic chemicals. The physical properties provided by PHYSPROP were gathered from a
variety of sources, and include experimental, extrapolated, and estimated values for melting
 point, boiling point, water solubility, octanol-water partition coefficient, vapor pressure, pKa,
Henry's law constant, and OH rate constant in the atmosphere.

PHYSPROP is available in  ISISBase format (MDL Information Systems, Inc.). This program
allows PHYSPROP to be searched by substructure, name fragment, or any of the physical
properties. PHYSPROP is  also available in SD File, MS-Excel97, and MS-Access formats.
                                                         A4-140

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EPA-OGWDW
        Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Proprietor

Contact Information


Type of Data Elements


Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
An on-line interactive demo version is also available which retrieves data for a subset of
some 25,000 chemicals from the PHYSPROP database. This free on-line database is
searchable by CAS Registry Number.  However the on-line demo only contains basic data
for chemicals and does not provide full reference citations or structure depictions. The on-
line demo does not have the sub-structure searching capabilities that are available with the
ISIS/Base (MDL Information Systems, Inc) version or Accord for Access (Synopsys
Scientific Systems, Ltd) version of PhysProp. (description from website)

Syracuse Research Corporation

Main Number (315) 452-8400 Fax Number (315)452-8440
Mailing Address 301 Plainfield Road, Suite 350 Syracuse, New York 13212-2510
escwebmaster@syrres.com

Name, CASRN,  MW, formula, structure, experimental, extrapolated, and estimated values
for melting point, boiling point, water solubility, octanol-water partition coefficient, vapor
pressure, pKa, Henry's law constant, and OH rate constant in the atmosphere

This source does not meet relevance criteria because it contains only chemical property
information that  is not relevant to the CCL Universe.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.svrres.com/esc/phvsprop.htm
Data Source Name


Identification Number
Data Source Description
Proprietor

Contact Information
Type of Data Elements
Relevance Explanation
Syracuse Research Corporation (SRC) - Simplified Molecular Input
Entry System (SMILECAS Database)

187

SMI LECAS contains SMILES notations for molecular structures of over 103,000 compounds
used in developing structure-activity relationships.

Available for free download at:
http://www.epa.gov/oppt/exposure/docs/episuitedl.htm
(description from website)

Syracuse Research Corporation/EPA

Mailing Address:
301 Plainfield Road, Suite 350
Syracuse, New York 13212-2510
escwebmaster@syrres.com
Main Number (315) 452-8400
Fax Number (315)452-8440

CAS RN, Chemical Name, SMILES notation

This source does not meet relevance criteria because it contains only chemical property
information that  is not relevant to the CCL Universe.
Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
It meets considerations because it meets all NDWAC minimum data requirements.

This source is redundant with NCI-3D (source 135).

This source meets retrievability criteria because it is in tabular format.

http://www.svrres.com/esc/smilecas.htm
Data Source Name

Identification Number
Data Source Description
Terrestrial Toxicity Information

282

The TERRETOX database contains records related to the toxic effects of chemical

                     A4-141

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        Identifying the Universe
EPA815-R-09-006
      August 2009
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
substances on terrestrial animals. It deals primarily with mammals and birds, although some
insects, amphibians and other species are included.

SUBJECT COVERAGE:
Assay Results/Analysis
CAS Registry Numbers
Chemical Name Identification
Environmental Effects
 Species Identification
Test Conditions
Toxicology
(description from website)

National Information Services Corporation (NISC)/EPA

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is redundant with ECOTOX (source 57).

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.nisc.com/cis/details/terretox.htm
Data Source Name
Identification Number
Data Source Description
The Institute for Genomics Research (TIGR) Microbial Database

207

The Institute for Genomics Research (TIGR) microbial database catalogs over 60 published
microbial genomes and genomes in progress. Some notable enteric microbes' genomes
have been published, including Campylobacterjejuni, E. Coli O157: H7, Helicobacter pylori,
Pseudomonas aeruginosa, Salmonella typhi and typhimurium, and Vibrio cholerae.
(description from website)
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
The Institute for Genomics Research (TIGR)

tdb@tigr.org

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.tiar.ora/tdb/mdb/mdbcomplete.html
                                                       A4-142

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EPA-OGWDW
         Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information

Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
The Manual of Clinical  Microbiology, 7th edition.
205
The Manual is a reference for clinical microbiologists, pathologists, clinicians, and students.
Coverage includes general issues in clinical microbiology, the clinical microbiology lab in
infection control and prevention, diagnostic technologies in clinical microbiology,
bacteriology, virology, mycology, parasitology, antimicrobial agents and susceptibility
testing, and reagents, stains, and media. This edition is enhanced by perspectives from
editors and authors outside the US. Some material is consolidated and reorganized.
(description from website)
American Society for Microbiology
Ordering information available: http://www.amazon.com/exec/obidos/tg/detail/-
/1555811264/102-1971644-1055309?v=glance
Data elements for microbial contaminants
This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.
http://www.amazon.eom/exec/obidos/tg/detail/-/1555811264/102-1971644-1055309?v=glance
Data Source Name
Identification Number
Data Source Description

Proprietor
Contact Information
The National Environmental Methods Index (NEMI)
138
NEMI is a web-based index of analytical methods.  The purpose of NEMI is to provide a
unified, easy-to-access source for methods.  This database focuses on methods appropriate
for detection in ambient water, (description from website)
USGS
Although there is not an official help desk for NEMI, help regarding technical problems with
the use of this site is available within the United States at 608-821-3869 during regular
business hours Monday through Friday.
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.
It meets considerations because it is peer reviewed.
This source is not redundant.
This source does not meet retrievability criteria. This source has data in a tabular format,
but it is not formatted to allow complete data extraction with automated retrieval.
http://www.nemi.gov
Data Source Name

Identification Number
Data Source Description

Proprietor
The Office of Ground Water and Drinking Water (OGWDW)
Consumer Fact Sheets
153
These fact sheets comprise a text-based summary of information on health effects,
releases to water, and occurrence for over 90 regulated drinking water contaminants.
(description from website)
EPA Office of Ground Water and Drinking Water
                                                       A4-143

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EPA-OGWDW
        Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Contact Information

Type of Data Elements




Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Safe Drinking Water Hotline - 800-426-4791
hotline-sdwa@epa.gov

What is CHEMICAL, and how is it used?, Why is CHEMICAL being regulated?, What are the
Health Effects?, How much CHEMICAL is produced and released?, What happens to
CHEMICAL when it is released?, How will Chemical be Detected in and Removed from My
Drinking Water?, How will I know if Chemical is in my drinking water?, Drinking Water
Standards (MCLG, MCL), Releases to Water and Land

This source does not meet relevance criteria because it contains only information for
regulated contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.epa.gov/safewater/hfacts.html
Data Source Name


Identification Number
Data Source Description


Proprietor
Contact Information
The Office of Ground Water and Drinking Water (OGWDW) -
Technical Fact Sheets

154

Technical fact sheets are published on the web by OGWDW, and include chemical and
physical properties, trade names for the chemical, and other regulatory information.
(description from website)

EPA Office of Ground Water and Drinking Water

Safe Drinking Water Hotline - 800-426-4791
hotline-sdwa@epa.gov
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
This source does not meet relevance criteria because it contains only information for
regulated contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.epa.gov/safewater/hfacts.html
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
The Open Practical Knowledge Acquisition Toolkit (TOPKAT)

240

TOPKAT is a commercial computational toxicology package that uses chemical structural
information (2-D descriptors of structural fragments) and QSAR models to estimate a range
of human health toxicological and non-human ecological endpoints. Predictions are made for
 untested chemicals by comparison with structural fragments contained in the model's
training set. It is one of a number of toxicological QSAR packages available, as reviewed
previously in "Status and Feasibility of Using (Quantitative) Structure-Activity Relationships
((Q)SAR) for CCL Development" July, 2003. (description from website)

Accel rys

Accel rys
9685 Scranton Road
San Diego
CA92121
Phone: (800) 756-4674
Phone: (858) 799-5509
Fax:(858)799-5102
E-mail: support-us@accelrys.com
                                                      A4-144

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EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Type of Data Elements
Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
SMILES, Compund Name, Primary ID, Secondary ID, Rodent Carcinogenicity, Ames
Mutagenicity, Rat Oral LD50, Rat Chronic LOAEL, Developmental Toxicity Potential, Skin
Sensitization, Fathead Minnow LC50, Daphnia Magna EC50, Weight of Evidence Rodent
Carcinogenicity, Rat Maximum Tolerated Dose, Aerobic Biodegradability, Eye Irritancy, Log
P, Rabbit Skin Irritancy, Rat Inhalation Toxicity LC50, Rat Maximum Tolerated Dose

This source is considered relevant for the CCL Universe  because it could be a source of
information on potential health effects.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria. The source does not contain data;  it is a
model that might be used to generate estimates.  The source is only available through a

http://www.accelrvs.com/products/topkat/
Data Source Name


Identification Number

Data Source Description
The Prokaryotes: A handbook on the biology of bacteria:
Ecophysiology,  Isolation, Identification, and Applications

206

The Prokaryotes provides information on prokaryotic ecophysiology and biochemistry,
prokaryotoc organisms, symbiotic associations, and biotechnology.
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Balows, A et al. (ed.), Springer-Verlag, New York (4 volumes)

springerlink@springer-ny.com

Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http://141.150.157.117:8080/prokPUB/index.htm
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information


Type of Data Elements
Relevance Explanation

Completeness Explanation
The Toxics Release Inventory (TRI)

212

TRI contains information from almost 23,000 U.S. companies and government facilities that
report their air, land, and water releases of industrial chemicals and other waste management
activities. TRI also contains some information about source reduction efforts. This
database's information on releases to water are a valuable source of potential occurrence
data for screening drinking water contaminants. It includes many categories of air, land, and
water release data for the years 1988 through 2001. As of April, 2004, "the TRI toxic
chemical list contains 582 individually listed chemicals and 30 chemical categories (including
three delimited categories containing 58 chemicals).  If the members of the three delimited
categories are counted as separate chemicals then the total number of chemicals and
chemical categories is 667 (i.e., 582 + 27 + 58)." (description from website)

EPA

TRI Program Division
Phone: 202-566-0250
Email: tri.us@epa.gov

Chemical releases to air, land, and water

This source is considered  relevant for the CCL Universe because it contains information on
chemical releases, which may indicate potential occurrence.

It meets considerations because it is  peer reviewed.
                     A4-145

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Redundancy Explanation
Retrievability Explanation

Source URL
This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.epa.gov/triexplorer/
Data Source Name

Identification Number
Data Source Description
TOMES PLUS, MICROMEDEX - Thomson-Micromedex

208

The TOMES Plus® System offers access to medical, environmental, and hazard information
needed for safe management of chemicals. Its vast array of references includes licensed
as well as proprietary databases available only from MICROMEDEX. The System's unique
Integrated Index® feature saves valuable time by searching all databases simultaneously
using more than 2.1 million synonyms. All data are prepared and reviewed by experts in the
fields of environmental, industrial, and reproductive toxicology; occupational medicine; and
industrial hygiene and safety, (description from website)
Proprietor
Contact Information


Type of Data Elements


Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Thomson Micromedex

Phone: (800) 525-9083, press option 4,2
Fax: (800) 635-6339
Email: mdx.custsvc@thomson.com

Identification & Synonyms, Range of Toxicity, Toxicity/Biomedical Effects, Environmental
Fate/Exposure Potential, Chronic Health Hazard Assessments for Non-Carcinogenic Effects,
 Carcinogenicity Assessments for Lifetime Exposure

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval, and it is only available through a subscription.

http://www.micromedex.com
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Total Exposure Assessment Methodology Study (TEAM)

250

The Total Exposure Assessment Methodology (TEAM) study was designed to develop
methods to measure individual total exposure (exposure through air, food, and water) and
resulting body burden of toxic and carcinogenic chemicals, and to apply these methods
within a probability-based sampling framework to estimate the exposures and body burdens
of urban populations in several U.S. cities.  The TEAM Study reports the results of eight
monitoring studies performed in five communities during different seasons of the year.
Breath, personal, outdoor, and water samples were collected for volatile organic compounds.
 Results of the TEAM Study are reported in a four volume report entitled: The Total
Exposure Assessment Methodology (TEAM) Study. Two of the four volumes provide data in
 a form that can be incorporated into Version 2 of the Endocrine Disrupter Priority-Setting
Database (EDPSD v.2).  These volumes are: (1) The Total Exposure Assessment
Methodology (TEAM) Study: Elizabeth and Bayonne, New Jersey, Devils Lake, North
Dakota, and Greensboro, North Carolina: Volume II. Part 2 and (2) The Total Exposure
Assessment Methodology (TEAM) Study: Selected  Communities in Northern and Southern
California: Volume III. Altogether the TEAM Study provides data on 30 volatile organic
compounds from breath, personal air, outdoor air, and water samples. Table 1 lists the
compounds and provides information on the media for which data is reported for them.

U.S. Environmental Protection Agency, Office of Acid Deposition, Environmental Monitoring
and Quality Assurance. Project Summary: The Total Exposure Assessment  Methodology
(TEAM) Study. EPA-600-S6-87-002, 1987. (description from ERG)

EPA

EPA/Eastern Research Group

                     A4-146

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Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation
703-633-1600

Name, CAS RN, Central tendency, Units, Method of Measurement, Number of samples,
Percent of the samples that were measurable, Population, Water Type, Location, Season

This source is considered relevant for the CCL Universe because it contains information on
potential health effects.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated  retrieval.
Source URL
N/A
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information

Type of Data Elements
Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Toxic Substances Control Act (TSCA) List

288

The Toxic Substances Control Act (TSCA) of 1976 requires the Environmental Protection
Agency (EPA) to maintain a list of chemical substances that have been manufactured,
imported, or processed in the United States for commercial purposes since January 1, 1975.
The TSCA contains this list and is commonly referred to as the TSCA Inventory. Note that
the database contains only the public portion of the Inventory; a supplemental, "confidential"
portion of the Inventory is maintained by EPA.

EPA
Unknown

This source is considered relevant for the CCL Universe because it is a list and contains
information on production volume, which may indicate potential occurrence.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source meets retrievability criteria because it is accessible through EPA's Substance
Registry System.

http://www.epa.qov/oppt/index.htm
Data Source Name
Health


Identification Number
Data Source Description
Proprietor
Contact Information
Toxicity Criteria Database - California Office of Environmental


Hazard Assessment (OEHHA)

209

The Toxicity Criteria Database contains information on over 260 chemicals. The database
reports information that includes the following: cancer potency information (oral/inhalation
slope factors), chronic and acute Reference Exposure  Levels (RELs), California Public
Health Goals (CPHG), California Proposition 65 No Significant Risk Levels (NSRLs), and
Maximum Allowable Daily Levels (MADLs).

The Technical Support Document for Describing Available Cancer Potency Factors (TSD)
contains cancer unit risks and potency factors for 121 of the 201 carcinogenic substances
or groups of substances for which emissions must be quantified in the Air Toxics Hot Spots
program. The purpose of this document is to provide a summary of the data supporting the
carcinogenic potential of the substance or group of substances and to provide the calculation
 procedure used to derive the estimated unit risk and cancer potency factors. For the
complete document, goto http://www.oehha.ca.gov/air/cancer_guide/TSD2.html to download.
 (Description from website)

California Office of Environmental Health Hazard Assessment

Office of Environmental Health Hazard Assessment

                     A4-147

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Type of Data Elements
California Environmental Protection Agency
1515 Clay Street, 16th Floor
Oakland,  California 94612
(510)622-3200

Critical effect, CAMCL, CAPHG, cancer risk, cancer groups, MADL, NSRL, REL, slope
factor, unit risk
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
This source is considered relevant for the CCL Universe because it contains data elements
derived from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.oehha.ca.gov/risk/ChemicalDB/index.asp
Data Source Name

Identification Number
Data Source Description
Proprietor

Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation
TOXLINE

211

TOXLINE is the National Library of Medicine's extensive collection of online bibliographic
information covering the biochemical, pharmacological, physiological, and toxicological
effects of drugs and other chemicals. It contains more than 3 million bibliographic citations,
almost all with abstracts and/or indexing terms and CAS Registry Numbers. TOXLINE
references are drawn from various sources grouped into two major parts-TOXLINE Core and
TOXLINE Special - both of which operate under versatile search engines offering a variety of
 search and  display capabilities.

Components of Toxline Special:
Special journal and other research literature: Developmental and Reproductive Toxicology
(DART®®),  International Labour Office (CIS), Swedish National Chemicals Inspectorate
(RISKLINE)
Technical reports and research projects: Federal Research in Progress (FEDRIP), Toxic
Substances  Control Act Test Submissions (TSCATS), Toxicology Document and Data
Depository (NTIS), Toxicology Research Projects (CRISP)
Archival collection (no longer being updated): Aneuploidy (ANEUPL), Environmental Mutagen
Information Center File (EMIC), Environmental Teratology Information Center File (ETIC),
Epidemiology Information System (EPIDEM), Hazardous Materials Technical Center (HMTC),
 Health Aspects of Pesticides Abstract Bulletin (HAPAB), International Pharmaceutical
Abstracts (IPA), NIOSHTIC (NIOSH), Pesticides Abstracts (PESTAB), Poisonous Plants
Bibliography (PPBIB), Toxicological Aspects of Environmental Health (BIOSIS)
(description  from website)

National Library of Medicine; created by NLM, maintained by the Toxicology and
Environmental Health Information Program (TEHIP)

Specialized  Information Services
National Library of Medicine
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Telephone: (301) 496-1131
FAX (301) 480-3537
e-mail: tehip@teh.nlm.nih.gov
URL: http://sis.nlm.nih.gov

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source  does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.

This source  is not redundant.

This source  does not meet retrievability criteria because the data are not formatted for
automated retrieval.
                                                         A4-148

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Source URL
http://toxnet.nlm. nih.aov/cai-bin/sis/htmlgen?TOXLINE
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
TSCA Plant and Production

284

The U.S. Toxic Substances Control Act (TSCA) required the establishment of an inventory of
the many chemicals found in U.S. commerce during the period 1975 through 1977. This
inventory was generated by the manufacturers and importers of chemical substances in
commercial quantities. Processors and users also reported chemicals that they used.

SUBJECT COVERAGE:
Chemical Name Identification
CAS Registry Number
Manufacturer Address Information
Production Volume
Plant Site Information
(description from website)

National Information Services Corporation (NISC)

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Name, CASRN, Manufacturer Address Information, Production Volume, Plant Site Information

This source is considered relevant for the CCL Universe because it is a list and contains
information on production volume, which may indicate potential occurrence.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.nisc.com/cis/details/tscapp.htm
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
TSCATS - Toxic Substances Control Act Test Submissions

213

TSCATS "is a central system for the collection, maintenance, and dissemination of
information on unpublished technical reports submitted by industry to EPA under TSCA.
Studies on over 8,000 chemicals are categorized into three broad subject areas (i.e., health
effects, environmental effects, and environmental fate)." TSCATS draws on 81,000 studies
on 8,000 chemical substances. The database includes data on chemical exposure studies,
epidemiology, environmental fate, monitoring, and episodic incidents, such as spills and
case reports,  (description from website)

Syracuse Research Corporation; Developed and maintained by SRC for EPA

301 Plainfield Road, Suite 350
Syracuse, NY 13212-2510
Phone:(315)452-8400
Fax:(315)452-8440
E-mail: escwebmaster@syrres.com

CAS RN, Name, Study Purpose, Organism, Rte Admin, Test, Ref
Relevance Explanation
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.
                     A4-149

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Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http ://www. epa. gov/oppt/tscaSe/i ndex. htm
Data Source Name
Identification Number

Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation
Source URL
UCM  - Round 2 (SDWIS/FED) - Unregulated Contaminant Monitoring

214

UCM-Round 2 contains actual monitoring results (i.e., parametric data) from drinking water
PWSs used to support occurrence analyses for various OGWDW projects (from 1992-1997).
 The Safe Drinking Water Information System/Federal Version (SDWIS/FED) generally
covered the Round 2 unregulated contaminant monitoring period.  These data were originally
submitted by the States drinking water agencies to EPA and stored in SDWIS/FED. The
Cadmus Group, Inc., currently maintains the extensively edited, working version here
referred to as UCM-Round 2 (SDWIS/FED). The database covers 48 contaminants,
including unregulated lOCs, unregulated SOCs, and mandatory and discretionary VOCs for
33,800  PWSs. A detailed description of this data source can be found in Occurrence of
Unregulated Contaminants in Public Water Systems: An Initial Assessment (EPA, 2001; EPA
815-P-00-001).

The Cadmus Group,  Inc.; EPA OGWDW

Erin Mateo
The Cadmus Group
57 Water Street
Watertown, MA 02472
T: 617-673-7000
F: 617-673-7001

Drinking Water Occurrence Concentrations

This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.

It meets considerations because it is peer reviewed.

This source is redundant, as it is wholly available as part of NCOD - Round 1&2 (source 137).

This source meets retrievability criteria because it is in tabular format.

Error! Hyperlink reference not valid.
Data Source Name

Identification Number
Data Source Description
University of Akron Chemical Database

216

This database allows the user to retreive information for any of 23,495 hazardous chemicals
or 'generic' entries based on a keyword search. Potential keywords include names, formula
and registry numbers (CAS, DOT, RTECS, EINECS, Beilstein, Merck and EPA). Formula are
represented in Hill format for searching and a more descriptive format for viewing.

This data base and the information it contains were independently compiled by the author
from a large number of sources, and the data included as well as the manner in which it is
presented have been independently chosen by the author to provide what is deemed to be
an academic publication. Among the published references available, particular mention
should be made of:
                                  2000 Emergency Response Guidebook ERG2000, 2000
                                  Hazardous Chemicals Data NFPA49, PC-49-94, 1994
                                  Canadian WHMIS - Workplace Hazardous Materials Information System
                                  U.S.C.G CHRIS database
                                  U.S. EPA Cameo database
                                  NIOSH/OSHA exposure limit data
                                  Manufacuturer/supplier MSDS sheets

                                                       A4-150

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Proprietor

Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Various governmental registry lists
(description from website)

University of Akron

jkh@chemistry.uakron.edu

Formula, Structure, Description, Uses, CAS, Partition coefficient, Solubility in water, Melting
point, UN number, Hazard class, Packing Group

This source does not meet relevance criteria because it contains only chemical property
information that is not relevant to the CCL Universe.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not  redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://ull.chemistrv.uakron.edu/erd/index.html
Data Source Name


Identification Number

Data Source Description
Proprietor

Contact Information

Type of Data Elements

Relevance Explanation
University of Maryland - Partial List of Acute Toxins/Partial List of
Teratogens

217

Has been combined with the University of Maryland - Partial List of Teratogens (Source
218).

The Partial List of Acute Toxins is an alphabetical compilation of chemical substances that
met the University of Maryland definition of an "Acute Toxin" for the purpose of the
University of Maryland Chemical Hygiene Plan.

Acute toxins are defined as substances that have a median lethal dose (LD50) less than or
equal to 50 mg/kg body weight by the oral route of entry; 200 mg/kg body weight by the
dermal route of entry or a median lethal concentration (LC50) less than or equal to 0.5 mg/l
where time of exposure is eight hours or less. This definition is compatible with the 1994
Department of Transportation definition of "Poison."

This list is intended for use by University of Maryland laboratory personnel as an aid in
determining substances for which "designated use areas" will be required under the
University of Maryland Chemical Hygiene Plan.  It is important to remember that this list is
not comprehensive. It does not include all acute toxins and does not list teratogens,
mutagens or select carcinogens. Additional lists may be accessed from the same INFORM
menu for other chemical hazard classifications to assist chemical hazard identification.
(description from website)

University of Maryland

University of Maryland Department of Environmental Safety (DES) Industrial Hygiene
division (301) 405-3960

Name

This source is considered relevant for the CCL Universe because it contains a list of
chemicals with known toxicity/health effects.
Completeness Explanation
Redundancy Explanation
Retrievability Explanation
Source URL
It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

https://des.umd.edu/chemlists/acute.cfm
Data Source Name
University of Minnesota Biocatalysis & Biodegradation Database
(UM-BBD)
                                                       A4-151

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Identification Number
Data Source Description
Proprietor

Contact Information

Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
215

UM-BBD contains information on microbial biocatalytic reactions and biodegradation
pathways for primarily xenobiotic chemical compounds. The database contains lists of 861
compounds, 915 reactions, 140 pathways, 583 enzymes, 332 microorganisms, and 50
organic functional groups, (description from website)

Maintained by the University of Minnesota, with support from the International Scientific
Advisory Board

Users can contact UM-BBD using the form at the following location:
http://umbbd.ahc.umn.edu/contact.html

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.labmed.umn.edu/umbbd/index.html
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Unregulated Contaminant Information System (URCIS)

219

URCIS contains actual monitoring results (i.e., parametric data) from drinking water PWSs
used to support occurrence analyses for various OGWDW projects. URCIS generally
covered the Round 1 unregulated contaminant monitoring period (1983-1992).  Extensive
data "clean-up" was necessary to resolve data quality issues within the various data sets.
These data quality issues, as well as the current status of the data sets, are described in
Occurrence of Unregulated Contaminants in Public Water Systems: An Initial Assessment
(EPA,  2001; EPA 815-P-00-001).

The Cadmus Group, Inc.; EPA OGWDW

Erin Mateo
The Cadmus Group
57 Water Street
Watertown, MA 02472
T: 617-673-7000
F: 617-673-7001

Drinking Water Occurrence Concentrations
Relevance Explanation

Completeness Explanation

Redundancy Explanation

Retrievability Explanation

Source URL
This source is considered relevant for the CCL Universe because it contains measurements
of contaminants in water, demonstrating occurrence.

It meets considerations because it is peer reviewed.

This source is redundant, as it was converted into NCOD Round 1 database, so URCIS is no
 longer needed.

This source meets retrievability criteria because it is in tabular format.

Error! Hyperlink reference not valid.
Data Source Name


Identification Number

Data Source Description
US Army Center for Health Promotion and  Medicine Detailed
Chemical Fact Sheets

220

Chemical fact sheets containing information on the physical properties and toxic properties

                     A4-152

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Proprietor
Contact Information

Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
of weaponry agents.

U.S. Army Center for Health Promotion and Medicine

Users can request information using the form at the following website: http://chppm-
www.apgea.army.mil/contactusAA/email.asp

Chemical Formula, Description, Overexposure Effects, Reactivity Data, Toxicity Values,
Exposure Limits

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://chppm-www.apaea.armv.mil/dts/dtchemfs.htm
Data Source Name
Identification Number
Data Source Description
US  EPA Civil Enforcement Docket
273
The DOCKET database contains information on all civil judicial cases filed by the
Department of Justice on behalf of the US Environmental Protection Agency and is the
official EPA database for tracking and reporting information on civil judicial and
administrative enforcement cases under all environmental statutes. The database is
maintained by EPA within the Office of Enforcement and Compliance Assurance (OECA).
Data entry is performed in each  EPA Region and Headquarters.  Records can be retrieved
for a site by using the facility or company name, address, EPA ID number, case
information, or dates.

Users can search by chemical or other name, chemical name fragment, Chemical Abstracts
Service Registry Number (RN), and/or subject terms. Search results can easily be viewed,
emailed, printed or downloaded.

Information Available:
Information tracked in DOCKET  covers four broad areas:
1) Basic civil judicial and administrative enforcement case information: Law(s) and section(s)
violated,  Facility information, Defendants/PRPs/Respondents, Penalty/cost recovery data,
Case attorney(s)/Technical contacts;
2) Descriptive text information: Case summary that provides a description of the case,
Status comments that describe case progress; 3) Case development milestones: Case
dates to track progression as the case moves form the Region, to DOJ, to court, then to
 EPA Identification Number
Proprietor
Type of Data Elements


Relevance Explanation
conclusion; 4) Case conclusion information: Final disposition of case,
Penalty and cost recovery data, Compliance with consent instrument, Supplemental
environmental projects,
Injunctive relief, Environmental justice data

SUBJECT COVERAGE:
Facility Location Data
Court Docket Number

File and Conclusion Dates
Case Names
 Disposition
Violation Laws,  Sections, and Types
Penalties and Recoveries
Pollutants
Defendant Information
(description from website)

National  Information Services Corporation (NISC)

Case Number, Violated Law & Section, Violation Type, Date Filed, Date Concluded, Docket
Number, Assessed Fedral Penalty, Disposition of Case, Defendants, EPAID, Facility Name,
 Street, City, State.ZIP

This source does not meet relevance criteria because it consists of text abstracts on

                      A4-153

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Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
subjects not pertaining to CCL CP, and its data elements are inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.nisc.com/cis/details/DOCKET.HTM
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation
Victorian Infectious Diseases Reference Laboratory (VIDRL)

221

The Victorian Infectious Diseases Reference Laboratory (VIDRL) is a Victorian public health
reference laboratory with core responsibilities in virology and mycobacteriology. VIDRL also
provides expertise in bacteriology, parasitology, epidemiology and molecular detection
technologies, (description from website)

Victorian Infectious Diseases Reference Laboratory (Australia)

Victorian Infectious Diseases Reference Laboratory
lOWreckyn St, North Melbourne
Victoria, Australia, 3051
Phone: (613)93422600
Facsimile: (613) 9342 2666 or (613) 9342 2660

Bibliographic information,  indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
inconsistently presented.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.vidrl.org.au/contact/contact.htm
Data Source Name
Identification Number
Data Source Description
Proprietor

Contact Information
Type of Data Elements
Voluntary Cosmetic Registration Program Database (VCRP)
The Voluntary Cosmetic Registration Program (VCRP) is a voluntary data collection effort
initiated by the FDA that maintains information on cosmetic ingredients and reports of
cosmetic-related injuries.  Since the FDA lacks authority to require manufacturers to register
their cosmetic establishments, only companies that wish to participate in the program
forward data to the FDA.  Registered manufacturers or distributors are notified by the FDA if
a cosmetic ingredient may be harmful, (description from website)

FDA - Center for Food Safety and Applied Nutrition; Program maintained by FDA's Office of
Cosmetics and Colors; established at the request of cosmetic industry

Mary V. Waleski
Chief, Cosmetics Programs & Regulation Branch
HFS-106
Food and  Drug Administration
5100 Paint Branch Parkway
College Park, MD 20740-3835
Phone: (202)418-3414
Fax: (202) 208-6937

Bibliographic information,  indexing terms, abstracts, chemical names, and CAS Registry
Numbers
                                                       A4-154

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        Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Relevance Explanation


Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://vm.cfsan.fda.aov/~dms/cos-regn.html
Data Source Name
Identification Number
Data Source Description
Wastelnfo - AEA Technology

223

Wastelnfo is a comprehensive collection of references to international literature on non-
nuclear waste management and associated issues. The file covers the technical, policy, and
economic aspects of the subject, as well as all aspects of the waste management hierarchy:
 minimization, recovery, recycling, treatment and disposal.

References are selected from journals, conferences, books, reports, legislative documents,
theses and patents. Because waste management is a multidisciplinary subject, a wide array
of journals from a variety of fields are covered, as well as the literature from the waste
management and environmental fields, (description from website)
Proprietor
Contact Information
Type of Data Elements
AEA Technology

Manager, Waste Management Information Bureau
AEA Technology Environment
F6Culham,OX143ED
United Kingdom
Telephone: +44 1235 463162
Fax:+44 1235 463004
E-Mail: wmib@aeat.co.uk

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers
Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://librarv.dialog.com/bluesheets/html/bl0110.html
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Water Environment Research Foundation (WERF) Microsheets

228

WERF Microsheets is a valuable database on waterborne microorganisms and emerging
pathogens and is available to WERF subscribers through a cooperative agreement with UK
Water Industry Research. The database provides information on occurrence, detection,
treatment, and other facts about microorganisms, (description from website)

UK Water Industry Research & Wrc-NSF Ltd.

WERF
635 Slaters Lane, Suite 300
Alexandria VA 22314
Telephone: (703) 684-2470
Fax: (703) 299-0742
Email: werf@werf.org
                                                       A4-155

-------
EPA-OGWDW
         Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
Data elements for microbial contaminants

This source does not meet relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.werf.Org//AM/Tem plate. cfm?Section=Home
Data Source Name
Water Environment Research Foundation (WERF) Toxicity
Datasheets
Identification Number

Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
229

WERF Datasheets is a valuable database on contaminant substances and is available to
WERF subscribers through a cooperative agreement with UK Water Industry Research. The
database provides information on occurrence, detection, treatment, and other facts about
contaminant substances, (description from website)

UK Water Industry Research & Wrc-NSF Ltd.

WERF
635 Slaters Lane, Suite 300
Alexandria VA 22314
Telephone: (703) 684-2470
Fax: (703) 299-0742
Email: werf@werf.org

Unknown

This source is considered relevant for the CCL Universe because it could be a source of
information on health effects.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because it is only available through a
subscription.

http://www.werf.Org//AM/Tem plate. cfm?Section=Home
Data Source Name

Identification Number
Data Source Description
Water Resources Abstracts - Cambridge Scientific Abstracts

224

Water Resources Abstracts provide summaries of the world's technical and scientific
literature on water-related topics covering the characteristics, conservation, control, pollution,
treatment, use and management of water resources. Abstracts are drawn from journals,
books, conference proceedings, and technical reports in the physical and life sciences, as
well as from engineering, legal and government publications.

Until 1994, the database was produced by the United States Geological Survey, when it was
generally known as Selected Water Resources Abstracts. Since that time, Water Resources
Abstracts has been produced by Cambridge Scientific Abstracts, which broadened the scope
by including more material published outside the U.S. This database, which concentrates on
water supply and water treatment, complements the Aquatic Sciences & Fisheries Abstracts
database, ASFA, where there is greater coverage of the marine environment and  biological
material.

Subscribers to Water Resources Abstracts on the Internet Database Service have free
access to Water Resources Netsites. This is a special service providing links to other
bibliographic databases, research and development programs, data sets, lists of experts and

                     A4-156

-------
EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Proprietor
Contact Information
 researchers, conference and meetings information, and other resources on the Internet.
These sites have been carefully selected and evaluated by Cambridge Scientific Abstracts
editors who are all subject experts in their field, (description from website)

Cambridge Scientific Abstracts

Cambridge Scientific Abstracts
7200 Wisconsin Avenue
Bethesda, MD 20814 USA
Voice: 800-843-7751 (in N. America)
Voice: +1 301-961-6700 (worldwide)
Fax:+1 301-961-6720
Email: sales@csa.com
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.csa.com/csa/ids/databases-collections.shtml -environmental
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
Water Resources Worldwide

225

Water Resources Worldwide provides four of the world's major water-resource databases
plus powerful searching using the WATERLIT thesaurus. South Africa's WATERLIT,
Canada's AQUAREF, CAB Abstract's Aquatic Subset and the Netherlands' DELFT HYDRO
provide more than 607,790 citations and abstracts - oceans of vital water-research
information. Automated thesaurus based searching helps you find any topic with ease.
(description from website)

National Information Services Corporation (NISC)

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.nisc.com
                                                        A4-157

-------
EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Data Source Name

Identification Number
Data Source Description
WATERLIT

236

NISC produces WATERLIT, which has more than 366,480 references to industrial and
environmental aspects of water, wastewater and sanitation. Coverage of Africa is excellent,
as is the analysis of water in arid lands, engineering projects, water quality, water treatment
and international water-related topics. Records are drawn from reports, conference
proceedings and over 760 journals from across the globe. The information dates from 1975
to the present day and about 12,000 new entries are added each year, (description from
website)
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation

Redundancy Explanation
Retrievability Explanation

Source URL
National Information Services Corporation (NISC)

National Information Services Corporation
NISC USA
Wyman Towers, 3100 St. Paul Street,
Baltimore, Maryland 21218 USA
Tel: +1 410 2430797 Fax: +1 410 2430982
Sales: sales@nisc.com
www.nisc.com

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It does not meet considerations because there was no documentation on how the data were
obtained.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.nisc.com/factsheets/gwrw.asp
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation


Completeness Explanation
Redundancy Explanation
WATERNET - American Water Works Association

226

WATERNET provides a comprehensive index of the publications of the American Water
Works Association and the AWWA Research Foundation. Included are books and
proceedings, journals, newsletters, standards, manuals, handbooks, and water quality
standard test methods. Emphasis is on the technical reports and studies from water utilities,
regulatory agencies, and research groups in the United States and its territories, Canada,
Mexico, and Latin America. European and Asian data  are also reported. The database is the
online counterpart to the index to the Journal AWWA from 1971  to the present, and all
AWWA and AWWARF publications from 1973 to the present, with non-AWWA materials
included  on a selective basis, (description from website)

American Water Works Association

American Water Works Association
Information Services Department
6666 W.  Quincy Avenue
Denver, CO 80235
Telephone: 303-794-7711
Telex: 450895 AWWA DVR
Fax:303-794-7310

Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it meets all NDWAC minimum data requirements.

This source is not redundant.
                                                       A4-158

-------
EPA-OGWDW
         Final CCL 3 Chemicals:
        Identifying the Universe
EPA815-R-09-006
      August 2009
Retrievability Explanation

Source URL
This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://librarv.dialoa.com/bluesheets/htmlaa/bl0245.html
Data Source Name
Identification Number

Data Source Description
Proprietor
Contact Information
Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation

Retrievability Explanation

Source URL
Weekly Epidemiological Record (WER)

227

The Weekly Epidemiological Record (WER) is a weekly newsletter published by the World
Health Organization (WHO), intended to keep health professionals informed of international
epidemiological information, particularly concerning outbreaks and emerging infectious
diseases, (description from website)

World Health Organization

World Health Organization
Marketing and  Dissemination
20 Avenue Appia, CH-1211 Geneva 27
Fax: (+4122) 791 4857

Data elements for microbial contaminants

This source does not meet  relevance criteria for the chemical universe because it contains
only information on microbial contaminants.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet  retrievability criteria because the data are not formatted for
automated retrieval.

http ://www. who. i nt/wer/
Data Source Name


Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
WHO Guidelines for Drinking Water Quality: Chemical Aspects:
Index of Chemicals

85

The assessment of the toxicity of drinking-water contaminants has been made on the basis
of published reports from the open literature, information submitted by governments and
other interested parties, and unpublished proprietary data. In the development of the
guideline values, existing international approaches to developing guidelines were carefully
considered. Previous risk assessments developed by the International Programme on
Chemical Safety (IPCS) in Environmental Health Criteria monographs, the International
Agency for Research on Cancer (IARC), the Joint FAO/WHO Meetings on Pesticide
Residues (JMPR), and the Joint FAO/WHO Expert Committee on Food Additives (JECFA)
were reviewed. These assessments were relied upon except where new information justified a
 reassessment. The quality of new data was critically evaluated prior to their use in risk
assessment, (description from website)

World Health Organization

WHO Headquarters
Avenue Appia 20
1211 Geneva 27
Switzerland
Telephone: (+41  22)791 21 11
Facsimile (fax): (+ 41 22) 791  3111
Telex: 415 416
Telegraph: UNISANTE GENEVA
email: info@who.int or library@who.int

Name, synonym, formula, MP, BP, density, VP, water solubility,  Log Kow, odor thresholds,
use, environmental fate, ADI,  CR, GV, IARC cancer class, TDI, NO(A)EL, LO(A)EL, LDx,
HRL, reproductive, embryotoxicity, teratogenicity, mutagenicity
                                                       A4-159

-------
EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does not meet retrievability criteria because the data are not formatted for
automated retrieval.

http://www.who.int/entitv/water sanitation health/dwg/GDW8rev1 and2.pdf
Data Source Name

Identification Number
Data Source Description
Proprietor
Contact Information
Type of Data Elements
Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
WHO Guidelines for Drinking Water Quality: Summary Tables

86

The tables provide a summary of guideline values for approximately 143 microorganisms
and chemicals in drinking-water extracted from the Guidelines for drinking-water quality, 2nd
ed. Vol. 2 Health criteria and other supporting information, 1996 (pp. 940-949) and Addendum
to Vol. 2 . 1998 (pp. 281-283).  Example data elements include Consumer Complaint Level,
Guideline value, Remarks, and Screening value. Guideline values are provided for the
following types of contaminants:  Microbiological, Inorganic, Organic, and Radioactive
constituents, Pesticides, Disinfectants and disinfectant by-products, Chemicals not of
health significance at concentrations normally found in drinking-water constituents, and
Substances that may give rise to complaints from consumers.

Additional summary information not included  in the tables is provided for inorganic and
organic constituents, pesticides, chemicals not of considerable health significance, and
substances leading to complaints from consumers. These summaries provide background
data on the derivation of the guideline values, and may include an IARC assessment of
carcinogenicity, estimated dietary intake, NOAEL, LOAEL, Tolerable Daily Intake (TDI),
Provisional Maximum Tolerable Daily Intake (PMTDI), and reported concentrations of
contaminant in drinking water. The summary  information varies for individual contaminants.
(description from website)

World Health Organization

WHO Headquarters
Avenue Appia 20
1211 Geneva 27
Switzerland
Telephone: (+41 22)791 21 11
Facsimile (fax): (+ 41 22) 791 3111
Telex: 415 416
Telegraph: UNISANTE GENEVA
email: info@who.int or library@who.int

Name, GV, TDI, basis

This source is considered relevant for the CCL Universe because it contains data elements
from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source meets retrievability criteria because it is in tabular format.

http://www.who.int/water sanitation  health/dwa/adwg0506 ann4.pdf
Data Source Name

Identification Number
WHO Recommended Classification of Pesticides by Hazard (CPH)
40
Data Source Description
Pesticide Data Sheets (PDSs) - contain basic information for safe use of pesticides. The
Pesticide Data Sheets are prepared by WHO in collaboration with FAO and give basic
toxicological information on individual pesticides. Priority for issue of PDSs is given to
substances having a wide use in public health programmes and/or in agriculture, or having a
high or an unusual toxicity record. The data sheets are prepared by scientific experts and
                                                        A4-160

-------
EPA-OGWDW
         Final CCL 3 Chemicals:
         Identifying the Universe
EPA815-R-09-006
      August 2009
Proprietor

Contact Information



Type of Data Elements

Relevance Explanation

Completeness Explanation
Redundancy Explanation
Retrievability Explanation

Source URL
peer reviewed. The comments of industry are provided through the industrial association,
GIFAP. The data sheets are revised from time to time as required.

The WHO Recommended Classification of Pesticides by Hazard was approved by the 28th
World Health Assembly in 1975 and has since gained wide acceptance. When it was
published in the WHO Chronicle, 29, 397-401 (1975), an annex, which was not part of the
Classification, illustrated its use by listing examples of classification of some pesticidal
active ingredients and their formulations. Later suggestions were made by Member States
and pesticide registration authorities that further guidance should be given on the
classification of individual pesticides. Guidelines were first issued in 1978, and have since
been revised and  reissued at 2-yearly intervals.
The document is arranged as follows:
Part I: The Classification as recommended by the World Health Assembly. This part is not
subject to periodic review and the classification table and text can only be changed by
resolution of the World Health Assembly.
Part II: Guidelines to Classification. Individual products are classified in a series of tables,
according to the oral or dermal toxicity of the technical product, and its physical state. The
tables are subject to review periodically.
The toxicity values are intended to be a guide only. Formulations should be separately
classified using the methods set out on pages 3 (single technical product) and 6 (mixtures)
and the table in Part I. To assist in the classification of formulations, an annex is now
provided giving numerical tables from which the classification may also be derived.
(description from website)

International Programme for Chemical Safety, World  Health Organization, International
Labour Organisation, United Nations Environment Programme

The International Programme on Chemical Safety (IPCS) is a cooperative venture of the
World Health Organization (WHO), the United Nations Environment Programme (UNEP), and
the International Labour Organisation (ILO). The central unit for IPCS is located at WHO.
webmaster@ccohs.ca

Dose, Critical Effect, BMC,  BMD, ENEV, Cancer Group, TC(A), CTV, ECx, ICx, LCx, LDx,
LO(A)EL, NO(A)EL

This source is considered relevant for the CCL Universe because it contains data elements
derived from toxicological studies.

It meets considerations because it is peer reviewed.

This source is not redundant.

This source does  not meet retrievability criteria  because, with the exception of the
classifications, it is not formatted for automated retrieval.

http://www.inchem.org/documents/pds/pdsother/class.pdf
Data Source Name
Identification Number
Data Source Description
Proprietor
Contact Information
World Health Organization - Information Products Catalogue

230

This Information Products Catalogue provides information on WHO publications produced
since 1948. Its search facility connects the user with information and links the user to the
list of health-related subjects in which WHO publishes, new publications, catalogues and
brochures available online, subscriptions to WHO publications. Links to ordering information,
to the network of WHO sales agents and WHO depository libraries and to the WHO web site
are also provided, (description from website)

World Health Organization

World Health Organization
Marketing and Dissemination
1211 Geneva 27, Switzerland
bookorders@who.int
Type of Data Elements

Relevance Explanation


Completeness Explanation
Bibliographic information, indexing terms, abstracts, chemical names, and CAS Registry
Numbers

This source does not meet relevance criteria because it consists of text (titles and/or
abstracts) on many subjects that may not pertain directly to CCL, and its data elements are
inconsistently presented.

It meets considerations because it is peer reviewed.
                      A4-161

-------
EPA-OGWDW                            Final CCL 3 Chemicals:                        EPA 815-R-09-006
                                         Identifying the Universe                              August 2009
Redundancy Explanation       This source is not redundant.

Retriev ability Explanation      This source does not meet retrievability criteria because the data are not formatted for
                                 automated retrieval.

Source URL                    http://www.who.int/dsa/cat98/chemtox8.htm
                                                     A4-162

-------
EPA-OGWDW                      Final CCL 3 Chemicals:                   EPA 815-R-09-006
                                 Identifying the Universe                        August 2009
                  Appendix 5.  CCL 3 Universe Chemicals
The following table presents the CASRN number and names of the contaminants listed on the draft CCL
3 Universe. The columns to the right summarize the contaminants' progression and status in the CCL 3
process. These chemical contaminants were selected using the process described in the text of the report:
CCL 3 Chemical Documents: Identifying the Universe, EPA 815-R-09-006. This document is posted on
the website (www.epa.gov/safewater) and is also available in the CCL 3 water docket. The list of
contaminants is presented by chemical abstract service registry number (CASRN) when available,
common name, or lastly by aggregate groupings as reported in the data sources considered for the draft
CCL 3.  Further data and information for the contaminants that moved forward in the CCL 3 process are
available in the other technical support documents and Contaminant Information Sheets available in the
CCL 3 water docket.
                                            A5-1

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
5664
50000
50011
50077
50146
50180
50215
50271
50282
50293
50306
50317
50339
50340
50442
50555
50691
50704
50760
50782
50793
50817
50840
50986
50997
51036
51058
51172
51218
51285
51343
51354
51365
51445
51467
51489
51558
51661
51752
51796
52244
52391
52517
52686
52857
52891
52904
53032
53167
53190
53418
53703
53952
53963
54115
54217
54319
54626
54864
55185
55221
55312
55389
55550
55561
55630
55981
56053
56097
56122
56177
56188
56348
56359
56360
56371
56382
56406
56417
56451
56495
56531
56553
56724
56757
56815
56848
56860
56871
56893
56939
57067
57090
57103
57114
Common Name
6041
Formaldehyde
Guanidine hydrochloride
Mitomycin C
Vitamin D2
Cyclophosph amide
Lactic acid
Estriol
Estradiol
p,p'-DDT
2,6-DICHLOROBENZOIC ACID
2,3,6-Trichlorobenzoic acid
3,5-Pyrazolidinedione, 4-butyl-1 ,2-diphenyl-
Propantheline bromide
6H-Purine-6-thione, 1,7-dihydro-
Reserpine
D-Ribose
Sorbitol
Actinomycin D
Aspirin
Benzole acid, 2,5-dichloro-
L-Ascorbic acid
Benzoic acid, 2,4-dichloro-
Ephedrine Hydrochloride
D-Glucose
Piperonyl butoxide
Procaine hydrochloride
1 H-Benzimidazole
5-Fluorouracil
2,4-Dinitrophenol
Scopolamine
L-Proline, 4-hydroxy-, (4R)-
Benzoic acid, 3,5-dichloro-
Benzoic acid, 3,4-dichloro-
1 ,3,6,8-Tetraazatricyclo[4.4.1 .1 3,8]dodecane
Thyroxine
Atropine
Acetamide, N-(4-methoxyphenyl)-
Nitrogen mustard (HN-2)
Urethane
Thiotepa
Aldosterone
Bronopol
Trichlorfon
Famphur
L-Cysteine, hydrochloride
L-Cysteine
Prednisone
Estrone
o,p'-DDD
Androsterone-cis (Testosterone metabolite)
Dibenz[a,h]anthracene
Acetamide, N-9H-fluoren-2-yl-N-hydroxy-
2-Acetylaminofluorene
Nicotine
Benzoic acid, 2-hydroxy-, monosodium salt
Furosemide
Aminopterin
Sodium nicotinate
N-Nitrosodiethylamine (NDEA)
Isonicotinic acid
Epinephrine hydrochloride
Fenthion
Phenol, 4-(methylamino)-, sulfate (2:1) (salt)
Chlorhexidine
Nitroglycerin
1 ,4-Butanediol, dimethanesulfonate
2-Pyrimidinamine, 4,6-dichloro-
2-Amino-6-hydroxy-4(1H)-pyrimidinone
4-Aminobutanoic acid
Ethanamine, 2,2'-dithiobis-, dihydrochloride
1 ,3-Propanediamine, N-(3-aminopropyl)-
Ethanaminium, N,N,N-triethyl-, chloride
Bis(tributylin) oxide
Tributyltin acetate
Benzenemethanaminium, N,N,N-triethyl-, chloride
Parathion
Glycine
L-Alanine
L-Serine
3-Methylcholanthrene
Diethylstilbestrol
Benz[a]anthracene
Coumaphos
Chloramphenicol
Glycerine
L-Aspartic acid
L-Glutamic acid
L-Lysine
L-Cystine
Trimethylbenzylammonium chloride
Allyl isothiocyanate
Cetyl trimethyl ammonium bromide
Hexadecanoic acid
Stearic acid
Nominated
131






Yes
Yes


































Yes




Yes

Yes








Yes



































Draft
PCCL3
532
Yes















Yes

Yes




Yes




Yes









Yes



















Yes





Yes



















Yes








Yes
Final
PCCL3
561
Yes





Yes
Yes








Yes

Yes




Yes




Yes









Yes








Yes










Yes





Yes



















Yes








Yes
Draft
CCL 3
95
Yes





































Yes



















Yes





Yes





























Public
Comment
324
Yes

Yes



Yes
Yes





Yes













Yes














Yes




Yes

Yes



Yes

Yes


Yes






Yes



























Yes
Final
CCL 3
106
Yes





Yes
Yes






























Yes








Yes










Yes





Yes





























CCL 2
40




























Yes

































































CCL1
49




























Yes

































































         A5-2

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
57125
57136
57147
57158
57227
57249
57330
57396
57410
57487
57501
57534
57556
57578
57625
57636
57669
57670
57681
57830
57885
57910
57921
57976
58082
58140
58220
58333
58366
58559
58560
58731
58855
58866
58902
58935
58957
59029
59052
59303
59405
59438
59494
59507
59518
59676
59870
60004
60015
60093
60117
60128
60139
60184
60242
60297
60333
60344
60355
60515
60548
60571
61734
61767
61789
61825
61905
62237
62339
62384
62442
62497
62533
62544
62555
62566
62737
62748
62759
63058
63252
63423
63683
63741
63912
63923
64028
64040
64175
64186
64197
64675
64697
64733
64755
64777
Common Name
Cyanide
Urea
1,1-Dimethylhydrazine
1 ,1 ,1-Trichloro-2-methyl-2-propanol
Vincaleukoblastine, 22-oxo-
Strychnine
Pentobarbital sodium
Aziridine, 1,1',1"-phosphinylidynetris[2-methyl-
Phenytoin
D- Fructose
Sucrose
Meprobamate
Propylene glycol
beta-Propiolactone
Chlortetracycline
Ethinyl Estradiol
Benzoic acid, 4-[(dipropylamino)sulfonyl]-
Sulfaguanidine
Sulfamethazine
progesterone
Cholesterol
17alpha-estradiol
Streptomycin
7,12-Dimethylbenz[a]anthracene
Caffeine
2,4-Pyrimidinediamine, 5-(4-chlorophenyl)-6-ethyl-
testosterone
Promethazine hydrochloride
1 0,1 0'-Oxybisphenoxarsine
1 H-Purine-2,6-dione, 3,7-dihydro-1 ,3-dimethyl-
Pyridoxine hydrochloride
Diphenhydramine
Biotin
D-Xylose
2,3,4,6-Tetrachlorophenol
Hydrochlorothiazide
alpha- Tocopheryl acetate
Vitamin E
Methotrexate
Folic acid
Sulfaquinoxaline
Thiamine
2(3H)-Benzoxazolone
p-Chloro-m-cresol
Methionine
Nicotinic acid
Nitrofurazone
Ethylenediaminetetraacetic acid
Butanoic acid, 1,2,3-propanetriyl ester
4-Aminoazobenzene
4-Dimethylaminoazobenzene
Benzeneethanol
Benzeneethanamine, .alpha.-methyl-, sulfate
L-Tyrosine
Ethanol, 2-mercapto-
Ethyl ether
9,12-Octadecadienoic acid (9Z.12Z)-
Methyl hydrazine
Acetamide
Dimethoate
Tetracycline (internal use)
Dieldrin
Methylene blue
Phenylephrine hydrochloride
Glycine, N-(4-aminobenzoyl)-
Am it role
L-Leucine
p-Nitrobenzoic acid
Edetate calcium disodium (anhydrous)
Phenylmercury acetate
Phenacetin
Ethanaminium, 2-hydroxy-N,N,N-trimethyl-
Aniline
Acetic acid, calcium salt
Thioacetamide
Thiourea
Dichlorvos
Sodium fluoroacetate
N-nitrosodimethylamine (NDMA)
ANDROSTENEDIONE
Carbaryl
D-Glucose, 4-O-.beta.-D-galactopyranosyl-
L-Methionine
Sulfanilamide
L-Phenylalanine
Benzylamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-
Tetrasodium EDTA
Benzeneethanamine
Ethanol
Formic acid
Acetic acid
Diethyl sulfate
lodoacetic acid
Demeclocycline hydrochloride (internal use)
Tetracycline hydrochloride
Tolbutamide
Nominated














Yes
Yes


Yes
Yes
Yes
Yes




Yes

































Yes















Yes

Yes

Yes















Draft
PCCL3

Yes






Yes



Yes


































Yes










Yes
Yes

Yes







Yes


Yes



Yes
Yes
Yes

Yes





Yes

Yes
Yes
Yes
Yes




Final
PCCL3

Yes






Yes



Yes


Yes





Yes
















Yes








Yes










Yes
Yes

Yes







Yes


Yes



Yes
Yes
Yes

Yes





Yes

Yes
Yes
Yes
Yes




Draft
CCL 3


























































Yes
Yes












Yes





Yes

















Public
Comment








Yes


Yes


Yes
Yes


Yes
Yes
Yes
Yes


Yes

Yes




Yes



Yes


Yes




Yes

Yes

Yes












Yes
Yes








Yes

Yes



Yes

Yes
Yes
Yes











Yes



Final
CCL 3















Yes





Yes




































Yes
Yes












Yes





Yes

















CCL 2
































































































CCL1





























































Yes


































         A5-3

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
65305
65452
65496
65714
65850
66228
66251
66717
66728
66751
66842
67038
67209
67436
67458
67481
67527
67561
67630
67641
67685
67710
67721
67970
68042
68111
68122
68199
68224
68268
68360
68768
68940
69658
69727
69794
70111
70304
70553
71001
71238
71307
71363
71410
71487
71636
71910
72140
72173
72184
72195
72333
72480
72548
72559
72560
72571
73223
73245
73314
73325
73405
74113
74317
74793
74839
74851
74862
74873
74884
74895
74931
74942
74953
74964
74975
74997
75003
75025
75047
75058
75070
75081
75105
75127
75150
75161
75183
75207
75218
75230
75263
75285
75296
75310
75332
Common Name
Nicotine sulfate
Benzamide, 2-hydroxy-
Benzoic acid, 4-amino-2-hydroxy-
2,4(1 H,3H)-Pyrimidinedione, 5-methyl-
Benzoic acid
2,4(1 H,3H)-Pyrimidinedione
Hexaldehyde
1,10-Phenanthroline
PYRIDOXAL
Uracil mustard
Glucosamine hydrochloride
Thiamine hydrochloride
Nitrofurantoin
Glycine, N,N-bis[2-[bis(carboxymethyl)amino]ethyl]-
Furazolidone
Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, chloride
2,4,6(1H,3H,5H)-Pyrimidinetrione
Methanol
Isopropanol
Acetone
Dimethyl sulfoxide
Methane, sulfonylbis-
Hexachloroethane
Cholecalciferol
Sodium citrate anhydrous
Mercaptoacetic acid
N,N-Dimethylformamide
Vitamin B12
Noreth in drone (1 9-Norethisterone)
Retinol
Benzene, 1 ,4-bis(trichloromethyl)-
Triaziquone
6H-Purin-6-one, 1,7-dihydro-
D-Mannitol
Salicylic acid
Maltose
Ethanone, 2-bromo-1-phenyl-
Hexachlorophene
Benzenesulfonamide, 4-methyl-
L-Histidine
1-Propanol
Cytosine
1-Butanol
1-Pentanol
Acetic acid, cobalt(2+) salt
Digitoxin
Ethanaminium, N,N,N-triethyl-, bromide
Sulfathiazole
Propanoic acid, 2-hydroxy-, monosodium salt
L-Valine
L-Threonine
Mestranol
9,10-Anthracenedione, 1,2-dihydroxy-
p,p'-DDD
p,p'-DDE
Ethylan
Trypan blue
L-Tryptophan
1H-Purin-6-amine
MELATONIN
L-lsoleucine
6H-Purin-6-one, 2-amino-1 ,7-dihydro-
p-Chlorobenzoic acid
1 ,4-Benzenediamine, N,N'-diphenyl-
L-Arginine
Methyl bromide (Bromomethane)
Ethylene
Acetylene
Chloromethane (Methyl chloride)
Methyl iodide
Methylamine
Methyl mercaptan
Boron, trihydro(N-methylmethanamine)-, (T-4)-
Dibromomethane
Bromoethane
Halon 1011(bromochloromethane)
Propyne
Chloroethane
Vinyl fluoride
Ethylamine
Acetonitrile
Acetaldehyde
Ethyl mercaptan
HFC-32
Formamide
Carbon disulfide
Magnesium, bromomethyl-
Dimethyl sulfide
Calcium carbide
Ethylene oxide
Boron, (ethanamine)trifluoro-, (T-4)-
Propane, 2-bromo-
Isobutane
2-Chloropropane
Isopropylamine
2-Propanethiol
Nominated




























Yes


















Yes



Yes












































Draft
PCCL3




Yes












Yes
Yes
Yes


Yes


Yes














Yes

Yes
Yes










Yes










Yes


Yes

Yes
Yes

Yes
Yes
Yes

Yes
Yes
Yes
Yes
Yes



Yes



Yes




Yes

Final
PCCL3




Yes












Yes
Yes
Yes


Yes


Yes


Yes











Yes

Yes
Yes







Yes


Yes










Yes


Yes

Yes
Yes

Yes
Yes
Yes

Yes
Yes
Yes
Yes
Yes



Yes



Yes




Yes

Draft
CCL 3

















Yes
























Yes






















Yes


Yes












Yes







Yes






Public
Comment




Yes












Yes

Yes








Yes





Yes












Yes



Yes

Yes











Yes


Yes




Yes

Yes





Yes



Yes



Yes






Final
CCL 3

















Yes










Yes













Yes








Yes













Yes


Yes






Yes





Yes







Yes






CCL 2






















































Yes










Yes






























CCL1






















































Yes










Yes






























         A5-4

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
75343
75365
75376
75387
75434
75445
75456
75467
75478
75503
75525
75547
75558
75569
75570
75592
75627
75638
75649
75650
75661
75683
75694
75718
75729
75730
75741
75752
75774
75785
75796
75832
75843
75854
75865
75876
75887
75912
75945
75956
75967
75978
75989
76017
76028
76051
76062
76120
76131
76142
76153
76197
76222
76255
76391
76573
76835
76879
76937
77065
77098
77485
77496
77532
77543
77587
77623
77656
77714
77736
77758
77781
77792
77838
77850
77861
77894
77907
77918
77929
77930
77941
77996
78002
78046
78080
78104
78115
78137
78217
78239
78273
78320
78331
78342
78386
Common Name
1,1-Dichloroethane
Acetyl chloride
HFC-152a
Vinylidene fluoride
HCFC-21
Phosgene
HCFC-22
HFC-23
Methane, triiodo-
Trimethylamine
Nitromethane
Silane, dichloromethyl-
Propyleneimine
Oxirane, methyl-
Tetramethylammonium chloride
Tetramethylammonium hydroxide
Bromotrichloromethane
Halon 1301
tert-Butylamine
tert-Butanol
2-Propanethiol, 2-methyl-
HCFC-142b
CFC-11
CFC-12
CFC-13
Methane, tetrafluoro-
Tetramethyllead
Methanesulfonic acid
Trimethylchlorosilane
Dimethyldichlorosilane
Methyltrichlorosilane
Butane, 2,2-dimethyl-
1-Propanol, 2,2-dimethyl-
2-Methyl-2-butanol
Acetone cyanohydrin
Chloral
HCFC-133a
tert-Butyl hydroperoxide
Silane, trichloroethenyl-
HALOGENATED ETHANES CS (PENTABROMOETHANE)
Tribromoacetic acid (TBAA)
2-Butanone, 3,3-dimethyl-
Pivalic acid
Pentachloroethane
Trichloroacetyl chloride
Acetic acid, trifluoro-
Chloropicrin
Ethane, 1,1,2,2-tetrachloro-1,2-difluoro-
CFC-113
CFC-11 4
CFC-11 5
Propane, octafluoro-
Camphor
Triamcinolone acetonide
1-Propanol, 2-methyl-2-nitro-
Codeine
Benzene, 1 ,1 ', 1 "-(chloromethylidyne)tris-
Triphenyltin hydroxide (TPTH)
Benzilic acid
Gibberellic acid
Phenolphthalein
1,3-Dibromo-5,5-dimethylhydantoin
2-Methyl-2-nitro-1,3-propanediol
Cedrol
Cedrol, acetate
Stannane, dibutylbis[(1-oxododecyl)oxy]-
2,2'-Methylenebis[6-(1-methylcyclohexyl)-p-cresol]
Butanamide, N-(aminocarbonyl)-2-bromo-2-ethyl-
5,5-Dimethylhydantoin
Dicyclopentadiene
3-Methyl-1-pentyn-3-ol
Dimethyl sulfate
Thiophene, 2,5-dihydro-, 1,1-dioxide
Ethyl methylphenylglycidate
1 ,1 ,1-Tris(hydroxymethyl)ethane
Tris(hydroxymethyl)aminomethane
Acetyl triethyl citrate
2-Acetyltributylcitrate
Choline dihydrogen citrate
Citric acid
Ethyl citrate
Tributyl citrate
Trimethylolpropane
Tetraethyl lead
1 ,3,2-Dioxastannepin-4,7-dione, 2,2-dibutyl-
Silane, ethenyltriethoxy-
Silicic acid (H4SIO4), tetraethyl ester
Pentaerythritol tetranitrate
Silicic acid (H4SIO4), tetrakis(2-ethylbutyl) ester
Morpholinium, 4-ethyl-4-hexadecyl-, ethyl sulfate
Pentaerythritol monostearate
Cyclohexanol, 1-ethynyl-
Phosphoric acid, tris(4-methylphenyl) ester
Phenol, 4-(1,1-dimethylethyl)-, phosphate (3:1)
Dioxathion
Phosphonic acid, ethyl-, diethyl ester
Nominated



















Yes













Yes

Yes




Yes





Yes








Yes








































Draft
PCCL3
Yes





Yes


Yes
Yes


Yes
Yes
Yes


Yes
Yes


Yes
Yes





Yes
Yes



Yes

Yes
Yes





Yes


Yes










Yes


Yes
Yes







Yes

Yes







Yes


Yes
Yes












Final
PCCL3
Yes





Yes


Yes
Yes


Yes
Yes
Yes


Yes
Yes


Yes
Yes





Yes
Yes



Yes

Yes
Yes


Yes


Yes


Yes










Yes


Yes
Yes







Yes

Yes







Yes


Yes
Yes












Draft
CCL 3
Yes





Yes






Yes











































Yes






































Public
Comment
Yes







Yes










Yes













Yes

Yes




Yes





Yes





Yes


Yes
























Yes















Final
CCL 3
Yes





Yes






Yes











































Yes






































CCL 2
Yes































































































CCL1
Yes































































































         A5-5

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
78400
78422
78444
78466
78488
78502
78513
78591
78626
78637
78671
78706
78717
78762
78773
78784
78795
78819
78820
78831
78842
78853
78864
78886
78897
78900
78922
78933
78944
78955
78966
78977
78988
79027
79049
79072
79094
79107
79141
79163
79196
79209
79210
79221
79243
79276
79301
79312
79345
79367
79389
79390
79403
79414
79447
79469
79572
79743
79787
79812
79925
79947
79969
80057
80079
80080
80091
80104
80159
80171
80182
80251
80262
80397
80433
80466
80488
80513
80524
80546
80568
80580
80626
81049
81072
81118
81130
81141
81152
81163
81209
81210
81243
81254
81301
81334
Common Name
Phosphoric acid, triethyl ester
Phosphoric acid, tris(2-ethylhexyl) ester
Carisoprodol
Dibutyl butylphosphonate
Tributes
Phosphine oxide, trioctyl-
Ethanol, 2-butoxy-, phosphate (3:1)
Isophorone
Silane, diethoxydimethyl-
Varox
Propanenitrile, 2,2'-azobis[2-methyl-
3,7-Dimethyl-1 ,6-octadien-3-ol
3,3-Bis(chloromethyl)oxetane
Butane, 2-bromo-
Propane, 1-bromo-2-methyl-
2-Methylbutane
Isoprene
Isobutylamine
Isobutyronitrile
Isobutanol
Isobutyraldehyde
2-Propenal, 2-methyl-
Butane, 2-chloro-
2,3-Dichloropropene
2-Chloro-1-propanol
1 ,2-Propanediamine
2-Butanol
Methyl ethyl ketone
Methyl vinyl ketone
2-Propanone, 1-chloro-
2-Propanol, 1-amino-
Lactonitrile
Methylglyoxal
dichloroacetaldehyde
Chloroacetyl chloride
Chloroacetamide
Propionic acid
Acrylic acid
Glycolic acid
Acetamide, N-methyl-
Thiosemicarbazide
Methyl acetate
Peracetic acid
Methyl chlorocarbonate
Nitroethane
Ethane, 1,1,2,2-tetrabromo-
Propanoyl chloride, 2-methyl-
Isobutyric acid
1,1,2,2-Tetrachloroethane
Dichloroacetyl chloride
Chlorotrifluoroethylene
Methacrylamide
Ethanedithioamide
Methacrylic acid
Dimethylcarbamoyl chloride
2-Nitropropane
Oxytetracycline
1,4-Benzenediol, 2,5-bis(1,1-dimethylpropyl)-
Allyl alpha-ionone
Retinol, hexadecanoate
Bicyclo[2.2.1]heptane, 2,2-dimethyl-3-methylene-
Tetrabromobisphenol A
Phenol, 4,4'-(1-methylethylidene)bis[2-(1 ,1-dimethylethyl)-
Bisphenol A (4,4'-lsopropylidenediphenol)
4,4'-Dichlorodiphenyl sulfone
Benzenamine, 4,4'-sulfonylbis-
Phenol, 4,4'-sulfonylbis-
Silane, dichlorodiphenyl-
Cumene hydroperoxide
Benzenesulfonic acid, hydrazide
Benzenesulfonic acid, methyl ester
Acetic acid, dihydroterpinyl ester
alpha- Terpinyl acetate
Benzenesulfonamide, N-ethyl-4-methyl-
Peroxide, bis(1-methyl-1-phenylethyl)
p-tert-Amylphenol
Methyl p-methylbenzenesulfonate
Benzenesulfonic acid, 4,4'-oxybis-, dihydrazide
p-Menthane-1 ,8-diyldiamine
Lilial
alpha- Pinene
2-bromobutanoic acid
Methyl methacrylate
1,5-Naphthalenedisulfonic acid
Saccharin
Amsonic acid
(+)-Panthenol
Musk ketone
Muskxylene
2-Amino-1-naphthalenesulfonic acid
Benzene, 1 ,3-dimethyl-2-nitro-
Dicyclopentadiene dioxide
Taurocholic acid
Cholic acid
Naphthalenetetracarboxylic dianhydride
Perylimid
Nominated

































Yes






















Yes






Yes
































Draft
PCCL3




Yes










Yes
Yes

Yes
Yes




Yes






Yes


Yes

Yes
Yes



Yes






Yes


Yes

Yes

Yes








Yes



Yes













Yes













Final
PCCL3




Yes










Yes
Yes

Yes
Yes




Yes






Yes

Yes
Yes

Yes
Yes



Yes






Yes


Yes

Yes

Yes







Yes
Yes



Yes













Yes













Draft
CCL 3




Yes































































Yes



























Public
Comment







Yes



















Yes

Yes


Yes
Yes

Yes




















Yes






Yes

















Yes














Final
CCL 3




Yes































































Yes



























CCL 2
















































Yes















































CCL1
















































Yes















































         A5-6

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
81481
81492
81550
81618
81630
81641
81776
81812
81845
81889
82053
82213
82280
82348
82382
82440
82451
82666
82688
83261
83329
83341
83409
83443
83465
83567
83669
83670
83794
83863
83885
84151
84515
84582
84617
84628
84640
84651
84662
84695
84720
84742
84753
84764
84775
84786
84833
85018
85029
85223
85405
85416
85438
85449
85529
85609
85687
85698
85701
85712
85836
85916
85983
86259
86260
86282
86306
86500
86555
86577
86657
86737
86748
86862
86873
86920
86931
86986
87014
87025
87138
87183
87194
87207
87252
87296
87332
87412
87445
87569
87592
87605
87616
87627
87650
87661
Common Name
C.I. Solvent Violet 13
1 -Amino-2,4-dibromoanthraquinone
9,10-Anthracenedione, 1,8-dihydroxy-4,5-dinitro-
9,10-Anthracenedione, 1,2,5,8-tetrahydroxy-
9,10-Anthracenedione, 1,4-diamino-2,3-dihydro-
9,10-Anthracenedione, 1,4-dihydroxy-
C.l. Pigment Blue 60
Warfarin
1 ,8-Naphthalic anhydride
Rhodamine B
7H-Benz[de]anthracen-7-one
9,10-Anthracenedione, 1,5-diphenoxy-
1 -Amino-2-methylanthraquinone
9,10-Anthracenedione, 1-nitro-
C.l. Disperse Red 9
9,10-Anthracenedione, 1-chloro-
9,10-Anthracenedione, 1-amino-
Diphacinone
Pentachloronitrobenzene
Pindone
Acenaphthene
1 H-lndole, 3-methyl-
Benzoic acid, 2-hydroxy-3-methyl-
Deoxycholic acid
beta-sitosterol
1 ,5-Naphthalenediol
Benzene, 1-(1 ,1-dimethylethyl)-2-methoxy-4-methyl-3,5-
1 H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-
Rotenone
Phytic acid
Riboflavin
1,1':2',1"-Terphenyl
9,10-Anthracenedione, 2-ethyl-
Dichlorodicyanobenzoquinone
Dicyclohexyl phthalate
Diphenyl phthalate
Butyl cyclohexyl phthalate
Anthraquinone
Diethyl phthalate
Diisobutyl phthalate
Ethoxycarbonylmethyl ethyl phthalate
Dibutyl phthalate
Dihexyl phthalate
Dinonyl phthalate
1 ,2-Benzenedicarboxylic acid, didecyl ester
1 ,2-Benzenedicarboxylic acid, butyl octyl ester
Tribasenaldehyde
Phenanthrene
Benzo[f]quinoline
Benzene, pentabromoethyl-
1 H-lsoindole-1 ,3(2H)-dione, 3a,4,7,7a-tetrahydro-
Phthalimide
Tetrahydrophthalic anhydride
Phthalic anhydride
Benzole acid, 2-benzoyl-
4,4'-Butylidenebis[6-tert-butyl-m-cresol]
Butyl benzyl phthalate
Butyl 2-ethylhexyl phthalate
2-Butoxy-2-oxoethyl butyl phthalate
Methyl carbethoxymethyl phthalate
C.I. Solvent Red 24
Benzole acid, 2-(methylamino)-, methyl ester
Urea, N,N'-diethyl-N,N'-diphenyl-
MONOOCTYLDIPHENYLAMINE
1,1'-Biphenyl, 2-methoxy-
9H-Carbazole, 9-ethyl-
N-Nitrosodiphenylamine (NDPhA)
Azinphos-methyl
1-Naphthoicacid
1-Nitronaphthalene
Amido-G-acid
Fluorene
Carbazole
1-Naphthaleneacetamide
1-Naphthaleneacetic acid
3-Methyl-1-p-tolyl-5-pyrazolone
1 -Phenyl-5-mercaptotetrazole
4, 7-Dichloroqu incline
7-Dimethylamino-4-methylcoumarin
7-Amino-4-hydroxy-2-naphthalenesulfonic acid
Diethyl (ethoxymethylene)malonate
p-tert-Butylphenyl salicylate
Benzole acid, 2-hydroxy-, 2-methylpropyl ester
Benzole acid, 2-hydroxy-, 3-methylbutyl ester
Benzole acid, 2-amino-, ethyl ester
2-Propen-1-ol, 3-phenyl-, 2-aminobenzoate
Isosorbide dinitrate
1(3H)-lsobenzofuranone
Caryophyllene
2-Butenoic acid, 2,3-dichloro-4-oxo-, (2Z)-
Benzenamine, 2,3-dimethyl-
Benzenamine, 3-chloro-2-methyl-
1 ,2,3-Trichlorobenzene
2,6-Xylidine
2,6-Dichlorophenol
1,2,3-Benzenetriol
Nominated







Yes






























Yes


Yes














Yes










Yes




























Draft
PCCL3

Yes






















































Yes









Yes
Yes
























Yes
Yes


Final
PCCL3

Yes






















































Yes









Yes
Yes
























Yes
Yes


Draft
CCL 3


































































Yes





























Public
Comment







Yes













Yes


Yes









Yes



Yes


Yes





Yes








Yes









Yes
Yes



Yes
Yes
















Yes






Final
CCL 3


































































Yes





























CCL 2
































































































CCL1
































































































         A5-7

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
87672
87683
87694
87796
87810
87821
87832
87843
87898
87901
87990
88040
88062
88095
88108
88120
88142
88186
88197
88211
88244
88266
88277
88302
88415
88448
88459
88517
88539
88584
88608
88619
88631
88642
88653
88686
88697
88722
88733
88744
88755
88891
88960
88982
88993
89009
89043
89054
89087
89190
89258
89281
89327
89587
89612
89623
89634
89656
89725
89758
89781
89805
89816
89838
89861
89985
90006
90017
90028
90040
90051
90120
90153
90164
90175
90302
90437
90517
90642
90722
90802
90824
90948
90982
91087
91156
91167
91178
91203
91225
91236
91407
91441
91496
91510
91532
Common Name
Choline bitartrate
Hexachlorobutadiene
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-
L-Sorbose
D-Tagatose
Benzene, hexabromo-
Benzene, pentabromomethyl-
Cyclohexane, 1 , 2,3,4, 5-pentabromo-6-chloro-
myo-lnositol
Trichloro-s-triazinetrione
Xylitol
4-Chloro-3,5-dimethylphenol
2,4,6-Trichlorophenol
2-Ethylbutyric acid
Diethylcarbamoyl chloride
2-Pyrrolidinone, 1-ethenyl-
2-Furancarboxylic acid
Phenol, 2-(1,1-dimethylethyl)-
Benzenesulfonamide, 2-methyl-
Benzenesulfonic acid, 2-amino-
2,2'-Methylenebis(ethyl-6-tert-butylphenol)
alpha- Hydroxy-2,6-di-tert-butyl-p-cresol
2,6-Di-tert-butyl-.alpha.-(dimethylamino)-p-cresol
3-Trifluoromethyl-4-nitrophenol
Cyclohexanol, 2-(1,1-dimethylethyl)-, acetate
Benzenesulfonic acid, 2-amino-5-methyl-
Benzenesulfonic acid, 2,5-diamino-
Benzenesulfonic acid, 2-amino-4-chloro-5-methyl-
Benzenesulfonic acid, 2-amino-5-chloro-4-methyl-
1,4-Benzenediol, 2,5-bis(1,1-dimethylethyl)-
6-tert-Butyl-m-cresol
2,4-Xylenesulfonic acid
Benzenesulfonic acid, 2,4-diamino-
Benzenesulfonic acid, 4-(acetylamino)-2-amino-
Benzoic acid, 2-bromo-
Benzamide, 2-amino-
Phenol, 2-(1-methylethyl)-
o-Nitrotoluene
o-Chloronitrobenzene
o-Nitroaniline
o-Nitrophenol
Picric acid
1 ,2-Benzenedicarboxamide
4-Cyclohexene-1 ,2-dicarboxylic acid
Phthalic acid
Quinolinic acid
1 ,2,4-Benzenetricarboxylic acid, trioctyl ester
Pyromellitic acid
1 ,2-Benzenedicarboxylic acid, 4-sulfo-
1 ,2-Benzenedicarboxylic acid, butyl decyl ester
3H-Pyrazol-3-one, 2,4-dihydro-5-methyl-2-phenyl-
6-Dodecyl-1,2-dihydro-2,2,4-trimethylquinoline
1 H,3H-Benzo[1 ,2-c:4,5-c']difuran-1 ,3,5,7-tetrone
Benzene, 1 ,4-dimethyl-2-nitro-
Benzene, 1,4-dichloro-2-nitro-
Benzenamine, 4-methyl-2-nitro-
Benzenamine, 4-chloro-2-nitro-
D-erythro-Hex-2-enonic acid, . gamma. -lactone
Phenol, 2-(1-methylpropyl)-
Benzoyl chloride, 2,4-dichloro-
Racementhol
Menthone
2-Cyclohexen-1-one, 3-methyl-6-(1-methylethyl)-
Thymol
Benzole acid, 2,4-dihydroxy-
Benzaldehyde, 2-chloro-
Phenol, 2-ethyl-
2-Hydroxybenzenemethanol
Benzaldehyde, 2-hydroxy-
o-Anisidine
Guaiacol
1-Methylnaphthalene
1-Naphthol
1 ,2,3-Benzotriazin-4(1 H)-one
Rosacetol
1-Naphthalenamine, N-phenyl-
2-Phenylphenol
2-Naphthalenesulfonic acid, 6-amino-4-hydroxy-
Benzeneacetic acid, .alpha.-hydroxy-
Phenol, 2,4,6-tris[(dimethylamino)methyl]-
D-Gluconic acid, .delta.-lactone
Pseudoephedrine
Michler's ketone
4,4'-Dichlorobenzophenone
Toluene-2,6-diisocyanate
1 ,2-Benzenedicarbonitrile
Benzene, 1 ,2-dimethoxy-
Decahydronaphthalene
Naphthalene
Quinoline
o-Nitroanisole
Phenylanthranilic acid
4-Methyl-7-diethylaminocoumarin
N-Butylacetanilide
Lilial-methylanthranilate, Schiffs base
Ethoxyquin
Nominated







































































Yes
















Yes







Draft
PCCL3

Yes










Yes
























Yes
Yes





Yes











































Yes
Yes






Final
PCCL3

Yes










Yes
























Yes
Yes





Yes











































Yes
Yes






Draft
CCL 3

























































































Yes






Public
Comment












Yes



























Yes



Yes















Yes















Yes











Yes







Final
CCL 3

























































































Yes






CCL 2












Yes



















































































CCL1

Yes










Yes











































































Yes







         A5-8

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
91565
91576
91587
91598
91623
91634
91645
91656
91667
91678
91689
91769
91849
91872
91930
91941
91952
91974
92068
92159
92364
92433
92444
92488
92499
92524
92591
92648
92660
92671
92693
92706
92773
92842
92875
92886
92911
92933
92944
93027
93049
93083
93130
93141
93152
93163
93185
93265
93356
93458
93469
93538
93550
93583
93607
93629
93652
93685
93696
93709
93710
93765
93834
93890
93925
94042
94097
94111
94133
94202
94268
94280
94360
94462
94520
94586
94597
94600
94677
94746
94804
94815
94826
94860
94917
94962
95012
95067
95136
95147
95169
95192
95294
95318
95329
95330
Common Name
Isatin
2-Methylnaphthalene
2-Chloronaphthalene
2-Naphthalenamine
6-Methylquinoline
Quinaldine
Coumarin
Cyclohexanamine, N,N-diethyl-
Benzenamine, N,N-diethyl-
Benzenamine, N,N-diethyl-3-methyl-
Phenol, S-(diethylamino)-
1 ,3,5-Triazine-2,4-diamine, 6-phenyl-
Mepyramine
Benzene, [2-(dimethoxymethyl)-1-heptenyl]-
3,3'-Dimethoxybenzidine-4,4'-diisocyanate
3,3'-Dichlorobenzidine
[l.l'-Biphenyll-S.S'.M'-tetramine
3,3'-Dimethyl-4,4'-diphenylene diisocyanate
1,1':3',1"-Terphenyl
Butanamide, N-(2-methoxyphenyl)-3-oxo-
Benzenamine, 4-(6-methyl-2-benzothiazolyl)-
3-Pyrazolidinone, 1-phenyl-
2,3-Naphthalenediol
2H-1-Benzopyran-2-one, 6-methyl-
Benzenamine, N-(2-chloroethyl)-N-ethyl-
Biphenyl
Benzenemethanamine, N-ethyl-N-phenyl-
Propanenitrile, 3-[(2-hydroxyethyl)phenylamino]-
1,1'-Biphenyl, 4-bromo-
4-Aminobiphenyl
4-Phenylphenol
3-Hydroxy-2-naphthoic acid
3-Hydroxy-2-naphthanilide
Phenothiazine
Benzidine
[1,1'-Biphenyl]-4,4'-diol
p-Phenylacetophenone
4-Nitrobiphenyl
1,1':4',1"-Terphenyl
Benzaldehyde, 2,5-dimethoxy-
Naphthalene, 2-methoxy-
Ethanone, 1-(2-naphthalenyl)-
Methanesulfonic acid, [(2-methoxyphenyl)amino]-
1 ,2-Propanediol, 3-(2-methoxyphenoxy)-
Methyleugenol
Benzene, 1 ,2-dimethoxy-4-(1-propenyl)-
Naphthalene, 2-ethoxy-
Acetamide, N-(2-methoxyphenyl)-
UMBELLIFERONE
Phenol, 4-(2-naphthalenylamino)-
1 ,4-Benzenediamine, N,N'-di-2-naphthalenyl-
Benzeneacetaldehyde, .alpha.-methyl-
1-Propanone, 1-phenyl-
Benzoic acid, methyl ester
Methyl nicotinate
N-(2-Hydroxyethyl)iminodiacetic acid
Mecoprop
Butanamide, N-(2-methylphenyl)-3-oxo-
Imidodicarbonimidic diamide, N-(2-methylphenyl)-
Butanamide, N-(2-chlorophenyl)-3-oxo-
Allidochlor
2,4,5-T
9-Octadecenamide, N,N-bis(2-hydroxyethyl)-, (9Z)-
Ethyl benzoate
Benzenemethanol, .alpha.-methyl-, acetate
Hexanoic acid, 2-ethyl-, ethenyl ester
Benzocaine
2,4-D, isopropyl ester
Benzole acid, 4-hydroxy-, propyl ester
Chlorpropamide
Benzole acid, 4-hydroxy-, butyl ester
Triethylene glycol di(2-ethylhexoate)
Benzoyl peroxide
1-Butanol, 3-methyl-, benzoate
1 H-Benzimidazole, 5-nitro-
Dihydrosafrole
Safrole
Dimethyl hexahydroterephthalate
Salicylaldoxime
MCPA
2,4-D, butyl ester
MCPB
2,4-DB
Phenol, 2-ethoxy-5-(1-propenyl)-
. alpha.,. alpha. '-(Propylenedinitrilo)di-o-cresol
2-Ethyl-1 ,3-hexanediol
Benzaldehyde, 2,4-dihydroxy-
Sulfallate
1H-lndene
Benzotriazole
Benzothiazole
1 H-lmidazole-1-ethanol, 2-heptadecyl-4,5-dihydro-
N,N-Diisopropyl-2-benzothiazolesulfenamide
Benzothiazolyl-2-tert-butylsulfenamide
Benzothiazole, 2-(4-morpholinyldithio)-
2-Benzothiazolesulfenamide, N-cyclohexyl-
Nominated

Yes






















































Yes







































Draft
PCCL3



Yes


Yes








Yes













Yes




Yes









Yes


































Yes









Yes






Final
PCCL3



Yes


Yes








Yes













Yes




Yes









Yes


































Yes









Yes






Draft
CCL 3
































































































Public
Comment


Yes

































































Yes



























Final
CCL 3
































































































CCL 2
































































































CCL1
































































































         A5-9

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
95385
95396
95487
95498
95512
95534
95545
95556
95567
95578
95636
95647
95658
95681
95692
95705
95716
95749
95761
95772
95783
95794
95807
95829
95830
95852
95874
95885
95921
95932
95943
95954
95965
96059
96082
96093
96106
96139
96140
96173
96184
96195
96208
96220
96231
96242
96264
96275
96297
96311
96322
96333
96344
96377
96457
96479
96480
96491
96504
96548
96695
96708
96753
96764
96913
96968
96991
97007
97029
97052
97096
97234
97369
97392
97416
97529
97530
97541
97596
97610
97621
97632
97643
97654
97723
97745
97778
97803
97847
97858
97869
97881
97905
97938
97949
97950
Common Name
Oleyl hydroxyethyl imidazoline
5-Norbornene-2-methylolacrylate
o-Cresol
o-Chlorotoluene
o-Chloroaniline
o-Toluidine
1,2-Phenylenediamine
Phenol, 2-amino-
Phenol, 2-bromo-
o-Chlorophenol
1 ,2,4-Trimethylbenzene
Benzenamine, 3,4-dimethyl-
Phenol, 3,4-dimethyl-
Benzenamine, 2,4-dimethyl-
Benzenamine, 4-chloro-2-methyl-
1 ,4-Benzenediamine, 2-methyl-
1 ,4-Benzenediol, 2-methyl-
3-Chloro-p-toluidine
3,4-Dichloroaniline
Phenol, 3,4-dichloro-
Benzenamine, 2,5-dimethyl-
5-Chloro-o-toluidine
2,4-Toluenediamine
2,5-Dichloroaniline
4-Chloro-1 ,2-diaminobenzene
Phenol, 2-amino-4-chloro-
2,5-Xylenol
1 ,3-Benzenediol, 4-chloro-
Ethyl oxalate
Benzene, 1,2,4,5-tetramethyl-
1 ,2,4,5-Tetrachlorobenzene
2,4,5-Trichlorophenol
Dilactide
2-Propenoic acid, 2-methyl-, 2-propenyl ester
Limonene dioxide
Styrene oxide
Aluminum, chlorodiethyl-
2,3-Dibromopropanol
Pentane, 3-methyl-
Butanal, 2-methyl-
1 ,2,3-Trichloropropane
1-Propene, 1 ,2,3-trichloro-
1-Butanol, 2-amino-
3-Pentanone
1 ,3-Dichloro-2-propanol
alpha-Chlorohydrin
2-Propanone, 1 ,3-dihydroxy-
Monothioglycerol
Furfuryl alcohol
Picolinic acid
Can/one
Methyl acrylate
Acetic acid, chloro-, methyl ester
Cyclopentane, methyl-
Ethylenethiourea
Furan, tetrahydro-2-methyl-
gamma-Butyrolactone
1 ,3-Dioxolan-2-one
2-Thiazolamine
1H-Pyrrole, 1-methyl-
4,4'-Thiobis(6-tert-butyl-m-cresol)
Phenol, 2-(1,1-dimethylethyl)-4-ethyl-
Benzenesulfonic acid, 2-amino-5-nitro-
Phenol, 2,4-bis(1 ,1-dimethylethyl)-
Phenol, 2-amino-4,6-dinitro-
Benzenamine, 4-methoxy-2-nitro-
Benzoic acid, 4-chloro-3-nitro-
2,4-Dinitrochlorobenzene
Benzenamine, 2,4-dinitro-
Benzoic acid, 2-hydroxy-5-sulfo-
Benzenesulfonamide, 4-chloro-3-nitro-
Dichlorophene
Butanamide, N-(2,4-dimethylphenyl)-3-oxo-
Guanidine, N,N'-bis(2-methylphenyl)-
Ethyl chrysanthemate
Benzenamine, 2-methoxy-4-nitro-
Eugenol
Phenol, 2-methoxy-4-(1-propenyl)-
Allantoin
Pentanoic acid, 2-methyl-
Propanoic acid, 2-methyl-, ethyl ester
Ethyl methacrylate
Propanoic acid, 2-hydroxy-, ethyl ester
Butanedioic acid, methylene-
Propanoic acid, 2-methyl-, anhydride
Bis(dimethylthiocarbamoyl) sulfide
Disulfiram
N- Methyl- N-oleoyltaurine
1 ,3-Butanediamine, N,N,N',N'-tetramethyl-
Propanoic acid, 2-methyl-, 2-methylpropyl ester
2-Propenoic acid, 2-methyl-, 2-methylpropyl ester
N-Butyl methacrylate
2-Propenoic acid, 2-methyl-, 1,2-ethanediyl ester
Aluminum, triethyl-
Borane, triethyl-
2-Ethyl-1-butanol
Nominated








































Yes























































Draft
PCCL3



Yes

Yes




Yes










Yes
Yes

Yes

Yes



Yes
Yes





Yes


Yes




Yes


Yes


Yes


Yes

Yes


































Yes




Final
PCCL3



Yes

Yes




Yes










Yes
Yes

Yes

Yes



Yes
Yes





Yes


Yes




Yes


Yes


Yes


Yes

Yes


































Yes




Draft
CCL 3





Yes


































Yes













Yes









































Public
Comment









Yes
Yes




















Yes








Yes























































Final
CCL 3





Yes


































Yes













Yes









































CCL 2


Yes







Yes





















































































CCL1


Yes







Yes





















































































        AS-10

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
97994
98000
98011
98033
98066
98077
98088
98099
98113
98135
98157
98168
98179
98191
98293
98464
98511
98522
98533
98544
98555
98566
98577
98599
98646
98668
98679
98737
98793
98828
98839
98851
98862
98873
98884
98920
98942
98953
98964
98986
99036
99047
99058
99069
99070
99081
99092
99116
99207
99309
99343
99354
99490
99503
99514
99525
99547
99558
99569
99570
99592
99616
99627
99638
99650
99718
99752
99763
99774
99821
99832
99854
99865
99876
99898
99912
99923
99934
99945
99967
99978
99990
100005
100016
100027
100061
100094
100107
100185
100209
100210
100254
100276
100298
100367
100378
Common Name
Tetrahydrofurfuiyl alcohol
Furfuiyl alcohol
Furfural
2-Thiophenecarboxaldehyde
tert-Butylbenzene
Benzotrichloride
Benzene, (trifluoromethyl)-
Benzenesulfonyl chloride
Benzenesulfonic acid
Trichlorophenylsilane
Benzene, 1-chloro-3-(trifluoromethyl)-
3-(Trifluoromethyl)benzenamine
Phenol, 3-(trifluoromethyl)-
Benzene, 1-(1 ,1-dimethylethyl)-3,5-dimethyl-
1 ,2-Benzenediol, 4-(1 ,1-dimethylethyl)-
Benzene, 1-nitro-3-(trifluoromethyl)-
Benzene, 1-(1 ,1-dimethylethyl)-4-methyl-
Cyclohexanol, 4-(1,1-dimethylethyl)-
4-tert-Butylcyclohexanone
p-tert-Butylphenol
. alpha. -Terpineol
Benzene, 1-chloro-4-(trifluoromethyl)-
Benzene, 1-chloro-4-(methylsulfonyl)-
p-Toluenesulfonyl chloride
Benzenesulfonamide, 4-chloro-
Benzenesulfonic acid, 4-chloro-
p-Phenolsulfonic acid
p-tert-Butylbenzoic acid
L-Proline, 5-oxo-
Cumene
alpha- Methylstyrene
alpha- Methylbenzenemethanol
Acetophenone
Benzal chloride
Benzoyl chloride
Nicotin amide
Cyclohexanamine, N,N-dimethyl-
Nitrobenzene
Pyrazinecarboxamide
Picolinic acid
Ethanone, 1-(3-aminophenyl)-
Benzoic acid, 3-methyl-
Benzoic acid, 3-amino-
Benzoic acid, 3-hydroxy-
Phenol, 3-(dimethylamino)-
m-Nitrotoluene
Benzenamine, 3-nitro-
Citrazinic acid
Trehalose
Dichloran
3,5-Dinitrobenzoic acid
1 ,3,5-Trinitrobenzene
Can/one
Benzole acid, 3,4-dihydroxy-
Benzene, 1 ,2-dimethyl-4-nitro-
Benzenamine, 2-methyl-4-nitro-
Benzene, 1,2-dichloro-4-nitro-
5-Nitro-o-toluidine
1,2-Benzenediamine, 4-nitro-
Phenol, 2-amino-4-nitro-
5-Nitro-o-anisidine
Benzaldehyde, 3-nitro-
1 ,3-Diisopropylbenzene
1 ,3-Benzenedicarbonyl dichloride
1 ,3-Dinitrobenzene
Phenol, 4-(1-methylpropyl)-
Benzoic acid, 4-methyl-, methyl ester
Benzole acid, 4-hydroxy-, methyl ester
Benzole acid, 4-nitro-, ethyl ester
Cyclohexane, 1-methyl-4-(1-methylethyl)-
1 ,3-Cyclohexadiene, 2-methyl-5-(1-methylethyl)-
1 ,4-Cyclohexadiene, 1-methyl-4-(1-methylethyl)-
alpha-Terpinene
p-Cymene
Phenol, 4-(1-methylethyl)-
Ethanone, 1-(4-chlorophenyl)-
Ethanone, 1-(4-aminophenyl)-
Ethanone, 1-(4-hydroxyphenyl)-
Benzoic acid, 4-methyl-
p-Hydroxybenzoic acid
Benzenamine, N,N,4-trimethyl-
p-Nitrotoluene
p-Chloronitrobenzene
p-Nitroaniline
p-Nitrophenol
Ethanone, 1-(4-methoxyphenyl)-
Benzoic acid, 4-methoxy-
Benzaldehyde, 4-(dimethylamino)-
Benzene, 1,4-bis(1-methylethyl)-
1 ,4-Benzenedicarbonyl dichloride
Terephthalic acid
p-Dinitrobenzene
4-Nitrobenzeneethanol
Benzene, 1-ethoxy-4-nitro-
1,2-Ethanediamine, N,N-diethyl-
Ethanol, 2-(diethylamino)-
Nominated
































































































Draft
PCCL3


Yes

Yes
Yes












Yes











Yes
Yes





Yes











Yes







Yes


Yes

Yes

Yes
















Yes
Yes







Yes
Yes




Final
PCCL3


Yes

Yes
Yes












Yes











Yes
Yes





Yes











Yes







Yes


Yes

Yes

Yes
















Yes
Yes







Yes
Yes




Draft
CCL 3





































Yes


























Yes































Public
Comment





























Yes


Yes




Yes



































Yes






















Final
CCL 3





































Yes


























Yes































CCL 2





































Yes



































Yes






















CCL1





































Yes



































Yes






















        AS-11

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
100390
100403
100436
100447
100469
100470
100505
100516
100527
100538
100549
100550
100607
100618
100630
100641
100663
100696
100709
100743
100754
100801
100845
100856
100867
100889
100970
100992
101020
101053
101100
101144
101202
101213
101257
101279
101371
101393
101417
101428
101439
101484
101508
101542
101553
101611
101633
101677
101688
101724
101735
101779
101804
101815
101837
101848
101860
101871
101906
101962
101973
102012
102067
102078
102089
102090
102136
102192
102205
102249
102272
102283
102363
102501
102545
102603
102692
102705
102716
102761
102772
102794
102829
102852
102965
103059
103093
103117
103162
103242
103264
103286
103297
103333
103344
103413
Common Name
Benzene, (bromomethyl)-
4-Vinylcyclohexene
4-Vinylpyridine
Benzyl chloride
Benzylamine
Benzonitrile
3-Cyclohexene-1-carboxaldehyde
Benzyl alcohol
Benzaldehyde
Benzenemethanethiol
3-Pyridinecarbonitrile
3-Pyridinemethanol
Cyclohexanamine, N-methyl-
N-Methylaniline
Hydrazine, phenyl-
(Hydroxyimino)cyclohexane
Anisole
2-Vinylpyridine
2-Pyridinecarbonitrile
Morpholine, 4-ethyl-
N-Nitrosopiperidine
Benzene, 1-ethenyl-3-methyl-
Benzene, 1-methoxy-3-methyl-
Benzyltrimethylammonium hydroxide
. alpha., .alpha.-Dimethylbenzeneethanol
Cyclamic acid
Hexamethylenetetramine
Aluminum, tris(2-methylpropyl)-
Triphenyl phosphite
Anilazine
Cloprop
4,4'-Methylenebis(2-chloroaniline)
Triclocarban
Chlorpropham
Dinitrosopentamethylenetetramine
Barban
1 ,3,5-Triazine, 2,4,6-tris(2-propenyloxy)-
2-Propenal, 2-methyl-3-phenyl-
Benzeneacetic acid, methyl ester
Fenuron
2-Propenoic acid, 2-methyl-, cyclohexyl ester
Benzene, (2,2-dimethoxyethyl)-
4-Amino-3,4'-disulfoazobenzene
4-Aminodiphenylamine
p-Bromophenyl phenyl ether
4,4'-Methylenebis(N,N-dimethyl)benzenamine
Benzene, 1,1'-oxybis[4-nitro-
Benzenamine, 4-octyl-N-(4-octylphenyl)-
4,4'-Methylenedi(phenyl isocyanate)
1 ,4-Benzenediamine, N-(1-methylethyl)-N'-phenyl-
Benzenamine, 4-(1-methylethoxy)-N-phenyl-
4,4'-Methylenedianiline
4,4'-Diaminodiphenyl ether
Benzene, 1,1'-methylenebis-
Dicyclohexylamine
Phenyl ether
. alpha. -Hexylcinnamaldehyde
1 ,4-Benzenediamine, N-cyclohexyl-N'-phenyl-
Diglycidyl resorcinol ether
1 ,4-Benzenediamine, N,N'-bis(1-methylpropyl)-
Benzeneacetic acid, ethyl ester
Butanamide, 3-oxo-N-phenyl-
Guanidine, N,N'-diphenyl-
Urea, N,N'-diphenyl-
Diphenylthiourea
Diphenyl carbonate
Benzeneacetic acid, 2-methylpropyl ester
Benzeneacetic acid, 3-methylbutyl ester
Benzeneacetic acid, 2-phenylethyl ester
Boroxin, trimethoxy-
Benzenamine, N-ethyl-3-methyl-
Acetamide, N-(S-aminophenyl)-
3,4-Dichlorophenyl isocyanate
Benzenamine, 4-methoxy-2-methyl-
Ferrocene
Edetol
1-Propanamine, N,N-dipropyl-
2-Propen-1-amine, N,N-di-2-propenyl-
Triethanolamine
1 ,2,3-Propanetriol, triacetate
Morpholine, 4-(2-benzothiazolylthio)-
Ethanol, 2,2'-(butylimino)bis-
1-Butanamine, N,N-dibutyl-
Phosphorous acid, tributyl ester
Benzene, (2-nitroethenyl)-
Benzenepropanol, . alpha.,. alpha.-dimethyl-
Acetic acid, 2-ethylhexyl ester
2-Ethylhexyl acrylate
Phenol, 4-(phenylmethoxy)-
Nonanedioic acid, bis(2-ethylhexyl) ester
2-Propenoic acid, 3-phenyl-, methyl ester
Propanoic acid, 2-methyl-, phenylmethyl ester
Benzene, 1,1'-(1,2-ethanediyl)bis-
Azobenzene
Morpholine, 4,4'-dithiobis-
2-Propenoic acid, 3-phenyl-, phenylmethyl ester
Nominated
































Yes































































Draft
PCCL3

Yes

Yes



Yes
Yes

Yes




Yes
Yes









Yes

Yes














Yes

Yes


Yes


Yes
Yes


Yes


Yes



















Yes








Yes








Final
PCCL3

Yes

Yes



Yes
Yes

Yes




Yes
Yes









Yes

Yes














Yes

Yes


Yes


Yes
Yes


Yes


Yes



















Yes








Yes








Draft
CCL 3



Yes















































Yes












































Public
Comment



Yes



Yes












Yes











Yes
Yes
Yes


























































Yes


Final
CCL 3



Yes















































Yes












































CCL 2
































































































CCL1
































































































        AS-12

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
103457
103480
103504
103548
103606
103639
103651
103695
103708
103719
103720
103742
103764
103822
103833
103844
103855
103902
103957
103968
104018
104121
104132
104154
104198
104201
104234
104381
104405
104450
104461
104472
104494
104518
104541
104552
104574
104610
104676
104687
104723
104745
104756
104767
104789
104825
104836
104870
104881
104905
104916
104938
104949
105055
105088
105113
105124
105135
105168
105306
105317
105340
105362
105373
105384
105395
105442
105453
105464
105522
105533
105544
105555
105566
105577
105588
105602
105646
105657
105679
105680
105748
105759
105760
105839
105873
105997
106116
106127
106149
106194
106207
106230
106241
106274
106309
Common Name
Acetic acid, 2-phenylethyl ester
Propanoic acid, 2-methyl-, 2-phenylethyl ester
Benzene, 1,1'-[oxybis(methylene)]bis-
Cinnamyl acetate
Propanoic acid, 2-methyl-, 2-phenoxyethyl ester
Benzene, (2-bromoethyl)-
n-Propylbenzene
Benzenamine, N-ethyl-
Formamide, N-phenyl-
Benzene, isocyanato-
Benzene, isothiocyanato-
2-Pyridineethanol
1-Piperazineethanol
Benzeneacetic acid
Benzenemethanamine, N,N-dimethyl-
Acetanilide
Phenylthiourea
Acetaminophen
Cyclamen aldehyde
1 ,4-Benzenediamine, N,N'-bis(1-methylheptyl)-
Benzeneacetic acid, 4-methoxy-
Benzene, 1-chloro-4-isocyanato-
Benzenamine, 4-butyl-
4-Methylbenzenesulfonic acid
1-Piperazineethanamine, N,N,4-trimethyl-
2-Butanone, 4-(4-methoxyphenyl)-
C.l. Food Yellow 6
Ethanol, 2,2'-[1 ,4-phenylenebis(oxy)]bis-
Phenol, 4-nonyl-
Benzene, 1-methoxy-4-propyl-
Anethole
Benzeneacetonitrile, 4-methoxy-
1 ,4-Phenylene diisocyanate
n-Butylbenzene
3-Phenyl-2-propen-1-ol
Cinnamaldehyde
Benzyl formate
Dihydro-5-pentyl-2(3H)-furanone
5-Heptyldihydro-2(3H)-furanone
Ethanol, 2-(2-phenoxyethoxy)-
Benzene, decyl-
Pyridinium, 1-dodecyl-, chloride
1-Hexanamine, 2-ethyl-
2-Ethylhexanol
N,N-Diethyltrimethylenediamine
4-Methylbenzyl chloride
Benzene, 1-chloro-4-(chloromethyl)-
Benzaldehyde, 4-methyl-
Benzaldehyde, 4-chloro-
5-Ethyl-2-methylpyridine
Phenol, 4-nitroso-
Benzene, 1-methoxy-4-methyl-
Benzenamine, 4-methoxy-
Benzene, 1,4-diethyl-
1 ,4-Cyclohexanedimethanol
1 ,4-Benzoquinone dioxime
Benzene, 1 ,4-dinitroso-
4-Methoxybenzenemethanol
N,N-Diethylaminoethyl methacrylate
2-Methyl-1-pentanol
1-Hexyn-3-ol
Acetic acid, cyano-, methyl ester
Acetic acid, bromo-, ethyl ester
Propanoic acid, ethyl ester
Propanoic acid, ethenyl ester
Ethyl chloroacetate
2-Pentanone, 4-methyl-, oxime
Methyl acetoacetate
sec-Butyl acetate
Bis(1 ,3-dimethylbutyl) maleate
Propanedioic acid, diethyl ester
Butanoic acid, ethyl ester
N.N'-Diethylthiourea
Ethyl cyanoacetate
Diethyl acetal
Carbonic acid, diethyl ester
Caprolactam
Peroxydicarbonic acid, bis(l-methylethyl) ester
Bis(isopropyl) thioperoxydicarbonate
2,4-Dimethylphenol
1-Butanol, 3-methyl-, propanoate
Peroxide, bis(l-oxododecyl)
2-Butenedioic acid (2E)-, dibutyl ester
2-Butenedioic acid (2Z)-, dibutyl ester
Bis(3-aminopropyl)methylamine
2,6-Octadien-1-ol, 3,7-dimethyl-, acetate, (2E)-
Dibutyl adipate
Octadecanoic acid, 2-(2-hydroxyethoxy)ethyl ester
Diethylene glycol monooleate
Octadecanoic acid, 12-hydroxy-
Hexanedioic acid, dipropyl ester
1-Hexanamine,2-ethyl-N-(2-ethylhexyl)-
6-Octenal, 3,7-dimethyl-
trans-Geraniol

Ethyl heptanoate
Nominated
































































































Draft
PCCL3






Yes




























Yes







Yes










Yes
Yes
















Yes



Yes


Yes
















Final
PCCL3






Yes










Yes

















Yes







Yes










Yes
Yes
















Yes



Yes


Yes
















Draft
CCL 3






Yes

























































































Public
Comment






Yes










Yes















Yes













































Yes
















Final
CCL 3






Yes

























































































CCL 2
































































































CCL1
































































































        AS-13

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
106310
106354
106365
106376
106387
106412
106434
106445
106478
106489
106490
106503
106514
106581
106638
106650
106683
106694
106707
106718
106729
106741
106752
106876
106887
106912
106923
106945
106956
106978
106989
106990
107017
107028
107039
107040
107051
107073
107108
107119
107120
107131
107142
107153
107164
107186
107197
107200
107211
107222
107255
107299
107302
107313
107357
107379
107391
107404
107415
107459
107460
107562
107584
107642
107664
107700
107711
107722
107835
107879
107880
107891
107915
107926
107948
107960
107982
108010
108032
108054
108098
108101
108112
108167
108189
108190
108203
108214
108225
108236
108247
108269
108292
108305
108316
108327
Common Name
Butyric anhydride
3-Heptanone
Propyl propionate
Benzene, 1,4-dibromo-
Benzene, 1-bromo-4-methyl-
Phenol, 4-bromo-
p-Chlorotoluene
p-Cresol
p-Chloroaniline
p-Chlorophenol
p-Toluidine
p-Phenylenediamine
Quinone
Piperazine, 1 ,4-dimethyl-
2-Propenoic acid, 2-methylpropyl ester
Butanedioic acid, dimethyl ester
3-Octanone
1,2,6-Hexanetriol
Hexanoic acid, methyl ester
2-Propenoic acid, 2-cyanoethyl ester
5-Heptenal, 2,6-dimethyl-
2-Propenoic acid, 2-ethoxyethyl ester
Carbonochloridic acid, oxydi-2,1-ethanediyl ester
1 ,2-Epoxy-4-(epoxyethyl)cyclohexane
1 ,2-Butylene oxide
2-Propenoic acid, 2-methyl-, oxiranylmethyl ester
Oxirane, [(2-propenyloxy)methyl]-
Propane, 1-bromo-
1-Propene, 3-bromo-
Butane
1-Butene
1 ,3-Butadiene
2-Butene
Acrolein
1-Propanethiol
1-Bromo-2-chloroethane
Ally! chloride
2-Chloroethanol
Propylamine
Allylamine
Propanenitrile
Acrylonitrile
Acetonitrile, chloro-
Ethylenediamine
Formaldehyde cyanohydrin
2-Propen-1-ol
Propargyl alcohol
Chloroacetaldehyde
Ethylene glycol
Glyoxal
Vinyl methyl ether
Acetaldehyde, oxime
Chloromethyl methyl ether
Methyl formate
Ethanesulfonic acid, 2-amino-
Silane, trichloro-2-propenyl-
Diisobutylene
2-Pentene, 2,4,4-trimethyl-
Hexylene glycol
2-Pentanamine, 2,4,4-trimethyl-
Disiloxane, hexamethyl-
O,O-Diisopropyl dithiophosphate
2-Propenamide, N-(1 ,1-dimethylethyl)-
Dimethyl dioctadecyl ammonium chloride
Phosphoric acid, dibutyl ester
2-Pentanone, 4-methoxy-4-methyl-
Ethaneperoxoic acid, 1,1-dimethylethyl ester
Silane, trichloropentyl-
Pentane, 2-methyl-
2-Pentanone
1 ,3-Butylene glycol
Acetaldol
Acetamide, 2-cyano-
Butyric acid
Propanoic acid, 3-chloro-
Propanoic acid, 3-mercapto-
Propylene glycol 1-methyl ether
N,N-Dimethylethanolamine
Propane, 1-nitro-
Vinyl acetate
2-Pentanamine, 4-methyl-
Methyl isobutyl ketone
4-Methyl-2-pentanol
Dimepranol
2-Propanamine, N-(l-methylethyl)-
Imidodicarbonic diamide
Isopropyl ether
Isopropyl acetate
1-Propen-2-ol, acetate
Isopropyl chloroformate
Acetic anhydride
3H-Pyrazol-3-one, 2,4-dihydro-5-methyl-
2(3H)-Furanone, dihydro-5-methyl-
2,5-Furandione, dihydro-
Maleic anhydride
1 ,3-Dioxolan-2-one, 4-methyl-
Nominated















































Yes






































Yes









Draft
PCCL3
Yes





Yes
















Yes







Yes

Yes






Yes
Yes

Yes

Yes
Yes

Yes
Yes


Yes




















Yes


Yes
Yes

Yes


Yes







Yes



Yes

Final
PCCL3
Yes





Yes
















Yes







Yes

Yes






Yes
Yes

Yes

Yes
Yes
Yes
Yes
Yes


Yes




















Yes


Yes
Yes

Yes


Yes







Yes



Yes

Draft
CCL 3































Yes

Yes











Yes


Yes















































Public
Comment







Yes























Yes

Yes








Yes




Yes
Yes
Yes























Yes







Yes




Yes









Final
CCL 3































Yes

Yes











Yes


Yes















































CCL 2
































































































CCL1
































































































        AS-14

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
108361
108394
108429
108430
108441
108452
108463
108474
108485
108554
108598
108601
108623
108645
108656
108678
108689
108690
108703
108714
108736
108747
108758
108770
108781
108805
108827
108838
108849
108861
108872
108894
108918
108930
108941
108952
108985
108996
109002
109013
109024
109046
109057
109068
109091
109160
109171
109193
109217
109319
109433
109466
109524
109535
109557
109580
109591
109604
109615
109637
109659
109660
109671
109693
109706
109739
109740
109762
109773
109784
109795
109831
109853
109864
109875
109897
109922
109944
109955
109977
109999
110009
110010
110021
110032
110054
110123
110156
110167
110178
110189
110190
110214
110225
110258
110269
Common Name
Benzene, 1,3-dibromo-
m-Cresol
m-Chloroaniline
Phenol, 3-chloro-
Benzenamine, 3-methyl-
1 ,3-Phenylenediamine
Resorcinol
2,4-Dimethylpyridine
2,6-Dimethylpyridine
Glutaric anhydride
Propanedioic acid, dimethyl ester
Bis(2-chloro-1-methylethyl) ether
Metaldehyde
Butanoic acid, 3-methyl-, ethyl ester
Propylene glycol monomethyl ether acetate
1 ,3,5-Trimethylbenzene
Phenol, 3,5-dimethyl-
Benzenamine, 3,5-dimethyl-
1 ,3,5-Trichlorobenzene
1 ,3-Benzenediamine, 5-methyl-
1,3,5-Benzenetriol
1 ,3,5-Triazine, hexahydro-1 ,3,5-trimethyl-
2,4,6-Trimethylpyridine
Cyanuric chloride
Melamine
Cyanuric acid
4-Heptanol, 2,6-dimethyl-
Diisobutyl ketone
4-Methyl-2-pentanol, acetate
Bromobenzene
Methyl cyclohexane
4-Methylpyridine
Cyclohexylamine
Cyclohexanol
Cyclohexanone
Phenol
Thiophenol
3-Methylpyridine
3-Pyridinol
Piperazine, 1-methyl-
Morpholine, 4-methyl-
Pyridine, 2-bromo-
Piperidine, 2-methyl-
2-Methylpyridine
2-Chloropyridine
Triethylene glycol dimethacrylate
Tetraethyleneglycol dimethacrylate
Butyl isovalerate
Butanoic acid, butyl ester
Nonanedioic acid, dihexyl ester
Dibutyl sebacate
Thiourea, N,N'-dibutyl-
Pentanoic acid
Propane, 1-(ethenyloxy)-2-methyl-
1 ,3-Propanediamine, N,N-dimethyl-
(2-Aminoethyl)carbamic acid
Ethanol, 2-(1-methylethoxy)-
Acetic acid, propyl ester
Propyl chloroformate
Boron, trifluoro[1,1'-oxybis[ethane]]-, (T-4)-
Butane, 1-bromo-
Pentane
1-Pentene
Butane, 1-chloro-
Propane, 1-bromo-3-chloro-
Butylamine
Butanenitrile
1 ,3-Propanediamine
Malononitrile
Propanenitrile, 3-hydroxy-
Butyl mercaptan
N-Methylethanolamine
Ethanamine, 2-methoxy-
2-Methoxyethanol
Methane, dimethoxy-
Diethylamine
Vinyl ethyl ether
Ethyl formate
Ethyl nitrite
1 H-Pyrrole
Tetrahydrofuran
Furan
Thiophene, tetrahydro-
Thiophene
2,5-Hexanediol, 2,5-dimethyl-
Peroxide, bis(1,1-dimethylethyl)
2-Hexanone, 5-methyl-
Succinic acid
Maleic acid
Fumaric acid
Tetramethylethylenediamine
Isobutyl acetate
1 ,2-Hydrazinedicarboxamide
Peroxide, diacetyl
Glycine, N-methyl-N-[(9Z)-1-oxo-9-octadecenyl]-
2-Propenamide, N,N'-methylenebis-
Nominated
































































































Draft
PCCL3

Yes









Yes


Yes








Yes
Yes
Yes



Yes


Yes
Yes
Yes

Yes
Yes





Yes






















Yes

Yes




Yes






Yes
Yes









Yes




Final
PCCL3

Yes









Yes


Yes








Yes
Yes
Yes



Yes


Yes
Yes
Yes

Yes
Yes





Yes






















Yes

Yes




Yes






Yes
Yes









Yes




Draft
CCL 3









































































Yes






















Public
Comment















Yes



















Yes




























































Final
CCL 3









































































Yes






















CCL 2





























Yes


































































CCL1





























Yes


































































        AS-15

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
110270
110292
110305
110338
110361
110418
110429
110430
110441
110496
110510
110521
110543
110576
110587
110598
110601
110623
110634
110645
110656
110678
110690
110714
110747
110758
110781
110805
110816
110827
110838
110850
110861
110883
110894
110918
110930
110941
110952
110963
110974
110985
111115
111137
111148
111159
111160
111171
111182
111193
111206
111217
111228
111251
111262
111273
111308
111319
111342
111364
111400
111411
111422
111433
111444
111466
111499
111557
111579
111604
111659
111660
111693
111706
111717
111762
111773
111784
111820
111842
111853
111875
111886
111900
111911
111922
111944
111966
111977
112005
112027
112038
112050
112072
112129
112152
Common Name
Isopropyl myristate
Decyl octyl adipate
Octadecanamide, N,N'-1 ,2-ethanediylbis-
Dihexyl adipate
Tetradecanoic acid, butyl ester
Undecanal, 2-methyl-
Decanoic acid, methyl ester
2-Heptanone
Sorbic acid
Ethylene glycol monomethyl ether acetate
Pyridine borane
Butane, 1 ,4-dibromo-
Hexane
trans-1 ,4-Dichloro-2-butene
Amylamine
Pentanenitrile
1,4-Butanediamine
Pentanal
1 ,4-Butanediol
2-Butene-1,4-diol
1,4-Butynediol
Propanenitrile, 3-methoxy-
Butanal, oxime
Ethylene glycol dimethyl ether
Propyl formate
2-Chloroethyl vinyl ether
Propane, 1-isocyanato-
2-Ethoxyethanol
Disulfide, diethyl
Cyclohexane
Cyclohexene
Piperazine
Pyridine
1 ,3,5-Trioxane
Piperidine
Morpholine
6-Methyl-5-hepten-2-one
Pentanedioic acid
1 ,3-Propanediamine, N,N,N',N'-tetramethyl-
1-Propanamine, 2-methyl-N-(2-methylpropyl)-
2-Propanol, 1,1'-iminobis-
2-Propanol, 1,1'-oxybis-
Octanoic acid, methyl ester
2-Octanone
Heptanoic acid
Ethylene glycol monoethyl ether acetate
Heptanedioic acid
Propanoic acid, 3,3'-thiobis-
1 ,6-Hexanediamine, N,N,N',N'-tetramethyl-
Decanedioyl dichloride
Decanedioic acid
Ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-, diacetate
Triethylene glycol dinitrate
Hexane, 1-bromo-
1-Hexanamine
1-Hexanol
Glutaraldehyde
1-Hexanethiol
Butyl vinyl ether
Butyl isocyanate
Diethylenetriamine
N-Hydroxyethylethylenediamine
Diethanolamine
Propane, 1,1'-oxybis-
Bis(2-chloroethyl) ether
Diethylene glycol
Hexahydroazepine
Ethylene glycol diacetate
Octadecanamide, N-(2-hydroxyethyl)-
Octadecanoic acid, 2-hydroxyethyl ester
Octane
1-Octene
Adiponitrile
1-Heptanol
Heptanal
Ethylene glycol monobutyl ether
Diethylene glycol monomethyl ether
1 ,5-Cyclooctadiene
Dodecanoic acid, methyl ester
Nonane
Octane, 1-chloro-
1-Octanol
1-Octanethiol
Diethylene glycol monoethyl ether
Bis(2-chloroethoxy)methane
1-Butanamine, N-butyl-
3,3'-lminobispropanenitrile
Diethylene glycol dimethyl ether
Propanenitrile, 3,3'-thiobis-
Dodecyl trimethyl ammonium chloride
Cetyl trimethyl ammonium chloride
1-Octadecanaminium, N,N,N-trimethyl-, chloride
Nonanoic acid
Ethylene glycol monobutyl ether acetate
Methyl nonyl ketone
Diethylene glycol monoethyl ether acetate
Nominated
































































































Draft
PCCL3












Yes




Yes
Yes

Yes








Yes


Yes

Yes





















Yes



Yes

Yes

Yes
Yes
Yes





Yes
Yes

Yes




















Final
PCCL3












Yes




Yes
Yes

Yes








Yes


Yes

Yes





















Yes



Yes

Yes

Yes
Yes
Yes





Yes
Yes

Yes




















Draft
CCL 3












Yes



















































































Public
Comment












Yes




Yes














































































Final
CCL 3












Yes



















































































CCL 2
































































































CCL1
































































































        AS-16

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
112163
112185
112243
112254
112265
112276
112298
112301
112312
112345
112356
112367
112378
112389
112390
112403
112414
112425
112447
112458
112492
112505
112538
112549
112550
112572
112594
112607
112618
112629
112630
112674
112696
112709
112721
112732
112754
112765
112801
112845
112856
112867
112903
112914
112925
112969
113484
113928
113984
114078
114261
114830
115071
115106
115117
115173
115195
115219
115253
115275
115286
115297
115322
115695
115719
115775
115822
115833
115844
115866
115902
115957
115968
115980
116029
116096
116110
116143
116154
116165
116176
116290
116370
116530
116665
116712
116756
117088
117102
117124
117180
117395
117613
117624
117793
117806
Common Name
Dodecanoyl chloride
Dimethyl laurylamine
1 ,2-Ethanediamine, N,N'-bis(2-aminoethyl)-
Ethylene glycol monohexyl ether
Ethane, 1,2-bis(2-chloroethoxy)-
Triethylene glycol
Decane, 1-bromo-
1-Decanol
Decanal
Diethylene glycol monobutyl ether
Triethylene glycol monomethyl ether
Diethylene glycol diethyl ether
Undecanoic acid
10-Undecenoic acid
Hexadecanoic acid, methyl ester
Dodecane
1-Dodecene
1-Undecanol
Undecanal
10-Undecenal
Triethylene glycol dimethyl ether
Triethylene glycol monoethyl ether
1-Dodecanol
Dodecanal
1-Dodecanethiol
Tetraethylenepentamine
Diethylene glycol monohexyl ether
Ethanol,2,2'-[oxybis(2,1-ethanediyloxy)]bis-
Octadecanoic acid, methyl ester
9-Octadecenoic acid (9Z)-, methyl ester
9,12-Octadecadienoic acid (9Z,12Z)-, methyl ester
Hexadecanoyl chloride
Dimethylcetylamine
1-Tridecanol
1-Tetradecanol
Butane, 1 ,1'-[oxybis(2,1-ethanediyloxy)]bis-
1-Tetradecanamine, N,N-dimethyl-
Octadecanoyl chloride
Oleic acid
13-Docosenamide, (13Z)-
Docosanoic acid
13-Docosenoicacid,(13Z)-
9-Octadecen-1-amine, (9Z)-
9-Octadecenenitrile, (9Z)-
1-Octadecanol
Octadecane, 1-isocyanato-
N-2-Ethylhexylbicycloheptenedicarboximide
Chlorpheniramine maleate
Penicillin G Potassium
ERYTHROMYCIN
Propoxur
Acetic acid, 2-phenylhydrazide
Propylene
Dimethyl ether
Isobutene
Acetaldehyde, tribromo-
3-Butyn-2-ol, 2-methyl-
Trichloroethylsilane
Cyclobutane, octafluoro-
Chlorendic anhydride
Chlorendic acid
Endosulfan
Dicofol
1 ,3-Propanediol, 2-amino-2-methyl-
alpha-Santalol
Pentaerythritol
Silicic acid (H4SIO4), tetrakis(2-ethylhexyl) ester
Pentaerythrityl tetrastearate
2-Butyl-2-ethyl-1 ,3-propanediol
Triphenyl phosphate
Fensulfothion
1 ,6-Octadien-3-ol, 3,7-dimethyl-, acetate
Tris(chloroethyl)phosphate
Phosphonic acid, ethenyl-, bis(2-chloroethyl) ester
Cyclohexanol, 3,3,5-trimethyl-
2-Propanone, 1-hydroxy-
1-Propene, 2-methoxy-
Tetrafluoroethene
1-Propene, 1,1, 2,3,3, 3-hexafluoro-
Hexachloroacetone
Phosphorous acid, tris(l-methylethyl) ester
Tetradifon
Bisphenol A bis(2-hydroxypropyl) ether
Butanoic acid, 2-methyl-
Moskene
Violanthrone
C.I. Solvent Blue 104
Tetrachlorophthalic anhydride
9,10-Anthracenedione, 1,8-dihydroxy-
9,10-Anthracenedione, 1,5-dihydroxy-
Tecnazene
Quercetin
[1,1'-Biphenyl]-2,2'-disulfonic acid, 4,4'-diamino-
1 ,5-Naphthalenedisulfonic acid, 2-amino-
2-Aminoanthraquinone
Dichlone
Nominated

















































Yes
Yes










Yes
Yes

































Draft
PCCL3

Yes



Yes

Yes

Yes












Yes































Yes





Yes
Yes
Yes


Yes






Yes




Yes


















Final
PCCL3

Yes



Yes

Yes

Yes












Yes


























Yes




Yes





Yes
Yes
Yes


Yes






Yes




Yes


















Draft
CCL 3
































































































Public
Comment









Yes







































Yes





Yes





Yes
Yes









Yes






Yes
















Final
CCL 3

















































Yes














































CCL 2
































































































CCL1
































































































        AS-17

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
117828
117839
117840
118036
118127
118332
118478
118489
118525
118558
118581
118605
118616
118694
118752
118796
118821
118901
118912
118923
118934
118967
119062
119073
119277
119324
119335
119346
119368
119391
119471
119517
119539
119584
119619
119642
119653
119722
119799
119802
119846
119904
119937
120116
120127
120149
120183
120218
120321
120354
120365
120401
120467
120478
120514
120547
120558
120569
120570
120581
120616
120627
120718
120729
120785
120809
120832
120923
120934
120956
121006
121039
121142
121175
121197
121211
121324
121335
121346
121391
121437
121448
121459
121471
121540
121573
121608
121664
121697
121722
121733
121755
121799
121824
121868
121879
Common Name
Bis(2-methoxyethyl) phthalate
Bis(2-butoxyethyl) phthalate
Di-n-octyl phthalate
1 ,3,6-Naphthalenetrisulfonic acid, 7-amino-
1 H-lndole, 2,3-dihydro-1 ,3,3-trimethyl-2-methylene-
1 ,3-Naphthalenedisulfonic acid, 6-amino-
Pyrazolone T
Isatoic anhydride
1,3-Dichloro-5,5-dimethylhydantoin
Benzole acid, 2-hydroxy-, phenyl ester
Benzole acid, 2-hydroxy-, phenylmethyl ester
2-Ethylhexyl salicylate
Benzole acid, 2-hydroxy-, ethyl ester
Benzene, 1 ,3-dichloro-2-methyl-
Chloranil
2,4,6-Tribromophenol
4,4'-Methylenebis(2,6-di-t-butylphenol)
Benzole acid, 2-methyl-
o-Chlorobenzoic acid
Anthranilic acid
Ethanone, 1-(2-hydroxyphenyl)-
Trinitrotoluene
Ditridecyl phthalate
Octyl decyl phthalate
2,4-Dinitroanisole
Benzenamine, 4-methyl-3-nitro-
2-Nitro-p-cresol
Phenol, 4-amino-2-nitro-
Methyl salicylate
1(2H)-Phthalazinone
2,2'-Methylenebis(6-tert-butyl-p-cresol)
1 ,2-Propanedione, 1-phenyl-, 2-oxime
Benzoin
4,4'-Bis(dimethylamino)benzhydrol
Benzophenone
1 ,2,3,4-Tetrahydronaphthalene
Isoquinoline
4-Amino-4'-nitro-2,2'-stilbenedisulfonic acid
2-Naphthalenesulfonic acid, 5-amino-
Benzoic acid, 2,2'-dithiobis-
2H-1-Benzopyran-2-one, 3,4-dihydro-
3,3'-Dimethoxybenzidine
3,3'-Dimethylbenzidine
Isoeugenol benzyl ether
Anthracene
Benzaldehyde, 3,4-dimethoxy-
2-Naphthalenesulfonic acid
Benzaldehyde, 4-(diethylamino)-
o-Benzyl-p-chlorophenol
Benzamide, 3-amino-4-methoxy-N-phenyl-
Dichlorprop
Laurie diethanolamide
Dibenzoylmethane
Benzoic acid, 4-hydroxy-, ethyl ester
Benzyl benzoate
Dipentamethylenethiuram tetrasulfide
Diethylene glycol dibenzoate
Benzoflex T 150
1,3-Benzodioxole-5-carboxaldehyde
Isosafrole
Dimethyl terephthalate
Piperonyl sulfoxide
p-Cresidine
Indole
2,2'-Dithiobisbenzothiazole
Catechol
2,4-Dichlorophenol
Cyclopentanone
2-lmidazolidinone
Phenol, 2,4-bis(1,1-dimethylpropyl)-
Phenol, 2-(1,1-dimethylethyl)-4-methoxy-
Benzenesulfonic acid, 2-methyl-5-nitro-
2,4-Dinitrotoluene
Benzene, 1-chloro-2-nitro-4-(trifluoromethyl)-
Arsonic acid, ( 4-hydroxy- 3-nitrophenyl)-
Pyrethrin I
Benzaldehyde, 3-ethoxy-4-hydroxy-
Vanillin
Benzoic acid, 4-hydroxy-3-methoxy-
Oxiranecarboxylic acid, 3-phenyl-, ethyl ester
Boric acid (H3BO3), trimethyl ester
Triethylamine
Phosphorous acid, trimethyl ester
Metanilic acid
Benzethonium chloride
Sulfanilic acid
Benzenesulfonyl chloride, 4-(acetylamino)-
2-Thiazolamine, 5-nitro-
N,N-Dimethylaniline
Benzenamine, N,N,3-trimethyl-
Benzene, 1-chloro-3-nitro-
Malathion
Benzoic acid, 3,4,5-trihydroxy-, propyl ester
RDX (Hexahydro-1 ,3,5-trinitro-1 ,3,5-triazine)
Benzene, 2-chloro-1 -methyl-4-nitro-
Benzenamine, 2-chloro-4-nitro-
Nominated



























































































Yes




Draft
PCCL3





















Yes













Yes
























Yes

Yes


Yes






Yes








Yes









Yes

Yes


Final
PCCL3





















Yes













Yes
























Yes

Yes


Yes






Yes








Yes









Yes

Yes


Draft
CCL 3

















































































Yes











Yes


Public
Comment


Yes

























Yes





Yes

Yes













Yes















Yes










Yes


















Final
CCL 3

















































































Yes











Yes


CCL 2


































































Yes





Yes




















Yes


CCL1


































































Yes





Yes




















Yes


        AS-18

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
121880
121904
121915
121926
122009
122010
122043
122076
122112
122145
122189
122190
122203
122327
122372
122394
122407
122429
122485
122521
122576
122598
122601
122623
122634
122667
122689
122703
122758
122781
122792
122805
122827
122883
122963
122974
122996
123002
123013
123024
123035
123057
123079
123091
123115
123159
123171
123193
123239
123251
123284
123308
123319
123331
123342
123353
123386
123397
123411
123422
123488
123513
123546
123568
123626
123637
123682
123728
123739
123751
123762
123773
123795
123819
123864
123911
123922
123955
123966
123999
124027
124038
124049
124050
124072
124094
124107
124130
124163
124174
124185
124196
124221
124254
124265
124287
Common Name
Phenol, 2-amino-5-nitro-
Benzoyl chloride, 3-nitro-
Isophthalic acid
m-Nitrobenzoic acid
Ethanone, 1-(4-methylphenyl)-
Benzoyl chloride, 4-chloro-
Benzoyl chloride, 4-nitro-
Ethanamine, 2,2-dimethoxy-N-methyl-
sulfadimethoxine
Fenitrothion
Benzyl hexadecyl dimethyl ammonium chloride
Dimethyl octadecyl benzyl ammonium chloride
Triisopropanolamine
9-Octadecenoic acid (9Z)-, 1,2,3-propanetriyl ester
Phenol, 4-(phenylamino)-
Diphenylamine
Heptanal, 2-(phenylmethylene)-
Propham
Zingerone
Phosphorous acid, triethyl ester
3-Buten-2-one, 4-phenyl-
Phenoxyacetic acid
Oxirane, (phenoxymethyl)-
Decanedioic acid, bis(2-ethylhexyl) ester
Propanoic acid, phenylmethyl ester
1 ,2-Diphenylhydrazine
2-Propenoic acid, 3-phenyl-, 3-phenylpropyl ester
2-Phenylethyl propionate
Benzathine diacetate
Benzeneacetaldehyde
Acetic acid, phenyl ester
Acetamide, N-(4-aminophenyl)-
Butanamide, N-(4-ethoxyphenyl)-3-oxo-
4-Chlorophenoxyacetic acid
1 ,4-Piperazinediethanol
Benzenepropanol
Ethylene glycol monophenyl ether
4-Morpholinepropanamine
Dodecylbenzene
Benzene, tridecyl-
Cetylpyridinium chloride
2-Ethylhexanal
Phenol, 4-ethyl-
Benzene, 1-chloro-4-(methylthio)-
Benzaldehyde, 4-methoxy-
Pentanal, 2-methyl-
4-Nonanol, 2,6,8-trimethyl-
4-Heptanone
Succinoyl peroxide
Butanedioic acid, diethyl ester
Propanoic acid, 3,3'-thiobis-, didodecyl ester
p-Aminophenol
Hydroquinone
Maleic hydrazide
1 ,2-Propanediol, 3-(2-propenyloxy)-
Myrcene
Propionaldehyde
Formamide, N-methyl-
Sincaline
4-Hydroxy-4-methyl-2-pentanone
3-Heptene, 2,2,4,6,6-pentamethyl-
3-Methyl-1-butanol
Acetylacetone
2,5-Pyrrolidinedione
Propionic anhydride
Paraldehyde
Hexanoic acid, 2-propenyl ester
Butyraldehyde
trans-Grot on aldehyde
Pyrrolidine
Pentanoic acid, 4-oxo-
Diazenedicarboxamide
Dioctyl adipate
Acetic acid, mercapto-, 1 ,2-ethanediyl ester
n-Butyl acetate
1 ,4-Dioxane
Isoamyl acetate
Octadecanoic acid, butyl ester
2-Octanol
Nonanedioic acid
2-Propen-1-amine, N-2-propenyl-
Cetyl dimethyl ethyl ammonium bromide
Adipic acid
Carbonochloridic acid, 1,2-ethanediyl ester
Octanoic acid
Hexamethylenediamine
Tetradecanoic acid, methyl ester
Octanal
2-Propanol, 1-(2-butoxyethoxy)-
Diethylene glycol monobutyl ether acetate
Decane
Nonanal
1-Dodecanamine
Tetradecanal
Octadecanamide
N,N- Dimethyl octadecylamine
Nominated








Yes


































































Yes




















Draft
PCCL3


Yes












Yes









Yes















Yes










Yes
Yes


Yes


Yes














Yes
Yes






Yes


Yes










Final
PCCL3


Yes












Yes









Yes















Yes










Yes
Yes


Yes


Yes














Yes
Yes






Yes


Yes










Draft
CCL 3











































































Yes




















Public
Comment


Yes





Yes



























Yes



















Yes










Yes







Yes






Yes







Yes





Final
CCL 3











































































Yes




















CCL 2

























Yes






































































CCL1

























Yes






































































        AS-19

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
124301
124389
124403
124414
124630
124641
124652
124685
124709
124732
124765
125122
125337
126067
126114
126136
126147
126158
126307
126330
126589
126716
126727
126738
126830
126863
126921
126965
126987
126998
127004
127060
127071
127082
127093
127173
127195
127208
127275
127311
127413
127479
127582
127639
127651
127684
127695
127797
127822
127913
128030
128041
128096
128370
128392
128427
128449
128585
128665
128803
128950
128972
129000
129066
129099
129157
129431
129646
129737
129793
130132
130143
130154
130176
130201
130370
131088
131099
131113
131157
131179
131180
131271
131522
131533
131544
131555
131566
131577
131704
131895
131920
132274
132296
132321
132434
Common Name

Carbon dioxide
Dimethylamine
Sodium methoxide
Methanesulfonyl chloride
Phosphonium, tetrakis(hydroxymethyl)-, chloride
Sodium cacodylate
2-Amino-2-methyl-1 -propanol
Silane, dichloroethenylmethyl-
1,2-Dibromo-1,1,2,2-tetrafluoroethane
Isoborneol
Isobornyl acetate
Primidone
3-Bromo-1-chloro-5,5-dimethylhydantoin
2-(Hydroxymethyl)-2-nitro-1,3-propanediol
Sucrose acetate isobutyrate
Sucrose octaacetate
2,3:4,5-Bis(2-butylene)tetrahydro-2-furaldehyde
Neopentyl glycol
Sulfolane
Dipentaerythritol
Phosphoric acid, tris(2-methylpropyl) ester
Tris(2,3-dibromopropyl) phosphate
Phosphoric acid tributyl ester
Sodium epichlorohydrinsulfonate
5-Decyne-4,7-diol, 2,4,7, 9-tetramethyl-
Sodium Ethasulfate
Sodium diacetate
Methacrylonitrile
Chloroprene
1-Chloro-2-propanol
2-Propanone oxime
Urea, hydroxy-
Acetic acid, potassium salt
Sodium acetate
Propanoic acid, 2-oxo-
N,N-Dimethylacetamide
Dalapon-sodium
Pimaric acid
Hydrocortisone-9.alpha.-fluoro
. alpha. -lonone
Retinol, acetate
Sulfapyridine monosodium salt
Diphenylsulfone
Chloramine T
Sodium 3-nitrobenzenesulfonate
Sulfisoxazole
Sulfamerazine
Zinc phenolsulfonate
.beta. -Pin ene
Potassium dimethyldithiocarbamate
Sodium dimethyldithiocarbamate
N-Chlorosuccinimide
2,6-Di-tert-butyl-p-cresol
Phenol, 2,6-bis(1 ,1-dimethylethyl)-
4,4'-Dinitro-2,2'-stilbenedisulfonic acid
Saccharin sodium
Violanthrone, 16,17-dimethoxy-
C. I. Vat Yellow 4
1 ,4-Di(4'-toluidino)anthraquinone
1 ,4-Diaminoanthraquinone
1 ,4,5,8-Naphthalenetetracarboxylic acid
Pyrene
Sodium warfarin
C.I. Vat Yellow 2
9,10-Anthracenedione, 2-methyl-1-nitro-
9,10-Anthracenedione, 1-hydroxy-
Carbic anhydride
Leucomalachite green
9H-Fluoren-9-one, 2,4,7-trinitro-
4-Amino-1-naphthalenesulfonic acid sodium salt
Sodium 1-naphthalenesulfonate
1,4-Naphthoquinone
Dehydrothio-p-toluidinesulfonic acid
C.I. Vat Blue 6
Vitamin K3 sodium bisulfite
Anthraquinone-2-sulfonate sodium salt
9,10-Anthracenedione, 2-chloro-
Dimethyl phthalate
Dicapryl phthalate
Diallyl phthalate
Dipentyl phthalate
1 ,5-Naphthalenedisulfonic acid, 3-amino-
Sodium pentachlorophenate
Dioxybenzone
Methanone, bis(2-hydroxy-4-methoxyphenyl)-
Methanone, bis(2,4-dihydroxyphenyl)-
Methanone, (2,4-dihydroxyphenyl)phenyl-
2-Hydroxy-4-methoxybenzophenone
Monobutyl phthalate
Dinex
C.I. Vat Brown 3
Sodium o-phenylphenoxide
2-Biphenylyl diphenyl phosphate
9H-Carbazol-3-amine, 9-ethyl-
Sodium N-cyclohexyl-N-palmitoyltaurate
Nominated















































Yes














Yes

































Draft
PCCL3


Yes















Yes



Yes





Yes
Yes

Yes




Yes














Yes












































Final
PCCL3


Yes















Yes



Yes





Yes
Yes

Yes




Yes














Yes












































Draft
CCL 3
































































































Public
Comment












Yes








































Yes
























Yes









Yes







Final
CCL 3
































































































CCL 2
































































































CCL1
































































































        AS-20

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
132649
132650
132661
132672
132683
132989
133062
133073
133142
133493
133595
133664
133904
134032
134203
134292
134327
134509
134623
134725
134816
134849
134850
135024
135193
135206
135239
135513
135579
135886
135988
136232
136301
136356
136367
136403
136458
136527
136538
136607
136776
136856
136958
136992
137031
137053
137064
137075
137097
137177
137199
137202
137268
137291
137304
137326
137406
137417
137428
137666
137995
138158
138227
138249
138250
138863
138932
139026
139059
139071
139082
139139
139333
139402
139457
139606
139651
139662
139888
139899
139946
140012
140034
140089
140103
140114
140294
140318
140498
140534
140567
140578
140603
140669
140670
140885
Common Name
Dibenzofuran
Dibenzothiophene
Naptalam
Naptalam-sodium
3-Hydroxy-N-1-naphthyl-2-naphthamide
Penicillin V Potassium
Captan
Folpet
Peroxide, bis(2,4-dichlorobenzoyl)
Benzenethiol, pentachloro-
Benzenesulfonyl chloride, 2-methyl-
C.l. Fluorescent Brightener9
Chloramben
Sodium Ascorbate
4-Chlorobenzophenone
Benzenamine, 2-methoxy-, hydrochloride
1-Naphthalenamine
9-Aminoacridine hydrochloride
N,N-Diethyl-m-toluamide (DEET)
Ephedrine sulfate
Benzil
Methanone, (4-methylphenyl)phenyl-
4-Chlorobenzophenone
Benzaldehyde, 2-methoxy-
2-Naphthalenol
Cupferron
Methapyrilene hydrochloride
Ferricon
Benzamide, N,N'-(dithiodi-2,1-phenylene)bis-
2-Naphthalenamine, N-phenyl-
sec-Butylbenzene
Zinc dibutyldithiocarbamate
Sodium dibutyldithiocarbamate
1-Triazene, 1,3-diphenyl-
1 ,3-Benzenediol, monobenzoate
Phenazopyridine hydrochloride
Dipropyl isocinchomeronate
Hexanoic acid, 2-ethyl-, cobalt(2+) salt
Zinc 2-ethylhexanoate
Benzole acid, butyl ester
4-Hexylresorcinol
1 H-Benzotriazole, 5-methyl-
2-Benzothiazolamine
1 H-lmidazole-1-ethanol, 4,5-dihydro-2-undecyl-
Cyclopentanone, 2-heptyl-
2-Propenoic acid, 2-cyano-, methyl ester
Benzenethiol, 2-methyl-
Benzenethiol, 2-amino-
Phenol, 2,4-diamino-, dihydrochloride
Benzenamine, 2,4,5-trimethyl-
1 ,3-Benzenediol, 4,6-dichloro-
Sodium N-methyl-N-oleoyltaurate
Thiram
Copper dimethyldithiocarbamate
Ziram
1-Butanol, 2-methyl-
Sodium propionate
Potassium N-methyldithiocarbamate
Sodium methyldithiocarbamate
L-Ascorbic acid, 6-hexadecanoate
Phenol, 2,4-dinonyl-
Glutamic acid hydrochloride
Propanoic acid, 2-hydroxy-, butyl ester
Benzenaminium, N,N,N-trimethyl-, chloride
Dimethyl 5-sulphoisophthalate
Limonene
Disodium cyanodithioimidocarbonate
Sodium phenate
Sulfamic acid, cyclohexyl-, monosodium salt
Dodecyl dimethyl benzyl ammonium chloride
Tetradecyl dimethyl benzyl ammonium chloride
Nitrilotriacetic acid
Ethylenediaminetetraacetic acid disodium salt
Propazine
1 ,2,3-Propanetriol, tripropanoate
N,N'-Bis(5-methyl-3-heptyl)-p-phenylenediamine
4,4'-Thiodianiline
Benzene, 1,1'-thiobis-
Sodium Tetradecyl Sulfate
Trisodium (2-hydroxyethyl)ethylenediaminetriacetate
Urea, 1 -ethyl- 3-(5-nitro-2-thiazolyl)-
Pentasodium diethylenetriaminepentaacetate
Methyl acetyl ricinoleate
Tris(2-chloroethyl) phosphite
2-Propenoic acid, 3-phenyl-, (2E)-
Acetic acid, phenylmethyl ester
Benzeneacetonitrile
1-Piperazineethanamine
Acetamide, N-[4-(chloroacetyl)phenyl]-
Benzeneacetonitrile, 4-chloro-
Fenaminosulf
Aramite
Benzenesulfonic acid, 4-decyl-
Phenol, 4-(1 ,1 ,3,3-tetramethylbutyl)-
Estragole
Ethyl acrylate
Nominated
































































































Draft
PCCL3






Yes

















Yes
Yes




Yes





















Yes

Yes



Yes












Yes











Yes










Yes
Yes
Final
PCCL3






Yes

















Yes
Yes




Yes





















Yes

Yes



Yes












Yes











Yes










Yes
Yes
Draft
CCL 3






Yes























Yes























Yes









































Public
Comment
Yes

















Yes











Yes








































Yes
























Final
CCL 3






Yes























Yes























Yes









































CCL 2
































































































CCL1
































































































        A5-21

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
140932
140954
141015
141026
141048
141059
141071
141106
141139
141173
141184
141219
141220
141231
141242
141322
141388
141435
141526
141537
141571
141639
141651
141662
141753
141786
141797
141822
141866
141913
141935
141979
142041
142085
142096
142165
142187
142198
142223
142267
142289
142290
142303
142314
142461
142472
142596
142621
142643
142723
142734
142778
142789
142825
142836
142847
142870
142905
142916
142927
142961
143066
143077
143088
143168
143180
143191
143226
143237
143248
143271
143282
143293
143500
144194
144332
144343
144490
144558
144627
144741
144821
144832
145391
145493
147148
147240
147477
147820
147853
147933
147944
148185
148243
148696
148798
Common Name
Proxan-sodium
Urea, N,N'-bis(hydroxymethyl)-
2-Butenedioic acid (2E)-, iron(2+) salt (1:1)
2-Butenedioic acid (2E)-, bis(2-ethylhexyl) ester
Diisobutyl adipate
2-Butenedioic acid (2Z)-, diethyl ester
Urea, N,N'-bis(methoxymethyl)-
3,5,9-Undecatrien-2-one, 6,1 0-dimethyl-
9-Undecenal, 2,6,10-trimethyl-
Bis[2-(2-butoxyethoxy)ethyl] adipate
Hexanedioic acid, bis(2-butoxyethyl) ester
Ethanolaminoethyl stearamide
9-Octadecenoic acid, 12-hydroxy-, (9Z,12R)-
Methyl-12-hydroxystearate
Methyl ricinoleate
Butyl acrylate
Oxiraneoctanoic acid, 3-octyl-, 2-ethylhexyl ester
Ethanolamine
Sodium ethoxide
Sodium formate
Silane, trichloropropyl-
Pentasiloxane, dodecamethyl-
Sodium bis(2-ethylhexyl)phosphate
Dicrotophos
Butanoyl chloride
Ethyl acetate
Mesityl oxide
Propanedioic acid
2,6-Pyridinediamine
Morpholine, 2,6-dimethyl-
Benzene, 1,3-diethyl-
Ethyl acetoacetate
Aniline hydrochloride
2(1H)-Pyridinone
2-Propenoic acid, 2-methyl-, hexyl ester
2-Butenedioic acid (2Z)-, bis(2-ethylhexyl) ester
Dodecanoic acid, 2,3-dihydroxypropyl ester
Heptanoic acid, 2-propenyl ester
Diallyl glycol carbonate
Acetylethanolamine
1,3-Dichloropropane
Cyclopentene
3-Hexyne-2,5-diol, 2,5-dimethyl-
Sulfuric acid, monooctyl ester, sodium salt
1 ,2-Hydrazinedicarbothioamide
L-Glutamic acid, monosodium salt
Nabam
Hexanoic acid
Piperazine dihydrochloride
Acetic acid, magnesium salt
Glycine, N-(carboxymethyl)-
9-Octadecenoic acid (9Z)-, butyl ester
Dodecanamide, N-(2-hydroxyethyl)-
Heptane
2,4-Hexadienal, (2E,4E)-
Dipropylamine
Decyl sodium sulfate
Lauryl methacrylate
Isopropyl palmitate
Acetic acid, hexyl ester
Butane, 1,1'-oxybis-
Hexamethylenediamine carbamate
Laurie acid
1-Nonanol
1-Hexanamine, N-hexyl-
Potassium oleate
Sodium oleate
Triethylene glycol monobutyl ether
1 ,6-Hexanediamine, N-(6-aminohexyl)-
2,5,8,11,14-Pentaoxapentadecane
1-Hexadecanamine
9-Octadecen-1-ol, (9Z)-
5,8,11,13,16,19-Hexaoxatricosane
Chlordecone
2,2,4-TrimethyH ,3-pentanediol
Disodium hydrogen citrate
Selenium dimethyldithiocarbamate
Fluoroacetic acid
Sodium bicarbonate
Oxalic acid
Sulfathiazole sodium
Sulfamethizole
Sulfapyridine
Musk tibetine
Diaminoanthrarufm
C.I. Pigment Blue 15
Diphenhydramine hydrochloride
1 ,2-Dihydro-2,2,4-trimethylquinoline
Benzenamine, 2,4,6-tribromo-
L-Proline
2-Thiosalicylic acid
Cytarabine
Sodium diethyldithiocarbamate
8-Quinolinol
Propanenitrile, 3-[ethyl(3-methylphenyl)amino]-
Thiabendazole
Nominated

















































































Yes














Draft
PCCL3























Yes

Yes






Yes





Yes














Yes

Yes





















Yes


















Final
PCCL3























Yes

Yes






Yes





Yes














Yes

Yes





















Yes


















Draft
CCL 3























Yes








































































Public
Comment

















































































Yes














Final
CCL 3























Yes








































































CCL 2








































Yes























































CCL1








































Yes























































        AS-22

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
148823
148878
149304
149326
149440
149451
149575
149735
149746
149826
149917
150130
150196
150389
150390
150469
150505
150685
150696
150765
150787
150903
151053
151100
151133
151213
151417
151564
152169
153184
154212
154416
154698
154938
155044
156105
156434
156627
156876
191242
193395
198550
205992
206440
207089
208968
218019
255378
262124
271896
274099
280579
281867
286204
287923
288324
288880
289952
294622
298000
29801 1
298022
298044
298066
298077
298124
298146
298464
298599
298817
299274
299285
299296
299752
299843
300765
300925
301020
301042
301122
301133
302012
302170
303344
303479
303980
304176
304596
305033
306376
306525
306832
307357
309002
311455
311897
Common Name
Melphalan
Propanenitrile, 3-(ethylphenylamino)-
2-Mercaptobenzothiazole
Erythritol
Methanesulfinic acid, hydroxy-, monosodium salt
Tiron
2-Ethylhexanoic acid
Methane, trimethoxy-
Dichloromethylphenylsilane
Carbamodithioic acid, dibutyl-, compd. with N,N-
Benzoic acid, 3,4,5-trihydroxy-
p-Aminobenzoic acid
Phenol, 3-methoxy-
Ethylenediaminetetraacetic acid trisodium salt
(2-Hydroxyethyl)ethylenediaminetriacetic acid
Boric acid (H3BO3), triethyl ester
Merphos
Monuron
Urea, (4-ethoxyphenyl)-
Phenol, 4-methoxy-
Benzene, 1 ,4-dimethoxy-
Butanedioic acid, disodium salt
Benzeneethanol, . alpha. ..alpha.-dimethyl-, acetate
Benzene, 1 ,3-dimethoxy-
Butyl ricinoleate
Sodium lauryl sulfate
Sulfuric acid, monododecyl ester
Aziridine
Schradan
Rutin
LINCOMYCIN
Phenylpropanolamine hydrochloride
Tripelennamine hydrochloride
Urea, N,N'-bis(2-chloroethyl)-N-nitroso-
Zinc 2-mercaptobenzothiazolate
p-Nitrosodiphenylamine
p-Phenetidine
Calcium cyanamide
1-Propanol, 3-amino-
Benzo(g,h,i)perylene
lndeno[1 ,2,3-cd]pyrene
Perylene
Benzo(b)fluoranthene
Fluoranthene
Benzo[k]fluoranthene
Acenaphthylene
Chrysene
1 ,4-Benzodioxin
Dibenzo-p-dioxin
Benzofuran
1 ,3-Benzodioxole
1 ,4-Diazabicyclo[2.2.2]octane
1 ,3,6,8-Tetraazatricyclo(6.2.1 .13,6)dodecane
7-Oxabicyclo[4.1 .0]heptane
Cyclopentane
1 H-lmidazole
1 ,2,4-Triazole
Pyrimidine
Cycled odecane
Methyl parathion
cis-Mevinphos
Phorate
Disulfoton
Phosphorodithioic acid, O,O-diethyl ester
Phosphoric acid, bis(2-ethylhexyl) ester
Acetic acid, oxo-
Potassium bicarbonate
Carbamazepine
Methylphenidate hydrochloride
7H-Furo[3,2-g][1]benzopyran-7-one, 9-methoxy-
D-Gluconic acid, monopotassium salt
Calcium Gluconate
Iron, bis(D-gluconato-. kappa. O1,. kappa. O2)-
Treosulfan
Ronnel
Naled
Aluminum, hydroxybis(octadecanoato-. kappa. O)-
9-Octadecenamide, (9Z)-
Lead(ll) acetate
Oxydemeton-methyl
Phosphorous acid, tris(2-ethylhexyl) ester
Hydrazine
Chloral hydrate
Lasiocarpine
Ochratoxin A
Ubidecarenone
1 H-lsoindole-1 ,3(2H)-dione, 2-(1-methylethyl)-
Potassium sodium tartrate
Chlorambucil
Hydrazine, 1,2-dimethyl-, dihydrochloride
Triclofos
HCFC-123
Perfluorooctylsulfonyl fluoride
Aldrin
Paraoxon
Perfluorotributylamine
Nominated






























Yes




























Yes







Yes




























Draft
PCCL3


Yes



Yes









Yes


















Yes
Yes












Yes












Yes












Yes



Yes

Yes











Yes


Final
PCCL3


Yes



Yes









Yes


















Yes
Yes












Yes












Yes












Yes



Yes

Yes
Yes










Yes


Draft
CCL 3






























































Yes
















Yes

Yes














Public
Comment
Yes





























Yes











Yes
Yes

Yes
Yes




















Yes














Yes










Yes


Final
CCL 3






























































Yes
















Yes

Yes














CCL 2






























































Yes

































CCL1






























































Yes






























Yes


        AS-23

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
314409
315184
315300
316427
319846
319857
319868
320672
320729
328427
328847
32901 1
329715
330541
330552
333186
333200
333415
334485
335579
335671
342698
344047
344729
345788
350038
352932
353593
354143
354234
354256
354325
354336
354585
355420
357573
360689
364761
366187
366701
367124
36751 1
371404
371415
372098
373024
374072
375224
382105
389082
393759
396010
404864
408355
409029
409212
420042
422560
428591
431038
431890
434071
434139
437387
445294
446866
451401
452584
456597
458377
460004
460195
460355
460731
461585
461723
462066
462088
462953
463490
463514
463569
463581
463821
464108
465736
467630
469216
470677
470826
470906
471341
473541
473552
473905
474862
Common Name
Bromacil
Mexacarbate
4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1 ,5-dihydro-
Emetine, dihydrochloride
alpha- Hexachlorocyclohexane
.beta.-Hexachlorocyclohexane
.delta.-Hexachlorocyclohexane
Azacitidine
Benzole acid, 3,5-dichloro-2-hydroxy-
Butanedioic acid, oxo-
Benzene, 1 ,2-dichloro-4-(trifluoromethyl)-
Benzene, 1-isocyanato-3-(trifluoromethyl)-
2,5-Dinitrophenol
Diuron
Linuron
1 ,2-Ethanediamine, dihydrochloride
Potassium thiocyanate
Diazinon
Decanoic acid
Heptane, hexadecafluoro-
PFOA(Perfluorooctanoic acid)
Inosine, 6-S-methyl-6-thio-
Benzene, bromopentafluoro-
5-Thiazolecarboxylic acid, 2-amino-4-(trifluoromethyl)-, ethyl
Pseudoephedrine hydrochloride
3-Acetylpyridine
Diethyl sulfide
Halon 1211
HCFC-121
HCFC-123a
HCFC-124a
Acetyl chloride, trifluoro-
HFC-125
Ethane, 1 ,1 ,1-trichloro-2,2,2-trifluoro-
Hexane, tetradecafluoro-
Brucine
3-beta-coprostanol
Benzenamine, 4-fluoro-3-nitro-
2,2'-Bipyridine
Procarbazine hydrochloride
Phenol, 2-fluoro-
Acetic acid, mercapto-, monosodium salt
Benzenamine, 4-fluoro-
Phenol, 4-fluoro-
Cyanoacetic acid
Nickel(ll) acetate
Ethane, 1,1-dichloro-1,2,2,2-tetrafluoro-
Butanoic acid, heptafluoro-
1-Propene, 3,3,3-trifluoro-2-(trifluoromethyl)-
Nalidixic acid
Benzene, 2-chloro-1 ,3-dinitro-5-(trifluoromethyl)-
2,4,7-Pteridinetriamine, 6-phenyl-
Capsaicin
Sodium palmitate
Cyclan delate
Silicon carbide (SiC)
Cyanamide
HCFC-225ca
Oxirane, trifluoro(trifluoromethyl)-
2,3-Butanedione
HFC-227ea
Oxymetholone
Cholan-24-oic acid, 3-hydroxy-, (3. alpha. ,5. beta. )-
FENTANYL
Benzole acid, 2-fluoro-
Azathioprine
Ethanone, 1,2-diphenyl-
2,3-DIAMINOPYRIDINE
Cyclan delate
Curcumin
Benzene, 1-bromo-4-fluoro-
Cyanogen
HCFC-253fb
HFC-245fa
Dicyanodiamide
2,4-lmidazolidinedione
Benzene, fluoro-
3-Aminopyridine
Ethane, 1 ,1'-[methylenebis(oxy)]bis-
Propadiene
Ketene
Thiocyanic acid
Carbonyl sulfide
2,2-Dimethylpropane
Methane, tribromonitro-
Isodrin
Tris(p-dimethylaminophenyl) methanol
Doxylamine
1 ,4-Cineole
2-Oxabicyclo[2.2.2]octane, 1 ,3,3-trimethyl-
Chlorfenvinphos
Calcium carbonate
Bicyclo[3.1.1]heptan-2-ol,2,6,6-trimethyl-
Bicyclo[3.1.1]heptane, 2,6,6-trimethyl-
Oxopropanedioic acid
equilin
Nominated




Yes









Yes


Yes


Yes















Yes










Yes




































Yes










Yes
Draft
PCCL3
Yes



Yes








Yes
Yes


Yes


Yes






































































Yes




Final
PCCL3
Yes



Yes








Yes
Yes


Yes


Yes






































































Yes



Yes
Draft
CCL 3




Yes








Yes






Yes











































































Public
Comment




Yes
Yes
Yes






Yes
Yes


Yes


Yes















Yes


Yes







Yes











Yes










Yes













Yes


Yes







Yes
Final
CCL 3




Yes








Yes






Yes










































































Yes
CCL 2













Yes
Yes


Yes














































































CCL1













Yes
Yes


Yes














































































        A5-24

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
475207
479458
480160
482893
486124
486259
487683
488233
488415
490799
491043
492808
494031
495545
496117
496151
496720
497187
497198
497392
498817
499127
499752
499832
501360
501531
502443
503742
504030
504201
504245
504290
504609
504632
504665
504778
504881
505293
505486
505522
505577
505602
505715
506127
506309
506514
506592
506683
506774
506876
506934
506967
507095
507200
507551
507700
509148
510156
512561
513359
513371
513495
513531
513746
513860
513882
514103
514363
515037
515980
517099
518478
518821
520456
526261
526738
526750
526954
526998
527071
527093
527208
527537
527606
528290
528449
528745
528949
529339
529340
530574
531760
531828
531851
532025
532274
Common Name
Longifolene
Benzenamine, N-methyl-N,2,4,6-tetranitro-
Morin
C.I. Vat Blue 1
TRIPROLIDINE
9H-Fluoren-9-one
Benzaldehyde, 2,4,6-trimethyl-
Benzene, 1,2,3,4-tetramethyl-
D-Mannitol, 1,6-dibromo-1,6-dideoxy-
Benzoic acid, 2,5-dihydroxy-
2-Cyclohexen-1-ol,3-methyl-6-(1-methylethyl)-
Auramine
Chlornaphazine
C.I. Solvent Orange 3
1H-lndene, 2,3-dihydro-
1 H-lndole, 2,3-dihydro-
3,4-Diaminotoluene
Carbonic dihydrazide
Sodium carbonate
4,6-Di-tert-butyl-m-cresol
Cyclohexanemethanol, . alpha. ..alpha., 4-trimethyl-
1-Propene-1,2,3-tricarboxylic acid
Isopropyl-o-cresol
2,6-Pyridinedicarboxylic acid
PREVENTION 8 (RESVERATROL)
Carbonochloridic acid, phenylmethyl ester
2-Oxepanone
Butanoic acid, 3-methyl-
Piperidine, 2,6-dimethyl-
2,5-Heptadien-4-one, 2,6-dimethyl-
4-Aminopyridine
2-Aminopyridine
1 ,3-Pentadiene
1 ,3-Propanediol
Cyanamide, cyano-
OXAZOLINE
Propanoic acid, 3-nitro-
1,4-Dithiane
Octanedioic acid
Tridecanedioic acid
2-Hexenal
Mustard gas
1,2-Ethanediamine, N,N'-dinitro-
Heptadecanoic acid
Eicosanoic acid
1-Tetracosanol
Methanamine, N-methyl-, hydrochloride
Cyanogen bromide
Cyanogen chloride
Ammonium carbonate
Guanidine, mononitrate
Acetyl bromide
Ethanethioic acid
Propane, 2-chloro-2-methyl-
HCFC-225cb
Borneol
Tetranitromethane
Chlorobenzilate
Trimethyl phosphate
2-Butene, 2-methyl-
1-Propene, 1-chloro-2-methyl-
(S)-2-Aminobutane
2-Butanethiol
Ammonium dithiocarbamate
2-Butanone, 3-hydroxy-
1 ,1-Dichloropropanone
Abietic acid
Fluorocortisone acetate
Sclareol
Propanoic acid, 2-hydroxy-, monoammonium salt
equilenin
Fluorescein, disodium salt
EMODIN
3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione
Benzole acid, 2-hydroxy-, strontium salt (2:1)
Benzene, 1,2,3-trimethyl-
Phenol, 2,3-dimethyl-
D-Gluconic acid
Galactaric acid
D-Gluconic acid, monosodium salt
Copper gluconate
PENTACHLOROANILINE
Isodurene
Mesitol
o-Dinitrobenzene
1 ,2,4-Benzenetricarboxylic acid
3',5'-Dichloromethotrexate
Ammonium salicylate
1-Naphthalenol, 1,2,3,4-tetrahydro-
1(2H)-Naphthalenone, 3,4-dihydro-
Benzoic acid, 4-hydroxy-3,5-dimethoxy-
Phenylalanine, 4-[bis(2-chloroethyl)amino]-
Acetamide, N-[4-(5-nitro-2-furanyl)-2-thiazolyl]-
[1,1'-Biphenyl]-4,4'-diamine, dihydrochloride
2-Naphthalenesulfonic acid sodium salt
2-Chloroacetophenone
Nominated






































































Yes

























Draft
PCCL3











Yes













































Yes
Yes

























Yes











Final
PCCL3











Yes




































Yes








Yes
Yes











Yes













Yes











Draft
CCL 3
































































































Public
Comment




Yes



































Yes







Yes
















Yes




Yes

























Final
CCL 3






































































Yes

























CCL 2
































































































CCL1
































































































        AS-25

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
532321
532434
532821
533584
533744
533879
533960
534076
534134
534156
534178
534225
534521
535808
535875
536334
536607
536903
537008
537928
538238
538410
538750
538932
539480
540181
540385
540498
540545
540590
540636
540692
540727
540738
540841
540885
540976
541026
541413
541424
541731
541855
541913
542187
542563
542756
542881
542927
543271
543497
544014
544161
544172
544401
544638
544763
544854
545062
546565
546689
546805
546894
546930
547579
547580
547648
548629
549188
550447
551939
552169
552307
552454
552896
553264
553548
554007
554121
554132
554847
554950
555102
555317
555351
555373
555431
555759
556525
556616
556672
556821
556887
557040
557051
557073
557200
Common Name
Sodium benzoate
Thiamine mononitrate
C.I. Basic Orange 2, monohydrochloride
Phenol, 2-iodo-
Dazomet
alpha- Aleuritic acid
Sodium sesquicarbonate
Bis(chloromethyl) ketone
Thiourea, N,N'-dimethyl-
Ethane, 1,1-dimethoxy-
Dicesium carbonate
Furan, 2-methyl-
4,6-Dinitro-o-cresol
m-Chlorobenzoic acid
Benzole acid, 3,5-diamino-
Ethionamide
Cumic alcohol
Benzenamine, 3-methoxy-
Cerium triacetate
Acetamide, N-(S-methylphenyl)-
Octanoic acid, 1,2,3-propanetriyl ester
Benzenamine, 4,4'-azobis-
Cyclohexanamine, N,N'-methanetetraylbis-
Benzene, (2-methylpropyl)-
1 ,4-Benzenedimethanamine
Butanoic acid, pentyl ester
Phenol, 4-iodo-
Ethene, 1 ,2-dibromo-
1-Chloropropane
1 ,2-Dichloroethylene
1,2-Ethanedithiol
Formic acid, ammonium salt
Sodium thiocyanate
1 ,2-Dimethylhydrazine
2,2,4-Trimethylpentane
tert-Butyl acetate
Cyclohexasiloxane, dodecamethyl-
Decamethylcyclopentasiloxane
Ethyl chloroformate
Isopropyl nitrite
m-Dichlorobenzene
3-Heptanone, 5-methyl-
Muscone
Cyclohexane, chloro-
Nitrous acid, 2-methylpropyl ester
1 ,3-Dichloropropene
Bis(chloromethyl) ether
1 ,3-Cyclopentadiene
Carbonochloridic acid, 2-methylpropyl ester
2-Heptanol
Butane, 1,1'-oxybis[3-methyl-
Nitrous acid, butyl ester
Formic acid, calcium salt
Dibutyl sulfide
Tetradecanoic acid
Hexadecane
Dotriacontane
Trichloroacetonitrile
Cyclotetrasiloxane, octaphenyl-
Tetraisopropyl titan ate
Thujone
Acetic acid, lithium salt
Magnesium carbonate
Acid orange 6
Methyl orange
Propanoic acid, 2-hydroxy-, methyl ester
Crystal violet
Amitriptyline hydrochloride
1 H-lsoindole-1 ,3(2H)-dione, 2-methyl-
2-Aminoacetophenone
o-Nitrobenzoic acid
Trimellitic anhydride
Benzene, 1-(chloromethyl)-2-methyl-
Benzaldehyde, 2-nitro-
4,4'-Bipyridine
Benzole acid, lithium salt
2,4-Dichloroaniline
Propanoic acid, methyl ester
Lithium carbonate
m-Nitrophenol
Trimesic acid
beta-Phellandrene
2-Propanol, aluminum salt
Hexadecanoic acid, aluminum salt
Neburon
Octadecanoic acid, 1,2,3-propanetriyl ester
Ethanol, aluminum salt
Glycidol
Methyl isothiocyanate
Octamethyl Cyclotetrasiloxane
2-Buten-1-ol, 3-methyl-
Guanidine, nitro-
Octadecanoic acid, magnesium salt
Zinc stearate
9-Octadecenoic acid (9Z)-, zinc salt
Zinc, diethyl-
Nominated
































































































Draft
PCCL3
Yes




































Yes


Yes




Yes
Yes
Yes























Yes


Yes



Yes








Yes

Yes






Final
PCCL3
Yes




































Yes


Yes




Yes
Yes
Yes









Yes













Yes


Yes



Yes








Yes

Yes






Draft
CCL 3
































































































Public
Comment







Yes
































Yes
















Yes






































Final
CCL 3
































































































CCL 2













































Yes


















































CCL1













































Yes


















































        AS-26

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
557288
557346
557595
557755
557959
557982
562743
563042
563122
563257
563417
563439
563462
563473
563586
563702
563713
563804
563848
564250
565617
565800
569619
569642
573568
574936
575440
576249
576261
577117
578541
579668
581420
583391
583584
583608
583788
584032
584087
584792
584849
585079
586389
586629
586765
587984
588465
589388
590001
590012
590023
590170
590181
590192
590216
590294
590465
590863
591128
591220
591275
591311
591355
591764
591786
591979
592416
592427
592450
592518
592847
59351 1
593602
593817
593851
593942
594047
594150
594183
594207
594274
594423
594650
594729
596032
597251
597319
597433
597820
598027
598550
598561
598629
598709
598721
598776
Common Name
Propanoic acid, zinc salt
Zinc acetate
Tetracosanoic acid
VINYL ALCOHOL
Bromodiiodomethane
2-Chloropropene
4-Terpineol
Phosphoric acid, tris(S-methylphenyl) ester
Ethion
Stannane, dibutyldifluoro-
Semicarbazide hydrochloride
Aluminum, dichloroethyl-
2-Methyl-1-butene
3-Chloro-2-methyl-1-propene
1,1-Dichloropropene
Bromonitromethane
Carbonic acid, iron(2+) salt (1 :1)
Methyl isopropyl ketone
3-Chloro-2-butanol
Doxycycline
2-Pentanone, 3-methyl-
3-Pentanone, 2,4-dimethyl-
C.l. Basic Red 9, monohydrochloride
Malachite green
2,6-Dinitrophenol
29H,31H-Phthalocyanine
1,6-Naphthalenediol
Phenol, 2,3-dichloro-
2,6-Dimethylphenol
Bis(2-ethylhexyl) sodium sulfosuccinate
Benzenamine, 2-ethyl-
Benzenamine, 2,6-diethyl-
2,6-Dimethylnaphthalene
2H-Benzimidazole-2-thione, 1 ,3-dihydro-
3,4-Dimethylpyridine
Cyclohexanone, 2-methyl-
Phenol, 2,5-dichloro-
1 ,2-Butanediol
Potassium carbonate
Allethrin
Toluene-2,4-diisocyanate
tert-Butyl methacrylate
Benzole acid, 3-methoxy-
Cyclohexene, 1-methyl-4-(1-methylethylidene)-
Benzoic acid, 4-bromo-
C.l. Acid Yellow 36, monosodium salt
N-BENZYLACETAMIDE
3-Hexanone
Potassium sorbate
Propanoic acid, butyl ester
Acetic acid, chloro-, butyl ester
Acetonitrile, bromo-
cis-2-Butene
1,2-Butadiene
1-Chloro-1-propene
Formic acid, potassium salt
Betaine hydrochloride
Butanal, 3-methyl-
2(3H)-Furanone, 5-methyl-
3,5-Dimethylpyridine
Phenol, 3-amino-
Benzaldehyde, 3-methoxy-
Phenol, 3,5-dichloro-
Hexane, 2-methyl-
2-Hexanone
2-Butene, 1-chloro-
1-Hexene
1 ,5-Hexadiene
1,4-Hexadiene
4-Pentenenitrile
Formic acid, butyl ester
Methanamine, hydrochloride
Vinyl bromide
Methanamine, N,N-dimethyl-, hydrochloride
Carbonic acid, compd. with guanidine (1:2)
dibromoiodomethane
dichloroiodomethane
tribromochloromethane
dibromodichloromethane
2,2-Dichloropropane
Stannane, tetramethyl-
Perchloromethyl mercaptan
Trichloroacetamide
Ethane, 1,1-dichloro-1-nitro-
4',5'-Dibromofluorescein
Phosphonic acid, 4-morpholinyl-, dimethyl ester
Propanal, 3-hydroxy-2,2-dimethyl-
2,2-Dimethylbutanedioic acid
Phosphorothioic acid, O,O,O-triphenyl ester
Phosphoric acid, diethyl ester
Methyl carbamate
Ethanamine, N,N-dimethyl-
Carbonic acid, manganese(2+) salt (1:1)
Dibromoacetamide
Propanoic acid, 2-bromo-
Propane, 1,1,2-trichloro-
Nominated















Yes



Yes












































































Draft
PCCL3








Yes




Yes














Yes
Yes




































Yes























Yes





Final
PCCL3








Yes




Yes














Yes
Yes




































Yes









Yes













Yes





Draft
CCL 3








Yes























































































Public
Comment




Yes



Yes






Yes



Yes































Yes























Yes
Yes
Yes




Yes










Yes


Final
CCL 3
































































































CCL 2














Yes
































































Yes
















CCL1














Yes
































































Yes
















        AS-27

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
598787
598914
59961 1
599644
599791
602017
602879
603350
603361
604751
606202
606213
608253
608719
608935
609198
609201
609234
609665
609723
609938
610399
611143
611198
611325
611596
611927
612124
612828
612839
614459
614686
614802
614959
615054
615203
615543
615587
616217
616239
616308
616386
616455
616477
616911
617845
617890
617947
618451
619158
619170
619501
619669
619670
619738
619807
620177
620224
621238
621421
621647
621716
621829
622253
622402
622457
622515
622968
622979
623030
623154
623303
623336
623369
623427
623847
623916
624180
624486
624544
624646
624839
624920
625285
625456
625558
626028
626175
626380
626391
626437
626482
626608
626619
626642
626675
Common Name
Propanoic acid, 2-chloro-
Methane, dibromonitro-
Benzenamine, 3,3'-sulfonylbis-
Phenol, 4-(1-methyl-1-phenylethyl)-
Salicylazosulfapyridine
2,3-Dinitrotoluene
5-Nitroacenaphthene
Phosphine, triphenyl-
Stibine, triphenyl-
Oxazepam
2,6-Dinitrotoluene
2,6-Dinitrochlorobenzene
1 ,3-Benzenediol, 2-methyl-
Phenol, pentabromo-
Pentachlorobenzene
3,4,5-Trichlorophenol
1,4-Benzenediamine, 2,6-dichloro-
Phenol, 2,4,6-triiodo-
Benzamide, 2-chloro-
Benzenamine, N,N,2-trimethyl-
2,6-Dinitro-p-cresol
3,4-Dinitrotoluene
Benzene, 1-ethyl-2-methyl-
Benzene, 1-chloro-2-(chloromethyl)-
8-Methylquinoline
1 ,7-dimethylxanthine
Urea, N,N'-dimethyl-N,N'-diphenyl-
Benzene, 1,2-bis(chloromethyl)-
3,3'-Dimethylbenzidine dihydrochloride
3,3'-Dichlorobenzidine dihydrochloride
tert-Butyl peroxybenzoate
Benzene, 1-isocyanato-2-methyl-
Acetamide, N-(2-hydroxyphenyl)-
N-Nitroso-N-ethylurethane
2,4-Diaminoanisole
Benzothiazole, 2-chloro-
Benzene, 1 ,2,4-tribromo-
Phenol, 2,4-dibromo-
Butane, 1,2-dichloro-
1-Propanol, 2,3-dichloro-
1,2-Propanediol, 3-amino-
Methyl carbonate
2-Pyrrolidone
1 H-lmidazole, 1-methyl-
Acetylcysteine
Formamide, N,N-diethyl-
2-Furanmethanamine
Benzenemethanol, . alpha.,. alpha.-dimethyl-
Phenol, 3-(1-methylethyl)-
2,5-Dinitrotoluene
Benzole acid, 2-amino-4-nitro-
Benzoic acid, 4-nitro-, methyl ester
Benzole acid, 4-formyl-
Benzoic acid, 4-hydrazino-
Benzenemethanol, 4-nitro-
Benzamide, 4-nitro-
Phenol, 3-ethyl-
Benzonitrile, 3-methyl-
Benzene, 1 ,3,5-trimethoxy-
Acetamide, N-(S-hydroxyphenyl)-
N-Nitroso-di-n-propylamine (NDPA)
Decanoic acid, 1,2,3-propanetriyl ester
2-Propenoic acid, 3-phenyl-
Benzene, (2-chloroethenyl)-
4-Morpholineethanol
Acetic acid, cyclohexyl ester
Urea, (4-methylphenyl)-
Benzene, 1-ethyl-4-methyl-
p-Methyl styrene
Benzonitrile, 4-chloro-
3-Buten-2-one, 4-(2-furanyl)-
2-Propenal, 3-(2-furanyl)-
Glycine, ethyl ester, hydrochloride
2-Pentenal, 2-methyl-
Butanoic acid, methyl ester
1 ,2-Propanediol, diacetate
2-Butenedioic acid (2E)-, diethyl ester
1 ,4-Phenylenediamine dihydrochloride
2-Butenedioic acid (2Z)-, dimethyl ester
Propanoic acid, pentyl ester
trans- 2-Butene
Methyl isocyanate
Methyl disulfide
Butanenitrile, 3-methyl-
Acetic acid, methoxy-
Isopropyl formate
Phenol, 3-iodo-
1 ,3-Benzenedicarbonitrile
sec-Amyl acetate
Benzene, 1 ,3,5-tribromo-
3,5-Dichloroaniline
6-Methyluracil
Pyridine, 3-chloro-
4-CHLOROPYRIDINE
4-Pyridinol
Piperidine, 1-methyl-
Nominated

Yes























Yes


































Yes



































Draft
PCCL3




























Yes













Yes

















Yes
























Yes










Final
PCCL3




























Yes













Yes

















Yes
























Yes










Draft
CCL 3




























































Yes



































Public
Comment

Yes








Yes














Yes

































Yes
Yes



































Final
CCL 3




























































Yes



































CCL 2










Yes





















































































CCL1










Yes





















































































        AS-28

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
626868
627305
627930
628024
628137
628637
628819
628875
628966
629083
629118
629141
629152
629196
629254
629505
629594
629629
629709
629732
629787
629801
629969
630104
630160
630206
631618
631641
632213
632791
632995
633034
633965
634662
634935
635223
636215
636533
637070
637127
637923
638073
638379
638380
638539
638653
638733
639587
640197
640686
643221
643287
643436
643798
644973
645625
646060
646139
65051 1
652675
657249
657272
657841
659701
661198
674828
675627
676584
677214
680319
681572
681845
682097
682111
683103
683181
683727
684162
684935
688379
688744
688846
689112
689123
689974
690391
693072
693210
693232
693334
693367
693549
693958
693981
694837
695341
Common Name
Monoethyl adipate
1-Propanol, 3-chloro-
Dimethyl adipate
Hexanamide
Pyridine hydrochloride
n-Amyl acetate
Butane, 1-ethoxy-
Acetonitrile, 2,2'-iminobis-
1,2-Ethanediol, dinitrate
Heptanenitrile
1 ,6-Hexanediol
Ethylene glycol diethyl ether
1,2-Ethanediol, diformate
Dipropyl disulfide
Dodecanoic acid, sodium salt
Tridecane
Tetradecane
Pentadecane
1-Hexadecanol, acetate
1-Hexadecene
Heptadecane
Hexadecanal
1-Eicosanol
Selenourea
HALOGENATED ETHANES OS (1 ,1 , 1 ,2-
1,1,1,2-Tetrachloroethane
Ammonium acetate
Dibromoacetic acid
1,1,3,3-Tetrachloropropanone
1 ,3-lsobenzofurandione, 4,5,6,7-tetrabromo-
C.l. Basic Violet 14
C.I. Basic Green 1
C.I. Acid Orange 7, monosodium salt
1 ,2,3,4-Tetrachlorobenzene
Benzenamine, 2,4,6-trichloro-
Benzenamine, 4-chloro-3-nitro-
o-Toluidine hydrochloride
1 ,3-Benzenedicarboxylic acid, diethyl ester
Clofibrate
Octadecanoic acid, aluminum salt
Propane, 2-ethoxy-2-methyl-
Butanoic acid, 4-chloro-3-oxo-, ethyl ester
Butanedial
Manganous acetate
Tridecanoic acid
Octadecanenitrile
chlorodiiodomethane
Triphenyltin chloride
Fluor oacetamide
D-Valine
Erythromycin octadecanoate (salt)
Benzenamine, 2-(1-methylethyl)-
Benzeneacetic acid, 2,4-dinitro-
1 ,2-Benzenedicarboxaldehyde
Phosphonous dichloride, phenyl-
2-Ethyl-3-propylacrolein
1 ,3-Dioxolane
Octadecanoic acid, 2-methylpropyl ester
Sodium trichloroacetate
D-Glucitol, 1,4:3,6-dianhydro-
metformin
L-Lysine, monohydrochloride
Benzenesulfonic acid, 4-methyl-, sodium salt
Butanoic acid, 3-methyl-, 3-methylbutyl ester
1-Docosanol
Diketene
Silane, dichloromethyl(3,3,3-trifluoropropyl)-
Magnesium, chloromethyl-
1-Propene, 3,3,3-trifluoro-
Hexamethylphosphoramide
2,2-Dimethylpentanedioic acid
Silicic acid (H4SIO4), tetramethyl ester
1-Butanol, 2,2-bis[(2-propenyloxy)methyl]-
1 ,3-Propanediol, 2-ethyl-2-[(2-propenyloxy)methyl]-
Laurylbetain
Dibutyltin dichloride
Acetamide, 2,2-dichloro-
2-Propanone, 1 ,1 ,1 ,3,3,3-hexafluoro-
N-Nitroso-N-methylurea
9-Octadecenoic acid (9Z)-, aluminum salt
Boric acid (H3BO3), tributyl ester
2-Propenoic acid, 2-methyl-, 2-ethylhexyl ester
Urea, (1-methylpropyl)-
2-Propenoic acid, 1-methylethyl ester
Vinyl acetylene
HFC-236fa
Ethane, 1-chloro-2-(ethylthio)-
Diethylene glycol dinitrate
Dodecanedioic acid
Hexadecylbetaine
Propanoic acid, 3,3'-thiobis-, dioctadecyl ester
2-Decanone
Thiazole, 4-methyl-
1 H-lmidazole, 2-methyl-
1 ,2-Cyclohexanediamine
2-Pyridinamine, 4-methyl-
Nominated








































Yes



















Yes



































Draft
PCCL3

























Yes










Yes


















Yes



















Yes


Yes

















Final
PCCL3

























Yes










Yes


















Yes



















Yes


Yes

















Draft
CCL 3

























Yes






































































Public
Comment



























Yes
Yes









Yes

Yes





Yes













Yes















Yes



















Final
CCL 3

























Yes






































































CCL 2
































































































CCL1
































































































        AS-29

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
695534
699172
700061
700130
701644
705862
706149
707619
709988
713951
716790
719222
719324
719595
723466
728405
729464
732116
732263
738705
741582
745653
753731
755737
756796
756809
759739
759944
760236
760678
760930
762049
763291
763326
763699
764410
764998
765128
765300
765344
766096
767000
767157
768003
768525
770127
770354
780698
785308
786196
789026
789617
791286
791311
793248
811972
812000
812044
813785
813945
814493
814711
814788
814802
814948
815178
818086
818611
821487
822060
822128
822162
822366
822877
823405
824782
824793
826368
827941
828002
830137
831527
834128
834286
835712
836306
838857
839907
840653
842079
842182
842193
860220
865214
866820
866842
Common Name
Dimethadione
2-Butanone, 4-(2-furanyl)-
PREVENTION 4 (INDOLE-3-CARBINOL)
1 ,4-Benzenediol, 2,3,5-trimethyl-
Phosphoric acid, monophenyl ester
2H-Pyran-2-one, tetrahydro-6-pentyl-
2(3H)-Furanone, 5-hexyldihydro-
3-Methyl-1-phenyl-2-phospholene 1 -oxide
Propanil
2H-Pyran-2-one, 6-heptyltetrahydro-
1 H-Benzimidazole, 2-phenyl-
2,6-Di-tert-butyl-p-benzoquinone
Tetrachloroterephthaloyl chloride
Methanone, (2-amino-5-chlorophenyl)phenyl-
Sulfamethoxazole
Phenol, 2,6-bis(1 ,1-dimethylethyl)-4-nitro-
Morpholine, 4,4'-(dithiodicarbonothioyl)bis-
Phosmet
Phenol, 2,4, 6-tris(1,1-dimethylethyl)-
Trimethoprim
Bensulide
Prostaglandin E1
Dimethyltin dichloride
Methyl 3-methoxytetrafluoropropanoate
Phosphonic acid, methyl-, dimethyl ester
Phosphorodithioic acid, O,O-dimethyl ester
N-Nitroso-N-ethylurea
EPIC
3,4-Dichloro-1-butene
Hexanoyl chloride, 2-ethyl-
Methacrylic anhydride
Phosphonic acid, diethyl ester
1-Pentene, 2-methyl-
3-Buten-1-ol, 3-methyl-
Propanoic acid, 3-ethoxy-, ethyl ester
1 ,4-Dichloro-2-butene
Ethene, 1 ,1'-[oxybis(2,1-ethanediyloxy)]bis-
3,6,9,1 2-Tetraoxatetradeca-1 , 1 3-diene
Cyclopropanamine
Glycidylaldehyde
Piperidine, 1-ethyl-
Benzonitrile, 4-hydroxy-
2-Pyrimidinamine, 4,6-dimethyl-
Benzene, [(1 E)-1-methyl-1-propenyl]-
Benzenamine, N-(l-methylethyl)-
Phenyl dichlorophosphate
2-Propanol, 1-phenoxy-
Silane, triethoxyphenyl-
Benzamide, 4-amino-N-(4-aminophenyl)-
Carbophenothion
o,p'-DDT
beta-THIOGUANIDINE DEOXYRIBOSIDE
Phosphine oxide, triphenyl-
Silanol, triphenyl-
Santoflex 1 3
HFC-134a
Phosphoric acid, monomethyl ester
HCFC-123b
Phosphoric acid, dimethyl ester
Calcium citrate
Diethyl chlorophosphate
Calcium thioglycolate
3-Buten-2-one, 3-methyl-
Propanoic acid, 2-hydroxy-, calcium salt (2:1)
Stannous oxalate
Butanoic acid, 3,3-dimethyl-2-oxo-
Dibutyltin oxide
2-Hydroxyethyl acrylate
2,2'-Dichlorodiethylamine hydrochloride
Hexamethylene-1 ,6-diisocyanate
Sodium myristate
Sodium stearate
1 H-lmidazole, 4-methyl-
Cyclohexanone, 2-chloro-
2,6-Diaminotoluene
p-Nitrophenol sodium salt
Benzenesulfinic acid, 4-methyl-, sodium salt
Tempidon
Benzenamine, 2,6-dibromo-4-nitro-
Dimethoxane
Cycled odecanone
Phenol, 2-amino-4,6-dinitro-, monosodium salt
Ametryn
Phenformin hydrochloride
Benzoxazole, 2-(4-methylphenyl)-
Benzenamine, 4-nitro-N-phenyl-
Phosphoric acid, diphenyl ester
Tris(2-hydroxyethyl) isocyanurate
Dimethyl 2,6-naphthalenedicarboxylate
C.I. Solvent Yellow 14
7-Hydroxy-1,3-naphthalenedisulfonic acid dipotassium salt
1 ,3-Naphthalenedisulfonic acid, 7-hydroxy-, disodium salt
C.I. Acid Blue 74
Vincaleukoblastine
Cupric citrate
Potassium Citrate
Nominated














Yes


Yes

Yes












































































Draft
PCCL3

















Yes


Yes

Yes




Yes
Yes

























Yes











Yes
Yes

Yes












Yes






Yes






Final
PCCL3

















Yes


Yes

Yes




Yes
Yes

























Yes











Yes
Yes

Yes












Yes






Yes






Draft
CCL 3




















Yes











































































Public
Comment














Yes


Yes

Yes












































































Final
CCL 3




















Yes











































































CCL 2



























Yes




































































CCL1



























Yes




































































        AS-30

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
867130
867549
867812
868144
868779
868859
869249
869294
870086
870724
872059
872504
873325
873949
874602
882097
882337
886500
887547
900958
915673
917613
917704
918003
918014
918047
918525
919302
919313
920376
920661
921039
922689
923024
923262
924163
924425
925600
926578
927071
927628
928654
928723
928961
929066
929771
930223
930552
930687
930698
931362
933482
934736
936492
939480
940410
941695
944229
947046
950107
950356
950378
952238
957517
959262
959524
959988
961115
961228
968810
971153
980267
980712
982570
989388
989515
991844
992596
993135
993168
993431
994058
998301
998403
999213
999815
999973
1000824
1002626
1002842
1005670
1007289
1009616
1009934
1017567
1020844
Common Name
Acetic acid, (diethoxyphosphinyl)-, ethyl ester
1 ,1-Dibromopropanone
Sodium pantothenate
Potassium bitartrate
Hydroxyethyl methacrylate
Dimethyl hydrogen phosphite
Ethanamine, 2-chloro-N,N-diethyl-, hydrochloride
2-Propene-1,1-diol, diacetate
Stannane, dioctyloxo-
Methanesulfonic acid, hydroxy-, monosodium salt
1-Decene
N- Methyl- 2-pyrrolidone
Benzonitrile, 2-chloro-
Cyclohexanone, 3,3,5-trimethyl-
Benzoyl chloride, 4-methyl-
Clofibric acid (Clofibrate metabolite)
Disulfide, diphenyl
Terbutryn
Dacthal mono-acid degradate
Fentin acetate
C.I. Acid Red 27, trisodium salt
Cyanic acid, sodium salt
Acetic acid, lanthanum(3+) salt
1 ,1,1-Trichloropropanone
Bromodichloronitromethane
Acetaldehyde sodium bisulfite
1-Propanol, 2,2-dinitro-
1-Propanamine, S-(triethoxysilyl)-
Propanenitrile, S-(triethoxysilyl)-
2-Propenenitrile, 2-chloro-
1,1,1,3,3,3-Hexafluoro-2-propanol
1 ,1,3-Trichloropropanone
Acetic acid, oxo-, methyl ester
2-Propenamide, N-(hydroxymethyl)-2-methyl-
2-Propenoic acid, 2-methyl-, 2-hydroxypropyl ester
N-Nitrosodi-n-butylamine
N-Methylolacrylamide
2-Propenoic acid, propyl ester
2-Butene, 1,3-dichloro-
tert-Butyl peroxypivalate
1-Butanamine, N,N-dimethyl-
Silane, trichlorohexyl-
Disodium iminodiacetate
3-Hexen-1-ol, (3Z)-
Ethanol, 2-(2-aminoethoxy)-
Methyl docosanoate
Oxirane, ethenyl-
N-nitrosopyrrolidine (NPYR)
2-Cyclohexen-1-one
Sodium benzenethiolate
1 H-lmidazole, 2-ethyl-4-methyl-
Cyclohexanol, 3,3,5-trimethyl-, (1R,5R)-rel-
Benzene, 1-chloro-4-(methylsulfinyl)-
1 H-lmidazole, 4,5-dihydro-2-phenyl-
Benzoic acid, 1-methylethyl ester
Silane, trichloro(2-phenylethyl)-
1H-Pyrrole-2,5-dione, 1-phenyl-
Fonofos
Cycled odecalactam
Mephosfolan
Methyl paraoxon
Methidathion
3,6-Acridinediamine, monohydrochloride
Diphenamid
Bis(2-hydroxyethyl) terephthalate
1 ,3,5-Triacryloylhexahydrotriazine
. alpha. -Endosulfan
Tetrachlorvinphos
Azinphos-methyl-oxon
Acetohexamide
Piperidine, 1,1'-(hexathiodicarbonothioyl)bis-
C.l. Pigment Red 122
Brompheniramine maleate
Chloramphenicol sodium succinate
C.I. Basic Red 1
(-)-Epigallocatechin gallate (85% (-)-epigallocatechin gallate,
Irganox RA565
C.I. Direct Red 2, disodium salt
METHYL PHOSPHONIC ACID
Stannane, trichloromethyl-
Phosphonothioic dichloride, ethyl-
Butane, 2-methoxy-2-methyl-
Triethoxysilane
Phosphine, tributyl-
2-Butenedioic acid (2Z)-, di-2-propenyl ester
Chlormequat chloride
Silanamine, 1 ,1 ,1-trimethyl-N-(trimethylsilyl)-
Urea, (hydroxymethyl)-
Decanoic acid, sodium salt
Pentadecanoic acid
Morpholine, 4-butyl-
Desisopropylatrazine
Ethanone, 1,1'-(1,4-phenylene)bis-
Cyclotrisilazane, 2,2,4,4,6,6-hexamethyl-
Methanol, (1 ,3,5-triazine-2,4,6-triyltriimino)tris-
Cyclotetrasilazane, 2,2,4,4,6,6,8,8-octamethyl-
Nominated
























Yes
























































Yes









Yes




Draft
PCCL3




Yes
Yes





Yes























Yes
Yes





Yes




Yes









Yes

































Yes




Final
PCCL3




Yes
Yes





Yes











Yes











Yes
Yes





Yes




Yes









Yes

































Yes




Draft
CCL 3











Yes



































Yes
















































Public
Comment

Yes









Yes



Yes







Yes
Yes






Yes



Yes











Yes


















Yes














Yes














Final
CCL 3











Yes



































Yes
















































CCL 2


















Yes






































Yes






































CCL1


















Yes






































Yes






































        A5-31

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
1025156
1031078
1047161
1064488
1066337
1067330
1067534
1068275
1070004
1070015
1070037
1070708
1070786
1071223
1072522
1072679
1072715
1073729
1074824
1075769
1076977
1077561
1079216
1087214
1100885
1103384
1103395
1111393
1111780
1112396
1113388
1114712
1115204
1116547
1116707
1116730
1116763
1117415
1117971
1118123
1118463
1119400
1119977
1120010
1120043
1120214
1120361
1120714
1121784
1122583
1123859
1125219
1126789
1131186
1132612
1134049
1134232
1135246
1139306
1141384
1156190
1162658
1163195
1176085
1184641
1185097
1185553
1185575
1185815
1187037
1187935
1190165
1191157
1191168
1191500
1191793
1192525
1192627
1193813
1194656
1198556
1203174
1203867
1208522
1210351
1212299
1214397
1220946
1222055
1241947
1248186
1260179
1271198
1271245
1300216
1300716
Common Name
1 ,3,5-Triallyl isocyanurate
Endosulfan sulfate
Quino[2,3-b]acridine-7,14-dione, 5,12-dihydro-
C.l. Acid Black 1, disodium salt
Ammonium bicarbonate
Stannane, bis(acetyloxy)dibutyl-
Tris(2-methoxyethoxy)vinylsilane
2,5-Dimethyl-2,5-di(t-butylperoxy)hexyne-3
Aluminum, trioctyl-
1-Decanamine, N,N-didecyl-
2-Ethylhexyl dihydrogen phosphate
2-Propenoic acid, 1,4-butanediyl ester
Propane, 1,1,1,3-tetrachloro-
Propanenitrile, 3-(trichlorosilyl)-
1-Aziridineethanol
3-lsoxazolamine, 5-methyl-
1,3,4-Thiadiazolidine-2,5-dithione
Phenol, 4-(methylthio)-
1 H-lsoindole-1 ,3(2H)-dione, potassium salt
Propanenitrile, S-(phenylamino)-
1,4-Cyclohexanedicarboxylic acid
Benzenesulfonamide, N-ethyl-2-methyl-
[1,1'-Biphenyl]-2,5-diol
Diallyl isophthalate
Phosphonium, triphenyl(phenylmethyl)-, chloride
C.I. Pigment Red 49, barium salt (2:1)
C.I. Pigment Red 49, calcium salt (2:1)
Acetyldigitoxin
Ammonium carbamate
Silane, dimethoxydimethyl-
Diammonium oxalate
Pebulate
Hydroxypivalyl hydroxypivalate
N-Nitrosodiethanolamine
Aluminum, tributyl-
Aluminum, trihexyl-
1-Octanamine, N,N-dioctyl-
3,5,9-Undecatrien-2-one, 3,6,10-trimethyl-
Methanamine, N-methoxy-
Urea, (1,1-dimethylethyl)-
Stannane, butyltrichloro-
Pentanedioic acid, dimethyl ester
Tetradecyl trimethyl ammonium bromide
1-Hexadecanol, hydrogen sulfate, sodium salt
Sulfuric acid, monooctadecyl ester, sodium salt
Undecane
1-Tetradecene
1 ,3-Propane sultone
3-HYDROXY-6-METHYLPYRIDINE
4-(Dimethylamino)pyridine
2-Phenylpropanol-1
Ketoisophorone
Benzenamine, N-butyl-
1 H-Pyrazol-5-amine, 3-methyl-1-phenyl-
4-Morpholinepropanesulfonic acid
2,3,4,5-Tetrachloro-6-(trichloromethyl)pyridine
Cycloate
2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-
(-)-beta-Caryophyllene epoxide
2,6-Naphthalenedicarboxylic acid
Tolazamide
Aflatoxin B1
Decabromodiphenyl ether
Phenyltoloxamine citrate
Cupric carbonate
Ethanesulfenyl chloride, 1,1,2,2-tetrachloro-
Silane, trimethoxymethyl-
Ferric ammonium citrate
Stannane, dibutylbis(dodecylthio)-
Urea, tetraethyl-
Ethene, trifluoro(trifluoromethoxy)-
Butanenitrile, 4-(dichloromethylsilyl)-
Aluminum, hydrobis(2-methylpropyl)-
2-Buten-1-ol, 3-methyl-, acetate
1-Tetradecanol, hydrogen sulfate, sodium salt
Barium cadmium stearate
4,5-Dichloro-1,2-dithiacyclopentenone
Ethanone, 1-(2-furanyl)-
Cyclohexanemethanol, .alpha.-methyl-
Dichlobenil
Tetrachlorocatechol
1 H-lndene, 2,3-dihydro-1 ,1 ,2,3,3-pentamethyl-
Ethanone,2,2-dichloro-1-(2,4,5-trichlorophenyl)-
Benzenamine, 2-[(4-aminophenyl)methyl]-
Dibenzsuberone
Thiourea, N,N'-dicyclohexyl-
1 H-Purin-6-amine, N-(phenylmethyl)-
4-Amino-1-methylaminoanthraquinone
Galaxolide
Phosphoric acid, 2-ethylhexyl diphenyl ester
C.I. Pigment Red 49
C.I. Natural Red 4
Titanocene dichloride
Chromocene
Dichloroethane
Xylenol
Nominated
































































































Draft
PCCL3




























Yes
















Yes
















Yes

































Final
PCCL3




























Yes
















Yes
















Yes

































Draft
CCL 3
































































































Public
Comment













































Yes
















Yes

























Yes







Final
CCL 3
































































































CCL 2
































































































CCL1
































































































        A5-32

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
1300727
1300738
1302427
1302789
1303282
1303862
1303964
1304296
1304763
1305620
1305788
1305799
1306383
1307966
1309428
1309484
1310538
1310583
1310732
1312761
1312818
1313139
1313275
1313822
1313979
1313991
1314132
1314201
1314223
1314234
1314369
1314563
1314621
1314803
1314847
1314870
1314983
1317335
1317357
1317608
1319466
1319773
1320189
1320510
1321331
1321546
1321637
1321693
1321740
1321875
1321944
1322210
1322754
1322936
1322970
1322981
1322992
1323382
1323393
1323428
1323611
1323655
1324114
1324556
1324761
1325377
1325822
1326825
1327339
1327419
1327442
1327577
1328536
1330387
1330434
1330616
1330763
1330785
1330865
1331120
1332656
1333079
1333171
1333397
1333831
1334787
1335326
1335462
1335666
1336216
1337855
1338234
1338392
1338416
1338438
1343880
Common Name
Sodium xylenesulfonate
Xylidine
Aluminate (AIO21-), sodium
Bentonite
Arsenic(V) pentoxide
Boric oxide
Borax
Barium peroxide (Ba(O2))
Bismuth oxide
Calcium hydroxide
Calcium oxide
Calcium peroxide
Cerium oxide
Cobalt(ll)oxide
Magnesium hydroxide
Magnesium oxide
Germanium oxide
Potassium hydroxide
Sodium hydroxide
Potassium silicate
Lanthanum oxide
Manganese dioxide
Molybdenum trioxide
Sodium sulfide
Neodymium oxide
Nickel(ll) oxide
Zinc oxide
Thorium dioxide
Zinc peroxide
Zirconium oxide
Yttrium oxide
Phosphorus pentoxide
Vanadium pentoxide
Phosphorus pentasulfide
Zinc phosphide
Lead sulfide
Zinc sulfide
Molybdenum sulfide
Manganese tetraoxide
Hematite
Lead, bis[carbonato(2-)]dihydroxytri-
Cresol
2,4-D, 2-butoxymethylethyl ester
Urea, (hydroxyethyl)-
DIMETHYL HEXYNOL
ETHYL-P-TOLUENESULFONAMIDE
ETHOXYPROPANOL BUTYL ETHER
Sodium naphthalene sulfonate
Benzene, diethenyl-
DIMETHYL OCTYNEDIOL
Methylnaphthalene
SODIUM PHENYLPHENATE
TETRAMETHYLDECANEDIOL
Sodium diisopropylnaphthalene sulfonate
Ethanol, 2-(octylphenoxy)-
Sodium decylbenzene sulfonate
SODIUM DI(2-ETHYLHEXYL) PYROPHOSPHATE
Glyceryl monoricinoleate
Propylene glycol monostearate
Glyceryl hydroxystearate
TRI-TERT-BUTYL-P-PHENYLPHENOL
Phenol, dinonyl-
C. I. Vat Orange 1
C.I. Vat Violet 1
C.I. Pigment Blue 61
C.I. Direct Yellow 1 1
C.I. Pigment Violet 3
C. I. Sulphur Black 1
Antimony oxide (unspecified)
Aluminum chloride hydroxide
Silicic acid, aluminum potassium salt
C.I. Sulphur Blue 7
C.I. Pigment Green 7
C.I. Direct Blue 86
Sodium tetraborate
2-Propenoic acid, isodecyl ester
2-Butenedioic acid (2Z)-, diisooctyl ester
Tricresyl phosphate
Hexanedioic acid, diisooctyl ester
1 ,2-Propanediol, monoacetate
Copper oxychloride (Cu2CI(OH)3)
Toluenesulfon amide
TETRAMETHYLDECYNEDIOL
Phenolsulfonic acid
Sodium bifluoride
Benzaldehyde, methyl-
Lead acetate
lonone, methyl-
Isocyclocitral
Ammonium hydroxide
SODIUM FRUCTOHEPTONATE
Methyl ethyl ketone peroxide
Sorbitan, monododecanoate
Sorbitan, monooctadecanoate
Sorbitan, mono-(9Z)-9-octadecenoate
Magnesium silicate
Nominated
































































































Draft
PCCL3









Yes












Yes
Yes








Yes








Yes












































Yes









Final
PCCL3









Yes












Yes
Yes








Yes








Yes












































Yes









Draft
CCL 3
































































































Public
Comment
































































































Final
CCL 3
































































































CCL 2
































































































CCL1
































































































        AS-33

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
1343982
1344009
1344010
1344032
1344098
1344281
1344372
1344430
1344816
1344952
1397940
1399800
1401690
1405921
1414455
1420048
1421632
1445756
1446613
1452159
1454859
1455772
1459105
1459934
1461229
1461252
1462846
1465254
1466768
1470946
1476115
1477425
1477550
1478611
1489696
1497683
1498517
1504741
1506021
1529573
1529584
1529595
1530489
1552427
1558334
1562001
1563388
1565942
1568805
1569013
1569024
1569693
1570645
1571080
1571331
1576358
1582098
1592230
1596845
1602977
1603403
1603414
1605181
1609478
1610180
1616882
1623069
1623149
1623241
1629589
1632162
1633052
1634022
1634044
1634782
1639607
1639663
1642542
1643205
1646759
1649087
1656480
1663394
1668548
1672464
1675543
1678917
1679647
1680213
1686142
1689823
1689845
1689992
1694093
1696179
1698608
Common Name
Silicic acid
Silicic acid, aluminum sodium salt
Silicic acid, aluminum calcium sodium salt
SODIUM CALCIUM SILICATE
Sodium silicate
Aluminum oxide
C.I. Pigment Yellow 34
Manganese oxide
Calcium polysulfide
Silicic acid, calcium salt
Antimycin A
Dodecyl p-tolyl trimethyl ammonium chloride
TYLOSIN
Cedrenol, acetate
Nisin
Clonitralid
1-Butanone, 1-(2,4,5-trihydroxyphenyl)-
Phosphonic acid, methyl-, bis(l-methylethyl) ester
Dehydroabietylamine
4-Thiazolecarbonitrile
1-Heptadecanol
1 H-1 ,2,4-Triazole-3,5-diamine
Benzene, tetradecyl-
1 ,3-Benzenedicarboxylic acid, dimethyl ester
Tributyltin chloride
Stannane, tetrabutyl-
2,3,6-Trimethylpyridine
N-(1-Naphthyl)ethylenediamine dihydrochloride
Benzole acid, 2,6-dimethoxy-
1H-lnden-5-d, 2,3-dihydro-
2-Butene, 1,4-dichloro-, (2Z)-
2-Benzothiazolamine, 4-methyl-
1 ,3-Benzenedimethanamine
4,4'-(Hexafluoroisopropylidene)diphenol
Cyclopropanecarboxaldehyde
Phosphonochloridothioic acid, ethyl-, O-ethyl ester
Phosphorodichloridic acid, ethyl ester
2-Propenal, 3-(2-methoxyphenyl)-
Acetyl hexamethyl tetralin
Aluminum, trieicosyl-
Aluminum, tritetradecyl-
Aluminum, tridodecyl-
Phosphonium, tributyl-2-propenyl-, chloride
1 (SH)-lsobenzofuranone, 6-(dimethylamino)-3,3-bis[4-
Silane, dichloro(chloromethyl)methyl-
Sodium isethionate
2,3-Dihydro-2,2-dimethyl-7-benzofuranol
Bisphenol A-glycidyl methacrylate
1,1'-Spirobi[1H-indene]-6,6'-diol, 2,2',3,3'-tetrahydro-3,3,31,31-
2-Propanol, 1-propoxy-
2-Propanol, 1-ethoxy-
Cyclohexanethiol
4-Chloro-2-methylphenol
Benzole acid, 4-formyl-, methyl ester
Phosphonic acid, phenyl-
4-Toluenesulfonyl hydrazide
Trifluralin
Calcium octadecanoate
Daminozide
HEXADECYL AMMONIUM CHLORIDE
2-Pyridinamine, 3-methyl-
2-Pyridinamine, 5-methyl-
Benzene, 1 ,4-bis(1-methylethenyl)-
Dicarbonic acid, diethyl ester
Prometon
Ethanol, 2-methoxy-, carbamate
Phosphoric acid, monopropyl ester
Phosphoric acid, monoethyl ester
Phosphoric acid, mono(l-methylethyl) ester
1-Penten-3-one
Heptane, 3-methylene-
Carbonic acid, strontium salt (1 :1)
Tetrabutylthiuram disulfide
Methyl tert-butyl ether
Malaoxon
Propoxyphene hydrochloride
Di-n-octyl sodium sulfosuccinate
Diethylcarbamazine citrate
1-Dodecanamine, N,N-dimethyl-, N-oxide
Propanal, 2-methyl-2-(methylthio)-, oxime
HCFC-132b
Propanenitrile, 3,3'-oxybis-
tert-Butyl acrylate
1 ,3,5-Triazin-2-amine, 4-methoxy-6-methyl-
digoxigenin
Bisphenol A diglycidyl ether
Cyclohexane, ethyl-
Hydrogen methyl terephthalate
Triethylene glycol diacrylate
3-Oxatricyclo[4.1 .1 .02,4]octane, 2,7,7-trimethyl-
Phenol, 4-(phenylazo)-
Bromoxynil
Bromoxynil octanoate
C.I. Acid Violet 49
Benzamide, N,N-diethyl-
Pyrazon
Nominated












Yes



















































Yes



















Yes






Yes




Draft
PCCL3
























Yes































Yes
Yes






Yes








Yes

Yes



















Yes
Final
PCCL3
























Yes































Yes
Yes






Yes








Yes

Yes



















Yes
Draft
CCL 3









































































Yes






















Public
Comment












Yes



















































Yes








Yes






















Final
CCL 3









































































Yes






















CCL 2
































































Yes








Yes






















CCL1
































































Yes








Yes






















        AS-34

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
1702176
1708298
1709702
1717006
1724396
1725015
1726654
1726665
1737935
1738256
1740198
1746038
1746776
1747600
1752303
1758732
1759531
1760243
1761713
1762261
1762272
1762283
1762954
1763231
1768316
1770805
1772254
1777840
1779255
1779482
1787617
1806264
1806297
1809149
1809194
1817681
1817738
1821029
1824813
1825214
1825623
1832548
1836222
1836755
1836777
1838080
1843034
1843056
1847581
1852148
1852160
1852171
1854268
1861321
1861401
1863634
1879090
1885149
1885296
1897456
1907331
1910425
1917153
1918009
1918167
1920054
1920907
1928434
1928456
1929733
1929777
1929824
1934210
1936158
1937195
1937377
1939362
1942718
1948330
1955459
1965293
1970407
1972083
1982372
1982474
1982496
1982690
1984061
2000433
2001947
2008391
2008415
2008584
2014837
2016560
2016571
Common Name
Clopyralid
Furan, 2,5-dihydro-
1,3,5-Trimethyl-2,4,6-tris(3,5-di-tert-butyl-4-
HCFC-141b
Cycled odecanol
1 ,8-Dioxacycloheptadecan-9-one
Aluminum, trihexadecyl-
Aluminum, tris(decyl)-
Pyridine, 3,5-dichloro-2,4,6-trifluoro-
Propanenitrile, 3-(dimethylamino)-
Dehydroabietic acid
Phosphonic acid, ethenyl-
Carbamic acid, 1-methylethyl ester
2-Benzothiazolamine, 6-methoxy-
Acetone thiosemicarbazide
Formamidine sulfinic acid
Cyclopropanecarboxylic acid
1 ,2-Ethanediamine, N-[3-(trimethoxysilyl)propyl]-
Cyclohexanamine, 4,4'-methylenebis-
Plumbane, ethyltrimethyl-
Plumbane, diethyldimethyl-
Plumbane, triethylmethyl-
Ammonium thiocyanate
Perfluorooctane sulfonic acid
1 ,1 ,1 ,3,3-Pentachloropropanone
Dibutyl chlorendate
1 ,3,6-Hexanetricarbonitrile
Acetamide, N-(4-ethoxy-3-nitrophenyl)-
Aluminum, chlorobis(2-methylpropyl)-
Phosphinic acid, phenyl-
C.l. Mordant Black 11, monosodium salt
Phenol, 4-octyl-
[1,1'-Biphenyl]-2,2'-diol
Phosphonic acid, dioctyl ester
Phosphonic acid, dibutyl ester
2,6-Bis(.alpha.-methylbenzyl)-p-cresol
Benzenamine, 2-bromo-4,6-dinitro-
2-Oxopentanoic acid
2-Pyridinamine, 6-methyl-
Benzene, pentachloromethoxy-
Silane, ethoxytrimethyl-
Phosphonic acid, methyl-, mono(l-methylethyl) ester
C.I. Pigment Red 60
Nitrofen
Benzene, 1 ,3,5-trichloro-2-(4-nitrophenoxy)-
1-Octadecanamine, hydrochloride
Topanol CA
Methanone, [2-hydroxy-4-(octyloxy)phenyl]phenyl-
Sodium lauryl sulfoacetate
Ethylenediurea
2-Propenamide, N-(butoxymethyl)-
2(1H)-Pyrimidinone, tetrahydro-
Dimethylol dihydroxyethyleneurea
Dacthal
Benfluralin
Ammonium benzoate
Phenol, 2-(1,1-dimethylethyl)-4,6-dimethyl-
Carbonochloridic acid, phenyl ester
Benzonitrile, 2-amino-
Chlorothalonil
2-Methyl-2-propanol, lithium salt
Paraquat dichloride
5-Methyl-2-furancarboxylic acid
Dicamba
Propachlor
N,N-Dimethyldodecylamine acetate
Plumbane, tetrabutyl-
2,4-D, 2-ethylhexyl ester
2,4-D, 3-butoxypropyl ester
2,4-D, 2-butoxyethyl ester
Vernolate
Nitrapyrin
Tartrazine
C.I. Acid Orange 10, disodium salt
Pimagedine hydrochloride
C.I. Direct Black 38
Glycine, N,N'-1 ,3-propanediylbis[N-(carboxymethyl)-
2-(p-tert-Butylphenoxy)cyclohexanol
2-tert-Butylhydroquinone
2-Oxetanone, 3,3-dimethyl-
Ethanol, 2-[[2-[(2-aminoethyl)amino]ethyl]amino]-
4-Pyridinol, 2,3,5-trichloro-
Dronabinol
Methdilazine
Chloroxuron
Siduron
Sodium dicamba
Sodium octanoate
Benzenemethanol, .alpha.-(trichloromethyl)-
Edetate dipotassium anhydrous
2,4-D, dimethylamine salt (1:1)
Butylate
2,6-Dichlorobenzamide
Trichlorotoluene, alpha 2,6-

1-Decanamine
Nominated























Yes



































Yes



Yes
































Draft
PCCL3











































Yes









Yes





Yes










Yes

Yes





Yes

















Final
PCCL3























Yes



















Yes









Yes





Yes










Yes

Yes





Yes

















Draft
CCL 3











































Yes




















































Public
Comment























Yes
Yes


















Yes




















































Final
CCL 3























Yes








































































CCL 2
































































































CCL1
































































































        AS-35

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
2027170
2031676
2032599
2032657
2033241
2038031
2044646
2049958
2050433
2050477
2050922
2051629
2051798
2052155
2052495
2058460
2074502
2077465
2078548
2082793
2082817
2094997
2104645
2104963
2114116
2131182
2136790
2141620
2152649
2155706
2155717
2156969
2162745
2163420
2163680
2164172
2176627
2179579
2185924
2197639
2210288
2210799
2212671
2216515
2219821
2223827
2223930
2226962
2231574
2235430
2235543
2238075
2243621
2244168
2244215
2253432
2257092
2273430
2274115
2300665
2303164
2303175
2304305
2310170
2312358
2321075
2338058
2349077
2349679
2350110
2353459
2358841
2363715
2365482
2372454
2374143
2385855
2386609
2386870
2399851
2402779
2402780
2402791
2403885
2409554
2416946
2420986
2425061
2425798
2425856
2426086
2426542
2429745
2429836
2431507
2432748
Common Name
2-lsopropylnaphthalene
Silane, triethoxymethyl-
Aminocarb
Methiocarb
Meldrum's acid
4-Morpholineethanamine
Butanamide, N,N-dimethyl-3-oxo-
Benzene, (1,1-dimethylpropyl)-
Acetamide, N-(2,4-dimethylphenyl)-
Benzene, 1,1'-oxybis[4-bromo-
1-Pentanamine, N-pentyl-
4-Chlorobiphenyl
4-Amino-3-methyl-N,N-diethylaniline hydrochloride
Pentanoic acid, 4-oxo-, butyl ester
Tetrabutylammonium hydroxide
Oxytetracycline hydrochloride
Paraquat methosulfate
2,3,6-Trichlorotoluene
Phenol, 2,6-bis(1-methylethyl)-
Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy
2-Propenoic acid, 2-methyl-, 1,4-butanediyl ester
m-Tetramethylxylene isocyanate
O-Ethyl O-(p-nitrophenyl) phenylphosphonothioate
Bromophos
Allylurethane
Benzene, pentadecyl-
Dacthal di-acid degradate
Propanenitrile, 3-ethoxy-
C.l. Solvent Blue 23, monohydrochloride
Tributyltin methacrylate
Di-t-butyl perphthalate
2-Propenoic acid, decyl ester
Bis(2,6-diisopropylphenyl)carbodiimide
1,3-Propanediol, 2-methyl-
2-Hydroxyatrazine
Fluometuron
Pyridine, pentachloro-
Diallyl disulfide
[1,1'-Biphenyl]-2-amine, hydrochloride
1-Hexadecanol, hydrogen phosphate
2-Propenoic acid, 2-methyl-, propyl ester
o-Cresyl glycidyl ether
Molinate
Levomenthol
Phenol, 2-(1, 1-dimethylethyl)-6-methyl-
2,2-Dimethyltrimethylene acrylate
Cadmium stearate
1-Piperidinyloxy, 4-hydroxy-2,2,6,6-tetramethyl-
Thiocarbazide
Pentasodium aminotrimethylene phosphonate
Ammonium lauryl sulfate
Diglycidyl ether
1 ,5-Naphthalenediamine
D-Carvone
Potassium dichloro-s-triazinetrione
Di-n-propylphosphorodithioic acid
Benzene, (2-isothiocyanatoethyl)-
Stannane, butylhydroxyoxo-
2-Propenoic acid, 1,2-ethanediyl ester
Dimethylamine dicamba
Diallate
Triallate
Phosphonium, tetrabutyl-, chloride
Phosalone
Propargite
Fluorescein
Ferric citrate
Propanoic acid, 2-methyl-, hexyl ester
1 ,3,4-Thiadiazole-2(3H)-thione, 5-amino-
Dodecane, 2-chloro-
C.l. Food Green 3, disodium salt
Diethylene glycol bis(methacrylate)
Heneicosanoic acid
Methyl thioglycolate
1-Butanol, sodium salt
1 ,3,5-Tris(trifluoropropyl)trimethylcyclotrisiloxane
Mirex
1-Butanesulfonyl chloride
7-Oxabicyclo[4.1.0]heptane-3-carboxylic acid, 7-
Glycine, N,N-bis(carboxymethyl)-, tripotassium salt
2,3-DICHLORO PYRIDINE
2,6-Dichloropyridine
2,3,5,6-Tetrachloropyridine
Lastar A
2-tert-Butyl-p-cresol
Phenol, 2,3,6-trimethyl-
Hexanoic acid, 2-ethyl-, cadmium salt
Captafol
Oxirane, 2,2'-[1 ,4-butanediylbis(oxymethylene)]bis-
C.l. Pigment Red 3
Oxirane, (butoxymethyl)-
2-Propenoic acid, 2-(diethylamino)ethyl ester
C.I. Direct Blue 15
C.I. Direct Black 4, disodium salt
1-Butene, 2,3,4-trichloro-
Hexanenitrile, 6-amino-
Nominated


































Yes
Yes




























































Draft
PCCL3



































Yes
Yes





Yes





Yes















Yes



























Yes



Final
PCCL3



































Yes
Yes





Yes





Yes















Yes



























Yes



Draft
CCL 3










































Yes





















































Public
Comment












































































Yes



















Final
CCL 3










































Yes





















































CCL 2


























Yes















Yes





















































CCL1


























Yes















Yes





















































        AS-36

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
2432997
2437254
2437561
2438882
2439012
2439103
2439352
2440224
2444191
2444464
2444908
2451629
2455245
2459101
2461156
2461189
2465272
2469558
2475312
2475458
2475469
2479461
2487903
2489772
2492264
2495252
2495274
2495398
2497065
2497076
2497214
2498660
2499958
2503562
2512290
2516338
2516407
2524030
2524041
2528361
2530838
2530850
2530872
2538854
2540547
2549511
2549533
2549679
2550267
2550405
2551624
2554065
2579206
2580781
2587760
2588036
2588047
2591868
2593159
2597037
2600693
2602462
2605449
2608482
2610051
2610119
2611009
2611827
2622211
2623236
2627954
2628162
2634335
2638940
2641341
2642719
2648568
2648579
2648615
2650182
2654582
2664633
2666140
2675776
2680037
2682204
2687254
2687914
2687947
2687969
2691410
2694544
2696926
2698411
2699798
2702729
Common Name
1 1-Aminoundecanoic acid
Dodecanenitrile
1-Tridecene
Benzene, 1 ,2,4,5-tetrachloro-3-methoxy-6-nitro-
Chinomethionate
Dodine
2-(Dimethylamino)ethyl aciylate
2-(2H-Benzotriazol-2-yl)-p-cresol
P-BENZOXYPHENOL
N-Vanillylnonan amide
Phenol, 4,4'-(1-methylethylidene)bis-, disodium salt
Triglycidyl isocyanurate
Tetrahydrofurfuryl methacrylate
1 ,2,4-Benzenetricarboxylic acid, trimethyl ester
Oxirane, [[(2-ethylhexyl)oxy]methyl]-
Oxirane, [(dodecyloxy)methyl]-
Auramine, monohydrochloride
Bis(3-aminopropyl)tetramethyl disiloxane
Tetrabromoindigo
C.I. Disperse Blue 1
C.I. Disperse Blue 3
Benzenamine, 4,4'-[1 ,3-phenylenebis(oxy)]bis-
Silane, trimethoxy-
Thiourea, trimethyl-
Sodium mercaptobenzothiazole
2-Propenoic acid, 2-methyl-, tridecyl ester
2-Propenoic acid, 2-methyl-, hexadecyl ester
2-Propene-1-sulfonic acid, sodium salt
Disyston sulfone
Oxydisulfoton
4-Hexen-3-one
7,12-Benz(a)anthraquinone
2-Propenoic acid, hexyl ester
[1 ,2,4]Triazolo[1 ,5-a]pyrimidin-7-ol, 5-methyl-
C.l. Pigment Yellow 1
Cyclopropanemethanol
2-Bromobenzothiazole
Dimethyl chlorothiophosphate
Phosphorochloridothioic acid, O,O-diethyl ester
Phosphoric acid, dibutyl phenyl ester
Silane, trimethoxy[3-(oxiranylmethoxy)propyl]-
3-(Trimethoxysilyl)propyl methacrylate
Silane, (3-chloropropyl)trimethoxy-
Calcon
GLYCEROL TRIRICINOLEATE
Acetic acid, chloro-, ethenyl ester
2-Propenoic acid, 2-methyl-, tetradecyl ester
Aziridine, 2-ethyl-
2-Butanone, 4-phenyl-
Disulfide, dicyclohexyl
Sulfur fluoride (SF6), (OC-6-11)-
Tetravinyltetramethylcyclotetrasiloxane
1 ,3-Cyclohexanedimethanamine
C.I. Reactive Blue 19
Stannane, chlorotrioctyl-
Phorate sulfoxide
Phorate sulfone
1-Piperidinecarboxaldehyde
Etridiazole
Phenthoate
Phorate oxon
Direct Blue 6
Dodecanoic acid, cadmium salt
2,4-Pentadienal, 5-(4-nitrophenyl)-
C.l. Direct Blue 1, tetrasodium salt
C.I. Direct Red 81, disodium salt
3-Cyclohexenyl 3-cyclohexene 1-carboxylate
C.I. Acid Red 18, trisodium salt
Cyclohexene, 1-ethenyl-
l-Menthyl acetate
Disiloxane, 1 ,3-diethenyl-1 ,1 ,3,3-tetramethyl-
Phenol, 4-ethenyl-, acetate
1 ,2-Benzisothiazolin-3-one
Hexafluoropropene oxide trimer
Hexafluoropropene oxide trimer
Azinphos-ethyl
1 ,1-Dichloro-2-butanone
3,3-Dichloro-2-butanone
Ethanone, 2,2-dichloro-1-phenyl-
C.l. Acid Blue 9, diammonium salt
Dimezone
Phenol, 4,4'-thiobis-
Trisodium etidronate
Chloroneb
2-Propenamide, N,N-dimethyl-
2-Methyl-3(2H)-isothiazolone
1 ,2-Benzenediamine, 3-methyl-
2-Pyrrolidinone, 1-ethyl-
2-Pyrrolidinone, 1-octyl-
2-Pyrrolidinone, 1-dodecyl-
HMX
1 ,2,4-Triallyl trimellitate
Nitrosyl chloride ((NO)CI)
Propanedinitrile, [(2-chlorophenyl)methylene]-
Sulfuryl fluoride
2,4-D, sodium salt
Nominated
































































































Draft
PCCL3
Yes




Yes
Yes



















































































Yes



Yes

Final
PCCL3
Yes




Yes
Yes



















































































Yes



Yes

Draft
CCL 3
































































































Public
Comment
































































































Final
CCL 3
































































































CCL 2
































































































CCL1
































































































        A5-37

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
2705875
2706287
2716101
2720732
2725226
2735048
2738069
2756878
2757280
2757906
2764729
2768027
2778429
2781104
2781115
2782572
2783177
2783940
2784943
2785877
2786767
2801685
2807309
2808868
2809214
2814202
2814779
2825823
2832191
2832408
2835394
2835952
2836320
2837890
2855132
2855198
2859678
2861021
2866435
2867472
2868373
2869343
2871014
2873974
2893789
2896700
2905626
2905659
2915539
2917739
2921882
2935902
2937500
2941642
2943751
2948461
2971224
2978587
2991517
2996921
2997924
3001614
3006153
3006937
3010820
3012655
3018120
3026639
3027212
3030475
3031661
3032551
3033623
3033770
3048644
3048655
3049716
3052504
3056937
3064708
3068006
3076048
3076639
3081014
3081149
3084488
3085301
3087169
3088311
3089110
3089165
3091256
3101608
3118976
3120749
3129917
Common Name
Cyclohexanepropanoic acid, 2-propenyl ester
Acid yellow 9
Bisaniline P
Carbonodithioic acid, O-pentyl ester, potassium salt
Phenol, 2-[4,6-bis(2,4-dimethylphenyl)-1 ,3,5-triazin-2-yl]-5-
Benzenamine, 2,4-dimethoxy-
2-Butanamine, N-ethyl-3-methyl-
MONOMETHYL FUMARATE
1-Heptanamine, 6-methyl-N,N-bis(6-methylheptyl)-
Agaritine
Diquat
Silane, ethenyltrimethoxy-
Benzene, 1 ,3-bis(1-isocyanato-1-methylethyl)-
Stannane, dibutylbis[(2-ethyl-1-oxohexyl)oxy]-
Diethyl (diethanolamino)methylphosphonate
Dichloro-s-triazinetrione
1,12-Dodecanediamine
C.I. Food Yellow 3
HC Blue No. 1
Phenol, 2-methoxy-4-propyl-
C.l. Pigment Red 170
Benzeneethanamine, 2,5-dimethoxy-.alpha.-methyl-
Ethylene glycol monopropyl ether
2,3,4,5-Tetrachloropyridine
Phosphonic acid, (l-hydroxyethylidene)bis-
6-Methyl-2-(1-methylethyl)-4(1H)-pyrimidinone
C.I. Pigment Red 4
exo-Trimethylenenorbornane
2-Chloro-N-(hydroxymethyl)acetamide
C.I. Disperse Yellow 3
Butanoic acid, 3-methyl-, 2-propenyl ester
Phenol, 5-amino-2-methyl-
Sodium glycolate
HCFC-124
Cyclohexanemethanamine, 5-amino-1 ,3,3-trimethyl-
Oxirane, decyl-
3-Pyridinepropanol
Alizarine sapphire
Benzoxazole, 2,2'-(2,5-thiophenediyl)bis-
2-(Dimethylamino)ethyl methacrylate
Cyclopropanecarboxylic acid, methyl ester
1-Tridecanamine
Ethanol, 2-[(4-amino-2-nitrophenyl)amino]-
2-Propenamide, N-(1 ,1-dimethyl-3-oxobutyl)-
Sodium dichloro-s-triazinetrione
Triacetoneamine-N-oxyl
Benzoyl chloride, 3,5-dichloro-
Benzoic acid, 3-chloro-, methyl ester
2-Butenedioic acid (2Z)-, dioctyl ester
Nonanedioic acid, dibutyl ester
Chlorpyrifos
Propanoic acid, 3-mercapto-, methyl ester
Carbonochloridic acid, 2-propenyl ester
Carbonochloridothioic acid, S-ethyl ester
Silane, triethoxyoctyl-
p-Bis(2-hydroxyisopropyl)benzene
Benzene, 1,1'-(2,2,2-trichloroethylidene)bis-
3-Butyn-2-amine, 2-methyl-
Glycine, N-ethyl-N-[(heptadecafluorooctyl)sulfonyl]-,
Silane, trimethoxyphenyl-
2,2'-Azobis(2-amidinopropane) dihydrochloride
Dihydroxydi(methoxymethyl)ethyleneurea
Sodium 1,4-dihexyl sulfosuccinate
1H-Pyrrole-2,5-dione, 1,1'-(1,3-phenylene)bis-
1 ,4-Benzenedicarboxamide
Diammonium citrate
Dichloroacetonitrile (DCAN)
1-Tridecanol, hydrogen sulfate, sodium salt
Silane, dimethoxymethylphenyl-
N,N',N"-Pentamethyldiethylenetriamine
3-Hexyne-2,5-diol
1 ,1 ,1-Trimethylolethane trinitrate
Ethanamine, 2,2'-oxybis[N,N-dimethyl-
Oxiranemethanaminium, N,N,N-trimethyl-, chloride
5-Vinyl-2-Norbornene
1H-lndene, 3a,4,7,7a-tetrahydro-
C.l. Pigment Red 178
2-Butenedioic acid (2Z)-, monomethyl ester
C.I. Basic Orange 21
Bis(trichloromethyl) sulfone
1,2,4-Butanetriol
2-Propenoic acid, tridecyl ester
Tridodecyl phosphite
Santoflex 1 4
1 ,4-Benzenediamine, N,N'-bis(1 ,4-dimethylpentyl)-
Phosphine oxide, trihexyl-
1-Butanol, aluminum salt
C.I. Acid Green 50
Sodium laureth sulfate
Hexakis(methoxymethyl)melamine
Quinacridone, 4,11-dichloro-
Stannane, trichlorooctyl-
Oxirane, [[4-(1 ,1-dimethylethyl)phenoxy]methyl]-
C.l. Solvent Orange 7
4-(Methylthio)-m-cresol
Cyclohexanamine, N-cyclohexyl-, nitrite
Nominated


















































Yes













































Draft
PCCL3










Yes


















Yes


































































Final
PCCL3










Yes


















Yes




































Yes





























Draft
CCL 3
































































































Public
Comment


















































Yes















Yes





























Final
CCL 3
































































































CCL 2
































































































CCL1
































































































        AS-38

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
3130196
3132998
3147759
3148729
3164292
3165933
3173533
3173726
3177228
3179768
3179906
3194556
3195786
3209221
3223072
3234024
3234853
3251238
3252435
3268493
3271054
3273243
3277267
3290708
3290924
3296900
3319311
3322938
3327228
3330152
3337711
3338247
3380345
3383968
3385215
3385419
3388043
3397624
3401807
3424826
3425614
3440753
3441143
3445112
3452979
3458228
3468119
3468631
3486359
3497005
3520421
3520727
3524683
3542367
3546109
3564098
3567257
3567666
3567699
3586149
3590849
3604873
3618722
3622842
3632915
3634831
3647696
3648188
3648202
3648213
3653483
3655003
3658488
3658773
3681718
3689245
3710847
3720976
3724650
3734483
3734676
3735339
3737415
3748138
3758541
3761419
3770976
3775904
3778732
3785340
3794830
3796701
3806346
3810740
3811732
3844459
Common Name
Bis((3,4-epoxycyclohexyl)methyl) adipate
Benzaldehyde, 3-bromo-
Octrizole
1 ,3-Diaminopropanol tetraacetic acid
Diammoniumtartrate
4-Chloro-o-toluidine hydrochloride
Cyclohexane, isocyanato-
1 ,5-Naphthalene diisocyanate
Sodium 2,4-diaminobenzenesulfonate
1-Propanamine, 3-(diethoxymethylsilyl)-
C.l. Disperse Blue 7
Cyclododecane, 1 ,2,5,6,9,10-hexabromo-
Acetamide, N-ethenyl-N-metriyl-
Benzene, 1,2-dichloro-3-nitro-
Melphalan
2-Butene-1,4-diol, 2,3-dibromo-
Tetradecanoic acid, tetradecyl ester
Cupric nitrate
Dibromoacetonitrile (DBAN)
Methional
N- Methyl- 4-methoxynaphthalimide
DI(2-HYDROXY-5-TERT-BUTYLPHENYL)SULFIDE
Disiloxane, 1,1,3,3-tetramethyl-
1-Butanol, 2,4,4,4-tetrachloro-
Trimethylolpropanetrimethacrylate
Pentaerythritol dibromide
Tris(2-ethylhexyl) trimellitate
Cyclohexane, 1 ,2-dibromo-4-(1 ,2-dibromoethyl)-
Dextrosil
Ether, heptafluoropropyl 1 ,2,2,2-tetrafluoroethyl
Asulam
Sodium diethyl phosphorodithioate
Triclosan
Temephos
1 ,3-Cyclohexanediamine
Hexanedioic acid, diammonium salt
((Epoxycyclohexyl)ethyl)trimethoxy silane
2-Chloro-4,6-diamino-s-triazine
3,6-Dichlorosalicylic acid
o,p'-DDE
Hydroperoxide, 1,1-dimethylpropyl
Plumbane, tetrapropyl-
C.l. Direct Red 23, disodium salt
2-Pyrrolidinone, 1-(2-hydroxyethyl)-
3,5,5-Trimethyl-1-hexanol
Improsulfan hydrochloride
Phthalogen
C.I. Pigment Orange 5
Zinc carbonate
Phosphonothioic dichloride, phenyl-
C.l. Acid Red 52
C.I. Pigment Orange 13
Pentaerythrityl triacrylate
Stannane, dichlorodioctyl-
Phenesterin
C.I. Food Red 6, disodium salt
Sulcofuron-sodium
C.I. Acid Red 33, disodium salt
C.I. Acid Red 14, disodium salt
Benzene, 1-methyl-3-phenoxy-
Stannane, tetraoctyl-
alpha-Ecdysone
C.I. Disperse Blue 79:1
Benzenesulfonamide, N-butyl-
Magnesium gluconate
Benzene, 1 ,3-bis(isocyanatomethyl)-
Morpholine, 4-(2-chloroethyl)-, hydrochloride
Stannane, dioctylbis[(1-oxododecyl)oxy]-
Diundecyl phthalate
Diheptyl phthalate
Methoxone sodium salt
Disodium lauriminodipropionate
Diisooctyl phosphite
4-Hydroxy-2,5-dimethyl-3(2H)furanone
3-Hexen-1-ol, acetate, (3Z)-
Sulfotep
Ethanamine, N-ethyl-N-hydroxy-
2-lmidazolidinone, 4,5-dihydroxy-
Crotonic acid
Chlordene
C. I. Food Red 10
Phosmet oxon
3,3,4,4-Tetrachlorotetrahydrothiophene 1,1 -dioxide
Benzene, 1 ,3-bis(1-methylethenyl)-
Catanac SP Antistatic Agent
Fenthion sulfoxide
2-Diazo-1-naphthol-5-sulfonyl chloride
2-(tert-Butylamino)ethyl methacrylate
Ifosfamide
1 ,2-BIS(MONOBROMOACETOXY)ETHANE
Tetrasodium etidronate
5,9-Undecadien-2-one, 6,10-dimethyl-, (5E)-
O,O'-Dioctadecylpentaerythritol bis(phosphite)
Streptomycin sulfate
2-Pyridinethiol, 1-oxide, sodium salt
C.I. Acid Blue 9, disodium salt
Nominated
































Yes




Yes


























































Draft
PCCL3



















Yes





Yes












Yes

























































Final
PCCL3


















Yes
Yes





Yes












Yes

























































Draft
CCL 3
































































































Public
Comment


















Yes













Yes























































Yes







Final
CCL 3
































































































CCL 2
































































































CCL1
































































































        AS-39

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
3846717
3852093
3864991
3896115
3900047
3926623
3944727
3965557
3982910
3990032
3991739
4028324
4035896
4041092
4051632
4065456
4066028
4074888
4075814
4080313
4083641
4097476
4098719
4109960
4118165
4151502
4169044
4170303
4180238
4193559
4196865
4196876
4196898
4197255
4208804
4220524
4221685
4223034
4246519
4253229
4253343
4259158
4297954
4320303
4337660
4342034
4342363
4345033
4346514
4353280
4368563
4374463
4378614
4390049
4394858
4403901
4418262
4418615
4420740
4424060
4432319
4435534
4437858
4454051
4461523
4465945
4468024
4471470
4474242
4475950
4485125
4499018
4499869
4505548
4525331
4548532
4549400
4553622
4559868
4574043
4584467
4584490
4602840
4621049
4635590
4635874
4638033
4680788
4684940
4685147
4691650
4702641
4719044
4726141
4736601
4744472
Common Name
2-Benzotriazol-2-yl-4,6-di-tert-butylphenol
Propanoic acid, 3-methoxy-, methyl ester
2,4-Di-tert-butyl-6-(5-chlorobenzotriazol-2-yl)phenol
Bumetrizole
Phosphoric acid, monohexyl ester
Sodium chloroacetate
1-OCTANESULFONICACID
Sodium dimethyl 5-sulphonatoisophthalate
Phosphorothioic trichloride
2-Butenedioic acid (2Z)-, monoethyl ester
Phosphoric acid, monooctyl ester
Benzenesulfonic acid, 2,2'-(1,2-ethenediyl)bis[5-[[4-[bis(2-
Tris(6-isocyanatohexyl) biuret
2,5-Dimethylcyclopentanone
[1,1'-Bianthracene]-9,9',10,10'-tetrone, 4,4'-diamino-
Sulisobenzone
Phenol, 2,2'-methylenebis[6-cyclohexyl-4-methyl-
2-Propenoic acid, oxydi-2,1-ethanediyl ester
Calcium propionate
N-(3-Chloroallyl)hexaminium chloride
Benzenesulfonyl isocyanate, 4-methyl-
Phenol,4-(1-methylethyl)-2,6-dinitro-
Isophorone diisocyanate
Dichlorosilane
9,10-Anthracenedione, 1,1'-[(6-phenyl-1,3,5-triazine-2,4-
Sulfluramid
1-Propanol, 2-phenoxy-
Crot on aldehyde
Benzene, 1-methoxy-4-(1 E)-1-propenyl-
Cellufluor
Pentaerythritol tetrabenzoate
Trimethylolethyl tribenzoate
1,3-Propanediol, 2,2-dimethyl-, dibenzoate
C.I. Solvent Black 3
C.I. Basic Yellow 11
3-Methyl-2,4-hexanedione
4,4'-CYCLOHEXYLIDENEBIS(2-CYCLOHEXYLPHENOL)
2-Propenamide, N-(1 ,1 ,3,3-tetramethylbutyl)-
1-Propanamine, 3,3'-[oxybis(2,1-ethanediyloxy)]bis-
Stannane, dibutylthioxo-
Silanetriol, methyl-, triacetate
Phosphorodithioic acid, O,O-di-2-ethylhexyl ester, zinc salt
Sodium phenylphosphinate
L-Glutamic acid, compd. with L-arginine (1:1)
Ethanol, 2-amino-, benzoate (salt)
Dacarbazine
Tributyltin benzoate
Vitamin E succinate
p-Nitroaniline-2-sulfonic acid, ammonium salt
3,6,9,1 2,1 5-Pentaoxaheptadecane
C.I. Acid Blue 62
Dioxobutanoic acid
Pigment Red 168
Isohexadecane
4-Morpholinecarboxaldehyde
C.I. Acid Green 25
3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione sodium
1 H-Tetrazol-5-amine
1-Propanethiol, 3-(trimethoxysilyl)-
C.l. Pigment Orange 43
4-Morpholineethanesulfonic acid
1-Butanol, 3-methoxy-, acetate
1,3-Dioxolan-2-one, 4-ethyl-
2H-Pyran, 3,4-dihydro-2-methoxy-
Methanol, methoxy-
Cytoxyl alcohol cyclohexylammonium salt
Zinc, bis(D-gluconato-. kappa. O1,. kappa. O2)-, (T-4)-
Cyanoformaldehyde
C.I. Acid Blue 80
Butanenitrile, 2-amino- 2-methyl-
Lithium stearate
Procion Brilliant Blue M-RS
1-Propanaminium, N,N,N-tripropyl-, hydroxide
3-Methyl-1,2,4-cyclopentanetrione
Dicarbonic acid, dimethyl ester
C.I. Food Red 1, disodium salt
N-Nitrosomethylvinylamine
Methylglutaronitrile
Urea, tetrabutyl-
1-Tetradecanaminium, N,N,N-trimethyl-, chloride
(2-Chloroethyl)dimethylamine, hydrochloride
2-Chloropropyl-dimethylamine hydrochloride
Farnesol
Cyclohexanol, 4-(1-methylethyl)-
Butanoyl chloride, 4-chloro-
3-Pentenenitrile
2-Propanol, 1-chloro-3-(2-propenyloxy)-
C. I. Acid Green 3
2-Pyridinecarboxylic acid, 6-chloro-
Paraquat
Disodium inosinate
2-(4'-Methoxyphenyl)-4,8-diaminoanthrarufin
Hexahydro-1,3,5-tris(2-hydroxyethyl)-s-triazine
Nitralin
Phosphonium, ethyltriphenyl-, iodide
2H-Pyran-3,3,5,5(4H,6H)-tetramethanol,4-hydroxy-
Nominated
































































































Draft
PCCL3





Yes







































































Yes











Yes


Yes



Final
PCCL3





Yes







































































Yes











Yes


Yes



Draft
CCL 3
































































































Public
Comment



































































Yes




























Final
CCL 3
































































































CCL 2
































































































CCL1
































































































        AS-40

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
4749273
4767037
4771088
4835114
4856955
4901513
4904614
4940118
4948156
4948281
4979322
5022297
5039781
5042546
5064313
5089769
5102830
5103719
5103742
5123637
5124254
5124301
5131602
5131668
5137553
5141208
5160021
5216251
5224237
5232995
5234684
5259881
5278955
5280808
5281049
5283669
5307142
5323955
5329146
5331328
5331431
5331771
5332730
5344274
5352885
5392405
5394365
5397319
5397342
5401945
5406973
5407045
5407874
5419556
5421465
5434571
5436215
5437332
5437456
5437989
5459938
5460093
5462066
5468439
5468757
5471512
5490277
5493458
5496106
5510996
5521313
5522430
5567157
5589968
5593704
5598130
5610640
5634399
5700492
5716154
5743271
5766676
5810117
5810888
5847552
5858811
5888335
5892104
5902512
5905522
5910758
5910792
5915413
5917613
5964352
5967099
Common Name
3,3,3-Trichloro-2-methyl-1-propene
Dimethylolpropionic acid
Benzamide, N-(S-nitrophenyl)-
N,N'-Dibutyl-1 ,6-hexanediamine
Boron, trihydro(morpholine-. kappa. N4)-, (T-4)-
2,3,4,5-Tetrachlorophenol
1 ,5,9-Cyclododecatriene
4H-Pyran-4-one, 2-ethyl-3-hydroxy-
C.l. Pigment Red 149
cis-2-Pinanol
2-Benzothiazolesulfenamide, N,N-dicyclohexyl-
1 H-lsoindole-1 ,3(2H)-dione, 2-ethyl-
(2-(Methacryloyloxy)ethyl)trimethylammonium chloride
1 ,3-Benzenediamine, 4-methyl-6-(phenylazo)-
Nitrilotriacetic acid trisodium salt
Tetra-sec-butoxysilane
C.I. Pigment Yellow 13
cis-Chlordane
trans-Chlordane
Sodium N,N-diethylmetanilate
C.I. Disperse Yellow 42
1 ,1-Methylene bis(4-isocyanatocyclohexane)
1,3-Benzenediamine, 4-chloro-
2-Propanol, 1-butoxy-
1-Octanaminium, N-methyl-N,N-dioctyl-, chloride
C.I. Acid Green 5, disodium salt
C.I. Pigment Red 53, barium salt (2:1)
4-Chlorobenzotrichloride
Triethyl Lead
Etocrylene
Carboxin
Oxycarboxin
Chlorodibromoacetic Acid (CDBAA)
Benzamide, 3,3'-[(2,5-dimethyl-1 ,4-phenylene)bis[imino(1-
C.l. Pigment Red 57, calcium salt (1:1)
Silane, trichlorooctyl-
1,4-Benzenediamine, 2-nitro-
Sodium ricinoleate
Sulfamic acid
Isoborneol methyl ether
Benzyloxycarbonyl hydrazide
Docosanoic acid, sodium salt
1-Propanamine, 3-methoxy-
4-Pyridineethanol
N-(4-Chlorophenyl)-N'-methylurea
Citral
2,4-lmidazolidinedione,5-ethyl-5-methyl-
1-Propanamine, 3-[(2-ethylhexyl)oxy]-
Phenol, 2-[(4-hydroxyphenyl)sulfonyl]-
1 H-lndazole, 5-nitro-
Pyridinium, 1-dodecyl-, salt with 5-chloro-2(3H)-
Dimethylaminopropyl chloride, hydrochloride
2-Pyridinamine, 4,6-dimethyl-
Boric acid (H3BO3), tris(l-methylethyl) ester
Acetic acid, mercapto-, monoammonium salt
Propanoic acid, 2,2-dimethyl-, hexyl ester
2-Butanone, 4,4-dimethoxy-
2(1H)-Pyridinone, 3,5-dichloro-
Benzyl bromoacetate
p-Acetoacetanisidine
Cyclohexanamine, N-ethyl-
Ash acid
Benzenepropanal, 4-methoxy-.alpha.-methyl-
2-Mecaptobenzothiazole 1-(2-hydroxyethyl)pyridinium salt
C.I. Pigment Yellow 14
2-Butanone, 4-(4-hydroxyphenyl)-
Dihydrostreptomycin Sulfate
Diglycidyl hexahydrophthalate
Cyclohexanecarbonitrile, 1-amino-
Phenol, 2,6-bis(1-methylpropyl)-
C.l. Pigment Red 179
1-Nitropyrene
C.I. Pigment Yellow 83
Bromochloroacetic Acid (BCAA)
1-Butanol,titanium(4+)salt
Ch lorpyr if os-methyl
C.I. Acid Black 52
1 ,3-Dioxolane-4-methanol, 2-(1-iodoethyl)-
Ethylenediamine dihydroiodide
Maleic hydrazide diethanolamine salt
L-Ascorbic acid, calcium salt (2:1)
Ethylenediaminetetraacetonitrile
Butanamide, 2-chloro-N,N-dimethyl-3-oxo-
Bis(2-ethylhexyl) phosphorodithioate
Stannane, dibutylbis[(1-oxooctadecyl)oxy]-
C.l. Pigment Red 57, disodium salt
Isobornyl acrylate
2,4-Dioxa-1 ,5-dibismapentane, 1 ,3,5-trioxo-
Terbacil
Propanoic acid, 2-hydroxy-, iron(2+) salt (2:1)
1-Tridecanamine, N-tridecyl-
1-Heptadecanol, hydrogen sulfate, sodium salt
Terbuthylazine
Propane, 1,1'-[methylenebis(oxy)]bis[2,2-dinitro-
EDTA tetrapotassium salt
Distannoxane, 1 ,3-bis(acetyloxy)-1 ,1 ,3,3-tetrabutyl-
Nominated
































Yes








































Yes






















Draft
PCCL3






Yes



















Yes
Yes




































































Final
PCCL3






Yes



















Yes
Yes




































































Draft
CCL 3
































































































Public
Comment
































Yes








































Yes






















Final
CCL 3
































































































CCL 2
























































































Yes







CCL1
























































































Yes







        A5-41

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
5977140
5979282
5989275
5989548
6000448
6055192
6055523
6075112
6087565
6099576
6104309
6108107
6109973
6117915
6144043
6145739
6175457
6190654
6197304
6219892
6259763
6262426
6272748
6274277
6283256
6285570
6291845
6294344
6294899
6317186
6320145
6358072
6358094
6358312
6358538
6358641
6358696
6358856
6362794
6369591
6373746
6375559
6381777
6386385
6406560
6410102
6413101
6416688
6419198
6422839
6422862
6423434
6428315
6440580
6448959
6459945
6471494
6483643
6485343
6485398
6485401
6505288
6533682
6542376
6600313
6610293
6618037
6632684
6683198
6711484
6728263
6731368
6737242
6742547
6789884
6804075
6834920
6837247
6842155
6843669
6846500
6863587
6864375
6865356
6891447
6893023
6915157
6938949
6959473
6959484
6969499
6990438
7005472
7005723
7008426
7027114
Common Name
Butanamide, 3-oxo-
C.l. Pigment Yellow 16
(d)-Limonene
Cyclohexene, 1-methyl-4-(1-methylethenyl)-, (4S)-
Sodium glycinate
Cyclophosph amide
1 ,6-Hexanediamine, dihydrochloride
3-Pentanone, 1 ,5-di-2-furanyl-
4-Diazo-N,N-dimethylanilin chlorozincate
Sodium 4-hydroxynaphthalene-1-sulphonate
Urea, N,N"-(2-methylpropylidene)bis-
epsilon-HCH
3-Amino-9-ethylcarbazole hydrochloride
2-Buten-1-ol
Benzene, (1-methylethenyl)-, dimer
1-Propanol, 2-chloro-, phosphate (3:1)
Ethanone, 2,2-diethoxy-1-phenyl-
Desethylatrazine
Octocrylene
Phenol, 4-[(4-amino-3-methylphenyl)amino]-
Benzoic acid, 2-hydroxy-, hexyl ester
Tetrachlorocyclopropene
Lapyrium chloride
Acetic acid, [(2,5-dichlorophenyl)thio]-
Benzenamine, 2-chloro- 5-nitro-
2-Benzothiazolamine, 6-nitro-
1,3-Propanediamine, N-methyl-
Bis(2-chloroethyl) 2-chloroethylphosphonate
Hydrazinecarboxylic acid, methyl ester
Methylene dithiocyanate
C.I. Basic Red 12
Phenol, 2-amino-4-chloro-5-nitro-
Phenol, 2-amino-6-chloro-4-nitro-
C.l. Pigment Yellow 74
Citrus Red No. 2
Benzenamine, 4-chloro-2,5-dimethoxy-
C.l. Solvent Green 7
C.I. Pigment Yellow 12
Sodium hydrogen-5-sulphoisophthalate
1 ,4-Benzenediamine, 2-methyl-, sulfate
C.I. Acid Orange 3
C.I. Acid Yellow 42, disodium salt
Sodium erythorbate
Hydrocinnamic acid, 3,5-di-tert-butyl-4-hydroxy-, methyl ester
C.I. Acid Red 151, monosodium salt
C.I. Pigment Red 1
1 ,3-Dioxolane-2-acetic acid, 2-methyl-, ethyl ester
C.I. Fluorescent Brightener46
Phosphonic acid, [nitrilotris(methylene)]tris-
2,4-Bismaleimidotoluene
Bis(2-ethylhexyl) terephthalate
1 ,2-Propanediol, dinitrate
C.I. Direct Black 19, disodium salt
1 ,3-Dimethylol-5,5-dimethylhydantoin
C.I. Pigment Red 22
C.I. Acid Red 11 4, disodium salt
C.I. Pigment Red 23
2-Naphthalenol, 1,1'-[(phenylmethylene)bis[(2-methoxy-4,1-
Saccharin calcium anhydrous
MANGANESE GLUCONATE
(-)-Carvone
Butanamide, 2,2'-[(3,3'-dimethoxy[1 ,1 '-biphenyl]-4,4'-
Scopolamine Hydrobromide
Hydroxymethyl dioxoazabicyclooctane
Bis(delta-tetrahydrobenzylidene)pentaerythritol
4-Methyl-3-thiosemicarbazide
Tripropyl Lead
1 ,3-Dimethyl-4-amino-5-nitrosouracil
Irganox 1010
1 ,3-Propanediamine, N'-[3-(dimethylamino)propyl]-N,N-
2-Hexenal, (2E)-
Trigonox 29
Acetic acid, hydroxy[(1-oxo-2-propenyl)amino]-
Benzene, undecyl-
Benzoic acid, hexyl ester
CARBADOX
Sodium metasilicate
2-Pyrrolidinone, 1-cyclohexyl-
1-Propene, tetramer
Silane, dimethoxydiphenyl-
Kodaflex txib
Butane, 2,2'-oxybis-
Cyclohexanamine, 4,4'-methylenebis[2-methyl-
Octadecanoic acid, barium salt
Ethanaminium, N,N,N-trimethyl-2-[(2-methyl-1-oxo-2-
LIOTHYRONINE
Malic acid
Diisopropyl adipate
2-(Chloromethyl)pyridine hydrochloride
3-(Chloromethyl)pyridine hydrochloride
Benzole acid, 2-hydroxy-, octyl ester
Zinc O,O-dibutyl dithiophosphate
1-Propanol, 2-(dimethylamino)-2-methyl-
p-Chlorophenyl phenyl ether
Acronine
Cyclohexanecarbonitrile, 1 ,3,3-trimethyl-5-oxo-
Nominated

















Yes

























































Yes




















Draft
PCCL3


Yes














Yes

























Yes











Yes









Yes














Yes















Final
PCCL3


Yes














Yes

























Yes











Yes









Yes














Yes















Draft
CCL 3
































































































Public
Comment





Yes
































































Yes




Yes




















Final
CCL 3
































































































CCL 2
































































































CCL1
































































































        A5-42

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
7057923
7078980
7085190
7085850
7128645
7166190
7173515
7177482
7212444
7220793
7235407
7287196
7320345
7320378
7327608
7328178
7336201
7345699
7365459
7379273
7398698
7400080
7414837
7425141
7429905
7439896
7439932
7439954
7439965
7439987
7440020
7440031
7440097
7440166
7440213
7440224
7440235
7440246
7440291
7440315
7440326
7440337
7440371
7440428
7440451
7440484
7440564
7440622
7440655
7440666
7440677
7440699
7440702
7440746
7442139
7446073
7446095
7446700
7446813
7447407
7447418
7473985
7481892
7486386
7488564
7488702
7492300
7492446
7492559
7493574
7493745
7534943
7550450
7553562
7558636
7558794
7558807
7560830
7581977
7585208
7585399
7585413
7601549
7631869
7631905
7631950
7632044
7632055
7632500
7637072
7646788
7646799
7646857
7646937
7647010
7647101
Common Name
Phosphoric acid, didodecyl ester
2,5-Cyclohexadien-1-one, 2,6-bis(1,1-dimethylethyl)-4-
MECOPROP
2-Propenoic acid, 2-cyano-, ethyl ester
2,5-Bis(5-tert-butylbenzoxazol-2-yl)thiophene
.beta.-Bromo-.beta.-nitrostyrene
Didecyl dimethyl ammonium chloride
Ampicillin trihydrate
Nerolidol
METHYLENE BLUE TRIHYDRATE
beta carotene
Prometryn
Tetrapotassium pyrophosphate
Oxirane, tetradecyl-
Acetonitrile, 2,2',2"-nitrilotris-
2-Propenoic acid, 2-(2-ethoxyethoxy)ethyl ester
Amsonic acid disodium salt
Sodium tetrathiocarbonate
HEPES
Ethylenediaminetetraacetic acid potassium salt
Diallyldimethylammonium chloride
2-Propenoic acid, 3-(4-hydroxyphenyl)-
Etidronate Disodium
Hexanoic acid, 2-ethyl-, 2-ethylhexyl ester
Aluminum
Iron
Lithium
Magnesium
Manganese
Molybdenum
Nickel
Niobium
Potassium
Rhodium
Silicon
Silver
Sodium
Strontium
Thorium-232
Tin
Titanium
Tungsten
Argon
Boron
Cerium
Cobalt
Germanium
Vanadium
Yttrium
Zinc
Zirconium
Bismuth
Calcium
Indium
Trimethyl Lead
Tellurium oxide
Sulfur dioxide
Aluminum chloride
2-Propenoic acid, sodium salt
Potassium chloride
Lithium chloride
1-Propanone, 2-hydroxy-2-methyl-1-phenyl-
2',3'-DIDEOXYCYTIDINE
Hexanedioic acid, disodium salt
Selenium disulfide
Thyroxine
Potassium ricinoleate
alpha- Butylcinnamaldehyde
2,4-Hexadienoic acid, calcium salt, (2E.4E)-
Benzene, [2-(1-propoxyethoxy)ethyl]-
Acetic acid, phenoxy-, 2-propenyl ester
Isobornyl methacrylate
Titanium tetrachloride
Iodine
L-Glutamic acid, monoammonium salt
Disodium phosphate
Monosodium phosphate
Cyclohexanamine, N-cyclohexyl-N-methyl-
Butane, 2,3-dichloro-
Acetic acid, zirconium salt
.beta.-Cyclodextrin
C.I. Pigment Red 48, barium salt (1:1)
Trisodium phosphate
Silica
Sodium bisulfite
Molybdate (MoO42-), disodium, (T-4)-
Sodium perborate
Sodium phosphate
Ammonium citrate
Boron trifluoride
Stannane, tetrachloro-
Cobalt chloride
Zinc chloride
Potassium bisulfate
Hydrochloric acid
Palladium chloride
Nominated




























Yes







Yes



























































Draft
PCCL3




















Yes








Yes
Yes
Yes
Yes

Yes

Yes
Yes
Yes




Yes

Yes
Yes
Yes












Yes

































Yes

Final
PCCL3




















Yes








Yes
Yes
Yes
Yes

Yes

Yes
Yes
Yes




Yes

Yes
Yes
Yes












Yes

































Yes

Draft
CCL 3





























Yes







Yes







Yes
Yes
Yes
















































Public
Comment





























Yes







Yes







Yes
Yes
Yes

Yes























Yes






















Final
CCL 3





























Yes







Yes







Yes
Yes
Yes
















































CCL 2
























Yes


















Yes



Yes
















































CCL1
























Yes



Yes







Yes






Yes



Yes
















































        AS-43

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
7647145
7647156
7652644
7659861
7664382
7664417
7673098
7681110
7681381
7681494
7681529
7681530
7681574
7681654
7681825
7681938
7691023
7695912
7696120
7699436
7699458
7704349
7705080
7718549
7719097
7719122
7720787
7722647
7722738
7722761
7722841
7722885
7723140
7726956
7727211
7727437
7727540
7733020
7756947
7757815
7757826
7757837
7757871
7757939
7757962
7758012
7758023
7758045
7758056
7758090
7758114
7758169
7758238
7758294
7758874
7758885
7758943
7761888
7772987
7772998
7773037
7773060
7775099
7775146
7775191
7775271
7775419
7775500
7776285
7778189
7778532
7778543
7778703
7778770
7778805
7779273
7779864
7779886
7779900
7782630
7782652
7782878
7782992
7783064
7783188
7783280
7783406
7783666
7783906
7784181
7784283
7785844
7785877
7785888
7786176
7786347
Common Name
Sodium chloride
Sodium bromide
N,N'-Bispropyleneisophthalamide
2-Ethylhexyl thioglycolate
Phosphoric acid
Ammonia
Trichloromelamine
Potassium iodide
Sodium bisulfate
Sodium fluoride
Sodium hypochlorite
Phosphinic acid, sodium salt
Sodium metabisulfite
Cuprous iodide
Sodium iodide
Pimaricin
1,3-Divinyltetramethyldisilazane
Tocopherol acetate
Tetramethrin
Zirconium, dichlorooxo-
Zinc bromide
Sulfur
Ferric chloride
Nickel(ll) chloride
Thionyl chloride
Phosphorus trichloride
Ferrous sulfate
Potassium permanganate
1,3,5-Tris(carbonyl-2-ethyl-1-azidine)benzene
Phosphoric acid, monoammonium salt
Hydrogen peroxide
Tetrasodium pyrophosphate
Phosphorus
Bromine
Potassium persulfate
Barium sulfate
Ammonium peroxydisulfate
Zinc sulfate
Triisobutylene
SODIUM SORBATE
Sodium sulfate
Sodium sulfite
Phosphoric acid, magnesium salt (2:3)
Phosphoric acid, calcium salt (1:1)
1 -OCTENYL SUCCI NIC ANHYDRI DE
Potassium bromate
Potassium bromide
POTASSIUM CYCLAMATE-PROHIBITED
Potassium iodate
Potassium nitrite
Dipotassium phosphate
Diphosphoric acid, disodium salt
Phosphoric acid, calcium salt (2:1)
Sodium tripolyphosphate
Tricalcium phosphate
Cerium fluoride
Ferrous chloride
Silver nitrate
Sodium thiosulfate
Tin chloride
Sulfurous acid, monopotassium salt
Ammonium sulfamate
Sodium chlorate
Sodium hydrosulfite
Sodium metaborate
Sodium persulfate
Silver fluoride
Tristearyl citrate
CALCIUM PHYTATE
Calcium sulfate
Tripotassium phosphate
Calcium hypochlorite
2-Mercaptobenzothiazole potassium salt
Monopotassium phosphate
Potassium sulfate
1 ,3,5-Triethylhexahydro-s-triazine
Zinc hydrosulfite
Zinc nitrate
Phosphoric acid, zinc salt (2:3)
Ferrous sulfate heptahydrate
Germane
Phosphinic acid, potassium salt
Sulfurous acid
Hydrogen sulfide
Ammonium thiosulfate
Phosphoric acid, diammonium salt
Magnesium fluoride
Iodine fluoride
Silver chloride
Aluminum fluoride
ALUMINUM SODIUM SULFATE
Sodium trimetaphosphate
Sulfuric acid, manganese(2+) salt (1:1)
Phosphoric acid, aluminum sodium salt
2,2'-Methylenebis[6-nonyl-p-cresol]
Mevinphos
Nominated
Yes































































































Draft
PCCL3

Yes

Yes

Yes




Yes





















Yes
Yes




























Yes



















Yes
Yes
Yes











Final
PCCL3

Yes

Yes

Yes




Yes





















Yes
Yes




























Yes



















Yes
Yes
Yes











Draft
CCL 3
































































































Public
Comment
Yes































































































Final
CCL 3
































































































CCL 2
































































































CCL1








































Yes























































        AS-44

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
7786676
7786814
7787704
7789415
7789799
7789802
7789993
7790285
7790763
7790923
7790990
7791255
7803512
7803556
7803625
8000417
8000428
8000495
8000928
8001545
8001750
8001885
8002117
8002480
8002651
8003030
8003223
8004873
8004920
8005036
8006540
8006846
8007123
8007189
8007270
8007305
8009038
8013170
8013909
8014139
8015621
8015643
8016237
8016248
8016680
8020835
8021281
8024371
8028420
8028895
8030895
8049476
8052468
8057496
8057623
8061516
8062155
8063523
8065483
9000059
9000117
9000297
9000366
9000402
9000651
9000695
9001734
9002077
9003105
9003207
9003229
9003343
9003398
9003547
9003774
9003876
9004302
9004324
9004346
9004357
9004539
9004540
9004573
9004595
9004620
9004653
9004675
9004700
9004835
9005270
9005327
9005349
9005350
9005361
9005372
9005383
Common Name
Cyclohexanol, 5-methyl-2-(1-methylethenyl)-
Nickel sulfate
Copper bromide
Calcium bromide
Phosphinic acid, calcium salt
Calcium iodate
1-Pentanol, 2-methyl-, acetate
Sodium m-periodate
Calcium pyrophosphate
Hypochlorous acid
Iodine chloride
Sulfuryl chloride
Phosphine
Ammonium vanadate
Silane
Terpineol
Oils, caraway
METHYL OLEATE-PALMITATE MIXTURE
TITANIUM DIOXIDE-CALCIUM SULFATE
Benzalkonium chloride
Ceresin
Oils, birch-tar
POPPY SEED OIL
Malt, ext.
Neem oil
Aspirin mixt. with phenacetin and caffeine
C.I. Solvent Yellow 33
C.I. Basic Violet 1
C.I. Acid Yellow 3
C.I. Acid Black 2
Lanolin
Oils, fennel
Fats, nutmeg butter
C.I. Pigment Yellow 53
Oils, fleabane, Erigeron canadensis
HYDROGEN PEROXIDE SOLUTION
Petrolatum
Sugar, invert
Ion one
Oils, cumin
Oils, ambrette
Oils, angelica
Oils, guaiac wood
HEMPSEEDOIL
Oils, savory, summer
Hydrocarbon oils
Fir oil
Oils, curcuma
RICEBRAN OIL, SULFATED, METHYL ESTERS
Caramel, color
Pyroligneous acids, reaction products with Et ale., distillates
Pancreatin
TALLOW, PROPYLENE GLYCOL ESTER
VALERIAN ROOT, EXTRACT (VALERIANA OFFICINALIS
PASSION FLOWER EXTRACT
Lignosulfonic acid, sodium salt
Lignosulfonic acid
SODIUM OLEYL SULFATE-SODIUM CETYL SULFATE
Demeton
Gum benzoin
Cellulose, carboxymethyl ether
GUAIAC GUM (GUAIACUM SPP.)
Karaya gum
Carob gum
Gum tragacanth
Pectin
Papain
Trypsin
Urea, polymer with formaldehyde and 2-propanone
Acetic acid ethenyl ester, homopolymer
Acetic acid ethenyl ester, polymer with chloroethene
Benzene, 1,4-dinitroso-, homopolymer
Polyvinylpyrrolidone
2-Propenenitrile, polymer with ethenylbenzene
2-Propenoic acid, 2-ethylhexyl ester, homopolymer
EPICHLOROHYDRIN-4,4'-ISOPROPYLIDENE-DI-O-
CARBOXYMETHYL HYDROXYETHYL CELLULOSE
Sodium carboxymethyl cellulose
Cellulose
Cellulose acetate
Dextrin
Dextran
Ethyl cellulose
Edifas A
2-Hydroxyethyl cellulose
Cellulose, 2-hydroxypropyl methyl ether
Cellulose, methyl ether
Nitrocellulose
Poly(oxy-1 ,2-ethanediyl), .alpha.-[2-(tert-dodecylthio)ethyl]-
Starch, 2-hydroxyethyl ether
Alginic acid
Ammonium alginate
Alginic acid, calcium salt
Potassium alginate
Alginic acid, ester with 1,2-propanediol
Alginic acid, sodium salt
Nominated
































































































Draft
PCCL3
































































































Final
PCCL3
































































































Draft
CCL 3
































































































Public
Comment
































































































Final
CCL 3
































































































CCL 2
































































































CCL1
































































































        AS-45

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
9005441
9005598
9005805
9006046
9006239
9006251
9006284
9006422
9008597
9008780
9009545
9010031
9010848
9010939
9010940
9010984
9011067
9011078
9011170
9011807
9016006
9016459
9017372
9019298
9022177
9035909
9036662
9045287
9048468
9050048
9050311
9051494
9052453
9052840
9057027
9078711
10024972
10025679
10025782
10025873
10025919
10026047
10026138
10026241
10028156
10028225
10030736
10031897
10031966
10034852
10034932
10034965
10035048
10039540
10042598
10042849
10043013
10043115
10043353
10045860
10045871
10045893
10058443
10061015
10061026
10094345
10099588
10099715
10101390
10101505
10101970
10102188
10102439
10102440
10117381
10118908
10119536
10124411
10124433
10124568
10143223
10191410
10196040
10213759
10222012
10233133
10258545
10265926
10279637
10294345
10294403
10305790
10318260
10326279
10377669
10380286
Common Name
CHROMIUM CASEINATE
SODIUM PECTINATE
Inulin
Rubber, natural
2-Propenoic acid, methyl ester, polymer with
Formaldehyde, polymer with 1,3,5-triazine
PEG (MW 200-600) ESTERS OF FATTY ACIDS
Metiram
Formaldehyde, polymer with 2-butanone
PEG PPG OCTYLPHENYL ETHER
POLYURETHAN FOAM
SODIUM CAPRYL POLYPHOSPHATE
1 ,3-BUTYLENE GLYCOL-DIGLYCOLIC ACID COPOLYMER
2-Propenoic acid, 2-methyl-, polymer with 1,3-butadiene and
2-Propenoic acid, 2-methyl-, methyl ester, polymer with 1 ,3-
1 ,3-Butadiene, 2-chloro-, homopolymer
Ethene, 1,1-dichloro-, polymer with chloroethene
Acetic acid ethenyl ester, polymer with 2,5-furandione
1-Propene, 1,1,2,3,3,3-hexafluoro-, polymer with 1,1-
Hexanedioic acid, polymer with 1 ,3-isobenzofurandione and
Poly[oxy(dimethylsilylene)]
Polyethylene glycol nonylphenyl ether
2-Propenoic acid, 2-methyl-, methyl ester, polymer with
Butene, polymer with ethene
2-Propen-1-aminium, N,N-diethyl-N-2-propenyl-, chloride,
2-Propenoic acid, 2-methyl-, methyl ester, polymer with 1 ,3-
D-Galacto-L-arabinan
Starch, acetate
Albumins, blood serum
Carboxymethylcellulose calcium
Hydroxypropylmethylcellulose phthalate
Poly[oxy(methyl-1 ,2-ethanediyl)], .alpha.-hydro-.omega.-
2-Propenoic acid, polymer with diethenylbenzene
Benzene, diethenyl-, polymer with 1,3-butadiene and
Pullulan
1 ,4-Benzenedicarboxylic acid, dimethyl ester, polymer with
Nitrous oxide
Sulfur monochloride
Trichlorosilane
Phosphorus oxychloride
Antimony trichloride
Silane, tetrachloro-
Phosphorus pentachloride
Sulfuric acid, cobalt(2+) salt (1:1), heptahydrate
Ozone
Ferric sulfate
9-Hexadecenoic acid, (9E)-
ETHYLENE GLYCOL MONOETHYL ETHER RICINOLEATE
EUGENYL FORMATE
Hydriodic acid
Hydrazine, sulfate (1:1)
Manganous sulfate monohydrate
CALCIUM CHLORIDE
Hydroxylamine, sulfate (2:1) (salt)
1-Heptanol, 2-propyl-
Nitrilotriacetic acid sodium salt
Aluminum sulfate
Boron nitride
Orthoboric acid
Ferric phosphate
FERRIC SODIUM PYROPHOSPHATE
Ferrous ammonium sulfate
Ferric pyrophosphate
1-Propene, 1,3-dichloro-, (Z)-
trans-1,3-Dichloropropene
Butanoic acid, 1,1-dimethyl-2-phenylethyl ester
Lanthanum chloride
2-Butenedioic acid (2Z)-, dipentyl ester
Calcium metasilicate
Sodium permanganate
Nickel(ll) sulfate hexahydrate
Disodium selenite
Nitric oxide
Nitrogen dioxide
Sulfurous acid, dipotassium salt
MINOCYCLINE
Octadecanoic acid, cerium salt
Calcium thiosulfate
Cobalt(l I) sulfate
Sodium hexametaphosphate
2-Methoxyethyl dimethylolcarbamate
dl-alpha-Tocopherol
Ammonium sulfite
Propanenitrile, 3-[(2-ethylhexyl)oxy]-
2,2-Dibromo-3-nitrilopropionamide
Isopropyl laurate
Acetic acid, cyano-, 2-methoxyethyl ester
Methamidophos
Potassium chromium sulfate
Boron trichloride
Chromic acid (H2CrO4), barium salt (1:1)
Diphosphoric acid, aluminum sodium salt
Galactitol, 1 ,6-dibromo-1 ,6-dideoxy-
Barium chloride (BaCI2), dihydrate
Manganese nitrate
Copper 8-quinolinolate
Nominated





















Yes










































































Draft
PCCL3







Yes




































Yes










































Yes








Final
PCCL3







Yes




































Yes










































Yes








Draft
CCL 3























































































Yes








Public
Comment





















Yes





















































Yes




















Final
CCL 3























































































Yes








CCL 2
































































































CCL1
































































































        AS-46

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
10416598
10419973
10436392
10453868
10476956
10482561
10486198
10491313
10508095
10519116
10543574
10545990
10563265
10563298
10584982
10595956
10605217
11070443
11084858
11096825
11099039
11103869
11104282
11130293
11138662
11141165
11141176
12001262
12001284
12001331
12001795
12001853
12002436
12007588
12024214
12030976
12035722
12057748
12060581
12064629
12068030
12069328
12069691
12070121
12075682
12108133
12111249
12122677
12124979
12125029
12135761
12168853
12172735
12174117
12224021
12225182
12235211
12236623
12407862
12427382
12510428
12602232
12607704
12624350
12645497
12645500
12645533
12656858
12672296
12738646
12768784
13010474
13023002
13029088
13047137
13048334
13071799
13080869
13106768
13108526
13116535
13121705
13150000
13167367
13171216
13183794
13194484
13244332
13244354
13254347
13256116
13290965
13292870
13323621
13356086
13360639
Common Name
N,O-Bis(trimethylsilyl)acetamide
2,3,5,6-TETRACHLORO-4-(METHYLSULFINYL)PYRIDINE
1-Propene, 1,1,2,3-tetrachloro-
Resmethrin
Methacrolein diacetate
(L)-alpha-Terpineol
Tridecanal
Sodium bis(p-tert-butylphenyl) phosphate
Peroxide, bis(1,1-dimethylpropyl)
2-Naphthalenol, decahydro-, acetate
Tetraacetylethylenediamine
Sulfur chloride
1 ,3-Propanediamine, N,N"-1 ,2-ethanediylbis-
Dimethyldipropylenetriamine
Di-n-butyltin di-2-ethylhexylthioglycolate
N-Nitrosomethylethylamine
Carbendazim
1 ,3-lsobenzofurandione, tetrahydromethyl-
Sodium hypochlorite phosphate
Aroclor1260
C.I. Solvent Black 5
Potassium zinc chromate hydroxide
Aroclor1221
Yttrium oxide
Xanthan gum
Aroclor1232
Azadirachtin A
Mica-group minerals
Crocidolite asbestos
ASPHALT, NAPHTHENIC
Vitamin K
Zinc naphthenate
Gilsonite
Ammonium boron oxide
Gallium oxide
Potassium titanium oxide
Nickel subsulfide
Magnesium phosphide
Samarium oxide
Gadolinium oxide
Sodium toluenesulfonate
Boron carbide
Copper carbonate, basic
Tungsten carbide
Aluminum, di-.mu.-chlorochlorotriethyldi-
Methylcyclopentadienyl manganese tricarbonyl
Pentetate Calcium Trisodium
Zineb
Ammonium bromide
Ammonium chloride
Ammonium sulfide
Tricalcium silicate
Amosite asbestos
Attapulgite
C.I. Fluorescent Brightener24
C.I. Pigment Yellow 97
C.I. Acid Yellow 135
C.I. Pigment Orange 36
Trimethacarb
Maneb
Erionite
Cobalt carbonate hydroxide
Nickel carbonate hydroxide
9,12-Octadecadienoic acid (9Z,12Z)-, dimer, polymer with 1,2
Iron manganese zinc oxide
Iron nickel zinc oxide
Phosphoric acid, isooctyl ester
C.I. Pigment Red 104
Aroclor1248
Sucrose benzoate
C.I. Acid Green 16
Urea, N-(2-chloroethyl)-N'-cyclohexyl-N-nitroso-
2,2-Dichlorobutanoic acid
2,2'-Dichlorobiphenyl
Dimezone S
2-Propenoic acid, 1,6-hexanediyl ester
Terbufos
2,2'-Bis(4-aminophenoxyphenyl)propane
Molybdate (MoO42-), diammonium, (T-4)-
2,3,5,6-Tetrachloro-4-(methylsulfonyl)pyridine
Propane, 1,2,2,3-tetrachloro-
Cyhexatin
Dodecyltriethoxy sulfate
3,3-Dichloropropenoic acid
Phosphamidon
5H-Tetrazole-5-thione, 1 ,2-dihydro-1-methyl-
Ethoprop
Benzenesulfonic acid, 2-amino-5-methoxy-
Benzenamine, 2-chloro-4-(methylsulfonyl)-
2-Heptanol, 2,6-dimethyl-
Nitroso-N-methyl-N-(2-phenyl)ethylamine
Dimethyl 5-nitroisophthalate
Boron, trihydro[thiobis[methane]]-, (T-4)-
Dibutyltin dioleate
Fenbutatin oxide
1-Butanamine, N-ethyl-
Nominated
































































































Draft
PCCL3















Yes
Yes




























Yes













Yes
















Yes









Yes







Yes

Final
PCCL3















Yes
Yes




























Yes













Yes
















Yes









Yes







Yes

Draft
CCL 3












































































Yes









Yes









Public
Comment



















































































Yes












Final
CCL 3












































































Yes









Yes









CCL 2












































































Yes



















CCL1












































































Yes



















        A5-47

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
13366739
13403015
13410010
13426910
13463393
13463406
13463417
13463677
13464807
13466789
13472087
13494809
13530659
13547701
13548384
13552448
13560899
13590971
13593038
13598362
13598373
13601199
13674845
13674878
13676545
13684565
13684634
13718268
13746662
13752517
13770962
13822565
13826352
13845368
13863315
13863417
13878541
13889924
13909096
13927770
13939258
13952846
13963570
13983170
13988266
14020521
14024181
14025151
14038438
14047097
14075537
14150711
14205391
14221477
14239680
14265442
14295433
14302137
14307336
14324551
14351407
14371109
14380622
14433762
14481266
14481299
14484641
14492683
14567738
14765301
14797730
14807966
14808607
14808798
14814096
14857342
14860538
14866683
14901076
15086949
15096523
15214898
15242963
15275077
15299997
15336820
15337607
15356704
15481706
15521650
15546119
15546120
15546164
15547178
15569854
15570102
Common Name
Photodieldrin
2-(2,4-Di-tert-pentylphenoxy)butyric acid
Sodium selenate
Copper(2+), bis(ethylenediamine)-, ion
Nickel carbonyl
Iron pentacarbonyl
Zinc pyrithione
Titanium dioxide
Hydrazine, sulfate (2:1)
Bicyclo[4.1.0]hept-3-ene,3,7,7-trimethyl-
Butanenitrile, 2,2'-azobis[2-methyl-
Tellurium
Zinc chromate
2-Butanone, 1-chloro-3,3-dimethyl-
Nitric acid, chromium(3+) salt
Benzenamine, 4,4'-methylenebis-, dihydrochloride
Dechlorane plus
Dodecylguanidine hydrochloride
Quinalphos
Phosphonic acid
Phosphoric acid, zinc salt (2:1)
Sodium ferrocyanide
2-Propanol, 1-chloro-, phosphate (3:1)
2-Propanol, 1,3-dichloro-, phosphate (3:1)
Bis(4-maleimidophenyl)methane
Desmedipham
Phenmedipham
Sodium vanadate
Potassium ferricyanide
Cure-Rite 18
Sodium aluminum hydride
1-Propanamine, 3-(trimethoxysilyl)-
3-Phenoxybenzenemethanol
Potassium tripolyphosphate
Tinopal 5bm
Bromine chloride
Zinc pentamethylenedithiocarbamate
Carbonochloridothioic acid, S-propyl ester
Semustine
Nickel dibutyldithiocarbamate
Aluminium dihydrogen triphosphate
sec-Butylamine
Aluminum(lll) acetylacetonate
Wollastonite
Diethylene glycol bisphthalate
2,2'-METHYLENEBIS(4-METHYL-6-TERT-OCTYLPHENOL)
Ferric tris(acetoacetonate)
Copper versenate
Ferric ferrocyanide
Diazene, bis(3,4-dichlorophenyl)-
Potassium tetrafluoroborate
Thiocyanic acid, 1 ,2-ethenediyl ester
2-Butenoic acid, 3-amino-, methyl ester
Triammonium trioxalatoferrate(S-)
Cadmium diethyldithiocarbamate
Phosphate
C.I. Pigment Red 88
C.I. Pigment Green 36
Calcium dichromate(VI)
Ethyl ziram
STEAROYL MONOETHANOLAMIDE STEARATE
trans-Cinnamaldehyde
Hypobromite
Decanamide, N,N-dimethyl-
Titanium potassium oxalate
Ammonium ferrocyanide
Ferbam
Steapyrium chloride
Tremolite
Cyclohexanone, 2-(1-methylpropyl)-
Perchlorate
Talc
Quartz
Sulfate
1-Propanethiol, S-(triethoxysilyl)-
Silane, ethoxydimethyl-
Tetrapotassium etidronate
Chlorate
beta-Cyclocitrylideneacetone
D&CRedno. 21
Cryolite
2-Acrylamido-2-methylpropanesulfonate
Stearatochromic chloride
EDTA, IRON (III)
Napropamide
5-Ethyl-1,3-diglycidyl-5-methylhydantoin
Barium cadmium laurate
dl-Menthol
1 ,3-Benzenediamine, 2-methyl-, dihydrochloride
Nickel dimethyldithiocarbamate
Dibutyltin bis(monomethyl maleate)
Dibutyltin bis(2-ethylhexyl maleate)
Dibutyltin bis(monobutyl maleate)
9,10-Anthracenedione, 6-ethyl-1,2,3,4-tetrahydro-
2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-
4-TERT-BUTYL-O-THIOCRESOL
Nominated






































































Yes























Yes

Draft
PCCL3





Yes





Yes















Yes

Yes




































Yes



Yes

Yes







Yes















Final
PCCL3





Yes





Yes















Yes

Yes




































Yes



Yes

Yes




Yes


Yes















Draft
CCL 3











Yes


























































Yes

























Public
Comment







Yes














Yes
Yes














































Yes






Yes


















Final
CCL 3











Yes


























































Yes






Yes


















CCL 2






































































Yes

























CCL1






































































Yes


Yes






















        AS-48

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
15572562
15625895
15647082
15687271
15708415
15748739
15791783
15805739
15875135
15905325
15922788
16008314
16008325
16045924
16066389
16068374
16071866
16079882
16090021
16091182
16110091
16111276
16111629
16219753
16227104
16301261
16368971
16409431
16423680
16470249
16485102
16521383
16529569
16532799
16561298
16587716
16588673
16655826
16669593
16672870
16691433
16709301
16712644
16714684
16715836
16721805
16731558
16752775
16813368
16867042
16887006
16889104
16893859
16919190
16940662
16961834
16995350
17026812
17095248
17140602
17157481
17201159
17261288
17265144
17268472
17292625
17321470
17348593
17351756
17356422
17372871
17418585
17420303
17421793
17462587
17465860
17511603
17557232
17557674
17598651
17639939
17655640
17688685
17697539
17697551
17741627
17754904
17766266
17796826
17804352
17804498
17831719
17924924
18039424
18069175
18127010
Common Name
2-Propanamine, hydrochloride
Trimethylolpropane triacrylate
Phosphorous acid, 2-ethylhexyl diphenyl ester
Ibuprofen
Sodium feredetate
Lead disalicylate
C.I. Disperse Blue 27
Vinyl carbamate
R 1 41 (catalyst)
2',4',5',7'-Tetraiodofluorescein
2(1H)-Pyridinethione, 1-hydroxy-, sodium salt
1-Butanesulfonothioic acid, S-(chloromethyl) ester
1-Butanesulfonic acid, thio-, S,S'-methylene ester
Chlorobutanedioic acid
Peroxydicarbonic acid, dipropyl ester
3,8-Dioxa-4,7-disiladecane, 4,4,7,7-tetraethoxy-
C.l. Direct Brown 95
1-Bromo-3-chloro-5,5-dimethylhydantoin
Tinopal DMS
1 ,3,2-Dioxastannepin-4,7-dione, 2,2-dioctyl-
2,5-DICHLOROPYRIDINE
Nordimaprit
Peroxydicarbonic acid, bis(2-ethylhexyl) ester
5-Ethylidene-2-norbornene
Triazbutil
Z-Ethyl-O,N,N-azoxyethane
Phosphoric acid, bis(2-ethylhexyl) phenyl ester
Rosenoxide
2',4',5',7'-Tetraiodofluorescein, disodium salt
C.I. Fluorescent Brightener 220
Panthenol
C.I. Pigment Blue 63
3-Butenenitrile, 2-methyl-
Benzeneacetonitrile, 4-bromo-
Tetradecanoylphorbol acetate
Cyclohexanone, 4-(1,1-dimethylpropyl)-
Propanenitrile, 3-[ethyl[3-methyl-4-[[6-(methylsulfonyl)-2-
3-Hydroxycarbofuran
2-Propenamide, N-[(2-methylpropoxy)methyl]-
Ethephon
3H-1 ,2,4-Triazole-3-thione, 5-amino-1 ,2-dihydro-
3-Ketocarbofuran
2-Naphthalenecarboxylic acid, 6-hydroxy-
Propane, 1,1,2,2,3-pentachloro-
Diisopropylaminoethyl methacrylate
Sodium hydrosulfide
Disulfurous acid, dipotassium salt
Methomyl
1 -Nitroso-5,6-dihydrouracil
2,3-Dihydroxypyridine
Chloride
Fantagen-rubine
Sodium fluosilicate
Ammonium silicofluoride
Borate(l-), tetrahydro-, sodium
Fluosilicic acid
1,1,1,3-Tetrachloropropanone
Acetamide, N-(3-amino-4-ethoxyphenyl)-
C.l. Reactive Blacks
Calcium glucoheptanoate
Bromoacetaldehyde
2,6-BIS((2-HYDROXY-5-METHYL-3-
Benzoic acid, 2-(diphenylphosphino)-
Disodium sebacate
Propanamide, 3-(dimethylamino)-N,N-dimethyl-
Cyanamide, monosodium salt
Phosphoramidothioic acid, O,O-dimethyl ester
tert-Butyl isopropyl ether
Cyclohexane, 1 ,4-bis[(ethenyloxy)methyl]-
Ethion monooxon
Eosine Yellowish-(YS)
C.I. Disperse Red 60
Benzonitrile, 2-amino-5-nitro-
Ethylenediaminetetraacetic acid sodium salt
Carbonochloridic acid, 1-methylpropyl ester
.gamma.-Cyclodextrin
Tricyclodecenyl propionate
Neopentyl glycol diglycidyl ether
2-Benzothiazolamine, 6-(methylsulfonyl)-
Deslanoside
Methyl 2-chloropropionate
1 ,1,5,5-Tetrachloropentane
Thiomorpholine, 4-phenyl-, 1,1-dioxide
2-Azoxypropane
1-Azoxypropane
Thiomorpholine, 4-[4-[(2,6-dichloro-4-nitrophenyl)azo]phenyl]-
Benzaldehyde, 4-(diethylamino)-2-hydroxy-
1 ,3, 5- Triazin e-2,4,6(1 H,3H,5H)-trithione, trisodium salt
1 H-lsoindole-1 ,3(2H)-dione, 2-(cyclohexylthio)-
Benomyl
C.I. Reactive Red 2
Tetraethylene glycol diacrylate
Zearalenone
1 H-Tetrazole, 5-phenyl-
2-Methylpentanedioic acid
Benzenepropanal, 4-(1,1-dimethylethyl)-
Nominated


















































Yes









Yes



































Draft
PCCL3























Yes













Yes

Yes







Yes
















































Final
PCCL3























Yes













Yes

Yes







Yes
















































Draft
CCL 3





































Yes


























































Public
Comment



Yes











































Yes








Yes



Yes



































Final
CCL 3





































Yes


























































CCL 2
































































































CCL1
































































































        AS-49

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
18162486
18268707
18328900
18472872
18559949
18662538
18760446
18869733
18871142
18883664
18908162
18996355
19009564
19010663
19044883
19219999
19351189
19355692
19356173
19430934
19466478
19473495
19485031
19526819
19666309
19721223
19889373
19900653
19910657
20018091
20068024
20120336
20139553
20150349
20190005
20232240
20265967
20265978
20324338
20325400
20336963
20354261
20427592
20587615
20679587
20816120
20830755
20830813
20859738
20917491
20941655
21087649
21145777
21232473
21260468
21302090
21351393
21416875
21436964
21564170
21645512
21679312
21722838
21725462
21739913
21829254
22031330
22042962
22204531
22205307
22208259
22224926
22248799
22326314
22398807
22457234
22499123
22578865
22591215
22781233
22839470
22966796
23010040
23103982
23128747
23184669
23246960
23383111
23386529
23422539
23436193
23564058
23564069
23726912
23850944
23950585
Common Name
Silane, chloro(1,1-dimethylethyl)dimethyl-
Tetraethylene glycol di(2-ethylhexoate)
2-Propen-1-amine, N-ethyl-2-methyl-
Phloxine B
Salbutamol
NTA trisodium salt dihydrate
Thiophene, 3-(decyloxy)tetrahydro-, 1,1-dioxide
Triacetyldiphenolisatin
2H-Pyran-4-ol, tetrahydro-3-pentyl-, acetate
Streptozotocin
1,2-DIMETHYL-4-(1-METHYLETHENYL)BENZENE
Sodium citrate
Decanal, 2-methyl-
Lead dimethyldithiocarbamate
Oryzalin
Benzoxazole, 5-chloro-2-methyl-
Thiazolidine, 2,2-dimethyl-
Propanenitrile, 2-amino-2-methyl-
Calcifediol
1-Hexene, 3,3,4,4,5,5,6,6,6-nonafluoro-
beta-stigmastanol
L-Glutamic acid, monopotassium salt
2-Propenoic acid, 1-methyl-1 ,3-propanediyl ester
Remazol Red B
Oxadiazon
1-Propanol, 3-mercapto-
Butanoic acid, 2-ethyl-2-methyl-
Benzenamine, 4,4'-methylenebis[2-ethyl-
Peroxydicarbonic acid, bis(l-methylpropyl) ester
Diiodomethyl p-tolyl sulfone
2-Butenenitrile, 2-methyl-, (2Z)-
N-Methylol dimethylphosphonopropionamide
Butanamide, N-(4-chloro-2-methylphenyl)-3-oxo-
Ferrous bisglycinate ch elate
Dipentaerythritol pentastearate
4,4'-ISOPROPYLIDENEDIPHENOL- EPICHLOROHYDRIN
Benzenamine, 4-chloro-, hydrochloride
Benzenamine, 4-methoxy-, hydrochloride
Tripropyleneglycol monomethyl ether
o-Dianisidine dihydrochloride
Lithium myristate
Methazole
Cupric hydroxide
Ethanol, 2-[2-(benzoyloxy)ethoxy]-
1 ,4-Bis(bromoacetoxy)-2-butene
Osmium tetroxide
Digoxin
Daunomycin
Aluminum phosphide
Nitrosoheptamethyleneimine
Ethyl tellurac
Metribuzin
Tonalid
Diazene, bis(3,4-dichlorophenyl)-, 1 -oxide
Bismuth dimethyldithiocarbamate
Dilauryl phosphite
Urea sulfate
ICRF-159
2,4-Xylidine.HCI
2-(Benzothiazolylthio)methyl thiocyanate
Aluminum hydroxide
Chromium(lll) acetylacetonate
Cyclohexaneethanol, acetate
Cyanazine
Cytembena
Nifedipine-dehydro
Propanenitrile, 3-[[2-(acetyloxy)ethyl]phenylamino]-
Wayplex 55S
Naproxen
Stannane, bis(dodecylthio)dioctyl-
Trimethylolpropanetriacetoacetate
Fenamiphos
Tetrachlorvinphos
1 ,3-Benzenedicarboxylic acid, 5-sulfo-
Indium phosphide
3-Heptanone, 5-methyl-, oxime
Ethanone, 2-(2-methylpropoxy)-1 ,2-diphenyl-
Acetamide, N-[2-[(2-bromo-4,6-dinitrophenyl)azo]-5-[(2-
2-Butanone, 1 ,1-dichloro-3,3-dimethyl-
Bendiocarb
Aspartame
Estradiol mustard
1 ,2-Dichloro-2-methyl butane
Pirimicarb
Benzenepropanamide, N,N'-1,6-hexanediylbis[3,5-bis(1,1-
Butachlor
Riddelline
FERROUS CITRATE
Dicyclohexyl sodium sulfosuccinate
Formetanate hydrochloride
Propylene glycol monoisobutyl ether
Thiophanate-methyl
Thiophanate ethyl
(E)-beta-Damascone
Stannane, butyltris[(2-ethyl-1-oxohexyl)oxy]-
Pronamide
Nominated




Yes









































Yes

















































Draft
PCCL3
























Yes














Yes











Yes











Yes







Yes

















Yes

Yes




Final
PCCL3
























Yes














Yes











Yes











Yes







Yes

















Yes

Yes




Draft
CCL 3







































































Yes



















Yes




Public
Comment




Yes















Yes

























Yes


















Yes


Yes


Yes
























Final
CCL 3







































































Yes



















Yes




CCL 2
































































































CCL1



















































Yes












































        AS-50

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
24072751
24237001
24245270
24305279
24307264
24308847
24382045
24424995
24468131
24473061
24544045
24549062
24565137
24579735
24623776
24634615
24650428
24689892
24748230
24800440
24801885
24851987
24937799
24938123
24938190
24938678
24981144
25013154
25013165
25014419
25034586
25035750
25035896
25035909
25035976
25038373
25053570
25057890
25067054
25067349
25068262
25085465
25085829
25086151
25086480
25101455
25103097
25103122
25103520
25103542
25103586
25119624
25133986
25134081
25134218
25152845
25154523
25155231
25155253
25155297
25155300
25167673
25167800
25168052
25168245
25190878
25190890
25212060
25212742
25213267
25214486
25248424
25249165
25249609
25264931
25265194
25265718
25265774
25266573
25311711
25321099
25321146
25321226
25322207
25323244
25323584
25327893
25329355
25339097
25339177
25340174
25340185
25359915
25360105
25376458
25377724
Common Name
2-Benzothiazolamine, 5,6-dichloro-
2H-Pyran, 6-butyl-3,6-dihydro-2,4-dimethyl-
Diphenylguanidine hydrochloride
Protirelin
Mepiquat chloride
Zinc bis(benzenesulphinate)
Propanedial, ion(1-), sodium
Dicarbonic acid, bis(1,1-dimethylethyl) ester
Carbonochloridic acid, 2-ethylhexyl ester
2-Butanone, 1-(4-chlorophenoxy)-3,3-dimethyl-
Benzenamine, 2,6-bis(1-methylethyl)-
Benzenamine, 2-ethyl-6-methyl-
C.l. Fluorescent Brightener 208
Propamocarb
Aluminum hydroxide oxide
2,4-Hexadienoic acid potassium salt, (E,E)-
Ethanone, 2,2-dimethoxy-1 ,2-diphenyl-
Chloroethylene bisthiocyanate
1 ,2,4,5,7,8-Hexoxonane, 3,6,9-triethyl-3,6,9-trimethyl-
Propanol, [(1-methyl-1 ,2-ethanediyl)bis(oxy)]bis-
Silane, triethoxy(S-isocyanatopropyl)-
Methyl (2-pentyl-3-oxocyclopentyl)acetate
Ethene, 1,1-difluoro-, homopolymer
2-Butenedioic acid (2E)-, polymer with 1,3-butadiene and
POLY(ACRYLAMIDE-CO-ETHYLACRYLATE-CO-
POLY(2,6-DIMETHYL-1 ,4-PHENYLENE OXIDE)
Ethene, fluoro-, homopolymer
Vinyltoluene
Butylated hydroxyanisole
2-Propenenitrile, homopolymer
2-Propenamide, N,N'-methylenebis-, polymer with 2-
2-Propenoic acid, ethyl ester, polymer with ethenylbenzene
2-Propenoic acid, 2-methyl-, polymer with butyl 2-
2-Butenedioic acid (2Z)-, dibutyl ester, polymer with ethenyl
2-Propenoic acid, ethyl ester, polymer with chloroethene
1 ,4-Hexadiene, polymer with ethene and 1-propene
5-lsobenzofurancarboxylic acid, 1 ,3-dihydro-1 ,3-dioxo-,
Bentazon
Polyglycidyl methacrylate
Ethenol, polymer with ethene
1-Pentene, 4-methyl-, homopolymer
Acetic acid ethenyl ester, polymer with chloroethene and
Acetic acid ethenyl ester, polymer with chloroethene and 2,5-
2-Propenoic acid, 2-methyl-, polymer with methyl 2-methyl-2-
Acetic acid ethenyl ester, polymer with chloroethene and
Ethene, chlorotrifluoro-, polymer with ethene
Isooctyl thioglycolate
Phosphorous acid, triisooctyl ester
Isooctanoic acid
Zinc isodecyl phosphorodithioate
tert-Dodecanethiol
2-Propen-1-ol, polymer with ethenylbenzene
2-Propenoic acid, 2-methyl-, polymer with 2-ethylhexyl 2-
Benzoyl chloride, dichloro-
Methyl nadic anhydride
2,4-Decadienal, (2E,4E)-
Nonylphenol
Phenol, dimethyl-, phosphate (3:1)
Bis(tert-butyldioxyisopropyl)benzene
Urea, bis(hydroxymethyl)-
Sodium dodecylbenzenesulfonate
Butene
Chlorophenol
Chlorotoluene
Dibutyltin diisooctylthioglycolate
Bicyclo[2.2.1]hepta-2,5-diene, polymer with ethene, 1,4-
1-Propene, 1,1,2,3,3,3-hexafluoro-, polymer with 1,1-
Hexanedioic acid, polymer with 1 ,6-hexanediol
POLY(1 ,4-PHENYLENE SULFIDE)
STYRENE-VINYLIDENE CHLORIDE COPOLYMER
POLY(METHYL METHACRYLATE-CO-VINYL ALCOHOL)
POLY(OXYCARBONYLPENTAM ETHYL EN E)
POLY(2-HYDROXYETHYL METHACRYLATE)
Butanedioic acid, methylene-, polymer with 1,1-
Hexene
2-Propenoic acid, polymer with 1 ,3-butadiene and 2-
Dipropylene glycol
Texan ol
POLY(1-HEXENE-CO-MALEIC AN HYDRIDE)
Isofenphos
Benzene, bis(l-methylethyl)-
Dinitrotoluene
Dichlorobenzene
Tetrachloroethane
HEXANETRIOL
Oxetane, 3,3-bis(chloromethyl)-, homopolymer
Tetrabromobisphenol A bis(allyl ether)
1 ,3-Cyclopentadiene, 1 , 2,3,4, 5-pentachloro-
Octadecanoic acid, isohexadecyl ester
Isodecanol
Diethylbenzene
Benzene, triethyl-
FORMALDEHYDE, POLYMER WITH 1- NAPHTHYLENOL
tert-Nonanethiol
Toluenediamine
Pentene
Nominated





































Yes


















Yes







































Draft
PCCL3




Yes






















Yes
Yes








Yes






















Yes

Yes













Yes
Yes



Yes








Yes





Final
PCCL3




Yes






















Yes
Yes








Yes






















Yes

Yes













Yes
Yes



Yes








Yes





Draft
CCL 3




























Yes



































































Public
Comment




























Yes



























Yes







































Final
CCL 3




























Yes



































































CCL 2
































































































CCL1
































































































        A5-51

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
25377735
25377837
25378227
25395317
25417203
25448253
25485885
25496724
25497307
25498060
25498491
25511711
25550145
25551137
25564221
25584832
25586430
25609896
25610848
25619094
25640782
25646713
25685294
25702801
25718701
25721760
25747744
25747755
25750065
25750827
25750849
25805178
25812300
25822519
25834804
25843452
25852704
25869005
25895447
25895470
25899507
25954136
25956176
25973551
26002802
26007432
26062793
26062942
26099092
26115708
26124254
26125519
26140603
26172554
26175702
26225796
26248248
26248420
26249207
26264062
26266580
26266682
26266773
26299605
26322145
26337235
26337359
26338669
26375235
26377297
26399360
26401865
26401978
26444495
26446355
26447143
26471625
26472004
26538443
26544230
26544387
26568809
26587280
26589264
26590205
26602040
26602095
26628228
26636011
26636328
26636328
26638197
26644462
26651967
26659030
26713144
Common Name
2,5-Furandione, 3-(dodecenyl)dihydro-
Octene
Dodecene
1,2,3-Propanetriol, diacetate
Dibutylnaphthalenesulfonic acid sodium salt
Triisodecyl phosphate
Benzoic acid, 2-hydroxy-, cyclohexyl ester
Glyceryl monooleate
DIBROMOTETRAFLUOROETHANE
Cyclohexane, ethenyl-, homopolymer
Tripropylene glycol methyl ether
POLY(PROPYLENE-CO- VI NYLIDENE CHLORIDE)
Benzene, ethylmethyl-
Benzene, trimethyl-
2-Cyclopenten-1-one, 2-pentyl-
2-Propenoic acid, monoester with 1 ,2-propanediol
Chloronaphthalene
2-Butenoic acid, polymer with ethenyl acetate
Aziridine, polymer with (chloromethyl)oxirane
Formaldehyde, polymer with 2-propanone
1,1'-Biphenyl, (1-methylethyl)-
Kodak CD-3
2-Propenoic acid, 2-methyl-, ethyl ester, polymer with methyl
2-Propenoic acid, polymer with chloroethene
Hexanedioic acid, polymer with 1 ,3-benzenedimethanamine
2-Propenoic acid, 2-methyl-, 1,2-ethanediyl ester,
2-Propenenitrile, polymer with (l-methylethenyl)benzene
2-Propenoic acid, 2-methyl-, methyl ester, polymer with (1-
2-Propenoic acid, 2-methyl-, methyl ester, polymer with
2-Propenoic acid, polymer with ethene, sodium salt
2-Propenoic acid, butyl ester, polymer with ethene
Oxazole, 2-ethyl-4,5-dihydro-, homopolymer
Gemfibrozil
POLY(VINYL ALCOHOL-CO-VINYL CHLORIDE)
Benzenamine, 2,4-bis[(4-aminophenyl)methyl]-
Diazene, dimethyl-, 1-oxide
Butyltin tris(isooctylmercaptoacetate)
Ammonium iron (III) hexacyanoferrate
POLY(I-HEXENE-CO-PROPYLENE)
1-Butene, polymer with ethene and 1-propene
2-Pentenenitrile, (2Z)-
Fosamine-ammonium
C.I. Food Red 17
2-(2H-Benzotriazol-2-yl)-4,6-ditertpentylphenol
Phenothrin
Bicyclo[2.2.1]hept-2-ene, polymer with ethene
Poly(dimethyl diallyl ammonium chloride)
1 ,4-Benzenedicarboxylic acid, polymer with 1 ,4-butanediol
2-Butenedioic acid (2Z)-, homopolymer
1 ,3,5-Triazine-2,4,6(1 H,3H,5H)-trione, 1 ,3,5-tris[3-
POLY(VINYL ACETATE-CO-VINYL PROPIONATE- CO-
2-Propenoic acid, polymer with ethene and 1-propene
Terphenyl
5-Chloro- 2-methyl- 4-isothiazolin-3-one
1 ,3,5-TRIS(3,5-DI-TERT-BUTYL-4-
Ethofumesate
Sodium tridecylbenzenesulfonate
Tridecanol
Butane, epoxy-
Calcium dodecylbenzenesulfonate
Sorbitan, tri-(9Z)-9-octadecenoate
2-Ethylhexenal
Dihydroabietyl alcohol
POLY(ACRYLIC ACID-CO-VINYL ALCOHOL)
Peroxydicarbonic acid, dihexadecyl ester
2-Propenenitrile, polymer with 1,3-butadiene and
Acetic acid ethenyl ester, polymer with carbon monoxide and
POLY(ACRYLAMIDE-CO-N-METHYLOACRYLAMIDE)
Hexanedioic acid, polymer with 1 ,4-butanediol and 1,1'-
Sodium dimethyl dithiophosphate
Profluralin
Monooctyltin tris(isooctylthioglycollate)
Dioctyltin-S,S'-bis(isooctylmercaptoacetate)
Phosphoric acid, methylphenyl diphenyl ester
1,2,3-Propanetriol, monoacetate
Cresyl glycidyl ether
Toluene diisocyanate
Methylcyclopentadiene dimer
Zeranol
Phosphorous acid, isodecyl diphenyl ester
2,5-Furandione, dihydro-S-(tetrapropenyl)-
2-Propenoic acid, polymer with 1 ,3-butadiene,
POLY(ETHYLENE-CO-I-OCTENE-CO-PROPYLENE)
2-Propenoic acid, 2-methyl-, polymer with 1-ethenyl-2-
Methyltetrahydrophthalic anhydride
2,5-Furandione, polymer with ethenylbenzene, potassium sal
ETHYLENE-MALEIC ANHYDRIDE COPOLYMER,
Sodium azide
Dimethyltin-bis(isooctylthioglycolate)
octylphenol, diethoxy-
octylphenol, monoethoxy-
Dichloropropane
Triforine
Pseudomethylionone
POLY(ACRYLONITRILE-CO-ITACONICACID-CO-
POLY(ETHYLENE-CO-ITACONIC ACID)
Nominated
































Yes































































Draft
PCCL3














































Yes














Yes














Yes










Yes








Final
PCCL3














































Yes














Yes














Yes










Yes








Draft
CCL 3












































































Yes



















Public
Comment
































Yes































































Final
CCL 3












































































Yes



















CCL 2
































































































CCL1
































































































        A5-52

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
26713166
26713188
26741537
26750505
26760714
26761400
26761455
26762936
26796758
26837569
26877816
26896208
26916041
26936301
26952216
27012620
27013010
27056628
27074039
27090637
27107897
27157944
27176870
27178161
27193288
27193868
27196005
27205998
27215107
27215958
27247967
27304138
27314132
27344418
27458920
27496828
27554263
27636824
27774136
27791599
27813021
27902245
27939602
27955948
28005745
28057489
28064246
28108998
28109004
28140605
28178429
28231030
28249776
28299414
28302365
28377448
28407376
28434017
28553120
28575737
28629665
28693007
28729546
28772567
28777982
28790865
28801696
28805585
28826097
28829585
28984896
29014504
29082744
29122687
29160132
29222397
29224553
29232937
29383537
29385431
29408671
29534405
29560585
29590429
29611038
29612575
29761215
29911271
29911282
29964849
30007477
30105012
30125474
30177345
30207988
30228069
Common Name
2-Propenoic acid, polymer with chloroethene and ethene
2-Propenoic acid, polymer with ethene and ethenyl acetate
Bis(2,4-di-tert-butylphenyl)pentaerythritol diphosphite
Ethene, 1 ,1'-[oxybis(methylenesulfonyl)]bis-
DIHYDROABIETYL PHTHALATE
Diisodecyl phthalate
Neodecanoic acid, oxiranylmethyl ester
Hydroperoxide, bis(1-methylethyl)phenyl
Ethanaminium, N,N-diethyl-N-methyl-2-[(1-oxo-2-
POLY(MALEIC AN HYDRIDE-CO- VI NYL PYRROLIDONE)
2-Butenedioic acid (2E)-, polymer with ethene
Neodecanoic acid
2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, polymer
2-Propenoic acid, 2-methyl-, methyl ester, polymer with 3-
Isooctanol
2-Propenoic acid, methyl ester, polymer with 1 ,3-butadiene
Urea, polymer with ethanedial and formaldehyde
Polydimethylvinylpyridinium
1,4-Dimethyl-3-cyano-6-hydroxypyrid-2-one
1 ,6-Hexanediamine, N,N,N',N'-tetrabutyl-
Octyltintris(2-ethylhexyl mercaptoacetate)
O,O-Ditolyl phosphorodithioate
Dodecylbenzenesulfonic acid
Diisodecyl adipate
(1 ,1 ,3,3-Tetramethylbutyl)phenol
Dodecylphenol
Tetradecanol
Sodium O,O-diisopropyl dithiophosphate
Phosphoric acid, diisooctyl ester
Nonene
Nitric acid, 2-ethylhexyl ester
Oxychlordane
Norflurazon
Disodium 4,4'-bis(2-sulfostyryl)biphenyl
Isotridecanol
Benzole acid, methylenebis[2-hydroxy-
Diisooctyl phthalate
2,4-lmidazolidinedione, (hydroxymethyl)-5,5-dimethyl-
Vanadyl sulfate
2-Propenoic acid, polymer with N,N'-methylenebis[2-
Hydroxypropyl methacrylate
Glyceryl diricinoleate
3-Cyclohexene-1-carboxaldehyde, dimethyl-
Phenol, 4,4',4"-ethylidynetris-
Ethanol,2,2'-[(2-methylphenyl)imino]bis-
d-trans-Allethrin
POLY(ETHYLENE-CO-MALEIC ANHYDRIDE-CO- VINYL
Isopropylphenyl diphenyl phosphate
Bis(isopropylphenyl) phenyl phosphate
N-(3-Phenylimino-1-propenyl)aniline hydrochloride
Benzene, 2-isocyanato-1 ,3-bis(1-methylethyl)-
Cedr-8(15)-en-9-ol(8CI)
Thiobencarb
Benzene, 1,1'-oxybis[methyl-
Sodium copper chlorophyllin
2-Propenoic acid, 2-methyl-, polymer with ethenylbenzene, 2-
C.l. Direct Blue 218
Bioresmethrin
Diisononyl phthalate
POLY(DIALLYL PHTHALATE-CO-VINYL ACETATE)
Zinc O,O-diisooctyl dithiophosphate
Bicyclo(2.2.1)hept-5-en-2ylmethyl chloroacetate
Benzene, Methylpropyl
Bromadiolone
2,5-Furandione, dihydro-S-(octadecenyl)-
2,3,4-Trimethylcyclopent-2-en-1-one
Stannane, tributyl[(1-oxoneodecyl)oxy]-
Butanedioic acid, octenyl-
POLY(MONOETHYL MALEATE-CO-VINYL CHLORIDE)
POLY(1-BUTENE-CO-ETHYLENE-CO-1-OCTENE)
1,1'-Biphenyl, phenoxy-
POLY(BUTYL METHACRYLATE-CO-1-VINYL-2-
Octachlorostyrene
Atenolol
1-Butene, polymer with 1-propene
Biphenyltriol
Benzene, ethyldimethyl-
Pirimiphos-methyl
Butanedioic acid, methylene-, polymer with 1,3-butadiene,
1 H-Benzotriazole, 4(or 5)-methyl-
Nonanedioic acid, polymer with 1 ,2-propanediol
2-Butenedioic acid (2E)-, polymer with 1,3-butadiene,
Moricizine hydrochloride
Isooctyl acrylate
Aflatoxicol
POLY(2-HYDROXYETHYLMETHACRYLATE-CO-N-
Phosphoric acid, isodecyl diphenyl ester
2-Propanol, 1-(1-methyl-2-propoxyethoxy)-
2-Propanol, 1-(2-butoxy-1-methylethoxy)-
2-Propenoic acid, 2-methyl-, isodecyl ester
1 ,3-Dioxane, 5-bromo-5-nitro-
DIMETHYL-ALPHA-METHYLSTYRENE
C.I. Pigment Yellow 138
2-Propenoic acid, 2-methyl-, polymer with 1,1-dichloroethene
Undecanol
1 ,3-Propanediol, 2-ethyl-2-(hydroxymethyl)-, polymer with 5-
Nominated
























Yes

































Yes





































Draft
PCCL3






















Yes









Yes























Yes


























Yes












Final
PCCL3






















Yes









Yes























Yes


























Yes












Draft
CCL 3
































































































Public
Comment
























Yes

































Yes














Yes






















Final
CCL 3
































































































CCL 2
































































































CCL1
































































































        AS-53

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
30260721
30388013
30399849
30402143
30402154
30516871
30525894
30558431
30560191
30621591
30638085
30674807
30812874
30947309
31132306
31188917
31218834
31286881
31375174
31482561
31512740
31570044
31669553
31694163
31810896
31833611
31906044
31962944
31972437
31972448
31989216
32210234
32222063
32231508
32432556
32509663
32534819
32535845
32536520
32582744
32582755
32588548
32588764
32598133
32647679
32687788
32760808
32774166
32815966
32900064
33059051
33089611
33213659
33229344
33419420
33619920
33663502
33693048
33734575
33791581
33820530
33857260
34014181
34077877
34137092
34256821
34323541
34590948
34619299
34689468
34970008
35074772
35097177
35121789
35203066
35203088
35367385
35400432
35541812
35554440
35572782
35632996
35641384
35641599
35691657
35693993
35822469
35828785
35958306
36089073
36306873
36355018
36362977
36411526
36443682
36483575
Common Name
Benzenesulfonic acid, dodecyl(sulfophenoxy)-
2-Hydroxypropyl methanethiosulfonate
Isooctadecanoic acid
Tetrachlorodibenzofuran
Pentachlorodibenzofuran
ZIDOVUDINE
Paraformaldehyde
Oxamyl oxime
Acephate
POLY((1,3-DIBUTYLDISTANNTHIANEDIYLIDENE)- 1,3-
Cobalt phthalocyaninesulfonate
Methaciyloyloxyethyl isocyanate
Benzene, dibromoethyl-
Irgastab 2002 HT
2-Propenoic acid, polymer with N-[(dimethylamino)methyl]-2-
Component 3P-24
Propetamphos
2,5-Furandione, polymer with 2,2-bis(hydroxymethyl)-1,3-
2-Propionyl-6-menthene
Disperse orange 25
Poly(oxyethylene(dimethyliminio)ethylene(dimethyliminio)eth^
Tris(2,4-di-tert-butylphenyl) phosphite
Benzene, ethenyl-, polymer with 1,3-butadiene and 1,1-
POLY(P-OXYPHENYLENE P-OXYPHENYLENE P-
C.l. Disperse Blue 56
POLY(1 ,4-PHENYLENE SULFONE)
Lyral
Methyldigoxin
Fenamiphos sulfoxide
Fenamiphos sulfone
VINYL ACETATE-MALEIC ANHYDRIDE COPOLYMER,
Cyclohexanol, 4-(1,1-dimethylethyl)-, acetate
1,25-DIHYDROXYCHOLECALCIFEROL
2-Methylbutanoic acid
Benzenesulfonic acid, 3,5-diamino-2,4,6-trimethyl-
Ethylene bis(3,3-bis(3-tert-butyl-4-hydroxyphenyl)butyrate)
Pentabromodiphenyl ethers
Zirconyl ammonium carbonate
Benzene, 1,1'-oxybis-, octabromo deriv.
UNDECAFLUOROCYCLOHEXANEMETHANOL
UNDECAFLUOROCYCLOHEXANEMETHANOL
9,10-Anthracenedione, 2-(1,1-dimethylpropyl)-
Ethylene bis(tetrabromophthalimide)
3,3',4,4'-Tetrachlorobiphenyl
D-Glucitol, bis-O-(phenylmethylene)-
Bis(3,5-di-tert-butyl-4-hydroxyhydrocinnamoyl)hydrazine
lron(1+), (.eta.5-2,4-cyclopentadien-1-yl)[(1,2,3,4,5,6-.eta.)-(1
3,3',4,4',5,5'-Hexachlorobiphenyl
2-NITROBUTYL BROMOACETATE
Thiourea, N-butyl-N'-ethyl-
2-Hydroxy-4-isooctoxybenzophenone
Amitraz
.beta.-Endosulfan
HC Blue no. 2
Etoposide
Sodium di-sec-butyl phosphorodithioate
Benzenamine, 2,4,6-trichloro-, hydrochloride
Terbumeton
PEROXYOCTANOIC ACID
Dicyclopentadiene acrylate
Isopropalin
2,7-Dichlorodibenzo-p-dioxin
Tebuthiuron
Dichlorotrifluoroethane
Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy
Acetochlor
POLY(ETHYL ACRYLATE-CO-MALEIC ANHYDRIDE- CO-
Dipropylene glycol monomethyl ether
Bromodichloroacetaldehyde
Sodium cresolate
Methane, bromochloroiodo-
Irganox 249
DIETHYLENE GLYCOL COPOLYMER OF ADIPIC ACID
Epoprostenol
Benzenamine, 2-ethyl-6-methyl-N-methylene-
Benzenamine, 2,6-diethyl-N-methylene-
Diflubenzuron
Sulprofos
1 ,4-Cyclohexanedimethanol, dibenzoate
Imazalil
2-Amino-4,6-dinitrotoluene
Blankophore P fluessig
POLY(ACRYLONITRILE-CO-BUTADIENE-CO- METHYL
1-Propanesulfonic acid, 2-methyl-2-[(1-oxo-2-
Bromothalonil
2,2',5,5'-Tetrachlorobiphenyl
1,2,3,4,6,7,8-Heptachlorodibenzo-p-dioxin
2-Propenoic acid, ethyl ester, polymer with 1,1-
2,2'-Ethylidenebis(4,6-di-tert-butylphenol)
POLY(ACRYLONITRILE-CO-BUTADIENE-CO-2-
3,3,5,5-Tetramethyl-4-ethoxyvinylcyclohexanone
1 ,1'-Biphenyl, hexabromo-
1 ,2,3-Benzenetricarboxylic acid
Benzamide, 2-hydroxy-N-1 H-1 ,2,4-triazol-3-yl-
Benzenepropanoic acid, 3-(1 ,1-dimethylethyl)-4-hydroxy-5-
2,2-Dimethyl-1-propanol, tribromo deriv.
Nominated
































































































Draft
PCCL3








Yes



























Yes














Yes










Yes


Yes











Yes


















Final
PCCL3








Yes



























Yes














Yes










Yes


Yes











Yes


















Draft
CCL 3








Yes
























































Yes






























Public
Comment




Yes
























Yes



































Yes




Yes















Yes









Final
CCL 3








Yes
























































Yes






























CCL 2

































































Yes






























CCL1

































































Yes






























        AS-54

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
36483600
36653824
36727294
36734197
36768624
36876138
37148279
37189836
37199669
37281531
37319178
37625755
37626156
37677148
37764253
37853591
37890281
38103069
38193601
38285493
38413820
38613773
38615439
38640629
38641940
38720615
38721710
38727558
38812929
38820596
38916426
38998753
39001020
39148248
39156417
39195829
39196184
39227286
39236469
39275633
39296305
39300453
39300884
39346764
39443760
39515418
39515510
39638329
40088479
40292828
40321764
40487421
40596698
40843252
40876980
40880511
41096462
41098560
41171146
41198087
41294568
41372081
41484359
41525411
41638135
41663847
41851507
41903575
42125462
42373046
42399417
42874033
42978665
43094662
43121433
43222486
44914036
47465974
48240251
49690940
50327225
50471448
50594666
50594779
50867602
50892234
51000523
51026289
51053282
51162517
51207319
51218452
51235042
51264143
51287844
51333223
Common Name
Benzene, 1,1'-oxybis-, hexabromo deriv.
1-Hexadecanol
Hexanoyl chloride, 3,5,5-trimethyl-
Iprodione
4-Piperidinamine, 2,2,6,6-tetramethyl-
1,1'-Biphenyl,ar,ar'-bis(1-methylethyl)-
Clenbuterol
9,12-Octadecadienoic acid (9Z,12Z)-, dimer, polymer with N-
Potassium polysulfide
Starch, polymer with formaldehyde and urea
ELMIRON (SODIUM PENTOSANPOLYSULFATE)
BETA-3(OR 4)-
POLY(ACRYLONITRILE-CO-BUTADIENE-CO-2-
1-Formyl-4-isohexenyl-4-cyclohexene
Acetamide, 2,2-dichloro-N,N-di-2-propenyl-
1 ,2-Bis(2,4,6-tribromophenoxy)ethane
2-Propen-1-amine, N-methyl-N-2-propenyl-, polymer with
1 ,3-lsobenzofurandione, 5,5'-[(1-methylethylidene)bis(4,1-
1-Propanesulfonic acid, 2-methyl-2-[(1-oxo-2-
2H-Pyran-4-ol, 3-butyltetrahydro-5-methyl-, acetate
BIS(METHOXYMETHYL)TETRAKIS((OCTADECYLOXY
Irganox P-EPQ
1 ,6-Hexanediamine, N-butyl-
Diisopropylnaphthalene
Glyphosate isopropylamine salt
ALPHA-(CARBOXYMETHYL)-OMEGA-
Benzene, dichloro(chloromethyl)-
Diethatyl ethyl
2-Propenoic acid, polymer with (chloromethyl)oxirane, 1,1'-
Dequest 2054 deflocculant and sequestrant
Alcopol R 540
Heptachlorodibenzofuran
1,2,3,4,6,7,8,9-Octachlorodibenzofuran
Fosetyl-AI
1,3-Benzenediamine, 4-methoxy-, sulfate (1:1)
2-Butanone, 3,3-dimethyl-1-(methylthio)-, oxime
Thiofanox
1 ,2,3,4,7,8-Hexachlorodibenzo-p-dioxin
Imidurea
FUMARATOCHROMIUM(III) NITRATE
POLY(ACRYLAMIDE-CO-(2-
Dinocap
Tara gum
Guar gum, carboxymethyl ether, sodium salt
Benzenesulfonic acid, 2,4-diamino-, calcium salt (2:1),
Fenpropathrin
Benzaldehyde, 3-phenoxy-
Bis(2-chloroisopropyl) ether
Benzene, 1,1'-oxybis-, tetrabromo deriv.
Neodecanoyl chloride
1,2,3,7,8-Pentachlorodibenzo-p-dioxin
Pendimethalin
Methoprene
Diclofop
Diethyl sodium oxalacetate
Disperse Red Polyester
Hydroprene
Tinopal CH 3669
2-Propenoic acid, ethyl ester, polymer with ethene and 2,5-
Profenofos
Alphacalcidol
alpha-Methyldopa sesquihydrate
Irganox 1035
2-Propenoic acid, polymer with ethene and methyl 2-
Dipropylene glycol diglycidyl ether
1 H-lsoindole-1 ,3(2H)-dione, 2-methyl-5-nitro-
1 ,3-Cyclopentadiene, 5-chloro-
Tetrachlorodibenzo-p-dioxin
4-tert-Butylcyclohexyl chloroformate
C.I. Basic Red 29
diltiazem
Oxyfluorfen
Tripropylene glycol diacrylate
POLY(ACRYLONITRILE-CO-VINYLSTEARATE)
Triadimefon
Difenzoquat methyl sulfate
2-Methylbutyl acrylate
Isatin biscresol
P,P'-BIS(UNDECAFLUOROCYCLOHEXANEMETHANOL)
Benzene, 1,1'-oxybis-, tribromo deriv.
NYLON 46
Vinclozolin
Acifluorfen
2-Chloro-4-trifluoromethyl-3'-acetoxydiphenyl ether
POLY(ACRYLONITRILE-CO-METHYL VINYL ETHER)
Pirinixic acid
Neodecanoic acid, ethenyl ester
Potassium (hydroxymethyl)methyldithiocarbamate
DINITROBUTYL PHENOL
O-Ethyl O-isopropyl phosphorochloridothioate
2,3,7,8-Tetrachlorodibenzofuran
Metolachlor
Hexazinone
AMSACRINE
Stannane, bis(dodecylthio)dimethyl-
Budesonide
Nominated






































































Yes




















Yes




Draft
PCCL3



























































Yes











Yes



Yes





Yes









Yes




Final
PCCL3



























































Yes











Yes



Yes





Yes









Yes




Draft
CCL 3



























































Yes











Yes









Yes









Yes




Public
Comment































Yes
Yes





































Yes



















Yes
Yes




Final
CCL 3



























































Yes











Yes









Yes









Yes




CCL 2



























































































Yes




CCL1



























































































Yes




        AS-55

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
51338273
51363645
51481619
51630581
51632167
51678730
51706106
51707552
51733109
51959149
51995621
52007224
52315078
52411333
52572380
52628258
52645531
52663726
52829079
52831046
52907070
52918635
53123845
53378511
53378715
53404196
53469219
53626532
53744506
53850343
53956040
53988106
54024225
54150695
54333754
54453031
54471986
54546268
54593838
54686974
54688549
54749905
54774457
54849386
54910893
54982831
55219653
55283686
55285148
55290647
55335063
55406536
55512339
55556928
55557001
55566308
55673897
55684941
55799161
55852841
55854336
55984515
56011020
56046629
56070156
56070167
56073100
56425913
56539663
56750766
56803373
56831620
57018049
57018527
57057837
57116457
57117314
57117416
57213691
57282492
57378684
57472681
57497297
57583343
57583354
57609640
57673140
57673151
57754855
57801817
57837191
57966957
58138082
58240576
58430947
58446529
Common Name
Diclofop methyl
Phosphoric acid, diisodecyl phenyl ester
Cimetidine
Fenvalerate
Benzene, 1-(bromomethyl)-3-phenoxy-
2-HYDROXYETHANESULFONIC ACID MALEATE,
DIPHENYL 1,3-BENZENEDICARBOXYLATE- DIPHENYL
Thidiazuron
Dodecanedioic acid, polymer with hexahydro-2H-azepin-2-
4-(2,4-Di-t-pentylphenoxy)butylamine
NYLON 6/69 RESINS
POLY(HEXAM ETHYL ENEDIAMINE AZ ELATE)
Cypermethrin
Benzenamine, 2,2'-[1 ,2-ethanediylbis(thio)]bis-
4-Diazo-2-methylpyrrolidinobenzene zinc chloride
Zinc ammonium chloride
Permethrin
2,3',4,4',5,5'-Hexachlorobiphenyl
Bis(2,2,6,6-tetramethyl-4-piperidinyl) sebacate
2-Propenoic acid, polymer with ethenylbenzene and (1-
Saytex BN 451
Deltamethrin
Starch, acetate, ether with 1,2,3-propanetriol (2:1)
Sodium diisobutyldithiophosphate
Dispiro[cyclohexane-1,2'(3'H)-quinazoline-4'(4'aH),1"-
Bromacil, lithium salt
Aroclor1242
POLY(2-HYDROXYETHYL METHACRYLATE-CO- METHYL
Benzenemethanol, 4-(acetyloxy)-.alpha.-methyl-
Proteins, thaumatins
Ammonium glycyrrhizate
2-Mercaptomethylbenzimidazole
DESOGESTREL
Benzenamine, 2,4-dimethoxy-, hydrochloride
Propanamide, 2-chloro-N,N-diethyl-
Copper ethylenediaminetetraacetate
POLY(N-METHYLDIMETHACRYLAMIDE- CO-METHYL
1 ,3-Dioxane, 2-butyl-4,4,6-trimethyl-
Chlorethoxyfos
DI-P-TOLYLIDENE SORBITOL
PHENOL-COUMARONE-INDENE RESIN
Chlorozotocin
Cis- Permethrin
Methyltin tris(isooctyl thioglycolate)
FLUOXETINE
1 ,4-Dioxacyclohexadecane-5,16-dione
Triadimenol
Ethalfluralin
Carbosulfan
Dimethipin
Triclopyr
3-lodo-2-propynyl butylcarbamate
Pyridate
Nitroso-1 ,2,3,6-tetrahydropyridine
1 H-1 ,4-Diazepine, hexahydro-1 ,4-dinitroso-
Tetrakis(hydroxymethyl)phosphonium sulfate
1,2,3,4,7,8,9-Heptachlorodibenzofuran
Hexachlorodibenzofuran
ZINC HYDROXY PHOSPHITE
Bacitracin methylenedisalicylic acid
2-Propenoic acid, 2-methyl-, polymer with butyl 2-methyl-2-
N-Nitrosomethyl(2-oxopropyl)amine
Benzene, [2-(3-methylbutoxy)ethyl]-
Methanesulfonamide, N-[2-[ethyl(3-methyl-4-
Terbufos-O-analogue sulfone
Terbufos sulfone
Brodifacoum
Flurprimidol
1-Butanol, 3-methoxy-3-methyl-
4-(Hydroxymethyl)pendimethalin
tert-Butylphenyl diphenyl phosphate
1-Tridecanol, phosphate
Tolclofos-methyl
Propylene glycol mono-t-butyl ether
3,4,5-Trichloroguaiacol
Pentaerythritol-tris-(beta-(N-aziridinyl)propionate)
2,3,4,7,8-Pentachlorodibenzofuran
1,2,3,7,8-Pentachlorodibenzofuran
Triclopyr-triethylammonium
L-Lysine, monoacetate
8-Damascone
Dipropylene glycol diacrylate
Z-Ethyl-O,N,N-azoxymethane
8-Oxa-3,5-dithia-4-stannatetradecanoic acid, 10-ethyl-4-[[2-
Tin, methyl-, tris(isooctyl thioglycollate)
1 ,3-Propanediol, bis(4-aminobenzoate)
Butanedioic acid, methylene-, polymer with ethyl 2-
POLY(ETHYL ACRYLATE-CO-ITACONIC ACID-CO- N-
Clopyralid-olamine
Brotizolam
Metalaxyl
Cymoxanil
Tridiphane
2-Ethylhexyl (3-isocyanatomethylphenyl) carbamate
1-Hexanol, 3,5,5-trimethyl-, acetate
1 ,3-Eicosanedione, 1-phenyl-
Nominated












































Yes





Yes













































Draft
PCCL3












Yes



Yes





















Yes










Yes














Yes
Yes







Yes






















Final
PCCL3












Yes



Yes





















Yes










Yes














Yes
Yes







Yes






















Draft
CCL 3
















Yes
































Yes















Yes






























Public
Comment


Yes









































Yes











Yes



















Yes
Yes


















Final
CCL 3
















Yes
































Yes















Yes






























CCL 2
































































































CCL1
































































































        AS-56

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
58639864
58958604
59230578
59337938
59419602
59487239
59669260
59756604
59766313
59808785
59820438
59858503
59865133
59911523
60015056
60168889
60207901
60238564
60523731
60568050
60676860
60851345
61167586
61260557
61262531
61470335
61617003
61699385
61702430
61702441
61788327
61788725
61789364
61789513
61791182
61949766
61949777
62362496
62476599
62924703
63134292
63148594
63148629
63397604
63405856
63438802
63734623
63843890
63905293
63936561
63938103
64051394
64091914
64253301
64257847
64265572
64285069
64359815
64502132
64536067
64652604
64742456
64902723
65045763
65140912
65195553
65212773
65232895
65379320
65405632
65405778
65442311
65646686
65652417
65666071
65997173
66070584
66070595
66070619
66215278
66230044
66327546
66332965
66357355
66441234
66822604
66841256
67035227
67338629
67485294
67562394
67634155
67649654
67747095
67845936
67893532
Common Name
2-Propenoic acid, polymer with ethyl 2-propenoate and (1-
Propanoic acid, 2,2-dimethyl-, isooctadecyl ester
Benzenemethanol, 4-(1-methylethyl)-, acetate
Methyl 3-(aminosulfonyl)-2-thiophenecarboxylate
Starch, polymer with (chloromethyl)oxirane and
C.I. Pigment Red 187
Thiodicarb
Fluridone
Potassium titanium oxide
Cyclopentane, tetrachloro-
HC yellow 4
2-Propenoic acid, 2-methyl-, methyl ester, polymer with 1 ,3-
Cyclosporin A
POLY(ACRYLICACID-CO-ACRYLONITRILE-CO-
POLY(OXY-1 ,4-PHENYLENECARBONYL-1 ,4-
Fenarimol
Propiconazole
Chlorthiophos
Bromodichloroacetonitrile
Furmecyclox
Silica, vitreous
2,3,4,6,7,8-Hexachlorodibenzofuran
2-Propenoic acid, 2-(1,1-dimethylethyl)-6-[[3-(1,1-
1 ,6-Hexanediamine, N,N'-bis(2,2,6,6-tetramethyl-4-
1,2-Bis(pentabromophenoxy)ethane
Bis(beta-carbobutoxyethyl)tin dichloride
Methyl-2-mercaptobenzimidazole, zinc salt
Carbonic acid, cyclooctyl methyl ester
Phenol, 2-amino-4-nitro-, monosodium salt
1 ,4-Benzenediamine, 2-chloro-, sulfate (1:1)
Terphenyl, hydrogenated
Fatty acids, tall-oil, epoxidized, octyl esters
Naphthenic acids, calcium salts
Cobalt naphthenate
Alcohols, rosin, ethoxylated
cis-Permethrin
trans-permethrin
Poly(oxy-1 ,2-ethanediyl), .alpha.-octadecyl-.omega.-hydroxy-
Acifluorfen, sodium salt
Flumetralin
Butanamide, 4-[2,4-bis(1,1-dimethylpropyl)phenoxy]-N-(4-
Siloxanes and Silicones, di-Ph
Siloxanes and Silicones, di-Me
Bis-beta-carbobutoxyethyltin bisisooctylthioglycolate
Benzenesulfonic acid, 3-[[3-methoxy-4-[(4-
Propanoic acid, 3-[tris[[2-(isooctyloxy)-2-oxoethyl]thio]stannyl
Benzole acid, 3-[2-chloro-4-(trifluoromethyl)phenoxy]-
Tinuvin 144
Bis(3-cyclohexenylmethyl) adipate
Benzene, pentabromo(tetrabromophenoxy)-
Chlorotetrafluoroethane
Phenol, dipentyl-, dihydrogen phosphate
1-Butanone, 4-(methylnitrosoamino)-1-(3-pyridinyl)-
Propanoic acid, S-(dodecylthio)-, oxybis(2,1-ethanediyloxy-
Fenpropathrin
Trimethylolpropane, tris(3-(2-methylaziridinyl)propanoate)
Anatoxin-a
3(2H)-lsothiazolone, 4,5-dichloro-2-octyl-
Poly(oxy-1 ,2-ethanediyl), .alpha. ,. alpha.',. alpha. "-
Benzene, ethenyl-, polymer with 1-methyl-4-(1-
2-Propenoic acid, butyl ester, polymer with ethene and 2,5-
Distillates, petroleum, clay-treated light naphthenic
Chlorsulfuron
2-Propenoic acid, polymer with chloroethene, 1,1-
Ethyl 3,5-di-tert-butyl-4-hydroxybenzylphosphonate, calcium
Avermectin A1 a, 5-O-demethyl-
C.l. Pigment Yellow 183
Vanadium hydroxide oxide phosphate
POLY(ACRYLAMIDE-CO-N-METHYLOACRYLAMIDE-CO-
2-Propenoic acid, 2-methyl-, polymer with ethenylbenzene,
Benzole acid, 2-hydroxy-, (3Z)-3-hexenyl ester
6-sec-Butylquinoline
4-(HYDROXYPHENYL)RETINAMIDE
Bis(t-butylphenyl) phenyl phosphate
PREVENTION 2 (SILYMARIN)
Glass, oxide, chemicals
Benzene, ethenyl-, polymer with 1,3-butadiene, hydrogenatec
Linseed oil, polymer with glycerol and phthalic anhydride
Soybean oil, polymer with glycerol and phthalic anhydride
Cyromazine
Esfenvalerate
Vernaldehyde
Flutolanil
RANITIDINE
Fenoxaprop-ethyl
POLY(CYCLOHEXYL METHACRYLATE-CO-ETHYL
Tralomethrin
dehydronifedipine
Acetamide, N-[5-[ethyl(phenylmethyl)amino]-2-[[5-(ethylthio)-
Hydramethylnon
1,2,3,4,6,7,8-Heptachlorodibenzofuran
Benzenepropanal, 4-ethyl-. alpha.,. alpha. -dimethyl-
N-DODECYLTINS,S",S"-
Prochloraz
Benzole acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-,
Hexanedioic acid, polymer with 1 ,4-butanediol, 1 ,2-ethanedio
Nominated




































Yes



















Yes


























Yes



Yes








Draft
PCCL3






Yes

















































Yes






















Yes
Yes





Yes









Final
PCCL3






Yes

















































Yes






















Yes
Yes





Yes









Draft
CCL 3






Yes

















































Yes







































Public
Comment












Yes





Yes





































Yes


























Yes



Yes


Yes





Final
CCL 3






Yes

















































Yes







































CCL 2
































































































CCL1
































































































        A5-57

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
68002186
68002255
68015781
68037398
68037570
68083181
68083192
68085858
68123240
68130712
68131044
68141173
68152614
68170592
68186801
68186903
68186914
68189231
68227010
68239996
68258913
68259052
68334678
68359375
68424044
68425025
68441145
68441372
68442682
68457749
68479981
68492728
68515888
68553082
68554701
68555862
68583799
68584907
68605414
68683205
68908872
68915311
68937406
68937417
68955544
68987600
68988761
69116718
69327760
69335917
69409945
69655056
69806402
69806504
69851612
69852455
70025002
70142346
70321867
70331941
70458967
70560155
70592802
70630170
70648269
70729689
70892216
70976975
71033084
71130546
71130604
71133147
71329505
71519807
71751412
71786602
71786704
72102842
72178020
72275684
72490018
72850647
72918219
72968424
73070378
73334073
73347805
73506942
74051802
74115245
74222972
74223566
74223646
74263539
74263540
74441057
Common Name
Urea, polymer with formaldehyde, isobutylated
1 ,3,5-Triazine-2,4,6-triamine, polymer with formaldehyde,
Nitrilotriacetic acid ammonium zinc salt
Ethene, homopolymer, chlorinated, chlorosulfonated
Silicic acid, 2-ethylbutyl ester
Siloxanes and Silicones, di-Me, Me vinyl, vinyl group-
Siloxanes and Silicones, di-Me, vinyl group-terminated
Cyhalothrin
2-Propenoic acid, 2-methyl-, 1,2-ethanediyl ester, polymer
Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-. omega. -hydroxy-,
Humic acids, sodium salts
Undecane, 1,1-dimethoxy-2-methyl-
Rosin, maleated, polymer with bisphenol A, formaldehyde
Octadecanoic acid, 9(or 10)-(sulfooxy)-
Guargum, 2-(diethylamino)ethyl ether, hydrochloride
C.I. Pigment Brown 24
C.I. Pigment Black 28
Benzaldehyde, 4-(diethylamino)-, diphenylhydrazone
2-Propenoic acid, 2-methyl-, butyl ester, polymer with
4,7-Methano-1 H-indene, 3a,4,7,7a-tetrahydro-, polymer with
Cyclopentane, hexachloro-
Benzoic acid, 3,3'-[(2,5-dimethyl-1,4-
1 ,1 ,2,3,4-Pentachloro-4-(isopropoxy)buta-1 ,3-diene
Cyfluthrin
POLYDEXTROSE
Resin acids and Rosin acids, hydrogenated, zinc salts
1,3-Butadiene, 2-methyl-, polymer with 2-methyl-1-propene,
Benzene, ethenyl-, polymer with (l-methylethenyl)benzene,
Benzenamine, N-phenyl-, styrenated
Phenol, isobutylenated methylstyrenated
Diethyltoluenediamine
1 ,3-Benzenedicarboxylic acid, polymer with 2,2-dimethyl-1 ,3-
Pentene, 2,4,4-trimethyl-, sulfurized
Glycerides, tallow di-
Silsesquioxanes, Me
Benzenesulfonic acid, 4-[[5-methoxy-4-[(4-
Hexanedioic acid, polymer with N-(2-aminoethyl)-1 ,2-
Starch, reaction products with formaldehyde
Fatty acids, tall-oil, polymd., Me esters
1 ,?-Cyclohexadiene-1-ethanol, 4-(1-methylethyl)-, formate
Benzene, 1,3-dimethyl-, benzylated
Polyphosphoric acids, sodium salts
Isobutylenated phenol phosphate (3:1)
Isopropylated phenol phosphate (3:1)
Amines, C16-22-tert-alkyl
Calcium, polymd. resin acids and tall-oil fatty acids
9-Octadecenoic acid (9Z)-, sulfonated
Propanoic acid, 2,2,3-trifluoro-3-oxo-, methyl ester
Buprofezin
FLUAZIFOP
Fluvalinate
DIDEOXYINOSINE
Haloxyfop-methyl
Fluazifop-butyl
Benzenepropanamide, N,N'-1 ,3-propanediylbis[3,5-bis(1 ,1-
Propanenitrile, 3-[[3-(dimethylamino)propyl]amino]-
Fatty acids, C18-unsatd., trimers, Me esters
Octadecanoic acid, 12-hydroxy-, polymerwith .alpha.-hydro-
Phenol,2-(2H-benzotriazol-2-yl)-4,6-bis(1-methyl-1-
Naugard XL-1
norfloxacin
POLY(MONOMETHYL MALEATE-CO- VINYL CHLORIDE)
Amines, C10-16-alkyldimethyl, N-oxides
Metalaxyl-M
1,2,3,4,7,8-Hexachlorodibenzofuran
Tetraethylene glycol di-n-heptanoate
Acetic acid ethenyl ester, polymerwith ethenol, reaction
POLY(BUTYL ACRYLATE-CO-ETHYLENE-CO-
2,2-Bis(p-(2-glycidyloxy-3-butoxypropyloxy)phenyl)propane
Phenyl p-cyanophenylcarbamate
Phenol, 2-[(ethylamino)methyl]-4-nitro-
Bromodichloroacetic acid
Guar gum, 2-hydroxypropyl 2-hydroxy-3-
1 ,3-Benzenedicarbonyl dichloride, polymerwith 1,4-
Abamectin
Ethanol, 2,2'-iminobis-, N-C12-18-alkyl derivs.
lodonium, bis(4-dodecylphenyl)-, (OC-6-11)-
2,4,6(1 H,3H,5H)-Pyrimidinetrione, 5-[(2,3-dihydro-6-methyl-2-
Fomesafen
POLY(ACRYLAMIDE-(2-ACRYLAMIDE-2-
Fenoxycarb
Flurazole
1,2,3,7,8,9-Hexachlorodibenzofuran
GENTIAN ROOT, EXTRACT (GENTIANA LUTEA L.)
Phyton-27
lopromide
9,10-Anthracenediol, 1 ,4-dihydro-, disodium salt
Ethane, dibromochloro-
Sethoxydim
Clofentezine
Sulfometuron methyl
Sulfometuron
Metsulfuron-methyl
POLY(DIMETHYL-ALPHA-METHYLSTYRENE-CO-ALPHA-
POLY(DIMETHYL-ALPHA-METHYLSTYRENE-CO-ALPHA-
Benzamide, N-[4-(aminocarbonyl)phenyl]-4-[[1-[[(2,3-dihydro-
Nominated




























































Yes










Yes
























Draft
PCCL3























Yes






Yes











































Yes



Yes









Yes







Final
PCCL3























Yes






Yes











































Yes



Yes









Yes







Draft
CCL 3
































































































Public
Comment




























































Yes










Yes













Yes










Final
CCL 3
































































































CCL 2
































































































CCL1
































































































        AS-58

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
74782233
75147205
75411835
75519196
75980608
76420729
76543889
76578126
76578148
76738620
76774259
77182822
77352239
77402381
77439760
77501634
77732093
77804810
78491028
78587050
79217600
79277273
79277671
79510488
79538322
80214831
80693001
80844071
81334341
81335377
81335775
81405858
81777891
82097505
82558507
82657043
82697710
82985351
83015898
83044999
83055996
83463621
83905015
84030615
84087014
84632655
84852153
85209912
85509199
85721331
86803909
86954361
87365988
87547044
87674688
87820880
88485374
88671890
89365504
89911795
90498901
90982324
91465086
91648247
92177509
92265811
93106606
94125345
94270867
95617097
95737681
96182535
96489713
97953225
98036465
98105998
98967409
99283008
99283019
99316139
99387890
99422012
100728845
100784201
100897129
101043372
101200480
101229032
102322361
103361097
104098488
105035107
105442851
105607043
106040486
106107544
Common Name
Oxabetrinil
3-Butenoic acid, 2,2,3,4,4-pentachloro-, butyl ester
N-Nitrosomethyl-2-hydroxypropylamine
Acetonitrile, tribromo-
Phosphine oxide, diphenyl(2,4,6-trimetriylbenzoyl)-
enalaprilat
INTERFERONA(AIDS INITIATIVE)
Quizalofop
Quizalofop-ethyl
Paclobutrazol
POLY(ACRYLIC ACID-CO-SODIUM ACRYLATE-CO-
Glufosinate-ammonium
Bromochloroamine
POLYAMIDE POLYETHER BLOCK COPOLYMERS
3-Chloro-4-dicrilorometriyl-5-riydroxy-2-furanone
Lactofen
Oxadixyl
Butanamide, 2,2'-[1 ,2-ethanediylbis(oxy-2,1-
Diazolidinylurea
Hexythiazox
Cyclosporin
Thifensulfuron-methyl
Thifensulfuron
Metsulfuron
Tefluthrin
roxithromycin
2,4,8,10-Tetraoxa-3,9-diphosphaspiro[5.5]undecane, 3,9-
Etofenprox
Imazapyr
Imazaquin
Imazethapyr
Imazametriabenz-methyl
Clomazone
Triasulfuron
Isoxaben
Bifenthrin
Clofencet potassium
Bis(trimetrioxysilylpropyl)amine
Strontium-85
POLY(M-PHENYLENEDIAMINE-CO-TRIMESOYL
Bensulfuron-methyl
Bromochloroacetonitrile (BCAN)
azithromycin
DI(N-DODECYL)TIN S,S'-
Quinclorac
Pyrrolo[3,4-c]pyrrole-1 ,4-dione, 3,6-bis(4-chlorophenyl)-2,5-
Phenol, 4-nonyl-, branched
12H-Dibenzo[d,g][1,3,2]dioxaphosphocin,2,4,8,10-
Flusilazole
CIPROFLOXACIN
Scentenal
Americium, isotope of mass 241 (241Am3+)
POLY(1,3-BIS(2-HYDROXYETHOXY)BENZENE-CO-
FLUMICLORAC
Dimethenamid
Tralkoxydim
Fluxofenim
Myclobutanil
Salmeterol
Nitrosotrihydroxy-dipropylamine
Benzenepropanoic acid, 3-(1 ,1-dimethylethyl)-4-hydroxy-5-
Chlorimuron-ethyl
lambda-Cyhalothrin
1,3-Propanediol, 2,2-bis(hydroxymethyl)-, allyl ether
Nitroso-2,3-dihydroxypropyl-2-oxopropylamine
POLY(CHOLINE CHLORIDE METHACRYLATE-CO-2-
ENROFLOXACIN
Prosulfuron
1 H-Benzotriazole-1-methanamine, N,N-bis(2-ethylhexyl)-ar-
Fenoxaprop
Pyriproxyfen
Phostebupirim
Pyridaben
Alcohols, C>30, ethoxylated
STYRENE-MALEIC ANHYDRIDE COPOLYMER
SARAFLOXACIN
Flumetsulam
Chlorimuron
Bensulfuron
POLY(ACRYLAMIDOMETHYLPROPANESULFONICACID-
TRIFLUMIZOLE
1 ,3-Cyclohexanedione, 5-[2-(ethylthio)propyl]-2-(1-oxopropyl)
IMAZAMETHABENZ
Halosulfuron-methyl
AMMONIUM GLUCOHEPTONATE
Microcystin-LR
Tribenuron-methyl
N-ACETYL-N-(2-HYDROXYETHYL)-N'-
POLY(MALEIC ANHYDRIDE-CO-STYRENE-CO- VINYL
Flumioxazin
Imazapic
POLY(LIMONENE-CO-BETA-PINENE-CO-STYRENE)
BIS(BENZOATE-0)(2-PROPANOLATO)ALUMINUM
POLY(HYDROXYPROPYL ACRYLATE-CO-PEG-4
Tribenuron
STYRENE BLOCK POLYMERS WITH 1 ,3- BUTADIENE
Nominated





Yes








Yes










Yes















Yes







Yes
















Yes








Yes









Yes










Draft
PCCL3







Yes







Yes






Yes









Yes





























Yes






















Yes










Final
PCCL3







Yes







Yes






Yes









Yes








Yes




















Yes






















Yes










Draft
CCL 3





















































































Yes










Public
Comment



Yes

Yes








Yes










Yes















Yes
Yes






Yes




Yes











Yes








Yes









Yes










Final
CCL 3





















































































Yes










CCL 2
































































































CCL1
































































































        AS-59

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
106168369
106797539
106990436
107534963
107584407
109293972
110429624
110488705
110553270
111991094
112410238
113036876
113136779
113652565
113669582
114133447
114311329
114369436
114464652
115340675
115340777
116355830
116438563
116810470
117718602
118299904
118632181
118685260
118948859
119313121
120068373
120883672
121552612
121888673
121888684
122551897
122836355
122931480
123343168
123968252
125533882
126050542
126572803
127455441
127564925
128685994
128906365
129423547
130328244
131341861
131860338
131929607
132059519
132059520
132059531
134098616
134701205
135158542
135861562
135990293
138261413
141112290
142363539
142459583
143390890
143545908
144093889
144772394
145599866
145650608
146452939
147150354
147315502
149564625
149564636
149564647
150413266
151841655
152019733
161717324
166164745
167678435
171118095
171262172
173903156
175419235
183508181
184785384
184992444
187022113
192268647
192268658
193098407
378784226
378784248
378784453
Common Name
Benzene, ethenyl-, polymer with 1-methyl-4-(1-
Darocur 2959
TINUVIN770
Tebuconazole
Dimethylethyl Lead
Diflufenzopyr
Clethodim
Dimethomorph
Phenol, 2-methyl-4,6-bis[(octylthio)methyl]-
Nicosulfuron
Tebufenozide
PRIMISULFURON
Cyclanilide
1-OCTANESULFONIC-2-SULFINICACID
1 ,2-OCTANEDISULFONIC ACID
Hexanedioic acid, polymer with N-(2-aminoethyl)-1 ,3-
Imazamox
Fenbuconazole
POLY(2-HYDROXYETHYL ACRYLATE-CO- VINYLIDENE
(E)-3-Formyl-2,4,4-trichloro-2-butenoic acid
Hexanedioic acid, polymer with N-(2-aminoethyl)-1 ,2-
Fumonisin B1
N,N-BIS(HYDROGENATED TALLOW ALKYLj-2-
SILOXANES AND SILICONES, DIMETHYL, 3-
Thiazopyr
ETHANEDIAL, POLYMER WITH TETRAHYDRO-4-
SODIUMPOLY(ISOPROPENYLPHOSPHONATE)
POLY(DIETHANOLAMINE-CO-ISOBUTYLENE-CO- MALEIC
POLY(ACRYLICACID-CO-ACRYLONITRILE-CO-
1-Butanone, 2-(dimethylamino)-1-[4-(4-morpholinyl)phenyl]-2-
Fipronil
ROSIN, MALEATED METHYL AND ETHYLENE GLYCOL
Cyprodinil
Quaternary ammonium compounds, benzylbis(hydrogenated
Quaternary ammonium compounds, benzyl(hydrogenated
3-Chloro-4-(dichloromethyl)-2-(5H)-furanone
Sulfentrazone
Rimsulfuron
Pyrithiobac-sodium
2-Propenoic acid, 2-[1-[3,5-bis(1 ,1-dimethylpropyl)-2-
MOFAROTENE
12H-Dibenzo[d,g][1,3,2]dioxaphosphocin,2,4,8,10-
(E)-2-Chloro-3-(dichloromethyl)butenedioicacid
POLY(N,N'-BIS(3-AMINOPROPYL)ETHYLENEDIAMINE-
Dichloropentafluoropropane
ALPHA-OLEFI NS(C30+)
POLY(ETHYLACRYLATE-CO-FORMALDEHYDE-CO-
C.l. PIGMENT YELLOW 191
N,N,N',N',N",N"-HEXAKIS(METHOXYMETHYL)-1,3,5-
Fludioxonil
Azoxystrobin
Spinosyn A
(BMX-1)3-Chloro-4-(bromochloromethyl)-5-hydroxy-2(5H)-
(BMX-2)3-Chloro-4-(dibromomethyl)-5-hydroxy-2(5H)-
(BMX-3)3-Bromo-4-(dibromomethyl)-5-hydroxy-2(5H)-
Fenpyroximate
Phenol, 2, 4-dimethyl-6-(1-methylpentadecyl)-
Acibenzolar-S-methyl
DIMETHYLDIBENZYLIDENE SORBITOL
TRIFLUSULFURON
Imidacloprid
Isoxaflutole
Alachlor ethanesulfonic acid (ESA)
Flufenacet
Kresoxim-methyl
Cylindrospermopsin
BUTANEDIOIC ACID, SULFO-1 ,4-DIISODECYL ESTER,
Dibromochloroacetonitrile
Ceriva statin
Phosphorous acid, bis[2,4-bis(1 ,1-dimethylethyl)-6-
CALCIUMDODECYLPHENOXYBENZENEDISULFONATE
Cloransulam-methyl
2-(4,6-DIPHENYL-1,3,5-TRIAZIN-2-YL)-5-
AMMONIUM ZIRCONIUM HYDROXY CITRATE
AMMONIUM ZIRCONIUM HYDROXY LACTATE
AMMONIUM ZIRCONIUM CITRATE HYDROXY LACTATE
POLYETHYLENE GLYCOL MONOISOTRIDECYL ETHER
Aluminum, hydroxybis[2, 4,8,1 0-tetrakis(1,1-dimethylethyl)-6-
Metolachlor oxanilic acid (OA)
1,3,2-Dioxaphosphorinane, 5-butyl-5-ethyl-2-[2,4,6-tris(1,1-
2-PROPENOIC ACID, POLYMERS WITH N.N-DI-2-
HEXANEDIOICACID, POLYMER WITH N-(2-
Metolachlor ethanesulfonic acid (ESA)
Alachlor oxanilic acid (OA)
Carbamic acid, (chlorocarbonyl)[4-(trifluoromethoxy)phenyl]-,
1,4-BENZENEDICARBOXYLICACID, POLYMER WITH 1,4-
STYRENE-MALEIC ANHYDRIDE RESIN, PARTIAL
Fatty acids, C10-13-branched, vinyl esters
Acetochlor oxanilic acid (OA)
Acetochlor ethanesulfonic acid (ESA)
1 ,6-Hexanediamine, N,N'-bis(2,2,6,6-tetramethyl-4-
Phosphorothioic acid, O,O,O-triphenyl esters, tert-Bu derivs.
1 ,6-Hexanediamine, N,N'-bis(2,2,6,6-tetramethyl-4-
Silver-108m
Silver-IIOm
Technetium-99m
Nominated






























































Yes


Yes












Yes



Yes
Yes












Draft
PCCL3



Yes


Yes



Yes

Yes






































Yes










Yes


Yes












Yes



Yes
Yes




Yes
Yes






Final
PCCL3



Yes


Yes



Yes

Yes






































Yes
Yes
Yes
Yes







Yes


Yes












Yes



Yes
Yes




Yes
Yes






Draft
CCL 3



Yes


Yes



Yes



















































Yes


Yes












Yes



Yes
Yes




Yes
Yes






Public
Comment










Yes








Yes















Yes






Yes










Yes











Yes

Yes










Yes



Yes













Final
CCL 3



Yes


Yes



Yes



















































Yes


Yes












Yes



Yes
Yes




Yes
Yes






CCL 2






























































Yes

































CCL1






























































Yes

































        AS-60

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
378784522
378784533






























































































Common Name
Tellurium-129m
Tellurium-131m
1 ,1 ,1-Tribromo-2-bromo-2-chloroethane
1,1,1-Trichloro-2-butanone
1,1-Bromochloropropanone
1 ,2-Bis(1 -methylethenyl)-benzene
1,2-Dioxopropanoic acid
1,3,3-Trimethyl-7-oxabicyclo-[4.1.0]-heptane-2,5-dione
1-[4-(1-Hydroxy-1-methylethyl)phenyl]-ethanone
1-[4-(1-Methylethenyl)phenyl]-ethanone
1-Bromo-1,1-dichloropropanone
1-Chloro-2-ethoxy-2-methoxy ethane
1-Chloro-3,3,3-trichloro-1-propen-1-amine
1-Ethoxy-1-hydroxymethane
1-Hydroxy-3-methyl-2-hexene
2,2,4-Trichloro-1,3-cyclopentenedione
2,2-Dichloro-3-pentanone
2,3-Dichloro-3-bromopropanenitrile
2-[2-Ethyl-6-methylphenyl)amino]-1-propanal
2-Chloro-2,6-diethylacet-anilide
2-Chloro-3-(dichloromethyl)-butenedioic acid
2-Chloro-3-methyl-cis-butenedioic acid
2-Chlorobutenedioic acid
2-Ethyl-3-methyl maleic acid
2-Methyl-3,3-dichloro-2-propenyl dichloromethyl ether
3,4-Dichlorobutanenitrile
3'-AZIDO-3'-DEOXYTHYMIDINE + 2',3'-DIDEOXYINOSINE
3'-AZIDO-3'-DEOXYTHYMIDINE/2',3'-DIDEOXYCYTIDINE
3-Bromopropylchloromethyl ether
3-Chloro-2-butanol acetate
3-METHYL-6-METHOXY-2-AMINO-BENZOTHIAZOLIUM
4,5-Dichloro-2-pentanol
4-Chloro-3-keto-1-butanal
4-Dodecyl-5-ethyl-2(5H)furanone
4-nonylphenoldiethoxylate
4-octyl p h en ol d ieth oxyl at e
4-octyl p h en ol m on oeth oxyl ate
5,5,5-Trichloro-4-oxopentanoic acid
5-Hydroxy-5-trichloromethyl-2-furanone
ACRYLONITRILE-STYRENE-CO-ETHYLENEDIAMINE
ALKENYL(C16-18)DIMETHYLETHYLAMMONIUM
ALKOXY(C10-16)-2,3-EPOXYPROPANE
ALKYL(C10-20)DIMETHYLBENZYLAMMONIUM CHLORIDE
ALKYL(C4 C8)PHENOL
ALKYL(C7-12)BENZENE
ALKYL(C7-12)NAPTHALENE
ALPHA-(2,4,6-TRIISOBUTYLPHENYL)-OMEGA-
ALPHA-(P-NONYLPHENYL)-OMEGA-
ALPHA, ALPHA'-(METHYLENEBIS(4-(1 ,1 ,3,3-
ALPHA/BETATHUJONE MIXTURE
alpha- Amylase derived from Bacillus licheniformis carrying a
Alpha-amylase derived from Bacillus licheniformis carrying a
alpha- Amylase derived from Bacillus licheniformis carrying a
Aluminum chloride hexahydrate
AMMONIA/ETHYLENE DICHLORIDE/ SODIUM
AMMONIUM 5, 5-BIS((PERFLUOROALKYL(C2-
AMMONIUMBIS(2,2-BIS((PERFLUOROALKYL(C2-
AMMONIUM FRUCTOHEPTONATE
ANTIOXIDANT MODEL (TRAMP) - NAO (SPINACH
Arabinogalactan from Eastern Larch (Larix laricina)
Arabinogalactan from Larix occidentalis
ARASCO (arachidonic acid-rich single-cell oil)
ARASCO (arachidonic acid-rich single-cell oil) and DHASCO
Aspartic proteinase derived from Aspergillus oryzae carrying
ASPHALT, PARAFFINIC
AZT + ISONIAZID (AIDS INITIATIVE)
AZT + METHADONE HCL (AIDS)
AZT + NITAZOXANIDE (AIDS INITIATIVE)
AZT +PYRAZINAMIDE COMBINATION (AIDS INITIATIVE)
AZT + RIFAMPIN (AIDS INITIATIVE)
AZT +TMP/SMX (MIXTURE) COMBINATION
Bifidobacterium lactis strain Bb12 and Streptococcus
BLACK NEWSPRINT INK
Boh en in
Bromoamine
Bromochlorom ethyl acetate
Butanone-2, 4-chloro-4,4-difluoro
BUTENOICACID
Calcium casein peptone-calcium phosphate
CAMPHOR FATTY ACID ESTERS
Carbohydrase enzyme preparation from Aspergillus oryzae,
Carrot fiber
Cassia gum from Cassia tora/obtusifolia
CASTOR OIL, POLYOXYETHYLATED (42 MOLES
CATIONIC SOY PROTEIN, HYDROLYZED
CHEMICAL MIXTURE-DRINKING WATER
Chlorine dioxide generated from particles (<30[jm)
Ch I orod ib rom oaceta Id ehyde
Chromium picolinate; Ginkgo biloba leaf extract; and
cis-2,3,4-Trichloro-2-butenenitrile
cis-Propiconazol
Coagulated potato protein, hydrolyzed potato protein, or
Cobalt compounds
Composite filtration media (diatomaceous earth and perlite)
Crospovi done- cranberry juice extract
Dacthal mono/di-acid degradate
Nominated
































































































Draft
PCCL3




























































































Yes


Yes
Final
PCCL3




























































































Yes


Yes
Draft
CCL 3
































































































Public
Comment










Yes





















































































Final
CCL 3
































































































CCL 2
































































































CCL1
































































































        A5-61

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
































































































Common Name
Dextranase from Chaetomium gracile
DHASCO (docosahexaenoic acid-rich single-cell oil) and
Diacylglycerol oil
DIAMINES DERIVED FROM DIMERIZED VEGETABLE OIL
Diazinon oxygen analog
Dibromoamine
Didealkylatrazine
DIESEL FUEL MARINE
Dl ETHYL PHTHALATE/DIMETHYL PHTHALATE
Dihydro-4,5-dichloro-2-(3H)-furanone
DIMETHYLPOLYSILOXANE- BETA- PHENYL ETHYL
Docosahexaenoic acid-rich oil from tuna (DHA-rich tuna oil)
ETHYLENE-METHACRYLIC ACID COPOLYMER,
ETHYLENE-METHACRYLIC ACID COPOLYMER, CALCIUM
ETHYLENE-METHACRYLIC ACID COPOLYMER,
ETHYLENE-METHACRYLIC ACID COPOLYMER, PARTIAL
ETHYLENE-METHACRYLIC ACID COPOLYMER, SODIUM
ETHYLENE-METHACRYLIC ACID COPOLYMER, ZINC
ETHYLENE-METHACRYLIC ACID- VINYL ACETATE
ETHYLENE-METHACRYLIC ACID- VINYL ACETATE
ETHYLENE-METHACRYLIC ACID- VINYL ACETATE
ETHYLENE-METHACRYLIC ACID- VINYL ACETATE
ETHYLENE-METHACRYLIC ACID- VINYL ACETATE
Exopeptidase derived from Aspergillus oryzae carrying a
Extract of Garcinia kola seed ("bitter cola")
FATTY ACID(C18), UNSATURATED, DIMER, PARTIAL
FATTY ACIDS, ANIMAL, POTASSIUM SALT
FATTY ACIDS, ANIMAL, ZINC SALT
Fish oil concentrate
Five enzyme preparations from Aspergillus niger:
Fructooligosaccharide
Glucose oxidase enzyme preparation from Aspergillus
Glycerol ester of gum rosin
Grape seed extract
Grape seed extract and grape skin extract
GUAR GUM, 2,3- EPOXYPROPYLTRIMETHYLAMMONIUM
GUM ROSIN, ALUMINUM SALT
GUM ROSIN, AMMONIUM SALT
GUM ROSIN, CALCIUM SALT
GUM ROSIN, DIMERIZED, GLYCEROL ESTER
GUM ROSIN, DISPROPORTIONATED, ALUMINUM SALT
GUM ROSIN, DISPROPORTIONATED, POTASSIUM SALT
GUM ROSIN, DISPROPORTIONATED, SODIUM SALT
GUM ROSIN, HYDROGENATED, GLYCEROL ESTER
GUM ROSIN, MAGNESIUM SALT
GUM ROSIN, PARTIAL POTASSIUM SALT
GUM ROSIN, PARTIAL SODIUM SALT
GUM ROSIN, PARTIALLY DIMERIZED
GUM ROSIN, PARTIALLY HYDROGENATED
GUM ROSIN, POTASSIUM SALT
GUM ROSIN, SODIUM SALT
GUM ROSIN, ZINC SALT
Hexanes
Hops beta acids
Hydrogenated starch hydrolysate
Ice structuring protein
INIT/PROM COMPARATIVE STUDY
INTERFERON AD (AIDS INITIATIVE)
INTERFERON AD + 3'-AZIDO-3'-DEOXYTHYMIDINE (AIDS
INTERFERON AD + DDC (AIDS INITIATIVE)
Invertase enzyme preparation from Saccharomyces
Isoamylase from Pseudomonas amyloderamosa
Isolated wheat protein
ISOPROPYL ALCOHOL(MANUFACTURING, STRONG-
KAOLIN, MODIFIED WITH ISOPROPYL TITANATE-
Laccase enzyme preparation produced by Aspergillus oryzae
Laminariajaponica broth and extract powder
LEAD CONTAMINATED SOIL
LEAD ORES
Lipase derived from Aspergillus oryzae carrying a gene
Lipase derived from Aspergillus oryzae carrying a gene
Lipase enzyme preparation from Aspergillus niger
Lipase enzyme preparation from Aspergillus oryzae
Lipase enzyme preparation from Aspergillus oryzae carrying
Lipase from Candida rugosa
Lipase from Penicillium camembertii

Lutein esters
MAGNETIC FIELDS (EMF)
MAGNETIC FIELDS + DMBA INITIATION PROMOTION
Malathion oxygen analog
Manganese compounds
MARINE OIL FATTY ACIDS SOAPS, HYDROGENATED
Mesquite (Prosopis spp.) wood alcoholic extract
Mesquite wood alcoholic extract
METHACRYLATE-CHROMIC CHLORIDE COMPLEX,
METHACRYLATE-CHROMIC CHLORIDE COMPLEX,
METHYLATED POLY(N-1,2-DIHYDROXYETHYLENE- 1,3-
Milk thistle extract
Milk-derived lactoferrin
MONTAN WAX FATTY ACIDS, OXIDIZED, GLYCEROL
Mycoprotein
N-DIALKYL(C12-C18)BENZYLMETHYLAMMONIUM
Nickel compounds
Nine Botanicals: Chrysanthemum; Licorice; Honeysuckle;
nonylphenol, diethoxy-(total)
Nominated
































































































Draft
PCCL3




Yes
























































































Yes


Final
PCCL3




Yes
























































































Yes


Draft
CCL 3
































































































Public
Comment








Yes























































































Final
CCL 3
































































































CCL 2
































































































CCL1
































































































        AS-62

-------
Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN
































































































Common Name
NTP 90 DIET STUDY
NTP 91/92 DIET STUDY
NTP-2000 DIET
NTP-88 DIET STUDY (EGMBE)
NTP-88 DIET STUDY (EGMEE)
NTP-88 DIET STUDY (EGMME)
NTP-88 DIET STUDY (M-NITROTOLUENE)
NTP-88 DIET STUDY (O-NITROTOLUENE)
NTP-88 DIET STUDY (P-NITROTOLUENE)
OCTYLPHENOL POLY(ETHYLENE OXIDE-CO-
0-PHTHALIC ACI D MODIFI ED HYDROLYZED SOY
OXIDIZED SOY ISOLATE
OZONE/NNK
PARRAFFIN (012-20) SULFONATE
Pectate lyase enzyme preparation from Bacillus subtilis
Pectin esterase derived from Aspergillus oryzae carrying a
Pectin lyase derived from Trichoderma reesei carrying a
PEG-20 LANOLIN ADDUCT
PEG-25 GLYCEROL ADDUCT
PEG-40 STEARATE
PESTICIDE/FERTILIZER CONTAMINATION-MIXTURE 2
PESTICIDE/FERTILIZER CONTAMINATION-MIXTURE 3
Phytosterol esters
Phytosterols
Plant sterols/Plant sterol esters
POLY(12-HYDROXYSTEARIC ACID-CO- PEG 1500),
POLY(12-HYDROXYSTEARIC ACID-CO-PEG 4000),
POLY(1-ALKENE-CO-4-METHYL-1-PENTENE)
POLY(ACRYLICACID-CO-ACRYLONITRILE-CO-
POLY(ACRYLIC ACID-CO-BUTYL ACRYLATE-CO-
POLY(ACRYLIC ACID-CO-BUTYL ACRYLATE-CO-
POLY(ACRYLONITRILE-CO-BUTADIENE-CO-
POLY(ADIPIC ACID-CO-PHTHALIC ACID-CO-
POLY(ALKYL (C1 2-C22) METHACRYLATE-CO- BUTYL
POLY(ALLYLMETHACRYLATE-CO-VINYLIDENE
POLY(AMIDE-IMIDE) RESIN
POLY(BENZOIC ACID-CO-GLYCERIN-CO- PHTHALIC
POLY(BIS(HEXAMETHYLENE)TRIAMINE-CO-1,2-
POLY(BUTENE-CO-ETHYLENE), LOW MW
POLY(BUTYL ACRYLATE-CO-ETHYL ACRYLATE-CO-
POLY(CAPROLACTAM-CO-DIETHYLENETRIAMINE-CO-
POLY(COUMARONE-CO-FORMALDEHYDE-CO-INDENE-
POLY(COUMARONE-CO-INDENE-CO-PHENOL-CO-
POLY(DI BUTYL FUMARATE-CO-DIBUTYL MALEATE- CO-
POLY(DI BUTYL MALEATE-CO-GLYCIDYL
POLY(DIGLYCOLICACID-CO-PROPYLENEGLYCOL),
POLY(DIPENTENE-CO-ALPHA-PINENE-CO-BETA-
POLY(ETHYL FUMARATE-CO-VINYL CHLORIDE)
POLY(ETHYLMETHACRYLATE-CO-METHYL-
POLY(ETHYLENE-CO-METHACRYLATE)
POLY(FORMALDEHYDE-CO-PHENOL-CO-TERPENE)
POLY(GLYCERIN-CO- PHTHALIC AN HYDRIDE-CO- VINYL
POLY(HEPTYL FUMARATE-CO-VINYL CHLORIDE)
POLY(HEXYL FUMARATE-CO-VINYL CHLORIDE)
POLY(N-METHYL-BIS(3-AMINOPROPYL)AMINE-CO-
POLY(OCTYL FUMARATE-CO-VINYL CHLORIDE)
POLY(OXYCAPROYL)DIOLS, M W > 500
POLY(OXYCAPROYL)TRIOLS, M W> 500
POLY(PHENOL-CO-TERPENE)
POLY(PROPYL ACRYLATE-CO-VINYLIDENE CHLORIDE)
POLY(PROPYL FUMARATE-CO- VI NYLIDENE CHLORIDE)
POLYARYLSULFONE RESIN
POLYETHYLENEAMINOSTEARAMIDE ETHYL SULFATE
Polyglycerol polyricinoleic acid
POLYOXYBUTYLENE-POLYOXYPROPYLENE-
POLYOXYETHYLENE (MIN. 15 MOLS) ESTER OF ROSIN
POLYOXYETHYLENE (MW200) DIBENZOATE
POLYOXYPROPYLENE (MIN. 20 MOLS) OLEATE BUTYL
POLYOXYPROPYLENE-POLYOXY ETHYL ENEGLYCOL
POLYPHOSPHORIC ACID-TRIETHANOLAMINE PRODUCT
POLYURETHANE, ANIONIC
Pork collagen
PPG-20 BUTYL ETHER
PPG-3 TRIDECYL ALCOHOL SULFATE
PPG-40-BUTYL ETHER
PPG-69
PREVENTION 1 (FLAXSEED OIL + MELATONIN)
PREVENTION 10 (SOY ISOFLAVONE CONCENTRATE)
PREVENTION 2 (SILYMARIN + MELATONIN)
PREVENTION 4 (MELATONIN + CURCUMIN)
PREVENTION 4 (MELATONIN+INDOLE-3-CARBINOL)
PREVENTION 6 (ISOFLAVONE CONCENTRATE)
PREVENTION 6 (LOW ISOFLAVONE SOY PROTEIN
PREVENTION 7 (FEED CONTROLS)
Protein preparation from animal blood
Pullulanase derived from Bacillus licheniformis carrying a
Pullulanase derived from Bacillus subtilis carrying a gene
QUATERNIUM-8
RETINOID PROJECT 1
RETROVIRAL VECTORS
ROSIN ESTERS MODIFIED WITH XYLENOL-
ROSIN, DISPROPORTIONATED, ALUMINUM SALT
ROSIN, FORMALDEHYDE MODIFIED
ROSIN, HYDROGENATED, ALUMINUM SALT
ROSIN, HYDROGENATED, MAGNESIUM SALT
ROSIN, MALEIC ANHYDRIDE-PHTHALIC ANHYDRIDE
Nominated
































































































Draft
PCCL3
































































































Final
PCCL3
































































































Draft
CCL 3
































































































Public
Comment
































































































Final
CCL 3
































































































CCL 2
































































































CCL1
































































































        AS-63

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Final CCL 3 Chemicals:
Identifying the Universe
EPA815-R-09-006
     August 2009
CASRN



























































































Common Name
ROSIN, MODIFIED WITH ALKYL(C1-C9)PHENOL-
ROSIN, PARTIALLY DIMERIZED, ALUMINUM SALT
ROSIN, PARTIALLY DIMERIZED, MAGNESIUM SALT
ROSIN, PARTIALLY DIMERIZED, PEG ESTER
ROSIN, PARTIALLY HYDROGENATED, GLYCEROL
RUBBER LATEX, CREPE
RUBBER LATEX, NATURAL
Saccharomyces cerevisiae strain ML01 carrying a gene
SALTS OF ALPHA-OLEFIN(C10-18)SULFONATE
Seaweed-derived calcium
Shrimp-derived chitosan
Silk protein food powder
SILVER CHLORIDE-COATED TITANIUM DIOXIDE
Silver compounds
Small planktivorous pelagic fish body oil
SODIUM ALPHA-ALKYL(C12-15)-OMEGA- HYDROXYPOLY
SODIUM ISODODECYLPHENOXYPOLYETHOXY (40
SODIUM MONO- AND
SODIUM NAPHTHALENESULFONATE AND ITS METHYL,
SODIUM N-DODECYLPOLYETHOXY (50 MOLES)
Solin oil (low linolenic acid flaxseed oil or low linolenic acid
Soy isoflavone extract
Spirulina
STYRENE-MALEIC ANHYDRIDE COPOLYMER,
SUCROSE FATTY ACID ESTERS
Synthetic lycopene
SYNTHETIC WAX POLYMER
Tall oil phytosterols
TALL OIL ROSIN, ALUMINUM SALT
TALL OIL ROSIN, AMMONIUM SALT
TALL OIL ROSIN, DIMERIZED
TALL OIL ROSIN, DIMERIZED, GLYCEROL ESTER
TALL OIL ROSIN, DISPROPORTIONATED, ALUMINUM
TALL OIL ROSIN, DISPROPORTIONATED, POTASSIUM
TALL OIL ROSIN, DISPROPORTIONATED, SODIUM SALT
TALL OIL ROSIN, MAGNESIUM SALT
TALL OIL ROSIN, MALEATED, PENTAERYTHRITOL
TALL OIL ROSIN, PARTIAL POTASSIUM SALT
TALL OIL ROSIN, PARTIAL SODIUM SALT
TALL OIL ROSIN, PARTIALLY DIMERIZED
TALL OIL ROSIN, PARTIALLY HYDROGENATED
TALL OIL ROSIN, PENTAERYTHRITOL ESTER
TALL OIL ROSIN, POTASSIUM SALT
TALL OIL ROSIN, SODIUM SALT
TALL OIL ROSIN, ZINC SALT
TALL OIL ROSIN-FORMALDEHYDE POLYMER
TAMARIND SEED KERNEL POWDER
Tasteless smoke
Tefluthrin metabolite [R119364]
Tefluthrin metabolite [R152912]
tert-Butyl maleic acid
trans-2,3,4-Trichloro-2-butenenitrile
Transglutaminase from Streptoverticillium mobaraense
trans- Propiconazol
Trichloropropenenitrile
TRIETHYLENE GLYCOL ADIPIC ACID MONOESTER
TRIETHYLENETETRAMINE MONOACETATE, PARTIALLY
URETHANE+ETHANOL (COMBINATION)
Vanadium compounds
Vegetable oil phytosterol esters
VEGETABLE OIL, SULFONATED POTASSIUM SALT
VINYL DIMETHYL POLYSILOXANE, REACTION PRODUCT
Whey mineral concentrate
Whey protein isolate and dairy product solids
White mineral oil, USP (viscosity ISO 100)
WOOD ROSIN, ALUMINUM SALT
WOOD ROSIN, AMMONIUM SALT
WOOD ROSIN, DIMERIZED
WOOD ROSIN, DIMERIZED, GLYCEROL ESTER
WOOD ROSIN, DISPROPORTIONATED, ALUMINUM SALT
WOOD ROSIN, DISPROPORTIONATED, POTASSIUM
WOOD ROSIN, DISPROPORTIONATED, SODIUM SALT
WOOD ROSIN, HYDROCARBON INSOLUBLE
WOOD ROSIN, HYDROGENATED, GLYCEROL AND
WOOD ROSIN, HYDROGENATED, PENTAERYTHRITOL
WOOD ROSIN, MAGNESIUM SALT
WOOD ROSIN, MALEATED
WOOD ROSIN, MALEATED, PENTAERYTHRITOL ESTER
WOOD ROSIN, METHYL ESTER
WOOD ROSIN, PARTIAL POTASSIUM SALT
WOOD ROSIN, PARTIAL SODIUM SALT
WOOD ROSIN, PARTIALLY DIMERIZED
WOOD ROSIN, PARTIALLY DIMERIZED, GLYCEROL
WOOD ROSIN, PARTIALLY HYDROGENATED
WOOD ROSIN, PARTIALLY HYDROGENATED, METHYL
WOOD ROSIN, POTASSIUM SALT
WOOD ROSIN, ZINC SALT
Xylanase derived from Fusarium venenatum carrying a gene
XYLENE-FORMALDEHYDE RESINS CONDENSED WITH
Zinc compounds
ZINCNAPHTHENATE-DEHYDROABIETYLAMINE
Nominated



























































































Draft
PCCL3



























































































Final
PCCL3



























































































Draft
CCL 3



























































































Public
Comment



























































































Final
CCL 3



























































































CCL 2



























































































CCL1



























































































        AS-64

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